title: [Metabolism of potassium and sodium when administered with different anions to patients with ischemic heart disease and arterial hypertension].
abstract: In 116 patients with coronary heart disease, essential hypertension, acute and chronic glomerulonephritis and pyelonephritis, the authors observed differences in the excretion of the ions of 42K, stable potassium, 24Na, stable sodium, chlorine as well as in the value of diuresis during the administration of equimolar solutions of potassium hydrocarbonate and potassium chloride, sodium hydrocarbonate and sodium chloride labeled with 42K and 24Na respectively. These differences depended on the expression of the basic (alkaline) characteristics of the anions of the administered solutions of potassium and sodium and the osmolarity of the administered amount of liquid. Pronounced ion exchange reactions were observed during the administration of KHCO3 solution only, the multiplicity factor of the excretion of sodium and chlorine ions with urine significantly exceeding that of diuresis. During the administration of KCl solutions in the isotonic NaCl solution and 5% glucose, the excretion of sodium and chlorine ions changed strictly in accordance with the changes of diuresis. Similar changes were noted in the administration of the solutions of sodium hydrocarbonate and sodium chloride.
mesh_terms: D001639:Bicarbonates / Q000008:administration & dosage; D003327:Coronary Disease / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D007275:Injections, Intravenous; D011188:Potassium / Q000378:metabolism*; D011189:Potassium Chloride / Q000008:administration & dosage; D017680:Potassium Compounds; D011197:Potassium Radioisotopes; D012964:Sodium / Q000378:metabolism*; D017693:Sodium Bicarbonate; D012965:Sodium Chloride / Q000008:administration & dosage; D012979:Sodium Radioisotopes; D012996:Solutions
chemical_list: D001639:Bicarbonates; D017680:Potassium Compounds; D011197:Potassium Radioisotopes; D012979:Sodium Radioisotopes; D012996:Solutions; D012965:Sodium Chloride; D011189:Potassium Chloride; D017693:Sodium Bicarbonate; D012964:Sodium; C026329:potassium bicarbonate; D011188:Potassium
vernacular_title: Obmen kaliia i natriia pri vvedenii ikh s razlichnymi anionami u bol'nykh ischemicheskoĭ bolezn'iu serdtsa i arterial'nymi gipertenziiami.