Antibodies to Coronavirus OC 43 strain in the population of North-Eastern Hungary.
Monthly 120 serum samples were collected from healthy and clinically ill residents of North-Eastern Hungary in the years 1980 and 1981. Haemagglutination-inhibiting antibody to the strain Coronavirus OC 43 was detected in 58% of the 2881 samples. The rate of positive sera was the lowest, 23%, between 7 and 11 months of age and reached the peak of 70% between 15 and 19 years. It did not rise further with age. Paired sera was tested from 405 patients suffering from various diseases. A titre rise was shown in 23 patients; 12 of these were suffering from acute respiratory disease, another 7 showed simultaneous exacerbation of bronchial asthma or spastic bronchitis.
D000293:Adolescent; D000328:Adult; D000375:Aging; D000914:Antibodies, Viral / Q000032:analysis*; D001249:Asthma / Q000150:complications; D001991:Bronchitis / Q000150:complications; D002648:Child; D002675:Child, Preschool; D003332:Coronaviridae / Q000276:immunology*; D003333:Coronaviridae Infections / Q000150:complications / Q000453:epidemiology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D006814:Hungary; D007223:Infant; D012141:Respiratory Tract Infections / Q000453:epidemiology*
D000914:Antibodies, Viral