title: [Complications of preoperative high-dose-rate iridium-192 irradiation in cervix uteri carcinoma].
abstract: A report is given about the experience in preoperative, nonfractionated high-dose iridium-192 irradiation in cases of carcinoma of the cervix uteri. A few days prior to radical hysterectomy a dose of 20 Gy (in 2 cm distance) was applied locally by means of a loop-applicator (afterloading technique, Buchler). In cases without postoperative irradiation severe vaginal necroses, in cases with postoperative irradiation severe local and peripheral lesions were observed. In 8 of 10 cases irradiated pre- and postoperatively, another surgical intervention was necessary because of complications in the urinary or intestinal tract. This publication is presented as a warning for preoperative high-dose irradiation with 20 Gy applied locally in cases of carcinoma of the cervix uteri.
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007495:Iridium / Q000009:adverse effects*; D011184:Postoperative Period; D011832:Radiation Injuries / Q000453:epidemiology; D011868:Radioisotopes / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery
chemical_list: D011868:Radioisotopes; D007495:Iridium
vernacular_title: Komplikationen der präoperativen High-dose-rate-Iridium-192-Vorbestrahlung beim Gebärmutterhalskarzinom.