[Features of ion currents induced by acetylcholine in the muscle fibers of the lamprey].
Spontaneous miniature end-plate currents (MEPC) and acetylcholine-induced noise were recorded in muscle fibres of m. longitudinalis linguae of lamprey. The MEPC decay time constant was 5.3 ms and amplitude 2.2 nA. The mean channel life time was 3.6 ms and conductance 13.6 pS. Ionic channels in synaptic and extrasynaptic zones had identical kinetics. Inhibition of acetylcholinesterase induced a 2.2-fold prolongation of MEPC, but did not affect the channel life time.
D000109:Acetylcholine / Q000494:pharmacology*; D000110:Acetylcholinesterase / Q000502:physiology; D000818:Animals; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects*; D007798:Lampreys; D008564:Membrane Potentials / Q000187:drug effects; D009045:Motor Endplate / Q000187:drug effects; D009132:Muscles / Q000187:drug effects* / Q000201:enzymology; D009469:Neuromuscular Junction / Q000187:drug effects*; D013570:Synaptic Membranes / Q000187:drug effects
D007473:Ion Channels; D000110:Acetylcholinesterase; D000109:Acetylcholine
Osobennosti ionnykh tokov, vyzyvaemykh atsetilkholinom v myshechnykh voloknakh minogi.