Thrombocytopenia in renal transplantation. Diagnostic use of homologous platelet labelling with 111In oxine.
We have used homologous platelet labelling with 111In oxine in the diagnosis of thrombocytopenia occurring in a patient who had received two renal transplants. The technique enabled us to prove that platelet destruction was occurring in the right-sided, non-functioning transplant. In the presence of moderately impaired bone marrow function, this destructive process was sufficient to cause thrombocytopenia. Transplant nephrectomy relieved the thrombocytopenia.
D001792:Blood Platelets; D002470:Cell Survival; D005260:Female; D006084:Graft Rejection; D006801:Humans; D006912:Hydroxyquinolines; D007204:Indium; D016030:Kidney Transplantation; D008875:Middle Aged; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives; D010976:Platelet Count; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013921:Thrombocytopenia / Q000000981:diagnostic imaging / Q000209:etiology*
D006912:Hydroxyquinolines; D009942:Organometallic Compounds; D011868:Radioisotopes; D007204:Indium; C032950:indium oxine; D015125:Oxyquinoline