Evaluation of left ventricular function by radionuclide angiography during exercise in normal subjects and in patients with chronic coronary heart disease.
Radionuclide angiography permits evaluation of left ventricular performance during exercise. There are several factors that may affect the results in normal subjects and in patients with chronic coronary heart disease. Important among these are the selection criteria: age, sex, level of exercise, exercise end points, ejection fraction at rest and effects of pharmacologic agents. An abnormal ejection fraction response to exercise is not a specific marker for coronary heart disease but may be encountered in other cardiac diseases. In addition to the diagnostic considerations, important prognostic data can be obtained. Further studies are needed to determine the prognostic implications of anatomic findings versus the functional abnormalities induced by exercise in patients with coronary artery disease.
D000367:Age Factors; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005080:Exercise Test; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D007537:Isometric Contraction; D005996:Nitroglycerin / Q000494:pharmacology; D005082:Physical Exertion; D011187:Posture; D011433:Propranolol / Q000494:pharmacology; D011877:Radionuclide Imaging; D012737:Sex Factors; D013318:Stroke Volume; D014700:Verapamil / Q000494:pharmacology
D011433:Propranolol; D014700:Verapamil; D005996:Nitroglycerin