[Stimulating action of human serum on the incorporation of tritiated thymidine in human lymphocytes activated by lectins: demonstration of the GH-dependency and its limitations].
Using thymidine uptake by activated human lymphocytes to measure the growth-stimulating activity of human serum, the authors demonstrate that thymidine activity was significantly correlated (p less than 0.001) with GH levels. r = 0.729 when GH values are below 3.5 ng/ml, r = 0.509 when GH values are below 8 ng/ml and r = 0.337 for all of the patients. Low levels of GH are sufficient for the generation of this activity.
D000293:Adolescent; D001790:Blood Physiological Phenomena; D002648:Child; D005260:Female; D013006:Growth Hormone / Q000097:blood / Q000502:physiology*; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D013936:Thymidine / Q000097:blood*; D014316:Tritium
D037102:Lectins; D014316:Tritium; D013006:Growth Hormone; D013936:Thymidine
Activité stimulante du sérum humain sur l'incorporation de thymidine tritiée dans le lymphocyte humain activé par les lectines: mise en évidence de la GH-dépendance et de ses limies.