Some dorsal raphe axons of the cat bifurcate to project into bilateral medial forebrain bundles.
Seventy-one dorsal raphe (DR) neurons of the cat were antidromically activated by electrical stimulation of the medial forebrain bundle (MFB). It was found that not a small number of DR neurons send their axons contralaterally. Seven out of 67 DR neurons (10.4%) responded to stimulation of both sides of MFB. Positive collision test for the bilaterally evoked responses indicates that single axons of these DR neurons bifurcate to innervate bilateral forebrain structures.
D000818:Animals; D001369:Axons / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology*; D002415:Cats / Q000502:physiology*; D004558:Electric Stimulation; D005071:Evoked Potentials; D005260:Female; D008297:Male; D008474:Medial Forebrain Bundle / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D011903:Raphe Nuclei / Q000502:physiology* / Q000648:ultrastructure; D011930:Reaction Time; D009435:Synaptic Transmission