[Microcirculation and inflammation].
On the basis of the literature analysis and own observations the author concludes that the process of inflammation involves all the components of the microcirculatory bed and the endothelial lining: arterioles, blood precapillaries, capillaries, postcapillaries, venules, lymph capillaries, systems of the interstitial tissue channels as well as the connective tissue rich in hyaluronic acid and proteoglycans. The emergence of all cardinal signs of inflammation is associated with damage of different components of the microcirculatory bed. Intensive peroxidation of lipids ("oxidative stress") was observed in the focus of inflammation. Microcirculatory disorders in the inflammation focus are always synchronously accompanied by activation of blood plasma protein systems: coagulation, anticoagulation, kinin, complementary.
D000818:Animals; D001692:Biological Transport; D001777:Blood Coagulation; D001792:Blood Platelets / Q000502:physiology; D002199:Capillary Permeability; D004487:Edema / Q000503:physiopathology; D005609:Free Radicals; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology*; D008054:Lipid Peroxides / Q000096:biosynthesis; D008208:Lymphatic System / Q000503:physiopathology*; D008264:Macrophages / Q000502:physiology; D008833:Microcirculation / Q000503:physiopathology*; D009504:Neutrophils / Q000502:physiology; D010447:Peptide Hydrolases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats
D005609:Free Radicals; D008054:Lipid Peroxides; D011506:Proteins; D010447:Peptide Hydrolases
Mikrotsirkuliatsiia i vospalenie.