Gastric emptying, glucose tolerance and associated hormonal changes in heroin addiction.
The gastric emptying rate of 8 heroin-dependent males was measured by means of a radioactive isotope method. A simultaneous oral glucose tolerance test was carried out. The glucose response showed a low, flat curve with a delayed peak, and increased secretion of insulin and growth hormone occurred. As the gastric emptying rate proved to be normal the observed metabolic abnormalities are not due to the effect of heroin on the gastro-intestinal tract, but must be attributed to some other effect of chronic heroin administration.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005746:Gastric Emptying / Q000187:drug effects*; D005951:Glucose Tolerance Test; D013006:Growth Hormone / Q000097:blood; D006556:Heroin Dependence / Q000097:blood*; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D008297:Male
D001786:Blood Glucose; D006728:Hormones; D007328:Insulin; D013006:Growth Hormone; D006854:Hydrocortisone