title: [New contributions on extinction tests of essential headache. I. The test with lysine acetylsalicylate].
abstract: We report some preliminary results of a study carried out in ten patients observed during headache attack and concerning particularly the plasma values of beta-ELI after acetylsalicylic acid (lysini acetylsalicylas: i.v. 1.8 g) administration. Blood samples for beta-ELI determination were drawn every ten minutes for 30 minutes beginning at time of drug administration. Plasma was immediately separated and stored at -20 degrees C until assayed. Lysini acetylsalicylas administration gave in our subjects a significant relief from pain, with a disappearance of headache in all cases. We showed, in comparison with basal conditions, increased-plasma beta-ELI values after drug administration. The levels of pain were evaluated by the analogic visual scale.
mesh_terms: D000328:Adult; D000700:Analgesics; D001241:Aspirin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004723:Endorphins / Q000097:blood; D005260:Female; D006261:Headache / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008239:Lysine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D001615:beta-Endorphin
chemical_list: D000700:Analgesics; D004723:Endorphins; D001615:beta-Endorphin; D008239:Lysine; D001241:Aspirin; C010395:acetylsalicylic acid lysinate
vernacular_title: Nuovi contributi su le prove di estinzione nelle cefalee essenziali: I) Il test con acetilsalicilato di lisina.