Fibronectin as an opsonic regulator of monocyte phagocytosis.
Experiments using human monocytes and the yeast Saccharomyces cerevisiae have shown that fibronectin is a major plasma opsonin. Further studies have shown that fibronectin promotes the ingestion as well as the adherence of micro-organisms. These observations are independent of the non-physiological concentrations of heparin used in other assay systems.
D005353:Fibronectins / Q000494:pharmacology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D009000:Monocytes / Q000187:drug effects / Q000276:immunology*; D009895:Opsonin Proteins / Q000276:immunology*; D010587:Phagocytosis / Q000187:drug effects*; D012441:Saccharomyces cerevisiae / Q000276:immunology
D005353:Fibronectins; D007074:Immunoglobulin G; D009895:Opsonin Proteins