New aspects of the pathogenesis of immune complex glomerulonephritis: formation of subepithelial deposits.
Data obtained from experimental studies show the importance of electrical charge in the development of glomerular subepithelial deposits, especially when the latter arise via in situ immune complex formation. Theoretical consideration makes it likely that cationic antigens contribute to subepithelial deposit formation in cases of human glomerulonephritis.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology*; D000941:Antigens; D002412:Cations; D004553:Electric Conductivity; D004594:Electrophysiology; D005921:Glomerulonephritis / Q000276:immunology* / Q000503:physiopathology; D006801:Humans
D000936:Antigen-Antibody Complex; D000941:Antigens; D002412:Cations