title: [Radiotherapy and chemoradiotherapy of neglected forms of malignant oropharyngeal tumors].
abstract: Open-field gamma-beam therapy using grid filters was used for 53 patients with Stage III-III stomatopharyngeal tumors. Besides, to compare therapeutic efficacy the 2nd group was taken (52 persons with Stage III-IV) where chemotherapy was used simultaneously. Single and summary radiation doses did not lower. A chemotherapeutic agent dose was equal to 1/2 up to 2/3 of the standard one. Powerful substitution and hemostimulation therapy and a great variety of drugs were employed not to induce deep changes of hemopoiesis and immunosuppression. A single focal dose in gamma-beam therapy varied from 1.6 to 2.5 Gy, the summary dose from 55 to 70 Gy depending on the stage of disease and the histological structure of a tumor. The prescription of one or another chemotherapeutic agent was mainly determined by the morphological structure of a tumor.
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005720:Gamma Rays; D006801:Humans; D008558:Melphalan / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D010610:Pharyngeal Neoplasms / Q000628:therapy*; D011379:Prognosis; D012509:Sarcoma / Q000188:drug therapy / Q000532:radiotherapy; D013852:Thiotepa / Q000627:therapeutic use
chemical_list: D003520:Cyclophosphamide; D013852:Thiotepa; D008558:Melphalan; D008727:Methotrexate
vernacular_title: Luchevaia i khimioluchevaia terapiia zapushchennykh form zlokachestvennykh novoobrazovaniĭ rotoglotki.