Interferon-alpha and interferon-gamma production capacity of idiopathic isolated optic neuritis patients.
Interferon-alpha and interferon-gamma production by idiopathic isolated optic neuritis (ON) patients was studied. The production capacity was compared with that in two control groups: patients with iritis and healthy control subjects. A sensitive and reliable interferon bioassay was applied for interferon level measurements. Statistically significant differences were not found between patients and control groups in either interferon-alpha production or interferon-gamma production.
D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007370:Interferon Type I / Q000276:immunology / Q000378:metabolism*; D007371:Interferon-gamma / Q000276:immunology / Q000378:metabolism*; D008297:Male; D009902:Optic Neuritis / Q000276:immunology / Q000378:metabolism*
D006680:HLA Antigens; D007370:Interferon Type I; D007371:Interferon-gamma