CSF beta-endorphin-immunoreactivity in normal, schizophrenic, depressed, manic and anorexic subjects.
beta-Endorphin immunoreactivity was measured in cerebrospinal fluid of 75 medication-free subjects: normal, depressed, schizophrenic, and anorexic. No significant differences in beta-endorphin immunoreactivity were found. Affinity extraction chromatography revealed beta-lipotropin and beta-endorphin, but no apparent precursors.
D000293:Adolescent; D000328:Adult; D000341:Affective Disorders, Psychotic / Q000134:cerebrospinal fluid*; D000368:Aged; D000856:Anorexia Nervosa / Q000134:cerebrospinal fluid*; D001714:Bipolar Disorder / Q000134:cerebrospinal fluid; D003866:Depressive Disorder / Q000134:cerebrospinal fluid; D004723:Endorphins / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012559:Schizophrenia / Q000134:cerebrospinal fluid*; D001615:beta-Endorphin
D004723:Endorphins; D001615:beta-Endorphin