Tolerability and efficacy of a slow-release indomethacin tablet in ankylosing spondylitis.
The efficacy and tolerability of a new formulation of slow-release indomethacin tablet was compared in a double-blind cross-over manner with a conventional indomethacin capsule in 30 patients with ankylosing spondylitis. Gastrointestinal side-effects and dizziness were less frequent during the slow-release tablet period than during the capsule period.
D000328:Adult; D002214:Capsules; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004361:Drug Tolerance; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000188:drug therapy*
D002214:Capsules; D003692:Delayed-Action Preparations; D007213:Indomethacin