Pivmecillinam for bacteriuria in pregnancy.
Pivmecillinam was given to 44 women with bacteriuria in pregnancy. Treatment was successful in 33 (87%) out of the 38 patients assessed. Thirty women subsequently received at random either a low-dose of pivmecillinam for up to three months or acted as a control group. Further bacteriuric episodes during pregnancy were recorded only in three patients in the control group. Thirty-nine out of the 41 women followed to term delivered healthy babies. One infant was stillborn and another child had a cleft palate. Neither was considered to be related to treatment with pivmecillinam.
D000293:Adolescent; D000328:Adult; D000561:Amdinocillin Pivoxil / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001437:Bacteriuria / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D002954:Citrobacter / Q000302:isolation & purification; D002986:Clinical Trials as Topic; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007709:Klebsiella / Q000302:isolation & purification; D010397:Penicillanic Acid / Q000627:therapeutic use*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D011292:Premedication; D011513:Proteus mirabilis / Q000302:isolation & purification; D011897:Random Allocation
D000561:Amdinocillin Pivoxil; D010397:Penicillanic Acid