The effects of parathyroid hormone, calcitonin, and vitamin D metabolites on calcium transport in the secretory rat enamel organ.
The effects of parathyroid hormone (PTH), calcitonin (CT), 1,25(OH)2D3, and 24,25(OH)2D3 on calcium transport through the secretory stage enamel organ were studied on developing rat molars in vitro. 24,25(OH)2D3 increased 45Ca uptake by the explants. 24,25(OH)2D3 plus PTH further enhanced 45Ca uptake and resulted in an increase in net calcium uptake by the developing enamel.
D000818:Animals; D002116:Calcitonin / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D002762:Cholecalciferol / Q000494:pharmacology; D004658:Enamel Organ / Q000378:metabolism*; D008963:Molar; D010281:Parathyroid Hormone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D014083:Tooth Germ / Q000378:metabolism*; D014807:Vitamin D / Q000378:metabolism / Q000494:pharmacology*
D010281:Parathyroid Hormone; D014807:Vitamin D; D002762:Cholecalciferol; D002116:Calcitonin; D002118:Calcium