title: Seroepidemiological survey of maedi-visna virus infection in sheep and goat flocks in Quebec.
abstract: Maedi-visna, a chronic viral disease of adult sheep characterized by progressive dyspnoea or neurological manifestations, was first recognized and described clinically in Canada in 1970. Seroepidemiological study was conducted in sheep and goats in various areas of Quebec. Sera of 10% of the animals of selected flocks were collected and specific antibodies against maedi-visna virus were tested by a modified direct complement fixation test. Results show seropositive rate of 67.6% for Sherbrooke sheep; of 40.5, 41.1 and 47.1% for Quebec, Saint-Hyacinthe and Nicolet sheep respectively and only 29.2 and 20.0% positive sera in l'Assomption and Rimouski animals. Prevalence rate of positive goats varied according to geographic areas (0 to 36.8%). Statistical analysis of various factors, e.g. age, breed, mode of raising, origin and size of flock showed no relation between these factors and the geographic areas. But, some clinical problems in the sheep flocks such as cough, rapid breathing, mortality and abortion were associated with high infection rate (greater than or equal to 50%) to maedi-visna virus. In goats, no correlation was demonstrated between these clinical signs and serological results. Our results suggest that it is important to consider this disease in an adequate program of preventive medicine in Quebec.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D003168:Complement Fixation Tests / Q000662:veterinary; D005260:Female; D006041:Goats / Q000276:immunology*; D008297:Male; D011021:Pneumonia, Progressive Interstitial, of Sheep / Q000453:epidemiology*; D011792:Quebec; D012756:Sheep / Q000276:immunology*; D014790:Visna-maedi virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral