An unusual pelvic tumor with benign glandular, sarcomatous, and Wilms' tumor-like components.
We present a pelvic tumor occurring in a 23 year old woman in which a Wilms' tumor-like element was predominant. The presence of a benign glandular component surrounded by small spindle and round malignant cells paralleled that encountered in adenosarcoma of the uterine body and cervix. The possible histogenesis is discussed. Clinically the recurrent tumor showed evidence of a response to chemotherapy. Treatment was complicated by petit mal seizures, for which adriamycin was responsible. The patient exhibited no evidence of disease 22 months after the first operation.
D000328:Adult; D002945:Cisplatin / Q000627:therapeutic use; D004317:Doxorubicin / Q000009:adverse effects / Q000627:therapeutic use; D004832:Epilepsy, Absence / Q000139:chemically induced; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008854:Microscopy, Electron; D010386:Pelvic Neoplasms / Q000628:therapy / Q000648:ultrastructure*; D009396:Wilms Tumor / Q000628:therapy / Q000648:ultrastructure*
D004317:Doxorubicin; D002945:Cisplatin