Use of the muscle relaxant atracurium in anephric patients: preliminary communication.
Atracurium is a new, non-depolarizing muscle relaxant which rapidly breaks down in vivo and appears to require neither renal nor hepatic function for its elimination. As the commonly used non-depolarizing muscle relaxants carry the risk of prolonged effect when used in anephric patients, atracurium appears to have special promise in this situation. A preliminary account of the successful use of the relaxant in 20 anephric patients is recorded and evidence presented that atracurium is, indeed, a suitable agent for use in patients with renal failure.
D000759:Adjuvants, Anesthesia; D000328:Adult; D001279:Atracurium; D006801:Humans; D007546:Isoquinolines; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents; D009469:Neuromuscular Junction / Q000503:physiopathology; D009435:Synaptic Transmission
D000759:Adjuvants, Anesthesia; D007546:Isoquinolines; D009466:Neuromuscular Blocking Agents; D001279:Atracurium