Aflatoxins, B1, B2, G1, G2 in primary liver cell carcinoma.
Aflatoxin B1, B2, G1, G2 levels were determined in sera of 20 patients with primary liver cell carcinoma (CC). Values of B1 above 0.15 microgram/ml were obtained in sera of three patients. Hepatitis B surface antigen (HBsAg) was detected in only 35% of patients. 50-90% of serum levels were cleared in 24 h in three patients studied. Although it is inconclusive as to the carcinogenic potential of aflatoxins in adult man, foodstuffs should be protected from excessive aflatoxin contamination.
D000328:Adult; D016604:Aflatoxin B1; D000348:Aflatoxins / Q000097:blood* / Q000633:toxicity; D006528:Carcinoma, Hepatocellular / Q000097:blood*; D005260:Female; D006515:Hepatitis B virus / Q000472:pathogenicity; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood* / Q000209:etiology; D008297:Male
D000348:Aflatoxins; C027955:aflatoxin G1; D016604:Aflatoxin B1