Iron and gadolinium chelates as contrast agents in NMR imaging: preliminary studies.
Iron (Fe2+) and gadolinium (Gd3+) chelated to ethylenediaminetetraacetic acid and Gd3+ chelated to diethylenetriamine pentaacetic acid have been used as contrast agents in nuclear magnetic resonance imaging of the normal kidney and cerebral infarction in rabbits. All three agents produced observable changes with inversion-recovery images and marked changes in T1.
D000818:Animals; D002544:Cerebral Infarction / Q000175:diagnosis; D003287:Contrast Media; D004492:Edetic Acid; D005290:Ferric Compounds; D005682:Gadolinium; D066298:In Vitro Techniques; D007501:Iron; D007668:Kidney / Q000033:anatomy & histology; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011817:Rabbits; D001743:Urinary Bladder / Q000033:anatomy & histology
D003287:Contrast Media; D005290:Ferric Compounds; D009942:Organometallic Compounds; C041365:gadolinium EDTA; D004369:Pentetic Acid; D004492:Edetic Acid; D005682:Gadolinium; D007501:Iron; C019179:Fe(III)-EDTA