title: Changes in activities of fucokinase and fucosyltransferase in rat hippocampus after acquisition of a brightness discrimination reaction.
abstract: Activities of enzymes involved in utilization of the glycoprotein precursor L-fucose (fucokinase and fucosyltransferase) were studied in rat hippocampal tissue after acquisition of a brightness discrimination reaction. Fucokinase activity was increased immediately after training, while fucosyltransferase revealed decreased values. However, 7 hr after training fucokinase activity showed normal values, while fucosyltransferase activity rose in trained animals over active and passive controls. The results are discussed in the light of a regulatory role that fucokinase and fucosyltransferase may play in fucose utilization under altered functional conditions.
mesh_terms: D000818:Animals; D003216:Conditioning, Operant; D004193:Discrimination Learning; D005647:Fucosyltransferases / Q000378:metabolism*; D006602:Hexosyltransferases / Q000378:metabolism*; D006624:Hippocampus / Q000201:enzymology / Q000502:physiology*; D007700:Kinetics; D008297:Male; D010770:Phosphotransferases / Q000378:metabolism*; D017853:Phosphotransferases (Alcohol Group Acceptor); D010775:Photic Stimulation; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005647:Fucosyltransferases; D006602:Hexosyltransferases; C020559:Glycoprotein 6-alpha-L-fucosyltransferase; D010770:Phosphotransferases; D017853:Phosphotransferases (Alcohol Group Acceptor); C020153:fucokinase