[Mobility of free radicals connected with serum albumins at 30-230 K].
This paper presents experimental results of inner dynamics study of human serum albumin by a series of physical methods: a) the method of radical pairs recombination based on measuring of recombination rate of radical pairs included to surface layers of a protein globule; b) the method of spin labels with saturation transfer technique. The complex of methods used in this work permits to measure the mobility of physical labels and environment matrix in a wide correlation frequency range 10(-4)-5.10(10) s-1 in 30-230 K temperature range. The analysis of the data obtained allows to make conclusions on the molecular mobility in surface layers of a protein globule under different conditions.
D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D005615:Freezing; D006801:Humans; D011487:Protein Conformation; D012709:Serum Albumin / Q000378:metabolism*
D005609:Free Radicals; D012709:Serum Albumin
Izuchenie podvizhnosti svobodnykh radikalov, sviazannykh s syvorotochnymi al'buminami pri 30-230 K.