title: Radiation absorbed doses from iron-52, iron-55, and iron-59 used to study ferrokinetics.
abstract: Biological data obtained principally with Fe-59 citrate are used with physical data to calculate radiation absorbed doses for ionic or weak chelate forms of Fe-52, Fe-55, and Fe-59, administered by intravenous injection. Doses are calculated for normal subjects, primary hemochromatosis (also called idiopathic or hereditary hemochromatosis), pernicious anemia in relapse, iron-deficiency anemia, and polycythemia vera. The Fe-52 doses include the dose from the Mn-52m daughter generated after injection of Fe-52. Special attention has been given to the dose to the spleen, which has a relatively high concentration of RBCs and therefore of radioiron, and which varies significantly in size in both health and disease.
mesh_terms: D003201:Computers; D005260:Female; D006801:Humans; D007501:Iron / Q000378:metabolism*; D007504:Iron Radioisotopes; D007700:Kinetics; D008297:Male; D008345:Manganese; D008954:Models, Biological; D011829:Radiation Dosage; D011868:Radioisotopes
chemical_list: D007504:Iron Radioisotopes; D011868:Radioisotopes; D008345:Manganese; D007501:Iron