Retinal cAMP levels in the mouse: lack of effect of the major histocompatibility locus.
Studies of retinal cAMP have previously neglected the effects of the major histocompatibility locus, which is a confounding variable for cAMP levels in a variety of tissues. We have determined posterior globe cAMP in dark- and light-adapted mice of two inbred, and their respective H-2 congenic, strains of mice. No significant difference in cAMP levels was found among the inbred strains of mice while marked effects of dark adaptation were confirmed.
D000818:Animals; D000242:Cyclic AMP / Q000235:genetics* / Q000378:metabolism; D003623:Dark Adaptation; D006183:H-2 Antigens / Q000235:genetics*; D051379:Mice; D008815:Mice, Inbred Strains; D012160:Retina / Q000378:metabolism*
D006183:H-2 Antigens; D000242:Cyclic AMP