title: Regulation of aerobic and anaerobic metabolism in facultative anaerobes: a role for cytochrome a1.
abstract: Despite extensive documentation, the regulatory effects of oxygen on protein synthesis are poorly understood. Oxygen either functions directly or indirectly, through changes in Eh or respiratory activity, or by interacting with a sensor molecule analogous to the lac repressor. Cytochrome a1, hitherto of unknown function in most bacteria, is proposed as the likely sensor.
mesh_terms: D000332:Aerobiosis; D000693:Anaerobiosis; D001421:Bacteria, Anaerobic / Q000235:genetics / Q000378:metabolism*; D003580:Cytochromes / Q000378:metabolism*; D045263:Cytochromes a1; D004798:Enzymes / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism
chemical_list: D003580:Cytochromes; D004798:Enzymes; D045263:Cytochromes a1; D010100:Oxygen