[Malaria caused by multi-resistant Plasmodium falciparum contracted in Tanzania].
In a severe case of malaria, the chemosensitivity of a Plasmodium falciparum strain from a traveller to Tanzania who underwent chemoprophylaxis treatment with chloroquine (600 mg weekly) was evaluated in vitro. In the 28 hours maturation assay and a 72 hours proliferation assay, the strain proved to be highly resistant to chloroquine and to have a reduced sensibility to the sulfadoxin - pyrimethamin association.
D000328:Adult; D002738:Chloroquine / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000188:drug therapy / Q000469:parasitology*; D008297:Male; D010963:Plasmodium falciparum / Q000187:drug effects*; D011739:Pyrimethamine / Q000627:therapeutic use; D013413:Sulfadoxine / Q000627:therapeutic use; D013636:Tanzania
D013413:Sulfadoxine; D002738:Chloroquine; D011739:Pyrimethamine
Paludisme à Plasmodium falciparum multi-résistant contracté en Tanzanie.