Mazindol in the control of micturition.
The appetite suppressant mazindol has been compared with a placebo in the control of incontinence in a double-blind cross-over trial. Twenty-five patients were entered; 4 were withdrawn for protocol violations. The underlying diagnoses were determined; 19 had stable detrusors and 6 unstable. Seventeen patients made a complete response to mazindol for a 68% overall response rate.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D008454:Mazindol / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D014549:Urinary Incontinence / Q000188:drug therapy*
D007211:Indoles; D008454:Mazindol