title: [Human oncogenic viruses].
abstract: Human oncogenic viruses are ubiquitous pathogens which only in frequently exhibit their malignant potential under natural conditions. They are either ARN viruses, also called retroviruses, of which little is known in man, or DNA viruses belonging to various families (papovavirus, adenovirus, herpes virus, hepatitis B virus), some of which are very specifically associated with certain human carcinomas. In vitro, these viruses induce "cell transformation" producing malignant cells with unregulated growth. In vivo, in man as well as in animals, viral oncogenesis requires multiple cofactors so that the transformed cell can escape control mechanisms.
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic; D004279:DNA, Viral; D006801:Humans; D009858:Oncogenic Viruses / Q000145:classification* / Q000235:genetics / Q000502:physiology; D012367:RNA, Viral
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral
vernacular_title: Les virus oncogènes humains.