Rabbit atrial histamine receptors and cyclic AMP.
The present study confirms the presence of H2 receptors in rabbit right and left atrium by measuring changes in cyclic AMP. Histamine produced significant increases in cyclic AMP in both atria although the increases were less in left atria. Since H2 receptors are always associated with the adenylate cyclase--cyclic AMP system, the data provide further support for the suggestion that H2 receptors exit in rabbit right and left atria.
D000818:Animals; D000242:Cyclic AMP / Q000032:analysis*; D006339:Heart Rate; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D009200:Myocardial Contraction; D009206:Myocardium / Q000032:analysis*; D011817:Rabbits; D011968:Receptors, Histamine / Q000032:analysis*
D011968:Receptors, Histamine; D006632:Histamine; D000242:Cyclic AMP