title: [In-vitro activity of cefotaxime].
abstract: From 1979 to 1982, a large number of freshly isolated strains of bacteria were investigated at our institute with regard to their sensitivity to cefotaxime in comparison to other antibiotics. The isolates came from 42 clinics in the Rhine-Main region. The results of the investigations demonstrate that cefotaxime, due to its high stability against beta-lactamases, has advantages over to older cephalosporins, and even cefoperazon and cefoxitin. Despite increased use of cefotaxime, there was no change in the sensitivity of the organisms from 1979 to 1982.
mesh_terms: D002439:Cefotaxime / Q000627:therapeutic use*; D002440:Cefoxitin / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D004755:Enterobacteriaceae / Q000187:drug effects; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009070:Moxalactam / Q000627:therapeutic use; D010403:Penicillin Resistance; D010406:Penicillins / Q000627:therapeutic use; D013290:Streptococcal Infections / Q000188:drug therapy; D013291:Streptococcus / Q000187:drug effects
chemical_list: D002511:Cephalosporins; D010406:Penicillins; D002440:Cefoxitin; D002439:Cefotaxime; D009070:Moxalactam
vernacular_title: Die In-vitro-Aktivität von Cefotaxim.