The role of complement in the induction of thromboplastin synthesis.
Complement appears to be an important system for cell activation in circulating blood. It is established that granulocytes may be stimulated through complement activation. In the present paper we propose also a central role of complement in the induction of thromboplastin synthesis in blood monocytes and endothelial cells.
D000937:Antigen-Antibody Reactions; D003167:Complement Activation; D003165:Complement System Proteins / Q000276:immunology / Q000502:physiology*; D004211:Disseminated Intravascular Coagulation / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004727:Endothelium / Q000378:metabolism; D004731:Endotoxins / Q000494:pharmacology; D006801:Humans; D009000:Monocytes / Q000276:immunology / Q000378:metabolism; D018805:Sepsis / Q000097:blood; D013925:Thromboplastin / Q000096:biosynthesis*
D004731:Endotoxins; D003165:Complement System Proteins; D013925:Thromboplastin