title: Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers.
abstract: Sera from 149 occupationally exposed toluene diisocyanate (TDI) workers were tested by RAST with p-tolyl monoisocyanate human serum albumin (TMI-HSA). Of the seven positives, one had a history suggestive of TDI asthma and one had a rash which may have been TDI related. These results indicate that false positive RAST with TMI-HSA may occur in asymptomatic workers.
mesh_terms: D001249:Asthma / Q000150:complications / Q000276:immunology; D003485:Cyanates / Q000276:immunology*; D003876:Dermatitis, Atopic / Q000276:immunology; D004342:Drug Hypersensitivity / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D005189:False Positive Reactions; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000096:biosynthesis; D017953:Isocyanates; D009784:Occupational Diseases / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D011852:Radioallergosorbent Test; D014051:Toluene 2,4-Diisocyanate / Q000276:immunology*
chemical_list: D003485:Cyanates; D017953:Isocyanates; D014051:Toluene 2,4-Diisocyanate; D007073:Immunoglobulin E; C025637:4-tolyl isocyanate