title: Assignment of the human phosphoserine phosphatase gene (PSP) to the pter leads to q22 region of chromosome 7.
abstract: Phosphoserine phosphatase (PSP) catalyzes the hydrolysis of phosphoserine to serine. PSP expression has been examined in human-mouse somatic cell hybrids retaining different combination of human chromosomes. Human PSP is expressed only when the pter leads to q22 segment of the human 7 and its enzyme marker beta-glucuronidase (GUSB) are retained in cell hybrids. The structural gene, PSP, is therefore assigned to this region of the human 7.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D002999:Clone Cells; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000502:physiology; D051379:Mice; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics*
chemical_list: D010744:Phosphoric Monoester Hydrolases; C022394:phosphoserine phosphatase