Inhibition of tumor promotion by a lecanoric acid analogue.
3',5'-Dichloro-2,4'-dihydroxybenzanilide, an inhibitor of histidine decarboxylase, inhibited skin tumor promotion induced by 12-O-tetradecanoylphorbol-13-acetate in mice.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D016861:Cyclooxygenase Inhibitors; D005260:Female; D006640:Histidine Decarboxylase / Q000037:antagonists & inhibitors; D051379:Mice; D012457:Salicylamides / Q000627:therapeutic use*; D012458:Salicylanilides / Q000494:pharmacology / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D013755:Tetradecanoylphorbol Acetate
D001095:Arachidonic Acids; D016861:Cyclooxygenase Inhibitors; D012457:Salicylamides; D012458:Salicylanilides; D016718:Arachidonic Acid; C033521:SD 170; D006640:Histidine Decarboxylase; D013755:Tetradecanoylphorbol Acetate