Total body calcium mass in primary hyperparathyroidism and long-term changes.
The total body calcium mass of patients with primary hyperparathyroidism was measured by whole-body neutron activation analysis. Among 14 untreated patients, the calcium mass was significantly subnormal in 2. Long-term follow-up in 4 unoperated patients showed that the calcium mass remained unchanged in 3; in the 4th patient, parathyroidectomy was carried out after the 18th month of follow-up. Her total body calcium fell by 16% before operation, but was nearly regained in the following 3 years. In 1 patient followed for 32 months after parathyroidectomy, the calcium mass remained unchanged. After a follow-up in 4 additional patients for an average of 15 months, the calcium mass remained unchanged in 3, whereas the 4th showed a significant decrease 12 months after the first measurement.
D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D002136:Calcium, Dietary / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009501:Neutron Activation Analysis; D013997:Time Factors
D002136:Calcium, Dietary; D002118:Calcium