[Effect of benz(a)pyrene and its non-carcinogenic analog 1,2-benzopyrene on the Na, K-ATPase activity of homogenates of different mouse organs and rat heart membrane preparations].
The carcinogenic agent benz(a)pyrene inhibits Na, K-ATPase activity of organ homogenates where it is capable of inducing tumors. It causes no significant changes in target organ homogenates.
D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013270:Stomach / Q000201:enzymology
D001580:Benzopyrenes; D001564:Benzo(a)pyrene; C026487:benzo(e)pyrene; D000254:Sodium-Potassium-Exchanging ATPase
Vliianie benz(a)pirena i ego nekantserogennogo analoga 1,2-benzopirena na Na, K-ATF-aznuiu aktivnost' gomogenatov razlichnykh organov myshi i membrannogo preparata iz serdtsa krysy.