Oligodeoxynucleotides containing 7-deazaadenine: synthesis and recognition by restriction endonucleases.
Deoxydecanucleotides containing a recognition sequence of Bg1 II and Sau 3AI, and their 7-deazaadenine analogs were synthesized by the phosphotriester method. The decanucleotides containing 7-deazaadenine in place of adenine were partially or strongly resistant to the hydrolysis by these restriction endonucleases.
D004262:DNA Restriction Enzymes / Q000378:metabolism; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis*; D009841:Oligonucleotides / Q000138:chemical synthesis*; D013379:Substrate Specificity; D014372:Tubercidin
D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D004262:DNA Restriction Enzymes; D014372:Tubercidin