[Possibility of using the indirect fluorescent antibody technic to analyze immunoglobulins in certain neurogenetic diseases].
Results of examining the sera of 11 normal donors and 37 patients with various neutogenetic diseases using, the Coons indirect immunofluorescence technique are presented. The patients' immunoglobulins could be better fixed on nervous tissue components than those of the control donors. This seems likely to be due to both a rise in the content of serum immunoglobulins and accumulation of specific anticerebral antibodies in the patients' blood. It is suggested that in all cases of using indirect immunofluorescence the quantitative determination of immunoglobulins and serum titration should be carried out.
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D004422:Dystonia Musculorum Deformans / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D005621:Friedreich Ataxia / Q000276:immunology; D006527:Hepatolenticular Degeneration / Q000276:immunology; D006801:Humans; D006816:Huntington Disease / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis*; D007585:Jews; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000235:genetics*; D014202:Tremor / Q000235:genetics / Q000276:immunology
D001323:Autoantibodies; D007136:Immunoglobulins
O vozmozhnosti ispol'zovaniia metoda nepriamoi immunofliuorestsentsii dlia analiza immunoglobulinov pri nekotorykh neĭrogeneticheskikh zabolevaniiakh.