title: Genetic variants of human B component (BF system) and alpha-1-antitrypsin (PI system) in a population from Sardinia.
abstract: BF- and PI-type determinations have been performed in a population from Sardinia. The corresponding allele frequencies are as follows: BF*S = 0.5783, BF*F = 0.2189, BF*SO7 = 0.0046, BF*F1 = 0.1982 and PI*M1 = 0.5872, PI*M2 = 0.2041, PI*M3 = 0.0459, PI*M4 = 0.0940, PI*S = 0.0619, PI*Z = 0.0046, PI*N = 0.0023. Whereas the BF system shows the originality of the Sardinian population with a very high BF*F1 allele frequency, the PI system does not reveal any characteristic features.
mesh_terms: D000483:Alleles; D011415:Complement Factor B / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D007558:Italy; D011110:Polymorphism, Genetic; D000515:alpha 1-Antitrypsin / Q000235:genetics*
chemical_list: D004792:Enzyme Precursors; D000515:alpha 1-Antitrypsin; D011415:Complement Factor B