title: [IPAD-DTCP: study of the tolerability and serum antipoliomyelitic efficacy in a maternal-child health center at Pikine (Dakar)].
abstract: A study of the tolerance and potency of a quadruple vaccine adsorbed on calcium phosphate was carried out in Senegal. After a follow up of four months the local tolerance was better when the vaccine was inoculated by intramuscular injection. A high level of passively acquired antibodies was found for the three subtypes of polioviruses and seemed to delay the immunological reaction. 90%, 96% and 92% of the total group of children involved in this study had a positive reaction.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D004168:Diphtheria Toxoid / Q000008:administration & dosage*; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008430:Maternal-Child Health Centers; D010567:Pertussis Vaccine / Q000008:administration & dosage*; D017955:Poliovirus / Q000276:immunology*; D011054:Poliovirus Vaccine, Inactivated / Q000008:administration & dosage*; D012675:Senegal; D013745:Tetanus Toxoid / Q000008:administration & dosage*
chemical_list: D000914:Antibodies, Viral; D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D010567:Pertussis Vaccine; D011054:Poliovirus Vaccine, Inactivated; D013745:Tetanus Toxoid
vernacular_title: IPAD DTCP: étude de tolérance et d'éfficacité serologique antipoliomyélitique dans un centre de P.M.I. de Pikine (Dakar).