Blood groups and HLA antigens in paracoccidioidomycosis.
The frequencies of blood groups, Rh and HLA antigens were studied in a series of patients with paracoccidioidomycosis as well as in control subjects. Statistical analysis of the results showed that only 2 antigens (HLA-A9 and HLA-B13) had a significantly increased frequency among patients with paracoccidioidomycosis compared with healthy controls. Among patients with paracoccidioidomycosis antigen HLA-A9 was significantly more prevalent in progressive pulmonary forms of the disease than in patients with extra pulmonary involvement. These observations suggest that HLA-A9 may influence susceptibility to the mycosis as well as its course.
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D000368:Aged; D003105:Colombia; D004198:Disease Susceptibility; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059908:HLA-B13 Antigen; D006801:Humans; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000097:blood / Q000276:immunology*; D010641:Phenotype; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D006680:HLA Antigens; D015234:HLA-A Antigens; C037709:HLA-A9 antigen; D015235:HLA-B Antigens; D059908:HLA-B13 Antigen; D012204:Rh-Hr Blood-Group System