Two protein-binding sites in chromatin implicated in the activation of heat-shock genes.
The resistance to exonuclease digestion of two regions of chromatin at the 5' end of heat-shock genes in Drosophila implies they have protein bound to them. The pattern of resistance before and after induction of gene expression suggests that heat-shock genes are activated by the sequential binding of at least two protein factors.
D000818:Animals; D001483:Base Sequence; D002843:Chromatin / Q000502:physiology / Q000648:ultrastructure*; D004268:DNA-Binding Proteins / Q000502:physiology; D003851:Deoxyribonucleases; D004331:Drosophila melanogaster / Q000235:genetics; D005092:Exonucleases; D005786:Gene Expression Regulation; D005796:Genes; D006360:Heat-Shock Proteins / Q000235:genetics*; D009876:Operon
D002843:Chromatin; D004268:DNA-Binding Proteins; D006360:Heat-Shock Proteins; D003851:Deoxyribonucleases; D005092:Exonucleases