The isolated C3 in the 'vascular pole' in patients with primary haematuria.
Among sixty-four patients with primary haematuria, immunofluorescence methods revealed seven cases (11%) with isolated C3 deposits in the 'vascular pole'. Serum complement were normal and the follow-up after 20-41 months indicate a benign course. In patients with C3 deposits in the 'vascular pole' light microscopy was normal. We never observed C3 deposits in specimens of normal kidney which were processed by the same methods using mono-specific antisera confirmed by immunoelectrophoresis. This entity defined by immunofluorescence methods, can be called 'vascular pole disease'.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002196:Capillaries / Q000276:immunology; D002648:Child; D003176:Complement C3 / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006417:Hematuria / Q000276:immunology*; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D003176:Complement C3