Glucose-6-phosphate dehydrogenase deficiency and Rh factor.
The incidence of carriers of the Gd(-) gene and the Rh(+) and Rh(-) alleles was studied in 10 342 Bulgarian individuals living in 306 villages in 5 districts at different altitudes above the sea level. The results showed that the presence of the Gd(-) gene is considerably less frequent in Rh(-) than in Rh(+) individuals. In populations with a high frequency of G6PD deficiency the frequency of the Rh(-) allele is low.
D000531:Altitude; D002031:Bulgaria; D005260:Female; D005828:Genetics, Population; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006801:Humans; D008288:Malaria / Q000453:epidemiology; D008297:Male; D011159:Population Surveillance; D012204:Rh-Hr Blood-Group System; D012424:Rural Population; D012641:Selection, Genetic
D012204:Rh-Hr Blood-Group System