title: [Cushing's disease. Current data on its course and treatment].
abstract: Recent developments in the treatment of Cushing's disease, particularly the trans-sphenoidal microadenomectomy, have prompted a survey of the pathophysiological theories of ACTH hypersecretion in this condition. The results of the trans-sphenoidal approach are reported and the post-surgical evolution (success failure or recurrence) are discussed. It is emphasized that a long fellow up is essential to assess the efficacy of this therapeutic approach.
mesh_terms: D000236:Adenoma / Q000503:physiopathology; D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D003480:Cushing Syndrome / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000503:physiopathology; D013997:Time Factors
chemical_list: D000324:Adrenocorticotropic Hormone
vernacular_title: Maladie de Cushing. Données actuelles sur l'évolution et le traitement.