The design, synthesis and development of a new class of potent antineoplastic anthraquinones.
D000818:Animals; D000880:Anthraquinones / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D002986:Clinical Trials as Topic; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D008942:Mitoxantrone / Q000031:analogs & derivatives; D010063:Ovum / Q000187:drug effects; D013329:Structure-Activity Relationship
D000880:Anthraquinones; D000970:Antineoplastic Agents; D008942:Mitoxantrone; C020182:ametantrone