title: [Haemophilus influenzae in respiratory pathology in adults].
abstract: Fifty patients were diagnosed bronchopulmonary Haemophilus infections, because of the production of a purulent sputum, containing at least 10(8) Haemophilus influenzae per ml. Among them were 36 males (average 52 years old) and 14 females (average 58 years old). There was a high percentage (64%) of smokers (over 30 packs/year) within this population, which also included heavy drinkers. The top incidence occurred in winter and spring. Most cases were related to an acute infection in a chronic bronchitis (26 cases). The other cases included 6 cancers, 6 sequelae of tuberculosis, 4 bronchiectasis, 4 asthma, and only 3 pulmonary consolidations. There usually was a low grade fever (only 8 cases reached or went beyond 38 degrees, while in 29 cases the body temperature kept below 38 degrees). The return to a normal temperature was obtained after 4 to 10 days of ampicillin therapy, with no fatal case within this series. The 50 strains were studied by the microbiology laboratory. The minimum inhibitory concentrations showed a peculiar response to ampicillin and erythromycin, and a less dramatic response to chloramphenicol and tetracyclin. Some strains were proved resistant (MIC over 4 micrograms per ml) to cefoxitine and cefamandole.
mesh_terms: D000328:Adult; D001991:Bronchitis / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005602:France; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000453:epidemiology; D006193:Haemophilus influenzae; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000175:diagnosis / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000453:epidemiology
vernacular_title: Haemophilus influenzae en pathologie respiratoire chez l'adulte.