Lysosomal localisation of parallel tubular arrays in chronic lymphocytic leukaemia of T cell origin: an ultrastructural cytochemical study.
An ultrastructural cytochemical study of lysosomal acid phosphatase was performed on leukemic cells in a case of chronic lymphocytic leukaemia of T cell origin (T-CLL). The cells showed inclusion bodies known as parallel tubular arrays, which often lay within acid phosphatase-positive, membrane-bound spaces. This suggests their lysosomal location.
D000135:Acid Phosphatase / Q000378:metabolism; D000368:Aged; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007945:Leukemia, Lymphoid / Q000201:enzymology / Q000473:pathology*; D008247:Lysosomes / Q000201:enzymology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D013601:T-Lymphocytes / Q000201:enzymology / Q000648:ultrastructure
D000135:Acid Phosphatase