Role of recent vaccination in production of false-positive coronavirus antibody titers in cats.
Statistical support was obtained for an association between recent vaccination of cats and the presence of elevated background (i.e., anti-cell culture) reactivity in certain of their sera, as detected with a kinetics-based enzyme-linked immunosorbent assay for coronavirus antibodies, implicating routine vaccination as a potential cause of false-positive antibody test results.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002371:Cat Diseases / Q000276:immunology*; D002415:Cats; D003332:Coronaviridae / Q000276:immunology*; D003333:Coronaviridae Infections / Q000276:immunology / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D008297:Male; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary*
D000914:Antibodies, Viral