title: Developmental change in choline acetyltransferase activity in nerve endings of latissimus dorsii muscles in the chick embryo: influence of chronic spinal cord stimulation.
abstract: Choline acetyltransferase (CAT) activity of chick latissimus dorsii muscles was studied during embryonic development and at post-hatching states. CAT activity was always higher in anterior (ALD) than in posterior (PLD) muscles. At embryonic stages, chronic spinal cord stimulation at a low rhythm did not modify CAT activity in ALD nerve endings but caused a transient increase in PLD terminals. This increase in CAT activity seems to be related to an acceleration of neuronal maturation rather than to the occurrence of the multiple innervation that results from the central stimulation.
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D004558:Electric Stimulation; D009046:Motor Neurons / Q000166:cytology; D009132:Muscles / Q000294:innervation*; D009469:Neuromuscular Junction / Q000166:cytology*; D013116:Spinal Cord / Q000502:physiology*; D009435:Synaptic Transmission
chemical_list: D002795:Choline O-Acetyltransferase; D000109:Acetylcholine