Mapping the substrate binding site of human C1r and C1s with peptide thioesters. Development of new sensitive substrates.
D001665:Binding Sites; D003166:Complement Activating Enzymes / Q000378:metabolism*; D015923:Complement C1r; D003173:Complement C1s; D004792:Enzyme Precursors / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D010455:Peptides / Q000138:chemical synthesis*; D011485:Protein Binding; D013379:Substrate Specificity; D013438:Sulfhydryl Compounds / Q000494:pharmacology
D004792:Enzyme Precursors; D010455:Peptides; D013438:Sulfhydryl Compounds; D003166:Complement Activating Enzymes; D015923:Complement C1r; D003173:Complement C1s