Bithorax phenocopy and pattern formation. I. Spatiotemporal characteristics of the phenocopy response.
In four different lines of Drosophila melanogaster the highest frequencies of bithorax phenocopies result from ether treatment during the precellular blastoderm stages. The spatial characteristics of the phenocopy spots are dependent on the precise timing of phenocopy induction, and are not in accord with those predicted from the model of sequential determination of whole compartments put forward by Garcia-Bellido et al. in 1976. Ether treatment for 13 successive previous generations gave rise to changes in the spatiotemporal characteristics of the phenocopy response. Our results suggest the involvement of continuous diffusion-like processes in the prepatterning event which is affected by ether.
D000367:Age Factors; D000818:Animals; D004331:Drosophila melanogaster / Q000196:embryology* / Q000235:genetics; D004986:Ether / Q000494:pharmacology; D009024:Morphogenesis / Q000187:drug effects; D010641:Phenotype; D013909:Thorax
D004986:Ether