Hypothalamic catecholamine biosynthesis and neuropeptides.
In conclusion, both steady state and non-steady state methods for investigating the turnover of central catecholamines can provide valuable information regarding the central control of neuroendocrine function. The system described here, utilizing HPLC with electrochemical detection, offers a relatively easy and reliable method for determining steady state catecholamine biosynthesis in the hypothalamus and other brain areas.
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004298:Dopamine / Q000096:biosynthesis*; D007033:Hypothalamus, Middle / Q000378:metabolism*; D007700:Kinetics; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009638:Norepinephrine / Q000096:biosynthesis*; D011865:Radioisotope Dilution Technique; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium; D014443:Tyrosine / Q000378:metabolism
D009419:Nerve Tissue Proteins; D014316:Tritium; D014443:Tyrosine; D004298:Dopamine; D009638:Norepinephrine