The influence of Na+ on the alpha 2-adrenergic receptor system of human platelets. A method for removal of extraplatelet Na+. Effect of Na+ removal on aggregation, secretion, and cAMP accumulation.
D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D000242:Cyclic AMP / Q000097:blood*; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D008854:Microscopy, Electron; D010974:Platelet Aggregation / Q000187:drug effects*; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000378:metabolism*; D012701:Serotonin / Q000097:blood; D012964:Sodium / Q000494:pharmacology*; D013917:Thrombin / Q000502:physiology
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D012701:Serotonin; D012964:Sodium; D000242:Cyclic AMP; D013917:Thrombin; D004837:Epinephrine