Effects of freezing and freeze-drying on the biomechanical properties of rat bone.
The effects of various preservation techniques on the biomechanical properties of bone have been investigated in a rat model. Freezing of the specimens to -20 degrees C, -70 degrees C, and -196 degrees C did not adversely affect the strength of long bones tested in torsion or of vertebral bodies tested in compression. Freeze-drying did not markedly affect the compression properties of the vertebral specimens; however, it did produce a significant deleterious reduction in the torsional strength of the long bones.
D000818:Animals; D001696:Biomechanical Phenomena; D016025:Bone Transplantation; D001842:Bone and Bones / Q000502:physiology; D005612:Freeze Drying; D005615:Freezing; D009926:Organ Preservation; D051381:Rats; D011919:Rats, Inbred Strains