Antibody-dependent cellular cytotoxicity in chronic human Chagas disease.
Antibody-dependent cellular cytotoxicity mediated by granulocytes (ADGC) or lymphocytes (ADLC) was assessed in 23 patients with chronic Chagas disease. The results of ADGC against T. cruzi were normal. ADLC against chicken erythrocytes was significantly reduced in patients as compared with normal controls. Possible causes of this abnormality were investigated.
D000920:Antibody-Dependent Cell Cytotoxicity; D000961:Antilymphocyte Serum / Q000032:analysis; D014355:Chagas Disease / Q000276:immunology*; D002908:Chronic Disease; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology
D000961:Antilymphocyte Serum