GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone.
Cytochrome oxidase activity and mitochondrial GDP binding were decreased in brown adipose tissue of mice treated chronically with corticosterone. These changes occurred both in corticosterone-treated mice fed ad libitum and in treated mice pair-fed to control animals. Although the dietary stimulation of brown-adipose-tissue thermogenesis was suppressed by corticosterone, the acute response to cold was not affected.
D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D000818:Animals; D003080:Cold Temperature; D003345:Corticosterone / Q000494:pharmacology*; D003576:Electron Transport Complex IV / Q000378:metabolism; D005502:Food; D006150:Guanine Nucleotides / Q000378:metabolism*; D006153:Guanosine Diphosphate / Q000378:metabolism*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism
D006150:Guanine Nucleotides; D006153:Guanosine Diphosphate; D003576:Electron Transport Complex IV; D003345:Corticosterone