Mutagenic detection of complex environmental mixtures using the Salmonella/arabinose-resistant assay system.
The mutagenic sensitivity of SV50, the R-factor plasmid containing tester, of the Salmonella/arabinose-resistant assay system has been evaluated with different environmental complex mixtures, including extracts of airborne and diesel emission particles, oil-shale ash, nitrosated coal dust and water samples. The mutagenicities of all extracts were detectable with this assay. This study indicates that the arabinose-resistant assay with SV50 is useful for the detection of the mutagenic activity of environmental complex mixtures.
D000393:Air Pollutants / Q000494:pharmacology; D001089:Arabinose / Q000494:pharmacology*; D003031:Coal; D004781:Environmental Exposure; D009152:Mutagenicity Tests; D009153:Mutagens; D011815:R Factors; D012486:Salmonella typhimurium / Q000187:drug effects*; D014874:Water Pollutants, Chemical / Q000494:pharmacology
D000393:Air Pollutants; D003031:Coal; D009153:Mutagens; D014874:Water Pollutants, Chemical; D001089:Arabinose