title: [Effect of 3-hydroxymethyl-N-methylpiperidine (4-chlorophenoxyacetate) hydrochloride on feeding behavior. Toxicity and neuropsychopharmacology].
abstract: The 3-hydroxymethyl N-methyl piperidine (4-chlorophenoxy) acetate, hydrochloride, A, has been tested for its effect on feeding behavior. This first non-amphetamine substance, with low toxicity and without psychotropic activity, affects the satiety center by reducing gold thioglucose-induced obesity in mice.
mesh_terms: D000818:Animals; D001067:Appetite Depressants; D006051:Aurothioglucose / Q000037:antagonists & inhibitors; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D006016:Glycolates / Q000494:pharmacology* / Q000633:toxicity; D006801:Humans; D008297:Male; D051379:Mice; D009765:Obesity / Q000139:chemically induced / Q000188:drug therapy / Q000523:psychology; D010880:Piperidines / Q000494:pharmacology* / Q000633:toxicity; D011596:Psychomotor Disorders / Q000139:chemically induced; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001067:Appetite Depressants; D006016:Glycolates; D010880:Piperidines; D006051:Aurothioglucose; C043993:3-hydroxymethyl-N-methylpiperidyl (4-chlorophenoxy)acetate
vernacular_title: Effet du chlorhydrate (chloro-4 phénoxyacétate) de N-méthyl hydroxyméthyl-3 pipéridine sur le comportement alimentaire. Toxicité et neuropsychopharmacologie.