title: Immunohistochemical demonstration of human papilloma virus (HPV) antigens in oral squamous cell lesions.
abstract: Six oral squamous cell tumours classified as focal epithelial hyperplasia (FEH), Condyloma acuminatum (CA) and squamous cell papilloma (SQP) were subjected to indirect immunoperoxidase staining with anti-human papillomavirus (anti-HPV) antiserum to demonstrate the possible presence of HPV antigens in these lesions. The results are discussed in the light of the observations on HPV-lesions elsewhere in the body (in uterine cervix), and a suggestion is made to adopt the name condyloma for all those tumours where HPV aetiology can be established by ultrastructural or immunohistochemical means.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000032:analysis*; D002648:Child; D003218:Condylomata Acuminata / Q000276:immunology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000276:immunology; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000473:pathology; D009062:Mouth Neoplasms / Q000276:immunology*; D010212:Papilloma / Q000276:immunology; D027383:Papillomaviridae / Q000276:immunology*
chemical_list: D000956:Antigens, Viral