Susceptibility of hepatitis B virus to disinfectants or heat.
Using direct chimpanzee inoculation as an assay method, we tested the abilities of the following chemical or physical treatments to inactivate hepatitis B virus in human plasma: 1% aqueous glutaraldehyde at 24 degrees C for 5 min, 0.1% aqueous glutaraldehyde at 24 degrees C for 5 min, 80% ethyl alcohol at 11 degrees C for 2 min, and heat at 98 degrees C for 2 min. All treatments were shown to be effective, indicating that the resistance level of the hepatitis B virus is not extreme.
D000447:Aldehydes; D000818:Animals; D004202:Disinfectants; D000431:Ethanol; D005260:Female; D005976:Glutaral; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000254:growth & development*; D006358:Hot Temperature; D008297:Male; D002679:Pan troglodytes
D000447:Aldehydes; D004202:Disinfectants; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D000431:Ethanol; D005976:Glutaral