[Primary choriocarcinoma of the stomach. Immunohistochemistry study of a case and review of the literature].
A rare tumor, primary choriocarcinoma of the stomach occurred in a 68 year-old man. Histologic examination of the tumor revealed two components, choriocarcinoma and adenocarcinoma. The liver metastasis displayed only choriocarcinoma, the lymph nodes metastasis only adenocarcinoma. The diagnosis was confirmed by demonstration of beta HcG in serum and urines by radioimmunoassay and within syncytiotrophoblast cells by immunoperoxidase staining. A review of the literature is done. The pathogenesis is discussed with hypothesis that this tumor represents a form of retro-differentiation of a preexisting carcinoma. However, this diagnosis will only be certain when a metastasis of a non gestational, non gonadal choriocarcinoma will be eliminated.
D000368:Aged; D002822:Choriocarcinoma / Q000209:etiology / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007124:Immunoenzyme Techniques; D007158:Immunologic Techniques; D008297:Male; D011863:Radioimmunoassay; D013274:Stomach Neoplasms / Q000209:etiology / Q000473:pathology*
Choriocarcinome primitif de l'estomac. Etude immunohistochimique d'un cas et revue de la littérature.