Ethnic differences in kidney graft survival.
Results of 73 first cadaveric donor renal transplants in Jerusalem between 1975 and 1980 are presented. There was a better 12-month graft survival in Arabs than in Jews (70.8% vs. 40.8%, P less than 0.035); however, 12-month patient survival was similar (83.3% vs. 85.7%). Acute rejection as the primary cause of graft loss occurred in 12.5% of the Arabs and 38.8% of the Jews (P less than 0.05). HLA-A, -B and -DR antigen-sharing was similar in both groups. Early acute rejection episodes had a poorer prognosis in Jews. Possible explanations for these findings are discussed, but the reason for the higher success rate in Arabs remains obscure.
D000293:Adolescent; D000328:Adult; D002648:Child; D005006:Ethnicity; D005260:Female; D006085:Graft Survival; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007557:Israel; D007585:Jews; D007668:Kidney; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens