Granular cell myoblastoma in the tongue of a dog: a case report.
A granular cell myoblastoma was found in the dorsal side of the tongue of a 9-year-old female mongrel Pinscher. Macroscopically the tumour was white, well circumscribed, and 1 1/2 cm in diameter. Microscopically the tumour cells were arranged in small compact nests or cords with delicate, poorly vascularized collagen bundles in between. Acinar structures were found, also a few mitotic figures were present. Cytoplasmic granules showed a positive periodic acid Schiff reaction. Ultrastructural features included indented nuclei and small-sized vesicular cytoplasmic granules. The histogenesis of the neoplasm remains uncertain.
D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000648:ultrastructure / Q000662:veterinary*; D014059:Tongue / Q000648:ultrastructure; D014062:Tongue Neoplasms / Q000648:ultrastructure / Q000662:veterinary*