Hairy-cell leukemia complicating coeliac disease: report of a case and discussion of possible pathogenetic mechanisms.
10-28% of the patients with chronic coeliac disease develop a second malignancy, such as non-Hodgkin's lymphomas, particularly of the histiocytic type, and adenocarcinomas. The second tumor may arise in the intestinal tract or in other organs. We describe here a patient who developed a tartrate-resistant, acid phosphatase-positive, hairy-cell leukemia after a history of chronic coeliac disease. In the literature, no similar case has been described as yet.
D002446:Celiac Disease / Q000097:blood / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000097:blood / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D013158:Splenic Diseases / Q000097:blood