title: Effect of polybrominated biphenyls (PBB) on developmental abilities in young children.
abstract: Eighteen children, ages 4 to 6 years, with known exposure to polybrominated biphenyls (PBB) in utero and/or through breast milk were administered developmental tests. These same children had exhibited low scores on a partial developmental assessment two years earlier. Current results were compared to normative test data. Findings showed: 1) PBB cohort children are within the normal range in all areas assessed; 2) An inverse relationship is noted between PBB fat level and scores on some developmental tasks. The importance of this finding for later development is unclear and, thus will bear future monitoring.
mesh_terms: D001713:Biphenyl Compounds / Q000494:pharmacology*; D002648:Child; D002657:Child Development / Q000187:drug effects*; D002675:Child, Preschool; D003071:Cognition / Q000187:drug effects; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D008824:Michigan; D009048:Motor Skills / Q000187:drug effects; D011075:Polybrominated Biphenyls / Q000494:pharmacology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
chemical_list: D001713:Biphenyl Compounds; D011075:Polybrominated Biphenyls