[Opiate receptors of peripheral blood lymphocytes (effect of morphine and naloxone on human T-lymphocytes)].
Using the method of spontaneous rosette formation the authors studied the effects of morphine and naloxone (a specific morphine antagonist) on T-lymphocytes of man peripheral blood. Treatment of the lymphocytes with morphine led to a diminution of the number of rosette-forming cells. Naloxone did not influence the rosette formation process, but eliminated the specific effect of morphine. The opiate receptors on the thymus-dependent lymphocytes may be an instrument of hormonal regulation of cell interaction processes in individual lymphocyte populations.
D006801:Humans; D008214:Lymphocytes / Q000032:analysis; D009020:Morphine / Q000494:pharmacology*; D009270:Naloxone / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000032:analysis*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects*
D011957:Receptors, Opioid; D009270:Naloxone; D009020:Morphine
Izuchenie opiatnykh retseptorov limfotsitov perifericheskoí krovi (vliianie morfina i naloksona na T-limfotsity cheloveka).