Fracture of the clavicle following radical neck dissection and postoperative radiotherapy: a case report and review of the literature.
The treatment of head and neck cancer with radiotherapy and radical neck dissection has many recognized complications. Radiotherapy in therapeutic doses can produce devascularization and weakening of bone. Radical neck dissection results in altered mechanics of the shoulder girdle and a disruption of normally balanced forces acting on the clavicle. An unusual case of clavicle fracture which is considered to have resulted from an interaction of the effects of these therapies is discussed. An approach for recognizing and distinguishing this entity by its time course, and radiographic and nuclide bone scan appearance is presented.
D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy / Q000601:surgery; D002968:Clavicle / Q000293:injuries* / Q000503:physiopathology / Q000528:radiation effects; D005598:Fractures, Spontaneous / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D037981:Neck Dissection / Q000009:adverse effects*; D011832:Radiation Injuries / Q000209:etiology*