Chromosomal mutation that affects excretion of hemolysin in Escherichia coli.
Two types of mutants unable to excrete hemolysin were obtained when E. coli 5K carrying the multicopy hemolytic recombinant plasmid pANN202-312 was mutagenized with Mu d1. One type is altered in the plasmid hly-specific gene, hlyBb, but the other is caused by an insertion of Mu d1 into a chromosomal locus.
D049933:Aminocoumarins; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002876:Chromosomes, Bacterial / Q000502:physiology*; D003374:Coumarins / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D006460:Hemolysin Proteins / Q000378:metabolism*; D009154:Mutation; D010957:Plasmids; D014169:Transformation, Bacterial; D001616:beta-Galactosidase / Q000235:genetics
D049933:Aminocoumarins; D000900:Anti-Bacterial Agents; D003374:Coumarins; D006460:Hemolysin Proteins; D001616:beta-Galactosidase; C004628:coumermycin