Renal pseudotumour following treatment of Wilms' tumour.
A 9 1/2-year-old boy was found to have a mass occupying the lower pole of his left kidney, six years after his right kidney had been removed because of a Wilms' tumour. Investigation of the mass included angiography which demonstrated a mass with pathological arteries. Open biopsy of the mass revealed histological changes of nonspecific nephritis. It is probable that this nephritis was a result of radiation damage potentiated by concurrent treatment with actinomycin D, which he had received six years ago.
D000792:Angiography; D001706:Biopsy; D002648:Child; D003609:Dactinomycin / Q000009:adverse effects; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000528:radiation effects; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D009393:Nephritis / Q000209:etiology* / Q000473:pathology; D011832:Radiation Injuries; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000473:pathology; D009396:Wilms Tumor / Q000188:drug therapy / Q000532:radiotherapy*
D003609:Dactinomycin