[Morphometric and cytochemical characteristics of the hepatocytes isolated from the liver of rats after a single exposure to 4,dimethylaminoazobenzene].
Hepatocytes have been characterized that were isolated with sodium perchlorate from the livers of rats both intact and given a single injection of a carcinogen--4-dimethylaminoazobenzene. A decreased number of big hepatocytes (600-900 mkm2) and the appearance of small hepatocytes (75-120 mkm2) were observed 7 days after the carcinogen injection. An excessive accumulation of glycogen was shown in certain hepatocytes. By the 30th day the picture was nearly normal.
D000818:Animals; D002469:Cell Separation; D006651:Histocytochemistry; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism; D051381:Rats; D013997:Time Factors; D004124:p-Dimethylaminoazobenzene / Q000494:pharmacology*
D008112:Liver Glycogen; D004124:p-Dimethylaminoazobenzene
Morfometricheskaia i tsitokhimicheskaia kharakteristika gepatotsitov, izolirovannykh iz pecheni krys posle odnokratnogo vozdeĭstviia 4,dimetilaminoazobenzola.