Late irradiation-induced lesions of the lumbosacral plexus.
Lumbosacral plexus lesions developed in two women 8 and 14 years, respectively, after operation and irradiation for carcinoma of the uterus. In both patients, a left femoral nerve lesion was the presenting sign. The irradiation dose was about 5,000 rad on both sides in patient 1 and 8,400 rad on the affected side in patient 2. Both patients had low-frequency periodic discharges in the EMG.
D000328:Adult; D002277:Carcinoma / Q000532:radiotherapy; D005260:Female; D005267:Femoral Nerve; D006801:Humans; D008160:Lumbosacral Plexus; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D014594:Uterine Neoplasms / Q000532:radiotherapy