Hemangioendothelioma of bone. A case report with massive tissular necrosis.
Hemangioendothelioma or histiocytoid hemangioma of bone is a low grade tumor, which may be a quite indolent and controlable lesion, even in the rare case it develops distant metastasis. Our case presents features of such lesion by light microscopy and with a peroxidase-antiperoxidase technique for Factor VIII related antigen, but it exhibits an unusual extensive tissular necrosis. Necrosis does not seems to make worse the usual course, after six years and ten months of conservative surgical treatment and radiation therapy.
D000328:Adult; D000941:Antigens / Q000032:analysis; D001859:Bone Neoplasms / Q000473:pathology*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D006801:Humans; D008297:Male; D009336:Necrosis; D012512:Sarcoma, Ewing / Q000032:analysis / Q000473:pathology*; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII