Homogenized milk and atherosclerotic disease: a review.
The theory that consumption of homogenized milk containing active xanthine oxidase is a causative factor in development of atherosclerosis is reviewed. Biologically available xanthine oxidase in consumed milk products may be absorbed in the small intestine and enter the blood stream. However, there appears to be no unequivocal evidence that the absorbed enzyme has any pathological effects that may contribute to development of atherosclerotic heart disease.
D000493:Allopurinol / Q000627:therapeutic use; D000787:Angina Pectoris / Q000188:drug therapy / Q000209:etiology; D000818:Animals; D001011:Aorta / Q000378:metabolism; D001161:Arteriosclerosis / Q000209:etiology*; D002417:Cattle; D005511:Food Handling / Q000379:methods; D006801:Humans; D006868:Hydrolysis; D007408:Intestinal Absorption; D008081:Liposomes; D008892:Milk / Q000009:adverse effects* / Q000201:enzymology; D009206:Myocardium / Q000378:metabolism; D010741:Phospholipases A / Q000378:metabolism; D010955:Plasmalogens / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D014969:Xanthine Oxidase / Q000009:adverse effects* / Q000378:metabolism
D008081:Liposomes; D010955:Plasmalogens; D000493:Allopurinol; D014969:Xanthine Oxidase; D010741:Phospholipases A