Juvenile-type granulosa theca cell tumour producing precocious pseudopuberty. A case report.
The juvenile-type of granulosa theca cell tumour in a young girl is reported. The child presented with pain, vaginal bleeding, distension of the abdomen and enlarged breasts and exhibited pubic and axillary hair, i.e. signs of oestrogenic and androgenic effects and overproduction of luteinizing hormone--an unusual phenomenon. Discussion includes the differences between the juvenile and adult types of this tumour. Salpingo-oophorectomy of the affected side is recommended in such cases. A recurrence many years after surgery has been reported, so long-term follow-up is envisaged in this case.
D002675:Child, Preschool; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology; D011629:Puberty, Precocious / Q000209:etiology*; D013798:Thecoma / Q000150:complications* / Q000473:pathology