Effects of arginine aspartate and its components on growth hormone, insulin and glucagon secretion in the rat.
The effects of orally administered arginine aspartate (250 mg per kg) on the secretion of insulin, glucagon and growth hormone in the rat have been compared with those of equimolar doses of arginine (142 mg per kg) and aspartic acid (108 mg per kg). There were no significant changes in the blood levels of insulin and glucagon. Arginine aspartate increased growth hormone levels whereas its two components failed to induce any significant changes. This stimulatory effect on growth hormone is discussed.
D000818:Animals; D001120:Arginine / Q000494:pharmacology*; D001224:Aspartic Acid / Q000494:pharmacology*; D001786:Blood Glucose / Q000378:metabolism; D005934:Glucagon / Q000097:blood / Q000378:metabolism*; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D007328:Insulin; D001224:Aspartic Acid; D013006:Growth Hormone; D005934:Glucagon; D001120:Arginine; C024891:arginine aspartate