[Results of a clinical study of the Hungarian preparation Imodium].
The results from the clinical study on the preparation Imodium, production of the Hungarian firm "Gedeon Richter"--Budapest, are reported. The drug was tried on 53 patients with chronic and acute diarrheal syndrome chronic or acute enterocolitis, ulcerous colitis-- ChUHC, dyskinesia coli, biliary-colic fistula, Crohn's disease, gastric carcinoma with diarrheal syndrome, postresectional syndrome and some other diseases) with a very good result. The feces of the greater part of the patients normalized their consistence after the treatment of half to 10 days with a dose 6-8 mg daily, and their defecations were reduced to 1-2 for 24 h. In II patients an initial constipation occurred that was eliminated with the discontinuation of the preparation. Very good effect was attained in 37 and good in 16 patients. Furthermore, the preparation was very well tolerated and no adverse effects were observed. The good and rapid effect of Imodium developed in the majority of the patients observed, in 21 of the patients (42%) its effect was realized in half to two days, and in 19 of the patients (35%)--to 5 days, and in the rest 23%--from 6 to 10 days.
D000328:Adult; D000368:Aged; D000930:Antidiarrheals / Q000627:therapeutic use*; D002214:Capsules; D002986:Clinical Trials as Topic; D003672:Defecation / Q000187:drug effects; D003967:Diarrhea / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008139:Loperamide / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use*; D012996:Solutions; D013997:Time Factors
D000930:Antidiarrheals; D002214:Capsules; D010880:Piperidines; D012996:Solutions; D008139:Loperamide
Rezultati ot klinichnoto prouchvane na ungarskiia preparat imodium.