Evidence from peptide mapping for a human renin zymogen.
Data obtained from peptide mapping of the active and inactive forms of human renin show that there are extensive regions of common sequence in the two forms of the enzyme, and are consistent with the hypothesis that inactive renin is a renin zymogen.
D002851:Chromatography, High Pressure Liquid; D004591:Electrophoresis, Polyacrylamide Gel; D004792:Enzyme Precursors / Q000302:isolation & purification; D006801:Humans; D007672:Kidney Cortex / Q000201:enzymology; D008970:Molecular Weight; D010446:Peptide Fragments / Q000032:analysis; D012083:Renin / Q000302:isolation & purification
D004792:Enzyme Precursors; D010446:Peptide Fragments; D012083:Renin