[Morphological changes after large-field irradiation of dogs and autologous bone marrow transplantation].
The effect of an automyelotransplant taken from a nonirradiated area of bone marrow has been studied after large fields irradiation in dogs. Certain changes occurring in the hemopoietic organs and in some other vitally important organs have been revealed. The automyelotransplantation contributes to a quicker repopulation of the bone marrow and stimulates lymphoid hemopoiesis in the spleen; that plays a positive role in overcoming the bone marrow syndrome at radiation illness. In other organs (gastrointestinal tract, kidneys, lungs, heart) given various doses of irradiation, in the control and test (with automyelotransplantation) groups similar morphological changes have been revealed.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D016026:Bone Marrow Transplantation; D002452:Cell Count; D004285:Dogs; D005260:Female; D006410:Hematopoiesis / Q000528:radiation effects*; D008297:Male; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000473:pathology* / Q000628:therapy; D013154:Spleen / Q000473:pathology; D014182:Transplantation, Autologous
Morfologicheskie izmeneniia pri krupnopol'nom obluchenii sobak i vozdeĭstvii automielotransplantatsii.