title: Glandular intraepithelial neoplasia (GIN)--a unifying concept of the precursors of endometrial adenocarcinoma.
abstract: There is considerable variation and a good deal of confusion surrounding definitions and nomenclature for premalignant lesions of the endometrium. A unifying concept, based on the model of cervical intraepithelial neoplasia, is proposed to provide a uniform, practical basis for the diagnosis and management of the precursors of endometrial cancer. Lesions would be classified as glandular epithelial neoplasia (GIN) Grades, 1, 2 and 3. Illustrated examples, and comparisons with other classifications are provided.
mesh_terms: D000230:Adenocarcinoma / Q000145:classification* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000145:classification* / Q000175:diagnosis / Q000473:pathology; D009626:Terminology as Topic; D014594:Uterine Neoplasms / Q000145:classification* / Q000175:diagnosis / Q000473:pathology