title: [Microbiological studies before and after endoscopic papillotomy (EPT)].
abstract: A microbiological check-up was made on 17 patients with choledocholithiasis while they were undergoing EPT and control ERCP. The endoscopes were contaminated in 56% of the 34 procedures. In 9% of the interventions there were indications that mouth flora had been transferred to the duodeno-biliary region. Bacteriaemia occurred in 3 (17%) patients in connection with EPT. After a mean of four months following EPT, the colony count and the number of germs in the duodenal and biliary juice tended to increase; bacteria of the Klebsiella-Enterobacter-Serratia group became dominant. More than 80% of the bile and blood isolates were sensitive to cefotaxime, cefamandole and co-trimoxazole. To minimize the risk of infection following EPT and ERCP, repeated controls of the disinfection of the endoscopes and periendoscopic antibiotic prophylaxis are suggested.
mesh_terms: D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000209:etiology; D001646:Bile / Q000382:microbiology*; D002176:Candida albicans / Q000302:isolation & purification; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects; D004386:Duodenum / Q000382:microbiology*; D004724:Endoscopy / Q000009:adverse effects*; D004755:Enterobacteriaceae / Q000187:drug effects / Q000302:isolation & purification; D005260:Female; D042882:Gallstones / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018805:Sepsis / Q000209:etiology; D013210:Staphylococcus / Q000302:isolation & purification; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Mikrobiologische Untersuchungen vor und nach endoskopischer Papillotomie (EPT).