Structure and evolution of human Y chromosome DNA.
Two repeated sequences account for 70% of the DNA of the human Y chromosome. They are located in the heterochromatin of the long arm. These sequences are related to others found on human chimpanzee and gorilla autosomes, and on the human X chromosome but have diverged in a characteristic way from the non Y copies. They have no detectable phenotypic effect when translocated to autosomes. We have cloned DNA from the human Y chromosome using fluorescence activated cell sorting. At least one single copy sequence is present on both the X and Y chromosomes.
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D004247:DNA / Q000235:genetics*; D005260:Female; D006071:Gorilla gorilla; D006801:Humans; D008297:Male; D002679:Pan troglodytes; D010641:Phenotype; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid; D014998:Y Chromosome
D004247:DNA