title: Serum complement component depression during acute adenovirus conjunctivitis.
abstract: Serum C1q, C3, C4, and C5 components of complement levels were measured in 35 healthy subjects and 29 patients with acute conjunctivitis due to adenovirus type 2, 7, and 8 infections. Serum C1q and C3 levels were found to be significantly low, and there was no change in serum C4 and C5 levels. A progressive decline in the serum complement level with the severity of disease was observed. The change in the complement levels in serum showed a tendency to reach normal levels with clinical improvement.
mesh_terms: D000208:Acute Disease; D000257:Adenoviridae Infections / Q000276:immunology*; D000258:Adenovirus Infections, Human / Q000276:immunology*; D000328:Adult; D003166:Complement Activating Enzymes / Q000032:analysis; D015922:Complement C1q; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003182:Complement C5 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis*; D003231:Conjunctivitis / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D003176:Complement C3; D003181:Complement C4; D003182:Complement C5; D015922:Complement C1q; D003165:Complement System Proteins; D003166:Complement Activating Enzymes