title: [Early changes in the nucleoside diphosphate kinase activity of the rat brain and liver during whole body gamma irradiation in an absolutely lethal dose].
abstract: Nucleoside diphosphatkinase activity in mitochondria and post-mitochondrial supernatant fraction from brain and liver tissues was shown to decrease sharply during the first 60 min after total-body gamma-irradiation of rats with an absolutely lethal dose (30 Gy). A significant increase in the enzyme activity was registered 3 and 24 h following irradiation. Changes in nucleoside diphosphatkinase activity were more pronounced in mitochondria (particularly in liver mitochondria) than in the supernatant fraction.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D008928:Mitochondria / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D009701:Nucleoside-Diphosphate Kinase / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000201:enzymology* / Q000401:mortality; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D010770:Phosphotransferases; D009701:Nucleoside-Diphosphate Kinase
vernacular_title: Rannie izmeneniia nukleoziddifosfatkinaznoĭ aktivnosti golovnogo mozga i pecheni krys pri obshchem gamma-obluchenii v absoliutno letal'noĭ doze.