Failure of bupropion to affect prolactin or growth hormone in man.
In a double-blind crossover design, 5 male and 5 female volunteers received 5 different oral single-dose bupropion treatments (12.5 mg to 100 mg). Analyses of plasma prolactin and growth hormone levels revealed no significant drug related effects compared to placebo.
D000328:Adult; D000928:Antidepressive Agents / Q000494:pharmacology*; D016642:Bupropion; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D008297:Male; D010919:Placebos; D011388:Prolactin / Q000097:blood*; D011427:Propiophenones / Q000494:pharmacology*
D000928:Antidepressive Agents; D010919:Placebos; D011427:Propiophenones; D016642:Bupropion; D011388:Prolactin; D013006:Growth Hormone