Upper motor neurone modulation of the structure of the terminal cisternae in rat skeletal muscle fibres.
There are fewer indentations on the flat surfaces of terminal cisternae in soleus (slow-twitch) than in extensor digitorum longus (EDL, fast-twitch) muscle fibres of rats. Following mid-thoracic spinal cord transection, there is an increase in the number of indentations in soleus fibres but no change in EDL fibres. The increase in the numbers of indentations after spinal cord transections is correlated with changes in the contractile and charge movement properties of the soleus fibres so that they resemble normal EDL fibres. The indentations appear to have an important role in excitation-contraction coupling.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005614:Freeze Fracturing; D008297:Male; D008564:Membrane Potentials; D009046:Motor Neurons / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D051381:Rats; D011919:Rats, Inbred Strains; D012519:Sarcoplasmic Reticulum / Q000648:ultrastructure*; D013116:Spinal Cord / Q000502:physiology; D009435:Synaptic Transmission
D002118:Calcium