title: Local recurrence of breast cancer: its significance in relation to breast reconstruction.
abstract: Questions regarding local recurrences are a major concern in considering mastectomy patients for breast reconstruction. A critical analysis of the literature on local recurrences indirectly provides answers to several of these concerns. Local recurrence is a relatively predictable event, and is uncommon in those with a favourable breast cancer. Its presence reflects concurrent systemic disease which is usually lethal within a short time. Concern over subsequent local recurrences should not be a contraindication to breast reconstruction in selected patients.
mesh_terms: D001940:Breast / Q000601:surgery*; D001943:Breast Neoplasms / Q000150:complications / Q000601:surgery*; D002278:Carcinoma in Situ / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000209:etiology; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000601:surgery; D009367:Neoplasm Staging; D011336:Probability; D011956:Receptors, Cell Surface / Q000096:biosynthesis; D013518:Surgery, Plastic; D013997:Time Factors
chemical_list: D011956:Receptors, Cell Surface