[Combined administration of human chorionic gonadotropin and human menopausal gonadotropin in idiopathic male infertility].
Changes in sex hormone levels, testicular volume and sperm count during hCG/hMG therapy were studied in 44 cases of idiopathic male infertility. These patients were divided into two groups and treated for 12 weeks. In group I, which consisted of 5 cases of azoospermia, 10 cases of severe oligozoospermia (less than 10 X 10(6)/ml) and 12 cases of mild oligozoospermia (10-50 X 10(6)/ml), 1,000 IU of hCG and 75 IU of hMG were both administered once a week. In group II, which consisted of 3 cases of azoospermia, 7 cases of severe oligozoospermia and 7 cases of mild oligozoospermia, 1,000 IU of hCG and 150 IU of hMG were both administered once a week. After 12 weeks, increase in sperm count was observed in 7 cases (26%) in group I and 4 cases (24%) in group II. Pregnancy was ensued in 4 cases in group I. There was no significant changes in testicular volume or sex hormone levels during hCG/hMG therapy.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D007273:Injections, Intramuscular; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008596:Menotropins / Q000008:administration & dosage*; D011388:Prolactin / Q000097:blood; D013076:Sperm Count; D013737:Testis / Q000503:physiopathology; D013739:Testosterone / Q000097:blood
D006063:Chorionic Gonadotropin; D013739:Testosterone; D008596:Menotropins; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone