Taxonomic relationships among Clostridium novyi Types A and B, Clostridium haemolyticum and Clostridium botulinum type C.
The present study was undertaken to examine the genetic relationships among the closely related species, Clostridium novyi types A and B, C. haemolyticum and C. botulinum type C. These species were tested for DNA-DNA homology and thermostability of DNA duplexes and sorted into three genetically related groups: I, C. novyi type A; II, C. novyi type B, C. haemolyticum and one C. botulinum type C strain (Stockholm); III, the remaining C. botulinum type C strains. A few biochemical criteria corresponding to the genetic differences were recommended to differentiate each group. These studies imply that C. haemolyticum might be considered as C. novyi type D and that there are two genetically different groups in C. botulinum type C.
D001483:Base Sequence; D003013:Clostridium / Q000032:analysis / Q000145:classification* / Q000235:genetics; D003014:Clostridium botulinum / Q000032:analysis / Q000145:classification / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D009500:Neutralization Tests; D009692:Nucleic Acid Heteroduplexes; D009693:Nucleic Acid Hybridization
D004269:DNA, Bacterial; D009692:Nucleic Acid Heteroduplexes