title: Prostaglandins in human disease.
abstract: Disturbances in prostaglandin synthesis and/or metabolism have been associated with the expression of multiple symptoms in various human disease states. Pain, fever, inflammation, and diarrhea are general symptoms among several that occur in patients who overproduce prostaglandins. Treatment of patients with prostaglandin-related symptoms in specific disease states can be achieved with prostaglandin synthesis inhibitor drugs. Plasma and urine measurements of prostaglandins can be of use in the diagnosis and monitoring of treatment of specific human diseases where prostaglandin excess is causative of the disease symptoms.
mesh_terms: D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D002319:Cardiovascular System / Q000503:physiopathology; D002490:Central Nervous System / Q000503:physiopathology; D004064:Digestive System / Q000503:physiopathology; D005938:Glucocorticoids / Q000494:pharmacology; D006402:Hematologic Diseases / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology; D011448:Prostaglandin Antagonists / Q000494:pharmacology; D011453:Prostaglandins / Q000096:biosynthesis / Q000502:physiology* / Q000627:therapeutic use; D012098:Reproduction; D012137:Respiratory System / Q000503:physiopathology
chemical_list: D001095:Arachidonic Acids; D005938:Glucocorticoids; D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D016718:Arachidonic Acid