Antinuclear antibodies in diagnosis and management.
Antinuclear antibodies are known to be present in a variety of autoimmune diseases, and they appear to play a primary role in the pathogenesis of a subgroup of "ANA diseases." It has been shown that each presents a distinct ANA profile, characterized by the presence and titer of certain antibodies and the absence of others. These profiles are of practical value in diagnosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003882:Dermatomyositis / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000276:immunology; D012595:Scleroderma, Systemic / Q000276:immunology; D012737:Sex Factors; D012859:Sjogren's Syndrome / Q000276:immunology
D000974:Antibodies, Antinuclear