[Radiation resistance: a concept in need of review or a stubborn problem for radio-oncology?].
Many tumors are considered to be radio-resistant. Reviewing recent literature on clinical results, this notion of radio resistance needs to be revised. With new technics and improved dosimetry it has become possible to control locally even well differentiated carcinomas and achieve clear survival benefits. Three examples illustrate the importance of radiation therapy of prostatic cancer as a well established procedure. It would seem that radiation therapy in colorectal tumors of certain stages is becoming part of initial treatment. A case is made out for meningeoma, where surgery undoubtedly remains the first approach; after incomplete removal or in locally inoperable patients, radiation therapy may be of value.
D000368:Aged; D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000532:radiotherapy; D008579:Meningioma / Q000532:radiotherapy; D008875:Middle Aged; D009369:Neoplasms / Q000532:radiotherapy*; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011836:Radiation Tolerance; D012004:Rectal Neoplasms / Q000532:radiotherapy
Strahlenresistenz: revisionsbedürftiger Begriff oder hartnäckiges Problem der Radio-Onkologie?