Positive selection of colicin cured cells by mitomycin C in Klebsiella pneumoniae.
A colicinogenic strain of Klebsiella pneumoniae (MirM7cx) was treated with chemical and physical agents in an attempt to cure it from colicin. Mitomycin C was the only agent able to eliminate the extrachromosomal element from the strain. A simple method to isolate colicin cured cells of K. pneumoniae is described.
D003086:Bacteriocin Plasmids / Q000187:drug effects / Q000528:radiation effects; D007711:Klebsiella pneumoniae / Q000187:drug effects*; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology*; D013696:Temperature
D008937:Mitomycins; D016685:Mitomycin