title: Pigbel in Papua New Guinea: an ancient disease rediscovered.
abstract: A hypothesis suggested in this paper is that pigbel, or enteritis necroticans was a common disease in mediaeval Europe when human habitats, food hygiene, protein deficiency and periodic meat feasting formed the basics of village life as they do in many Third World cultures today. Based on the Papua New Guinea experience with pigbel, it is suggested that health authorities should look closely at the epidemiology of the acute surgical abdomen in such communities. Enteritis necroticans may be the important predisposing lesion to mid-gut volvulus, jejunal and ileal ileus and other forms of small bowel strangulation in communities where protein deprivation, poor food hygiene, epochal meat feasting and staple diets containing trypsin inhibitors co-exist. Such human habitats occur in Central South America, Western Pacific, Asian and South-East Asian cultures. Isolated outbreaks of necrotising enteritis have been reported from Uganda, Malaysia and Indonesia but as yet no systematic epidemiological studies of the prevalence of small bowel strangulations have been described in the surgical literature of Third World countries. Now that enteritis necroticans is preventable by vaccination such studies should be undertaken.
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology*; D002648:Child; D003015:Clostridium Infections / Q000150:complications / Q000209:etiology* / Q000517:prevention & control; D003016:Clostridium perfringens; D003906:Developing Countries; D004751:Enteritis / Q000150:complications / Q000209:etiology*; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D010219:Papua New Guinea; D014612:Vaccines
chemical_list: D014612:Vaccines