Histological findings in sutured and fibrin-glued microvascular anastomosis.
A new method of microvascular anastomosis is presented. A sufficient sutureless telescoping anastomosis was achieved using fibrin adhesive (Tissucol, Immuno GmbH, Heidelberg, FRG) and a Fogarty embolectomy catheter (American Hospital Supply, Deutschland GmbH, Munich, FRG) as an internal splint in the abdominal aorta of Sprague-Dawley rats. The main advantage of this technique is its short application time. Histological examinations mostly showed accelerated healing compared with sutured anastomosis.
D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D008866:Microsurgery / Q000379:methods*; D051381:Rats; D011919:Rats, Inbred Strains; D013536:Suture Techniques; D013917:Thrombin / Q000627:therapeutic use*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014656:Vascular Surgical Procedures / Q000379:methods*; D014680:Veins / Q000637:transplantation; D014945:Wound Healing / Q000187:drug effects
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin