title: [Hormonal balance characteristics of patients with malignant testicular tumors in relation to the histological type of tumor].
abstract: The levels of steroid (17-HOCS, 17-CS and estrogens) and tropic (FSH, LH and ACTH) hormones were assayed and analysed versus histologic pattern and efficacy of combined therapy of tumor in 39 cases of testicular cancer. Decreased level of sex hormones matched by increased concentration of gonadotropins occurred in most patients: marked rise in FSH was observed in seminoma and that in LH--in teratoblastoma and embryonal cancer. Increased levels of 17-HOCS, estradiol, FSH and LH were observed in cases who did not respond to treatment, while lowered concentrations of FSH and LH--in cases of effective treatment. Tropic hormone and 17-HOCS concentrations were registered in cases of relapse.
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D004967:Estrogens / Q000652:urine; D005640:Follicle Stimulating Hormone / Q000097:blood; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D013724:Teratoma / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D013736:Testicular Neoplasms / Q000209:etiology / Q000378:metabolism* / Q000628:therapy
chemical_list: D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D004967:Estrogens; D006728:Hormones; D000324:Adrenocorticotropic Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Osobennosti gormonal'nogo balansa u bol'nykh zlokachestvennymi opukholiami iaichka v zavisimosti ot gistologicheskogo tipa opukholi.