title: [Comparative effectiveness of immunomodulators in the therapy of rheumatic heart defects].
abstract: A total of 166 patients with rheumatic heart diseases were examined. It was shown that the patients had secondary immune deficiency mainly with respect to the T-cells, which could not be eliminated with the routine therapeutic agents. The use of hemodes, decaris or sodium nucleinate in the combined therapy of such patients promoted correction of the immune deficiency and increased the treatment efficacy. Sodium nucleinate proved to be the most active.
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000276:immunology / Q000628:therapy; D007978:Levamisole / Q000627:therapeutic use; D008875:Middle Aged; D009696:Nucleic Acids / Q000627:therapeutic use; D011205:Povidone / Q000627:therapeutic use; D012214:Rheumatic Heart Disease / Q000276:immunology / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D009696:Nucleic Acids; D007978:Levamisole; C007918:hemodes; C013683:sodium nucleinate; D011205:Povidone
vernacular_title: Sravnitel'naia éffektivnost' nekotorykh immunomoduliatorov v terapii revmaticheskikh porokov serdtsa.