title: The effect of dietary lysine levels on growth and metabolism of rainbow trout (Salmo gairdneri).
abstract: Groups of rainbow trout (Salmo gairdneri; mean weight 5 g) were given diets containing 10, 12, 14, 17, 21, 24 and 26 g lysine/kg diet for 12 weeks. By analysis of the growth values the dietary requirement of lysine in this experiment was found to be 19 g/kg diet. A similar requirement value was obtained from a dose-response curve of expired 14CO2 (following an intraperitoneal injection of L-[U-14C]lysine) v. dietary lysine concentration. Liver concentrations of total lipid and carnitine and activities of lysine-alpha-ketoglutarate reductase (saccharopine dehydrogenase (NADP+, lysine-forming), EC 1.5.1.8) in the liver were not significantly different in fish from the different dietary treatments. Hepatosomatic index, however, was higher in those fish given low levels of dietary lysine.
mesh_terms: D000818:Animals; D002331:Carnitine / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008239:Lysine / Q000378:metabolism / Q000494:pharmacology*; D009751:Nutritional Requirements; D012443:Saccharopine Dehydrogenases / Q000378:metabolism; D012487:Salmonidae / Q000254:growth & development*; D014337:Trout / Q000254:growth & development* / Q000378:metabolism
chemical_list: D012443:Saccharopine Dehydrogenases; C029496:saccharopine dehydrogenase (NADP+, lysine-forming); D008239:Lysine; D002331:Carnitine