title: Hepatitis B virus antigens made in microbial cells immunise against viral infection.
abstract: Chimpanzees have been vaccinated successfully against hepatitis B virus with preparations of the viral antigens made in microbial cells by genetic engineering methods.
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006511:Hepatitis B Antigens / Q000235:genetics / Q000276:immunology*; D007114:Immunization; D008297:Male; D002679:Pan troglodytes; D012441:Saccharomyces cerevisiae / Q000235:genetics; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D006511:Hepatitis B Antigens; D014765:Viral Vaccines