title: [Dynamics of the cyclic nucleotide content in the acute period of myocardial infarct].
abstract: Developing myocardial infarction is shown to be accompanied by raised plasma cAMP and cGMP levels which peak within the first few hours of the disease. Two patterns of changes were noted in the content of cyclic nucleotides: cAMP increase prevailing (a more typical pattern) and cGMP increase prevailing. Primary ventricular fibrillation was recorded in some patients belonging to the latter group. The development of cardiac failure is accompanied by a more stable rise of plasma cAMP.
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000097:blood; D003327:Coronary Disease / Q000097:blood; D000242:Cyclic AMP / Q000097:blood*; D006152:Cyclic GMP / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications; D013997:Time Factors
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP
vernacular_title: Dinamika soderzhaniia tsiklicheskikh nukleotidov v ostrom periode infarkta miokarda.