title: GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone.
abstract: Cytochrome oxidase activity and mitochondrial GDP binding were decreased in brown adipose tissue of mice treated chronically with corticosterone. These changes occurred both in corticosterone-treated mice fed ad libitum and in treated mice pair-fed to control animals. Although the dietary stimulation of brown-adipose-tissue thermogenesis was suppressed by corticosterone, the acute response to cold was not affected.
mesh_terms: D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D000818:Animals; D003080:Cold Temperature; D003345:Corticosterone / Q000494:pharmacology*; D003576:Electron Transport Complex IV / Q000378:metabolism; D005502:Food; D006150:Guanine Nucleotides / Q000378:metabolism*; D006153:Guanosine Diphosphate / Q000378:metabolism*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism
chemical_list: D006150:Guanine Nucleotides; D006153:Guanosine Diphosphate; D003576:Electron Transport Complex IV; D003345:Corticosterone