Enzymes of peripheral blood neutrophils in patients with cancer of the stomach.
In 25 patients (10 women and 15 men) aged 37 to 68 years activity of the following enzymes has been determined by the use of semiquantitative cytochemical methods: acid and alkaline phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase and myeloperoxidase. Additionally the content of glycogen and lipids has been determined in the cells studied. An increase of the myeloperoxidase and acid phosphatase activity and a decrease of the glycogen and the lipid content has been stated in neutrophils of the patients. Above alterations may reflect antitumor reactivity of neutrophils or nonspecific neutrophil response against inflammatory changes accompanying the tumor area.
D000118:Acetylglucosaminidase / Q000097:blood; D000135:Acid Phosphatase / Q000097:blood; D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D005260:Female; D005966:Glucuronidase / Q000097:blood; D006003:Glycogen / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000032:analysis / Q000201:enzymology*; D009195:Peroxidase / Q000097:blood; D013274:Stomach Neoplasms / Q000097:blood*
D008055:Lipids; D006003:Glycogen; D009195:Peroxidase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005966:Glucuronidase; D000118:Acetylglucosaminidase