Classification of beta-adrenoceptors in the microcirculation of skeletal muscle.
Nervous and humoral beta-adrenergic, postjunctional effects on microvascular resistance, on precapillary sphincter tone, and on transcapillary fluid exchange in cat skeletal muscle (Lundvall & Järhult 1974, 1976 a, Lundvall & Hillman 1978 a, b) were evaluated with regard to the beta 1- or beta 2-specificity of the adrenoceptors. Marked beta 2-dilator responses but no significant beta 1-effects were observed. The conclusion was therefore reached that neurogenic as well as humoral beta-adrenergic control of the microcirculation in skeletal muscle is exerted via activation of beta 2-adrenoceptors.
D000818:Animals; D002196:Capillaries / Q000502:physiology; D002415:Cats; D004558:Electric Stimulation; D006614:Hindlimb / Q000033:anatomy & histology; D008833:Microcirculation; D009132:Muscles / Q000098:blood supply*; D011941:Receptors, Adrenergic / Q000145:classification*; D011943:Receptors, Adrenergic, beta / Q000145:classification*; D013564:Sympathetic Nervous System / Q000502:physiology; D014655:Vascular Resistance; D014664:Vasodilation
D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta