[Clinico-immunologic correlations in epilepsy].
In 51 epileptic patients with frequent attacks, the clinical manifestations were correlated with some parameters of immune responsiveness. The authors determined the content of plasma globulins of the main classes, cerebral antibodies, T and B lymphocytes, the rate of the inhibition of the leukocyte migration with respect to the cerebral antigen. Epilepsy was shown to run its course in the presence of immune responsiveness depression. A certain relationship existed between the duration of the disease, the endogenic factors, the nature of fits and some immunologic indices. With the development of the disease, the initial deficiency of the B lymphocyte immunity was coupled with the progressive dysfunction of the T lymphocyte immunity.
D001323:Autoantibodies / Q000032:analysis*; D001402:B-Lymphocytes; D001921:Brain / Q000276:immunology*; D002464:Cell Migration Inhibition; D004827:Epilepsy / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis*; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology*; D013601:T-Lymphocytes
D001323:Autoantibodies; D007136:Immunoglobulins
Kliniko-immunologicheskie korreliatsii pri épilepsii.