title: [Hepatitis and hepatocellular carcinoma].
abstract: Most of Hepatocellular carcinoma (HCC) in Japan are accompanied with liver cirrhosis (LC) or fibrosis and histopathological investigation based on materials disclosed the gradual transition from hepatitis to LC and then HCC. In recent years, it was clarified that, using sensitive assay methods for Hepatitis B Virus (HBV) markers, most of sera from HCC patients had HBV markers, indicating that HBV might play an important role in the progress and/or establishment of chronic liver diseases and HCC. In this paper, our experiences of the transition from type B hepatitis to HCC confirmed by serial liver biopsies were presented mainly, then I explained about the clinicopathological studies of NonA NonB hepatitis, of which virus markers were not yet found, in relation to HCC.
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000276:immunology / Q000473:pathology*; D005260:Female; D006505:Hepatitis / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D006509:Hepatitis B / Q000473:pathology; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006526:Hepatitis C / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged
chemical_list: D006514:Hepatitis B Surface Antigens