title: Multiforms of megamodulin-dependent protein kinases from baker's yeast.
abstract: Multiforms of megamodulin-dependent protein kinases (M-PK) were partially purified from baker's yeast by excluding endogenous megamodulin with histone, and then by gel filtration with Sephadex G-200. The stimulation of M-PK in the presence of Mg2+, Mn2+ or Co2+ was enhanced by yeast megamodulin. In addition, similar augmented activity of M-PK was also noted in the presence of Mg2+ by megamodulins prepared from E. coli, bovine brain and wheat germ.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D002352:Carrier Proteins / Q000378:metabolism*; D002413:Cations, Divalent; D002417:Cattle; D004926:Escherichia coli / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins; D011494:Protein Kinases / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology*
chemical_list: D002352:Carrier Proteins; D002413:Cations, Divalent; D047908:Intracellular Signaling Peptides and Proteins; C015482:protein kinase modulator; D011494:Protein Kinases