A histopathological study on the etiology of duodenal diverticulum related to the fusion of the pancreatic anlage.
In 18 of 27 cases a duodenal diverticulum, which usually occurs at "weak" spots in the bowel wall, penetrated the pancreas. Of these, 14 cases (77.8%) extended along the embryological fusion line of the ventral and dorsal components, which is considered to be the so-called "locus minoris resistantiae." In four cases the diverticulum penetrating the ventral pancreas was in close approximation to the locus minoris resistantiae.
D000368:Aged; D004240:Diverticulum / Q000473:pathology*; D004378:Duodenal Diseases / Q000473:pathology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology*