The met-enkephalin analog FK 33-824 directly inhibits ACTH release by the rat pituitary gland in vitro.
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D005405:D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; D004723:Endorphins / Q000494:pharmacology; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000494:pharmacology; D005260:Female; D066298:In Vitro Techniques; D008236:Lypressin / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D001615:beta-Endorphin
D004723:Endorphins; D009270:Naloxone; D008236:Lypressin; D004744:Enkephalin, Methionine; D001615:beta-Endorphin; D005405:D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; D000324:Adrenocorticotropic Hormone; D011388:Prolactin