[Effect of various drugs on peripheral hemodynamics in left-ventricular insufficiency in patients with chronic ischemic heart disease].
It is established that in the majority of patients at the height of left ventricular insufficiency (LVI) low cardiac output is not recorded, it is within the normal limits and at times even higher than normal. In isolated LVI present only with pulmonary hypertension, despite the absence of insufficiency of the right heart considerable disorders of peripheral haemodynamics are present in the shape of decreased volume of tissue blood flow, venous capacity and extensibility of the peripheral veins. The degree of this decrease is proportional to the severity of LVI and upset of the pulmonary circulation. The more persistent and considerable effect correcting decreased capacity and extensibility of the peripheral veins and enhancing the perfusion of tissues with isolated LVI is exerted by furosemide, nitroglycerine is somewhat less effective. Strophanthin exerts such effect in roughly 50% of cases, and obsidan is unreliable in its effect.
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003327:Coronary Disease / Q000503:physiopathology*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D013328:Strophanthins / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D013328:Strophanthins; D014665:Vasodilator Agents; D011433:Propranolol; D005996:Nitroglycerin
Sostoianie perifericheskoĭ gemodinamiki i vliianie na nee nekotorykh lekarstv pri levozheludochkovoi nedostatochnosti u bol'nykh khronicheskoĭ ishemicheskoĭ bolezn'iu serdtsa.