Pregnancy-associated molecular variants of human serum transcortin and thyroxine-binding globulin.
Affinity chromatography on immobilised concanavalin A revealed that transcortin and thyroxine-binding globulin isolated from human postpartum serum contained approximately 10% of molecular variants that did not occur in these glycoproteins isolated from normal donor serum (both male and female). The chromatographic behaviour of the pregnancy-associated glycoprotein variants, their monosaccharide compositions, and the results of methylation analysis indicated that these variants contained only triantennary oligosaccharide chains of the N-acetyl-lactosamine type.
D002846:Chromatography, Affinity; D005260:Female; D006801:Humans; D008297:Male; D008745:Methylation; D009005:Monosaccharides / Q000032:analysis; D011247:Pregnancy; D013975:Thyroxine-Binding Proteins / Q000032:analysis*; D014156:Transcortin / Q000032:analysis*
D009005:Monosaccharides; D013975:Thyroxine-Binding Proteins; D014156:Transcortin