title: Wide distribution of pH-dependent service of transport system ASC for both anionic and zwitterionic amino acids.
abstract: Criteria have been set up for recognizing the trait of interconvertibility of transport System ASC, whereby it operates in a deprotonated form to mediate the transport of zwitterionic amino acids and in a protonated form to transport anionic amino acids. This trait has been detected by each criterion applied, in all the tested occurrences of System ASC, as follows: the Ehrlich ascites tumor cell in suspension; a cultured variant thereof in monolayer; the Chinese hamster ovary cell CHO-K1 in monolayer; the pigeon red blood cell in suspension; and the human red blood cell in suspension. We conclude that this trait is a general feature of System ASC which may we may use provisionally in defining the system.
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002460:Cell Line; D010856:Columbidae; D006224:Cricetinae; D003412:Cricetulus; D003545:Cysteine / Q000031:analogs & derivatives* / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D051379:Mice; D018377:Neurotransmitter Agents; D010053:Ovary; D012964:Sodium / Q000494:pharmacology; D013912:Threonine / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D018377:Neurotransmitter Agents; D013912:Threonine; D012964:Sodium; D003545:Cysteine; C013461:cysteine sulfinic acid