Familial hereditary thrombocytopenia and HLA.
Three generations of a Jewish family with hereditary thrombocytopenia (HT) are described. The disease was manifested clinically by mild bleeding tendency since infancy. Circumcision, however, did not result in excessive bleeding. HLA study in this family indicated that the HT locus is not linked to HLA.
D000328:Adult; D001780:Blood Coagulation Tests; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D004843:Epistasis, Genetic; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D010976:Platelet Count; D013167:Spondylitis, Ankylosing / Q000150:complications; D013921:Thrombocytopenia / Q000150:complications / Q000235:genetics*
D006680:HLA Antigens