[Demonstration of anti-pancreatic cellular immunity in insulin-dependent diabetics].
A significant inhibition of insulin response was found after incubation of islet cells with blood lymphocytes from 18 out 20 insulin-dependent diabetics. No inhibition was found in 22 control subjects.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D003602:Cytotoxicity, Immunologic; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007328:Insulin / Q000378:metabolism / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000378:metabolism; D008297:Male; D051379:Mice; D008875:Middle Aged; D010179:Pancreas / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D001323:Autoantibodies; D007328:Insulin
Mise en évidence d'une immunité cellulaire anti-pancréatique chez des diabétiques insulino-dépendants.