Variability of euchromatic and heterochromatic segment of the Y chromosome in men with malignant tumors and in a control group.
In this study, Y chromosome variability was analyzed in 58 male patients with malignant tumors and 55 healthy male controls. No difference in the size of Y chromosome was established between the two groups studied, but a statistically significant difference in the length of euchromatic and heterochromatic segments was found. A significantly greater length of heterochromatic segments was established in the patients compared with the control group (p less than 0.02). The length of the euchromatic segment was shorter in the patients than in the controls (p less than 0.02).
D006801:Humans; D008297:Male; D009369:Neoplasms / Q000235:genetics*; D011110:Polymorphism, Genetic; D014998:Y Chromosome