[Metabolism of benzo(a)pyrene in rat pleural mesothelial cells in culture].
Cultures of Rat pleural mesothelial cells obtained after isolation of parietal cells metabolized benzo(a)pyrene to organosoluble and hydrosoluble derivatives. This property is well maintained since it was observed with cells at 6th passage as well as after 39 passages.
D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000378:metabolism*; D002273:Carcinogens / Q000378:metabolism*; D002478:Cells, Cultured; D004848:Epithelium / Q000502:physiology; D005347:Fibroblasts / Q000502:physiology; D005965:Glucuronates / Q000302:isolation & purification; D005978:Glutathione / Q000302:isolation & purification; D010994:Pleura / Q000502:physiology; D051381:Rats; D012995:Solubility; D013464:Sulfuric Acids / Q000302:isolation & purification
D001580:Benzopyrenes; D002273:Carcinogens; D005965:Glucuronates; D013464:Sulfuric Acids; D001564:Benzo(a)pyrene; D005978:Glutathione
Métabolisme du benzo(a)pyrène par des cellules mésothéliales pleurales de rat en culture.