Hereditary retinoblastoma and 13q--mosaicism.
Mosaicism for a 13q interstitial deletion was found in a minor fraction of peripheral blood lymphocytes in a 10-month-old girl affected with bilateral retinoblastoma. The tumor was inherited from the unilaterally affected father.
D000328:Adult; D002872:Chromosome Deletion; D002901:Chromosomes, Human, 13-15 / Q000648:ultrastructure*; D005134:Eye Neoplasms / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D009030:Mosaicism; D012175:Retinoblastoma / Q000235:genetics*