Initial experience with indium-111 autologous leucocyte imaging in patients with acute pancreatitis.
Indium-111 labelled autologous leucocyte imaging was used to assess severity in 13 patients with acute pancreatitis. All three patients with severe disease as judged by a prognostic factor grading system had a positive result on imaging. A fourth patient with mild disease as judged by prognostic factors had a positive imaging result and 14 days later developed a pseudocyst. There were no false positive or false negative scans. Evidence from three patients suggested that a positive 111In-leucocyte imaging result implies substantial fat necrosis. In this study imaging was as accurate as prognostic factor grading. The technique may be a useful method of separating mild from severe acute pancreatitis.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006912:Hydroxyquinolines; D007204:Indium; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011379:Prognosis; D011446:Prospective Studies; D011868:Radioisotopes; D011877:Radionuclide Imaging; D014463:Ultrasonography
D006912:Hydroxyquinolines; D009942:Organometallic Compounds; D011868:Radioisotopes; D007204:Indium; C032950:indium oxine; D015125:Oxyquinoline