[Long-term drug therapy in inflammatory rheumatic diseases using chronic polyarthritis as an example. 2. Basic principles of long-term drug therapy: choice of optimal therapeutic agents].
The article reviews the principles of the long-term drug therapy of rheumatoid arthritis. A nomogram is presented which allows selection of adequate antiphlogistic and long-term drugs according to activity and progression of the disease. Steroids, non-steroidal antiphlogistics, gold, D-penicillamine and azathioprine are described in the order of their application during treatment of a severe polyarticular flare-up. Some of the drug regimens are relevant also to diseases other than rheumatoid arthritis, but drug therapy reflects only a single aspect in the treatment of these diseases and has to be applied together with non-pharmacologic methods (surgery, physical therapy, functional therapy, psychology etc.).
D000962:Antimalarials / Q000008:administration & dosage / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006046:Gold / Q000627:therapeutic use; D006052:Gold Sodium Thiomalate / Q000008:administration & dosage; D006801:Humans; D008134:Long-Term Care; D010396:Penicillamine / Q000008:administration & dosage / Q000627:therapeutic use
D000962:Antimalarials; D006052:Gold Sodium Thiomalate; D006046:Gold; D010396:Penicillamine; D001379:Azathioprine
Medikamentöse Langzeittherapie bei entzündlich-rheumatischen Krankheiten am Beispiel der chronischen Polyarthritis. Teil 2: Grundpfeiler der medikamentösen Langzeittherapie: Auswahl des optimalen Basistherapeutikums.