Seroepidemiology of Epstein-Barr virus in pregnant women.
Sera from 2,000 women in the early stages of pregnancy in 1980-1981 were tested for antibodies to Epstein-Barr virus. Of the 2,000 women, 1,386 attended an obstetrical clinic (average age, 21 years) and 614 attended a private practice (average age, 28 years). Only eight (0.6%) of the women attending the obstetrical clinic were seronegative (less than or equal to 20 years, five [0.8%] of 650; 21-30 years, three [0.5%] of 648; and greater than or equal to 31 years, zero of 88), whereas 18 (2.9%) of the women attending the private practice were seronegative (less than or equal to 20 years, two [4.8%] of 42; 21-30 years, 12 [3.0%] of 388; and greater than or equal to 31 years, four [2.3%] of 184). Probable recent seroconversions were detected in 35 women. Sera from 185 women pregnant in 1959-1965 were tested for antibodies to Epstein-Barr virus; 17 (9%) were seronegative, compared with 26 (1.3%) of the women in 1980-1981 (P less than 0.01).
D000022:Abortion, Spontaneous; D000293:Adolescent; D000328:Adult; D000375:Aging; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D005260:Female; D006566:Herpesviridae Infections; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007021:Hypospadias; D007231:Infant, Newborn; D007234:Infant, Premature; D007236:Infant, Small for Gestational Age; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious
D000914:Antibodies, Viral