Bacterial interference in streptococcal tonsillitis.
On the basis of the presented results and those published by other investigators it can be stated that in the throat (i) bacterial interference is a multifaceted phenomenon; (ii) bacterial interference not only varies individually but also fluctuates in the individual by time and the epidemiological situation; (iii) bacterial interference among the microbes in the normal flora apparently helps the individual to combat the invading microorganisms; (iv) bacteriocins, if present, in the invading bacteria represent an important virulence factor; (v) bacterial interference as a factor of the host resistance to infection can be influenced negatively by antibiotic therapy; (vi) bacterial interference can act synergistically with antibiotics given in optimal doses saving the normal flora.
D000818:Animals; D001430:Bacteriocins / Q000502:physiology; D002648:Child; D006801:Humans; D014066:Palatine Tonsil / Q000382:microbiology; D010403:Penicillin Resistance / Q000187:drug effects; D010404:Penicillin V / Q000494:pharmacology; D010614:Pharynx / Q000382:microbiology; D011817:Rabbits; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects / Q000254:growth & development*; D014069:Tonsillitis / Q000382:microbiology*
D001430:Bacteriocins; D010404:Penicillin V