title: Transumbilical portal vein catheterization and insulin analysis in an infant with hypoglycemia.
abstract: We performed transumbilical portal vein catheterization and sampled portal blood selectively to carry out immunoreactive insulin (IRI) analyses in a 7-month-old girl with hypoglycemia. The IRI concentration was highest in the mid-portion of the splenic vein. Although no tumor was found at surgery, 70 per cent of the caudal pancreas was resected above the superior mesenteric vein to a point determined by preoperative investigations. Pathologic examination of the resected specimen indicated nesidioblastosis. There have been no postoperative hypoglycemic symptoms. Our technique is efficacious in reaching a diagnosis of infantile hypoglycemia.
mesh_terms: D007516:Adenoma, Islet Cell / Q000175:diagnosis; D002404:Catheterization / Q000379:methods*; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000378:metabolism*; D007223:Infant; D007328:Insulin / Q000032:analysis*; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D011169:Portal Vein; D014471:Umbilical Veins
chemical_list: D007328:Insulin