Rapid selective brain-cooling using head immersion and naso-oral perfusion in dogs.
Utilizing a technique of selective surface head cooling and naso-oral perfusion, rapid profound cooling of the brain to 14-19 degrees C with maintenance of body temperature has been achieved in 24 dogs. Post perfusion, neurological examination of the animals were within normal limits, and neuropathological review of brain specimens demonstrated absence of tissue abnormality.
D000818:Animals; D001831:Body Temperature; D001921:Brain / Q000502:physiology*; D004285:Dogs; D007036:Hypothermia, Induced / Q000379:methods*; D010477:Perfusion