Digitalis toxicity in infants and children.
There is a narrow difference between the therapeutic and toxic ranges of cardiac glycosides. The availability in the past decade of radioimmunoassays for accurate measurement of these glycosides has resulted in an improved understanding of their pharmacokinetics and clinical use. Despite these advances, however, digitalis toxicity is still a common problem in infants and children.
D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000906:Antibodies / Q000032:analysis; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy; D001921:Brain / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004071:Digitalis Glycosides / Q000506:poisoning*; D004077:Digoxin / Q000097:blood / Q000276:immunology / Q000506:poisoning; D004305:Dose-Response Relationship, Drug; D006329:Heart Conduction System / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000032:analysis; D007223:Infant
D000889:Anti-Arrhythmia Agents; D000906:Antibodies; D004071:Digitalis Glycosides; D007140:Immunoglobulin Fab Fragments; D004077:Digoxin