title: Adenoma sebaceum of Pringle: a clinicopathologic review, with a discussion of related pathologic entities.
abstract: "Adenoma sebaceum of Pringle" (ASP) is a misnomer. The tumor is not an adenoma and is not derived from sebaceous glands. The lesion is characterized by dermal fibrosis and associated vascular proliferation and dilatation. Changes in contiguous sebaceous glands and other adnexal structures are merely secondary. Thus, "angiofibroma" would be a more appropriate name. The histologic changes in ASP (and in related pathologic lesions) suggest that it is a hamartoma rather than a true neoplasm. However, the embryologic tissue of its origin is not definitively known.
mesh_terms: D000236:Adenoma / Q000473:pathology; D005153:Facial Neoplasms / Q000473:pathology; D005385:Fingers / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010412:Penile Neoplasms / Q000473:pathology; D012626:Sebaceous Gland Neoplasms / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*