Chemical modification of ansamitocins. III. Synthesis and biological effects of 3-acyl esters of maytansinol.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000627:therapeutic use; D055598:Chemical Phenomena; D002621:Chemistry; D008453:Maytansine / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009374:Neoplasms, Experimental / Q000188:drug therapy; D010078:Oxazines / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship; D013769:Tetrahymena pyriformis / Q000187:drug effects
D000903:Antibiotics, Antineoplastic; D010078:Oxazines; D008453:Maytansine