Inhibitory activity of the new adamantane derivative N,N'-bis(ethylene)-P(1-adamantyl)-phosphonic diamide against Rous sarcoma virus.
A new adamantane derivative N,N'-bis (ethylene)P(1-adamantyl)-phosphonis diamide, was found to inhibit Rous sarcoma virus replication in much the same manner as reported for the parent compound, 1-adamantanamine hydrochloride.
D000218:Adamantane / Q000031:analogs & derivatives* / Q000494:pharmacology; D000327:Adsorption; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D001358:Avian Sarcoma Viruses / Q000187:drug effects* / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002472:Cell Transformation, Viral / Q000187:drug effects; D002642:Chick Embryo; D051381:Rats; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; C033959:N,N'-bis(ethylene)-P-(1-adamantyl)phosphonic diamide; D000218:Adamantane