[Protective properties of theta-hemolysin obtained by affinity chromatography].
The data on the study of the protective activity of theta hemolysin and Cl. perfringens lecithinase preparations and the corresponding antitoxic sera obtained by indirect immune affinity chromatography are presented. Experiments in mice and guinea pigs indicate that the injection of antihemolytic serum and immunization with anatheta hemolysin ensures the protection of the animals from theta toxin. The enrichment of analecithinase preparation with anatheta hemolysin has been found to increase its protective properties against Cl. perfringens culture and toxin.
D000818:Animals; D001427:Bacterial Toxins / Q000276:immunology*; D002846:Chromatography, Affinity; D003016:Clostridium perfringens / Q000276:immunology; D005738:Gas Gangrene / Q000276:immunology / Q000517:prevention & control; D006168:Guinea Pigs; D006460:Hemolysin Proteins / Q000276:immunology* / Q000302:isolation & purification; D007106:Immune Sera / Q000276:immunology / Q000302:isolation & purification; D007110:Immunity, Active; D007116:Immunization, Passive; D051379:Mice; D014121:Toxoids / Q000276:immunology
D001427:Bacterial Toxins; D006460:Hemolysin Proteins; D007106:Immune Sera; D014121:Toxoids; C020452:Clostridium perfringens theta-toxin
Protektivnye svoĭstva téta-gemolizina, poluchennogo metodom affinnoĭ khromatografii.