Role of RecA protein spiral filaments in genetic recombination.
Physical and enzymatic studies on RecA protein from Escherichia coli provide the basis for a molecular model of general genetic recombination, a novel feature of which is the role attributed to spiral filaments of RecA protein.
D004247:DNA / Q000235:genetics; D004264:DNA Topoisomerases, Type I / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D046911:Macromolecular Substances; D008954:Models, Biological; D011485:Protein Binding; D011938:Rec A Recombinases / Q000502:physiology*; D011995:Recombination, Genetic; D013329:Structure-Activity Relationship
D046911:Macromolecular Substances; D004247:DNA; D011938:Rec A Recombinases; D004264:DNA Topoisomerases, Type I