[Prostaglandins and cancer of the breast (author's transl)].
To investigate the basic characteristics of PG synthesis by human breast tumors, we have examined the relationship that could exist between the PG production and the morphological, cellular and biochemical characteristics which actually constitute the criteria of diagnosis and prognosis of human breast cancer. The results that are discussed here show that raised PG production would seem to be a marker for neoplastic cells that are capable of leading to metastatic growths in the lymph nodes. The raised production of PG can be a marker of a cell population that has the capacity to be autonomous and which possesses a high potential for metastasis.
D001943:Breast Neoplasms / Q000378:metabolism* / Q000648:ultrastructure; D002448:Cell Adhesion; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D011453:Prostaglandins / Q000096:biosynthesis*; D011956:Receptors, Cell Surface / Q000378:metabolism
D011453:Prostaglandins; D011956:Receptors, Cell Surface; D011451:Prostaglandin-Endoperoxide Synthases
Prostaglandines et cancer du sein.