[Hydroxylating activity of rat liver microsomes in the period of acute phase protein formation in radiation sickness].
At the height of radiation sickness (7-8 days after irradiation) the accretion of proteins of "acute phase" in rat blood was accompanied by diminution of diminution of hydroxylating activity of microsomes determined by the rate of aminopyrine demethylation. There was an invert correlation between these two indices, and the correlation coefficient was -0.9.
D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000818:Animals; D003037:Cobalt Radioisotopes; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003573:Cytochrome b Group / Q000378:metabolism; D015786:Cytochromes b5; D005720:Gamma Rays; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009961:Orosomucoid / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D003573:Cytochrome b Group; D008054:Lipid Peroxides; D009961:Orosomucoid; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; D000633:Aminopyrine N-Demethylase
Gidroksiliruiushchaia aktivnost' mikrosom pecheni krys v period obrazovaniia belkov "ostroĭ fazy" pri luchevoĭ bolezni.