Angiosarcoma developing around a foreign body.
An 86-year-old World War I veteran developed an angiosarcoma at the site of a war wound. The tumour developed in relation to one of several metal grenade fragments. The tumour cells have been shown to contain blood coagulation factor VIII antigen and have features of endothelial cells on electron microscopy. The patient is claimed to be the last soldier dying of wounds sustained during that war, and to have the longest disease-free interval between injury and the onset of complications.
D000368:Aged; D000941:Antigens / Q000032:analysis; D001753:Blast Injuries / Q000150:complications*; D005169:Factor VIII / Q000276:immunology; D005547:Foreign Bodies / Q000150:complications*; D006394:Hemangiosarcoma / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008297:Male; D013899:Thoracic Neoplasms / Q000209:etiology* / Q000276:immunology / Q000473:pathology
D000941:Antigens; D005169:Factor VIII