title: [Instability of serum 17 beta-hydroxysteroid dehydrogenases of placental origin].
abstract: The stabilization by glycerol of the serum estradiol 17 beta dehydrogenase has been investigated here in terms of time and temperature. The protected enzyme is stable for a month at least at --20 degrees C. Its activity reaches a maximum at 60 degrees C. In another connection, effect of reduced glutathione, of N. acetyl-cysteine and of various mineral ions on the enzymic conversion has been studied.
mesh_terms: D015067:17-Hydroxysteroid Dehydrogenases / Q000097:blood*; D004355:Drug Stability; D005260:Female; D005978:Glutathione / Q000494:pharmacology; D005990:Glycerol / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D013696:Temperature; D013997:Time Factors
chemical_list: D015067:17-Hydroxysteroid Dehydrogenases; D005978:Glutathione; D005990:Glycerol
vernacular_title: Sur l'instabilité de la 17 beta-hydroxystéroïde-déshydrogénase sérique d'origine placentaire.