Failure of antibody to carbohydrate-rich gonadotropin to inhibit rapid ovarian growth in landlocked Atlantic salmon.
The discovery of a carbohydrate-poor gonadotropin has resulted in a reassessment of the role of the classical, carbohydrate-rich gonadotropin (Con A II GtH) in teleost ovarian development. Prolonged treatment of landlocked Atlantic salmon with antibody to Con A II GtH failed to inhibit rapid ovarian growth or accumulation of triglyceride or vitellogenin derivative. Sera from antibody-treated fish showed substantial capacity to bind Con A II GtH indicating that antibody treatment successfully removed endogenous Con A II GtH from the circulation. These results are consistent with previous reports that a factor other than Con A II GtH is responsible for stimulating yolk accumulation.
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D002241:Carbohydrates / Q000276:immunology; D005260:Female; D006062:Gonadotropins / Q000276:immunology*; D007457:Iodine Radioisotopes; D010053:Ovary / Q000254:growth & development* / Q000378:metabolism; D012474:Salmon / Q000502:physiology*; D014280:Triglycerides / Q000097:blood / Q000378:metabolism; D014819:Vitellogenins / Q000097:blood / Q000378:metabolism
D000906:Antibodies; D002241:Carbohydrates; D006062:Gonadotropins; D007457:Iodine Radioisotopes; D014280:Triglycerides; D014819:Vitellogenins; C016844:salmon gonadotropin