An analysis of altered attention in monkeys exposed to delta-9-tetrahydrocannabinol during development.
Monkey infants born to mothers treated chronically with 2.4 mg/kg delta-9-tetrahydrocannabinol (THC) showed an alteration in visual attention characterized by a failure to limit the duration of attention when looking at novel stimuli. Five off-spring of treated mothers were compared to nine controls in a standardized situation in which they could view slides through a small peephole. THC offspring looked longer at slides early in a session and during the first session in which a given slide was seen. The time of appearance of the peak duration in a series of attention episodes also differed between groups. These alterations in visual attention could have an influence on perceptual and cognitive processes.
D000818:Animals; D001288:Attention / Q000187:drug effects*; D004193:Discrimination Learning / Q000187:drug effects; D013759:Dronabinol / Q000494:pharmacology*; D005260:Female; D006185:Habituation, Psychophysiologic / Q000187:drug effects; D000882:Haplorhini; D007774:Lactation / Q000187:drug effects; D008297:Male; D008431:Maternal-Fetal Exchange / Q000187:drug effects; D011247:Pregnancy; D014796:Visual Perception / Q000187:drug effects
D013759:Dronabinol