[Experimental study of the gastric digestion of milk proteins and the lysosomal proteinases in young animals].
The content of proteinases (proenzymes of pepsin and rennin) in the stomach of newborn rats was found to be significant. However, the proteolytic activity in the gastric contents during milk feeding proper (the first 12 days of life) was fairly low. The activity of marker lysosomal enzymes (acid phosphatase and cathepsins) in lysosomal fraction isolated from the gastric mucosa of the newborn animals was 2 times higher than that seen towards the end of milk feeding. It is suggested that lysosomal proteinases of the stomach, absorbed according to the type of milk protein pinocytosis, are involved into intracellular digestion.
D000135:Acid Phosphatase / Q000378:metabolism*; D000367:Age Factors; D000818:Animals; D002403:Cathepsins / Q000378:metabolism; D012085:Chymosin / Q000378:metabolism; D004063:Digestion; D010450:Endopeptidases / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D008247:Lysosomes / Q000201:enzymology*; D008894:Milk Proteins / Q000378:metabolism*; D010434:Pepsin A / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D008894:Milk Proteins; D000135:Acid Phosphatase; D002403:Cathepsins; D010450:Endopeptidases; D010434:Pepsin A; D012085:Chymosin
Perevarivanie belkov moloka v zheludke i lizosomal'nye proteinazy v rannem vozraste v éksperimente.