title: Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction.
mesh_terms: D003166:Complement Activating Enzymes / Q000378:metabolism*; D015923:Complement C1r; D004789:Enzyme Activation; D005456:Fluorescent Dyes; D006801:Humans; D010069:Oxadiazoles; D011487:Protein Conformation; D013050:Spectrometry, Fluorescence; D013696:Temperature
chemical_list: D005456:Fluorescent Dyes; D010069:Oxadiazoles; C001727:7-(4-methoxybenzylamino)-4-nitrobenzoxadiazole; D003166:Complement Activating Enzymes; D015923:Complement C1r