title: [In vitro maturation of mammalian oocytes. I. The hormonal regulation of maturation].
abstract: A review of the data on in vitro induction of meiotic maturation in cultured follicles and oocytes in mammals. The data are given on cyclic AMP accumulation, steroidogenesis and glycolysis in preovulatory follicles and on the effect of the substances synthesized, as well as the follicular constituents (cumulus and granulosa cells and follicular fluid) on oocyte maturation. Hypotheses concerning the mechanism of gonadotropin - induced mammalian oocyte maturation are discussed.
mesh_terms: D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D006224:Cricetinae; D000242:Cyclic AMP / Q000502:physiology; D004971:Estrus; D005260:Female; D005640:Follicle Stimulating Hormone / Q000502:physiology; D006065:Gonadotropins, Pituitary / Q000494:pharmacology / Q000502:physiology*; D006107:Granulosa Cells / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D007986:Luteinizing Hormone / Q000502:physiology; D051379:Mice; D009865:Oocytes / Q000187:drug effects / Q000254:growth & development*; D006080:Ovarian Follicle / Q000187:drug effects / Q000502:physiology; D010063:Ovum / Q000254:growth & development*; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D013256:Steroids / Q000494:pharmacology
chemical_list: D006065:Gonadotropins, Pituitary; D013256:Steroids; D003994:Bucladesine; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D000242:Cyclic AMP
vernacular_title: Sozrevanie in vitro ootsitov mlekopitaiushchikh zhivotnykh. I. Gormonal'naia reguliatsiia sozrevaniia.