[Clinical characteristics and hormonal-metabolic homeostasis in patients with insulin-dependent diabetes mellitus with stable and labile courses].
Combined examination of 117 patients with insulin-dependent diabetes mellitus revealed the clinical and hormonal features of stable and labile diseases. Emphasis is laid on the complexity of the lability phenomenon; evidence is given for the necessity of differentiating between genuine lability and that of the iatrogenic type. The importance of hormonal shifts (depletion of the secretory capability of the insulin-producing apparatus and reduction of contrainsular effects) for the origin of destabilization of glucose homeostasis is discussed.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D002096:C-Peptide / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D003925:Diabetic Angiopathies / Q000097:blood; D005260:Female; D005951:Glucose Tolerance Test; D006706:Homeostasis; D006801:Humans; D007328:Insulin; D007330:Insulin Antibodies / Q000032:analysis; D008297:Male; D008875:Middle Aged; D013963:Thyroid Hormones / Q000097:blood; D013997:Time Factors
D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin; D007330:Insulin Antibodies; D013963:Thyroid Hormones
Osobennosti kliniki i gormonal'no-obmennogo gomeostaza u bol'nykh insulinozavisimym sakharnym diabetom pri ego stabil'nom i labil'nom techenii.