title: Histopathological diagnosis of hydatidiform mole.
abstract: Two microscopical methods are described which are useful for the identification of hydatidiform molar trophoblast. The first is an application of Nomarski's differential interference contrast microscopy which allows whole-mounted villi to be studied by optical sectioning. The second is an application of indirect immunofluorescence microscopy using a specific antiserum directed against the endothelial cell structural protein-known as vimentin.
mesh_terms: D005260:Female; D005455:Fluorescent Antibody Technique; D006652:Histological Techniques; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000473:pathology*; D008857:Microscopy, Interference; D011247:Pregnancy; D013997:Time Factors; D014327:Trophoblasts / Q000473:pathology; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology*