Hereditary pyropoikilocytosis: report of two cases from Saudi Arabia.
Hereditary pyropoikilocytosis is a rare type of congenital hemolytic anemia reported only in American black children. We report the first two occurrences in Saudi children. This is an autosomal-recessive trait as proved by normal parents and two affected children. A pathogenetic and probably causal relationship with apparent elliptocytosis seems clear as three sibs have that condition.
D000745:Anemia, Hemolytic, Congenital / Q000097:blood / Q000235:genetics*; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004612:Elliptocytosis, Hereditary / Q000235:genetics; D004912:Erythrocytes / Q000648:ultrastructure; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D012529:Saudi Arabia