[Interaction of low density lipoproteins with charged ligands: a study using the fluorescent probe 1-aniline naphthalene-8-sulfonate].
Heparin, chodroitin sulfates A, B, C, clofibrate and its derivatives as well as diphenyl disulfonate substituted the fluorescent probe I-aniline naphthalene-8-sulfonate in blood plasma low density lipoproteins. Constants of association for complexes of low density lipoproteins-heparin and chondroitin sulfate C, calculated on the basis of these data, were equal to 1.15.10(6) and 0,46.10(6) M-1, respectively. At the some time, the ligands studied altered the lipoprotein charges.
D002807:Chondroitin / Q000031:analogs & derivatives*; D002809:Chondroitin Sulfates / Q000378:metabolism*; D002994:Clofibrate / Q000378:metabolism*; D003871:Dermatan Sulfate / Q000378:metabolism*; D005456:Fluorescent Dyes; D006493:Heparin / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008024:Ligands; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008301:Maleimides; D011485:Protein Binding; D013050:Spectrometry, Fluorescence
D005456:Fluorescent Dyes; D008024:Ligands; D008077:Lipoproteins, LDL; D008301:Maleimides; D003871:Dermatan Sulfate; C010854:N-(1-anilinonaphthalyl)-4-maleimide; D006493:Heparin; D002807:Chondroitin; D002809:Chondroitin Sulfates; D002994:Clofibrate
Vzaimodeĭstvie lipoproteidov nizkoĭ plotnosti s zariazhennymi ligandami: issledovanie s pomoshch'iu fliuorestsentnogo zonda 1-anilinonaftalin-8-sul'fonata.