title: Serum theophylline assay by rate nephelometric inhibition immunoassay: a comparison with high-performance liquid chromatography.
abstract: The reliability of two clinical laboratory methods for assaying theophylline in serum is compared. Analysis of serum-based standards and 70 patient specimens by rate nephelometric inhibition immunoassay (NIIA) and by high-performance liquid chromatography (HPLC) demonstrates that both methods have comparable random analytical variation. The results indicate that NIIA is a reliable method for measuring serum theophylline and may serve as a practical alternative to the HPLC method.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D006801:Humans; D007158:Immunologic Techniques; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D013806:Theophylline / Q000097:blood* / Q000276:immunology
chemical_list: D013806:Theophylline