Candida albicans meningitis in a parenteral drug abuser.
We have described a patient with meningitis due to Candida albicans, in whom the only identifiable risk factor was a history of intravenous amphetamine abuse. Despite intravenous therapy with 2 gm of amphotericin B and concurrent 5-fluorocytosine, symptoms, CSF pleocytosis, and hypoglycorrhachia persisted. After a brief course of intrathecal amphotericin B therapy, the patient improved clinically and the CSF returned to normal.
D000328:Adult; D000662:Amphetamines; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008581:Meningitis / Q000175:diagnosis* / Q000209:etiology; D019966:Substance-Related Disorders / Q000150:complications*
D000662:Amphetamines