A symptomatic and cystometric comparison of terodiline with emepronium in the treatment of women with frequency, urgency and incontinence.
Terodiline has been compared with emepronium in the treatment of 20 women suffering with frequency, urgency and incontinence in a double-blind, two-way cross-over study with fixed placebo as wash-out. A significant number of patients preferred terodiline treatment and a closer correlation between symptomatic and cystometric improvement has been seen during treatment with this drug. Regression analyses indicate that patients with high micturition frequencies (12 to 15 per 24 hours) benefit more from treatment than those with lower frequencies do.
D000328:Adult; D000368:Aged; D002082:Butylamines / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004629:Emepronium / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*; D012044:Regression Analysis; D001743:Urinary Bladder / Q000503:physiopathology*; D014549:Urinary Incontinence / Q000188:drug therapy* / Q000503:physiopathology; D014554:Urination / Q000187:drug effects
D002082:Butylamines; D002121:Calcium Channel Blockers; D000644:Quaternary Ammonium Compounds; D004629:Emepronium; C010637:terodiline