Properties of an immunogenic fraction from Brucella abortus 45/20.
Hot saline extracts of Brucella abortus strain 45/20 contain up to 4 protein components. Some of these components are shared with other Brucella strains but one appears specific to B. abortus 45/20 or possibly other non-smooth Brucella strains. The extracts are antigenic in guinea-pigs and evoke protective immunity against virulent B. abortus. The rough antigen specific activity appears to be associated with a protein component rather than lipopolysaccharide.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D002003:Brucella abortus / Q000276:immunology*; D055598:Chemical Phenomena; D002621:Chemistry; D006168:Guinea Pigs; D007114:Immunization; D007158:Immunologic Techniques; D011817:Rabbits; D013045:Species Specificity
D000942:Antigens, Bacterial