[Stress thallium-201 myocardial emission CT: comparative evaluation with coronary arteriography and left ventriculography].
Thallium-201 emission computed tomography (ECT) using a rotating gamma camera was performed during stress and redistribution phases in 70 cases admitted for cardiac catheterization. A series of transaxial, ventricular short-axis, and long-axis sections were reconstructed, and segmental analysis was performed to predict individual coronary artery involvement. A perfusion defect was observed in 54 of 57 cases with coronary artery disease (95%). Ninety of 108 diseased coronary arteries (83%) were correctly identified (91% of single-vessel disease, 82% of two-vessel disease and 80% of three-vessel disease). No significant perfusion defect was seen in 11 of 13 cases with normal coronary arteries (specificity 85%). Number of diseased coronary arteries was accurately predicted in 78% of those with single-vessel disease, 65% of those with two-vessel disease and 47% of those with three-vessel disease, indicating relatively poor accuracy for predicting multivessel disease. The sensitivity for detecting individual coronary artery involvement was 90% for the right coronary artery (RCA), 89% for the left anterior descending artery (LAD) and 67% for the left circumflex artery (LCX). The specificity was 87%, 91%, and 100%, respectively. Even in those with three-vessel disease, a perfusion defect was seen in 82% of RCA and LAD segments, and 76% of LCX segment. Thus, there were high sensitivity and specificity for detecting individual coronary involvement by ECT imagings. Segmental analysis of ECT imagings was comparatively performed with the findings of contrast ventriculography. Normal wall motion was seen in 95% of normally perfused myocardial segments.(ABSTRACT TRUNCATED AT 250 WORDS)
D003327:Coronary Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D006321:Heart / Q000000981:diagnostic imaging*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D005082:Physical Exertion; D011868:Radioisotopes; D013793:Thallium; D014055:Tomography, Emission-Computed
D011868:Radioisotopes; D013793:Thallium