Role of the sfiA-dependent cell division regulation system in Escherichia coli.
Several authors have suggested that the SOS-associated (sfiA-dependent) system of division inhibition, normally induced by perturbations of DNA replication, also regulates steady-state (unperturbed) cell division. The present work shows that mean cell mass is identical in sfiA+ and sfiA mutant cultures during steady-state growth, that mass adjustment is identical after shift up, that sfiA expression is not induced by shift up, and that a sfiA mutation does not cause aberrant chromosome segregation.
D001426:Bacterial Proteins / Q000502:physiology*; D002455:Cell Division; D002876:Chromosomes, Bacterial / Q000378:metabolism; D004261:DNA Replication; D004269:DNA, Bacterial / Q000378:metabolism; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics / Q000502:physiology; D005798:Genes, Bacterial; D009154:Mutation
D001426:Bacterial Proteins; D004269:DNA, Bacterial