Radiotherapy in sarcoidosis of the larynx: case report and review of the literature.
Sarcoidosis infrequently involves the larynx, but resultant airway obstruction will often prompt the need for therapeutic intervention. Systemic and intralesional corticosteroids as well as various surgical approaches have been advocated. We report a case of a 36-year-old man with biopsy proven laryngeal sarcoidosis. The patient became refractory to corticosteroids and was treated with megavoltage radiotherapy as an alternative to tracheostomy. A gradual and complete clinical recovery was observed. The radiation techniques are presented, and the literature regarding laryngeal sarcoidosis is reviewed. Megavoltage radiotherapy is a viable treatment option in this disorder.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000402:Airway Obstruction / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D007818:Laryngeal Diseases / Q000503:physiopathology / Q000532:radiotherapy*; D008297:Male; D011882:Radiotherapy, High-Energy; D012507:Sarcoidosis / Q000503:physiopathology / Q000532:radiotherapy*
D000305:Adrenal Cortex Hormones