title: Ankylosing spondylitis, Reiter's syndrome, psoriatic arthritis, and arthritis of inflammatory bowel disease.
abstract: These diseases are classified together as the seronegative spondyloarthritides. They are characterized by an association with the cell surface antigen HLA-B27, sacroilitis and spondylitis, inflammatory peripheral arthritis, enthesopathy (abnormalities in ligamentous attachments), and the absence of rheumatoid factor. Extra-articular complications are common. The diseases are usually treated with nonsteroidal anti-inflammatory drugs and physical therapy.
mesh_terms: D001168:Arthritis / Q000175:diagnosis* / Q000209:etiology; D016918:Arthritis, Reactive / Q000175:diagnosis*; D003093:Colitis, Ulcerative / Q000150:complications*; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D015796:HLA-B27 Antigen; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000175:diagnosis*; D013167:Spondylitis, Ankylosing / Q000175:diagnosis*
chemical_list: D006680:HLA Antigens; D015796:HLA-B27 Antigen