title: [R-(Z)]-4-amino-3-chloro-2-pentenedioic acid, a new antibiotic. Fermentation, isolation and characterization.
abstract: A new unsaturated glutamic acid analog, 4-amino-3-chloro-2-pentenedioic acid ( ACPA ) was isolated from a fermentation broth produced by a strain of Streptomyces. ACPA has a very narrow antibacterial spectrum, which is virtually limited to Micrococcus luteus.
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D001412:Bacillus subtilis / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005285:Fermentation; D005971:Glutamates / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008837:Micrococcus / Q000187:drug effects; D013302:Streptomyces / Q000378:metabolism; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D005971:Glutamates; C041409:4-amino-3-chloro-2-pentenedioic acid