title: mlt Mutants of polyoma virus.
abstract: New mlt deletion mutants of polyoma virus were isolated, and their abilities to produce a lytic response in mouse cells or to transform rat cells were assessed. Their properties were analyzed in terms of the sequences deleted and their effects upon the structure and functions of the viral middle and large T-antigens.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D000957:Antigens, Viral, Tumor; D001483:Base Sequence; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured; D051379:Mice; D009154:Mutation; D011120:Polyomavirus / Q000235:genetics* / Q000276:immunology; D051381:Rats
chemical_list: D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor