[Migration of hepatic macrophages after cyclophosphamide or whole body irradiation].
The liver macrophages behaviour after cyclophosphamide or total-body irradiation (1000 rads - 60Co) has been studied in the mouse previously injected with colloidal carbon. In these conditions an early increase of carbon-laden macrophages in the central zone of the liver lobules has been observed. Carbon-containing mononuclear cells were also observed in the lumina of the hepatic collecting system. Possible implications of these findings are discussed; a migration of macrophages from the liver to elsewhere is suggested.
D000818:Animals; D002633:Chemotaxis / Q000187:drug effects / Q000528:radiation effects; D003520:Cyclophosphamide / Q000494:pharmacology*; D008099:Liver / Q000473:pathology*; D008264:Macrophages / Q000187:drug effects / Q000528:radiation effects; D008297:Male; D051379:Mice; D014916:Whole-Body Irradiation
D003520:Cyclophosphamide
Migrazione di macrofagi epatici dopo ciclofosfamide o panirradiazione.