[Polymorphic biochemical systems in the population of immigrant inhabitants of the northeastern USSR. I. The genetic structure and its heterogeneity due to sexual dimorphism and to the duration of separate groups living under extreme environmental conditions].
Analysis of frequencies of phenotypes and genes for 12 polymorphic loci of 2891 healthy inhabitants of Magadan showed that the frequencies are different in men and women (loci AcP, GPT, Tf), and in individuals selected according to various duration of dwelling under extreme conditions. Therewith, the "dynamics" of phenotype and gene frequencies is not synonymous to the representatives of both sexes. Confirmed are the previous data indicating that the formation of man's population in the extreme conditions entails changes in the genetic structure. The following are the most informative loci for revealing ecologically determined population heterogeneity: acid erythrocyte phosphatase (AcP); alkaline serum phosphatase (Pp); glyoxalase-I (GLO-I); group specific component (Gc) and blood groups Rh.
D000017:ABO Blood-Group System / Q000235:genetics; D000293:Adolescent; D000328:Adult; D000483:Alleles; D004641:Emigration and Immigration; D004782:Environmental Health; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D012204:Rh-Hr Blood-Group System / Q000235:genetics; D012727:Sex Characteristics; D012800:Siberia; D013997:Time Factors; D014505:Urban Population
D000017:ABO Blood-Group System; D012204:Rh-Hr Blood-Group System
Biokhimicheskie polimorfnye sistemy v populiats ii prishlykh zhiteleĭ Severo-Vostoka SSSR. Soobshchenie I. Geneticheskaia struktura i ee geterogennost', obuslovlennaia polovym dimorfizmom i dlitel'nost, iu prozhivaniia otdel'nykh grupp v ékstremal'nykh usloviiakh sredy.