Necrotropic protective effect of Ca-Mg gluconolactate on allyl alcohol-induced liver necrosis in rats.
The prevention of liver damage in rats intoxicated with allyl alcohol was attempted with 5 per cent Ca--Mg gluconolactate in reiterated doses. This preparation prevented or reduced liver necrosis only in the presence of spleen: splenectomy annihilated the effect of Ca--Mg gluconolactate.
D000433:1-Propanol / Q000009:adverse effects; D000818:Animals; D005942:Gluconates / Q000494:pharmacology*; D007773:Lactates / Q000494:pharmacology*; D008103:Liver Cirrhosis / Q000139:chemically induced*; D020005:Propanols; D051381:Rats
C024985:Ca-Mg gluconolactate; D005942:Gluconates; D007773:Lactates; D020005:Propanols; C006463:allyl alcohol; D000433:1-Propanol