[The effect of adjuvant substances on the antigenic activity of cellular antirabies vaccine in experiments on cattle].
Trials were conducted with young cattle to study the effect of adjuvants, applied subcutaneously and intramuscularly, upon the antigenic activity of live and inactivated cell rabies vaccine prepared from the Vnukovo -32 strain at the level of the 107th series cell passage. Cerebral vaccine of Fermi type was also used in the trials for comparison. The antibodies were parallelly titrated by four methods, three of which were conducted in vitro. The levels of antirabies antibodies indicate a possibility of fortifying the antigenic activities of inactivated vaccine by means of the Bioveta Nitra oil adjuvant and the activities of the live vaccine by means of adjuvant prepared after Buchnev . The antigenic activity of the Czechoslovak-produced cerebral rabies vaccine for veterinary use is extraordinarily low.
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002417:Cattle; D004341:Drug Evaluation; D011819:Rabies Vaccines / Q000276:immunology*; D011820:Rabies virus / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D011819:Rabies Vaccines
Vplyv adjuvantných látok na antigénnu aktivitu bunkovej antirabickej vakcíny v pokusoch na hovädzom dobytku.