Pesticides and breast cancer, popcorn and colorectal cancer: innovation versus fashion in dietary epidemiology.
Organochlorine insecticides and polychlorinated biphenyls (PCBs) have been found to be carcinogenic in animal studies. Eight of these insecticides and PCBs have been detected in human milk samples. Their possible contribution to breast cancer has never been seriously studied. Substances which cause scarring or provide anchorage when embedded in tissue can contribute to carcinogenesis. Sharp outer fragments of popcorn kernels may contribute to the type of tissue fibrosis associated with colorectal cancer. Lack of innovation in dietary cancer epidemiology is discussed.
D001943:Breast Neoplasms / Q000139:chemically induced*; D003110:Colonic Neoplasms / Q000209:etiology*; D005260:Female; D006801:Humans; D007306:Insecticides / Q000009:adverse effects*; D011078:Polychlorinated Biphenyls / Q000009:adverse effects*; D012004:Rectal Neoplasms / Q000209:etiology*; D003313:Zea mays / Q000009:adverse effects*
D007306:Insecticides; D011078:Polychlorinated Biphenyls