Border disease in a flock of Minnesota sheep.
A flock problem affecting newborn lambs on a Minnesota farm was investigated. The lambs had hairy fleece and rhythmic tremors, and were unthrifty. Histologic examination revealed hypomyelinization of the CNS and hypertrophy of primary follicles in the skin. A virus antigenically related to bovine viral diarrhea virus was isolated. Serum neutralization showed that a large number of flock ewes had much higher titers to bovine viral diarrhea virus than did control animals.
D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology; D005260:Female; D008910:Minnesota; D011247:Pregnancy; D012756:Sheep; D012757:Sheep Diseases / Q000151:congenital* / Q000382:microbiology / Q000473:pathology; D014036:Togaviridae Infections / Q000151:congenital / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*