Gamma scintigraphy using Tc-99m labeled antibody to human chorionic gonadotropin.
A case report is presented describing a 27-year-old woman with invasive trophoblastic hydatidiform mole metastatic to the lung. Gamma scintiscanning, using a polyclonal and monoclonal antibody specific to human chorionic gonadotropin, hCG, and labeled with Tc-99m, is described. The area of the primary lesion in the uterus was demonstrated with both antibodies tested without computer subtraction techniques; metastatic deposits in the lung were detected only with the aid of blood pool subtraction techniques.
D000328:Adult; D000906:Antibodies / Q000008:administration & dosage / Q000276:immunology; D006063:Chorionic Gonadotropin / Q000276:immunology*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D011247:Pregnancy; D011877:Radionuclide Imaging; D013382:Subtraction Technique; D013667:Technetium; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging*
D000906:Antibodies; D006063:Chorionic Gonadotropin; D013667:Technetium