Investigation of the beta-lactamase activity of Prototheca zopfii.
A total of 52 strains of Prototheca zopfii were studied with a series of beta-lactam compounds in order to test possible existence of beta-lactamase capable of inactivating these compounds. The method used was based on the iodimetric technique. Results showed the existence of beta-lactamase which worked in different degrees depending on the beta-lactam compounds.
D000560:Amdinocillin / Q000378:metabolism; D000667:Ampicillin / Q000031:analogs & derivatives / Q000378:metabolism; D003023:Cloxacillin / Q000378:metabolism; D008802:Mezlocillin / Q000378:metabolism; D010403:Penicillin Resistance; D010406:Penicillins / Q000378:metabolism* / Q000494:pharmacology; D011525:Prototheca / Q000187:drug effects / Q000201:enzymology*; D001618:beta-Lactamases / Q000378:metabolism*
D010406:Penicillins; D000667:Ampicillin; D001618:beta-Lactamases; C005195:methampicillin; D003023:Cloxacillin; D008802:Mezlocillin; D000560:Amdinocillin