beta-endorphin acting on the brainstem is involved in the antihypertensive action of clonidine and alpha-methyldopa in rats.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D003000:Clonidine / Q000494:pharmacology*; D003900:Desoxycorticosterone; D004723:Endorphins / Q000494:pharmacology / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects; D006973:Hypertension / Q000503:physiopathology*; D006977:Hypertension, Renal / Q000503:physiopathology*; D007106:Immune Sera; D008297:Male; D008750:Methyldopa / Q000494:pharmacology*; D009271:Naltrexone / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011922:Rats, Mutant Strains; D001615:beta-Endorphin
D004723:Endorphins; D007106:Immune Sera; D003900:Desoxycorticosterone; D008750:Methyldopa; D009271:Naltrexone; D001615:beta-Endorphin; D003000:Clonidine