Evidence that the alpha 2HS glycoprotein receptor and the Epstein-Barr virus nuclear antigen (EBNA) are identical.
Evidence is presented which suggests that the alpha 2HS glycoprotein (alpha 2HS) receptor on lymphocytes transformed by Epstein-Barr virus (EBV) and the EBV-determined nuclear antigen (EBNA) are immunologically related, and may be identical. Western blotting, using both anti-EBNA and anti-alpha 2HS receptor serum identified a similar Mr 48 000 component in labelled detergent-solubilized transformed cell supernatants. The Mr 48 000 component recognized by anti-EBNA serum had a pI between 7-8, similar to that reported for the alpha 2HS receptor.
D000956:Antigens, Viral / Q000302:isolation & purification*; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism* / Q000382:microbiology; D001798:Blood Proteins / Q000378:metabolism*; D002472:Cell Transformation, Viral; D055598:Chemical Phenomena; D002621:Chemistry; D003902:Detergents; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D019038:Platelet Glycoprotein GPIb-IX Complex; D010980:Platelet Membrane Glycoproteins; D011956:Receptors, Cell Surface / Q000302:isolation & purification*; D012995:Solubility; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; D000956:Antigens, Viral; D001798:Blood Proteins; D003902:Detergents; D019038:Platelet Glycoprotein GPIb-IX Complex; D010980:Platelet Membrane Glycoproteins; D011956:Receptors, Cell Surface; D060749:alpha-2-HS-Glycoprotein; C032193:glycoprotein receptor GPIb-IX