Clinical evaluation of amitraz for treatment of canine scabies.
A liquid concentrate formulation of amitraz (Mitaban: Upjohn) was used to topically treat 181 dogs with scabies, at an active drug level of 250 ppm, or 10.6 ml of concentrate in 2 gal water. After the dogs were clipped and bathed, the diluted medication was applied and allowed to dry on the animal. All treated dogs were clinically improved and 97.8% cured after a single treatment; 3 dogs required 2 treatments and 1 dog 3 treatments. Otodectes cynotis and Cheyletiella yasguri in several dogs were also cleared after 1 treatment. Mild, transient sedation occurred in 12.4% of treated dogs, with transient vomiting, increased appetite and diarrhea in less than 1%.
D000818:Animals; D002986:Clinical Trials as Topic; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D007306:Insecticides / Q000627:therapeutic use*; D008297:Male; D012532:Scabies / Q000188:drug therapy / Q000662:veterinary*; D014052:Toluidines / Q000627:therapeutic use*
D007306:Insecticides; D014052:Toluidines; C014983:amitraz