[Lithium and diabetes insipidus. Theoretical and practical aspects. Therapeutic value of thiazide diuretics (author's transl)].
Lithium is increasingly prescribed by psychiatrists for manic-depressive psychosis and other affective disorders. Therefore, psychiatrists should be familiar with lithium-induced nephrogenic diabetes insipidus. Management of this condition is discussed. Thiazide diuretics have a paradoxical antidiuretic effect in lithium-induced diabetes insipidus. For this reason, it is no longer warranted to contraindicate concomitant use of lithium and thiazide diuretics.
D000328:Adult; D001581:Benzothiadiazines; D003919:Diabetes Insipidus / Q000139:chemically induced* / Q000503:physiopathology / Q000517:prevention & control; D004232:Diuretics; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D049993:Sodium Chloride Symporter Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D014667:Vasopressins / Q000097:blood
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D014667:Vasopressins; D008094:Lithium
Lithium et diabète insipide. Aspects théoriques et pratiques. Intérêt thérapeutique des thiazidiques.