Nuclear translocation of the cytoplasmic glucocorticoid receptor in the iris-ciliary body and adjacent corneoscleral tissue of the rabbit following topical administration of various glucocorticoids. A rapid screening method for glucocorticoid activity.
D000287:Administration, Topical; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D003907:Dexamethasone / Q000008:administration & dosage / Q000031:analogs & derivatives; D004305:Dose-Response Relationship, Drug; D005123:Eye / Q000648:ultrastructure*; D005260:Female; D005469:Fluorometholone / Q000008:administration & dosage; D005938:Glucocorticoids / Q000008:administration & dosage*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives; D011282:Pregnenediones / Q000008:administration & dosage; D011817:Rabbits; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D013997:Time Factors
D005938:Glucocorticoids; D011282:Pregnenediones; D011965:Receptors, Glucocorticoid; D011987:Receptors, Steroid; C004180:dexamethasone 21-phosphate; D003907:Dexamethasone; C009935:prednisolone acetate; D011239:Prednisolone; C100283:medrysone; D005469:Fluorometholone