[Study of the physico-chemical properties of prostaglandin F2 alpha and its complexes].
To study the intracellular action mechanisms of prostaglandin F2 alpha its interaction with lipid components of biological membranes was investigated. It has been found that prostaglandin forms a complex with phosphatidylcholine and cholesterol. Immobilization ability of phospholipids is changed in the course of complex formation. Ability of prostaglandin F2 alpha for complex formation with insulin was also observed. Combination of monolayer technique and electron microscopy made possible to discover molecular reconstructions when prostaglandin is incorporated into monolayer of biologically active compounds.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002784:Cholesterol; D015237:Dinoprost; D007328:Insulin; D046911:Macromolecular Substances; D008854:Microscopy, Electron; D008968:Molecular Conformation; D010713:Phosphatidylcholines; D011460:Prostaglandins F
D007328:Insulin; D046911:Macromolecular Substances; D010713:Phosphatidylcholines; D011460:Prostaglandins F; D002784:Cholesterol; D015237:Dinoprost
Izuchenie fiziko-khimicheskikh svoĭstv prostaglandinaF2 alpha i ego kompleksov.