Ciramadol, a new potent analgesic, used intravenously in renal colic.
In an open investigation, ciramadol, a partial agonist of opioid, was found to be a potent analgesic when 20 mg was given intravenously to 30 patients experiencing severe pain of renal colic. Total pain relief was obtained in 9 patients, while very good pain relief was obtained in 17 others. However, severe pain was experienced again in 7 of them after 1 to 2 hours. Vomiting and nausea occurred in 9 patients, and dizziness was present in 7 patients. The haemodynamic equilibrium was not changed by the analgesic.
D000328:Adult; D000588:Amines / Q000627:therapeutic use*; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001596:Benzylamines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003085:Colic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007674:Kidney Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D000588:Amines; D000700:Analgesics; D001596:Benzylamines; C018273:ciramadol