title: Growth and persistence of polyoma early region deletion mutants in mice.
abstract: Replication of early region deletion mutations in polyoma in the kidneys of mice was in most cases reduced by 10- to 10,000-fold, as compared with wild-type polyoma, and the mutants failed to produce the persistent infection observed with wild-type polyoma.
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000235:genetics; D000956:Antigens, Viral / Q000235:genetics; D000957:Antigens, Viral, Tumor; D005814:Genes, Viral; D007668:Kidney / Q000382:microbiology*; D051379:Mice; D009154:Mutation; D011120:Polyomavirus / Q000235:genetics* / Q000254:growth & development; D014412:Tumor Virus Infections / Q000382:microbiology*; D014779:Virus Replication
chemical_list: D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor