title: Glucose and insulin levels in duodenal ulcer disease before and after surgery.
abstract: Glucose and insulin responses to a standardized test meal in patients with chronic duodenal ulceration were measured pre-operatively and again post-operatively. An abnormal pre-operative glucose tolerance contributes to an even more deranged post-operative glucose tolerance. However, following administration of an alpha-glucosidase inhibitor, Acarbose, these post-operative abnormalities are markedly attenuated.
mesh_terms: D020909:Acarbose; D001786:Blood Glucose / Q000032:analysis*; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000097:blood* / Q000601:surgery; D005951:Glucose Tolerance Test; D065089:Glycoside Hydrolase Inhibitors; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D013997:Time Factors; D014312:Trisaccharides / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D065089:Glycoside Hydrolase Inhibitors; D007328:Insulin; D014312:Trisaccharides; D020909:Acarbose