[Practical value of the determination of urinary fibrin degradation products in the early management of renal transplants].
We studied daily urinary excretion of fibrin degradation products (UFDP) during the first month following renal transplantation in 31 patients using the Merskey technique. After the 48 first hours a rise of UFDP was observed in 3 circumstances: 1) acute rejection: twenty-four acute rejections were observed in twenty-two patients. The increase of UFDP was constant. It preceeded the clinical diagnosis of rejection in 63 p. 100 of the patients. It has a predictive value in all cases. 2) Severe urinary infection. In 5 patients with urologic complications UFDP rose markedly. 3) Macroscopic hematuria. In 2 patients with gross hematuria very high rates of excretion were observed.
D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000652:urine*; D006084:Graft Rejection; D006417:Hematuria / Q000652:urine; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation; D008297:Male; D011182:Postoperative Care; D012306:Risk; D014552:Urinary Tract Infections / Q000652:urine
D005338:Fibrin Fibrinogen Degradation Products; D007166:Immunosuppressive Agents
Intérêt pratique du dosage des produits de dégradation de la fibrine urinaire dans la surveillance précoce des transplantés rénaux.