[Nuclear mutants of Saccharomyces cerevisiae K2 yeasts with decreased killer activity].
Recessive mutations in two chromosomal unlinked genes kir1 and kir2 of Saccharomyces cerevisiae K2 result in weak killer activity or in complete loss of killer capacity. Kir1 is located on chromosome 7 and is linked to ade7 and ski6. The kir1 and kir2 mutants reveal no alteration of cell membrane. They normally excrete acid phosphatase and have a normal level of mating and sporulation. The analysis of the plasmid nucleic acid in two strains containing the mutant alleles kir1-12 and kir2-23 shows the increased content of L double-stranded DNA, the content of M double-stranded RNA being increased.
D000898:Antibiosis; D005038:Ethylnitrosourea / Q000494:pharmacology; D005800:Genes, Fungal / Q000187:drug effects; D005816:Genetic Complementation Test; D009154:Mutation; D010641:Phenotype; D010957:Plasmids / Q000187:drug effects; D012330:RNA, Double-Stranded / Q000235:genetics; D012331:RNA, Fungal / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics*
D012330:RNA, Double-Stranded; D012331:RNA, Fungal; D005038:Ethylnitrosourea
Iadernye mutanty drozhzheĭ Saccharomyces cerevisiae K2 s ponizhennoĭ ubivaiushcheĭ aktivnost'iu.