[Phenomenon of delayed disruption of telomeric links between chromosomes in polykaryocytes formed from human-Chinese hamster hybrid cells].
The clones MOM-8-1 and MOM-8-3 of human--Chinese hamster cell hybrids were used for induction of the phenomenon of delayed disruption of the telomeric links between chromosomes. Colcemide (0.08 microgram/ml) and 5-bromodeoxyuridine (20 micrograms/ml) were present in cell culture for 30 hours. The dicentrics were observed in tetraploid, hypotetraploid and hypodiploid metaphases. No differences between the clones were found. The hybrid cells were the second object in which the phenomenon under discussion was reproduced.
D000818:Animals; D001973:Bromodeoxyuridine / Q000494:pharmacology; D002875:Chromosomes / Q000187:drug effects / Q000648:ultrastructure*; D006224:Cricetinae; D003412:Cricetulus; D003703:Demecolcine / Q000494:pharmacology; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure*; D013997:Time Factors
D001973:Bromodeoxyuridine; D003703:Demecolcine
Fenomen zaderzhki raspada telomernykh sviazeĭ khromosom v polikariotsitakh, obrazovannykh iz gibridnykh kletok chelovek-kitaĭskiĭ khomiachok.