[Combination chemotherapy and radiotherapy. Differential effect, on the intestinal syndrome, of fractionated irradiation with fractionated drug administration].
We studied the different effects of 5 FU fractional doses before and after fractional irradiation on the intestinal syndrome. The results indicate that the more effective administration of 5 FU is one single dose per week 9 hours after the last irradiation in a two weeks schedule.
D000818:Animals; D004195:Disease Models, Animal; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000009:adverse effects; D007410:Intestinal Diseases / Q000139:chemically induced / Q000209:etiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D013577:Syndrome
D005472:Fluorouracil
Association de chimiothérapie et de radiothérapie. Effet différentiel sur le syndrome intestinal de l'association du fractionnement dans le temps de l'irradiation et de la drogue.