Calmodulin level in whole blood correlates with the percentage of reticulocytes.
We studied the calmodulin-like activity (CaM) level in hemolyzed samples of whole blood after determining the percentage and absolute number of reticulocytes present. Twenty-six samples from 25 people with a range of reticulocyte counts were studied. CaM levels correlated with the percentage (r = 0.63, P less than .01) and absolute number (r = 0.64, P less than .01) of reticulocytes present, indicating that the calmodulin-like activity level in whole blood was inversely related to erythrocyte age.
D000328:Adult; D000368:Aged; D000755:Anemia, Sickle Cell / Q000097:blood; D002135:Calcium-Binding Proteins / Q000097:blood*; D002147:Calmodulin / Q000097:blood*; D004905:Erythrocyte Aging; D004906:Erythrocyte Count; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D012156:Reticulocytes
D002135:Calcium-Binding Proteins; D002147:Calmodulin; D005954:Glucosephosphate Dehydrogenase; D010727:Phosphoric Diester Hydrolases