A double-blind trial of single-dose ciramadol for the treatment of post-episiotomy pain.
A randomized double-blind trial was carried out in 54 women to evaluate the effectiveness of ciramadol in a single (60 or 30 mg) oral dose regimen, compared with 60 mg codeine and placebo, in the treatment of post-episiotomy pain. Ciramadol gave a significantly better analgesic effect, at both 2 and 6 hours, and produced negligible side-effects. Codeine did less well than placebo in this study.
D000588:Amines / Q000627:therapeutic use*; D000700:Analgesics / Q000627:therapeutic use*; D001596:Benzylamines / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003061:Codeine / Q000627:therapeutic use; D004311:Double-Blind Method; D004841:Episiotomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy*; D011247:Pregnancy
D000588:Amines; D000700:Analgesics; D001596:Benzylamines; C018273:ciramadol; D003061:Codeine