[Changes in the cAMP level in macrophages in Salmonella typhimurium phagocytosis].
The effect of a virulent S. typhimurium strain and its cAMP-deficients mutant on the level of cAMP in macrophages in the process of phagocytosis has been studied. The virulent strain has been shown to induce the 3-fold increase of the level of cAMP in macrophages, while the mutant renders no such effect.
D000818:Animals; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000378:metabolism*; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000382:microbiology; D008264:Macrophages / Q000378:metabolism*; D051379:Mice; D009154:Mutation; D010587:Phagocytosis; D011817:Rabbits; D012486:Salmonella typhimurium / Q000378:metabolism / Q000472:pathogenicity*; D013997:Time Factors; D014774:Virulence
D000242:Cyclic AMP
Izmenenie urovnia ts-AMF v makrofagakh pri fagotsitoze Salmonella typhimurium.