Immunolocalization of a sperm membrane protein in human male reproductive organs.
A monoclonal antibody that induces agglutination of human sperm was used to localize the interacting antigen in various tissues by indirect immunofluorescence. The antibody localized to the immature sperm and Sertoli cells of the seminiferous tubules, simple cuboidal epithelial cells of the rete testis, and the columnar epithelial cells of the ductuli efferentes. The present results show that the interacting protein is found associated with germ cells undergoing spermatogenesis.
D000818:Animals; D000911:Antibodies, Monoclonal; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008970:Molecular Weight; D013073:Sperm Agglutination; D013094:Spermatozoa / Q000276:immunology*
D000911:Antibodies, Monoclonal; D008565:Membrane Proteins