title: [Possibility of using the larvae of anuran amphibians as a test model for the quantitative determination of hypophyseal hormones].
abstract: A possibility to use the larvae of ecaudate amphibia as a test model for the quantitative determination of certain hypophyseal hormones has been shown. The physiological reactions of the pigmentary cells in tadpoles of Rana temporaria can be used for a quick and exact testing of the adrenocorticotropic hormone preparations (ACTH): corticotropin and Zn-corticotropin. Evidently the method elaborated for the biological testing of hypophyseal hormones may be used in the production of the endocrinous preparations as a quick assessment of melanocyte-stimulating hormones in integral raw and sublimated hypophyses.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000818:Animals; D001681:Biological Assay / Q000379:methods*; D003366:Cosyntropin / Q000032:analysis; D007814:Larva / Q000187:drug effects; D008547:Melanophores / Q000187:drug effects; D010907:Pituitary Hormones / Q000032:analysis*; D011896:Rana temporaria / Q000502:physiology*
chemical_list: D010907:Pituitary Hormones; D003366:Cosyntropin; C006418:adrenocorticotropin zinc; D000324:Adrenocorticotropic Hormone
vernacular_title: O vozmozhnosti primeneniia lichinok beskhvostykh amfibiĭ v kachestve test-modeli dlia kolichestvennogo opredeleniia nekotorykh gipofizarnykh gormonov.