title: [The effect of zeolite on experimentally induced acidosis in sheep].
abstract: The effect of zeolite (clinoptilolite) on experimentally induced metabolic acidosis was studied in sheep under experimental conditions. Sucrose was administered at the doses of 10 and 15 g per kg l. w. either alone or, in other groups, together with 0.45 g zeolite per kg l. w. The content of volatile fatty acids in rumen contents and the indices of acid-base homeostasis of blood were monitored in the subsequent 24 and/or 48 hours. The examinations showed that simultaneous administration of zeolite with sucrose failed to prevent the rise of metabolic acidosis but the drop in the indices of acid-base homeostasis was less severe, or was delayed by three to six hours. The dose of 0.45 g zeolite per kg l. w. was found to be insufficient for the prevention of a medium-severe or severe course of metabolic acidosis.
mesh_terms: D000138:Acidosis / Q000378:metabolism / Q000517:prevention & control / Q000662:veterinary*; D000538:Aluminum Silicates / Q000627:therapeutic use*; D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D012417:Rumen / Q000378:metabolism; D012756:Sheep; D012757:Sheep Diseases / Q000378:metabolism / Q000517:prevention & control*; D017641:Zeolites
chemical_list: D000538:Aluminum Silicates; D005227:Fatty Acids; D017641:Zeolites
vernacular_title: Vplyv zeolitu na experimentálne vyvolanú acidózu oviec.