[Impaired function of the sympatho-adrenal system in patients with esophageal and stomach cancer].
Patients with esophageal and gastric cancer show a decreased diurnal excretion of DOPA matched by a considerable drop in the urine levels of catecholamines and their main metabolites as compared with healthy subjects. This points to a severe inhibition of synthesis and metabolism of catecholamines at all stages. Tumor process progression is accompanied by an ever-increasing inhibition of sympatho-adrenal system function. Simultaneously, disorders develop in the functioning of the cholinergic structures of the nervous system.
D000311:Adrenal Glands / Q000503:physiopathology*; D000328:Adult; D002395:Catecholamines / Q000652:urine*; D002802:Cholinesterases / Q000097:blood; D004295:Dihydroxyphenylalanine / Q000652:urine; D004938:Esophageal Neoplasms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*
D002395:Catecholamines; D004295:Dihydroxyphenylalanine; D002802:Cholinesterases
Narushenie funktsii simpatoadrenalovoĭ sistemy u bol'nykh rakom pishchevoda i zheludka.