title: Catalysis of the disproportionation of superoxide by metalloporphyrins. III.
abstract: An assay based on the use of an oxygen electrode has been used to determine the superoxide dismutase-type activity of several metalloporphyrins. Both the iron(III) and manganese(III) derivatives of tetrakis-(4-N-methylpyridyl)porphine were shown to have comparable activity, about 2-3% of that of the enzyme. Comparisons are made between this assay method and the more standard one which depends on the conversion of nitroblue tetrazolium to formazan.
mesh_terms: D003300:Copper; D004492:Edetic Acid; D004566:Electrodes; D007501:Iron; D007700:Kinetics; D008345:Manganese; D008665:Metalloporphyrins; D010100:Oxygen; D013482:Superoxide Dismutase / Q000378:metabolism*; D013481:Superoxides
chemical_list: D008665:Metalloporphyrins; D013481:Superoxides; D008345:Manganese; D003300:Copper; D004492:Edetic Acid; D007501:Iron; D013482:Superoxide Dismutase; D010100:Oxygen