[Immunofluorescent morphometric studies of immunoglobulin-forming cells in small intestine biopsy specimens].
A simplified immunofluorescent morphometric technique for quantitative determination of immunoglobulin-forming cells (Ig-FC) in the small intestine mucosa was described. The following average values were established in 19 cases with chronic enteritis: total amount of Ig-FC: 117.5/0.1 mm2 villous area; IgA-FC = 78.4%, IgM-FC = 15.6%, and IgG-FC = 4.8%. An increased number of Ig-FC was found in a case with the syndrome of Peutz-Jeghers and in a case with alcoholic pancreatitis. Relatively high percentages of IgM-FC were established in two cases with long lasting chronic enterocolitis. The immunofluorescent study was performed simultaneously with the routine histology on the same biopsy specimens.
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001706:Biopsy; D002908:Chronic Disease; D004751:Enteritis / Q000276:immunology / Q000473:pathology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins / Q000096:biosynthesis*; D007421:Intestine, Small / Q000166:cytology / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
Immunfluoreszenz-morphometrische Untersuchungen der Immunglobulin-synthetisierenden Zellen in Dünndarm-Biopsien.