Relationship between pathogenicity in footpad lesion test and invasiveness in Escherichia coli.
Using a previously described virulence test, we established a correlation between Escherichia coli invasiveness and its ability to cause lesions in mouse footpads. The footpad lesion test thus represents a simple-to-use tool for screening pathogenic and invasive strains of E. coli.
D000818:Animals; D004487:Edema; D004926:Escherichia coli / Q000254:growth & development / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000473:pathology; D005260:Female; D005528:Foot / Q000382:microbiology / Q000473:pathology; D007668:Kidney / Q000382:microbiology; D008099:Liver / Q000382:microbiology; D051379:Mice; D009336:Necrosis; D013154:Spleen / Q000382:microbiology; D014774:Virulence