title: [Chemotherapy of advanced non-small cell bronchogenic carcinoma with cisplatin and vindesine].
abstract: 29 patients with advanced non-small cell lung cancer were treated with cisplatin and vindesine according to the protocol of Gralla et al. 1 complete and 7 partial remissions were achieved. Because of the short observation time we cannot say anything about duration of remission and survival time of the patients. Toxicity observed during 67 cycles was severe. Because of side effects treatment had to be stopped in 10 patients. According to remission rates this protocol is comparable to other cisplatin combinations.
mesh_terms: D000328:Adult; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D002283:Carcinoma, Bronchogenic / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D014747:Vinblastine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D014751:Vindesine
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D002945:Cisplatin; D014751:Vindesine
vernacular_title: Chemotherapie des fortgeschrittenen nicht-kleinzelligen Bronchialkarzinoms mit Cisplatin und Vindesin.