Alloantibody to a sex-influenced esterase in rats (Rattus norvegicus).
An antiserum to a serum protein from female ACI rats was produced in DONRYU rats by alloimmunization. The serum protein reacting with this antiserum was shown to be a sex-influenced esterase which is identified by zymogram techniques. Evidence for this is as follows: this protein migrated in the albumin region on agarose gel immunoelectrophoresis and was not present in sera from mature males; all rats possessing the protein were sex-influenced esterase in sera specifically disappeared after treatment with this antiserum. The attempt in ACI rats to produce antiserum to the esterases from DONRYU rats was unsuccessful.
D000818:Animals; D004950:Esterases / Q000235:genetics / Q000276:immunology*; D005260:Female; D007114:Immunization / Q000662:veterinary; D005779:Immunodiffusion / Q000662:veterinary; D007122:Immunoelectrophoresis; D007136:Immunoglobulins / Q000032:analysis*; D007518:Isoantibodies / Q000032:analysis*; D008297:Male; D051381:Rats / Q000276:immunology*; D011912:Rats, Inbred ACI / Q000276:immunology; D011919:Rats, Inbred Strains / Q000235:genetics; D012737:Sex Factors
D007136:Immunoglobulins; D007518:Isoantibodies; D004950:Esterases