title: [Demonstration of a tetracycline-resistance factor in a genital Mycoplasma strain. Clinical and molecular biology aspects of Ureaplasma coinfected penicilliń and tetracycline-resistant gonorrhea].
abstract: We report a male patient with severe penicillin-resistant gonococcal urethritis, coinfected with a tetracycline resistant strain of ureaplasma urealyticum. Ureaplasmas are frequently involved in gonococcal urethritis and commonly this organism may persist after the penicillin therapy causing a "post-gonoccal-urethritis" (PGU). Additional treatment with tetracyclines prove to be successful in most of these patients except in cases of tetracycline resistance in ureaplasma urealyticum. In a case like this erythromycin may be useful, a drug to which these isolates are sensitive. The microbiological and genetic feature of a tetracycline resistant strain of ureaplasma urealyticum is presented in detail. The clinical and epidemiological importance of these results are discussed and compared with the literature.
mesh_terms: D000328:Adult; D005832:Genital Diseases, Male / Q000150:complications / Q000382:microbiology*; D006069:Gonorrhea / Q000150:complications / Q000382:microbiology*; D006801:Humans; D008297:Male; D009175:Mycoplasma Infections / Q000150:complications / Q000382:microbiology*; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000235:genetics*; D010403:Penicillin Resistance; D011815:R Factors; D013752:Tetracycline / Q000494:pharmacology*; D014509:Ureaplasma / Q000187:drug effects / Q000235:genetics*
chemical_list: D013752:Tetracycline
vernacular_title: Nachweis eines Tetracyclin-Resistenzfaktors bei einem genitalen Mykoplasmenstamm. Klinische und molekularbiologische Aspekte einer mit Ureaplasmen mischinfiziertem penicillin- und tetracyclineresistenten Gonorrhoe.