Necrotic cellulitis. A localized form of septic vasculitis.
Cutaneous biopsy specimens from two patients with localized, bacterial, necrotic cellulitis showed a neutrophilic vasculitis with fibrin thrombi, changes indistinguishable from those seen in a third patient with bacterial septicemia. Additional clinical information may be needed before a definitive diagnosis of localized or systemic septic vasculitis can be made with certainty. The clinical and microscopic features of the lesions and their pathologic mechanisms are discussed.
D000328:Adult; D000368:Aged; D001431:Bacteriological Techniques; D002481:Cellulitis / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D009336:Necrosis; D018805:Sepsis / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D014657:Vasculitis / Q000150:complications / Q000382:microbiology / Q000473:pathology*