Good response of a paraneoplastic neuromyopathy to cyclophosphamide.
The case history of a 59-year-old man with neuromyopathy and sicca syndrome, preceding the discovery of a small cell bronchial carcinoma for 16 months, is reported. This paraneoplastic neuromyopathy , resistant to steroid therapy, dramatically improved with cyclophosphamide treatment.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000188:drug therapy; D018288:Carcinoma, Small Cell / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009468:Neuromuscular Diseases / Q000188:drug therapy*; D010257:Paraneoplastic Syndromes / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use
D003520:Cyclophosphamide; D011241:Prednisone