A new aminoglycoside antibiotic G-367 S1, 2'-N-formylsisomicin fermentation, isolation and characterization.
A new aminoglycoside antibiotic, G-367 S1 (2'-N-formylsisomicin, C20H37N5O8) produced by a rare actinomycetes, Dactylosporangium thailandense G-367 (FERM-P 4840) has been isolated by column chromatography on a cation-exchange resin. G-367 S1 is active against Gram-positive and Gram-negative bacteria.
D000191:Actinomycetaceae / Q000032:analysis; D000617:Aminoglycosides / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D001412:Bacillus subtilis / Q000187:drug effects; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D012853:Sisomicin / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D013055:Spectrophotometry, Infrared
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C042502:2'-N-formylsisomycin; D012853:Sisomicin