[Production of hyperimmune sera and immune ascitic fluids to influenza virus protein M by immunization with a protein-polyelectrolyte conjugate].
A conjugate of influenza A virus M protein with an immunostimulating polyelectrolyte was demonstrated to stimulate markedly antibody production in mice. Production in this method of immunization of immune ascitic fluids makes it possible to use this method for generation of highly active immune diagnostic preparations.
D000179:Acrylates / Q000276:immunology*; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001202:Ascitic Fluid / Q000276:immunology*; D007106:Immune Sera / Q000302:isolation & purification*; D007114:Immunization / Q000379:methods; D007074:Immunoglobulin G / Q000032:analysis; D009980:Influenza A virus / Q000276:immunology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011205:Povidone / Q000276:immunology*; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000276:immunology*
D000179:Acrylates; D000914:Antibodies, Viral; D007106:Immune Sera; D007074:Immunoglobulin G; D014763:Viral Matrix Proteins; D014764:Viral Proteins; D011205:Povidone; C036658:acrylic acid
Poluchenie giperimmunnykh syvorotok i immunnykh astsiticheskikh zhidkosteĭ k belku M virusa grippa pri immunizatsii kon''iugatom belka s poliélektrolitom.