[Comparison of the therapeutic results in treating chronic myelosis with splenic irradiation or busulfan].
In a retrospective study the survival of 111 patients with chronic myeloid leukemia was analyzed. There was a slight superiority of the patients primarily treated with busulfan over those first getting splenic irradiation and busulfan subsequently. This difference was statistically not significant. If spleen size prior to treatment was less than 10 cm below left costal margin, there was also a tendency in favor of primary busulfan therapy. In patients having bigger spleens, neither form of treatment had any advantage.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002066:Busulfan / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013154:Spleen / Q000528:radiation effects*; D013997:Time Factors
D002066:Busulfan
Vergleich der Therapieergebnisse bei der Behandlung der chronischen Myelose mit Milzbestrahlung oder Busulfan.