title: A fluid exchange apparatus for the processing of biological specimens for electron microscopy.
abstract: A simple apparatus for the processing of biological specimens for electron microscopy is described. It comprises a fluid exchange chamber with associated reservoir. By carrying out all specimen processing from fixation to embedding in the exchange chamber and infiltrating the dehydrating and embedding mediums progressively, the handling and osmotic stresses associated with standard step processing are minimised.
mesh_terms: D003584:Cytological Techniques / Q000295:instrumentation*; D003890:Desiccation; D005404:Fixatives; D008854:Microscopy, Electron / Q000379:methods*; D013048:Specimen Handling / Q000295:instrumentation*
chemical_list: D005404:Fixatives