title: [Prevention of headache following lumbar puncture. A controlled double blind trial of the effectiveness of intravenous tiapride].
abstract: To evaluate the effectiveness of intravenous tiapride in preventing cephalalgia following rachiocentesis, two groups of patients were studied in a double blind trial. In group I (tiapride), two 100 mg vials of tiapride given in a slow intravenous injection were effective in 86.7% of patients. In group II (placebo), only 46.6% of patients did not experience cephalalgia. These results were shown to be statistically significant by the Hypothesis Zo test (Zo = 2,33 for p less than 1%).
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001549:Benzamides / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006261:Headache / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009192:Myelography / Q000009:adverse effects*; D013129:Spinal Puncture / Q000009:adverse effects*; D013976:Tiapamil Hydrochloride / Q000627:therapeutic use*
chemical_list: D001549:Benzamides; D013976:Tiapamil Hydrochloride
vernacular_title: Prévention des céphalées survenant après rachicentèse. Essai controlé en double aveugle de l'efficacité du tiapride intraveineux.