Maprotiline poisoning: a case of cardiotoxicity and myoclonic seizures.
A 64-year-old man ingested 4500 mg of maprotiline hydrochloride. He developed major motor myoclonic seizures, first-degree AV block, intraventricular conduction delay, hypotension, and urinary retention. Myoclonic seizures have not been previously reported with maprotiline toxicity.
D000368:Aged; D000873:Anthracenes / Q000506:poisoning*; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D004831:Epilepsies, Myoclonic / Q000139:chemically induced*; D006327:Heart Block / Q000139:chemically induced*; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D008376:Maprotiline / Q000506:poisoning* / Q000627:therapeutic use; D013406:Suicide, Attempted / Q000523:psychology; D014555:Urination Disorders / Q000139:chemically induced
D000873:Anthracenes; D008376:Maprotiline