title: Simultaneous gas chromatographic analysis of drugs of abuse on two fused-silica columns of different polarities.
abstract: A convenient and rapid gas chromatographic method for analysis of drugs of abuse has been developed. By installing two differently coated columns in a common split-splitless injector and connecting the column ends to a nitrogen-phosphorus detector and a flame ionization detector, considerable and accurate chromatographic information could be obtained from a single run. Quantitative analyses of amphetamine and some other drugs have been performed with the same instrumental set-up. Calibration graphs were evaluated and showed linearity in the concentration range chosen (0.5-10 mg/ml). By using an auto-sampler in combination with a BASIC program, both types of analyses can be performed routinely.
mesh_terms: D000661:Amphetamine / Q000032:analysis; D001322:Autoanalysis; D002849:Chromatography, Gas / Q000379:methods; D013287:Illicit Drugs / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D012822:Silicon Dioxide
chemical_list: D013287:Illicit Drugs; D004364:Pharmaceutical Preparations; D012822:Silicon Dioxide; D000661:Amphetamine