title: [Effect of T-activin on the production of immune interferon].
abstract: A study was made of the effect of T-activin on the biosynthesis of immune gamma-interferon. It was shown that in 27% of patients with chronic nonspecific pulmonary diseases, production of gamma-interferon by lymphocytes was substantially reduced during exacerbation of inflammatory process in the lungs. It was discovered that T-activin was not an interferon inductor but enhanced its synthesis in patients with a low capacity of producing immune interferon even at small doses of interferon inductor. The preparation does not produce any effect on this process in normal subjects and in patients showing the normal level of gamma-interferon. Thus T-activin can be used for stimulation of interferonogenesis.
mesh_terms: D000328:Adult; D004768:Enterotoxins / Q000494:pharmacology; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis*; D007978:Levamisole / Q000494:pharmacology; D008173:Lung Diseases, Obstructive / Q000276:immunology; D008875:Middle Aged; D010455:Peptides; D013268:Stimulation, Chemical; D013949:Thymus Extracts / Q000494:pharmacology*
chemical_list: D004768:Enterotoxins; D010455:Peptides; D013949:Thymus Extracts; D007978:Levamisole; C026066:enterotoxin A, Staphylococcal; D007371:Interferon-gamma; C036191:T-activin
vernacular_title: Deĭstvie T-aktivina na produktsiiu immunogo interferona.