Fibrous histiocytoma of the corneosclera.
A 65-year-old woman had a slowly progressive sclerocorneal lesion that, after three years of unsuccessful medical treatment, involved almost the whole cornea and the surrounding sclera in the temporal lower quadrant. The tumor had a nodular surface. During the next two years, the tumor was operated on four times (twice by keratectomy and twice by lamellar sclerokeratoplasty). Microscopic examination revealed a fibrous histiocytoma. The resection was histologically incomplete on all occasions. Five years after the onset of the disease, the eye was enucleated. A spontaneous invasion of the iris could not be diagnosed with certainty, because there was a perforation at the limbus during a preceding operation.
D000368:Aged; D003316:Corneal Diseases / Q000473:pathology* / Q000601:surgery; D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D012590:Sclera / Q000473:pathology*