Halothane hepatotoxicity: relation between metabolic activation, hypoxia, covalent binding, lipid peroxidation and liver cell damage.
D000818:Animals; D001665:Binding Sites; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006221:Halothane / Q000378:metabolism / Q000633:toxicity*; D006801:Humans; D000860:Hypoxia / Q000378:metabolism*; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats
D008054:Lipid Peroxides; D003577:Cytochrome P-450 Enzyme System; D006221:Halothane