title: The mechanism of replication of hepatitis B virus: evidence of asymmetric replication of the two DNA strands.
abstract: In this study we have characterised the DNA replicative intermediates of hepatitis B virus and have shown that HBV-DNA replication is asymmetric. This pattern of HBV replication is similar to that reported for the related duck hepatitis virus (DHBV) and suggests the involvement of a similar reverse transcription process in HBV-DNA replication.
mesh_terms: D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000032:analysis*; D004587:Electrophoresis, Agar Gel; D006515:Hepatitis B virus / Q000254:growth & development*; D009693:Nucleic Acid Hybridization; D014779:Virus Replication
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes