Factor VIII-related antigen in Kaposi's sarcoma in young homosexual men.
This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.
D000941:Antigens / Q000032:analysis*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology*; D006716:Homosexuality; D006801:Humans; D008297:Male; D012514:Sarcoma, Kaposi / Q000276:immunology* / Q000473:pathology; D012878:Skin Neoplasms / Q000276:immunology* / Q000473:pathology; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII