Recovery of malignant tumor cells from the right atrium during hepatic resection for hepatocellular carcinoma.
Tumor cells were recovered from the right atrium in three of five patients during hepatic resection for hepatocellular carcinoma. Mechanical factors during blunt mobilization and rotation of the hepatic tumor appeared to be responsible for tumor dislodgement into the venous circulation. Tumor embolization to the lungs may be one of the important reasons for the poor results of surgery in this disease. Two possible technical and therapeutic modifications are suggested to prevent or neutralize this phenomenon.
D001769:Blood; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D005260:Female; D006325:Heart Atria; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008175:Lung Neoplasms / Q000209:etiology / Q000556:secondary; D008297:Male; D008722:Methods; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating; D010865:Pilot Projects