Relationships between morphology and viral etiology in mammary tumors of BALB/cfC3H and BALB/cfRIII mice.
The morphologic pattern of mammary tumors induced by milk-transmitted C3H and RIII murine mammary tumor viruses (MuMTVs) in BALB/c hosts infected by foster nursing were investigated further an compared taking into account several tumor and host variables. Comparison of BALB/cfC3H and BALB/cfRIII mammary tumors under identical tumor and host conditions showed highly significant differences in subgross morphology and histologic structure. Differences in cytology were also observed. Data suggest that mammary tumor morphology in high cancer strain mice is controlled by the causative MuMTV.
D000818:Animals; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000209:etiology / Q000473:pathology*; D008324:Mammary Tumor Virus, Mouse / Q000472:pathogenicity*; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H