[Thyroid hormones in alcoholic cirrhosis before and after alcohol withdrawal].
In a controlled study, the authors have assayed the serum values of thyroid hormones, TSH, reverse T3 (rT3) and the T4/TBG ratio in patients with alcoholic liver cirrhosis before and after 15 days of total abstinence from alcohol. Before abstinence, they show a significant decrease of T3 and a significant increase of r T3. Only T3 values are correlated to the clinical and biological signs of liver cirrhosis. The T3 and rT3/T3 ratio allow a good evaluation of the severity of the cirrhotic condition. The study, after abstinence from alcohol, shows an improvement of both biological abnormalities and T3, rT3, rT3/T3 values. Pathogenic mechanisms of these disturbances are discussed and therapeutic prospects considered.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013997:Time Factors
D013963:Thyroid Hormones; D013972:Thyrotropin
Les hormones thyroïdiennes dans la cirrhose éthylique avant et après sevrage alcoolique.