Effects of Na2CaEDTA on lead deposits in rabbit osseous tissue.
Radiochemical and autoradiographic methods were used for 210Pb determination after Na2CaEDTA administration to rabbits. 210Pb was determined in soft tissues, compact and trabecular bones and growing microareas on the endosteum of the long bone. After Na2CaEDTA injection lead was depleted from 'new' deposits mainly on the growing surface of both trabecular and compact bones.
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism*; D004492:Edetic Acid / Q000494:pharmacology*; D007855:Lead Poisoning / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D011817:Rabbits
D004492:Edetic Acid