Effects of antioxidants on the TBA reaction of various rat liver homogenates.
The TBA reaction of physiologically normal (young and aged) rat liver homogenate appears to be catalyzed mainly by nonheme iron which is sensitive to EDTA, whereas some iron species which are not affected by EDTA seem to be functioning as catalysts in the TBA reaction of drug-intoxicated (CCl4, HCB) liver homogenates.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism; D004492:Edetic Acid / Q000494:pharmacology; D006581:Hexachlorobenzene / Q000506:poisoning; D007501:Iron / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013858:Thiobarbiturates
D000975:Antioxidants; D013858:Thiobarbiturates; D002084:Butylated Hydroxytoluene; D006581:Hexachlorobenzene; D004492:Edetic Acid; D007501:Iron