The biphasic action of cardiac glycosides on the Na+, K+-pump and its relevance in the treatment of heart failure.
D000042:Absorption; D000818:Animals; D001665:Binding Sites; D002301:Cardiac Glycosides / Q000494:pharmacology*; D006168:Guinea Pigs; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D009200:Myocardial Contraction / Q000187:drug effects; D009206:Myocardium / Q000201:enzymology*; D010042:Ouabain / Q000494:pharmacology; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*; D013268:Stimulation, Chemical
D002301:Cardiac Glycosides; D007527:Isoenzymes; D010042:Ouabain; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium