[Experimental infection of mice by Salmonella typhi inoculated orally: influence of immunosuppressive therapy].
Various immunosuppressive treatments were used in order to induce a Salmonella typhi infection in mouse by oral route. Neither low protein diets nor administration of mucin, iron, streptomycin or silica could modify animal's sensitiveness, but, cyclophosphamide injections enhanced lethal effect of bacteria, while silica increased the number of bacteria in the blood and the spleen.
D000284:Administration, Oral; D000818:Animals; D005260:Female; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D007501:Iron / Q000494:pharmacology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009077:Mucins / Q000494:pharmacology; D012822:Silicon Dioxide / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D014435:Typhoid Fever / Q000276:immunology*
D007166:Immunosuppressive Agents; D009077:Mucins; D012822:Silicon Dioxide; D007501:Iron; D013307:Streptomycin
Infection expérimentale de la Souris par Salmonella typhi inoculée par voie buccale: influence des traitements immunodépresseurs.