title: [Cutting of insertions from DNA molecules during heteroduplex formation as a possible mechanism for maintaining genome stability].
abstract: A hypothesis has been put forward suggesting gene conversion as a mechanism of the cutting of foreign insertions (transposons, duplications) from DNA. During heteroduplex formation insertions result in one strand loops that can be attacked by nucleases specific for one strand DNA. A possible correlation is supposed to exist between the high activity of nucleases, on the one hand, and the low DNA content of genome and the absence of progressive evolution of the taxon, on the other hand.
mesh_terms: D000483:Alleles; D000818:Animals; D004247:DNA / Q000235:genetics*; D004251:DNA Transposable Elements; D004277:DNA, Single-Stranded / Q000235:genetics; D003851:Deoxyribonucleases / Q000235:genetics; D005785:Gene Conversion; D005796:Genes; D006801:Humans; D009692:Nucleic Acid Heteroduplexes / Q000235:genetics*; D011995:Recombination, Genetic
chemical_list: D004251:DNA Transposable Elements; D004277:DNA, Single-Stranded; D009692:Nucleic Acid Heteroduplexes; D004247:DNA; D003851:Deoxyribonucleases
vernacular_title: Vyrezanie vstavok iz molekul DNK pri obrazovanii geterodupleksov kak vozmozhyĭ mekhanizm podderzhaniia stabil'nosti genoma.