title: 97Ru-DMSA for delayed renal imaging.
abstract: Dimercaptosuccinic acid (DMSA) was labeled with 97Ru both with and without the addition of SnCl.2H2O. The tin-containing preparation was found to induce higher cortical deposition of 97Ru-DMSA than the tin-free preparation. Visualization of the renal cortex was excellent 4 to 48 hours after injection in normal dogs with renal insufficiency. It is concluded that 97Ru-(Sn+2)-DMSA is a potentially useful renal imaging agent when delayed scintigraphy is necessary because of decompensaton of the kidneys.
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D007668:Kidney / Q000000981:diagnostic imaging*; D051379:Mice; D011868:Radioisotopes; D011877:Radionuclide Imaging; D051381:Rats; D012428:Ruthenium; D004113:Succimer; D013438:Sulfhydryl Compounds; D013997:Time Factors
chemical_list: D011868:Radioisotopes; D013438:Sulfhydryl Compounds; D012428:Ruthenium; D004113:Succimer