The tolC locus of Escherichia coli affects the expression of three major outer membrane proteins.
tolC mutants, which are resistant to colicin E1 and also highly sensitive to detergents and dyes, were shown to lack the OmpF outer membrane protein. There was little effect on transcription as judged by the use of an ompF-lac operon fusion strain, and the tolC effect was probably due to a post-transcriptional effect. The NmpC protein and protein 2 were also tolC dependent.
D001425:Bacterial Outer Membrane Proteins; D003470:Culture Media; D004926:Escherichia coli / Q000235:genetics*; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D018272:Porins; D014158:Transcription, Genetic
D001425:Bacterial Outer Membrane Proteins; D003470:Culture Media; D008565:Membrane Proteins; D018272:Porins