T-cell hybrids. IV. One of parental cell lines is dominant in determining membrane characteristics of hybrid cells.
Membrane characteristics of parental thymic lymphoma cells (BW5147, EL-4R) and their hybrids (BH2) derived by PEG-promoted cell fusion were compared. Isoelectric focusing of the cell populations, titration of membrane proton binding groups and quantitative examination of cell-substrate adhesiveness indicated that the BW5147 cells behaved as dominant in determining cell membrane characteristics of the BH2 hybrids.
D000818:Animals; D002448:Cell Adhesion; D002462:Cell Membrane / Q000502:physiology; D006822:Hybrid Cells / Q000502:physiology / Q000648:ultrastructure*; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing; D051379:Mice; D011522:Protons; D013601:T-Lymphocytes / Q000502:physiology / Q000648:ultrastructure*
D011522:Protons