The effect of cervical dilatation by laminaria on the plasma levels of 15-keto-13,14-dihydro-PGF2 alpha.
Laminaria tents were inserted to induce cervical dilatation prior to suction abortion in 42 primigravidae. The plasma level of 15-keto-13,14-dihydro-PGF2 alpha, the principal metabolite of prostaglandin F 2 alpha, increased during the dilatation period. The gentle dilatation by laminaria tents probably induces an endogenous synthesis of prostaglandins causing a softening of the cervix.
D000293:Adolescent; D000328:Adult; D004107:Dilatation and Curettage / Q000379:methods*; D015237:Dinoprost / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007795:Laminaria; D010946:Plants, Medicinal; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011460:Prostaglandins F / Q000097:blood*; D012624:Seaweed; D014619:Vacuum Curettage
D011460:Prostaglandins F; C008228:15-keto-13,14-dihydroprostaglandin F2alpha; D015237:Dinoprost