[Role of catecholamine neurons in the reticular lateral nuclei in regulating sensitivity to pain during exposure to reflex stimuli].
Experiments were made on rats in which the effects of catecholaminergic neuronal systems of lateral reticular A-1 nuclei were eliminated with 6-OHDA. The latency of pain reactions tested by the hot-plate and tail-flick tests remained unchanged after operation. After auricular electric acupuncture the rats manifested no changes in the above reactions as compared with the initial level, which evidences that A-1 nuclei play an important role in the mechanisms of analgesia under consideration. Stimulation of the small pelvis organs (SSPO) entailed a short-term and significant inhibition of the analgetic effect as regards the control which also points to the involvement of A-1 nuclei into activation of antinociceptive processes. Besides, during SSPO, there was a significant elevation of the response measured by the tail-flick test as compared to the initial level of the pain reaction.
D015670:Acupuncture Therapy; D000698:Analgesia; D000818:Animals; D005260:Female; D006892:Hydroxydopamines / Q000494:pharmacology; D008297:Male; D016627:Oxidopamine; D010146:Pain / Q000503:physiopathology*; D051381:Rats; D012018:Reflex / Q000502:physiology*; D012154:Reticular Formation / Q000187:drug effects / Q000502:physiology*
D006892:Hydroxydopamines; D016627:Oxidopamine
Rol' katekholaminovykh neĭronov retikuliarnykh bokovykh iader v reguliatsii bolevoĭ chuvstvitel'nosti pri deĭstvii nekotorykh vidov reflektornykh razdrazhiteleĭ.