The deoxyuridine suppression test in severe anaemia following Plasmodium falciparum malaria.
Haematological studies in a group of Gambian children with severe anaemia due to Plasmodium falciparum malaria revealed marked dyserythropoietic changes in erythroblasts and evidence of increased ineffective erythropoiesis. In some cases, the bone marrow also showed a few giant metamyelocytes and ring sideroblasts. The results of deoxyuridine suppression tests indicated that these haematological disturbances were not a consequence of vitamin B12 or folate deficiency within marrow cells.
D000740:Anemia / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D001853:Bone Marrow / Q000378:metabolism; D002675:Child, Preschool; D004247:DNA / Q000096:biosynthesis; D003857:Deoxyuridine; D004920:Erythropoiesis; D005492:Folic Acid / Q000097:blood; D006801:Humans; D007223:Infant; D008288:Malaria / Q000097:blood / Q000150:complications*; D010963:Plasmodium falciparum; D014805:Vitamin B 12 / Q000097:blood
D004247:DNA; D005492:Folic Acid; D014805:Vitamin B 12; D003857:Deoxyuridine