Occupational exposure to benzene, toluene and xylene and the T lymphocyte functions.
In 72 workers having occupational contact with benzene, toluene or xylene during 31 to 122 months, the T lymphocyte functions were evaluated. Workers after a service of 55-122 months showed a decreased T lymphocyte count without, however, alterations in their functions. No clinical signs of diminished immunological reactivity were noted in the subjects studied. The E rosette test is of importance in the evaluation of early effects on the lymphocyte system of the toxic action of benzene and its homologues.
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001554:Benzene / Q000009:adverse effects*; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D014050:Toluene / Q000009:adverse effects*; D014992:Xylenes / Q000009:adverse effects*
D000395:Air Pollutants, Occupational; D014992:Xylenes; D014050:Toluene; D001554:Benzene