title: Fatty acid synthesis in adipose tissues of physically trained rats in vivo.
abstract: The effect of physical training on fatty acid synthesis in vivo was studied. After the rats had free access to a running wheel for 50 days, the rate of fatty acid synthesis estimated using 3H2O in adipose tissues of trained rats was about three times higher than that of sedentary rats in both the light and dark period. The rate of fatty acid synthesis in the liver but not in the brown adipose tissue was also slightly enhanced by physical training. The number of adipocytes was not affected, but the size of adipocytes was reduced by physical training. In trained rats, the rate of fatty acid synthesis in adipocytes whose diameter was similar to that of sedentary rats was about 10 times higher than that of sedentary rats. Within adipose tissue, the rate of fatty acid synthesis correlated positively to the diameter of adipocytes both in the sedentary and trained rats. These findings mean that the adaptive increase in fatty acid synthesis seen in adipocytes of trained rats is not secondary to the reduction in size of adipocytes.
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology / Q000502:physiology*; D002001:Adipose Tissue, Brown / Q000033:anatomy & histology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D005227:Fatty Acids / Q000096:biosynthesis*; D005260:Female; D007328:Insulin / Q000097:blood; D008099:Liver / Q000033:anatomy & histology; D009929:Organ Size; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
chemical_list: D001786:Blood Glucose; D005227:Fatty Acids; D007328:Insulin; D014316:Tritium