Transformation of rabbit lymphocytes with T-cell leukemia virus.
Co-cultivation of rabbit lymphocytes with a human cell line carrying adult T-cell leukemia (ATL) virus (ATLV) resulted in the establishment of an ATLV-producer rabbit cell line. This cell line expressed ATL-associated antigens and reacted with antisera to the structural proteins of human T-cell leukemia virus which is identical or closely related to ATLV.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002472:Cell Transformation, Viral; D006801:Humans; D007938:Leukemia / Q000382:microbiology*; D011817:Rabbits; D012190:Retroviridae / Q000302:isolation & purification*; D013601:T-Lymphocytes / Q000382:microbiology*
D000951:Antigens, Neoplasm; D000956:Antigens, Viral