[Synergistic mechanisms in the combined carcinogenic action of radiation and other factors: the role of mutation and the activation of oncogenes and genes controlling growth factor synthesis].
A hypothesis is proposed on the role in the radiation carcinogenesis of mutation and (or) activation of combination of the several prooncogenes, some of which are homologous on the growth factors or probably to the actin. The antibodies to the products of oncogenes may be used to study mechanisms of carcinogenic action of radiation and others factors or even as diagnostic tool or remedy.
D000818:Animals; D005786:Gene Expression Regulation / Q000528:radiation effects*; D005809:Genes, Regulator / Q000528:radiation effects*; D006133:Growth Substances / Q000096:biosynthesis*; D009154:Mutation; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000235:genetics; D009857:Oncogenes / Q000528:radiation effects*
D006133:Growth Substances
O mekhanizmakh sinergizma pri kombinirovannom kantserogennom deĭstvii izlucheniĭ i drugikh faktorov: rol' mutatsii i aktivatsii onkogenov i genov, kontroliruiushchikh sintez rostovykh faktorov.