[Decrease of the 3rd fraction of serum complement. Study in a hospital population of 13000 patients].
Patients with serum concentrations of C3 lower than 0.40 g/l among 13 000 patients in a general hospital seen over an 18 months period were studied. 95 cases were eligible for study. Diffuse and severe liver disease accounts for 50% of cases. Immunologic diseases represent little more than 10% of cases. The other common causes are severe infections and nutritional deficiencies. Besides the immunological diseases, low C3 serum concentration represents a poor prognosis factor since 55% of patients died during hospitalization.
D003176:Complement C3 / Q000172:deficiency*; D006760:Hospitalization; D006801:Humans; D007154:Immune System Diseases / Q000276:immunology; D008107:Liver Diseases / Q000276:immunology; D011183:Postoperative Complications; D018805:Sepsis / Q000276:immunology
D003176:Complement C3
Baisse de la troisième fraction du complément sérique. Etude dans une population hospitalière de 13 000 sujets.