title: An improved method of estimating the portal venous fraction of total hepatic blood flow from computerized radionuclide angiography.
abstract: The measurement of portal venous flow to the liver is important in the evaluation of patients for shunt surgery. A previous report described a method using slope analysis of hepatic radionuclide angiograms to generate an index of relative portal flow, which correlated well with angiographic grades of portal perfusion. The present report describes a refinement in bolus administration and a modification in technique that appear to reflect true portal venous flow more accurately. A total of 109 studies was performed, including seven normal and 80 cirrhotic patients. The method was reproducible (r = 0.998) and showed good correlation with the angiographic grades of perfusion (r = -0.906).
mesh_terms: D006801:Humans; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging; D011169:Portal Vein / Q000000981:diagnostic imaging*; D011182:Postoperative Care; D011300:Preoperative Care; D011859:Radiography; D013670:Sodium Pertechnetate Tc 99m; D013667:Technetium; D014055:Tomography, Emission-Computed / Q000379:methods*
chemical_list: D013667:Technetium; D013670:Sodium Pertechnetate Tc 99m