title: A double-blind trial of metronidazole versus oxytetracycline therapy for rosacea.
abstract: Forty patients with papulo-pustular rosacea were treated for 12 weeks on a random double-blind basis either with oxytetracycline 250 mg twice daily or with metronidazole 200 mg twice daily. Both drugs produced an improvement which was greater after 12 weeks than after 6 weeks, but there was no significant difference between them. Metronidazole appears to be a safe and effective drug for the treatment of rosacea.
mesh_terms: D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D010118:Oxytetracycline / Q000627:therapeutic use*; D012393:Rosacea / Q000188:drug therapy*
chemical_list: D008795:Metronidazole; D010118:Oxytetracycline