Serological markers of hepatitis A and B virus infection in university students.
Serological markers of hepatitis A and B virus infection were determined by radioimmunoassay in 162 university students. Antibody to hepatitis B e antigen (anti-HBe) was demonstrated in 11 of 15 students positive for both antibody to hepatitis B e antigen (HBsAg) and antibody to hepatitis B core antigen (anti-HBc). The presence of anti-HBc alone seemed to denote previous hepatitis B virus infection. Antibody to hepatitis A virus was demonstrated only in 3%. Study of 23 stored HBsAg-positive sera showed high titer anti-HBc significantly more frequently in sera positive for anti-HBe than in sera positive for hepatitis B e antigen. Incidence of hepatitis B e antigen was significantly higher in male students with HBsAg, and that of anti-HBe in female students.
D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D006446:Hemoglobin E; D006506:Hepatitis A / Q000175:diagnosis*; D006509:Hepatitis B / Q000175:diagnosis*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006511:Hepatitis B Antigens / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006513:Hepatitis B e Antigens / Q000032:analysis; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D008297:Male; D013334:Students
D000914:Antibodies, Viral; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D006446:Hemoglobin E