Clinical pancreas and islet transplantation. Part 1: registry statistics and an overview.
Pancreas transplantation has evolved into a safe and moderately successful procedure for the treatment of selected patients whose diabetic complications are more serious than the potential side effects of chronic immunosuppression. Islet transplantation, however, remains largely unsuccessful. An overview of pancreas and islet transplantation experience worldwide is presented. Results of transplants according to association with kidney transplants, technique, immunosuppression, and organ preservation are evaluated.
D000328:Adult; D000818:Animals; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology / Q000601:surgery*; D006085:Graft Survival; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation; D016035:Pancreas Transplantation; D011292:Premedication; D012042:Registries; D014184:Transplantation, Homologous; D014481:United States
D006680:HLA Antigens; D007166:Immunosuppressive Agents