title: The speciation of plutonium in foodstuffs and its influence on gut uptake.
abstract: Soluble plutonium complexing agents in foodstuffs have been identified. These have been labelled to high specific activity with 238Pu and their gut uptake determined in rats. The range of values found for naturally-occurring complexes was between 0.03% for oxalate and 0.1% for phytate. However, reasons are advanced for believing that the enhancement of uptake in rats fed the phytate complex would not be expected to occur in man. These results are not taken, therefore, as suggesting that there should be any change in the gut uptake factor of 0.05% currently recommended by the National Radiological Protection Board for plutonium contained in foodstuffs eaten by humans.
mesh_terms: D010832:6-Phytase / Q000378:metabolism; D017766:Acid Anhydride Hydrolases; D000818:Animals; D002951:Citrates; D005260:Female; D005507:Food Contamination, Radioactive; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000201:enzymology; D009566:Nitrates; D009942:Organometallic Compounds; D010070:Oxalates / Q000378:metabolism; D019815:Oxalic Acid; D010215:Papio; D010710:Phosphates / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D010833:Phytic Acid / Q000378:metabolism; D011005:Plutonium / Q000378:metabolism*; D011122:Polyphosphates / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D014675:Vegetables / Q000032:analysis
chemical_list: D002951:Citrates; D009566:Nitrates; D009942:Organometallic Compounds; D010070:Oxalates; D010710:Phosphates; D011122:Polyphosphates; C015459:plutonium nitrate; D011005:Plutonium; D010833:Phytic Acid; C036636:plutonium phytate; D019815:Oxalic Acid; D010744:Phosphoric Monoester Hydrolases; D010832:6-Phytase; D017766:Acid Anhydride Hydrolases; C022563:endopolyphosphatase; C009293:trimetaphosphoric acid; C009285:sodium polymetaphosphate