Cholinergic stimulation of hippocampal pyramidal cells is inhibited by increasing membrane cholesterol.
D000818:Animals; D002217:Carbachol / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism*; D046508:Culture Techniques; D005071:Evoked Potentials / Q000187:drug effects; D006624:Hippocampus / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013570:Synaptic Membranes / Q000187:drug effects / Q000378:metabolism*; D009435:Synaptic Transmission / Q000187:drug effects*
D002217:Carbachol; D002784:Cholesterol