Benign fibroblastic tumor-like lesion simulating malignancy in the maxilla.
A benign fibroblastic lesion simulating malignancy is reported. The lesion occurred in the right maxilla of an 11-year-old girl and perforated the outer cortical plate, suggesting malignancy. The biopsy, however, revealed proliferation of fibroblasts and fibrocytes with neither prominent atypia nor mitosis in a myxoid matrix. Electron microscopy showed that some fibroblastic cells were indeed myofibroblasts. As the lesion did not belong to any established entities, the final pathological diagnosis of benign fibroblastic lesion was made, leading to conservative surgery. The patient is well without recurrence 18 months after surgery.
D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology / Q000648:ultrastructure; D005350:Fibroma / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000473:pathology; D006801:Humans; D008439:Maxillary Diseases / Q000473:pathology*; D008441:Maxillary Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron