[The pathogenetic importance of peanut lectin binding sites in infectious, toxic and neoplastic processes].
Labelled lectins are generally used for identification of mono-, oligo- and polysaccharides in histochemistry. The aim of this work is to demonstrate in addition the importance of the labelled (FITC and peroxidase) lectin from peanut (peanut agglutinin = PNA) with regard to the pathogenesis of some infectious and neoplastic diseases. Thereby, PNA-binding sites have been shown as differentiation marker in embryonic kidneys and in dysontogenetic.
D010367:Arachis; D001665:Binding Sites; D001943:Breast Neoplasms / Q000378:metabolism; D002831:Choroid Plexus / Q000473:pathology; D003110:Colonic Neoplasms / Q000378:metabolism; D006023:Glycoproteins / Q000096:biosynthesis; D006651:Histocytochemistry; D006801:Humans; D007678:Kidney Glomerulus / Q000032:analysis / Q000473:pathology; D037102:Lectins; D009363:Neoplasm Proteins / Q000096:biosynthesis; D009369:Neoplasms / Q000378:metabolism*; D009439:Neuraminidase / Q000378:metabolism; D019887:Peanut Agglutinin; D037121:Plant Lectins; D011008:Pneumococcal Infections / Q000378:metabolism*; D011975:Receptors, Mitogen / Q000032:analysis*; D009396:Wilms Tumor / Q000378:metabolism
D006023:Glycoproteins; D037102:Lectins; D009363:Neoplasm Proteins; D019887:Peanut Agglutinin; D037121:Plant Lectins; D011975:Receptors, Mitogen; D009439:Neuraminidase
Allgemeine pathogenetische Bedeutung der Bindungsstellen für das Lektin der Erdnuss bei infektiös-toxischen und neoplastischen Prozessen.