Results of surgical treatment of lung metastases in children.
Between 1970 and 1979, 14 patients were operated on for pulmonary metastases. In 9 of these the primary tumour was a Wilms' nephroblastoma. Five out of the 14 patients are presently alive and free from disease (3 to 10 years after pulmonary resection). Primary tumours of the survivors were Wilms' tumour in 3 cases, an ovarian teratoma in one patient and a Ewing's sarcoma in one patient. Two of survivors had bilateral involvement and one had multiple metastases of one lung with pleural exudation. The disease-free interval was the same among the survivors and the non-survivors. It is apparent from the present material that some patients with a very poor prognosis as predicted from different prognostic factors can be cured after surgical excision of the metastases. The surgical procedure in children involves a very small risk and only moderate discomfort. An active surgical approach is therefore recommended.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002813:Chondrosarcoma / Q000556:secondary / Q000601:surgery; D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery; D012208:Rhabdomyosarcoma / Q000556:secondary / Q000601:surgery; D012512:Sarcoma, Ewing / Q000556:secondary / Q000601:surgery; D009396:Wilms Tumor / Q000556:secondary / Q000601:surgery