Ultrastructural study of corpora amylacea in human thyroid gland.
Large cytoplasmic inclusions, corpora amylacea, were found in the follicle epithelial cells of a thyroid with medullary carcinoma. They were varied in size from 1.5 to 10 microns in dimension and the shapes were from fusiform to irregularly formed. Fine fibrils 8 to 23 nm in diameter were randomly arranged within the inclusions. The findings from our work and experience of others suggest that the inclusion bodies may be nonspecific or that an accumulation of abnormal cellular inclusions could be caused by various illness.
D000328:Adult; D000682:Amyloid / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis / Q000648:ultrastructure*; D006801:Humans; D002479:Inclusion Bodies / Q000032:analysis / Q000648:ultrastructure*; D008854:Microscopy, Electron; D013964:Thyroid Neoplasms / Q000032:analysis / Q000648:ultrastructure*
D000682:Amyloid