[Protection of mice by trehalose dimycolate against lethal infection by Trypanosoma cruzi].
Four weekly injections of 50 micrograms of trehalose dimycolate (TDM) in FIA protect 40% of the Mice against a lethal infection by Trypanosoma cruzi; under the same conditions MDP (muramyldipeptide) has only a very slight effect.
D000818:Animals; D014355:Chagas Disease / Q000517:prevention & control*; D003311:Cord Factors / Q000627:therapeutic use*; D006017:Glycolipids / Q000627:therapeutic use*; D051379:Mice; D008815:Mice, Inbred Strains
D003311:Cord Factors; D006017:Glycolipids
Protection de souris par le dimycolate de tréhalose (tdm) contre une infection létale par Trypanosoma cruzi.