[Peptides of the "middle molecule" group].
The "middle molecules", endotoxins of peptide nature appearing in biological fluids in several diseases, cause the disorder of many regulatory processes, suppress the functions of blood cells, affect the transport characteristics of cell membranes. The review covers different aspects of formation, structure and numerous biological effects of "middle molecules", including the molecular mechanism of their biological action.
D000595:Amino Acid Sequence; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D002850:Chromatography, Gel; D003094:Collagen / Q000378:metabolism; D004731:Endotoxins / Q000097:blood; D005342:Fibrinolysis; D006801:Humans; D008970:Molecular Weight; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides / Q000097:blood* / Q000502:physiology; D014118:Toxins, Biological / Q000097:blood*
D004731:Endotoxins; D010446:Peptide Fragments; D010455:Peptides; D014118:Toxins, Biological; C026865:uremia middle molecule toxins; D003094:Collagen
Peptidy gruppy "srednikh molekul".