Analysis of sodium current fluctuations in the cut-open squid giant axon.
Patch pipettes were used to record the current arising from small populations of sodium channels in voltage-clamped cut-open squid axons. The current fluctuations associated with the time-variant sodium conductance were analyzed with nonstationary statistical techniques in order to obtain an estimate for the conductance of a single sodium channel. The results presented support the notion that the open sodium channel in the squid axon has only one value of conductance, 3.5 pS.
D000818:Animals; D001369:Axons / Q000378:metabolism*; D049832:Decapodiformes / Q000378:metabolism*; D004594:Electrophysiology; D007473:Ion Channels / Q000378:metabolism*; D051381:Rats; D012964:Sodium / Q000378:metabolism*
D007473:Ion Channels; D012964:Sodium