Immunochemical and immunocytochemical study of S-100 protein in rat adipocytes.
S-100 is a protein originally believed to be unique to the nervous system. We report here on the presence of S-100 in rat adipocytes, using immunohistochemical and immunochemical methods. We demonstrate that the protein in adipose tissue is present at a concentration comparable to that measured in the nervous tissue and is immunologically identical to brain S-100, indicating that the protein can no longer be regarded as being specific to the nervous system.
D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D007124:Immunoenzyme Techniques; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D051381:Rats; D009418:S100 Proteins / Q000378:metabolism*
D009419:Nerve Tissue Proteins; D009418:S100 Proteins