Dopamine vasodilates human cerebral artery.
In human large pial arteries, dopamine-induced relaxations appear to be mediated via dopaminergic receptors, and predominate over contractions mediated via alpha-adrenoceptors.
D000293:Adolescent; D000368:Aged; D002536:Cerebral Arteries / Q000187:drug effects*; D004298:Dopamine / Q000494:pharmacology*; D004329:Droperidol / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism; D011954:Receptors, Dopamine / Q000378:metabolism; D014664:Vasodilation / Q000187:drug effects*
D011942:Receptors, Adrenergic, alpha; D011954:Receptors, Dopamine; D011433:Propranolol; D004329:Droperidol; D004298:Dopamine; D009638:Norepinephrine; D010646:Phentolamine