[Relation between hormonal and hemodynamics indices during emotional stress in healthy individuals and in hypertensive patients].
Relationships between hormonal and hemodynamic parameters were examined during emotional stress in normal subjects and patients with essential hypertension. Plasma renin activity, aldosterone, cortisol concentration in the plasma and ACTH level, urinary catecholamine excretion were assayed, and arterial blood pressure, heart rate, ECG were recorded in 29 normal controls and 39 hypertensive patients before and after exposure to emotional stress. The findings were processed using the cluster technique of multivariable statistical analysis. Emotional stress was shown to produce more correlations in the system of hormonal balance compared to resting conditions, the interhormonal correlations being more pronounced in hypertensive patients as compared to normal controls. Stress-induced hypertensive response was shown to be achieved via different means: predominantly sympathoadrenal activation in normal subjects and the activation of renin-angiotensin-aldosterone system in hypertensive patients.
D000302:Adrenal Cortex / Q000503:physiopathology; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000450:Aldosterone / Q000097:blood; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System; D013315:Stress, Psychological / Q000150:complications* / Q000503:physiopathology*
D000450:Aldosterone; D000324:Adrenocorticotropic Hormone; D012083:Renin; D006854:Hydrocortisone
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