Pulmonary bone-marrow embolisation after unfiltered autologous bone-marrow transplantation.
A 15-year-old girl had Ewing's sarcoma of the right scapula 1978 and was treated with local radiotherapy and adjuvant chemotherapy. She remained in complete remission until September 1982 when she developed a single pulmonary metastasis in the right lower lobe. She received a high dose of Melphalan twice, always followed by autologous bone-marrow transplantation. A segmental right lower lobectomy revealed haematopoietic bone-marrow tissue emboli within the alveolar capillaries and foreign body granulomatous lesions in the whole surgical specimen. No residual Ewing's sarcoma growth was seen.
D000293:Adolescent; D016026:Bone Marrow Transplantation; D001859:Bone Neoplasms / Q000628:therapy*; D005260:Female; D006801:Humans; D011655:Pulmonary Embolism / Q000209:etiology*; D012512:Sarcoma, Ewing / Q000628:therapy*; D012540:Scapula