Platelet monoamine oxidase activity in Down's syndrome.
The activity of platelet monoamine oxidase in Down's syndrome cases was significantly lower than that of controls. This difference was found for both males and females, and with tyramine, tryptamine and beta-phenethylamine as substrate. The Km values of the monoamine oxidase towards tryptamine as substrate from controls and Down's syndrome patients were similar.
D000293:Adolescent; D000328:Adult; D001792:Blood Platelets / Q000201:enzymology*; D004314:Down Syndrome / Q000097:blood / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*
D008995:Monoamine Oxidase