Successful treatment of keratoderma hereditaria mutilans with an aromatic retinoid.
Clinical features and treatment of keratoderma hereditaria mutilans (Vohwinkel's syndrome) are described in an 11-year-old boy. The disease, in particular the mutilating complications (pseudo-ainhum), responded satisfactorily to the oral administration of etretinate, an aromatic retinoid.
D000284:Administration, Oral; D000387:Ainhum / Q000188:drug therapy* / Q000473:pathology; D002648:Child; D003251:Constriction, Pathologic / Q000188:drug therapy / Q000473:pathology; D004487:Edema / Q000188:drug therapy; D005050:Etretinate / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010859:Pigmentation Disorders / Q000188:drug therapy; D013577:Syndrome; D014212:Tretinoin / Q000031:analogs & derivatives*
D014212:Tretinoin; D005050:Etretinate