[Effect of thyroidin and mercazolyl on the enzyme-secreting function of the pentagastrin-stimulated stomach in the dog].
The pentagastrin effect on the stomach enzyme secretory function was found to depend on thyroid hormones: in conditions of inhibited thyroid function the activating effect of pentagastrin was reduced whereas administration of thyroidin enhanced it. Together with changes of the amount of secreted proteolytic enzymes in the gastric juice, a change in the ratio of proteases active in pH 2.0 and 3.0, was revealed.
D000818:Animals; D003543:Cysteamine / Q000008:administration & dosage; D004285:Dogs; D005753:Gastric Mucosa / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D010418:Pentagastrin / Q000008:administration & dosage / Q000494:pharmacology*; D010434:Pepsin A / Q000378:metabolism*; D013963:Thyroid Hormones / Q000008:administration & dosage / Q000502:physiology*; D013997:Time Factors
D007527:Isoenzymes; D013963:Thyroid Hormones; D003543:Cysteamine; C004227:thyroidin; D010434:Pepsin A; D010418:Pentagastrin
Vliianie tireoidina i merkazolila na fermentovydelitel'nuiu funktsiiu zheludka, stimulirovannuiu pentagastrinom, u sobak.