Osmoregulation of alkaline phosphatase synthesis in Escherichia coli K-12.
Alkaline phosphatase, the phoA product, is synthesized constitutively in phoR mutants. This constitutive synthesis, which is independent of phosphate control, varies with changes in the osmolarity of the growth medium; phoA expression increases with increasing osmolarity. Maximum expression of the osmoregulated genes phoA, ompC, and ompF was achieved by osmotic manipulation of minimal medium; complex media repressed their expression.
D000469:Alkaline Phosphatase / Q000235:genetics*; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics; D005796:Genes; D005798:Genes, Bacterial; D007700:Kinetics; D009154:Mutation; D009876:Operon; D014882:Water-Electrolyte Balance; D001616:beta-Galactosidase / Q000235:genetics
D000469:Alkaline Phosphatase; D001616:beta-Galactosidase