Correlation between growth potential of mouse hepatitis viruses in macrophages and their virulence for mice.
Correlation between the virulence of mouse hepatitis virus (MHV) for mice and the growth potential of the virus in peritoneal adherent cells was observed for highly virulent MHV-2 and avirulent MHV-1, JHM, and MHV-S strains. However, this phenomenon was not observed in strain MHV-3, which multiplied to almost the same degree in peritoneal adherent cells from susceptible and resistant mouse strains.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D006524:Hepatitis, Viral, Animal / Q000276:immunology / Q000382:microbiology*; D008264:Macrophages / Q000276:immunology / Q000382:microbiology*; D051379:Mice; D006517:Murine hepatitis virus / Q000254:growth & development / Q000472:pathogenicity*