Immunological aspects in Plasmodium falciparum infection.
Patients with P. falciparum infection were shown to have circulating immune complexes in their sera detected by the inhibition of IgG-coated latex agglutination with RF factor and by the EAC rosette inhibition test. Low numbers of T cells and high numbers of B cells which contain immunoglobulins were demonstrated. T-cell depletion may be caused by antibody to T-lymphocytes being present in the sera of these patients.
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D000936:Antigen-Antibody Complex / Q000032:analysis; D006801:Humans; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology*; D008288:Malaria / Q000276:immunology*; D008875:Middle Aged; D010963:Plasmodium falciparum; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D000936:Antigen-Antibody Complex; D011947:Receptors, Antigen, B-Cell