title: Granulocyte proteases in human maxillary sinus secretions.
abstract: Retained maxillary sinus secretions from 10 consecutive patients suffering from maxillary sinusitis were studied with regard to proteolytic activity and its possible sources. All secretions were proteolytically active. In 3 purulent secretions the proteolytic activity was of the same magnitude as that of a standard with an excess of pancreatic trypsin. The enzymes responsible for the proteolytical activity were found to be mainly of granulocyte origin, neutrophil elastase, unspecific collagenase and chymotrypsin-like cationic protein (CCP).
mesh_terms: D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000032:analysis; D005260:Female; D006098:Granulocytes / Q000201:enzymology* / Q000378:metabolism; D006801:Humans; D007122:Immunoelectrophoresis; D007781:Lactoferrin / Q000032:analysis; D008297:Male; D008443:Maxillary Sinus / Q000378:metabolism*; D003012:Microbial Collagenase / Q000096:biosynthesis; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000096:biosynthesis; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D012852:Sinusitis / Q000201:enzymology*; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D001798:Blood Proteins; D000515:alpha 1-Antitrypsin; C015078:chymotrypsin-like cationic protein, human; D010447:Peptide Hydrolases; D007781:Lactoferrin; D010196:Pancreatic Elastase; D003012:Microbial Collagenase