A comparison of pulsed ultrasound, radiography and micrometer screw gauge in the measurement of skin thickness.
Comparisons of ultrasonic, radiographic and micrometer methods in the measurement of skin thickness were made in 16 volunteers before and after 1-month's treatment with four clobetasol propionate formulations. Correlations between the methods were highly significant (r = 0.68 to 0.75). Correlations in the females were better than in the males suggesting that measurements in women are more easily made. Percentage reductions in skin thickness after steroid treatment were ranked in an identical order, whichever method was used. Each of the three methods, therefore, was shown to be effective. Ultrasound was the preferred technique but the micrometer screw gauge was shown to be a reasonable alternative.
D000328:Adult; D001284:Atrophy; D002990:Clobetasol / Q000009:adverse effects / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D012737:Sex Factors; D012867:Skin / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology*; D013997:Time Factors; D014463:Ultrasonography
D002990:Clobetasol