[Double immunofluorescence detection of HBsAg and HBcAg in Councilman bodies of the liver].
It could be shown by double immune fluorescence methods that HBsAg and/or HBcAg were present in Councilman bodies of the liver as well as in normal hepatocytes in biopsy specimens of a patient with HBsAg-seronegative chronic active hepatitis. These findings support earlier observations, that HBsAg is deposited in necrotic liver cells, and it supports the hypothesis, that Councilman bodies are formed under the influence of virus.
D005455:Fluorescent Antibody Technique; D006509:Hepatitis B / Q000276:immunology / Q000473:pathology; D006512:Hepatitis B Core Antigens / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006521:Hepatitis, Chronic / Q000276:immunology / Q000473:pathology; D006801:Humans; D002479:Inclusion Bodies / Q000276:immunology*; D008099:Liver / Q000276:immunology* / Q000473:pathology; D009336:Necrosis
D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens
Doppelimmunfluoreszenzoptischer Nachweis von HBsAg und HBcAg in Councilman bodies der Leber.