Competition between isogenic mutS and mut+ populations of Escherichia coli K12 in continuously growing cultures.
Previous studies have shown that the mutT, mutH and mutL mutators of Escherichia coli have a marked advantage in competition growth with otherwise coisogenic wild-type strains. As shown in this paper the same is true for the mutS mismatch mutator. In three experiments mutS could outgrow the wild-type and had higher fitness values.
D005075:Biological Evolution; D002455:Cell Division; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D005798:Genes, Bacterial; D009154:Mutation