title: Usefulness of enzyme-1 and immunohistochemistry in the diagnosis of juvenile xanthogranuloma.
abstract: Skin biopsies from two children with juvenile xanthogranuloma were studied. Enzyme- and immunohistochemistry was used to establish the mononuclear phagocytic nature of the proliferating dermal elements. The usefulness of both techniques in the diagnosis and the differential diagnosis of this disease is suggested.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008297:Male; D009283:Naphthol AS D Esterase / Q000378:metabolism; D012867:Skin / Q000201:enzymology / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology
chemical_list: D009283:Naphthol AS D Esterase; D000135:Acid Phosphatase