title: Evaluation of nine teat dip formulations under experimental challenge to staphylococcus aureus and streptococcus agalactiae.
abstract: Nine postmilking teat dips were evaluated by an experimental challenge model against either Staphylococcus aureus, Streptococcus agalactiae, or both. Formulations containing .9 and .6% sodium hypochlorite, 1% sodium dichloro-s-triazene-trione, .55% chlorhexidine gluconate, and .35% povidone iodine reduced incidence of Staphylococcus aureus infections 56.8, 28.3, 75.9, 92.5, and 77.9%. Incidence of infections with Streptococcus agalactiae was reduced 48.1 and 63.2% by 1.7 and 1% sodium dichloro-s-triazene-trione formulations. The 1% chlorhexidine gluconate and .35% povidone iodine products reduced Streptococcus agalactiae infections 71.0 and 67.0%. Three experimental 1% iodophor formulations reduced Streptococcus agalactiae infections 28.9, 44.8, and 50.7%. The experimental challenge model was refined further and provided an efficient method to determine efficacy of postmilking teat dips.
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002417:Cattle; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D004341:Drug Evaluation / Q000662:veterinary; D005260:Female; D007466:Iodophors / Q000494:pharmacology; D008321:Mammary Glands, Animal; D008414:Mastitis, Bovine / Q000517:prevention & control*; D011206:Povidone-Iodine / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013203:Staphylococcal Infections / Q000662:veterinary*; D013211:Staphylococcus aureus / Q000187:drug effects; D013290:Streptococcal Infections / Q000662:veterinary*; D013292:Streptococcus agalactiae / Q000187:drug effects; D014227:Triazines / Q000494:pharmacology
chemical_list: D004202:Disinfectants; D007466:Iodophors; D014227:Triazines; D011206:Povidone-Iodine; D012973:Sodium Hypochlorite; C010882:chlorhexidine gluconate; C011765:troclosene; D002710:Chlorhexidine