title: The effect of dietary lactose on the early recovery from protein-energy malnutrition. II. Indices of nutrient absorption.
abstract: Absorption of dietary energy, nitrogen, carbohydrates and calcium, and retention of nitrogen and calcium were studied in 20 children with protein-energy malnutrition of the edematous type, using metabolic balance techniques and breath H2 analysis, to assess the advisability of using lactose-containing formulas in the rehabilitation of severely malnourished children. Ten patients received for 45 days a diet formula based on cows' milk (intact milk) and 10 similar children received the same formula pretreated with beta-galactosidase to hydrolyze the lactose (hydrolyzed milk). Dietary intakes were gradually increased to reach, on the 8th day, 4 g of protein and 150 kcal/kg. There were no differences between groups with respect to absorption or retention of the index nutrients. Postprandial carbohydrate malabsorption was occasionally observed in two patients with servings of the intact milk formula, and in one with the hydrolyzed milk diet. When the nutritional quality of a diet is assessed, the amount of nutrients that are absorbed and utilized are more important than the small, incompletely absorbed fractions that do not have significant metabolic or clinical implications. Therefore, the use of milk as the protein source for recovery diets is not contraindicated in the routine treatment of PEM.
mesh_terms: D000818:Animals; D002136:Calcium, Dietary / Q000378:metabolism; D002417:Cattle; D002675:Child, Preschool; D004040:Dietary Carbohydrates / Q000008:administration & dosage* / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism; D002149:Energy Intake; D006801:Humans; D007223:Infant; D007225:Infant Food; D007408:Intestinal Absorption; D007732:Kwashiorkor / Q000178:diet therapy*; D007785:Lactose / Q000008:administration & dosage* / Q000378:metabolism; D007787:Lactose Intolerance / Q000517:prevention & control; D008297:Male; D008892:Milk; D009584:Nitrogen / Q000378:metabolism; D011502:Protein-Energy Malnutrition / Q000178:diet therapy*
chemical_list: D002136:Calcium, Dietary; D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D007785:Lactose; D009584:Nitrogen