[Effect of morphine on polyphosphoinositides of erythrocytes of spontaneously hypertensive rats].
Morphine (1 X 10(-5) mol/l) did not affect the incorporation of 32P into the phosphoinositides of erythrocytes from spontaneously hypertensive and normotensive Wistar Kyoto rats, whereas the content of triphosphoinositides was decreased. In spontaneously hypertensive rats the content of total phospholipids was decreased in the same ratio. Thus, the effect of morphine (at this concentration) on the membrane phospholipids of spontaneously hypertensive rats seems to be unspecific.
D000818:Animals; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006973:Hypertension / Q000097:blood*; D008297:Male; D009020:Morphine / Q000494:pharmacology*; D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols / Q000097:blood* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D018129:Phosphatidylinositol Phosphates; D010716:Phosphatidylinositols; D009020:Morphine
Wirkung von Morphin auf die Polyphosphoinositide der Erythrozyten spontan hypertoner Ratten.