[Bacteriological and architectural studies of infected stones].
The stones associated with urinary tract infection were cultured using a method to distinguish between surface contamination and bacteria within the stone. Twenty three of 30 stones (77%) were infected mainly by Proteus mirabilis or Pseudomonas aeruginosa and most were composed of struvite and/or apatite. Most oxalate and uric acid stones were sterile; occasionally the stones with positive culture had a non-urea-splitting bacteria and these were thought to have been infected secondarily. Some infected stones were studied by light microscopy scanning election microscopy and transmission electron microscopy. We found many rods in the interstices of crystals of struvite and apatite extensively from the nucleus to peripheral layers. These findings are important in the prevention and treatment of infection stones.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001031:Apatites / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008274:Magnesium / Q000032:analysis; D017616:Magnesium Compounds; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000032:analysis; D011513:Proteus mirabilis / Q000302:isolation & purification; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D000069877:Struvite; D014545:Urinary Calculi / Q000150:complications / Q000378:metabolism* / Q000382:microbiology; D014552:Urinary Tract Infections / Q000150:complications*
D001031:Apatites; D017616:Magnesium Compounds; D010710:Phosphates; D000069877:Struvite; D008274:Magnesium