In vitro differentiation of F-9 teratocarcinoma cells does not induce expression of endogenous retroviral glycoprotein.
Undifferentiated F-9 teratocarcinoma cells derived from 129/J mice are induced in vitro to express several differentiation markers. Neither undifferentiated nor differentiated F-9 cells express endogenous retroviral glycoprotein (gp70), although the latter can be productively infected with exogenous retroviruses. This is discussed in context with previous findings that all antigen-activated lymphocytes of all mice express endogenous retroviral gp70.
D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002454:Cell Differentiation; D002460:Cell Line; D051379:Mice; D009374:Neoplasms, Experimental / Q000378:metabolism; D012190:Retroviridae / Q000378:metabolism; D013724:Teratoma / Q000378:metabolism*; D014212:Tretinoin / Q000494:pharmacology; D014759:Viral Envelope Proteins; D014764:Viral Proteins / Q000032:analysis*
D014759:Viral Envelope Proteins; D014764:Viral Proteins; D014212:Tretinoin; D003994:Bucladesine