Ontogenesis of beta-adrenergic binding sites in kitten visual cortex and the effects of visual deprivation.
We have determined maximum binding capacities for beta-adrenergic binding sites in developing cat visual cortex. These increase quickly from birth to 4 weeks, after which time a slower increase reaches maximal levels at 12 weeks. Dark-rearing and monocular eyelid suture have no influence on this developmental profile.
D000818:Animals; D002415:Cats; D002454:Cell Differentiation; D003623:Dark Adaptation; D004082:Dihydroalprenolol / Q000378:metabolism; D004292:Dominance, Cerebral / Q000502:physiology; D009473:Neuronal Plasticity; D009638:Norepinephrine / Q000378:metabolism; D011941:Receptors, Adrenergic / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*; D012683:Sensory Deprivation / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology*; D014795:Visual Pathways / Q000166:cytology; D014796:Visual Perception / Q000502:physiology*
D011941:Receptors, Adrenergic; D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol; D009638:Norepinephrine