title: Extravasation of pertechnetate in cranial extracerebral tissues during first pass across the cerebral vasculature.
abstract: By evaluating regional cerebral first pass curves following Pertechnetate administration in common, internal and external carotid artery, it has been shown that about 20% of the injected dose of Pertechnetate extravasates in cranial extracerebral tissues during the first pass. This extravasation may lead to an overestimation of about 1 sec in the determination of regional cerebral mean transit time by intravenous radionuclide Angiography.
mesh_terms: D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D013667:Technetium / Q000378:metabolism*
chemical_list: D013667:Technetium; D013670:Sodium Pertechnetate Tc 99m