Prolongation of the survival of skin grafts in mice by PUVA treatment.
The combined application of psoralen and UVA radiation to skin grafts induced a prolongation of the survival time of the grafts in mice. This was observed using the H-Y barrier, an allogeneic barrier without H-2 disparities, and a strong H-2 incompatible barrier. The effect is probably due to a reduction of antigen-presenting cells, or to other, unknown mechanisms.
D000818:Animals; D005260:Female; D006085:Graft Survival / Q000528:radiation effects*; D006183:H-2 Antigens; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011701:PUVA Therapy; D010778:Photochemotherapy; D016038:Skin Transplantation
D006183:H-2 Antigens