[Thrombotic thrombocytopenic purpura (Moschkowitz's disease)--a review of the literature with a case report].
A case with thrombotic thrombocytopenic purpura (TTP) in a young female is described. The clinical picture is described as well as the pathologoanatomical finding, the characteristic and pathognomonic sins of the disease being mentioned. A survey of the literature is made, covering data about the thorough characteristic of the disease--clinical-laboratory, pathomorphological picture, etiological and pathogenetic aspects. Attention is paid to the laboratory discrepancies with the syndrome of disseminated intravascular coagulation, included in the differential diagnosis when making the clinical diagnosis of TTP. The success in the treatment of TTP during the last several years is reported with the introduction of combined therapy with corticosteroids, splenectomy, antiaggregating thrombocyte agents, exsanguination transfusion and, with the most reliable effect for the present--plasmapheresis and plasmainfusions.
D000328:Adult; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008168:Lung / Q000473:pathology; D008833:Microcirculation / Q000473:pathology; D009336:Necrosis; D009460:Neurologic Examination; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D013154:Spleen / Q000473:pathology; D013927:Thrombosis / Q000473:pathology
Trombotichna trombotsitopenichna purpura (bolest na Moshkovits)--pregled na literaturata s opisanie na edin sluchaĭ.