Ureter replacement by collagen and seromuscular parts of the large bowel in dogs.
The use of stemmed patches and tubes from the seromuscular layer of the colon wall to replace part of the ureter has proven unreliable because of complications such as urinary leakage and invagination, fibrosis, bone formation, shrinkage and disappearance of the intestinal wall due to ischemia and necrosis, causing hydronephrosis and pyelonephritis. The use of tubes and patches of tanned and untanned collagen, implanted in order to study the ingrowth of urothelium and possibly muscle cells, resulted in fibrosis, bone formation, rejection of the material and, in the case of the tubes, complete obstruction with hydronephrosis and destruction of the kidney.
D000818:Animals; D001705:Bioprosthesis / Q000009:adverse effects; D003094:Collagen / Q000627:therapeutic use*; D003106:Colon / Q000601:surgery*; D004285:Dogs; D006084:Graft Rejection; D013524:Surgical Flaps; D014513:Ureter / Q000473:pathology / Q000601:surgery*
D003094:Collagen