title: An immunological study of delta-aminolevulinic acid dehydratase specificity consistent with the phylogeny of species.
abstract: Rabbit antibody directed to homogeneously purified mouse liver delta-aminolevulinic acid dehydratase cross-reacted with the enzyme in erythrocytes, spleen, kidney and brain in the mouse. The antibody also cross-reacted with the enzyme in the rat, hamster and gerbil, but not in the rabbit, guinea pig, cattle, chick embryo, and human. In contrast, rabbit antibody against the human enzyme partially recognized the monkey enzyme, but not the enzyme in the other species. The species specificity of delta-aminolevulinic acid dehydratase in this study was consistent with the phylogenetic evolution of the species examined.
mesh_terms: D000818:Animals; D002417:Cattle; D002642:Chick Embryo; D006224:Cricetinae; D003429:Cross Reactions; D005849:Gerbillinae; D006168:Guinea Pigs; D006801:Humans; D005779:Immunodiffusion; D008253:Macaca mulatta; D051379:Mice; D000623:Porphobilinogen Synthase / Q000276:immunology*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D014018:Tissue Distribution
chemical_list: D000623:Porphobilinogen Synthase