Mucoid conversion by phages of Pseudomonas aeruginosa strains from patients with cystic fibrosis.
A total of 21 of 22 independent isolates of cystic fibrosis-associated Pseudomonas aeruginosa were found to be lysogenic for DNA-containing, complex capsid viruses. Several of the phages demonstrated the ability to select mucoid cells from populations of nonmucoid bacteria. Conversion to mucoid growth was more frequently achieved when phages were isolated from mucoid as opposed to nonmucoid cystic fibrosis-associated strains.
D000464:Alginates / Q000378:metabolism; D001435:Bacteriophages / Q000235:genetics*; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008242:Lysogeny; D010641:Phenotype; D011552:Pseudomonas Infections / Q000209:etiology / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000502:physiology*
D000464:Alginates