Soft tissue responses to hydroxylapatite particles of different shapes.
Fifteen beagle dogs seven to 15 months of age had 0.5 g of hydroxylapatite in the form of sharp-edged particles (HA-1) or rounded particles (HA-2) implanted in buccal soft tissue pouches. Tissue specimens from each site were obtained at two weeks, six weeks, three months, and six months. A mild inflammatory response was seen at the implant sites with both particle shapes; however, inflammation resolved at a faster rate in the sites implanted with round hydroxylapatite particles.
D000818:Animals; D003757:Dental Implantation; D004285:Dogs; D017886:Durapatite; D005549:Foreign-Body Reaction / Q000473:pathology; D006097:Granulation Tissue / Q000033:anatomy & histology; D006882:Hydroxyapatites; D009061:Mouth Mucosa / Q000033:anatomy & histology*; D013280:Stomatitis / Q000473:pathology; D013499:Surface Properties
D006882:Hydroxyapatites; D017886:Durapatite