[Detection and mapping of conserved nucleotidic sequences between the genomes of human papillomavirus 1 a and bovine papillomavirus 1 by electron microscope heteroduplex analysis (author's transl)].
Three regions of partial homology have been detected between the genomes of human papillomavirus 1 a (HPV-1 a) and bovine papillomavirus 1 (BPV-1) by electron microscope analysis of heteroduplex molecules. These regions contain about 25% of non-homologous bases and represent 13% of the genome length. They have been mapped on the viral DNAs. This allowed a reciprocal orientation of the physical maps of the two genomes. Two regions are located in the middle of the transforming fragment of BPV-1 DNA and the third, at at diametrically opposite position, falls into the region of the genome coding most probably for a viral structural protein.
D000818:Animals; D052688:Bovine papillomavirus 1 / Q000235:genetics; D002417:Cattle; D002874:Chromosome Mapping; D004279:DNA, Viral; D006801:Humans; D008854:Microscopy, Electron; D009692:Nucleic Acid Heteroduplexes / Q000032:analysis*; D027383:Papillomaviridae / Q000235:genetics*
D004279:DNA, Viral; D009692:Nucleic Acid Heteroduplexes
Mise en évidence et localisation de régions conservées dans les génomes du papillomavirus human 1 a et du papillomavirus bovin 1 par analyse d'"hétéroduplex" au microscope électronique.