[Hairy cell leukemia. II.--Critical review of literature. Part 2: the hairy cell origin (author's transl)].
Hairy cell leukemia (in french: leucémie à tricholeucocytes) is a distinctive form of chronic leukemia with splenomegaly, pancytopenia, presence of a particular circulating mononuclear cell, myelofibrosis and leukemic infiltration of the bone marrow. Generally, a tartrate resistant acid phosphatase activity is found in the leukemic cells. Hairy cell leukemia is the main leukemia in which the treatment is first surgical. Splenectomy has a good result for survival median and infectious risk. The disease is still mysterious for the origin of the leukemic cell; monocyte, B lymphocyte or in few cases T lymphocyte, even though a spectrum of immunological patterns pleads for the B lymphocyte origin of the leukemic cells.
D006801:Humans; D007943:Leukemia, Hairy Cell / Q000473:pathology*; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D009000:Monocytes / Q000276:immunology / Q000473:pathology
La leucémie à tricholeucocytes (hairy cell leukemia). II.--Revue critique de la littérature. 2e parite: origine du tricholeucocyte.