[Protein binding of steroids].
The role of protein-binding in the physiology of steroids is of great complexity. The following are envisaged: the types of protein, methods of binding and the affinity of steroids for proteins, and the variations in free fraction according to plasma protein levels; the functions of binding proteins on the activity and clearance of steroids as well as on the peripheral conversion of androgens; the factors which influence variations in binding protein levels and in particular the influence of circulating levels of natural hormones and the influence of hormone treatment.
D000328:Adult; D000728:Androgens / Q000502:physiology; D000735:Androstenedione / Q000378:metabolism; D000736:Androstenes / Q000097:blood / Q000378:metabolism*; D003276:Contraceptives, Oral / Q000494:pharmacology; D013196:Dihydrotestosterone / Q000378:metabolism; D045166:Estradiol Congeners / Q000494:pharmacology; D004963:Estrenes / Q000097:blood / Q000378:metabolism*; D004967:Estrogens / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011278:Pregnanes / Q000097:blood / Q000378:metabolism*; D045167:Progesterone Congeners / Q000494:pharmacology; D011372:Progestins / Q000494:pharmacology; D011388:Prolactin / Q000502:physiology; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism
D000728:Androgens; D000736:Androstenes; D003276:Contraceptives, Oral; D045166:Estradiol Congeners; D004963:Estrenes; D004967:Estrogens; D011278:Pregnanes; D045167:Progesterone Congeners; D011372:Progestins; D012709:Serum Albumin; D012738:Sex Hormone-Binding Globulin; D013196:Dihydrotestosterone; D013739:Testosterone; D000735:Androstenedione; D011388:Prolactin
Les liaisons protéiniques des stéroïdes.