Lymphocyte transformation rates of homosexual men in presence of seminal plasma.
The peripheral lymphocytes of eleven healthy homosexual men and six heterosexual males were used in microlymphocyte culture systems to compare their transformation rates in the presence of PHA-M. Two homosexual men were randomly selected from the group to investigate the influence of seminal plasma fractions on their lymphocytes. The seminal plasma fractions were obtained from heterosexual normozoospermic men. Seventy two percent of the homosexual T-cell responsiveness to PHA was inhibited compared with the lymphocytes of the heterosexual men. The lymphocytes of the homosexual male seem to be less sensitive for the inhibition components present in seminal plasma.
D000328:Adult; D002478:Cells, Cultured; D006716:Homosexuality; D006801:Humans; D008213:Lymphocyte Activation; D008297:Male; D010835:Phytohemagglutinins / Q000494:pharmacology; D012661:Semen / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D010835:Phytohemagglutinins