title: Biologic and clinical importance of proinsulin.
mesh_terms: D000293:Adolescent; D000818:Animals; D001483:Base Sequence; D002096:C-Peptide / Q000502:physiology; D004274:DNA, Recombinant; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism; D004340:Drug Contamination; D005260:Female; D005796:Genes; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000032:analysis / Q000097:blood / Q000235:genetics / Q000502:physiology; D007330:Insulin Antibodies / Q000032:analysis; D007340:Insulinoma / Q000097:blood; D008099:Liver / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000097:blood; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000378:metabolism; D011384:Proinsulin / Q000032:analysis / Q000096:biosynthesis / Q000502:physiology*; D014176:Protein Biosynthesis; D011498:Protein Precursors / Q000096:biosynthesis; D012333:RNA, Messenger / Q000032:analysis
chemical_list: D002096:C-Peptide; D004274:DNA, Recombinant; D007328:Insulin; D007330:Insulin Antibodies; D011498:Protein Precursors; D012333:RNA, Messenger; C013737:preproinsulin; D011384:Proinsulin; D005947:Glucose