title: Metabolic and endocrine changes in spinal cord injury: III. Less quanta of sensory input plus bedrest and illness.
abstract: This is the fourth article (Part III) of a 4-part series which provides a comprehensive review and analysis of the pertinent literature published over the last 25 years on the metabolic and endocrine consequences of spinal cord injury (SCI). The studies on SCI patients reviewed in this article include reports and investigations concerning plasma ACTH, plasma and urine corticosteroids and their diurnal variations at rest and during stress, of fasting values of TSH and growth hormone, thyroxine, testosterone, and of urinary skin collagen metabolites and urinary tryptamine. Information from articles reviewed here is organized under the following headings: Problems studied, Methods of investigation and results, Conclusions, Summary of results, Discrepancies, Areas of research needed, and Practical clinical implications. Highlights of pertinent data contained in the original articles are organized in tables to facilitate direct comparisons between similar studies and between data on healthy and subjects with spinal cord injuries.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000097:blood; D001510:Bed Rest; D001921:Brain / Q000378:metabolism; D002940:Circadian Rhythm; D003094:Collagen / Q000652:urine; D006801:Humans; D012867:Skin / Q000378:metabolism; D013119:Spinal Cord Injuries / Q000378:metabolism*; D013312:Stress, Physiological / Q000150:complications; D014363:Tryptamines / Q000652:urine
chemical_list: D000305:Adrenal Cortex Hormones; D014363:Tryptamines; C030820:tryptamine; D000324:Adrenocorticotropic Hormone; D003094:Collagen