title: Blood groups, serum proteins, and red cell enzymes in the Nganasans (Tavghi)-reindeer hunters from Taimir Peninsula.
abstract: The Nganasans are made up of two recently tribal populations. These, the Avam and Vadey, were established in the seventeenth century from small reindeer hunting bands, themselves apparently descended from the Yukaghir. Data on 13 blood systems have been described for the first time in the Vadey Nganasans, and the results compared with those previously reported for the two Avam subgroups. As a whole, the Nganasans are characterized by low frequency of B blood group, high frequencies of Ns, cDE, Fy(a), Hp(2), absence of A2, P(c), K, and apparently an absence of cde alleles or haplotypes. Measurement of intrapopulation heterogeneity reveals significant divergence among the two Avam subdivisions (chi 2/16=57.59; P less than 0.001), as well as between the total Avam and Vadey (chi 2/17=79.31; P less than 0.001). Founder principle, and local genetic drift, are believed to account for the greater difference between the Avam and Vadey subgroups than that observed between the two Avam populations. The Nganasans of the Taimir Peninsula appear to be the last group of reindeer hunters remaining in Northern Siberia. For ages they have lived in relative isolation, and therefore are the least touched genetically, either by surrounding herding groups originating in Southern Siberia, or by recent Caucasian admixture.
mesh_terms: D000483:Alleles; D001789:Blood Group Antigens / Q000235:genetics*; D001798:Blood Proteins / Q000235:genetics*; D004641:Emigration and Immigration / Q000266:history; D004912:Erythrocytes / Q000201:enzymology*; D005006:Ethnicity; D005787:Gene Frequency; D005819:Genetic Markers; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D010641:Phenotype; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics*; D012800:Siberia
chemical_list: D001789:Blood Group Antigens; D001798:Blood Proteins; D005819:Genetic Markers; D010744:Phosphoric Monoester Hydrolases