title: [Prostacyclin therapy in EPH gestosis (preliminary report)].
abstract: EPH-gestosis is still today one of the most dangerous complications of pregnancy, threatening both, maternal and fetal life. Until now only symptomatic treatment was possible. A new mode of treatment of EPH-gestosis may evolve from the use of prostacyclin, a potent vasodilator and inhibitor of platelet aggregation. We tried prostacyclin therapy in three patients with severe gestosis. The results of prostacyclin infusion on this condition, the pregnancy, the fetus, the placenta and the morphology of the umbilical artery are discussed.
mesh_terms: D000328:Adult; D004078:Dihydralazine / Q000627:therapeutic use; D011464:Epoprostenol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D011225:Pre-Eclampsia / Q000188:drug therapy*; D011247:Pregnancy; D011453:Prostaglandins / Q000627:therapeutic use*
chemical_list: D011453:Prostaglandins; D011464:Epoprostenol; D004078:Dihydralazine
vernacular_title: Prostazyklintherapie der EPH-Gestose (Vorläufige Mitteilung).