title: [Reaction of the whole body to auxiliary liver transplantation].
abstract: Changes of hemoglobin, hematocrit, blood pressure, blood lactate concentration, and blood pyruvate concentration, as well as in the acid-base balance, the electrolyte metabolism, and the enzyme activities into the serum were investigated in auxiliary liver transplantation in 5 dogs. Transitory hypokalemia and hypoglycemia, a slight controllable acidosis caused by lactate accumulation, as well as a strong short-term increase of the enzyme activities in the serum are an expression of the functioning of the transplanted liver. Hyperkalemia, a massive increase of the blood lactate concentration with uncontrollable acidosis, a therapy-resistant depression in blood pressure, and a slow continuous increase of the enzyme activities in the serum are symptoms of the irreversible ischemic damage of the transplanted liver. The avoidance of an irreversible ischemic damage during the preservation, the maintenance of a normal blood pressure after the transplantation, as well as the compensation of acidosis, hypoglycemia, and hypokalemia are of decisive importance for a successful liver transplantation.
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D004734:Energy Metabolism; D004798:Enzymes / Q000097:blood; D005260:Female; D006400:Hematocrit; D006439:Hemodynamics; D006452:Hemoglobinometry; D006498:Hepatectomy; D007511:Ischemia / Q000201:enzymology; D007773:Lactates / Q000097:blood; D008099:Liver / Q000098:blood supply; D016031:Liver Transplantation; D008297:Male; D009926:Organ Preservation; D011183:Postoperative Complications / Q000097:blood; D011773:Pyruvates / Q000097:blood; D014882:Water-Electrolyte Balance
chemical_list: D004798:Enzymes; D007773:Lactates; D011773:Pyruvates
vernacular_title: Die Reaktion des Gesamtorganismus auf eine auxiliäre Lebertransplantation.