Immunosuppressive properties of yeast extract.
Autolysate of yeast extract exhibits immunosuppressive properties. It inhibits phytohemagglutinin stimulated incorporation of 13C thymidine to rabbit lymphocytes. When administered to mice after immunization with sheep erythrocytes, it suppresses the appearance in the spleen of IgM antibody-producing cells (PFC). It also prolongs the survival time of skin allotransplants in mouse if given before and after transplantation.
D000190:Actinomyces / Q000276:immunology*; D000818:Animals; D002478:Cells, Cultured; D006085:Graft Survival; D007166:Immunosuppressive Agents; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D011817:Rabbits; D016038:Skin Transplantation
D007166:Immunosuppressive Agents