Differential pulse polarography of the catalytic waves in serum from patients with urological cancers.
Catalytic waves obtained from the perchloric acid-soluble fraction of serum in the presence of hexaminecobalt trichloride appear to conform to a Langmuir adsorption isotherm. Wave heights for sera from patients with untreated urological cancers significantly exceed those from normal subjects. In general, treatment with diethylstilbestrol decreased the wave height. Effects of some other chemotherapeutic agents on wave heights are also noted.
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001798:Blood Proteins / Q000032:analysis*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004054:Diethylstilbestrol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010472:Perchlorates; D011048:Polarography / Q000379:methods; D014571:Urologic Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000601:surgery
D000970:Antineoplastic Agents; D001798:Blood Proteins; D010472:Perchlorates; D004054:Diethylstilbestrol; D003520:Cyclophosphamide