[Major intolerance to carbamazepine. Acquired immunodepression or allergy?].
The authors report the case of an eight-year-old boy who developed erythroderma under carbamazepine. Other findings were enlarged lymph nodes, slight hepatic cytolysis, leuconeutropenia and decrease in the three classes of immunoglobulins. The immunosuppressive effect of the drug is recalled. Respective responsibility of immunosuppression and allergy is discussed.
D002220:Carbamazepine / Q000009:adverse effects*; D002648:Child; D003875:Drug Eruptions / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D007109:Immunity / Q000187:drug effects*; D008297:Male; D009503:Neutropenia / Q000139:chemically induced
D002220:Carbamazepine
Intolérance majeure à la carbamazépine. Immunodépression acquise ou allergie?