Loss of membrane B2 microglobulin in eccrine porocarcinoma. Its association with the histopathologic and clinical criteria of malignancy.
A sensitive immunoperoxidase method employs a new chicken anti-B2-microglobulin (B2M) antibody for use on paraffin sections. The method demonstrates the loss of B2M from the cell membranes of malignant eccrine poromas , and this is correlated with the histopathologic and clinical criteria of malignancy.
D006607:Adenoma, Sweat Gland / Q000473:pathology*; D000818:Animals; D000906:Antibodies; D002462:Cell Membrane / Q000032:analysis; D002645:Chickens; D004439:Eccrine Glands; D007124:Immunoenzyme Techniques; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D013545:Sweat Glands; D001613:beta 2-Microglobulin / Q000032:analysis* / Q000276:immunology
D000906:Antibodies; D001613:beta 2-Microglobulin