title: Prospective randomized trials demonstrating the efficacy of adjuvant chemotherapy in adult patients with soft tissue sarcomas.
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005121:Extremities; D006258:Head and Neck Neoplasms / Q000188:drug therapy; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009316:National Institutes of Health (U.S.); D010865:Pilot Projects; D011897:Random Allocation; D012107:Research Design; D012509:Sarcoma / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014481:United States
chemical_list: D004317:Doxorubicin; D003520:Cyclophosphamide; D008727:Methotrexate