Adsorption of Escherichia coli onto insolubilized lauryl pyridinium iodide and its bacteriostatic action.
Insoluble lauryl pyridinium iodide [C12(50)] was synthesized as an antimicrobial agent. Escherichia coli cells were not killed by C12(50) but only adsorbed onto it. Though cells on C12(50) could not grow in nutrient agar, they possessed the ability to develop once they were liberated from C12(50). The adsorption of cells onto C12(50) was inhibited by iodide anions released from C12(50) itself. The ability of C12(50) to adsorb was decreased by the adsorbed cells, but C12(50) could be reactivated by washing with alkaline solutions. It was, therefore, suggested that this adsorption was mainly due to the electrostatic interaction between cells and C12(50). The adsorption of cells onto C12(50) was confirmed by scanning electron microscopy.
D000327:Adsorption; D004202:Disinfectants / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D007454:Iodides / Q000494:pharmacology; D011726:Pyridinium Compounds / Q000494:pharmacology*; D012995:Solubility
D004202:Disinfectants; D007454:Iodides; D011726:Pyridinium Compounds; C001524:Laurosept