[Evaluation of the treatment of symptomatic urinary tract infection with a single dose of antibiotics or bicarbonate].
68 women with acute, uncomplicated urinary tract infection confirmed bacteriologically were randomized to receive either a single oral dose of cotrimoxazole, a single oral dose of amoxycillin, or an oral dose of Na-bicarbonate. Results comparable to previous reports were obtained with the cotrimoxazole regimen. On the other hand, the efficacy of single-dose amoxycillin appeared to be inferior. It is possible that pharmacocinetic differences influence the efficacy of these drugs.
D000328:Adult; D000553:Ambulatory Care; D000658:Amoxicillin / Q000627:therapeutic use; D001639:Bicarbonates / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008875:Middle Aged; D010919:Placebos; D011897:Random Allocation; D017693:Sodium Bicarbonate; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy*
D001639:Bicarbonates; D010919:Placebos; D000658:Amoxicillin; D017693:Sodium Bicarbonate; D014295:Trimethoprim; D013420:Sulfamethoxazole
Evaluation du traitement de l'infection urinaire symptomatique par dose unique d'antibiotiques ou par bicarbonate.