Different bovine leukemia virus-induced tumors harbor the provirus in different chromosomes.
DNAs from 25 independent hamster X bovine somatic cell hybrids were submitted to the Southern blot analysis with probes made of unique cellular fragments adjacent to single-copy proviruses from three different bovine tumors. It appeared that these cellular sequences, and thus the respective proviruses, belonged to three different chromosomes in the three different tumors examined.
D000818:Animals; D002417:Cattle; D002874:Chromosome Mapping; D002875:Chromosomes; D006224:Cricetinae; D004262:DNA Restriction Enzymes; D005814:Genes, Viral; D006822:Hybrid Cells; D001909:Leukemia Virus, Bovine / Q000235:genetics*; D007942:Leukemia, Experimental / Q000235:genetics / Q000382:microbiology*; D009693:Nucleic Acid Hybridization; D011995:Recombination, Genetic; D012190:Retroviridae / Q000235:genetics*
D004262:DNA Restriction Enzymes