title: A steroid derivative, R 5135, antagonizes the GABA/benzodiazepine receptor interaction.
mesh_terms: D000731:Androstanes; D000818:Animals; D001378:Azasteroids / Q000494:pharmacology*; D002712:Chlorides / Q000494:pharmacology; D003975:Diazepam / Q000378:metabolism; D005998:Glycine / Q000378:metabolism; D008297:Male; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects* / Q000378:metabolism; D011955:Receptors, Drug / Q000187:drug effects* / Q000378:metabolism; D011963:Receptors, GABA-A; D013260:Steroids, Heterocyclic / Q000494:pharmacology*; D013331:Strychnine / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism / Q000494:pharmacology
chemical_list: D000731:Androstanes; D001378:Azasteroids; D002712:Chlorides; D011956:Receptors, Cell Surface; D011955:Receptors, Drug; D011963:Receptors, GABA-A; D013260:Steroids, Heterocyclic; D005680:gamma-Aminobutyric Acid; D013331:Strychnine; D003975:Diazepam; C032061:RU 5135; D005998:Glycine