title: [Drug therapy of peritonitis. 6-year experience with the chemotherapeutic agent and anti-endotoxin taurolin].
abstract: Since 1976 Taurolin is applied in clinical trials in several European states. The results being submitted show a very good activity of this substance against bacteria and endotoxin. Evaluating all clinical and experimental studies in our opinion the use of antibiotics postoperatively together with Taurolin seems to be an effective treatment of peritonitis. In our hospital taurolin has become an important part of the surgical management of severe forms of peritonitis. A development of resistant bacteria is not known up to now.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004322:Drainage; D006801:Humans; D007263:Infusions, Parenteral; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D013530:Surgical Wound Infection / Q000188:drug therapy; D013654:Taurine / Q000031:analogs & derivatives*; D007507:Therapeutic Irrigation; D013829:Thiadiazines / Q000627:therapeutic use*; D013843:Thiazines / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D013829:Thiadiazines; D013843:Thiazines; D013654:Taurine; C012566:taurolidine
vernacular_title: Medikamentöse Therapie der Peritonitis. 6 Jahre Erfahrung mit dem Chemotherapeutikum und Anti-Endotoxin Taurolin.