title: Diarrhea in one to three week-old piglets associated with Clostridium perfringens type A.
abstract: Investigation on the aetiology of diarrhoea in piglets of one to three weeks of age revealed high numbers of Clostridium perfringens type A in intestinal contents of severely affected animals. Experimental infections with hysterectomy derived, colostrum deprived piglets performed in an isolator resulted in a clinical picture indistinguishable from the clinical signs observed under field conditions i.e. creamy diarrhoea, emaciation, abundant gas in the gut but usually low mortality rate. The predominant post-mortem findings were the presence of gas in the intestinal lumen and in the mucosa, superficial necrosis and villus atrophy.
mesh_terms: D000818:Animals; D002446:Celiac Disease / Q000209:etiology / Q000382:microbiology / Q000662:veterinary; D003015:Clostridium Infections / Q000382:microbiology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification; D003967:Diarrhea / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D005243:Feces / Q000382:microbiology; D005260:Female; D013552:Swine; D013553:Swine Diseases / Q000209:etiology* / Q000382:microbiology