Toxigenic Clostridium perfringens from a parvovirus-infected dog.
A strain of Clostridium perfringens, type A, has been isolated from the intestine of a dog which died from parvovirus infection. This Clostridium strain produces a toxin which can be detected by counterimmunoelectrophoresis, using C. difficile antitoxin, and produces cytotoxicity in WI-38 cell culture. Cytopathology can be blocked by C. difficile antitoxin. Its role in canine parvovirus infection is unknown.
D000818:Animals; D001427:Bacterial Toxins / Q000276:immunology*; D002460:Cell Line; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003378:Counterimmunoelectrophoresis; D003601:Cytotoxicity Tests, Immunologic; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D007422:Intestines / Q000382:microbiology; D008168:Lung; D010321:Parvoviridae; D014777:Virus Diseases / Q000382:microbiology / Q000662:veterinary*
D001427:Bacterial Toxins