Vitamin D-mediated decrease of Ca2+-pump activity in the rat parotid gland.
In vitro activities of Ca2+-ATPase and 45Ca2+ uptake in microsomes, which were prepared from vitamin D-deficient rat parotid glands, were decreased in parallel by the oral administration of vitamin D3 as compared with those of control animals (r = 0.83). In vivo 45Ca2+ uptake in the parotid glands of vitamin D-deficient rats was also decreased by the oral administration of vitamin D3.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002762:Cholecalciferol / Q000494:pharmacology; D003600:Cytosol / Q000378:metabolism; D007473:Ion Channels / Q000378:metabolism*; D008297:Male; D008861:Microsomes / Q000378:metabolism; D010306:Parotid Gland / Q000378:metabolism*; D051381:Rats; D014808:Vitamin D Deficiency / Q000378:metabolism*
D007473:Ion Channels; D002762:Cholecalciferol; D000252:Calcium-Transporting ATPases; D002118:Calcium