Degradation of crystalline ergocalciferol [vitamin D2, (3 beta,5Z,22E)-9,10-secoergosta-5,7,10(19),22-tetra en-3-ol].
The products of the degradation of crystalline ergocalciferol were investigated. These studies showed that numerous acidic and neutral oxidation products were formed resulting in the complete destruction of the triene functionality. Separation of the neutral products by preparative TLC led to material identified as the Windaus ketone IIa, 2,3,3a,4,5,6,7,7a beta-octahydro-7a alpha-methyl-1R-(1 alpha,1R,4R,5-trimethyl-2E-hexenyl)-4H-inden-4-one.
D002855:Chromatography, Thin Layer; D003460:Crystallization; D004872:Ergocalciferols / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D013055:Spectrophotometry, Infrared
D004872:Ergocalciferols