[Histological and histochemical changes in the hip joint capsule in arthrosis in elderly patients. Study of 57 surgical and 28 autopsy specimens].
The authors make a histological and histochemical study of the articular capsule, in arthrosis and senescence. They basically observe fibrosis and a decrease of the elastic tissue in aged subjects and an increase in the level of acid mucopolysaccharides of the interstitial in more than 50% of arthrosics. There are also micro-deposits of amyloid substances in more than 25% of subjects over eighty. This study provides an argument in favor of the opinion of Lagier according to which arthrosis should not be considered the same as a manifestation of senescence. On the other hand, it appears that microscopic amyloidose of the articular capsule of the old patient is not related to arthrosic phenomena but rather constitutes a local manifestation of senescence.
D000328:Adult; D000368:Aged; D000375:Aging; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006025:Glycosaminoglycans; D006621:Hip Joint / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D007592:Joint Diseases / Q000378:metabolism / Q000473:pathology*; D008297:Male
D006025:Glycosaminoglycans
Altérations histologique et histochimique de la capsule articulaire dans l'arthrose et chez les sujets séniles. Etude basée sur 57 prélèvements per-opératoires et 28 prélèvements d'autopsie.