[Reactions of the adreno-hypothalamo-hypophyseal system in rats chilled in a hypoxic-hypercapnic gaseous medium].
The rearrangement of the adrenal-hypothalamus-pituitary system of rats kept in a low-temperature hypoxic-hypercapnic atmosphere was investigated. Phasic changes of the system were detected, with their magnitude and sign depending on the exposure time. The central and peripheral components of the system developed specific relations. One of the peculiarities of the responses of the adrenal-hypophysis-pituitary system to the above exposure is a limited range of changes in the neuroendocrine activities due to a total reactivity decrease. This protects the neuroendocrine system from overstrain or involvement in overshooting reactions. It is assumed that this type of response of the adrenal-hypophysis-pituitary system is important to help understand mechanisms of the neuroendocrine regulation of the adaptive process developing in response to the combined effect.
D015062:11-Hydroxycorticosteroids / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D003080:Cold Temperature; D006935:Hypercapnia / Q000473:pathology / Q000503:physiopathology*; D007030:Hypothalamo-Hypophyseal System / Q000473:pathology / Q000503:physiopathology*; D000860:Hypoxia / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D009490:Neurosecretory Systems / Q000473:pathology; D010286:Paraventricular Hypothalamic Nucleus / Q000473:pathology; D010913:Pituitary-Adrenal System / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D013495:Supraoptic Nucleus / Q000473:pathology
D015062:11-Hydroxycorticosteroids; D000324:Adrenocorticotropic Hormone
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