The immunohistological demonstration of carcinoembryonic antigen in intra-epithelial and invasive squamous carcinoma of the cervix.
Using the sensitive peroxidase, anti-peroxidase immunohistological technique, carcinoembryonic antigen (CEA) was studied in formalin-fixed, paraffin-embedded cervical specimens from 225 patients. CEA was demonstrated in 33% of moderate dysplasia, 78.5% of severe dysplasia, 79% of in-situ carcinoma and 78% of invasive carcinoma. CEA was not demonstrated in normal squamous epithelium, squamous metaplasia, reserve cell hyperplasia nor in mild dysplasia.
D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002278:Carcinoma in Situ / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D002462:Cell Membrane / Q000276:immunology; D002584:Cervix Uteri / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000276:immunology; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes / Q000276:immunology; D008207:Lymphatic Metastasis; D008679:Metaplasia / Q000276:immunology; D002578:Uterine Cervical Dysplasia / Q000276:immunology; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
D002272:Carcinoembryonic Antigen