title: [201Thallium single photon emission computer tomography (SPECT) in the functional evaluation of coronary stenosis changes. Results of a comparison of stress scintigraphic and coronary angiographic findings].
abstract: 201TI-Single-photon-emission computed tomography (SPECT) was employed in 57 patients immediately after exercise, followed by a redistribution analysis 3 hours later. 44 patients had coronary artery disease as documented by angiography (of these, 27 patients had an earlier myocardial infarction confirmed). 13 patients produced normal angiograms. 201TI-SPECT revealed a sensitivity of 93% and a specificity of 84%. Referring to a subdivision of the left ventricle into anterior and posterior walls, sensitivity in infarcted segments (96%) was significantly (p less than 0.01) higher than in non-infarcted segments (71%). No difference in sensitivities was found comparing anterior and posterior walls. Specificity of segmental analysis was 92%. Evaluation of segmental pattern (positive or negative redistribution) in old infarctions revealed persisting 201TI defects as frequent as the combination of persisting defects with surrounding redistribution. Non-infarcted segments showed sole redistribution in 89% of the cases. Left ventricular 201TI-SPECT improves the anatomical definition of defects in 201TI uptake. It enhances the functional evaluation of changes in regional perfusion subsequent to pathological coronary morphology.
mesh_terms: D002932:Cineangiography; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis; D011868:Radioisotopes; D013793:Thallium; D014055:Tomography, Emission-Computed / Q000379:methods*
chemical_list: D011868:Radioisotopes; D013793:Thallium
vernacular_title: Die 201Thallium-Single-Photon-Emissions-Computertomographie (SPECT) in der funktionellen Beurteilung koronarstenotischer Veränderungen. Ergebnisse des Vergleichs von belastungsszintigraphischen mit koronarangiographischen Befunden.