High-dose corticosteroids in the treatment of pulseless idioventricular rhythm.
Pulseless idioventricular rhythm (PIVR) is a slow electrical rhythm of ventricular origin without mechanical activity, and it is associated with a mortality rate that approaches 100%. In 1976 high-dose corticosteroids were advocated as beneficial in the treatment of PIVR. A critical review of the early literature suggests that the favorable outcome may have been attributable to variables other than treatment with high-dose steroids. Recent prospective clinical trials have not confirmed the salutory effect of steroids in this dysrhythmia.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000209:etiology; D006323:Heart Arrest / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D011674:Pulse
D000305:Adrenal Cortex Hormones