title: Culture-proven cytomegalovirus retinitis in a homosexual man with the acquired immunodeficiency syndrome.
abstract: A 35-year-old homosexual man with cytomegalovirus viremia developed retinitis. He also had a new syndrome consisting of a persistent T-lymphocyte deficit, pneumocystis pneumonia, recurrent Candida albicans esophagitis, skin ulcerations caused by herpes simplex virus, Type 2, disseminated Mycobacterium avium-intracellulare infection, and molluscum contagiosum. Histopathologic examination revealed bilateral necrotizing retinitis with virions in retinal, choroidal, and optic nerve tissues. Postmortem cultures of retina and vitreous were positive for cytomegalovirus.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D002177:Candidiasis / Q000150:complications; D003586:Cytomegalovirus Infections / Q000150:complications*; D004941:Esophagitis / Q000150:complications; D006561:Herpes Simplex / Q000150:complications; D006716:Homosexuality; D006801:Humans; D008297:Male; D009164:Mycobacterium Infections / Q000150:complications; D011020:Pneumonia, Pneumocystis / Q000150:complications; D012173:Retinitis / Q000175:diagnosis / Q000382:microbiology*; D013601:T-Lymphocytes / Q000276:immunology