[Measurement of the reactivity of various types of white adipose tissue of rabbits to synacthene and isoproterenol].
The quantitative evaluation of lipolysis from different adipose deposits in the young rabbit shows that if the response to synacthen is equal to 1 (peristomachal tissue) that of the perirenal and periepididymal tissues would be 0.80 and that of the subcutaneous tissue would be 0.50. Comparatively isoproterenol (beta-adrenergic agonist) induces a lipolytic response which is equal to 0.19 for peristomachal and perirenal adipose tissues, 0.12 for the periepididymal tissue, and 0 for the subcutaneous tissue. Lipolytic efficiency is 600 times more important for synacthen than for isoproterenol whatever the anatomical origin of the adipose tissues is. Subcutaneous tissue, as a permanent mass, would have a thermic protection, while the other tissues, as transient reserves, are involved in the energetic disponibilities.
D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives*; D000818:Animals; D003366:Cosyntropin / Q000494:pharmacology*; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology*; D008066:Lipolysis / Q000187:drug effects; D008297:Male; D009928:Organ Specificity; D011817:Rabbits
D003366:Cosyntropin; D000324:Adrenocorticotropic Hormone; D007545:Isoproterenol
Mesure de la réactivité de différents tissus adipeux blancs du lapin au synacthène et à l'isoprotérénol.