Estimation of glomerular filtration rate, without blood samples, during renography.
The radiotracer 99Tcm DTPA is cleared from the blood by glomerular filtration. Measurement of the clearance rate of a radionuclide has previously required serial blood samples taken over a period of several hours. This report describes a technique where no blood samples are necessary and glomerular filtration rate (GFR) and relative function can be determined prior to the excretion phase in routine renography after tracer arrival in the kidneys. The percentage uptake values for 20 patients were correlated with GFR values from 51Cr EDTA clearance tests.
D000328:Adult; D000368:Aged; D002860:Chromium Radioisotopes; D004492:Edetic Acid; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D004369:Pentetic Acid; D011866:Radioisotope Renography; D013667:Technetium; D016284:Technetium Tc 99m Pentetate
D002860:Chromium Radioisotopes; D013667:Technetium; D004369:Pentetic Acid; D004492:Edetic Acid; D016284:Technetium Tc 99m Pentetate