Ceftazidime in the treatment of pediatric patients with severe urinary tract infections due to Pseudomonas spp.
Fifteen pediatric patients with complicated urinary tract infections due to Pseudomonas spp. were treated for 10 to 18.5 days with ceftazidime administered intramuscularly twice daily. Urine sterilization during therapy was obtained in all patients. Three patients had relapses which were cured with a second course of ceftazidime. Minor liver damage, eosinophilia, and Candida superinfection developed in one patient each.
D000293:Adolescent; D002097:C-Reactive Protein / Q000032:analysis; D002442:Ceftazidime; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects; D011552:Pseudomonas Infections / Q000188:drug therapy*; D013997:Time Factors; D014552:Urinary Tract Infections / Q000188:drug therapy*
D002511:Cephalosporins; D002097:C-Reactive Protein; D002442:Ceftazidime