title: Solitary cold thyroid nodule: cost-ineffectiveness of ultrasonography.
abstract: We reviewed our experience with thyroid sonography of 60 patients with nonfunctioning (cold) solitary thyroid nodules proven by iodine 123 scan. Twenty-two patients had surgery; the remaining 38 had thyroid scan and ultrasound only. In the first group, the echograms did not demonstrate the surgically proven nodules in seven patients (32%). In the second group, the thyroid echograms were reported as negative in 12 patients (32%). Two of these patients had computerized tomography (CT) which confirmed the solitary nodule identified on the 123I scan. As a consequence, we no longer perform or recommend routine thyroid echograms on all scintigraphically cold solitary nodules. We believe that the extra cost of a thyroid echogram is not justified and that the most rational application of thyroid ultrasonography is in assessing the response of a nodule to suppressive hormonal therapy.
mesh_terms: D003362:Cost-Benefit Analysis; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D006801:Humans; D007457:Iodine Radioisotopes; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013964:Thyroid Neoplasms / Q000175:diagnosis; D014463:Ultrasonography / Q000191:economics*; D014481:United States
chemical_list: D007457:Iodine Radioisotopes