[Cellular immunity study of multiple sclerosis in the lymphocyte blast transformation reaction to the viruses of acute human encephalomyelitis, herpes and measles].
The blast transformation test revealed a high level of lymphocyte sensitization to human acute encephalomyelitis virus in 12 out of 29 (41.9%) patients with multiple sclerosis in the early stages of the disease and in the period of exacerbation in patients with long-term disease. The pattern of the blast transformation test in response to herpes simplex and measles viruses did not depend on the duration of the disease. High, moderate, and low levels of lymphocyte blast transformation reaction to herpes and measles viruses were observed in patients with multiple sclerosis with similar average durations of the disease.
D000328:Adult; D002908:Chronic Disease; D004668:Encephalitis Viruses / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007114:Immunization; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008459:Measles virus / Q000276:immunology*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000276:immunology*; D018139:Simplexvirus / Q000276:immunology*
Izuchenie kletochnogo immuniteta u bol'nykh mnozhestvennym sklerozom v reaktsii blasttransformatsii limfotsitov k virusam ostrogo éntsefalomietita cheloveka, gerpesa i kori.