Modulation of epoxide hydrolase activity; effect on the activation of benzo[a] pyrene and its covalent binding to DNA in the nucleus.
D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000378:metabolism*; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism*; D002467:Cell Nucleus / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D004851:Epoxide Hydrolases / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D001580:Benzopyrenes; D002273:Carcinogens; D001564:Benzo(a)pyrene; D008748:Methylcholanthrene; D004247:DNA; D004851:Epoxide Hydrolases