Significance of positive direct anti-globulin test for cord blood--in administration of anti-d immunoglobulin for postpartum immunoprophylaxis.
The aim of this paper is to reconsider the significance of a positive direct antiglobulin test for cord blood, especially in the case of administration of anti-D immunoglobulin for postpartum immunoprophylaxis. In 421 samples of cord blood, 14(3.3%) positive results were obtained in a direct antiglobulin test. From these cord blood cells, antibodies were eluted and identified as follows: anti-A, 6; anti-B, 6; anti-E+ c, 1 and anti-Jra, 1. Thus, not all cases giving positive results in a direct antiglobulin test in cord blood at delivery have anti-D antibodies. And the elution test should be done in order to specifically identify the coated antibody as anti-D or non-anti-D.
D000017:ABO Blood-Group System / Q000276:immunology; D000328:Adult; D000751:Anemia, Neonatal / Q000276:immunology*; D001787:Blood Group Incompatibility / Q000175:diagnosis*; D003298:Coombs Test; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D006801:Humans; D007072:Immunoglobulin D / Q000276:immunology; D007231:Infant, Newborn; D008297:Male; D006473:Postpartum Hemorrhage / Q000517:prevention & control*; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D000017:ABO Blood-Group System; D007072:Immunoglobulin D; D012204:Rh-Hr Blood-Group System