[Dynamics of methemoglobin nitrite formation in whole-body gamma irradiation of rats].
Methemoglobin formation was studied in irradiated and intact rats treated with sodium nitrite (7 mg/100 g bw). During combined exposure to two factors (sodium nitrite and irradiation), the biological effect assessed according to blood methemoglobin concentration exceeded the expected value derived upon summation of separate exposures, i.e. the effect appeared to be greater than the additive one.
D000818:Animals; D005720:Gamma Rays; D008297:Male; D008706:Methemoglobin / Q000032:analysis / Q000096:biosynthesis* / Q000528:radiation effects; D010084:Oxidation-Reduction / Q000187:drug effects / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D012977:Sodium Nitrite / Q000494:pharmacology; D013053:Spectrophotometry; D013997:Time Factors; D014916:Whole-Body Irradiation
D008706:Methemoglobin; D012977:Sodium Nitrite
Dinamika nitritnogo metgemoglobinoobrazovaniia pri obshchem gamma-obluchenii krys.