Bronchoprovocation in children and variability of pulmonary function tests--1964.
Asthmatic symptoms were provoked by allergen inhalations in nine children with bronchial asthma. Mechanics of breathing, lung volumes and ventilatory capacity were registered before, during and after provocation. Pulmonary flow resistance, functional residual capacity, and residual volume increased in all children, and vital capacity, forced expiratory volume in 1 sec decreased. Total lung capacity was uninfluenced or decreased. Pulmonary flow resistance increased to a higher value than is usually reached in spontaneous attacks of the same clinical degree of severity. The deviations of the other pulmonary function dimensions were similar to those in spontaneous attacks. The increase of pulmonary flow resistance usually was of short duration. The decrease of FEV1.0 sometimes remained one of several days after attack. The hyperinflation induced was of very short duration.
D001985:Bronchial Provocation Tests; D049673:History, 20th Century