Insulin kinetics in juvenile canine diabetics after glucose loading.
Glucose and insulin kinetics were studied in 4 juvenile canine diabetics and 6 healthy controls. Diabetic dogs were glucose intolerant with delayed insulin response after glucose challenge. Total insulin secretion was near that of the controls, but was inadequate when compared with corresponding plasma glucose concentrations.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000378:metabolism / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000378:metabolism*; D004285:Dogs; D005260:Female; D005947:Glucose / Q000494:pharmacology*; D005951:Glucose Tolerance Test / Q000662:veterinary; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D007333:Insulin Resistance; D000078790:Insulin Secretion; D007700:Kinetics; D008297:Male
D001786:Blood Glucose; D007328:Insulin; D005947:Glucose