Histochemical localization of carbonic anhydrase in the inner ear.
Carbonic anhydrase was histochemically located in chinchilla inner ear tissues. A strong carbonic anhydrase reaction was observed in the spiral ligament cells, Boettcher's cells, the external sulcus cells, and the stria vascularis (intermediate and/or basal cells). The enzymatic reaction was also positive in the supporting cells of all vestibular sensory epithelia, as well as in the dark cells and transitional cells of the utricle and saccule. Some epithelial cells of the endolymphatic sac were also positive. It is speculated that this enzyme may be involved in: 1) ionic or fluid regulation of the endolymph, 2) removal of CO2 from the inner ear tissue near the sensory cells, and 3) otoconia formation and maintenance.
D000818:Animals; D002256:Carbonic Anhydrases / Q000032:analysis*; D002682:Chinchilla; D003051:Cochlea / Q000201:enzymology; D007758:Ear, Inner / Q000033:anatomy & histology / Q000201:enzymology*; D004712:Endolymphatic Sac / Q000201:enzymology; D006651:Histocytochemistry; D014722:Vestibule, Labyrinth / Q000201:enzymology
D002256:Carbonic Anhydrases