title: Oral histoplasmosis: diagnostic complication and treatment.
abstract: Intraoral histoplasmosis is difficult to diagnose, both because the clinician fails to be aware of it and because the lesion has clinical similarities to other disease entities, creating a misleading clinical impression. Effective communication between clinician and pathologist is essential, if one is to arrive at an accurate diagnosis and provide the best treatment. A new antimycotic agent, ketoconazole, is now available for oral administration. Studies indicate that it has major therapeutic advantages and significantly lower toxicity than comparable antimycotic agents.
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003937:Diagnosis, Differential; D006660:Histoplasmosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D007654:Ketoconazole; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy / Q000473:pathology*; D009062:Mouth Neoplasms / Q000473:pathology; D010879:Piperazines / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D007093:Imidazoles; D010879:Piperazines; D007654:Ketoconazole