Control of intermediate lobe peptide secretion.
It appears that the intermediate lobe of the rat is able to process alpha-MSH, ACTH and endorphins from the precursor pre-opio-corticotrophin (31K). The release of these hormones is under a neural dopaminergic inhibitory control. A beta-adrenergic receptor mediating a stimulatory control, also appears to play a role in this release. The possible implications are discussed.
D000818:Animals; D004298:Dopamine / Q000502:physiology*; D010902:Pituitary Gland / Q000378:metabolism*; D010907:Pituitary Hormones / Q000378:metabolism*; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000502:physiology
D010907:Pituitary Hormones; D011943:Receptors, Adrenergic, beta; D004298:Dopamine