title: The culture of dermal papilla cells from human hair follicles.
abstract: Dermal papillae were isolated from human hair follicles and primary cell cultures were established from the papilla explants. The cultured papilla cells spread slowly, initially as a monolayer, and eventually formed multi-layered parallel arrays of fibroblast-like cells. At the edges of expanding colonies the cells were large and flattened and showed a tendency to form clumps. The behaviour of human dermal papilla cells in culture is very similar to that reported in cultures of papilla cells from rat vibrissa follicles.
mesh_terms: D002455:Cell Division; D002478:Cells, Cultured; D003584:Cytological Techniques; D006197:Hair / Q000166:cytology*; D006801:Humans; D008854:Microscopy, Electron; D008858:Microscopy, Phase-Contrast; D012867:Skin / Q000166:cytology*