Intracellular recordings from rat dorsolateral septal neurons, in vitro.
We have made intracellular recordings from the dorsolateral septal nucleus (DLSN) in a rat brain slice. DLSN neurons fire short tetrodotoxin (TTX) sensitive action potentials followed by an after-hyperpolarization. The action potential is followed by either a Ca2+-dependent depolarization or a Ca2+-dependent after-hyperpolarization. Stimulation of medial septum results in antidromic invasion of DLSN neurons while stimulation of the fimbria/fornix results in orthodromic EPSPs or action potentials.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001931:Brain Mapping; D002118:Calcium / Q000502:physiology; D005071:Evoked Potentials; D006624:Hippocampus / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012686:Septal Nuclei / Q000502:physiology*; D009435:Synaptic Transmission; D013779:Tetrodotoxin / Q000494:pharmacology
D013779:Tetrodotoxin; D002118:Calcium