The prognostic value of intraoperative pressure gradients with congenital aortic stenosis.
Patients with congenital aortic stenosis are subject to sudden death without prior symptoms. Indications for operation are based on pressure gradients, but intraoperative evaluation of results after relief of obstruction can be subjective and arbitrary. Between September, 1981, and October, 1983, 21 patients underwent operation for relief of congenital aortic stenosis. Fifteen had valvular, 4 had supravalvular, and 2 had subvalvular stenosis. Seven patients were 1 year of age or younger, 2 being 3 days old. Preoperative inotropic support and emergency operation were necessary in 2 patients. Intraoperative pressure gradients were measured in all but the 2 patients who were 3 days old. All patients survived without complications. Intraoperative and postoperative pressure gradients were available in 16 patients. The average preoperative pressure gradient was 76 mm Hg. It was significantly lowered to 20 mm Hg (p less than 0.001) intraoperatively, which compared with 15 mm Hg postoperatively. Three patients had an unsatisfactorily high intraoperative pressure gradient after initial intervention. Immediate reexploration and incision of the rudimentary commissure in 2 and excision of redundant valvular tissue in the other resulted in a more satisfactory pressure gradient without substantial aortic insufficiency. We suggest that measurement of intraoperative pressure gradients can accurately assess the results of therapy and allow the surgeon the option of reexploration for further intervention. Moreover, the high correlation between intraoperative and postoperative pressure gradients can help in planning postoperative management and future cardiac catheterizations.
D000293:Adolescent; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D006352:Heart Ventricles / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007432:Intraoperative Period; D011312:Pressure; D011379:Prognosis