'Clear line' formation by immunodiffusion of tetanus toxoid and mixtures of distinct monoclonal antibodies.
Single monoclonal antibodies could not form any precipitin line with tetanus toxoid in Ouchterlony analysis. However, some mixtures of two distinct monoclonal antibodies formed a visible precipitin line (conventional line), while others formed a transparent, just barely visible line, which we call a 'clear line'.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D005779:Immunodiffusion; D051379:Mice; D008807:Mice, Inbred BALB C; D013745:Tetanus Toxoid / Q000276:immunology*
D000911:Antibodies, Monoclonal; D013745:Tetanus Toxoid