What has the baboon to offer as a model of experimental ischemia?
The greatest advantage of the baboon model is the phylogenetic closeness of the animal to man which may be of considerable importance when dealing with receptor-related events and with drug-specific therapy. The major disadvantage is the difficulty of dealing with awake baboons and the absence of any adequate model for coronary artery spasm.
D000818:Animals; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D000242:Cyclic AMP / Q000032:analysis; D004195:Disease Models, Animal; D006321:Heart / Q000033:anatomy & histology; D010215:Papio / Q000502:physiology; D014693:Ventricular Fibrillation / Q000503:physiopathology
D000242:Cyclic AMP