Development of the lizard limb as shown by the distribution of [35S]sulphate incorporation.
In the forelimb of the lizard, Chalcides ocellatus (Forskal), the chondrogenic pattern is laid down in a proximodistal direction commencing with the proximal regions. The chondrogenic skeletal pattern along the antero-posterior axis gives humerus, radius, ulna and the distal region. The radius and ulna differ in their length and level of sulphation. The end result is a periodic pattern resembling that in other amniotes. The peripheral areas and distal region show an almost uniform uptake of [35S]sulphate, the basement membrane taking up [35S]sulphate at a higher rate between embryonic stages with limb lengths 0.2 mm and 0.75 mm.
D000818:Animals; D001345:Autoradiography; D002809:Chondroitin Sulfates / Q000096:biosynthesis; D005552:Forelimb / Q000196:embryology*; D008116:Lizards / Q000196:embryology*; D011884:Radius / Q000196:embryology; D013462:Sulfur Radioisotopes; D014457:Ulna / Q000196:embryology
D013462:Sulfur Radioisotopes; D002809:Chondroitin Sulfates