In vitro antibacterial activity of water-soluble extract of aghalokpe.
Water-soluble extracts of the bark of aghalokpe, a big tropical tree which grows in the rainforest of Bendel State of Nigeria, showed in vitro antibacterial activity against several of the Enterobacteriaceae. The activity was more pronounced with gram-positive than the gram-negative species. The minimum inhibitory concentration (MIC) which is in the range of 3.125-50 micrograms/ml, compares well with some broad-spectrum antibiotics on the market. The extract was remarkably effective against Neisseria gonorrhoea.
D004755:Enterobacteriaceae / Q000187:drug effects*; D009344:Neisseria gonorrhoeae / Q000187:drug effects; D009549:Nigeria; D010936:Plant Extracts / Q000494:pharmacology*; D011208:Powders; D014197:Trees
D010936:Plant Extracts; D011208:Powders