Steroid treatment and aseptic necrosis of the femoral head in renal transplant recipients.
The subject of our study was 546 renal transplant recipients with a graft survival for minimum 12 months. Of these, 29 renal recipients (5.3%) developed aseptic necrosis of the femoral head. The examination revealed that there were no significant differences between the renal recipients with hip necrosis and the control group in the total quantities of administered glucocorticosteroids, whereas there was a highly significant correlation between the two groups in the number of the intravenously administered methylprednisolone pulse doses.
D001379:Azathioprine / Q000627:therapeutic use; D005271:Femur Head Necrosis / Q000209:etiology*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D016030:Kidney Transplantation; D011183:Postoperative Complications / Q000209:etiology
D005938:Glucocorticoids; D001379:Azathioprine