Growth hormone and endothelial function during exercise in diabetics with and without retinopathy.
Changes in plasma growth hormone (GH), factor VIII related antigen (VIIIR:Ag), and plasminogen activator activity (PAA) during exercise were evaluated in 50 insulin-dependent diabetics. In patients with a short to moderately long duration of diabetes (5-19 years, mean 11), GH increased only in those with retinopathy. VIIIR:Ag and PAA increased most pronouncedly in retinopathy patients as well. In diabetics with long duration of the disease (21-49 years, mean 35), GH, VIIIR:Ag and PAA increased almost equally in those with and without retinopathy.
D000328:Adult; D000941:Antigens / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000097:blood* / Q000503:physiopathology; D004727:Endothelium / Q000503:physiopathology*; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D010960:Plasminogen Activators / Q000097:blood; D014841:von Willebrand Factor
D000941:Antigens; D014841:von Willebrand Factor; D005169:Factor VIII; D013006:Growth Hormone; D010960:Plasminogen Activators