Decreased permeability of glycerol in an ergosterol-less mutant of Candida albicans.
In a comparative study, an ergosterol-less nystatin-resistant mutant of Candida albicans and its ergosterol-producing nystatin-sensitive parental strain were investigated. The sterol mutant showed a more significantly decreased growth yield, respiration and glycerol-uptake activity than the parental strain as the consequence of its altered plasma membrane lipid composition.
D002176:Candida albicans / Q000235:genetics / Q000378:metabolism*; D002463:Cell Membrane Permeability; D004875:Ergosterol / Q000378:metabolism*; D005990:Glycerol / Q000378:metabolism*; D009154:Mutation; D010101:Oxygen Consumption; D013997:Time Factors
D005990:Glycerol; D004875:Ergosterol