[Incorporation of influenza virus antigens into the envelope of the avian oncornavirus].
The mixture of influenza virus and pseudotype of Rous sarcoma virus--RSV (PAB-A) grown in chick embryos or cell culture of chick fibroblasts produces a progeny which can be partially neutralized by a heterologous immune serum. The fraction of viral particles, the transformation activity of which is susceptible to suppression by both homologous anti-RSV (PAB-A) and heterologous serum, immune to influenza virus, amounts to approximately 20%. After passivation, these particles lose this property which suggests a non-genetical character of the phenomenon. Hence, dual infection results in phenotypic mixing and formation of particles with nucleoproteid of RSV (PAS-A) which contain antigens of avian sarcoma and influenza viruses in their envelopes.
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D001354:Avian Leukosis Virus / Q000276:immunology*; D002213:Capsid / Q000276:immunology*; D002472:Cell Transformation, Viral; D002642:Chick Embryo; D007106:Immune Sera / Q000276:immunology; D009980:Influenza A virus / Q000276:immunology*; D009500:Neutralization Tests; D009698:Nucleoproteins / Q000276:immunology; D010641:Phenotype; D014764:Viral Proteins / Q000276:immunology*; D014776:Virus Cultivation
D000956:Antigens, Viral; D007106:Immune Sera; D009698:Nucleoproteins; D014764:Viral Proteins
Vkliuchenie antigenov virusa grippa v obolochku ptich'ego onkornavirusa.