[Organ-specific ultrastructural cellular signs of cancerous breast tumors].
The ultrastructural analysis of 40 cases of mammary carcinomas revealed two groups of cells: with ultrastructural organ specific features (differentiated cells) and without them (undifferentiated cells). Intracytoplasmic lumens, secretory granules (lipid, protein, and mixed lipid-protein), and myoepithelial cells are the main organ specific features of mammary carcinomas. The histospecific features showing the epithelial origin of the tumor cells include cell-to-cell contacts, ductules, intercytoplasmic lumens with microvilli, and fragments of basal lamina. These ultrastructural features of mammary carcinomas can facilitate the differential diagnosis of tumors of this organ.
D000230:Adenocarcinoma / Q000648:ultrastructure; D002288:Adenocarcinoma, Mucinous / Q000648:ultrastructure; D001940:Breast / Q000648:ultrastructure*; D001943:Breast Neoplasms / Q000648:ultrastructure*; D002277:Carcinoma / Q000648:ultrastructure; D002278:Carcinoma in Situ / Q000648:ultrastructure; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009928:Organ Specificity
Ul'trastrukturnye organospetsificheskie prinaki kletok rakovykh opukholeĭ molochnoí zhelezy.