[Age-related characteristics of the effect of insulin on lipolysis and lipid peroxidation in the adipose tissue of rats].
In experiments on male rats, aged 4-5 and 24-26 months, the insulin effect on lipolysis and lipid peroxidation in the epididymal adipose tissue was studied in vivo and in vitro. Insulin was administered in doses of 0.5 and 2 U/g body weight and 0.025 and 0.1 U/ml. It was shown that insulin inhibits lipolysis and lipid peroxidation (malonic dialdehyde level was determined) in the adipose tissue. The antilipolytic and antioxidant effects decreased with age.
D000273:Adipose Tissue / Q000378:metabolism*; D000375:Aging; D000818:Animals; D007328:Insulin / Q000502:physiology*; D008054:Lipid Peroxides / Q000378:metabolism*; D008066:Lipolysis; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D051381:Rats
D007328:Insulin; D008054:Lipid Peroxides; D008315:Malondialdehyde
Vozrastnye osobennosti vliianiia insulina na lipoliz i perekisnoe okislenie lipidov v zhirovoĭ tkani krys.