Is loxapine more effective than chlorpromazine in paranoid schizophrenia?
The authors compared loxapine with chlorpromazine in inpatients with paranoid schizophrenia and found no difference in clinical efficacy. Thus a previous finding, based on retrospective analyses, that loxapine was superior to other neuroleptics in the treatment of paranoid schizophrenia was not verified in this prospective study.
D000293:Adolescent; D000328:Adult; D002746:Chlorpromazine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003989:Dibenzoxazepines / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006760:Hospitalization; D006801:Humans; D008152:Loxapine / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012563:Schizophrenia, Paranoid / Q000188:drug therapy* / Q000523:psychology
D003989:Dibenzoxazepines; D008152:Loxapine; D002746:Chlorpromazine