title: Hypothalamic polar spongioblastoma associated with the diencephalic syndrome. Ultrastructural demonstration of a neuro-endocrine organization.
abstract: A tumor was resected from the third ventricle of a four years and eleven month old girl with the diencephalic syndrome. By light microscopy, it was diagnosed as a polar spongioblastoma . Its ultrastructural study was undertaken and the features were found to be distinctive and previously unreported. The organization of the neoplasm was similar to that of the hypothalamic neuro-endocrine systems: Cellular perivascular arrangement with intra-cytoplasmic microtubules and membrane bound dense-core granules.
mesh_terms: D001254:Astrocytoma / Q000150:complications* / Q000648:ultrastructure; D001932:Brain Neoplasms / Q000150:complications* / Q000648:ultrastructure; D002675:Child, Preschool; D004027:Diencephalon / Q000648:ultrastructure*; D004614:Emaciation / Q000209:etiology; D004700:Endocrine System Diseases / Q000209:etiology; D005183:Failure to Thrive / Q000209:etiology; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000648:ultrastructure*; D008854:Microscopy, Electron; D013577:Syndrome