A quantitative analysis of the Na+-dependence of Vmax of the fast action potential in mammalian ventricular myocardium. Saturation characteristics and the modulation of a drug-induced INa blockade by [Na+]o.
D000200:Action Potentials; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D004553:Electric Conductivity; D005260:Female; D006168:Guinea Pigs; D006321:Heart / Q000502:physiology*; D007473:Ion Channels / Q000187:drug effects*; D008297:Male; D011405:Propafenone; D011427:Propiophenones / Q000494:pharmacology; D012964:Sodium / Q000378:metabolism* / Q000502:physiology; D016276:Ventricular Function
D000779:Anesthetics, Local; D000889:Anti-Arrhythmia Agents; D007473:Ion Channels; D011427:Propiophenones; D011405:Propafenone; D012964:Sodium