Identification and localization of antigens of the malaria parasite, Plasmodium falciparum, by immune precipitation.
Human immune sera from Thailand selectively immunoprecipitated P. falciparum (Kl isolate) [35S]methionine-labelled antigens with molecular weights of 85,000 and 200,000, the latter being specific to the schizont stage. Radioiodination using Iodogen and Na 125I failed to label parasite proteins located on the external surface of schizont-infected human red cells.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008288:Malaria / Q000209:etiology; D010963:Plasmodium falciparum / Q000254:growth & development / Q000276:immunology*
D000954:Antigens, Surface