[Biosynthesis of the acetylation coenzyme in albino rat liver in the initial period of acute radiation sickness].
Mature albino rats were exposed to gamma-rays in a sublethal dose. A decrease of 22-35%, 13-39% and 29-37% was observed in the incorporation of 14C-pantothenate, 4'-phosphopantetheine and CoA, respectively, into the extracted fraction of free vitamin. After the first hour of observation specific activity of CoA decreased by 33% and corresponded to a decrease in the activity of ATP: D-pantothenate-4'-phosphotransferase.
D000818:Animals; D003065:Coenzyme A / Q000096:biosynthesis*; D005720:Gamma Rays; D008099:Liver / Q000201:enzymology*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D013997:Time Factors; D014916:Whole-Body Irradiation
D003065:Coenzyme A
Biosintez kofermenta atsetilirovaniia v pecheni belykh krys v nachal'nyĭ period ostroĭ luchevoĭ bolezni.