Experimental pulpal Arthus allergy.
Rabbits sensitized systemically to ovalbumin displayed skin reactions of the Arthur type and high titers of circulating antibodies. Their incisor pulp was removed at intervals after local challenge with 0.001 ml of 1 percent ovalbumin. Acute inflammatory lesions were demonstrated in the pulp by optical and electron microscopy. Immunofluorescence revealed massive accumulations of antigen-antibody complexes in the lesions, confirming the presence of an Arthur type of allergy.
D000818:Animals; D001183:Arthus Reaction / Q000276:immunology / Q000473:pathology*; D003782:Dental Pulp / Q000276:immunology* / Q000473:pathology / Q000648:ultrastructure; D005455:Fluorescent Antibody Technique; D008854:Microscopy, Electron; D010047:Ovalbumin / Q000276:immunology; D011817:Rabbits
D010047:Ovalbumin