title: A miniature infuser for the pulsatile administration of LHRH.
abstract: This paper describes a compact, battery-powered infuser that is light, unobtrusive and simple to operate. A novel direct-drive method is used to deliver intermittent boluses of hormone at predetermined time intervals via a special prefilled syringe. Normal pregnancy rates were achieved in anovulatory women when infused with luteinising hormone releasing hormone (LHRH).
mesh_terms: D001698:Biomedical Engineering; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage*; D006801:Humans; D007263:Infusions, Parenteral / Q000295:instrumentation*
chemical_list: D007987:Gonadotropin-Releasing Hormone