Paradoxical release of LH under TRH dynamic test in patients suffering from "psychogenic" erective sexual impotency: lack of neuroradiological signs for hypophyseal lesions.
More than two thirds of the patients suffering from "psychogenic" erective sexual impotency display a paradoxical LH response to the injection of 200 micrograms of TRH. As it is known that similar responses exist in patients with gonadotropic cell adenomas, we undertook a tomographic examination of the sella turcica in 8 such patients. In none of the patients did the results favour the existence of a microadenoma. Though the hypothesis of an infra-radiological microadenoma cannot be excluded, it is highly plausible that the origin of the paradoxical response observed is a functional impairment of the hypothalamo-hypophyso-gonadal regulation.
D000236:Adenoma / Q000000981:diagnostic imaging; D000328:Adult; D007172:Erectile Dysfunction / Q000097:blood*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging; D011859:Radiography; D012658:Sella Turcica / Q000000981:diagnostic imaging; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D013973:Thyrotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone