High potassium concentration in a parenteral preparation of glyceryl trinitrate. Need for caution if given by intracoronary injection.
Glyceryl trinitrate (Tridil) was given by intracoronary injection to a patient who developed coronary artery spasm during angioplasty. Transient exacerbation of chest pain and electrocardiographic changes occurred. This formulation of the drug contains a high concentration of potassium ions and should not be given by this route.
D000787:Angina Pectoris / Q000139:chemically induced*; D003329:Coronary Vasospasm / Q000188:drug therapy*; D004340:Drug Contamination; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial / Q000009:adverse effects; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*; D011188:Potassium / Q000009:adverse effects*
D005996:Nitroglycerin; D011188:Potassium