title: [Biological effectiveness of ionizing radiations of various quality in Escherichia coli bacteria (a theoretical analysis). The induction of single- and double-stranded DNA breaks].
abstract: Peculiarities of induction of single- and double-strand DNA breaks (SSR and DSB) in E. coli cells by ionizing radiation of different LET are discussed. On the basis of the model proposed the dependence of the yield of SSR and different types of DSB upon LET was calculated. It was shown that enzymatic DSB were mainly induced by gamma-radiation. As LET increased the yield of enzymatic DSB decreased and that of direct DSR increased.
mesh_terms: D004247:DNA / Q000528:radiation effects*; D004269:DNA, Bacterial / Q000528:radiation effects*; D004277:DNA, Single-Stranded / Q000528:radiation effects*; D004735:Energy Transfer / Q000528:radiation effects; D004926:Escherichia coli / Q000528:radiation effects*; D005720:Gamma Rays; D008433:Mathematics; D008954:Models, Biological; D012062:Relative Biological Effectiveness
chemical_list: D004269:DNA, Bacterial; D004277:DNA, Single-Stranded; D004247:DNA
vernacular_title: Biologicheskaia éffektivnost' ioniziruiushchikh izlucheniĭ raznogo kachestva u bakteriĭ Eescherichia coli (teoreticheskiĭ analiz). Induktsiia odnonitevykh i dvukhnitevykh razryvov DNK.