Immunohistochemical localization of corticotropin releasing factor (CRF) in the hypothalamus of the squirrel monkey, Saimiri sciureus.
Corticotropin releasing factor immunoreactive (CRF-IR) neuronal cell bodies and fibers have been localized in both the paraventricular and supraoptic nuclei of the hypothalamus of the squirrel monkey. The major projection from these nuclei is to the median eminence and neural stem. A few CRF-IR fibers were found in the dorsal pars nervosa primarily adjacent to the pars intermedia. A rostral projection of CRF-IR fibers is associated with the suprachiasmatic nucleus and continues to septal areas. A caudally projecting bundle of fibers was observed entering the midbrain in neuropil adjacent to the aqueduct. The location of CRF-IR components is also compared with those containing vasopressin (AVP).
D000818:Animals; D001127:Arginine Vasopressin / Q000032:analysis; D003346:Corticotropin-Releasing Hormone / Q000032:analysis*; D005260:Female; D006651:Histocytochemistry; D007031:Hypothalamus / Q000032:analysis*; D007124:Immunoenzyme Techniques; D008297:Male; D009412:Nerve Fibers / Q000032:analysis; D009474:Neurons / Q000032:analysis; D010286:Paraventricular Hypothalamic Nucleus / Q000032:analysis; D012453:Saimiri; D013495:Supraoptic Nucleus / Q000032:analysis; D014018:Tissue Distribution
D001127:Arginine Vasopressin; D003346:Corticotropin-Releasing Hormone