[Determination of kidney clearance by reconstruction of the whole-body retention curves from later measurements].
Starting from routine renal clearance measurements in a partially shielded whole-body counter, generally applicable algorithms were developed empirically which permit the reconstruction of the total course of retention up to 28 min p.i. from e.g. the 12 min and 24 min values only. By formal differentiation the instantaneous slope of the decline in retention and thus the renal clearance can be calculated employing the whole-body counting principle. Integration yields the possibility of subtracting background from renograms to calculate single renal clearances. The method offers advantages in cases of reduced measurement geometry and/or low count rates.
D006801:Humans; D007465:Iodohippuric Acid / Q000378:metabolism; D007668:Kidney / Q000000981:diagnostic imaging / Q000378:metabolism*; D008433:Mathematics; D004369:Pentetic Acid / Q000378:metabolism; D011877:Radionuclide Imaging; D013667:Technetium / Q000378:metabolism; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors; D014915:Whole-Body Counting / Q000379:methods*
D007465:Iodohippuric Acid; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate
Bestimmung der Nierenclearance durch Rekonstruktion der Ganzkörperretentionskurve aus späteren Messwerten.