[HLA-DRw typing in 40 patients with psoriasis].
40 unrelated patients with psoriasis vulgaris were studied for their HLA-A, B and DRw antigens phenotypes. All underwent a skin biopsy to confirm diagnosis. Like most of the authors, we observed an increase in B 13 and B 17 antigens (17,50 % and 25 %) whereas in the healthy populations the percentage was (5 % and 6,02 %) respectively. The strongest increase in DRw7 suggest that the psoriasis vulgaris was associated with DRw7 antigens, with a linkage desequilibrium between the B 13 and DRw7 antigens and between the B 17 and DRw7 antigens.
D008040:Genetic Linkage; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006684:HLA-DR Antigens; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D011565:Psoriasis / Q000276:immunology*; D012867:Skin / Q000276:immunology
D006680:HLA Antigens; D006684:HLA-DR Antigens
Groupage HLA-DRw chez 40 patients atteints de psoriasis.