[Production of complement C 3 fraction by rat liver epithelial cells in culture. Stimulating effect of monocyte supernatants from human circulating blood].
A noticeable increase has been observed in the production of the C 3 component of the complement by Rat liver epithelial cells cultured in vitro in the presence of small quantities of supernatant of human blood mononuclear cells cultured for 72 hrs. with phytohemagglutinin. The physicochemical properties suggest that the stimulating factor(s) is(are) protein(s).
D000818:Animals; D002478:Cells, Cultured; D003176:Complement C3 / Q000096:biosynthesis*; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism*; D010835:Phytohemagglutinins / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D003176:Complement C3; D010835:Phytohemagglutinins
Production de la fraction C3 du complément par des cellules épithéliales de foie de rat en culture. Effet stimulant de surnageants de lymphomonocytes du sang circulant humain.