title: [Treatment of hyperprolactinemic amenorrhea by pulsatile administration of gonadotropin-releasing hormone].
abstract: Two patients with hyperprolactinemic secondary amenorrhoea were treated with gonadotropin releasing hormone (GnRH). Both desired children and had an incompatibility to treatment with Dopamin agonists (Zyklomat). Both patients ovulated and had regular follicular maturation in spite of rising prolactin levels. The pregnancies occurred in the first treatment cycles. The pulsatile intravenous administration of GnRH is apparently a viable alternative plan of management in patients with a moderate hyperprolactinemia and incompatibility to Dopamine agonists to the treatment with gonadotropins which was in use up to now.
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy*; D001831:Body Temperature; D005260:Female; D006062:Gonadotropins; D006801:Humans; D010060:Ovulation; D010906:Pituitary Hormone-Releasing Hormones / Q000008:administration & dosage*; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*
chemical_list: D006062:Gonadotropins; D010906:Pituitary Hormone-Releasing Hormones; D011388:Prolactin
vernacular_title: Behandlung der hyperprolaktinämischen Amenorrhoe durch pulsatile Gabe von Gonadotropin-Releasing-hormon.