Inhibition of ovulation and LH secretion in the gilt after treatment with ACTH or hydrocortisone.
Treatment with ACTH (100 i.u.) or hydrocortisone acetate (250 mg) twice daily for 12 days to increase cortisol concentrations blocked ovulation in all gilts. The preovulatory surge of LH was also blocked in the treated gilts. Oestrous cycle length and number of days in oestrus were similar for all treatments except that in one of the 2 experiments ACTH suppressed oestrus in 4 of the 5 gilts treated.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D003864:Depression, Chemical; D004971:Estrus / Q000187:drug effects; D005260:Female; D006854:Hydrocortisone / Q000097:blood / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D006080:Ovarian Follicle / Q000187:drug effects; D010060:Ovulation / Q000187:drug effects*; D011247:Pregnancy; D012636:Secretory Rate / Q000187:drug effects; D013552:Swine / Q000502:physiology*
D000324:Adrenocorticotropic Hormone; D007986:Luteinizing Hormone; D006854:Hydrocortisone