title: [Nuclear spin tomographic diagnosis of brain tumors using the contrast medium gadolinium-DTPA].
abstract: This study examines the effect of the NMR contrast medium gadolinium-DTPA on image contrast in cerebral tumours. Sixteen patients with space-occupying cerebral lesions were examined on a 0.35 Tesla superconducting scanner, using a T1-weighted spinecho sequence prior to and after the intravenous application of gadolinium-DTPA. In 8 patients T2-weighted spinecho-sequences were obtained before the administration of contrast. The tomograms were evaluated visually and according to quantitative criteria. The use of gadolinium-DTPA helps to evaluate the blood-brain barrier and improves diagnosis by differentiating tumour tissue from edema and from normal brain tissue.
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary; D005260:Female; D005682:Gadolinium; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D004369:Pentetic Acid; D010865:Pilot Projects; D014057:Tomography, X-Ray Computed
chemical_list: D004369:Pentetic Acid; D005682:Gadolinium
vernacular_title: Kernspintomographische Diagnostik von Hirntumoren mit dem Kontrastmittel Gadolinium-DTPA.