Synthesis and biological investigations of new tuftsin analogs with elongated peptide chain.
In this paper the synthesis of the following elongated tuftsin analogs: Thr-Lys-Pro-Lys-Thr-Lys-Pro-Lys (I), Thr-Lys-Pro-Lys-Thr-Lys-Pro-Arg (II) and Ala-Lys-Thr-Lys-Pro-Arg-Glu-Gln (III) by the classical method is described. The compound II markedly inhibited the growth of murine sarcoma viruses (MSV).
D000595:Amino Acid Sequence; D000998:Antiviral Agents / Q000138:chemical synthesis; D009053:Sarcoma Viruses, Murine / Q000187:drug effects; D014405:Tuftsin / Q000138:chemical synthesis* / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D014405:Tuftsin