Temporal distinction between repair and mutagenesis of benzopyrene adducts after SOS induction in Escherichia coli.
Plasmid DNA covalently modified with benzopyrene diol epoxide was introduced into Escherichia coli strains which differed in their capacity for repair and mutagenesis at various times after SOS induction. The uvrA+-dependent repair activity rose and fell before umuC+SOS-dependent mutagenesis was fully expressed.
D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; D001580:Benzopyrenes / Q000633:toxicity*; D004260:DNA Repair / Q000528:radiation effects; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D007700:Kinetics; D009154:Mutation; D010957:Plasmids; D014466:Ultraviolet Rays
D001580:Benzopyrenes; D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide