title: Physiological bases for new approaches to mechanical ventilation.
abstract: High frequency ventilatory (HFV) techniques offer potential advantages over conventional forms of mechanical ventilation in patients with diverse forms of respiratory insufficiency. In some respects, HFV challenges conventional physiologic concepts regarding gas transport in the lung. We review hypotheses regarding the mechanism of gas transport and provide a brief perspective on current clinical applications of these techniques.
mesh_terms: D006801:Humans; D011659:Pulmonary Gas Exchange; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods*; D012131:Respiratory Insufficiency / Q000503:physiopathology / Q000628:therapy