[Kinetics of passive transport of Ca2+ in vesicles of myometrial sarcolemma].
It has been shown that kinetics of 45Ca2+ yield from vesicular fraction of plasmic membranes of myometrium cells into the medium with 1 mM EGTA complies with the regularities of irreversible reaction of the third order. It is concluded that Ca2+  yield from the vesicules is not reduced to a simple diffusion transmembrane movement of ions, it underlies the interaction between three calcium ions and sarcolemma in the transfer loci. Values of rate constant and initial rate of Ca2+ yield, of the period of half-yield for specimens obtained from the myometrium of pregnant and non-pregnant rabbits were determined. By comparing the values of passive and ATP-dependent transmembrane currents of calcium ions there is analysed the role of the sarcolemma as Ca2+-transporting structure providing for the processes of myometrium contraction and relaxation.
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D004533:Egtazic Acid / Q000494:pharmacology; D005260:Female; D007700:Kinetics; D009215:Myometrium / Q000378:metabolism*; D011247:Pregnancy; D011817:Rabbits; D012508:Sarcolemma / Q000378:metabolism*
D004533:Egtazic Acid; D002118:Calcium
Kinetika passivnogo transporta Ca2+ v vezikulakh sarkolemmy miometriia.