[Influence of administration of pyridoxine on circadian rhythm of plasma ACTH, cortisol prolactin and somatotropin in normal subjects].
The influence of vitamin B6 in a dosage of 300 mg X 2 in 24 hrs, on circadian rhythm of plasmatic ACTH, cortisol, prolactin and somatotropin have been studied in 10 normal women. After vitamin B6 24 hrs pattern of ACTH and cortisol is unchanged; prolactin levels are slightly lower, in a statistically unsignificant proportion the night peak of growth hormone is higher in a statistically significant proportion (p. 0.05). The effect of vitamin B6 is likely to me mediated by dopaminergic receptors at hypothalamic level as previous studies by other Authors appear to prove.
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D002940:Circadian Rhythm / Q000187:drug effects; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D011736:Pyridoxine / Q000494:pharmacology*; D012016:Reference Values
D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013006:Growth Hormone; D011736:Pyridoxine; D006854:Hydrocortisone
Influenza della somministrazione di piridossina sul ritmo circadiano dell'acth, del cortisolo, della prolattina e del somatotropo plasmatici nei soggetti normali.