title: [Long-term study of 150 mg. Bi-Profenid in patients followed at the Department of Rheumatology of Cochin Hospital].
abstract: The effectiveness and tolerance of Bi-Profenid 150 mg (two tablets a day) was evaluated in 37 patients under long-term treatment by retrospective analysis of case records. Mean duration of therapy was 15.5 months. Over this period improvement in the usual surveillance criteria was recorded. In 6 patients the "therapeutic follow-up test" allowed to decrease dosage to one tablet a day. Conversely, attempts at discontinuing the drug were followed by recurrence of pain. Tolerance was evaluated as excellent in 89% of cases and the only recorded side-effects were gastrointestinal.
mesh_terms: D000328:Adult; D000368:Aged; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D010666:Phenylpropionates / Q000627:therapeutic use*; D012189:Retrospective Studies; D012216:Rheumatic Diseases / Q000188:drug therapy*
chemical_list: D003692:Delayed-Action Preparations; D010666:Phenylpropionates; D007660:Ketoprofen
vernacular_title: Etude à long terme du Bi-Profénid 150 mg chez les patients suivis dans le Service de Rhumatologie de l'Hôpital Cochin.