Identification and prognostic implications of tumor infiltrating lymphocytes--a review.
Cancer patients who have many tumor infiltrating lymphocytes (TIL) tend to have better prognoses. A relationship between prognosis and TIL or regional lymph node response is present in several malignant diseases. TIL are mainly T lymphocytes, as ascertained by immunological methods. Results of studies on T-lymphocyte subsets comprising TIL using monoclonal antibodies (OKT series and Leu series) are summarized in this review.
D001943:Breast Neoplasms / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007167:Immunotherapy; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*; D011379:Prognosis