title: Prostaglandins in ocular pathophysiology with special reference to diabetic retinopathy and glaucoma.
abstract: This report reviews evidence for influences of prostaglandins (PGs) on intraocular pressure in glaucoma and on the progressive vascular and blood cell dysfunction in diabetes mellitus, of which retinopathy is a manifestation, and includes a brief outline of evidence for roles of PGs in ocular inflammation. Sequences in pathways of biosynthesis and conversion of PGs are summarized, and PG assay methods are evaluated briefly.
mesh_terms: D000818:Animals; D001681:Biological Assay; D001791:Blood Platelet Disorders / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000503:physiopathology*; D004285:Dogs; D005123:Eye / Q000378:metabolism; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D011448:Prostaglandin Antagonists / Q000627:therapeutic use; D011453:Prostaglandins / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology*; D011817:Rabbits
chemical_list: D011448:Prostaglandin Antagonists; D011453:Prostaglandins