[Antimitotic factors - chalones].
In order test the effect of liver chalone the tested substance was injected into the amniotic sac of a chicken embryo. As the results suggest, it proved possible to isolate from the liver a substance capable of affecting profoundly the proliferative activity of embryonic liver tissue. The substance was tissue-specific, species-nonspecific, and its action on the tissue was seen as reversible.
D000818:Animals; D002642:Chick Embryo; D006131:Growth Inhibitors / Q000302:isolation & purification / Q000494:pharmacology*; D007413:Intestinal Mucosa / Q000166:cytology; D008099:Liver / Q000032:analysis / Q000166:cytology; D008938:Mitosis / Q000187:drug effects*; D008940:Mitotic Index
D006131:Growth Inhibitors
Príspĕvek ke studiu antimitotických faktorů - tzv. chalonů.