Unusual type of mitochondrial DNA in mice lacking a maternally transmitted antigen.
Mice that lack a maternally transmitted antigen (Mta) on the cell surface share a distinctive type of mitochondrial DNA. This is evident from restriction analyses of mitochondrial DNAs from 25 strains of mice whose antigenic state is known. One hundred sixty-eight cleavage sites have been mapped in the mitochondrial DNA of Mta- mice. Detailed maps for the 8 other types of mitochondrial DNA detected in the survey have also been prepared. The Mta- mice are estimated to differ from those expressing the antigen by 108 to 141 base substitutions at widely scattered points in the mitochondrial genome.
D000818:Animals; D000954:Antigens, Surface / Q000235:genetics*; D002462:Cell Membrane / Q000276:immunology; D004262:DNA Restriction Enzymes; D004272:DNA, Mitochondrial / Q000235:genetics*; D051379:Mice / Q000235:genetics* / Q000276:immunology
D000954:Antigens, Surface; D004272:DNA, Mitochondrial; D004262:DNA Restriction Enzymes