Cytomegalovirus encephalitis occurring after bone marrow transplantation.
4 months after a bone marrow transplantation performed for acute lymphocytic leukaemia, a 28-year-old man had encephalitis. A brain CT scan revealed bilateral and symmetrical temporal hypodense areas. Serological studies revealed a recent CMV conversion in serum and a higher conversion in cerebral spinal fluid. All other viral antibodies remained at low levels, especially for herpes simplex virus. Because of a high incidence of CMV infection after bone marrow transplantation, the responsibility of CMV as the cause of the encephalitis is discussed.
D000328:Adult; D016026:Bone Marrow Transplantation; D001921:Brain / Q000000981:diagnostic imaging; D003586:Cytomegalovirus Infections; D004660:Encephalitis / Q000209:etiology*; D005260:Female; D006558:Herpes Genitalis / Q000209:etiology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy; D008297:Male; D011877:Radionuclide Imaging; D013601:T-Lymphocytes