Foeto-maternal morbidity in the presence of antibodies to Trypanosoma cruzi.
Pregnancy outcome and maternal morbidity were analysed in 302 pregnant women with positive Machado-Guerreiro Complement Fixation Test (MGCFT) for antibodies to Trypanosoma cruzi and 302 women with a negative MGCFT resident of Córdoba, Argentina. A comparison of positive and negative cases was employed to investigate the association between MGCFT reaction and pregnancy outcome assessed from abortion and perinatal infant mortality rates; similarly, the data were analysed for demographic and socio-economic factors, numbers of previous pregnancies (birth order) and maternal complications. A twofold increase in the risk of pregnancy loss associated with a positive MGCFT was found. The incidence of polyhydramnios and varicosities of the leg was significantly higher in the serologically reactive group.
D000022:Abortion, Spontaneous / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis; D001722:Birth Order; D014355:Chagas Disease / Q000150:complications*; D003168:Complement Fixation Tests; D005260:Female; D005313:Fetal Death / Q000209:etiology; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008423:Maternal Age; D008875:Middle Aged; D010298:Parity; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012959:Socioeconomic Factors; D014349:Trypanosoma cruzi / Q000276:immunology
D000906:Antibodies