[Prevention of complications following abdominal surgical urologic interventions by plasma protein substitutes].
A prospective randomised trial in 94 patients undergoing urological abdominal surgery has been carried out to evaluate the effect of postoperatively administered plasma proteins. A significant difference between the treatment group and the control group has been found in the incidence of bronchopulmonary complications. This may be due to the substitution of Alpha-1 antitrypsin as could be shown by determination of the activity of Alpha-1 antitrypsin levels. A positive trend but no significant differences could be demonstrated for wound healing and the need of antibiotics postoperatively.
D000005:Abdomen / Q000601:surgery*; D001798:Blood Proteins / Q000627:therapeutic use*; D001996:Bronchopneumonia / Q000517:prevention & control; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011183:Postoperative Complications / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000517:prevention & control; D014547:Urinary Diversion; D014945:Wound Healing / Q000187:drug effects; D019896:alpha 1-Antitrypsin Deficiency
D001798:Blood Proteins
Komplikationsprophylaxe nach abdominalchirurgisch-urologischen Eingriffen durch Plasmaproteinsubstitution.