Stress, ACTH, salt intake and high blood pressure.
Epidemiological evidence supports the thesis that high salt intake is involved in the aetiology of hypertension. If sodium intake is not causal, it appears other factors do not cause high blood pressure in unacculturated societies with low sodium intake. In this context, it is potentially important that stress causing ACTH release, as well as other neurohumoral effects, causes increased salt appetite and can impair renal sodium excretion.
D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D012964:Sodium / Q000378:metabolism; D012965:Sodium Chloride / Q000008:administration & dosage*; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology
D012965:Sodium Chloride; D000324:Adrenocorticotropic Hormone; D012964:Sodium