title: Arthropathy in calcium pyrophosphate dihydrate crystal deposition disease. Pathologic study of 12 cases.
abstract: The pathologic features of calcium pyrophosphate crystal deposition disease (CPDD), particularly the synovial abnormalities, have not been adequately described or depicted in textbooks or journals; this report details the findings in 12 cases. Attention is drawn to the practical reasons for distinguishing CPDD arthropathy from other arthropathies, particularly osteoarthritis; clinical and gross pathologic features that should suggest CPDD arthropathy in cases that are not suspected preoperatively; and characteristics of the tophaceous deposits in CPDD.
mesh_terms: D000368:Aged; D001031:Apatites / Q000032:analysis; D001178:Arthroplasty; D001706:Biopsy; D002131:Calcium Pyrophosphate / Q000032:analysis; D002805:Chondrocalcinosis / Q000473:pathology; D011756:Diphosphates / Q000032:analysis; D005260:Female; D005528:Foot; D006225:Hand; D006801:Humans; D007592:Joint Diseases / Q000209:etiology / Q000473:pathology*; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000473:pathology; D013583:Synovial Membrane / Q000378:metabolism / Q000473:pathology*; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D011756:Diphosphates; D002131:Calcium Pyrophosphate