title: Semi-crude human leukocyte interferon production in a simple medium.
abstract: Semi-crude human leukocyte interferon (specific activity at least 10(5) international units per mg protein) was produced by replacement of priming medium with protein poor medium before the production period. A simpler medium than Eagle's medium was suitable to obtain substantial quantities of interferon.
mesh_terms: D001769:Blood; D003470:Culture Media; D006801:Humans; D007370:Interferon Type I / Q000096:biosynthesis* / Q000302:isolation & purification; D007962:Leukocytes / Q000378:metabolism*; D010222:Parainfluenza Virus 1, Human / Q000502:physiology; D011506:Proteins / Q000494:pharmacology
chemical_list: D003470:Culture Media; D007370:Interferon Type I; D011506:Proteins