[Chromolipid storage in alveolar macrophages: a distinctive mark for cigarette smokers].
Histological and cytological examinations of 188 autopsies--113 smokers and 75 non-smokers--established that cigarette smoke causes increase and multiplication of alveolar macrophages which contain inclusions of ceroid-like pigment. Acute death by fire, delayed asphyxia and putrefaction have no influence on the formation of these sudanophilic inclusions. The pigment is resistant to decomposition and lipid-solvents. It is possible to identify cigarette-smokers--even months after burial--by means of paraffin sections of lung tissue and proceeding with fat--staining methods.
D000293:Adolescent; D000328:Adult; D002566:Ceroid / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005554:Forensic Medicine; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure*; D008297:Male; D010860:Pigments, Biological / Q000032:analysis*; D011650:Pulmonary Alveoli / Q000166:cytology*; D012907:Smoking; D013223:Statistics as Topic
D002566:Ceroid; D010860:Pigments, Biological
Chromolipidspeicherung in Alveolarmakrophagen: ein Agnoszierungsmerkmal für Zigarettenraucher.