[Plasma lipoproteins and their interaction with cells].
Modern ideas on interaction of blood plasma lipoproteins with a cell and lipid transport to and out of the cell are considered. Receptor-mediated uptake of low-density lipoproteins by the parenchymatous and connective-tissue type cells as well as nonregulated endocytic uptake of native and modified lipoproteins by the macrophagal type cells are shown to play a certain part in maintaining cholesterol homeostasis in the organism. Characterization is given for conditions under which there occur accumulation of lipoprotein cholesterol in a cell and formation of a foamy cell a "precursor and companion" of the atherosclerotic affection of arteries.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D001692:Biological Transport; D002478:Cells, Cultured; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D002914:Chylomicrons / Q000378:metabolism; D004727:Endothelium / Q000378:metabolism; D005487:Foam Cells / Q000378:metabolism; D006801:Humans; D008074:Lipoproteins / Q000097:blood / Q000378:metabolism*; D008075:Lipoproteins, HDL / Q000097:blood / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000097:blood / Q000378:metabolism; D008079:Lipoproteins, VLDL / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D009130:Muscle, Smooth / Q000166:cytology / Q000378:metabolism; D011817:Rabbits; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D002914:Chylomicrons; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D002784:Cholesterol
Lipoproteiny plazmy krovi i ikh vzaimodeĭstvie s kletkoĭ.