title: [Mechanism of action of Pseudomonas aeruginosa exotoxin on the macroorganism (experimental studies)].
abstract: Some problems of the pathogenic action of P. aeruginosa exotoxin on the body have been experimentally studied. Under the conditions of intoxication produced by P. aeruginosa exotoxin pronounced functional disturbances in the main parameters of central hemodynamics and changes in the coagulation properties of the blood and in the free-radical peroxidation of lipids have been found to occur. The manifestation of pathological changes has been shown to have certain specific features in different organs and to depend on the time elapsed after the introduction of exotoxin into the animals.
mesh_terms: D000818:Animals; D001769:Blood / Q000187:drug effects; D001777:Blood Coagulation / Q000187:drug effects; D004285:Dogs; D005098:Exotoxins / Q000506:poisoning / Q000633:toxicity*; D006439:Hemodynamics / Q000187:drug effects; D008163:Luminescent Measurements; D008297:Male; D011550:Pseudomonas aeruginosa; D011817:Rabbits; D051381:Rats; D013997:Time Factors
chemical_list: D005098:Exotoxins
vernacular_title: Mekhanizm deĭstviia ékzotoksina Pseudomonas aeruginosa na makroorganizm (éksperimental'nye issledovaniia).