title: [Obstetrical aspects in successes and failures of rhesus-prophylaxis].
abstract: Before the general introduction of Rhesus-prophylaxis the frequency of morbus haemolyticus neonatorum was about 0.6%. In spite of the simple collection of "Rhesus-negative" mothers and the administration of the Rhesus-prophylaxis there are still some cases of morbus haemolyticus neonatorum; in our department 2 cases (or 0.11%) last year. The possible causes of non-successful Rhesus-prophylaxis are: immunisation during a previous abortion; immunisation during a previous delivery or a non-adequate blood-transfusion; in a previous delivery there was a macrotransfusion and therefore the doses of Rhesus-prophylaxis too small; the administration of Rhesus-prophylaxis was too late (later than 72 hours post partum); inadequate standardisation or storage of the drug; immunisation during the present pregnancy.
mesh_terms: D000328:Adult; D004899:Erythroblastosis, Fetal / Q000517:prevention & control*; D005260:Female; D005312:Fetal Blood / Q000166:cytology; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000008:administration & dosage*; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System; D013997:Time Factors
chemical_list: D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System
vernacular_title: Geburtshilfliche Aspekte bei den Erfolgen und Misserfolgen der Rhesus-Prophylaxe.