Cytochrome c reduction by triiodothyronine (T3).
Triiodothyronine (T3), the active thyroid hormone, reduced cytochrome c non-enzymatically. This reduction was partially inhibited by superoxide dismutase (SOD). Thyroxine (T4) was only minimally effective as a reductant in this system. The effect of T3 on mitochondrial oxidative phosphorylation may involve a direct redox mechanism.
D003574:Cytochrome c Group / Q000378:metabolism*; D007700:Kinetics; D010084:Oxidation-Reduction; D013482:Superoxide Dismutase / Q000378:metabolism; D013974:Thyroxine / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism*
D003574:Cytochrome c Group; D014284:Triiodothyronine; D013482:Superoxide Dismutase; D013974:Thyroxine