title: Relationship of plasma level and pharmacological activity of methadone.
mesh_terms: D000818:Animals; D001711:Biotransformation / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008691:Methadone / Q000097:blood* / Q000494:pharmacology; D009619:Nociceptors / Q000187:drug effects*; D009293:Opioid-Related Disorders / Q000097:blood; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013375:Substance Withdrawal Syndrome / Q000097:blood
chemical_list: D008691:Methadone; D010634:Phenobarbital