title: [Fundamental and clinical studies on ceftazidime in the field of paediatrics].
abstract: Ceftazidime (CAZ), a new cephem antibiotic for injection, was used in the field of paediatrics, and the following results were obtained. Antibacterial activity of CAZ was high against Gram-negative rods including P. aeruginosa, but slightly low against Gram-positive cocci. Absorption and excretion of CAZ were rapid, and 90% or more was excreted at 6 hours after administration. The clinical efficacy was excellent or good in all the 4 cases treated with CAZ, and no side effects were observed.
mesh_terms: D000367:Age Factors; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002442:Ceftazidime; D002511:Cephalosporins / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male
chemical_list: D002511:Cephalosporins; D002442:Ceftazidime