title: The early history of estriol.
abstract: The early history of estriol is reviewed with special emphasis on its isolation, identification, quantitation in tissues and body fluids and its unique biogenesis in the human feto-placental unit. The relationship to epimeric estriols and acidic estrogens and the pharmacokinetic and pharmacodynamic properties which led to a widespread therapeutic use of this compound are also discussed.
mesh_terms: D000818:Animals; D002621:Chemistry; D003124:Colorimetry; D004964:Estriol / Q000266:history / Q000302:isolation & purification / Q000502:physiology*; D005260:Female; D049673:History, 20th Century; D006801:Humans; D008431:Maternal-Fetal Exchange; D008954:Models, Biological; D011247:Pregnancy
chemical_list: D004964:Estriol