title: Genetic structure and population history of Ireland: a comparison of blood group and anthropometric analyses.
abstract: Population structure and history may be studied on a local or a regional level. This paper examines the regional population structure of the Republic of Ireland and Northern Ireland with respect to population history and demographic processes. Blood-group and anthropometric data obtained from the literature are analysed. The blood-group data consist of ABO and Rhesus gene frequencies for 32 counties and the Aran Islands. Anthropometric data consist of summary statistics for 15 variables collected from 19 regions. The degree and pattern of population differentiation is assessed using new methods of population-structure analysis. Both blood group and anthropometric analyses show a west-east division of populations corresponding to the known history of inhabitation of Ireland, where successive waves of immigrants pushed earlier populations further west. In both analyses there were two deviations to this basic pattern: the Aran Islands and the midlands. In both cases, alternative historical explanations are examined. The genetic relationship of the Aran Islands to the rest of Ireland and England appears to be due to English admixture following the garrisoning of soldiers several centuries ago. The genetic position of the midlands is more complex, but suggests the effects of early Viking inhabitation. These findings are related to studies of the local, rather than regional, population structure of Ireland.
mesh_terms: D000886:Anthropometry; D001789:Blood Group Antigens / Q000235:genetics*; D003710:Demography; D004641:Emigration and Immigration / Q000266:history; D005788:Gene Pool; D005828:Genetics, Population; D049669:History, 16th Century; D049670:History, 17th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049691:History, Medieval; D006801:Humans; D007494:Ireland; D009660:Northern Ireland; D011157:Population Dynamics
chemical_list: D001789:Blood Group Antigens