The use of flexible film isolators for housing experimental animals.
The change-over from conventional husbandry to the housing of minimal-disease experimental animals kept in flexible-film isolators resulted in improved survival and thus more definitive experimental results. The disadvantages and advantages of the change are discussed.
D000818:Animals; D000830:Animals, Laboratory; D001424:Bacterial Infections / Q000401:mortality; D016026:Bone Marrow Transplantation; D003524:Cyclosporins / Q000494:pharmacology; D004780:Environment, Controlled; D006799:Housing, Animal; D007165:Immunosuppression Therapy; D051381:Rats; D011919:Rats, Inbred Strains; D014916:Whole-Body Irradiation
D003524:Cyclosporins