title: The main determinants of nitrogen balance during total parenteral nutrition in critically ill injured patients.
abstract: Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26 +/- 0.12 (SD) g X kg-1), but improved consistently during treatment. Nitrogen intake proved to be the major determinant of a positive, or less negative, nitrogen balance, only secondarily followed by total energy intake corrected to predicted basal energy expenditure, according to multiple regression analysis. The amount of non-protein calories and the non-protein calorie to nitrogen ratio appeared to have little significance on nitrogen balance, when corrected for the two former variables.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism*; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total; D012189:Retrospective Studies; D014947:Wounds and Injuries / Q000378:metabolism*
chemical_list: D009584:Nitrogen