A cytoskeletal protein unique to lens fiber cell differentiation.
A chick lens urea-soluble polypeptide of estimated mol. wt. 49 000 daltons is unique to fiber cell differentiation and is a component of the beaded-chain filaments of the chick cytoskeleton. Antigenically related proteins are also present in the human and bovine lens. There is no similarity between this protein and actin as determined by immunological analysis and two-dimensional gel electrophoresis.
D000818:Animals; D000918:Antibody Specificity; D002417:Cattle; D002454:Cell Differentiation; D002645:Chickens; D003459:Crystallins / Q000032:analysis* / Q000276:immunology; D003599:Cytoskeleton / Q000032:analysis* / Q000648:ultrastructure; D004591:Electrophoresis, Polyacrylamide Gel; D005455:Fluorescent Antibody Technique; D006801:Humans; D007525:Isoelectric Focusing; D007908:Lens, Crystalline / Q000032:analysis* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron
D003459:Crystallins