title: Haemopoietic tissue in Perinereis cultrifera Grübe: cytological identification and observations after treatment with lead.
abstract: A perivascular tissue made up of two different types of cells (one with a slightly basophilic cytoplasm and many Fe+++ ions, the other with haemopigments) has been demonstrated in Perinereis cultrifera Grübe by means of histochemical and cytochemical techniques. These two types of cells probably cooperate in the production of the respiratory pigment. Treatment with lead nitrate (0.02 ppm) for up to a maximum of five days caused a progressive cytological alteration with inhibition of haemoglobin synthesis.
mesh_terms: D000818:Animals; D000845:Annelida / Q000033:anatomy & histology*; D001808:Blood Vessels / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects; D005455:Fluorescent Antibody Technique; D006454:Hemoglobins / Q000096:biosynthesis*; D006651:Histocytochemistry; D007501:Iron / Q000378:metabolism; D007854:Lead / Q000494:pharmacology*; D009566:Nitrates / Q000494:pharmacology*; D010858:Pigmentation
chemical_list: D006454:Hemoglobins; D009566:Nitrates; D007854:Lead; C017461:lead nitrate; D007501:Iron