title: ELISA antibodies to cytomegalovirus in pregnant patients: prevalence in and correlation with spontaneous abortion.
abstract: Prevalence of seroimmunity to cytomegalovirus (CMV) infection was tested by detecting ELISA IgG antibodies in 230 pregnant subjects from low socioeconomic backgrounds. Seroimmunity increased from 64.3% to 92.0% between the ages 15-20 and 35-40. Furthermore, ELISA IgM antibodies were detected during hospitalization in a group of 56 women whose pregnancies ended in spontaneous abortion and in a paired matched-control group. The overall percentage of IgM-positive reactions was 5.35% in the group with abortion. The percentage for only second trimester abortions amounted to 18.75%. There was no IgM-positive reaction in the control group.
mesh_terms: D000022:Abortion, Spontaneous / Q000276:immunology* / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000150:complications; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D011247:Pregnancy
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M