Salivary gland tumors induced by 32P.
The oncogenic power of 32P was demonstrated in salivary glands. An intraglandular injection of 0.25 mCi of chromic colloidal phosphate (32P) was administered to young adult Wistar rats. Seven months post-injection, tumors began to appear in the neck region in 64% of the rats. The tumors were sarcomas (50%), carcinomas (35.70%), and carcino-sarcomas (14.28%).
D000818:Animals; D002277:Carcinoma / Q000209:etiology / Q000473:pathology; D008297:Male; D009374:Neoplasms, Experimental / Q000209:etiology / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010761:Phosphorus Radioisotopes / Q000009:adverse effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012468:Salivary Gland Neoplasms / Q000209:etiology* / Q000473:pathology; D012509:Sarcoma / Q000209:etiology / Q000473:pathology
D010761:Phosphorus Radioisotopes