[A specific histological marker of undifferentiated carcinoma of the nasopharynx. The ACIF (Anti-Complement Immunofluorescence) test].
The relationship between E.B.V. infection and nasopharyngeal carcinomas can be used as a marker of these tumors (A.C.I.F. test). The method reveals the nuclear antigen (E.B.N.A.) by anti complement immunofluorescence. It was applied to 102 patients with N.P.C. and was found positive only in undifferentiated carcinoma (U.C.N.T.). This "marker" can be useful in search of primary from lymph node metastasis.
D000956:Antigens, Viral / Q000032:analysis*; D002277:Carcinoma / Q000276:immunology / Q000473:pathology*; D019309:Epstein-Barr Virus Nuclear Antigens; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006651:Histocytochemistry; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D009367:Neoplasm Staging
D000956:Antigens, Viral; D019309:Epstein-Barr Virus Nuclear Antigens
Un marqueur histologique spécifique du carcinome indifféréncié de type naso-pharyngé (U.C.N.T.). Le test A.C.I.F.