Modification by temperature and external calcium of the increase in spontaneous transmitter release induced by a metabolic inhibitor at the neuromuscular junction.
The increase in frequency of miniature end-plate potentials induced by sodium azide at the rat neuromuscular junction was reduced by lowering external Ca from 10(-4) M to 10(-9) M. This action of external Ca was very temperature dependent, being much more marked at lower temperatures.
D000818:Animals; D001386:Azides / Q000494:pharmacology*; D002118:Calcium / Q000502:physiology*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D019810:Sodium Azide; D009435:Synaptic Transmission / Q000187:drug effects*; D013696:Temperature
D001386:Azides; D019810:Sodium Azide; D002118:Calcium