title: Restriction map and location of mutations on the genome of bacteriophage Hp1c1 of Haemophilus influenzae Rd.
abstract: A physical map of the 32.4-kb chromosome of the Haemophilus influenzae bacteriophage Hp1c1 has been constructed, using the cleavage sites of eight restriction endonucleases. Two temperature-sensitive mutations have also been localized on the phage chromosome. The phage DNA exhibited an affinity for the specific DNA receptor of Haemophilus transformation approx. 1.5-fold higher than that obtained with bulk chromosomal DNA of H. influenzae.
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D006193:Haemophilus influenzae / Q000235:genetics*; D009154:Mutation; D011956:Receptors, Cell Surface / Q000378:metabolism; D014170:Transformation, Genetic
chemical_list: C033365:DNA receptor; D004279:DNA, Viral; D011956:Receptors, Cell Surface; D004262:DNA Restriction Enzymes