title: [Multicenter study of the in vitro antibacterial activity of ceftazidime on gram-negative bacilli].
abstract: This work reports a multicenter study of antibacterial activity of ceftazidime, a new third generation cephalosporin, on hospital Gram negative rods. Enterobacteriaceae are very sensitive to ceftazidime with a maximum number of strains inhibited by 1 microgram/ml or less (modal MIC 0, 125 microgram/ml); some resistant strains are observed, particularly among Enterobacter and Citrobacter. Activity of ceftazidime on Pseudomonas aeruginosa is superior to other third generation cephalosporins; modal MIC is 1 microgram/ml and 88% of the strains are inhibited by 4 microgram/ml or less. Acinetobacter are less sensitive to ceftazidime, with a modal MIC of 8 microgram/ml.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000382:microbiology; D002442:Ceftazidime; D002511:Cephalosporins / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D002511:Cephalosporins; D002442:Ceftazidime
vernacular_title: Etude multicentrique de l'activité antibactérienne in vitro de la ceftazidime sur les bacilles gram négatifs.