Nuclear inclusions in oculopharyngeal dystrophy. An ultrastructural study of six cases.
Nuclear inclusions in striated muscle from patients with oculopharyngeal dystrophy have been detected recently. We carried out ultrastructural examinations of biopsy specimens on 5 patients with oculopharyngeal dystrophy and we also reexamined a former case. In these 6 cases we found filamentous inclusions in a few nuclei. These inclusions seem to be characteristic of this disease as they have never been seen elsewhere.
D000368:Aged; D002467:Cell Nucleus / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000648:ultrastructure; D009136:Muscular Dystrophies / Q000473:pathology*; D009801:Oculomotor Muscles / Q000648:ultrastructure; D010609:Pharyngeal Muscles / Q000648:ultrastructure