title: Closure of contaminated wounds. Biologic and technical considerations.
abstract: The current knowledge in the field of wound bacteriology and host resistance to wound infection is summarized. This knowledge provides specific measures to increase the success rate of primary wound healing in contaminated wounds that must be closed.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000009:adverse effects; D001161:Arteriosclerosis / Q000150:complications; D003646:Debridement; D048909:Diabetes Complications; D005547:Foreign Bodies / Q000150:complications; D006406:Hematoma / Q000150:complications; D006801:Humans; D007113:Immunity, Innate; D007511:Ischemia / Q000150:complications; D008722:Methods; D009369:Neoplasms / Q000150:complications; D009748:Nutrition Disorders / Q000150:complications; D012769:Shock / Q000150:complications; D016038:Skin Transplantation; D013524:Surgical Flaps; D013537:Sutures / Q000009:adverse effects; D014946:Wound Infection / Q000150:complications / Q000276:immunology / Q000382:microbiology / Q000601:surgery*
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents