Isolated profound cerebral cooling with a bi-carotid heat exchanger shunt in dogs.
Intracerebral temperatures of 15 degrees C have been achieved in 20 canine brains using a simple cannulation of the carotid arteries and interposition of a highly efficient heat exchanger. The appropriate changes in cardiovascular function and cerebral electrical activities have been documented. The extracorporeal system does not require the use of a pump oxygenator unit.
D000818:Animals; D001921:Brain / Q000502:physiology*; D002339:Carotid Arteries; D004285:Dogs; D005112:Extracorporeal Circulation; D007036:Hypothermia, Induced / Q000379:methods*