The effect of indomethacin and its ester on lysosomal enzyme release from polymorphonuclear leukocytes and intracellular levels of cAMP and cGMP after phagocytosis of urate crystals.
D000242:Cyclic AMP / Q000097:blood; D006152:Cyclic GMP / Q000097:blood; D006801:Humans; D066298:In Vitro Techniques; D007213:Indomethacin / Q000031:analogs & derivatives / Q000494:pharmacology*; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology; D009712:Nucleotides, Cyclic / Q000097:blood*; D010587:Phagocytosis; D014527:Uric Acid / Q000378:metabolism
D009712:Nucleotides, Cyclic; D014527:Uric Acid; C018791:VUFB 12018; D000242:Cyclic AMP; D006152:Cyclic GMP; D007213:Indomethacin