title: [Interaction of the polyene antibiotic nystatin with bivalent copper ions].
abstract: Characteristic features of interaction of nystatin with bivalent copper salts in water, methanol and dimethylsulfoxide were studied. It was shown that stable compounds of copper and nystatin at ratios of 1 : 2 and 1 : 4 formed in the above solvents. The antibiotic in these compounds was in an inert, native or activated state. Physicochemical and biological properties of the compounds were investigated.
mesh_terms: D001358:Avian Sarcoma Viruses / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003300:Copper / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D009980:Influenza A virus / Q000187:drug effects; D009761:Nystatin / Q000494:pharmacology; D010285:Pseudocowpox Virus / Q000187:drug effects
chemical_list: D009761:Nystatin; D003300:Copper
vernacular_title: Osobennosti vzaimodeĭstviia polienovogo antibiotika nistatina s ionami dvukhvalentnoĭ medi.