Pseudomonas aeruginosa. I. Large-volume cultivation of production strains for vaccination purposes.
A submerged culture technology was used to produce large-volume suspensions of Pseudomonas aeruginosa production strain for the purpose of vaccination. This paper describes the composition of the culture media used and the methods of preparing endotoxin and exotoxin components of the desired immunogenic activity.
D000942:Antigens, Bacterial / Q000302:isolation & purification; D003470:Culture Media; D005285:Fermentation; D006460:Hemolysin Proteins / Q000302:isolation & purification; D006801:Humans; D011552:Pseudomonas Infections / Q000517:prevention & control; D011550:Pseudomonas aeruginosa / Q000254:growth & development* / Q000276:immunology; D014612:Vaccines
D000942:Antigens, Bacterial; D003470:Culture Media; D006460:Hemolysin Proteins; D014612:Vaccines