title: Concanavalin A binding glycoprotein in human stratum corneum.
abstract: A mannose-containing 40K glycoprotein has been identified in the stratum corneum of normal human epidermis. It is apparently membrane-bound and in the intact epidermis it is inaccessible to either concanavalin A or to trypsin. After it is detergent-solubilized, it can be labeled with concanavalin A or destroyed with trypsin. There is little or none of this glycoprotein in the viable cells of the epidermis.
mesh_terms: D001345:Autoradiography; D002352:Carrier Proteins / Q000302:isolation & purification*; D004591:Electrophoresis, Polyacrylamide Gel; D016650:Fluorescein-5-isothiocyanate; D005452:Fluoresceins; D005456:Fluorescent Dyes; D006023:Glycoproteins / Q000302:isolation & purification*; D006801:Humans; D007457:Iodine Radioisotopes; D011952:Receptors, Concanavalin A / Q000302:isolation & purification*; D012867:Skin / Q000032:analysis*; D013861:Thiocyanates
chemical_list: D002352:Carrier Proteins; D005452:Fluoresceins; D005456:Fluorescent Dyes; D006023:Glycoproteins; D007457:Iodine Radioisotopes; D011952:Receptors, Concanavalin A; D013861:Thiocyanates; C027774:concanavalin A-binding glycoproteins; D016650:Fluorescein-5-isothiocyanate