title: Effects of prostaglandins E2, I2 and D2 on pig nasal vasculature.
abstract: The effects of the prostaglandins (PG) E2, D2 and I2 were studied on the nasal vasculature of the anaesthetized pig. PGD2 caused vasoconstriction followed by a prolonged vasodilation whereas PGI2 only caused vasodilation. The effects of PGE2 were variable with vasoconstriction in 6 out of 7 pigs and vasodilation in 1 pig.
mesh_terms: D000818:Animals; D015232:Dinoprostone; D004837:Epinephrine / Q000494:pharmacology; D011464:Epoprostenol / Q000494:pharmacology*; D006801:Humans; D009666:Nose / Q000098:blood supply*; D015230:Prostaglandin D2; D011457:Prostaglandins D / Q000494:pharmacology*; D011458:Prostaglandins E / Q000494:pharmacology*; D013552:Swine / Q000502:physiology*; D014661:Vasoconstriction / Q000187:drug effects; D014664:Vasodilation / Q000187:drug effects
chemical_list: D011457:Prostaglandins D; D011458:Prostaglandins E; D011464:Epoprostenol; D015232:Dinoprostone; D015230:Prostaglandin D2; D004837:Epinephrine