The effect of alpha, alpha'-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene on human blood platelet structural physiology.
alpha, alpha'-Bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene enhances human blood platelet membrane integrity by exerting a stabilizing action at the level of the dense tubular system in surface membrane complexes known to sequester platelet calcium.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000328:Adult; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D002118:Calcium / Q000097:blood; D002462:Cell Membrane / Q000648:ultrastructure; D003094:Collagen / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D008854:Microscopy, Electron; D009557:Nipecotic Acids / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects
D001095:Arachidonic Acids; D009557:Nipecotic Acids; C043099:alpha, alpha'-bis(3-(N,N-diethylcarbamoyl)piperidino)-4-xylene; D016718:Arachidonic Acid; D000244:Adenosine Diphosphate; D003094:Collagen; D002118:Calcium; D004837:Epinephrine