Primary cutaneous lymphoplasmacytoid lymphoma (immunocytoma).
A case of localized lymphoplasmacytoid lymphoma of the skin was studied by light and electron microscopy, by immunological methods, and by enzyme cytochemistry. It illustrated usual and unusual features of a type of B-cell lymphoma in the skin and presented problems in differential diagnosis. Histologically, its cellularity varied from a monomorphous to a pleomorphic pattern that was highly suggestive of a nonspecific inflammatory reaction or a pseudolymphoma, but from the presence of a clone of IgG (lambda)-producing plasmacytoid cells, it was established that it consisted in fact of lymphoplasmacytoid and polymorphic subtypes of an immunocytomatous lymphoma.
D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007146:Immunoglobulin lambda-Chains / Q000276:immunology; D008223:Lymphoma / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D010950:Plasma Cells / Q000648:ultrastructure; D010954:Plasmacytoma / Q000175:diagnosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*
D007074:Immunoglobulin G; D007146:Immunoglobulin lambda-Chains