[Thrombosis of a valve prosthesis: fatal cerebral embolism during thrombolytic treatment].
The authors report the first case of lethal cerebral embolism complicating thrombolytic therapy administered for thrombosis of a mitral valve prosthesis. The incidence of systemic embolism during this form of therapy appears to be at least one in five cases. It may be underestimated and should lead to further discussion as to the indications of thrombolytic therapy and surgery for thrombosis of a left heart valve prosthesis.
D000328:Adult; D002544:Cerebral Infarction / Q000473:pathology; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000139:chemically induced*; D008943:Mitral Valve / Q000601:surgery; D013927:Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014568:Urokinase-Type Plasminogen Activator / Q000009:adverse effects* / Q000627:therapeutic use
D014568:Urokinase-Type Plasminogen Activator
Thrombose de prothèse valvulaire: embolie cérébrale mortelle lors du traitement thrombolytique.