Prolonged bleeding time associated with moxalactam administration.
A case of moxalactam-induced coagulopathy is reported. The authors think that this coagulopathy is caused by an effect on platelet aggregation and not by inhibition of vitamin K-dependent clotting factors. It is recommended that bleeding times be routinely checked preoperatively in patients being treated with moxalactam.
D001760:Bleeding Time; D001922:Brain Abscess / Q000188:drug therapy* / Q000601:surgery; D002648:Child; D004359:Drug Therapy, Combination; D006474:Hemorrhagic Disorders / Q000139:chemically induced*; D006801:Humans; D007431:Intraoperative Complications / Q000188:drug therapy; D008297:Male; D008581:Meningitis / Q000188:drug therapy*; D009070:Moxalactam / Q000009:adverse effects* / Q000627:therapeutic use; D010314:Partial Thromboplastin Time; D010974:Platelet Aggregation / Q000187:drug effects; D010979:Platelet Function Tests; D011517:Prothrombin Time; D014812:Vitamin K / Q000627:therapeutic use
D014812:Vitamin K; D009070:Moxalactam