Cochlear transduction: an integrative model and review.
A model for cochlear transduction is presented that is based on considerations of the cell biology of its receptor cells, particularly the mechanisms of transmitter release at recepto-neural synapses. Two new interrelated hypotheses on the functional organization of the organ of Corti result from these considerations, one dealing with the possibility of electrotonic interaction between inner and outer hair cells and the other with a possible contributing source to acoustic emissions of cochlear origin that results from vesicular membrane turnover.
D000161:Acoustic Stimulation; D000818:Animals; D001307:Auditory Perception / Q000502:physiology; D003051:Cochlea / Q000502:physiology*; D003055:Cochlear Microphonic Potentials; D006198:Hair Cells, Auditory / Q000033:anatomy & histology / Q000502:physiology; D006199:Hair Cells, Auditory, Inner / Q000033:anatomy & histology / Q000502:physiology; D008954:Models, Biological; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission; D013680:Tectorial Membrane / Q000502:physiology; D000159:Vestibulocochlear Nerve / Q000502:physiology