title: Penicillin-binding proteins and peptidoglycan peptide-interacting proteins.
abstract: Peptidoglycan peptide-interacting proteins (PPIPs) which include the penicillin-binding proteins (PBPs) are bacterial enzymes which interact with beta-lactams (including penicillins and cephalosporins) and/or acyl-D-ala-D-ala analogues of a non-beta-lactam structure. The PBPs and other PPIPs of Escherichia coli are reviewed.
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology; D001426:Bacterial Proteins / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D006602:Hexosyltransferases; D007769:Lactams; D002267:Muramoylpentapeptide Carboxypeptidase / Q000378:metabolism*; D046915:Penicillin-Binding Proteins; D010406:Penicillins / Q000378:metabolism / Q000494:pharmacology; D010457:Peptidoglycan / Q000378:metabolism*; D010458:Peptidyl Transferases
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002352:Carrier Proteins; D007769:Lactams; D046915:Penicillin-Binding Proteins; D010406:Penicillins; D010457:Peptidoglycan; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase