Crotamiton lotion in pruritus.
The authors studied the antipruritic effects of 10% crotamiton lotion in 31 patients with bilaterally symmetrical pruritic dermatoses. In this double-blind, paired-comparison clinical trial, there was no significant difference in relief of pruritus between the crotamiton lotion and its vehicle. The study does not confirm the results of previous uncontrolled studies indicating that crotamiton has an antipruritic effect.
D000287:Administration, Topical; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D011537:Pruritus / Q000188:drug therapy*; D014052:Toluidines / Q000008:administration & dosage / Q000627:therapeutic use*
D014052:Toluidines; C005553:crotamiton