[Factors controlling stem cell recirculation. 5. Modification of the effects of endogenous glucocorticoids on CFUs migration in T-deficient mice].
It was shown that at a continuously increased level of endogenous glucocorticoids (injection of ACTH) in thymectomized and B mice the degree of inhibition of CFUs migration, that was observed in T-deficient mice without ACTH injection, did not increase. With T-deficiency the stimulatory effect of the hypocorticoid state (adrenalectomy) on the CFUs migration persisted but was less pronounced than in animals with intact thymus.
D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage; D000818:Animals; D002464:Cell Migration Inhibition; D002465:Cell Movement / Q000187:drug effects / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D005260:Female; D005938:Glucocorticoids / Q000502:physiology*; D006412:Hematopoietic Stem Cells / Q000276:immunology* / Q000528:radiation effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology* / Q000528:radiation effects; D013934:Thymectomy; D013997:Time Factors
D005938:Glucocorticoids; D000324:Adrenocorticotropic Hormone
Faktory, kontroliruiushchie retsirkuliatsiiu stvolovykh kletok. Soobshchenie 5. Modifikatsiia éffektov éndogennykh gliukokortikoidov na migratsiiu KOEs u T-defitsitnykh mysheĭ.