title: Invasion of the lumen of the bile ducts by hepatocellular carcinoma.
abstract: The purpose of this investigation was to ascertain the prevalence and manifestations of tumorous invasion of the lumen of the bile ducts, a mode of local extension characteristic of hepatocellular carcinoma. In a series of 140 necropsied patients with hepatocellular carcinoma, tumorous invasion of the bile duct was noted in three patients (2.1%). Marked cholestasis was present in these three patients; the other manifestations related to the tumorous invasion of the bile duct were biliary pain in one and gall-bladder enlargement in two patients.
mesh_terms: D000368:Aged; D001652:Bile Ducts / Q000473:pathology*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology*; D002779:Cholestasis / Q000209:etiology; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness