Molecular cloning of cDNA for murine interleukin-3.
The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide. The predicted amino acid sequence indicates that formation of mature interleukin-3 involves proteolytic removal of not only the signal peptide but additional amino-terminal amino acids.
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D005260:Female; D007377:Interleukin-3; D008222:Lymphokines / Q000235:genetics*; D051379:Mice; D009865:Oocytes; D010957:Plasmids; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics; D014982:Xenopus laevis
D007377:Interleukin-3; D008222:Lymphokines; D012333:RNA, Messenger; D004247:DNA