title: [Nucleoside mono- and nucleoside diphosphate kinase activities in rat liver and brain in radiation sickness].
abstract: Activity of nucleoside di- and nucleoside triphosphates metabolism enzymes in tissues of rats gamma-irradiated by a dose of 30 Gy was studied 0.5, 1, 3, 6 and 24 hours after the radiation effect. It is shown that the nucleoside  monophosphate kinase activity of the liver and brain is enhanced almost at all stages of the studies and the nucleoside diphosphate kinase activity is inhibited. A significant but reversible decrease of the nucleoside monophosphate kinase activity is observed in the liver 3 h later. By an end of the first day after irradiation the nucleoside mono- and nucleoside diphosphate kinase activities increase significantly both in the liver and brain.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology*; D005720:Gamma Rays; D008099:Liver / Q000201:enzymology*; D008297:Male; D009701:Nucleoside-Diphosphate Kinase / Q000528:radiation effects*; D009703:Nucleoside-Phosphate Kinase / Q000528:radiation effects*; D010770:Phosphotransferases / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014916:Whole-Body Irradiation
chemical_list: D010770:Phosphotransferases; D009703:Nucleoside-Phosphate Kinase; D009701:Nucleoside-Diphosphate Kinase
vernacular_title: Nukleozidmono- i nukleoziddifosfatkinaznaia aktivnost' pecheni i golovnogo mozga krys pri luchevoĭ bolezni.