[Acute inflammation and hyperalgesia: their consequences on the responses of various neurons of the ventrobasal thalamic complex in rats].
Neuronal responses elicited in the ventrobasal thalamic complex by somatic noxious stimuli are facilitated early in the course of carrageenin-induced acute inflammation, (i) the responses evoked by noxious stimuli applied on the injected paw were enhanced (50-300%); (ii) similar increase was also observed for responses obtained from preexisting receptive fields distinct from the injection site; (iii) moreover, new responses could be elicited by noxious stimuli applied in initially unresponsive areas. These data suggest the involvement of central mechanisms underlying these changes.
D000818:Animals; D002351:Carrageenan; D004195:Disease Models, Animal; D006930:Hyperalgesia / Q000503:physiopathology*; D006941:Hyperesthesia / Q000503:physiopathology*; D007249:Inflammation / Q000503:physiopathology*; D009474:Neurons / Q000502:physiology*; D009619:Nociceptors / Q000503:physiopathology*; D051381:Rats; D013788:Thalamus / Q000503:physiopathology*
D002351:Carrageenan
Inflammation aiguë et hyperalgie: leurs conséquences sur les réponses de certains neurones du complexe ventrobasal du thalamus chez le rat.