Elastin accumulation in the chick aorta: effect of 6-hydroxydopamine and deoxycorticosterone acetate.
The net accumulation of aorta elastin in the chick was estimated from day 1 to 14, post-hatching. Increased elastin accumulation was coincident with the elevation in blood pressure observed for this period. Further deoxycorticosterone acetate plus dietary NaCl also caused stimulation of protein synthesis in aorta. In contrast, aorta protein synthesis and net elastin accumulation appeared to be decreased in chicks given 6-hydroxydopamine.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D001794:Blood Pressure / Q000187:drug effects; D002645:Chickens; D003900:Desoxycorticosterone / Q000494:pharmacology*; D004032:Diet; D004549:Elastin / Q000378:metabolism*; D006892:Hydroxydopamines / Q000494:pharmacology*; D008297:Male; D009124:Muscle Proteins / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000378:metabolism*; D016627:Oxidopamine; D014633:Valine / Q000378:metabolism
D006892:Hydroxydopamines; D009124:Muscle Proteins; D003900:Desoxycorticosterone; D016627:Oxidopamine; D004549:Elastin; D014633:Valine