A lectin from elder (Sambucus nigra L.) bark.
A lectin was isolated from elder (Sambucus nigra) bark by affinity chromatography on fetuin-agarose. It is a tetrameric molecule (Mr 140000) composed of two different subunits of Mr 34500 and 37500 respectively, held together by intramolecular disulphide bridges. The lectin is a glycoprotein and is especially rich in asparagine/aspartic acid, glutamine/glutamic acid, valine and leucine. It is also the first lectin isolated from a species belonging to the plant family Caprifoliaceae.
D000596:Amino Acids / Q000032:analysis; D002241:Carbohydrates; D055598:Chemical Phenomena; D002621:Chemistry; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D004591:Electrophoresis, Polyacrylamide Gel; D006384:Hemagglutination / Q000187:drug effects; D037102:Lectins / Q000302:isolation & purification* / Q000494:pharmacology; D014176:Protein Biosynthesis / Q000187:drug effects
D000596:Amino Acids; D002241:Carbohydrates; D037102:Lectins