Effects of a few xenobiots on three phosphatases of Saccobranchus fossilis and the role of ascorbic acid in their toxicity.
The effects of 0.0021, 0.00126 and 0.00063 mg thiotox per liter and 5.18, 3.11 and 1.56 malathion per liter (1/3, 1/5, and 1/10 fractions of 96-h LC50) on acid, alkaline and glucose-6-phosphatases in liver, brain and gills of Saccobranchus fossilis were studied after 30 days exposure with or without ascorbic acid. These enzyme activities were altered by these pesticides, but lesser alterations were observed when ascorbic acid was given.
D000135:Acid Phosphatase / Q000037:antagonists & inhibitors*; D000469:Alkaline Phosphatase / Q000037:antagonists & inhibitors*; D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D004726:Endosulfan / Q000633:toxicity*; D005399:Fishes / Q000378:metabolism*; D005952:Glucose-6-Phosphatase / Q000037:antagonists & inhibitors*; D008294:Malathion / Q000633:toxicity*; D010575:Pesticides / Q000633:toxicity*
D010575:Pesticides; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005952:Glucose-6-Phosphatase; D004726:Endosulfan; D001205:Ascorbic Acid; D008294:Malathion