Late effects of treatment of cancer in children.
Advances in surgical techniques, in chemotherapy, and in radiation therapy have led to improved survival in children treated for cancer. Children cured of cancer will soon form a significant fraction of our adult population. As we follow such survivors, we have become more aware of long-term side effects of treatment. This is not a reason to withhold therapy. Instead, careful followup of oncology patients is needed to document the late effects, to identify the etiologic agents, and to alter treatment to give the least toxic therapy without sacrificing quality or duration of survival.
D001842:Bone and Bones / Q000187:drug effects / Q000528:radiation effects; D002319:Cardiovascular System / Q000187:drug effects / Q000528:radiation effects; D002648:Child; D004064:Digestive System / Q000187:drug effects / Q000528:radiation effects; D004359:Drug Therapy, Combination / Q000009:adverse effects*; D004702:Endocrine Glands / Q000187:drug effects / Q000528:radiation effects; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000150:complications / Q000628:therapy*; D009420:Nervous System / Q000187:drug effects / Q000528:radiation effects; D011878:Radiotherapy / Q000009:adverse effects*; D012137:Respiratory System / Q000187:drug effects / Q000528:radiation effects; D014566:Urogenital System / Q000187:drug effects / Q000528:radiation effects