Growth and persistence of polyoma early region deletion mutants in mice.
Replication of early region deletion mutations in polyoma in the kidneys of mice was in most cases reduced by 10- to 10,000-fold, as compared with wild-type polyoma, and the mutants failed to produce the persistent infection observed with wild-type polyoma.
D000818:Animals; D000951:Antigens, Neoplasm / Q000235:genetics; D000956:Antigens, Viral / Q000235:genetics; D000957:Antigens, Viral, Tumor; D005814:Genes, Viral; D007668:Kidney / Q000382:microbiology*; D051379:Mice; D009154:Mutation; D011120:Polyomavirus / Q000235:genetics* / Q000254:growth & development; D014412:Tumor Virus Infections / Q000382:microbiology*; D014779:Virus Replication
D000951:Antigens, Neoplasm; D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor