Evaluation of the patency rate of fibrous microvascular polyurethane prostheses after implantation in the rat aorta.
Two types of fibrous polyurethane prostheses with different compliances were implanted into the rat aorta with interrupted sutures and a running suture line. Excluding two technical failures, one unexplained death, and three infected prostheses, both groups (n = 21) showed a patency rate of 100%, up to 6 months after implantation. Rapid reendothelialisation occurred, and a stable neo-intima was formed. Compliance of the prostheses, as well as the suture technique used, has proven to be an unimportant factor in the rat aorta model, probably due to the low magnitude of the pulsations of the rat aorta. The experience of the surgeon with microsurgical techniques seems to be an underestimated factor in determining patency rates of microvascular prostheses.
D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery* / Q000648:ultrastructure; D001807:Blood Vessel Prosthesis; D004548:Elasticity; D005500:Follow-Up Studies; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008855:Microscopy, Electron, Scanning; D008866:Microsurgery / Q000379:methods*; D011140:Polyurethanes; D051381:Rats; D011919:Rats, Inbred Strains; D013499:Surface Properties; D013536:Suture Techniques; D013718:Tensile Strength; D013997:Time Factors
D011140:Polyurethanes