title: [Diagnosis of complications of psychopharmacotherapy caused by drug allergy using the vesiculation test].
abstract: The use of the vesiculation test (VT) as a method of allergy diagnosis in a number of severe complications following psychopharmacotherapy of psychoses makes it possible to diagnose their allergic nature and thus to begin a purposeful treatment, preventing in this way a further development of the pathological process. Allergodiagnosis in such cases is of great practical value in view of the difficulties presented by the clinical diagnosis of the above states. In drug-induced complications, the VT shows a high degree of sensitization to a definite drug; in cases of the effective treatment of psychoses by psychopharmacologic drugs attended by no complications, there is a moderate elevation in VT intensity (immunological resistance corresponds to clinical resistance). These observations require further clarification through extensive clinical research and if confirmed they will assume practical significance in selecting the treatment method.
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects; D001714:Bipolar Disorder / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000097:blood*; D005260:Female; D006462:Hemolytic Plaque Technique; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy*; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000009:adverse effects*
chemical_list: D000928:Antidepressive Agents; D011619:Psychotropic Drugs
vernacular_title: Diagnostika oslozhneniĭ psikhofarmakoterapii, obuslovlennykh lekarstvennoĭ allergieĭ, metodom reaktsii vezikuloobrazovaniia.