Specious hybridization between herpes simplex virus DNA and human cellular DNA.
Apparent hybridization between human cellular DNA and herpes simplex virus DNA was blocked by the presence of guanine-rich ribo- and deoxyribonucleic acid polymers. The data indicate that the apparent hybridization may very well be artifactual and not represent long stretches of authentic base sequence homology.
D001483:Base Sequence; D004247:DNA / Q000235:genetics*; D004269:DNA, Bacterial / Q000494:pharmacology; D004274:DNA, Recombinant; D004279:DNA, Viral / Q000235:genetics*; D004338:Drug Combinations; D006801:Humans; D008837:Micrococcus; D009693:Nucleic Acid Hybridization / Q000187:drug effects; D011068:Poly G / Q000494:pharmacology; D011072:Poly U / Q000494:pharmacology; D018139:Simplexvirus / Q000187:drug effects / Q000235:genetics*
D004269:DNA, Bacterial; D004274:DNA, Recombinant; D004279:DNA, Viral; D004338:Drug Combinations; D011068:Poly G; C023795:poly(U-G); D011072:Poly U; D004247:DNA