[In vitro and in vivo studies using 111 indium oxine, 111 indium oxine sulfate and 99m Tc oxine in erythrocyte labeling].
The optimal conditions for red blood cell labelling using 111indium oxine, 111indium oxine sulphate and 99mTc oxine were established both in vitro as well as in vivo. The coagulant had no effect on labelling efficiency. Other variables such as the incubation time, temperature, duration, cell number and concentration of the complex exert a significant influence on labelling efficiency. Labelling efficiency of red blood cells is very high also under non-optimum conditions as compared with other cells (leucocytes, platelets).
D004912:Erythrocytes / Q000000981:diagnostic imaging / Q000187:drug effects; D006801:Humans; D006912:Hydroxyquinolines; D066298:In Vitro Techniques; D007204:Indium / Q000494:pharmacology; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives / Q000097:blood / Q000494:pharmacology; D011877:Radionuclide Imaging; D013667:Technetium; D013696:Temperature; D013997:Time Factors
D006912:Hydroxyquinolines; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D007204:Indium; C032950:indium oxine; D015125:Oxyquinoline; C041314:technetium Tc 99m 8-hydroxyquinoline; D013667:Technetium
In-vitro- und In-vivo-Untersuchungen mit 111Indium-Oxin-111Indium-Oxin-Sulfat und 99mTc-Oxin zur Erythrozytenmarkierung.