title: Computer averaging of 50 S ribosomal subunit electron micrographs.
abstract: Micrographs of one of the views of the large Escherichia coli subunit negatively stained with uranyl acetate were computer averaged using two techniques: the maximum-likelihood method and the correlation method. In both cases, extremely similar images were obtained. The same fine structure of the subunit has also been observed using optical averaging.
mesh_terms: D000818:Animals; D003201:Computers; D004926:Escherichia coli / Q000648:ultrastructure*; D008722:Methods; D008854:Microscopy, Electron; D051381:Rats; D012270:Ribosomes / Q000648:ultrastructure*