Actin distribution and synthesis in human fibroblasts infected by cytomegalovirus.
"Early functions" of human cytomegalovirus were found to induce a loss of microfilaments as revealed by indirect immunofluorescence and by the use of fluorescent phalloidin. Actin synthesis in infected cultures, on the other hand, appeared to be largely unchanged as estimated from the specific radioactivity of cytoplasmic actin.
D000199:Actins / Q000096:biosynthesis*; D002472:Cell Transformation, Viral; D003587:Cytomegalovirus / Q000502:physiology; D003586:Cytomegalovirus Infections / Q000378:metabolism* / Q000473:pathology; D003599:Cytoskeleton / Q000648:ultrastructure*; D006801:Humans
D000199:Actins