title: Mutagenic effects of aflatoxin B-1 and G-1 on the Egyptian cotton leaf-worm, Spodoptera littoralis (Boisd.).
abstract: The aim of this study was to test infertility of the Egyptian cotton leaf-worm, Spodoptera littoralis. Three concentrations, 0.8, 1.6 and 2.0 micrograms/larva of aflatoxin B-1 and G-1 were applied to the final instar of the larval period. Both B-1 and G-1 induced mutagenic effects on spermatogenesis and morphogenesis which consequently reflected in infertility of Spodoptera littoralis. The phenomenon of mutagenicity was more obvious in larvae treated with G-1 rather than in those treated with B-1. The two analogues were also capable of inducing malformations in sperms. These abnormalities were transmitted to and inherited by the progeny.
mesh_terms: D016604:Aflatoxin B1; D000348:Aflatoxins / Q000494:pharmacology*; D000818:Animals; D007814:Larva / Q000187:drug effects; D007915:Lepidoptera / Q000187:drug effects*; D008297:Male; D009036:Moths / Q000187:drug effects* / Q000235:genetics; D009153:Mutagens; D009154:Mutation; D013090:Spermatocytes / Q000187:drug effects
chemical_list: D000348:Aflatoxins; D009153:Mutagens; C027955:aflatoxin G1; D016604:Aflatoxin B1