title: Biologic considerations in the selection and use of restorative materials.
abstract: In this article the defense mechanisms of the pulp and pulp reactions to injury were briefly reviewed. Iatrogenic pulp injury was emphasized and guidelines for prevention of such injury were provided. These could be summarized as follows: Never cut dry. Always use a water coolant to prevent heat generation and desiccation of dentin. Use a protective base or liner with materials that are known to be irritating to the pulp (groups II and III) regardless of cavity depth. Use a protective base in all deep cavities where the possibility of a microscopic exposure of the pulp exists, regardless of the nature of the material to be used for restoration.
mesh_terms: D003764:Dental Materials / Q000494:pharmacology*; D003782:Dental Pulp / Q000187:drug effects* / Q000293:injuries / Q000502:physiology; D003785:Dental Pulp Capping; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000187:drug effects / Q000293:injuries; D003809:Dentin, Secondary / Q000502:physiology; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D011671:Pulpitis / Q000473:pathology / Q000503:physiopathology
chemical_list: D003764:Dental Materials