Regional cerebral perfusion imaging in the elderly.
Tomographic emission scintigraphy of the brain using a stationary gamma-camera and rotating slant hole collimator, following intravenous injection of 123I-n-isopropyl p-iodoamphetamine, yields high quality images of regional cerebral blood flow. The technique has been used on 20 geriatric patients and is non-invasive, well-tolerated, and hitherto only associated with trivial adverse effects. It appears to be particularly useful in supporting a clinical diagnosis of multi-infarct disease but the demonstration of zones of underperfused but not necessarily infarcted cerebral tissue may well have wider research implications.
D000368:Aged; D000662:Amphetamines; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D002544:Cerebral Infarction / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008875:Middle Aged; D014055:Tomography, Emission-Computed
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine