[Comparative study of tinidazole and ornidazole for the prevention of septic complications of colonic surgery].
In a previous comparative study, authors have proved the significantly reduction of post-operative infections under elective colonic surgery by a preventive treatment with ornidazole IV (versus placebo). They have compared preventive effect of tinidazole IV short treatment (1,60 g in 24 h) and ornidazole (4 g in 4 days) in 2 randomised groups each of 20 patients. The same incidence of post-operative complications suggest an equal efficacy of two treatments.
D001424:Bacterial Infections / Q000517:prevention & control*; D003106:Colon / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009593:Nitroimidazoles / Q000627:therapeutic use*; D009950:Ornidazole / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication; D014011:Tinidazole / Q000627:therapeutic use*
D009593:Nitroimidazoles; D014011:Tinidazole; D009950:Ornidazole
Etude comparative tinidazole-ornidazole pour la prophylaxie des complications septiques de la chirurgie colique.