[Significance of bacteremia in the development of immunological memory suppression in Shigella sonnei infection in mice].
Experiments on mice infected intraperitoneally with S. sonnei have revealed that the level of bacteriemia is directly related to the duration of the blocking of immunological memory constituting the basis of secondary humoral and cell-mediated immune response. The transfer of syngeneic splenocytes from immunized mice has demonstrated that virulent S. sonnei directly affect the immunological memory cells.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D004405:Dysentery, Bacillary / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007156:Immunologic Memory; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D018805:Sepsis / Q000276:immunology*; D012764:Shigella sonnei / Q000276:immunology; D013154:Spleen / Q000276:immunology
D000907:Antibodies, Bacterial
Znachenie bakteriemii v razvitii supressii immunologicheskoĭ pamiati pri infektsii Shigella sonnei u mysheĭ.