title: ISR1: an insertion element isolated from the soil bacterium Rhizobium lupini.
abstract: The insertion element ISR1 was isolated from the soil bacterium R. lupini. In this strain, ISR1 shows a very strong affinity to plasmid RP4. It causes RP4 mutations at the strikingly high frequency of 10(-2) to 10(-1), either by the integration itself or by generating deletions. In E. coli, ISR1 seems to be inactive. No evidence could be obtained for a promoter site on ISR1 or for an ISR1-encoded protein. Our results indicate, however, an ISR1-specific termination signal for either transcription or translation.
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D002874:Chromosome Mapping; D004251:DNA Transposable Elements; D005786:Gene Expression Regulation; D005796:Genes; D009154:Mutation; D010957:Plasmids; D012231:Rhizobium / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements