title: [Is pindolol suitable for the therapy of glaucoma? Evaluation of the dose-effect of various concentrations of pindolol eyedrops].
abstract: Various concentrations of Pindolol eye drops (0.17%, 0.35%, 0.5%, 0.72%, 1.0%), a beta-blocking agent with an intrinsic sympathomimetic activity, were investigated with regard to their pressure-lowering effect in open-angle glaucoma. It was found that all of these concentrations reduce intraocular pressure, but that only the 1% solution has a significantly stronger effect after 24 hours. It is therefore preferable to use this relatively high concentration, especially as it is not accompanied by a bronchopulmonary risk.
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D010869:Pindolol / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009883:Ophthalmic Solutions; D010869:Pindolol
vernacular_title: Eignet sich Pindolol zur Therapie des Glaukoms? Dosiswirkungsprüfung verschieden konzentrierter Pindolol-Augentropfen.