Evaluation of skin vasomotor reflexes by using laser Doppler velocimetry.
We used a laser Doppler velocimeter for measurement of skin blood flow in 63 healthy control subjects and in patients with dysautonomias. We measured vasoconstrictor responses to inspiratory gasp, standing, Valsalva maneuver, and cold stimulus. An abnormal profile was defined in terms of the percentage of abnormal test results, the results of individual tests, and the alterations in the shape of the recorded response. These measurements of vasomotor function may permit the diagnosis of focal abnormalities of peripheral nerve sympathetic failure.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000686:Amyloidosis / Q000503:physiopathology; D001783:Blood Flow Velocity; D002648:Child; D003080:Cold Temperature; D003929:Diabetic Neuropathies / Q000503:physiopathology; D005260:Female; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology; D011187:Posture; D012018:Reflex / Q000502:physiology*; D012119:Respiration; D012867:Skin / Q000098:blood supply*; D013126:Spinal Nerve Roots / Q000293:injuries; D014636:Valsalva Maneuver; D014655:Vascular Resistance; D014666:Vasomotor System / Q000502:physiology*