title: Clastogenic and physiological response of chromosomes to nine pesticides in the Vicia faba in vivo root tip assay system.
abstract: 9 common pesticides were assayed for clastogenic and physiological activity using Vicia faba as a eukaryotic, whole-organism, test system. The compounds tested included the insecticides acephate, demeton, monocrotophos, parathion-methyl, and trichlorfon; the fungicides captan and folpet; and the herbicides bromacil and simazine. The chemicals have been grouped according to relative genotoxicity (strongly positive: demeton, parathion-methyl; positive: folpet, acephate, monocrotophos, captan; weakly positive: bromacil, trichlorfon, simazine). The results were compared with those reported from other assay systems.
mesh_terms: D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects* / Q000502:physiology; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D008223:Lymphoma / Q000503:physiopathology; D051379:Mice; D008940:Mitotic Index; D009152:Mutagenicity Tests; D009153:Mutagens; D009154:Mutation; D010053:Ovary; D010575:Pesticides / Q000633:toxicity*; D010944:Plants / Q000187:drug effects* / Q000235:genetics; D012486:Salmonella typhimurium / Q000187:drug effects; D012854:Sister Chromatid Exchange / Q000187:drug effects
chemical_list: D009153:Mutagens; D010575:Pesticides