[The effect of Pseudomonas aeruginosa exotoxin on various nonspecific factors of immunologic reactivity in an experiment].
The main characteristics of the nonspecific responsiveness of the body have been studied on the model of acute P. aeruginosa intoxication. An increase in phagocytic and lysozyme activity and in the bactericidal properties of blood serum have been shown to occur during the first 6 hours after the introduction of P. aeruginosa exotoxin. The titer of complement and beta-lysin activity decrease. At a later period of observations a sharp drop in all the characteristics under study (except lysozyme activity) occurs.
D000818:Animals; D001770:Blood Bactericidal Activity; D003165:Complement System Proteins / Q000032:analysis; D005098:Exotoxins / Q000276:immunology*; D007113:Immunity, Innate; D008239:Lysine / Q000097:blood / Q000031:analogs & derivatives; D010587:Phagocytosis; D011552:Pseudomonas Infections / Q000276:immunology*; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D011817:Rabbits
D005098:Exotoxins; C065591:beta-lysine; D003165:Complement System Proteins; D008239:Lysine
Vliianie ékzotoksina Pseudomonas aeruginosa na nekotorye nespetsificheskie faktory immunologicheskoĭ reaktivnosti organizma v éksperimente.