title: Clinical comparison of thiothixene and thioridazine in schizophrenic adolescents.
abstract: Of 21 schizophrenic adolescents given thiothixene or thioridazine, many responded poorly or experienced sedation. Because sedation necessitates dose reductions, which limit therapeutic response, for schizophrenic adolescents high-potency neuroleptics may be preferable to the more sedating low-potency drugs.
mesh_terms: D000293:Adolescent; D002648:Child; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D012894:Sleep Stages; D013881:Thioridazine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013888:Thiothixene / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D013888:Thiothixene; D013881:Thioridazine