Demineralized bone-matrix-induced osteogenesis.
A review of the literature on bone formation induced by demineralized bone and dentin indicates that: there is considerable interest in the biology and applied science of osteoinduction; the technology has been developed, but it varies in detail from one laboratory to another because of specific and individual objectives; and the accumulated evidence supports the concept of cartilage and bone cell differentiation induced by a unique bone morphogenetic protein (BMP).
D000818:Animals; D001857:Bone Matrix / Q000187:drug effects / Q000502:physiology*; D019485:Bone Morphogenetic Proteins; D002417:Cattle; D002454:Cell Differentiation; D003648:Decalcification Technique; D003804:Dentin / Q000187:drug effects / Q000502:physiology; D006133:Growth Substances / Q000494:pharmacology; D006648:Histocompatibility; D006801:Humans; D010012:Osteogenesis; D011208:Powders; D011506:Proteins / Q000494:pharmacology; D011817:Rabbits; D013242:Sterilization / Q000379:methods
D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D011208:Powders; D011506:Proteins