title: [Experience with the Hickman catheter in bone marrow transplantation and intensive cytostatic chemotherapy].
abstract: Long-Term indwelling right atrial (Hickman) catheters were placed in 37 patients undergoing bone marrow transplantation or intensive chemotherapy for acute leukemia and other malignancies. Blood sampling, application of blood products or intravenous drugs and parenteral nutrition were impressively facilitated. Parents were easily trained for catheter care at home. The median duration of function has been 85 (2-312) days. 7 catheters had to be changed because of dislocation - especially in smaller children - or fluid leakage. In 6 severely neutropenic patients bacteremia was observed which resolved without catheter removal. The cause of death in 9 children with functioning catheter was due to the underlying disease (graft rejection, relapse). The use of Hickman-catheters improved venous access and supportive care in children with acute leukemia or other malignancies at an acceptable complication rate.
mesh_terms: D000741:Anemia, Aplastic / Q000628:therapy; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002404:Catheterization / Q000295:instrumentation*; D002408:Catheters, Indwelling; D002648:Child; D002675:Child, Preschool; D006325:Heart Atria; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000628:therapy; D008297:Male; D013997:Time Factors; D014683:Vena Cava, Superior
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Erfahrungen mit dem Hickman-Katheter bei Knochenmarkstransplantation und intensiver zytostatischer Chemotherapie.