Myeloid metaplasia of the breast. A lesion which clinically mimics carcinoma.
The authors report a case of myeloid metaplasia of the breast presenting as a tumor mass with homolateral axillary lymphadenopathy. The lesion was clinically misinterpreted as a breast cancer and developed in an elderly woman 8 years after the diagnosis of primary myelofibrosis was made. Immunohistochemical and ultrastructural studies confirmed the haematopoietic nature of the proliferating cells. The differential diagnosis from other breast lesions is discussed.
D000368:Aged; D001365:Axilla; D001941:Breast Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D055728:Primary Myelofibrosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*