Interferon susceptibility of herpes simplex virus strains isolated from patients enrolled in clinical trials.
Herpes simplex virus type 1 strains isolated from patients who had received interferon in a clinical trial were not more resistant to human leukocyte interferon than strains derived from recipients of a placebo. The susceptibility of herpes simplex virus type 2 strains isolated from herpes genitalis was slightly less than that of herpes simplex virus type 1 strains causing herpes genitalis.
D005260:Female; D006558:Herpes Genitalis / Q000382:microbiology; D006561:Herpes Simplex / Q000382:microbiology; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D008297:Male; D008826:Microbial Sensitivity Tests; D018139:Simplexvirus / Q000187:drug effects*; D010948:Viral Plaque Assay
D007370:Interferon Type I