Stimulation of glycolysis and accumulation of a stimulator of phosphofructokinase in hepatocytes incubated with vasopressin.
Vasopressin stimulates glycolysis in hepatocytes prepared from fed rats, or from starved rats when incubated with glucose. It causes the stimulation of phosphofructokinase activity and the accumulation of a stimulator of phosphofructokinase, which is probably fructose 2,6-bisphosphate, the recently discovered stimulatory of phosphofructokinase.
D000818:Animals; D004790:Enzyme Induction / Q000187:drug effects; D005934:Glucagon / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D006019:Glycolysis / Q000187:drug effects*; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D010732:Phosphofructokinase-1 / Q000378:metabolism*; D051381:Rats; D013268:Stimulation, Chemical; D014667:Vasopressins / Q000494:pharmacology*
D014667:Vasopressins; D005934:Glucagon; D010732:Phosphofructokinase-1; D005947:Glucose