[Increase in the production of oncovirus type C by an L929 cell culture as a result of BCG infection].
The effect of BCG infection of L929 cells on replication of oncovirus type C was studied. Ultrathin sections of the BCG-infected culture were examined electron microscopically 1, 3, 6, 8, and 10 days postinfection. Most microorganisms with the morphology typical of mycobacteria were found inside phagosomes. The number of extracellular virions as well as budding and abnormal forms per one cell contour was counted. BCG-infected cells were found to produce significantly more virus than the controls. The difference was maximal 3 days postinoculation. Possible reasons for the increased oncovirus production by continuous cell lines after infection with BCG are discussed.
D000818:Animals; D007739:L Cells / Q000382:microbiology* / Q000648:ultrastructure; D008247:Lysosomes / Q000382:microbiology / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron; D009163:Mycobacterium bovis / Q000472:pathogenicity* / Q000648:ultrastructure; D010587:Phagocytosis; D012190:Retroviridae / Q000502:physiology* / Q000648:ultrastructure; D013997:Time Factors; D014771:Virion / Q000648:ultrastructure; D014779:Virus Replication
Uvelichenie produktsii onkovirusa tipa C keltochnoĭ kul'turoĭ L929 v rezul'tate ee infitsiroavniia BTsZh.