Lymphocyte-mediated cytotoxicity and humoral antibodies in human pregnancy.
Lymphocyte-mediated cytotoxicity, antibody-dependent cell cytotoxicity and complement-dependent antibody assays were used to study maternal immune response to fetal antigens present on cord lymphocytes at delivery. Among 24 cell-mediated lympholysis tests, 4 were found slightly positive and accompanied by a complement-dependent antibody and/or an antibody-dependent cell cytotoxicity response. The humoral immune response was found more often positive than the cellular response.
D000906:Antibodies; D000920:Antibody-Dependent Cell Cytotoxicity; D003602:Cytotoxicity, Immunologic; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006680:HLA Antigens; D006801:Humans; D007111:Immunity, Cellular; D007231:Infant, Newborn; D007961:Leukocyte Migration-Inhibitory Factors; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology*; D010920:Placenta / Q000276:immunology; D011247:Pregnancy
D000906:Antibodies; D006680:HLA Antigens; D007961:Leukocyte Migration-Inhibitory Factors