title: The mechanism of action of estramustine.
mesh_terms: D000478:Alkylation; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003432:Cross-Linking Reagents / Q000494:pharmacology; D004247:DNA / Q000378:metabolism / Q000494:pharmacology; D004347:Drug Interactions; D004351:Drug Resistance; D004958:Estradiol / Q000378:metabolism; D004961:Estramustine / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D005260:Female; D006367:HeLa Cells / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D046911:Macromolecular Substances; D008297:Male; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology*; D051381:Rats; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000187:drug effects / Q000378:metabolism
chemical_list: D003432:Cross-Linking Reagents; D046911:Macromolecular Substances; D009588:Nitrogen Mustard Compounds; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D004961:Estramustine; D004958:Estradiol; D004247:DNA