title: [Iopromide, a new contrast medium for angiography. Clinical study and comparison with other low-osmolar contrast media].
abstract: In a multi-centre randomized double-blind study the ionic dimer ioxaglate was compared with the nonionic monomer iopromide. In a second randomized double-blind study iopamidol was included in the trial. It was shown that with low-osmolar substances sensitivity to pain and warmth occurred to only a slight extent, whether the contrast medium was ionic or non-ionic. An advantage of the non-ionic preparation was the definitely lower incidence of skin-rash, dizziness, nausea and vomiting.
mesh_terms: D000792:Angiography / Q000379:methods*; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000009:adverse effects*; D004311:Double-Blind Method; D006801:Humans; D007463:Iodobenzoates; D007472:Iohexol / Q000031:analogs & derivatives*; D007479:Iopamidol; D007483:Iothalamic Acid / Q000009:adverse effects / Q000031:analogs & derivatives; D007485:Ioxaglic Acid; D011674:Pulse / Q000187:drug effects; D011897:Random Allocation; D013997:Time Factors; D014283:Triiodobenzoic Acids / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007483:Iothalamic Acid; D007472:Iohexol; C038192:iopromide; D007479:Iopamidol; D007485:Ioxaglic Acid
vernacular_title: Iopromid, ein neues Kontrastmittel zur Angiographie. Klinische Studie und Vergleich mit anderen niederosmolaren Kontrastmitteln.