[Aspects of an interplay between endocrinological and metabolic factors during birth].
The well-known rise of the levels of glucose, lactate, pyruvate, non-esterified free fatty acids (NFFA), glycerol, and ketone bodies during labour cannot be explained only by metabolic pathways. The simultaneous measurement of insulin, cortisol, hGH, and prolactin shows a striking change in secretion, especially of cortisol, after the first half of labour. It is assumed that cortisol plays an important part in the intrapartal metabolic conversions. The correlation cortisol/glucose becomes significant. There is no evidence of the known catabolic effect of cortisol under the conditions of labour, but these is evidence of a reduction of peripheral glucose utilisation. The role of cortisol for the intrapartal metabolic changes is discussed under the aspect of labour progress. The outlines of a very ingenious but also complex interplay between endocrinological and metabolic factors emerge which may provide useful tools for therapeutic use.
D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005260:Female; D005947:Glucose / Q000378:metabolism; D005990:Glycerol / Q000378:metabolism; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000502:physiology*; D007328:Insulin / Q000097:blood; D007657:Ketone Bodies / Q000378:metabolism; D007748:Labor Stage, Second; D007743:Labor, Obstetric; D007773:Lactates / Q000378:metabolism; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D011773:Pyruvates / Q000378:metabolism
D005230:Fatty Acids, Nonesterified; D007328:Insulin; D007657:Ketone Bodies; D007773:Lactates; D011773:Pyruvates; D011388:Prolactin; D013006:Growth Hormone; D005947:Glucose; D005990:Glycerol; D006854:Hydrocortisone
Aspekte des endokrin-metabolischen Zusammenspiels unter der Geburt.