Early diagnosis of Q fever: detection of immunoglobulin M by radioimmunoassay and enzyme immunoassay.
The use of a radioimmunoassay and an enzyme immunoassay for early diagnosis of Q fever is described, both of which are based on the IgM antibody-capture principle. A commercially available phase II antigen and a labeled, purified anti-Q-IgG of human origin were employed. With these tests Q fever antibodies were detected earlier in the course of infection than with the complement fixation test.
D000907:Antibodies, Bacterial / Q000032:analysis*; D003168:Complement Fixation Tests; D003381:Coxiella / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000032:analysis*; D011778:Q Fever / Q000175:diagnosis* / Q000276:immunology; D011863:Radioimmunoassay
D000907:Antibodies, Bacterial; D007075:Immunoglobulin M