Immunocytochemical demonstration of a novel peptidergic neurone system in the cat brain with an anti-growth hormone-releasing factor serum.
In 15-day-, 1-month- and 1.5-month- old cats an antiserum against hpGRF-44 stained a novel hypothalamo-infundibular neuroglandular system. Its intra-eminential processes present an important development between 15 and 30 days of age. Perikarya and nerve fibres, which are abundant in several brain areas as early as the 15th day, suggest that the peptide revealed by hpGRF-44 antibodies also acts as a neuromodulator.
D000818:Animals; D001921:Brain / Q000166:cytology*; D002415:Cats / Q000033:anatomy & histology*; D005260:Female; D005455:Fluorescent Antibody Technique; D013007:Growth Hormone-Releasing Hormone / Q000276:immunology*; D006651:Histocytochemistry; D007106:Immune Sera / Q000276:immunology*; D008297:Male; D010455:Peptides / Q000502:physiology*
D007106:Immune Sera; D010455:Peptides; D013007:Growth Hormone-Releasing Hormone