Increase of sialyltransferase activity in the serum and liver of inflamed rats.
Induction of inflammation by turpentine injection caused 1.5-2-fold increase of both sialyl- and galactosyltransferase activity in liver homogenates. The effect was apparent after 12 h of turpentine treatment. Serum sialyltransferase activity started to increase in the inflamed rats after 18 h, reaching a maximum of 4-fold at 48 h. In contrast, galactosyltransferase activity in serum showed no significant increase. The coordinated and temporal increase of sialyltransferase activity in liver and serum suggest involvement of a specific mechanism for the preferential release of this enzyme into serum.
D000818:Animals; D005700:Galactosyltransferases / Q000378:metabolism*; D007249:Inflammation / Q000139:chemically induced / Q000201:enzymology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D012799:Sialyltransferases / Q000097:blood / Q000378:metabolism*; D014166:Transferases / Q000378:metabolism*; D014425:Turpentine
D014166:Transferases; D005700:Galactosyltransferases; D012799:Sialyltransferases; D014425:Turpentine