In vitro evaluation of B-lymphocyte function in turkeys infected with hemorrhagic enteritis virus.
Studies were conducted on B-lymphocyte function in turkeys infected with hemorrhagic enteritis (HE) virus. Hemolytic plaque-forming technique was used to detect antibody-forming cells in turkeys. The plaque-forming cell responses in HE virus-infected and noninfected controls were compared. Results of this study indicated a decreased capability of HE virus-infected turkeys to produce antibodies to sheep RBC. The greatest inhibition of antibody-forming cell production was seen in the turkeys 19 days after exposure to the virus. However, after this period, the turkeys gradually recovered their immunocompetence to sheep RBC.
D000257:Adenoviridae Infections / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D004751:Enteritis / Q000276:immunology / Q000662:veterinary*; D004912:Erythrocytes / Q000276:immunology; D007108:Immune Tolerance; D066298:In Vitro Techniques; D011201:Poultry Diseases / Q000276:immunology*; D012756:Sheep; D014422:Turkeys / Q000276:immunology*; D010948:Viral Plaque Assay / Q000662:veterinary