[Biological properties of immunochemically pure tetanus antitoxin].
Immunochemically pure tetanus antitoxin obtained from enzyme-treated horse serum is less reactogenic and anaphylactogenic and possesses higher therapeutic properties than antitoxin purified by nonspecific physico-chemical methods and containing ballast antigens. Due to its increased persistence in the recipient's body, the immunochemically pure antitoxin induces passive immunity in considerably lower doses than the preparations purified by the method "Diaferm-3".
D000707:Anaphylaxis / Q000276:immunology; D000818:Animals; D000906:Antibodies / Q000032:analysis; D002850:Chromatography, Gel; D006385:Hemagglutination Inhibition Tests; D006736:Horses; D007106:Immune Sera / Q000032:analysis; D007116:Immunization, Passive; D007122:Immunoelectrophoresis; D007163:Immunosorbent Techniques; D051379:Mice; D011817:Rabbits; D013743:Tetanus Antitoxin / Q000276:immunology / Q000302:isolation & purification* / Q000627:therapeutic use
D000906:Antibodies; D007106:Immune Sera; D013743:Tetanus Antitoxin
Biologicheskie svoĭstva immunokhimicheski chistogo stolbniachnogo antitoksina.