Cell surface proteins of rat myoblasts.
During the course of cell fusion of a rat myoblast cell line, L6, the relative amount of a cell surface protein of molecular weight (MW) 200 000-250 000 (L200), detected on the two-dimensional gel electrophoretogram, increases to one of a few major cell surface proteins in the older culture in which myotubes are being formed. In the non-fusing variant (M3A) of L6, such a spot is not detectable. Instead, one protein of MW 90 000-100 000 (M100) is found in large quantities in M3A, but in a small amount in L6. These results suggest the possibility that these cell surface proteins, particularly L200, may play a key role in the development of muscle cells.
D000818:Animals; D003012:Microbial Collagenase / Q000378:metabolism; D008970:Molecular Weight; D009132:Muscles / Q000166:cytology*; D009439:Neuraminidase / Q000378:metabolism; D011506:Proteins / Q000032:analysis*; D051381:Rats; D013499:Surface Properties
D011506:Proteins; D009439:Neuraminidase; D003012:Microbial Collagenase