Efficacy of fenbendazole against the swine kidney worm Stephanurus dentatus.
Fenbendazole in ground feed was fed on 3 successive days at the rate of 3 mg/kg of body weight to 15 sows naturally infected with kidney worm (Stephanurus dentatus). Fifteen similar sows were used as nontreated controls. A total of 49 kidney worms were recovered from daily urine samples collected from 10 of the 15 treated sows within 5 days after the 3rd dose of treatment. One control sow passed 10 kidney worms on the 2nd and 3rd days. Urine samples from treated sows became negative for kidney worm eggs by the 5th to 12th posttreatment days, except for urine samples from 1 sow that contained a few eggs on the 12th day and another sow that contained a few eggs on the 19th and 33rd posttreatment days. Urine samples from control sows contained approximately the same number of kidney worm eggs in the posttreatment period as earlier. Compared with that in control sows, the hatchability of the parasite eggs from treated sows was greatly reduced. Kidney worms were not recovered at necropsy from the treated sows and a total of 860 kidney worms were recovered from the control sows (57 av).
D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D005260:Female; D005273:Fenbendazole / Q000627:therapeutic use*; D008099:Liver / Q000469:parasitology; D009349:Nematode Infections / Q000662:veterinary*; D017206:Strongylida Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy* / Q000469:parasitology; D014556:Urine / Q000469:parasitology
D001562:Benzimidazoles; D005273:Fenbendazole