Plasma cell granuloma of the stomach combined with gastric cancer.
An autopsy case of plasma cell granuloma of the stomach combined with gastric cancer is reported. Plasma cell granuloma presumably occurred independently of adenocarcinoma in the stomach, and nodular or diffuse infiltration of plasma cell containing many Russell bodies was observed in the gastric wall, intermingled with lymphocytes. Infiltrating plasma cells were polyclonal in nature as seen by peculiar meshwork patterns of positive immunofluorescence against human gamma, kappa, and lambda chains. Ultrastructurally, globular Russell bodies, 1-7 micrometers in diameter, were located in the rough endoplasmic reticulum and could be divided into two types, smooth-or rough-surfaced one.
D000230:Adenocarcinoma / Q000150:complications; D000368:Aged; D005455:Fluorescent Antibody Technique; D006099:Granuloma / Q000473:pathology*; D006104:Granuloma, Plasma Cell / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*