Acute renal failure with hypocreatininemia in Guillain-Barré syndrome.
A 68-year-old woman with Guillain-Barré syndrome had profoundly depressed serum creatinine concentration and 24-hour urinary creatinine excretion despite maintenance of her weight by hyperalimentation. Because of hypocreatininemia, the development of aminoglycoside-induced acute renal failure was initially missed. A retrospective study of seven patients with Guillain-Barré syndrome who were treated with hyperalimentation to maintain nutritional status showed a significant decrease in serum creatinine concentration but no significant decline in weight or blood urea nitrogen level. Because the serum creatinine is decreased in patients with Guillain-Barré syndrome, caution must be exercised in using serum creatinine determination as an estimate of glomerular filtration rate.
D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D001806:Blood Urea Nitrogen; D001835:Body Weight; D003404:Creatinine / Q000097:blood* / Q000652:urine; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D009460:Neurologic Examination; D011129:Polyradiculoneuropathy / Q000150:complications* / Q000175:diagnosis / Q000178:diet therapy; D012189:Retrospective Studies
D003404:Creatinine