Steady state current noise from the intrinsic gating of inward rectifier channels.
Steady-state current noise from the intrinsic gating of inward rectifier channels in the eggs of the marine polychaete Neanthes arenaceodentata was recorded under voltage clamp conditions. Lorentzian-shaped power spectra with corner frequencies near 1 Hz and zero-frequency asymptotes of 1 - 5 X 10(-23) A2/Hz were obtained for test potentials 15-45 mV positive to EK in solutions containing 10-40 mM Ko. The spectra are compatible with the predictions of a three-state kinetic model for inward rectification in which the single channel rectification is independent of voltage. The single channel conductance derived from this interpretation is 8 pS with 40 mM Ko.
D000818:Animals; D004553:Electric Conductivity; D005260:Female; D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological; D010063:Ovum / Q000378:metabolism; D011077:Polychaeta / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*
D007473:Ion Channels; D011188:Potassium