title: Anthracenedione activation by NADPH-cytochrome P-450 reductase; comparison with anthracyclines.
mesh_terms: D000818:Animals; D000873:Anthracenes / Q000378:metabolism*; D000880:Anthraquinones / Q000378:metabolism*; D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism*; D003630:Daunorubicin / Q000378:metabolism; D004317:Doxorubicin / Q000378:metabolism; D007700:Kinetics; D008862:Microsomes, Liver / Q000201:enzymology*; D008942:Mitoxantrone / Q000031:analogs & derivatives; D009245:NADH Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D009279:Naphthacenes / Q000378:metabolism; D011817:Rabbits; D013481:Superoxides / Q000378:metabolism
chemical_list: D000873:Anthracenes; D000880:Anthraquinones; D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D009279:Naphthacenes; D013481:Superoxides; D009249:NADP; D004317:Doxorubicin; D008942:Mitoxantrone; D003579:Cytochrome Reductases; D009245:NADH Dehydrogenase; C020182:ametantrone; D003630:Daunorubicin