title: [Cultivation of Bordetella pertussis in liquid semisynthetic nutrient media with ion-exchange resins].
abstract: The possibility of optimizing the processes of B. pertussis cultivation carried out in liquid semisynthetic culture media with strong-base anion-exchange resins is shown. The use of strong-base ionites enhances the reproducibility of cultivation processes, increases the activity of microbial populations and the concentration of microorganisms. B. pertussis cultures grown in the media with anion-exchange resins are characterized by pronounced biological activity.
mesh_terms: D000818:Animals; D000837:Anion Exchange Resins / Q000494:pharmacology; D001427:Bacterial Toxins / Q000096:biosynthesis; D001886:Bordetella pertussis / Q000254:growth & development* / Q000276:immunology / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D003470:Culture Media; D007475:Ion Exchange Resins / Q000494:pharmacology*; D051379:Mice; D014611:Vaccination; D014917:Whooping Cough / Q000517:prevention & control
chemical_list: D000837:Anion Exchange Resins; D001427:Bacterial Toxins; D003470:Culture Media; D007475:Ion Exchange Resins
vernacular_title: Kul'tivirovanie kokliushnykh bakteriĭ v zhidkikh polusinteticheskikh pitatel'nykh sredakh s ionoobmennymi smolami.