[Differential aspects of the dynamics of the renin-angiotensin-aldosterone system in obesity with and without hypertension and in essential arterial hypertension].
This report describes the impulsive function of the RAAS investigated in obese and non-obese hypertensives as compared to obese and non-obese normotensives. The aim of the investigation was to clarify whether or not the hypertensive vascular disease accompanying the ponderal excess can be regarded as a well-defined pathophysiologic entity. Data obtained showed that the behavior of the RAAS in hypertensive obese patients is quite different from that of non-obese hypertensives and obese normotensives. Such a difference implies that hypertension of obese people is a biochemically distinguishable entity. This observation corroborates the concept that the clinical association of obesity-hypertension might be regarded as a syndrome with a proper nosographic dignity.
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure; D001835:Body Weight; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology*; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System
D000450:Aldosterone; D012083:Renin
Aspetti differenziali della dinamica del sistema renina-angiotensina-aldosterone nell'obesità con e senza ipertensione e nella ipertensione arteriosa essenziale.