title: An evaluation of coronary regulation by the 99mTc bolus technique.
abstract: A new non-invasive method for investigating total coronary blood supply is presented. This method is based on the principle of indicator dilution of a radio-nuclide bolus (99Tc), requiring a scintillation camera with high sensitivity and high picture resolution. The first findings obtained from 83 patients are shown. With 4.61 +/- 1.19% of cardiac output the mean values of the rates of coronary perfusion obtained at rest in subjects with a normal heart differed significantly from those obtained for patients with certain coronary occlusions (8.18 +/- 3.99% of cardiac output) and from those obtained for hypertensive patients (Stages I-III). Double examinations carried out on 20 patients yielded an adequate reproducibility. The mean deviation of the double examinations from one another was 16%.
mesh_terms: D000328:Adult; D000368:Aged; D002302:Cardiac Output; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D048909:Diabetes Complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D007201:Indicator Dilution Techniques; D008875:Middle Aged; D011877:Radionuclide Imaging; D013667:Technetium
chemical_list: D013667:Technetium