Chronic bullous dermatosis of childhood.
Chronic blistering dermatosis of childhood (CBDC) in a 1-year-old black girl responded to the administration of sulfapyridine. CBDC is a rare blistering skin disease characterized by the presence of tense bullae and the linear deposition of IgA at the dermal-epidermal junction of lesional and perilesional skin. The disease may resemble bullous impetigo, bullous erythema multiforme, dermatitis herpetiformis, or pemphigus. The treatment involves the use of either dapsone or sulfapyridine.
D002908:Chronic Disease; D003874:Dermatitis Herpetiformis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007223:Infant; D010392:Pemphigus / Q000175:diagnosis; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D013427:Sulfapyridine / Q000627:therapeutic use
D007070:Immunoglobulin A; D013427:Sulfapyridine