Identifications of the intrafusal endings of skeletofusimotor axons in the cat.
Direct identification of the endings of skeletofusimotor (beta) axons has been made in muscle spindles deprived for their gamma innervation by degeneration. Hindlimb muscles were prepared in which 1--5 fast-conducting motor axons were left intact while the rest of the motor supply was cut and allowed to degenerate for a period of 7 days. In 3 experiments a single beta axons survived supplying tenuissimus, and in 2 experiments beta axons were among 4 or 5 surviving axons that supplied superficial lumbrical and abductor digiti quinti medius muscles. Motor endings identified as p1 plates were found in teased, silver preparations of all experimental muscles, a total of 35 such plates being located in 15 spindles. The plates were all supplied to bag1 fibres. The experiments show that if a spindle innervated by a beta axon is deprived of its gamma supply by degeneration the motor endings that remain intact are p1 plates.
D000818:Animals; D001369:Axons / Q000502:physiology* / Q000648:ultrastructure; D002415:Cats; D004558:Electric Stimulation; D005071:Evoked Potentials; D006614:Hindlimb / Q000294:innervation; D009045:Motor Endplate / Q000033:anatomy & histology / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology* / Q000648:ultrastructure; D009047:Motor Neurons, Gamma / Q000502:physiology; D009470:Muscle Spindles / Q000033:anatomy & histology / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D009410:Nerve Degeneration; D009431:Neural Conduction