[Additive suppressive effect of Freund's complete adjuvant on the specific inhibition of anti-DNP immunoreaction (author's transl)].
Injection of DNP 38-Ficoll in 0,9 per cent saline causes a specific suppression of the secondary anti-DNP reaction in AJ-mice to the same antigen. This suppression is amplified by injection of the tolerogen in Freund's complete adjuvant (FCA) or by simultaneous injection of the tolerogen and FCA. --This additive suppressive effect of FCA is distinctly better if there are used small doses of tolerogen. Possible mechanisms interpreting these results are discussed.
D000818:Animals; D000921:Antibody-Producing Cells; D004136:Dinitrobenzenes / Q000276:immunology*; D005260:Female; D005362:Ficoll; D005620:Freund's Adjuvant / Q000276:immunology*; D007165:Immunosuppression Therapy; D051379:Mice; D009578:Nitrobenzenes / Q000276:immunology*; D013154:Spleen / Q000276:immunology
D004136:Dinitrobenzenes; D009578:Nitrobenzenes; D005362:Ficoll; D005620:Freund's Adjuvant
Die additive suppressive Wirkung von komplettem Freundschen Adjuvans bei der spezifischen Hemmung der Anti-DNP-Ficoll-Immunreaktion.