Aspergillic acids produced by mixed cultures of Aspergillus flavus and Aspergillus nidulans.
A mixed culture of Aspergillus nidulans (GH79) and Aspergillus flavus (CMI 91019B) produced two antibiotics, designated VI and VII, which were not elaborated when either fungus was grown alone. Chemical and spectroscopic analysis of VI, the major component, indicated that this compound was identical to hydroxyaspergillic acid. The minor component, VII, was produced in too low a yield for its identity to be established. However, partial characterization suggests that this antibiotic also belongs to the aspergillic acid group of mycotoxins.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001231:Aspergillus flavus / Q000378:metabolism*; D001233:Aspergillus nidulans / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D013058:Mass Spectrometry; D011719:Pyrazines / Q000096:biosynthesis
D000900:Anti-Bacterial Agents; D011719:Pyrazines; C004524:aspergillic acid; C041607:1-hydroxy-6-(1-hydroxy-1-methylpropyl)-3-(2-methylpropyl)-2(1H)-pyrazinone