Bithorax phenocopy and pattern formation. II. A model of prepattern formation.
Phenocopy maps are constructed from the spatial pattern of the phenocopy spots using a distance function defined on the frequencies with which two compartments transform separately and jointly. The temporal changes in distances between different compartments in turn enable us to make inferences concerning the diffusion-like processes involved in prepattern formation of the metathorax. A model is presented which accounts for the data in terms of the propagation of two wavefronts in sequence and in approximately orthogonal directions. Sensitivity to transformation by ether is limited in time to the interval between the passing of the two wavefronts. Changes caused by 13 successive generations of ether treatment can be interpreted in terms of alterations in the timing and rates of wave propagation. A comparison of phenocopy and fate maps suggests that the prepatterning processes affect primarily the blastoderm cytoplasm or surface membrane.
D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects / Q000196:embryology* / Q000235:genetics; D005019:Ethyl Ethers / Q000494:pharmacology; D008954:Models, Biological; D009024:Morphogenesis / Q000187:drug effects; D010641:Phenotype; D013997:Time Factors
D005019:Ethyl Ethers