title: [Coupling of transcription and translation as the factor regulating the transcription of genes rpoBC in Escherichia coli cells].
abstract: The natural transcription polarity of proximal and distal elements of the rplJL-rpoBC operon is increased when translation is inhibited in Escherichia coli cells. It is shown that transcription uncoupling to translation terminates within EcoRI-2,6 fragment of the operon which contains the transcription attenuator. We suggest that transcription attenuation in the rplJL-rpoBC operon is regulated by the coupling of transcription to translation of the intergenic fragment which overlaps the attenuator sequence.
mesh_terms: D002701:Chloramphenicol / Q000494:pharmacology; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005786:Gene Expression Regulation / Q000187:drug effects; D005798:Genes, Bacterial / Q000187:drug effects; D009693:Nucleic Acid Hybridization / Q000187:drug effects; D009876:Operon / Q000187:drug effects; D010957:Plasmids / Q000187:drug effects; D014176:Protein Biosynthesis / Q000187:drug effects; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D004269:DNA, Bacterial; D002701:Chloramphenicol
vernacular_title: Sopriazhenie transkriptsii i transliatsii kak faktor reguliatsii transkriptsii genov rpoBC v kletkakh Escherichia coli.