Plasmodium falciparum infection in Bisazir chemosterilized Anopheles dirus in laboratory studies.
Bisazir, at a 0.5% solution induced sterility in males and at a 1.5% solution in female A. dirus. These sterilizing doses reduced P. falciparum infection in mosquitoes, however, they can still transmit malaria. It is concluded that by the concentration of 1.5 and 2.0% that induced complete sterility in males and females are not safe in sterile-male release programme for the control of A. dirus, unless all females were eliminated prior to release.
D000818:Animals; D000830:Animals, Laboratory; D000852:Anopheles / Q000187:drug effects* / Q000469:parasitology / Q000502:physiology; D001388:Aziridines / Q000494:pharmacology*; D001389:Azirines / Q000494:pharmacology*; D003433:Crosses, Genetic; D005260:Female; D005298:Fertility / Q000187:drug effects; D008297:Male; D010058:Oviposition / Q000187:drug effects; D010963:Plasmodium falciparum / Q000254:growth & development*; D011679:Pupa / Q000187:drug effects
D001388:Aziridines; D001389:Azirines; C006762:bisazir