Study of oxtriphylline SA in 50 asthmatics.
Fifty clinically stable patients with asthma on maintenance theophylline therapy, mean dose of 15 mg kg-1 per day, were switched to an equivalent dose (X 1.56) of oxtriphylline SA for seven doses. All subjects remained clinically stable after the change during the study period. Oxtriphylline SA appears to be useful for the maintenance treatment of asthma and can be safely substituted for other theophylline maintenance regimens.
D000328:Adult; D000368:Aged; D000628:Aminophylline / Q000627:therapeutic use; D001249:Asthma / Q000097:blood / Q000188:drug therapy*; D002794:Choline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013806:Theophylline / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use
D000628:Aminophylline; C012839:cholinophyllin; D013806:Theophylline; D002794:Choline