Pancreatic isleitis with coxsackie virus B5 infection.
Coxsackie group B virus infection may be responsible for some cases of insulin-dependent diabetes mellitus. However, Coxsackie B5 virus is rarely implicated in this respect. The authors observed striking pancreatic islet cell damage in an infant who died of a Coxsackie B5 virus infection. The inflammatory response consisted of mononuclear cells, and the acinar tissue was completely uninvolved.
D003384:Coxsackievirus Infections / Q000150:complications*; D003920:Diabetes Mellitus / Q000209:etiology* / Q000382:microbiology; D029822:Enterovirus B, Human / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007515:Islets of Langerhans / Q000473:pathology; D010179:Pancreas / Q000382:microbiology