title: [Research on the occurrence of functional anomalies of the peripheral bronchi (small bronchi disease) in workers in a factory with respiratory noxious substances].
abstract: A group of 908 subjects has been studied, of which two-thirds were males, classified in 5 categories: unexposed, with light exposure, and severely exposed to inhalation of volatile substances, or various types of dust. A B.M.R.C. file was filled for each of the subjects. This file concerns respiratory symptoms. A forced expirogram was also performed, and FEV 25-75%, FEV 75-85%, and TEM were determined. The two expiratory flows (median and final) are frequently disturbed in subjects without respiratory symptoms, more frequently in smokers with a normal FEV 1. In those exposed to respiratory risk the proportion of alterations increases, but association of smoking with inhalation of noxious chemical substances will determine a modification of FEW 1 and anomalies of the peripheral bronchi occur more frequently in smokers. Between the criteria suggesting the presence of small airways disease, the ratio FEV 25-75% under 60%, with a FEV 1/FVC ratio within normal limits, this being the most sensitive of the criteria, also appears as the most reliable.
mesh_terms: D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects*; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001982:Bronchial Diseases / Q000209:etiology*; D004391:Dust; D005260:Female; D005740:Gases; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D009784:Occupational Diseases; D012906:Smoke; D013147:Spirometry
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D004391:Dust; D005740:Gases; D012906:Smoke
vernacular_title: Cercetări asupra frecvenţei anomaliilor funcţionale în bronhiile periferice (boala bronhiilor mici) la muncitorii dintr-o întreprindere cu noxe respiratorii.