IgD plasma cell leukemia and uterine malignant mixed Müllerian tumor.
The case of a 74-year-old female with an IgD kappa plasma cell leukemia is presented. In contrast to the majority of the cases in the literature, this patient responded rather well to melphalan and prednisolone and survived for 20 months after starting treatment. Another remarkable feature was the simultaneous occurrence of a double uterine neoplasm, a malignant mixed Müllerian tumor of the homologous variety (also called carcinosarcoma).
D000290:Adnexa Uteri / Q000601:surgery; D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use; D000667:Ampicillin / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000150:complications*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007044:Hysterectomy; D007072:Immunoglobulin D / Q000378:metabolism; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D007952:Leukemia, Plasma Cell / Q000150:complications* / Q000188:drug therapy; D008558:Melphalan / Q000627:therapeutic use; D011014:Pneumonia / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D014594:Uterine Neoplasms / Q000150:complications* / Q000601:surgery
D005839:Gentamicins; D007072:Immunoglobulin D; D007145:Immunoglobulin kappa-Chains; D000493:Allopurinol; D000667:Ampicillin; D011239:Prednisolone; D008558:Melphalan