The Rh antigen Tar (Rh40) causing haemolytic disease of the newborn.
Haemolytic disease of the newborn (HDN), in the fifth child of an Israeli of Moroccan origin, disclosed anti-Tar in the serum of the mother. This anti-Tar, the second reported example, is the first to cause HDN and was stimulated by previous pregnancies. Tests on blood from the family show that the Tar antigen in this family is associated with a CDe complex which gives rise to a weak expression of the D antigen. A study of 1327 donors in Jerusalem revealed one Tar + propositus.
D003298:Coombs Test; D004899:Erythroblastosis, Fetal / Q000235:genetics* / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000276:immunology*; D007557:Israel; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System
D007519:Isoantigens; D012204:Rh-Hr Blood-Group System