Immunoelectrophoretic investigations in 55 patients with systemic amyloidosis.
Among 55 amyloidoses, the detection of a monoclonal protein (MP) led to the selection of 15 primary and 3 myeloma-associated types of amyloidosis. Therefore the presence of a MP gives evidence for an immunocytic amyloidosis. The lambda-light-chain nature of MP and the abundant production of free light-chains are two of the factors predisposing to the production of amyloid deposits (AL) in the course of immunocyte dyscrasias.
D000682:Amyloid / Q000145:classification; D000686:Amyloidosis / Q000145:classification* / Q000209:etiology / Q000276:immunology; D001536:Bence Jones Protein / Q000652:urine; D006801:Humans; D007122:Immunoelectrophoresis; D007124:Immunoenzyme Techniques; D009101:Multiple Myeloma / Q000150:complications; D009194:Myeloma Proteins / Q000145:classification
D000682:Amyloid; D009194:Myeloma Proteins; D001536:Bence Jones Protein