title: Protection against acute, ascending pyelonephritis caused by Escherichia coli in rats, using isolated capsular antigen conjugated to bovine serum albumin.
abstract: We found that isolated Escherichia coli K13 antigen conjugated to bovine serum albumin, in contrast to isolated, non-conjugated K13, was highly immunogenic and induced protection against acute pyelonephritis caused by E. coli O6K13H1 in rats.
mesh_terms: D000208:Acute Disease; D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D000954:Antigens, Surface; D004927:Escherichia coli Infections / Q000276:immunology* / Q000517:prevention & control; D005260:Female; D011135:Polysaccharides, Bacterial / Q000276:immunology; D011704:Pyelonephritis / Q000276:immunology* / Q000517:prevention & control; D051381:Rats; D011919:Rats, Inbred Strains; D012710:Serum Albumin, Bovine / Q000276:immunology*
chemical_list: D000941:Antigens; D000942:Antigens, Bacterial; D000954:Antigens, Surface; C030659:K antigens; D011135:Polysaccharides, Bacterial; D012710:Serum Albumin, Bovine