Postincision steps of photoproduct removal in a mutant of Bacillus cereus 569 that produces UV-sensitive spores.
An excision-defective mutant of Bacillus cereus 569 is normal in incision and repair synthesis, but rejoining of incision breaks is defective, resulting in accumulation of low-molecular-weight DNA after UV irradiation. The defect in removal of photoproducts by exonuclease after incision renders both vegetative cells and dormant spores of the mutant sensitive to UV. A similarity is indicated to the uvrD mutation described recently in Escherichia coli.
D001409:Bacillus cereus / Q000235:genetics / Q000528:radiation effects*; D004261:DNA Replication / Q000528:radiation effects*; D004271:DNA, Fungal / Q000235:genetics / Q000302:isolation & purification / Q000528:radiation effects; D009154:Mutation; D013045:Species Specificity; D013171:Spores, Bacterial / Q000528:radiation effects; D014466:Ultraviolet Rays
D004271:DNA, Fungal