Experimental infection of cattle of different ages with infectious bovine rhinotracheitis virus (Strichen strain).
The clinical signs and pathological lesions which developed in various ages of cattle experimentally infected intranasally with the "Strichen" strain of IBR virus were similar to, but generally milder than, those of the field disease. The clinical signs were most severe 4 days after infection and had almost wholly regressed after 12 days. Serum neutralizing antibodies were detected in every animal. Virus was isolated from nasal and ocular swabs for up to 13 days and 10 days, respectively, after infection. The clinical signs and the pathological lesions were more severe in the younger animals.
D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002417:Cattle; D004198:Disease Susceptibility; D007242:Herpesvirus 1, Bovine / Q000472:pathogenicity*; D007241:Infectious Bovine Rhinotracheitis / Q000276:immunology / Q000473:pathology*; D008297:Male
D000914:Antibodies, Viral