Inner ear and renal diseases.
Certain conditions (Alport's syndrome, kidney transplantation, dialysis) are followed by a progressive inner ear hearing loss. On the other hand, pharmacological substances that act on the transport mechanisms of the tubular epithelium may also produce inner ear disturbance. Experimental data on the possible pathomechanisms are discussed in reference to results reported in the literature.
D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006311:Hearing Disorders / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000473:pathology / Q000628:therapy; D007678:Kidney Glomerulus / Q000648:ultrastructure; D016030:Kidney Transplantation; D007759:Labyrinth Diseases / Q000209:etiology* / Q000473:pathology; D008854:Microscopy, Electron; D008875:Middle Aged; D009394:Nephritis, Hereditary / Q000150:complications / Q000473:pathology; D011817:Rabbits; D006435:Renal Dialysis / Q000009:adverse effects; D013316:Stria Vascularis / Q000648:ultrastructure