A protease is bound to rat liver nucleosomes.
Nucleosome prepared from pure rat liver nuclei contain protease activity. No protease is associated with nucleosome core particle and the protease-containing nucleosome has considerably higher sedimentation coefficient than the bulk nucleosomes. Only H1 histone is susceptible to the nucleosome-bound protease.
D000818:Animals; D006657:Histones / Q000378:metabolism; D008099:Liver / Q000201:enzymology*; D009707:Nucleosomes / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000378:metabolism*; D011480:Protease Inhibitors / Q000494:pharmacology; D051381:Rats
D006657:Histones; D009707:Nucleosomes; D011480:Protease Inhibitors; D010447:Peptide Hydrolases