Evaluation and prediction of regenerative processes by quantitative analysis of the electromyographic response and biofeedback in peripheral nerve injuries.
The purpose of this study was to quantitatively and objectively evaluate and monitor regenerative processes in peripheral nerve lesions using a new electrophysiological method, and to develop and evaluate an electromyographic (EMG) biofeedback training programme for the rehabilitation of patients with such injuries. Five patients with traumatic unilateral brachial plexus injuries participated in the study longitudinally on a twice-weekly basis. The electrophysiological method was based on quantitative on-line analyses of the myoelectric signal from affected muscles of the upper limb. The biofeedback programme was developed and used to: (1) increase maximum voluntary centrally mediated neuromuscular activity; (2) dissociate desired and interfering neuromuscular activity; and (3) improve patient control over the neuromuscular activity. The electrophysiological results have differentiated clearly between muscles where regeneration can be assumed to be in progress and muscles where it is not in progress. This differentiation can be made prior to the occurrence of any observable contraction in muscle under study. The biofeedback training resulted in improved neuromuscular function in all patients.
D001917:Brachial Plexus / Q000293:injuries; D004576:Electromyography; D005246:Feedback; D006801:Humans; D009416:Nerve Regeneration; D059348:Peripheral Nerve Injuries; D010523:Peripheral Nervous System Diseases / Q000534:rehabilitation; D011379:Prognosis