title: [Mechanism of action of non-steroidal antirheumatic agents].
abstract: Non-steroidal antirheumatic drugs permit a nonspecific, symptomatic therapy of inflammatory rheumatic processes and may also be given for a limited period of time in patients with so-called activated osteoarthrosis. Their mode of action is a complex one. More recent knowledge on mediators in inflammation such as prostaglandins, leukotriens and oxygen radicals have brought new insights on the mode of action of non-steroidal antirheumatic drugs.
mesh_terms: D000698:Analgesia; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D004791:Enzyme Inhibitors; D005334:Fever / Q000188:drug therapy; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D007165:Immunosuppression Therapy; D007975:Leukotriene B4 / Q000096:biosynthesis; D010003:Osteoarthritis / Q000188:drug therapy*; D010100:Oxygen / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000096:biosynthesis; D012216:Rheumatic Diseases / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D004791:Enzyme Inhibitors; D005609:Free Radicals; D011453:Prostaglandins; D007975:Leukotriene B4; D010100:Oxygen
vernacular_title: Wirkungsweise nichtsteroidaler Antirheumatika.