Identification of penicillin-binding protein 5a of Bacillus megaterium KM as a DD-carboxypeptidase.
Measurement of the stabilities of DD-carboxypeptidase activity and the penicillin-binding activity of proteins 5 and 5a in membranes isolated from vegetative cells and stage-V forespores suggests that the unique sporulation-specific protein 5a may be a penicillin-sensitive DD-carboxypeptidase.
D001410:Bacillus megaterium / Q000187:drug effects / Q000201:enzymology*; D001426:Bacterial Proteins; D002268:Carboxypeptidases / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D002729:Chloromercuribenzoates / Q000494:pharmacology; D006602:Hexosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase / Q000378:metabolism*; D046915:Penicillin-Binding Proteins; D010458:Peptidyl Transferases; D020245:p-Chloromercuribenzoic Acid
D001426:Bacterial Proteins; D002352:Carrier Proteins; D002729:Chloromercuribenzoates; D046915:Penicillin-Binding Proteins; D020245:p-Chloromercuribenzoic Acid; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D002268:Carboxypeptidases; D002267:Muramoylpentapeptide Carboxypeptidase