title: Duodenal diverticula occurring in a family--chance or inheritance?
abstract: The incidence, aetiology and possible inheritance of duodenal diverticula remain controversial. These aspects are discussed through the presentation of a family, in which duodenal diverticula occurred in a man and his two sons. To the best of our knowledge, this is the first such family documented in the medical literature. This familial occurrence may be attributed solely to the high incidence of duodenal diverticula in the general population (set by various authors at up to 14.2%), and, therefore, of no hereditary significance at all. We believe a screening study of the families of individuals with proven duodenal diverticula is most desirable, for it could shed light upon the controversial questions of incidence, aetiology, and inheritance patterns of duodenal diverticula.
mesh_terms: D000368:Aged; D004240:Diverticulum / Q000235:genetics*; D004378:Duodenal Diseases / Q000235:genetics*; D006801:Humans; D008297:Male