title: Addition of fiber (wheat bran, bassorin) to the standard food does not influence biliary lipid composition in piglets.
abstract: The influence of an additional fiber diet on biliary lipid composition of gallbladder bile was studied in 12 piglets. In addition to the standard feed wheat bran was given for 6 weeks and bassorin for 2 weeks to each of four piglets. A group of four piglets served as controls. Gallbladder bile was obtained by ultrasonically guided puncture of the gallbladder. The results showed no significant alteration of bile acids, lipid composition, and lithogenity of bile for either of the diets. These findings are interpreted in that way that the normally high basic fiber content of the food of piglets does not allow a further decrease of the lithogenic index by addition of wheat bran or bassorin. This conclusion would mean that the basic fiber diet should be known before therapeutic trials with fiber diets are planned or interpreted.
mesh_terms: D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000378:metabolism*; D004043:Dietary Fiber / Q000494:pharmacology*; D005704:Gallbladder / Q000378:metabolism; D050356:Lipid Metabolism; D013552:Swine; D014908:Triticum
chemical_list: D001647:Bile Acids and Salts; D004043:Dietary Fiber