Localization of the pyroantimonate-bound cations in the pancreatic B-cells organelles and their variations.
The heterogeneity of the localization of the pyroantimonate-bound cations in different B cell's organelles of normoglycemic and glucose-treated white rats was investigated. Its different variations are systematically described. It is pointed out that an active or nonactive type of localization may be presumed only after a multifactor statistical analysis. It is supposed the localization's heterogeneity of the reactive product to reflect the functional heterogeneity of the cell organelles during the secretory cycle. The pyroantimonate method is assumed to show not so much the distribution of the respective cations as the dynamic changes of pH taking place in the different compartments of the B cell.
D000818:Animals; D000965:Antimony; D002412:Cations / Q000302:isolation & purification*; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006651:Histocytochemistry; D007275:Injections, Intravenous; D007515:Islets of Langerhans / Q000032:analysis* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009940:Organoids / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D002412:Cations; C009133:pyroantimonate; D000965:Antimony; D005947:Glucose