title: Croup: pathogenesis and management.
abstract: Croup syndromes are common in children, most frequently being infectious in origin. Children present with a slow progression of inspiratory and expiratory stridor and a croupy, "barking seal" cough. Children are variably febrile and with progression of disease, exhaustion, agitation, cyanosis and air hunger may develop. The evaluation of the patient must focus on the degree of respiratory distress and associated findings. Epiglottitis and foreign body aspiration must be excluded. Management is primarily dependent upon administration of humidified air. Children with moderate to severe croup benefit from racemic epinephrine and steroids. Admission is indicated in children with stridor at rest, evidence of exhaustion, toxicity or respiratory distress. Active airway intervention is rarely required but may be life saving if obstruction develops.
mesh_terms: D002648:Child; D003440:Croup / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004826:Epiglottitis / Q000175:diagnosis; D004837:Epinephrine / Q000627:therapeutic use; D005547:Foreign Bodies / Q000150:complications; D006801:Humans; D007819:Laryngeal Edema / Q000473:pathology; D007827:Laryngitis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D007830:Larynx / Q000000981:diagnostic imaging; D011654:Pulmonary Edema / Q000209:etiology; D064705:Racepinephrine; D011859:Radiography; D013203:Staphylococcal Infections / Q000150:complications; D014132:Trachea / Q000000981:diagnostic imaging; D014777:Virus Diseases / Q000150:complications
chemical_list: D003907:Dexamethasone; D064705:Racepinephrine; D004837:Epinephrine