Antimonocyte serum. The effect on blast transformation, RFC and PFC formation.
The paper is a continuation of the previous experiments. The results show that the rabbit and sheep antisera specific for monocytes after absorption with leukocytes deprived of phagocytosing cells do not affect E-rosetting cells and do not impair the blast transformation of normal leukocytes stimulated by PHA in vitro. However, they reduce the number of EAC rosettes formed by leukocytes and they decrease the ability of leukocytes to produce antibodies for SRBC.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D002469:Cell Separation; D003602:Cytotoxicity, Immunologic; D006462:Hemolytic Plaque Technique; D007106:Immune Sera / Q000276:immunology / Q000494:pharmacology*; D007962:Leukocytes / Q000276:immunology; D008213:Lymphocyte Activation; D011817:Rabbits; D011946:Receptors, Antigen; D011951:Receptors, Complement; D012397:Rosette Formation; D013552:Swine
D007106:Immune Sera; D011946:Receptors, Antigen; D011951:Receptors, Complement; C029764:antimacrophage globulin