Extraneural metastasis of cerebellar glioblastoma multiforme.
The case of a 7-year-old girl with a cerebellar glioblastoma and extraneural metastases has been presented. The dura mater was left open at the time of tumor resection. Postoperative hydrocephalus caused prolonged bulging of the incision. We believe that an open dura mater facilitates continuous exposure of extrameningeal tissue to glioma cells that are capable of invading local lymphatics and extracerebral veins, enhancing the probability of widespread dissemination. We suggest that every effort should be made to close the posterior fossa dura mater after resection of a malignant tumor.
D001859:Bone Neoplasms / Q000556:secondary*; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000601:surgery; D002648:Child; D003388:Cranial Fossa, Posterior; D005260:Female; D005909:Glioblastoma / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D009366:Neoplasm Seeding