Pharmacologic trials in the treatment of cerebellar tremor.
We studied the effect of long-term administration of propranolol hydrochloride and isoniazid and the acute action of ethyl alcohol on cerebellar tremor in patients with multiple sclerosis and primary cerebellar degeneration in a placebo-controlled double-blind crossover test. None of the drugs decreased the severity of either static or kinetic cerebellar tremors.
D000328:Adult; D002526:Cerebellar Diseases / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D000431:Ethanol / Q000008:administration & dosage*; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy; D011433:Propranolol / Q000008:administration & dosage*; D014202:Tremor / Q000188:drug therapy*
D000431:Ethanol; D011433:Propranolol; D007538:Isoniazid