[Status of the sympathetic-adrenal system in the initial and early periods of closed craniocerebral injuries in children].
The authors studied the interaction between the sympathoadrenal system, hemodynamics and respiration in the initial and early periods of closed craniocerebral injury in children, taking into account specific features of the clinical course. As regards the ratio between irritation and inhibition symptoms, three variants of the course of the initial period were elicited, namely; 1) a "smooth course", 2) one with psychomotor excitation and 3) one with "dissociation" of emotional and motor activity. Statistically significant changes in catecholamine metabolism characteristic of the initial and early periods as well as those of every variant of the course were established. The role of vascular insufficiency and of a decreased respiration rate contributing to a drop in the saturation of the arterial blood with oxygen was specified. Corrective impact of some drugs on different links of the changes observed were studied and their optimal combinations were tried.
D000293:Adolescent; D000313:Adrenal Medulla / Q000503:physiopathology*; D001924:Brain Concussion / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004295:Dihydroxyphenylalanine / Q000652:urine; D004837:Epinephrine / Q000032:analysis; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000652:urine; D010100:Oxygen / Q000097:blood; D012119:Respiration; D013564:Sympathetic Nervous System / Q000503:physiopathology*
D004295:Dihydroxyphenylalanine; D010100:Oxygen; D009638:Norepinephrine; D004837:Epinephrine
Sostoianie simpatiko-adrenalovoĭ sistemy v nachal'nom i rannem periodakh zakrytoĭ cherepno-mozgovoĭ travmy u deteĭ.