[Anti-Thomsen-Friedenreich (anti-T) antibody titer in kidney transplant recipients].
In 43 recipients of allogenic cadaver kidneys before and three times a week after transplantation to the discharge from the hospital care the antibody titre against the Thomsen-Friedenreich-antigen (Anti-T) was determined and the score value was calculated from the agglutination intensity. A prognostic significance of the value got before operation could not be found. No changes of the titre appeared under the influence of the postoperatively performed immunosuppression as well as in connection with rejection crises. In 9 patients with clinically manifest systemic infections (8 cytomegalovirus infections, 1 bacterial infection) unequivocal (greater than or equal to 8 fold) increases of the anti-T-titre could be proved. These findings speak for an infection-induced formation of these cross-reacting anti-T-antibodies.
D000293:Adolescent; D000328:Adult; D000372:Agglutination Tests; D000906:Antibodies / Q000032:analysis*; D002648:Child; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007676:Kidney Failure, Chronic / Q000276:immunology / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011379:Prognosis
D000906:Antibodies; C025991:Thomsen-Friedenreich antibodies
Anti-Thomsen-Friedenreich- (Anti-T-) Antikörpertiter bei Nierentransplantatrezipienten.