title: Distinct populations of class II molecules identified by monoclonal antibodies.
abstract: Binding inhibition and sequential immunoadsorption studies with two rat monoclonal antibodies have been used to demonstrate the existence of distinct populations (isotypes) of HLA-DR like (class II) molecules in human B lymphoma cell lysates. The structures of the molecules isolated by these two reagents have been compared by peptide 'mapping' and appear to be closely similar.
mesh_terms: D000911:Antibodies, Monoclonal; D002051:Burkitt Lymphoma / Q000032:analysis; D002460:Cell Line; D004591:Electrophoresis, Polyacrylamide Gel; D000949:Histocompatibility Antigens Class II; D006801:Humans; D007163:Immunosorbent Techniques; D010455:Peptides / Q000032:analysis
chemical_list: D000911:Antibodies, Monoclonal; D000949:Histocompatibility Antigens Class II; D010455:Peptides