Persistence of animal and human papovaviruses in renal and nervous tissues.
The papovavirus polyoma persists in the kidneys of mice after a primary infection. In addition polyomavirus was found in a small percentage of normal mouse brains and in brains of mice exhibiting rear leg paralysis. Human papovaviruses JCV and BKV DNA sequences were found in 10% and 34%, respectively, of normal human kidneys from 29 cadavers, but no sequences from either of these viruses were found in brain tissue from 22 of these same cadavers.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001739:BK Virus; D001921:Brain / Q000382:microbiology*; D002675:Child, Preschool; D004251:DNA Transposable Elements; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007577:JC Virus; D007668:Kidney / Q000382:microbiology*; D008297:Male; D051379:Mice; D008875:Middle Aged; D011120:Polyomavirus / Q000472:pathogenicity*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology; D014412:Tumor Virus Infections / Q000382:microbiology*
D004251:DNA Transposable Elements; D004279:DNA, Viral