title: Spontaneous healing and relief of pain in a patient with intractable vasculitic ulceration of the lower limb following an intravenous infusion of prostacyclin: a case report.
abstract: A case is reported of a patient with diabetes and rheumatoid arthritis who presented with vasculitic ulceration of the lower leg and foot. The ulceration was associated with severe pain and showed no sign of healing despite conservative treatment and skin grafting. At the time when amputation seemed inevitable an intravenous infusion of prostacyclin was given. There was a rapid and lasting relief of pain and the ulcerated area began to heal spontaneously.
mesh_terms: D011464:Epoprostenol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007871:Leg Ulcer / Q000188:drug therapy*; D008875:Middle Aged; D014657:Vasculitis / Q000188:drug therapy*
chemical_list: D011464:Epoprostenol