Relationship between type specific antibodies to herpes simplex virus and type specificity in human sera.
A quantitative analysis was carried out on the relationship between type specific neutralizing antibodies to herpes simplex virus and the type specificity, using a mutual absorbing procedure. Forty-two samples were selected among human sera, on the basis of type specificity expressed by the value of II/I index. All sera with values of less than 90 of II/I index contained only type 1 specific antibody, while those with values over 111 contained only type 2 specific antibody. When the values were between 90 and 110, type 1 specific antibody was present in all, and type 2 specific antibody was present in some serum samples.
D000910:Antibodies, Heterophile / Q000276:immunology; D000914:Antibodies, Viral / Q000276:immunology*; D000918:Antibody Specificity; D003429:Cross Reactions; D006801:Humans; D018139:Simplexvirus / Q000276:immunology*
D000910:Antibodies, Heterophile; D000914:Antibodies, Viral