Evidence that ribosomal protein S10 participates in control of transcription termination.
We report the isolation of an Escherichia coli K-12 strain with a mutation, nusE71, that results in a change in ribosomal protein S10. Phage lambda fails to grow in hosts carrying the nusE71 mutation because the lambda N gene product is not active. The N product regulates phage gene expression by altering transcription complexes so that they can overcome termination barriers. This suggests that a ribosomal protein is involved in antitermination of transcription.
D010582:Bacteriophage lambda / Q000235:genetics*; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004926:Escherichia coli / Q000235:genetics*; D009154:Mutation; D012269:Ribosomal Proteins / Q000032:analysis / Q000235:genetics*; D012270:Ribosomes / Q000378:metabolism; D014158:Transcription, Genetic
D012269:Ribosomal Proteins; C029537:ribosomal protein S10