Distinct populations of class II molecules identified by monoclonal antibodies.
Binding inhibition and sequential immunoadsorption studies with two rat monoclonal antibodies have been used to demonstrate the existence of distinct populations (isotypes) of HLA-DR like (class II) molecules in human B lymphoma cell lysates. The structures of the molecules isolated by these two reagents have been compared by peptide 'mapping' and appear to be closely similar.
D000911:Antibodies, Monoclonal; D002051:Burkitt Lymphoma / Q000032:analysis; D002460:Cell Line; D004591:Electrophoresis, Polyacrylamide Gel; D000949:Histocompatibility Antigens Class II; D006801:Humans; D007163:Immunosorbent Techniques; D010455:Peptides / Q000032:analysis
D000911:Antibodies, Monoclonal; D000949:Histocompatibility Antigens Class II; D010455:Peptides