[Impairment of recovery of the hematopoietic stem pool after long-term external irradiation].
A stable decrease in the polypotent CFUs pool of CBA mice was observed after long-term irradiation the cumulative doses being 10 Gy (0.06-0.5 Gy/day) and 1.8-2 Gy (0.01 and 0.5 Gy/day). With the comparable values of the cumulative dose the share of the unrepaired part of the haemopoietic pool increased with the increase in total time of exposure.
D000818:Animals; D002452:Cell Count; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000528:radiation effects*; D051379:Mice; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D013997:Time Factors; D014916:Whole-Body Irradiation
Narushenie vosstanovleniia stvolovogo krovetvornogo pula posle dlitel'nogo vneshnego oblucheniia.