The genetics of viral infection pathology.
The genetic diversity of viruses and the genetic constitution (polygenic configuration) of susceptible organisms participate together in the determination of a virus disease and of its clinical forms. Genes of sensitivity to viral infection, genes of nonspecific defense (encoding for interferons, complement factors), immune response regulating genes and immunoglobulin genes would form the background of an intrinsic polygenic group involved in viral infection pathology.
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004251:DNA Transposable Elements; D004198:Disease Susceptibility; D005796:Genes; D005802:Genes, MHC Class II; D005814:Genes, Viral; D006680:HLA Antigens; D006801:Humans; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000235:genetics; D009154:Mutation; D009857:Oncogenes; D011995:Recombination, Genetic; D014777:Virus Diseases / Q000235:genetics* / Q000276:immunology
D004251:DNA Transposable Elements; D006680:HLA Antigens; D007136:Immunoglobulins