[Bromocriptine therapy from the 2d month of pregnancy induces regression of neuro-ophthalmologic complications caused by macroprolactimona].
In a 32 year old woman harboring a macroprolactinoma with supra and laterosellar extension, bromocriptine was able to reduce the size of the tumor and the very high circulating levels of prolactin, restoring ovulatory menstrual cycles. At the 8th week of a not recommended pregnancy, the patient presented bitemporal superior quadrantopsia and headache. After reinstitution of bromocriptine therapy the woman showed a rapid improvement of neuroophtalmological complications. The treatment was continued till the delivery; a normal baby was born.
D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009897:Optic Chiasm / Q000187:drug effects; D009901:Optic Nerve Diseases / Q000188:drug therapy / Q000209:etiology*; D010911:Pituitary Neoplasms / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011261:Pregnancy Trimester, First; D011388:Prolactin / Q000378:metabolism*
D001971:Bromocriptine; D011388:Prolactin
Il trattamento con bromocriptina dal secondo mese di gravidanza provoca regressione delle complicanze neuroftalmologiche da macroprolattinoma.