Strength-duration curve: a measure for assessing sensory deficit in peripheral neuropathy.
By using an isolated constant current stimulator producing true square-wave pulses, sensory strength-duration curves were obtained at various sites by percutaneous electrical stimulation. Strength-duration curves derived from normal groups were compared to those of patients with peripheral neuropathy. Stimulus strength at sensory threshold was shown to be a reproducible measure of sensory deficit, increasing parallel to the degree of axonal failure found by conventional methods. This may be useful as a complementary method in assessing peripheral neuropathy.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000503:physiopathology; D003929:Diabetic Neuropathies / Q000503:physiopathology; D004558:Electric Stimulation; D005260:Female; D005267:Femoral Nerve / Q000503:physiopathology; D014890:Granulomatosis with Polyangiitis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D010525:Peripheral Nerves / Q000503:physiopathology*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D010543:Peroneal Nerve / Q000503:physiopathology; D012677:Sensation / Q000502:physiology*; D012684:Sensory Thresholds; D013497:Sural Nerve / Q000503:physiopathology; D009435:Synaptic Transmission; D014511:Uremia / Q000503:physiopathology