[Coexistence of myeloma and chronic myeloid leukemia].
The case of an eighty-one-year-old woman who had myeloma followed 18 months later by chronic myeloid leukemia with Philadelphia chromosome unrelated to therapeutic interferences is reported. This case is compared to other reports of lymphoid hemopathies associated with myeloid hemopathies found in the medical literature. The different etiopathogenic hypotheses are discussed, particularly in the light of recent studies of chromosomes. Such caryotypic studies in malignant hemopathies may improve our knowledge of the connexions between apparently dissimilar diseases and prove helpful for the understanding of cell differentiation from pathological data.
D000368:Aged; D002904:Chromosomes, Human, 21-22 and Y; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D009101:Multiple Myeloma / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*
Coexistence d'un myélome et d'une leucémie myéloïde chronique.