Brain calcification in severely stressed neonates receiving parenteral calcium.
Morphologic evidence for calcium salts within the brains of severely stressed neonates at autopsy correlated to the mean daily parenteral dose of calcium gluconate (P less than 0.01). Survival analysis indicated that parenteral administration of calcium contributed a negative effect to predicted survival (P less than 0.05).
D001927:Brain Diseases / Q000139:chemically induced* / Q000473:pathology; D002114:Calcinosis / Q000139:chemically induced* / Q000473:pathology; D002125:Calcium Gluconate / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005942:Gluconates / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy*; D008297:Male; D010288:Parenteral Nutrition
D005942:Gluconates; D002125:Calcium Gluconate