[A case of bullous dermatosis at the end of pregnancy transmitted to the newborn: herpes gestationis].
The authors report a case of bullous dermatosis developing at 38 weeks of amenorrhoea in a para II. The newborn infant developed a skin rash 3 days after birth. Direct immunofluorescent study of skin biopsies showed the presence of a very small amount of IgG and a very large amount of complement fixed to the basal membrane. Tests for the presence of Herpes gestationis factor in maternal and child blood by immunofluorescence to anti-complement were negative. Tests for anti-epidermal antibodies by indirect immunofluorescence in the serum were also negative, for both anti-basal membrane antibodies as well as anti-intercellular substance antibodies.
D000328:Adult; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007231:Infant, Newborn; D008297:Male; D006559:Pemphigoid Gestationis / Q000175:diagnosis / Q000276:immunology / Q000635:transmission*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000276:immunology / Q000635:transmission*; D012872:Skin Diseases, Vesiculobullous / Q000635:transmission*
D007074:Immunoglobulin G; D003165:Complement System Proteins
Un cas de dermatose bulleuse de fin de grossesse "transmise" au nouveau-né: herpes gestationis.