Urography with iohexol. Comparison with metrizoate and iodamide.
Comparisons of the non-ionic medium iohexol with the ionic media Na-Ca-Mg metrizoate and meglumine iodamide, were performed in two separate trials. The difference in diagnostic properties between the media was not significant. There was a significantly lower frequency of subjective sensations after iohexol than after metrizoate, whereas the difference between iohexol and iodamide in this respect was small. Regarding other adverse reactions there was a small advantage in favour of iohexol compared with metrizoate, whereas iohexol caused significantly less adverse reactions than iodamide.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000633:toxicity; D004311:Double-Blind Method; D004342:Drug Hypersensitivity / Q000209:etiology; D004487:Edema / Q000139:chemically induced; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology; D007451:Iodamide / Q000633:toxicity; D007463:Iodobenzoates; D007472:Iohexol; D008297:Male; D008794:Metrizoic Acid / Q000633:toxicity; D008875:Middle Aged; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000633:toxicity; D014567:Urography; D014581:Urticaria / Q000139:chemically induced
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D007451:Iodamide; D008794:Metrizoic Acid