Serum alpha-galactosidase activity in children with Duchenne-type muscular dystrophy and in gene carriers.
Serum alpha-galactosidase activity was studied in 21 control children, 15 children with Duchenne muscular dystrophy, and in 8 gene carrier mothers. In both the DMD hemi- and the heterozygous groups a significant increase of alpha-galactosidase activity was demonstrated.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D005696:Galactosidases / Q000097:blood*; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000201:enzymology / Q000235:genetics*; D000519:alpha-Galactosidase / Q000097:blood*
D003402:Creatine Kinase; D005696:Galactosidases; D000519:alpha-Galactosidase