Carcinoid tumor occurring in a teratoid malformation of the kidney. An immunohistochemical study.
A case of a carcinoid tumor of the kidney that was intimately related to a mixed dysplastic and teratomatous lesion is reported. This lesion displayed focal transitional, mucinous, and endocrine differentiations. Immunofluorescence studies permit the identification of three immunoreactive products: somatostatin, glucagon, and serotonin. It is suggested that the carcinoid tumor arises from this peculiar lesion, which exhibits cells of endocrine lineage.
D000368:Aged; D002276:Carcinoid Tumor / Q000032:analysis / Q000473:pathology*; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D007680:Kidney Neoplasms / Q000032:analysis / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D009392:Nephrectomy; D009384:Paraneoplastic Endocrine Syndromes / Q000032:analysis / Q000473:pathology*; D013724:Teratoma / Q000032:analysis / Q000473:pathology*