title: Association of alpha-crystallin with actin in cultured lens cells.
abstract: The nature of the beaded filaments in the lens fiber cell has been debated for some time. One explanation is that beaded filaments represent an association of alpha-crystallin with actin filaments. By using a double labelling technique that allowed us to view actin filaments and alpha-crystallin in the same cell we have demonstrated that some of the alpha-crystallin in lens cells is indeed associated with actin.
mesh_terms: D000199:Actins / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D003459:Crystallins / Q000378:metabolism*; D003599:Cytoskeleton / Q000648:ultrastructure*; D005455:Fluorescent Antibody Technique; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007903:Lens Capsule, Crystalline / Q000166:cytology; D007908:Lens, Crystalline / Q000166:cytology*; D051379:Mice
chemical_list: D000199:Actins; D003459:Crystallins