Intramuscular lorazepam. A double-blind comparison with diazepam and placebo.
In this double-blind, placebo-controlled study, 24 anxiety neurotic patients were randomly assigned equally into the intramuscular placebo, lorazepam or diazepam groups. The results indicated that lorazepam was as effective as diazepam in overall efficacy and was superior to diazepam in certain cluster scores including the Obsessive Compulsive Phobic Cluser of the Wittenborn Psychiatric Rating Scale.
D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008140:Lorazepam / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012894:Sleep Stages; D012893:Sleep Wake Disorders / Q000139:chemically induced
D008140:Lorazepam; D003975:Diazepam