Sequence-specific contacts between the RNA polymerase of vesicular stomatitis virus and the leader RNA gene.
Methylation-protection studies with nucleocapsids from vesicular stomatitis virus indicate that the viral polymerase (L and NS proteins) contacts the genomic RNA template in the middle of the leader gene, 16-30 nucleotides from the 3' terminus. The data suggest that the NS protein binds to the sequence (formula, see text) and may function as an initiator protein for transcription.
D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D006224:Cricetinae; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D005814:Genes, Viral; D007668:Kidney; D008745:Methylation; D012367:RNA, Viral / Q000235:genetics*; D014721:Vesicular stomatitis Indiana virus / Q000235:genetics*
D012367:RNA, Viral; D012321:DNA-Directed RNA Polymerases