The effect of dietary protein levels on diet-induced thermogenesis in the rat.
Relative to rats fed a 15% protein-diet, 300-g rats fed a 5% protein-diet for 5 weeks consumed 19% more food but gained only 28% as much weight, showed twice the thermic response when fed, had twice as much subscapular brown adipose tissue with almost twice the specific GDP-binding activity. There was no difference between these groups in skeletal growth nor, unexpectedly, in the proportion of carcass fat.
D000273:Adipose Tissue / Q000033:anatomy & histology; D002001:Adipose Tissue, Brown / Q000033:anatomy & histology / Q000502:physiology*; D000818:Animals; D001823:Body Composition / Q000187:drug effects; D001833:Body Temperature Regulation / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D002364:Caseins / Q000008:administration & dosage*; D004247:DNA / Q000378:metabolism; D004032:Diet; D004305:Dose-Response Relationship, Drug; D004734:Energy Metabolism; D019204:GTP-Binding Proteins; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D011956:Receptors, Cell Surface / Q000378:metabolism*
D002364:Caseins; D011956:Receptors, Cell Surface; D004247:DNA; D019204:GTP-Binding Proteins