[Effect of prostaglandin E2, dexamethasone, and exertion on adrenocortical and sympathetic adrenal activity in dogs].
Influence of dexamethasone, prostaglandin E2 (PGE2) and physical load on activity of corticotropin, 11-oxycorticosteroids (11-OHCS), adrenaline, noradrenaline, glucose in arterial blood was studied in chronic experiment on dogs. A comparison with intact dog responses to exogenous PGE2 revealed an increase of corticotropin and 11-OHCS and a decrease of noradrenaline in arterial blood. Dexamethasone prevented adrenocortical activity in response to PGE2; it helped, however, to increase activity of noradrenaline.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000302:Adrenal Cortex / Q000502:physiology*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003907:Dexamethasone / Q000494:pharmacology*; D015232:Dinoprostone; D004285:Dogs; D004837:Epinephrine / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D008297:Male; D009638:Norepinephrine / Q000097:blood; D005082:Physical Exertion; D011458:Prostaglandins E / Q000494:pharmacology / Q000502:physiology*
D015062:11-Hydroxycorticosteroids; D001786:Blood Glucose; D011458:Prostaglandins E; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D015232:Dinoprostone; D009638:Norepinephrine; D004837:Epinephrine
Vliianie prostaglandina E2, deksametazoma i fizicheskoĭ nagruzki na adrenokortikal'nuiu i simpato-adrenalovuiu aktivnost' u sobak.