[Ouabain-sensitive respiration and Na K ATPase of the skeletal muscles and brown fat in cold-adapted rats].
Respiration of the neck muscles and brown adipose tissue of the rats increased as the rats adapted to cold in periodic regimen. The ouabain--sensitive component of the neck muscles respiration did not increase while increasing in the brown adipose tissue. Activity of Na, K-ATPase of the neck and thigh muscles was reduced while increasing in the brown adipose tissue. Sensitivity of Na, K-ATPase of the skeletal muscles to the acetylcholine inhibitory effect considerably increased in the period of cold adaptation. The findings do not confirm assumption of Na--pump involvement in the activation of nonshivering thermogenesis in the skeletal muscles in cold adaptation.
D000064:Acclimatization; D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001833:Body Temperature Regulation; D003080:Cold Temperature; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D010042:Ouabain; D000254:Sodium-Potassium-Exchanging ATPase
Uabain-chuvstvitel'noe dykhanie i Na, K-ATFaza skeletnykh myshts i burogo zhira u adaptirovannykh k kholodu krys.