Relief of osteoporotic backache with fluoride, calcium, and calciferol.
In a prospective randomized clinical trial comprising 22 postmenopausal women with backache and a halisteretic spine with crush fracture(s), 12 women completed a 12-week therapy with sodium fluoride, calcium and calciferol and 10 with placebo. A statistically significant improvement (p less than 0.05), evaluated by a four-stage scale on pains, infirmity, and consumption of analgesics, was observed in the actively treated patients.
D000368:Aged; D001416:Back Pain / Q000188:drug therapy* / Q000209:etiology; D002118:Calcium / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D004872:Ergocalciferols / Q000627:therapeutic use*; D005260:Female; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications*; D011446:Prospective Studies; D011897:Random Allocation; D012969:Sodium Fluoride / Q000627:therapeutic use*
D004872:Ergocalciferols; D012969:Sodium Fluoride; D005459:Fluorides; D002118:Calcium