Effect of estradiol on alpha- and beta-adrenoceptor density in medial basal hypothalamus, cerebral cortex and pineal gland of ovariectomized rats.
Estradiol treatment of ovariectomized rats resulted in a significant increase in beta-adrenoceptor density in the medial basal hypothalamus (MBH) without affecting the affinity for the radioactive ligand. Neither MBH alpha-adrenoceptors nor alpha- or beta-adrenoceptors in the cerebral cortex, or beta-adrenoceptors in the pineal gland, were affected by estradiol injection.
D000818:Animals; D001921:Brain / Q000187:drug effects*; D002369:Castration; D002540:Cerebral Cortex / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D007033:Hypothalamus, Middle / Q000187:drug effects; D010053:Ovary / Q000502:physiology; D010870:Pineal Gland / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D004958:Estradiol