title: Representation of mRNA sequences in normal and SV40 transformed human diploid fibroblasts.
abstract: The representation of mRNA sequences in normal and SV40-transformed WI-38 human diploid fibroblasts was examined. Variations in the hybridization of polysomal RNAs to 3H-labeled DNAs complementary to poly A+ mRNA of normal and SV40-transformed cells suggest differences in the mRNA populations. a comparison of the representation of histone RNA sequences of normal and SV40-transformed human diploid cells did not reveal significant differences.
mesh_terms: D001483:Base Sequence; D002460:Cell Line; D002472:Cell Transformation, Viral; D004247:DNA / Q000235:genetics; D004171:Diploidy; D005347:Fibroblasts; D006657:Histones / Q000235:genetics; D006801:Humans; D007700:Kinetics; D009693:Nucleic Acid Hybridization; D011061:Poly A / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D013539:Simian virus 40 / Q000235:genetics*
chemical_list: D006657:Histones; D012333:RNA, Messenger; D011061:Poly A; D004247:DNA