Correlation between acetylcholine-evoked electrical activity, effect of cyclic AMP and actual redox state in frog rectus muscle.
In view of the very high correlation coefficient between actual redox state potential level in the biophase and spike activity--triggered by acetylcholine and influenced by cAMP--in skeletal muscles it seems rather reasonable the conclusion that the redox state potential level influences the cooperative effects not only in the case of acetylcholine but, directly, also the actions of cAMP, since the type of the regulatory influence of actual redox state potential level is non-additive in some cases, though additive in others.
D000109:Acetylcholine / Q000494:pharmacology*; D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology; D066298:In Vitro Techniques; D008751:Methylene Blue / Q000494:pharmacology; D009132:Muscles / Q000187:drug effects / Q000503:physiopathology*; D010084:Oxidation-Reduction; D011893:Rana esculenta; D013806:Theophylline / Q000494:pharmacology
D007093:Imidazoles; D013806:Theophylline; D000242:Cyclic AMP; D000109:Acetylcholine; D008751:Methylene Blue