Comparison of iohexol with meglumine-Na diatrizoate for intravenous digital subtraction angiography.
Iohexol, a new non-ionic water-soluble contrast medium, was tested for digital intravenous angiography of the cervical and intracranial vessels. In a double blind study involving 40 adult patients, iohexol and meglumine-Na diatrizoate were compared for safety, patient tolerance, and radiographic image quality. Iohexol was shown to be safe and generally produced less patient discomfort, leading to a lower incidence of motion, swallowing or cough artifacts.
D000328:Adult; D000368:Aged; D000792:Angiography / Q000379:methods*; D002533:Cerebral Angiography / Q000379:methods; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000633:toxicity; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine / Q000633:toxicity; D004311:Double-Blind Method; D004361:Drug Tolerance; D006801:Humans; D007463:Iodobenzoates; D007472:Iohexol; D008875:Middle Aged; D009333:Neck / Q000098:blood supply; D013382:Subtraction Technique; D014283:Triiodobenzoic Acids / Q000633:toxicity
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D007472:Iohexol