title: Cervical papillomavirus infection in diethylstilbestrol-exposed progeny.
abstract: Histologic sections from cervical and vaginal biopsies showing dysplasia in 37 women exposed to diethylstilbestrol (DES) in utero were stained for human papillomavirus structural antigens using an immunoperoxidase technique. Forty-three percent of the lesions had detectable papillomavirus antigens. These findings indicate that a significant proportion of cervical dysplasia observed in DES-exposed progeny is associated with papillomavirus infection.
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D003218:Condylomata Acuminata / Q000276:immunology; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D027383:Papillomaviridae / Q000276:immunology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014412:Tumor Virus Infections / Q000276:immunology*; D002578:Uterine Cervical Dysplasia / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
chemical_list: D000956:Antigens, Viral; D004054:Diethylstilbestrol