title: [Effect of riodoxol on herpes simplex virus morphogenesis in experimental eye infection].
abstract: The effect of riodoxol on herpes simplex type 1 viruses was studied. It was shown to affect multiplication and maturation of the virus as manifested in the appearance of virions with incomplete nucleoid structure and long-term presence of virions in cytoplasmic vacuoles in cells. Submicroscopic changes suggest a dual effect of riodoxol on herpes simplex virus: on the DNA replicative cycle and on the stage of late maturation of virus at the time of its release from the nucleus.'
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D005123:Eye / Q000648:ultrastructure; D007635:Keratitis, Dendritic / Q000188:drug therapy* / Q000382:microbiology; D008854:Microscopy, Electron; D009024:Morphogenesis / Q000187:drug effects; D011817:Rabbits; D012118:Resorcinols / Q000627:therapeutic use*; D018139:Simplexvirus / Q000187:drug effects* / Q000648:ultrastructure
chemical_list: D000998:Antiviral Agents; D012118:Resorcinols; C031970:2,4,6-triiodoresorcinol
vernacular_title: Vliianie riodoksola na morfogenez virusa gerpesa prostogo pri éksperimetal'noĭ infektsii glaz.