Isolation and characterization of the precursor of type M collagen.
A 225000-Mr peptide has been purified from rat chondrosarcoma which is immunologically and biochemically related to type M collagen. Rotary shadowing shows this molecule to be twice the length of the type M molecule and has a prominent kink close to one end. We believe this molecule represents parent type M, the form of the molecule in vivo.
D000818:Animals; D000906:Antibodies / Q000276:immunology; D002813:Chondrosarcoma / Q000032:analysis; D002852:Chromatography, Ion Exchange; D004591:Electrophoresis, Polyacrylamide Gel; D008854:Microscopy, Electron; D011347:Procollagen / Q000276:immunology / Q000302:isolation & purification; D011487:Protein Conformation; D051381:Rats; D011919:Rats, Inbred Strains
D000906:Antibodies; D011347:Procollagen