[Capillary embolization. Part II. Occlusion of the entire arterial system of experimentally induced renal tumors ].
221 renal rat tumors (induced by Dimethylnitrosamine) are embolized by gelfoam powder, IBC/Lipiodol and Ethibloc/Glucose. The effect of those embolization media is compared to ligation and glucose perfusion. Recurrencies and rate of surviving tumor tissue are dependent on the stage of the neoplasm, sufficient capillary propagation of the medium, and exact volume-dependent embolization. It could be proven that large areas of renal rat tumors are equally supplied by the main artery and parasitary collaterals. Only homogeneous distribution and complete downstream propagation of the embolization medium from the main artery to the capillaries will achieve breakdown of this parasitary supply. Glucose governed Ethibloc embolization achieves in 80% of tumors with a 6 fold renal volume and in 50% of larger tumors complete necrosis. It has the lowest complication rate of all tested materials.
D000818:Animals; D001027:Aortography; D002015:Bucrylate / Q000008:administration & dosage; D003973:Diatrizoate; D004128:Dimethylnitrosamine; D004338:Drug Combinations; D004621:Embolization, Therapeutic / Q000379:methods; D005227:Fatty Acids; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000008:administration & dosage; D007459:Iodized Oil / Q000008:administration & dosage; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000473:pathology / Q000628:therapy*; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology / Q000628:therapy; D011409:Propylene Glycols; D011506:Proteins / Q000008:administration & dosage; D051381:Rats; D011919:Rats, Inbred Strains; D015028:Zein
D004338:Drug Combinations; D005227:Fatty Acids; D011409:Propylene Glycols; D011506:Proteins; D003973:Diatrizoate; D002015:Bucrylate; D007459:Iodized Oil; D015028:Zein; C020481:alcoholic prolamine solution; D004128:Dimethylnitrosamine
Kapilläre Embolisation. Teil 2: Verschluss des gesamten arteriellen Gefässsystems experimentell erzeugter Nierentumoren.