Hyperparathyroidism after neck irradiation for Hodgkin's disease.
A 38-year old man developed hypercalcaemia 13 years after treatment with mantle field radiation for Hodgkin's disease. A parathyroid tumour was removed surgically. The histological diagnosis was parathyroid adenoma with marked central fibrosis. Hyperparathyroidism as a possible late complication of radiation therapy of malignant diseases has, to our knowledge, not been described before. Key words: Hodgkin's disease, hyperparathyroidism, irradiation, parathyroid adenoma.
D000236:Adenoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000209:etiology*; D008198:Lymph Nodes / Q000528:radiation effects*; D008297:Male; D009333:Neck / Q000528:radiation effects; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000209:etiology* / Q000473:pathology; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*