Experimental and clinical studies of mesenteric infarction.
Results of our experimental studies have demonstrated that, during the evolution of mesenteric infarction, lysosomal membrane instability occurs with the release of beta-N acetylhexosaminidase into the portal and systemic circulation. Preliminary clinical results suggest an elevation of the Hex B fraction in mesenteric infarction. Measurements of total and various fractions of beta-N acetylhexosaminidase in the blood may prove to be an early indication of necrosis of the intestine.
D000328:Adult; D000368:Aged; D000818:Animals; D004285:Dogs; D005260:Female; D054819:Hexosaminidase B; D006596:Hexosaminidases / Q000097:blood; D006801:Humans; D007238:Infarction / Q000201:enzymology* / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D008297:Male; D008643:Mesentery / Q000098:blood supply*; D008875:Middle Aged; D009336:Necrosis; D012189:Retrospective Studies; D001619:beta-N-Acetylhexosaminidases
D006596:Hexosaminidases; D054819:Hexosaminidase B; D001619:beta-N-Acetylhexosaminidases