title: Effect of venom gland extracts of the South American brown spider, Loxosceles laeta, on in vitro protein synthesis.
abstract: There was no effect of the venom extract on incorporation of phenylalanine into protein from phenylalanyl-tRNA. In contrast, the esterification of amino acids with tRNA was inhibited by the venom extracts in a dose-dependent manner, with an apparent preservation of the covalent structure of aminoacyl-tRNA.
mesh_terms: D000818:Animals; D001180:Arthropod Venoms / Q000494:pharmacology*; D004926:Escherichia coli / Q000378:metabolism; D005088:Exocrine Glands / Q000032:analysis; D066298:In Vitro Techniques; D010649:Phenylalanine / Q000378:metabolism; D014176:Protein Biosynthesis; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism; D051381:Rats; D013111:Spider Venoms / Q000494:pharmacology*; D014020:Tissue Extracts / Q000494:pharmacology
chemical_list: D001180:Arthropod Venoms; D012346:RNA, Transfer, Amino Acyl; D013111:Spider Venoms; D014020:Tissue Extracts; D010649:Phenylalanine