title: [Stimulation of wound healing by tetrachlordecaoxide. Results of a randomized double-blind study].
abstract: In 38 patients with chronic therapeutically resistant wounds, which, in 25 cases, had been existing for more than one year, Tetrachlorodecaoxide ( TCDO ) in a water solution containing glycerin was analyzed for its capacity to induce wound healing and compared in this respect to the standard in moist wound treatment, physiological sodium chloride. The results of the clinical trial demonstrate that the TCDO solution is significantly superior to physiological saline in local wound treatment regarding the degree of wound smear reduction, the formation of wound granulation tissue, the stimulation of epithelisation on the wound borders and the shrinking of the wound surface. The differences in therapeutic efficiency are so large that, in spite of the relatively small patient samples (21 + 17) it was possible to verify the superiority of a method for wound treatment in a randomized double blind clinical trial.
mesh_terms: D000368:Aged; D002713:Chlorine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006097:Granulation Tissue / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D011897:Random Allocation; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000188:drug therapy
chemical_list: D010087:Oxides; D002713:Chlorine; C041955:tetrachlorodecaoxide
vernacular_title: Stimulation der Wundheilung durch Tetrachlordecaoxid (TCDO). Ergebnisse einer randomisierten Doppelblindstudie.