Acquisition of K:1-like antigen during terminal sepsis.
This report describes a patient whose own and transfused K:-1 red cell populations became strongly K:1 during a terminal episode of sepsis due to a group D streptococcus organism, Streptococcus faecium. Subsequent in vitro studies using normal K:-1 red cells inoculated with that organism showed that it could render the red cells agglutinable by reagents containing IgG anti-K1. In addition, disrupted S. faecium organisms rendered Jkb-negative red cells agglutinable by those reagents.
D000942:Antigens, Bacterial / Q000276:immunology; D001789:Blood Group Antigens / Q000235:genetics / Q000276:immunology; D013293:Enterococcus faecalis / Q000276:immunology; D006801:Humans; D007626:Kell Blood-Group System / Q000235:genetics / Q000276:immunology; D007667:Kidd Blood-Group System; D008297:Male; D010641:Phenotype; D012772:Shock, Septic / Q000097:blood* / Q000209:etiology / Q000276:immunology; D013290:Streptococcal Infections / Q000097:blood* / Q000150:complications / Q000276:immunology
D000942:Antigens, Bacterial; D001789:Blood Group Antigens; D007626:Kell Blood-Group System; D007667:Kidd Blood-Group System