Sex differences in alpha-adrenergic receptors in the rat brain.
[3H]Dihydroergocryptine ([3H]DHE) binding to several brain regions was studied in male and female rats, the latter in two different endocrinological states (estrous and diestrous-1). males showed higher [3H]DHE binding than females in hypothalamus, hippocampus and olfactory bulb, while females showed higher levels than males in spinal cord and visual cortex. In addition, intra-sex (that is, estrous versus diestrous-1) differences were detected in the cervico-thoracic spinal cord and cerebellum. Diestrous females presented higher values in both regions.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D004088:Dihydroergotoxine / Q000378:metabolism; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism*; D012737:Sex Factors; D013116:Spinal Cord / Q000378:metabolism; D014018:Tissue Distribution
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D004088:Dihydroergotoxine