[Management of acute lymphoblastic leukemia in adults. Retrospective review of fifty case-reports (author's transl)].
In adults, acute lymphoblastic leukemia (ALL) is less frequent and less clearly defined than in children. A retrospective study of fifty adult patients with ALL was carried out. Findings were similar to those reported in previous studies. Complete remission was achieved in 86% of patients. This rate is similar to that recorded in children with ALL. Median survival (twenty months) was shorter than in childhood because of frequent relapses. Various factors of prognostic value are discussed. Problems encountered in attempting immunological classification are studied. Prognosis seems to be related to the intensiveness of induction therapy and the choice of maintenance therapy regimen.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy*; D008875:Middle Aged; D011379:Prognosis
D000970:Antineoplastic Agents
Traitement des leucémies aiguës lymphoblastiques de l'adulte. Etude d'une série de cinquante cas.