Lack of type C virus antibodies in systemic lupus erythematosus.
Twelve systemic lupus erythematosus (SLE) and 10 normal sera were similarly reactive in an assay for cytotoxic antibody to type C virus-infected and uninfected cells, but both were less cytotoxic for infected cells. Thus antibodies to type C viruses were not detected in SLE or normal sera, but type C infection may interfere with antibody recognition of other cell membrane antigens.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D003602:Cytotoxicity, Immunologic; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008297:Male; D011247:Pregnancy; D012190:Retroviridae / Q000276:immunology; D014412:Tumor Virus Infections / Q000276:immunology*
D000914:Antibodies, Viral