title: [Metoclopramide in hematology].
abstract: Metoclopramide is very useful in hematology. This French drug has been continuously used for twenty years as a powerful inhibitor of nausea and vomiting induced by numerous antineoplastic associations. When administered intravenously in patients under sequential chemotherapy for leukemia or lymphoma, metoclopramide prevents digestive discomfort. After each infusion, the ingestion of solution or tablets prolongs the antiemetic action for several hours without any side-effects. Conversely, corticosteroid therapy is well tolerated in ulcerous and gastritic patients and tolerance is preserved in others when they are submitted for the first time to high doses of metoclopramide, because of the acceleration of gastric evacuation.
mesh_terms: D006402:Hematologic Diseases / Q000188:drug therapy*; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use*
chemical_list: D008787:Metoclopramide
vernacular_title: A propos du métoclopramide en hématologie.