Autoradiographic analysis of FSH binding during follicular atresia.
Binding of FSH to ovarian cells was studied in PMSG primed immature Swiss mice, 48 h after PMSG treatment, FSH-binding was higher in the periphery than in the cumulus cells of the antral follicles. Binding of FSH to granulosa cells of normal follicles was observed to be specific, 48 h after PMSG injection. No localization in the atretic follicles could be seen by autoradiography 72 h after priming.
D000818:Animals; D001345:Autoradiography; D001665:Binding Sites / Q000187:drug effects; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006064:Gonadotropins, Equine / Q000494:pharmacology; D007457:Iodine Radioisotopes; D051379:Mice; D008815:Mice, Inbred Strains; D006080:Ovarian Follicle / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors
D006064:Gonadotropins, Equine; D007457:Iodine Radioisotopes; D005640:Follicle Stimulating Hormone