title: [Restriction endonuclease study of interstrain differences in the DNA of herpes simplex virus type 1].
abstract: Electrophoregrams of the products of cleavage of DNA of 4 HSV-1 strains by restrictases Xbal, Hind III, and Sau 18/4 were compared. The sets of fragments obtained by the effect of Xbal restrictase on DNA of all 4 strains were found to be identical. At the same time, analysis of the products of DNA hydrolysis by Hind III and Sau 18/4 revealed significant interstrain differences.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004262:DNA Restriction Enzymes / Q000494:pharmacology*; D004279:DNA, Viral / Q000032:analysis* / Q000145:classification / Q000302:isolation & purification; D004587:Electrophoresis, Agar Gel; D008970:Molecular Weight; D018139:Simplexvirus / Q000032:analysis*; D014776:Virus Cultivation
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes
vernacular_title: Issledovanie mezhshtammovykh razlichiĭ DNK virusa prostogo gerpesa tipa 1 s pomoshch'iu restriktsionnykh éndonukleaz.