title: Paget's disease of the vulva: diagnostic and therapeutic problems.
abstract: Two cases of Paget's disease of the vulva are presented and the complex problem of diagnosis of this neoplasia is evaluated: all the diagnosis tests used in vulvar disease (vulvar citology, toluidine blue test) are insufficient in the presence of on eventual underlying carcinoma. In view of these considerations, the therapeutic approach is total vulvectomy.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D010145:Paget Disease, Extramammary / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D014846:Vulvar Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery