[Anatamo-pathologic aspects of gold-salt induced cholestasis. Report of two cases with ultrastructural study (author's transl)].
The authors report two cases of gold-salt-induced cholestasis. They make a review of the thirteen cases previously related in the literature ; the cholestasis was constant, the hepatocytic necrosis was unusual and the gold-salts were difficult to visualize in the liver biopsy and more especially at the ultrastructural level. The immunological mechanism of hypersensibility is well established ; the possibility of an associated hepatotoxicity is debated.
D000368:Aged; D002779:Cholestasis / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006046:Gold / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000473:pathology / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged
D006046:Gold
Aspects anatomo-patholgiques de l'hépatite cholestatique aux sels d'or. A propos de deux observations avec étude ultrastructurale.