Collagen composition in the ductal infiltrating carcinoma of human breast.
Ductal infiltrating carcinoma of the breast is characterized by a remarkable amount of collagen fibrils surrounding nests and cords of neoplastic cells. Sequential extractions with pepsin release three classes of intact collagen chains, which have been identified as alpha 1 (I), alpha 2 (I) and alpha 1 (III) types. Alpha 1 (I) is prominent among these classes.
D002293:Adenocarcinoma, Scirrhous / Q000032:analysis*; D000596:Amino Acids / Q000032:analysis; D001943:Breast Neoplasms / Q000032:analysis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000032:analysis*; D003094:Collagen / Q000032:analysis* / Q000096:biosynthesis; D005260:Female; D006801:Humans; D010434:Pepsin A; D011487:Protein Conformation
D000596:Amino Acids; D003094:Collagen; D010434:Pepsin A