Genetic variation in testicular LH receptors in the mouse.
The concentration of testicular hCG (LH) binding sites was measured in five mutants with defective endocrine and/or reproductive functions, in a hypoandrogenic inbred strain and in six normal strains. A decrease in hCG binding was found in dw/dw mice, and an increase in Tfm/y and C57Bl10/J mice. Analysis of the results indicates the existence of a genetic factor(s) involved in the regulation of hCG (LH) binding.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000378:metabolism; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics; D011956:Receptors, Cell Surface / Q000032:analysis / Q000235:genetics*; D011974:Receptors, LH; D013045:Species Specificity; D013737:Testis / Q000032:analysis* / Q000033:anatomy & histology
D006063:Chorionic Gonadotropin; D011956:Receptors, Cell Surface; D011974:Receptors, LH