Prostaglandins and cancer.
This paper reviews the role of prostaglandins (PGs) in cancer. Specific topics of discussion include: (1) the potential use of PGs as tumor markers, (2) PG mediation of hypercalcemia of cancer, and (3) the use of PG synthesis inhibitors in cancer therapy.
D000818:Animals; D001859:Bone Neoplasms / Q000378:metabolism / Q000556:secondary; D001862:Bone Resorption / Q000187:drug effects; D001943:Breast Neoplasms / Q000378:metabolism / Q000601:surgery; D015232:Dinoprostone; D005260:Female; D005833:Genital Neoplasms, Female / Q000378:metabolism; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology; D007213:Indomethacin / Q000008:administration & dosage; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology*; D011448:Prostaglandin Antagonists / Q000008:administration & dosage; D011453:Prostaglandins / Q000096:biosynthesis / Q000097:blood / Q000502:physiology*; D011458:Prostaglandins E / Q000096:biosynthesis; D011460:Prostaglandins F / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis
D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D015232:Dinoprostone; C100006:prostaglandin F1; D007213:Indomethacin