Treatment of complicated urinary tract infections with the long acting cephalosporin, ceftriaxone.
Ceftriaxone, a new broad spectrum cephalosporin with a long biological half-life has been used on a single intravenous daily dosage regimen over a five day period to treat complicated urinary tract infection. Bacteriological analysis of urine up to six weeks after such treatment, indicated that ceftriaxone was successful in 13 out of 15 cases treated compared with two out of 15 cases treated with cefuroxime given three times daily over the five day treatment period.
D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000652:urine; D002443:Ceftriaxone; D002511:Cephalosporins / Q000008:administration & dosage* / Q000652:urine; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011897:Random Allocation; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000652:urine
D002511:Cephalosporins; D002443:Ceftriaxone; D002439:Cefotaxime