title: [Localization of the genes coding for GTP cyclohydrolase II and riboflavin synthase on the chromosome of Escherichia coli K-12].
abstract: A conjugation analysis of riboflavin-dependent mutants of Escherichia coli K-12 has been made by means of various F'-factors. It is shown that the GTP cyclohydrolase II gene is localized in the chromosome map site between 27 and 30 min; the riboflavin synthase gene--in the site between 56 and 59 min; and the gene in which mutation causes accumulation of 2,6-dioxy-5-amino-4-ribitylamino-pyrimidine--in the site limited by 61-65 min. So it may be concluded that riboflavin biosynthesis genes in the E. coli chromosome are not clustered.
mesh_terms: D000619:Aminohydrolases / Q000235:genetics*; D002874:Chromosome Mapping; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D006136:GTP Cyclohydrolase / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D005815:Genetic Code; D009876:Operon; D012256:Riboflavin / Q000096:biosynthesis / Q000235:genetics; D012258:Riboflavin Synthase / Q000235:genetics*; D014166:Transferases / Q000235:genetics*
chemical_list: D014166:Transferases; D012258:Riboflavin Synthase; D000619:Aminohydrolases; D006136:GTP Cyclohydrolase; D012256:Riboflavin
vernacular_title: Lokalizatsiia genov, kodiruiushchikh GTF-tsiklogidrolazu II i riboflavinsintazu na khromosome Escherichia coli K-12.