Flavonoids with anti-cataract activity from Brickellia arguta.
Six flavonoids were isolated from Brickellia arguta and identified using chemical and spectral methods. The isolation and spectral data of a new flavonoid, 6- methoxykaempferol 3-O-beta-D- robinobioside (3), are reported for the first time. Three of these flavonoids were tested and showed inhibition of rat lens aldose reductase.
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors; D000818:Animals; D002386:Cataract / Q000188:drug therapy*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D066298:In Vitro Techniques; D007908:Lens, Crystalline / Q000201:enzymology; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats
D005419:Flavonoids; D000449:Aldehyde Reductase