title: Effect of dietary fat on blood pressure in a rural Finnish population.
abstract: Thirty couples living in Liperi, a community of North Karelia, aged 40 to 50 yr participated in a dietary intervention study to assess the influence of dietary fat on blood pressure and other parameters. After a weeklong base-line period the subjects consumed a low fat diet (24% of energy) with a polyunsaturated/saturated fat ratio (P/S) of 1.2 for 6 wk. After this 6-wk intervention period the subjects resumed their normal diets (36% energy from fat, P/S 0.15) for an additional 6-wk period. Body weight remained constant throughout the study and salt intakes were approximately 12 g/day. During the low fat, high P/S period a decrease of 7.5 and 2.8 mm Hg pressure occurred for systolic and diastolic blood pressure from the base-line level. When the normal diet was resumed, systolic and diastolic blood pressures increased by 7.7 and 6.3 mm Hg, respectively, from the levels observed at the end of the intervention period.
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure / Q000187:drug effects*; D004041:Dietary Fats / Q000378:metabolism / Q000494:pharmacology*; D005224:Fats, Unsaturated / Q000494:pharmacology; D005227:Fatty Acids / Q000494:pharmacology; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood; D012424:Rural Population
chemical_list: D004041:Dietary Fats; D005224:Fats, Unsaturated; D005227:Fatty Acids; D000450:Aldosterone; D012083:Renin