The effect of dietary supplementation with gamma-linolenic acid on the growth of induced tumours in rats.
In two identical experiments involving a total of 40 rats the effect of daily dietary gamma-linolenic acid (GLA) supplementation on induced tumour growth was investigated. It was found that GLA supplementation did not have an effect on tumour induction, tumour growth or survival time. The validity of the model used, infection of rats with human hepatoma cells, could be questioned.
D000284:Administration, Oral; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D005527:Food, Fortified; D008042:Linolenic Acids / Q000008:administration & dosage* / Q000494:pharmacology; D008114:Liver Neoplasms, Experimental / Q000473:pathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D017965:gamma-Linolenic Acid
D000970:Antineoplastic Agents; D008042:Linolenic Acids; D017965:gamma-Linolenic Acid