Endotoxaemia in cystic fibrosis: response to antibiotics.
In a study of 6 children with cystic fibrosis receiving intravenous antibiotics for pseudomonas lung infection, serum endotoxin values were monitored by a modification of the limulus lysate technique. The values fell with treatment, reflecting a response that was not always apparent on clinical assessment. Endotoxin concentrations may offer a more precise way of monitoring the effects of antibiotic treatment in CF patients.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002228:Carbenicillin / Q000627:therapeutic use; D002648:Child; D003550:Cystic Fibrosis / Q000097:blood / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004731:Endotoxins / Q000097:blood*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011550:Pseudomonas aeruginosa
D000900:Anti-Bacterial Agents; D004731:Endotoxins; D005839:Gentamicins; D002228:Carbenicillin