Sodium-dependent lithium ion efflux from murine neuroblastoma and rat glioma cells: a minor pathway for efflux of lithium ions.
Lithium ion efflux by murine neuroblastoma (clone N1E-115) and rat glioma (clone C6) cells was studied to determine the presence of a phloretin-sensitive sodium-lithium countertransport pathway which has been found in human erythrocytes. Although this pathway could be identified in these cultured cells, unlike that in red blood cells, it was a very minor (less than 20%) component of the overall efflux of lithium ions from these cells of nervous tissue origin.
D000818:Animals; D001692:Biological Transport; D002999:Clone Cells; D004912:Erythrocytes / Q000378:metabolism; D005910:Glioma / Q000378:metabolism; D008094:Lithium / Q000378:metabolism*; D051379:Mice; D009447:Neuroblastoma / Q000378:metabolism; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D012964:Sodium / Q000378:metabolism*
D008094:Lithium; D012964:Sodium