title: Use of inactivated oil emulsion infectious bursal disease vaccines in breeder chickens to prevent immunosuppression in progeny chicks.
abstract: Two chicken flocks, vaccinated with different inactivated infectious bursal disease vaccines, and one unvaccinated flock provided chicks with high and low levels of and no maternally derived immunity. Following challenge at three ages with a subclinical strain of infectious bursal disease virus the chicks were assessed for bursal damage and suppression of the immune response to Newcastle disease virus. Both high and low levels of maternally derived antibody prevented immunosuppression but the lower level provided only partial protection against bursal damage.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002645:Chickens; D004655:Emulsions; D007108:Immune Tolerance; D007243:Infectious bursal disease virus / Q000276:immunology*; D009522:Newcastle disease virus / Q000276:immunology; D011201:Poultry Diseases / Q000276:immunology*; D012087:Reoviridae / Q000276:immunology*; D012088:Reoviridae Infections / Q000276:immunology / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D004655:Emulsions; D014613:Vaccines, Attenuated; D014765:Viral Vaccines