Chlamydia and Reiter's syndrome.
The role of Chlamydia trachomatis in Reiter's syndrome (RS) is reviewed. Chlamydia is an obligate, intracellular parasite which can be isolated from urethral smears in 36% of patients with RS. Two separate surveys carried out on RS patients in France, in 1977-78 and in 1982-83 showed that antibodies to C. trachomatis could be detected by a microimmunofluorescence test in 55% and 64% of subjects, respectively, and this is significantly higher than the levels found in rheumatoid or healthy controls. Further studies are indicated to evaluate the role of Chlamydia in RS.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D016918:Arthritis, Reactive / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D002690:Chlamydia Infections / Q000150:complications* / Q000276:immunology; D002692:Chlamydia trachomatis / Q000276:immunology / Q000302:isolation & purification; D006680:HLA Antigens; D015796:HLA-B27 Antigen; D006801:Humans; D013577:Syndrome; D013582:Synovial Fluid / Q000276:immunology
D000907:Antibodies, Bacterial; D006680:HLA Antigens; D015796:HLA-B27 Antigen