Plasma glucose and pancreatic insulin content in the early phase of streptozotocin-induced diabetes (preliminary results).
The susceptibility of female and male C57Bl/KsJ-mice to multiple low-dose streptozotocin applications was investigated. Both sexes of the strains studied developed hyperglycemia. In the early phase of streptozotocin-applications we failed to observe a strong parallelism between increase of plasma glucose and decrease of pancreatic insulin content.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005260:Female; D007328:Insulin / Q000378:metabolism*; D007515:Islets of Langerhans / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013311:Streptozocin
D001786:Blood Glucose; D007328:Insulin; D013311:Streptozocin