title: Liver-fluke infection as an aetiological factor in bile-duct carcinoma of man.
abstract: This paper reviews, with particular reference to Opisthorchis viverrini, the evidence that opisthorchiasis and clonorchiasis are aetiological factors in the causation of human bile-duct cancer, especially cholangiocarcinoma, and considers the other aetiological factors which may be operating. The epidemiology, pathology in man and experimental animals, and histogenesis of cholangiocarcinoma associated wtih liver-fluke infection are also considered.
mesh_terms: D002759:Adenoma, Bile Duct / Q000209:etiology* / Q000473:pathology; D000818:Animals; D001650:Bile Duct Neoplasms / Q000209:etiology* / Q000473:pathology; D001652:Bile Ducts / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000209:etiology; D003003:Clonorchiasis / Q000150:complications* / Q000473:pathology; D006224:Cricetinae; D004032:Diet / Q000009:adverse effects; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000209:etiology; D009889:Opisthorchiasis / Q000150:complications* / Q000473:pathology