[Neurophysiological and pharmacological characteristics of latent intercaudate asymmetry in the cat].
The head-turning behavior in electrical stimulation of right and left caudate nuclei was tested in chronic experiment in cats. Local head-turning in contra-or ipsilateral direction was found in stimulation of the right caudate nucleus while in the left caudate stimulation generalized locomotor reactions such as controlateral circling, were a more frequent feature. Drugs exerted different effects on reactions of the right and left caudate nuclei to electrical stimulation. L-DOPA and haloperidol increased the intercaudate asymmetry whereas apomorphin and clozapine revealed no such effect. The neurophysiological mechanisms of intercaudate asymmetry and its contribution in pathogenesis of extrapyramidal disorders, are discussed.
D000818:Animals; D014151:Anti-Anxiety Agents; D001058:Apomorphine / Q000494:pharmacology; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000494:pharmacology; D002415:Cats; D002421:Caudate Nucleus / Q000502:physiology*; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D004558:Electric Stimulation; D007839:Functional Laterality; D006220:Haloperidol / Q000494:pharmacology; D009043:Motor Activity / Q000502:physiology*; D011954:Receptors, Dopamine / Q000502:physiology*
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D011954:Receptors, Dopamine; D001569:Benzodiazepines; C015756:clazepam; D004295:Dihydroxyphenylalanine; D006220:Haloperidol; D001058:Apomorphine
Neĭrofiziologicheskaia i farmakologicheskaia kharakteristika skrytoĭ mezhkaudatnoĭ asimmetrii u koshek.