Tricyclic-induced akathisia in patients taking conjugated estrogens.
Three patients taking conjugated estrogens developed akathisia induced by tricyclic antidepressants. The interaction between tricyclic antidepressants and conjugated estrogens could play a role in the development of akathisia.
D000328:Adult; D017109:Akathisia, Drug-Induced; D000639:Amitriptyline / Q000009:adverse effects / Q000494:pharmacology; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000494:pharmacology; D002997:Clomipramine / Q000009:adverse effects / Q000494:pharmacology; D004316:Doxepin / Q000009:adverse effects / Q000494:pharmacology; D004347:Drug Interactions; D004966:Estrogens, Conjugated (USP) / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006801:Humans; D008875:Middle Aged
D000929:Antidepressive Agents, Tricyclic; D004966:Estrogens, Conjugated (USP); D004316:Doxepin; D000639:Amitriptyline; D002997:Clomipramine