A randomized controlled trial of cervical cerclage in women at high risk of spontaneous preterm delivery.
The effect of cervical suture on pregnancy outcome was studied in 194 women with a high risk (approximately 30%) of having a late abortion or a preterm delivery. The women were randomly allocated either to have a cervical suture inserted (n = 96) or to be managed without a suture (n = 98). There was no evidence that cervical cerclage either prolonged gestation or improved survival. Patients allocated to receive cerclage spent significantly longer in hospital, even when the period of admission for insertion was excluded. The patients in the cerclage group were more likely to receive tocolytic drugs, and more of them experienced puerperal pyrexia, although these differences between the groups were not statistically significant.
D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000601:surgery*; D002986:Clinical Trials as Topic; D005260:Female; D005865:Gestational Age; D006801:Humans; D008487:Medical History Taking; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy; D011897:Random Allocation; D012306:Risk; D013537:Sutures; D002581:Uterine Cervical Incompetence / Q000601:surgery