Delayed-type hypersensitivity in mice after infection with avirulent Semliki Forest virus. Brief report.
After subcutaneous infection of mice with Semliki Forest virus, a delayed-type hypersensitivity (DH) could be demonstrated by footpad swelling. Pretreatment with cyclophosphamide resulted in enhanced DH if neutralizing antibodies were undetectable in serum.
D000818:Animals; D003520:Cyclophosphamide / Q000494:pharmacology; D006968:Hypersensitivity, Delayed / Q000209:etiology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D012672:Semliki forest virus; D014036:Togaviridae Infections / Q000276:immunology*
D003520:Cyclophosphamide