[Carbonic anhydrase activity in male chronic alcoholics. Statistical analysis of correlations apropos of 74 cases].
Changes in cadmium blood levels and erythrocyte contents and in carbonic anhydrase activity (C.A.A.) were studied comparatively in 74 male subjects: 37 chronic alcoholics and 37 healthy age-matched controls. Chronic alcoholics exhibited significantly higher serum and erythrocyte cadmium concentrations and lower CAA than controls. Cadmium levels were correlated with the CAA. There was a negative correlation between the CAA and the mean corpuscular volume, daily alcohol intake and duration of the intemperance, in contrast with a positive correlation demonstrated for cadmium concentrations.
D000328:Adult; D000437:Alcoholism / Q000097:blood / Q000201:enzymology*; D002104:Cadmium / Q000097:blood; D002256:Carbonic Anhydrases / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged
D002104:Cadmium; D002256:Carbonic Anhydrases
Activité de l'anhydrase carbonique chez l'éthylique chronique de sexe masculin. Analyse statistique des corrélations à propos de soixante-quatorze observations.