[Interaction of radiographic contrast media with immunoglobulins].
As a special form of contrast medium incidents, various reaction modes between iodinated contrast media and immunoglobulins are described. Theoretical explanations and typical examples are given for each of the four different possible action mechanisms. Diagnostic precautions are proposed in order to avoid unfavourable reactions especially with paraproteins. Special attention is drawn to the antigen-antibody like reaction between iodinated contrast media and IgM paraproteins. Some immunological criteria are recalled to attention, this type of reaction has to meet stringently. Only by this, misinterpretation of inevident conclusions from analogy can be prevented in future similar cases.
D000937:Antigen-Antibody Reactions; D001536:Bence Jones Protein / Q000378:metabolism; D001809:Blood Viscosity / Q000187:drug effects; D003167:Complement Activation / Q000187:drug effects; D003287:Contrast Media / Q000009:adverse effects*; D003450:Cryoglobulins / Q000378:metabolism; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007457:Iodine Radioisotopes / Q000378:metabolism; D010266:Paraproteins / Q000378:metabolism
D003287:Contrast Media; D003450:Cryoglobulins; D007136:Immunoglobulins; D007457:Iodine Radioisotopes; D010266:Paraproteins; D001536:Bence Jones Protein
Die Reaktion von Röntgenkontrastmitteln mit Immunglobulinen.