Identification and mapping of Lm-1, an Igh-linked locus for a murine alloantigen.
Analyzing Igh congenic, Igh recombinant, and recombinant inbred mouse strains with a cytotoxic T-cell assay, we have identified and mapped an Igh-linked locus (Lm-1) that codes for a cell-surface alloantigen (Lm-1). Lm-1 maps 5 units telomeric to Pre-1 and is genetically distinct from previously described Igh-linked loci. The importance of Lm-1 and its possible relationship to other Igh-linked alloantigens is discussed.
D000818:Animals; D000954:Antigens, Surface / Q000235:genetics*; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D003602:Cytotoxicity, Immunologic; D008040:Genetic Linkage; D007519:Isoantigens / Q000235:genetics*; D051379:Mice; D008805:Mice, Inbred A / Q000276:immunology; D008807:Mice, Inbred BALB C / Q000276:immunology; D008810:Mice, Inbred C57BL / Q000276:immunology; D008815:Mice, Inbred Strains / Q000276:immunology*; D013045:Species Specificity; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
D000954:Antigens, Surface; D007519:Isoantigens