A grading system for bone marrow cytogenetics and its use as a standard for quality control.
A grading system has been developed to assess the quality of the results of bone marrow cytogenetic procedures. The results of 3 1/2 years use of this grading system are reported. This grading system is a satisfactory internal standard for quality control and is adaptable for use as an external standard. The use of such an internal standard will improve the performance of the cytogenetics laboratory and will validate the quality of the results of cytogenetic examination. The use of an external standard will stimulate the standardization and improvement of cytogenetic laboratory techniques and may be used to develop performance standards for accreditation of both bone marrow and other cytogenetic laboratories. Internal and external quality controls have been used in general medical laboratories for many years, and their use should be instituted by cytogenetic laboratories as well.
D001853:Bone Marrow / Q000648:ultrastructure*; D003582:Cytogenetics; D004492:Edetic Acid; D006493:Heparin; D006801:Humans; D011786:Quality Control
D006493:Heparin; D004492:Edetic Acid