[P. falciparum malaria contracted in Burundi, resistant to chloroquine and diminished sensitivity to quinine].
The authors report a case of malaria from Burundi, due to chloroquine resistant Plasmodium falciparum. It is the second case of chloroquine resistance, confirmed by in vitro tests, in this country. Decreased sensitivity to quinine is demonstrated by in vivo study, and quinine assay. The isolate was sensitive to amodiaquine and mefloquine in vitro.
D000818:Animals; D002063:Burundi; D002738:Chloroquine / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000187:drug effects*; D011803:Quinine / Q000627:therapeutic use*
D002738:Chloroquine; D011803:Quinine
Paludisme à P. falciparum résistant à la chloroquine et de sensibilité diminuée à la quinine contracté au Burundi.