title: The use of sequential analysis to assess patient preference for local skin anaesthesia during knee aspiration.
abstract: Twenty-seven patients requiring bilateral knee aspiration showed no overall preference for or against the use of subcutaneous lignocaine during knee aspiration. The trial result attained a predefined level of significance (beta = 0.1; theta = 0.72) with fewest possible patients (27), using sequential analysis.
mesh_terms: D000368:Aged; D000772:Anesthesia, Local; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007717:Knee; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D013223:Statistics as Topic; D013396:Suction
chemical_list: D008012:Lidocaine