title: Single channel studies on inactivation of calcium currents.
abstract: Inactivation of calcium channels has been attributed to a direct reaction of calcium ions entering the cell with the calcium channel. For a single channel this hypothesis predicts a correlation between the amount of calcium entering during an opening or a burst of openings and the subsequent closed times. No such correlation was found, and the possibility that, upon entry, calcium ions produce inactivation is excluded.
mesh_terms: D002118:Calcium / Q000378:metabolism*; D004594:Electrophysiology; D006372:Helix, Snails; D007473:Ion Channels / Q000502:physiology*; D008564:Membrane Potentials
chemical_list: D007473:Ion Channels; D002118:Calcium