Crimean-congo hemorrhagic fever in South Africa.
Crimean-Congo hemorrhagic fever virus was isolated for the first time in South Africa in February 1981, from the blood of a 13-year-old boy who died in Johannesburg after attending a camp in a nature reserve in the western Transvaal. Virus was isolated from 21/120 pools of questing ticks from the nature reserve, the infected species being Hyalomma marginatum rufipes and H. truncatum. Virus was also isolated from 4/38 pools of partially engorged ticks and other ectoparasites collected off hosts, the infected species being H.m. rufipes, H. truncatum and Rhipicephalus evertsi. Antibodies were found in the sera of 5/74 humans, 8/26 wild vertebrates, 74/270 sheep, and 109/170 cattle from the reserve and surrounding farms. Antibodies were also found in 28/200 hares from various locations in the country. It was concluded that the virus is widely prevalent in South Africa, but the full medical and veterinary significance of its presence has yet to be determined.
D000293:Adolescent; D000818:Animals; D000835:Animals, Wild / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis; D002043:Bunyaviridae / Q000302:isolation & purification*; D002417:Cattle / Q000276:immunology; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000276:immunology / Q000302:isolation & purification*; D006479:Hemorrhagic Fever, Crimean / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D012756:Sheep / Q000276:immunology; D013019:South Africa; D013987:Ticks / Q000382:microbiology*
D000914:Antibodies, Viral