title: The constancy of parent-offspring similarity of total cholesterol throughout childhood and early adult life. The Lipid Research Clinics Program Prevalence Study.
abstract: In a cross-sectional study of 11,409 white parent-offspring pairs in five North American populations we examined the effect of age of the offspring on parent-offspring total cholesterol correlations. In general there were no differences in correlations by age of the offspring for the four types (by gender) of parent-offspring pairs. This was true within each of the five populations and for the average of all populations combined. For offspring from less than 2-29 years of age, these average age-specific correlations ranged from 0.17 to 0.42. Despite the considerable physiologic and environmental changes which influence cholesterol levels from birth to early adulthood, the strength of parent-offspring similarity shows no consistent pattern of change.
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood / Q000235:genetics*; D003430:Cross-Sectional Studies; D003625:Data Collection; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario; D012737:Sex Factors; D014481:United States
chemical_list: D002784:Cholesterol