Cotransformation of a serum resistance phenotype with genes for arginine biosynthesis in Neisseria gonorrhoeae.
Two genes (arg-3 and arp-6) marked by arginine auxotrophy and a gene (sac-2) marked by resistance to serum killing were found to be linked by cotransformation. Evidence derived from the linkage of these markers to spc (spectinomycin resistance) suggests that sac-2 may be genetically distinct from a sac gene previously described.
D001120:Arginine / Q000096:biosynthesis*; D001770:Blood Bactericidal Activity; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000502:physiology; D005796:Genes; D008040:Genetic Linkage; D009344:Neisseria gonorrhoeae / Q000235:genetics*; D000198:Spectinomycin / Q000494:pharmacology; D014169:Transformation, Bacterial
D000198:Spectinomycin; D001120:Arginine