Placental hormones: II. Immunofluorescence studies of the localization of prolactin/placental lactogen- and human chorionic gonadotrophin-receptors in human and rat placenta.
Human term placentae and rat placentae of gestation day 15 and 17 were examined for the localization of prolactin (PRL)/placental lactogen (PL) and human chorionic gonadotrophin (hCG) receptors by means of an immunofluorescence technique in order to determine possible target cells for PRL/PL and hCG and to obtain indirect evidence for the localization of steroid producing cells. In the human placenta, PRL/PL- and hCG-receptors were observed in the syncytiotrophoblast of the chorionic villi and in the giant cells of placental septa and cytotrophoblastic islands in the intervillous space. In the rat placenta, PRL/PL- and hCG-binding was localized mainly to the giant cells and vacuolated glycogen cells of the basal zone.
D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D005865:Gestational Age; D006801:Humans; D010920:Placenta / Q000032:analysis*; D011247:Pregnancy; D051381:Rats; D011956:Receptors, Cell Surface / Q000032:analysis*; D011974:Receptors, LH; D018000:Receptors, Peptide; D011981:Receptors, Prolactin
D011956:Receptors, Cell Surface; D011974:Receptors, LH; D018000:Receptors, Peptide; D011981:Receptors, Prolactin; C028202:placental lactogen receptor