title: Comparison of nitrazepam and zopiclone in psychiatric patients.
abstract: This investigation compares the effects of single and double doses of nitrazepam (5 and 10 mg) and zopiclone (7.5 and 15 mg) and placebo for 1 night in 40 psychiatric patients. The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being best adapted to the type of patients included in the study.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D053961:Azabicyclo Compounds; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008297:Male; D008568:Memory / Q000187:drug effects; D001523:Mental Disorders / Q000150:complications*; D008875:Middle Aged; D009567:Nitrazepam / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D012890:Sleep / Q000187:drug effects; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone; D009567:Nitrazepam