Alcohol, lipids and heart disease.
The attenuating effect of moderate amounts of alcohol on cardiovascular morbidity and mortality has been reported by several groups of investigators at various geographic locations. At this time, the generally accepted explantation for this cardioprotective effect favors an increase in plasma high-density lipoprotein cholesterol, a factor inversely associated with the development of coronary heart disease (CHD). Other variables potentially influencing the development of CHD such as a reduced tendency for blood coagulation and increased fibrinolytic activity has been enhanced by alcohol and may be considered as possible additional mechanisms for the cardioprotective effects of the agent. Because of its addictive potential, alcohol should not be considered for treatment of CHD.
D000428:Alcohol Drinking; D000818:Animals; D001158:Arteries / Q000378:metabolism; D001777:Blood Coagulation / Q000187:drug effects; D002118:Calcium / Q000378:metabolism; D003327:Coronary Disease / Q000517:prevention & control*; D000431:Ethanol / Q000009:adverse effects / Q000494:pharmacology*; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D051381:Rats
D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D000431:Ethanol; D002118:Calcium