In vitro susceptibility of Haemophilus influenzae and neisseria gonorrhoeae to Ro 13-9904 in comparison with other beta-lactam antibiotics.
Ro 13-9904 has high in vitro activity, as does cefotaxime, against 57 Haemophilus influenzae and 60 Neisseria gonorrhoeae strains, including 5 and 11 beta-lactamase-producing strains in each group, respectively.
D002439:Cefotaxime / Q000031:analogs & derivatives* / Q000494:pharmacology; D002443:Ceftriaxone; D002511:Cephalosporins / Q000494:pharmacology*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006193:Haemophilus influenzae / Q000187:drug effects*; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000201:enzymology; D010406:Penicillins / Q000494:pharmacology*; D013183:Sputum / Q000382:microbiology; D001618:beta-Lactamases / Q000096:biosynthesis
D002511:Cephalosporins; D010406:Penicillins; D002443:Ceftriaxone; D001618:beta-Lactamases; D002439:Cefotaxime