Widespread occurrence in mammals of antibodies reactive to intracytoplasmic A particles of the mouse mammary tumor virus.
Serum antibodies reactive to clusters of intracytoplasmic A particles in mouse mammary tumors and leukemia cells by means of an indirect immunofluorescence assay were detected in 11 mammalian species (ranging in frequency from 5.1 to 29.3%). These antibodies could not be found in sera from chicken, ducks and geese. Their presence in so many mammalian species, not only in mammary tumor virus-infected mice, sheds new light on similar antibodies in man detected 10 years ago.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000032:analysis*; D000914:Antibodies, Viral / Q000032:analysis*; D002415:Cats; D002417:Cattle; D002645:Chickens; D006224:Cricetinae; D004285:Dogs; D004372:Ducks; D005455:Fluorescent Antibody Technique; D005777:Geese; D006041:Goats; D006168:Guinea Pigs; D006736:Horses; D008324:Mammary Tumor Virus, Mouse / Q000276:immunology*; D010455:Peptides / Q000276:immunology*; D011817:Rabbits; D051381:Rats; D012756:Sheep; D013045:Species Specificity; D013552:Swine
D000912:Antibodies, Neoplasm; D000914:Antibodies, Viral; D010455:Peptides