The early history of estriol.
The early history of estriol is reviewed with special emphasis on its isolation, identification, quantitation in tissues and body fluids and its unique biogenesis in the human feto-placental unit. The relationship to epimeric estriols and acidic estrogens and the pharmacokinetic and pharmacodynamic properties which led to a widespread therapeutic use of this compound are also discussed.
D000818:Animals; D002621:Chemistry; D003124:Colorimetry; D004964:Estriol / Q000266:history / Q000302:isolation & purification / Q000502:physiology*; D005260:Female; D049673:History, 20th Century; D006801:Humans; D008431:Maternal-Fetal Exchange; D008954:Models, Biological; D011247:Pregnancy
D004964:Estriol