[Ultrastructural characteristics of a focus of recurrent infection in genital herpes patients (clinical and electron microscopy studies)].
In patients with recurrent genital herpes in the active stage of herpetic infection, herpes simplex virus (HSV) is located both extra- and intracellularly in keratinocytes of the pricky and glandular layers of the epidermis as well as in macrophages and neutrophilic leukocytes. The observed incompleted phagocytosis of HSV by macrophages may be one of the causes of insufficient local resistance to the virus.
D000328:Adult; D004817:Epidermis / Q000382:microbiology / Q000648:ultrastructure; D005260:Female; D005490:Focal Infection / Q000382:microbiology / Q000473:pathology*; D006558:Herpes Genitalis / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000382:microbiology / Q000648:ultrastructure; D008264:Macrophages / Q000382:microbiology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012008:Recurrence; D018139:Simplexvirus / Q000648:ultrastructure; D014771:Virion / Q000648:ultrastructure
Ul'trastrukturnaia kharakteristika ochaga retsidiviruiushcheĭ infektsii u bol'nykh genital'nym gerpesom (klinicheskoe i élektronno-mikroskopicheskoe issledovanie).