Pseudonodular T cell lymphoblastic lymphoma.
T cell lymphoblastic lymphoma usually presents as a rapidly growing lymphoma with histologic features of a diffuse, poorly-differentiated small cell lymphoma with a high mitotic rate. This report describes a patient who presented with an aggressive small cell lymphoma that morphologically had a nodular pattern. Repeated biopsy and use of cell surface markers resulted in reclassifying the cell type as T cell lymphoblastic and in recognizing the original pattern as pseudonodular. The routine application of these immunologic techniques in patients with lymphoma may lead to more accurate diagnoses and improved treatment.
D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D013601:T-Lymphocytes; D013899:Thoracic Neoplasms / Q000473:pathology