[Phagocytosis of Candida albicans L-45 in vitro and evaluation of the changes in the intensity of the reaction to 5'-nucleotidase of neutrophils in men chronically exposed to carbon disulfide].
The phagocytosis capability of the Candida albicans in vitro by neutrophils of 30 men chronically CS2 exposed has been tested, along with the cytoenzymatic reaction to 5 nucleotidase in those neutrophils. The control group consisted of 10 voluntary blood donors. Considerable statistically significant decrease in all the parameters of the pathogenic fungus phagocytosis test has been found. The rate of cells with positive reaction to 5 nucleotidase did not differ significantly from correct values. It may be expected that in the CS2 exposed people neutrophils functioning gets impaired due to direct and indirect effects of carbon disulphide.
D015720:5'-Nucleotidase; D000328:Adult; D000393:Air Pollutants / Q000633:toxicity*; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D002176:Candida albicans / Q000276:immunology*; D002246:Carbon Disulfide / Q000633:toxicity*; D002462:Cell Membrane / Q000201:enzymology; D002478:Cells, Cultured; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology* / Q000648:ultrastructure; D009708:Nucleotidases / Q000097:blood; D010587:Phagocytosis; D013997:Time Factors
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D009708:Nucleotidases; D015720:5'-Nucleotidase; D002246:Carbon Disulfide
Ocena fagocytozy in vitro grzyba Candida albicans L-45 oraz ocena zmian intensywnosci odczynu na 5'nukleotydaze w neutrofilach u mezczyzn przewlekle narazonych na działanie dwusiarczku wegla.