title: [Bioavailability of cyclophosphamide following oral administration in high doses].
abstract: Mean rate of absorption of cyclophosphamide after oral administration from studies in which the drug is given in doses of 0,7 g/m2 body surface both orally and intravenously to the same 18 tumor patients is 87.7% (s - 21.1%). The drug may be administered orally with good bioavailability at the high dose.
mesh_terms: D000328:Adult; D001682:Biological Availability; D003520:Cyclophosphamide / Q000097:blood* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D003520:Cyclophosphamide
vernacular_title: Untersuchungen zur Bioverfügbarkeit von Cyclophosphamid nach peroraler Applikation im hohen Dosisbereich.