title: Inactivated bluetongue virus vaccine in lambs: differential serological responses related to breed.
abstract: A mixed breed flock of lambs, consisting of Suffolks, Hampshires, Columbias and Finnish breeds, were vaccinated with binary ethylenimine inactivated blue-tongue virus (BTV) serotypes 11, 17 and a mixture of 11 and 17 in aluminum hydroxide. Agar gel precipitin antibodies were used as an indicator of immunity. Sero-conversion of Hampshires and Suffolk lambs was poor at 43% as compared to 84% in the Columbia and Finn lambs. These results indicate a breed difference in immunological response to inactivated BTV vaccine.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001819:Bluetongue / Q000276:immunology; D001820:Bluetongue virus / Q000276:immunology*; D005260:Female; D008297:Male; D012087:Reoviridae / Q000276:immunology*; D012756:Sheep / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines