title: Upper gastrointestinal hemorrhage.
abstract: Hemorrhage in the upper gastrointestinal tract can be a diagnostic and therapeutic challenge to the physician. Although some advances have been made in patient care, mortality from gastrointestinal bleeding has not decreased during the past 40 years. The initial priorities in the physical examination of the bleeding patient should be a rapid assessment of the hemodynamic status and evaluation of the circulatory state. Once the patient has been hemodynamically stabilized, endoscopy is the best available technique for identifying the bleeding lesion. Potential sources of the bleeding are duodenal ulcers, gastric ulcers, Mallory-Weiss tears, and esophageal varices. The classic indications for surgical intervention are loss of 30% of the estimated blood volume in the first 24 hours, a need for 1,500 ml of transfused blood per 24 hours to maintain stable hemodynamics, hemorrhage to the point of hypotension or shock, and rebleeding during medical therapy.
mesh_terms: D004724:Endoscopy; D004932:Esophageal and Gastric Varices / Q000601:surgery; D004942:Esophagitis, Peptic / Q000150:complications; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000601:surgery / Q000628:therapy; D006431:Hemobilia / Q000150:complications; D006801:Humans; D008309:Mallory-Weiss Syndrome / Q000150:complications; D010437:Peptic Ulcer / Q000150:complications; D011170:Portasystemic Shunt, Surgical; D013312:Stress, Physiological / Q000150:complications; D014648:Varicose Veins / Q000601:surgery