Cloning of interleukin 2 mRNAs from human tonsils.
Human interleukin 2 (IL-2) mRNAs were cloned from a cDNA library prepared from mitogen-stimulated tonsillar mononuclear cells. One of these clones was sequenced and, using this cDNA as a hybridization probe, Southern blot analysis of the human placental DNA was performed. Our results indicate that there is only one IL-2 gene in the human genome.
D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism*; D004262:DNA Restriction Enzymes; D005796:Genes; D006801:Humans; D007376:Interleukin-2 / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D014066:Palatine Tonsil / Q000378:metabolism*; D010957:Plasmids; D012333:RNA, Messenger / Q000235:genetics*
D007376:Interleukin-2; D012333:RNA, Messenger; D004247:DNA; D004262:DNA Restriction Enzymes