Isolation of enterochelin from the peritoneal washings of guinea pigs lethally infected with Escherichia coli.
Escherichia coli secretes enterochelin while infecting normal guinea pigs. Since production of enterochelin is a well-characterized response to an iron-restricted environment, this work establishes that host iron-binding proteins do indeed influence the metabolism of the invading organism.
D000818:Animals; D004758:Enterobactin / Q000302:isolation & purification / Q000378:metabolism*; D004926:Escherichia coli / Q000254:growth & development / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000378:metabolism* / Q000382:microbiology; D006168:Guinea Pigs; D010529:Peritoneal Cavity / Q000382:microbiology*; D012694:Serine / Q000031:analogs & derivatives*
D004758:Enterobactin; D012694:Serine