title: [Fundamental and clinical studies on cefotaxime in the field of obstetrics and gynecology (author's transl)].
abstract: Fundamental and clinical studies were made on cefotaxime (HR-756, CTX), a new cephalosporin antibiotic, with the following results. 1. Cefotaxime was given to 22 patients. Efficacy was excellent in 3 cases, good in 17 cases and poor in 2 cases. No side effects were observed in any cases. 2. Following a single intravenous injection of 1.0 or 2.0 g, the transfer of CTX to the internal genital organs was found to be good. The transfer of CTX to exudate of the dead space of pelvis was also good. 3. The above data demonstrated that CTX is a safe and effective drug.
mesh_terms: D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy; D010388:Pelvis; D010538:Peritonitis / Q000188:drug therapy*
chemical_list: D002439:Cefotaxime