Intraarterial infusion of urokinase in the treatment of acute pulmonary thromboembolism: preliminary observations.
Eleven patients were treated for acute pulmonary thromboembolism by perfusion of urokinase in the main pulmonary artery for a period of 12 hr with angiographic control. Clinical and radiologic improvement was achieved in all patients except for one in whom an embolectomy was later performed. The complications were similar to those for intravenous urokinase treatment, the most frequent being hemorrhage.
D000368:Aged; D010450:Endopeptidases / Q000627:therapeutic use*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D011655:Pulmonary Embolism / Q000188:drug therapy*; D011859:Radiography; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D010450:Endopeptidases; D014568:Urokinase-Type Plasminogen Activator