Oligoclonal IgG bands in the cerebrospinal fluid of monkeys with experimental allergic encephalomyelitis.
EAE in monkeys resulted in CSF OCB appearing 2 to 3 weeks p.i., with BP and complete Freund's adjuvant. Clinical signs appeared close to the time that the bands were first detected. The animals had serum measles antibodies, however, the titers did not change during the development of EAE and no measles antibodies were detected in the CSF.
D000818:Animals; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid; D000918:Antibody Specificity; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology*; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D007136:Immunoglobulins / Q000134:cerebrospinal fluid*; D008253:Macaca mulatta; D008459:Measles virus / Q000276:immunology; D043025:Oligoclonal Bands; D018139:Simplexvirus / Q000276:immunology
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007136:Immunoglobulins; D043025:Oligoclonal Bands