[Heterotopic ossification in the skeletal muscle metastases of advanced stomach cancer].
The formation of heterotopic bone tissue in carcinomas of the gastrointestinal tract and/or their metastases is extremely rare. In a 74-year-old female with gastric adenocarcinoma, we observed extensive bone formation within metastases in the skeletal muscles. There are only 7 other cases of heterotopic bone formation in gastric cancer reported in the world literature. We suggest that heterotopic ossification in primary cancers and/or their metastases is probably the result of metaplasia of stromal fibroblasts into osteoblasts.
D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009132:Muscles / Q000473:pathology; D009362:Neoplasm Metastasis; D009999:Ossification, Heterotopic / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000556:secondary*; D013274:Stomach Neoplasms / Q000473:pathology