Ferritinemia in ovarian malignant tumours.
Seriated ferritin assays were carried out on 95 patients affected by primitive ovarian epithelial tumour over a period of three years (1979/82), by radioimmunometric assay for human spleen ferritin. Ferritin was elevated in endometrioid tumours and in the presence of active progressing disease and chemotherapy did not influence these values. The ferritin/sideremia ratio was high in the case with pathological levels. Studying the glicosilation of this protein a significant amount of ferritin was not bound to concavallin A, suggesting direct release of this protein by tumour cells.
D000230:Adenocarcinoma / Q000097:blood; D002288:Adenocarcinoma, Mucinous / Q000097:blood; D002277:Carcinoma / Q000097:blood; D004715:Endometriosis / Q000097:blood; D005260:Female; D005293:Ferritins / Q000097:blood*; D005500:Follow-Up Studies; D006801:Humans; D007501:Iron / Q000097:blood; D008649:Mesonephroma / Q000097:blood; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D011863:Radioimmunoassay
D005293:Ferritins; D007501:Iron