The use of monoclonal antibody 791T/36 in the immunoscintigraphy of primary and metastatic carcinoma of the breast.
Radiolabelled monoclonal antibody 791T/36 raised against a human osteogenic sarcoma cell line was used to image primary and metastatic tumours in 13 patients with mammary carcinoma. Successful imaging was achieved in 3 of 5 women with primary tumours, in one woman with hepatic metastases, 3 with loco-regional metastases and one with pleural involvement. No localization was demonstrated at sites of known bone involvement in 5 patients.
D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007204:Indium; D007457:Iodine Radioisotopes; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013382:Subtraction Technique; D013667:Technetium
D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes; D011868:Radioisotopes; D007204:Indium; D013667:Technetium