title: Various factors which affect the rate of development of tolerance and physical dependence to abused drugs.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004361:Drug Tolerance; D006801:Humans; D008691:Methadone / Q000494:pharmacology; D008692:Methadyl Acetate / Q000494:pharmacology; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D013045:Species Specificity; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D009270:Naloxone; D009020:Morphine; D008692:Methadyl Acetate; D008691:Methadone