Characterization of pepsin-resistant peptides present in a glycoprotein isolated from lung lavage of normal rabbit.
A glycoprotein of Mr 36 000 has been isolated from lung lavage of normal rabbit and purified to homogeneity by gel chromatography. Three peptides containing hydroxyproline and nearly 30% glycine have been isolated and purified from pepsin-digested native glycoprotein. Partial NH2-terminal amino acid sequence analysis on one of the peptides indicated the presence of -Gly-Pro-Hyp-Gly- sequence in the peptide chain, suggesting that collagen-like region(s) may be present in this glycoprotein.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D006023:Glycoproteins / Q000302:isolation & purification*; D008168:Lung / Q000032:analysis*; D008970:Molecular Weight; D010434:Pepsin A; D010455:Peptides / Q000302:isolation & purification*; D011817:Rabbits
D000596:Amino Acids; D006023:Glycoproteins; D010455:Peptides; D010434:Pepsin A