[Apolipoproteins: valuable indicators of atherogenicity in patients with coronary disease and normal blood lipids].
The lipid, lipoprotein and apolipoprotein B, A-I and A-II fractions in 20 young patients, (mean age 34.4 years) with myocardial infarction were compared with the results of a control group of 20 healthy men (mean age 35.8 years). The apolipoproteins B and A-I distinguished the myocardial infarction from the control patients. The patient group (who had slightly lower total and HDL cholesterol levels) had significantly higher apo B and lower A-I fractions than the controls. There was no significant difference in apo A-II fractions between the two groups. The measurement of the apo B and A-I fractions would appear to improve the lipid diagnosis by distinguishing the patients predisposed to atherosclerosis due to disorders of fat metabolism who may not be detected by less detailed lipid studies.
D000328:Adult; D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins / Q000097:blood*; D001055:Apolipoproteins B; D001161:Arteriosclerosis / Q000517:prevention & control; D003327:Coronary Disease / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*; D012306:Risk
D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins; D001055:Apolipoproteins B; D008055:Lipids
Les apolipoprotéines: indicateurs précieux de l'athérogénicité chez les malades souffrant d'affection coronarienne avec lipémie normale.