Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells. An evaluation of methodology for detection of SCEs and of persistent DNA lesions towards the frequencies of observed SCEs.
D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D003434:Crossing Over, Genetic / Q000187:drug effects*; D005260:Female; D008722:Methods; D008741:Methyl Methanesulfonate / Q000494:pharmacology*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D008937:Mitomycins; D016685:Mitomycin; D008741:Methyl Methanesulfonate