title: Stannous ion quantitation in 99mTc-radiopharmaceutical kits.
abstract: A simple and inexpensive method for the estimation of stannous ion, Sn (II), in radiopharmaceutical kits is described. The method used is a potentiometric titration of Sn (II) in 1 N HCI medium, using potassium iodate as the oxidizing agent in an atmosphere of nitrogen. The apparatus includes pH meter, a platinum electrode, and a simple titration cell. Several commonly used radiopharmaceutical kits were analyzed for their Sn (II) content using this method. These studies indicate that the procedure can be used, as a routine quantitative test for the Sn (II) content of various 99mTc-labeled radiopharmaceuticals.
mesh_terms: D006863:Hydrogen-Ion Concentration; D011199:Potentiometry; D011933:Reagent Kits, Diagnostic; D013670:Sodium Pertechnetate Tc 99m; D013667:Technetium; D014001:Tin
chemical_list: D011933:Reagent Kits, Diagnostic; D013667:Technetium; D014001:Tin; D013670:Sodium Pertechnetate Tc 99m