Colonial variation in Serratia marcescens together with antibiotic resistance.
A strain of Serratia marcescens, isolated from the blood cultures of a patient receiving antibiotics, exhibited 3 unstable properties. These properties were resistance to aminoglycosides, colony size and pigment production. While resistance to aminoglycosides was linked to colony size, pigment production appeared independent of the other 2 properties. When multiple variation of properties occurs in colonies isolated from clinical material, this still may represent a pure culture.
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D014644:Genetic Variation / Q000187:drug effects*; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D007951:Leukemia, Myeloid / Q000382:microbiology; D010858:Pigmentation; D012706:Serratia marcescens / Q000187:drug effects / Q000235:genetics*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005839:Gentamicins