Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini.
cDNAs coding for the amino and carboxy termini of two trypanosome variant surface glycoproteins (VSGs) have been sequenced. The results indicate that VSGs are synthesised with hydrophobic amino-terminal leader and carboxy-terminal tail sequences which are absent from purified mature VSGs.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D004262:DNA Restriction Enzymes; D005796:Genes; D014644:Genetic Variation; D006023:Glycoproteins / Q000235:genetics*; D008565:Membrane Proteins / Q000235:genetics*; D014346:Trypanosoma brucei brucei / Q000235:genetics*
D006023:Glycoproteins; D008565:Membrane Proteins; D004247:DNA; D004262:DNA Restriction Enzymes