[Subcorneal pustulosis and monoclonal gammapathies].
Subcorneal pustular dermatosis (Sneddon-Wilkinson) is a rare dermatosis. In some cases, it is associated with a monoclonal gammopathy, most often Ig A. This association is considered as a salient feature of SPD, and is not present in other pustuloses, like pustular psoriasis, which may be related to SPD. The physiopathology of the neutrophilic dermatoses and the role of Ig A are briefly discussed.
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007070:Immunoglobulin A / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D008297:Male; D009504:Neutrophils / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000150:complications* / Q000276:immunology / Q000473:pathology
D007070:Immunoglobulin A; D007146:Immunoglobulin lambda-Chains
Pustuloses sous-cornées et gammapathies monoclonales.