title: [EEG activation using bemegride in the diagnosis of epilepsy. 2. Catamnestic studies].
abstract: 43 patients were evaluated catamnestically 5-10 years after a bemegride test in order to proof its relevance. The bemegride test was considered as diagnostically helpful in 37 cases (86%) based on observations of the course. It had been false negative in four cases (9,3%), and false positive in two cases (4,7%). The occurrence of epileptic attacks is indicated by the activation of regular and irregular spike-wave complexes as well as other specific epileptic discharges. These could be activated by an average threshold of 68,5 mg or 1,09 mg/kg body weight in 86,2% of all patients with epileptic attacks. The threshold dose was lower in cases of primary generalized attacks than in complex focal attacks. The indication for the bemegride test is restricted.
mesh_terms: D000328:Adult; D001534:Bemegride / Q000494:pharmacology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D005189:False Positive Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012640:Seizures / Q000503:physiopathology
chemical_list: D001534:Bemegride
vernacular_title: EEG Aktivierung mit Bemegrid in der Epilepsie-Diagnostik. Teil 2: Katamnestische Untersuchungen.