Case report of symptomatic porphyria cutanea tarda associated with histiocytic lymphoma.
A fifth case is reported of symptomatic porphyria cutanea tarda (PCT) associated with lymphoma (of the histiocytic type) in a 45-year-old female. The PCT was documented in detail histologically and biochemically. The lymphoma was complicated by two paraneoplastic phenomena: inappropriate antidiuretic hormone secretion and peripheral neuropathy. It is possible that the PCT might also be a paraneoplastic phenomenon of the lymphoma. Search for an occult lymphoma may be of diagnostic and therapeutic value in patients presenting with PCT.
D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000209:etiology; D011164:Porphyrias / Q000209:etiology*; D012871:Skin Diseases / Q000209:etiology*