title: Trisomy 21 mosaicism in two successive generations in a family.
abstract: The occurrence of 46,XX/47,XX,+21 mosaicism in two successive generations implies an aetiological relationship between the 47,XX,+21 cell line of the mother and her daughter.
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D002904:Chromosomes, Human, 21-22 and Y; D004314:Down Syndrome / Q000235:genetics*; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000648:ultrastructure; D008875:Middle Aged; D008938:Mitosis; D009030:Mosaicism; D010053:Ovary / Q000648:ultrastructure