Pancreatitis during sodium valproate treatment.
A girl aged 1 year died of acute haemorrhagic pancreatitis while taking sodium valproate. Necropsy showed widespread vascular disease that may have contributed to the onset of pancreatitis. Previous reports of pancreatitis in children receiving valproic acid are reviewed and although the association is rare, a causal relation between pancreatitis and valproic acid seems to have been established.
D000208:Acute Disease; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007223:Infant; D010195:Pancreatitis / Q000139:chemically induced*; D003294:Seizures, Febrile / Q000188:drug therapy; D014635:Valproic Acid / Q000009:adverse effects*
D014635:Valproic Acid