Fulminating encephalopathy associated with Shigella flexneri infection.
Three cases of rapidly fatal encephalopathy associated with Shigella flexneri infection are reported. There was a lack of severe intestinal involvement and absence of metabolic derangement. In all 3 patients, areas of necrosis were present throughout the brains; and in one case pontine haemorrhages and demyelination were seen. This report supports the evidence of a particular neurotoxic effect in shigellosis.
D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D002648:Child; D004405:Dysentery, Bacillary / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D012763:Shigella flexneri