[The treatment of lumbosciatica by intra-discal injection of proteolytic enzymes (nucleolysis). 80 cases (author's transl)].
Proteolytic enzymes originated from carica papaya, injected extra durally in the lumbar intervertebral disc of 80 patients suffering from intractable root pain due to herniated discs, led to 85% of satisfactory results as far as root pain is concerned. Strong motivation and appropriate deals with residual lumbar pain which was absent or kept under control in 85% of all cases. Surgery can be successfully carried out after nucleolysis, when an adherent root and/or an extruded fragment is responsible of the failure.
D000328:Adult; D000368:Aged; D001416:Back Pain / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007267:Injections; D007403:Intervertebral Disc; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D010447:Peptide Hydrolases / Q000008:administration & dosage / Q000627:therapeutic use*; D012585:Sciatica / Q000188:drug therapy* / Q000601:surgery
D010447:Peptide Hydrolases
Traitement des lombo-sciatiques par injection intra-discale d'enzymes protéolytiques (nucléolyse). 80 observations.