[Cimetidine treatment of primary hyperparathyroidism].
Since Sherwood's report in 1979, contradictory findings have been published with regards to the treatment of primary hyperparathyroidism with cimetidine. We studied 16 patients with primary hyperparathyroidism treated with 1,200 mg of Cimetidine and followed-up clinically and biochemically. A decrease in serum calcium and urinary CAMP was observed after the fourth week of cimetidine therapy with no significant change in parathormone levels. In none of the cases did Cimetidine seem to provide a treatment of hyperparathyroidism, a condition which remains curable with surgery.
D002118:Calcium / Q000097:blood; D002927:Cimetidine / Q000627:therapeutic use*; D000242:Cyclic AMP / Q000652:urine; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000188:drug therapy* / Q000378:metabolism / Q000601:surgery; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011300:Preoperative Care
D010281:Parathyroid Hormone; D010758:Phosphorus; D002927:Cimetidine; D000242:Cyclic AMP; D002118:Calcium
Traitement par la cimétidine de l'hyperparathyroïdie primitive.