title: Plasma renin activity (PRA) and plasma aldosterone in the adrenal cortex hyperactivity. Studies on 50 hypertensive patients.
abstract: The authors have studied on 50 patients hospitalized in the Adrenal Pathology unit of the Institute of Endocrinology, the etiopathogeny of arterial hypertension (AH) in hypercorticism and the therapeutic implications, arriving at the conclusion that in 20% of the cases AH was probably due to an increased activity of renin-angiotensin and in 47% to elevated levels of aldosterone. The authors hypothesize that AH in the remaining 30% of the hypercorticism cases in this study is due to other mineralocorticoids in excess and suggest that the treatment should be pathogenic and strictly individualized.
mesh_terms: D000308:Adrenocortical Hyperfunction / Q000150:complications*; D000328:Adult; D000450:Aldosterone / Q000097:blood*; D004573:Electrolytes / Q000097:blood; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D008901:Mineralocorticoids / Q000097:blood; D012083:Renin / Q000097:blood*
chemical_list: D004573:Electrolytes; D008901:Mineralocorticoids; D000450:Aldosterone; D012083:Renin