Blood group H antigen with globo-series structure. Isolation and characterization from human blood group O erythrocytes.
Blood group H antigen with globo-series structure, reacting with the monoclonal antibody MBrl, was isolated and characterized from human blood group O erythrocytes. The structure was identified by methylation analysis, direct probe mass spectrometry, and 1H-nuclear magnetic resonance spectroscopy as shown below: Fuc alpha 1----2Gal beta 1----3GalNAc beta 1----3Gal alpha 1----4Glc beta 1----1Cer.
D000017:ABO Blood-Group System / Q000276:immunology*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004910:Erythrocyte Membrane / Q000276:immunology; D008401:Gas Chromatography-Mass Spectrometry; D005915:Globosides / Q000032:analysis; D006017:Glycolipids / Q000032:analysis; D006801:Humans; D013058:Mass Spectrometry
D000017:ABO Blood-Group System; D005915:Globosides; D006017:Glycolipids