Case problems in bone marrow transplantation. I. Graft failure in aplastic anemia: its biology and treatment.
An unusual case of graft failure following bone marrow transplantation for aplastic anemia is reported in which the patient had delayed and incomplete recovery of hematopoiesis despite documentation of sustained engraftment. The pathophysiology of graft failure following bone marrow transplantation is discussed and recent advances in pretransplant immunosuppressive therapy to prevent graft rejection are reviewed.
D000293:Adolescent; D000741:Anemia, Aplastic / Q000628:therapy*; D016026:Bone Marrow Transplantation; D005260:Female; D006084:Graft Rejection; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007165:Immunosuppression Therapy; D011247:Pregnancy; D014184:Transplantation, Homologous / Q000009:adverse effects*; D014430:Twins, Monozygotic
D006680:HLA Antigens