An anastomotic device for microvascular surgery: evolution.
A new anastomotic device is demonstrated that is suitable in microvascular surgery for repairing severed blood vessels and inserting vein grafts. Initial pilot studies indicate a 100% patency rate for vessel anastomosis, and a one-year study produced a 96% success rate. However, histological examination revealed notable vessel deterioration with a rigid device. Therefore, an absorbable anastomotic coupler was developed that demonstrates a high patency rate (92%) in both arteries and veins, with substantial absorption of the device by 70 days. Healing at the anastomotic site was qualitatively similar to that obtained with a sutured anastomosis; there was endothelialization by 14 days and absorption of the device by 70 days.
D000818:Animals; D002339:Carotid Arteries / Q000473:pathology; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D008297:Male; D008866:Microsurgery / Q000266:history / Q000295:instrumentation / Q000379:methods*; D010865:Pilot Projects; D011108:Polymers / Q000627:therapeutic use; D011817:Rabbits; D013450:Sulfones / Q000627:therapeutic use; D013536:Suture Techniques / Q000266:history
D011108:Polymers; D013450:Sulfones