Selection of variants of Gram-negative bacteria with elevated production of type 1 beta-lactamase.
Variants of Pseudomonas aeruginosa, Citrobacter freundii and Enterobacter cloacae were isolated that produced elevated levels of type 1 beta-lactamase. The variants were readily isolated on antibiotic-containing agar and showed resistance to a wide range of beta-lactam antibiotics including some regarded as being relatively stable to the beta-lactamase produced.
D001419:Bacteria / Q000201:enzymology*; D002954:Citrobacter / Q000201:enzymology; D004754:Enterobacter / Q000201:enzymology; D011550:Pseudomonas aeruginosa / Q000201:enzymology; D001618:beta-Lactamases / Q000032:analysis*
D001618:beta-Lactamases