title: Effect of lectins from leguminous seeds on rat duodenal enterokinase activity.
abstract: Enterokinase activity from rat duodenal brush borders was assayed in vitro in the presence of purified lectins from 3 leguminous seeds. Noncompetitive inhibition of the enzyme was observed in each case. Phaseolus hemagglutinin was the most potent inhibitor among the 3 lectins tested.
mesh_terms: D000818:Animals; D003208:Concanavalin A / Q000494:pharmacology; D004386:Duodenum / Q000201:enzymology*; D004765:Enteropeptidase / Q000037:antagonists & inhibitors*; D007887:Fabaceae; D037102:Lectins / Q000494:pharmacology*; D008871:Microvilli / Q000201:enzymology; D010835:Phytohemagglutinins / Q000494:pharmacology; D037121:Plant Lectins; D010946:Plants, Medicinal; D011480:Protease Inhibitors; D051381:Rats; D012639:Seeds; D030262:Soybean Proteins
chemical_list: D037102:Lectins; D010835:Phytohemagglutinins; D037121:Plant Lectins; D011480:Protease Inhibitors; D030262:Soybean Proteins; C028824:soybean lectin; D003208:Concanavalin A; D004765:Enteropeptidase