Callus characteristics following intramedullary nailing with stainless steel or epoxy-carbon nails.
Biological mechanical improvements of osteosynthesis make intramedullary nailing an attractive alternative to bone plate fixation. However, little is known about stress shielding induced by intramedullary implantation of a nail. To evaluate the effect of the nail rigidity on bone healing, mid-metatarsal osteotomies were performed in sheep and fixed with either stainless steel or epoxy-carbon composite V-shaped nails. Mechanical and histomorphometric features of the callus were evaluated 4 months postoperatively. No statistical difference between the two groups were demonstrated for either mechanical or microstructural characteristics. The presence of a fibrous membrane filling the bone/nail interface and allowing sliding micromotions of the implants and the much smaller effect of nail rigidity, as compared to bone plate after implantation, were assumed to be the main reason for this uniformity. At this stage of healing, bone characteristics were more related to a nonspecific (vascular) bone remodeling phenomenon than to a stress-shielding effect.
D000818:Animals; D001696:Biomechanical Phenomena; D001858:Bone Nails / Q000009:adverse effects; D002146:Bony Callus / Q000473:pathology / Q000503:physiopathology*; D004852:Epoxy Compounds / Q000009:adverse effects; D005594:Fracture Fixation, Intramedullary / Q000009:adverse effects; D012756:Sheep; D013193:Stainless Steel / Q000009:adverse effects
D004852:Epoxy Compounds; D013193:Stainless Steel