title: [Subcutaneous fat necrosis of the newborn infant. Apropos of 2 cases].
abstract: Two cases of subcutaneous fat necrosis of the newborn are reported, an infrequent disease characterized by nodules or cutaneous endurated plaques that appears a few days after birth, which histopathologic studies shows fat necrosis with formation of giant cells granulomas strange body type and the presence of needle shaped clefts corresponding to fat crystals. This is a benign disease that has to be to differentiated from sclerema neonatorum, a serious entity which coexists with another disease so we also think it could be more a symptom than an authentic thickness. The two entities are vinculated physiopathologically by the injury of the fat tissue with a minor quantity of oleic acid and a major relative proportion of palmitic and stearic acid; than that of the adult, which conditions its easy solidification.
mesh_terms: D005218:Fat Necrosis / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology*; D007249:Inflammation; D050356:Lipid Metabolism; D009336:Necrosis / Q000473:pathology*; D012593:Sclerema Neonatorum / Q000175:diagnosis
vernacular_title: Necrosis grasa subcutánea del recién nacido. A propósito de dos casos.