[Incidence of decreased insulin sensitivity in obese patients].
A method has been presented for the detection of organism sensitivity to insulin, involving simultaneous administration of insulin (intravenously) and the solution of partially hydrolized starch (orally), followed by the determination of the blood sugar level after 1 and 2 hours. By means of this method sensitivity to insulin was established in 55 patients with obesity and 16 healthy humans. It was found that sensitivity to insulin among patients with obesity of the I-III stages is lowered in 33% of cases and in subjects with the IV stage of the disease in 62%. The results of the determination of sensitivity to exogenous insulin correlate with IRI level in these patients.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood / Q000517:prevention & control; D005260:Female; D005767:Gastrointestinal Diseases / Q000097:blood; D006801:Humans; D007328:Insulin; D007333:Insulin Resistance; D008297:Male; D008722:Methods; D008875:Middle Aged; D009765:Obesity / Q000097:blood*
D001786:Blood Glucose; D007328:Insulin
Issledovanie chastoty snizheniia chuvstvitel'nosti k insulinu u bol'nykh ozhireniem.