[Phenotype of T lymphocytes and macrophages obtained by broncho-alveolar lavage of human lung].
T lymphocytes and macrophages, isolated and purified from broncho-alveolar lavages performed in normal controls and in patients with various alveolar structure diseases were identified using monoclonal antibodies against different membrane markers. For T lymphocyte subsets, our results are consistent with previous observations showing a large number of lung helper T cells in patients with sarcoidosis with high-intensity alveolitis. For macrophage subsets, we pointed out, for all cases, a weak expression of monocyte markers.
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis; D001980:Bronchi; D002462:Cell Membrane / Q000276:immunology; D006801:Humans; D008264:Macrophages / Q000166:cytology* / Q000276:immunology; D010641:Phenotype; D011650:Pulmonary Alveoli; D013601:T-Lymphocytes / Q000166:cytology* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface
Etude du phénotype des lymphocytes T et des macrophages recueillis par lavage broncho-alvéolaire du poumon humain.