title: [Glioblastoma multiforme developing after a gunshot injury of the brain (author's transl)].
abstract: We report the case of a 28-year-old male who suffered a frontal penetrating gunshot injury with subsequent bifrontal brain abscess and subdural empyema, and five years later developed a large bifrontal tumour at the precise site of the meningo-cerebral scar and posttraumatic defect. Histological examination showed a glioblastoma multiforme adjacent to the dural scar and, in addition, old suture material was found within the glioma tissue. In spite of combined radiation and polychemotherapy the patient died eleven months after partial tumour resection. The temporal and local association of missile injury with subsequent recurred abscess and scar formation and the malignant glioma is highly suggestive of a causal relationship between trauma and the development of a brain tumour.
mesh_terms: D000328:Adult; D001922:Brain Abscess / Q000150:complications; D001930:Brain Injuries / Q000150:complications*; D001932:Brain Neoplasms / Q000209:etiology*; D005909:Glioblastoma / Q000209:etiology*; D006801:Humans; D008297:Male; D013537:Sutures; D013997:Time Factors; D014948:Wounds, Gunshot / Q000150:complications*
vernacular_title: Glioblastoma multiforme nach Kopfschuss.