[Evaluation of immune status in gastric cancer using Su-Ps skin test].
Immunotherapy for gastric cancer has been adopted by any institutes recently. However, immunoparameters which exactly express patients' immune status have not been determined. In this study, the Su-Ps skin test was tried to evaluate whether or not this reaction could become a usable immunoparameter. Conclusions were as follows: 1) Late-stage patients showed a significantly weak response in the Su-Ps skin test compared to early-stage patients when examined preoperatively. 2) Su-Ps skin reaction became stronger after gastrectomy in early-stage patients, while the contrary result was observed in late-stage patients. 3) Postoperative Su-Ps skin tests showed a stronger response than preoperative tests regardless of the patients' stage, when patients received OK-432 treatment. The Su-Ps skin test reaction seemed to be well-correlated with the patients' immune status as above, so that this test can be chosen for evaluation of immunotherapy.
D006801:Humans; D008213:Lymphocyte Activation; D010835:Phytohemagglutinins / Q000494:pharmacology; D010844:Picibanil / Q000627:therapeutic use; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D012867:Skin / Q000276:immunology*; D012882:Skin Tests; D013274:Stomach Neoplasms / Q000276:immunology* / Q000628:therapy; D013297:Streptococcus pyogenes; D014374:Tuberculin Test
D010835:Phytohemagglutinins; D011135:Polysaccharides, Bacterial; D010844:Picibanil