Synthesis of C-beta-D-ribofuranosylacetic acid derivatives and their utilization in the synthesis of some C-nucleosides.
Reactions of chloro(alkoxycarbonyl)methylenetriphenylphosphoranes with protected D-ribofuranoses resulted in the exclusive formation of C-beta-D-ribofuranosyl glycosides, which were converted to some C-nucleosides, such as showdomycin and pyrido-[1,2-a]pyrimidine C-nucleosides.
D007202:Indicators and Reagents; D010753:Phosphoranes; D012263:Ribonucleosides / Q000138:chemical synthesis*; D012266:Ribose; D012787:Showdomycin / Q000138:chemical synthesis; D013329:Structure-Activity Relationship
D007202:Indicators and Reagents; D010753:Phosphoranes; D012263:Ribonucleosides; D012266:Ribose; D012787:Showdomycin