title: An in-vitro study of the role of sucrose and interactions between oral bacteria in possible mechanisms of dental plaque formation.
abstract: The adherence of streptococci to hydroxyapatite spheroids (HAS) depended upon the strain used, the fermentable carbon source available during bacterial growth, the number of times a clinical isolate had been subcultured on laboratory media and the pre-treatment of the HAS. Sucrose greatly stimulated the secondary colonization of Streptococcus mutans strain 3209 on HAS pre-equilibrated with this strain, but no similar effect was observed with glucose. Pre-equilibration of HAS with Streptococcus sanguis 7865 inhibited rather than enhanced subsequent colonization by Strep. mutans strain 3209 in the presence of sucrose.
mesh_terms: D000268:Adhesiveness; D003773:Dental Plaque / Q000209:etiology; D017886:Durapatite; D005947:Glucose / Q000494:pharmacology; D006801:Humans; D006882:Hydroxyapatites; D008863:Microspheres; D013295:Streptococcus mutans / Q000187:drug effects / Q000502:physiology*; D013298:Streptococcus sanguis / Q000187:drug effects / Q000502:physiology*; D013395:Sucrose / Q000494:pharmacology*
chemical_list: D006882:Hydroxyapatites; D013395:Sucrose; D017886:Durapatite; D005947:Glucose