Tumor seeding associated with bone marrow aspiration and biopsy.
A 53-year-old man with small-cell lung carcinoma underwent bone marrow aspirations and biopsies for tumor staging and harvest for autologous bone marrow infusion. Fourteen months after bone marrow aspiration and biopsy, a subcutaneous lesion grew over the posterior iliac crest, and a biopsy specimen disclosed small-cell carcinoma. To our knowledge, this is the first case report of tumor seeding associated with bone marrow aspirate and biopsy.
D001707:Biopsy, Needle / Q000009:adverse effects*; D001853:Bone Marrow / Q000473:pathology*; D001859:Bone Neoplasms / Q000556:secondary; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000556:secondary; D006801:Humans; D007085:Ilium; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009366:Neoplasm Seeding; D013997:Time Factors