title: Therapeutic cytapheresis in chronic lymphocytic leukemia.
abstract: The role of therapeutic reductive lymphapheresis in 59 patients with chronic lymphocytic leukemia (CLL) was reviewed. Reduction in lymphocytosis, lymphadenopathy and hepatosplenomegaly was noted in 50%-60% of the patients studied. In addition to mobilization of the lymphoid tumor load, 40% of the patients showed an improvement in their hemogram. Although apheresis-induced anemia can occur, reported complications were minimal. These studies suggest that a majority of CLL patients might benefit from therapeutic lymphapheresis.
mesh_terms: D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology / Q000503:physiopathology; D001781:Blood Component Removal; D005069:Evaluation Studies as Topic; D005260:Female; D006400:Hematocrit; D006801:Humans; D007937:Leukapheresis / Q000009:adverse effects / Q000379:methods; D007945:Leukemia, Lymphoid / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010976:Platelet Count