New perspectives on vitamin D.
Our perception of vitamin D has evolved since the early part of this century. As an active, dihydroxylated metabolite vitamin D is acknowledged today not as an essential dietary factor but rather as a major calciotropic hormone. This paper summarizes current understanding of the formation and action of vitamin D in health and disease. The importance of laboratory assessment of serum vitamin D metabolites in the diagnosis and management of disorders of calcium and phosphorus metabolism is discussed.
D000328:Adult; D000818:Animals; D002118:Calcium / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002648:Child; D002762:Cholecalciferol / Q000096:biosynthesis; D004285:Dogs; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010018:Osteomalacia / Q000209:etiology; D010280:Parathyroid Glands / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D011956:Receptors, Cell Surface; D012279:Rickets / Q000188:drug therapy / Q000209:etiology*; D064030:S100 Calcium Binding Protein G / Q000378:metabolism; D014807:Vitamin D / Q000096:biosynthesis / Q000097:blood* / Q000378:metabolism; D014808:Vitamin D Deficiency
D011956:Receptors, Cell Surface; D064030:S100 Calcium Binding Protein G; D014807:Vitamin D; D002762:Cholecalciferol; D002118:Calcium