title: [Potential reserve capabilities of the adenohypophyseal-adrenal cortex system in children with thymus hyperplasia and prospects for treatment].
abstract: The potentialities of the adrenocortical system and thymic condition after corticotropin use were studied in young children with thymic hyperplasia combined with pneumonia. The results of the hormonal status studies after zinc-corticotropin suspension load indicate the secondary adrenocortical hypofunction. Corticotropin use within 5 to 10 days in a dose of 1 E/kg body weight intramuscularly is adequate to obtain the thymic involution in thymomegaly.
mesh_terms: D000302:Adrenal Cortex / Q000503:physiopathology*; D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010903:Pituitary Gland, Anterior / Q000503:physiopathology*; D010912:Pituitary-Adrenal Function Tests; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D011014:Pneumonia / Q000150:complications / Q000503:physiopathology; D013952:Thymus Hyperplasia / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D000324:Adrenocorticotropic Hormone
vernacular_title: Potentsial'nye rezervnye vozmozhnosti sistemy adenogipofiz-kora nadpochechnikov u deteĭ s timomegalieĭ i perspektivy lecheniia.