The use of Healon in corneal transplant surgery with and without intraocular lenses.
Healon was used in penetrating keratoplasty in order to assess the effect on donor cornea. Forty patients were divided into four groups. In Group 1, there were 20 patients who underwent intracapsular cataract extraction, intraocular lens implantation, and penetrating keratoplasty. In Group 2, there were 10 patients who underwent intracapsular cataract extraction and corneal graft surgery. In Group 3, there were four patients with corneal dystrophy who underwent penetrating keratoplasty; and in Group 4, there were six patients with decompensated corneas who had intraocular lenses in situ and who underwent corneal replacement surgery. In each group, half of the patients randomly selected were treated with Healon, while the remaining patients served as controls and were treated with air/BSS. Healon treated recipients lost fewer endothelial cells and had thinner corneas than their control group counterparts. The intraocular pressure was slightly higher in the Healon group, but was easily controlled by proper medication. Healon was found to be beneficial to the patient and a safe adjunct in penetrating keratoplasty surgery.
D000368:Aged; D003315:Cornea / Q000187:drug effects; D016039:Corneal Transplantation; D004727:Endothelium / Q000187:drug effects; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007429:Intraocular Pressure / Q000187:drug effects; D007910:Lenses, Intraocular; D008875:Middle Aged; D014945:Wound Healing / Q000187:drug effects
D006820:Hyaluronic Acid