Efficacy of topical anaesthetics.
By means of a recently developed electronical optical esthesiometer the efficacy of five different topical anaesthetics was compared. The influence of vehicle and concentration was also investigated. From the results it can be concluded that the drugs currently available are of suitable local anaesthetic effect with little influence of the vehicle or preservative agent used.
D000779:Anesthetics, Local / Q000494:pharmacology* / Q000592:standards; D003315:Cornea / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004582:Electronics, Medical / Q000295:instrumentation; D006801:Humans; D009883:Ophthalmic Solutions; D011343:Procaine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D012677:Sensation / Q000187:drug effects
D000779:Anesthetics, Local; D009883:Ophthalmic Solutions; D011343:Procaine; C005298:benoxinate