title: Pharmacological properties of oxotremorine and its analogs.
abstract: The mechanism of action of oxotremorine is reviewed. A number of analogs of oxotremorine, including agonists, partial agonists and antagonists, are described. Many of these are potent and highly specific in their central actions. The possible basis for this specificity is outlined.
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002490:Central Nervous System / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D007082:Ileum / Q000378:metabolism; D010095:Oxotremorine / Q000031:analogs & derivatives / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D010525:Peripheral Nerves / Q000187:drug effects; D011976:Receptors, Muscarinic / Q000187:drug effects / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D011976:Receptors, Muscarinic; D010095:Oxotremorine; D000109:Acetylcholine