title: Nutrition in acute renal failure.
abstract: The nutritional value of regimes enriched with branched chain amino acids has been evaluated in 22 adult patients suffering from acute post-traumatic renal failure. The study was carried out for 12 days. The following data were recorded and compared daily: nitrogen balance, daily blood urea nitrogen (BUN), BUN/creatinine ratio, and plasma albumin levels. Also after 6 days of dialysis and nutritional support, the plasma medium molecular weight compounds (uremic toxins) were studied. It was concluded that: (a) the combined use of parenteral and oral nutrition appears most adequate in this type of patient; (b) the nitrogen intake should provide an essential amino acid/total nitrogen ratio of greater than or equal to 4 and a branched chain essential amino acid ratio of greater than or equal to 0.5; and (c) caution is still necessary in interpreting analyses of middle molecular weight compounds in this type of patient.
mesh_terms: D058186:Acute Kidney Injury / Q000178:diet therapy* / Q000209:etiology / Q000378:metabolism; D000328:Adult; D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage*; D001798:Blood Proteins / Q000032:analysis; D001806:Blood Urea Nitrogen; D002850:Chromatography, Gel; D006801:Humans; D008970:Molecular Weight; D009584:Nitrogen / Q000378:metabolism*; D014947:Wounds and Injuries / Q000150:complications
chemical_list: D000597:Amino Acids, Branched-Chain; D001798:Blood Proteins; D009584:Nitrogen