title: Pathogenesis and treatment of hypertension in renal tuberculosis.
abstract: 39 patients underwent partial or total unilateral nephrectomy for treatment of renal tuberculosis. Before surgery, blood pressure was increased in 12 cases (30%). 5 patients had only mild hypertension which was not modified following surgery. 7 patients had moderate to severe hypertension, and in 5 of them blood pressure was normalized following nephrectomy, indicating a renal pressure mechanism. Special investigations in some of these patients revealed no evidence of a pathogenic role of the adrenergic system, but support the participation of the renin-angiotensin system in at least some patients with hypertension associated with renal tuberculosis.
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure; D001810:Blood Volume; D004837:Epinephrine / Q000097:blood; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000097:blood / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D009638:Norepinephrine / Q000097:blood; D011379:Prognosis; D012083:Renin / Q000097:blood; D014398:Tuberculosis, Renal / Q000097:blood / Q000601:surgery*; D014882:Water-Electrolyte Balance
chemical_list: D000450:Aldosterone; D012083:Renin; D009638:Norepinephrine; D004837:Epinephrine