[Hypothesis: immune complex glomerulonephritis and auto-immunity (author's transl)].
Experimental studies on the NZBxNZW mouse lupus disease and on the development of immune complex (IC) glomerulonephritis in mouse infected with Escherichia coli lead us to state the following hypothesis: two types of factors are implicated in the development of immune complex glomerulonephritis: 1) specific factors leading to the production of IC involving antigens from the triggering agents; 2) non specific factors leading to the production of IC involving auto-antigens.
D000818:Animals; D000917:Antibody Formation; D001324:Autoantigens / Q000633:toxicity; D001327:Autoimmune Diseases / Q000276:immunology*; D005921:Glomerulonephritis / Q000276:immunology*; D007105:Immune Complex Diseases / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains
D001324:Autoantigens
Glomérulonéphrite à complexes immuns et auto-immunité.