title: Pathological rupture of the spleen associated with hepatitis A.
abstract: Spontaneous rupture of the spleen refers to rupture of a normal spleen in the absence of trauma. Atraumatic rupture of a diseased spleen is termed pathological rupture and has been described in a variety of pathological conditions. This report describes a case of pathological splenic rupture associated with hepatitis A confirmed by positive IgM antibodies. To the best of our knowledge, this case represents the sole verified example of this previously unrecognized life-threatening complication of hepatitis.
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D006506:Hepatitis A / Q000150:complications* / Q000175:diagnosis; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000209:etiology*
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M