Cell-bound gold (CBG) in patients treated with aurothioglucose and with auranofin. A comparison of different methods of determination.
Three different methods of determining the cell-bound gold concentration were compared in patients given intramuscular and oral chrysotherapy for rheumatoid arthritis. We found a strong correlation between the different methods and no difference between 2 washing procedures.
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000097:blood* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001310:Auranofin; D006051:Aurothioglucose / Q000031:analogs & derivatives* / Q000097:blood* / Q000627:therapeutic use; D001665:Binding Sites; D001793:Blood Preservation; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D006046:Gold / Q000031:analogs & derivatives* / Q000097:blood*; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D013048:Specimen Handling; D013054:Spectrophotometry, Atomic
D000893:Anti-Inflammatory Agents; D006051:Aurothioglucose; D001310:Auranofin; D006046:Gold