title: Detection of tissue polypeptide antigen in salivary glands and salivary gland tumors. An immunohistochemical study.
abstract: Tissue polypeptide antigen (TPA) was analyzed immunohistochemically in parotid gland tissue. This antigen, which is generally regarded as a proliferative antigen, was detected in the ductal system of the normal parotid gland. Parotid gland tumors were analyzed as well: pleomorphic adenomas; cystadenolymphomas; adenoid cystic carcinomas, and mucoepidermoid tumors. TPA could be found in distinct parts of every kind of tumor. However, apart from the TPA-positive cells, negative cells could be observed. The implications of these investigations are discussed.
mesh_terms: D000235:Adenolymphoma / Q000276:immunology; D008949:Adenoma, Pleomorphic / Q000276:immunology; D000951:Antigens, Neoplasm / Q000032:analysis*; D002277:Carcinoma / Q000276:immunology; D003528:Carcinoma, Adenoid Cystic / Q000276:immunology; D006801:Humans; D010306:Parotid Gland / Q000276:immunology*; D010307:Parotid Neoplasms / Q000276:immunology*; D010309:Parotitis / Q000276:immunology; D010455:Peptides / Q000276:immunology*; D019396:Tissue Polypeptide Antigen
chemical_list: D000951:Antigens, Neoplasm; D010455:Peptides; D019396:Tissue Polypeptide Antigen