Local erythema multiforme-like drug reaction following intravenous mitomycin C and 5-fluorouracil.
A localized skin reaction occurred within 4 weeks following IV administration of mitomycin C and 5-FU. Erythematous papules appeared proximal to the forearm site used for drug administration that histologically resembled an erythema multiforme-like drug reaction. A localized hypersensitivity reaction to mitomycin C is suspected.
D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000209:etiology*; D004892:Erythema Multiforme / Q000139:chemically induced*; D005472:Fluorouracil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000009:adverse effects* / Q000627:therapeutic use
D000903:Antibiotics, Antineoplastic; D008937:Mitomycins; D016685:Mitomycin; D005472:Fluorouracil