Dopa-oxidase activity on ICRC bacilli.
Presence of O-phenoloxidase is regarded as M. leprae specific character. This enzyme activity was found to be present in ICRC bacilli, Strain C-44. Though this strain is cultivable 'in vitro', the expression of DOPA-Oxidase activity strongly suggests that it carries M. leprae genome. The ICRC bacilli, therefore, may thus from a group of M. leprae culture isolates, distinct from other known cultivable mycobacteria which do not possess this enzyme activity.
D004156:Catechol Oxidase / Q000378:metabolism*; D006801:Humans; D007918:Leprosy / Q000382:microbiology*; D014442:Monophenol Monooxygenase / Q000378:metabolism*; D009162:Mycobacterium avium / Q000201:enzymology; D009166:Mycobacterium leprae / Q000201:enzymology*; D009170:Nontuberculous Mycobacteria / Q000201:enzymology; D013045:Species Specificity
D004156:Catechol Oxidase; D014442:Monophenol Monooxygenase