The effect of infused prostaglandin F2 alpha on plasma antidiuretic hormone and renin activity in early human pregnancy.
The effect of infused prostaglandin F2 alpha plasma antidiuretic hormone and renin activity in early pregnancy was investigated in eight women. After infusion for one and three hours (infusion speed 50 micrograms/min) the PRA had decreased significantly. During the same time the blood pressure also showed a decreasing tendency. No changes were found in plasma vasopressin concentration.
D001794:Blood Pressure / Q000187:drug effects; D015237:Dinoprost; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011460:Prostaglandins F / Q000008:administration & dosage / Q000494:pharmacology*; D012083:Renin / Q000097:blood*; D014667:Vasopressins / Q000097:blood*
D011460:Prostaglandins F; D014667:Vasopressins; D015237:Dinoprost; D012083:Renin