title: Operations upon the biliary tract in patients with acute pancreatitis: aims, indications and timing.
abstract: The management of gallstones in patients with acute pancreatitis (AP) is controversial. This paper reports an analysis of 171 attacks of AP associated with gallstones. Whilst awaiting elective cholecystectomy 56% of patients had further symptoms and 1 died. Non-urgent operations during the same admission as the pancreatitis (n = 34) resulted in 2 deaths and 7 septic complications, but prediction of complications may be possible. Urgent surgery (n = 5) was followed by 3 deaths. This study suggests that in most patients, cholecystectomy should be performed as soon as the patient is adequately fit. Urgent removal of an impacted ampullary stone (preferably by endoscopic papillotomy) may be required in a small minority if severe pancreatitis fails to respond to medical treatment, or if cholangitis supervenes .
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000601:surgery; D001662:Biliary Tract Surgical Procedures; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery; D005260:Female; D042882:Gallstones / Q000150:complications / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications; D012008:Recurrence; D012189:Retrospective Studies; D013997:Time Factors