Electron optic aspects of a murine cytomegalovirus strain grown in R1 mouse kidney cell cultures.
The electron microscopic study of a mouse kidney cell line (R1) infected with a murine cytomegalovirus strain isolated from a micromammal captured in the area of endemic Balkan nephropathy demonstrated the presence of multiple types of virus particles, in different phases of replication. Nucleocapsids with a partially or almost totally empty centre were predominant. The small number of particles with an electron-dense core and double envelope points to a low yield of mature infectant particles.
D000818:Animals; D002213:Capsid; D002460:Cell Line; D002467:Cell Nucleus / Q000382:microbiology; D003587:Cytomegalovirus / Q000502:physiology / Q000648:ultrastructure*; D007668:Kidney; D051379:Mice; D008854:Microscopy, Electron; D014771:Virion / Q000648:ultrastructure; D014779:Virus Replication