Postinfectious glomerulonephritis in a renal allograft associated with a mycotic aneurysm of a coronary artery.
Postinfectious glomerulonephritis is well known to occur after various infections but is rare in renal allografts, perhaps as a result of immunosuppressive therapy. This report describes a 47-year-old man who, seven years after receiving a cadaveric renal transplant, had biopsy-proved crescentic glomerulonephritis presenting with gross hematuria and rapidly progressive renal failure. The patient underwent cardiac surgery to define an abnormal structure shown on echocardiography, and a mycotic aneurysm of the left circumflex artery was discovered. Such aneurysms are uncommon and rarely diagnosed during life. This case appears to be the first report of glomerulonephritis associated with a mycotic aneurysm of a coronary artery and one of the few reports of postinfectious glomerulonephritis in a renal allograft.
D000785:Aneurysm, Infected / Q000150:complications*; D003327:Coronary Disease / Q000150:complications*; D005921:Glomerulonephritis / Q000209:etiology*; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged