The use of lithium during pregnancy and lactation.
Because of possible teratogenicity, lithium should be used during the first trimester only if clinically essential. Lithium levels should be monitored throughout pregnancy and dosage adjusted as necessary. Sodium-restricted diets and diuretics should be used with caution. Lithium dose should be reduced with the onset of labor. Mothers who choose to breast-feed should watch for signs of toxicity in their babies. With their consent, pregnant women on lithium should be reported to the American Register of Lithium Babies.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D001942:Breast Feeding; D004039:Diet, Sodium-Restricted / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005315:Fetal Diseases / Q000139:chemically induced; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D007774:Lactation; D008094:Lithium / Q000009:adverse effects* / Q000378:metabolism / Q000627:therapeutic use; D008431:Maternal-Fetal Exchange; D008895:Milk, Human / Q000378:metabolism; D011247:Pregnancy; D012042:Registries
D004232:Diuretics; D008094:Lithium