Genetic studies of the lac repressor. XII. Amino acid replacements in the DNA binding domain of the Escherichia coli lac repressor.
Out of the first 62 residues of the lac repressor, 38 positions have been substituted by at least one amino acid exchange. The total number of replacements in this region is 131. Data from several studies are considered.
D000595:Amino Acid Sequence; D004269:DNA, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D009154:Mutation; D012097:Repressor Proteins / Q000235:genetics*; D013489:Suppression, Genetic; D014157:Transcription Factors / Q000235:genetics*
D004269:DNA, Bacterial; D012097:Repressor Proteins; D014157:Transcription Factors