title: [Inactivated vaccines against rhinopneumonitis in horses].
abstract: Attempts were made to produce inactivated vaccines against horse Herpes virus 1, using various inactivating agents and adjuvants, Best results were obtained with vaccine No 3 (glutaraldehide inactivator and "CTC" adjuvant). Used were two strains of the virus (St. Karaja and Varna). isolated in this country in cell cultures of a sucking pig kidney. Vaccine No 3 showed good immunogenic properties. Its application resulted in the full cease of abortions and respiratory diseases on the base of infection with the horse Herpes virus 1. The vaccination protects newborn colts from rhinopneumonitis if reimmunization of mares is carried out in the 6th-7th month of pregnancy.
mesh_terms: D000818:Animals; D004341:Drug Evaluation / Q000662:veterinary; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D005260:Female; D006168:Guinea Pigs; D006734:Horse Diseases / Q000517:prevention & control*; D006736:Horses; D010849:Picornaviridae / Q000276:immunology*; D010850:Picornaviridae Infections / Q000517:prevention & control / Q000662:veterinary*; D011247:Pregnancy; D012229:Rhinovirus / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines
vernacular_title: Inaktivirani vaksini sreshtu rinopnevmonita po konete.