Sequence of the amino-terminal part of enterotoxin from Clostridium perfringens type A: identification of points of trypsin activation.
The sequence of the first 66 amino acids of the amino-terminal part of the enterotoxin from Clostridium perfringens type A is presented. The trypsin activation of the enterotoxin involves hydrolysis of Lys15-Glu16 and Lys25-Thr26 bonds. The N-terminal sequence of the trypsin-activated enterotoxin has limited homology with the sequence of the N-terminal region of the cholera toxin B subunit.
D000595:Amino Acid Sequence; D002918:Chymotrypsin / Q000494:pharmacology; D003016:Clostridium perfringens / Q000032:analysis*; D003488:Cyanogen Bromide / Q000494:pharmacology; D004768:Enterotoxins; D014357:Trypsin / Q000494:pharmacology*
D004768:Enterotoxins; C035598:enterotoxin, Clostridium; D002918:Chymotrypsin; D014357:Trypsin; D003488:Cyanogen Bromide