Efficacy of ampicillin and cefoxitin in the treatment of acute pelvic inflammatory disease. A comparative study.
Sixty patients with acute uncomplicated pelvic infection were treated with cefoxitin or ampicillin alone, the purpose being to show that a relatively cheap antimicrobial agent (ampicillin) could be used. The groups (30 patients in each) were clinically comparable (P greater than 0,01--Hotelling T-square test). In the first group 2 g ampicillin was administered intravenously on admission followed by 1 g intravenously 4-hourly, and in the second group 2 g cefoxitin was administered intravenously on admission followed by 1 g intravenously every 8 hours. A good response was obtained in both groups. On the basis of cost ampicillin would seem to be the treatment of choice in uncomplicated acute pelvic infection.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use*; D002440:Cefoxitin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy* / Q000382:microbiology; D011897:Random Allocation
D002440:Cefoxitin; D000667:Ampicillin