title: The basal levels of active and inactive plasma renin concentration in infancy and childhood.
abstract: Basal plasma renin activity, active and inactive plasma renin concentration were measured in 89 healthy recumbent children aged between 1 week and 16 years. A significant (P less than 0.001) age-related decrease for active (r = -0.60), inactive (r = -0.59) and total renin concentration (r = -0.66) was observed. After correction for the influence of age, active renin concentration correlated with plasma renin activity (r = 0.81), but not with inactive renin concentration (r = 0.18). The proportions of active and inactive renin were not related to age, and the overall percentage of inactive renin was 79%.
mesh_terms: D000293:Adolescent; D000375:Aging; D002648:Child; D002675:Child, Preschool; D004789:Enzyme Activation; D004792:Enzyme Precursors / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012016:Reference Values; D012083:Renin / Q000097:blood*
chemical_list: D004792:Enzyme Precursors; D012083:Renin