title: [Role of interstitial radiation in the treatment of glioma].
abstract: Therapy of glioma is a function of numerous factors: their histology, localization and size, but also the age and functional state of the patient. Interstitial radiation by temporary implantation of Iridium 192 needles is recommended only under certain precise conditions: for tumors surgically inaccessible because of their deep localization or their site in a highly functional region, and for those with diameters of less than 35 mm. This restricts the number of cases that can be treated (45 in the present series). Numerous adverse reactions developed, either in the short (initial deficit and edematous reactions), medium (epilepsy) or long term (radionecrosis). However, many were regressive and the treatment is satisfactorily tolerated in view of the localization of these tumors in highly functional regions.
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000532:radiotherapy; D001918:Brachytherapy / Q000009:adverse effects; D004827:Epilepsy / Q000209:etiology; D005500:Follow-Up Studies; D005909:Glioblastoma / Q000532:radiotherapy; D005910:Glioma / Q000532:radiotherapy*; D006801:Humans; D007495:Iridium / Q000627:therapeutic use; D008875:Middle Aged; D011868:Radioisotopes / Q000627:therapeutic use
chemical_list: D011868:Radioisotopes; D007495:Iridium
vernacular_title: La place de l'irradiation interstitielle dans le traitement des gliomes.