title: [Malignant fibrous histiocytoma of the bone].
abstract: The data of clinico-morphological study of 10 observations of malignant fibrous histiocytoma of the bone indicating its distinct nosological importance are presented. Clinico-morphological comparisons showed the typical variant of the morphological structure to have the worst prognosis. In two observations, the tumor was examined electron microscopically. All the 5 main types of cells were found: histiocyte- and fibroblast-like, giant multinuclear, xanthomatous, and poorly-differentiated mesenchymal. In one case, intranuclear virus-like inclusions of the herpesvirus type were found. Their presence in 4 main types of cells suggests their common histogenetic origin from poorly-differentiated mesenchymal cells.
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000648:ultrastructure; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology; D011859:Radiography
vernacular_title: Zlokachestvennaia fibroznaia gistiotsitoma kosti.