Does low pH stimulate central chemoreceptors located near the ventral medullary surface?
An in vitro preparation of the medulla oblongata of the rat was used to examine the responses to reducing pH, at constant CO2, of neurons in several identified nuclei. Neurons in an area close to the ventral surface, which is thought to be the location of pH-sensitive central respiratory chemoreceptors, did not respond differently from neurons in other medullary nuclei.
D000136:Acid-Base Equilibrium; D000818:Animals; D002628:Chemoreceptor Cells / Q000502:physiology*; D046508:Culture Techniques; D006863:Hydrogen-Ion Concentration; D008526:Medulla Oblongata / Q000502:physiology*; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology; D051381:Rats; D009435:Synaptic Transmission