A monoclonal antibody against Mycobacterium lepraemurium which recognizes a cross-reacting mycobacterial antigen.
Spleen cells from BALB/c mice infected two weeks earlier with Mycobacterium lepraemurium were fused with myeloma cells, and, using an indirect immunofluorescence assay, a hybridoma was selected which secreted ananti-M. lepraemurium IgM antibody. In the same assay, this monoclonal antibody also recognized 17 other species of Mycobacteria (including M. leprae) and two strains of Nocardia.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis / Q000096:biosynthesis / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000096:biosynthesis / Q000276:immunology*; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000276:immunology*; D002459:Cell Fusion; D003429:Cross Reactions; D051379:Mice; D008807:Mice, Inbred BALB C; D009164:Mycobacterium Infections / Q000276:immunology*; D009167:Mycobacterium lepraemurium / Q000276:immunology; D051381:Rats; D013154:Spleen / Q000166:cytology
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial