An ultrastructural and immunocytochemical study of a renal carcinoma secreting inactive renin.
This is a case report of a renal carcinoma which was secreting inactive renin. Using an antibody to human renin and the indirect immunoperoxidase technique, the renin-containing cells were localised within the tumour. These were found to be small granular cells situated in a perivascular position. The histological immunocytochemical and ultrastructural features of these cells are described.
D000230:Adenocarcinoma / Q000201:enzymology* / Q000378:metabolism / Q000648:ultrastructure; D000368:Aged; D006801:Humans; D007124:Immunoenzyme Techniques; D007668:Kidney / Q000201:enzymology / Q000648:ultrastructure; D007680:Kidney Neoplasms / Q000201:enzymology* / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D012083:Renin / Q000032:analysis / Q000378:metabolism*
D012083:Renin