Localized cicatricial pemphigoid (Brunsting-Perry). A transplantation experiment.
Normal skin was transplanted into a cicatricial plaque in a patient affected with localized, benign pemphigoid of the Brunsting-Perry type. Eight weeks later, the transplanted tissue was removed and found to have IgG at the basement membrane zone on immunofluorescence microscopy. Subepidermal bullae developed at the graft-donor site. Local factors and trauma may be important in the pathogenesis of this variant of cicatricial pemphigoid.
D000284:Administration, Oral; D001485:Basement Membrane / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000209:etiology / Q000473:pathology*; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*; D016038:Skin Transplantation
D007074:Immunoglobulin G; D011241:Prednisone