title: [Genetik risk from diagnostic x-ray procedures? A critical evaluation of epidemiologic studies (author's transl)].
abstract: This essay introduces epidemiologic studies concerned with the question whether diagnostic x-ray procedures might be the cause of an increased genetic risk. All studies have selected Down's syndrome (mongolism) as genetic indicator. They indiscriminately present the opinion of the respective author. Approximately one half of the studies conclude that radiation exposure will not influence the spontaneous incidence of Down's syndrome in diagnostics, the other half finds a positive relationship between frequent radiation exposure and the incidence of the syndrome. For various reasons, explained in detail, the results of the studies under discussion are suitable for forming hypotheses, but should not be viewed as providing evidence.
mesh_terms: D000328:Adult; D004314:Down Syndrome / Q000453:epidemiology / Q000209:etiology*; D004812:Epidemiologic Methods; D005260:Female; D005860:Germany, West; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007564:Japan; D008297:Male; D008396:Maryland; D008423:Maternal Age; D009154:Mutation; D010063:Ovum / Q000528:radiation effects*; D011247:Pregnancy; D011829:Radiation Dosage; D011859:Radiography / Q000009:adverse effects*; D012306:Risk; D012606:Scotland; D013997:Time Factors
vernacular_title: Genetisches Risiko durch röntgendiagnostische Massnahmen? Kritische Betrachtung epidemiologischer Studien.