Loss of antidepressant effect with long-term monoamine oxidase inhibitor treatment without loss of monoamine oxidase inhibition.
D006916:5-Hydroxytryptophan / Q000032:analysis; D001923:Brain Chemistry; D003866:Depressive Disorder / Q000188:drug therapy*; D004361:Drug Tolerance; D006801:Humans; D008996:Monoamine Oxidase Inhibitors; D009638:Norepinephrine / Q000032:analysis; D010624:Phenelzine / Q000008:administration & dosage*; D017981:Receptors, Neurotransmitter / Q000187:drug effects; D013997:Time Factors; D014191:Tranylcypromine / Q000008:administration & dosage*
D008996:Monoamine Oxidase Inhibitors; D017981:Receptors, Neurotransmitter; D014191:Tranylcypromine; D006916:5-Hydroxytryptophan; D010624:Phenelzine; D009638:Norepinephrine