title: Change in fixed-charge in the thick filament lattice of Limulus striated muscle with sarcomere shortening.
abstract: A highly significant increase in fixed-charge occurs in the A-bands of Limulus striated muscle following activation and sarcomere shortening. This is in striking contrast to vertebrate striated muscle. Treatment with either papain or alkaline phosphatase reduces this fixed-charge. The increase in charge may serve as a motive force in thick filament shortening.
mesh_terms: D000085:Acetates / Q000494:pharmacology; D019342:Acetic Acid; D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D003599:Cytoskeleton / Q000502:physiology*; D004533:Egtazic Acid / Q000494:pharmacology; D006737:Horseshoe Crabs; D066298:In Vitro Techniques; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology; D009210:Myofibrils / Q000502:physiology*; D012518:Sarcomeres / Q000502:physiology*; D013045:Species Specificity
chemical_list: D000085:Acetates; D004533:Egtazic Acid; D019342:Acetic Acid