Diameter changes in rabbit aorta during fixation at physiological pressure.
The rabbit aorta distends considerably during glutaraldehyde infusion at 100 mm Hg, the distension at the beginning being both fastest and greatest. Over a 2-h period the degree of distension approached a maximum value which was clearly above the in vivo distension. Intimal folds were largely flattened, especially in experiments with the largest distension, but were clear among those with the least distension.
D000818:Animals; D001011:Aorta / Q000473:pathology*; D001012:Aorta, Abdominal; D001794:Blood Pressure; D005260:Female; D005976:Glutaral / Q000008:administration & dosage; D007261:Infusions, Intra-Arterial; D008297:Male; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D012965:Sodium Chloride / Q000008:administration & dosage
D012965:Sodium Chloride; D005976:Glutaral