[Results of application of cefoperazone to pediatric infections (author's transl)].
Cefoperazone (CPZ) was studied clinically and the following results were obtained. The drug was administered to 21 cases of bacterial infections; respiratory tract infection (17), lymphadenitis (1), urinary tract infection (1), enterocolitis (1) and purulent meningitis (1). The daily dose was 50 approximately 125 mg/kg. The drug was given by one-shot intravenous injection, 3 approximately 4 times a day and the duration of administration was from 3 approximately 18 days. The overall efficacy rate was 81.0%, i.e., excellent in 11 cases, good in 6 cases, moderate in 2 cases and poor in 2 cases. CPZ was potent in the treatment of ampicillin-resistant Haemophilus influenzae meningitis. One patient developed exanthema. No other serious side effects were observed.
D000293:Adolescent; D000367:Age Factors; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002438:Cefoperazone; D002511:Cephalosporins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male
D002511:Cephalosporins; D002438:Cefoperazone