The cellular mechanisms of cardiac antiarrhythmic drug action.
In the preceding pages we have considered a number of mechanisms whereby drugs may modify arrhythmias and we also have demonstrated that certain types of action are specific to individual drugs. In addition, through the description of the use-dependence of drug effects, we have shown that the specificity of a drug's action often is attributable to its interactions with specific channels. As we learn more about the specificity of individual drug effects we should be better able not only to understand the actions of presently available drugs, but also to discover compounds that promise to be of use in the future.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D006329:Heart Conduction System / Q000187:drug effects*; D006801:Humans; D008564:Membrane Potentials / Q000187:drug effects; D008955:Models, Cardiovascular
D000889:Anti-Arrhythmia Agents