HLA antigens A, B, C and DR in hay-fever families of similar environmental conditions.
Investigation of 98 members (healthy and affected) belonging to 17 hay-fever families, for clinical picture, total and specific IgE and HLA A, B, C and DR is presented. There was no significant correlation between hay-fever, total or specific IgE and a certain HLA antigen or haplotype. There was, however, an association between hay-fever and same haplotype within 4 of the 17 families.
D000328:Adult; D002648:Child; D006680:HLA Antigens / Q000032:analysis*; D006239:Haplotypes; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007557:Israel; D010375:Pedigree; D006109:Poaceae; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology / Q000235:genetics* / Q000276:immunology
D006680:HLA Antigens; D007073:Immunoglobulin E