title: Nitrofurantoin-resistant mutants of Escherichia coli: isolation and mapping.
abstract: Mutants of Escherichia coli resistant to nitrofurantoin have been isolated. The mutations, designated nfnA and nfnB were introduced individually into a multiply auxotrophic E. coli F- strain and mapped by conjugation and transduction. nfnA is located at 79.8 min and nfnB at 13.0 min on the E. coli chromosome.
mesh_terms: D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D009154:Mutation; D009582:Nitrofurantoin / Q000494:pharmacology*
chemical_list: D009582:Nitrofurantoin