Compartment analysis of the potassium fluxes in the cochlea.
The results obtained from tracer kinetics, measured by Konishi et al. (1978) and June (1979), are combined to construct a two-compartment model of the guinea-pig cochlea. The potassium fluxes are calculated using a mathematical two-compartment theory. For the basal turn, one finds a circulating flux between the endolymphatic and perilymphatic spaces of 190 pMol/min and 1 mm cochlea, whereas a minor value of 100 pmol/min/mm is calculated for the flux from the perilymphatic scales out of the cochlea.
D000818:Animals; D002199:Capillary Permeability; D003051:Cochlea / Q000378:metabolism*; D004710:Endolymph / Q000378:metabolism; D006168:Guinea Pigs; D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological; D010498:Perilymph / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*
D007473:Ion Channels; D011188:Potassium