title: Changes in the cytochrome c content during the aerobic adaptation of Paracoccus denitrificans.
abstract: Concentration of cytochrome c decreases when shaking anaerobically grown cells in a non-growth medium down to 50% of the original amount in the cell, depending on the degree of aeration. Only 10-20% of this amount can be found in the adaptation medium. The main portion of cytochrome c is degraded during the adaptation. Inhibitors of proteinases do not influence the degradation. Addition of mammalian cytochrome c fully prevents the degradation of bacterial cytochrome c but not its release from cells. Potassium hexacyanoferrate(III) exhibits a similar effect as oxygen. The degradation system is probably localized in the periplasmic space of the cells.
mesh_terms: D000222:Adaptation, Physiological; D000332:Aerobiosis; D003574:Cytochrome c Group / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D005292:Ferricyanides / Q000494:pharmacology; D010100:Oxygen / Q000494:pharmacology; D010231:Paracoccus denitrificans / Q000201:enzymology*; D011190:Potassium Cyanide / Q000494:pharmacology; D011479:Protamines / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology
chemical_list: D003574:Cytochrome c Group; D005292:Ferricyanides; D011479:Protamines; D011480:Protease Inhibitors; D011190:Potassium Cyanide; D010100:Oxygen; C028033:potassium ferricyanide