title: [Lipid values and immune parameters in the course of viral hepatitis in patients with alcohol abuse and without alcohol stress in anamnesis].
abstract: The aim of the investigation was to estimate chosen parameters of fat balance and immunological reactivity in patients with virushepatitis and alcohol abuse (30 patients--I group), and without alcohol abuse in anamnesis (30 patients--II group). The investigations included the estimation of the presence of HBsAg in serum, the level of immunoglobulins IgG, IgA and IgM, the determination of T and B lymphocytes, the presence of organ-autoantibodies (SMA, ANA, AMA), the level of free fatty acids, triglycerides, full lipids, beta-lipoproteins and cholesterol in the blood serum. The rise in full lipids content in the blood serum, beta-lipoproteins, triglycerides, the increase of IgA level, the decrease of lymphocytes T percentage, more frequent confirmation of the presence of antimitochondrial autoantibodies were noted, especially in the group of patients with virushepatitis and alcohol abuse. Disturbances in fat balance remain in the convalescence period.
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007958:Leukocyte Count; D008055:Lipids / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology; D014280:Triglycerides / Q000097:blood
chemical_list: D001323:Autoantibodies; D005230:Fatty Acids, Nonesterified; D006514:Hepatitis B Surface Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008055:Lipids; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Lipidwerte und Immunparameter im Verlauf der Virushepatitis bei Patienten mit Alkoholabusus und ohne Alkoholbelastung in der Anamnese.