Evidence from in vitro murine immunologic assays that some phenolic food additives may function as antipromoters by lowering intracellular cyclic GMP levels.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D003994:Bucladesine / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D002273:Carcinogens / Q000494:pharmacology*; D002478:Cells, Cultured; D006152:Cyclic GMP / Q000378:metabolism*; D005260:Female; D005503:Food Additives / Q000494:pharmacology*; D007108:Immune Tolerance / Q000187:drug effects*; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000517:prevention & control; D010636:Phenols / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D002273:Carcinogens; D005503:Food Additives; D010636:Phenols; D003994:Bucladesine; D006152:Cyclic GMP; D002118:Calcium