[Comparative study of the reactogenicity and immunogenicity of various doses of a chemical polysaccharide meningococcal vaccine administered by syringe and jet injector].
The article presents the results obtained in the comparative study of the reactogenicity and immunogenic potency of different doses of chemical polysaccharide meningococcal vaccine, type A, introduced with a syringe and a jet-injector. The preparation has been shown to possess low reactogenicity, high immunogenic potency and to produce a sufficiently pronounced intensity of postvaccinal immunity. The preparation is recommended for wide use in immunization of adults in a dose of 75 micrograms.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D001831:Body Temperature / Q000187:drug effects; D004306:Dose-Response Relationship, Immunologic; D004341:Drug Evaluation; D006801:Humans; D007273:Injections, Intramuscular; D007277:Injections, Jet; D009345:Neisseria meningitidis / Q000276:immunology*; D010919:Placebos; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013997:Time Factors
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D010919:Placebos; D011135:Polysaccharides, Bacterial
Sravnitel'noe izuchenie reaktogennosti i immunogennosti razlichnykh doz khimicheskoĭ polisakharidnoĭ meningokokkovoĭ vaktsiny pri shpritsevom i struĭnom metodakh ee vvedeniia.