Chronic benign idiopathic neutropenia in Jordanians.
Bone marrow granulocyte reserves and the bone marrow storage pool were evaluated in 10 Jordanian adult patients with chronic benign idiopathic neutropenia, by measurement of the peripheral blood granulocyte increment following the administration of hydrocortisone and lithium. The increment in each case was statistically significant, indicating retention of effective neutrophil production in stressful situations and thus the benignity of this disorder.
D000293:Adolescent; D000328:Adult; D000380:Agranulocytosis / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D007597:Jordan; D008094:Lithium / Q000008:administration & dosage; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000097:blood* / Q000453:epidemiology
D016651:Lithium Carbonate; D008094:Lithium; D006854:Hydrocortisone