[Osteomedullary pathology in 5 cases of systemic mastocytosis. Pseudomyelomatous forms with dysglobulinemia and benign medullary polyclonal plasmacytosis. Hamazaki-Wesenberg Bodies associated with mast cell granuloma].
The authors describe bone marrow lesions in five cases of mastocytosis, with particular emphasis on the characteristic features of the infiltration of the mast cells, and the associated bone and medullary lesions. The five cases show two features not commonly encountered in the literature: the presence of seric dysglobulinemia with medullary polyclonal plasmacytosis in two cases; and the association of mast cells with Hamazaki-Wesenberg bodies in the other three. After recalling the actual mechanisms of bone lesions secondary to mast cell infiltration, the authors propose an explanation for the non-casual association of mastocytosis and Hamazaki-Wesenberg bodies, which has not been previously reported.
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination; D001862:Bone Resorption; D001842:Bone and Bones / Q000473:pathology*; D003937:Diagnosis, Differential; D004406:Dysgammaglobulinemia / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis; D010950:Plasma Cells / Q000473:pathology; D014582:Urticaria Pigmentosa / Q000150:complications / Q000473:pathology*
Pathologie ostéo-médullaire dans cinq cas de mastocytose systématisée. Formes pseudo-myélomateuses avec dysglobulinémie et plasmocytose mĕdullaire polyclonale bénigne. Corps d'Hamazaki-Wesenberg associés aux granulomes mastocytaires.