[Action of hyperthermia on the early radiation reactions of HeLa cells in a stationary growth stage].
A study was made of the influence of hyperthermia (42 degrees C, 30 min) after irradiation with a dose of 6 Gy on the permeability of cell membranes and the rate of incorporation of 3H-thymidine into DNA of HeLa cells at the stationary stage of the culture growth. Hyperthermia was shown to enhance the damaging effect of radiation on cells at this growth stage. It is suggested that this effect is connected with the impaired development of a series of early (during the first minutes and hours) adaptive reactions of HeLa cells, at the stationary stage of growth, to the effect of radiation.
D002463:Cell Membrane Permeability / Q000528:radiation effects; D004247:DNA / Q000096:biosynthesis; D006367:HeLa Cells / Q000528:radiation effects*; D006801:Humans; D006979:Hyperthermia, Induced; D007399:Interphase / Q000528:radiation effects; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
D004247:DNA; D013936:Thymidine
Deĭstvie gipertermii na rannie luchevye reaktsii kletok HeLa statsionarnoĭ stadii rosta.