title: Aspergillosis of the paranasal sinuses x-ray diagnosis, histopathology, and clinical aspects.
abstract: Aspergillosis is not a rare disease of the paranasal sinuses; more than 80 cases were reported from 1976 to 1982 in the University ENT Clinic at Graz, Austria. Of 59 patients studied, 27 presented almost metal-dense x-ray shadows resembling foreign bodies in one of the sinuses. By means of light and electron microscopic investigations as well as x-ray fluorescence analysis, it can be demonstrated that these areas are equivalent to local enrichment of calcium phosphate in the center of the noninvasive fungal masses in the sinuses. A detailed description of the histopathology of Aspergillus fumigatus is given. For clinical diagnosis, the detection of almost metal-dense x-ray shadows in the absence of foreign-body history in our experience may be regarded as almost certain for aspergillosis of the paranasal sinuses.
mesh_terms: D015502:Absorptiometry, Photon; D001228:Aspergillosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D001232:Aspergillus fumigatus / Q000254:growth & development; D002130:Calcium Phosphates / Q000032:analysis; D002133:Calcium Sulfate / Q000032:analysis; D006801:Humans; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014131:Trace Elements / Q000032:analysis
chemical_list: D002130:Calcium Phosphates; D014131:Trace Elements; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous; D002133:Calcium Sulfate