Production of superoxide by neutrophils.
Oxygen uptake by neutrophils has been stimulated by particulate serum-treated-zymosan (STZ) and soluble N-formylmethionyl-leucyl-phenylalanine (FMLP) in the presence and absence of the superoxide radical scavenger, cytochrome C. Results indicate that FMLP may stimulate neutrophils to produce superoxide but that STZ may not.
D001769:Blood; D002630:Chemotactic Factors; D003574:Cytochrome c Group / Q000494:pharmacology; D005260:Female; D006801:Humans; D009239:N-Formylmethionine / Q000031:analogs & derivatives / Q000494:pharmacology; D009240:N-Formylmethionine Leucyl-Phenylalanine; D009504:Neutrophils / Q000378:metabolism*; D009842:Oligopeptides / Q000494:pharmacology; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects; D013481:Superoxides / Q000378:metabolism*; D015054:Zymosan / Q000494:pharmacology
D002630:Chemotactic Factors; D003574:Cytochrome c Group; D009842:Oligopeptides; D013481:Superoxides; D009239:N-Formylmethionine; D009240:N-Formylmethionine Leucyl-Phenylalanine; D015054:Zymosan; D010100:Oxygen