Failure to detect nucleic acid homology between some non-A, non-B viruses and hepatitis B virus DNA.
Some studies suggest that there is antigenic and nucleic acid homology of one type of non-A, non-B hepatitis virus with hepatitis B viral (HBV) proteins and DNA. Using molecular hybridization under high and low stringency conditions with high specific activity 32P-HBV DNA as a probe, serum and liver samples from patients and nonhuman primates infected with non-A, non-B hepatitis were examined. Our results provide no evidence of significant homology between the DNA extracted from serum and liver of patients and nonhuman primates infected with one type of non-A, non-B hepatitis and HBV DNA.
D000818:Animals; D001483:Base Sequence; D002143:Callitrichinae; D004279:DNA, Viral / Q000032:analysis / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics*; D006526:Hepatitis C / Q000382:microbiology; D006518:Hepatitis Viruses / Q000235:genetics*; D006801:Humans; D008099:Liver / Q000032:analysis / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D002679:Pan troglodytes
D004279:DNA, Viral