Resection followed by vascularized bone autograft in patients with possible recurrence of malignant bone tumors after conservative treatment.
In conservative treatment of malignant bone tumors, assessment of the local condition is difficult. The radiological changes seen in the irradiated tumor and the frequent occurrence of pathological fractures at this site may give rise to the fear that the tumor has relapsed. Resection of the whole of the involved bone is the best way to assure adequate local control but the extent of the bone defect and the bad local conditions secondary to irradiation make reconstruction hazardous. In two patients (one with Ewing's sarcoma of the femur and one with osteogenic sarcoma of the humerus) the authors used a free, vascularized fibular graft for the reconstruction having obtained consolidation of the limb after resection of the irradiated tumor, with preservation of its function. The encouraging results obtained have suggested a conservative attitude as primary treatment of specific malignant bone tumors.
D000293:Adolescent; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D016025:Bone Transplantation; D001842:Bone and Bones / Q000098:blood supply; D005266:Femoral Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D006811:Humerus / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local; D010025:Osteoradionecrosis / Q000209:etiology; D012516:Osteosarcoma / Q000532:radiotherapy / Q000601:surgery*; D012512:Sarcoma, Ewing / Q000532:radiotherapy / Q000601:surgery*