Is pulsed ultrasound mutagenic?
The possibility that microsecond pulses of 3 MHz ultrasound may interact at the cellular level, with genetic consequences, was investigated using two different endpoints. The Ames mammalian microsome test was employed to assess mutagenicity and viability in Salmonella typhimurium bacteria, while the sister chromatid exchange frequency provided an indicator of ultrasound induced effects at the chromosome level in Chinese hamster ovary cells.
D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D005260:Female; D009152:Mutagenicity Tests; D009154:Mutation; D010053:Ovary; D012486:Salmonella typhimurium / Q000235:genetics; D012854:Sister Chromatid Exchange; D014465:Ultrasonics / Q000009:adverse effects*