The motile and tactic behaviour of Pseudomonas aeruginosa in anaerobic environments.
ATP generated by the anaerobic metabolism of L-arginine in Pseudomonas aeruginosa was used to maintain the membrane potential. Although both the ATP concentration and membrane potential were lower than in aerobically incubated bacteria, motility and chemotaxis were almost normal. Venturicidin stopped anaerobic motility by abolishing the membrane potential. The addition of venturicidin to aerobic bacteria caused an increase in the membrane potential, but a decrease in internal ATP concentration, resulting in bacteria which were motile but non-chemotactic. The membrane potential was the only requirement for continued motility but ATP was required in addition for chemotaxis.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000693:Anaerobiosis; D001120:Arginine / Q000378:metabolism / Q000494:pharmacology; D002633:Chemotaxis / Q000187:drug effects; D008564:Membrane Potentials / Q000187:drug effects; D009068:Movement / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000502:physiology*; D012694:Serine / Q000494:pharmacology; D014698:Venturicidins / Q000494:pharmacology
D014698:Venturicidins; D012694:Serine; D000255:Adenosine Triphosphate; D001120:Arginine