Toxicity of fungal metabolites to albino rats.
The oral intubation of culture filtrates produced nephrotoxic damages in the form of marked capillaritis, shrinkage and early fibrosis of glomeruli. Hypertrophy and degeneration of tubular epithelium were also evident. The spleen of treated animals revealed subacute splenitis in the form of congestion of the splenic sinuses.
D000818:Animals; D001230:Aspergillus; D001231:Aspergillus flavus; D007674:Kidney Diseases / Q000139:chemically induced; D007684:Kidney Tubules / Q000473:pathology; D009183:Mycotoxins / Q000633:toxicity*; D051381:Rats; D013154:Spleen / Q000473:pathology
D009183:Mycotoxins