In vitro effect of the slime of Pseudomonas aeruginosa on the function of human polymorphonuclear neutrophils.
The slime of Pseudomonas aeruginosa markedly impaired the in vitro motility, endocytosis, and phagosome formation of normal human polymorphonuclear neutrophils. This profound impairment of neutrophils, although without alteration of their viability, may contribute to the virulence of this microorganism.
D002634:Chemotaxis, Leukocyte; D004705:Endocytosis; D006801:Humans; D008854:Microscopy, Electron; D009504:Neutrophils / Q000382:microbiology*; D010587:Phagocytosis; D011550:Pseudomonas aeruginosa / Q000472:pathogenicity*