title: Adenoma of the rectum with multiple foci of signet-ring cell carcinoma. Report of a case.
abstract: A case with multiple foci of signet-ring cell carcinoma in an adenoma of the rectum is presented. Four foci of the signet-ring cell carcinoma and four foci of the common type of adenocarcinoma were found independently in a large polypoid tumor. An originating point of one of the signet-ring cell cancer foci was shown by an extensive serial sectioning study.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D000368:Aged; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012004:Rectal Neoplasms / Q000473:pathology*