title: Trypanosoma cruzi: strain selection by different schedules of mouse passage of an initially mixed infection.
abstract: From an initial double infection in mice, established by simultaneous and equivalent inocula of bloodstream forms of strains Y and F of Trypanosoma cruzi, two lines were derived by subinoculations: one (W) passaged every week, the other (M) every month. Through biological and biochemical methods only the Y strain was identified at the end of the 10th and 16th passages of line W and only the F strain at the 2nd and 4th passages of line M. The results illustrate strain selection through laboratory manipulation of initially mixed populations of T. cruzi.
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000469:parasitology*; D005260:Female; D051379:Mice; D014349:Trypanosoma cruzi / Q000302:isolation & purification* / Q000472:pathogenicity