The ocr+ gene function of bacteriophages T3 and T7 counteracts the Salmonella typhimurium DNA restriction systems SA and SB.
In host cells containing the Salmonella typhimurium DNA restriction-modification systems SA(+) and SB(+), replication of the ocr(+) bacteriophages T3 and T7 is not impaired. However, ocr (gene 0.3) mutants of these phages are susceptible to DNA restriction and modification by the SA(+) and SB(+) systems.
D004262:DNA Restriction Enzymes / Q000037:antagonists & inhibitors*; D004279:DNA, Viral / Q000378:metabolism; D005814:Genes, Viral; D012486:Salmonella typhimurium / Q000201:enzymology*; D013604:T-Phages / Q000235:genetics*; D014764:Viral Proteins / Q000235:genetics*; D014779:Virus Replication
D004279:DNA, Viral; D014764:Viral Proteins; C019077:anti-restriction proteins; D004262:DNA Restriction Enzymes