[The problem of factor VIII inhibitors in patients with congenital coagulopathies].
It is reported on a 19-year-old patient with haemophilia A, in whom after a tooth extraction haemorrhages developed which could not be commanded. Factor-VIII-inhibitors could be proved qualitatively and quantitatively. As prospective for the therapy proved to be the administration of activated prothrombin complex preparations (FEIBA). The haemorrhages stopped, the partial thromboplastin time shortened. After three weeks the patient could be dismissed from hospital treatment.
D000328:Adult; D005164:Factor IX / Q000494:pharmacology*; D015949:Factor IXa; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D006467:Hemophilia A / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D008297:Male; D006472:Oral Hemorrhage / Q000097:blood / Q000188:drug therapy; D010314:Partial Thromboplastin Time; D014081:Tooth Extraction
D005169:Factor VIII; D005164:Factor IX; D015949:Factor IXa
Zum Problem der Faktor VIII-Inhibitoren bei Patienten mit angeborenen Koagulopathien.