title: [Action of ketoprofen on hepatic lysosomes in the rat].
abstract: Evidence for the stabilizing effect of ketoprofen on the lysosomal membrane is presented. Ketoprofen was as potent as indomethacin in stabilizing lysosomes subjected to changes in osmotic pressure. This effect was more marked in rats with adjuvant arthritis than in normal animals.
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000201:enzymology; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology; D007660:Ketoprofen / Q000494:pharmacology*; D008099:Liver / Q000648:ultrastructure; D008247:Lysosomes / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D010666:Phenylpropionates / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010666:Phenylpropionates; D007660:Ketoprofen; D007213:Indomethacin
vernacular_title: Action du kétoprofène sur les lysosomes hépatiques du rat.