MM 14201, a new epoxyquinone derivative with antibacterial activity produced by a species of Streptomyces.
A new antibiotic designated MM 14201 has been detected in a culture of Streptomyces sp. NCIB 11813. Methods for the production and purification of MM 14201 are described. Biological evaluation has shown it has broad spectrum antibacterial activity being most effective against Serratia and Pseudomonas sp. Structural studies are reported which have demonstrated MM 14201 is a new epoxyquinone derivative.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D005285:Fermentation; D005658:Fungi / Q000187:drug effects; D006193:Haemophilus influenzae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011809:Quinones / Q000302:isolation & purification / Q000633:toxicity; D013297:Streptococcus pyogenes / Q000187:drug effects; D013302:Streptomyces / Q000254:growth & development*
D000900:Anti-Bacterial Agents; D011809:Quinones; C040318:MM 14201