Inhibitory effect of amidino-substituted heterocyclic compounds on the amidase activity of plasmin and of high and low molecular weight urokinase and on urokinase-induced plasminogen activation.
D000578:Amidines / Q000494:pharmacology*; D000581:Amidohydrolases / Q000378:metabolism*; D001550:Benzamidines / Q000494:pharmacology; D010450:Endopeptidases / Q000378:metabolism*; D005341:Fibrinolysin / Q000378:metabolism; D006571:Heterocyclic Compounds / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007211:Indoles / Q000494:pharmacology; D008970:Molecular Weight; D010960:Plasminogen Activators / Q000378:metabolism; D014568:Urokinase-Type Plasminogen Activator / Q000378:metabolism* / Q000494:pharmacology
D000578:Amidines; D001550:Benzamidines; D006571:Heterocyclic Compounds; D007211:Indoles; C033570:5-amidinoindole; D010450:Endopeptidases; D010960:Plasminogen Activators; D005341:Fibrinolysin; D014568:Urokinase-Type Plasminogen Activator; D000581:Amidohydrolases