T cell chronic lymphocytic leukemia with bullous manifestations.
Among chronic lymphocytic leukemias (CLLs), the B cell variant is the most common phenotype. The T cell is rare. A variety of cutaneous manifestations have been reported with B and T cell leukemias. We report a patient who presented with a bullous eruption and who was found to have T cell CLL. Despite different therapeutic approaches, the patient died. The cutaneous histology and autopsy findings are reviewed.
D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology*; D013601:T-Lymphocytes / Q000648:ultrastructure*