CEA-like material in cytosols from human breast carcinomas. Correlation with biochemical and pathologic parameters.
CEA-like material was found in 51 of 62 primary human breast carcinomas and in only 2 of 12 fibroadenomas. Levels of carcinoma CEA-like material correlated weakly with cytoplasmic estradiol receptor levels, total cytosol estrogens, and cytosol progesterone. Levels of CEA-like material showed no significant correlation with carcinoma stage, grade, cellularity, size or histologic type. Levels, however, correlated inversely with lymphocyte infiltration.
D000232:Adenofibroma / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D001943:Breast Neoplasms / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D002467:Cell Nucleus / Q000032:analysis; D003593:Cytoplasm / Q000032:analysis; D003600:Cytosol / Q000032:analysis / Q000276:immunology; D004967:Estrogens / Q000032:analysis; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D011374:Progesterone / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis
D002272:Carcinoembryonic Antigen; D004967:Estrogens; D011960:Receptors, Estrogen; D011374:Progesterone