title: Human insulin. Facts and perspectives.
abstract: Recently an improved process for the production of human insulin from porcine insulin has been described. After being characterized, this insulin has been tested and shown to be safe and effective in diabetics in a short-term, double-blind, cross-over study. The availability of sufficient quantities of this human insulin now permits short- and long-term clinical investigations of the possible benefits of human insulin in the treatment of diabetics.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000188:drug therapy; D006801:Humans; D007328:Insulin / Q000008:administration & dosage* / Q000032:analysis / Q000138:chemical synthesis / Q000633:toxicity; D061389:Insulin, Regular, Pork; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D013552:Swine
chemical_list: D001786:Blood Glucose; D007328:Insulin; D061389:Insulin, Regular, Pork; C000006:insulin, neutral