title: Cutaneous calculus - its pathogenesis.
abstract: The cutaneous calculus of 11 patients were examined. Histologically they were classified into three types: the first type, seen in an early lesion, consisted of a basophilic mass; the second type consisted of a mass and various-sized granules; and the third type consisted entirely of granules. Histochemically, the mass contained acid mucopolysaccharides. In the granules neutral mucopolysaccharides were found. There were numerous, vacuolated mast cells and various-sized, calcified amorphous areas evident with electron microscopic examination of an early lesion.
mesh_terms: D002137:Calculi / Q000378:metabolism / Q000473:pathology*; D006025:Glycosaminoglycans / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D012867:Skin / Q000378:metabolism / Q000473:pathology*; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology*
chemical_list: D006025:Glycosaminoglycans