[Disorder of the repair of DNA double-stranded breaks in radiosensitive mutants of Saccharomyces cerevisiae yeasts].
DNA double-strand break repair and restoration of viability in X-irradiated diploid yeast cells homozygous for rad50, rad51, rad52, rad55 mutations were studies under conditions of keeping the cells in non-nutrient medium, after irradiation. All the cells were synchronized at the G1 stage of the cell cycle. In contrast to the wild-type yeast, this group of mutants are unable to repair DNA double-strand breaks and do not enhance viability, when kept in non-nutrient medium after irradiation.
D004260:DNA Repair / Q000528:radiation effects*; D004271:DNA, Fungal / Q000528:radiation effects*; D004171:Diploidy; D005838:Genotype; D009154:Mutation; D011836:Radiation Tolerance; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000528:radiation effects*
D004271:DNA, Fungal
Narushenie reparatsii dvunitevykh razryvov DNK u radiochuvstvitel'nykh mutantov drozhzheĭ Saccharomyces cerevisiae.