Plaques and platelets. The vascular surgeon's challenge and dilemma.
Vascular surgeons have not paid enough attention to all of the host factors responsible for the pathogenesis of atherosclerosis. With a clearer understanding of the role of platelets and endothelial cells, improved results and better long-term palliation can be realized by combining newer pharmacologic approaches with well-established surgical procedures. Prostaglandin chemistry research may provide promising therapeutic adjuncts to current techniques for managing atherosclerosis.
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology*; D001792:Blood Platelets / Q000187:drug effects / Q000502:physiology*; D011464:Epoprostenol / Q000502:physiology; D006801:Humans; D010974:Platelet Aggregation; D012306:Risk; D013927:Thrombosis / Q000209:etiology; D013928:Thromboxane A2 / Q000502:physiology
D013928:Thromboxane A2; D011464:Epoprostenol