Resuscitation of trauma patients with type-specific uncrossmatched blood.
The present study was undertaken to determine the safety of type-specific uncrossmatched blood transfusions for severely hypovolemic trauma patients. During a 3-year period 875 units of type-specific uncrossmatched blood were given to 160 severely hypovolemic trauma patients who could not be adequately resuscitated with crystalloid solutions. No transfusion reactions resulted from the administration of type-specific uncrossmatched blood. Subsequent major crossmatch failed to identify either blood incompatibility or significant antibodies. Type-specific uncrossmatched blood is safe and is a rapidly available alternative to crossmatched blood in the severely hypovolemic trauma patient.
D000017:ABO Blood-Group System / Q000276:immunology; D001787:Blood Group Incompatibility; D001788:Blood Grouping and Crossmatching; D001803:Blood Transfusion / Q000266:history; D049668:History, 15th Century; D049670:History, 17th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D012151:Resuscitation; D012769:Shock / Q000209:etiology / Q000628:therapy*; D014947:Wounds and Injuries / Q000150:complications*
D000017:ABO Blood-Group System