Feeding responses of riboflavin-deficient rats to energy dilution, cold exposure and glucoprivation.
Feeding in response to various stimuli, was investigated in riboflavin-deficient rats. The animals failed to increase their food intake when fed energy-diluted diets with cellulose contents of either 15 or 30%. Furthermore, they lost reactivity to the hyperphagic action of either insulin of 2-deoxy-D-glucose regardless of a perfect response in blood glucose. Cold exposure (10 degrees), however, stimulated energy intake of the deficient rats to the same extent as that of the riboflavin-supplemented normal rats. These findings indicate that there was an operative thermostatic, but not a glucostatic control in regulation of energy intake of the riboflavin-deficient rats.
D000818:Animals; D001835:Body Weight; D003080:Cold Temperature; D003847:Deoxyglucose / Q000494:pharmacology; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage*; D002149:Energy Intake; D005247:Feeding Behavior; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D006963:Hyperphagia / Q000139:chemically induced; D007328:Insulin / Q000494:pharmacology; D008297:Male; D051381:Rats; D012257:Riboflavin Deficiency / Q000378:metabolism*
D004043:Dietary Fiber; D007328:Insulin; D003847:Deoxyglucose; D005947:Glucose