title: Effect of variations in dialysate temperature on blood pressure during hemodialysis.
abstract: The effect on BP of alteration in dialysate temperature was studied in 150 hemodialysis treatments in 17 patients using a randomized, double-blind protocol. Each patient was treated using dialysate at 35.6 degrees C, 36.7 degrees C, and 37.8 degrees C. Mean BP during 35.6 degrees C dialysis was significantly higher than during 36.7 degrees C or 37.8 degrees C treatments. Symptomatic hypotensive episodes were more frequent at a dialysate temperature of 37.8 degrees C than during use of cooler dialysates. Modest changes in dialysate temperature thus appear to affect BP during hemodialysis. Dialysate cooler than that routinely employed has a beneficial effect while warmer dialysate has a detrimental one on intradialytic BP. The use of dialysate at least 1 degree C cooler than "isothermic" levels may be appropriate.
mesh_terms: D001794:Blood Pressure; D001831:Body Temperature; D001835:Body Weight; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007022:Hypotension / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011674:Pulse; D006435:Renal Dialysis; D012965:Sodium Chloride / Q000008:administration & dosage; D013696:Temperature
chemical_list: D012965:Sodium Chloride