title: Insulin does not play the major role in the refeeding stimulation of hepatic ornithine decarboxylase activity.
abstract: Pharmacologic doses of insulin stimulate hepatic ornithine decarboxylase activity. In an effort to see if changes of insulin levels in a physiologic range are also stimulatory, we tube fed 3-day fasted rats with pure carbohydrate, protein and fat meals. Only the protein meal was stimulatory in spite of the carbohydrate meal causing the largest increase in plasma insulin.
mesh_terms: D000818:Animals; D002262:Carboxy-Lyases / Q000378:metabolism*; D004032:Diet; D004789:Enzyme Activation; D005215:Fasting; D005502:Food; D007328:Insulin / Q000097:blood*; D008099:Liver / Q000201:enzymology*; D008297:Male; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D007328:Insulin; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase