Lymphocytic infiltration of the skin (Jessner): a T-cell lymphoproliferative disease.
Recent studies have suggested that Jessner 's lymphocytic infiltration of the skin and lymphocytoma cutis both represent pseudo-B-cell lymphomas. We have now done immunohistochemical studies on frozen skin sections of six patients with lymphocytic infiltration of the skin. In all cases a predominance of T lymphocytes was observed and B lymphocytes were sparse or completely absent. These results indicate that Jessner 's lymphocytic infiltration of the skin is a T-cell lymphoproliferative disease which, unlike lymphocytoma cutis, cannot be regarded as a pseudo-B-cell lymphoma.
D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology; D005260:Female; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008232:Lymphoproliferative Disorders / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000276:immunology / Q000473:pathology*; D012871:Skin Diseases / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology*
D000911:Antibodies, Monoclonal; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II