title: Genetics of octanol and alpha-glycerophosphate dehydrogenases in the mosquito Aedes (Finlaya) togoi.
abstract: Genetic studies were performed on octanol dehydrogenase (EC 1.1.1.73) and alpha-glycerophosphate dehydrogenase (EC 1.1.1.8) in the mosquito Aedes (Finlaya) togoi by agar gel electrophoresis. The electrophoretic survey revealed two octanol dehydrogenase loci (Odh-1, Odh-2) and one alpha-glycerophosphate dehydrogenase locus (alpha-Gpdh) in this species. Five alleles were observed at the Odh-2 locus in seven laboratory strains, whereas the alpha-Gpdh locus was completely monomorphic in six of seven strains examined and the second allele at this locus was detected in only one strain at a frequency of 0.14. Both loci code for dimeric enzymes. Linkage studies on Odh-2 and alpha-Gpdh suggested that the gene arrangement and recombination units were Odh-2--(25.8)--M (sex locus)--(30.5)--s (strawcolored larva) and M--(25.6)--alpha-Gpdh--(15.4)--s. These results, together with linkage data previously reported, give the following gene linkage on the sex chromosome: Odh-2--Est-3 (carboxylesterase)--Acph (acid phosphatase)--M--alpha-Gpdh--s--Est-2 (carboxylesterase). The total map length of this arrangement is approximately 75 map units.
mesh_terms: D000330:Aedes / Q000201:enzymology* / Q000235:genetics; D000429:Alcohol Oxidoreductases / Q000235:genetics*; D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004587:Electrophoresis, Agar Gel; D008040:Genetic Linkage; D005993:Glycerolphosphate Dehydrogenase / Q000235:genetics*
chemical_list: D000429:Alcohol Oxidoreductases; D005993:Glycerolphosphate Dehydrogenase; C021902:octanol dehydrogenase