The simultaneous determination of the products of estrogen 2- and 4-hydroxylase action; the use of high-performance liquid chromatography with electrochemical detection.
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D019363:Cytochrome P-450 CYP1A1; D004563:Electrochemistry; D004958:Estradiol / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism; D002393:Estrogens, Catechol / Q000378:metabolism*; D004970:Estrone / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D006894:Hydroxyestrones / Q000302:isolation & purification; D008099:Liver / Q000201:enzymology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013250:Steroid Hydroxylases / Q000378:metabolism*
D004967:Estrogens; D002393:Estrogens, Catechol; D006894:Hydroxyestrones; D004970:Estrone; D004958:Estradiol; C001390:2-hydroxyestradiol; C014036:4-hydroxyestradiol; D013250:Steroid Hydroxylases; D019363:Cytochrome P-450 CYP1A1; C020120:estrogen 2-hydroxylase