Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system.
Immunocytochemical localization of ACTH-opiocortin perikarya was demonstrated in the medulla of colchicine-treated rat. Neuronal cell bodies and fibers containing ACTH-immunoreactivity were abundant in the caudal region of the nucleus tractus solitarius, specifically within pars commisuralis. Location of these opiocortin neurons within the nucleus tractus solitarius provides additional evidence for a role of these peptides in cardiovascular functions.
D000324:Adrenocorticotropic Hormone / Q000032:analysis*; D000818:Animals; D004285:Dogs; D004723:Endorphins / Q000502:physiology*; D006439:Hemodynamics; D006651:Histocytochemistry; D007120:Immunochemistry; D007124:Immunoenzyme Techniques; D008526:Medulla Oblongata / Q000032:analysis / Q000166:cytology*; D009474:Neurons / Q000032:analysis*; D010908:Pituitary Hormones, Anterior / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000032:analysis / Q000166:cytology*
D004723:Endorphins; D010908:Pituitary Hormones, Anterior; D000324:Adrenocorticotropic Hormone