title: Toxic and transforming effects of cigarette smoke condensates in fetal Syrian golden hamster lung cell cultures.
abstract: The cytotoxic and transforming effects of cigarette smoke condensates (CSCs) and benzo(a)pyrene (BaP) were compared using cultures of fetal Syrian golden hamster lung cells (FSHL). The dose-response patterns differed completely between CSCs and BaP. The amount of BaP alone failed to explain the transforming activity of CSCs.
mesh_terms: D000818:Animals; D001564:Benzo(a)pyrene; D001580:Benzopyrenes / Q000633:toxicity*; D002273:Carcinogens / Q000633:toxicity*; D002470:Cell Survival / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D002478:Cells, Cultured; D006224:Cricetinae; D005333:Fetus; D008168:Lung; D008647:Mesocricetus; D010947:Plants, Toxic; D012906:Smoke; D014026:Nicotiana
chemical_list: D001580:Benzopyrenes; D002273:Carcinogens; D012906:Smoke; D001564:Benzo(a)pyrene