title: Protein-free models for the proton-coupled reduction of haemoproteins.
abstract: Reduction of the bis-pilocarpate-haemin complex at pH greater than or equal to 10 involves the simultaneous uptake of an electron by the Fe(III) ion and a proton by the pendant alkoxide group of an axial ligand. This provides a protein-free model for reactions such as the proton-coupled reduction of cytochromes which involve cooperative Coulombic interaction between two non-bonded sites.
mesh_terms: D005290:Ferric Compounds; D006420:Hemeproteins; D006427:Hemin; D008956:Models, Chemical; D010084:Oxidation-Reduction; D010862:Pilocarpine; D011522:Protons
chemical_list: D005290:Ferric Compounds; D006420:Hemeproteins; D011522:Protons; D010862:Pilocarpine; D006427:Hemin