Improving success rates of kidney transplantation.
One-year patient survival rates have improved remarkably, from 84% in 1968 to 97% in 1980 for parental donor grafts, and from 65% to 90% for cadaver donor grafts. In contrast, graft survival rates showed a steady decline from 1968 to 1975 but subsequently improved at a rate of 2.4% per year for parent donor transplants and 2.7% per year for cadaver donor transplants. During this period of improving survival rates, the pretransplant transfusion exposure rate increased from 52% in 1977 to 91% by 1981. We conclude that transplantation has now reached a new level of acceptability as a clinical treatment modality and that blood transfusion has produced its effect on graft survival when results are disseminated over a large number of transplant centers.
D001803:Blood Transfusion; D002102:Cadaver; D003365:Costs and Cost Analysis; D006085:Graft Survival; D006648:Histocompatibility; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000601:surgery; D016030:Kidney Transplantation; D011182:Postoperative Care / Q000191:economics; D011300:Preoperative Care / Q000639:trends; D006435:Renal Dialysis; D014481:United States