Studies on antibodies reactive with glycoproteins of primate type C viruses in patients with myeloid leukemias and with potential preleukemia.
Human blood plasma from patients with myeloid leukemias, potentially preleukemic disorders and healthy individuals contains antibodies which react with purified glycoproteins of the baboon endogenous virus and the gibbon ape leukemia virus. Experiments are presented which illustrate characteristic distributions of antiviral antibodies in the plasma of different investigated groups. The presence of high-titer antibodies is associated with remission of acute myeloid leukemia and longer survival of patients with preleukemia.
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000276:immunology*; D010215:Papio; D011289:Preleukemia / Q000276:immunology*; D012190:Retroviridae / Q000276:immunology*; D014764:Viral Proteins / Q000276:immunology*
D000906:Antibodies; D006023:Glycoproteins; D014764:Viral Proteins