[Determination of the antiactivator activity in human and animal blood plasma using tissue plasminogen activator].
An antiactivatory effect was estimated in blood plasma of human donors, rats and dogs on plates of stabilized fibrin using tissue plasminogen activator from pig heart. Inhibition of the tissue activator, used at definite concentrations, was expressed in per cents. The antiactivatory effect was distinctly higher in rat blood plasma, whereas it was similar in human and dog blood plasma, being about 3-fold decreased as compared with rats. The antiactivatory effect did not correlate with the antiactivator content in all the blood plasma preparations studied.
D000818:Animals; D004285:Dogs; D005337:Fibrin / Q000502:physiology*; D006023:Glycoproteins / Q000097:blood*; D006321:Heart / Q000502:physiology; D006801:Humans; D007700:Kinetics; D010960:Plasminogen Activators / Q000037:antagonists & inhibitors*; D015849:Plasminogen Inactivators; D051381:Rats; D013045:Species Specificity; D013552:Swine
D006023:Glycoproteins; D015849:Plasminogen Inactivators; D005337:Fibrin; D010960:Plasminogen Activators
Opredelenie antiaktivatornoĭ aktivnosti plazmy krovi cheloveka i zhivotnykh s tkanevym aktivatorom plazminogena.