title: Helical macrofiber formation in Bacillus subtilis: inhibition by penicillin G.
abstract: The folding process required for helical macrofiber formation after the outgrowth of Bacillus subtilis spores was found to be blocked by very low concentrations of penicillin G (1 to 3 ng/ml). Under such conditions, growth and septation without cell separation resulted in characteristic disorganized multicellular structures. Higher concentrations (4 and 10 ng/ml) were needed to inhibit spore outgrowth and vegetative growth, respectively.
mesh_terms: D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development* / Q000648:ultrastructure; D010400:Penicillin G / Q000633:toxicity*; D013171:Spores, Bacterial / Q000187:drug effects / Q000254:growth & development / Q000648:ultrastructure
chemical_list: D010400:Penicillin G