Quantification of gray/white matter in neonates and adults.
Quantitation of gray/white matter is important in evaluation of cerebral blood flow, atrophy, and development of the brain. First-order statistical analysis of neonatal computed tomographic (CT) images revealed that there was only a 6 Hounsfield unit (H) difference between gray and white matter compared with the observed 3 H for the standard deviation over the field of a skull water phantom. Scene segmentation methods based on first-order statistics proved unsuccessful in separating gray and white matter. A new regional clustering algorithm based on local textural properties was developed for separation of these structures.
D000328:Adult; D000375:Aging; D001921:Brain / Q000033:anatomy & histology*; D006801:Humans; D007231:Infant, Newborn; D008953:Models, Anatomic; D009413:Nerve Fibers, Myelinated; D014057:Tomography, X-Ray Computed / Q000379:methods*