title: Limitations in the diagnosis of vesiculobullous diseases.
abstract: Study of vesiculobullous skin diseases by either clinical, histologic, or immunologic methods alone in an effort to make a specific diagnosis is fraught with limitations. Not only is it essential that all three methods be employed together in the endeavor to come to a specific diagnosis, but it is equally important that clinical history, including response to therapy and biologic course, be considered carefully.
mesh_terms: D005455:Fluorescent Antibody Technique; D006801:Humans; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology