Urinary adrenaline concentrations during 10 days of smoking abstinence.
Urinary adrenaline concentrations were measured in 17 subjects during 10 days of cigarette abstinence. Adrenaline concentrations dropped significantly in the first 3 days of cigarette withdrawal. This was followed by a significant rise. More subjects showed a U-shaped function of adrenaline over time than would be expected by chance. The evidence suggests that the drop in urinary adrenaline concentration following cigarette withdrawal does not merely constitute a return to a non-smoking state, but includes an element of rebound resulting from loss of a component of smoking, probably nicotine, to which adaptation has occurred.
D000328:Adult; D004837:Epinephrine / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D012907:Smoking; D013375:Substance Withdrawal Syndrome / Q000652:urine*; D013997:Time Factors
D004837:Epinephrine