The effect of 5-fluorocytosine on the temperature profile of Candida albicans.
The temperature association of exponential thermal death with exponential growth, observed in a strain of Candida albicans, was disrupted by 5-fluorocytosine which, at a concentration of 2 micrograms ml-1, shifted the maximum temperature for growth from 38 degrees C to 33 degrees C but did not affect thermal death.
D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D003596:Cytosine / Q000031:analogs & derivatives*; D005437:Flucytosine / Q000494:pharmacology*; D013696:Temperature
D003596:Cytosine; D005437:Flucytosine