Macular skin lesion and monoclonal lymphoplasmacytoid infiltrates. Occurrence in primary Waldenström's macroglobulinemia.
Macular skin lesions and extensive, heavy lymphoplasmacytoid cell infiltrates of the dermis were observed in a patient with primary IgM-kappa Waldenström's macroglobulinemia. Direct immunofluorescent microscopy on tissue sections disclosed that the lymphoplasmacytoid cells had a monoclonal IgM-kappa origin.
D000368:Aged; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D010950:Plasma Cells / Q000276:immunology / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology / Q000473:pathology*
D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains