title: DNA sequence encoding the NH2-terminal peptide involved in transport of lambda receptor, an Escherichia coli secretory protein.
abstract: lamB encodes the lambda receptor of Escherichia coli, an outer membrane protein. We have identified the beginning of the lamB gene by correlating DNA nucleotide sequence with a partial sequence of the primary translation product of lamB. We show that lambda receptor is synthesized as a precursor containing an extra 25 amino acids at its NH2 terminus. These amino acids are predominately hydrophobic and probably comprise a structure required for initiation of transport of lambda receptor from the cytoplasm to the outer membrane.
mesh_terms: D000595:Amino Acid Sequence; D010582:Bacteriophage lambda / Q000378:metabolism*; D001483:Base Sequence; D002352:Carrier Proteins / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes; D006868:Hydrolysis; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D011498:Protein Precursors / Q000235:genetics*; D011991:Receptors, Virus / Q000235:genetics*
chemical_list: D002352:Carrier Proteins; D004269:DNA, Bacterial; D008565:Membrane Proteins; D011498:Protein Precursors; D011991:Receptors, Virus