title: Fatty acid synthesis in brown adipose tissue of the Mongolian gerbil (Meriones unguiculatus): influence of acclimation temperature on synthesis in brown adipose tissue and the liver in relation to whole-body synthesis.
abstract: Fatty acid synthesis was measured in vivo with 3H2O in Mongolian gerbils acclimated at different temperatures. At 31 degrees C the highest rate of synthesis was in the liver, and the liver accounted for approximately one half of whole-body synthesis. At 20 and 40 degrees C, the highest synthesis rate (per g tissue) occurred in brown adipose tissue, and this tissue was estimated to account for some 15% of whole-body synthesis at both these temperatures. In contrast to other rodent species whole-body fatty acid synthesis in the Mongolian gerbil was lower in cold-acclimated than warm-acclimated animals, despite the cold-induced increase in energy intake.
mesh_terms: D000064:Acclimatization; D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001833:Body Temperature Regulation; D001835:Body Weight; D004435:Eating; D005227:Fatty Acids / Q000096:biosynthesis*; D005849:Gerbillinae / Q000378:metabolism*; D007328:Insulin / Q000097:blood; D008099:Liver / Q000378:metabolism*; D008297:Male; D013696:Temperature
chemical_list: D001786:Blood Glucose; D005227:Fatty Acids; D007328:Insulin