Significance of detrusor compliance in patients with localized partial lesions of the spinal cord and cauda equina.
Detrusor compliance was measured by cystometry irrespective of any symptoms of lower urinary trace dysfunction in 70 patients with localized, partial, surgically treatable lesions of the spinal cord and cauda equina. Compliance was found to be normal in all patients with upper motor neuron lesions; reduced compliance was encountered only in those with lower motor neuron lesions. Reduced compliance was closely associated with lesions of the conus medullaris and with detrusor hyperreflexia, and it is therefore likely that the mechanism of compliance involves a significant neural component. Incontinence, particularly nocturnal incontinence, was encountered more frequently among those with reduced compliance than in those with normal compliance, whereas retention of urine was comparatively rare with reduced compliance.
D000328:Adult; D000368:Aged; D002420:Cauda Equina; D003187:Compliance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009468:Neuromuscular Diseases / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology*; D013118:Spinal Cord Diseases / Q000503:physiopathology*; D001743:Urinary Bladder / Q000503:physiopathology*; D001750:Urinary Bladder, Neurogenic / Q000503:physiopathology; D014555:Urination Disorders / Q000503:physiopathology