Localization of the antigen and antibodies in the placenta of immunized sheep.
Placentomata of sheep immunized with human serum albumin (HSA) were examined. Both HSA and immunoglobulins were found in the maternal part and maternofetal border of the placenta using FITC labelled antisera on paraffin sections. Radiolabelled HSA was also detected in the fetal blood. The ultrastructure of placentomata revealed immunopathological process.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D008854:Microscopy, Electron; D010920:Placenta / Q000276:immunology* / Q000648:ultrastructure; D011247:Pregnancy; D012709:Serum Albumin / Q000276:immunology; D012756:Sheep
D000936:Antigen-Antibody Complex; D012709:Serum Albumin