The long-term results of the use of human amnion in the treatment of leg ulcers.
In a retrospective study of 28 patients whose venous leg ulcers had been treated with human amnion prior to split-skin grafting, the rate of recurrence of ulceration was 50% at 1 year. Repeated grafting of ulcers which recurred rapidly after the first skin graft was worthwhile as many then remained healed.
D000650:Amnion / Q000637:transplantation*; D006801:Humans; D007871:Leg Ulcer / Q000601:surgery*; D011183:Postoperative Complications; D012008:Recurrence; D016038:Skin Transplantation; D014945:Wound Healing