title: [Ultrastructural characteristics of malignant non-Hodgkin's lymphoma in baboons].
abstract: The ultrastructure of 29 malignant non-Hodgkin's lymphomas of baboons including prolymphocytic lymphoplasmacytic, lymphoblastic, and immunoblastic malignant lymphomas is described. The ultrastructure of the cells of B-cell malignant lymphomas is characterized by a more developed strands system of rough endoplasmic reticulum in the tumor cell cytoplasm and the presence of structural abnormalities in the protein synthesis in some B-cell malignant lymphoma cells in the form of Russell's and Dutcher bodies. Analogous baboon and human tumors were shown to have a high degree of cell ultrastructure similarity. Rare forms of baboon malignant non-Hodgkin's lymphomas including a large-cell variant of T-cell lymphoblastic lymphoma with large multilobated nuclei and a variety of B-cell lymphoma with an intermediate degree of cell differentiation have been found. Malignant lymphoma of large multilobated T-cell type and lymphoma of the intermediate lymphocytic type occur rarely in human pathology too.
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D004195:Disease Models, Animal; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D008198:Lymph Nodes / Q000648:ultrastructure*; D008228:Lymphoma, Non-Hodgkin / Q000648:ultrastructure*; D008928:Mitochondria / Q000648:ultrastructure; D010215:Papio; D013601:T-Lymphocytes / Q000648:ultrastructure
vernacular_title: Ul'trastrukturnaia kharakteristika zlokachestvennykh nekhodzhinskikh limfom pavianov.