title: Distribution of C cells in monkey thyroid glands as studied by the immunoperoxidase method using anti-calcitonin and anti-C-thyroglobulin antisera.
abstract: The distribution of C cells in the thyroid glands of eight young adult monkeys (4 Macaca fuscata and 4 Macaca irus) was investigated by complete serial sections utilizing the immunoperoxidase method with anti-human calcitonin and anti-dog C-thyroglobulin antisera. The secretory granules of monkey C cells were strongly immunoreactive to both antisera. A markedly uneven distribution of C cells was found. The C cells were distributed in a small area restricted to the dorsomedial portion of the lobe along the longitudinal axis below the parathyroid IV, while the remaining larger portions were devoid of C cells. In the areas where the C cells were concentrated, the cells were scattered, surrounding a large portion or even the whole of the epithelium lining follicles and often forming multiple clusters among the follicles. In these places the C cells exceeded the number of follicular cells.
mesh_terms: D000818:Animals; D002116:Calcitonin / Q000378:metabolism; D005260:Female; D007124:Immunoenzyme Techniques; D008251:Macaca / Q000033:anatomy & histology*; D008297:Male; D010280:Parathyroid Glands / Q000166:cytology; D013954:Thyroglobulin / Q000378:metabolism; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism
chemical_list: D002116:Calcitonin; D013954:Thyroglobulin