Primary immune responses to H-Y in BALB/c-H-2k mice.
Female mice of the H-2k haplotype have been thought not to reject primary grafts of male skin. However, most BALB/c-H-2k female mice bred in our colony rejected syngeneic male grafts. Graft rejection was sufficient to prime the mice for the subsequent generation of H-Y-specific cytotoxic T cells and delayed-type hypersensitivity responses.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D005260:Female; D006084:Graft Rejection; D006182:H-Y Antigen / Q000235:genetics*; D006789:Host vs Graft Reaction; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008817:Mice, Mutant Strains; D012867:Skin / Q000276:immunology; D016038:Skin Transplantation; D014185:Transplantation, Isogeneic
D006182:H-Y Antigen