[Direct IgG-mediated reactivity of human neutrophils to Corynebacterium diphtheriae peptidoglycan].
The direct and IgG-mediated reactivity to C. diphtheriae peptidoglycan in the system of neutrophilic phagocytosis was studied. Peptidoglycan treated with IgG (2-20 mg/ml) isolated from commercial immunoglobulin stimulated the reduction of nitro blue tetrazolium by human neutrophils. Direct (IgG-independent) reactions were much less intensive. The problem of normal IgG opsonizing C. diphtheriae peptidoglycan is discussed.
D003353:Corynebacterium diphtheriae / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism; D009580:Nitroblue Tetrazolium / Q000378:metabolism; D009895:Opsonin Proteins / Q000276:immunology; D010084:Oxidation-Reduction; D010457:Peptidoglycan / Q000276:immunology*
D007074:Immunoglobulin G; D009895:Opsonin Proteins; D010457:Peptidoglycan; D009580:Nitroblue Tetrazolium
Priamaia IgG-oposredovannaia reaktivnost' neĭtrofilov cheloveka k peptidoglikanu Corynebacterium diphtheriae.