The fibrinolytic system in pre-eclampsia.
Plasma fibrinolytic activity and plasma inhibitory activity against urokinase and tissue activator were measured in primigravidae with moderate or severe pre-eclampsia and in gestation-matched primigravidae with uncomplicated pregnancy. The mean levels of fibrinolytic activity and inhibitory activity against urokinase and tissue activator did not differ significantly between the pre-eclampsia and uncomplicated pregnancy groups. The pattern of inhibitory fractions of plasminogen-depleted plasma from pre-eclamptic and uncomplicated primigravidae after gel filtration on sephadex G-100 was similar.
D000293:Adolescent; D000328:Adult; D002850:Chromatography, Gel; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D010960:Plasminogen Activators / Q000037:antagonists & inhibitors; D015849:Plasminogen Inactivators; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D014568:Urokinase-Type Plasminogen Activator / Q000037:antagonists & inhibitors
D015849:Plasminogen Inactivators; D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator