title: Treatment of hilar carcinoma by bile drainage combined with internal radiotherapy using 192iridium wire.
abstract: Eighteen patients with a cholangiocarcinoma involving the hilum of the liver, and one patient with a carcinoma of the gall bladder causing obstruction of the common hepatic duct, have been treated with bile drainage using a U-tube (8 patients) or a percutaneous transhepatic catheter (11 patients) followed by internal radiotherapy with 192iridium wire. The median survival is 11 months, and 9 patients (47 per cent) have survived for 12 months or longer. The addition of internal radiotherapy may be beneficial to patients with hilar cholangiocarcinoma causing biliary obstruction in whom bile drainage can be established.
mesh_terms: D002759:Adenoma, Bile Duct / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D001653:Bile Ducts, Intrahepatic / Q000601:surgery; D001918:Brachytherapy; D002780:Cholestasis, Intrahepatic / Q000601:surgery; D003131:Combined Modality Therapy; D004322:Drainage / Q000379:methods; D005260:Female; D006801:Humans; D007495:Iridium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011868:Radioisotopes / Q000627:therapeutic use*
chemical_list: D011868:Radioisotopes; D007495:Iridium