Radiation treatment of carcinoma of the oropharynx. Report on 201 patients.
The prognosis for 201 patients with carcinoma of the oropharynx, treated mainly by irradiation, was analyzed. The crude 5, 10, 15 and 20 year survival rates were 50.3 per cent, 36 per cent, 26 per cent, and 17 per cent respectively, and the corresponding cure rates 44, 35, 26 and 17 per cent respectively. Patients under 50 years of age had a better 5 year survival than those over 60 years. The poorly differentiated and the anaplastic carcinomas had a better prognosis than the well differentiated lesions. Early stages had a much better prognosis than advanced lesions. Split course and continuous course irradiation gave similar results. The optimum dose range was 60 to 70 Gy. Early disappearance of the primary tumor during radiation therapy was prognostically favourable.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000532:radiotherapy*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D011379:Prognosis; D011867:Radioisotope Teletherapy; D011882:Radiotherapy, High-Energy
D003037:Cobalt Radioisotopes