Effects of propylthiouracil on MHV-3 virus mouse hepatitis.
A study was undertaken to observe the effect of propylthiouracil (PTU) on MHV-3 virus mouse hepatitis. PTU-treatment adversely influenced the course of the hepatitis. This effect was reflected by a significantly higher mortality rate, in spite of the absence of any significant difference of the plasma transaminase activity increase and of the liver virus content.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D006524:Hepatitis, Viral, Animal / Q000201:enzymology / Q000382:microbiology / Q000503:physiopathology*; D008297:Male; D051379:Mice; D006517:Murine hepatitis virus; D011441:Propylthiouracil / Q000494:pharmacology*; D013997:Time Factors
D011441:Propylthiouracil; D000410:Alanine Transaminase