Epstein-Barr virus in nasopharyngeal and salivary gland carcinomas of Greenland Eskimoes.
Biopsy specimens from nasopharyngeal carcinomas (NPC) or salivary-gland carcinomas (SGC) in Greenland Eskimoes were examined for the presence of Epstein-Barr virus (EBV) DNA and sera from the patients were tested for EBV-specific antibody titres. Six out of 7 NPCs and one from an undifferentiated SGG were positive for EBV DNA. The EBV-specific antibody spectra and titres of the patients with NPC or undifferentiated SGG conformed to the results of earlier studies in other high-incidence areas.
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006116:Greenland; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D004930:Inuit; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000032:analysis / Q000276:immunology / Q000382:microbiology*; D012468:Salivary Gland Neoplasms / Q000032:analysis / Q000276:immunology / Q000382:microbiology*
D000914:Antibodies, Viral; D004279:DNA, Viral