Bimolane: structure determination indicates anticancer activity is attributable to ICRF-154.
X-ray diffraction studies of crystals from samples of bimolane synthesized in China and in the United States showed that the crystals consist of the related compound ICRF-154. Analysis of the results of biological tests did not show any significant differences between the anticancer activity of bimolane and ICRF-154. It appears that the anticancer activity of bimolane is due to ICRF-154.
D000970:Antineoplastic Agents / Q000494:pharmacology*; D008958:Models, Molecular; D010879:Piperazines; D011929:Razoxane / Q000031:analogs & derivatives; D014961:X-Ray Diffraction
D000970:Antineoplastic Agents; D010879:Piperazines; C031186:bimolane; D011929:Razoxane; C000283:1,2-bis(3,5-dioxopiperazin-1-yl)ethane