A comparison of low dosage trimethoprim/sulfamethoxazole with oxytetracycline in acne vulgaris.
It has been well documented that acne vulgaris usually responds well to long-term systemic tetracycline therapy. However, not all patients respond satisfactorily due to drug intolerance, adverse side effects such as fixed drug eruptions, moniliasis, photosensitivity, and gastric irritation. A double-blind study comparing trimethoprim/sulfamethoxazole with oxytetracycline in the management of acne vulgaris has demonstrated that trimethoprim/sulfamethoxazole is an equally effective and as safe therapeutic agent as oxytetracycline. The results of this study are shown to confirm the works of other authors.
D000152:Acne Vulgaris / Q000188:drug therapy*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D010118:Oxytetracycline / Q000627:therapeutic use*; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*
D004338:Drug Combinations; D014295:Trimethoprim; D013420:Sulfamethoxazole; D010118:Oxytetracycline