[Effect of ethmozine on kidney function].
Injection of ethmozine to rats (50 mg/kg subcutaneously) and to dogs (0,5 mg/kg intravenously) produced a substantial rise in diuresis, natriuresis and kaliuresis at the expense of the increased glomerular filtration rate and renal circulation. Injection of ethmozine (0.25-1.0 mg/min for 20 min) to the renal artery of dogs had no effect on the ipsilateral side. It is assumed that alterations in renal function induced by ethmozine injection are extrarenal in nature.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D003404:Creatinine / Q000652:urine; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D007668:Kidney / Q000187:drug effects*; D016293:Moricizine; D009318:Natriuresis / Q000187:drug effects; D010640:Phenothiazines / Q000494:pharmacology*; D011188:Potassium / Q000652:urine; D051381:Rats; D012079:Renal Circulation / Q000187:drug effects
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; D016293:Moricizine; D003404:Creatinine; D011188:Potassium
Vliianie etmozina na funktsiiu pochek.