Mural thrombi in coronary artery disease. Recent advances in pathogenesis, diagnosis, and approaches to treatment.
Detection of ventricular mural thrombi has been facilitated by the introduction of echocardiography, nuclear angiography, and radioactive labeling of platelets. Most of the data regarding the incidence of mural thrombi, pathogenesis of thrombus formation, and predisposing factors for systemic emboli after myocardial infarction that were reported on postmortem studies in the past can now be reexamined in the living patient with these noninvasive methods. The data accumulated from such investigations are now available and the results are reviewed herein. A critique of the usefulness of echocardiography and nuclear methods is also presented.
D000792:Angiography / Q000379:methods; D000925:Anticoagulants / Q000627:therapeutic use; D001792:Blood Platelets; D003327:Coronary Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D003331:Coronary Vessels / Q000473:pathology; D004452:Echocardiography; D004617:Embolism / Q000209:etiology; D006801:Humans; D007204:Indium; D009203:Myocardial Infarction / Q000150:complications; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013927:Thrombosis / Q000175:diagnosis / Q000188:drug therapy
D000925:Anticoagulants; D011868:Radioisotopes; D007204:Indium