title: Effect of leprosy sera and foetal calf serum (FCS) on the T cell number of peripheral blood of leprosy patients.
abstract: Study was conducted in 24 cases of various types of leprosy and 10 healthy controls to find out the effect of various sera on the T cell count of peripheral blood lymphocytes by sheep erythrocyte rosetting method. The percentage of T lymphocytes in lepromatous and tuberculoid cases were significantly lower compared to that in normal healthy controls. All sera except FCS had a stimulatory effect on the number of T cells. The cells incubated for 24 hours in FCS did not show any stimulatory effect on the number of T cells, however, these FCS incubated cells showed a significant elevation in the number of T cells when further incubated in sera either from leprosy cases or from healthy subjects.
mesh_terms: D003470:Culture Media; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D007918:Leprosy / Q000276:immunology*; D007958:Leukocyte Count; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000166:cytology* / Q000276:immunology
chemical_list: D003470:Culture Media; D006133:Growth Substances