The effect of dithiothreitol on the LW antigen.
Dithiothreitol (DTT) has been found to destroy the integrity of the LW antigen. This may pose a problem when DTT is used to differentiate IgM from IgG anti-LW, or may be used as an aid in the identification of anti-LW.
D000937:Antigen-Antibody Reactions; D004229:Dithiothreitol / Q000494:pharmacology*; D006801:Humans; D011487:Protein Conformation / Q000187:drug effects; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D012204:Rh-Hr Blood-Group System; D004229:Dithiothreitol