Deficient learning and memory in early and middle phases of multiple sclerosis.
Forty-three patients with multiple sclerosis showed disturbances in short-term memory, learning, and delayed recall which were associated with years of active disease (average was 4.5 years), age, presence of flareup, but not steroid/ACTH treatment. Unrecognised memory loss might be prevalent early in the natural history of multiple sclerosis and deserves neuropsychological assessment.
D000324:Adrenocorticotropic Hormone / Q000627:therapeutic use; D000328:Adult; D005260:Female; D006801:Humans; D007858:Learning / Q000502:physiology; D008297:Male; D008568:Memory / Q000502:physiology; D008570:Memory, Short-Term / Q000502:physiology; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000523:psychology*; D011597:Psychomotor Performance / Q000502:physiology; D013256:Steroids / Q000627:therapeutic use; D013997:Time Factors
D013256:Steroids; D000324:Adrenocorticotropic Hormone