Influences of dehydroepiandrosterone acetate on ovarian oocytes in mature cycling rats.
Degeneration of ovarian oocytes occurred to a remarkable extent in rats with polycystic ovaries induced by dehydroepiandrosterone acetate (DHA-Ac) administration. The ratio of degeneration oocytes, compared with the total oocytes examined, finally exceeded 70%.
D000818:Animals; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000494:pharmacology; D004971:Estrus; D005260:Female; D009865:Oocytes / Q000187:drug effects / Q000502:physiology*; D010053:Ovary / Q000502:physiology; D010063:Ovum / Q000502:physiology*; D011247:Pregnancy; D051381:Rats
D003687:Dehydroepiandrosterone; C028163:dehydroepiandrosterone acetate