Treatment of non-invasive amoebiasis--a comparison between tinidazole and metronidazole.
In a small pilot study the parasite cure rate (PCR) of non-invasive amoebiasis was compared after treatment with metronidazole 800 mg three times daily or tinidazole 600 mg twice daily for five days. Both treatment regimens were found to be highly unfavourable with PCRs of 44 and nil respectively, in contrast to previous published results showing PCR over 80%.
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D004404:Dysentery, Amebic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D009593:Nitroimidazoles / Q000627:therapeutic use*; D011897:Random Allocation; D014011:Tinidazole / Q000627:therapeutic use*
D009593:Nitroimidazoles; D014011:Tinidazole; D008795:Metronidazole