Effect of DDAVP on plasma level of factor XII.
The effect of DDAVP on blood coagulation factors was investigated after its intravenous infusion into normal subjects. A marked increase in factor XII was observed in addition to the expected rise of factor VIII coagulant activity (VIII:C), factor VIII related antigen (VIIIR:Ag) and plasminogen activator, DDAVP also produced a concomitant but less pronounced rise of factor VII, but there was no change in factors V, IX, X and XI.
D000328:Adult; D000941:Antigens / Q000032:analysis; D001127:Arginine Vasopressin / Q000494:pharmacology*; D001779:Blood Coagulation Factors / Q000032:analysis; D003894:Deamino Arginine Vasopressin / Q000494:pharmacology*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005174:Factor XII / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D010960:Plasminogen Activators / Q000097:blood; D013997:Time Factors; D014841:von Willebrand Factor
D000941:Antigens; D001779:Blood Coagulation Factors; D014841:von Willebrand Factor; D001127:Arginine Vasopressin; D005169:Factor VIII; D005174:Factor XII; D010960:Plasminogen Activators; D003894:Deamino Arginine Vasopressin