Effect of low environmental temperature on adenylate cyclase and phosphodiesterase in rat tissues.
Adult rats were exposed to 5 degrees C for 5 and 24 h and thereafter the adenylate cyclase and phosphodiesterase (EC were studied in heart and liver. The cold exposure caused a significant increase in the myocardial adenylate cyclase with a simultaneous decrease of the phosphodiesterase activity. Long term cold exposure exhibited a decrease in the adenylate cyclase activity and an increase in the phosphodiesterase activity in rat liver.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D003081:Cold Climate; D000242:Cyclic AMP / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D000262:Adenylyl Cyclases