Changes in leukocyte count, blood glucose and coagulation system in calves injected with Escherichia coli endotoxin.
Responses of leukocyte, blood glucose and coagulation system in calves were investigated to injection with Escherichia coli endotoxin. Severe leukopenia and hyperglycemia following transient hypoglycemia were noted within 24 hours after injection. In the coagulation system, a definite decrease in platelet count, prolongation of prothrombin time and activated partial thromboplastin time were observed. Fibrinogen, soluble fibrin monomer complex and clotting time, however, varied.
D000818:Animals; D001777:Blood Coagulation; D001786:Blood Glucose / Q000032:analysis*; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood*; D004731:Endotoxins / Q000633:toxicity*; D004926:Escherichia coli; D005340:Fibrinogen / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary*; D010314:Partial Thromboplastin Time / Q000662:veterinary; D010976:Platelet Count / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary
D001786:Blood Glucose; D004731:Endotoxins; D005340:Fibrinogen