Overview of the current attempts toward the medical treatment of cataract.
A variety of agents are currently available that claim to either prevent, delay, or reverse cataracts associated with aging (senile cataracts), radiation, or diabetes and galactosemia (sugar cataracts). Senile cataract therapy includes formulation containing inorganic salts, nutritional supplements, natural product extracts, sulfhydryl, and sulfonic acid containing compounds and miscellaneous redox and nonsteroidal anti-inflammatory compounds. Agents associated with the treatment of radiation cataracts include anti oxidants and free radial scavengers. Aldose reductase inhibitors have been effective in the prevention of sugar cataracts. A summary of these agents and their potential ocular effects are presented.
D000375:Aging; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage; D002386:Cataract / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D002986:Clinical Trials as Topic; D048909:Diabetes Complications; D005693:Galactosemias / Q000150:complications; D006801:Humans; D007167:Immunotherapy; D009751:Nutritional Requirements; D009883:Ophthalmic Solutions; D010936:Plant Extracts; D011832:Radiation Injuries / Q000150:complications; D013455:Sulfur / Q000008:administration & dosage; D014815:Vitamins / Q000008:administration & dosage
D000975:Antioxidants; D009883:Ophthalmic Solutions; D010936:Plant Extracts; D014815:Vitamins; D013455:Sulfur