Effect of acute induced metabolic alkalosis on 800-m racing time.
Six trained middle-distance runners wer studied under alkalotic (NaHCO3 ingestion), placebo (CaCO3 ingestion), and control conditions to determine the effect of an acute induced metabolic alkalosis on time to run an 800-m race. Pre-exercise, following NaHCO3 ingestion, pH and standard [HCO3-] were significantly higher. In the alkalotic condition, subjects ran faster (2.9 s) and the corresponding post-exercise values for blood [lactate] and extracellular H+ were higher than in the control and placebo conditions, suggesting an increased anaerobic energy contribution. These results support the speculation that the increase in extracellular buffering following NaHCO3 ingestion facilitated H+ efflux from the cells of working muscle, thereby delaying the decrease in intracellular pH and postponing fatigue. It is concluded that the ingestion of NaHCO3 by trained middle-distance runners prior to an 800-m race has an ergogenic benefit.
D001639:Bicarbonates / Q000494:pharmacology*; D002119:Calcium Carbonate / Q000494:pharmacology; D004311:Double-Blind Method; D004734:Energy Metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D011897:Random Allocation; D012420:Running; D017693:Sodium Bicarbonate; D013997:Time Factors
D001639:Bicarbonates; D017693:Sodium Bicarbonate; D002119:Calcium Carbonate