title: [Erythromelanoderma in pemphigus herpetiformis associated with eosinophilic spongiosis].
abstract: A 62 year old female was treated for several years with DDS because of Duhring-disease like symptoms. She developed erythro-melanoderma, generalized lymphadenitis and pachyderma. Histologically there were eosinophilic spongiosis and intraepidermal vesiculation, blood eosinophilia up to 42%, and intercurrent streptococcal septicemia, immunohistologically in vivo bound pemphigus antibody, but no papillary or linear IgA. Indirect immunofluorescence was negative. Paraproteinemia was excluded.
mesh_terms: D003622:Dapsone / Q000627:therapeutic use; D003873:Dermatitis, Exfoliative / Q000150:complications* / Q000473:pathology; D004802:Eosinophilia / Q000150:complications*; D005260:Female; D006801:Humans; D008548:Melanosis / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D010392:Pemphigus / Q000150:complications* / Q000473:pathology; D018805:Sepsis / Q000150:complications; D013290:Streptococcal Infections / Q000150:complications
chemical_list: D003622:Dapsone
vernacular_title: Erythromelanodermie bei "Pemphigus herpetiformis" mit eosinophiler Spongiose.