[Quantification of lectin receptors on B, T, T-gamma, and T-mu lymphocytes. II. PHA, SBA, Dolichos biflorus, and Tetragonolobus purpureus].
Plasma membranes composition and structure of B, T, T gamma and T mu lymphocytes from peripheral blood have been studied using four 125I-labelled lectins. The results showed that B lymphocytes have a greater number of receptors for SBA and Dolichos biflorus lectins than T lymphocytes, whilst the opposite was observed for PHA-lectin. However, no significant differences between the two lymphocyte populations were found regarding the receptors for Tetragonolobus purpureus lectin. Among T lymphocyte subpopulations, SBA, Dolichos biflorus and tetragonolobus purpureus lectins appeared to have higher specificity for T gamma lymphocytes and PHA for T mu. PHA-lectin had greater affinity for B lymphocytes, while the rest showed higher affinity for T lymphocytes. The T gamma subpopulation had lower association constant for PHA-lectin than T mu lymphocytes, whilst the contrary was found to be true for the other three lectins.
D000116:Acetylgalactosamine / Q000276:immunology; D001402:B-Lymphocytes / Q000032:analysis; D005643:Fucose / Q000276:immunology; D006801:Humans; D037102:Lectins / Q000378:metabolism; D008214:Lymphocytes / Q000032:analysis*; D010835:Phytohemagglutinins / Q000378:metabolism; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000032:analysis* / Q000378:metabolism; D030262:Soybean Proteins; D013601:T-Lymphocytes / Q000032:analysis / Q000145:classification
C027654:Dolichos biflorus lectin receptor; D037102:Lectins; D010835:Phytohemagglutinins; D037121:Plant Lectins; D011975:Receptors, Mitogen; D030262:Soybean Proteins; C028824:soybean lectin; D005643:Fucose; D000116:Acetylgalactosamine
Cuantificación de receptores lectínicos en linfocitos B, T, T gamma y T mu. II. PHA, SBA, Dolichos biflorus y Tetragonolobus purpureus.