title: [Effect of captopril on the level of arterial pressure and functional state of the kidney in symptomatic (renal) stable and malignant arterial hypertension].
abstract: Captopril was used in 21 patients with various forms of stable and malignant hypertension. In symptomatic hypertension the drug had a good antihypertensive effect. When applied in patients with essential hypertension caused by chronic diffuse glomerulonephritis or chronic pyelonephritis captopril neither increased pathological changes in the urine, nor inhibited renal function.
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002216:Captopril / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy; D006801:Humans; D006977:Hypertension, Renal / Q000188:drug therapy*; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D011392:Proline / Q000031:analogs & derivatives*; D011704:Pyelonephritis / Q000188:drug therapy; D014556:Urine / Q000032:analysis
chemical_list: D011392:Proline; D002216:Captopril; D011188:Potassium
vernacular_title: Vliianie kaptoprila na uroven' arterial'nogo davleniia i funktsional'noe sostoianie pochek pri simptomaticheskikh (pochechnykh) arterial'nykh gipertoniiakh stabil'nogo i zlokachestvennogo techeniia.