Idiopathic alveolar hypoventilation in Leber's disease. Unusual sensitivity to mild analgesics and diazepam.
This case history of abnormal sensitivity to ordinary doses of drug with minimal respiratory depressant activities in Leber's disease underlines the fact that patients with this abnormality are exceedingly sensitive to ordinary doses of anaesthetic and sedative drugs.
D000082:Acetaminophen / Q000009:adverse effects*; D000328:Adult; D011431:Dextropropoxyphene / Q000009:adverse effects*; D003975:Diazepam / Q000009:adverse effects*; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D008297:Male; D009896:Optic Atrophy / Q000150:complications*; D012891:Sleep Apnea Syndromes / Q000139:chemically induced*
D004338:Drug Combinations; D000082:Acetaminophen; C011800:acetaminophen, dextropropoxyphene, drug combination; D003975:Diazepam; D011431:Dextropropoxyphene