Comparison of the efficacy and toxicity of acyclovir and of adenine arabinoside when combined with dilute betamethasone in herpetic disciform keratitis: preliminary results of a double-blind trial.
Acyclovir is an effective and relatively non-toxic antiviral agent which has recently been introduced for the treatment of herpes virus infections in man. When combined with dilute steroid, acyclovir heals herpetic disciform keratitis and preliminary results of a double-blind clinical trial suggest that it may be more effective and less toxic than adenine arabinoside in the treatment of this condition.
D000212:Acyclovir / Q000009:adverse effects / Q000627:therapeutic use*; D001623:Betamethasone / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003316:Corneal Diseases / Q000139:chemically induced; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D006801:Humans; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D014740:Vidarabine / Q000009:adverse effects / Q000627:therapeutic use*
D001623:Betamethasone; D014740:Vidarabine; D000212:Acyclovir