Production of immunoreactive pancreatic growth hormone-releasing factor in small cell carcinoma of the lung.
A specific and sensitive radioimmunoassay for human pancreatic growth hormone-releasing factor (hpGRF) was developed. Using this radioimmunoassay, it was found that immunoreactive hpGRF (which is present in hypothalamic tissues) of at least two different molecular sizes is often produced by small cell carcinoma of the lung.
D001943:Breast Neoplasms / Q000378:metabolism; D018288:Carcinoma, Small Cell / Q000378:metabolism*; D002850:Chromatography, Gel; D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism* / Q000031:analogs & derivatives; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism*; D008168:Lung / Q000378:metabolism; D008175:Lung Neoplasms / Q000378:metabolism*; D008970:Molecular Weight; D010446:Peptide Fragments / Q000378:metabolism*; D011863:Radioimmunoassay; D013274:Stomach Neoplasms / Q000378:metabolism
D010446:Peptide Fragments; C036893:somatotropin releasing factor 40; C040787:somatotropin releasing hormone (1-37); C040786:somatotropin releasing hormone (1-44)amide; D013007:Growth Hormone-Releasing Hormone