ESR investigations on the modification of the ascorbic acid-erythrocyte interaction by ferrous ions.
An ascorbic acid-erythrocyte interaction results in the formation of the semidehydroascorbate (SDA) radical and an increase in spin concentration. Addition of a more than ten-fold concentration of Fe2+ (as FeSO4) to such a system compensates the effect produced by ascorbic acid, that is the electron spin resonance spectrum obtained resembles very closely that of erythrocytes only. With the disappearance of the SDA radical a high spin ferric ion signal appears concomitantly at g = 4.3.
D001205:Ascorbic Acid / Q000097:blood*; D003683:Dehydroascorbic Acid / Q000031:analogs & derivatives / Q000097:blood; D004578:Electron Spin Resonance Spectroscopy; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005296:Ferrous Compounds / Q000494:pharmacology*; D005609:Free Radicals; D006801:Humans; D007501:Iron / Q000494:pharmacology*; D010084:Oxidation-Reduction
D005296:Ferrous Compounds; D005609:Free Radicals; C020748:ferrous sulfate; C000820:semidehydroascorbic acid; D007501:Iron; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid