HLA-DR antigens render resting T cells sensitive to interleukin-2 and induce production of the growth factor in the autologous mixed lymphocyte reaction.
D000042:Absorption; D000911:Antibodies, Monoclonal; D001667:Binding, Competitive; D000949:Histocompatibility Antigens Class II / Q000494:pharmacology*; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D007165:Immunosuppression Therapy; D007376:Interleukin-2 / Q000096:biosynthesis* / Q000494:pharmacology*; D007959:Lymphocyte Culture Test, Mixed; D008222:Lymphokines / Q000096:biosynthesis* / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000949:Histocompatibility Antigens Class II; D007106:Immune Sera; D007376:Interleukin-2; D008222:Lymphokines