[Effect of phenoxybenzamine on mesenteric blood flow in irradiated rats].
Reactivity of the superior mesenteric artery has been studied in rat Wistar by infusion of biogenic amines (noradrénaline, dopamine, serotonin, acetylcholine and histamine) in presence of phenoxybenzamine. A decrease in reactivity of the post-synaptic alpha receptor located on the mesenteric vascular smooth muscle cell was seen three days after irradiation by 2 Kr.
D000818:Animals; D001679:Biogenic Amines / Q000494:pharmacology; D001808:Blood Vessels / Q000187:drug effects*; D008297:Male; D008638:Mesenteric Arteries / Q000187:drug effects; D010643:Phenoxybenzamine / Q000494:pharmacology*; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D014965:X-Rays
D001679:Biogenic Amines; D010643:Phenoxybenzamine
Effet de la phénoxybenzamine sur le flux sanguin mésentérique du rat irradié.