[Effect of preparations altering cAMP metabolism on the bioelectrogenesis of the skeletal muscles].
In the frog isolated m. sartorius, microelectrode technique and in vivo TV microscopy differentiating bioelectrical phenomena in separate fibers of different groups (dark, light, intermediate), revealed that the drugs altering cAMF exchange (adrenaline, caffeine, imidazole) and used in concentration 10(-5) M, affect to different extents the resting potential and the AP. The effect of the drugs is more obvious in respect to excitatory potential. Mechanism of this phenomenon is discussed.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004837:Epinephrine / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology; D066298:In Vitro Techniques; D007552:Isotonic Solutions; D008564:Membrane Potentials / Q000187:drug effects; D009132:Muscles / Q000187:drug effects* / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology; D000077331:Ringer's Solution; D013997:Time Factors
D007093:Imidazoles; D007552:Isotonic Solutions; D000077331:Ringer's Solution; D011433:Propranolol; D000242:Cyclic AMP; D004837:Epinephrine
Vliianie preparatov, izmeniaiushchikh obmen tsAMF, na bioélektrogenez skeletnykh myshts.