title: Prophylactic antibiotics for curettage abortion.
abstract: Opinion is divided as to the advisability of routine use of prophylactic antibiotics for curettage abortion. Six studies, including three randomized clinical trials, suggest that prophylaxis reduces infectious morbidity associated with curettage abortions by about one half. Three other studies, two involving prophylaxis for instillation abortions and one involving a vaginal antiseptic for curettage abortion, support the hypothesis that antimicrobial prophylaxis reduces morbidity. Tetracyclines are commonly used for this purpose. The cost of routine prophylaxis even with an expensive tetracycline would appear to be offset by the savings in direct and indirect costs. Prophylaxis may help prevent both short-term morbidity and potential late sequelae, such as ectopic pregnancy and infertility.
mesh_terms: D000028:Abortion, Induced / Q000379:methods*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003365:Costs and Cost Analysis; D004107:Dilatation and Curettage; D005260:Female; D006801:Humans; D011247:Pregnancy; D011292:Premedication / Q000191:economics; D014619:Vacuum Curettage
chemical_list: D000900:Anti-Bacterial Agents