Heavy ion effects on yeast cells: reappearance of the oxygen effect with very high LET.
Survival of a diploid and a haploid wild type and a radiation-sensitive rad52-mutant was investigated after exposure to accelerated ions in the presence or absence of oxygen. Ar, Kr, Xe, Sm, Pb and U ions were used with specific energies between 0.3 and 12 MeV/u. The results demonstrate that the oxygen enhancement ratios (o.e.r.) do not only depend on LET or Z*2/beta 2 but even more so on ion specific energy. The o.e.r.s are always higher with greater E/m values pointing to the importance of delta-electron action.
D002470:Cell Survival / Q000528:radiation effects; D004171:Diploidy; D004735:Energy Transfer; D006238:Haploidy; D007477:Ions; D009154:Mutation; D010100:Oxygen / Q000502:physiology*; D010315:Particle Accelerators; D012441:Saccharomyces cerevisiae / Q000528:radiation effects*
D007477:Ions; D010100:Oxygen