title: [Hepatopathies associated with chronic carriage of HBs antigen in black African immigrants in France].
abstract: The authors report two studies : 1) Retrospective : study of liver biopsies in 44 Africans : 22 were HBs Ag positive and 22 HBs Ag negative ; 10 of the HBs Ag positive subjects were found to have chronic persistent hepatitis (CPH), 4 chronic active hepatitis (CAH) and 3 cirrhosis ; 2 of the HBs Ag negative subjects were found to have CPH and 3 CAH ; as far a biological findings are concerned, only the CAH and cirrhosis groups differed from the control group, with higher prothrombin times, transaminase levels and gammaglobulin levels. 2) Prospective : study of the incidence of HBs Ag carriage in 168 Africans ; 17.8 % of them were found to be carriers ; no correlation was found between HBs Ag carriage and S. haematobium schistosomiasis or hemoglobinopathies.
mesh_terms: D000328:Adult; D000354:Africa, Western / Q000208:ethnology; D002353:Carrier State; D002908:Chronic Disease; D005602:France; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000276:immunology* / Q000473:pathology; D012189:Retrospective Studies
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Les hépatopathies associées au portage chronique de l'antigène hbs chez les noirs africains immigrés en France.