Influence of Sendai virus on carcinogenesis in strain A mice.
An alkylating derivative of a hydrocarbon, 10-chloromethyl-9-chloroanthracene, gave rise to reduced numbers of chemically induced pulmonary adenomas in strain A mice enzootically infected with Sendai virus, while in the case of 7,12-dimethylbenz(a)anthracene, the opposite relationship was observed. Therefore, the presence or absence of viral infection was demonstrated to have a strong influence on carcinogenic susceptibility.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D005260:Female; D008175:Lung Neoplasms / Q000139:chemically induced; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D010222:Parainfluenza Virus 1, Human / Q000472:pathogenicity; D018184:Paramyxoviridae Infections / Q000150:complications*
D015127:9,10-Dimethyl-1,2-benzanthracene