Activity of epimerases in in vitro cultured fibroblasts.
The process of collagen and proteoglycan synthesis in the in vitro cultured fibroblasts was studied by four original histoenzymological methods: UDP-glucuronic-5-epimerase, hydroxyproline epimerase, UDP-4-epimerase and UDP-N-acetyl-glucosamine epimerase. The process of epimerasization varied in terms of the cell growth stages. Synthesis of collagen and proteoglycans developed in the cells of the same culture but with various intensities in different cell groups.
D000818:Animals; D002478:Cells, Cultured / Q000201:enzymology; D002642:Chick Embryo; D003094:Collagen / Q000096:biosynthesis; D003238:Connective Tissue / Q000201:enzymology*; D005347:Fibroblasts / Q000201:enzymology* / Q000378:metabolism / Q000648:ultrastructure; D007535:Isomerases / Q000032:analysis* / Q000378:metabolism*; D011509:Proteoglycans / Q000096:biosynthesis; D019998:Racemases and Epimerases / Q000032:analysis* / Q000378:metabolism*
D011509:Proteoglycans; D003094:Collagen; D007535:Isomerases; D019998:Racemases and Epimerases