Beta-endorphin immunoreactivity in the plasma of patients with the Prader-Labhart-Willi syndrome and their normal siblings.
No significant difference was found in the range or mean values of ir-beta-endorphin in the plasma of 6 patients with the Prader-Labhart-Willi syndrome compared to 7 of their normal siblings. The hypothesis that some of the symptoms of the P-L-W syndrome are due to excessive opioid activity is not supported by measurement of peripheral levels of ir-beta-endorphin.
D000293:Adolescent; D000328:Adult; D002648:Child; D004723:Endorphins / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011218:Prader-Willi Syndrome / Q000097:blood* / Q000235:genetics; D011863:Radioimmunoassay; D001615:beta-Endorphin
D004723:Endorphins; D001615:beta-Endorphin