title: Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited.
abstract: Cholera vibrios produce a single polymeric protein that (i) causes hemagglutination; (ii) appears to participate in their attachment to gut epithelium; (iii) may mediate their detachment from gut epithelium; and (iv) is a protease that hydrolyzes fibronectin and mucin, cleaves lactoferrin, and nicks the A subunit of the choleragen-related heat-labile enterotoxin of Escherichia coli.
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D004768:Enterotoxins / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism*; D006389:Hemagglutinins, Viral; D006868:Hydrolysis; D007413:Intestinal Mucosa / Q000382:microbiology*; D007781:Lactoferrin / Q000378:metabolism; D037102:Lectins; D009077:Mucins / Q000378:metabolism; D010447:Peptide Hydrolases / Q000378:metabolism; D011817:Rabbits; D013379:Substrate Specificity; D014734:Vibrio cholerae / Q000201:enzymology*
chemical_list: D004768:Enterotoxins; D005353:Fibronectins; D006389:Hemagglutinins, Viral; D037102:Lectins; D009077:Mucins; D010447:Peptide Hydrolases; D007781:Lactoferrin