Stimulation of transepithelial sodium and chloride transport by ascorbic acid. Induction of Na+ channels is inhibited by amiloride.
D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D001693:Biological Transport, Active / Q000187:drug effects*; D002024:Bufo marinus; D002712:Chlorides / Q000378:metabolism*; D003315:Cornea / Q000378:metabolism; D004848:Epithelium / Q000187:drug effects / Q000378:metabolism; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism*; D007700:Kinetics; D011719:Pyrazines / Q000494:pharmacology*; D012964:Sodium / Q000378:metabolism*
D002712:Chlorides; D007473:Ion Channels; D011719:Pyrazines; D000584:Amiloride; D012964:Sodium; D001205:Ascorbic Acid