Two types of intracytoplasmic inclusions in the cells of a patient with acute lymphoblastic leukemia.
A patient with acute lymphoblastic leukemia (ALL) with cells containing two types of cytoplasmic inclusions is described. The inclusions appeared as globular bodies containing electron dense material with homogeneous structure and as crystalloid formations confined in organelles with structure similar to that of the surrounding mitochondria. In distinction to other reports, these structures were not related to the endoplasmic reticulum. The possibility that some of them represented altered mitochondria is discussed.
D000208:Acute Disease; D000328:Adult; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007945:Leukemia, Lymphoid / Q000097:blood*; D008214:Lymphocytes / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron