Treatment of acute maxillary sinusitis. Erythromycin base and phenoxymethyl-penicillin (penicillin V).
One hundred patients with acute maxillary sinusitis have been studied. The diagnosis was made clinically and confirmed radiologically, using a roentgenological 6-point score for mucous membrane thickening and secretion. Fifty patients in each group were treated with either erythromycin base or phenoxymethyl-penicillin (penicillin V). The roentgenological state of each sinus was classified on the 1st, 5th, 10th, and 15th day, giving an objective evaluation of the treatment effect. There was no significant difference between the two treatment modes as to therapeutic outcome, and the results are compared with those of a larger material of 1220 patients with acute maxillary sinusitis studied in the same way at Lundby Hospital since 1970 (25 different treatment modes).
D000208:Acute Disease; D000328:Adult; D004341:Drug Evaluation; D004917:Erythromycin / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology; D009092:Mucous Membrane / Q000473:pathology; D010404:Penicillin V / Q000009:adverse effects / Q000627:therapeutic use*; D011897:Random Allocation; D012852:Sinusitis / Q000188:drug therapy* / Q000473:pathology
D004917:Erythromycin; D010404:Penicillin V