The effect of elbow joint afferent discharge on transmission in forelimb flexion reflex pathways to biceps and triceps brachii in decerebrate cats.
The present experiments were performed to investigate the influence of elbow joint afferent discharge on the excitability of reflex arcs mediating flexion withdrawal and crossed extensor reflexes in the forelimb muscles of decerebrate cats. The excitability of flexion withdrawal and crossed extensor reflexes in forelimb muscles was shown to be modulated by elbow joint position. Flexion withdrawal reflexes were most easily elicited when the elbow was extended and crossed extensor reflexes were most easily elicited when the elbow was flexed. This modulation of transmission was not confined to reflex pathways projecting to muscles acting at the elbow but also included pathways to muscles acting at the wrist and shoulder in addition to muscles in the contralateral forelimb. The changing excitability of reflex pathways caused by elbow movement was unaltered by degloving the skin covering the joint and tenotomy of the medial head of triceps and the long head of biceps. However, modulation of reflex excitability by joint movement was totally abolished by local anaesthesia of the joint in an otherwise intact limb. Thus, the present experiments indicate that transmission in forelimb flexion reflex pathways can be powerfully influenced by elbow joint afferent discharge.
D000818:Animals; D002415:Cats; D002490:Central Nervous System / Q000502:physiology*; D003655:Decerebrate State / Q000503:physiopathology*; D004551:Elbow Joint / Q000294:innervation*; D005246:Feedback; D009046:Motor Neurons / Q000502:physiology; D009132:Muscles / Q000294:innervation*; D009434:Neural Pathways / Q000502:physiology; D011187:Posture; D012018:Reflex / Q000502:physiology*; D009435:Synaptic Transmission