Renal transplantation in Australia and New Zealand, 1963-1982: report from the ANZ Data Registry.
In Australia, more than 400 transplants are performed annually, the majority of primary grafts from CADs. The patient survival rate that has increased gradually over the period from 1976 to 1982 may be attributed to decreased steroid use for both rejection and maintenance immunosuppression. Our data suggest that B and DR locus antigens are important histocompatibility antigens, that the effects of additive for both loci, and the influence of histocompatibility at the B locus and DR locus is stronger for the transfused sensitized (responder) patient. Age has more influence on patient survival than on graft survival.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001315:Australia; D001803:Blood Transfusion; D002102:Cadaver; D006085:Graft Survival; D006680:HLA Antigens / Q000032:analysis; D015235:HLA-B Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006650:Histocompatibility Testing; D006801:Humans; D007430:Intraoperative Care; D016030:Kidney Transplantation; D008875:Middle Aged; D009520:New Zealand; D012042:Registries
D006680:HLA Antigens; D015235:HLA-B Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II