Glycosylation of proteins: its implications in diabetic control and complications.
The author shows that nonenzymic glucosylation of proteins can modify the structure and function of proteins isolated from non-insulin-dependent tissues and that these glucosylated proteins, whose normal functions have been altered or removed, may be related to diabetes and some of its sequelae.
D001842:Bone and Bones / Q000378:metabolism; D050260:Carbohydrate Metabolism; D003094:Collagen / Q000378:metabolism; D003920:Diabetes Mellitus / Q000378:metabolism*; D003925:Diabetic Angiopathies / Q000378:metabolism; D003928:Diabetic Nephropathies / Q000378:metabolism; D003929:Diabetic Neuropathies / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008903:Minerals / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*
D003094:Collagen; D005947:Glucose; D006442:Glycated Hemoglobin; D007328:Insulin; D008077:Lipoproteins, LDL; D008565:Membrane Proteins; D008903:Minerals; D011506:Proteins