[Effect of penicillin and the habitat medium in the body of bacterial carriers on the intercellular bonds in populations of the meningococcus and pertussis microbe].
The relationship of the bacterial cells in populations and their adhesion activity is at present one of the research priorities in microbiological studies. The stimulating effect of penicillin on the development of morphologically different intercellular bonds (IB) in populations of the pertussis causative agent and first of all derivatives or evaginates of the cell wall membranes was observed. Morphologically similar systems and polytubular IB were detected in populations of meningococcal strains isolated from carriers having no signs of the disease. Correlation between the after-effect of penicillin and the presence of the causative agent in bacterial carriers was shown. Unknown systems of interlacing tubular structures not directly bound with the cells, the walls of which were single contour membranes were determined in the meningococcal populations treated with penicillin. IB were observed in the population in the form of transpopulation cords. Morphologically different IB playing the role of specialized organelles might be considered as factors of the functional unity of the bacterial population as a multicellular system.
D001886:Bordetella pertussis / Q000187:drug effects* / Q000648:ultrastructure; D002353:Carrier State / Q000382:microbiology*; D004463:Ecology; D006801:Humans; D066298:In Vitro Techniques; D007365:Intercellular Junctions / Q000187:drug effects* / Q000648:ultrastructure; D007740:L Forms / Q000187:drug effects / Q000648:ultrastructure; D008585:Meningitis, Meningococcal / Q000382:microbiology*; D008854:Microscopy, Electron; D009305:Nasopharynx / Q000382:microbiology; D009345:Neisseria meningitidis / Q000187:drug effects* / Q000648:ultrastructure; D010406:Penicillins / Q000494:pharmacology*; D014917:Whooping Cough / Q000382:microbiology*
D010406:Penicillins
Vliianie penitsillina i sredy obitaniia v organizme bakterionositeleĭ na mezhkletochnye sviazi populiatsiĭ meningokokka i kokliushnogo mikroba.