[Kanamycin concentrations in liver tissue and bile in acute experimental cholecystocholangiohepatitis].
The levels of kanamycin in the bile and liver tissue were studied on 10 healthy dogs and 10 dogs with experimental acute abacterial cholecystocholangiohepatitis. It was shown that bile excretion of kanamycin in the dogs increased 6-7 times with development of acute inflammation in the biliary system.
D000208:Acute Disease; D000818:Animals; D001646:Bile / Q000378:metabolism*; D001682:Biological Availability; D002761:Cholangitis / Q000188:drug therapy*; D002764:Cholecystitis / Q000188:drug therapy*; D004285:Dogs; D004927:Escherichia coli Infections / Q000188:drug therapy*; D006505:Hepatitis / Q000188:drug therapy*; D007612:Kanamycin / Q000378:metabolism* / Q000627:therapeutic use; D007700:Kinetics; D008099:Liver / Q000378:metabolism*
D007612:Kanamycin
Soderzhanie kanamitsina v tkani pecheni i zhelchi pri ostrom eksperimental'nom kholetsistokholangiogepatite.