title: Autoradiographic localization of [3H]choline uptake in the brain of Drosophila melanogaster.
abstract: We describe the localization of sites for choline uptake in the brain of Drosophila melanogaster by the technique of autoradiography of diffusible substances. After systemic injection of [3H]choline, heavy labelling is found in certain regions of the ventral mid-brain, the antennal mechanosensory system including certain commissures, the olfactory lobes and the antennal glomerular tract. This accumulation of label is sensitive to hemicholinium-3 and can be suppressed by incubation at 0 degrees C. It is proposed that acetylcholine is a major neurotransmitter of the antennal mechanosensory and chemosensory systems of Drosophila.
mesh_terms: D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D002794:Choline / Q000378:metabolism*; D002799:Cholinergic Fibers / Q000502:physiology; D004331:Drosophila melanogaster / Q000378:metabolism*; D005724:Ganglia / Q000378:metabolism*; D009799:Ocular Physiological Phenomena; D009435:Synaptic Transmission; D014796:Visual Perception / Q000502:physiology
chemical_list: D002794:Choline; D000109:Acetylcholine