title: Effects of dietary protein and fiber on growth and selected cholesterol responses of rats.
abstract: The effect of dietary protein and fiber on growth and metabolic parameters in blood serum, liver and kidney were determined in a 2 X 5 factorial experiment involving 40 Sprague-Dawley rats. Treatment variables were two dietary protein levels (16 and 24%) and five acid detergent fiber levels (6, 10, 16, 24 and 34%). No difference in growth rate of rats was found due to varying levels of either protein or fiber in the diet. Increasing the dietary protein level from 16 to 24% resulted in an 18.5% reduction in blood cholesterol. The dietary treatment containing 16% fiber influenced most metabolic parameters examined, including blood serum cholesterol, liver cholesterol and total lipid content in liver and kidney. Rats receiving the diet containing 16% fiber had the highest serum cholesterol (88.9 mg/dl) and the lowest liver cholesterol (4.4 mg/g) as compared with other fiber groups.
mesh_terms: D000821:Animal Feed; D000818:Animals; D002784:Cholesterol / Q000097:blood* / Q000378:metabolism; D004043:Dietary Fiber / Q000494:pharmacology*; D004044:Dietary Proteins / Q000494:pharmacology*; D006128:Growth; D007668:Kidney / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004043:Dietary Fiber; D004044:Dietary Proteins; D002784:Cholesterol