title: [Evaluation of testicular biopsy in subfertile men based on semithin-section preparations].
abstract: The semithin-section technique represents an advanced light-microscopic method which furthers the investigation of development in spermatogenesis and the associated disturbances in subfertile men. This is demonstrated using examples in which the histological findings from paraffin-section preparations have been compared to the semithin-sections preparations from the same patient. In contrast to the paraffin-section technique, the various appearances of the spermatid malformations in patients with oligozoospermia can be assessed with the semithin-section technique. The therapeutic prospects of success depend on the type and extent of such malformations. In addition, semithin-section preparations from a testicular biopsy in subfertile patients can be used to identify tumor cells. For these reasons, because of the implications of a grave diagnosis and the resulting therapeutic consequences, the semithin-section technique is recommended as a routine method in the assessment of testicular biopsies.
mesh_terms: D000328:Adult; D001706:Biopsy; D003584:Cytological Techniques; D006801:Humans; D007248:Infertility, Male / Q000473:pathology*; D008297:Male; D009845:Oligospermia / Q000473:pathology; D012671:Seminiferous Tubules / Q000473:pathology; D013091:Spermatogenesis; D013737:Testis / Q000473:pathology*
vernacular_title: Zur Beurteilung der Hodenbiopsie bei subfertilen Männern anhand von Semidünnschnitt-Präparaten.