Immunoglobulin G1 Fc in colostral whey.
Two IgG1 fragments were isolated from bovine colostral whey. Based on gel diffusion analysis, both fragments originated from the Fc portion of the molecule but were not identical to IgG1 Fc prepared by papain cleavage. The molecular weights were determined to be 66,000 and 14,000 daltons and it was hypothesized that the larger fragment could be a polymer of the smaller. No IgG1 Fab or IgG2 fragments could be demonstrated.
D000818:Animals; D002007:Brucellosis, Bovine / Q000276:immunology*; D002417:Cattle; D002850:Chromatography, Gel; D003126:Colostrum / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005779:Immunodiffusion / Q000662:veterinary; D007122:Immunoelectrophoresis; D007141:Immunoglobulin Fc Fragments / Q000032:analysis*; D007128:Immunoglobulin Fragments / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007785:Lactose / Q000276:immunology*; D008970:Molecular Weight; D011247:Pregnancy
D007141:Immunoglobulin Fc Fragments; D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G; D007785:Lactose