[Solubilization of myxovirus surface glycoproteins by using a nonionic detergent octylglucoside].
Using alpha- and beta-forms of the non-ionic detergent octyl glucoside the conditions have been developed for treatment of influenza virus and Sendai virus suspensions with the purpose of solubilization from virions of exclusively surface glycoproteins. Both alpha- and beta-forms of the detergent have been shown to have similar effectiveness for the recovery of chromatographically pure preparations of surface glycoproteins.
D003902:Detergents / Q000494:pharmacology*; D005960:Glucosides / Q000494:pharmacology*; D006023:Glycoproteins / Q000302:isolation & purification*; D006027:Glycosides / Q000494:pharmacology*; D009980:Influenza A virus / Q000187:drug effects; D008854:Microscopy, Electron; D009975:Orthomyxoviridae / Q000187:drug effects*; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects; D012995:Solubility; D013499:Surface Properties; D013501:Surface-Active Agents / Q000494:pharmacology*
D003902:Detergents; D005960:Glucosides; D006023:Glycoproteins; D006027:Glycosides; D013501:Surface-Active Agents; C018619:octyl-beta-D-glucoside
Soliubilizatsiia poverkhnostnykh glikoproteidov miksovirusov s pomoshch'iu neionnogo detergenta oktilgliukozida.