title: [Anomalies of phospho-calcium metabolism during antiepileptic treatment].
abstract: It is known that, particularly in Nordic States, many patients undergoing antiepileptic therapy with Phenobarbital and Phentoin present disorders of the phospho-calcium metabolism, both clinical and biochemical. For what concerns the mediterranean area, few are the papers written concerning this subject in these last years. In this paper we attempt to provide a "case study" contribution (100 cases) to enable us to study the above-mentioned alteration focusing on an area half way between Central and Southern Europe. The Authors discuss the possible mechanism implicated in this affection.
mesh_terms: D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D000927:Anticonvulsants / Q000009:adverse effects*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004872:Ergocalciferols / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D010634:Phenobarbital / Q000008:administration & dosage / Q000009:adverse effects; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects; D010758:Phosphorus / Q000097:blood / Q000378:metabolism*; D012279:Rickets / Q000139:chemically induced* / Q000517:prevention & control
chemical_list: D000927:Anticonvulsants; D004872:Ergocalciferols; D010758:Phosphorus; D010672:Phenytoin; D000469:Alkaline Phosphatase; D002118:Calcium; D010634:Phenobarbital
vernacular_title: Anomalie del metabolismo fosfo-calcico nel corso di trattamento antiepilettico.