title: Acute leukemia in children. Model for the development of scientific methodology for clinical therapeutic research in cancer.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002452:Cell Count; D002455:Cell Division / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D006689:Hodgkin Disease / Q000188:drug therapy / Q000401:mortality; D006801:Humans; D007223:Infant; D007700:Kinetics; D007938:Leukemia / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D007939:Leukemia L1210 / Q000188:drug therapy; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000401:mortality; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000401:mortality; D008297:Male; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000401:mortality; D008727:Methotrexate / Q000008:administration & dosage; D051379:Mice; D008954:Models, Biological
chemical_list: D008727:Methotrexate