[Effect of pineal indoles and testosterone on sex behavior].
The possible action of melatonin and 5-methoxytryptophol, two pineal indoles, upon castrated male rat sexual behaviour with three testosterone dose levels was studied. Both indoles reduced the number of mounts and intromissions. 5-Methoxytryptophol, in addition, decreased the number of ejaculations. The sexual actions of the pineal indoles are prevented by the administration of high testosterone dose levels (500 micrograms/day).
D000818:Animals; D002369:Castration; D004305:Dose-Response Relationship, Drug; D004542:Ejaculation / Q000187:drug effects; D007211:Indoles / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D008297:Male; D008550:Melatonin / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D010870:Pineal Gland / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013739:Testosterone / Q000494:pharmacology*
D007211:Indoles; D013739:Testosterone; C002465:methoxytryptophol; D008550:Melatonin
Actividad de los indoles pineales y la testosterona sobre la conducta sexual.