Autoradiographic localization of prazosin binding sites in rat kidney.
[3H]Prazosin is a selective ligand for alpha 1-adrenoceptors. Using an in vitro autoradiographic technique specific binding of [3H]prazosin has been demonstrated, mainly to the renal cortex of the rat. These results provide further evidence that, in the rat, there is a high density of alpha 1-adrenoceptors within the renal cortex.
D000818:Animals; D001345:Autoradiography; D002540:Cerebral Cortex / Q000378:metabolism; D007672:Kidney Cortex / Q000378:metabolism*; D008297:Male; D008526:Medulla Oblongata / Q000378:metabolism; D011224:Prazosin / Q000378:metabolism*; D011799:Quinazolines / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011942:Receptors, Adrenergic, alpha / Q000378:metabolism*
D011799:Quinazolines; D011942:Receptors, Adrenergic, alpha; D011224:Prazosin