[Value of the histoenzymologic characterization of esterases in normal and pathologic rectal mucosa in children. Preliminary results of 30 cases].
The presence of cholinergic nerve fibers is studied in 30 suction rectal biopsy specimens from 5 days to 7 years old children. An increase in numbers and size of cholinergic fibers in the lamina propria and muscularis mucosae and absence of submucosa ganglion cells are related to 7 Hirschsprung's diseases. In the neonates acetylcholinesterase activity may not be strong enough to stain cholinergic fibers and makes the diagnosis more difficult.
D002648:Child; D002675:Child, Preschool; D002799:Cholinergic Fibers / Q000032:analysis; D004796:Clinical Enzyme Tests; D004950:Esterases / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007413:Intestinal Mucosa / Q000201:enzymology*; D008531:Megacolon / Q000175:diagnosis*; D012007:Rectum / Q000201:enzymology*
D004950:Esterases
Intérêt de la caractérisation histoenzymologique des estérases dans la muqueuse rectale normale et pathologique chez l'enfant. Résultats préliminaires sur 30 cas.