Influence of lead acetate on hypersensitivity. Experimental study.
Recent studies showed that lead acetate has an important immunotoxicity for the phagocytic activity as well as humoral and cell-mediated immunity. We studied the influence of lead acetate on immediate and delayed hypersensitivity. The lead acetate exerts an important action on hypersensitivity reactions whether on rat mast cells degranulation (immediate hypersensitivity) or on contact hypersensitivity.
D000818:Animals; D003877:Dermatitis, Contact / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007111:Immunity, Cellular / Q000187:drug effects; D007854:Lead / Q000633:toxicity*; D008407:Mast Cells / Q000187:drug effects; D051379:Mice; D009942:Organometallic Compounds; D010323:Passive Cutaneous Anaphylaxis / Q000187:drug effects; D010853:Picryl Chloride / Q000633:toxicity; D051381:Rats
D009942:Organometallic Compounds; D007854:Lead; C008261:lead acetate; D010853:Picryl Chloride