Breast carcinoma in a 46, XX true hermaphrodite.
Muscinous breast carcinoma occurred in a 67-year-old true hermaphrodite who had been reared as a male. The peripheral blood karyotype was 46, XX. A left ovary and right ovotestis were intra-abdominal. Other tumors included an ovarian thecoma and an intestinal leiomyoma. Two previously reported cases of breast cancer in true hermaphrodites are cited.
D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D012734:Disorders of Sex Development / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010053:Ovary / Q000002:abnormalities; D012729:Sex Chromosome Aberrations / Q000235:genetics; D013737:Testis / Q000002:abnormalities; D014998:Y Chromosome