[Effect of monoamines on luliberin levels in various parts of the hypothalamus of the male rat].
The effect of the monoamines--noradrenaline, dopamine and serotonin, injected into the third cerebral ventricle, on luliberin (LH-RH) content in the individual hypothalamic regions and the blood luteinizing hormone (LH) level, was studied in male rats. A reduced LH-RH level in the median eminence area and enhanced blood LH concentration were seen after noradrenaline injection. The number of cases where LH-RH level could be detectable in the blood, augmented following dopamine injection. The results obtained evidence that noradrenaline and dopamine participate in regulation of LH-RH synthesis and secretion and therefore in regulating the hypophyseal gonadotropic function.
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000378:metabolism; D004298:Dopamine / Q000008:administration & dosage*; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006727:Hormone Antagonists; D007031:Hypothalamus / Q000378:metabolism*; D007276:Injections, Intraventricular; D008297:Male; D008473:Median Eminence / Q000378:metabolism; D009638:Norepinephrine / Q000008:administration & dosage*; D011301:Preoptic Area / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000008:administration & dosage*
D006727:Hormone Antagonists; D012701:Serotonin; D007987:Gonadotropin-Releasing Hormone; D004298:Dopamine; D009638:Norepinephrine
Vliianie monoaminov na soderzhanie liuliberina v razlichnykh otselakh gipotalamusa samtsov krys.