Retroviruses released from a human tumor xenograft in nude mice induce colony-stimulating factor (CSF) activity in human fibroblastic cells.
A human colony-stimulating factor (CSF)-producing tumor transplanted into athymic nude mice released retroviruses in vitro. The viruses induced CSF activity in human fibroblastic cell lines.
D000818:Animals; D002460:Cell Line; D003115:Colony-Stimulating Factors / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism* / Q000382:microbiology; D006801:Humans; D007890:Leiomyosarcoma / Q000378:metabolism; D008175:Lung Neoplasms / Q000382:microbiology*; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D012190:Retroviridae / Q000502:physiology*
D003115:Colony-Stimulating Factors