title: [Osteogenic sarcomas of the limbs. Radical treatment of the primary tumor: choosing between irradiation and amputation ].
abstract: In osteogenic sarcomas of the extremities, radical therapy of the primary tumor now seems more precisely delineated. In most cases, especially in large tumors with lytic lesions or fractures, and in children. Irradiation is indicated only in small tumors with condensation, and in tumors of the proximal metaphysis of the humerus. Conservative surgical treatment with carcinologically satisfactory resection of involved bone followed by reconstruction, is currently under evaluation. Such treatment is indicated in specific cases: children in the final stage of growth, and small tumors without major involvement of soft tissues that respond to preoperative chemotherapy.
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical / Q000379:methods*; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002648:Child; D004188:Disarticulation; D005121:Extremities / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D012516:Osteosarcoma / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*
vernacular_title: Sarcomes ostéogéniques des membres. Traitement radical de la tumeur primitive: le choix entre amputation et irradiation.