[Development of human fetal skin from the beginning of pregnancy to the 6th month. Light microscopy study].
The human foetal skin has been studied in 15 foetuses from the 8th to the 24th week of pregnancy, to analyse the most significative stages of its evolution. The skin of the ventral and dorsal regions of the hand and fingers has been studied. Just after excision, the hand buds have been fixed with neutral formaline, dehydrated, clarified and embedded in paraffin. The microtomic sections have been stained using different histological techniques. Different characteristics between the skin that will differentiate into thin and thick aspects have been observed already from the earliest stages of evolution. The differences occur especially at the level of the subepithelial mesenchyme, that conditions the development and the evolution of the two kinds of skin.
D002454:Cell Differentiation; D005333:Fetus / Q000166:cytology*; D005865:Gestational Age; D006652:Histological Techniques; D006801:Humans; D012867:Skin / Q000196:embryology*
L'évolution de la peau humaine foetale dès le début de la grossesse jusqu'au 6e mois. Etude au microscope photonique.