title: [Effectiveness of combined and complex treatment of patients with operable cancer of the rectum].
abstract: Three hundred and eleven cases of rectal cancer received treatment according to the protocol of a cooperative randomized study. Preoperative irradiation improved three-year survival rates, particularly, in node-negative patients. In node-positive patients, frequency of relapse dropped from 30.0 +/- 8.5 to 5.7 +/- 3.9% when surgical treatment was supplemented by pre- and postoperative irradiation or drug therapy.
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*
chemical_list: D003037:Cobalt Radioisotopes; D005472:Fluorouracil
vernacular_title: Effektivnost' kombinirovannogo i kompleksnogo lecheniia bol'nykh operabel'nym rakom priamoĭ kishki.