[Use of methods of 2-dimensional electrophoresis in population genetics].
The review of literature on application of the methods of two-dimensional electrophoresis according to O'Farrel, in population genetics and in some adjacent fields of biology, is presented. Resolution capacities of both conventional and two-dimensional electrophoresis are briefly characterized. Data on application of two-dimensional electrophoresis methods for evaluation the degree of inter- and intraspecific variability, for detection and characterization of mutations, as well as for analysis of molecular mechanisms of inborn pathology are reviewed.
D000483:Alleles; D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics; D004586:Electrophoresis / Q000379:methods*; D005821:Genetic Techniques; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D007525:Isoelectric Focusing / Q000379:methods; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics; D009153:Mutagens / Q000494:pharmacology; D009154:Mutation; D011506:Proteins / Q000032:analysis / Q000235:genetics; D013045:Species Specificity
D009153:Mutagens; D011506:Proteins
Primenenie metodov dvumernogo élektroforeza v populiatsionnoĭ genetike.