Influence of K99 on the phagocytosis and killing of K99-positive Escherichia coli by mouse peritoneal cells in vitro.
The expression of K99-plasmid encoded products was examined to assess their influence on phagocytosis and killing by mouse peritoneal cells. Strains of K99-positive Escherichia coli were cultured under varying conditions which either allowed or inhibited the expression of K99-plasmid products. The survival of phagocytosis by the bacteria was found to depend more on the expression of the K99 antigen than the expression of its associated adhesin.
D000818:Animals; D000942:Antigens, Bacterial / Q000235:genetics; D000954:Antigens, Surface / Q000235:genetics; D001202:Ascitic Fluid / Q000276:immunology; D001427:Bacterial Toxins; D003602:Cytotoxicity, Immunologic; D004926:Escherichia coli / Q000235:genetics / Q000276:immunology*; D066298:In Vitro Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D010587:Phagocytosis; D010957:Plasmids
D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001427:Bacterial Toxins; C031429:K99 antigen