Comparison of side effects during cerebral computed tomography with a nonionic (iohexol) and an ionic (metrizoate) contrast medium.
Cerebral computed tomography was performed in 60 patients referred for pre- and postcontrast scanning. The patients were randomly sampled with a nonionic contrast medium, iohexol, and an ionic contrast medium, sodium metrizoate. No complications were seen, and the adverse effects, usually a feeling of warmth, were very minor with both contrast media, but iohexol caused less discomfort than sodium metrizoate. A series of measurements of the attenuation values of well defined intracranial structures was performed and no difference in enhancement was found between the two contrast media.
D001927:Brain Diseases / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000009:adverse effects*; D004311:Double-Blind Method; D006801:Humans; D007463:Iodobenzoates / Q000009:adverse effects*; D007472:Iohexol; D008794:Metrizoic Acid / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014283:Triiodobenzoic Acids / Q000009:adverse effects*
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008794:Metrizoic Acid