Beta-Endorphin. Synthesis and radioreceptor-binding activity of the ostrich hormone.
Ostrich beta-endorphin has been synthesized by the solid-phase method. Opiate activity in a radioreceptor binding assay is about seven times that of human beta-endorphin. Structural differences within positions 6-15 account for the increased binding potency.
D000818:Animals; D001681:Biological Assay; D001717:Birds; D001921:Brain / Q000378:metabolism*; D004723:Endorphins / Q000138:chemical synthesis* / Q000378:metabolism; D007202:Indicators and Reagents; D011957:Receptors, Opioid / Q000378:metabolism*; D001615:beta-Endorphin
D004723:Endorphins; D007202:Indicators and Reagents; D011957:Receptors, Opioid; D001615:beta-Endorphin