title: Intrauterine growth retardation.
abstract: Fetal growth retardation ranks third after prematurity and malformations as a cause of perinatal deaths. Antenatal fetal monitoring (biochemical testing of fetoplacental function plus cardiotocography) has emerged as the most important means of reduction in the number of stillbirths and improvement in the quality of survival of infants who are born alive. Clinical acumen combined with biochemical and/or ultrasonographic testing will identify no more than 70% of growth retarded fetuses. However, not all small for dates fetuses are at risk, and many doomed to die in utero are not by definition, growth retarded. It should be the obstetrician's aim to identify the fetus at risk of death from hypoxia whether growth retarded or not. Biochemical and ultrasonographic methods of testing are not truly comparable, since some aim to identify the growth retarded fetus, irrespective of his state of health, whereas others aim to detect fetoplacental dysfunction, irrespective of whether or not the fetus is growth retarded. With present methods of antenatal diagnosis and treatment and timing of delivery determined by nonstressed cardiotocography, the physical and intellectual prognosis of growth retarded infants is most satisfactory; follow-up studies have shown that only about 2% of these infants are severely handicapped.
mesh_terms: D036861:Delivery, Obstetric; D004964:Estriol / Q000652:urine; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D005318:Fetal Heart / Q000502:physiology; D005311:Fetal Hypoxia / Q000150:complications; D005323:Fetal Monitoring; D005500:Follow-Up Studies; D005865:Gestational Age; D006339:Heart Rate; D006801:Humans; D007231:Infant, Newborn; D010289:Parenteral Nutrition, Total; D011247:Pregnancy; D011248:Pregnancy Complications; D011296:Prenatal Diagnosis; D011379:Prognosis; D012959:Socioeconomic Factors; D013997:Time Factors; D014463:Ultrasonography
chemical_list: D004964:Estriol