[Correlation of spleen colony formation and changes in spleen weight during its recovery in irradiated mice].
In experiments on (CBA X C57Bl)F1 and BALB/c mice it was shown that with the spleen mass increasing, due to exo- and endorepopulation, during the postirradiation regeneration of the spleen, the number of splenic colonies also increases to a certain level. When the spleen mass reaches 1/3 of that lost after irradiation the number of discrete colonies decreases. When the spleen mass is restored to about 1/2 solitary colonies do not form at all. The spleen mass can considerably exceed the normal level in conditions of intensive repopulation.
D000818:Animals; D016026:Bone Marrow Transplantation; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009929:Organ Size / Q000528:radiation effects; D013154:Spleen / Q000528:radiation effects*
Sootnoshenie selezenochnogo kolonieobrazovaniia i izmeneniia massy selezenki pri ee vosstanovlenii u obluchennykh mysheĭ.