[Effect of levamisole on cellular immunity indices in chronic bronchitis and chronic pneumonia patients].
Based on the study of the immune status in 133 subjects of whom 85 suffered from chronic bronchitis and chronic pneumonia and 50 comprised the group of normal subjects it could be established that patients with chronic bronchitis and chronic pneumonia showed a reduction in the blood of T and B lymphocytes. Administration of levamisole to patients with chronic pulmonary diseases led to an increase of the initially reduced T and B lymphocyte counts. The clinical improvement of patients induced by levamisole correlated with a positive time-course of changes in immunological characteristics. It is desirable that levamisole should be received by patients with low T lymphocyte counts.
D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D001991:Bronchitis / Q000188:drug therapy* / Q000276:immunology; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007136:Immunoglobulins / Q000032:analysis; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy* / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
D007136:Immunoglobulins; D007978:Levamisole
Izuchenie vliianiia levamizola na pokazateli kletochnogo immuniteta u bol'nykh khronicheskim bronkhitom i khronicheskoĭ pnevmonieĭ.