Hepatoma after thorotrast. Morphological and autoradiographic data.
Two women, respectively given thorotrast 30 and 40 years ago, died of hepatoma. The spleen and liver of one and the liver of the other were studied by morphological, macro- and micro-autoradiographic methods. The part played by thorotrast in the neoplasic process and its effect on the mechanism of tumour induction are discussed.
D000368:Aged; D001345:Autoradiography; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D003594:Cytoplasmic Granules / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology / Q000528:radiation effects*; D008113:Liver Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D013154:Spleen / Q000473:pathology / Q000528:radiation effects*; D013158:Splenic Diseases / Q000473:pathology*; D013911:Thorium Dioxide / Q000009:adverse effects*
D013911:Thorium Dioxide