title: Regulation of fatty acid composition of Cl. perfringens type A cells by hydrogen and hydroxyl ions.
abstract: The composition of the fatty acid profiles of Cl. perfringens type A, grown on media with initial pH values from 5.5 to 9.0, was determined by the method of gas-liquid chromatography. The fatty acid profiles are stabilized in 18- to 24-h cultures. Hydrogen ions stimulate the synthesis of cyclopropane carboxylic fatty acids and "desaturase" activity; hydroxyl ions inhibit these processes. The content of saturated fatty acids in the bacteria is regulated by the initial acid-alkaline conditions of the medium. An increase in biomass accumulation under the influence of hydroxyl ions is coupled with a decrease in the energy supply of the bacteria. Possible mechanisms of the development of resistance to hydrogen and hydroxyl ions during the cultivation of Clostridia on a period growth medium are discussed.
mesh_terms: D000838:Anions; D002849:Chromatography, Gas; D003016:Clostridium perfringens / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D006878:Hydroxides / Q000494:pharmacology; D017665:Hydroxyl Radical; D007700:Kinetics
chemical_list: D000838:Anions; D005227:Fatty Acids; D006878:Hydroxides; D017665:Hydroxyl Radical