Exercise-induced asthma - laboratory observations.
The lability of the asthmatics ventilatory capacity, which is assessed during and after exercise (exercise-induced asthma (EIA) ), includes a rise during exercise and a fall after exercise. The importance of including both the rise and the fall in the calculation of the response is stressed. Ten exercise tests during one day did not exhaust the exercise-induced ventilatory lability in adult asthmatics. It is stressed that conclusive studies concerning the pretreatment of EIA must be placebo-controlled, double-blind. Inhaled beta-2-agonists were found to give better protection against EIA than intramuscular dosed beta-2-agonists. The inhalation of 2.5 mg terbutaline was equivalent to injecting about 1/4 mg of terbutaline as assessed by the cardiac effect.
D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D001250:Asthma, Exercise-Induced / Q000503:physiopathology*; D001985:Bronchial Provocation Tests; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D012119:Respiration; D013726:Terbutaline
D013726:Terbutaline