Carbonic anhydrase III in neuromuscular disorders.
Plasma carbonic anhydrase III (CAIII) and creatine kinase (CK) were measured in 44 patients with a variety of neuromuscular disorders. Markedly elevated CK levels were associated with similarly increased levels of CAIII. In 9 patients, only the CAIII was elevated, but in 2 patients only the CK was raised. The determination of plasma CAIII is thus an important index of muscle disorder and is probably more sensitive than CK.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002256:Carbonic Anhydrases / Q000032:analysis*; D002648:Child; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000032:analysis; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000201:enzymology*; D011863:Radioimmunoassay
D007527:Isoenzymes; D003402:Creatine Kinase; D002256:Carbonic Anhydrases