Mutagenicity of coal-pyrolyzed products and their photochemical reaction products with nitrogen oxides in Salmonella typhimurium TA98 and TA100.
The chemical class separation of coal-pyrolyzed products and the photochemical reaction of these fractions with nitrogen oxides in the experimental chamber, and the application of a short-term mutagenicity test were investigated. The altered products from the fraction hydroxy polycyclic aromatic compounds in a simulated atmosphere containing a small volume of nitrogen oxides under irradiation with a xenon lamp were the most potent mutagenic fraction among all the fractions tested against Salmonella typhimurium, both TA98 and TA100, with or without S9.
D000818:Animals; D001711:Biotransformation; D003031:Coal; D006358:Hot Temperature; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens; D009154:Mutation; D009589:Nitrogen Oxides / Q000633:toxicity*; D010777:Photochemistry; D012486:Salmonella typhimurium / Q000187:drug effects; D013045:Species Specificity
D003031:Coal; D009153:Mutagens; D009589:Nitrogen Oxides