Factors influencing disproportionate replication of the ribosomal RNA cistrons in Drosophila melanogaster.
This report describes studies of the compensatory response employing D. melanogaster stocks that bear cloned-X chromosomes derived from laboratory populations of strains Oregon R and Canton S. We find that modification of the autosomal background in either the female or the XY male parent influences the expression of the compensatory response by X chromosomes derived from the Canton S population, whereas Oregon R isolates are unresponsive to these effects. We have also studied compensatory replication in X/O larvae produced from cloned-X derivatives of both Canton S and Oregon R. Canton S larval compensation exceeds that of the adult, whereas in Oregon R the converse is true. We have concluded that both X chromosomal and autosomal factors affect the expression and magnitude of the compensatory response.
D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D004261:DNA Replication; D004275:DNA, Ribosomal; D004303:Dosage Compensation, Genetic; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005786:Gene Expression Regulation; D005796:Genes; D005838:Genotype; D008297:Male; D012335:RNA, Ribosomal / Q000096:biosynthesis*; D014960:X Chromosome
D004275:DNA, Ribosomal; D012335:RNA, Ribosomal; D004247:DNA