title: Fine structure and FSH binding of Sertoli cells in the blue fox (Alopex lagopus) in different stages of reproductive activity.
abstract: A clearly different Sertoli cell morphology was found in the immature blue fox and in the adults in and out of season. Immature cells had small, basally, located nuclei rich in peripheral heterochromatin, and few cytoplasmic organelles. Sertoli cells from adults in season had basally located, large, convoluted nuclei with homogenous nucleoplasma and prominent nucleoli. The basal and intermediate parts of the cytoplasm contained an extensively developed ER, numerous mitochondria, free ribosomes, lipid droplets and residual bodies, while the apical cytoplasm showed few distinct structures. In Sertoli cells from adults out of season the nuclei were dislocated towards the lumen, and apart from numerous dilated cisternae of ER, there were generally fewer organelles, but more glycogen particles. A marked rise in FSH binding was found towards the breeding season.
mesh_terms: D000375:Aging; D000818:Animals; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D005589:Foxes / Q000254:growth & development*; D008297:Male; D008854:Microscopy, Electron; D011956:Receptors, Cell Surface / Q000378:metabolism*; D011962:Receptors, FSH; D012708:Sertoli Cells / Q000378:metabolism* / Q000648:ultrastructure; D012741:Sexual Maturation
chemical_list: D011956:Receptors, Cell Surface; D011962:Receptors, FSH; D005640:Follicle Stimulating Hormone