Inhibition by quercetin of the promoting effect of teleocidin on skin papilloma formation in mice initiated with 7,12-dimethylbenz[a]anthracene.
Quercetin markedly suppressed the promoting effect of teleocidin on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene. This activity of quercetin may have some bearing on the fact that quercetin is not carcinogenic despite showing mutagenicity.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000470:Alkaloids / Q000037:antagonists & inhibitors*; D000818:Animals; D001551:Benz(a)Anthracenes; D001835:Body Weight / Q000187:drug effects; D002273:Carcinogens; D004347:Drug Interactions; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D008235:Lyngbya Toxins; D051379:Mice; D010212:Papilloma / Q000139:chemically induced*; D011794:Quercetin / Q000494:pharmacology*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D012878:Skin Neoplasms / Q000139:chemically induced*; D013997:Time Factors
D000470:Alkaloids; D001551:Benz(a)Anthracenes; D002273:Carcinogens; D005419:Flavonoids; D008235:Lyngbya Toxins; C022176:teleocidins; D015127:9,10-Dimethyl-1,2-benzanthracene; D011794:Quercetin