[Comparative activity of erythrocyte 17 beta-hydroxysteroid dehydrogenase in man and the rat: effect of plasma].
Human erythrocytes, which contain an active 17 beta-hydroxysteroid-dehydrogenase, transform dehydroepiandrosterone, delta 4-androstenedione and estrone, more rapidly in buffered medium than when kept into plasma. The rat has a peculiar behaviour: the conversion of substrates is very high above the man's one, whether in buffered medium or in blood: the plasma influence is negligible. Plasma permutation reveals that the rat's one, which does not slow down the erythrocyte activity of the rat, slakens the man's one; the human plasma which slows up the human erythrocyte, has only a light action on the rat's one.
D015067:17-Hydroxysteroid Dehydrogenases; D000328:Adult; D000818:Animals; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D010949:Plasma; D051381:Rats; D013045:Species Specificity; D013379:Substrate Specificity
D015067:17-Hydroxysteroid Dehydrogenases
Activité comparée de la 17 beta-hydroxystéroïde-déshydrogénase érythrocytaire chez l'homme et le rat: influence du plasma.