title: [Milk and egg antigen specific serum IgE-levels in children with allergic diseases (author's transl)].
abstract: Milk- and egg-specific serum IgE levels of 62 respiratoric and/or skin allergic children have been measured. 8 (14,5%) from clinically milk- and 3 (13,6%) of 22 egg-allergic children had abnormally high specific IgE globulin levels. The positive results were measured mostly in boys (10 boys from 11 positive patients). 4 children (28,5%) from 14 patients with allergic diseases having low IgA levels had abnormally high specific IgE concentrations. Authors suppose that the low positivity rate is caused--besides others--by the examined antigen's heterogeneity. The RAST with complex antigens is useful to diagnose only the extreme cases. Our data show the necessity of using purified antigens, to make this method more specific.
mesh_terms: D000293:Adolescent; D000818:Animals; D000918:Antibody Specificity; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology*; D004531:Eggs; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007223:Infant; D008297:Male; D008892:Milk; D011852:Radioallergosorbent Test; D012130:Respiratory Hypersensitivity / Q000276:immunology*
chemical_list: D007073:Immunoglobulin E
vernacular_title: Untersuchung des IgE-Spiegels Milch- und Eierantigen-spezifischer Sera bei allergischen Kindern.