The effects of porcine follicular fluid in the postcastration rise of gonadotropins in the rabbit.
The effects of repeated administration of porcine follicular fluid (PFF) on the follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels after castration were studied in rabbits. Steroid-free dextran-charcoal extracted PFF was administered to male and female adult rabbits at 0800 and 1600 h for four days immediately following castration. Serum levels of FSH and LH were measured before, during and after the PFF administration and compared to controls. A significant increase in FSH and LH was observed within 24 h following castration in the controls. In the PFF-treated group, a clear suppression of serum FSH levels was observed during PFF administration in both males and females. FSH concentrations returned to the control levels within 24 h after PFF withdrawal. Even through LH levels showed no differences during PFF injection, compared to controls, a significant increase was observed following discontinuation of PFF administration.
D000818:Animals; D001826:Body Fluids / Q000502:physiology*; D002369:Castration; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007265:Inhibins / Q000502:physiology; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D006080:Ovarian Follicle / Q000502:physiology*; D011817:Rabbits; D011863:Radioimmunoassay; D012737:Sex Factors; D013552:Swine
D007265:Inhibins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone