[Anti-inflammatory activity of a copper complex carrying a sugar vector, and observed serum copper levels].
(N-2-amino-2-deoxy-alpha, beta-D-glucopyranose salicylaldimino)-Cu (II) shows an anti-inflammatory activity in the cotton wad granuloma on Rats. An increase of the copper level in serum is detected very soon after s.c. drug administration, which is due to the high diffusion of the complex.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000378:metabolism / Q000627:therapeutic use*; D003300:Copper / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use*; D006099:Granuloma / Q000188:drug therapy; D007279:Injections, Subcutaneous; D007700:Kinetics; D008297:Male; D009942:Organometallic Compounds / Q000378:metabolism / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains
C038899:(N-2-amino-2-deoxyglucose salicylaldimino)copper(II); D000893:Anti-Inflammatory Agents; D009942:Organometallic Compounds; D003300:Copper
Activité anti-inflammatoire d'un complexe de cuivre porteur du vecteur sucre et taux de cuivre sérique observés.