Response to inhaled beta-agonist in a patient receiving beta-adrenergic blockers.
A 52-year-old man receiving long-term hemodialysis and a beta-adrenergic blocker for hypertension had symptoms of acute bronchospasm when exposed to a new hemodialyzer. Resistant to two doses of subcutaneous epinephrine (1 mL of 1:1000 dilution) and one intravenous dose of aminophylline (250 mg), the bronchospasm was rapidly relieved by metaproterenol sulfate given by inhalation one hour later.
D000707:Anaphylaxis / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology; D001986:Bronchial Spasm / Q000139:chemically induced* / Q000188:drug therapy / Q000209:etiology; D002482:Cellulose / Q000009:adverse effects / Q000031:analogs & derivatives; D006801:Humans; D008297:Male; D009921:Metaproterenol / Q000008:administration & dosage; D008875:Middle Aged; D011433:Propranolol / Q000009:adverse effects*; D006435:Renal Dialysis / Q000009:adverse effects
D009921:Metaproterenol; D002482:Cellulose; C009865:cuprammonium cellulose; D011433:Propranolol