Maternal plasma inhibition of prostaglandin synthase during human pregnancy, parturition and the puerperium.
To study the possibility that circulating endogenous inhibitor(s) of prostaglandin synthesis (EIPS) represent a control mechanism for prostaglandin production during human pregnancy and parturition, we have measured maternal plasma EIPS levels serially during pregnancy, labour and the puerperium, and cross-sectionally during the course of labour. No significant trends were detected in relation to pregnancy or parturition. These results do not support a role for maternal plasma EIPS in the control of prostaglandin production during human pregnancy or labour.
D016861:Cyclooxygenase Inhibitors; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D009930:Organic Chemicals; D049590:Postpartum Period; D011247:Pregnancy; D011451:Prostaglandin-Endoperoxide Synthases / Q000097:blood; D013997:Time Factors
D016861:Cyclooxygenase Inhibitors; D009930:Organic Chemicals; C030137:prostaglandin synthase inhibitor, endogenous; D011451:Prostaglandin-Endoperoxide Synthases