title: Obstructive uropathy: frusemide test and analysis of renographic curve patterns.
abstract: 49 patients with clinically proven uropathy and 14 others suffering from nephropathy underwent quantitative 131I-OIHA renography, combined with a frusemide provocation test. In significant obstruction, diuresis reaction was typically less than 5% (predictive value of a positive test 76%). The renographic curves, derived from the renal cortex and from the pyelon were diverging, with the pelvic curve showing a continuous rise (predictive value of a positive test for the curve pattern analysis 92%). Non-obstructive dilatation of the urinary system was characterized by a high diuresis index (greater than 15%) (predictive value 82%). The curve pattern was plateau-like before and showed a converging course of cortical and pelvic activity spontaneously, at least after diuresis provocation (predictive value 75%). Nephropathy alone could exceptionally mimick both significant obstruction and non-obstructive dilatation. Qualitative renographic curve analysis combined with diuresis provocation renders a higher diagnostic yield regarding the dynamic state of questionable uropathy than either test alone.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D005665:Furosemide; D006801:Humans; D007465:Iodohippuric Acid; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography; D004113:Succimer; D013667:Technetium; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D014570:Urologic Diseases / Q000175:diagnosis*
chemical_list: D007465:Iodohippuric Acid; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013667:Technetium; D005665:Furosemide; D004113:Succimer