Interference in the radioallergosorbent test by antibody light chains in rabbit urine.
Immunological techniques have been used to identify and quantitate rabbit antibody light chains in the urine of rabbits. The influence of these light chains on the radioallergosorbent test (RAST) used for the diagnosis of laboratory animal allergy to rabbit urinary protein allergens is described. The presence of IgG antibody specific for rabbit derived antigens in human serum has been confirmed.
D000818:Animals; D002846:Chromatography, Affinity; D006801:Humans; D005779:Immunodiffusion / Q000379:methods; D007122:Immunoelectrophoresis / Q000379:methods; D007073:Immunoglobulin E / Q000032:analysis*; D007147:Immunoglobulin Light Chains / Q000652:urine*; D011817:Rabbits; D011852:Radioallergosorbent Test / Q000379:methods
D007147:Immunoglobulin Light Chains; D007073:Immunoglobulin E