[Interaction of tetrodotoxin-sensitive structures of soluble cardiac muscle proteins with liposomes].
It is studied how conditions of soluble myocardium proteins interaction with liposomes provide formation of the channel-like structures with tetrodotoxin- and veratrine-dependent sodium permeability. The temperature is shown to influence the formation rate of neurotoxin-sensitive proteoliposomes. The veratrine effect on sodium permeability of proteoliposomes intensifies with the rise of temperature. Pretreatment of liposomes by veratrine prevents formation of tetrodotoxin sensitivity in proteoliposomes.
D000818:Animals; D002417:Cattle; D007473:Ion Channels / Q000502:physiology; D007700:Kinetics; D008081:Liposomes; D008954:Models, Biological; D009124:Muscle Proteins / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010539:Permeability; D011510:Proteolipids / Q000378:metabolism; D011817:Rabbits; D013696:Temperature; D013779:Tetrodotoxin / Q000494:pharmacology*; D014702:Veratrine / Q000494:pharmacology*
D007473:Ion Channels; D008081:Liposomes; D009124:Muscle Proteins; D011510:Proteolipids; C020485:proteoliposomes; D013779:Tetrodotoxin; D014702:Veratrine
O vzaimodeĭstvii tetrodotoksin-chuvstvitel'nykh struktur rastvorimykh belkov serdechnoĭ myshtsy s liposomami.