Approaches to sample size estimation in the design of clinical trials--a review.
Over the last decade, considerable interest has focused on sample size estimation in the design of clinical trials. The resulting literature is scattered over many textbooks and journals. This paper presents these methods in a single review and comments on their application in practice.
D002986:Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D010352:Patient Dropouts; D011897:Random Allocation; D012306:Risk; D013223:Statistics as Topic; D013997:Time Factors