Regional difference in the histamine-elicited accumulation of cyclic AMP in rabbit cerebral cortex with a cortical dominant focus.
A cortical dominant focus resulting in dominant spontaneous and stimulus-evoked flexions of the contralateral forelimb was formed by repeated, unilateral application of anodal current to the motor cortex in rabbits. Histamine-elicited accumulation of cyclic AMP was higher in cortical slices including the polarized point than in those of the contralateral area.
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D004292:Dominance, Cerebral / Q000187:drug effects*; D004558:Electric Stimulation; D005552:Forelimb / Q000294:innervation; D006632:Histamine / Q000494:pharmacology*; D009044:Motor Cortex / Q000187:drug effects* / Q000378:metabolism; D009119:Muscle Contraction / Q000187:drug effects; D009132:Muscles / Q000294:innervation; D011817:Rabbits
D006632:Histamine; D000242:Cyclic AMP