[Diagnostic value of the human basophil degranulation test in schistosomiasis].
The human basophil degranulation test (HBDT) was applied to the diagnosis of schistosomiasis. In 120 cases confirmed by parasitological examination, the test was shown to be extremely sensitive (90% clearly positive responses) and specific. The total immunoglobulin E levels were higher in infested subjects (average value: 2,000 IU/ml) compared to an average of 500 IU/ml in control subjects. However, wide individual variations were observed and other parasitoses can also produce considerable increases. The measurement of specific IgE showed a clear response with high positive levels in patients with bilharziasis whereas the response was always negative in the controls.
D000328:Adult; D000947:Antigens, Helminth / Q000032:analysis; D001491:Basophils / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007158:Immunologic Techniques; D012552:Schistosomiasis / Q000175:diagnosis* / Q000276:immunology; D012698:Serologic Tests
D000947:Antigens, Helminth; D007073:Immunoglobulin E
Valeur diagnostique du test de dégranulation des basophiles humains dans les schistosomoses.