[The effect of combined radiotherapy on blood levels of ACTH, cortisol and aldosterone in cervical cancer].
Blood-ACTH, cortisol and aldosterone levels in patients with cancer of the uterine cervix were measured radioimmunologically prior to complex radiotherapy, following a half-dose exposure of tumor focus and immediately on completion of the treatment course. Patients showed a rise in cortisol and aldosterone levels and a slight increase in ACTH. Radiation therapy inhibited production of cortisol and aldosterone matched by a rise in ACTH output.
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D000450:Aldosterone / Q000097:blood*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008875:Middle Aged; D010913:Pituitary-Adrenal System / Q000503:physiopathology / Q000528:radiation effects; D011832:Radiation Injuries / Q000503:physiopathology*; D011879:Radiotherapy Dosage; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*
D000450:Aldosterone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Vliianie sochetannoĭ luchevoĭ terapii na soderzhanie AKTG, kortizola i al'dosterona v syvorotke krovi pri rake sheĭki matki.