title: [Anesthesia with flunitrazepam/fentanyl in the severe coronary patient. Hemodynamic study].
abstract: Twenty three patients on class 3 or 4 NYHA were anesthetized with flunitrazepam 30 micrograms/kg. fentanyl 20 micrograms/kg, N2O for coronary bypass surgery. Hemodynamics data before and after induction reveal a 30% fall of cardiac index with stability of systolic vascular resistance. This higher value refer to literature on flunitrazepam. The clinical association with N2O and fentanyl can explain negatively inotropic effect. The bad ventricular function of this patients is probably the cause of a underestimate vascular filling.
mesh_terms: D000368:Aged; D000758:Anesthesia; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D005283:Fentanyl; D005445:Flunitrazepam; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008875:Middle Aged; D011229:Preanesthetic Medication / Q000379:methods
chemical_list: D006993:Hypnotics and Sedatives; D005445:Flunitrazepam; D005283:Fentanyl
vernacular_title: Anesthésie par flunitrazépam/fentanyl chez le coronarien sévère. Etude hémodynamique.