Body weight and dietary factors in Huntington's disease patients compared with matched controls.
A longitudinal study using medical records has confirmed that, even when eating high energy diets, loss of body weight is characteristic of Huntington's disease patients in comparison with a group of matched control subjects. Further analysis showed that although some Huntington's disease patients initially may gain weight rapidly after a period in hospital, they eventually lose weight to below their admission levels. This pattern was not seen in the control group. The findings are discussed in terms of striatal pathology.
D000328:Adult; D000818:Animals; D001835:Body Weight; D003342:Corpus Striatum / Q000503:physiopathology; D004032:Diet; D004038:Diet, Reducing; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006760:Hospitalization; D006801:Humans; D006816:Huntington Disease / Q000178:diet therapy / Q000503:physiopathology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D051381:Rats