title: Active oxygen and medicine. Concluding remarks: a prospective view of active oxygen in medicine.
abstract: Factors are identified that influence the initiation, propagation, and efficiency of free-radical processes, or that ameliorate or mask them. Major biochemical disruptions of the ischemic myocardium or the central nervous system are cited for their underlying free-radical reactions. Encouraging attempts at rational therapy of disease having a free-radical component are referenced.
mesh_terms: D000818:Animals; D005609:Free Radicals; D006801:Humans; D010100:Oxygen / Q000502:physiology*; D013481:Superoxides
chemical_list: D005609:Free Radicals; D013481:Superoxides; D010100:Oxygen