title: Molecular epidemiology of human rotaviruses. Analysis of outbreaks of acute gastroenteritis in Glasgow and the west of Scotland 1981/82 and 1982/83.
abstract: The molecular epidemiology of rotavirus infections in Glasgow and the west of Scotland during 1981/82 and 1982/83 was investigated by electron microscopy, ELISA testing and RNA migration pattern analysis. In 1981/82, rotaviruses of both the 'long' and the 'short' electropherotype (in different variants) co-circulated from the onset throughout the winter peak of the outbreak. Approximately 80% of the children were infected during the first year of life. No differences in incidence were found between sexes. In 1982/83 the isolated rotaviruses were almost exclusively of the 'long' electropherotype (in different variants) and 36% of the children were infected beyond the first year of life. Rotaviruses of the 'long' electropherotype serologically were of subgroup II and serotype 1 and those of the 'short' electropherotype of subgroup I and serotype 2.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000956:Antigens, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000453:epidemiology*; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000382:microbiology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008854:Microscopy, Electron; D012367:RNA, Viral / Q000032:analysis; D012401:Rotavirus / Q000032:analysis* / Q000145:classification; D012400:Rotavirus Infections / Q000453:epidemiology / Q000382:microbiology*; D012606:Scotland; D012703:Serotyping
chemical_list: D000956:Antigens, Viral; D012367:RNA, Viral