[Biological properties of a synthetic sequence (10-24) of the gamma chain from sub-unit A of cholera toxin].
The biological activity of a synthetic fragment of choleric toxin. gamma Chain A subunit, was studied in vivo. This pentadecapeptide (10-24) was synthesized by solid phase method and finally purified by HPLC. Associated with the B subunit, the peptide inhibits the tissue water loss induced by commercial choleric toxin.
D000595:Amino Acid Sequence; D000818:Animals; D002772:Cholera Toxin / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005779:Immunodiffusion; D007422:Intestines / Q000187:drug effects; D046911:Macromolecular Substances; D010446:Peptide Fragments / Q000138:chemical synthesis* / Q000494:pharmacology; D011817:Rabbits
D046911:Macromolecular Substances; D010446:Peptide Fragments; D002772:Cholera Toxin
Propriétés biologiques d'une séquence synthétique (10-24) de la chaîne gamma de la sous-unité A de la toxine cholérique.