Topical antibiotic therapy of acne: laboratory investigation of vehicles, various antibiotics, and stability characteristics.
A new vehicle preparation has proved effective in enhancing the penetration of antibiotics. The vehicle seems to maintain stability of the incorporated antibiotic.
D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D001682:Biological Availability; D004339:Drug Compounding; D004355:Drug Stability; D004917:Erythromycin / Q000378:metabolism; D006801:Humans; D012867:Skin / Q000378:metabolism
D000900:Anti-Bacterial Agents; D004917:Erythromycin