title: The genome of Plasmodium falciparum. I: DNA base composition.
abstract: Some structural properties of the DNA of Plasmodium falciparum were studied thoroughly using several techniques. Its G+C content was found to be extremely low (17-19%), the lowest reported for a living organism. The DNA seems to be composed only of the four major bases as no methylated bases were detected. This DNA had a Tm value of 62.5 degrees C and its denaturation profile showed no marked intramolecular heterogeneity.
mesh_terms: D000818:Animals; D001482:Base Composition; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000235:genetics*; D004262:DNA Restriction Enzymes; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D010963:Plasmodium falciparum / Q000235:genetics*
chemical_list: D004247:DNA; D004262:DNA Restriction Enzymes