title: Inheritance of intersex disorders.
abstract: Intersex disorders result from abnormalities of the sex chromosomes, gonads, internal and external genitalia, sex hormones and gender role. This article reviews the literature on intersex disorders, outlining the characteristics and mode of inheritance, if known, of each. For appropriate and effective management and counselling of patients and their families, physicians must have a good knowledge of the development of the genital tract and of the interaction between genetic sex and environmental influences.
mesh_terms: D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000172:deficiency; D000312:Adrenal Hyperplasia, Congenital / Q000235:genetics; D000728:Androgens / Q000235:genetics; D012734:Disorders of Sex Development / Q000235:genetics*; D005260:Female; D005837:Genitalia, Male / Q000002:abnormalities; D006059:Gonadal Dysgenesis / Q000235:genetics; D006801:Humans; D008297:Male; D009095:Mullerian Ducts; D012729:Sex Chromosome Aberrations / Q000235:genetics
chemical_list: D000728:Androgens; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase