title: Survey of sickle cell disease in the Netherlands.
abstract: Through a questionnaire data were collected from 116 patients with sickle cell disease (SCD) in the Netherlands, about two thirds of all the patients with SCD in the country. Sixty-four percent of the patients are of Surinamese origin, 14% come from the Netherlands Antilles, 11% come from Turkey, and 11% from elsewhere. Two thirds of the patients live in Amsterdam and Rotterdam. Sixty-seven were children and 49 were adults. Sickle cell anaemia (SS disease) was found in 74, sickle cell beta thalassaemia (S beta thal) in 18, and sickle cell haemoglobin C(SC)-disease in 24 patients. Clinical features and treatment are discussed and the data are compared with the results of similar studies in other European countries.
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000453:epidemiology* / Q000235:genetics; D002648:Child; D003430:Cross-Sectional Studies; D005006:Ethnicity; D005260:Female; D005838:Genotype; D006450:Hemoglobin SC Disease / Q000453:epidemiology; D006451:Hemoglobin, Sickle / Q000235:genetics; D006452:Hemoglobinometry; D006801:Humans; D008297:Male; D009426:Netherlands; D012805:Sickle Cell Trait / Q000453:epidemiology* / Q000235:genetics; D013789:Thalassemia / Q000453:epidemiology / Q000235:genetics
chemical_list: D006451:Hemoglobin, Sickle