Long-term stress-induced analgesia blocked by scopolamine.
An 'opioid' form of analgesia ('long-term analgesia') was completely blocked by scopolamine. This effect of a muscarinic antagonist suggests that muscarinic cholinergic processes may play an important role in this analgesia and in other types of endogenous pain control.
D000818:Animals; D004597:Electroshock; D004924:Escape Reaction / Q000187:drug effects; D008297:Male; D009115:Muridae; D009619:Nociceptors / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects; D011976:Receptors, Muscarinic / Q000187:drug effects; D012601:Scopolamine / Q000494:pharmacology*; D013312:Stress, Physiological / Q000150:complications*
D011976:Receptors, Muscarinic; D012601:Scopolamine