[Fundamental and clinical studies on ceftazidime in the field of obstetrics and gynecology].
Fundamental and clinical studies were performed on ceftazidime ( CAZ ), a new cephem antibiotic. Following a single intravenous administration of 1 g dose of CAZ , the transfer of CAZ to the internal genital organs was good. The transfer of CAZ to retroperitoneal fluid was excellent. In a clinical trial, CAZ was given to 6 patients with obstetrical and gynecological infections. The efficacy was evaluated as excellent in 3 cases and good in the other 3 cases. No adverse effects were observed in any of the patients treated with CAZ .
D000328:Adult; D000368:Aged; D002442:Ceftazidime; D002511:Cephalosporins / Q000378:metabolism* / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010249:Parametritis / Q000188:drug therapy; D010388:Pelvis; D010538:Peritonitis / Q000188:drug therapy
D002511:Cephalosporins; D002442:Ceftazidime