Pemphigus vegetans. Neumann type and Hallopeau type.
Two cases of pemphigus vegetans are presented, one of the Neumann type and one of the Hallopeau type. The differences between the two subsets are clinical presentation and course. Patients with the Hallopeau type often have a relatively benign disease, require lower doses of systemic corticosteroids, and usually have a prolonged remission. Patients with the Neumann type have a course similar to pemphigus vulgaris, need higher doses of systemic corticosteroids, and have relapses and remissions. The histologic findings in the vegetating lesions are similar in both types. The immunopathologic features of both types are indistinguishable and similar to pemphigus vulgaris. IgM staining of eosinophilic microabscesses was observed in one case.
D000038:Abscess / Q000276:immunology / Q000473:pathology; D000051:Acantholysis / Q000276:immunology / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006119:Groin; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D009061:Mouth Mucosa / Q000276:immunology / Q000473:pathology; D010392:Pemphigus / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D012867:Skin / Q000276:immunology / Q000473:pathology
D007075:Immunoglobulin M; D011241:Prednisone