title: Neophobia and conditioned taste aversion deficits in the rat produced by undercutting temporal cortex.
abstract: Adult male hooded rats with parasagittal knife-cuts between the amygdala and temporal cortex (n = 8), with electrolytic basolateral amygdala lesions (n = 8), and sham-operated controls (n = 8), were tested for neophobia and LiCl-induced aversion to a 0.1% saccharin solution in a one-bottle forced choice paradigm. Both types of lesion produced equal deficits in neophobia and conditioned aversion. It was concluded that severing the connections between the amygdala and the temporal cortex produces the same deficits as basolateral amygdala damage. Possible anatomical substrates for these effects are discussed.
mesh_terms: D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D002712:Chlorides / Q000506:poisoning; D003214:Conditioning, Classical / Q000502:physiology*; D004326:Drinking / Q000187:drug effects; D008094:Lithium / Q000506:poisoning; D018021:Lithium Chloride; D009115:Muridae; D009434:Neural Pathways / Q000502:physiology; D013649:Taste / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*
chemical_list: D002712:Chlorides; D008094:Lithium; D018021:Lithium Chloride