A double-blind trial of chronic cerebellar stimulation in twelve patients with severe epilepsy.
Twelve patients with severe intractable epilepsy were treated by chronic cerebellar stimulation under double-blind conditions for six months. No reduction in seizure frequency occurred that could be attributed to stimulation, though eleven of the patients considered that the trial had helped them. One patient experienced fewer episodes of incontinence during stimulation. Cerebellar stimulation in its present form cannot be recommended for the treatment of severe intractable epilepsy.
D000328:Adult; D002531:Cerebellum / Q000503:physiopathology; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004599:Electric Stimulation Therapy / Q000295:instrumentation / Q000379:methods*; D004827:Epilepsy / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male