Cyclosporin A treatment for chronic uveitis associated with retinitis.
A chronic bilateral non-granulomatous uveitis triggered by a chlamydial infection developed in a patient with HLA-B 27. Cyclosporin A was administered as an ultimate remedy. It had a rapid curative effect against the inflammation. Probable cytomegalovirus (CMV) retinitis, however, was observed 2 months after the onset of this treatment. Retinitis healed after discontinuation of Cyclosporin A therapy.
D000328:Adult; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000276:immunology; D003524:Cyclosporins / Q000627:therapeutic use*; D005451:Fluorescein Angiography; D006680:HLA Antigens; D015796:HLA-B27 Antigen; D006801:Humans; D008297:Male; D012173:Retinitis / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D014605:Uveitis / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D014792:Visual Acuity
D003524:Cyclosporins; D006680:HLA Antigens; D015796:HLA-B27 Antigen