Neuroendocrine predictors of the antidepressant effect of partial sleep deprivation.
Twenty-one patients with major depressive disorder were studied to establish the relationship between selective neuroendocrine responses and the antidepressant response to partial sleep deprivation. Dexamethasone suppression and normal thyrotropin response to TRH were associated with a positive mood response.
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000097:blood / Q000628:therapy; D003866:Depressive Disorder / Q000097:blood / Q000628:therapy*; D003907:Dexamethasone; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012892:Sleep Deprivation; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D013973:Thyrotropin-Releasing Hormone; D003907:Dexamethasone; D013972:Thyrotropin; D006854:Hydrocortisone