Influence of parenteral fat administration on the pulmonary vascular system in man.
In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was monitored before, during, and after the administration of Lipofundin S 20% (0.24 g/kg/h). In addition right ventricular stroke work index (RVSWI), alveolar-arterial oxygen difference (A-aDO2) and pulmonary shunt (Qs/Qt) were calculated. The results indicate that there are no changes of the PAP, the RVSWI, and the A-aDO2 during the period of observation.
D000328:Adult; D000368:Aged; D005217:Fat Emulsions, Intravenous; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition; D011651:Pulmonary Artery / Q000502:physiology; D011652:Pulmonary Circulation; D014947:Wounds and Injuries / Q000503:physiopathology / Q000628:therapy*
D005217:Fat Emulsions, Intravenous