title: [Pathology and physiology of microbes. III. Criteria for assessing functional states].
abstract: The study of different characteristics of the vital activity of microorganisms, made on type B Clostridium perfringens taken as an example, has disclosed the difficulty of evaluating the functional state of microorganisms only on the basis of the traditionally used characteristics of the population activity: the specific growth rate, the toxicity of the culture fluid and the antigenic properties of the culture. The economic and metabolic coefficients have been found to be the most suitable criteria for such evaluation; the state of the maximum physiological activity of the population is characterized by the maximum values of the economic coefficient and the minimum values of the metabolic coefficient. The minimum values of the economic coefficient and the maximum values of the metabolic coefficient are characteristic of the pathological state of the population.
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis; D001419:Bacteria / Q000276:immunology; D018407:Bacterial Physiological Phenomena; D001431:Bacteriological Techniques; D003016:Clostridium perfringens / Q000276:immunology / Q000502:physiology; D003470:Culture Media / Q000378:metabolism; D004734:Energy Metabolism; D005947:Glucose / Q000378:metabolism; D008433:Mathematics
chemical_list: D000942:Antigens, Bacterial; D003470:Culture Media; D005947:Glucose
vernacular_title: Patologiia i fiziologiia mikrobov. Soobshchenie III. Kriterii otsenki funktsional'nykh sostoianiĭ.