Cloning and sequence analysis of two monkey metallothionein cDNAs.
We have isolated two metallothionein (MT) cDNA clones copied from the RNA of cadmium-resistant monkey kidney cells. The complete DNA sequences of these clones show that they encode two distinct MTs. One clone appears to represent monkey MT-II, as shown by its close homology to the human MT-II sequence, whereas the second may correspond to monkey MT-I or a related variant metallothionein. Conserved sequences were identified in both the 5' and 3' untranslated regions of these clones.
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002460:Cell Line; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D005796:Genes; D000882:Haplorhini / Q000235:genetics; D008668:Metallothionein / Q000235:genetics*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics*
D012333:RNA, Messenger; D004247:DNA; D008668:Metallothionein