Thrombosis following phlebography with high-osmolar and low-osmolar contrast media.
In a prospective, randomised double blind study of 47 phlebographies, diatrizoate and ioxaglate were compared with regard to possible postphlebographic thrombosis proved by 125I-Fibrinogen uptake test. A significantly lower rate of postphlebographic thrombosis was registered when the low-osmolar ioxaglate was used.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000009:adverse effects*; D003973:Diatrizoate / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007463:Iodobenzoates / Q000009:adverse effects*; D007485:Ioxaglic Acid; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D010690:Phlebography / Q000009:adverse effects*; D011446:Prospective Studies; D011897:Random Allocation; D013924:Thrombophlebitis / Q000139:chemically induced*; D014283:Triiodobenzoic Acids / Q000009:adverse effects*
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D007485:Ioxaglic Acid