title: Developments in management of the newborn foal in respiratory distress 2: Treatment.
abstract: New developments in therapy for foals in respiratory distress are discussed. Therapy is based on preservation of the foal's life by maintenance of a patent airway, resuscitation with fluids and warmth, provision of humidified oxygen to raise the fractional concentration of inspired oxygen sufficient to avoid hypoxia and provision of ventilatory support when hypercapnia becomes critical. Ventilatory support described includes assisted and controlled ventilation, positive end expiratory pressure, continuous positive airway pressure and intermittent mandatory ventilation. The aims of these techniques are discussed together with their associated indications, disadvantages and complications. Secondary therapy includes coupage, airway hygiene, drug therapy and stress management. Knowledge of equine neonatology is limited in comparison with human neonatology. More information in basic physiology and pharmacology relating to equine neonatology is needed and the efficacy of various modes of therapy must be evaluated.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D006801:Humans; D007040:Hypoventilation / Q000628:therapy / Q000662:veterinary; D000860:Hypoxia / Q000628:therapy / Q000662:veterinary; D007231:Infant, Newborn; D010102:Oxygen Inhalation Therapy / Q000662:veterinary; D012121:Respiration, Artificial / Q000662:veterinary; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy / Q000662:veterinary*; D012138:Respiratory Therapy / Q000009:adverse effects / Q000662:veterinary*; D012151:Resuscitation / Q000662:veterinary