Genetically engineered vaccines: problems and promises.
Determinants of important protective antigens from a variety of viral, bacterial and parasite pathogens have been successfully cloned and expressed in novel hosts using recombinant DNA techniques. The use of these cloned determinants in the development of new vaccines, including immunologically defined subunit vaccines, genetically defined live attenuated vaccines, and synthetic peptide vaccines is described.
D000818:Animals; D001424:Bacterial Infections / Q000517:prevention & control; D001428:Bacterial Vaccines; D005818:Genetic Engineering; D006801:Humans; D010272:Parasitic Diseases / Q000517:prevention & control; D014614:Vaccines, Synthetic; D014765:Viral Vaccines; D014777:Virus Diseases / Q000517:prevention & control
D001428:Bacterial Vaccines; D014614:Vaccines, Synthetic; D014765:Viral Vaccines