The effect of insulin-induced hypoglycemia and atropine on serum cationic trypsin-like immunoreactivity in man.
In seven healthy volunteers insulin-induced hypoglycemia caused a significant rise in free serum cationic trypsin-like immunoreactivity (CTLI), which could be blocked by atropine. Atropine alone significantly decreased the serum CTLI level. The inhibitory effect of atropine was augmented by insulin, which appears to be a peripheral inhibitor of the CTLI release from the pancreatic acinar cells.
D000328:Adult; D001285:Atropine / Q000494:pharmacology*; D001786:Blood Glucose / Q000032:analysis*; D002412:Cations; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007328:Insulin / Q000494:pharmacology*; D008297:Male; D014357:Trypsin / Q000097:blood* / Q000276:immunology
D001786:Blood Glucose; D002412:Cations; D007328:Insulin; D001285:Atropine; D014357:Trypsin