[Relaxing effect of nicergoline on the female urethra in peripheral neurogenic vesicosphincter dysfunctions].
The authors study the effect of Nicergoline (alpha 1-blocker) on the urethral profile of 13 women with a peripheral type of neurological bladder. With regard to the 3 parameters adopted (maximum urethral pressure, continence zone and continence area), they found decrease of 13%, 8% and 20% respectively.
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D004873:Ergolines / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009126:Muscle Relaxation / Q000187:drug effects; D009530:Nicergoline / Q000494:pharmacology* / Q000627:therapeutic use; D013997:Time Factors; D014521:Urethra / Q000187:drug effects*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*
D004873:Ergolines; D009530:Nicergoline
Effet relaxateur sur l'urètre féminin de la nicergoline dans les dysfonctions vésico-sphinctériennes neurogènes périphériques.