title: Identification and characterization of the glucuronide metabolite of diethyldithiocarbamic acid in the bile from the isolated perfused rat liver by gas chromatography and mass spectrometry.
abstract: The glucuronide metabolite of diethyldithiocarbamic acid has been identified in bile from the isolated perfused rat liver. The bile was chromatographed on XAD-2 resin, pertrimethylsilylated with BSTAF + 1% TMCS, identified and characterized by combined gas chromatography and mass spectrometry. The glucuronide characterized as the silylated derivative showed no molecular ion but a small fragment ion at M-15(598).
mesh_terms: D000818:Animals; D001646:Bile / Q000378:metabolism*; D004050:Ditiocarb / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D005965:Glucuronates / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013859:Thiocarbamates / Q000378:metabolism*
chemical_list: D005965:Glucuronates; D013859:Thiocarbamates; D004050:Ditiocarb