CRF-immunoreactive nerve fibers in the circumventricular organs of the monkey, Macaca fuscata.
The occurrence of CRF (corticotropin-releasing factor)-immunoreactive nerve fibers in the circumventricular organs of adult male monkeys, Macaca fuscata, was studied on serially sectioned brains, by means of the peroxidase-antiperoxidase technique in combination with a highly specific and sensitive CRF antiserum. CRF-containing nerve fibers were found in high concentrations in the infundibulum and, in addition, in small numbers in the posterior lobe, organum vasculosum laminae terminalis, subfornical organ, and area postrema; they were missing in the pineal body and the subcommissural organ. The CRF-immunoreactive nerve fibers distributed in these organs were located in the proximity of the blood vessels.
D000818:Animals; D001921:Brain / Q000166:cytology*; D001923:Brain Chemistry; D002552:Cerebral Ventricles / Q000166:cytology; D003346:Corticotropin-Releasing Hormone / Q000032:analysis*; D007124:Immunoenzyme Techniques; D008251:Macaca; D008297:Male; D009412:Nerve Fibers / Q000032:analysis*; D010870:Pineal Gland / Q000166:cytology; D010904:Pituitary Gland, Posterior / Q000294:innervation*; D013351:Subcommissural Organ / Q000166:cytology; D013356:Subfornical Organ / Q000166:cytology
D003346:Corticotropin-Releasing Hormone