Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate.
Comparing iohexol 240 mg I/ml, iohexol 300 mg I/ml and meglumine-Ca metrizoate 200 mg I/ml in phlebography of the leg in patients on or without anticoagulants, no sign of post-phlebographic thrombosis was found using the 125I-fibrinogen uptake test and repeat phlebography. More adverse reactions occurred with metrizoate than with iohexol. Metrizoate provided significantly poorer demonstration than the two iohexol concentrations with higher iodine content.
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000633:toxicity; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007463:Iodobenzoates; D007472:Iohexol; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D008794:Metrizoic Acid / Q000031:analogs & derivatives / Q000633:toxicity; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010690:Phlebography / Q000009:adverse effects; D013927:Thrombosis / Q000209:etiology / Q000517:prevention & control; D014283:Triiodobenzoic Acids / Q000633:toxicity
D000925:Anticoagulants; D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008794:Metrizoic Acid; C021342:methylglucamine metrizoate