Hydralazine-induced cholangitis.
This report describes a 59-year-old woman, who, after an initial reaction to hydralazine, inadvertently took the drug again. She promptly developed symptoms of acute cholangitis--fever, right upper quadrant tenderness, obtundation, and hypotension. Cholecystectomy was performed and no obstruction or infection of the biliary tract was present. Perioperative studies support a diagnosis of hydralazine-induced acute cholangitis, a side effect of the drug which has not been previously described.
D000208:Acute Disease; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000473:pathology; D002761:Cholangitis / Q000139:chemically induced* / Q000473:pathology; D002764:Cholecystitis / Q000139:chemically induced / Q000473:pathology; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects*; D008875:Middle Aged
D006830:Hydralazine