Topical glucocorticosteroids.
A review of topical glucocorticosteroids is presented. Included is a discussion of the pharmacology of modern hydrocortisone derivatives and their vehicles, mechanisms of action with respect to skin and host inflammatory response and potential side effects of treatment. Guidelines for therapy and selection of appropriate therapeutic agents are also given.
D000287:Administration, Topical; D000375:Aging; D000893:Anti-Inflammatory Agents / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D001665:Binding Sites; D001682:Biological Availability; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D008940:Mitotic Index / Q000187:drug effects; D014677:Pharmaceutical Vehicles; D011955:Receptors, Drug; D012869:Skin Absorption / Q000187:drug effects; D012871:Skin Diseases / Q000188:drug therapy; D014662:Vasoconstrictor Agents
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D014677:Pharmaceutical Vehicles; D011955:Receptors, Drug; D014662:Vasoconstrictor Agents; D006854:Hydrocortisone