Cell membrane potential changes follow Epstein-Barr virus binding.
Upon binding to receptor-bearing target cells, viruses cause cell membrane potential changes. Epstein-Barr Virus causes a biphasic membrane potential change in receptor-bearing B lymphocytes but not receptor-negative T lymphocytes, as measured by flow cytometry or cyanine dye uptake. Membrane potential changes from EBV binding to receptor-bearing cells resemble electrical responses of other cells following ligand binding to transmembrane receptors.
D002478:Cells, Cultured; D004854:Herpesvirus 4, Human / Q000502:physiology*; D007476:Ionophores / Q000494:pharmacology; D007700:Kinetics; D008564:Membrane Potentials / Q000187:drug effects; D011991:Receptors, Virus / Q000502:physiology*
D007476:Ionophores; D011991:Receptors, Virus