Dietary administration of eicosapentaenoic and linolenic acid increases arterial blood pressure and suppresses vascular prostacyclin synthesis in the rat.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D001792:Blood Platelets / Q000378:metabolism; D001794:Blood Pressure / Q000187:drug effects*; D004041:Dietary Fats / Q000494:pharmacology*; D015118:Eicosapentaenoic Acid; D011464:Epoprostenol / Q000096:biosynthesis*; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D008042:Linolenic Acids / Q000494:pharmacology*; D011453:Prostaglandins / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D013929:Thromboxane B2 / Q000097:blood; D013997:Time Factors; D017962:alpha-Linolenic Acid
D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated; D008042:Linolenic Acids; D011453:Prostaglandins; D017962:alpha-Linolenic Acid; D013929:Thromboxane B2; D015118:Eicosapentaenoic Acid; D011464:Epoprostenol