Effects of hyperbaric oxygen and hyperbaric air on the survival of island skin flaps.
The effects of hyperbaric air and oxygen on skin survival were studied in acute 8 X 8 cm neurovascular island flaps in rats. Skin flaps treated with hyperbaric 8% oxygen (equivalent to room air at standard pressure) exhibited no improvement in skin survival. Skin flaps treated with hyperbaric air (21% oxygen) and hyperbaric 100% oxygen exhibited significant increases in survival.
D000388:Air; D000399:Air Pressure; D000818:Animals; D005069:Evaluation Studies as Topic; D005260:Female; D006085:Graft Survival; D006931:Hyperbaric Oxygenation; D051381:Rats; D011919:Rats, Inbred Strains; D016038:Skin Transplantation; D013524:Surgical Flaps