[Serum activity of angiotensin converting enzyme during extracorporeal circulation in man].
Serum activity of angiotensin converting enzyme (ACE) were measured during extra-corporeal circulation in five patients undergoing aorto-coronary bypass surgery. We observed a significant decrease of serum ACE levels in the absence of pulmonary circulation, suggesting that in man the lungs were the major source of circulating ACE. An effective extra-pulmonary liberation of ACE could take place during cardiopulmonary bypass. The levels of serum ACE increased with pulmonary recirculation, but preoperative levels were not reached 24 h later.
D000368:Aged; D001026:Coronary Artery Bypass; D005112:Extracorporeal Circulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000097:blood*
D007703:Peptidyl-Dipeptidase A
Activité sérique de l'enzyme de conversion de l'angiotensine pendant la circulation extracorporelle chez l'homme.