[Effect of indomethacin on the recovery of hematopoiesis in mice after total gamma irradiation].
In experiments on mice it was demonstrated that after the administration of indomethacin the CFUc, survived after the irradiation, enter the exponential phase of growth 3 days earlier than the controls do. The time of doubling of cells in number is invariable. The accelerated repopulation of haemopoietic cells improves the haemopoiesis status at the height of acute radiation sickness.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D005720:Gamma Rays; D006410:Hematopoiesis / Q000187:drug effects* / Q000528:radiation effects; D007213:Indomethacin / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011448:Prostaglandin Antagonists / Q000494:pharmacology; D013997:Time Factors; D014916:Whole-Body Irradiation
D011448:Prostaglandin Antagonists; D007213:Indomethacin
Vliianie indometatsina na vosstanovlenie gemopoéza u mysheĭ posle obshchego gamma-oblucheniia.