Distribution and morphology of vasoactive intestinal polypeptide-like immunoreactive neurons in regio superior of the rat hippocampal formation.
The distribution and morphology of vasoactive intestinal polypeptide-like (VIP-L) immunoreactive neurons were studied in thick (70-120 microns) sections from the rat hippocampal formation using VIP antibody in combination with immunohistochemistry. Analysis of serial sections cut through the regio superior revealed a relatively dense aggregation of cells in stratum lacunosum-moleculare. Classification of cells in these (and other) layers on the basis of their morphology and orientation showed that hippocampal VIP-positive cells, unlike cortical ones, constitute a remarkably heterogeneous population. Studies of axonal trajectories of individual VIP cells showed that while some have local terminal arbors within the stratum lacunosum-moleculare close to the parent soma, other VIP cells send longer projections to other layers and subfields of the hippocampal formation.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D003712:Dendrites / Q000648:ultrastructure; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D006624:Hippocampus / Q000166:cytology*; D007124:Immunoenzyme Techniques; D008297:Male; D009474:Neurons / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D009435:Synaptic Transmission; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
D005768:Gastrointestinal Hormones; D014660:Vasoactive Intestinal Peptide