title: [Squaric acid dibutyl ester in the treatment of severe alopecia areata].
abstract: The results of the treatment with topical applications of squaric acid dibutylester in seven cases of severe alopecia areata are reported. In adult patients this form of therapy is very effective to achieve a total hair regrowth, but its use should be strictly limited to the most serious cases, recalcitrant to other therapeutical methods.
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D055598:Chemical Phenomena; D002621:Chemistry; D002648:Child; D002675:Child, Preschool; D003503:Cyclobutanes / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000139:chemically induced; D008297:Male; D010859:Pigmentation Disorders / Q000139:chemically induced
chemical_list: D000276:Adjuvants, Immunologic; D003503:Cyclobutanes; C020637:squaric acid dibutyl ester
vernacular_title: Dibutiléster del ácido escuárico en el tratamiento de la alopecia areata grave.