title: Kinetics of methylation in Escherichia coli K-12.
abstract: Newly synthesized DNA is undermethylated in E. coli K-12. The amount of N6-methyl deoxyadenylic acid in labeled DNA varied from 0.3 mol% of total adenine for a 2-min pulse to 1.7 mol% for DNA that was labeled for more than two generations.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004269:DNA, Bacterial / Q000302:isolation & purification / Q000378:metabolism*; D003838:Deoxyadenine Nucleotides / Q000032:analysis*; D004926:Escherichia coli / Q000378:metabolism*; D007700:Kinetics; D008745:Methylation
chemical_list: D004269:DNA, Bacterial; D003838:Deoxyadenine Nucleotides; C041895:N(6)-methyl-3'-deoxy-5'-adenylic acid