title: Locust diuretic hormone-stimulated synthesis and excretion of cyclic-AMP: a novel Malpighian tubule bioassay.
abstract: Endogenous cyclic-AMP concentrations in Malpighian tubules of locusts increase as a result of diuretic hormone stimulation, and the level of increase is shown to be dependent on basal intracellular levels of cyclic-AMP. Furthermore, the increase in endogenous cyclic-AMP is in such excess as to cause excretion of high levels of cyclic-AMP in the urine.
mesh_terms: D000818:Animals; D001681:Biological Assay; D002988:Cloaca / Q000502:physiology*; D000242:Cyclic AMP / Q000096:biosynthesis / Q000378:metabolism*; D004231:Diuresis; D006110:Grasshoppers / Q000502:physiology*; D007301:Insect Hormones / Q000502:physiology*; D007700:Kinetics; D008297:Male; D008317:Malpighian Tubules / Q000502:physiology*
chemical_list: D007301:Insect Hormones; D000242:Cyclic AMP