Concentration of In-111-oxine-labeled autologous leukocytes in noninfected and nonrejecting renal allografts: concise communication.
Autologous leukocytes labeled with In-111 oxine (ILL) concentrated in the renal allografts of eight patients for whom transplant rejection, infection, or acute tubular necrosis (ATN) could be excluded. All patients had good-to-adequate renal function at the time of ILL scintigraphy, and none developed rejection or renal transplant failure during a 1-mo follow-up period. It is concluded that normally functioning renal allografts without evidence of rejection, infection, or ATN often will concentrate ILL. When a baseline study is not available for comparison, this phenomenon limits the value of ILL scintigraphy as a diagnostic test for transplant rejection or infection.
D000328:Adult; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D006912:Hydroxyquinolines; D007204:Indium; D007668:Kidney / Q000000981:diagnostic imaging; D016030:Kidney Transplantation; D007962:Leukocytes / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013997:Time Factors; D014184:Transplantation, Homologous
D006912:Hydroxyquinolines; D009942:Organometallic Compounds; D011868:Radioisotopes; D007204:Indium; C032950:indium oxine; D015125:Oxyquinoline