Fatal, low renin hypertension associated with a disturbance of cortisol metabolism.
A 5 month old boy died after fever, persistently raised blood pressure, and hypokalaemia. A disorder of cortisol metabolism caused by 11 beta-hydroxysteroid dehydrogenase deficiency was detected retrospectively.
D042842:11-beta-Hydroxysteroid Dehydrogenases; D000450:Aldosterone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D006913:Hydroxysteroid Dehydrogenases / Q000172:deficiency*; D006973:Hypertension / Q000209:etiology*; D007223:Infant; D008297:Male; D012083:Renin / Q000097:blood
D000450:Aldosterone; D006913:Hydroxysteroid Dehydrogenases; D042842:11-beta-Hydroxysteroid Dehydrogenases; D012083:Renin; D006854:Hydrocortisone