Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin-neurophysin II precursor.
The sequence of a cDNA encoding the nonapeptide arginine vasopressin (AVP) and its carrier protein, neurophysin II (NpII) from bovine hypothalamus, proves that the 166-amino acid precursor molecule contains a signal peptide of 19 amino acids followed directly by AVP connected to NpII by a Gly-Lys-Arg sequence. The carboxy-terminal region of the precursor contains a naturally occurring glycopolypeptide of 39 amino acids which is separated from NpII by a single arginine residue.
D000595:Amino Acid Sequence; D000818:Animals; D001127:Arginine Vasopressin / Q000235:genetics*; D001483:Base Sequence; D002417:Cattle; D003001:Cloning, Molecular; D004247:DNA; D004262:DNA Restriction Enzymes; D007031:Hypothalamus / Q000378:metabolism; D008970:Molecular Weight; D009481:Neurophysins / Q000235:genetics*; D011498:Protein Precursors / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics
D009481:Neurophysins; D011498:Protein Precursors; D012333:RNA, Messenger; D001127:Arginine Vasopressin; D004247:DNA; D004262:DNA Restriction Enzymes