[Hairy cell leukemia. II.--Critical review of literature. Part. 1:diagnosis and evolution (author's transl)].
Hairy cell leukemia (in french: leucémie à tricholeucocytes) is a distinctive form of chronic leukemia with splenomegaly, pancytopenia, presence of a particular circulating mononuclear cell, myelofibrosis and leukemia infiltration of the bone marrow. Generally, a tartrate resistant acid phosphatase activity is found in the leukemic cells. Hairy cell leukemia is the main leukemia in which the treatment is first surgical. Splenectomy has a good result for survival median and infectious risk. The disease is still mysterious for the origin of the leukemic cell; monocyte, B lymphocyte or in few cases T lymphocyte, even though a spectrum of immunological patterns pleads for the B lymphocyte origin of the leukemic cell.
D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D007962:Leukocytes / Q000473:pathology; D011379:Prognosis; D013156:Splenectomy; D013163:Splenomegaly / Q000209:etiology
La leucémie à tricholeucocytes (hairy cell leukemia) II.--Revue critique de la littérature. 1re partie: diagnostic et évolution.