Family history of hypertension and rates of sodium transport: absence of an association in population-based studies.
In a series of population-based studies, the relationship between a family history of hypertension and sodium transport was examined. In the total sample of 417 individuals, and in each sex-race-specific sub-sample, no significant differences were noted in red cell sodium-lithium countertransport, sodium concentration, or passive leak. A higher proportion of hypertensives was not found in the group with a positive family history, and blood pressures were only slightly higher in those--compared to those without--a positive family history. If family history of hypertension is associated with levels of countertransport, it would appear that the relationship is weak in the general population.
D000293:Adolescent; D000328:Adult; D001693:Biological Transport, Active; D002648:Child; D003430:Cross-Sectional Studies; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000235:genetics*; D007087:Illinois; D066298:In Vitro Techniques; D008094:Lithium / Q000097:blood; D012964:Sodium / Q000097:blood*; D013223:Statistics as Topic
D008094:Lithium; D012964:Sodium