Transposon Tn5 encodes streptomycin resistance in nonenteric bacteria.
Strains of Caulobacter crescentus, Pseudomonas putida, Acinetobacter calcoaceticus, Rhizobium meliloti, and Rhodopseudomonas sphaeroides carrying the kanamycin resistance-encoding transposon Tn5 were 15 to 500 times more resistant to streptomycin than transposon-free strains. The streptomycin resistance determinant, which is separable from the kanamycin resistance determinant of Tn5, was not expressed in Escherichia coli or Klebsiella aerogenes.
D001419:Bacteria / Q000187:drug effects / Q000235:genetics*; D004251:DNA Transposable Elements; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000235:genetics; D007612:Kanamycin / Q000633:toxicity*; D007711:Klebsiella pneumoniae / Q000235:genetics*; D011549:Pseudomonas / Q000235:genetics; D012231:Rhizobium / Q000235:genetics; D012242:Rhodobacter sphaeroides / Q000235:genetics; D013045:Species Specificity; D013307:Streptomycin / Q000633:toxicity*
D004251:DNA Transposable Elements; D007612:Kanamycin; D013307:Streptomycin