Histocompatibility antigen patterns in Dupuytren's contracture.
Thirty-seven consecutive patients with Dupuytren's Contracture were investigated by tissue typing techniques to ascertain their HLA--A, B, C and DR antigen status. Whilst no definite HLA antigen was found in association with this disease, at least one possibly significant pattern of HLA DR antigens was found in these patients. This finding was also noted in patients with scleroderma, and the scleroderma-like syndrome induced by vinyl chloride exposure.
D000328:Adult; D000368:Aged; D002874:Chromosome Mapping; D004387:Dupuytren Contracture / Q000235:genetics* / Q000601:surgery; D005787:Gene Frequency; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics*; D015803:HLA-DR3 Antigen; D015804:HLA-DR4 Antigen; D006225:Hand / Q000601:surgery; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies
D005819:Genetic Markers; D006680:HLA Antigens; D015803:HLA-DR3 Antigen; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II