title: Efficacy of aztreonam in treatment of experimental syphilis in rabbits.
abstract: The efficacy of aztreonam (SQ 26,776) in the therapy of active syphilis infection was evaluated in the rabbit model. Aztreonam was effective in treating active syphilis at a dose of 25 mg/kg given intramuscularly twice daily for 10 days; doses of 2.5 and 0.25 mg/kg were not effective.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001398:Aztreonam; D008297:Male; D010401:Penicillin G Benzathine / Q000494:pharmacology; D011817:Rabbits; D013587:Syphilis / Q000188:drug therapy* / Q000382:microbiology; D014210:Treponema pallidum
chemical_list: D000900:Anti-Bacterial Agents; D001398:Aztreonam; D010401:Penicillin G Benzathine