Cyclosporin A, a powerful immunosuppressant in vivo and in vitro in the dog, fails to induce tolerance.
D000818:Animals; D003524:Cyclosporins; D003602:Cytotoxicity, Immunologic; D004285:Dogs; D006085:Graft Survival / Q000187:drug effects; D007108:Immune Tolerance / Q000187:drug effects*; D007166:Immunosuppressive Agents; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000187:drug effects; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes; D008934:Mitogens / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000009:adverse effects / Q000627:therapeutic use*; D016038:Skin Transplantation; D013997:Time Factors
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D008934:Mitogens; D010456:Peptides, Cyclic