[Comparative study of light and electron microscopic aspects of myocardial lesions induced in the rat by oils with several amounts of gamma-linolenic acid (author's transl)].
Four different oils : onager oil, mixture of onager oil (20 p. cent) and middle class triglyceride, sunflower oil and soybean oil were given to the rat during three different periods of time : 1) during 3 months after weaning ; 2) during 6 months after weaning ; 3) from the 9th to 15th months. Three types of myocardial lesions were found : interstitial inflammatory reaction, foci of cellular necrosis and fibrosis. The semi-quantitative study of these lesions did not find important differences from one oil to the other, as well as with the controls. However, subgroups onager are among the least altered, particularly as far as necrotic lesions are concerned. Morphometry of mitochondria, despite evident alterations under electron microscope, gave similar results in every groups.
D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology*; D006321:Heart / Q000254:growth & development*; D006368:Helianthus; D008042:Linolenic Acids / Q000008:administration & dosage*; D008854:Microscopy, Electron; D009205:Myocarditis / Q000473:pathology; D009206:Myocardium / Q000648:ultrastructure; D009336:Necrosis; D009821:Oils / Q000008:administration & dosage*; D051381:Rats; D011919:Rats, Inbred Strains; D013025:Glycine max; D017965:gamma-Linolenic Acid
D008042:Linolenic Acids; D009821:Oils; D017965:gamma-Linolenic Acid
Etude comparative au microscope optique et électronique des lésions myocardiques induites chez le rat après administration d'huiles a différentes teneurs en acide gamma-linolénique.