Influence of chronic UV-light exposure on hepatic and cutaneous monooxygenases.
Hairless female Ng/-mice were irradiated by UV-light for 16 h daily over a period of 24 weeks. Monooxygenase activities were measured in liver and skin, and an induction of the aryl-hydrocarbon hydroxylase was detected in liver by both fluorometric and radiochemical methods, whereas no induction of this enzyme could be demonstrated in the skin.
D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000378:metabolism; D005260:Female; D051379:Mice; D008812:Mice, Hairless; D008861:Microsomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology* / Q000528:radiation effects; D010088:Oxidoreductases / Q000378:metabolism* / Q000528:radiation effects; D012867:Skin / Q000201:enzymology* / Q000528:radiation effects; D014466:Ultraviolet Rays
D001580:Benzopyrenes; D001564:Benzo(a)pyrene; D010088:Oxidoreductases