The same type of crystalline inclusions in T-lymphocytes as in plasma cells and B-lymphocytes in multiple myeloma. A pathological clone originating from a common lymphocyte stem cell?
2 patients with multiple myeloma had the same type of crystals in plasma cells, B-lymphocytes, and T-lymphocytes. It is hypothesized that these crystals are formed in cells belonging to the same clone of pathological cells. The clone would then have to be derived from a common lymphocyte stem cell.
D000368:Aged; D001402:B-Lymphocytes / Q000648:ultrastructure; D003460:Crystallization; D006412:Hematopoietic Stem Cells; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008214:Lymphocytes / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology*; D010950:Plasma Cells / Q000648:ultrastructure*; D013601:T-Lymphocytes / Q000648:ultrastructure