Evaluation of isotretinoin treatment of hidradenitis suppurativa.
Eight patients with a long-standing hidradenitis suppurativa were treated with isotretinoin, 0.71 to 1.2 mg/kg/day, as a single agent for 4 months and have had follow-up of at least 2 months. The clinical status was judged as cleared in one patient, almost cleared in three patients, improved in one patient, not changed in two patients, and worse in one patient.
D000293:Adolescent; D000328:Adult; D001050:Apocrine Glands / Q000187:drug effects*; D002986:Clinical Trials as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D015474:Isotretinoin; D008297:Male; D008875:Middle Aged; D013543:Sweat Gland Diseases / Q000188:drug therapy*; D013545:Sweat Glands / Q000187:drug effects*; D013997:Time Factors; D014212:Tretinoin / Q000008:administration & dosage* / Q000633:toxicity; D014847:Vulvitis / Q000188:drug therapy*
D014212:Tretinoin; D015474:Isotretinoin