[Treatment of corpus luteum insufficiency-induced functional sterility with clomiphene].
Two hundred and fifty-six women were treated with clomiphene citrate. As a consequence of treatment preovulatory FSH concentration of the serum increased. There was an improvement of the luteal function in 84.0% of the patients, and 53.9% of them became pregnant. Based on the above data the authors consider clomiphene citrate suitable for treatment of luteal dysfunction. In a number of cases clomiphene treatment proved to be effective even after failure of the gonadotropin treatment.
D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use*; D003338:Corpus Luteum / Q000187:drug effects / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000503:physiopathology; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood
D002996:Clomiphene; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D005640:Follicle Stimulating Hormone
Behandlung der durch Corpus-luteum-Insuffizienz bedingten funktionellen Sterilität mit Clomiphen.