title: [Microbiological synthesis of tetrapyrrole compounds].
abstract: This paper reviews publications on the biosynthesis of functional tetrapyrroles by microorganisms. Emphasis is given to the structure of uroporphyrin III methylated derivatives termed corriphyrins and their involvement in the formation of two groups of tetrapyrrole pigments--corrinoids and siroheme. Current concepts concerning the final stages of the formation of the corrine ring and potential cobalt-free precursors of vitamin B12 are discussed. It is indicated that the data available may help elucidate evolutionary and biogenetic patterns in the emergence and interaction of tetrapyrrole compounds and formulate problems of practical importance.
mesh_terms: D001202:Ascitic Fluid / Q000378:metabolism; D001419:Bacteria / Q000378:metabolism*; D003013:Clostridium / Q000378:metabolism; D045728:Corrinoids; D003901:Desulfovibrio / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D007783:Lactones / Q000378:metabolism; D008745:Methylation; D011424:Propionibacterium / Q000378:metabolism; D011758:Pyrroles / Q000096:biosynthesis*; D013054:Spectrophotometry, Atomic; D013329:Structure-Activity Relationship; D045725:Tetrapyrroles; D014578:Uroporphyrins / Q000096:biosynthesis; D014805:Vitamin B 12 / Q000031:analogs & derivatives / Q000096:biosynthesis
chemical_list: D045728:Corrinoids; D007783:Lactones; D011758:Pyrroles; D045725:Tetrapyrroles; D014578:Uroporphyrins; C022181:uroporphyrin III; C010895:cobyrinic acid; D014805:Vitamin B 12
vernacular_title: Mikrobiologicheskiĭ sintez tetrapirrol'nykh soedineniĭ.