HLA, immunoglobulin allotypes and cell-mediated immunity in retinitis pigmentosa: a family study.
Investigation of an informative family including two probands with male multiplex retinitis pigmentosa revealed that the putative disease susceptibility loci were not linked to those of HLA. In addition, analysis of immunological data obtained yielded evidence suggestive of X-linked inheritance of susceptibility to cell-mediated immune aberration in this family.
D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007142:Immunoglobulin gamma-Chains / Q000235:genetics*; D008297:Male; D010375:Pedigree; D012174:Retinitis Pigmentosa / Q000235:genetics / Q000276:immunology*
D006680:HLA Antigens; D007126:Immunoglobulin Allotypes; D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains