Cytodiagnosis of herpes simplex virus infection in the newborn infant: report of a case.
Typical herpetic stomatitis that developed in a premature 6-day-old infant was initially diagnosed cytologically. The cytomorphologic characteristics of herpes simplex virus (HSV) infection in smears of scrapings from the oral mucosa helped to establish the diagnosis of a neonatal HSV infection, permitting early treatment with cytosine arabinoside (ara-C) and subsequent complete recovery from the generalized infection. The diagnosis was later confirmed by rises in the serologic titer of complement-fixing antibodies for HSV type 2.
D003581:Cytodiagnosis; D006561:Herpes Simplex / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D018139:Simplexvirus / Q000302:isolation & purification