Peripheral facial palsy and coincidental cytomegalovirus infection or reactivation.
Following the fortuitous demonstration of anti-cytomegalovirus (CMV) IgM antibodies in serum samples from 2 patients with acute peripheral facial palsy (APFP), a systematic study was initiated which provided serological evidence of a coincidental CMV multiplication in 72% of 65 consecutive cases with APFP. Transmission electron microscopy has revealed Herpetoviridae-like virus particles in 56% of urine samples studied. A reactivation of latent CMV at the time of palsy onset is considered the most probable explanation of these findings.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000276:immunology / Q000382:microbiology; D005158:Facial Paralysis / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M