title: [Efficacy of thymostimulin in experimental combined therapy of malignant gliomas].
abstract: The authors studied the effect of one of the thymus preparations, thymostimulin, on the growth of experimental cerebral glioma. It was found that independent administration of thymostimulin at the beginning or in the second half of the latent period of tumor growth had no essential effect on the survival of rats. Injection of thymostimulin during chemotherapy with fluorafur increased the survival of rats considerably, both in early and in late immunotherapy.
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D001932:Brain Neoplasms / Q000188:drug therapy*; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives*; D005910:Glioma / Q000188:drug therapy*; D008297:Male; D009368:Neoplasm Transplantation; D051381:Rats; D005641:Tegafur / Q000008:administration & dosage*; D013949:Thymus Extracts / Q000008:administration & dosage*
chemical_list: D013949:Thymus Extracts; C031407:thymostimulin; D005641:Tegafur; D005472:Fluorouracil
vernacular_title: Ob éffektivnosti timostimulina pri kombinirovannoĭ terapii zlokachestvennykh gliom v éksperimente.