Neurohormonal peptides and argyrophil cells in an androblastoma of the ovary.
An ovarian epithelial tumour is described with a compound histological structure containing features of an androblastoma with well differentiated Sertoli-Leydig cell structures and features resembling a carcinoid tumour. Scattered argyrophil cells were demonstrated in both components of the tumour. Neurohormonal peptides were found immunocytochemically in a minor fraction of the argyrophil cells. These included pancreatic polypeptide (PP), glucagon/enteroglucagon and enkephalin. These findings indicate a high degree of multipotentiality of the progenitor cells of the neoplasm.
D005260:Female; D006651:Histocytochemistry; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007985:Leydig Cells / Q000473:pathology; D008297:Male; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D012708:Sertoli Cells / Q000473:pathology; D018310:Sertoli-Leydig Cell Tumor / Q000378:metabolism / Q000473:pathology*; D012835:Silver Nitrate / Q000378:metabolism
D006728:Hormones; D012835:Silver Nitrate