The selection of antigens for the diagnosis, prognosis and evolutive study of parasitic diseases.
The hypothesis is set forth that schizodeme (kDNA) typing of Trypanosoma cruzi, and possible other parasites, may be used to resolve the problem associated with the protean clinical manifestations of the disease. kDNA typing of T. cruzi clones may turn out to be useful in: (1) diagnosis; (2) prognosis; (3) production of species (generic) vaccines; (4) the study of autoimmunity. We recommend that an international culture bank of schizodeme-type T. cruzi be established.
D000818:Animals; D000941:Antigens / Q000032:analysis* / Q000276:immunology; D014355:Chagas Disease / Q000175:diagnosis* / Q000276:immunology / Q000469:parasitology; D004247:DNA / Q000032:analysis*; D006801:Humans; D051379:Mice; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology; D014349:Trypanosoma cruzi / Q000145:classification* / Q000235:genetics / Q000276:immunology; D014611:Vaccination; D014612:Vaccines / Q000276:immunology
D000941:Antigens; D014612:Vaccines; D004247:DNA