title: Nuclear RNA-protein interactions and messenger RNA processing.
abstract: Eucaryotic messenger RNA precursors are processed in nuclear ribonucleoprotein particles (hnRNP). Here recent work on the structure of hnRNP is reviewed, with emphasis on function. Detailed analysis of a specific case, the altered assembly of hnRNP in heat-shocked Drosophila and mammalian cells, leads to a general hypothesis linking hnRNP structure and messenger RNA processing.
mesh_terms: D000818:Animals; D001483:Base Sequence; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D006358:Hot Temperature; D008957:Models, Genetic; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D012333:RNA, Messenger / Q000378:metabolism*; D012261:Ribonucleoproteins / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012333:RNA, Messenger; D012261:Ribonucleoproteins