title: [Epidemiological study on the assay of antibodies to anti-TORCH agents and to HBV in a group of mother/child pairs in Palermo].
abstract: The TORCH group: toxoplasma, rubeola, cytomegalovirus (CMV), herpes virus hominis (HSV) and also the B-virus of hepatitis (HBV) determine congenital malformations in the newborns. For this reason, the Authors leaded an epidemiologic study testing with some antibodies (anti-TORCH and anti-HBV) the serum of groups of mother-newborn of the Obstetrical Clinic of Palermo. This study became manageable because now there are available high specific immunoenzymatic methods, for example ELISA, the passive haemoagglutination and the haemoagglutination-inhibition. In our people, high concentration of rubeola, HSV and CMV and very low concentration of toxoplasma and HBV are shown. The frequency of malformation is related with the subclinical infection. The Authors suggest to extend same investigation at an higher number of pregnant women to prevent these congenital malformations.
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D000013:Congenital Abnormalities / Q000382:microbiology; D003587:Cytomegalovirus / Q000276:immunology; D004812:Epidemiologic Methods; D005260:Female; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D008459:Measles virus / Q000276:immunology; D011247:Pregnancy; D018139:Simplexvirus / Q000276:immunology; D014122:Toxoplasma / Q000276:immunology
chemical_list: D000914:Antibodies, Viral
vernacular_title: Studio epidemiologico per la ricerca di anticorpi anti-agenti TORCH e di HBV in un gruppo di coppie madre/figlio a Palermo.