A purified polysaccharide isolated from Candida albicans induces antibody response in vitro by human peripheral blood lymphocytes and discriminates between sera from normal and Candida albicans-infected individuals.
A purified polysaccharide extracted from Candida albicans (MPPS), stimulates in vitro synthesis of specific antibodies by human peripheral blood lymphocytes. These antibodies can be detected by a sensitive enzyme-linked immunoassay. The same assay can be applied to the quantitation of anti-candida antibodies in serum. Statistically significant differences were found between sera of normal and candida-infected individuals.
D000328:Adult; D000908:Antibodies, Fungal / Q000302:isolation & purification; D000917:Antibody Formation / Q000187:drug effects*; D002176:Candida albicans / Q000276:immunology*; D002177:Candidiasis / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D008214:Lymphocytes / Q000276:immunology; D011134:Polysaccharides / Q000494:pharmacology*
D000908:Antibodies, Fungal; D011134:Polysaccharides