title: Destructive arthritis due to silicone: a foreign-body reaction.
abstract: The authors report 3 cases of erosive arthritis resulting from a foreign-body reaction to a silicone implant in the wrist. No patient had a history of inflammatory arthritis. Radiographic changes included well-defined lytic lesions with thin, sclerotic margins, normal mineralization, and loss of volume of the implant. Pathologically, a destructive foreign-body reaction was seen, with intra- and extracellular silicone debris.
mesh_terms: D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects*; D011859:Radiography; D012826:Silicone Elastomers / Q000009:adverse effects*; D013585:Synovitis / Q000000981:diagnostic imaging / Q000209:etiology*; D014953:Wrist
chemical_list: D012826:Silicone Elastomers