Enteric-type adenocarcinoma of the nasal cavity. An electron microscopic and immunocytochemical study.
A primary adenocarcinoma of the nasal cavity with light microscopic, electron microscopic, and immunocytochemical features of an enteric-type carcinoma is presented. The carcinoma contained a variety of dense-core granules similar to those seen in enterochromaffin cells of different functional types. Some granules demonstrated an immunoreactivity with serotonin, cholecystokinin, gastrin, somatostatin and leu-enkephalin antibodies. It is suggested that the endocrine cells in the neoplasm belong to the non-neuroectodermal paraneurone system.
D000230:Adenocarcinoma / Q000032:analysis / Q000473:pathology / Q000648:ultrastructure*; D000368:Aged; D002766:Cholecystokinin / Q000032:analysis; D002838:Chromaffin System / Q000648:ultrastructure*; D004759:Enterochromaffin Cells / Q000032:analysis / Q000648:ultrastructure*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000032:analysis / Q000473:pathology / Q000648:ultrastructure*; D012701:Serotonin / Q000032:analysis; D014660:Vasoactive Intestinal Peptide / Q000032:analysis
D012701:Serotonin; D014660:Vasoactive Intestinal Peptide; D002766:Cholecystokinin