Note on the stability of mefloquine hydrochloride in aqueous solution.
Using Desjardins' technique for the testing of antimalarials against Plasmodium falciparum in vitro, a 4-year-old solution of mefloquine in water (10(-3) mol/litre) was compared with a freshly prepared solution.The results showed that the two solutions had almost identical activity. There was no evidence for any instability of mefloquine in aqueous solution.
D000962:Antimalarials / Q000494:pharmacology*; D004355:Drug Stability; D004356:Drug Storage; D015767:Mefloquine; D010963:Plasmodium falciparum / Q000187:drug effects; D011804:Quinolines / Q000494:pharmacology*; D012996:Solutions; D013997:Time Factors
D000962:Antimalarials; D011804:Quinolines; D012996:Solutions; D015767:Mefloquine