Immunogenicity of a subviral herpes simplex type 1 preparation: reduction of recurrent disease in mice.
Immunization of mice with a relatively small dose of subviral herpes simplex type 1 vaccine used prior to homotypic virus infection reduced the frequency of recurrent disease. However, the same vaccine dose administered after virus infection did not result in significant reduction of recurrences.
D000818:Animals; D006561:Herpes Simplex / Q000517:prevention & control*; D051379:Mice; D012008:Recurrence; D018139:Simplexvirus / Q000276:immunology*; D014611:Vaccination; D014765:Viral Vaccines / Q000008:administration & dosage
D014765:Viral Vaccines