A new principle of regulation of enzymic activity. Activation and regulation of human polymorphonuclear leukocyte collagenase via disulfide-thiol exchange as catalysed by the glutathione cycle in a peroxidase-coupled reaction to glucose metabolism.
D004789:Enzyme Activation; D005947:Glucose / Q000378:metabolism*; D005949:Glucose Oxidase / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D003012:Microbial Collagenase / Q000097:blood*; D008970:Molecular Weight; D009249:NADP / Q000378:metabolism; D009504:Neutrophils / Q000201:enzymology*; D010544:Peroxidases / Q000378:metabolism*
D009249:NADP; D006861:Hydrogen Peroxide; D005949:Glucose Oxidase; D010544:Peroxidases; D003012:Microbial Collagenase; D005978:Glutathione; D005947:Glucose