Organ transplantation with special emphasis on Cyclosporin A.
The history of organ transplantation and the development of immunosuppression therapy were discussed in detail, starting from Medawar's acquired immunological tolerance theory. The current status of transplantation of organs including the kidney, heart, liver and pancreas was reviewed. Current concepts of immunosuppression were discussed, with special emphasis on the use of Cyclosporin A.
D000818:Animals; D002170:Canada; D003524:Cyclosporins; D005060:Europe; D016027:Heart Transplantation; D049672:History, 19th Century; D049673:History, 20th Century; D049691:History, Medieval; D006801:Humans; D007165:Immunosuppression Therapy / Q000266:history*; D016030:Kidney Transplantation; D016031:Liver Transplantation; D016035:Pancreas Transplantation; D014180:Transplantation / Q000266:history*; D014481:United States
D003524:Cyclosporins