Genetic mapping of a mouse chromosomal locus required for mink cell focus-forming virus replication.
Mouse-hamster somatic cell hybrids were used to show that the recombinant mink cell focus-forming murine leukemia viruses and their ecotropic virus progenitors require different mouse chromosomes for replication. Mouse chromosome 1 was shown to carry the genetic information necessary for the replication of six different mink cell focus-forming isolates, and this gene, designated Rmc-1, was tentatively positioned at the distal end of the chromosome.
D000818:Animals; D002874:Chromosome Mapping; D006224:Cricetinae; D005796:Genes; D006822:Hybrid Cells; D009052:Leukemia Virus, Murine / Q000502:physiology*; D051379:Mice / Q000235:genetics; D008907:Mink; D014779:Virus Replication