Immunocytochemical localization of serotonin-like immunoreactivities in the ciliated epithelium of the frog palatine mucosa.
Immunocytochemical localization of serotonin (5-HT)-like immunoreactivities was studies in the ciliated epithelium of the frog palatine mucosa by the peroxidase anti-peroxidase (PAP) method. 5-HT-like immunoreactivity was found only in the small granular vesicles (100-150 nm in diameter) and not in any mature large secretory granules or in other cell organellae in the goblet cells. No 5-HT-like immunoreactivities were found in any other epithelial and secretory cells in the palatine epithelium. It appears therefore that 5-HT-like immunoreactive granular vesicles have certain physiological effects on the ciliary movement of the ciliated cells or in the goblet cells.
D000818:Animals; D002923:Cilia / Q000502:physiology; D004848:Epithelium / Q000276:immunology / Q000648:ultrastructure; D006651:Histocytochemistry; D007120:Immunochemistry; D008297:Male; D008854:Microscopy, Electron; D009061:Mouth Mucosa / Q000276:immunology* / Q000648:ultrastructure; D009068:Movement; D010159:Palate / Q000276:immunology* / Q000648:ultrastructure; D011892:Rana catesbeiana / Q000378:metabolism*; D012701:Serotonin / Q000276:immunology*
D012701:Serotonin