[Study of the course of development in 84 non-insulin-dependent diabetics over a 5-to-10-year period. Their therapeutic outcome].
The clinical, biological and therapeutic course of non-insulin-dependent (type II) diabetes mellitus was studied in 84 patients followed up for five to ten years. Three-quarters of these patients, who had had diabetes mellitus for approximately ten years in most cases, were well controlled although they remained overweight, presumably as a result of poor compliance with nutritional prescriptions. Disturbances in lipids were only incompletely corrected in 60% of patients. Arterial hypertension persisted in 15%. Oral therapy remained effective in 70% of patients. Among the 30% of patients given insulin, 13% were so treated because of renal failure. Notwithstanding the satisfactory control of diabetes mellitus, probably as a result of the persistence of other risk factors, micro and macroangiopathic complications occurred or worsened during the follow up period.
D000328:Adult; D000368:Aged; D001786:Blood Glucose; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000209:etiology; D003928:Diabetic Nephropathies / Q000209:etiology; D003929:Diabetic Neuropathies / Q000209:etiology; D003927:Diet, Diabetic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D014527:Uric Acid
Etude évolutive de quatre-vingt-quatre diabétiques non insulino-dépendants sur une période de cinq à dix ans. Leur devenir thérapeutique.