T-cell growth factor production by adult, but not childhood. Acute lymphoblastic leukaemic cells.
The production of T-cell growth factor (TCGF) by acute lymphoblastic leukaemia (ALL) cells was determined in seven children and in three adults. A significant production of TCGF by adult, but not childhood, ALL cells was observed. The adult ALL cells were classified as "non-T-non-B" by surface marker analysis. It is suggested that TCGF production may not be confined to the cells of T-lineage.
D000208:Acute Disease; D000328:Adult; D002648:Child; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis*; D007945:Leukemia, Lymphoid / Q000378:metabolism*; D014411:Neoplastic Stem Cells / Q000378:metabolism; D010641:Phenotype
D007376:Interleukin-2