title: Erythema elevatum diutinum treated with niacinamide and tetracycline.
abstract: A 60-year-old woman with recurrent papular and vesiculobullous lesions of erythema elevatum diutinum responded to treatment with 100 mg of oral niacinamide three times a day and 250 mg of tetracycline hydrochloride four times a day. Prior therapy with 2.5 mg of dexamethasone daily and 1.0 g of erythromycin daily had been unsuccessful. After four weeks, tetracycline therapy was discontinued, and niacinamide alone sufficed to suppress the disorder. Recurrent lesions developed whenever niacinamide therapy was stopped.
mesh_terms: D004359:Drug Therapy, Combination; D004890:Erythema / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009536:Niacinamide / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D013752:Tetracycline / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009536:Niacinamide; D013752:Tetracycline