Effect of B-G region of the MHC on skin graft survival in chickens treated by injections of whole blood.
CC (B4/B4) chickens exhibited prolonged skin graft survival when pretreated by injections of whole blood from CB.R1 (B12.r1/B12.r1) donors. The difference in survival time was statistically significant between grafts from CB.R1 donors and from CB donors, differing only at the B-G region product. Pretreatment with CB blood (B12/B12) had no effect on graft survival. The results indicate that B-G region of the MHC has an effect on histocompatibility in the chicken system used.
D000818:Animals; D001790:Blood Physiological Phenomena; D002645:Chickens; D006085:Graft Survival; D007114:Immunization; D008285:Major Histocompatibility Complex; D016038:Skin Transplantation; D014184:Transplantation, Homologous