Rapid antimicrobial susceptibility testing of Gram-negative clinical isolates with the AutoMicrobic system.
Comparisons of the antimicrobial susceptibility patterns of clinical isolates of the family Enterobacteriaceae and Pseudomonas aeruginosa were made by using Kirby-Bauer disk diffusion, the MicroMedia system broth microdilution, and the AutoMicrobic system. The Kirby-Bauer system compared favorably with the MicroMedia system (95% essential correlation with 90% complete agreement). The AutoMicrobic system also compared favorably with both the Kirby-Bauer system (93% essential correlation with 87% complete agreement) and the MicroMedia system (97% essential correlation with 85% complete agreement). These data indicate that the AutoMicrobic system results are comparable to those of the MicroMedia and the Kirby-Bauer systems. Furthermore, the AutoMicrobic system offers a more rapid system (6 to 10 h), than the traditional systems, without sacrificing accuracy (16 to 24 h).
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects*; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D011933:Reagent Kits, Diagnostic
D000900:Anti-Bacterial Agents; D011933:Reagent Kits, Diagnostic