title: [Patterns in the distribution of GPD- alleles in Azerbaijan. II. Population genetic structure of 3 villages in the Shekii district].
abstract: In order to clear out the role of genetico-automatic processes in Gd- distribution the investigation of population structure of three settlements in the Shekii district was carried out. Sex and age ratios and the average number of living children on one marriage (> 5.7) bear evidence of expanded reproduction in this population. The high frequency of endogamous marriages (approximately 80%) and 14 cases of consaguinous marriage for 183 analysed pedigree were revealed. The allele frequencies in 6 polymorphic systems were determined: ABO, Rh, Hp, PGM, Gc and AP; in the first three there were found out the statistically significant differences in alleles' frequency between subpopulations, but not in the last three systems. The differentiation type of allele frequency in all 6 loci was similar in subpopulations. The inbreeding coefficient fst determined upon the differentiation of the gene frequency at three loci is 0.00583.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000483:Alleles; D001382:Azerbaijan; D002648:Child; D003241:Consanguinity; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D014644:Genetic Variation; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006801:Humans; D008297:Male; D012737:Sex Factors
chemical_list: D005819:Genetic Markers
vernacular_title: Zakonomernosti rasprostraneniia alleleĭ Gd- v Azerbrĭdzhane. Soobshchenie II. Populiatsionno-geneticheskaia struktura trekh sel Shekinoskogo raĭona.