[Comparison of the pharmacokinetic behavior of Turivital, Acesal and Micristin].
The 3 acetylsalicylic acid preparations showed at normal patients at the same elimination phase no significant differences concerning the bioavailability (comparison of the area under the concentration-time-curve). The absorption kinetics of the preparations were different: the time up to the maximum serum concentration was at Turivital with 1,3 +/- 0,7 h and Micristin (2,1 +/- 0,8 h) the shortest, because the resorption delay was at Turivital the smallest. Absorption constant, fictive initial concentration and maximum concentration in serum are nearly the same in all 3 preparations.
D000328:Adult; D001205:Ascorbic Acid / Q000494:pharmacology; D001241:Aspirin / Q000378:metabolism*; D001682:Biological Availability; D002110:Caffeine / Q000378:metabolism; D002245:Carbon Dioxide / Q000032:analysis; D004338:Drug Combinations; D004347:Drug Interactions; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007408:Intestinal Absorption; D007700:Kinetics; D008297:Male; D012459:Salicylates / Q000652:urine; D020156:Salicylic Acid
D004338:Drug Combinations; D012459:Salicylates; D002245:Carbon Dioxide; D002110:Caffeine; D020156:Salicylic Acid; D001205:Ascorbic Acid; D001241:Aspirin
Vergleich des pharmakokinetischen Verhaltens von Turivital, Acesal und Micristin.