[Ftorafur interaction with biopolymers].
High resolution NMR spectra were studied on 1H, 13C and 19F nuclei of antitumor drug ftorafur . The lines in NMR spectrum of 1H and 19F representing individual fragments of ftorafur molecule were shown to be broadened in the presence of BSA and DNA. These broadenings reflect the formation mechanisms of ftorafur complexes with indicated biopolymers during transport and antitumor effect of the drug.
D000818:Animals; D001704:Biopolymers; D002417:Cattle; D004247:DNA; D005472:Fluorouracil / Q000031:analogs & derivatives; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D012710:Serum Albumin, Bovine; D005641:Tegafur
D001704:Biopolymers; D005641:Tegafur; D012710:Serum Albumin, Bovine; D004247:DNA; D005472:Fluorouracil
Vzaimodeĭstvie ftorafura s biopolimerami.