[Evaluation of the possibility of prognosticating the individual radiosensitivity of rats from their reaction to hypoxia and administration of ACTH].
Experiments were carried out on male rats exposed to hypoxia and treated with adrenocorticotropin. Determinations were made of the resistance to hypoxia, gas exchange, and also the concentrations of corticosterone, K, Na and the amount of leukocytes in peripheral blood. The prognostication according to these parameters allowed to predict the outcome of radiation sickness with the accuracy of 68-82%. The corticosterone parameters have proved to be the most informative ones.
D000064:Acclimatization; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D011836:Radiation Tolerance; D051381:Rats
D000324:Adrenocorticotropic Hormone
Otsenka vozmozhnosti prognozirovaniia individual'noĭ radiochuvstvitel'nosti krys po ikh reaktsii na gipoksiiu i vvedenie AKTG.