Effect of seminal plasmin on rRNA synthesis in Saccharomyces cerevisiae.
Seminal plasmin, the highly basic, antimicrobial protein, isolated from bull semen, was found to inhibit the transcription of ribosomal RNA in yeast. Protein synthesis and processing of rRNA remained unaffected. Seminal plasmin appears to be useful for studies of the biosynthesis of yeast rRNA in pulse-chase experiments.
D000890:Anti-Infective Agents / Q000494:pharmacology*; D007700:Kinetics; D009154:Mutation; D009694:Nucleic Acid Precursors / Q000378:metabolism; D011506:Proteins / Q000494:pharmacology*; D012322:RNA Precursors; D012331:RNA, Fungal / Q000096:biosynthesis; D012335:RNA, Ribosomal / Q000096:biosynthesis* / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029607:Seminal Vesicle Secretory Proteins; D014158:Transcription, Genetic / Q000187:drug effects; D014498:Uracil / Q000378:metabolism
D000890:Anti-Infective Agents; D009694:Nucleic Acid Precursors; D011506:Proteins; D012322:RNA Precursors; D012331:RNA, Fungal; D012335:RNA, Ribosomal; D029607:Seminal Vesicle Secretory Proteins; D014498:Uracil