[Residual ovarian function after minidoses of estroprogestative agents].
Levels of plasma 17 beta oestradiol, FSH and LH, were carried out on the 7th, 14th, 21st and 28th day of the cycle in three studies in order to evaluate the residual ovarian secretions under the influence of low-dose pills (30 micrograms of ethinyl-oestradiol and 150 micrograms of levonorgestrel). The studies consisted of: a preliminary study involving 5 women under the oestrogen/progestogen pills over more than 1 year; a comparative study of the three first cycles on the same preparation against a control cycle (5 women); a comparative crossover study of one cycle of the minidose oestrogen/progestogen preparation and one cycle of oestrogen/progestogen preparation with 50 micrograms of ethinyl-oestradiol (10 women). The results of these trials show that minidose oestrogen/progestogen preparations have a braking effect on the hypophysio-ovarian axis similar to that exerted by the higher dose pills.
D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage; D004958:Estradiol / Q000097:blood; D004997:Ethinyl Estradiol / Q000008:administration & dosage*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D016912:Levonorgestrel; D009644:Norgestrel / Q000008:administration & dosage*; D010053:Ovary / Q000187:drug effects / Q000378:metabolism*
D003277:Contraceptives, Oral, Combined; D006065:Gonadotropins, Pituitary; D009644:Norgestrel; D004997:Ethinyl Estradiol; D004958:Estradiol; D016912:Levonorgestrel
Etude de la fonction ovarienne résiduelle sous estroprogestatifs minidosés.