Ca(II)-calmodulin regulation of fungal dimorphism in Ceratocystis ulmi.
We have shown that Ca(II) ions, ethylene glycol-bis(beta-aminoethyl ether)-N,N-tetraacetic acid, LaCl3, and six known calmodulin inhibitors shift the yeast-mycelium dimorphic potential of Ceratocystis ulmi. Our data are consistent with the conclusions that Ca(II)-calmodulin interaction is necessary for mycelial growth in C. ulmi and that the absence of this interaction leads to the yeast phase.
D001203:Ascomycota / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D002147:Calmodulin / Q000037:antagonists & inhibitors / Q000502:physiology*; D004533:Egtazic Acid / Q000494:pharmacology; D007700:Kinetics; D014268:Trifluoperazine / Q000494:pharmacology; D013098:Xylariales / Q000187:drug effects / Q000502:physiology*
D002147:Calmodulin; D014268:Trifluoperazine; D004533:Egtazic Acid; D002118:Calcium