Photo-onycholysis from minocycline. Side effects of minocycline therapy.
Minocycline, prescribed for a patient with acne, produced a photosensitivity reaction (photo-onycholysis) involving the fingernails. The onset of this reaction coincided with an increase in sun exposure and cleared several months later, when the drug was discontinued. This type of reaction has been reported to occur in patients taking tetracycline or a member of the tetracycline group of antibiotics, of which minocycline is a member. This appears to be first report of photo-onycholysis due to minocycline.
D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D005260:Female; D006801:Humans; D008911:Minocycline / Q000009:adverse effects* / Q000627:therapeutic use; D009260:Nail Diseases / Q000139:chemically induced*; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013472:Sunlight; D013754:Tetracyclines / Q000009:adverse effects*; D014466:Ultraviolet Rays / Q000009:adverse effects
D013754:Tetracyclines; D008911:Minocycline