title: [Urinary excretion of nitrogen from 15N leucine during infusion of an amino acids solution rich in branched amino acids].
abstract: Branched chain amino acid enriched solutions have been proposed in several situations. The fate of the nitrogen contained in those amino acids, particularly the immediate urinary excretion, has not been established yet. In the present study, the rates of urea and total urinary nitrogen loss from 15N leucine were measured in a patient receiving a branched chain amino acid enriched solution. The results showed that: 1) the urinary excretion of leucine represented less than 1% of the amount of injected leucine; 2) 15N excreted from leucine was 5.37% of the 15N injected during the 24 h of the infusion and 7.66% during the following day; 3) the excretion of 15N urea represented 62% of the total 15N excreted during the first 24 h and 72% for the following day. Finally, in this patient, the amount of nitrogen from leucine immediately excreted in the urine was moderate.
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage* / Q000378:metabolism; D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage; D006801:Humans; D007930:Leucine / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000652:urine*; D009587:Nitrogen Isotopes; D010288:Parenteral Nutrition / Q000379:methods*; D010289:Parenteral Nutrition, Total / Q000379:methods*
chemical_list: D000596:Amino Acids; D000597:Amino Acids, Branched-Chain; D009587:Nitrogen Isotopes; D007930:Leucine; D009584:Nitrogen
vernacular_title: Excrétion urinaire de l'azote de la 15N leucine au cours de la perfusion d'un soluté d'aminoacides riche en acides aminés ramifiés.