title: Replication of Paget cells in mammary and extramammary Paget's disease.
abstract: Replication of Paget cells in mammary and extramammary Paget's disease was evaluated by autoradiography after incorporation of tritiated thymidine. Neoplastic cells proliferated in the deepest layers of the epidermis suggesting a topographical control of their multiplication similar to that of the normal epidermis.
mesh_terms: D000328:Adult; D000368:Aged; D001345:Autoradiography; D001943:Breast Neoplasms / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology*; D002455:Cell Division; D004727:Endothelium / Q000473:pathology; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D008940:Mitotic Index; D010145:Paget Disease, Extramammary / Q000473:pathology*; D010144:Paget's Disease, Mammary / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology