[Effect of dissolved carbon dioxide on the tetracycline biosynthesis process in an industrial fermenter].
The data on changes in the partial pressure of carbon dioxide (pCO2) dissolved in the fermentation broth in the course of biosynthesis of tetracycline made in a 63 m3 fermenter are presented. It is shown that pCO2 equal approximately to 2 cPa was optimal for tetracycline biosynthesis. The total carbonate concentration and pCO2 were estimated simultaneously in the process of tetracycline fermentation.
D002245:Carbon Dioxide / Q000494:pharmacology*; D005285:Fermentation / Q000187:drug effects*; D010313:Partial Pressure; D012996:Solutions; D013304:Streptomyces aureofaciens / Q000187:drug effects / Q000378:metabolism; D013752:Tetracycline / Q000096:biosynthesis*; D013997:Time Factors
D012996:Solutions; D002245:Carbon Dioxide; D013752:Tetracycline
Issledovanie vliianiia rastvorennogo yglekislogo gaza na protsess biosinteza tetratsiklina v promyshlennom fermentatore.