Serologic and biochemical studies of a previously unclassified blood type B variant.
The designation B4 is proposed for a weak variant of type B blood found in a Salvadorian woman and her two daughters. The red cells were weakly agglutinated by anti-B and anti-A,B; the serum contained anti-B; and the saliva contained H but not B substance. Biochemical studies of the serum showed that the enzyme specified by the variant B gene had low activity and low affinity for both sugar donor and acceptor.
D000017:ABO Blood-Group System / Q000235:genetics* / Q000276:immunology; D004910:Erythrocyte Membrane / Q000201:enzymology; D005260:Female; D005700:Galactosyltransferases / Q000097:blood; D014644:Genetic Variation; D006386:Hemagglutination Tests; D006801:Humans; D007518:Isoantibodies / Q000235:genetics; D010375:Pedigree; D012463:Saliva / Q000276:immunology
D000017:ABO Blood-Group System; D007518:Isoantibodies; D005700:Galactosyltransferases