[Proliferative glomerulopathy in pneumococcal septicemia in a patient with lupus (author's transl)].
Acute glomerulopathy due to pneumococcal infection occurred in a patient with chronic discoid lupus. The onset of renal involvement in this context suggested that cutaneous lupus may have developed into systemic lupus erythematosus. Renal biopsy established the correct diagnosis. The physiopathology of glomerular involvement in lupus and infections is discussed. Attention is drawn to the significance of complement activation, either by the classical or the alternative pathways according to the etiology.
D000328:Adult; D003167:Complement Activation; D003176:Complement C3 / Q000032:analysis; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008179:Lupus Erythematosus, Discoid / Q000150:complications*; D011008:Pneumococcal Infections / Q000276:immunology*; D018805:Sepsis / Q000150:complications* / Q000276:immunology
D003176:Complement C3
Glomérulopathie proliférative au cours d'une septicémie à pneumocoques compliquant l'évolution d'une maladie lupique.