[Modification of mixed lymphocyte reactivity between DLA-identical dog sibs, after in vivo sensitization].
Mixed lymphocyte reactions (MLR) with cells from DLA-identical dog sibs are nonresponsive either in primary or in secondary interactions after in vitro priming. However, lymphocytes from animals sensitized in vivo against DLA-identical sibs can show increased proliferative response to their immunizing donor. The kinetics of this reaction are similar to MLR across the DLA-barrier, although its intensity is less important. This proliferation may reflect minor histocompatibility antigenic differences.
D000818:Animals; D001803:Blood Transfusion; D002478:Cells, Cultured; D004285:Dogs / Q000276:immunology*; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology; D016038:Skin Transplantation; D014184:Transplantation, Homologous
Modification de la réactivité lymphocytaire mixte entre chiens identiques dans le système DLA, après sensibilisation in vivo.