A comparison of the diminution rates of lead in blood and lead mobilized by CaEDTA after termination of occupational exposure: a long-term observation in two lead workers.
CaEDTA 20 mg/kg was administered weekly for 3.5 years after termination of occupational exposure to two lead workers. The diminution half-lives for lead in blood and urine lead mobilized by CaEDTA were 4.8 and 3.3 years respectively for subject 1 following 28 years exposure and 3.3 and 2.0 years respectively for subject 2 following 26 years exposure. The difference in the diminution rate between lead in blood and lead mobilized by CaEDTA was significant in subject 2 (p less than 0.05).
D004492:Edetic Acid / Q000627:therapeutic use*; D006207:Half-Life; D006801:Humans; D007855:Lead Poisoning / Q000097:blood / Q000188:drug therapy* / Q000652:urine; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood / Q000188:drug therapy* / Q000652:urine; D013054:Spectrophotometry, Atomic; D013997:Time Factors
D004492:Edetic Acid