title: [Hormonal regulation of superoxide dismutase turnover in rat liver].
abstract: Insulin inhibited and glucagon stimulated degradation and biosynthesis of superoxide dismutase (SOD) in cytosol and mitochondrial fractions of rat liver tissue. At the same time, insulin increased turnover of SOD in motochondria. Hormones, administered into the animals, and the hormones secretion of which was stimulated by means of high doses of glucose (endogenous insulin) and of arginine (endogenous glucagon), affected dissimilarly the synthesis and degradation of individual enzymatic forms of SOD.
mesh_terms: D000818:Animals; D001120:Arginine / Q000494:pharmacology; D003600:Cytosol / Q000201:enzymology; D005934:Glucagon / Q000378:metabolism / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology; D007328:Insulin / Q000378:metabolism / Q000494:pharmacology*; D000078790:Insulin Secretion; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology; D051381:Rats; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism*
chemical_list: D007328:Insulin; D005934:Glucagon; D001120:Arginine; D013482:Superoxide Dismutase; D005947:Glucose
vernacular_title: Gormonal'naia reguliatsiia oborota superoksiddismutazy v pecheni krys.