Molecular aspects of growth factor action: receptors and intracellular signals.
An increasing number of factors have been described which influence the proliferative responses of normal and neoplastic cells. A review of such moieties, their occurrence and possible mechanisms of their action and interaction is presented together with a discussion of their potential importance in the genesis and progression of neoplasms.
D000818:Animals; D002455:Cell Division; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D004815:Epidermal Growth Factor / Q000378:metabolism; D005246:Feedback; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D051379:Mice; D008934:Mitogens / Q000378:metabolism; D015240:Phorbol 12,13-Dibutyrate; D010703:Phorbol Esters / Q000378:metabolism; D051381:Rats; D011955:Receptors, Drug / Q000378:metabolism / Q000502:physiology*
D006133:Growth Substances; D008934:Mitogens; D010703:Phorbol Esters; D011955:Receptors, Drug; D015240:Phorbol 12,13-Dibutyrate; D004815:Epidermal Growth Factor