Treatment of pharyngeal gonorrhea due to beta-lactamase-producing gonococci.
Between March 1978 and October 1980 seven patients with beta-lactamase-producing gonococci in the pharynx were treated wit spectinomycin of cefuroxime or both. One-day treatment with spectinomycin was effective in only one of six patients and with cefuroxime in only one of four patients. Prolonged treatment with cefuroxime was successful in all five cases so treated.
D002444:Cefuroxime / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000201:enzymology; D010405:Penicillinase / Q000096:biosynthesis; D010608:Pharyngeal Diseases / Q000188:drug therapy* / Q000382:microbiology; D010917:Pivampicillin / Q000627:therapeutic use; D000198:Spectinomycin / Q000627:therapeutic use*
D002511:Cephalosporins; D010917:Pivampicillin; D000198:Spectinomycin; D010405:Penicillinase; D002444:Cefuroxime