Reactivity of presumed anti-natural killer cell antibody Leu 7 with intrafollicular T lymphocytes.
This report describes the presence of a T lymphocyte subpopulation in germinal centres of lymph follicles. This subpopulation is defined by reactivity with Leu 7 antibody, in addition to OKT11, OKT1, OKT3 and OKT4 positivity. The functional activity of this T lymphocyte subpopulation is a matter of discussion and has to be clarified by functional studies of purified populations of these cells.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007694:Killer Cells, Natural / Q000276:immunology*; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000473:pathology; D008224:Lymphoma, Follicular / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*
D000911:Antibodies, Monoclonal