Virus-like particles in leukaemia.
Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D002675:Child, Preschool; D003593:Cytoplasm / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007945:Leukemia, Lymphoid / Q000382:microbiology* / Q000473:pathology