Local intraarterial thrombolysis in vertebrobasilar thromboembolic disease.
The poor prognosis of basilar artery occlusion is well known. Systemic anticoagulation rarely prevents a lethal outcome. A new therapeutic approach involves selective perfusion of streptokinase through the vertebrobasilar artery via a coaxial catheter system. Three of five reported cases demonstrated successful vascular recanalization with clinical improvement.
D000328:Adult; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D002542:Intracranial Embolism and Thrombosis / Q000188:drug therapy*; D008875:Middle Aged; D013300:Streptokinase / Q000008:administration & dosage*; D014711:Vertebral Artery; D014715:Vertebrobasilar Insufficiency / Q000188:drug therapy*
D013300:Streptokinase