Childhood acromegaly successfully treated with interstitial irradiation using yttrium-90.
A child with a growth hormone producing tumour presented at the age of 4 1/2 years. The onset of the disease was at 18 months of age. Treatment was given with three doses of interstitial irradiation using yttrium-90 implants. There were no local complications from the procedures. Now, 11 years after diagnosis, she is asymptomatic, of normal appearance, and her height and the size of the pituitary fossa are normal. Growth hormone levels are almost normal, thyroid function is intact, and she is maintained on prednisone and sex hormones.
D000239:Adenoma, Acidophil / Q000097:blood / Q000532:radiotherapy*; D000293:Adolescent; D001827:Body Height; D005260:Female; D006801:Humans; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000097:blood / Q000532:radiotherapy*; D011388:Prolactin / Q000097:blood; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
D015021:Yttrium Radioisotopes; D011388:Prolactin