[Amino acid composition of proteoglycan protein of human articular cartilage in normal conditions and in degeneration].
Proteoglycan protein of human articular cartilage is found to contain a considerable amount of leucine, proline, glutaminic acid and glycine. The amino acid composition of various proteoglycan fractions differs in the methionine content. Proteoglycan protein from the degeneratively changed cartilage contains a less amount of lysine and serine. It is supposed that the found changes may be induced by the atypical synthesis of the proteoglycan protein shaft by chondrocytes under the cartilage degeneration.
D000596:Amino Acids / Q000032:analysis*; D002357:Cartilage Diseases / Q000378:metabolism / Q000473:pathology; D002358:Cartilage, Articular / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008239:Lysine / Q000032:analysis; D011509:Proteoglycans / Q000032:analysis*; D012694:Serine / Q000032:analysis
D000596:Amino Acids; D011509:Proteoglycans; D012694:Serine; D008239:Lysine
Aminokislotnyĭ sostav belka proteoglikanov sustavnogo khriashcha cheloveka v norme i pri degeneratsii.