Adenosine triphosphate synthesis coupled to K+ influx in mitochondria.
The influx of K+ into swollen mitochondria in the presence of valinomycin results in the synthesis of adenosine triphosphate in which approximately one H+ disappears per adenosine triphosphate synthesized. The synthesis is blocked by atractyloside but is insensitive to oligomycin and relatively insensitive to uncouplers.
D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000818:Animals; D000968:Antimycin A / Q000494:pharmacology; D001278:Atractyloside / Q000494:pharmacology; D003486:Cyanides / Q000494:pharmacology; D007473:Ion Channels / Q000502:physiology; D008928:Mitochondria / Q000378:metabolism*; D008933:Mitochondrial Swelling; D010766:Phosphorylation; D011188:Potassium / Q000378:metabolism*; D012402:Rotenone / Q000494:pharmacology; D014475:Uncoupling Agents / Q000494:pharmacology; D014634:Valinomycin / Q000494:pharmacology
D003486:Cyanides; D007473:Ion Channels; D014475:Uncoupling Agents; D012402:Rotenone; D001278:Atractyloside; D014634:Valinomycin; D000968:Antimycin A; D000255:Adenosine Triphosphate; D011188:Potassium