Cell surface T antigen in cells infected with simian virus 40 or an adenovirus-simian virus 40 hybrid, Ad2+D2.
Cell surface T antigen, detected by a radioimmune assay that uses 125I-labeled Staphylococcus aureus protein A and antibodies against either authentic T antigen or D2 hybrid T antigen, was found in simian virus 40-transformed and -infected cells and in cells infected with an adenovirus-simian virus 40 hybrid, Ad2+D2. In simian virus 40 lytic infection, the surface T antigen appeared at the same time as the nuclear T antigen.
D000260:Adenoviruses, Human / Q000235:genetics; D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D000957:Antigens, Viral, Tumor; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology*; D002467:Cell Nucleus / Q000276:immunology; D002472:Cell Transformation, Viral; D006824:Hybridization, Genetic; D051379:Mice; D013539:Simian virus 40 / Q000235:genetics / Q000276:immunology* / Q000502:physiology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000956:Antigens, Viral; D000957:Antigens, Viral, Tumor