title: [Effect of nitrite on cytochrome oxidase].
abstract: Nitrite causes changes in the optical and EPR spectra of cytochrome oxidase from heart and alters the spectral, redox and basic properties of cytochrome c. No utilization of nitrite by cytochrome oxidase was observed. However, nitrite inhibits the superoxide dismutase and oxidase activities of the enzyme. Changes in the properties of cytochrome oxidase were observed under effect of some products of nitrite reduction, e. g. nitric oxide, hydroxylamine, hydrazine; nitrate has no effect on the optical and EPR spectra or on the enzyme activity.
mesh_terms: D000818:Animals; D002417:Cattle; D004578:Electron Spin Resonance Spectroscopy; D003576:Electron Transport Complex IV / Q000378:metabolism*; D007700:Kinetics; D009206:Myocardium / Q000201:enzymology; D009573:Nitrites / Q000494:pharmacology*; D010084:Oxidation-Reduction; D013053:Spectrophotometry; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D009573:Nitrites; D013482:Superoxide Dismutase; D003576:Electron Transport Complex IV
vernacular_title: Vliianie nitrita na tsitokhromoksidazu.