A novel 125I radioimmunoassay for the analysis of delta 9-tetrahydrocannabinol and its metabolites in human body fluids.
A cannabinoid radioimmunoassay (RIA) that detects some of the major delta 9-THC metabolites is developed and evaluated for use in forensic science. It incorporates a novel 125I radiotracer, is sensitive, reliable, relatively quick, and simple to use. The RIA uses a commercially available antiserum and detects a number of cannabinoid metabolites, including delta 9-THC-11-oic acid and its glucuronide conjugate in biological fluids. The method was successfully applied to the analysis of blood and urine samples submitted for forensic analysis.
D001826:Body Fluids / Q000032:analysis*; D003429:Cross Reactions; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000032:analysis*; D005554:Forensic Medicine; D006801:Humans; D007124:Immunoenzyme Techniques; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay / Q000379:methods*
D007457:Iodine Radioisotopes; C016780:11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; D013759:Dronabinol