Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action.
D000328:Adult; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D005881:Gingiva / Q000201:enzymology*; D005883:Gingival Crevicular Fluid / Q000201:enzymology; D006801:Humans; D008297:Male; D003012:Microbial Collagenase / Q000378:metabolism*; D008911:Minocycline / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013754:Tetracyclines / Q000494:pharmacology*
D013754:Tetracyclines; D003012:Microbial Collagenase; D008911:Minocycline