Mitochondrial formation of OH Radicals by an ubisemiquinone-dependent reaction an alternative pathway to the iron-catalysed Haber-Weiss cycle.
D000818:Animals; D000968:Antimycin A / Q000494:pharmacology; D002374:Catalase / Q000494:pharmacology; D003067:Coenzymes; D005609:Free Radicals; D006861:Hydrogen Peroxide / Q000378:metabolism; D006878:Hydroxides / Q000378:metabolism*; D017665:Hydroxyl Radical; D007501:Iron / Q000494:pharmacology*; D008929:Mitochondria, Heart / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats; D013804:Thenoyltrifluoroacetone / Q000494:pharmacology; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000494:pharmacology
D003067:Coenzymes; D005609:Free Radicals; D006878:Hydroxides; D014451:Ubiquinone; D013804:Thenoyltrifluoroacetone; D017665:Hydroxyl Radical; D000968:Antimycin A; D006861:Hydrogen Peroxide; D007501:Iron; D002374:Catalase; C024989:coenzyme Q10