Transmission of adult T-cell leukemia virus from lymphoid cells to non-lymphoid cells associated with cell membrane fusion.
Transmission of adult T-cell leukemia virus (ATLV) was demonstrated from human lymphoid cell lines carrying ATLV to various non-lymphoid cells accompanied with syncytium formation, which was specifically inhibited by human anti-ATLV sera, indicating that ATLV has cell membrane fusion activity.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002415:Cats; D002459:Cell Fusion; D002460:Cell Line; D002472:Cell Transformation, Viral; D002522:Chlorocebus aethiops; D017977:Deltaretrovirus / Q000276:immunology / Q000472:pathogenicity*; D005455:Fluorescent Antibody Technique; D006367:HeLa Cells; D006801:Humans; D008214:Lymphocytes / Q000382:microbiology; D008251:Macaca; D051381:Rats; D012192:Retroviridae Infections / Q000635:transmission
D000956:Antigens, Viral