Determination of the probability of self-renewal in haemopoietic stem cells: a puzzle.
This paper calls attention to anomalous behaviour of the spleen colony forming cell system, when quantitative measurements of the self-renewal probability of the CFU-S are attempted.
D000818:Animals; D016026:Bone Marrow Transplantation; D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D051379:Mice; D011336:Probability; D013154:Spleen / Q000166:cytology