A study of the activity of soft soaps prepared from a homologous series of saturated fatty acids against cells of Escherichia coli NCTC 9001.
Soaps were prepared by direct neutralization of a homologous series of fatty acids with potassium hydroxide, the acids used being lauric, myristic palmitic and stearic acids. The antibacterial activity of these soaps were studied using Escherichia coli as the test organism. From the various phenomena examined it can be concluded that all the soaps used had a measure of antibacterial activity, the order of this activity being myristate, laurate, palmitate, and stearate. The antibacterial activity of both the palmitate and the stearate can only be described as marginal.
D000167:Acriflavine / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D005227:Fatty Acids / Q000494:pharmacology*; D009391:Nephelometry and Turbidimetry; D012915:Soaps / Q000494:pharmacology*; D013501:Surface-Active Agents / Q000494:pharmacology*
D005227:Fatty Acids; D012915:Soaps; D013501:Surface-Active Agents; D000167:Acriflavine