[Surface morphology of normal and virus-transformed cells in suspended state and their concanavalin A agglutinability].
Suspended cells are heterogeneous in respect to their surface microrelief. The distribution of different microrelieves varies in different cultures. It depends on the mode of cell detachment from the substrate - by EDTA or trypsin. Oncogenic transformation is accompanied by both the increase and decrease of microvillous microrelief. There is no correlation between the surface morphology of transformed cells and their agglutinability by concanavalin A. The treatment with trypsin results in the increase of both agglutinability by concanavalin A and microvillious microrelief.
D000371:Agglutination; D000818:Animals; D002472:Cell Transformation, Viral / Q000187:drug effects*; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology*; D006224:Cricetinae; D007708:Kirsten murine sarcoma virus / Q000472:pathogenicity; D051379:Mice; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000187:drug effects / Q000648:ultrastructure; D008907:Mink; D012513:Sarcoma, Experimental / Q000648:ultrastructure; D013539:Simian virus 40 / Q000472:pathogenicity; D013499:Surface Properties; D014412:Tumor Virus Infections / Q000473:pathology
D003208:Concanavalin A
Morfologiia poverkhnosti normal'nykh i transformirovannykh virusami kletok v suspendirovannom sostoianii i ikh aggliutinabel'nost' konkanavalinom A.