19-Oxo-deoxycorticosterone binds to the renal mineralocorticoid receptor and produces sodium retention but not potassium excretion.
D000315:Adrenalectomy; D000450:Aldosterone / Q000378:metabolism; D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D001693:Biological Transport, Active / Q000187:drug effects; D003900:Desoxycorticosterone / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D066298:In Vitro Techniques; D007668:Kidney / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008901:Mineralocorticoids / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D008901:Mineralocorticoids; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid; D003900:Desoxycorticosterone; D000450:Aldosterone; C033576:19-oxo-deoxycorticosterone; D012964:Sodium; D011188:Potassium