Monoclonal gammopathy in patients with chronic and acute myeloid leukemia.
Monoclonal IgG components were found in the serum of 5 of 40 patients with chronic myelocytic leukemia (12.5%), as well as in 2 of 15 patients with acute myelocytic leukemia (13.3%). These findings may represent an involvement of the lymphoplasmacytic system in myeloproliferative disorders. The significance of this association is discussed.
D000328:Adult; D000368:Aged; D001536:Bence Jones Protein / Q000032:analysis; D001797:Blood Protein Electrophoresis; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications* / Q000276:immunology; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000032:analysis; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007951:Leukemia, Myeloid / Q000150:complications* / Q000276:immunology; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D001536:Bence Jones Protein