A crossover study comparing delayed radiohippurate images with furosemide renograms.
109 kidneys in 56 adult patients suspected of having urinary tract obstruction were studied prospectively. All patients underwent a routine 131I-hippurate series for 30 min, and to this was added a delayed image at 2 h. Later in the same day, these patients had a diuretic renogram for the first 30 min in which 40 mg of furosemide were injected simultaneously with a repeat 131I-hippurate dose. In 48 patients (85.7%) the delayed image and diuretic renogram showed mutual agreement as to the presence or absence of urinary tract obstruction, but not necessarily with the final diagnosis. Of the 8 remaining patients with 16 kidneys, there were 6 false positives and 4 false-negatives by diuretic renography, and 1 false positive and no false-negatives by nondiuretic delayed imaging. The only benefit derived from the diuretic renogram was a shortening of the examination from 2 h to 30 min.
D000328:Adult; D002986:Clinical Trials as Topic; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005665:Furosemide; D006801:Humans; D007465:Iodohippuric Acid; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011866:Radioisotope Renography / Q000379:methods*; D014570:Urologic Diseases / Q000175:diagnosis*
D007465:Iodohippuric Acid; D005665:Furosemide