Postulated effects of alterations in Na+,K+-ATPase on the pharmacokinetics and pharmacodynamics of digoxin.
D000328:Adult; D000367:Age Factors; D000368:Aged; D004077:Digoxin / Q000378:metabolism / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D000860:Hypoxia / Q000378:metabolism; D007223:Infant; D007477:Ions; D007676:Kidney Failure, Chronic / Q000378:metabolism; D007700:Kinetics; D008171:Lung Diseases / Q000378:metabolism; D011802:Quinidine / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013148:Spironolactone / Q000378:metabolism; D013959:Thyroid Diseases / Q000378:metabolism
D007477:Ions; D013148:Spironolactone; D004077:Digoxin; D000254:Sodium-Potassium-Exchanging ATPase; D011802:Quinidine