[Ascending and descending projections of posterior hypothalamus neurons immunoreactive to serotonin after administration of 5-hydroxytryptophan in cats].
Through combined retrograde labeling with HRP and serotonin immunohistochemistry, we have demonstrated that ventral and caudal hypothalamic neurons, both non-immunoreactive and immunoreactive to serotonin after administration of 5-hydroxytryptophane, give rise to direct ascending projections to the entire cerebral cortex as well as direct descending projections to the nucleus locus coeruleus alpha in the pontine tegmentum. A retrograde double labeling method with fluorescent dyes further suggested that the population of ascending hypothalamic neurons is different from that of descending ones.
D006916:5-Hydroxytryptophan / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D002415:Cats; D002540:Cerebral Cortex / Q000032:analysis; D007031:Hypothalamus / Q000032:analysis*; D007034:Hypothalamus, Posterior / Q000032:analysis* / Q000033:anatomy & histology; D007118:Immunoassay; D008125:Locus Coeruleus / Q000032:analysis; D009434:Neural Pathways / Q000032:analysis / Q000033:anatomy & histology; D009474:Neurons / Q000032:analysis*; D012701:Serotonin / Q000032:analysis*
D012701:Serotonin; D006916:5-Hydroxytryptophan
Projections ascendantes et descendantes des neurones de l'hypothalamus posterieur immunoréactifs à la sérotonine aprés administration de 5-hydroxytryptophane chez le chat.