[Detection of suppressor lymphocytes in the blood of oncological patients by using a 3-component lymphocyte mixed culture].
A 3 component mixed lymphocyte culture was used to identify the suppressor cell activity of lymphocytes in the blood of patients suffering from osteogenic sarcoma, osteoblastoclastoma and lung tumor. The lymphocytes of these patients suppressed the blastogenic reaction of lymphocytes from two unrelated donors. The suppressive activity of the lymphocytes form the patients with bone sarcoma was the strongest. In most cases, a direct correlation was found between the suppressive activities of lymphocytes and serum from the same patients.
D000230:Adenocarcinoma / Q000276:immunology; D001859:Bone Neoplasms / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology; D005870:Giant Cell Tumors / Q000276:immunology*; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects; D007959:Lymphocyte Culture Test, Mixed / Q000379:methods*; D010017:Osteoma, Osteoid / Q000276:immunology*; D012516:Osteosarcoma / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D010835:Phytohemagglutinins
Vyiavlenie limfotsitov-supressorov v krovi onkologicheskikh bol'nykh s pomoshch'iu trekhkomopnentnoĭ smeshannoĭ kul'tury limfotsitov.