Monoclonal antibodies to glial fibrillary acidic protein in the cytologic diagnosis of brain tumors.
Monoclonal antibodies were used to immunocytochemically demonstrate the presence or absence of glial fibrillary acidic protein (GFAP) in smear preparations from human intracranial tumors. The results show that this approach may be of great help in the histogenetic classification of such tumors.
D000230:Adenocarcinoma / Q000175:diagnosis; D000911:Antibodies, Monoclonal; D001254:Astrocytoma / Q000175:diagnosis; D001932:Brain Neoplasms / Q000175:diagnosis*; D003581:Cytodiagnosis / Q000379:methods; D005904:Glial Fibrillary Acidic Protein; D005910:Glioma / Q000175:diagnosis; D006801:Humans; D007124:Immunoenzyme Techniques; D007381:Intermediate Filament Proteins / Q000276:immunology*; D008579:Meningioma / Q000175:diagnosis; D009837:Oligodendroglioma / Q000175:diagnosis
D000911:Antibodies, Monoclonal; D005904:Glial Fibrillary Acidic Protein; D007381:Intermediate Filament Proteins