Suppression of IgE antibody response by irradiated reticulum cell sarcoma cells in SJL mice.
A low number of highly irradiated spleen or lymph node cells from reticulum cell sarcoma (RCS)-bearing SJL mice brings about suppression of IgE antibody production in adequately immunized and sublethally irradiated recipients, probably by known proliferative action of RCS cells on the few Ly-1 T cells which escaped from the irradiation.
D000818:Animals; D005260:Female; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007165:Immunosuppression Therapy; D008198:Lymph Nodes / Q000166:cytology / Q000528:radiation effects; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology* / Q000532:radiotherapy; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000276:immunology* / Q000532:radiotherapy; D013154:Spleen / Q000166:cytology / Q000528:radiation effects
D007073:Immunoglobulin E