Transient tension development induced by silver ion in Ca2+ -channel blocked skeletal muscle fibers.
Ag+ produced two different types of transient tension development in single frog toe muscle fibers in which the Ca2+ channel had been blocked by pretreatment with 2mM Co2+. These contractions were never observed in detubulated fibers, indicating that the Ag+ -induced contraction is produced through Ca2+ channels located on the T-tubular membrane.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003035:Cobalt / Q000494:pharmacology; D004558:Electric Stimulation; D007473:Ion Channels / Q000187:drug effects*; D009119:Muscle Contraction / Q000187:drug effects*; D011892:Rana catesbeiana; D012834:Silver / Q000494:pharmacology*
D007473:Ion Channels; D003035:Cobalt; D012834:Silver; D002118:Calcium