Susceptibility to mecillinam and other antibiotics and serogroups of enterotoxigenic Escherichia coli from children in Addis Ababa.
The in-vitro susceptibility of 64 strains of enterotoxigenic Escherichia coli (ETEC) was determined for eight antimicrobial agents. The strains were of 27 different O-serogroups of which 078 was the most common. All strains were susceptible to mecillinam, cefoxitin, gentamicin, and trimethoprim-sulphamethoxazole. Two strains were resistant to ampicillin, 15 to doxycycline, 5 to cephalothin, and 13 to chloramphenicol. No difference was found in the antibiotic susceptibility of ETEC strains producing only heat-labile enterotoxin compared with those producing both heat-labile and heat-stable enterotoxin.
D000560:Amdinocillin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D004768:Enterotoxins / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D005002:Ethiopia; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D010397:Penicillanic Acid / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D004768:Enterotoxins; D010397:Penicillanic Acid; D000560:Amdinocillin