title: Relationship between cytological picture and hormone secretion by human pituitary adenomas in cell culture.
abstract: In 22 endocrinologically active hypophyseal adenomas the relationship between the biological behaviour and the cytological picture was investigated. There was a positive correlation between the atypia of the cells in the cytograms and hormone secretion of the tumour cells in vitro and the clinical aggressiveness. Cytological examination gave a better insight into the biological properties of these tumours than histological methods.
mesh_terms: D000236:Adenoma / Q000378:metabolism / Q000473:pathology*; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D046508:Culture Techniques; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D010911:Pituitary Neoplasms / Q000378:metabolism / Q000473:pathology*; D011388:Prolactin / Q000378:metabolism
chemical_list: D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013006:Growth Hormone