Allotype polymorphism of serum globulins (Gp system) in pigs.
By alloimmunization with whole serum reagents were obtained which revealed two new allotypes, G8 and P30, in pigs. Evidence is presented that the allotypes G8, P30 and previously described G4 and G6 are controlled by three complex autosomal allelic genes forming a closed system. For this new allotype system we propose the designation Gp (globulin, pig). For alternative G4-G8 and G6-P30, forming pairs of mutually exclusive alloantigens, it is proposed to use a standard designation GpA-Gpa and GpB-Gpb respectively.
D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005838:Genotype; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D008297:Male; D010641:Phenotype; D011110:Polymorphism, Genetic; D012712:Serum Globulins / Q000235:genetics*; D013045:Species Specificity; D013552:Swine / Q000276:immunology*
D007126:Immunoglobulin Allotypes; D012712:Serum Globulins