title: Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements.
abstract: Two simian virus 40 transcriptional promoter elements, the 72-base pair (bp) repeat and the 21-bp repeat region, induce chromatin structures of increased DNase I sensitivity when transposed elsewhere in the viral genome. The induction of a sufficiently long stretch of DNase I-sensitive chromatin leads to the appearance of a visible nucleosome-free region.
mesh_terms: D002843:Chromatin / Q000648:ultrastructure*; D004261:DNA Replication; D003851:Deoxyribonucleases; D005786:Gene Expression Regulation; D005809:Genes, Regulator; D009707:Nucleosomes / Q000648:ultrastructure; D009876:Operon; D012091:Repetitive Sequences, Nucleic Acid; D013539:Simian virus 40 / Q000235:genetics*
chemical_list: D002843:Chromatin; D009707:Nucleosomes; D003851:Deoxyribonucleases