title: Pathogenicity of natural and experimental listeriosis in newly hatched chicks.
abstract: The pathogenicity of Listeria monocytogenes for newly hatched chickens exposed to natural infection was examined. Organisms entered through the alimentary tract and dissemination followed bacteraemia. Among a number of symptoms recorded were unilateral and bilateral toe paralysis. In addition to gross abnormalities in the following tissues, histological lesions were seen in the liver, spleen, heart and kidneys of all infected chicks but brain lesions were observed only in birds with central nervous system involvement. The organism was recovered from some tissues derived from apparently healthy chicks as well as those with listeriosis. The use of trypsin in the isolation process increased the probability of a positive result from tissues, reduced the storage time needed and had no adverse effect on the rate of organism growth.
mesh_terms: D000367:Age Factors; D000818:Animals; D002645:Chickens; D007422:Intestines / Q000382:microbiology; D008089:Listeria monocytogenes / Q000302:isolation & purification / Q000472:pathogenicity*; D008088:Listeriosis / Q000473:pathology / Q000662:veterinary*; D011201:Poultry Diseases / Q000473:pathology*