Restriction fragment analysis for differentiation of indistinguishable temperate coliphages.
DNA of lambda and seven related phages was digested with restriction endonuclease, EcoRI. Seven different fragment patterns were observed, only two of the eight phages showing identical profiles. Restriction enzyme fragment analysis is thus shown to be a sensitive tool for the differentiation of biologically indistinguishable phages.
D010582:Bacteriophage lambda / Q000032:analysis / Q000145:classification*; D001483:Base Sequence; D003090:Coliphages / Q000032:analysis / Q000145:classification*; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis*; D015246:Deoxyribonuclease EcoRI
D004279:DNA, Viral; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI