title: Separate populations of cholecystokinin and 5-hydroxytryptamine-containing neuronal cells in the rat dorsal raphe, and their contribution to the ascending raphe projections.
abstract: Successive immunohistofluorescent staining for cholecystokinin and 5-hydroxytryptamine (5-HT) was combined with fluorescent retrograde axonal tracing to analyze ascending projections from the rat dorsal raphe nucleus. Cholecystokinin-like immunoreactive cell bodies were situated both rostral and caudal to the 5-HT-immunoreactive perikarya in the dorsal raphe. Only the 5-HT immunoreactive neurones could be retrogradely labelled after injections of fluorescent axonal tracers into various forebrain areas.
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001921:Brain / Q000502:physiology; D001933:Brain Stem / Q000166:cytology*; D002766:Cholecystokinin / Q000502:physiology*; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D008297:Male; D009474:Neurons / Q000502:physiology*; D011903:Raphe Nuclei / Q000166:cytology* / Q000502:physiology; D051381:Rats; D012701:Serotonin / Q000502:physiology*; D009435:Synaptic Transmission
chemical_list: D012701:Serotonin; D002766:Cholecystokinin