[Comparative study of the effects of sultopride and haloperidol in agitation states. 94 cases at the psychiatric infirmary of the Paris police headquarters].
We report the results of a comparative study of sultopride and haloperidol in two groups of 46 and 48 patients. The study was single-blind at first, then double-blind. It was carried out at the psychiatric infirmary of the central police station, run according to the law of June 30th, 1938, which allows to detain patients presenting with severe agitation during 24 hours or more for observation and treatment. The target symptom is psychomotor agitation. The purpose is to make a psychiatric interview possible without suppressing all the clinical manifestations or masking the patient's personality. The efficiency of both drugs seems comparable but is better with sultopride given initially in high dosages. As its side-effects are mild and are not aggravated when dosages are increased sultopride is the choice neuroleptic for the initial treatment of psychomotor agitation in patients admitted in the specific conditions of deferred emergencies.
D000077582:Amisulpride; D006220:Haloperidol / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D011595:Psychomotor Agitation / Q000188:drug therapy*; D013469:Sulpiride / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D013469:Sulpiride; D000077582:Amisulpride; D006220:Haloperidol
Etude comparative des effets du sultopride et de l'halopéridol dans les états d'agitation. Quatre-vingt-quatorze observations à l'Infirmerie Psychiatrique de la Préfecture de Police de Paris.