title: Bupivacaine anesthesia--a clinical trial for endodontic therapy.
abstract: In this double-blind clinical trial, thirty-two patients were randomly assigned to two groups of sixteen and administered 0.5 percent bupivacaine 1/200,000 epinephrine or 2 percent lidocaine 1/100,000 epinephrine for endodontic therapy. The onset and profundity of anesthesia were similar for the two groups. However, the bupivacaine group had prolonged anesthesia following treatment and a significant decrease in postoperative pain.
mesh_terms: D000328:Adult; D000368:Aged; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D002045:Bupivacaine / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control; D011897:Random Allocation; D012390:Root Canal Therapy; D013997:Time Factors
chemical_list: D002045:Bupivacaine