[Effect of nembutal on inhibitory responses of neurons of an isolated strip of cat auditory cortex induced by intracortical stimulation].
Neuronal responses in acute isolated slab of the auditory cortex (AI zone) to intracortical stimulation were studied intracellularly in experiments on nembutal anaesthetized cats. It was found that 77% of the neuronal responses were primary IPSPs, and taking into consideration secondary inhibitory responses 92% of neurons exhibited inhibition. All types of neuronal responses in the slab had short latencies. The longest latent period did not exceed 5 ms. Neurons responding by IPSPs to intracortical stimulation were found throughout the depth of the slab. Their distribution was analysed in connection with amplitude and latencies of inhibitory responses. Mechanisms of barbiturate influence on some characteristics of inhibitory responses, particularly on amplitude and duration of IPSPs and their latent periods are discussed.
D000818:Animals; D001303:Auditory Cortex / Q000187:drug effects*; D002415:Cats; D004558:Electric Stimulation; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D009433:Neural Inhibition / Q000187:drug effects*; D010424:Pentobarbital / Q000494:pharmacology*; D011930:Reaction Time / Q000187:drug effects; D009435:Synaptic Transmission / Q000187:drug effects
D010424:Pentobarbital
Vliianie nembutala na reaktsii tormozheniia neĭronov izolirovannoĭ poloski slukhovoĭ kory mozga koshki, vyzvannye vnutrikorkovym razdrazheniem.