Immunocytochemical localization of ACTH1-39 in the brainstem of the rat.
The immunocytochemical distribution of ACTH1-39 (adrenocorticotropin hormone), a member of the opiocortin family of peptides, was examined in the brainstem of the rat. Immunoreactive ACTH fibers were localized in many serotonin-containing raphe nuclei and in the norepinephrine- and dopamine-containing regions throughout the brainstem. Brainstem areas involved in pain mediation contained immunoreactive ACTH fibers as well as several cranial nerve nuclei and nuclei associated with cardiovascular and respiratory functions.
D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D000818:Animals; D001933:Brain Stem / Q000032:analysis / Q000033:anatomy & histology*; D004027:Diencephalon / Q000032:analysis; D007124:Immunoenzyme Techniques; D008636:Mesencephalon / Q000032:analysis; D051381:Rats; D014018:Tissue Distribution
D000324:Adrenocorticotropic Hormone