Nephrogenic adenoma of the bladder after kidney transplantation: spontaneous improvement with azathioprine removal; surgical trauma and cytomegalovirus infection as possible etiologic factors.
We report 2 cases of nephrogenic adenoma several years after successful cadaver kidney transplantation. In 1 case the lesion had cytomegalovirus inclusions, and we observed a marked and sustained reduction in the extension of the lesion with cessation of azathioprine. Surgical trauma and cytomegalovirus infections are discussed as etiologic factors. Conservative treatment seemed appropriate.
D000236:Adenoma / Q000209:etiology*; D000328:Adult; D001379:Azathioprine; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D016030:Kidney Transplantation; D008875:Middle Aged; D013997:Time Factors; D001743:Urinary Bladder / Q000293:injuries*; D001749:Urinary Bladder Neoplasms / Q000209:etiology*
D001379:Azathioprine