[Ion channels, induced by amphotericin B introduced unilaterally into lipid bilayers].
Single ionic channels of approximately 10 pS in magnitude and approximately 100 ms duration (in 2 M KCl solution) were recorded when amphotericin B (AB) was added to one side of a lipid bilayer. Using blocking ions it has been shown that these channels are asymmetrical half-pores (similar to those postulated by Marty and Finkelstein) which are capable of forming long-living symmetrical pores if AB is added to both sides of the membrane.
D000666:Amphotericin B; D007473:Ion Channels / Q000378:metabolism; D007700:Kinetics; D008051:Lipid Bilayers; D008954:Models, Biological
D007473:Ion Channels; D008051:Lipid Bilayers; D000666:Amphotericin B
Ionnye kanaly, indutsiruemye amfoteritsinom B pri ego odnostoronnem vvedenii v lipidnyĭ bisloĭ.