Detection of an antigen to primary biliary cirrhosis in wild type and petite mutant Saccharomyces cerevisiae.
Antigens to primary biliary cirrhosis (PBC) appeared to be identical in wild type (rho+) and petite (rho o) mutant S.cerevisiae. As the latter mutants lack functional mitochondria, the PBC antigens, which are associated with mitochondrial ATPase in other cells, may be of nucleocytoplasmic origin.
D000941:Antigens / Q000302:isolation & purification*; D008105:Liver Cirrhosis, Biliary / Q000276:immunology*; D008929:Mitochondria, Heart / Q000276:immunology; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000276:immunology*
D000941:Antigens