[Iatrogenic colitis during flucytosine treatment for neuromeningeal cryptococcosis].
The authors report a case of colitis, with anatomo-clinical confrontation, during a treatment with flucytosine. In this fatal colitis, there were neither ulcerations nor pseudo-membranes. The histological data, with significant cytonuclear lesions, were consistent with a toxic-induced disorder of protein synthesis.
D003092:Colitis / Q000139:chemically induced*; D003453:Cryptococcosis / Q000188:drug therapy; D003596:Cytosine / Q000031:analogs & derivatives*; D005437:Flucytosine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008581:Meningitis / Q000188:drug therapy; D008875:Middle Aged
D003596:Cytosine; D005437:Flucytosine
Colite iatrogène au cours d'un traitement par la flucytosine pour cryptococcose neuroméningée.