[Effects of central administration of glucocorticoids on evoked electric activity of the hippocampus in mice].
The effect of central intraventricular administration (1 microgram) of corticosterone or dexamethasone on evoked electrical activity of dorsal hippocampus was analyzed in anaesthetized BALB/c mice. Corticosterone produced an important decrease in amplitude of the population spike activity elicited in CA1 field through commissural stimulation as well as through stimulation of the perforant path. In the same conditions, dexamethasone produced only a slight and brief effect.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D003345:Corticosterone / Q000494:pharmacology; D003907:Dexamethasone / Q000494:pharmacology; D005071:Evoked Potentials / Q000187:drug effects; D006624:Hippocampus / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C
D000305:Adrenal Cortex Hormones; D003907:Dexamethasone; D003345:Corticosterone
Effets de l'administration centrale de glucocorticoïdes sur l'activité électrique évoquée de l'hippocampe chez la Souris.