A study of the antiviral mechanism of action of 2-deoxy-D-glucose: normally glycosylated proteins are not strictly required for herpes simplex virus attachment but increase viral penetration and infectivity.
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D003837:Deoxy Sugars / Q000494:pharmacology*; D003847:Deoxyglucose / Q000494:pharmacology*; D004705:Endocytosis / Q000187:drug effects; D006023:Glycoproteins / Q000096:biosynthesis*; D006561:Herpes Simplex / Q000188:drug therapy*; D011092:Polyethylene Glycols / Q000494:pharmacology; D011991:Receptors, Virus / Q000187:drug effects; D018139:Simplexvirus / Q000187:drug effects; D014162:Transfection / Q000187:drug effects; D014764:Viral Proteins / Q000096:biosynthesis*; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D003837:Deoxy Sugars; D006023:Glycoproteins; D011991:Receptors, Virus; D014764:Viral Proteins; D011092:Polyethylene Glycols; D003847:Deoxyglucose