title: Jules Dejerine and the third alexia.
abstract: Modern concepts of pure alexia and alexia with agraphia are derived from Dejerine's eloquent clinicopathologic studies of the late 19th century. More recently, a third variety of alexia has been described in association with left frontal lesions causing Broca's aphasia. Dejerine also recognized this "third alexia." For Dejerine, alexia with Broca's aphasia was indispensible to his view of a left-hemisphere language zone in which cortical lesions disrupt all language modalities (speech, reading, and writing). Viewed in light of modern neurolinguistic advances, Dejerine's descriptions of the third alexia are surprisingly prescient.
mesh_terms: D000381:Agraphia / Q000150:complications / Q000266:history*; D001037:Aphasia / Q000150:complications / Q000266:history; D004411:Dyslexia, Acquired / Q000150:complications / Q000266:history*; D049672:History, 19th Century; D006801:Humans