[Effect of vanadium compounds on the enzymic activity in sarcolemma of developing muscles].
Sodium metavanadate (10(-4)-10(-6) M) stimulates the activity of adenylate cyclase and decreases the activity of Na+, K+-ATRase and 5'-nucleotidase in the sarcolemma fraction of chicken skeletal muscles at the embryonal and postembryonal developmental stages. Under conditions of a combined action of vanadate and guanylic nucleotides on the adenylate cyclase activity their effects are found to be potentiated. Epinephrine in vitro removes an inhibitory influence of vanadate on Na+, K+-ATPase from the third week of twe embryonal period. The restoring effect of epinephrine is blocked by propranol--a beta-adrenoblocker.
D015720:5'-Nucleotidase; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D007700:Kinetics; D024510:Muscle Development; D009132:Muscles / Q000196:embryology / Q000201:enzymology; D009708:Nucleotidases / Q000378:metabolism*; D012508:Sarcolemma / Q000201:enzymology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D014639:Vanadium / Q000494:pharmacology*
D014639:Vanadium; D009708:Nucleotidases; D015720:5'-Nucleotidase; D000262:Adenylyl Cyclases; D000254:Sodium-Potassium-Exchanging ATPase
Vliianie soedineniĭ vanadiia na aktivnost' nekotorykh fermentov sarkolemmy razvivaiushchikhcia skeletnykh myshts.