A case of familial Mediterranean fever with cutaneous vasculitis and immune complex nephritis: light, electron, and immunofluorescent study of renal biopsy.
A 29-year-old patient suffering from familial Mediterranean fever developed severe myalgia and hematuria. Skin biopsy showed vasculitis. The kidney biopsy revealed diffuse proliferative and exudative glomerulonephritis. On immunofluorescent examination, IgM deposits accompanied by C3 were found in coarse granular peripheral distribution. Electron microscopy revealed glomerular subepithelial deposits. Familial Mediterranean fever with vasculitis and immune complex nephritis is discussed.
D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001158:Arteries / Q000473:pathology; D010505:Familial Mediterranean Fever / Q000150:complications / Q000473:pathology*; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000150:complications / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007678:Kidney Glomerulus / Q000648:ultrastructure; D008297:Male; D014657:Vasculitis / Q000150:complications / Q000473:pathology*
D000936:Antigen-Antibody Complex; D007075:Immunoglobulin M