Assembly of Rickettsia tsutsugamushi progeny in irradiated L cells.
In the assembly of Rickettsia tsutsugamushi progeny in irradiated L cells, nascent forms first appear as undemarcated foci in the host cell granular cytoplasm, in which electron-lucent filamentous (f) and electron-dense granular (g) areas differentiate. Morphological observations indicated that the assembly involves formation of a filamentous network in the f area, manufacture of rickettsial ribosomes in the g area, and formation of mildly electron-dense fuzzy zones, along which a double membrane assembles.
D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D003593:Cytoplasm / Q000382:microbiology*; D007739:L Cells / Q000382:microbiology*; D051379:Mice; D008854:Microscopy, Electron; D009024:Morphogenesis; D012285:Orientia tsutsugamushi / Q000254:growth & development* / Q000648:ultrastructure; D012270:Ribosomes / Q000378:metabolism / Q000648:ultrastructure