title: [Experimental study of the immunogenicity of a monopreparation of Klebsiella pneumoniae antigen complex and its association with Staphylococcus, Proteus and Escherichia coli antigens].
abstract: The study carried out in mice with experimental Klebsiella sepsis has revealed that Staphylococcus, Proteus and E. coli antigenic complexes used as monovaccines ensure the protection of a definite percentage of the animals from K. pneumoniae infection. The mixture of these 3 preparations possesses a higher protective potency. The immunogenic potency of K. pneumoniae antigenic complex used as a component of combined vaccines with 2 or 4 components has proved to be sufficiently high and not inferior to the potency of K. pneumoniae monovaccine.
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001428:Bacterial Vaccines / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D004353:Drug Evaluation, Preclinical; D004926:Escherichia coli / Q000276:immunology*; D007114:Immunization; D007710:Klebsiella Infections / Q000517:prevention & control; D007711:Klebsiella pneumoniae / Q000276:immunology*; D051379:Mice; D011511:Proteus / Q000276:immunology*; D013210:Staphylococcus / Q000276:immunology*; D013997:Time Factors
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines
vernacular_title: Eksperimental'noe izuchenie immunogennosti monopreparata antigennogo kompleksa klebsielly pnevmonii i ego assotsiatsieĭ s antigenami stafilokokka, proteia i kishechnoĭ palochki.