[Hereditary osteo-onychodysplasia. Histomorphometric bone study. Apropos of a case].
The authors report on a patient with hereditary osteo-onychodysplasia (HOOD). Osteoporosis was demonstrated upon histomorphologic bone examination. HOOD is a rare inherited disorder. Typical features include dysplasia of the nails, patellae, elbows and ilium. Nephropathy occurs in 48% of patients. Numerous renal histologic studies have led to the concept that the nail-patella syndrome is an inherited metabolic disorder affecting the connective tissue. Our findings from histomorphologic bone assessment bring further evidence in support of this hypothesis.
D000328:Adult; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics; D009261:Nail-Patella Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography
Ostéo-onycho-dysplasie héréditaire. Etude histomorphométrique osseuse. A propos d'un cas.