title: Association of coronavirus infection with neonatal necrotizing enterocolitis.
abstract: From the clustered occurrence of numerous cases of necrotizing enterocolitis in newborns, it was possible to associate this disease significantly with infection due to coronavirus-like agents. Prematurity or low birth weight did not seem to affect the development of the disease, at least during the present epidemic. However, associated gas-producing bacteria could influence its severity and play a role in the appearance of pneumatosis. In many aspects the human disease is reminiscent of experimental necrotizing enterocolitis obtained by infection of germ-free newborn animals, as reported in the literature.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis / Q000276:immunology; D003332:Coronaviridae / Q000276:immunology* / Q000648:ultrastructure; D003333:Coronaviridae Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D004196:Disease Outbreaks / Q000453:epidemiology*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D005243:Feces / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D008854:Microscopy, Electron; D010297:Paris
chemical_list: D000914:Antibodies, Viral