Persistent infection with bovine herpesvirus type 1: rabbit model.
Persistent infection with bovine herpesvirus type 1 (BHV-1) was established in all rabbits after conjunctival inoculation of virus. Spontaneous reactivations of BHV-1 with and without the appearance of recurrent ocular lesions were observed in persistently infected rabbits. BHV-1 was reactivated predictably and shed from all persistently infected rabbits after the administration of dexamethasone. During all reactivations, BHV-1 isolation was restricted to the inoculated eye.
D000818:Animals; D002417:Cattle / Q000382:microbiology; D002418:Cattle Diseases / Q000382:microbiology*; D003228:Conjunctiva / Q000382:microbiology; D003907:Dexamethasone / Q000494:pharmacology; D004195:Disease Models, Animal; D005128:Eye Diseases / Q000662:veterinary; D006564:Herpesviridae / Q000254:growth & development / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000382:microbiology / Q000662:veterinary*; D011817:Rabbits; D013997:Time Factors
D003907:Dexamethasone