Comparison of long acting oxytetracycline and parvaquone in immunisation against East Coast fever by infection and treatment.
Two groups of five cattle were immunised with a field isolate of Theileria parva as stabilate and simultaneously treated with long acting oxytetracycline or parvaquone in early clinical disease. The oxytetracycline group suffered a marked fall in leucocyte count and one animal died during immunisation. The parvaquone group suffered a less severe fall in leucocyte count and all survived. The surviving immunised cattle were immune to homologous challenge but susceptible to subsequent challenge with T p lawrencei.
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D016782:Apicomplexa / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D003692:Delayed-Action Preparations; D007114:Immunization / Q000662:veterinary*; D007958:Leukocyte Count / Q000662:veterinary; D007962:Leukocytes / Q000166:cytology; D008297:Male; D009285:Naphthoquinones / Q000627:therapeutic use*; D010118:Oxytetracycline / Q000627:therapeutic use*; D013801:Theileriasis / Q000097:blood / Q000188:drug therapy* / Q000276:immunology
D000981:Antiprotozoal Agents; D003692:Delayed-Action Preparations; D009285:Naphthoquinones; C028032:parvaquone; D010118:Oxytetracycline