title: [Time related changes in the density of liver metastases after contract (a densitometric investigation with computer tomography) (author's transl)].
abstract: The present investigation is concerned with the increase in density of normal liver parenchyma and of liver metastases after the injection of contrast. Following a bolus injection (5 ml./sec.) of 390 mg. I/kg. body weight the difference in density between metastases and liver parenchyma at one minute after the injection was twice the pre-injection differential. This lead to a better differentiation of metastases from artefacts, and the ability to demonstrate liver metastases with a diameter less than 1 cm.. Computer tomography is likely to be better than sonography or liver scintigraphy. Some metastases show peripheral concentration of contrast with an apparent diminution in size at 5 to 10 minutes after the injection of contrast. Further investigation might lead to the ability to recognise the type of metastases where the primary tumour is unknown. After a plain film, computer tomography following injection of a suitable contrast medium is recommended.
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media
vernacular_title: Zeitlicher Ablauf des Dichteverhaltens von Lebermetastasen nach Kontrastmittelgabe. Eine densitometrische Untersuchung mit der Computertomographie.