Role of DNA replication in the repression of silent mating type loci in yeast.
A putative origin of DNA replication is associated with the DNA sequences necessary for the repression of silent mating type loci in yeast. These sequences lie about a kilobase away from the affected promoters, so the repression must act at a distance. We show here that DNA replication is required for the onset of repression.
D000818:Animals; D004261:DNA Replication; D005656:Fungal Proteins / Q000235:genetics*; D005786:Gene Expression Regulation; D000072235:Mating Factor; D010455:Peptides / Q000235:genetics*; D010675:Pheromones / Q000235:genetics; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics*
D005656:Fungal Proteins; D010455:Peptides; D010675:Pheromones; D000072235:Mating Factor