title: Malignant fibrous histiocytoma arising in previous surgical sites. Report of two cases.
abstract: Two patients who developed malignant fibrous histiocytoma in previous surgical sites are reported. One patient developed malignant fibrous histiocytoma in an amputation site, and the other patient developed it in a previous hernioplasty scar. Both patients presented with a mass, clinically interpreted as a subcutaneous abscess. The light microscopic and fine structural features of these tumors are described. A possible causal relationship between previous surgery and malignant fibrous histiocytoma is discussed in view of other reported cases arising in various conditions following chronic reparative reactions.
mesh_terms: D000328:Adult; D000368:Aged; D000672:Amputation Stumps; D002921:Cicatrix / Q000473:pathology*; D006547:Hernia; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure