Ultrastructural and morphometric study of corticosteroid glaucoma in rabbits.
The ultrastructural study of the corneo-scleral trabeculum in steroid induced glaucoma shows a greater endothelial activity and an increase of the ground substance and of the cytoplasmic organelles, as well as a great sensitivity of the ground substance to hyaluronidase. The morphometric study of the cytoplasmic organelles showed a significant difference between treated and non-treated eyes.
D000305:Adrenal Cortex Hormones; D000818:Animals; D003315:Cornea / Q000473:pathology* / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D003907:Dexamethasone; D004727:Endothelium / Q000473:pathology; D005901:Glaucoma / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D006820:Hyaluronic Acid / Q000096:biosynthesis; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D011817:Rabbits; D014129:Trabecular Meshwork / Q000187:drug effects / Q000648:ultrastructure
D000305:Adrenal Cortex Hormones; D003907:Dexamethasone; D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase