title: [Rhesus-prophylaxis during interventions in early pregnancy].
abstract: Surgical interventions in early pregnancy are an important contribution to the Rh IgG utilization gap in Rh-negative women. Ectopic pregnancy, spontaneous and induced abortion and amniocentesis call for IgG prophylaxis. In abortions no immunization was found before the sixth week of pregnancy, thereafter the standard dose of 200 to 300 micrograms Anti-D should be applied, a reduced dose of 50 micrograms is recommended in early abortions before 12 weeks. In ectopic pregnancy prophylaxis is omitted in a high percentage. A further reduction of Rh-immunization in pregnant women can only be achieved by prophylaxis on large scale in early pregnancy.
mesh_terms: D000028:Abortion, Induced; D000022:Abortion, Spontaneous / Q000276:immunology; D000328:Adult; D000649:Amniocentesis; D004306:Dose-Response Relationship, Immunologic; D004899:Erythroblastosis, Fetal / Q000517:prevention & control*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000276:immunology; D007074:Immunoglobulin G / Q000008:administration & dosage; D007231:Infant, Newborn; D007518:Isoantibodies / Q000008:administration & dosage*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011271:Pregnancy, Ectopic / Q000276:immunology; D012204:Rh-Hr Blood-Group System; D014594:Uterine Neoplasms / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System
vernacular_title: Rhesus-Prophylaxe bei Eingriffen in der Frühschwangerschaft.