[Protein spectra and phospholipid composition of cholinoreceptor-enriched membranes from rat skeletal muscles after sensitization].
The effect of neisserial sensitization on the protein spectra and phospholipid composition of acetyscholine receptor-rich membrane fragments was investigated in rat skeletal muscles. The sensitization led to substantial changes in the protein spectrum of the cell membranes of the skeletal muscles with high receptor activity in respect to choline. The phospholipid composition of the membranes was found to experience profound transformations. A considerable increase was noted in the content of sphingomye lin and phosphatidylcholine together with a marked drop in the content of phosphatidylethanolamine, phosphatidylinosite and phosphatidylserine.
D000485:Allergens; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D006967:Hypersensitivity / Q000209:etiology / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D009343:Neisseria / Q000276:immunology; D010743:Phospholipids / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D011950:Receptors, Cholinergic / Q000502:physiology*
D000485:Allergens; D010743:Phospholipids; D011506:Proteins; D011950:Receptors, Cholinergic
Belkovye spektry i fosfolipidnyĭ sostav membran, obogashchennykh kholinoretseptorami, iz skeletnykh myshts krys v usloviiakh sensibilizatsii.