Chemical induction of ovarian epithelial carcinoma in mice.
Murine ovaries were treated with silk sutures saturated with a solution of 7,12-dimethylbenz(a)anthracene in beeswax. One of 35 animals developed an epithelial carcinoma. This tumor was not successfully transplanted into young animals.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000230:Adenocarcinoma / Q000139:chemically induced / Q000473:pathology / Q000648:ultrastructure; D000818:Animals; D001551:Benz(a)Anthracenes; D005260:Female; D051379:Mice; D008809:Mice, Inbred C3H; D008854:Microscopy, Electron; D010051:Ovarian Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000648:ultrastructure
D001551:Benz(a)Anthracenes; D015127:9,10-Dimethyl-1,2-benzanthracene