Detection of circulating immune complexes in gynecological malignancies.
Extensive studies have demonstrated that immune complexes represent an important affidable tumor marker with a significant value as diagnostic and prognostic indicator of malignant diseases. In this view, we have studied a group of 11 healthy donors and a group of 11 patients with gynecological malignancies, pre- and post-operatively. Blood samples stored at -30 degrees C were tested by a new competitive immunoenzymatic assay (C3bi test). The data obtained, showed significant differences between healthy donors and tumor patients (p less than 0.001). Furthermore it is notable that the results obtained pre- and post-operatively could be proved with further longitudinal studies.
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000276:immunology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000276:immunology* / Q000601:surgery
D000936:Antigen-Antibody Complex