Androstenedione, 17 beta-estradiol and progesterone plasma levels in gonadotropins induction of ovulation.
A comparison of peripheral patterns of androstenedione (A), 17 beta-estradiol (E2) and progesterone (P) is reported in ten infertile women during HMG-HCG induction of ovulation, in order to assess the site of ovarian secretion of plasma A and the possible influence on conception. Evidence for both the follicular and luteal secretion of plasma A is suggested, in addition to the stromal and adrenal contributions, since a highly significant (p less than 0.001) correlation between A and E2 plasma levels was shown during the treatment. In three cycles of conception, plasma A showed a periovulatory peak and drop, followed by a luteal increase, all of which are characteristic of E2.
D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy; D000735:Androstenedione / Q000097:blood*; D000818:Animals; D000858:Anovulation / Q000188:drug therapy; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy; D011374:Progesterone / Q000097:blood*; D011817:Rabbits
D006063:Chorionic Gonadotropin; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol; D008596:Menotropins