Comparison of fluorescence polarization immunoassay and bioassay of vancomycin.
Human serum samples were analyzed for vancomycin concentrations by two different methods: the fluorescence polarization immunoassay and the disk plate bioassay. Each assay method offered acceptable precision. The correlation between both assay methods was excellent (correlation coefficient = 0.985). Excluding technical time, the bioassay was the least expensive method to perform but was more labor intensive than the fluorescence polarization immunoassay.
D001412:Bacillus subtilis / Q000187:drug effects; D001681:Biological Assay; D005454:Fluorescence Polarization; D006801:Humans; D007118:Immunoassay; D013171:Spores, Bacterial / Q000187:drug effects; D014640:Vancomycin / Q000097:blood* / Q000494:pharmacology
D014640:Vancomycin