[Is a change in the microviscosity and asymmetrical distribution of phospholipids in the membrane a necessary condition for signal transmission? A comparison of the mechanisms of signal transmission in the plasma membranes of the brain synaptosomes and retinal photoreceptor membranes].
The localization of amino phospholipids (phosphatidyl ethanolamine, phosphatidyl serine) and their fatty acid composition in the outer and inner monolayers of plasma membranes from rat brain synaptosomes and retinal photoreceptors in the fish Theragra chalcograma have been studied by chemical modification. The mobility of the lipid components of these membranes was investigated by fluorescent and EPR spin probing techniques after transformation of outer (chemical and physical) signals. The data obtained are discussed in terms of molecular organization of the lipids and of the changes in the mobility of the lipid components of plasma membranes from brain synaptosomes and retinal photoreceptors during transmembrane transmission of the signal.
D000818:Animals; D001921:Brain / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D004578:Electron Spin Resonance Spectroscopy; D005399:Fishes; D005454:Fluorescence Polarization; D008563:Membrane Lipids / Q000502:physiology*; D010743:Phospholipids / Q000502:physiology*; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000502:physiology*; D009435:Synaptic Transmission; D013574:Synaptosomes / Q000502:physiology*; D014783:Viscosity
D008563:Membrane Lipids; D010743:Phospholipids
Iavliaetsia li izmenenie mikroviazkosti i asimmetrichnoe raspredelenie fosfolipidov v membrane obiazatel'nym usloviem peredachi signala? Sopostavlenie mekhanizmov peredachi signala v plazmaticheskikh membranakh sinaptosom mozga i fotoretseptornykh membranakh stechatki.