Failure to confirm the role of immunological tolerance to B (MHC) alloantigens in the growth of RSV-induced tumours in chickens.
Chickens of the inbred "regressor" line CB (B12/B12) were made tolerant to the B13 (MHC) alloantigen of the congenic "progressor" line CC and then challenged with Prague strain of Rous sarcoma virus of subgroup C. No changes in tumour growth between tolerant and control groups were observed. These results suggest that there is no cross-reactivity between B13 alloantigen and RSV-induced tumour antigens.
D000818:Animals; D001358:Avian Sarcoma Viruses / Q000276:immunology*; D002645:Chickens; D007108:Immune Tolerance; D007519:Isoantigens / Q000276:immunology*; D001357:Sarcoma, Avian / Q000276:immunology*
D007519:Isoantigens