Nutritional factors influencing the results of toxicology experiments in animals.
The purpose of this paper is to present experimental data illustrating the importance of a toxicopathological basis necessary for understanding the role of nutrition on drug toxicity. Nutritional status constitutes an important factor capable of modulating the results of animal experiments in toxicology. Therefore, it is necessary in any toxicity testing to consider the effects of nutrition on drug toxicity and, at the same time, the effect of drug toxicity on the nutritional state of animals.
D000818:Animals; D009202:Cardiomyopathies / Q000517:prevention & control; D002908:Chronic Disease; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D005260:Female; D007674:Kidney Diseases / Q000209:etiology; D008297:Male; D016686:Monocrotaline; D009747:Nutritional Physiological Phenomena; D011763:Pyrrolizidine Alkaloids / Q000506:poisoning; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains; D014116:Toxicology
D004044:Dietary Proteins; D011763:Pyrrolizidine Alkaloids; D016686:Monocrotaline