title: Comparative strength of anterior spinal fixation with bone graft or polymethylmethacrylate. Experimental operations and observations on dogs.
abstract: In 23 dogs, polymethylmethacrylate (PMMA) was safely implanted in the region of the spinal cord. The dogs were treated by bone or cement fixation after anterior excision of a single cervical vertebral body. Fixation was compared at 0-18 weeks, with control values obtained from 11 dogs. Anterior cement fixation did not displace after 18 weeks. The anterior bone graft appeared to achieve adequate fixation strength around six weeks. The strength of the bone-graft fixation increased, while that of cement fixation decreased somewhat with time. At all time intervals, the ratio of energy absorption to structural failure was somewhat higher with bone graft than with PMMA.
mesh_terms: D000818:Animals; D001843:Bone Cements / Q000627:therapeutic use*; D016025:Bone Transplantation; D002574:Cervical Vertebrae / Q000601:surgery; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D007085:Ilium / Q000637:transplantation; D008768:Methylmethacrylates / Q000627:therapeutic use*; D013123:Spinal Fusion / Q000379:methods*; D013314:Stress, Mechanical; D013997:Time Factors
chemical_list: D001843:Bone Cements; D008768:Methylmethacrylates