Antibodies to cardiac conducting tissue and abnormalities of cardiac conduction in rheumatoid arthritis.
The prevalence of antibodies to cardiac conducting tissue and cardiac conduction electrocardiographic abnormalities were studied in 60 patients with rheumatoid arthritis (RA). Complete or incomplete right bundle branch block (RBBB) was found in 21 patients (35%). Antibodies to cardiac conducting tissue were found in 16 (76%) of the 21 with RBBB and in eight (21%) of the 39 without RBBB. Cardiac conducting tissue antibodies (CCTA) were found only in one of 42 patients with RBBB unrelated to RA and in two out of 60 normal subjects. This newly documented immunological abnormality is thus correlated with disorder of conducting tissue.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000276:immunology*; D002037:Bundle-Branch Block / Q000209:etiology* / Q000276:immunology; D004562:Electrocardiography; D005260:Female; D005455:Fluorescent Antibody Technique; D006329:Heart Conduction System / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged
D000906:Antibodies