Carcinoma of the adrenal cortex causing primary hyperaldosteronism. A case report and review of the literature.
A male patient presenting with primary hyperaldosteronism after a three-year delay, was found to have an aldosterone producing adrenocortical carcinoma. Evidence is presented that aldosterone was the only steroid produced in excess. Only six other patients with adrenocortical carcinoma and isolated primary hyperaldosteronism could be traced in the literature. The relation between histology and endocrine functions of the tumor cells is discussed.
D000306:Adrenal Cortex Neoplasms / Q000098:blood supply / Q000378:metabolism* / Q000473:pathology; D000328:Adult; D000450:Aldosterone / Q000378:metabolism*; D000792:Angiography; D002277:Carcinoma / Q000098:blood supply / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006929:Hyperaldosteronism / Q000209:etiology*; D008297:Male; D009384:Paraneoplastic Endocrine Syndromes / Q000473:pathology*; D012083:Renin / Q000097:blood; D013997:Time Factors
D000450:Aldosterone; D012083:Renin; D006854:Hydrocortisone