title: Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent.
abstract: A monoclonal antibody to the adenovirus 2 hexon protein was produced and characterized as a group-specific antibody. Positive reactivity in immunoprecipitation, indirect immunofluorescence, and radioimmunoassays was observed with human, canine, swine, bovine, murine, and simian adenoviruses. This monoclonal antibody should provide a specific and sensitive diagnostic reagent for detection of all mammalian adenoviruses.
mesh_terms: D000256:Adenoviridae / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral; D002213:Capsid / Q000276:immunology*; D036022:Capsid Proteins; D005455:Fluorescent Antibody Technique; D007118:Immunoassay; D011863:Radioimmunoassay; D014764:Viral Proteins / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D000956:Antigens, Viral; D036022:Capsid Proteins; D014764:Viral Proteins; C018315:hexon capsid protein, Adenovirus