Late onset pyridoxine-responsive sideroblastic anaemia after allogeneic bone marrow transplantation.
We report the late development of transfusion-dependent sideroblastic anaemia in two patients who received a bone marrow transplant for chronic granulocytic leukaemia in blast crisis and T-cell acute lymphoblastic leukaemia respectively. Treatment with pyridoxine has either stopped or reduced these transfusion requirements. Red cell transfusion dependence later after marrow transplantation is rare and sideroblastic anaemia must be excluded.
D000328:Adult; D000756:Anemia, Sideroblastic / Q000188:drug therapy / Q000209:etiology*; D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy; D007951:Leukemia, Myeloid / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy; D011736:Pyridoxine / Q000627:therapeutic use; D013601:T-Lymphocytes; D013997:Time Factors
D011736:Pyridoxine