title: [Systemic complications of tumors].
abstract: Tumours may give rise to systemic complications, among others by the release of specific substances. The accompanying symptoms are referred to as paraneoplastic syndromes. These complications have a marked effect on the course run by the disease. A number of common syndromes which are easy to diagnose, are discussed in a survey of the literature, namely: cachexia, anorexia, fever, hypercalcaemia, hypoglycaemia, anaemia and coagulation defects. Attention is paid to the occurrence of the syndromes in man and dogs, the relationship with specific forms of tumour, the pathogenesis and some forms of possible therapy.
mesh_terms: D000740:Anemia / Q000503:physiopathology; D000818:Animals; D000855:Anorexia / Q000503:physiopathology; D001778:Blood Coagulation Disorders / Q000503:physiopathology; D001853:Bone Marrow / Q000503:physiopathology; D002100:Cachexia / Q000503:physiopathology; D005334:Fever / Q000503:physiopathology; D005943:Gluconeogenesis; D005947:Glucose / Q000378:metabolism; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D006934:Hypercalcemia / Q000503:physiopathology; D007003:Hypoglycemia / Q000503:physiopathology; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines / Q000502:physiology; D008247:Lysosomes / Q000201:enzymology; D010257:Paraneoplastic Syndromes / Q000503:physiopathology* / Q000662:veterinary; D010281:Parathyroid Hormone / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology; D011749:Pyrogens / Q000096:biosynthesis
chemical_list: D006133:Growth Substances; D007328:Insulin; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D010281:Parathyroid Hormone; D011453:Prostaglandins; D011749:Pyrogens; C010320:renotropins; C008718:osteoclast activating factor; D005947:Glucose
vernacular_title: Systemische complicaties van tumoren.