title: In vitro incorporation of (U-C14)-glucose and (1-C14)-sodium acetate in peripheral nerves of malnourished young rhesus monkeys.
abstract: The effect of protein calorie malnutrition (PCM) on synthesis of lipids in peripheral nerves was studied by in vitro incorporation of (U-C14)-glucose and (1-C14)-sodium acetate. Ulnar and tibial nerves obtained from five young rhesus monkeys with PCM, five rehabilitated monkeys, and five control monkeys were incubated for 2 h with the radioactive precursors. Uptake of both radioactive precursors in whole peripheral nerves as well as myelin marker lipids was significantly decreased in animals with PCM. However, uptake returned to normal in rehabilitated monkeys.
mesh_terms: D000085:Acetates / Q000378:metabolism*; D019342:Acetic Acid; D000818:Animals; D000830:Animals, Laboratory; D002250:Carbon Radioisotopes; D002554:Cerebrosides / Q000096:biosynthesis; D002784:Cholesterol / Q000096:biosynthesis; D005230:Fatty Acids, Nonesterified / Q000096:biosynthesis; D005947:Glucose / Q000378:metabolism*; D066298:In Vitro Techniques; D008055:Lipids / Q000096:biosynthesis*; D008251:Macaca; D008253:Macaca mulatta; D008297:Male; D008992:Monkey Diseases / Q000378:metabolism*; D010525:Peripheral Nerves / Q000378:metabolism*; D011502:Protein-Energy Malnutrition / Q000378:metabolism / Q000662:veterinary*; D014280:Triglycerides / Q000096:biosynthesis
chemical_list: D000085:Acetates; D002250:Carbon Radioisotopes; D002554:Cerebrosides; D005230:Fatty Acids, Nonesterified; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol; D005947:Glucose; D019342:Acetic Acid