title: On the occurrence of gastrin releasing peptide (GRP)-like immunoreactive nerve fibers in the celiac ganglion of rats.
abstract: Gastrin releasing peptide (GRP)-like immunoreactive fibers occurred among and around ganglion cells in the forms of punctate structures or varicose processes in the celiac ganglion of rats. The density of the fibers varied from region to region in single sections. The immunoreactive nerve fibers were characterized by abundant large granular vesicles mixed with small clear vesicles, and they formed axo-dendritic synapses with principal ganglion cells. The immunoreactive material was localized on the granular core and also in the axoplasm. No immunoreactive ganglion cells were found in any portion of the ganglion. The present findings suggest that the GRP fibers are of extraganglionic origin and that GRP is involved in the ganglionic transmission of the prevertebral ganglion.
mesh_terms: D000818:Animals; D005728:Ganglia, Sympathetic / Q000378:metabolism*; D019886:Gastrin-Releasing Peptide; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000378:metabolism; D009474:Neurons / Q000378:metabolism; D010455:Peptides / Q000378:metabolism*; D051381:Rats; D009435:Synaptic Transmission
chemical_list: D005768:Gastrointestinal Hormones; D010455:Peptides; D019886:Gastrin-Releasing Peptide