Dose fractionation effects in low dose rate irradiation of jejunal crypt stem cells.
Jejunal crypt survival after fractionated total body irradiation of C3H mice given at dose rates of 1.2 or 0.08 Gy/min was studied. The fractionation effect was more pronounced at the high dose rate than at the low dose rate. Analysis of the data according to the linear-quadratic survival curve model yielded an alpha/beta value at 1.2 Gy/min of 13.3 Gy and at 0.08 Gy/min of 96 Gy.
D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D007583:Jejunum / Q000528:radiation effects*; D051379:Mice; D008809:Mice, Inbred C3H; D013234:Stem Cells / Q000528:radiation effects*; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes