Autoantibodies to brain specific proteins in human serum from normal and several pathological conditions.
Autoantibodies to three nervous tissue specific proteins [alpha Albumin (GFA, Eng et al., 1971), S100 (Moore et al., 1968) and MBP (Eylar et al., 1969)] were determined in sera from 270 neurological patients. Control values were established in sera from 21 blood donors. Differences between the control group and several pathological conditions were found, positive results were obtained in sera of patients affected with MS, polyneuropathy and astroglial tumors.
D001254:Astrocytoma / Q000175:diagnosis; D001323:Autoantibodies / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D001932:Brain Neoplasms / Q000175:diagnosis; D003704:Dementia / Q000175:diagnosis; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis; D009419:Nerve Tissue Proteins / Q000276:immunology*; D009422:Nervous System Diseases / Q000175:diagnosis*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis; D011863:Radioimmunoassay / Q000379:methods
D001323:Autoantibodies; D009419:Nerve Tissue Proteins