Taurine antagonizes the alpha-adrenergic-positive inotropic effect of phenylephrine.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D010656:Phenylephrine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects*; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects*; D013268:Stimulation, Chemical; D013654:Taurine / Q000494:pharmacology*; D013997:Time Factors
D011941:Receptors, Adrenergic; D011942:Receptors, Adrenergic, alpha; D013654:Taurine; D010656:Phenylephrine; D011433:Propranolol