Intranuclear inclusions in hypothalamic neurons: a study in the ageing hamster.
Intranuclear inclusions have been observed in a wide variety of locations throughout the nervous system. In the present work we have studied the inclusions that appear within the nucleus of non-secretory neurons from both paraventricular and supraoptic nuclei of the hypothalamus of the ageing hamster. We described four morphological types, namely, micro-filamentous, crystalloid, circular and capsuled inclusions. Their relationships with both the nuclear membrane and the nucleolus are discussed in the light of their ultrastructural features.
D000375:Aging; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D006224:Cricetinae; D003599:Cytoskeleton / Q000648:ultrastructure*; D005260:Female; D005976:Glutaral; D007031:Hypothalamus / Q000254:growth & development* / Q000648:ultrastructure; D008297:Male; D009474:Neurons / Q000648:ultrastructure*
D005976:Glutaral