Ability of Post-endotoxin serum from BCG-infected mice to induce nonspecific resistance and stimulation of granulopoiesis.
Serum from BCG-infected mice obtained 2 h after injection with endotoxin induced elevated levels of colony-stimulating factor and an increase in splenic granulocyte-macrophage progenitor cells in C3H/HeJ mice. The capacity of such serum to stimulate granulopoiesis may be related to its ability to increase nonspecific resistance to lethal irradiation.
D000818:Animals; D003115:Colony-Stimulating Factors / Q000097:blood*; D004731:Endotoxins / Q000494:pharmacology*; D005260:Female; D006098:Granulocytes / Q000166:cytology*; D006410:Hematopoiesis; D051379:Mice; D008809:Mice, Inbred C3H; D009163:Mycobacterium bovis; D011836:Radiation Tolerance; D014376:Tuberculosis / Q000097:blood*
D003115:Colony-Stimulating Factors; D004731:Endotoxins