title: Management of radiation ulcers.
abstract: Despite more efficient and safer technics of radiation therapy, the problem of radiation-induced injury to the skin and soft tissue persists. The problem of adequate coverage of these painful, ischemic, and fibrotic ulcers remains challenging. Split-thickness skin grafts are seldom sufficient coverage, as the graft almost always has areas that do not take. Although these areas may eventually heal by epithelialization, the result is never ideal. Most often flap coverage is required, but elevation of local flaps is jeopardized because the tissue surrounding the ulcer crater frequently has been sufficiently compromised to cause loss of at least part of the flap. In the past, this necessitated use of pedicled flaps, tubed and transposed from a distance. With the development of axial-pattern musculocutaneous and muscle flaps, as well as microvascular free flaps, the difficulty in dealing with these ulcers has been decreased. Surgeons can now recommend earlier use of adequate debridement, many times of the entire irradiated area, and immediate coverage with a well vascularized axial-pattern musculocutaneous flap or revascularized free flap.
mesh_terms: D000328:Adult; D000842:Ankle / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D002908:Chronic Disease; D003646:Debridement; D004407:Dysgerminoma / Q000532:radiotherapy; D006119:Groin / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000532:radiotherapy; D006801:Humans; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000601:surgery*; D012867:Skin / Q000098:blood supply; D012883:Skin Ulcer / Q000209:etiology / Q000601:surgery*; D013524:Surgical Flaps