title: Brainstem auditory evoked responses in hereditary motor-sensory neuropathy: site of origin of wave II.
abstract: In three patients with hereditary motor-sensory neuropathy (HMSN), type I, brainstem auditory evoked responses (BAERs) showed prolongation of the latency of all major components. Interpeak latency I-III was prolonged, but the III-V interval was normal, and separation of waves I and II accounted for the prolonged I-III interval. Prolongation of I-II interval in this condition, which affects the peripheral nerves, preservation of wave II after cerebral death, and preservation of only waves I and II in the leukodystrophies suggest that wave II may be generated in the intracranial extramedullary portion of the eighth nerve.
mesh_terms: D000328:Adult; D001933:Brain Stem / Q000503:physiopathology*; D002648:Child; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology*; D012677:Sensation; D000159:Vestibulocochlear Nerve / Q000503:physiopathology