Homologies in the structures of bull seminal plasma acrosin inhibitors and comparison with other homologous proteinase inhibitors of the Kazal type.
After determination of the amino-acid sequence of a further acrosin inhibitor isolated from bull seminal plasma, the primary structures of the three seminal inhibitors known so far were compared with other homologous structures of protein-protein inhibitors. From the matrix of minimal base changes, a high divergence in the evolution of the seminal inhibitors can be seen. Inhibitors from bull seminal plasma show even a higher degree of relationship to dog submandibular gland inhibitor domain II and the 3rd domain of quail ovomucoid than to acrosin inhibitor from boar seminal plasma.
D000176:Acrosin / Q000037:antagonists & inhibitors*; D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D004285:Dogs; D006801:Humans; D008297:Male; D011480:Protease Inhibitors / Q000302:isolation & purification*; D011784:Quail; D012661:Semen / Q000201:enzymology*; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013552:Swine; D014359:Trypsin Inhibitor, Kazal Pancreatic; D014361:Trypsin Inhibitors
D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; D014359:Trypsin Inhibitor, Kazal Pancreatic; D000176:Acrosin