Effects on cardiac rhythm of premedication with atropine or glycopyrrolate.
The effect of the premedicants atropine and glycopyrrolate on the cardiac dysrhythmic response to instrumentation and intubation was investigated. No significant increase in cardiac dysrhythmias such as bradycardia, atrial and ventricular extrasystoles was found (P greater than 0,01), but a significant increase in tachycardia occurred during induction (P less than 0,05) and intubation (P less than 0,01).
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D001285:Atropine / Q000009:adverse effects / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D006024:Glycopyrrolate / Q000009:adverse effects / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D011229:Preanesthetic Medication; D011759:Pyrrolidines / Q000494:pharmacology*
D011759:Pyrrolidines; D001285:Atropine; D006024:Glycopyrrolate