title: Potentiation of a conditioned taste aversion in preweanling and adult rats.
abstract: Preweanling (18 days old) and adult rats were made ill with LiCl either 2 min or 1 hr after tasting controlled amounts of either one of two single flavors (saccharin or NaCl) or a compound mixture of the two. Conditioning was assessed with a single test 4 days later relative to explicitly unpaired control conditions. Generally, potentiation of the aversions to either flavor occurred for animals conditioned to the compound. The potentiation effect was decreased or eliminated by nonreinforced exposure to the alternative flavor of the compound. These effects tended to be stronger for the younger rats. Specifically, adult animals did not express potentiation of the saccharin aversion whereas preweanlings expressed potentiated salt aversions. Nonreinforced exposure to the alternative element eliminated the potentiation effect. Conditions conducive to potentiation are discussed in light of investigators who have not observed this effect in similar studies with compound stimuli.
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D001362:Avoidance Learning / Q000187:drug effects; D002712:Chlorides / Q000506:poisoning; D003214:Conditioning, Classical / Q000187:drug effects; D005108:Extinction, Psychological / Q000187:drug effects; D008094:Lithium / Q000506:poisoning; D018021:Lithium Chloride; D051381:Rats; D011919:Rats, Inbred Strains; D012439:Saccharin; D012462:Saline Solution, Hypertonic; D013649:Taste / Q000187:drug effects
chemical_list: D002712:Chlorides; D012462:Saline Solution, Hypertonic; D008094:Lithium; D012439:Saccharin; D018021:Lithium Chloride