title: [Pathogenesis and therapy of rupture of the transplanted kidney. Experiences in 186 transplantations].
abstract: Ruptures after kidney transplantations within the first two postoperative weeks were observed in 10.5% in adults and in 12.1% in children. In all cases acute rejection was demonstrable histologically. Immediately following diagnosis and intraoperatively at the latest first measures consisted of treatment of rejection using methylprednisolone as bolus. Operative care was always successful if visible detumescence of the organ following bolus treatment occurred. In one case surgery could be evaded by early treatment of rejection. Successfully treated ruptured kidneys do not differ in their long term results from kidneys which have undergone acute rejection in the early stage after transplantation. Rupture of the transplant is interpreted as special form of acute rejection.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007674:Kidney Diseases; D016030:Kidney Transplantation; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy; D012422:Rupture, Spontaneous
chemical_list: D008775:Methylprednisolone
vernacular_title: Pathogenese und Therapie der Ruptur transplantierter Nieren.