High-pressure liquid chromatographic assay of Bay n 7133 in human serum.
A high-pressure liquid chromatographic method that includes a Sep-Pak (Waters Associates, Inc., Milford , Mass.) preparation of human serum was employed for the quantitative assay of Bay n 7133. Drug levels of 0.1 to 20 micrograms/ml could be detected. No interference from amphotericin B was found in the chromatographic analysis of Bay n 7133.
D000666:Amphotericin B / Q000097:blood; D000935:Antifungal Agents / Q000494:pharmacology; D001431:Bacteriological Techniques; D002175:Candida / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D014230:Triazoles / Q000097:blood* / Q000494:pharmacology
D000935:Antifungal Agents; D014230:Triazoles; D000666:Amphotericin B; C037494:vibunazole