B-cell multilobated lymphoma.
A 59-year-old man was hospitalized for evaluation of cervical lymph node enlargement, and a diagnosis of a diffuse histiocytic lymphoma with B-cell markers was made. The unusual multilobated nature of the lymphoma cells is the subject of this study. The light and electron microscopic features are described and compared with those previously reported T-cell lymphomas which appear to have similar morphologic features. The importance of performing immunologic marker assays to determine T-cell or B-cell type and the limited predictive value of morphologic features in this regard are emphasized.
D001402:B-Lymphocytes; D002467:Cell Nucleus / Q000648:ultrastructure; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008297:Male; D008875:Middle Aged