title: [Adenosine-3',5'-phosphate, adenylate kinase, and cyclic AMP phosphodiesterase of the eye lens during aging].
abstract: Compared to other tissues, the level of cyclic adenosine 3',5' monophosphate (cAMP) of the whole eye lens, at all ages, is rather low. In the epithelial cell layer cAMP content is of the same order of magnitude as in brain tissue but decreases considerably with age. Adenylate cyclase activities measurable only in the epithelial cells diminishes with age. Reduction of cAMP phosphodiesterase activity is observed during aging in lens fibre cells.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000378:metabolism*; D000263:Adenylate Kinase / Q000378:metabolism*; D000375:Aging; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D007908:Lens, Crystalline / Q000201:enzymology / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D051381:Rats
chemical_list: D000242:Cyclic AMP; D010770:Phosphotransferases; D000263:Adenylate Kinase; D015105:3',5'-Cyclic-AMP Phosphodiesterases
vernacular_title: Adénosine 3' ,5' phosphate, adénylate cyclase, AMP cyclique phosphodiéstérase du cristallin au cours du vieillissement.