Experience with heat-killed antigens of L. longbeachae serogroups 1 and 2, and L. jordanis in the indirect fluorescence antibody test.
Sera from 1384 individuals were examined with a trivalent antigen composed of Legionella longbeachae serogroups 1 and 2 and L. jordanis. One hundred and twenty nine (9.3%) showed a reaction on screening. Thirty-six (2.6%) had a titre of greater than or equal to 64 with monovalent antigens. Ten (0.7%) had a high (greater than or equal to 256) or greater than or equal to fourfold rising titre of antibody to one or more antigens and six of these patients had a severe chest infection. No correlation was apparent between the presence of low level antibodies and disease.
D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006358:Hot Temperature; D006801:Humans; D007875:Legionella / Q000276:immunology*; D007877:Legionnaires' Disease / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012703:Serotyping
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial