A clinical comparison between commercially available mucin- and CMC-containing saliva substitutes.
In this investigation, the subjective impressions of patients, suffering from severe xerostomia, have been recorded after symptomatic treatment with different CMC- and mucin-containing artificial saliva over 3 years. A total number of 137 patients divided into 3 groups participated. Group I (40 patients) used CMC-containing artificial saliva, group II (61 patients) alternately used CMC- and mucin-containing artificial saliva and group III (36 patients) used mucin-containing artificial saliva. From this study it is concluded that artificial saliva containing mucins proved to be of benefit to patients suffering from xerostomia.
D000328:Adult; D000368:Aged; D002266:Carboxymethylcellulose Sodium / Q000008:administration & dosage*; D003258:Consumer Behavior; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008747:Methylcellulose / Q000031:analogs & derivatives*; D008875:Middle Aged; D009067:Mouthwashes / Q000008:administration & dosage*; D009077:Mucins / Q000008:administration & dosage*; D012464:Saliva, Artificial / Q000008:administration & dosage*; D014987:Xerostomia / Q000628:therapy*
D009067:Mouthwashes; D009077:Mucins; D012464:Saliva, Artificial; D008747:Methylcellulose; D002266:Carboxymethylcellulose Sodium