title: Relapsing polychondritis. A case report and literature review.
abstract: Relapsing polychondritis is a systemic disorder characterized by recurrent inflammation and degeneration of cartilaginous tissue. The eyes, ears, nose, larynx, trachea, and articular areas are commonly involved. While ocular involvement, hearing, and vestibular dysfunction are frequently present, aortic valve and root disease as well as vasculitis also may occur. While the cause remains unknown, an autoimmune pathogenesis appears likely. Thus, dapsone and/or systemic corticosteroids remain the predominant effective therapies. Another case of relapsing polychondritis with an associated vasculitis syndrome is presented as well as a review of the current literature.
mesh_terms: D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D003937:Diagnosis, Differential; D006099:Granuloma / Q000150:complications; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012871:Skin Diseases / Q000150:complications; D014657:Vasculitis / Q000150:complications*