title: [Bilateral lung irradiation as adjuvant therapy in osteogenic sarcoma ].
abstract: Bilateral lung irradiation as well as chemotherapy are still controversial in the "prevention" of pulmonary metastases from osteosarcomas. This paper presents theoretical and experimental evidence in support of such an irradiation. Doses which can be tolerated by the normal lung are recalled. Data from clinical experience is analyzed and the optimal modalities of irradiation are described. Confirmation of the presumptive effectiveness of radiation therapy can be obtained only through controlled trials such as the one which is ongoing at the EORTC.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001859:Bone Neoplasms / Q000532:radiotherapy; D002648:Child; D002986:Clinical Trials as Topic; D004285:Dogs; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000517:prevention & control* / Q000556:secondary; D008297:Male; D012516:Osteosarcoma / Q000517:prevention & control / Q000532:radiotherapy* / Q000556:secondary; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage
vernacular_title: Place de l'irradiation pulmonaire bilatérale dans le traitement adjuvant des sarcomes ostéogènes.