title: [Synthesis and anti-aggregating activity of 11-deoxyprostacyclin].
abstract: 11-Deoxyprostacyclin was prepared in three stages starting from the 11-deoxyprostaglandin F2 alpha methyl ester. 11-Deoxyanalog showed 0,9% of natural prostacyclin potency in inhibition of platelet aggregation.
mesh_terms: D000818:Animals; D011464:Epoprostenol / Q000138:chemical synthesis* / Q000494:pharmacology / Q000031:analogs & derivatives; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
chemical_list: C042760:11-desoxyprostacyclin; D011464:Epoprostenol
vernacular_title: Sintez i antiagregatsionnaia aktivnost' 11=dezoksiprostatsiklina.