Unusual immunofluorescent pattern in leishmaniasis (oriental sore).
Skin lesions of acute cutaneous leishmaniasis were found in three healthy men. A smear for Leishman-Donovan (LD) bodies as well as histopathologic studies of the lesions confirmed the diagnosis. Direct immunofluorescent studies of the lesions revealed deposits of immunoglobulins and complement in dermoepidermal junctions and fibrinogen in dermal blood vessels.
D000208:Acute Disease; D000328:Adult; D003176:Complement C3 / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007896:Leishmaniasis / Q000276:immunology*; D008297:Male
D003176:Complement C3; D007074:Immunoglobulin G; D007075:Immunoglobulin M