Acyclovir ointment does not affect the dark-field examination in primary syphilis.
In the cases of two patients and in a rabbit with experimental syphilis, treatment of primary syphilis lesions with 5% acyclovir ointment did not affect detection of Treponema pallidum by dark-field microscopy. These results indicate that the dark-field examination need not be delayed in patients whose genital ulcers have been treated with acyclovir ointment.
D000212:Acyclovir / Q000627:therapeutic use*; D000328:Adult; D000818:Animals; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011817:Rabbits; D013587:Syphilis / Q000175:diagnosis* / Q000188:drug therapy; D014210:Treponema pallidum / Q000302:isolation & purification
D009824:Ointments; D000212:Acyclovir