title: [Neurosyphilis resistant to high doses of penicillin: report of a case].
abstract: A case of neurosyphilis that got worse despite several therapeutical trials with high doses of penicillin is described. The clinical condition was stabilized and cerebrospinal fluid data normalized following treatment with chloramphenicol.
mesh_terms: D000293:Adolescent; D002701:Chloramphenicol / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D009494:Neurosyphilis / Q000188:drug therapy*; D010403:Penicillin Resistance; D010406:Penicillins / Q000134:cerebrospinal fluid / Q000494:pharmacology / Q000627:therapeutic use*; D014210:Treponema pallidum / Q000187:drug effects
chemical_list: D010406:Penicillins; D002701:Chloramphenicol
vernacular_title: Neurossífilis resistente a altas doses de penicilina: registro de um caso.