Highly selective vagotomy in duodenal ulceration and its complications. A 12-year review.
Highly selective vagotomy (HSV) was performed in 509 patients over 12 years for the surgical management of duodenal ulceration; 103 HSVs were carried out during the treatment of complications. The overall rate of ulcer recurrence was 7%, ranging from 10% in the first 4 years to 4% in the 6 years between 1975 and 1980. Highly selective vagotomy was performed in addition to closure of a perforated ulcer in 16 patients, with no recurrent ulcers or re-perforations. After the control of their bleeding duodenal ulcers, 25 patients had HSV with no rebleeding, although two patients had recurrent ulceration. Highly selective vagotomy was performed in 62 patients with stenosis in addition to dilatation (44) or duodenoplasty (18). There was a high incidence of recurrent ulceration (7) and stenosis (9) with digital dilatation while duodenoplasty gave better results with one recurrent stenosis and no recurrent ulceration. The authors conclude that HSV is justified by its late results as a definitive operation in chronic duodenal ulceration that allows preservation of the pylorus during surgery for complications.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004106:Dilatation / Q000379:methods; D004381:Duodenal Ulcer / Q000150:complications / Q000601:surgery*; D004386:Duodenum / Q000601:surgery; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000601:surgery; D011707:Pyloric Stenosis / Q000209:etiology / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D014628:Vagotomy / Q000009:adverse effects; D014629:Vagotomy, Proximal Gastric / Q000009:adverse effects