[Effect of MEA on the degradation of thermally-damaged DNA in gamma-irradiated bacterial cells].
It was shown that the radioprotective action of beta-mercaptoethylamine on gamma-irradiated Bacillus stearothermophilus, with regard to survival and diminution of DNA breaks, depended upon the temperature of incubation and the presence of thermal lesions in DNA. beta-Mercaptoethylamine decreased the number of both alkali-labile sites and true single-strand DNA breaks in cells of Bacillus stearothermophilus. beta-Mercaptoethylamine decreased the number of alkali--labile sites and true single-strand breaks in DNA of Escherichia coli cells heated at 52 degrees C.
D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D002588:Cesium Radioisotopes; D004269:DNA, Bacterial / Q000528:radiation effects*; D004926:Escherichia coli / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D001411:Geobacillus stearothermophilus / Q000187:drug effects / Q000528:radiation effects; D006358:Hot Temperature; D008624:Mercaptoethylamines / Q000494:pharmacology*; D011837:Radiation-Protective Agents
D002588:Cesium Radioisotopes; D004269:DNA, Bacterial; D008624:Mercaptoethylamines; D011837:Radiation-Protective Agents
Vliianie MEA na degradatsiiu DNK, soderzhashchuiu termopovrezhdeniia, v gamma-obluchennykh kletkakh bakteriĭ.