Prophylactic antibiotic wound irrigation in gastric, biliary, and colonic surgery.
Intermittent intraoperative antibiotic irrigation from the beginning of an operative procedure to its completion is a valuable supplement to hospital and operating room cleanliness and to good surgical technique. A prospective, randomized, double-blind study of 200 patients undergoing clean-contaminated operations on the gastrointestinal tract demonstrated a marked reduction in the incidence of postoperative wound infection and absolute prevention of postoperative peritonitis.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001662:Biliary Tract Surgical Procedures; D002512:Cephalothin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D003106:Colon / Q000601:surgery*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007612:Kanamycin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D013270:Stomach / Q000601:surgery*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D007507:Therapeutic Irrigation
D000900:Anti-Bacterial Agents; D007612:Kanamycin; D002512:Cephalothin