[Morphological effects of microinjections of Lewis rat serum into nerves of Lewis rats].
Recent reports have shown that intraneural injections of sera from patients with Guillain-Barré syndrome have demyelinating effects on rat peripheral nerve. Some authors have proposed that this could merely result from immune phenomena due to species differences. In this study we injected normal human sera and sera from normal Lewis rats into nerves of Lewis rats. We consider that the small lesions observed were due more to the injection procedure itself than to effects of the sera.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D001769:Blood / Q000276:immunology*; D003711:Demyelinating Diseases / Q000473:pathology; D008845:Microinjections / Q000009:adverse effects; D010525:Peripheral Nerves / Q000473:pathology* / Q000648:ultrastructure; D051381:Rats; D011917:Rats, Inbred Lew; D012584:Sciatic Nerve / Q000473:pathology
Effets morphologiques de microinjections de sérum de rat Lewis dans le nerf de rat Lewis.