title: Penetration of ceftazidime into the cerebrospinal fluid of patients with and without evidence of meningeal inflammation.
abstract: The concentrations of ceftazidime in the serum and cerebrospinal fluid of patients with and without meningitis were measured at various times after a 2- or 3-g dose. At similar concentrations in serum, ceftazidime concentrations in cerebrospinal fluid at a given time were substantially lower in patients without meningitis (mean, 0.8 micrograms/ml) than in those with meningitis (mean, 22.6 micrograms/ml).
mesh_terms: D000328:Adult; D000368:Aged; D002442:Ceftazidime; D002511:Cephalosporins / Q000097:blood / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid*; D008875:Middle Aged
chemical_list: D002511:Cephalosporins; D002442:Ceftazidime