Activation of the alternative complement pathway by lymphoblasts isolated from canine thymic lymphomas.
The ability of lymphocytes isolated from cases of canine thymic lymphomas to activate the alternative complement pathway has been studied. In a series of 14 thymic lymphomas 5 were found to activate the alternative pathway. This ability to activate was not abrograted by trypsinisation of the cells. It was found that normal canine thymic lymphocytes did not activate the alternative pathway.
D000818:Animals; D003167:Complement Activation; D003170:Complement Pathway, Alternative; D004283:Dog Diseases / Q000276:immunology; D004285:Dogs; D066298:In Vitro Techniques; D008223:Lymphoma / Q000276:immunology* / Q000662:veterinary; D013601:T-Lymphocytes / Q000276:immunology*; D013953:Thymus Neoplasms / Q000276:immunology* / Q000662:veterinary