Effect of tissue selection on melanization of MI hamster melanoma.
Selection of the most melanized tissue of the slightly melanotic MI melanoma in hamster resulted in an origin of a new highly melanotic tumor line. It differed from the parental MI melanoma in the 5-fold higher melanin content, but its tyrosinase activity, growth rate and histological structure remained unchanged. Selection of the least melanotic tissue of the MI melanoma did not give positive results.
D000818:Animals; D006224:Cricetinae; D008297:Male; D008543:Melanins / Q000378:metabolism*; D008545:Melanoma / Q000378:metabolism / Q000473:pathology*; D008647:Mesocricetus; D014442:Monophenol Monooxygenase / Q000032:analysis; D009368:Neoplasm Transplantation; D010858:Pigmentation
D008543:Melanins; D014442:Monophenol Monooxygenase