title: [Clinical aspects and treatment of "minimal" forms of breast cancer].
abstract: The data on 262 patients with minimal breast cancer (less than 1 cm in diameter) are presented. The long-term results of treatment of this group were good: 5- and 10-year survival rates were 91.2 and 79.5%, respectively. However, minimal breast cancer tended to produce regional (28.5%) and distant (10.3%) metastases. Organ-saving operation, viz. lumpectomy en bloc with axillary-subclavian adipose tissue was frequently (18.5%) followed by local and regional recurrence development. Adjuvant thiotepa therapy caused a 17.8% decrease in the frequency of recurrence and distant metastases development.
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000453:epidemiology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D012426:Russia; D009626:Terminology as Topic; D014505:Urban Population
vernacular_title: Klinika i lechenie "minimal'nykh" form raka molochnoĭ zhelezy.