[Vascular factors in the pathogenesis of pre-eclampsia: recent findings].
Normal, rigid and fibrotic utero-placental arteries are resistant to the action of circulating vaso-motor substances. In contrast, the persistence and the hyperplasia of smooth muscle fibres result in a reduced flow in the intervillous compartment and a sensitivity of the vessels to vaso-constrictor substances. These lesions, which develop after the twentieth week, provide the necessary conditions for the subsequent development of the characteristic vicious cycles of eclampsia.
D001158:Arteries / Q000276:immunology / Q000473:pathology; D003176:Complement C3 / Q000032:analysis; D005260:Female; D005337:Fibrin / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D006965:Hyperplasia; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000098:blood supply*; D011225:Pre-Eclampsia / Q000209:etiology* / Q000276:immunology; D011247:Pregnancy; D014599:Uterus / Q000098:blood supply*
D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005337:Fibrin
La participation vasculaire dans la pathogénie de la pré-éclampsie: acquisitions récentes.