title: Membrane changes during viral infection.
abstract: The effect of viruses on the surface membrane of susceptible cells during the entry and exit process has been studied. Haemolytic paramyxoviruses induce a non-specific leakage to low-molecular-weight compounds during entry; other viruses do not show this effect. During exit, no such changes occur with any virus so far studied: some viruses are released without any obvious change at all in surface membrane function; in other cases, uptake of some nutrients is altered and there is a fall in membrane potential. These results do not support the hypothesis that a generalized membrane leakiness is a prerequisite for the synthesis and release of virus particles.
mesh_terms: D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology*; D002472:Cell Transformation, Viral; D006801:Humans; D008459:Measles virus / Q000235:genetics; D008564:Membrane Potentials; D009975:Orthomyxoviridae / Q000235:genetics; D010222:Parainfluenza Virus 1, Human / Q000235:genetics; D011188:Potassium / Q000378:metabolism; D012328:RNA Viruses / Q000235:genetics*; D012672:Semliki forest virus / Q000235:genetics; D013045:Species Specificity; D014721:Vesicular stomatitis Indiana virus / Q000235:genetics
chemical_list: D011188:Potassium