Mezlocillin enteral absorption in rabbits.
To determine the role of enterohepatic recirculation on its nonlinear elimination, we studied the enteral absorption of mezlocillin in rabbits. Mezlocillin was not substantially absorbed from the stomach or duodenum. We conclude that enterohepatic recirculation does not cause the dose-dependent elimination kinetics of mezlocillin.
D000818:Animals; D005260:Female; D007408:Intestinal Absorption; D007700:Kinetics; D008297:Male; D008802:Mezlocillin; D010406:Penicillins / Q000378:metabolism*; D011817:Rabbits
D010406:Penicillins; D008802:Mezlocillin