The clinical management of repeated early pregnancy wastage.
A rational systematic evaluation is essential to the management of a couple with repeated early pregnancy wastage. Psychologic support in the form of frequent discussions and sympathetic counseling are crucial to the successful evaluation and treatment of the anxious couple. A prompt and orderly evaluation will relieve anxiety. When no etiologic factor is identified, a 60% to 80% fetal salvage rate may be expected. Once a patient conceives, serial ultrasonography, beta-hCG determination, and estradiol determination may be useful in detecting the stage of the embryonic death if subsequent abortion occurs. A karyotypic analysis of the products of conception should be performed if fetal loss occurs.
D000026:Abortion, Habitual / Q000209:etiology* / Q000523:psychology; D001787:Blood Group Incompatibility / Q000150:complications; D018835:Chaperonin 10; D002869:Chromosome Aberrations / Q000150:complications; D025063:Chromosome Disorders; D003340:Corpus Luteum Maintenance; D004054:Diethylstilbestrol / Q000009:adverse effects; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007166:Immunosuppressive Agents; D007674:Kidney Diseases / Q000150:complications; D007889:Leiomyoma / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008285:Major Histocompatibility Complex; D010455:Peptides; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D011257:Pregnancy Proteins; D011254:Pregnancy in Diabetics; D011297:Prenatal Exposure Delayed Effects; D013491:Suppressor Factors, Immunologic; D013959:Thyroid Diseases / Q000150:complications; D014594:Uterine Neoplasms / Q000150:complications; D014599:Uterus / Q000002:abnormalities
D018835:Chaperonin 10; D007166:Immunosuppressive Agents; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor; D004054:Diethylstilbestrol