Ovarian disease in childhood lymphoblastic leukaemia.
A 3-year-old child is described with an ovarian relapse arising 2 years after starting treatment for 'common' lymphoblastic leukaemia. This, considered with previously described cases, suggests that ovarian disease can arise as a late complication in girls without poor prognostic features at diagnosis, and may be associated with meningeal infiltration.
D001932:Brain Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D002675:Child, Preschool; D003561:Cytarabine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D007945:Leukemia, Lymphoid / Q000150:complications*; D008727:Methotrexate / Q000008:administration & dosage; D010051:Ovarian Neoplasms / Q000209:etiology*
D003561:Cytarabine; D008727:Methotrexate