title: Chromosomal mutation that affects excretion of hemolysin in Escherichia coli.
abstract: Two types of mutants unable to excrete hemolysin were obtained when E. coli 5K carrying the multicopy hemolytic recombinant plasmid pANN202-312 was mutagenized with Mu d1. One type is altered in the plasmid hly-specific gene, hlyBb, but the other is caused by an insertion of Mu d1 into a chromosomal locus.
mesh_terms: D049933:Aminocoumarins; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002876:Chromosomes, Bacterial / Q000502:physiology*; D003374:Coumarins / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D006460:Hemolysin Proteins / Q000378:metabolism*; D009154:Mutation; D010957:Plasmids; D014169:Transformation, Bacterial; D001616:beta-Galactosidase / Q000235:genetics
chemical_list: D049933:Aminocoumarins; D000900:Anti-Bacterial Agents; D003374:Coumarins; D006460:Hemolysin Proteins; D001616:beta-Galactosidase; C004628:coumermycin