Orbital aspergillosis.
We treated a 40-year-old male who had orbital aspergillosis and presumed early intracranial extension with limited orbital exenteration and adjunctive amphotericin B. Forty-two months later the patient is alive without recurrence. Our patient illustrates the typical presentation of orbital aspergillosis with severe periorbital pain and proptosis; however, he did not have the usual concomitant sinusitis. Aggressive surgical and antifungal therapy in this case was successful in preventing further intracranial extension, which usually has a high mortality rate.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D001228:Aspergillosis / Q000175:diagnosis / Q000628:therapy*; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008297:Male; D009915:Orbit / Q000601:surgery; D009916:Orbital Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed
D000666:Amphotericin B