Anti-hypertensive therapy in the elderly and its effects on cerebral function.
Seventeen patients ranging in age from 67 to 86 years were entered into a double-blind, crossover study of Moducren and placebo. Psychometric testing using the Clifton Assessment Procedure for the Elderly was performed at the start of the study and at the end of each 4-week test period. The total length of the study was 18 weeks. Apart from effectively reducing blood pressure in elderly hypertensives without causing a high incidence of side effects, plasma potassium, blood urea and cerebral function were all unaffected by Moducren.
D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects* / Q000502:physiology; D002986:Clinical Trials as Topic; D003071:Cognition / Q000187:drug effects*; D004311:Double-Blind Method; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008875:Middle Aged
D000959:Antihypertensive Agents