[Stimulation of cell division by Ehrlich carcinoma cell surface antibodies].
Some Ehrlich ascites cancer cells of the mouse show nuclear division as a response to cell surface signals. Antibodies to plasma membrane produce a membrane molecular redistribution, but only 25 per 100 proceed to nuclear division. This division is not associated to DNA synthesis, showing that the effect is produced in G0 phase cells originated from G2 phase cells.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000276:immunology*; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology* / Q000648:ultrastructure; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002462:Cell Membrane / Q000276:immunology; D002467:Cell Nucleus / Q000187:drug effects; D003078:Colchicine / Q000494:pharmacology; D003513:Cycloheximide / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003609:Dactinomycin / Q000494:pharmacology; D005260:Female; D007106:Immune Sera / Q000494:pharmacology*; D007213:Indomethacin / Q000494:pharmacology; D007399:Interphase / Q000187:drug effects; D051379:Mice; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology; D009363:Neoplasm Proteins / Q000096:biosynthesis; D012334:RNA, Neoplasm / Q000096:biosynthesis; D011817:Rabbits
D000912:Antibodies, Neoplasm; D004273:DNA, Neoplasm; D007106:Immune Sera; D008937:Mitomycins; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D003609:Dactinomycin; D003571:Cytochalasin B; D016685:Mitomycin; D003513:Cycloheximide; D003078:Colchicine; D007213:Indomethacin
Estimulación de la división celular por anticuerpos contra la superficie de las células del carcinoma de Ehrlich.