Preparation of dehydroepiandrosterone, testosterone and progesterone antigens through 7-carboxymethyl derivatives: characteristics of the antisera to testosterone and progesterone.
Dehydroepiandrosterone, testosterone and progesterone 7-carboxymethyl derivatives were prepared: 7 alpha and 7 beta epimers were separated and coupled to bovine serum albumin. Preliminary studies of the antisera induced by these antigens showed that they have high affinity and good specificity.
D000818:Animals; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D003429:Cross Reactions; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000276:immunology; D008722:Methods; D011374:Progesterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000276:immunology; D012710:Serum Albumin, Bovine / Q000276:immunology; D013739:Testosterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000276:immunology
C024684:7-carboxymethyl dehydroepiandrosterone; C024685:7-carboxymethyl progesterone; C024686:7-carboxymethyl testosterone; D012710:Serum Albumin, Bovine; D013739:Testosterone; D003687:Dehydroepiandrosterone; D011374:Progesterone