title: Partial tertiary structure assignments for the beta-, gamma- and delta-subunits of the acetylcholine receptor on the basis of the hydrophobicity of amino acid sequences and channel location using single group rotation theory.
abstract: Four transmembrane segments from each of the beta-, gamma- and delta-protein subunits of the acetylcholine receptor (AChR) [Nature (1983) 301, 251-255], [Proc. Natl. Acad. Sci. USA (1983) 80, 1111-1115] have been selected on the basis of single group rotation (SGR) theory [Symp. Structure and Dynamics of Nucleic Acids and Proteins (Sept. 1982) abst. pp. 52-53], [Biochem. Biophys. Res. Commun. (1983) 111, 1022-1029] and the hydrophobicity of amino acid sequences. One helix from each subunit is assigned to the AChR ion channel. Criteria for the selection of ion channel elements are outlined.
mesh_terms: D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D007473:Ion Channels; D011487:Protein Conformation; D011950:Receptors, Cholinergic; D012995:Solubility
chemical_list: D007473:Ion Channels; D011950:Receptors, Cholinergic