[Carcinogenic effects of combined exposure to 241Am and gamma-radiation].
In experiments on Wistar rats a study was made of the carcinogenic effects of the combined exposure to 241Am administered intraperitoneally (6.7 to 229.4 kBq/kg body weight) and external gamma-radiation (137Cs, 175 cGy). The occurrence of osteosarcoma, leucosis, skin and mammary tumors increased in the exposed animals. The combined irradiation produced an additive carcinogenic effect.
D000576:Americium / Q000008:administration & dosage; D000818:Animals; D002588:Cesium Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D007274:Injections, Intraperitoneal; D007953:Leukemia, Radiation-Induced / Q000209:etiology / Q000401:mortality; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000401:mortality; D051381:Rats; D011919:Rats, Inbred Strains; D012062:Relative Biological Effectiveness; D012878:Skin Neoplasms / Q000209:etiology / Q000401:mortality; D014916:Whole-Body Irradiation
D002588:Cesium Radioisotopes; D000576:Americium
Opukholevye éffekty kombinirovannogo deĭstviia 241Am i gamma-izlucheniia.