Binding of immunoglobulins to protein A and immunoglobulin levels in mammalian sera.
The use of protein A from S. aureus (SpA) as an anti-IgG reagent in immunological techniques has extended in recent years, together with knowledge about its interaction with immunoglobulins of different species. Current data with respect to the binding of protein A to immunoglobulins and to the levels of immunoglobulins in the sera of some mammalian species are reviewed.
D000818:Animals; D002846:Chromatography, Affinity / Q000379:methods; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D007158:Immunologic Techniques; D013045:Species Specificity; D013205:Staphylococcal Protein A / Q000276:immunology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D013205:Staphylococcal Protein A; D007073:Immunoglobulin E