Report of a double-blind crossover study to compare flurbiprofen with paracetamol in the treatment of primary dysmenorrhoea.
Thirty-one patients suffering from primary dysmenorrhoea completed a double-blind crossover study which demonstrated flurbiprofen (100 mg three times a day) to be significantly more effective than paracetamol (1 g three The study revealed an explicit patient preference for flurbiprofen. The incidence of side-effect was low for both treatments though one patient was withdrawn because of lack of efficacy and side-effects while taking paracetamol.
D000082:Acetaminophen / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004412:Dysmenorrhea / Q000188:drug therapy*; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D009325:Nausea / Q000517:prevention & control; D010146:Pain / Q000188:drug therapy; D011422:Propionates / Q000627:therapeutic use*; D014839:Vomiting / Q000517:prevention & control
D011422:Propionates; D000082:Acetaminophen; D005480:Flurbiprofen