[Diagnostic possibilities and therapy in the acute phase of myocardial infarct].
An analysis is given for the differential therapeutical drug treatment in the acute phase of myocardial infarction. In first line the correction of hemodynamic disorders is taken into consideration following an exact diagnosis of hemodynamic dysfunction. On that basis different subgroups can be identified. In 5% of the patients exists a hypoperfusion. The therapy of choice is a substitution of volume. 25% of the patients with an acute myocardial infarction develop acute left ventricular failure, with a mortality of 40 to 50%. The treatment of choice in patients with clinical signs of congestion of the lungs but normal cardiac output will be diuretics and vasodilators. In patients with global insufficiency afterload reduction with vasodilators and/or stimulation with positive inotropic substances such as catecholamines has proven successful. Cardiac glycosides have lost their place in the treatment of acute but not of chronic cardiac failure. The use of intraaortic counterpulsation will be reserved for patients with mechanical complications.
D004071:Digitalis Glycosides / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004280:Dobutamine / Q000627:therapeutic use; D004298:Dopamine / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy*; D005996:Nitroglycerin / Q000627:therapeutic use; D009599:Nitroprusside / Q000627:therapeutic use; D009638:Norepinephrine / Q000627:therapeutic use; D011379:Prognosis; D014665:Vasodilator Agents / Q000627:therapeutic use
D004071:Digitalis Glycosides; D004232:Diuretics; D014665:Vasodilator Agents; D009599:Nitroprusside; D004280:Dobutamine; D005996:Nitroglycerin; D004298:Dopamine; D009638:Norepinephrine
Diagnostische Möglichkeiten und Therapie in der Akutphase des Myokardinfarktes.