[Functioning of amino acid operons in Escherichia coli strains with an altered transcription and translation apparatus. I. The effect of mutations in gene rpsL coding ribosomal protein S12 on the functioning of the ilv operon].
Derepression of the ilv operon in rel strains of Escherichia coli is delayed when cells are transferred from rich to minimal medium and is completely blocked when the mixture of amino acids--serine, methionine and glycine is present in the minimal medium. It is shown that alterations in translation machinery caused by streptomycine resistance mutation can also lead to the delay of the ilv operon derepression in rel+ strains or to its complete inhibition in rel strains of E. coli. The possible mechanisms of high sensitivity of the ilv operon to different alterations in E. coli are discussed.
D000596:Amino Acids / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D029968:Escherichia coli Proteins; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D005815:Genetic Code; D009154:Mutation; D009876:Operon; D010641:Phenotype; D014176:Protein Biosynthesis; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins / Q000235:genetics*; D014158:Transcription, Genetic
D000596:Amino Acids; D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins; C000717190:RpsI protein, E coli
Funktsionirovanie aminokislotnykh operonov u shtammov Escherichia coli s izmenennym apparatom transkriptsii i transliatsii. Soobshchenie I. Vliianie mutatsiĭ v gene rpsL, kodiruiushchem ribosomnyĭ belok S12, na funktsionirovanie ilv-operona.