Retinal oxygen tension in diabetic dogs following insulin infusion.
We measured preretinal oxygen tensions using a microelectrode in dogs made diabetic with alloxan. The intravenous administration of insulin did not affect preretinal oxygen tension over the two hours it could be continuously accurately measured. Furthermore, the oxygen-hemoglobin equilibrium curves measured before and two hours after insulin administration did not change.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D004285:Dogs; D005260:Female; D007263:Infusions, Parenteral; D007328:Insulin / Q000008:administration & dosage / Q000494:pharmacology*; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000187:drug effects*; D012160:Retina / Q000378:metabolism*
D001786:Blood Glucose; D007328:Insulin; D010100:Oxygen