title: [Enzyme-linked-immunosorbent assay (ELISA) for demonstrating antibodies against toxoplasmosis].
abstract: Serologic tests for specific antibodies are the primary method of diagnosis in suspected cases of toxoplasmosis. Available tests differ widely with regard to specificity and sensitivity. The enzyme-linked immunosorbent assay (ELISA) is specific for toxoplasmosis and has a sensitivity comparable to radio-immuno assays. The reproducibility of the CORDIA-T assay, tested by the authors in their laboratory, was excellent; the test itself was very easy to perform. When testing sera of 590 apparently normal subjects the authors found specific antibodies in 17.9% to 48.1% of all cases, depending on age. The ELISA-test seems to be useful in the diagnosis of ocular toxoplasmosis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007231:Infant, Newborn; D014122:Toxoplasma / Q000276:immunology*; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis*
chemical_list: D000906:Antibodies
vernacular_title: Enzyme-Linked-Immunosorbent-Assay (ELISA) zum Nachweis von Antikörpern gegen Toxoplasmose.