title: [Metabolism of benzo(a)pyrene in rat pleural mesothelial cells in culture].
abstract: Cultures of Rat pleural mesothelial cells obtained after isolation of parietal cells metabolized benzo(a)pyrene to organosoluble and hydrosoluble derivatives. This property is well maintained since it was observed with cells at 6th passage as well as after 39 passages.
mesh_terms: D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000378:metabolism*; D002273:Carcinogens / Q000378:metabolism*; D002478:Cells, Cultured; D004848:Epithelium / Q000502:physiology; D005347:Fibroblasts / Q000502:physiology; D005965:Glucuronates / Q000302:isolation & purification; D005978:Glutathione / Q000302:isolation & purification; D010994:Pleura / Q000502:physiology; D051381:Rats; D012995:Solubility; D013464:Sulfuric Acids / Q000302:isolation & purification
chemical_list: D001580:Benzopyrenes; D002273:Carcinogens; D005965:Glucuronates; D013464:Sulfuric Acids; D001564:Benzo(a)pyrene; D005978:Glutathione
vernacular_title: Métabolisme du benzo(a)pyrène par des cellules mésothéliales pleurales de rat en culture.