title: Dual cholinergic modulation of hippocampal somatic and dendritic field potentials by the septo-hippocampal pathway.
abstract: In rats under urethane anaesthesia, brief tetanic stimulation of the medial septum produces a dual effect upon the field potentials elicited in the ammon's horn by commissural stimulation: a facilitation of the population spike recorded in the pyramidal layer and a depression of the field EPSP recorded in the apical dendrites. Both effects, which are also produced by local application of muscarinic agents, are antagonized by local administration of muscarinic antagonists.
mesh_terms: D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D002799:Cholinergic Fibers / Q000502:physiology*; D003712:Dendrites / Q000502:physiology*; D004558:Electric Stimulation; D005071:Evoked Potentials; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011976:Receptors, Muscarinic / Q000502:physiology; D012688:Septum Pellucidum / Q000502:physiology*; D009435:Synaptic Transmission
chemical_list: D011976:Receptors, Muscarinic; D000109:Acetylcholine