Paroxysmal cold hemoglobinuria in a patient with Klebsiella pneumonia.
A case of paroxysmal cold hemoglobinuria (PCH) occurring in a patient with Klebsiella pneumonia is described. The first sign of PCH in the patient was erythrophagocytosis. The Donath-Landsteiner (D-L) antibody exhibited anti-P specificity both serologically and biochemically. The appearance of D-L antibody during fulminating Klebsiella pneumonia strongly suggests their causal relationship.
D001996:Bronchopneumonia / Q000150:complications*; D006457:Hemoglobinuria, Paroxysmal / Q000097:blood / Q000150:complications* / Q000628:therapy; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis; D007710:Klebsiella Infections / Q000150:complications*; D007711:Klebsiella pneumoniae; D008297:Male; D008875:Middle Aged; D010127:P Blood-Group System / Q000276:immunology; D013696:Temperature; D065227:Transfusion Reaction
D007518:Isoantibodies; D010127:P Blood-Group System