Relationships among the TRH, REM latency, and dexamethasone suppression tests: preliminary findings.
The DST and TRH stimulation test (TRHST) were administered to 68 depressed in- and outpatients; 28 subjects also received 2 nights of sleep EEG. Results indicated that (1) the TRHST differentiated RDC endogenous from nonendogenous unipolar subtypes at the 5 but not the 7 IuU/ml threshold, (2) neither order nor timing of DST and TRHST testing affected TRHST response, (3) the TRHST detected subjects not identified by the DST, and (4) REM latency detected some patients (23%) not identified by either the TRHST or DST.
D000553:Ambulatory Care; D001714:Bipolar Disorder / Q000175:diagnosis; D003866:Depressive Disorder / Q000175:diagnosis*; D003907:Dexamethasone; D004569:Electroencephalography; D005260:Female; D006760:Hospitalization; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012895:Sleep, REM; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D013973:Thyrotropin-Releasing Hormone; D003907:Dexamethasone; D013972:Thyrotropin; D006854:Hydrocortisone