Surface antigens of metacyclic trypomastigotes of Trypanosoma cruzi.
The surface antigen makeup of metacyclic trypomastigote forms of strain G of Trypanosoma cruzi, which produce a subpatent infection in mice, differed from those of the virulent strains Y and CL. A 100,000-molecular-weight protein, barely detectable on the Y or CL cell surface, appeared as the main surface antigen of the G metacyclic trypomastigotes. In addition, the G metacyclic forms differed from those of the virulent strains in their susceptibility to complement-mediated immunolysis.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D003165:Complement System Proteins; D003602:Cytotoxicity, Immunologic; D051379:Mice; D008970:Molecular Weight; D014349:Trypanosoma cruzi / Q000276:immunology* / Q000472:pathogenicity
D000954:Antigens, Surface; D003165:Complement System Proteins