Prevalence and pathogenesis of impotence in one hundred uremic men.
In a study of dialysis patients 79% of men complained of sexual dysfunction and 61% erectile impotence following uremia and the onset of regular dialysis therapy. Plasma testosterone levels were significantly higher in patients treated by continuous ambulatory peritoneal dialysis (p = 0.001) but the incidence of sexual dysfunction was not different from patients treated by hemodialysis. Although follicle-stimulating hormone levels were higher (p = 0.001) and penile blood pressure index levels lower (p less than 0.05) in patients with impotence, sexual function was not improved by exogenous testosterone, and vasculogenic impotence was identified in only 6% of patients. These findings suggest that a major component of uremic impotence is unrelated to primary testicular failure or penile vascular insufficiency.
D000328:Adult; D000368:Aged; D007172:Erectile Dysfunction / Q000209:etiology*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006177:Gynecomastia / Q000150:complications; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000098:blood supply; D010530:Peritoneal Dialysis; D011388:Prolactin / Q000097:blood; D006435:Renal Dialysis; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood; D014511:Uremia / Q000150:complications*; D015032:Zinc / Q000097:blood
D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D015032:Zinc