HLA-DR phenotypes and blood levels of T cell subsets.
Blood mononuclear cell and T cell subsets values were analyzed in 53 Sicilian individuals according to HLA-DR phenotypes. The results demonstrate that DR1-positive subjects show a significant increase of blood T cell subsets whereas DR3-positive subjects show a non-significant decrease of these values. These results suggest that gene(s) associated with HLA-DR could be one of the factors which affect blood levels of T cell subsets.
D006684:HLA-DR Antigens; D015798:HLA-DR1 Antigen; D015803:HLA-DR3 Antigen; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006801:Humans; D007958:Leukocyte Count; D010641:Phenotype; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
D006684:HLA-DR Antigens; D015798:HLA-DR1 Antigen; D015803:HLA-DR3 Antigen; D000949:Histocompatibility Antigens Class II