Factor VIII/von Willebrand factor has potent lectin activity.
Highly-purified plasma and platelet Factor VIII/von Willebrand Factor had potent lectin activity when measured in a haemagglutination assay. This lectin activity was inhibited by monoclonal and heterologous antibodies to Factor VIII/von Willebrand Factor as well as by hexosamines, mannose and net-positively charged amino acids.
D001779:Blood Coagulation Factors / Q000276:immunology*; D001792:Blood Platelets / Q000502:physiology; D005169:Factor VIII / Q000276:immunology*; D006384:Hemagglutination; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D037102:Lectins; D013917:Thrombin / Q000502:physiology; D014841:von Willebrand Factor / Q000276:immunology*
D001779:Blood Coagulation Factors; D037102:Lectins; D014841:von Willebrand Factor; D005169:Factor VIII; D013917:Thrombin