Transfer of immunity against Pseudomonas aeruginosa P11-1 in Galleria mellonella larvae.
Larvae of Galleria mellonella may be immunized against Pseudomonas aeruginosa by the transfer of whole hemolymph, cell-free hemolymph or hemocytes from insects previously immunized with the lipopolysaccharide of the homologous organisms. Whole immune hemolymph injected as early as 3 hours after vaccination confers protection which persists as long as 40 hours. Hemocytes alone confer good protection when transferred as early as 30 minutes after, and up to about 4 hours after immunization. Transferred protection does not appear to be due to excess immunogen in the hemolymph.
D000818:Animals; D001428:Bacterial Vaccines; D006458:Hemolymph / Q000276:immunology; D007109:Immunity; D007111:Immunity, Cellular; D007116:Immunization, Passive; D007814:Larva / Q000276:immunology; D007915:Lepidoptera / Q000276:immunology*; D009036:Moths / Q000276:immunology*; D011550:Pseudomonas aeruginosa / Q000276:immunology
D001428:Bacterial Vaccines