title: [Role of polyfunctional glucose-6-phosphatase in the liver carbohydrate metabolism of the developing chick embryo].
abstract: Glucose-6-phosphatase was shown to be polyfunctional in the liver of the developing chick embryo. Changes in the activity of glucose-6-phosphate phosphohydrolase did not correlate with the rate of gluconeogenesis. The activity of this enzyme increased from the 16th to the 20th day of embryogenesis. The activities of pyrophosphate-glucose phosphotransferase, carbamyl-phosphate-glucose phosphotransferase did not change during embryogenesis. The ratio of the activities of phosphohydrolase and phosphotransferases was characterized by the predominance of the phosphohydrolase activity. The values of latency of phosphohydrolase and phosphotransferases did not correlate with the rate of gluconeogenesis. Glucose-6-phosphate phosphohydrolase was found not only in the microsomal, but in the nuclear fraction as well. KM(G6P) of the enzyme of the nuclear fraction differed from KM of the microsomal enzyme.
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D002642:Chick Embryo / Q000201:enzymology*; D005943:Gluconeogenesis; D005952:Glucose-6-Phosphatase / Q000502:physiology*; D006019:Glycolysis; D008099:Liver / Q000196:embryology / Q000201:enzymology*; D013997:Time Factors
chemical_list: D005952:Glucose-6-Phosphatase
vernacular_title: Rol' polifunktsional'noĭ gliukozo-6-fosfatazy v uglevodnom obmene pecheni razvivaiushchegosia émbriona kuritsy.