[Subcellular localization of calcium in the neurosecretory axon terminals of the neurohypophysis of the rat following stimulation by administration of hypertonic salt solution].
The calcium accumulating capacity of neurohypophysial axon terminals stimulated by the intravenous injection of hypertonic saline has been studied by using light and electron microscopic histochemical methods and X-ray microanalysis. In the stimulated neurosecretory terminals Ca++ containing granules appeared in the mitochondria. Smaller granules of similar morphological appearance occurred in the smooth endoplasmic reticulum as well. It is suggested that the mitochondria and the smooth endoplasmic reticulum are intimately involved in the regulation of the intraaxonal free calcium level during the process of vasopressin secretion.
D000818:Animals; D001369:Axons / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D002118:Calcium / Q000378:metabolism*; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000187:drug effects / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000187:drug effects / Q000378:metabolism*; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D012462:Saline Solution, Hypertonic / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013052:Spectrometry, X-Ray Emission
D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D002118:Calcium
Subcelluläre Lokalisation des Calciums in den neurosekretorischen Axonterminalen der Neurohypophyse der Ratte nach Erregung durch die Verabreichung von hypertonischer Kochsalzlösung.