title: The effects of porcine follicular fluid in the postcastration rise of gonadotropins in the rabbit.
abstract: The effects of repeated administration of porcine follicular fluid (PFF) on the follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels after castration were studied in rabbits. Steroid-free dextran-charcoal extracted PFF was administered to male and female adult rabbits at 0800 and 1600 h for four days immediately following castration. Serum levels of FSH and LH were measured before, during and after the PFF administration and compared to controls. A significant increase in FSH and LH was observed within 24 h following castration in the controls. In the PFF-treated group, a clear suppression of serum FSH levels was observed during PFF administration in both males and females. FSH concentrations returned to the control levels within 24 h after PFF withdrawal. Even through LH levels showed no differences during PFF injection, compared to controls, a significant increase was observed following discontinuation of PFF administration.
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000502:physiology*; D002369:Castration; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007265:Inhibins / Q000502:physiology; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D006080:Ovarian Follicle / Q000502:physiology*; D011817:Rabbits; D011863:Radioimmunoassay; D012737:Sex Factors; D013552:Swine
chemical_list: D007265:Inhibins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone