Multiple cerebral hemorrhages following chymopapain chemonucleolysis. Case report.
A case of multiple cerebral hemorrhages following chymopapain chemonucleolysis is reported. The authors believe the probable etiology was intrathecal extravasation of chymopapain after injection of the drug into a lumbar disc space.
D000328:Adult; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000601:surgery; D002917:Chymopapain / Q000009:adverse effects*; D010450:Endopeptidases / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013122:Spinal Diseases / Q000188:drug therapy
D010450:Endopeptidases; D002917:Chymopapain