Glucose-6-phosphatase as a marker for tumors of liver and kidney origin.
Glucose-6-phosphatase is primarily a liver and kidney enzyme. This enzyme was studied in various tumors, however, glucose-6-phosphatase activity was found only in tumors of liver, kidney, or adrenal origin. Glucose-6-phosphatase activity was useful in identifying the tissue origin of extrarenal Wilms'. Metastatic tumors within the liver or kidney that originated from other tissues did not have glucose-6-phosphatase activity. Therefore, it is suggested that glucose-6-phosphatase can be used as a specific enzyme marker for tumors of liver and kidney origin.
D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D003937:Diagnosis, Differential; D005952:Glucose-6-Phosphatase / Q000097:blood*; D006801:Humans; D007680:Kidney Neoplasms / Q000201:enzymology*; D008113:Liver Neoplasms / Q000201:enzymology*; D009369:Neoplasms / Q000201:enzymology; D009396:Wilms Tumor / Q000201:enzymology*
D005952:Glucose-6-Phosphatase