Genetic damage in Salmonella typhimurium by near-ultraviolet radiation. Lack of repair by plasmid pKM101.
Plasmid pKM101, whose mucA and B genes endow cells with enhanced mutation frequency and enhanced resistance to far-ultraviolet radiation (FUV) (254 nm), had no influence on these properties when cells were damaged by near-ultraviolet radiation (NUV) (300-400 nm). Thus, NUV lesions did not lead to induction of SOS repair and subsequent expression of mucA and B genes on plasmid pKM101. Further, when cells were pre-irradiated with NUV and subsequently irradiated with FUV, there was a blockage of SOS repair, including the repair normally controlled by genes on pKM101.
D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D005798:Genes, Bacterial / Q000528:radiation effects*; D009154:Mutation; D010957:Plasmids / Q000528:radiation effects*; D012486:Salmonella typhimurium / Q000235:genetics / Q000528:radiation effects*; D013045:Species Specificity; D014466:Ultraviolet Rays