Effect of lecithin on memory in normal adults.
In a double-blind, placebo-controlled, crossover study of the effect of lecithin on memory test performance, nine normal paid volunteers (age range = 22-55 years) took single oral doses of placebo and lecithin (20 g) 5 hours before cognitive testing. Lecithin raised plasma choline levels during the test session to nearly double the placebo levels, but a categorized serial learning task, a word recognition task, a paired associates learning task, and a test of retrieval by category demonstrated no significant change in memory performance. Lecithin did not selectively enhance memory for low-imagery words. Lecithin also had no effect on psychomotor speed.
D000328:Adult; D002794:Choline / Q000097:blood; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects*; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000494:pharmacology*; D010919:Placebos; D011581:Psychological Tests; D011597:Psychomotor Performance / Q000187:drug effects
D010713:Phosphatidylcholines; D010919:Placebos; D002794:Choline