Importance of symptoms in recognizing nitroprusside toxicity.
Symptoms of nitroprusside toxicity may precede the commonly described physiologic derangements. A characteristic sequence of symptoms associated with thiocyanate toxicity was exhibited by a patient who received a seven-day infusion of nitroprusside. The recognition of symptoms of nitroprusside toxicity is especially crucial when nitroprusside is infused over a prolonged period, in high doses, or in the presence of renal failure.
D000787:Angina Pectoris / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced; D005292:Ferricyanides / Q000506:poisoning*; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009599:Nitroprusside / Q000008:administration & dosage / Q000506:poisoning*; D013997:Time Factors
D005292:Ferricyanides; D009599:Nitroprusside