Myocardial preservation during anoxic arrest. Chemical cardioplegia.
Two types of cardioplegic solution--the potassium arrest and the Bretschneider solution, both at 4 degrees C--were compared with regard to protective effect against ischemic damage during 60 min of anoxic cardiac arrest in the dog heart. Both solutions provided equally good protection, which was superior to that given by hypothermia alone.
D000818:Animals; D002315:Cardiopulmonary Bypass; D004285:Dogs; D004562:Electrocardiography; D005947:Glucose / Q000494:pharmacology*; D006321:Heart / Q000502:physiology; D006324:Heart Arrest, Induced / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D006982:Hypertonic Solutions / Q000494:pharmacology*; D007036:Hypothermia, Induced; D008353:Mannitol / Q000494:pharmacology*; D009200:Myocardial Contraction / Q000187:drug effects; D011188:Potassium / Q000494:pharmacology*; D011189:Potassium Chloride / Q000494:pharmacology*; D017680:Potassium Compounds; D011343:Procaine / Q000494:pharmacology*
C039984:Bretschneider cardioplegic solution; D006982:Hypertonic Solutions; D017680:Potassium Compounds; C018369:potassium cardioplegic solution; D008353:Mannitol; D011343:Procaine; D011189:Potassium Chloride; D005947:Glucose; D011188:Potassium