[Formation of experimental obesity by Crisco].
Randomized male litter S.D. rats (weight: about 60 g, 1 group: 10 rats) were used. By using Crisco (hydrogenated cotton seed oil) within the limits of 10 approximately 60%, the intake of the 30% group was high and a good incidence rate of obesity (about 100%) was obtained in the 6 month experiment. In the 30% group, increases of wet weight in perirenal retroperitoneal and subcutaneous fat depots, increases of the number and diameter of fat cells (perirenal retroperitoneal fat depot), elevations of liver fat % and serum insulin level, and a fall of liver phosphoenolpyruvate carboxykinase activity were observed in the 3 month experiment.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003369:Cottonseed Oil / Q000378:metabolism*; D004041:Dietary Fats / Q000378:metabolism*; D004195:Disease Models, Animal; D007328:Insulin / Q000097:blood; D050356:Lipid Metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008297:Male; D009765:Obesity / Q000201:enzymology / Q000209:etiology*; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D003369:Cottonseed Oil; D004041:Dietary Fats; D007328:Insulin; D010729:Phosphoenolpyruvate Carboxykinase (GTP)