Serratia marcescens pyarthrosis and osteomyelitis.
We have reported a case of Serratia marcescens arthritis and osteomyelitis in a young man whose source of infection appeared to be a single episode of intravenous amphetamine use. Multiple antibiotics and aggressive surgical management were necessary to effect a cure. He eventually responded to a three-week course of amikacin and moxalactam given in conjunction with surgical debridement of all involved areas.
D000328:Adult; D000583:Amikacin / Q000008:administration & dosage; D000661:Amphetamine; D001170:Arthritis, Infectious / Q000209:etiology*; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination; D004756:Enterobacteriaceae Infections / Q000628:therapy; D006801:Humans; D008297:Male; D009070:Moxalactam / Q000008:administration & dosage; D010019:Osteomyelitis / Q000209:etiology*; D012706:Serratia marcescens / Q000302:isolation & purification; D019966:Substance-Related Disorders / Q000150:complications; D013492:Suppuration / Q000209:etiology / Q000628:therapy
D000583:Amikacin; D000661:Amphetamine; D009070:Moxalactam