[Ep 1 and Ep 2--2 new monoclonal antibodies against human T-lymphocytes: candidates for therapeutic use?].
The cytotoxic monoclonal antibodies Ep 1 and Ep 2 are directed against human T-cells recognizing structures different from the antigens Leu 1 to 5. Our results, so far, encourage the investigation of these antibodies as substitution of ATG in transplantation medicine.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000302:isolation & purification* / Q000627:therapeutic use; D000918:Antibody Specificity; D002460:Cell Line; D003510:Cyclohexanes / Q000302:isolation & purification* / Q000627:therapeutic use; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D016030:Kidney Transplantation; D007938:Leukemia; D051379:Mice; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D003510:Cyclohexanes; C041379:dicyclohexyl 2,3-epoxysuccinate
Ep 1 und Ep 2--zwei neue monoklonale Antikörper gegen humane T-Lymphozyten: Kandidaten für eine therapeutische Anwendung?