In vitro stimulation of T-cell rosette formation by antiserum to thymus factor in Hodgkin's disease.
Patients with Hodgkin's disease manifest decreased percentage of E rosette-forming (T) lymphocytes in the peripheral blood. We have investigated thymosine-like factor in peripheral blood lymphocytes in these patients by immunofluorescence method. Some of lymphocytes showed the excess of thymosine-like factor. The addition of antiserum to thymus factor increased percentage of E rosette-forming (T) lymphocytes in the peripheral blood in Hodgkin's disease.
D000906:Antibodies; D004912:Erythrocytes / Q000276:immunology; D006689:Hodgkin Disease / Q000276:immunology*; D006801:Humans; D066298:In Vitro Techniques; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*; D013935:Thymic Factor, Circulating / Q000276:immunology*; D013951:Thymus Hormones / Q000276:immunology*
D000906:Antibodies; D013951:Thymus Hormones; D013935:Thymic Factor, Circulating