title: Improving the production of monensin by Streptomyces cinnamonensis.
abstract: The production of monensin by Streptomyces cinnamonensis was increased by genetic improvement of the strain and by modification of cultivation conditions. The selection of a suitable strain and optimization of the fermentation process (temperature, aeration, addition of esters of oleic acid) resulted in a 30 fold increase of the monensin production.
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001431:Bacteriological Techniques; D005663:Furans / Q000096:biosynthesis*; D005786:Gene Expression Regulation; D008985:Monensin / Q000096:biosynthesis*; D013291:Streptococcus / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D005663:Furans; D008985:Monensin