Co-existence of enkephalin and adrenalin in the frog adrenal gland.
By means of immunohistochemistry combined with formaldehyde-induced fluorescence microscopy, met-enkephalin-like immunoreactivity was found to occur in the adrenalin -cells of frog adrenal glands. Immunoelectron microscopy demonstrated that the immunoreactive material is confined to the secretory granules. These findings suggest the concomitant release of enkephalin and adrenalin by exocytosis.
D000311:Adrenal Glands / Q000032:analysis*; D000818:Animals; D004744:Enkephalin, Methionine / Q000032:analysis*; D004837:Epinephrine / Q000032:analysis*; D005260:Female; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D011892:Rana catesbeiana / Q000378:metabolism*
D004744:Enkephalin, Methionine; D004837:Epinephrine