title: An active cytochrome c oxidase that has no tightly bound cardiolipin.
abstract: Bovine and dogfish (Squalus acanthias) heart submitochondrial particles and cytochrome c oxidase (EC 1.9.3.1) were prepared. Biphasic Eadie--Hofstee plots from steady-state polarographic assays were obtained for both species. Phospholipid analyses indicated that cardiolipin was absent from this active dogfish enzyme.
mesh_terms: D000818:Animals; D001665:Binding Sites; D002308:Cardiolipins / Q000378:metabolism*; D002417:Cattle; D004284:Dogfish; D003576:Electron Transport Complex IV / Q000378:metabolism*; D007700:Kinetics; D008929:Mitochondria, Heart / Q000201:enzymology; D013367:Submitochondrial Particles / Q000201:enzymology
chemical_list: D002308:Cardiolipins; D003576:Electron Transport Complex IV