title: Sperm-activated channels in ascidian oocytes.
abstract: Ionic channels activated during fertilization in the ascidian oocyte membrane have been studied using the single-channel recording technique. These channels, which we have called "fertilization channels," have a single-channel conductance of about 400 pS, a reversal potential of about O mV, and an open time of 2-30 msec. The open channel probability is about 0.2 at +20 mV and increases as the membrane is depolarized. The unitary conductance is among the largest hitherto observed in biological membranes.
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D002938:Ciona intestinalis / Q000502:physiology*; D004553:Electric Conductivity; D005260:Female; D005306:Fertilization; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials; D009865:Oocytes / Q000502:physiology*; D014561:Urochordata / Q000502:physiology*
chemical_list: D007473:Ion Channels