[Effect of postsynaptic blockade of neuromuscular transmission on membrane properties of phasic muscle fibers in the frog].
Electric properties and acetylcholine sensitivity in frog sartorius muscle fibres were investigated after denervation and after prolonged paralysis with d-tubocurarine and alpha-bungarotoxin. No changes similar to those that appeared after nerve section developed in the muscle fibres after d-tubocurarine or alpha-bungarotoxin treatment. It is suggested that neurotrophic control of muscle fibres in frog is supported by materials transported to the muscle by axoplasmic flow rather than by the junctional acetylcholine or nerve impulsation.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004553:Electric Conductivity; D008564:Membrane Potentials; D009121:Muscle Denervation; D009132:Muscles / Q000294:innervation*; D009407:Nerve Block; D009469:Neuromuscular Junction / Q000502:physiology*; D011896:Rana temporaria; D012519:Sarcoplasmic Reticulum / Q000502:physiology*; D009435:Synaptic Transmission
D000109:Acetylcholine
Vliianie postsinaticheskoĭ blokady nervno-myshechnoĭ peredachi na svoista membrana faznykh myshechnykh volokon liagushki.