[Heterocyclic systems. IV. Synthesis and CNS activity of derivatives of 4H,6H-pyrrolo[1,2-a][4,1]-benzoxazepine].
The synthesis of derivatives of 4H,6H-pyrrolo[1,2-a][4,1]-benzoxazepine is described. These compounds were tested for activity on type (I) and (II) benzodiazepine receptors by several screening tests on mice.
D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis; D001381:Azepines / Q000138:chemical synthesis*; D001522:Behavior, Animal / Q000187:drug effects*; D005260:Female; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010077:Oxazepines / Q000138:chemical synthesis* / Q000494:pharmacology; D011597:Psychomotor Performance / Q000187:drug effects; D011619:Psychotropic Drugs / Q000138:chemical synthesis*; D011956:Receptors, Cell Surface / Q000378:metabolism; D011963:Receptors, GABA-A
D000927:Anticonvulsants; D001381:Azepines; D010077:Oxazepines; D011619:Psychotropic Drugs; D011956:Receptors, Cell Surface; D011963:Receptors, GABA-A
Sistemi eterociclici. NOta IV - Sintesi ed attività sul S.N.C. di derivati della 4H,6H-pirrolo[1,2-a][4.1]benzossazepina.