Management of lithium intoxication.
Lithium toxicity is usually insidious in onset and presents with a wide spectrum of clinical symptoms. Symptoms vary from mild lethargy to seizures and coma. Although mild to moderate intoxication can be managed with intravenous saline, cases not responding or severe cases should be treated by hemodialysis. Iatrogenic fluid and electrolyte disorders often complicate therapy.
D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy; D003128:Coma / Q000139:chemically induced; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D008094:Lithium / Q000506:poisoning* / Q000627:therapeutic use; D016651:Lithium Carbonate; D006435:Renal Dialysis; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use*; D012640:Seizures / Q000139:chemically induced; D012965:Sodium Chloride / Q000627:therapeutic use*
D012462:Saline Solution, Hypertonic; D016651:Lithium Carbonate; D012965:Sodium Chloride; D008094:Lithium