The effect of insulin insufficiency on plasma thyroid hormones and some metabolic constituents in Pacific hagfish, Eptatretus stouti.
The effect of guinea pig anti-human insulin serum was studied in Pacific hagfish. The metabolic indicators of insulin insufficiency, such as elevation of plasma glucose, free fatty acids, and alpha-amino nitrogen levels were obtained at 72 and 120 hr after anti-insulin serum injection. Plasma triiodothyronine levels declined significantly 24 hr after anti-insulin serum administration. These findings supplement earlier data with the same species and suggest that the regulatory metabolic action of insulin and thyroid hormones are related in cyclostomes.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005399:Fishes / Q000097:blood*; D006196:Hagfishes / Q000097:blood*; D007328:Insulin / Q000172:deficiency*; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D013963:Thyroid Hormones; D014284:Triiodothyronine; D013974:Thyroxine