Ivermectin for the control of swine scabies: relative values of prefarrowing treatment of sows and weaning treatment of pigs.
Ivermectin given in a single subcutaneous dose (300 micrograms/kg of body weight) was tested for activity against swine scabies (Sarcoptes scabiei). Efficacy was determined by recoveries of mites from ear scrapings and by observations of clinical signs. Treatment of infected sows 8 to 37 days before farrowing eliminated scabies from the sows and prevented its transmission to their offspring. Pigs farrowed by ivermectin-treated sows remained noninfected throughout the study regardless of whether they were treated with ivermectin at weaning. Placebo-treated sows remained infected and transmitted scabies to their offspring. Ivermectin treatment of pigs at weaning eliminated the infection, whereas placebo treatment did not. The placebo-treated pigs remained infected while in the nursery, but ivermectin treatment eliminated the infection when they were moved to the growing and finishing floor at 12 weeks of age. It appears that an effective control program for swine scabies using ivermectin could be based on a single treatment of the sows before farrowing. Any infection (epizootic) appearing in growing pigs could be controlled by a single treatment of all in-contact pigs.
D000818:Animals; D005260:Female; D007306:Insecticides / Q000627:therapeutic use*; D007559:Ivermectin; D007783:Lactones / Q000627:therapeutic use*; D011247:Pregnancy; D011270:Pregnancy, Animal; D012520:Sarcoptes scabiei; D012532:Scabies / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D012867:Skin / Q000469:parasitology; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology / Q000517:prevention & control*; D014886:Weaning
D007306:Insecticides; D007783:Lactones; D007559:Ivermectin