Central venous concentrations of immunoreactive prostaglandins E, F, and 6-keto-prostaglandin F1 in eclampsia.
Concentrations of prostaglandins E, F, and 6-keto-prostaglandin F1 alpha were estimated in central venous blood and amniotic fluid in 21 women with eclampsia and 16 healthy pregnant controls. Central venous blood concentrations of 6-keto-prostaglandin F1 alpha and prostaglandin E were significantly lower in patients than controls before delivery and remained reduced for at least 48 hours after delivery. Low concentrations of prostaglandins E and 6-keto-prostaglandin F1 alpha are probably directly related to the pathogenesis of eclampsia.
D015121:6-Ketoprostaglandin F1 alpha / Q000032:analysis / Q000097:blood*; D000293:Adolescent; D000328:Adult; D000653:Amniotic Fluid / Q000032:analysis; D004461:Eclampsia / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D011247:Pregnancy; D011458:Prostaglandins E / Q000032:analysis / Q000097:blood*; D011460:Prostaglandins F / Q000032:analysis / Q000097:blood*
D011458:Prostaglandins E; D011460:Prostaglandins F; D015121:6-Ketoprostaglandin F1 alpha