Enhancement of antibody response in Japanese quails by acute NO2 exposure.
The effect of acute exposure to nitrogen dioxide (NO2) on anti-SRBC antibody response in two lines of Japanese quails, high and low responder, was investigated. Mean survival time of 11- to 13-week-old quails after exposure to 20 ppm NO2 was 12.0 hr. The high responder line lived longer than the low responder line. Changes of spleen weights of both lines were not observed in 10- and 20-ppm NO2 exposure for 4 hr. Anti-SRBC antibody response in high responder quail was significantly enhanced by 20-ppm NO2 exposure for 4 hr and the response in low responder quail was slightly enhanced. A similar, although somewhat less pronounced, tendency was observed also after 10-ppm NO2 exposure. These results suggest that acute NO2 exposure enhances the antibody response of Japanese quails.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D001273:Atmosphere Exposure Chambers; D003370:Coturnix; D005260:Female; D006462:Hemolytic Plaque Technique; D008297:Male; D009585:Nitrogen Dioxide / Q000276:immunology* / Q000494:pharmacology; D009929:Organ Size / Q000187:drug effects; D012737:Sex Factors; D013154:Spleen / Q000187:drug effects
D009585:Nitrogen Dioxide