title: [Cytomegalovirus isolation in chronic salivary gland diseases of adults].
abstract: The results of virological investigation of a rare clinical instance of familial disease with a localized form of cytomegalovirus infection which, as a rule, is not diagnosed in life are presented. The infection localized in the salivary glands was the source of generalization of the process with a high fever, eruptions, lymphadenopathy, inflammatory changes in the excretory ducts of the salivary glands. Exacerbation of the chronic process was accompanied with high antibody titres (1:256--1:1024) with inhibition of the cellular immunity reactions in the mother. The latent form of infection in the father and two daughters ran without clinical manifestations, with low antibody titres and moderate inhibition of cellular reactions. The isolated strains of cytomegalovirus were identical in all the subjects under study and antigenically close to the Ad-169 strain.
mesh_terms: D000328:Adult; D000956:Antigens, Viral / Q000032:analysis; D002908:Chronic Disease; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000235:genetics / Q000276:immunology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000276:immunology / Q000382:microbiology; D012466:Salivary Gland Diseases / Q000235:genetics / Q000276:immunology / Q000382:microbiology*
chemical_list: D000956:Antigens, Viral
vernacular_title: Vydelenie tsitomegalovirusa pri khronicheskikh zabolevaniiakh u vzroslykh.