Feline miliary eczema: megestrol acetate does not suppress immune responses.
Megestrol acetate was found to have no influence on immunological skin and corneal reactivity nor on antibody responses in guinea pigs. Its curative effect in feline miliary eczema is probably not, therefore, the result of interference with the immune response.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D002371:Cat Diseases / Q000188:drug therapy; D002415:Cats; D003315:Cornea / Q000276:immunology; D003872:Dermatitis / Q000188:drug therapy / Q000662:veterinary; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D005260:Female; D005620:Freund's Adjuvant / Q000276:immunology; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D008535:Megestrol / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D019290:Megestrol Acetate; D009169:Mycobacterium tuberculosis / Q000276:immunology; D010047:Ovalbumin / Q000276:immunology; D012867:Skin / Q000276:immunology
D010047:Ovalbumin; D005620:Freund's Adjuvant; D008535:Megestrol; D019290:Megestrol Acetate