Equine immunology 4: vaccines and antisera.
This paper attempts to relate the practicalities of vaccine development to the ideals which should be aimed for in a new vaccine. The type of immune response induced is dependent upon the nature of the antigen in the vaccine and the site and timing of its presentation to the immune system. In this respect the influence of age, maternal immunity and antigenic competition are discussed. The possible side effects associated with vaccination are defined and vaccines which are currently available for horses are reviewed. These vaccines are mostly for the prevention of respiratory disease. Finally, the possible uses for antisera are considered.
D000367:Age Factors; D000818:Animals; D000941:Antigens / Q000276:immunology; D003017:Clostridium tetani / Q000276:immunology; D005260:Female; D004861:Herpesvirus 1, Equid / Q000276:immunology; D006734:Horse Diseases / Q000517:prevention & control; D006736:Horses / Q000276:immunology*; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D008297:Male; D010849:Picornaviridae / Q000276:immunology; D011247:Pregnancy; D012141:Respiratory Tract Infections / Q000517:prevention & control / Q000662:veterinary; D013742:Tetanus / Q000517:prevention & control / Q000662:veterinary; D014611:Vaccination / Q000009:adverse effects / Q000379:methods / Q000662:veterinary*; D014612:Vaccines / Q000009:adverse effects / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000276:immunology; D014777:Virus Diseases / Q000517:prevention & control / Q000662:veterinary
D000941:Antigens; D014612:Vaccines; D014613:Vaccines, Attenuated