Bronchodilator effects of the H1 receptor antagonist--clemastine.
We investigated the specific H1 receptor antagonist, clemastine, in 15 children with asthma. In the respiratory unit, clemastine was an effective bronchodilator but in a clinical trial we could not show any significant benefit compared with placebo.
D000293:Adolescent; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002648:Child; D002974:Clemastine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D011759:Pyrrolidines / Q000627:therapeutic use*
D001993:Bronchodilator Agents; D011759:Pyrrolidines; D002974:Clemastine