[Limitations of indications of clotrimazole-hydrocortisone and its components. A double-blind study].
Efficacy and tolerability of ointment/water emulsion, containing the combination of clotrimazole and hydrocortisone (Canesten HC) were compared with the two components. 4 groups of indications were chosen and 192 (16 X 3 X 4) patients treated. In all groups and symptoms of this comparison the best efficacy was with the combination product. Side effects which have to be attributed to this topical treatment could not be detected.
D002986:Clinical Trials as Topic; D003022:Clotrimazole / Q000009:adverse effects / Q000627:therapeutic use*; D003872:Dermatitis / Q000188:drug therapy* / Q000382:microbiology; D004311:Double-Blind Method; D004338:Drug Combinations / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects / Q000627:therapeutic use*; D007093:Imidazoles / Q000627:therapeutic use*; D009824:Ointments; D011897:Random Allocation; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D013997:Time Factors
D004338:Drug Combinations; D007093:Imidazoles; D009824:Ointments; C038774:clotrimazole, hydrocortisone drug combination; D003022:Clotrimazole; D006854:Hydrocortisone
Indikationsabgrenzung zwischen Clotrimazol/Hydrocortison und seinen beiden Komponenten. Eine doppelblinde Studie.