[Energy reactions in the skeletal muscles of rats following space flight on the Kosmos-936 biosatellite].
The respiration of mitochondria isolated from mixed skeletal muscles of hindlimbs of rats flown for 18.5 days on Cosmos-936 was investigated polarographically. At R + 10 hours the rate of mitochondrial respiration in different metabolic states during the oxidation of succinic acid and NAD-dependent substrates declined. The enzyme activity of mitochondrial cytochrome oxidase and cytosol lactate dehydrogenase diminished. At R + 25 days both aerobic and anaerobic oxidative processes increased, thus leading to the recovery of the parameters (sometimes they not only returned to the norm but exceeded it).
D000818:Animals; D003576:Electron Transport Complex IV / Q000378:metabolism; D004734:Energy Metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009132:Muscles / Q000201:enzymology*; D010084:Oxidation-Reduction; D051381:Rats; D013026:Space Flight; D013997:Time Factors; D014586:USSR
D007770:L-Lactate Dehydrogenase; D003576:Electron Transport Complex IV
Energeticheskie reaktsii v skeletnykh myshtsakh krys posle kosmicheskogo poleta na biosputnike "Kosmos-936".