[Clinical effectiveness and administration of streptodecase in patients with acute myocardial infarction].
The authors analyze the efficacy of the treatment with combined streptodecase and heparin of patients with acute myocardial infarction as compared with the control receiving symptomatic therapy. The treatment contributed to rapid removal of pains, accelerated positive dynamics of the ECG, the recovery of the normal heart rhythm and conduction, and compensation for the symptoms of circulatory failure. In addition, the patients manifested less rarely the dissemination of the necrotic zone, the development of recurrent infarction, thromboembolism, heart aneurysm and rupture. Of great importance was the absence of hemorrhagic and allergic reactions, specific for therapy with native thromboembolic drugs. One-stage intravenous injection of all the therapeutic dose of streptodecase considerably simplifies the performance of thrombolytic therapy.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000627:therapeutic use*
D006493:Heparin; D013300:Streptokinase
Klinicheskaia éffektivnost' i metodika primeneniia streptodekazy u bol'nykh ostrym infarktom miokarda.