[Functioning of amino acid operons in Escherichia coli strains with an altered transcription and translation apparatus. II. The effect of mutations in genes coding ribosomal protein S5 and translation elongation factor G on the functioning of the ilv operon].
It has been shown in our previous study that mutations in genes relA, relC and rpsL result in the delay in Escherichia coli ilv operon derepression; the complete inhibition of derepression of the ilv operon is observed in the double mutants having alterations in rpsL and relA or relC genes. At present, some mutations occurring in the fus gene and altering the structure of the translational elongation G factor have been also found to delay derepression of E. coli ilv operon and complete inhibition in fusr and rel double mutants. Phenotypical ile and val auxotrophy is also detected in the double E. coli mutants with spectinomycin resistance mutation in rpsE gene coding for the structure of ribosomal S5 protein and mutations in relA or relC genes. The suggestion of participation of the ilv operon in regulation of other E. coli amino acid operons expression is discussed.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D029968:Escherichia coli Proteins; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D005815:Genetic Code; D009154:Mutation; D009876:Operon; D020653:Peptide Elongation Factor G; D010445:Peptide Elongation Factors / Q000235:genetics*; D014176:Protein Biosynthesis; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins / Q000235:genetics*; D014158:Transcription, Genetic
D000596:Amino Acids; D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D020653:Peptide Elongation Factor G; D010445:Peptide Elongation Factors; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins; C000717190:RpsI protein, E coli
Funktsionirovanie aminokislotnykh operonov u shtammov Escherichia coli s izmenennym apparatom transkriptsii i transliatsii. Soobshchenie II. Vliianie mutatsiĭ v genakh, kodiruiushchikh ribosomnyĭ belok S5 i faktor élongatsii transliatsii G, na funktsionirovanie ilv-operona.