[Free-radical disorders in the tissues of mice exposed to gamma irradiation and neutrons in vitro. The radiochemical yields].
The ESR method was used to study free-radical disturbances in tissues of mouse liver and spleen exposed in vitro to gamma-radiation and fission neutrons. It was shown that both types of radiation induced damages to basic chemical components of the cell, namely, DNA, lipids, proteins, and water. The radiochemical yields of each radical registered were obtained and RBE of neutrons were evaluated with a reference to the formation in tissues of radicals of each type. Membrane lipids were shown to be markedly injured by neutrons.
D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D005720:Gamma Rays; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D051379:Mice; D009502:Neutrons; D011854:Radiochemistry; D012062:Relative Biological Effectiveness; D013154:Spleen / Q000378:metabolism / Q000528:radiation effects*
D005609:Free Radicals
Svobodnoradikal'nye narusheniia v tkaniakh mysheĭ pri deĭstvii gamma-oblucheniia i neĭtronov in vitro. Radiatsionno-khimicheskie vykhody.