title: Insulin wastage in ambulant practice.
abstract: The total insulin consumption in 162 insulin-requiring diabetic patients was calculated from the prescriptions of purchased insulin for 1979-80. The mean daily consumption was 58.6 U, whereas the actual dose injected was 41.7 U. A mean of 1.9 doses was injected daily, which yields a loss per dose of 8.9 U (SD +/- 7.9). The dose loss was independent of age and sex and only marginally dependent on insulin dose. Visual impairment increased the loss. From a direct study of 101 patients while drawing their usual morning dose of insulin into the syringe, the following major factors underlying insulin wastage emerged: (1) expulsion of surplus insulin into the air instead of into the vial, when adjustment of the insulin dose is made; (2) use of syringes with a separate needle instead of new low-dead-space syringes; and (3) unnecessary use of 2-ml syringes for doses of insulin less than or equal to 40 U (less than or equal to 1 ml).
mesh_terms: D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D006801:Humans; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D012646:Self Administration; D013548:Sweden
chemical_list: D007328:Insulin