Photobiological activity of 5,7-dimethoxycoumarin.
Some biological properties of 5,7-dimethoxycoumarin (DMC) include dark induced frameshift mutagenesis in bacteria, lethal photosensitization and the formation of sister chromatid exchanges in Chinese hamster cells. The number of sister chromatid exchanges per unit of cell lethality produced by DMC is almost the same as observed with 5-methoxypsoralen.
D000818:Animals; D002478:Cells, Cultured; D003374:Coumarins / Q000494:pharmacology*; D006224:Cricetinae; D003412:Cricetulus; D003434:Crossing Over, Genetic / Q000187:drug effects*; D004269:DNA, Bacterial / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics; D005260:Female; D011564:Furocoumarins / Q000494:pharmacology; D009153:Mutagens / Q000494:pharmacology; D010053:Ovary; D012854:Sister Chromatid Exchange / Q000187:drug effects* / Q000528:radiation effects; D014466:Ultraviolet Rays
D003374:Coumarins; D004269:DNA, Bacterial; D011564:Furocoumarins; D009153:Mutagens; C017104:3-carbethoxypsoralen; C037446:5,7-dimethoxycoumarin