title: [Systemic arterial hypertension caused by discharge of catecholamines following ligation of ductus arteriosus].
abstract: A case of severe systemic hypertension due to catecholamines discharge after ligation of a large patent ductus arteriosus in an 8 months old child is reported. The blood pressure was corrected by the association of alpha- and betablocker drugs which were withdrawn on the 15th post-operative day without recurrence. Transient increases in blood pressure are quite common after closure of a patent ductus arteriosus with a large shunt. Persistent hypertension greater than 160/110 mmHg is rare. It always regresses but may sometimes cause complications. Hyperactivity of the sympathetic nervous system has already been suggested as a possible cause. Massive discharge of catecholamines and the spectacular effect of the association of alpha- and betablocker therapy, reported here apparently for the first time, provide additional evidence in favour of this hypothesis.
mesh_terms: D002395:Catecholamines / Q000378:metabolism*; D004374:Ductus Arteriosus, Patent / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000378:metabolism; D007223:Infant; D008026:Ligation / Q000009:adverse effects; D008297:Male
chemical_list: D002395:Catecholamines
vernacular_title: Hypertension artérielle systémique par décharge de catécholamines après ligature d'un canal artériel.