Anaphylaxis due to chloramphenicol.
A patient with group B Streptococcal meningitis and a history of penicillin allergy sustained an anaphylactic reaction following intravenous chloramphenicol. The purity of the infusate was confirmed by reverse-phase high-speed liquid chromatography. Anaphylaxis is a rare event following chloramphenicol administration, but physicians should be aware of this complication, especially in patients with prior exposure to the drug.
D000707:Anaphylaxis / Q000139:chemically induced*; D002701:Chloramphenicol / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008581:Meningitis / Q000209:etiology; D008875:Middle Aged; D013290:Streptococcal Infections; D013292:Streptococcus agalactiae
D002701:Chloramphenicol