A clinically useful capillary blood-sampling technique for rapid determination of therapeutic levels of theophylline.
Two blood-sampling techniques, capillary and venous, were compared using the EMIT method. No difference was found in reproducibility. However, persistent positive bias of 0.628 micrograms/ml (p less than 0.01) was noted with the capillary sampling method. Any hemolysis that occurred in the capillary sampling technique did not significantly affect the assay.
D000293:Adolescent; D000328:Adult; D001800:Blood Specimen Collection; D002196:Capillaries; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008875:Middle Aged; D012044:Regression Analysis; D013806:Theophylline / Q000097:blood*
D013806:Theophylline