[Phospholipid content of the rat lung and surfactant during the administration of hydrocortisone or insulin and in hypoxic hypoxia].
After acute hypoxia (3 hrs, P-200 mm Hg) content of total phospholipids and of their fractions was not altered in rat lung parenchyma, but the phospholipid composition, changed due to preadministration of hydrocortisone or insulin, was normalized. After the hypoxia concentration of phospholipids in surfactant was decreased mainly due to a loss of phosphatidyl choline; the phenomenon was noted and after preadministration of the hormones.
D000818:Animals; D006854:Hydrocortisone / Q000494:pharmacology*; D000860:Hypoxia / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology*; D008168:Lung / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010715:Phosphatidylglycerols / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D011663:Pulmonary Surfactants / Q000378:metabolism*; D051381:Rats; D013109:Sphingomyelins / Q000378:metabolism
D007328:Insulin; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010715:Phosphatidylglycerols; D010743:Phospholipids; D011663:Pulmonary Surfactants; D013109:Sphingomyelins; D006854:Hydrocortisone
Soderzhanie fosfolipidov v legkikh i surfaktante krys pri vvedenii gidrokortizona ili insulina i deĭstvii gipoksicheskoĭ gipoksii.