title: [Desamino-8-D-arginine vasopressin nose drops in the treatment of mild hemophilia A and von Willebrand's disease].
abstract: To permit home treatment in our patients we investigated the response to intranasal administration of 260 micrograms DDAVP in 28 patients with either mild hemophilia A or von Willebrand's disease. 6 patients with mild hemophilia A responded, and 6 did not. In the group with von Willebrand's disease 6 responded well, 4 responded partially and 6 did not respond. Knowledge of the severity of the disease did not allow us to predict the response, and therefore every patient should be tested individually. Intranasal DDAVP in our patients was used with success for bleeding into the knee joint, muscle hematoma and hematuria.
mesh_terms: D001127:Arginine Vasopressin / Q000627:therapeutic use*; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage / Q000627:therapeutic use*; D006467:Hemophilia A / Q000188:drug therapy*; D006801:Humans; D012996:Solutions; D014842:von Willebrand Diseases / Q000188:drug therapy*
chemical_list: D012996:Solutions; D001127:Arginine Vasopressin; D003894:Deamino Arginine Vasopressin
vernacular_title: Desamino-8-D-Arginin-Vasopressin-Nasentropfen zur Behandlung der milden Hämophilie A und des Morbus von Willebrand.