Assessment of the remanent antibacterial effect of a 2% triclosan-detergent preparation on the skin.
A method of quantifying the remanent antibacterial effect of a 2% triclosan preparation in detergent following three consecutive applications on the forearm of 20 volunteers over 2 h, is described with reference to its efficacy against a gentamicin- and multiply-resistant serotype of Klebsiella aerogenes. The relevance of the residual activity of triclosan and other skin antiseptics in surgical and hygienic hand disinfection are discussed.
D003902:Detergents / Q000494:pharmacology*; D006235:Hand Disinfection; D006801:Humans; D007711:Klebsiella pneumoniae / Q000254:growth & development; D010647:Phenyl Ethers / Q000494:pharmacology*; D012044:Regression Analysis; D013501:Surface-Active Agents / Q000494:pharmacology*; D013997:Time Factors; D014260:Triclosan / Q000494:pharmacology*
D003902:Detergents; D010647:Phenyl Ethers; D013501:Surface-Active Agents; D014260:Triclosan