Immunohistochemical detection of the sex steroid-binding plasma protein in human mammary carcinoma cells.
A sex steroid-binding plasma protein-like antigen has been detected in human mammary carcinoma cells. A monospecific antiserum was used, and this protein was located mainly on the cytoplasmic membranes. These results are in agreement with a recent hypothesis according to which steroid hormones could be carried into cells by specific binding plasma proteins.
D000230:Adenocarcinoma / Q000276:immunology / Q000378:metabolism; D000936:Antigen-Antibody Complex; D001943:Breast Neoplasms / Q000276:immunology / Q000378:metabolism*; D002462:Cell Membrane / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D007122:Immunoelectrophoresis; D011247:Pregnancy; D012738:Sex Hormone-Binding Globulin / Q000032:analysis*
D000936:Antigen-Antibody Complex; D007106:Immune Sera; D012738:Sex Hormone-Binding Globulin