title: Photon-deficient bone scan lesion as a precursor of active Paget's disease.
abstract: A case is presented in which a Pagetoid lesion was demonstrated as a photon-deficient area (cold spot) on the bone scan. This area changed into a hot spot 3 years after its discovery. Clinical and radiological observations provide evidence that a scintigraphically photon-deficient area may represent a precursor of active Paget's disease.
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D012968:Etidronic Acid; D005260:Female; D006801:Humans; D015609:Organotechnetium Compounds; D010001:Osteitis Deformans / Q000000981:diagnostic imaging*; D011859:Radiography; D011877:Radionuclide Imaging; D013131:Spine / Q000000981:diagnostic imaging; D013667:Technetium
chemical_list: D015609:Organotechnetium Compounds; C019561:technetium Tc 99m etidronate; D013667:Technetium; D012968:Etidronic Acid