title: MAXAMIZE. A DNA sequencing strategy advisor.
abstract: The MAXAMIZE advisory system determines from user-provided restriction maps an optimal strategy to do nucleotide sequencing by methods involving end-labeled fragments. The maps may be either simple linear restriction maps of fragments or complex circular maps including restriction sites of a vector. The whole system is interactive and is written in the Genetic English language provided by the GENESIS System, a molecular genetics knowledge representation and manipulation package. In addition, MAXAMIZE provides bookkeeping facilities for sequencing and offers advise on how to verify the newly obtained sequence data.
mesh_terms: D001483:Base Sequence; D003201:Computers; D004247:DNA; D004262:DNA Restriction Enzymes / Q000378:metabolism; D004270:DNA, Circular; D008722:Methods
chemical_list: D004270:DNA, Circular; D004247:DNA; D004262:DNA Restriction Enzymes