The treatment of neonatal isoimmune thrombocytopenia with intravenous immunoglobin (IgG i.v.).
We present a report of the use of IgG i.v. to treat clinically manifest neonatal immune thrombocytopenia. The IgG i.v. was administered at a daily dosage of 0.4 g/kg body weight for 5 days. Treatment was started when the child was 3 days old and had a platelet count of 2 X 10(9)/l. Four days later the platelet count had risen to 200 X 10(9)/l. The diagnosis of immune thrombocytopenia was confirmed by platelet typing of the mother's and child's platelets and identification of anti-platelet antibodies in maternal serum.
D001787:Blood Group Incompatibility / Q000628:therapy; D001792:Blood Platelets / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D006932:Hyperbilirubinemia / Q000628:therapy; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000627:therapeutic use*; D007231:Infant, Newborn; D007263:Infusions, Parenteral; D010789:Phototherapy; D013921:Thrombocytopenia / Q000276:immunology / Q000628:therapy*
D007074:Immunoglobulin G