Persistent cutaneous herpes simplex infection.
A 38-year-old, renal transplant patient developed painful, extensive, chancre-like genital ulcerations. The etiological agent was found culturally to be herpes virus type II. The eruption lasted five months and proved recalcitrant to standard therapeutic modalities. On removal of the transplanted kidney and thereby reduction of immunosuppressive agents, the cutaneous viral infection cleared rapidly. The potential severity and persistence of cutaneous herpetic infections in renal transplant patient must be well appreciated or the diagnosis might eaily be missed.
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects; D005260:Female; D006558:Herpes Genitalis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D011241:Prednisone / Q000009:adverse effects; D018139:Simplexvirus / Q000302:isolation & purification
D007166:Immunosuppressive Agents; D001379:Azathioprine; D011241:Prednisone