title: [Hormonal findings in children with central manifestations of Recklinghausen's neurofibromatosis].
abstract: Hormone parameters were evaluated in 14 children with cerebral manifestation of N.R. to find a possible involvement of the hypothalamo-pituitary axis. In addition to growth hormone and prolactin stimulation, tests of gonadotropic, thyreotropic and adrenocorticotropic function were performed. 6 patients had insufficient growth hormone secretory capacity, and 6 times an increased prolactin-stimulation was found; in one patient ACTH-reserve was diminished. A brain tumour was found in 5 of these 8 patients with impaired hormone results; however, in 3 cases pathologic results were found only after operation.
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D011388:Prolactin / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D013974:Thyroxine; D006854:Hydrocortisone
vernacular_title: Hormonelle Befunde bei Kindern mit zentraler Manifestation einer Neurofibromatose Recklinghausen.