Anaerobic cultures of Salmonella typhimurium do not exhibit inducible proteolytic function of the recA gene and recBC function.
In a strict anaerobic environment, lack of expression of bacterial recBC function and recA regulatory functions for the SOS repair system is demonstrated by the use of the carcinogenesis-mutagenesis assay and Salmonella phage P22 mutants requiring these host functions for replication. Therefore, we suggest that error-prone repair (SOS repair) is confined to aerobic environments in facultative anaerobes.
D000332:Aerobiosis; D000693:Anaerobiosis; D004260:DNA Repair; D029968:Escherichia coli Proteins; D043211:Exodeoxyribonuclease V; D005090:Exodeoxyribonucleases / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D009154:Mutation; D010447:Peptide Hydrolases / Q000235:genetics*; D011938:Rec A Recombinases / Q000235:genetics*; D012486:Salmonella typhimurium / Q000201:enzymology / Q000235:genetics*; D013045:Species Specificity; D014161:Transduction, Genetic
D029968:Escherichia coli Proteins; D011938:Rec A Recombinases; D005090:Exodeoxyribonucleases; D043211:Exodeoxyribonuclease V; C468322:exodeoxyribonuclease V, E coli; D010447:Peptide Hydrolases