[Changes in the occurrence of cytogenetic effects after mutagenic exposure in vivo].
Cytogenetic effects after i. v. administration of thiophosphamide were investigated in rabbit lymphocytes. It was observed, that the rate of chromosome aberrations and SCE increased within a matter of first 6 hours.
D000818:Animals; D002869:Chromosome Aberrations / Q000187:drug effects*; D003434:Crossing Over, Genetic / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008214:Lymphocytes / Q000648:ultrastructure; D009153:Mutagens; D011817:Rabbits; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D013852:Thiotepa / Q000633:toxicity*; D013997:Time Factors
D009153:Mutagens; D013852:Thiotepa
Dinamika izmeneniia chastot tsitogeneticheskikh éffektov posle mutagennogo vozdeĭstviia in vivo.