Partial inhibitory seizures: a report on two cases.
This paper described two epileptic children with the clinical features of tonic-clonic seizures, brief atonic episodes, drop attacks and myoclonic jerks. Patient 2 also displayed absences and behavioral disturbance with episodes of minor status epilepticus. When the patients held both arms outstretched, polygraphic records revealed the spike-and-wave (sp-w) discharges in association with the sudden dropping of an outstretched arm. The drops were due to a loss of tone recorded in deltoid muscles, and coincided with the slow wave components of bilateral sp-w complexes, predominantly on the contralateral side. In the present paper, the clinical and electrophysiologic features of this particular type of seizure are presented in detail. A cortical origin of these episodes is suggested.
D000927:Anticonvulsants / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004292:Dominance, Cerebral / Q000502:physiology; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000503:physiopathology; D004828:Epilepsies, Partial / Q000188:drug therapy / Q000503:physiopathology*; D004832:Epilepsy, Absence / Q000503:physiopathology; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009129:Muscle Tonus / Q000187:drug effects; D009132:Muscles / Q000294:innervation*; D009433:Neural Inhibition / Q000187:drug effects
D000927:Anticonvulsants