Kinetics of viral replication and local and systemic immune responses in experimental rotavirus infection.
Rotavirus-seronegative mice were orally inoculated with murine rotavirus in order to study the kinetics of rotavirus replication and the relationship of viral replication to immunity and disease and to assess the effects of local and systemic antibodies on viral clearance and disease resolution.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D000956:Antigens, Viral / Q000032:analysis; D004261:DNA Replication; D007422:Intestines / Q000382:microbiology; D007700:Kinetics; D051379:Mice; D012401:Rotavirus / Q000235:genetics* / Q000276:immunology; D012400:Rotavirus Infections / Q000276:immunology*; D014779:Virus Replication
D000914:Antibodies, Viral; D000956:Antigens, Viral