title: Yeast killer toxin and an immunity protein are processed from a composite precursor.
abstract: Yeast killer toxin is a secreted protein that kills sensitive cells by forming an ion-conducting channel. The toxin is synthesized as a larger composite precursor containing two toxin subunits and an immunity protein. The processing and action of this precursor and its components provide an attractive system for studying these cellular events common to eukaryotes.
mesh_terms: D000595:Amino Acid Sequence; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D005800:Genes, Fungal; D055646:Killer Factors, Yeast; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009154:Mutation; D009183:Mycotoxins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D011498:Protein Precursors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011499:Protein Processing, Post-Translational / Q000235:genetics; D015003:Yeasts / Q000235:genetics / Q000378:metabolism
chemical_list: D005656:Fungal Proteins; D055646:Killer Factors, Yeast; D009183:Mycotoxins; D011498:Protein Precursors