[Cells of the vascular wall synthesize thromboxane].
Cultured endothelial and smooth muscle cells, as well as vascular tissue samples derived from human coronary arteries and minipig aorta produce thromboxane A2 in trace amounts. The identity of this substance was characterized using a specific thromboxane synthetase inhibitor. Thromboxane (TXB2) was measured by means of specific radioimmunoassay. The biological importance of this phenomenon is unclear.
D000818:Animals; D001011:Aorta / Q000378:metabolism*; D002478:Cells, Cultured; D004727:Endothelium / Q000166:cytology / Q000378:metabolism; D011464:Epoprostenol / Q000096:biosynthesis; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D013552:Swine; D013929:Thromboxane B2 / Q000096:biosynthesis*; D013931:Thromboxanes / Q000096:biosynthesis*
D013931:Thromboxanes; D013929:Thromboxane B2; D011464:Epoprostenol
Gefässwandzellen synthetisieren Thromboxan.