Derivation of neutralizing monoclonal antibodies against rotavirus.
Monoclonal antibodies were derived against the SA11 simian, NIC bovine, and Wa human rotavirus strains and characterized by enzyme-linked immunosorbent assay, plaque neutralization, and hemagglutination inhibition. Several strain SA11-specific antibodies were found to have neutralizing and hemagglutination-inhibiting capacity.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000914:Antibodies, Viral / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006385:Hemagglutination Inhibition Tests; D006825:Hybridomas / Q000276:immunology; D009500:Neutralization Tests; D012401:Rotavirus / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral