[Immunochemical determination of DNA damage induced by high doses of ionizing radiation].
It was shown by the immunochemical method that DNA of X-irradiated E. coli cells of a radiosensitive mutant ABA88uvr A6 can react with the antiserum to thymine dimers which, in all appearance, are induced by ionizing radiation in bacterial DNA. The number of thymine dimers in DNA of E. coli AB1886uvr A6 increased with the dose increase. No dimers were detected in radioresistant cells of M. radioproteolyticus probably due to the effective excision thereof.
D004269:DNA, Bacterial / Q000032:analysis / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004926:Escherichia coli / Q000032:analysis / Q000528:radiation effects*; D007120:Immunochemistry; D008837:Micrococcus / Q000032:analysis / Q000528:radiation effects*; D011740:Pyrimidine Dimers / Q000032:analysis / Q000528:radiation effects; D011836:Radiation Tolerance
D004269:DNA, Bacterial; D011740:Pyrimidine Dimers
Opredelenie immunokhimicheskim metodom povrezhdeniĭ, voznikaiushchikh v DNK v rezul'tate deĭstviia vysokikh doz ioniziruiushcheĭ radiatsii.