Identification of the cell types in the rostral pars distalis of the pituitary gland of the catfish, Clarias batrachus (Linn).
The cells in the rostral pars distalis (RPD) of the hypophysis of the catfish, Clarias batrachus were distinguished into 2 types by tinctorial affinities, and their functional significance was ascertained experimentally. The lead haematoxylin (PbH)-positive cells of the RPD, herein referred to as the cell type 1, are in the form of a 3-8 cell layer thick palisade along the border between the neurohypophysis (NH) and the RPD. Administration of metopirone caused significant stimulatory changes in these cells, whereas injection of ACTH, hydrocortisone or dexamethasone resulted in marked regression suggesting their ACTH-secreting nature. The type 2 cells constitute a major part of the RPD and are erythrosinophilic in nature. They showed regressive changes after immersion of the catfish in sodium chloride solution and distilled water, and a similar change was observed after injection of prolactin which indicates their prolactin-secreting nature.
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects; D003594:Cytoplasmic Granules / Q000187:drug effects; D003907:Dexamethasone / Q000494:pharmacology; D005260:Female; D005399:Fishes / Q000033:anatomy & histology*; D006854:Hydrocortisone / Q000031:analogs & derivatives / Q000494:pharmacology; D008297:Male; D010903:Pituitary Gland, Anterior / Q000166:cytology* / Q000187:drug effects; D012965:Sodium Chloride / Q000494:pharmacology
C021650:hydrocortisone acetate; D012965:Sodium Chloride; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone