title: Psychoactive drugs and stimulus analysis: VI. Evaluation of one-trial modification of exploration as a basis for psychoactive drug classification.
abstract: Findings obtained using a one-trial modification of exploration procedure are reviewed and the suitability of the test as a device for screening and classifying psychoactive drugs is considered. It is concluded that the test has value from a theoretical point of view, in relation to a model of affective disorders based upon the concept of stimulus analysis, but that there are several practical difficulties which limit the test's usefulness as an adjunct to a basic screening programme for new drugs.
mesh_terms: D000818:Animals; D001143:Arousal / Q000187:drug effects*; D002707:Chlordiazepoxide / Q000494:pharmacology; D002712:Chlorides / Q000494:pharmacology; D002746:Chlorpromazine / Q000494:pharmacology; D004193:Discrimination Learning / Q000187:drug effects; D005106:Exploratory Behavior / Q000187:drug effects*; D008094:Lithium / Q000494:pharmacology; D018021:Lithium Chloride; D010634:Phenobarbital / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000145:classification* / Q000494:pharmacology; D051381:Rats; D012931:Social Environment; D014191:Tranylcypromine / Q000494:pharmacology
chemical_list: D002712:Chlorides; D011619:Psychotropic Drugs; D014191:Tranylcypromine; D002707:Chlordiazepoxide; D008094:Lithium; D018021:Lithium Chloride; D002746:Chlorpromazine; D010634:Phenobarbital