title: [25-hydroxy-vitamin-D in serum of newborns and infants during continuous oral vitamin D treatment (author's transl)].
abstract: Using the Haddad modified method, 25-OH-D were measured in the blood of the umbilical cord of 29 infants and in peripheral serum after 6 weeks. 16 infants were given a daily dosage of 1000 I. E., 13 infants 500 I. E. vitamin D against rickets. Further they were fed with an adapted milk containing 400 I. E. vitamin D/1. The mean cord serum values were 13 and 15 ng/ml. After treatment with 1000 I. E., 25-OH-D values around 54 ng/ml were measured after 6 weeks and under 500 I. E. daily, values of 37 ng/ml, respectively. Treatment using a dosage of 500 I. E. vitamin D combined with feeding with vitamin D fortified milk seems adequate, to prevent vitamin D depletion.
mesh_terms: D015652:25-Hydroxyvitamin D 2; D002762:Cholecalciferol / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004872:Ergocalciferols / Q000031:analogs & derivatives* / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood*; D012279:Rickets / Q000097:blood / Q000517:prevention & control*; D014808:Vitamin D Deficiency / Q000097:blood* / Q000517:prevention & control
chemical_list: D004872:Ergocalciferols; D002762:Cholecalciferol; D015652:25-Hydroxyvitamin D 2
vernacular_title: 25-Hydroxy-Vitamin-D im Serum von Neugeborenen und Säuglingen unter kontinuierlicher oraler Vitamin-D-Prophylaxe.