[Basic and clinical studies on serum CEA levels using a new CEA-EIA (double monoclonal) kit].
Serum CEA levels were measured in normal subjects and in patients with benign and malignant diseases using a new Abbott CEA-EIA (double monoclonal) kit. The results of basic and clinical studies indicated that the correlation coefficient between serum CEA levels measured by a polyclonal CEA kit and serum CEA levels by the new kit was r = 0.976, and the reproducibility, stability and simplicity of this new kit were superior. The CEA levels were 1.68 + 0.11 ng/ml in normal subjects, and significant differences were shown between the two sexes, 1.81 + 1.67 ng/ml in the patients with benign diseases and a true positive rate of more than 7.0 ng/ml CEA levels was seen in 24.1% of the patients with malignant diseases. High positive rates were observed in patients with neoplasms, of the biliary tract and pancreas, then the colon, esophagus and stomach.
D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000276:immunology*; D011933:Reagent Kits, Diagnostic / Q000592:standards; D012737:Sex Factors
D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen; D011933:Reagent Kits, Diagnostic