Biochemical response of rat lung to inhaled n-hexane.
Biochemical response of the rat lung to inhaled n-hexane was investigated. Dose-dependent increase in protein, lipid, sialic acid, lactate dehydrogenase, angiotensin-converting enzyme, acid and alkaline phosphatase was observed in the cell-free lavage effluent of the lungs of exposed rats compared to the control animals. This was interpreted as enhanced pulmonary secretions accompanied by increased cell damage.
D000818:Animals; D006586:Hexanes / Q000633:toxicity*; D008168:Lung / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000032:analysis; D051381:Rats
D006586:Hexanes; D007703:Peptidyl-Dipeptidase A