title: Incidence of herpes simplex virus types 1 and 2 in penile lesions of college men.
abstract: Herpes simplex virus (HSV) was isolated from penile lesions of 15 college men. Using (E)-5-(2-bromovinyl)-2'-deoxyuridine sensitivity, monoclonal antibody immunofluorescence, and restriction endonuclease EcoRI digestion of viral DNA, 4 of 15 (26%) isolates were found to be HSV-1, and 11 of 15 (74%) isolates were found to be HSV-2. It is likely that some of the genital HSV-1 infections are related to oral genital contact, but this fact could not be established for all cases, since the females in this group had previously been shown to have a high incidence of genital HSV-1.
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D001973:Bromodeoxyuridine / Q000031:analogs & derivatives / Q000494:pharmacology; D004262:DNA Restriction Enzymes; D004279:DNA, Viral; D015246:Deoxyribonuclease EcoRI; D005260:Female; D006558:Herpes Genitalis / Q000382:microbiology*; D006801:Humans; D008297:Male; D010409:Penile Diseases / Q000382:microbiology*; D010413:Penis / Q000382:microbiology*; D018139:Simplexvirus / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D004279:DNA, Viral; C020235:brivudine; D004262:DNA Restriction Enzymes; D015246:Deoxyribonuclease EcoRI; D001973:Bromodeoxyuridine