title: [Benzodiazepines in the treatment of epilepsy].
abstract: Diazepam and clonazepam when given by intra- veinous or rectal route are the first-choice treatment of epileptic status. They are active in 80 per cent of cases whatever is the form of the status with a better efficacy in generalized seizures. Clonazepam, chlorazepate, nitrazepam and clobazam are also prescribed as chronic treatment of various forms of epilepsy. However tolerance and side-effects on higher nervous functions are frequent. In the state of the art benzodiazepine utilisation is limited as add-on therapy in severe epilepsies. They may have broader indications in monotherapy.
mesh_terms: D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D001569:Benzodiazepines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001570:Benzodiazepinones / Q000627:therapeutic use; D002675:Child, Preschool; D000078306:Clobazam; D002998:Clonazepam / Q000627:therapeutic use; D003009:Clorazepate Dipotassium / Q000627:therapeutic use; D003975:Diazepam / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy*; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy; D006801:Humans; D007275:Injections, Intravenous; D009567:Nitrazepam / Q000627:therapeutic use; D013226:Status Epilepticus / Q000188:drug therapy; D013488:Suppositories
chemical_list: D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D001570:Benzodiazepinones; D013488:Suppositories; D001569:Benzodiazepines; D000078306:Clobazam; D002998:Clonazepam; D003009:Clorazepate Dipotassium; D009567:Nitrazepam; D003975:Diazepam
vernacular_title: Les benzodiazépines dans le traitement des épilepsies.