Ampicillin induced septum formation in Bacillus cereus.
Cells of Bacillus cereus grown in the presence of subinhibitory concentrations of ampicillin at either 30 degrees or 45 degrees C exhibited an increase in the numbers of centres of septum formation per unit cell length. Under identical conditions of cultivation, cells of Escherichia coli grew as aseptate filaments. In general, untreated B. cereus cells grown at 45 degrees C were longer than those grown at 30 degrees C. The strain of E. coli used was unaffected in terms of filamentation by elevated growth temperature. Results are discussed in terms of the presence and availability of penicillin binding proteins and autolysins involved in cell growth, division and separation.
D000667:Ampicillin / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects* / Q000648:ultrastructure; D002455:Cell Division / Q000187:drug effects; D002473:Cell Wall / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects / Q000648:ultrastructure; D008854:Microscopy, Electron
D000667:Ampicillin