Parallel regulation of cAMP phosphodiesterase and phosphatase activities in turimycin fermentations.
Phosphate limitation induces the turimycin biosynthesis as well as the cAMP phosphodiesterase and phosphatase. The results are discussed in connection with the observation of general high activities of dephosphorylating enzymes and low concentrations of phosphorylated intermediates under conditions of phosphate limitation and secondary product biosynthesis, respectively.
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000096:biosynthesis*; D000242:Cyclic AMP / Q000378:metabolism; D005285:Fermentation; D007933:Leucomycins / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000096:biosynthesis*; D013302:Streptomyces / Q000378:metabolism*
D007933:Leucomycins; D010710:Phosphates; C011138:turimycin; D000242:Cyclic AMP; D010744:Phosphoric Monoester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases