Formation of collagen-like fibrils from alpha-elastin.
Collagen-like structures were formed in solutions of alpha-elastin after heating to 57 degrees C and after treatment with absolute ethanol. A complex between acetyl-alpha-elastin and cetyltrimethylammonium bromide showed a similar structure. Thick fibrils (diameter approximately 100 nm), resembling those described by Volpin, et al.12 revealed transversal banding with periodicity of 39 to 62 nm. A possible mechanism for the formation of these fibers is suggested based on hydrophobic interactions.
D000818:Animals; D002417:Cattle; D003094:Collagen / Q000378:metabolism*; D004549:Elastin / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology; D006358:Hot Temperature; D007700:Kinetics; D008022:Ligaments; D046911:Macromolecular Substances; D008854:Microscopy, Electron
D046911:Macromolecular Substances; D000431:Ethanol; D003094:Collagen; D004549:Elastin