3-N-substituted-amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazolines have enhanced activity against arachidonate 5-lipoxygenase and cyclooxygenase.
D015772:4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; D000478:Alkylation; D000818:Animals; D001091:Arachidonate Lipoxygenases; D055598:Chemical Phenomena; D002621:Chemistry; D016861:Cyclooxygenase Inhibitors; D066298:In Vitro Techniques; D016859:Lipoxygenase Inhibitors; D009584:Nitrogen; D011720:Pyrazoles / Q000494:pharmacology*; D011817:Rabbits; D013329:Structure-Activity Relationship
D016861:Cyclooxygenase Inhibitors; D016859:Lipoxygenase Inhibitors; D011720:Pyrazoles; D015772:4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; D001091:Arachidonate Lipoxygenases; D009584:Nitrogen