Complete recovery of histiocytic medullary reticulosis-like syndrome in a child with acute lymphoblastic leukemia.
A 6-year-old boy with acute lymphoblastic leukemia (ALL) developed a haemophagocytic syndrome resembling histiocytic medullary reticulosis (HMR) but made a complete recovery on supportive treatment. This was subsequently found to have been associated with a parainfluenzal infection. It is suggested that HMR in immunocompromised hosts may represent a reactive process to an opportunistic viral infection and that the use of chemotherapy in these patients may be deleterious.
D002648:Child; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000188:drug therapy; D008206:Lymphatic Diseases / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D018184:Paramyxoviridae Infections / Q000150:complications; D013577:Syndrome
D007166:Immunosuppressive Agents