title: Dose fractionation effects in low dose rate irradiation of jejunal crypt stem cells.
abstract: Jejunal crypt survival after fractionated total body irradiation of C3H mice given at dose rates of 1.2 or 0.08 Gy/min was studied. The fractionation effect was more pronounced at the high dose rate than at the low dose rate. Analysis of the data according to the linear-quadratic survival curve model yielded an alpha/beta value at 1.2 Gy/min of 13.3 Gy and at 0.08 Gy/min of 96 Gy.
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D007583:Jejunum / Q000528:radiation effects*; D051379:Mice; D008809:Mice, Inbred C3H; D013234:Stem Cells / Q000528:radiation effects*; D014916:Whole-Body Irradiation
chemical_list: D003037:Cobalt Radioisotopes