title: Human muscle cell surface antigen 16.3A5 is encoded by a gene on chromosome 11.
abstract: A monoclonal antibody (McAb), 16.3A5, has been characterized that reacts with a cell surface antigen of human muscle cells and a variety of nonmuscle cells. The gene controlling synthesis of 16.3A5 antigen has been assigned to human chromosome 11 by assessing McAb reactivity on a panel of mouse-human cell hybrids. The 16.3A5 has a novel specificity distinct from other chromosome 11-encoded antigens such as W6/34, F10.44.2, TRA1.10, and 4D12 antigens.
mesh_terms: D000328:Adult; D000818:Animals; D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000235:genetics*; D002460:Cell Line; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D002999:Clone Cells; D005260:Female; D005333:Fetus; D005455:Fluorescent Antibody Technique; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000276:immunology; D051379:Mice; D009132:Muscles / Q000378:metabolism*; D011247:Pregnancy
chemical_list: D000911:Antibodies, Monoclonal; D000954:Antigens, Surface