Orthostatic hypertension with nephroptosis and aortitis disease.
A 53-year-old woman with nephroptosis and aortitis disease was found also to have orthostatic hypertension. When standing, she had high renin levels and normal catecholamine values, with a reduced baroreflex sensitivity. This orthostatic hypertension largely may be due to an activation of the renin system caused by nephroptosis and partly due to a reduced baroreflex sensitivity caused by aortitis. Captopril and propranolol hydrochloride were effective for the treatment of hypertension.
D001025:Aortitis / Q000150:complications*; D002216:Captopril / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology*; D007668:Kidney / Q000002:abnormalities*; D008875:Middle Aged; D011187:Posture; D011311:Pressoreceptors / Q000503:physiopathology; D011433:Propranolol / Q000008:administration & dosage; D012083:Renin / Q000097:blood
D002216:Captopril; D011433:Propranolol; D012083:Renin