Monoclonal gammopathy in Sézary syndrome. Report of three cases and review of the literature.
Three patients with Sézary syndrome had monoclonal gammopathy: two had gammopathy of unknown significance and one had myeloma. The frequency of the association of Sézary syndrome and monoclonal gammopathy seems to be lower than previously suggested. However, it does emphasize that the presence of T-cell cutaneous disease does not preclude B-cell clonal proliferation.
D000368:Aged; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000473:pathology*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012751:Sezary Syndrome / Q000150:complications* / Q000276:immunology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007146:Immunoglobulin lambda-Chains; D007136:Immunoglobulins