Cyclic AMP-dependent protein kinase content of murine splenic T and B lymphocytes and non-lymphoid tissues.
Cyclic AMP-dependent protein kinase activity has been measured in DEAE-cellulose elution profiles of highly enriched murine splenic T and B Lymphocytes. B Lymphocytes were found to contain about 10% of the amount of enzyme activity associated with T lymphocytes and several non-lymphoid tissues. Cyclic AMP-independent casein kinase activities were equivalent in T and B lymphocytes. Lymphocytes contained predominantly type I isozyme as opposed to several non-lymphoid tissues which all contained predominantly the type II form.
D000818:Animals; D001402:B-Lymphocytes / Q000201:enzymology*; D000242:Cyclic AMP / Q000494:pharmacology; D007527:Isoenzymes / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D011494:Protein Kinases / Q000378:metabolism*; D013154:Spleen / Q000201:enzymology; D013601:T-Lymphocytes / Q000201:enzymology*; D014018:Tissue Distribution
D007527:Isoenzymes; D000242:Cyclic AMP; D011494:Protein Kinases