[Prevention of radiation-induced skin reactions in breast cancer].
In a controlled study O-(beta-Hydroxyethyl)-rutoside was administered to 31 patients suffering from breast tumor to evaluate the radio-protective effect of the drug. O-(beta-Hydroxyethyl)-rutoside was given intravenously daily before each radiation. Another group of 31 patients served as a control group. Besides subjective symptoms, skin irritations were controlled during the whole treatment period. The results are discussed.
D001943:Breast Neoplasms / Q000532:radiotherapy*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D006896:Hydroxyethylrutoside / Q000627:therapeutic use*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D012431:Rutin / Q000031:analogs & derivatives*; D012867:Skin / Q000187:drug effects / Q000528:radiation effects*
D006896:Hydroxyethylrutoside; D011837:Radiation-Protective Agents; D012431:Rutin
Zur Prophylaxe strahleninduzierter Hautreaktionen bei Patienten mit Mammatumoren.