A rare example of weakened expression of the Kell (K1) antigen.
Random typing of donor units revealed a donor whose red blood cells gave very weak reactions with all anti-Kell (anti-K1) antisera. All other Kell-system antigen was present in four generations of the donor's family. The red-cell morphology is normal in all family members with the weakened K1 antigen. A consistent hypothesis is that the weak antigen is inherited through a variant allele at the Kell locus and represents a quantitative, not a qualitative, change.
D000483:Alleles; D001789:Blood Group Antigens / Q000235:genetics*; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D007626:Kell Blood-Group System / Q000235:genetics* / Q000276:immunology; D008297:Male; D010375:Pedigree
D001789:Blood Group Antigens; D007626:Kell Blood-Group System