[Clinical and epidemiologic aspects of cryptococcosis in Kinshasa. Apropos of 15 personal cases].
The authors have recorded 15 cases in their eighteen months of hospital practice in Kinshasa. Fever and meningo-encephalitis are not specific symptoms and the detection of yeasts in the spinal fluid or sometimes in a lymph node is necessary to support the diagnosis. Direct examinations of the cerebro-spinal fluid is most often sufficient and easy for patients who have already had, in most cases, a long evolution giving way to an important proliferation of yeasts. Only one patient recovered by a treatment associating amphotericin B and ketoconazole. Another one, after an apparent recovery with the same treatment, died rapidly of acute tuberculosis.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000666:Amphotericin B / Q000627:therapeutic use; D002648:Child; D003453:Cryptococcosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D015023:Democratic Republic of the Congo; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D007654:Ketoconazole; D008297:Male; D008825:Miconazole / Q000627:therapeutic use; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D012737:Sex Factors
D007093:Imidazoles; D010879:Piperazines; D008825:Miconazole; D000666:Amphotericin B; D007654:Ketoconazole
Aspects cliniques et épidémiologiques de la cryptococcose à Kinshasa. A propos de 15 cas personnels.