[Is the pars intermedia of the hypophysis responsible for provoking paradoxical sleep in pontine cats with an isolated hypophysis?].
In chronic pontine cats without hypothalamo-hypophysis, daily subcutaneous or intraventricular injection of total extracts of Bovine neuro-intermediate lobe increases both survival and quantity of paradoxical sleep, while synthetic Lysine vasopressin, Oxytocin or ACTH have no effect. Chronic pontine cats with "isolated hypophysis" have a longer survival and a more significant amount of paradoxical sleep than those without hypothalamo-hypophysis. Factor(s) liberated by pars intermedia are very likely to be responsible for the increase of PS since only pars intermedia remains functional in the "isolated hypophysis" as shown by immunocytochemical controls.
D000818:Animals; D002415:Cats; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D010902:Pituitary Gland / Q000502:physiology*; D011149:Pons / Q000502:physiology; D012895:Sleep, REM / Q000502:physiology*; D013997:Time Factors
La pars intermedia de l'hypophyse est-elle responsable du déclenchement du sommeil paradoxal chez le chat pontique avec "hypophyse isolée"?