Extraskeletal osteogenic sarcoma after treatment for Wilms' tumor.
A large proportion of children with Wilms' tumor will become long-term disease-free survivors. A small number of these children are at risk of developing second malignant neoplasms. There have been no previous reports of osteogenic sarcoma of the chest wall following treatment of Wilms' tumor. Our patient was age seven years when he received surgery, radiation therapy and chemotherapy for Wilms' tumor, eight years when he received radiation and chemotherapy for pulmonary metastases of Wilms' tumor, and 13 years when he developed osteogenic sarcoma of the chest wall.
D002648:Child; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D009378:Neoplasms, Multiple Primary; D012516:Osteosarcoma / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*; D013909:Thorax; D009396:Wilms Tumor / Q000401:mortality / Q000473:pathology* / Q000628:therapy