Mutagenic studies on the insecticide Metasystox-R with different genetic systems.
The insecticide Metasystox-R was tested for mutagenic activity by a multiple bioassay. Its potential ability to induce gene mutation in Salmonella, micronuclei formation in mice, and sister-chromatid exchange (SCE) in human lymphocytes was evaluated. The insecticide induced detectable genotoxic effects in these tests. The results support the view that the insecticide is genotoxic.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000633:toxicity; D002467:Cell Nucleus / Q000187:drug effects; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D008214:Lymphocytes / Q000166:cytology; D051379:Mice; D016685:Mitomycin; D008937:Mitomycins / Q000633:toxicity; D009152:Mutagenicity Tests / Q000379:methods; D009153:Mutagens; D009154:Mutation; D009943:Organophosphorus Compounds / Q000633:toxicity*; D009946:Organothiophosphorus Compounds; D012486:Salmonella typhimurium / Q000187:drug effects; D012854:Sister Chromatid Exchange / Q000187:drug effects
D000903:Antibiotics, Antineoplastic; D007306:Insecticides; D008937:Mitomycins; D009153:Mutagens; D009943:Organophosphorus Compounds; D009946:Organothiophosphorus Compounds; D016685:Mitomycin; C026086:methyl demeton