[Chemiluminescence of thrombocytes in thrombin-induced aggregation].
Chemoluminescence induced by thrombin and aggregation of thrombocytes as well as effect of aspirin on the reactions were studied. Intensity of thrombin-induced chemoluminescence correlated with accumulation of malonic dialdehyde and hydroperoxides in cells. Chemoluminescence of thrombocytes appears to occur after the thrombin stimulation of cyclooxygenase pathway of arachidonic acid oxidation in cells.
D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000097:blood; D001241:Aspirin / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects*; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood; D066298:In Vitro Techniques; D008163:Luminescent Measurements; D008315:Malondialdehyde / Q000097:blood; D010974:Platelet Aggregation / Q000187:drug effects*; D013917:Thrombin / Q000494:pharmacology*
D001095:Arachidonic Acids; D016718:Arachidonic Acid; D008315:Malondialdehyde; D006861:Hydrogen Peroxide; D013917:Thrombin; D001241:Aspirin
Khemiliuminestsentsiia trombotsitov pri indutsiruemoĭ trombinom agregatsii.