Immunoglobulins as targeting agents for liposome encapsulated drugs.
Recent literature dealing with the immunoglobulin-liposome combination as a tool for drug targeting is reviewed. Mechanisms for binding of immunoglobulins to liposomes are discussed. Results obtained so far by using this concept both to induce specific liposome-cell interactions in in vitro cell cultures and to target drug containing liposomes to selected tissues in animal studies are evaluated.
D002626:Chemistry, Pharmaceutical; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage*; D008081:Liposomes / Q000008:administration & dosage*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D011485:Protein Binding
D007136:Immunoglobulins; D008081:Liposomes; D004364:Pharmaceutical Preparations