Simultaneous inheritance and expression of classical haemophilia A and type IIA von Willebrand's disease.
A family is described in which the mother is a haemophilia carrier, the father has asymptomatic type IIA von Willebrand's disease, and their second son has simultaneously inherited both severe haemophilia and type IIA von Willebrand's disease. This is the first report of both diseases occurring simultaneously. The inheritance patterns and laboratory data on the family are presented and discussed.
D000941:Antigens / Q000032:analysis; D001780:Blood Coagulation Tests; D004586:Electrophoresis; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005260:Female; D006467:Hemophilia A / Q000150:complications / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D008970:Molecular Weight; D010375:Pedigree; D014842:von Willebrand Diseases / Q000150:complications / Q000235:genetics*; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII