Breast-milk radioactivity after a Tc-99m DTPA aerosol/Tc-99m MAA lung study.
Measurements were made of the concentration of Tc-99m activity in samples of breast milk following an administration of Tc-99m DTPA aerosol for a lung ventilation image and one of Tc-99m MAA for lung perfusion. The activity was 222 nCi/ml of milk (8.2 kBq/ml) at 2 hr after the MAA injection, and it was found to be excreted exponentially with an effective half-life of 4.6 hr. There was a small incorporation of Tc-99m into breast-milk protein. We conclude that the combined use of these two Tc-99m agents did not indicate the interruption of breast feeding beyond 24 hr after administration of the MAA, and that for an aerosol ventilation study alone, breast feeding need not be interrupted for more than 4 hr after the test.
D000328:Adult; D000336:Aerosols; D001942:Breast Feeding; D005260:Female; D006207:Half-Life; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008895:Milk, Human / Q000528:radiation effects*; D004369:Pentetic Acid; D011851:Radioactivity; D011877:Radionuclide Imaging; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors
D000336:Aerosols; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate