The use of Tc-99m MDP bone scanning in the study of vascularized bone implants: concise communication.
The extent to which the nutrient artery alone is capable of maintaining bone growth in the immature animal was studied by excision and reimplantation of the upper tibia in two groups of puppies. In one group the reimplant was totally devascularized, and in a second group attempts were made to preserve the nutrient vessels to the reimplant. Technetium-99m methylene diphosphonate (Tc-99m MDP) was used to assess the effectiveness with which the nutrient circulation was maintained. With one exception the Tc-99m MDP scans proved to be reliable in indicating the potential for continued growth after reimplantation. It was found that the nutrient artery alone is capable of maintaining longitudinal bone growth in metaphyseal reimplants in immature animals. Complete devascularization results in cessation of growth. The Tc-99m MDP bone scan should prove of critical importance in the assessment of free vascularized transplants of immature bone.
D000818:Animals; D001846:Bone Development; D016025:Bone Transplantation; D001842:Bone and Bones / Q000098:blood supply*; D004164:Diphosphonates; D004285:Dogs; D011875:Radionuclide Angiography; D012092:Replantation; D013667:Technetium; D013669:Technetium Tc 99m Medronate; D013977:Tibia / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery
D004164:Diphosphonates; D013667:Technetium; D013669:Technetium Tc 99m Medronate