End-tidal CO2 monitoring. Its use in the diagnosis and management of malignant hyperthermia.
Two cases of malignant hyperthermia are described where the earliest sign was a rise in the end-tidal CO2 concentration. This led to nearly immediate detection and adequate treatment with sodium dantrolene. These cases demonstrate the efficacy of monitoring end-expired CO2 concentrations in patients at risk from malignant hyperthermia, as well as a means for following the adequacy of treatment.
D002245:Carbon Dioxide / Q000502:physiology*; D002648:Child; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000188:drug therapy; D008991:Monitoring, Physiologic; D013990:Tidal Volume; D013997:Time Factors
D002245:Carbon Dioxide; D003620:Dantrolene