A family affected with intestinal polyposis and gliomas.
The third affected family with Turcot syndrome is presented and the problems associated with the occurrence of familial aggregates of cancer are discussed. Turcot syndrome represents the unique and discrete occurrence of polyposis coli with glioblastoma multiforme, medulloblastoma, or both.
D000293:Adolescent; D001932:Brain Neoplasms / Q000235:genetics*; D002648:Child; D003110:Colonic Neoplasms / Q000235:genetics; D005260:Female; D005625:Frontal Lobe; D005909:Glioblastoma / Q000235:genetics*; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics*; D008297:Male; D008527:Medulloblastoma / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D009778:Occipital Lobe; D013577:Syndrome; D013702:Temporal Lobe