Malakoplakia of testis.
Two cases of malakoplakia of the testis are reported. Ultrastructural studies were performed in both cases and confirmed the histiocytic nature of the large cells seen in this granulomatous process. Characteristic Michaelis-Gutmann bodies are identified in those macrophages and seem to originate from altered lysosomes. From these observations and a review of the literature, the possible physiopathogenesis of the disease is summarized, and comments are made on the treatment of malakoplakia.
D000328:Adult; D000368:Aged; D006644:Histiocytes / Q000166:cytology / Q000473:pathology; D006801:Humans; D002479:Inclusion Bodies; D008287:Malacoplakia / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013733:Testicular Diseases / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013737:Testis / Q000601:surgery