An open, multi-centre evaluation of a 5-day course of pivmecillinam in urinary tract infections in general practice.
One hundred and eleven general practice patients (101 females and 10 males) with acute uncomplicated cystitis received a 5-day course of pivmecillinam at a daily dose of 200 mg 3-times a day. Positive bacteriological cultures were found in 63 (57%) patients before treatment and three-quarters of all patients were totally symptom-free after treatment, with the post-treatment clinical symptom score falling by 94%. In those patients with a positive culture the bacteriological cure rate was 90%. Pivmecillinam was generally well tolerated. Side-effects were reported in 8 (7%) patients and only 1 of these patients had to stop treatment prematurely.
D000293:Adolescent; D000328:Adult; D000561:Amdinocillin Pivoxil / Q000009:adverse effects / Q000627:therapeutic use*; D001437:Bacteriuria / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010397:Penicillanic Acid / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D000561:Amdinocillin Pivoxil; D010397:Penicillanic Acid