title: Changes of lung water and cardiovascular parameters during neurosurgical procedures associated with various types of infusion.
abstract: With the Swan-Ganz catheter and double indicator technique cardiovascular parameters and lung water were measured in 16 neurosurgical procedures. Five hundred millilitres of whole blood, Manitol or Fluosol-DA, or 1000 ml of lactate-Ringer solution was infused within 30 min, and various parameters were estimated and analysed. Extravascular lung water did not change with either solutions. Fluosol-DA showed the most powerful pressure effects. With whole blood and Fluosol DA, cardiac output and oxygen availability increased. Marked hemodilution was observed with the infusion of either Manitol, Fluosol-DA or lactate-Ringer solution, but only Fluosol-DA insured adequate oxygen supply to tissues by increase in oxygen capacity in blood. Fluosol-DA proved to be one of the suitable colloidal solutions to improve the hemodynamics and hemodilution during operation.
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D001834:Body Water / Q000032:analysis*; D001921:Brain / Q000601:surgery*; D002302:Cardiac Output; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D006438:Hemodilution; D006439:Hemodynamics; D006801:Humans; D008168:Lung / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood
chemical_list: D010100:Oxygen