Cellular senescence and atherosclerosis.
Most recent texts on atherosclerosis do not consider cellular senescence. Texts that do take this up often emphasize smooth muscle cells. This paper presents some evidence for the role of cellular senescence in atherogenesis, and points out that the cells of the intimal endothelium may be equally important in this respect.
D000328:Adult; D000368:Aged; D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000473:pathology; D002455:Cell Division; D002470:Cell Survival; D002999:Clone Cells / Q000166:cytology; D004727:Endothelium / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D008954:Models, Biological; D013314:Stress, Mechanical