title: The pharmacology of hippocampal theta cells: evidence that the sensory processing correlate is cholinergic.
abstract: The firing repertoires of theta cells in the CA1 and dentate layers of the hippocampal formation of the freely moving rabbit were analyzed during 3 behavioral conditions: (1) voluntary motor patterns, termed type 1 theta behaviors; (2) automatic motor patterns, termed type 2LIA behaviors; (3) alert immobility with presentation of sensory stimuli, termed type 2 theta behavior. Cholinergic manipulations were shown to effect the firing repertoires of theta cells during the type 2 theta behavior condition (sensory processing) and not the other two behavioral conditions. A hypothesis of a sensorimotor processing function of the hippocampal formation is presented and discussed.
mesh_terms: D000818:Animals; D001143:Arousal / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects; D005071:Evoked Potentials / Q000187:drug effects; D006624:Hippocampus / Q000187:drug effects*; D009043:Motor Activity / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D010277:Parasympathomimetics / Q000494:pharmacology*; D011817:Rabbits; D011950:Receptors, Cholinergic / Q000187:drug effects*; D012677:Sensation / Q000187:drug effects*; D009435:Synaptic Transmission / Q000187:drug effects*; D013826:Theta Rhythm
chemical_list: D010277:Parasympathomimetics; D011950:Receptors, Cholinergic