title: Structure of a human gastrin gene.
abstract: A gastrin gene was isolated from a genomic library of human DNA. The human gastrin gene is about 4100 base pairs long and contains two intervening sequences. Thus, a 3500-base-pair intervening sequence is located 5 base pairs proximal to the ATG initiator codon, while a 129-base-pair intervening sequence separates the region coding for the principal hormonal form of gastrin, the heptadecapeptide, from the region coding for the major amino-terminal portion of the gastrin precursor. The 5' flanking region of the gene contains the conserved sequences, T-A-T-A-A and G-A-C-T-C-A-T-A-T, in positions similar to those of other eukaryotic genes.
mesh_terms: D000595:Amino Acid Sequence; D001482:Base Composition; D001483:Base Sequence; D003001:Cloning, Molecular; D003062:Codon; D004247:DNA / Q000032:analysis; D004262:DNA Restriction Enzymes; D005755:Gastrins / Q000235:genetics*; D005796:Genes; D006801:Humans; D009693:Nucleic Acid Hybridization
chemical_list: D003062:Codon; D005755:Gastrins; D004247:DNA; D004262:DNA Restriction Enzymes