title: Gene coding assignments for growth restriction, neutralization and subgroup specificities of the W and DS-1 strains of human rotavirus.
abstract: Gene coding assignments for growth restriction, neutralization and subgroup specificities were determined for two human rotavirus strains, DS-1 and W, which represent two distinct serotypes. The 4th gene segment of both viruses was associated with restriction of growth in cell culture. The 9th gene segment of W virus and 8th segment of DS-1 were associated with serotype specificity, while the 6th gene segment of W virus was associated with subgroup specificity.
mesh_terms: D005814:Genes, Viral; D005815:Genetic Code; D005838:Genotype; D009500:Neutralization Tests; D012401:Rotavirus / Q000235:genetics* / Q000254:growth & development; D012703:Serotyping