title: [Superoxide dismutase treatment of 2 cases of radiation-induced sclerosis].
abstract: Two patients with severe radio-induced necrosis were treated with bovine copper superoxide dismutase encapsulated in lysosomes (SOD). Two milligrams were injected subcutaneously every other day. This therapy was apparently effective on radio-induced inflammation and fibrosis. These are preliminary results that need confirmation. They suggest that SOD is useful, not only before radiation exposure, as a preventive, but also after exposure, as curative treatment for radiation injury.
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D011832:Radiation Injuries / Q000188:drug therapy*; D012598:Sclerosis / Q000188:drug therapy* / Q000209:etiology; D013482:Superoxide Dismutase / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D013482:Superoxide Dismutase
vernacular_title: Traitement par la superoxyde dismutase de deux cas de sclérose radio-induite.