title: A polymorphic DNA marker genetically linked to Huntington's disease.
abstract: Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.
mesh_terms: D002874:Chromosome Mapping; D002905:Chromosomes, Human, 4-5; D003001:Cloning, Molecular; D004262:DNA Restriction Enzymes; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D010375:Pedigree; D011110:Polymorphism, Genetic
chemical_list: D004262:DNA Restriction Enzymes