[Various indicators of hemostasis and fibrinolysis systems in obese patients on reducing-diet therapy].
In view of setting new criteria of a thrombogenic risk, hemostasis was examined in 96 obesity patients and 30 control subjects. An increase in the fibrinogen level, inhibition of fibrinolytic activity, particularly of XIIa-kallikrein-dependent fibrinolysis were disclosed. No changes in the total blood coagulation activity were recorded. The fasting diet given to the patients for 18-20 days entailed a 12-15 kg weight reduction, fibrinogen level normalization, and fibrinolysis activation. Investigation of antithrombin activity in obesity patients' blood did not reveal any alterations.
D000293:Adolescent; D000328:Adult; D001777:Blood Coagulation; D004038:Diet, Reducing; D005342:Fibrinolysis; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000178:diet therapy
Nekotorye pokazateli sistemy gemostaza i fibrinoliza u bol'nykh ozhireniem pri razgruzochno-dieticheskoĭ terapii.