Percutaneous treatment of pulmonary tumors by electrolysis.
Five lung tumors in four patients were treated with electrolysis. One of the tumors was probably primary, while the others were metastases. Under local anesthesia, two or three platinum electrodes (diameter 3 mm) were introduced through the thoracic wall into the lung tumor using biplane fluoroscopy. The patient was sedated before the procedure and a chest tube was inserted into the pleural cavity. Between anode and cathode a direct current of 80 mA and 10 V was passed during 2-4 h, creating substantial electrolytic destruction mainly through chlorine liberation. Observations at autopsy, surgery, chest X-ray, and CT showed that 60%-80% of the tumor mass was destroyed. No tumor was completely destroyed. The patients tolerated the procedure well.
D000230:Adenocarcinoma / Q000628:therapy; D006528:Carcinoma, Hepatocellular / Q000556:secondary / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000628:therapy; D004572:Electrolysis; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy*; D010610:Pharyngeal Neoplasms / Q000628:therapy; D012004:Rectal Neoplasms / Q000628:therapy