Familial gliomas: report of four families, with chromosome studies.
Four families having multiple family members with cerebral gliomas are presented. Genetic studies were done in some, but no chromosomal abnormalities were found in this group of patients or their families. The authors recommend that careful attention be given to the family history of all glioma patients and that more extensive genetic studies be done. The formation of a registry to report cases of familial gliomas is also suggested.
D000293:Adolescent; D001254:Astrocytoma / Q000235:genetics* / Q000473:pathology; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000235:genetics* / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000235:genetics / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002874:Chromosome Mapping; D005909:Glioblastoma / Q000235:genetics* / Q000473:pathology; D005910:Glioma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000235:genetics / Q000473:pathology; D008875:Middle Aged; D014057:Tomography, X-Ray Computed