Reaginic and non-reaginic antibodies against mammalian danders.
Solid phase enzyme immunoassay (EIA) and passive haemagglutination techniques were used to study the occurrence of IgG-type antibodies against feline and bovine epithelial extracts among RAST-positive patients, senior veterinary students, cat fanciers (representing exposed subjects) and healthy controls. In most groups both techniques exhibited equal sensitivity being positive in about half of the RAST-positive cases. The levels of both EIA-reactive IgG-class and IgA-class antibodies were increased in most of the sera (greater than mean + 2 s.d. of controls), while only a few sera showed increased IgM values.
D000818:Animals; D000906:Antibodies / Q000032:analysis*; D002415:Cats; D002417:Cattle; D004848:Epithelium / Q000276:immunology; D005260:Female; D006197:Hair / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis; D011247:Pregnancy; D011852:Radioallergosorbent Test; D011935:Reagins / Q000032:analysis*
D000906:Antibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011935:Reagins