title: Proton irradiation and endometriosis.
abstract: Female rhesus monkeys given single total-body exposures of protons of varying energies developed endometriosis at a frequency significantly higher than that of nonirradiated animals of the same age. The minimum latency period was 7 years after exposure. The doses and energies of the radiation received were within the range that could be received by an aircrew member in near-earth orbit during a random solar flare event, leading to the conclusion that endometriosis should be a consideration in assessing the risk of delayed radiation effects in female crewmembers.
mesh_terms: D000337:Aerospace Medicine; D000818:Animals; D004715:Endometriosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D008251:Macaca; D008253:Macaca mulatta; D011522:Protons; D011829:Radiation Dosage; D013997:Time Factors; D014916:Whole-Body Irradiation
chemical_list: D011522:Protons