[Properties of the channels induced by Lityphantes paykullianus venom].
It was found that common venom of Lityphantes paykullianus is capable of forming conductivity channels on bilayer phospholipid membrane. The values of channel conductivity are remarkably distinguished in the solutions of different alkaline metals. The selectivity of channels is mainly cationic at pH 7.5 with weak discrimination of ions few tell one from the other by size. These results indicate that there is an active component in the common venom accountable for channels formation.
D000818:Animals; D001180:Arthropod Venoms / Q000494:pharmacology*; D001921:Brain; D002417:Cattle; D002712:Chlorides / Q000378:metabolism; D007473:Ion Channels / Q000378:metabolism / Q000502:physiology*; D008051:Lipid Bilayers; D008564:Membrane Potentials / Q000187:drug effects; D010743:Phospholipids; D013111:Spider Venoms / Q000494:pharmacology*
D001180:Arthropod Venoms; D002712:Chlorides; D007473:Ion Channels; D008051:Lipid Bilayers; D010743:Phospholipids; D013111:Spider Venoms
Svoĭstva kanalov, obrazuemykh iadom pauka Lityphantes paykullianus.