title: The coexistence of systemic lupus erythematosus and psoriasis.
abstract: Systemic and discoid lupus erythematosus (LE) have both been reported in association with psoriasis. Four additional patients who had systemic LE are reported. All of them had a high titer of antinuclear antibodies (ANAs) and were SS-A(Ro)-negative. Only one patient exhibited photosensitivity. SS-A(Ro) antibodies do not appear to be specific markers for the coexistence of LE and psoriasis, and screening for them in all psoriatics prior to ultraviolet B phototherapy is not recommended. Pitfalls in the management of patients with systemic LE and psoriasis are discussed.
mesh_terms: D000328:Adult; D000906:Antibodies / Q000276:immunology; D000974:Antibodies, Antinuclear / Q000276:immunology; D000941:Antigens / Q000276:immunology; D001324:Autoantigens; D003378:Counterimmunoelectrophoresis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D005779:Immunodiffusion; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008297:Male; D011565:Psoriasis / Q000150:complications* / Q000276:immunology; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D014157:Transcription Factors / Q000276:immunology; D000097585:SS-B Antigen; D000099207:SS-A Antigen
chemical_list: D000906:Antibodies; D000974:Antibodies, Antinuclear; D000941:Antigens; D001324:Autoantigens; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D014157:Transcription Factors; D000097585:SS-B Antigen; D000099207:SS-A Antigen; C116006:RO60 protein, human