[Wilson's disease in the German Democratic Republic. III. Diagnosis and therapy].
Taking into consideration the manifold symptomatology of Wilson's disease on the one hand and the necessity of an early--possibly already at the asymptomatic stage before the 6th year of life--diagnostic ascertainment on the other hand, the diagnostic approach performed in the GDR is described. Furthermore, the directives of treatment and the successes of treatment are discussed as well as the various side-effects of the D-penicillamine therapy described, in which case the severe nephrotic syndromes are particularly considered.
D000328:Adult; D002570:Ceruloplasmin / Q000172:deficiency; D002648:Child; D003300:Copper / Q000378:metabolism*; D005260:Female; D006580:Genetic Carrier Screening; D006527:Hepatolenticular Degeneration / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007105:Immune Complex Diseases / Q000139:chemically induced; D007223:Infant; D008297:Male; D009393:Nephritis / Q000139:chemically induced; D010396:Penicillamine / Q000009:adverse effects / Q000627:therapeutic use*
D003300:Copper; D002570:Ceruloplasmin; D010396:Penicillamine
Untersuchungen zur Wilsonschen Erkrankung in der DDR. Teil III. Diagnose und Therapie.