Chromosomal assignment of the murine gene encoding the transformation-related protein p53.
p53 is a transformation-related protein that is encoded by the cellular genome and is synthesized at elevated levels in a wide range of different cell line types and in primary tumors of various species. By using several independently established anti-p53 monoclonal antibodies, it was possible to distinguish between p53 of mouse origin and p53 of Chinese hamster origin. By analysis of a series of mouse X Chinese hamster hybrid cell lines containing various mouse chromosomes, we mapped the p53 gene product to mouse chromosome 11.
D000818:Animals; D000911:Antibodies, Monoclonal; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D006822:Hybrid Cells; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010750:Phosphoproteins / Q000235:genetics*; D013045:Species Specificity; D014170:Transformation, Genetic; D016159:Tumor Suppressor Protein p53
D000911:Antibodies, Monoclonal; D010750:Phosphoproteins; D016159:Tumor Suppressor Protein p53