Effect of delayed-type hypersensitivity reaction and transferred lymphokine on the resistance of mice to Salmonella typhimurium infection.
Immune mice which exhibited a delayed-type hypersensitivity reaction to bovine serum albumin after bovine serum albumin immunization and stimulation and normal mice that had been transferred with a lymphokine-rich fraction from the supernatant of concanavalin A-stimulated spleen cell cultures demonstrated resistance to Salmonella infection.
D000818:Animals; D003208:Concanavalin A / Q000494:pharmacology; D006968:Hypersensitivity, Delayed; D007114:Immunization; D008099:Liver / Q000382:microbiology; D008222:Lymphokines / Q000494:pharmacology*; D016215:Macrophage-Activating Factors; D008264:Macrophages / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D012481:Salmonella Infections, Animal / Q000276:immunology*; D012486:Salmonella typhimurium / Q000254:growth & development; D012710:Serum Albumin, Bovine / Q000276:immunology; D013154:Spleen / Q000382:microbiology
D008222:Lymphokines; D016215:Macrophage-Activating Factors; D003208:Concanavalin A; D012710:Serum Albumin, Bovine