Whole-body elemental composition in patients with renal failure and after transplantation studied using total-body neutron-activation analysis.
Whole body elemental composition in seventy-five patients with either renal failure or a kidney transplant was measured by neutron-activation analysis and whole-body counting. Comparison was made with expected normal values and with a control group; between undialysed, dialysed and transplanted patients; and between those receiving dialysis treatment for various periods. A frequent finding was low body calcium, reflecting the prevalence of renal osteodystrophy. Sodium and chlorine were increased in undialysed patients, a consequence of their renal disease. Patients with transplanted kidneys had reduced amounts of most elements, indicating decreased lean body mass, but increased body weight, probably due to excess fat.
D001823:Body Composition; D001834:Body Water / Q000032:analysis; D002118:Calcium / Q000032:analysis; D002713:Chlorine / Q000032:analysis; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism*; D016030:Kidney Transplantation; D008297:Male; D009501:Neutron Activation Analysis; D010101:Oxygen Consumption; D011188:Potassium / Q000032:analysis; D006435:Renal Dialysis; D012964:Sodium / Q000032:analysis
D002713:Chlorine; D012964:Sodium; D011188:Potassium; D002118:Calcium