Epithelial inclusion cysts following radial keratotomy.
A 26-year old woman underwent radial keratotomy combined with concentric trephination (6.5 and 8 mm) six months prior to development of multiple epithelial inclusion cysts. A biopsy specimen from one enlarging cyst showed an absence of scarring in addition to the retention of epithelium within a radial incision wound. Adjacent keratocytes were abnormal and seemed to be undergoing degenerative changes. To our knowledge, this is the first report of a failure in corneal wound healing associated with microcystic degeneration of the epithelium following radial keratotomy.
D000328:Adult; D003315:Cornea / Q000601:surgery* / Q000648:ultrastructure; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D003318:Corneal Opacity / Q000209:etiology; D003560:Cysts / Q000209:etiology* / Q000473:pathology; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D009216:Myopia / Q000209:etiology; D011183:Postoperative Complications; D014945:Wound Healing