Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon.
Antibodies reactive with proteins of human T-cell leukemia virus (HTLV) can be found in Old World monkeys. A T-lymphocyte cell line established from a seropositive baboon (Papio cynocephalus) was analyzed for the presence of viral DNA sequences. The provirus found in these cells was related to but distinct from HTLV subgroup I. These results add to recent evidence from human studies that HTLV represents a spectrum of infectious T-lymphotropic retroviruses that includes closely and distantly related members.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology; D001483:Base Sequence; D002460:Cell Line; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis*; D017977:Deltaretrovirus / Q000235:genetics* / Q000276:immunology; D005814:Genes, Viral; D006801:Humans; D009693:Nucleic Acid Hybridization; D010215:Papio / Q000276:immunology / Q000382:microbiology*; D012091:Repetitive Sequences, Nucleic Acid; D013601:T-Lymphocytes / Q000032:analysis* / Q000382:microbiology
D000914:Antibodies, Viral; D000956:Antigens, Viral; D004279:DNA, Viral; D004262:DNA Restriction Enzymes