[Isolation of enteroviruses from patients with clinical manifestations of poliomyelitis].
Examinations of 114 specimens (feces, nasopharyngeal washings, cerebrospinal fluid) from patients with clinical manifestations of poliomyelitis were carried out. Enteroviruses were isolated in 61.4% of the cases. Among the isolates, poliomyelitis viruses accounted for 49.1%, and Coxsackie B1 and ECHO 6 12.3%. Typing of the poliovirus isolates showed 17.9% to belong to type I, 7.1% to type II, and 75% to type III. Studies on intratypic differentiation revealed their antigenic similarity with the Mahoney, MEF-1, and Saukett strains, respectively. Among 24 paired blood sera tested for virus-neutralizing antibodies to wild poliovirus strains 21 demonstrated a 4-fold or higher rise of antibody titres to the above poliomyelitis viruses.
D000956:Antigens, Viral / Q000032:analysis; D002555:Cerebrospinal Fluid / Q000382:microbiology; D004770:Enterovirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D005243:Feces / Q000382:microbiology; D006801:Humans; D009305:Nasopharynx / Q000382:microbiology; D009500:Neutralization Tests; D011051:Poliomyelitis / Q000382:microbiology*; D012703:Serotyping
D000956:Antigens, Viral
Vydelenie énterovirusov ot bol'nykh s klinicheskimi proiavleniiami poliomielita.