title: Inactivation of measles and herpes simplex viruses by trypan blue.
abstract: The dye trypan blue inhibits infection of cells in tissue culture by measles and herpes simplex viruses at concentrations in excess of 0.01% (w/v) principally by direct inactivation of the virions. The inactivation is temperature-dependent (10(4) times greater at 37 degrees C than at 4 degrees C) and its mechanism appears to include inhibition of virus adsorption to cells.
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell; D002460:Cell Line; D002522:Chlorocebus aethiops; D006801:Humans; D007668:Kidney; D008459:Measles virus / Q000187:drug effects*; D018139:Simplexvirus / Q000187:drug effects*; D013696:Temperature; D014343:Trypan Blue / Q000633:toxicity*
chemical_list: D014343:Trypan Blue