[Insulinotropic effect of diamicron after oral fructose tolerance test in patients with non-insulin-dependent diabetes mellitus].
Insulinotropic action of glucose after a glucose tolerance test and fructose after a fructose tolerance test as well as insulinotropic and hypoglycemic effects of diamicron were examined in 21 patients with type II diabetes mellitus. The data obtained indicate that insulinotropic and hyperglycemic activity of fructose yields to that of glucose. Apart from increasing insulin concentration in the blood, diamicron enhances glucose utilization at the periphery.
D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005632:Fructose; D005907:Gliclazide / Q000627:therapeutic use*; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia / Q000175:diagnosis / Q000188:drug therapy; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D008875:Middle Aged; D013453:Sulfonylurea Compounds / Q000627:therapeutic use*
D007328:Insulin; D013453:Sulfonylurea Compounds; D005632:Fructose; D005907:Gliclazide
Insulinotropnoe deĭstvie diamikrona na fone oral'nogo testa tolerantnosti k fruktoze u bol'nykh s insulinonezavisimym tipom sakharnogo diabeta.