title: Assignment of the haemophilia B (factor IX) locus to the q26-qter region of the X chromosome.
abstract: Two independent approaches have provided an assignment for the factor IX (Haemophilia B) locus to Xq26-qter, the distal region of the X chromosome long arm. Cloned DNA sequences of the gene were hybridized to restriction enzyme digests of DNA prepared from a series of somatic cell hybrids containing different X-chromosomal regions and also in situ to prepared metaphase chromosomes.
mesh_terms: D000818:Animals; D002460:Cell Line; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics; D004262:DNA Restriction Enzymes; D005164:Factor IX / Q000235:genetics*; D005260:Female; D006801:Humans; D051379:Mice; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D014960:X Chromosome / Q000648:ultrastructure*
chemical_list: D005164:Factor IX; D004247:DNA; D004262:DNA Restriction Enzymes