title: [Fibrin-fibrinogen degradation products and pregnancy-specific beta 1-glycoprotein (SP 1) in normal and pathological pregnancies].
abstract: Fibrin-fibrinogen degradation products and SP 1 were measured in about 150 women with normal pregnancies. The mean levels of both parameters rose up to term. In 13 normal pregnancies the SP 1 course never decreased. Elevated levels of SP 1 were measured in 4 out of 10 cases of mild gestosis. In 11 cases of severe gestosis, however, 7 had increased values. A decrease of elevated levels correlated to a clinical deterioration. SP 1 was normal in the most cases of severe gestosis, but a fall of SP 1 indicated an impaired placental function resulting in small-for-date baby or imminent foetal asphyxia. The measurements of fibrinogen degradation products and of the course of SP 1 are helpful in the diagnosis of gestosis.
mesh_terms: D005260:Female; D005313:Fetal Death / Q000097:blood; D005317:Fetal Growth Retardation / Q000097:blood; D005337:Fibrin / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000378:metabolism*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000378:metabolism*; D012306:Risk
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins; D005337:Fibrin
vernacular_title: Fibrin-Fibrinogenspalt-produkte und schwanger-schaftsspezifisches beta 1-Glykoprotein (SP 1) bei normalen und pathologischen Schwangerschaften.