Glutathione bicarbonate Ringer's intraocular irrigation fluid. Prospective double-blind study.
In a prospective, double-blind, randomized, clinical trial, glutathione bicarbonate Ringer's (GBR) intraocular irrigation fluid was compared with Ringer's solution in 80 consecutive vitrectomies, with a mean follow-up of 5.8 months. No differences could be found with regard to visual acuity, corneal edema, anterior chamber flare, postoperative intraocular pressure greater than or equal to 30 mm Hg or phthisis bulbi. In this study, the superiority of GBR solution over Ringer's solution demonstrated in vitro could not be confirmed.
D001639:Bicarbonates / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004338:Drug Combinations / Q000627:therapeutic use; D005978:Glutathione / Q000627:therapeutic use*; D006801:Humans; D007430:Intraoperative Care; D007552:Isotonic Solutions / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D011183:Postoperative Complications; D000077331:Ringer's Solution; D007507:Therapeutic Irrigation / Q000379:methods*; D014822:Vitreous Body / Q000601:surgery*
D001639:Bicarbonates; D004338:Drug Combinations; D007552:Isotonic Solutions; D009883:Ophthalmic Solutions; C013003:glutathione-bicarbonate-Ringer solution; D000077331:Ringer's Solution; D005978:Glutathione