Possible involvement of parotid beta-adrenergic receptors in the etiology of sialadenosis.
The concentration of beta-adrenergic receptors was determined in rat and human parotid glands, in normal tissue as well as after sympathetic denervation of the rat, and in human sialadenosis. Receptor levels were clearly elevated after denervation of the rat and in sialadenosis. The possible implications of these findings for the etiology of human sialadenosis are discussed.
D000818:Animals; D003714:Denervation; D004082:Dihydroalprenolol / Q000378:metabolism; D005260:Female; D008565:Membrane Proteins / Q000378:metabolism; D010306:Parotid Gland / Q000294:innervation / Q000378:metabolism*; D051381:Rats; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000378:metabolism* / Q000502:physiology; D012798:Sialorrhea / Q000378:metabolism* / Q000503:physiopathology
D008565:Membrane Proteins; D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol