title: Transplacental transmission of bovine adenoviruses.
abstract: Type 1 bovine adenovirus has been isolated from cell cultures prepared from the kidneys of a 7-month-old bovine fetus, taken from a slaughterhouse, and types 4, 6 and 8 from cell cultures prepared from the testicles of four neonatal, precolostral calves. Sera of these precolostral calves possessed virus-neutralizing antibodies in titers of 1:4--1:16. Bovine adenoviruses of types 4 and 8 have also been isolated from two bovine fetuses aborted from an unknown cause. Relying upon these findings the possible vertical (transplacental) transmission of bovine adenoviruses is presumed. Though a cause-and-effect relationship between abortion and adenovirus infection could not be detected, it is probably that infection during fetal development cannot be indifferent to the fetus or the neonatal calf.
mesh_terms: D000034:Abortion, Veterinary / Q000209:etiology / Q000382:microbiology; D000256:Adenoviridae / Q000302:isolation & purification*; D000257:Adenoviridae Infections / Q000150:complications / Q000635:transmission* / Q000662:veterinary; D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology / Q000635:transmission*; D002478:Cells, Cultured; D005260:Female; D005333:Fetus; D007668:Kidney; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013737:Testis