title: Indium-111 oxine-labeled autologous leukocyte scans in the management of colorectal diseases.
abstract: The accuracy and usefulness of indium-111 oxine-labeled autologous leukocyte scans in the management of infectious complications of colon and rectal surgery and of inflammatory diseases of the colon have been studied by review of the records of all patients undergoing such scans at Morristown Memorial Hospital during the first six months such scans were performed there. A total of 20 scans was performed on 18 patients. Twelve scans were performed on 11 patients being treated for diseases of the colon and rectum. Of these 12 scans, one was normal, four demonstrated intra-abdominal abscesses, three demonstrated wound infections (two abdominal, one perineal), one was positive for granulomatous colitis, one for pseudomembranous colitis, one for chronic diverticulitis, and one for enterocutaneous fistula. One allergic reaction to the labeled leukocytes occurred. Comparisons with other corroborative localizing diagnostic tests were made. Subsequent treatment was reviewed. Analysis of these cases indicates that the majority of all scans were performed to evaluate complications of colorectal surgery or inflammatory diseases of the colon and that these scans were highly accurate. In all instances where appropriate, delineation of a lesion in the colorectal cases was followed by corrective treatment.
mesh_terms: D000005:Abdomen; D000038:Abscess / Q000000981:diagnostic imaging; D003092:Colitis / Q000000981:diagnostic imaging*; D003108:Colonic Diseases / Q000601:surgery*; D006801:Humans; D006912:Hydroxyquinolines; D007204:Indium; D007962:Leukocytes / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012002:Rectal Diseases / Q000601:surgery*; D013529:Surgical Wound Dehiscence / Q000000981:diagnostic imaging; D013530:Surgical Wound Infection / Q000000981:diagnostic imaging*
chemical_list: D006912:Hydroxyquinolines; D009942:Organometallic Compounds; D011868:Radioisotopes; D007204:Indium; C032950:indium oxine; D015125:Oxyquinoline