[Analysis of viral capsid anti-antigen antibodies of the Epstein Barr virus in infectious mononucleosis. Comparative evaluation of a fluorescence method with classic methods].
708 sera were tested by a FA method for the detection of antibodies anti-viral capsid antigen in Epstein-Barr virus disorders to establish its effective value in infectious mononucleosis diagnosis. The arise of IgG class's antibody was not significative between recent infectious mononucleosis's patients and controls. Preliminary study of a test to research IgM anti-viral capsid antigen confirmed its value in infectious mononucleosis's diagnosis, but only in early stages of infection. At least, after evaluation of the results obtained by FA test for IgG-anti-viral capsid antigen in 200 blood donors the authors suggest the utilization of this method as screening in these people to avoid infectious mononucleosis transmission by blood transfusion in newborn children or in immunosuppressed patients.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000276:immunology*; D002213:Capsid / Q000276:immunology*; D036022:Capsid Proteins; D002648:Child; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis; D007244:Infectious Mononucleosis / Q000276:immunology*; D011933:Reagent Kits, Diagnostic
D000914:Antibodies, Viral; D000956:Antigens, Viral; D036022:Capsid Proteins; C041788:Epstein-Barr viral capsid antigen; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011933:Reagent Kits, Diagnostic
Ricerca degli anticorpi anti-antigene capsidico virale (VCA) del virus di Epstein-Barr nella diagnosi della monucleosi infettiva. Valutazione comparativa di una metodica in fluorescenza con le metodiche classiche.