title: [Mathematical model of the interaction of cations and anions in a channel].
abstract: A mathematical model of the ionic channel permeable both to anions and cations is considered. The model takes into account the electrostatic interaction between oppositely charged ions and does not suppose single-file movement. An equation for zero-current potential is derived, which leads to the Goldman equation in the limit of low ion concentrations. The model is used to describe concentration relationships of zero-current potentials on a lipid bilayer with amphotericin B channels which cannot be described on the basis of the independence principle.
mesh_terms: D000838:Anions; D001692:Biological Transport; D002412:Cations; D007473:Ion Channels / Q000378:metabolism*; D008433:Mathematics; D008954:Models, Biological
chemical_list: D000838:Anions; D002412:Cations; D007473:Ion Channels
vernacular_title: Matematicheskaia model' vzaimodeĭstviia kationov i anionov v kanale.