Effect of lithium therapy on glomerular filtration rate.
Patients taking lithium had a slightly higher serum creatinine concentration than controls. Creatinine concentration was independent of lithium level or therapy length, suggesting that lithium decreases glomerular filtration but that this effect is small, noncumulative, and of marginal clinical significance.
D000328:Adult; D001714:Bipolar Disorder / Q000097:blood / Q000188:drug therapy; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects*; D006801:Humans; D008094:Lithium / Q000494:pharmacology* / Q000627:therapeutic use; D016651:Lithium Carbonate; D008297:Male; D019964:Mood Disorders / Q000097:blood / Q000188:drug therapy
D016651:Lithium Carbonate; D008094:Lithium; D003404:Creatinine