Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus.
Harvey murine sarcoma virus is a retrovirus which transforms cells by means of a single virally encoded protein called p21 has. We have determined the nucleotide sequence of 1.0 kilobase in the 5' half of the viral genome which encompasses the has coding sequences and its associated regulatory signals. The nucleotide sequence has identified the amino acid sequence of two additional overlapping polypeptides which share their reading frames and the carboxyl termini with p21 but which contain additional NH2-terminal amino acids.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D003673:Defective Viruses / Q000235:genetics*; D005814:Genes, Viral; D015689:Oncogene Protein p21(ras); D010446:Peptide Fragments; D014176:Protein Biosynthesis; D011487:Protein Conformation; D012367:RNA, Viral / Q000235:genetics; D009053:Sarcoma Viruses, Murine / Q000235:genetics*; D014764:Viral Proteins / Q000032:analysis / Q000235:genetics*
D010446:Peptide Fragments; D012367:RNA, Viral; D014764:Viral Proteins; D015689:Oncogene Protein p21(ras)