title: Nettleship's two pedigrees of retinitis pigmentosa: a historical postscript.
abstract: Two pedigrees of retinitis pigmentosa, originally published by Nettleship, are presented with extracts from his private correspondence. Affected descendants from the two families have been traced, in one family extending the pedigree to nine affected generations, and in the other providing an instance of male-to-male transmission in a pedigree previously considered as being possibly X-linked.
mesh_terms: D000328:Adult; D000368:Aged; D004739:England; D005260:Female; D005799:Genes, Dominant; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012174:Retinitis Pigmentosa / Q000175:diagnosis / Q000235:genetics / Q000266:history*; D014794:Visual Fields