Association of ankylosing spondylitis and monoclonal gammopathy: clinical case report and pathogenetic considerations.
Monoclonal gammopathy has rarely been reported in ankylosing spondylitis. We observed a patient with ankylosing spondylitis and monoclonal gammopathy with no signs of malignancy, chronic infections or amyloidosis. This association may show some possible pathogenetic mechanisms involved in these two different diseases of still uncertain etiology.
D006680:HLA Antigens / Q000235:genetics; D015796:HLA-B27 Antigen; D006801:Humans; D006942:Hypergammaglobulinemia / Q000235:genetics / Q000276:immunology*; D007070:Immunoglobulin A / Q000378:metabolism*; D007145:Immunoglobulin kappa-Chains; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000235:genetics / Q000276:immunology*
D006680:HLA Antigens; D015796:HLA-B27 Antigen; D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains