title: Blood coagulation and coagulation tests.
abstract: The hemostatic mechanism has evolved to provide efficient protection from traumatic blood loss and yet maintain the blood in a fluid state in the circulation as a whole. Recent advances in biochemistry have provided both detailed understanding of hemostasis and clinically useful coagulation assays to exploit this understanding. Clinicians now have the means to delineate most of the hemostatic problems of clinical significance.
mesh_terms: D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000502:physiology; D001780:Blood Coagulation Tests / Q000379:methods*; D005169:Factor VIII / Q000502:physiology; D005170:Factor X / Q000502:physiology; D015951:Factor Xa; D005337:Fibrin / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen / Q000378:metabolism; D005342:Fibrinolysis; D006467:Hemophilia A / Q000503:physiopathology; D006801:Humans; D011517:Prothrombin Time; D013917:Thrombin / Q000378:metabolism; D013918:Thrombin Time; D014813:Vitamin K Deficiency / Q000503:physiopathology; D014842:von Willebrand Diseases / Q000503:physiopathology
chemical_list: D001779:Blood Coagulation Factors; D005338:Fibrin Fibrinogen Degradation Products; D005169:Factor VIII; D005170:Factor X; D005337:Fibrin; D005340:Fibrinogen; D013917:Thrombin; D015951:Factor Xa