Elliptocytosis preceding myelofibrosis in a patient with polycythemia vera.
A patient with polycythemia vera showed marked elliptocytosis in the peripheral blood, 2 years after the diagnosis was established. 4 years later on, the patient developed myelofibrosis. The significance of elliptocytosis, which appears during the course of polycythemia vera, as an early indicator for the development of myelofibrosis is discussed.
D000368:Aged; D001803:Blood Transfusion; D001815:Bloodletting; D004612:Elliptocytosis, Hereditary / Q000150:complications*; D004913:Erythrocytes, Abnormal / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D011087:Polycythemia Vera / Q000150:complications* / Q000628:therapy; D055728:Primary Myelofibrosis / Q000209:etiology* / Q000628:therapy