title: On inactivation of bacteriophage lambda by hydroxylamine.
abstract: Hydroxylamine is a mutagen which is much more active on single-stranded DNA than on double-stranded DNA. It is shown here that the cohesive ends of lambda DNA, with 10 cytidine residues, constitute a hydroxylamine target roughly equal in magnitude to the entire duplex part of the molecule, which contains ca.  25 000 cytidine residues.
mesh_terms: D010582:Bacteriophage lambda / Q000187:drug effects* / Q000235:genetics; D001482:Base Composition; D003562:Cytidine / Q000032:analysis / Q000235:genetics; D004277:DNA, Single-Stranded / Q000032:analysis / Q000235:genetics; D004279:DNA, Viral / Q000032:analysis / Q000235:genetics*; D006898:Hydroxylamines / Q000494:pharmacology*; D009153:Mutagens
chemical_list: D004277:DNA, Single-Stranded; D004279:DNA, Viral; D006898:Hydroxylamines; D009153:Mutagens; D003562:Cytidine