title: Nitrogen metabolism of ruminant animals: historical perspective, current understanding and future implications.
abstract: Nitrogen metabolism of ruminant animals has been the subject of thousands of research publications. Study of ruminal and intestinal function continues. The quantitative and qualitative importance of ruminal microbes as a source of protein have become apparent in many trials, and factors controlling microbial protein synthesis or growth of microbes as well as ruminal degradation of dietary protein have been explored. Information on the supply side of the protein ledger (ruminal synthesis, bypass or escape of dietary protein; intestinal digestion) exceeds current knowledge of quantitative needs for amino acids. Descriptive models of N metabolism have evolved that amalgamate current concepts. With future amendments, these systems should prove useful in diet formulation to more fully utilize ruminal fermentation and increase productive efficiency of ruminant animals. Expanding knowledge of ruminal N metabolism will permit greater control and manipulation of the processes of ruminal fermentation and postruminal digestion.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D000829:Animals, Domestic / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism; D001426:Bacterial Proteins / Q000096:biosynthesis; D005503:Food Additives; D005544:Forecasting; D007408:Intestinal Absorption; D008961:Models, Structural; D009584:Nitrogen / Q000378:metabolism*; D009751:Nutritional Requirements; D009753:Nutritive Value; D011489:Protein Denaturation; D012417:Rumen / Q000378:metabolism* / Q000382:microbiology
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D005503:Food Additives; D000641:Ammonia; D009584:Nitrogen