[Change of current-voltage characteristics of amphotericin B ion channels accompanying its incorporation into the membrane].
Non-linearity of amphotericin B current-voltage characteristics is determined by means of the third harmonic generated in the membrane. A change of the sign of non-linearity is revealed during incorporation of antibiotic molecules into a membrane, i. e. the incorporation is not a simple increase of the number of similar ionic channels in the membrane.
D000666:Amphotericin B / Q000378:metabolism*; D002784:Cholesterol; D007473:Ion Channels / Q000502:physiology*; D007700:Kinetics; D008567:Membranes, Artificial; D008954:Models, Biological; D010713:Phosphatidylcholines
D007473:Ion Channels; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D000666:Amphotericin B; D002784:Cholesterol
Izmenenie bol't-ampernoĭ kharakteristiki ionnykh kanalov amfoteritsina B pri ego vstraivanii v membranu.