[Change in some properties of soluble cAMP-dependent protein kinase from rat myocardium during physical exercise].
During 1.5- and 3-months physical exercise the activity of soluble 3':5'-AMP-dependent protein kinase of the rat increases 2.4- and 4.6-fold, respectively. The maximal activity of the enzymes from heart muscles of control and experimental animals is observed at the same concentration of 3':5'-AMP (10(-6) M) and pH (6.8-7.0). The degree of changes in V and apparent Km for ATP and histone H2b depend on the duration of physical exercise. The changes in the properties of soluble 3':5'-AMP-dependent protein kinase suggest the participation of the enzyme in adaptation to systematic muscular activity.
D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology*; D006321:Heart / Q000502:physiology; D007700:Kinetics; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D005082:Physical Exertion; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats
D000242:Cyclic AMP; D011494:Protein Kinases
Izmenenie nekotorykh svoĭstv rastvorimoĭ cAMP-zavisimoĭ proteinkinazy miokarda krys pri trenirovke fizicheskimi nagruzkami.