Central venous catheter-induced endocarditis: human correlate of the animal experimental model of endocarditis.
A case of right-sided endocarditis clearly associated with the presence of a right atrial catheter is presented, and the literature on septicemia and endocarditis associated with central venous and pulmonary artery catheterization is reviewed. In the majority of cases of catheter-associated endocarditis reported in the literature, diagnosis has been made at autopsy; echocardiographic diagnosis has been reported only recently. The case presented in this report represents the only case in this literature in which the lesion causing right-sided endocarditis has been identified by two-dimensional echocardiogram and confirmed by tissue diagnosis. The mechanism of direct traumatization of the endocardium by the catheter makes central venous catheter-induced endocarditis bear pathophysiologic similarity to the experimental model of endocarditis in animals.
D000328:Adult; D000818:Animals; D002404:Catheterization / Q000009:adverse effects*; D002496:Central Venous Pressure; D004195:Disease Models, Animal; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation; D018805:Sepsis / Q000209:etiology; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology*