Thalamic units firing upon refixation may be responsible for plasticity in visual cortex.
In alert cat and monkey, a unit type recorded in the region of the thalamic internal medullary lamina seems to provide the extraretinal signal postulated by Singer (1982) to explain the development of mature receptive field properties in cortical visual neurons. These thalamic units are silent (or silenced) during saccades in all directions; they discharge as soon as the eyes assume a new position. The abolition of this discharge by thalamic lesion, or conversely, its elicitation by electrical stimulation could respectively prevent or facilitate plastic changes in visual cortical areas of kittens.
D000818:Animals; D002415:Cats; D004553:Electric Conductivity; D004558:Electric Stimulation; D000882:Haplorhini; D009473:Neuronal Plasticity; D009474:Neurons / Q000502:physiology; D012438:Saccades; D013788:Thalamus / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*