title: Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 1 virus.
abstract: Vaccinated yearlings , two-year-old and in-foal pony mares with appropriate controls were exposed to aerosols of a subtype 1 virus one to two months after two or three vaccinations; all became infected. No obvious differences in the febrile responses, clinical signs and subsequent abortions were found between vaccinated and control mares. All vaccinated yearlings and two-year-old ponies developed a febrile respiratory disease but this was less severe than that suffered by the controls and the amounts and duration of virus shedding were reduced.
mesh_terms: D000034:Abortion, Veterinary / Q000517:prevention & control*; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D002986:Clinical Trials as Topic / Q000662:veterinary; D005260:Female; D006564:Herpesviridae / Q000276:immunology*; D006566:Herpesviridae Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D004861:Herpesvirus 1, Equid / Q000276:immunology*; D006734:Horse Diseases / Q000276:immunology* / Q000517:prevention & control*; D006736:Horses; D011247:Pregnancy; D014611:Vaccination / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology; D014766:Viremia / Q000517:prevention & control / Q000662:veterinary
chemical_list: D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines