[Cytotoxicity in psoriasis].
The authors study three cytotoxicity system in psoriasis: direct cytotoxicity (DCC), antibodies mediated cytotoxicity (ADCC) and activated lymphocytes mediated cytotoxicity (PCC). The results of DCC and PCC are in the normal values, while ADCC are a somewhat increased, showing a hyperactivity of this system, which could explain some physiopathological phenomena of this disease. We consider this finding as secondary to an alteration of the immune system by dysbalance of B-T lymphocytes.
D000293:Adolescent; D000328:Adult; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D011565:Psoriasis / Q000276:immunology*
Citotoxicidad en psoriasis.