Immunohistochemical identification of Aspergillus fumigatus in farmer's lung.
Fragments of fungi in a granuloma were demonstrated in lung biopsy specimens of two patients with farmer's lung by using an avidin-biotin-complex method with non-conjugated rabbit antiserum to Aspergillus fumigatus. Our findings suggest that the type IV or cell-mediated immunity at least partly explains the pathogenesis of farmer's lung.
D000946:Antigens, Fungal / Q000302:isolation & purification; D001232:Aspergillus fumigatus / Q000276:immunology / Q000302:isolation & purification*; D005203:Farmer's Lung / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007120:Immunochemistry
D000946:Antigens, Fungal