title: Hepatoma after thorotrast. Morphological and autoradiographic data.
abstract: Two women, respectively given thorotrast 30 and 40 years ago, died of hepatoma. The spleen and liver of one and the liver of the other were studied by morphological, macro- and micro-autoradiographic methods. The part played by thorotrast in the neoplasic process and its effect on the mechanism of tumour induction are discussed.
mesh_terms: D000368:Aged; D001345:Autoradiography; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D003594:Cytoplasmic Granules / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology / Q000528:radiation effects*; D008113:Liver Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D013154:Spleen / Q000473:pathology / Q000528:radiation effects*; D013158:Splenic Diseases / Q000473:pathology*; D013911:Thorium Dioxide / Q000009:adverse effects*
chemical_list: D013911:Thorium Dioxide