Ultrastructural analysis of the ribonucleoprotein structure of nascent hnRNA.
Active transcription units are visualized in the electron microscope and the ribonucleoprotein structure of nascent transcripts is analyzed by the technique of RNP fibril mapping. This ultrastructural approach has demonstrated that the nonrandom RNP structure observed is correlated with, and perhaps mediates, a specific RNA processing event.
D000260:Adenoviruses, Human / Q000235:genetics; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D004175:Diptera / Q000648:ultrastructure; D004331:Drosophila melanogaster / Q000648:ultrastructure; D006367:HeLa Cells; D006801:Humans; D008854:Microscopy, Electron; D009694:Nucleic Acid Precursors / Q000378:metabolism; D009698:Nucleoproteins / Q000378:metabolism; D012332:RNA, Heterogeneous Nuclear / Q000096:biosynthesis; D012261:Ribonucleoproteins / Q000378:metabolism; D014158:Transcription, Genetic
D009694:Nucleic Acid Precursors; D009698:Nucleoproteins; D012332:RNA, Heterogeneous Nuclear; D012261:Ribonucleoproteins