title: Analysis of small and large plaque variants of equine herpesvirus type 3 by restriction endonucleases. Brief report.
abstract: Six of 6 equine herpesvirus type 3 (EHV3) isolates, 5 of which were epidemiologically unrelated, produced a mixture of small and large plaque variants in equine foetal kidney cells under methylcellulose. In 4 of 4 instances the cleavage site(s) generating the Bam HI A fragment of large plaque variants was distinct from the site(s) for the same fragment of small plaque variants.
mesh_terms: D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis*; D015245:Deoxyribonuclease BamHI; D015247:Deoxyribonuclease HindIII; D014644:Genetic Variation; D006564:Herpesviridae / Q000254:growth & development*; D004858:Herpesvirus 3, Equid / Q000032:analysis / Q000235:genetics / Q000254:growth & development*; D010948:Viral Plaque Assay
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI; D015247:Deoxyribonuclease HindIII