Peliosis of the spleen. Report of a case associated with chronic myelomonocytic leukemia, presenting with spontaneous splenic rupture.
A 62-year-old man had chronic myelomonocytic leukemia (untreated) for a period of 8 years. He developed a sudden, spontaneous rupture of the spleen and a splenectomy was performed. Grossly and microscopically the spleen showed peliosis. The blood-filled cavities were similar to the pseudosinuses described in the spleen of hairy-cell leukemia. The lesion common to these disorders apparently is a progressive disappearance of lining cells and of ring fibers.
D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011693:Purpura / Q000473:pathology*; D012422:Rupture, Spontaneous; D013154:Spleen / Q000473:pathology; D013158:Splenic Diseases / Q000473:pathology*; D013161:Splenic Rupture / Q000209:etiology*