Behavioral and clinical profiles of Tourette's disease: a comprehensive overview.
A brief review of Gilles de la Tourette's disease is presented. The initial part gives an overview of major signs, symptoms displayed, and diagnosis in addition to certain minor concomitant features. The latter conditions included appetite, adaptive function, learning disorders, sexual behavior, sleep disturbances, speech pathology, and tic-related injury. Neurological manifestations, infectious etiology, and genetics were discussed. Treatment modalities are outlined and description of various drug therapy is given in conjunction with rationale of pharmacotherapy and possible underlying mechanism of action. Drug-induced Tourette's-like syndrome was also summarized.
D000109:Acetylcholine / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D016651:Lithium Carbonate; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D005879:Tourette Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D016651:Lithium Carbonate; D012701:Serotonin; D005680:gamma-Aminobutyric Acid; D008094:Lithium; D000109:Acetylcholine; D004298:Dopamine; D009638:Norepinephrine