Relationship of endocrine status on the stimulatory effect of ethanol on hepatic very low density lipoprotein synthesis.
The normal stimulatory effect of an acute oral dose of ethanol on hepatic very low density lipoprotein synthetic rate is abolished in thyroidectomized rats but not in adrenalectomized rats. This lack of stimulation by ethanol can be explained in part by the decreased rate of hepatic fatty acid esterification to neutral lipids in thyroidectomized animals.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D008079:Lipoproteins, VLDL / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical; D013963:Thyroid Hormones / Q000502:physiology*; D013965:Thyroidectomy
D008079:Lipoproteins, VLDL; D013963:Thyroid Hormones; D000431:Ethanol