[Cis-platinum-induced peripheral neuropathy. One case (author's transl)].
A case of peripheral neuropathy secondary to cis-platinum therapy is reported. On the basis of electrophysiological studies and of biopsies, the predominantly sensory disorders observed (paraesthesias, pain, sensory ataxia) could be ascribed to axonal degeneration. This exceptional complication of cis-platinum therapy deserves to be borne in mind, since the drug is increasingly used, notably in genital cancers.
D000368:Aged; D001369:Axons / Q000473:pathology; D002945:Cisplatin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010525:Peripheral Nerves / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology
D002945:Cisplatin
Neuropathie périphérique au cisplatine. Une observation.