Focal hyperirritability of tissues is a clinical fact.
D001416:Back Pain / Q000209:etiology* / Q000628:therapy; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D008297:Male; D009135:Muscular Diseases / Q000150:complications / Q000175:diagnosis*; D009333:Neck; D010146:Pain / Q000209:etiology*; D012782:Shoulder