title: [Analysis and evaluation of carcinogenic polycyclic aromatic hydrocarbons from the view of food hygiene and toxicology--a survey].
abstract: The contamination of foods is technologically induced by smoke gases (smoking, grilling, drying) and also due to environmental factors such as air and soil, soil conditioners, migration from plastics etc. The author presents and discusses the major problems concerning the accurate analysis of smallest amounts (micrograms/kg of food) of polycyclic aromatic hydrocarbons (PAH). Such problems occur in the separation from he matrix and the clean-up of the PAH, as well as in their identification and determination. Benzo[a]pyrene - under certain preconditions internationally accepted as the reference standard of PAH - is ingested by the GDR citizens in an order of magnitude ranging from 0.2 to 1.0 mg per annum; this corresponds to a daily intake varying within 0.5 and 2.5 micrograms. It is particularly difficult and as yet not possible to establish scientifically founded maximum tolerances for cancerogenic substances in foods which exclude a risk to man. The establishment of tolerances in the sense of a "socially acceptable level of risk" (which does not mean physiological safety) is recommended. Controlled tolerances would enable the legislator to aim at the optimum reduction or exclusion of the cancerogenic noxious agent in the framework of technical and economic possibilities.
mesh_terms: D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000032:analysis; D002273:Carcinogens / Q000008:administration & dosage / Q000032:analysis*; D002274:Carcinogens, Environmental / Q000032:analysis; D005506:Food Contamination / Q000032:analysis*; D005511:Food Handling / Q000592:standards; D005859:Germany, East; D006801:Humans; D008452:Maximum Allowable Concentration; D008722:Methods; D011083:Polycyclic Compounds / Q000008:administration & dosage / Q000032:analysis* / Q000633:toxicity
chemical_list: D001580:Benzopyrenes; D002273:Carcinogens; D002274:Carcinogens, Environmental; D011083:Polycyclic Compounds; D001564:Benzo(a)pyrene
vernacular_title: Analytik und Bewertung cancerogener polycyclischer aromatischer Kohlenwasserstoffe aus lebensmittelhygienisch-toxikologischer Sicht - Eine Ubersicht.