[Change in the reaction of circulating colony forming units to ACTH in thymectomized mice].
It has been discovered that unlike animals with the intact thymus, thymectomized adult (CBA X C57B1)F1 mice did not demonstrate any reduction in the number of circulating colony-forming units (CFUs) induced by the elevated concentrations of endogenous glucocorticoids 2 weeks to 5.5 months following operation. It is assumed that the effect of glucocorticoids on CFUs is mediated by the T1 lymphocyte subpopulation.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D005260:Female; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D008297:Male; D051379:Mice; D013934:Thymectomy; D013950:Thymus Gland / Q000502:physiology*; D013997:Time Factors
D015062:11-Hydroxycorticosteroids; D000324:Adrenocorticotropic Hormone
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