Hormonal changes in patients with haematological malignancies.
Levels of immunologically reactive insulin (IRI), growth hormone (GH), thyroxine, cortisol and ACTH in sera of patients with various haematological malignancies were determined. IRI and GH levels were increased in 80% of the patients regardless of the type of disease. IRI was more elevated in relapse than in remission. Cytostatic treatment returned IRI serum levels to normal. Thyroxine, ACTH and cortisol in serum were higher in only two percent of the patient with haematological malignancies.
D000208:Acute Disease; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006689:Hodgkin Disease / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007938:Leukemia / Q000097:blood*; D008223:Lymphoma / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood*; D013974:Thyroxine / Q000097:blood
D006728:Hormones; D007328:Insulin; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D013974:Thyroxine; D006854:Hydrocortisone