title: Enteritis in foals induced by rotavirus and enterotoxigenic Escherichia coli.
abstract: Colostrum-deprived, colostrum-fed or suckling foals were orally inoculated with foal rotavirus and enterotoxigenic Escherichia coli derived from a calf. Neither agent given alone caused diarrhoea in foals aged 1 or 2 days, although with rotavirus, 2 of the 3 inoculated foals became depressed 3 days after inoculation and all 3 were excreting rotavirus in the faeces. Inoculation of both agents induced diarrhoea in colostrum-deprived, colostrum-fed or suckling foals aged up to 16 days. There was an apparent age-related resistance to diarrhoea which developed between 2 and 3 weeks of age. It was related to failure of rotavirus to establish apparent infection in older foals and was independent of preinoculation maternal antibody.
mesh_terms: D000818:Animals; D003967:Diarrhea / Q000209:etiology / Q000662:veterinary; D004751:Enteritis / Q000209:etiology / Q000662:veterinary*; D004768:Enterotoxins / Q000633:toxicity*; D004926:Escherichia coli; D004927:Escherichia coli Infections / Q000150:complications / Q000662:veterinary*; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D012088:Reoviridae Infections / Q000150:complications / Q000662:veterinary*; D012401:Rotavirus
chemical_list: D004768:Enterotoxins