Effects of hypochlorite on thiamine and its derivatives.
Thiamine and its phosphorylated derivatives reacted with hypochlorite with reaction rates following the order: thiamine greater than thiamine monophosphate greater than thiamine diphosphate from pH 4.0 to 6.5. At least one unknown transient intermediate was formed and at least one non-thiochrome product was fluorescent. Chemiluminescence was also observed.
D006863:Hydrogen-Ion Concentration; D006997:Hypochlorous Acid; D007700:Kinetics; D008163:Luminescent Measurements; D013053:Spectrophotometry; D013831:Thiamine / Q000031:analogs & derivatives; D013833:Thiamine Monophosphate; D013835:Thiamine Pyrophosphate
D013833:Thiamine Monophosphate; D006997:Hypochlorous Acid; D013835:Thiamine Pyrophosphate; D013831:Thiamine