[Age changes of structural state of synaptic membranes of brain].
In the brain synaptic membranes from old rats (24-26 months) in comparison with the mature ones (6-7 months) an increase was shown in disintegration rate with DDS Na, mobility of 5-, 16-doxyl-stearate spin probes and in thermosensitivity of acetylcholinesterase. The total number of SH-groups decreased. While protein composition remained constant lysophosphatidylcholine and saturated fatty acid content in old animals increased. The age-dependent structural rearrangement of synaptic membranes is suggested.
D000375:Aging; D000818:Animals; D001921:Brain / Q000254:growth & development*; D004578:Electron Spin Resonance Spectroscopy; D051381:Rats; D012967:Sodium Dodecyl Sulfate; D013570:Synaptic Membranes / Q000502:physiology*; D013696:Temperature
D012967:Sodium Dodecyl Sulfate
Vozrastnye izmeneniia strukutrnogo sostoianiia sinapticheskikh membran mozga.