Cytomegalovirus infection and kidney graft survival.
Among 123 cadaveric renal allograft recipients transplanted in the period 1971-79, there were 18 with no evidence of past or present cytomegalovirus infection, 34 with primary infection and 71 with reactivated infection. One-year actuarial graft survival was 68%, 32% and 54%, respectively. The reasons for the better graft prognosis in the group without CMV infection were less rejection and fewer infections.
D000328:Adult; D000914:Antibodies, Viral / Q000096:biosynthesis; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000209:etiology* / Q000276:immunology; D005260:Female; D006085:Graft Survival; D006801:Humans; D007668:Kidney / Q000276:immunology; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D014184:Transplantation, Homologous / Q000009:adverse effects*
D000914:Antibodies, Viral