title: Neuronal and glial cells in the superficial layers of early postnatal mouse neocortex: immunofluorescence observations.
abstract: Sections of immature (postnatal day 5) mouse cerebral cortex was examined for several cell-type specific immunological markers. Glial fibrillary acidic (GFA) protein or vimentin were detected in astrocytic cell processes and--more rarely--cell bodies located in the superficial layers, but not within putative Cajal-Retzius cells (CRs). These cells did, however, react with cholera toxin, tetanus toxin and NS-4 antibodies. In agreement with previous ultrastructural observations, we conclude that CRs are neurons, or at least cells which display the basic characteristics of neurons.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D000906:Antibodies / Q000032:analysis; D002540:Cerebral Cortex / Q000166:cytology*; D005455:Fluorescent Antibody Technique; D005904:Glial Fibrillary Acidic Protein; D051379:Mice; D009124:Muscle Proteins / Q000276:immunology; D009419:Nerve Tissue Proteins / Q000276:immunology; D009457:Neuroglia / Q000145:classification* / Q000276:immunology; D009474:Neurons / Q000145:classification* / Q000276:immunology; D014746:Vimentin
chemical_list: D000906:Antibodies; D005904:Glial Fibrillary Acidic Protein; D009124:Muscle Proteins; D009419:Nerve Tissue Proteins; D014746:Vimentin