A new Epstein-Barr virus negative Burkitt's lymphoma derived cell-line. I. Analysis of cell surface markers and abnormal expression of HLA antigens.
CHEV, a new Epstein-Barr virus negative Burkitt's lymphoma derived cell line has been studied. Karyotype analyses demonstrated the t (8; 14) characteristic translocation. Cell surface characterisation of this line showed the presence of mu and chi immunoglobulin chains and beta 2-microglobulin and the absence of the complement receptor. We are unable to detect HLA--A, B alloantigens on the cell surface which was in contrast with an apparently normal expression of these antigens in the cytoplasm.
D000951:Antigens, Neoplasm / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D002051:Burkitt Lymphoma / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D002455:Cell Division; D002460:Cell Line; D006680:HLA Antigens / Q000032:analysis; D004854:Herpesvirus 4, Human; D006801:Humans; D007621:Karyotyping; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D001613:beta 2-Microglobulin / Q000032:analysis
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D006680:HLA Antigens; D011947:Receptors, Antigen, B-Cell; D001613:beta 2-Microglobulin