[Monoamine oxidase and diamine oxidase activity of the tissues of rats in the convulsive phase of oxygen poisoning].
Monoamine oxidase type A activity with substrate serotonine and type B with substrate p-nitrophenylethylamine decreases is rats' brain, liver, heart and blood during oxygen convulsions. Substrate specificity of the enzyme type A alters in all tissues studied. Diamine oxidase activity decreases in brain, lungs and liver approximately in 2 times and increases in blood at 48%. Histamine content increases in all tissues in 3-4 times, in blood--in 12 times. The role of observed changes in the mechanism of oxygen intoxication is discussed.
D006631:Amine Oxidase (Copper-Containing) / Q000378:metabolism*; D000818:Animals; D003641:Deamination; D005260:Female; D006632:Histamine / Q000378:metabolism; D006931:Hyperbaric Oxygenation / Q000009:adverse effects; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D010100:Oxygen / Q000506:poisoning*; D010627:Phenethylamines / Q000378:metabolism; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000201:enzymology*; D012701:Serotonin / Q000378:metabolism; D013379:Substrate Specificity / Q000187:drug effects; D014018:Tissue Distribution
D010627:Phenethylamines; C044350:4-nitrophenethylamine; D012701:Serotonin; D006632:Histamine; D006631:Amine Oxidase (Copper-Containing); D008995:Monoamine Oxidase; D010100:Oxygen
Aktivnost' monoaminoksidazy i diaminoksidazy v tkaniakh krys v sudorozhnuiu fazu kislorodnoĭ intoksikatsii.