title: Detection of drugs in saliva of impaired drivers.
abstract: This study examined the feasibility of detecting drugs using saliva samples obtained from impaired drivers. Screening procedures on 1- to 2-mL samples were for cannabinoids, volatiles, benzodiazepines, and other acidic/neutral/basic drugs. Methodology consisted of enzyme multiple immunoassay technique (EMIT) and temperature programmed gas chromatography with confirmation by gas chromatography/mass spectrometry (GC/MS). Fifty-six samples were obtained from drivers arrested for suspicion of impaired driving. Other than alcohol, the major drugs detected were cannabinoids and diazepam. Cocaine was found in one case.
mesh_terms: D001334:Automobile Driving; D001569:Benzodiazepines / Q000032:analysis*; D002186:Cannabinoids / Q000032:analysis*; D002849:Chromatography, Gas; D003042:Cocaine / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D013058:Mass Spectrometry; D012463:Saliva / Q000032:analysis*; D019966:Substance-Related Disorders / Q000175:diagnosis*; D014835:Volatilization
chemical_list: D002186:Cannabinoids; D001569:Benzodiazepines; D003042:Cocaine