Long term consequences of bacterial colonization of the biliary tract after choledochostomy.
We studied 48 patients--36 who underwent cholecystectomy and choledochotomy-choledochostomy for cholesterol gallstones and 12 patients as controls who underwent different types of extrabiliary operations. In our material, we observed that, in a high proportion of instances, infected bile during the early postoperative period remained contaminated for six months postoperatively--in an obviously unobstructed bile duct. In patients in whom Escherichia coli was isolated both early and late postoperatively, a statistical significancy was found. This phenomenon consists of a favorable condition for precipitation of calcium bilirubinate, triggering new pigment stone formation.
D001419:Bacteria / Q000302:isolation & purification*; D001646:Bile / Q000382:microbiology; D001659:Biliary Tract / Q000382:microbiology*; D001663:Bilirubin / Q000032:analysis; D002769:Cholelithiasis / Q000601:surgery; D003135:Common Bile Duct / Q000601:surgery*; D004386:Duodenum; D004926:Escherichia coli / Q000302:isolation & purification; D005766:Gastrointestinal Contents / Q000382:microbiology; D006801:Humans; D013997:Time Factors
D001663:Bilirubin