[Morbidity of schistosomiasis mansoni in Brazil. Developmental study in an endemic area over a 10-year period].
Four cross sectional studies on morbidity of schistosomiasis mansoni were carried out respectively in 1973, 1974, 1979 and 1983 in the Village of Capitão Andrade, District of Itanhomi, State of Minas Gerais, Brazil, through clinical and fecal examination of the population. In addition a comparison was made of the dinamic and infection rate of the snails and the man-water contact between 1973-1974. The present study compares the prevalence of the human infection by S. mansoni and the evolutive pattern of the disease in the area from 1973 to 1983. Besides 190 persons infected with S. mansoni and 134 non-infected, were followed-up during this period. The infection rate was 60.8% among 1,234 persons examined in 1973, decreasing to 36.2% of the 1,269 examined in 1983. However, the intense migration of the population in the area and the specific treatment of 7% of persons by their own decision may be partially responsible for this reduction. Although there was a decrease of more than 50% in the mean egg output of S. mansoni, there was no change in the morbidity of the disease and in the proportion of the different clinical forms. The incidence of S. mansoni infection among 134 persons followed-up during the ten years was 40.3% (annual average of 4%), with 61.9% in males. The incidence of the clinical forms was 51.8% for type I (intestinal form), 38.9% for type II (hepatointestinal) and 9.3% for type III (hepatoesplenic). The clinical evolutive pattern of 190 patients followed-up during the mentioned period showed that 75.3% had no change, 12.1% deteriorated and 12.6% improved. Two thirds of those which improved (8.4%) had received specific treatment.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010270:Parasite Egg Count; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology
Morbidade da esquistossomose mansoni no Brasil. III. Estudo evolutivo em uma área endêmica no período de dez anos.