Marrow transplantation for patients with acute lymphoblastic leukemia: a long-term follow-up.
Twenty-two patients with acute lymphoblastic leukemia in second or subsequent remission and 26 with acute lymphoblastic leukemia in relapse were given cyclophosphamide (60 mg/kg on each of 2 days), total body irradiation (920 rad), and marrow transplants from HLA-identical siblings. With a minimum follow-up of more than 5 yr, an actuarial analysis shows a survival and apparent cure of 27% of the patients transplanted in remission and 15% of the patients transplanted in relapse.
D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy*; D011379:Prognosis; D014916:Whole-Body Irradiation
D003520:Cyclophosphamide