Pancreatitis and intravenous fat: an association in patients with inflammatory bowel disease.
Since recently adding Intralipid (IL) to our standard total parenteral nutrition (TPN) regimen for children with inflammatory bowel (IBD) disease, two children undergoing major intestinal resections have developed acute pancreatitis in the early postoperative period. Herein, we present the clinical summaries of these two patients, discuss the multifactoral etiologies of acute pancreatitis, and review the role of emulsified fat solutions in TPN in children with IBD.
D000208:Acute Disease; D000293:Adolescent; D002648:Child; D003092:Colitis / Q000150:complications* / Q000178:diet therapy; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects*; D005228:Fatty Acids, Essential / Q000172:deficiency; D005260:Female; D006801:Humans; D007249:Inflammation; D007410:Intestinal Diseases / Q000150:complications* / Q000178:diet therapy; D008297:Male; D010195:Pancreatitis / Q000209:etiology*; D010289:Parenteral Nutrition, Total / Q000009:adverse effects
D005217:Fat Emulsions, Intravenous; D005228:Fatty Acids, Essential