title: [Fine needle aspiration of neck tumor. Application of cytological, bacteriological and hormonal examinations].
abstract: Aspiration of neck tumors with a fine needle combined with cytological, bacteriological and hormonal examinations greatly improved the accuracy of the differential diagnosis of the neck tumors. Fine needle aspiration cytology in 45 patients with thyroid tumor gave only 4% (1/25) false negative diagnosis and 0% (0/20) false positive diagnosis for carcinoma, whereas false negative and false positive diagnosis by palpation were 34% and 4%, respectively and those by soft tissue roentgenogram were 55% and 0%, respectively. Differential diagnosis of histological types of thyroid carcinoma was possible by cytology. Fine needle aspiration of cervical lymph nodes gave the diagnosis of malignant lymphoma, metastatic squamous cell carcinoma, adenocarcinoma or inflammatory changes. Bacterial culture from the aspirate yielded causative microorganism in 5 patients including 4 with tuberculosis. The specimens aspirated from thyroglossal duct cysts or branchial cysts showed specific appearance and cytological feature. The aspirate from a parathyroid cyst was watery clear and contained high amount of parathyroid hormone. Dark brown serous aspirate from extrathyroidal mass suggested metastatic lesion from occult papillary carcinoma of the thyroid in 2 patients. Demonstration of very high content of thyroglobulin of the aspirate determined by radioimmunoassay supported the diagnosis, which was confirmed later at surgery. This method has become a routine work in our out-patient clinic.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D001431:Bacteriological Techniques; D001707:Biopsy, Needle / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003581:Cytodiagnosis / Q000379:methods*; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis; D010281:Parathyroid Hormone / Q000032:analysis; D013959:Thyroid Diseases / Q000175:diagnosis; D013964:Thyroid Neoplasms / Q000175:diagnosis
chemical_list: D010281:Parathyroid Hormone