Different states of transplantation tolerance, and the problem of inheritance of tolerance.
In agreement with previous results, we failed to observe hereditary transmission of transplantation tolerance in the progeny of tolerant male mice when tested by skin grafting. At the same time we showed that the detection of the tolerance state depended on the test of immunity used. The possibility has not excluded that positive results with hereditary transmission of tolerance via fathers [1-3] may be due to the appropriate detection systems.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D005260:Female; D006084:Graft Rejection; D007108:Immune Tolerance; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL / Q000235:genetics*; D016038:Skin Transplantation; D013154:Spleen / Q000637:transplantation*