DNA sequence of the Herpes simplex virus type 2 glycoprotein D gene.
We describe a 1635-bp Herpes simplex virus type 2 (HSV-2) DNA sequence containing the entire coding region of glycoprotein D (gD-2). The amino acid sequence of gD-2, deduced from the nucleotide sequence, was compared to that of the analogous Herpes simplex virus type 1 (HSV-1) glycoprotein (gD-1). The two glycoproteins are 85% homologous and contain highly conserved regions of as much as 49 amino acids in length. Comparison of DNA sequences upstream from gD-1 and gD-2 coding regions identified possible conserved regulatory sequences.
D000595:Amino Acid Sequence; D001483:Base Sequence; D005814:Genes, Viral; D006023:Glycoproteins / Q000235:genetics*; D018139:Simplexvirus / Q000235:genetics*; D013045:Species Specificity; D014759:Viral Envelope Proteins; D014764:Viral Proteins / Q000235:genetics*
D006023:Glycoproteins; D014759:Viral Envelope Proteins; D014764:Viral Proteins; C040570:glycoprotein D-herpes simplex virus type 2