Candidemia and sternal Candida albicans osteomyelitis in a patient with chronic lymphatic leukemia.
Sternal osteomyelitis caused by Candida albicans without previous surgery or trauma occurred in a patient with chronic lymphatic leukemia and recurrent skin cancer. The osteomyelitic process healed without antifungal treatment. Three weeks later, following a radical neck dissection, candidemia, without recurrence of the osteomyelitis, was diagnosed and treated successfully with intravenous amphotericin B and 5-fluorocytosin. The presentation of Candida osteomyelitis as a manifestation of disseminated candidiasis in immunocompromised hosts is discussed and the relevant literature is briefly reviewed.
D001853:Bone Marrow / Q000473:pathology; D002177:Candidiasis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications; D010019:Osteomyelitis / Q000209:etiology* / Q000473:pathology; D018805:Sepsis / Q000382:microbiology*; D012878:Skin Neoplasms / Q000150:complications; D013249:Sternum / Q000473:pathology