N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors*; D000818:Animals; D002417:Cattle; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology; D004376:Galactitol / Q000378:metabolism; D007546:Isoquinolines / Q000494:pharmacology; D007908:Lens, Crystalline / Q000201:enzymology; D009281:Naphthalenes / Q000494:pharmacology*; D051381:Rats; D013012:Sorbitol / Q000097:blood; D013401:Sugar Alcohol Dehydrogenases / Q000037:antagonists & inhibitors*
D007546:Isoquinolines; D009281:Naphthalenes; C040550:tolrestat; D004376:Galactitol; D013012:Sorbitol; C016212:alrestatin; D013401:Sugar Alcohol Dehydrogenases; D000449:Aldehyde Reductase