title: [Antimitotic chemotherapy of supratentorial cerebral glioma in adults. Apropos of 56 cases].
abstract: Fifty-six patients with supratentorial gliomas were given chemotherapy (VM 26 and CCNU). Results were analyzed and compared to recent data from the medical literature. After the first great expectations the place of chemotherapy in the management of primary gliomas has now been more accurately delineated: it is an adjunctive therapy, complementary to surgery and radiotherapy. The contribution of chemotherapy, although slight, is unquestionable: in 2/3 of cases a significant improvement of the length of survival can be expected.
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D004359:Drug Therapy, Combination; D005260:Female; D005910:Glioma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008130:Lomustine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009607:Nitrosourea Compounds / Q000008:administration & dosage*; D011034:Podophyllotoxin / Q000031:analogs & derivatives*; D013713:Teniposide / Q000008:administration & dosage*
chemical_list: D009607:Nitrosourea Compounds; D008130:Lomustine; D013713:Teniposide; D011034:Podophyllotoxin
vernacular_title: Chimiothérapie anti-mitotique des gliomes cérébraux sus-tentoriels de l'adulte. A propos de cinquante-six observations.