Initial sensitivity of rat inbred strains to acute alcohol.
The ethanol sensitivity of eight inbred strains and one heterogeneous stock of rats has been determined by the assessment of "sleep time" and blood alcohol levels upon awakening. In addition, levels of liver alcohol and aldehyde dehydrogenases and phenobarbital-inducible aldehyde dehydrogenase were determined. These data are presented as baseline values for correlation and selective breeding studies using the heterogeneous rats.
D000437:Alcoholism / Q000235:genetics*; D000444:Aldehyde Dehydrogenase / Q000235:genetics; D000818:Animals; D003433:Crosses, Genetic; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D008657:Metabolic Clearance Rate; D051381:Rats; D011919:Rats, Inbred Strains; D012894:Sleep Stages / Q000187:drug effects
D000431:Ethanol; D000444:Aldehyde Dehydrogenase