Sequential interaction of glia maturation factor with insulin.
Astroblasts in culture proliferated when exposed to glia maturation factor for at least 2 hours and then to insulin, but not when exposed in the reverse order. The sequential relation suggests that glia maturation factor is a competence factor.
D000818:Animals; D001253:Astrocytes / Q000187:drug effects / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004347:Drug Interactions; D020904:Glia Maturation Factor; D006133:Growth Substances / Q000494:pharmacology* / Q000502:physiology; D007328:Insulin / Q000494:pharmacology* / Q000502:physiology; D051379:Mice; D008807:Mice, Inbred BALB C; D009419:Nerve Tissue Proteins / Q000494:pharmacology* / Q000502:physiology; D051381:Rats
D020904:Glia Maturation Factor; D006133:Growth Substances; D007328:Insulin; D009419:Nerve Tissue Proteins