Efficacy of oral and transepidermal application of diethylcarbamazine citrate in Brugia malayi infected cats.
This experimental study showed that daily oral administration of DEC at levels of 5 to 15 mg/kg/day with food for 3 weeks decreased the level of both developing and adult B. malayi in infected cats. There were no adverse reactions due to the medication. Topical application of 5% DEC in skin cream or in mineral oil appears to be effective in killing developing B. malayi in cats.
D000284:Administration, Oral; D000287:Administration, Topical; D000818:Animals; D002009:Brugia; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D004049:Diethylcarbamazine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D005368:Filariasis / Q000188:drug therapy / Q000662:veterinary*; D006801:Humans
D004049:Diethylcarbamazine