Genetic analysis of B2t, the structural gene for a testis-specific beta-tubulin subunit in Drosophila melanogaster.
Genetic analysis of the B2t locus has resulted in the recovery of four recessive mutations in the B2t structural gene and a deficiency that deletes the locus. Two of the mutations were recovered as suppressors of B2tD, a dominant male sterile mutation at the locus, and two were induced on wild-type chromosomes. All four mutant genes encode beta 2-tubulin subunits that are synthesized at normal rates but do not accumulate. All mutants are completely male sterile as homozygotes.
D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics; D005796:Genes; D005808:Genes, Recessive; D008297:Male; D009154:Mutation; D013737:Testis / Q000378:metabolism*; D014404:Tubulin / Q000235:genetics*
D014404:Tubulin