[Concept of class in relation to first-generation cephalosporins].
The authors consider differences in answer of the first generation cephalosporins against several strains of Gram-negative and Gram-positive bacteria, and suggest a revision of the "class" concept as regards sensitivity response of the above mentioned cephalosporins.
D001419:Bacteria / Q000187:drug effects*; D002437:Cefazolin / Q000494:pharmacology; D002506:Cephalexin / Q000494:pharmacology; D002511:Cephalosporins / Q000145:classification* / Q000494:pharmacology; D002512:Cephalothin / Q000494:pharmacology; D002515:Cephradine / Q000494:pharmacology; D002954:Citrobacter / Q000187:drug effects; D004754:Enterobacter / Q000187:drug effects; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007709:Klebsiella / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011513:Proteus mirabilis / Q000187:drug effects; D011514:Proteus vulgaris / Q000187:drug effects; D012475:Salmonella / Q000187:drug effects; D012705:Serratia / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects
D002511:Cephalosporins; D002515:Cephradine; D002437:Cefazolin; D002506:Cephalexin; D002512:Cephalothin
Considerazioni sul concetto di "classe" relativamente alle cefalosporine di prima generazione.