[Eicosanoids released in vitro by human alveolar macrophages from normal subjects and asthmatics].
Unstimulated alveolar macrophages incubated with arachidonic acid [1-14C] release both lipoxygenase and cyclooxygenase metabolites. The nature of these eicosanoids is dependent on the incubation time with the labeled arachidonic acid and on the pathological lung profile.
D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001249:Asthma / Q000378:metabolism*; D004537:Eicosanoic Acids / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008084:Lipoxygenase / Q000378:metabolism; D008168:Lung / Q000166:cytology; D008264:Macrophages / Q000378:metabolism*; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism; D013997:Time Factors
D001095:Arachidonic Acids; D004537:Eicosanoic Acids; D016718:Arachidonic Acid; D008084:Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases
Eicosanoïdes libérés in vitro par les macrophages alvéolaires humains de sujets normaux et de sujets asthmatiques.