[Antitumor effect of new lymphokine OH-1 on BDF1 mice bearing Lewis lung carcinoma].
Antitumor effect of new lymphokine extracted from BALL-1 cells derived from human acute lymphocytic leukemia was investigated using BDF1 mice bearing Lewis lung carcinoma. This antitumor lymphokine is called OH-1. The antitumor effect of OK-1 on transplanted main tumor was great, but less effective than cyclophosphamide. However, the antitumor effect on OH-1 on metastatic tumor was comparably high as with cyclophosphamide, both macroscopically and functionally.
D000818:Animals; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D008175:Lung Neoplasms / Q000473:pathology / Q000628:therapy*; D008222:Lymphokines / Q000627:therapeutic use*; D051379:Mice; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation
D008222:Lymphokines; D008937:Mitomycins; D016685:Mitomycin; D004317:Doxorubicin; D003520:Cyclophosphamide