title: Do sulphonamide-trimethoprim combinations select less resistance to trimethoprim than the use of trimethoprim alone?
mesh_terms: D004251:DNA Transposable Elements; D004338:Drug Combinations; D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D004926:Escherichia coli / Q000187:drug effects; D005493:Folic Acid Antagonists; D006801:Humans; D009154:Mutation; D010957:Plasmids; D013449:Sulfonamides / Q000494:pharmacology* / Q000627:therapeutic use; D013936:Thymidine / Q000378:metabolism; D013941:Thymine / Q000378:metabolism; D014295:Trimethoprim / Q000494:pharmacology* / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D004251:DNA Transposable Elements; D004338:Drug Combinations; D005493:Folic Acid Antagonists; D013449:Sulfonamides; D014295:Trimethoprim; D013941:Thymine; D013936:Thymidine