title: Effect of region assignment on relative renal blood flow estimates using radionuclides.
abstract: To determine the value of the initial phase of the Tc-99m DTPA renogram in the direct estimation of relative renal blood flow in dogs, the ratios of the slopes of renal time-activity curves were compared with the ratios of measured blood flow. Radionuclide results were dependent on region-of-interest (ROI) and background ROI assignment, and correlated well with measured relative flow only with a maximum renal outline region. Curve slope ratios correlated well with measured flow ratios with and without background correction, while 1- to 2-minute uptake ratios correlated well only when corrected for background.
mesh_terms: D000818:Animals; D004285:Dogs; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013667:Technetium; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors
chemical_list: D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate