[Effect of specific inhibitors of the enzymes of the respiratory chain and ATP-synthetase on ion transport in mitochondria induced by non-enzymic peroxide reactions].
Effect of specific inhibitors of membrane proton pumps of the respiratory chain and ATP-synthetase on ionic permeability of mitochondrial membranes induced by bivalent ferrum ions or organic hydroperoxide was studied. A conclusion is made concerning the existence of functional relations between non-specific oxidative reactions of the membranes with membrane proton pumps on the one hand and transport potassium ions in mitochondria on the other.
D025181:ATP Synthetase Complexes; D000818:Animals; D000968:Antimycin A / Q000031:analogs & derivatives / Q000494:pharmacology; D004024:Dicyclohexylcarbodiimide / Q000494:pharmacology; D007501:Iron / Q000494:pharmacology; D007700:Kinetics; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D009097:Multienzyme Complexes / Q000037:antagonists & inhibitors*; D009840:Oligomycins / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects*; D010539:Permeability; D010770:Phosphotransferases / Q000037:antagonists & inhibitors*; D051381:Rats; D012402:Rotenone / Q000494:pharmacology
D009097:Multienzyme Complexes; D009840:Oligomycins; D012402:Rotenone; C032456:antimycin; D004024:Dicyclohexylcarbodiimide; D000968:Antimycin A; D007501:Iron; D010770:Phosphotransferases; D025181:ATP Synthetase Complexes
Vliianie spetsificheskikh ingibitorov fermentov dykhatel'noĭ tsepi i ATF-sintetazy na transport ionov v mitokhondriiakh, indutsirovannyĭ nefermentativnymi perekisnymi reaktsiiami.