title: Anti-Jo-1 antibody: a marker for myositis with interstitial lung disease.
abstract: An autoantibody known as anti-Jo-1 antibody is found in 25% of patients with myositis. Its prevalence in patients with both myositis and cryptogenic fibrosing alveolitis was 68% (13 out of 19 patients), compared with 7.5% in patients with myositis alone (four of 53) and 3% in patients with cryptogenic fibrosing alveolitis alone (two of 62). Anti-Jo-1 antibody may be useful in indicating patients with myositis and cryptogenic fibrosing alveolitis. Raynaud's phenomenon, the sicca syndrome, and mild arthritis are also often part of the syndrome.
mesh_terms: D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D006801:Humans; D008297:Male; D008875:Middle Aged; D009220:Myositis / Q000150:complications / Q000276:immunology*; D011658:Pulmonary Fibrosis / Q000150:complications / Q000276:immunology*
chemical_list: D001323:Autoantibodies