title: A clinical approach to non-A, non-B hepatitis.
abstract: Non-A, non-B agents are currently the major cause of posttransfusion hepatitis and a major cause of chronic active hepatitis in the United States. Recent investigations suggest the clinical entity of non-A, non-B hepatitis results from infection with one of at least two distinct viruses. These viruses produce hepatitis with different incubation periods, induce different histopathologic characteristics, and have different antigenic determinants. The clinical and virologic aspects of non-A, non-B hepatitis are reviewed.
mesh_terms: D000328:Adult; D000937:Antigen-Antibody Reactions; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications; D004267:DNA Viruses / Q000276:immunology; D006386:Hemagglutination Tests; D006512:Hepatitis B Core Antigens / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000276:immunology; D006526:Hepatitis C / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D012328:RNA Viruses / Q000276:immunology; D011863:Radioimmunoassay; D013997:Time Factors; D065227:Transfusion Reaction; D014777:Virus Diseases / Q000150:complications
chemical_list: D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens