[Immunomorphologic characteristics of the distribution of collagen types I, III, IV and V in normal intima and in atherosclerosis of the major arteries and aorta in man].
The distribution of collagen of the above types in normal intima, sites of its physiological thickening, lipid streaks, atherosclerotic plaques is studied by the immunoluminescent method. All collagen types at various proportions are found to be located in the subendothelial areas of intima. Besides that the IV and V collagen types are detected in the zone of endothelial basal membrane. The essential property of atherosclerotic plaques is the prevalence of rough fibrillar structures from interstitial collagen which do not occur normally.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001158:Arteries / Q000378:metabolism*; D001161:Arteriosclerosis / Q000378:metabolism*; D001485:Basement Membrane / Q000378:metabolism; D003094:Collagen / Q000378:metabolism*; D004727:Endothelium / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D006801:Humans; D008875:Middle Aged
D003094:Collagen
Immunomorfologicheskaia kharakteristika raspredeleniia kollagena I, III, IV, V tipov v normal'noĭ intime i pri ateroskleroze krupnykh arteriĭ i aorty cheloveka.