The "in vivo" effect of chymopapain on intervertebral disc hernia (an ultrastructural study).
This is an ultrastructural study of disc material obtained from two patients subjected to operation two weeks after an unsuccessful chymonucleolysis. It confirms that the "in vivo" effects of chymopapain are similar to those observed "in vitro", namely that it is ineffective in large contained hernias and in extruded hernias.
D000328:Adult; D002917:Chymopapain / Q000494:pharmacology* / Q000627:therapeutic use; D010450:Endopeptidases / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000187:drug effects* / Q000648:ultrastructure; D007405:Intervertebral Disc Displacement / Q000628:therapy*; D008297:Male
D010450:Endopeptidases; D002917:Chymopapain