Multimodal contractile activity of the canine sphincter of Oddi.
Using a high-fidelity recording system, simultaneous manometric measurements of the sphincter of Oddi and duodenum were performed in 6 dogs. The sphincter of Oddi was a high-pressure zone with superimposed phasic activity. The tracings were analyzed according to the distribution of the peak-to-peak contraction intervals (PPI), and a multimodal distribution was consistently found with a basal mode of 3.5 s. If not occurring at this interval, the PPI would be a multiple of this value. These findings suggest that slow-wave control activity is present in the canine sphincter of Oddi. The origin of this control is still unknown.
D014670:Ampulla of Vater / Q000502:physiology*; D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000502:physiology; D008365:Manometry; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000502:physiology*; D011312:Pressure; D009803:Sphincter of Oddi / Q000502:physiology*