title: Behavioral and physiological effects of ethanol in high-risk and control children: a pilot study.
abstract: Blood and breath acetaldehyde levels were measured following ethanol ingestion (0.5 ml/kg) in 11 boys familially at risk for alcoholism and 11 age-matched controls. No significant differences were found between groups for acetaldehyde, objective, or subjective measures of intoxication. Previous reports of acetaldehyde as a marker of risk for alcoholism were not confirmed. Baseline behavioral state predicted response to alcohol. Children tended to have a subjective response in a direction opposite from the baseline mood state.
mesh_terms: D000079:Acetaldehyde / Q000097:blood; D000293:Adolescent; D000339:Affect / Q000187:drug effects; D000428:Alcohol Drinking; D000437:Alcoholism / Q000097:blood / Q000235:genetics*; D002648:Child; D002653:Child Behavior Disorders / Q000097:blood*; D004723:Endorphins / Q000097:blood; D000431:Ethanol / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D012306:Risk; D001615:beta-Endorphin
chemical_list: D004723:Endorphins; D000431:Ethanol; D001615:beta-Endorphin; D000079:Acetaldehyde