[Cancer chemotherapy in the field of surgery--with special reference to stomach cancer].
The history of adjuvant chemotherapy for gastric cancer in Japan was overviewed. As the most important trials of the early days, the trials of Imanaga Group (Cooperative Study Group supported by the grants from the Ministry of Health and Welfare) and of National Cancer Center Hospital were presented with final results. Furthermore, as the recent trials, the results of Cooperative Study Group of Surgical Adjuvant Chemotherapy for Gastric Cancer in Japan (organized by Prof. K. Inokuchi) and of our study at Hiroshima University Hospital were presented. More than ten years has passed since the above early trials took place and the increase of five-year survival rate was clearly demonstrated in comparing the results obtained earlier days and current ones especially in stage III cases. This increase is attributed to the advances of cancer chemotherapy in the province of surgery.
D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D004359:Drug Therapy, Combination; D006801:Humans; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D013488:Suppositories; D013607:Tablets; D005641:Tegafur / Q000008:administration & dosage
D000903:Antibiotics, Antineoplastic; D008937:Mitomycins; D013488:Suppositories; D013607:Tablets; D005641:Tegafur; D016685:Mitomycin; D004317:Doxorubicin; C027260:pirarubicin