A multicentre comparison of piroxicam and indomethacin in acute soft tissue sports injuries.
One hundred and five patients suffering from sport-associated soft tissue injuries were included in a randomized controlled trial comparing the efficacy and side-effects of piroxicam and indomethacin. Patients were treated for 7 days. Both groups showed a similar degree of improvement in joint tenderness, swelling and pain. Eighty-eight per cent of patients on piroxicam showed a marked or moderate improvement in their injury at the end of the trial and 79% of indomethacin-treated patients. Approximately 50% of patients in both groups resumed full activity within 7 days. One patient, in the indomethacin group, was withdrawn from treatment due to a side-effect.
D001265:Athletic Injuries / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004487:Edema / Q000188:drug therapy; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use*; D007596:Joints / Q000293:injuries*; D008297:Male; D010146:Pain / Q000188:drug therapy; D010349:Patient Compliance; D010894:Piroxicam; D011897:Random Allocation; D013843:Thiazines / Q000009:adverse effects / Q000627:therapeutic use*
D013843:Thiazines; D010894:Piroxicam; D007213:Indomethacin