Klebsiella-induced LIF response in Klebsiella infection and ankylosing spondylitis.
Lymphocyte transformation and leucocyte migration inhibition was studied in Klebsiella-sensitized patients, ankylosing spondylitis patients and healthy controls. The results show that mononuclear cells from ankylosing spondylitis patients respond more vigorously to Klebsiella, one of the 'trigger' bacteria, than do mononuclear cells from healthy persons, either with or without HLA-B27.
D000328:Adult; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications / Q000276:immunology*; D007961:Leukocyte Migration-Inhibitory Factors / Q000096:biosynthesis*; D008213:Lymphocyte Activation; D008222:Lymphokines / Q000096:biosynthesis*; D013167:Spondylitis, Ankylosing / Q000209:etiology / Q000276:immunology*
D007961:Leukocyte Migration-Inhibitory Factors; D008222:Lymphokines