[Total proteolytic activity of the blood and its inhibitors in patients following heart operations].
The examination of 40 patients operated upon for rheumatic and congenital heart diseases has shown general proteolytic activity to be increased in patients with a rheumatic heart disease. The antitrypsin and antichymotrypsin activity were increased both in rheumatic and in congenital heart diseases. The changes were more pronounced in the development of pyo-septic and thromboembolic complications and they were found to appear earlier than clinical manifestations of the complications and can be used for prognosis of complications. To interpret the data obtained an original scheme is proposed which demonstrates a biochemical unity of the system of humoral regulation of microcirculation, inflammation and immunity.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000201:enzymology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010447:Peptide Hydrolases / Q000097:blood*; D011184:Postoperative Period; D011480:Protease Inhibitors / Q000097:blood*; D012214:Rheumatic Heart Disease / Q000201:enzymology* / Q000601:surgery; D013997:Time Factors
D011480:Protease Inhibitors; D010447:Peptide Hydrolases
Obshchaia proteoliticheskaia aktivnost' krovi i ee ingibitorov u bol'nykh posle operatsiĭ na serdtse.