Cyclic nucleotides in anatomical subdivisions of the bovine lens.
Adenosine 3', 5'-cyclic monophosphate (cAMP) and guanosine 3', 5'-cyclic monophosphate (cGMP) have been measured in whole and anatomically subdivided areas of bovine lenses. The highest values of cAMP and cGMP (2.843 pmoles/mg protein and 0.0139 pmoles/mg protein respectively) were found in the epithelium. In contrast, the lowest values of cAMP and cGMP (.007 pmoles/mg protein and .001 pmoles/mg protein respectively) were detected in the central nucleus. Values for the cyclic nucleotides in the whole tissue more closely resembled those of the whole nucleus.
D000818:Animals; D002417:Cattle; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D004848:Epithelium / Q000032:analysis; D007908:Lens, Crystalline / Q000032:analysis*
D000242:Cyclic AMP; D006152:Cyclic GMP