[Morphofunctional analysis of the chief (peptic) glandulocytes in the stomach of hibernating rodents].
Ultrastructure of the chief gastric gland cells has been studied in the ground squirrel (Cytellus erythrogenys Brandt) at various seasons of the year. When the ground squirrel is in the active state, the cells studied do not differ from those in other animals. During winter hibernation, their activity is inhibited. During first days of awakening, the activity of the chief cells increases; the protein-synthesizing apparatus, the Golgi complex become activated, secreating granules accumulate. At the same time, the greatest number of the destroing cellular elements and discharge of the residual bodies out of the activizing cells are observed. Restoration of the normal structure in the chief cells is completed by the end of the second week. No signs demonstrating transformation of additional cells into the chief ones are revealed. Non-differentiated cells in the ground squirrel fundal glands are widely distributed along the whole length of the glandular cervix and occur even in the upper parts of its body.
D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D006605:Hibernation; D008854:Microscopy, Electron; D010434:Pepsin A / Q000378:metabolism*; D012377:Rodentia / Q000502:physiology*; D012621:Seasons
D010434:Pepsin A
Morfofunktsional'nyĭ analiz glavnykh (pepticheskikh) glandulotsitov zheludka zimnespiashchego gryzuna.