title: [Urea as an antimicrobial and dehydration agent for the local treatment of suppurative surgical infection].
abstract: The 30% solution of urea is found to be an effective quick-acting means against gram-positive and gram-negative pyogenic microflora. Microorganisms discharged from purulent foci of patients were sensitive to the drug in 100% of cases. The local application of the 30% urea solution as irrigation used in 156 patients with pyo-surgical infection has shown the drug to be well endured by the patients. It has no side effects. The purulent process can be cupped off 1,5-1,7 times quicker.
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003890:Desiccation; D005597:Fractures, Open / Q000150:complications / Q000188:drug therapy; D006801:Humans; D006982:Hypertonic Solutions; D010019:Osteomyelitis / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014508:Urea / Q000627:therapeutic use*; D014946:Wound Infection / Q000188:drug therapy*
chemical_list: D000891:Anti-Infective Agents, Local; D006982:Hypertonic Solutions; D014508:Urea
vernacular_title: Mochevina kak antimikrobnoe i degidratatsionnoe sredstvo dlia mestnogo lecheniia pri gnoĭno-khirurgicheskoĭ infektsii.