Plasma testosterone response to hCG stimulation in the male marmoset monkey (Callithrix jacchus jacchus).
In adult animals the intramuscular injection of hCG was followed by a rapid rise in plasma testosterone levels within 2-3 h and at doses of 40 and 80 i.u. hCG this primary response was followed by a second peak of testosterone at 48 h. Prepubertal marmosets also responded to hCG stimulation with a rapid increase in plasma testosterone levels within 3 h, but the magnitude of this peak was lower than that observed in adult animals and no biphasic pattern was observed. In adult and prepubertal animals a second dose of hCG (40 i.u.) administered 24 h after the initial injection failed to produce a further rapid increment in plasma testosterone levels.
D000375:Aging; D000818:Animals; D002144:Callithrix / Q000502:physiology*; D002143:Callitrichinae / Q000502:physiology*; D006063:Chorionic Gonadotropin / Q000097:blood / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008297:Male; D013737:Testis / Q000187:drug effects; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D006063:Chorionic Gonadotropin; D013739:Testosterone