Haemorrhage and factor IX deficiency in pituitary insufficiency.
Acquired isolated factor IX deficiency is rare. A case presenting with haemorrhage after dental extraction is described. The factor IX deficiency was associated with pituitary insufficiency and was completely corrected following the administration of thyroxine. This contrasts with a previously reported case in which both thyroxine and cortisone were required for complete correction of the factor IX deficiency. The underlying mechanism and the consequences are briefly discussed.
D002836:Hemophilia B / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000209:etiology; D013974:Thyroxine / Q000172:deficiency / Q000627:therapeutic use; D014081:Tooth Extraction / Q000009:adverse effects
D013974:Thyroxine