title: Tandem repeat of the genes for protein S, a development-specific protein of Myxococcus xanthus.
abstract: Protein S, a development-specific protein of Myxococcus xanthus is produced only during fruiting body formation. More than 15% of total protein synthesis during this period is accounted for by the production of protein S. The genes for protein S were identified and cloned with the use of mixed probes consisting of eight synthetic oligodeoxyribonucleotides (tetradecamers) which correspond to a carboxyl-terminal portion of protein S. The two genes are oriented in the same direction and are separated approximately 1.2 kilobases. The DNA sequences of the carboxyl-terminal portions of the two genes reveal that both can code for the identical eleven amino acid sequence which corresponds to the carboxyl-terminal end of protein S. However, there are a few base substitutions upstream of these regions. This duplication of genes in M. xanthus may facilitate the extremely rapid synthesis of protein S during fruiting body formation.
mesh_terms: D001419:Bacteria / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D004262:DNA Restriction Enzymes; D004269:DNA, Bacterial / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; C024278:protein S, Myxococcus xanthus; D004262:DNA Restriction Enzymes