[Genetic analysis of stomach cancer and precancerous states].
This report is devoted to the genetic study of stomach cancer within the limits of classic and multiple models. Also, analysis of phenotypic and genetic correlations in the system of stomach cancer--pre-cancer and that of the association of this disease with genetic markers were conducted. The reliable dependence of the development of stomach cancer on genetic factors is shown and its genetic stipulation with individual forms of ulcer disease and gastritic is determined. The problem of their genetic heterogeneity has been discussed based on these findings. The values of recurrence risk of the development of stomach cancer in population of Moscow and those of the expressivity of connection of ulcer disease forms and stomach cancer with genetic variants of the ABO and Rhesus systems were obtained.
D000017:ABO Blood-Group System / Q000235:genetics; D005260:Female; D005756:Gastritis / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D008297:Male; D009031:Moscow; D010437:Peptic Ulcer / Q000453:epidemiology / Q000235:genetics; D010641:Phenotype; D011230:Precancerous Conditions / Q000453:epidemiology / Q000235:genetics*; D012204:Rh-Hr Blood-Group System / Q000235:genetics; D012306:Risk; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000235:genetics*
D000017:ABO Blood-Group System; D005819:Genetic Markers; D012204:Rh-Hr Blood-Group System
Geneticheskiĭ analiz raka zheludka i nekotorykh predrakovykh sostoianiĭ.