[Comparison of enteral resorption rates of free amino acids and oligopeptides].
During the last fifteen years it was demonstrated, that in addition to the amino acid transport system of human small intestine which is known since longer time, there is as well a transport system for peptides. Actually transport of complete di- or tripeptides through the brushborder membrane may possibly play a major role in intestinal protein assimilation of man and may have some kinetic advantages in regard to amino acid resorption in healthy persons and patients with gastroenterological diseases. In studies on single peptides, protein hydrolysates and mixtures of crystalline dipeptides it could be shown, that resorption rates of amino acids separated from small peptides are greater and more constant than resorption of the amino acids in free form. The explanation for this may be, that the peptide carrier system apparently has a bigger transport capacity than the amino acid transport system. This is well decreasing competition between substrates to a minimum.
D000596:Amino Acids / Q000378:metabolism*; D004044:Dietary Proteins / Q000378:metabolism; D004151:Dipeptides / Q000378:metabolism; D004750:Enteral Nutrition; D005767:Gastrointestinal Diseases / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D009842:Oligopeptides / Q000378:metabolism*
D000596:Amino Acids; D004044:Dietary Proteins; D004151:Dipeptides; D009842:Oligopeptides
Vergleich der enteralen Resorptionsraten freier Aminosäuren und Oligopeptide.