Uptake of methionine sulfoximine by some N2 fixing bacteria, and its effect on ammonium transport.
The N2 fixing bacteria Klebsiella pneumoniae, Azospirillum brasilense, Rhodopseudomonas sphaeroides and Rhodospirillum rubrum, but not Azotobacter vinelandii accumulate the glutamine analogue methionine sulfoximine in the cell. In the accumulating cells methionine sulfoximine inhibits ammonium transport. Accumulation and inhibition are prevented by glutamine.
D000641:Ammonia / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001692:Biological Transport; D002250:Carbon Radioisotopes; D007700:Kinetics; D007711:Klebsiella pneumoniae / Q000378:metabolism; D008717:Methionine Sulfoximine / Q000378:metabolism*; D009586:Nitrogen Fixation; D012242:Rhodobacter sphaeroides / Q000378:metabolism; D012247:Rhodospirillum rubrum / Q000378:metabolism; D013045:Species Specificity
D002250:Carbon Radioisotopes; D008717:Methionine Sulfoximine; D000641:Ammonia