title: Mating types and serotypes of Cryptococcus neoformans isolated in Japan.
abstract: Thirty-two isolates of Cryptococcus neoformans from patients and one from the wild obtained in Japan were characterized for their serotype, self-fertility, and mating behaviour by crossing them with two mating types of Filobasidiella neoformans var. neoformans and F. neoformans var. bacillispora. Of the 32 isolates from patients, 31 were of serotype A and the remaining one was of serotype D. Although these 32 isolates were all self-sterile, 23 serotype A and one serotype D isolates produced a complete sexual state when mixed with the alpha mating type of F. neoformans var. neoformans. The one natural isolate was of serotype A-D and self-fertile. The Japanese clinical isolates of C. neoformans appear to be predominantly serotype A and alpha mating type of F. neoformans var. neoformans as is the case in the U.S.A.
mesh_terms: D003227:Conjugation, Genetic; D003433:Crosses, Genetic; D003453:Cryptococcosis / Q000382:microbiology*; D003454:Cryptococcus / Q000145:classification*; D003455:Cryptococcus neoformans / Q000145:classification* / Q000235:genetics; D006801:Humans; D007564:Japan; D012703:Serotyping