The possible etiological role of retroviruses in human tumors.
A short review of the data on retroviruses and human tumors from the past is given and discussed in comparison to some features of animal oncoviruses. The epidemiological association of a newly isolated retrovirus (HTLV/ATLV) with human adult T-cell lymphomas and the demonstration of onc-genes homologous to those of retroviruses in human cellular DNA has opened new aspects of the possible role of retroviruses in the etiology of human tumors.
D000818:Animals; D002460:Cell Line; D004273:DNA, Neoplasm / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics; D017977:Deltaretrovirus / Q000472:pathogenicity; D006801:Humans; D008223:Lymphoma / Q000382:microbiology; D009369:Neoplasms / Q000235:genetics / Q000382:microbiology*; D009857:Oncogenes; D012190:Retroviridae / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*
D004273:DNA, Neoplasm; D004279:DNA, Viral