Env gene products of AKR dual-tropic viruses: examination of peptide maps and cell surface expression.
The env gene products of nine AKR dual-tropic murine leukemia viruses were compared by peptide mapping and were assayed for expression on the cell surface of infected fibroblasts. Seven virus isolates expressed the env gene polyprotein on the cell surface. The env gene products of six of the seven viruses had identical peptide maps. The analysis of structure and expression of env gene products carried out in this study characterizes a subset of dual-tropic murine leukemia viruses shown by others to be thymotropic.
D000406:AKR murine leukemia virus / Q000032:analysis* / Q000235:genetics / Q000276:immunology; D000818:Animals; D000956:Antigens, Viral; D002462:Cell Membrane / Q000032:analysis*; D005814:Genes, Viral; D009052:Leukemia Virus, Murine / Q000032:analysis*; D051379:Mice; D010455:Peptides / Q000032:analysis; D011995:Recombination, Genetic; D013601:T-Lymphocytes / Q000382:microbiology; D014759:Viral Envelope Proteins; D014764:Viral Proteins / Q000032:analysis*
D000956:Antigens, Viral; D010455:Peptides; D014759:Viral Envelope Proteins; D014764:Viral Proteins