[Metabolism of the organic phosphate regulators of oxygenation in cells of the erythrocyte series in birds and mammals].
In mammals, bisphosphoglycerate-synthase activity, whose assay methods are previously discussed, increases gradually along erythropoiesis, leading to a consequent enhancement of 2,3-bisphosphoglycerate formation. Avian erythrocytes, on the other hand, contain inositol-pentaphosphate as major organic phosphate starting from egg eclosion, which substitutes embrionary ATP and 2,3-BPG in the regulatory function. The IHP of phytase and the disappearance of 2,3-BPG synthesis, also inhibitor of enzyme activity, should be considered responsible for IPP accumulation.
D019794:2,3-Diphosphoglycerate; D010832:6-Phytase / Q000378:metabolism*; D000367:Age Factors; D000818:Animals; D001717:Birds / Q000097:blood*; D002642:Chick Embryo; D004163:Diphosphoglyceric Acids / Q000096:biosynthesis; D004912:Erythrocytes / Q000378:metabolism*; D004920:Erythropoiesis; D008322:Mammals / Q000097:blood; D010108:Oxyhemoglobins / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D010833:Phytic Acid / Q000096:biosynthesis; D051381:Rats; D013045:Species Specificity
D004163:Diphosphoglyceric Acids; D010108:Oxyhemoglobins; C019794:bisphosphoglycerate phosphatase; D019794:2,3-Diphosphoglycerate; D010833:Phytic Acid; D010744:Phosphoric Monoester Hydrolases; D010832:6-Phytase
Contribución al estudio del metabolismo de los fosfatos orgánicos reguladores de la oxigenación en células de la seie eritrocitaria en aves y mamíferos.