[Determination of TAA-binding cells in peripheral blood of breast cancer patients (author's transl)].
Circulating human breast tumor-associated antigen (TAA) specific lymphocytes were detected in breast carcinoma patients by antigen specific rosette technique. About 60 percent of patients with breast cancer showed a positive reaction in our test system, the number of rosettes were considerably increased in comparison to the values of blood donors. Following operation normally the number of TAA specific rosettes decrease, contrary, in all cases with recidives, tested, we found positive test results. There is evidence, that our modification of the specific rosette-technique is suitable for detection of malignomas and can be important for the postoperative control of patients with breast carcinoma.
D000951:Antigens, Neoplasm; D001943:Breast Neoplasms / Q000276:immunology*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D012397:Rosette Formation
D000951:Antigens, Neoplasm
Bestimmung von TAA-bindenden Zellen im peripheren Blut von Mammakarzinom-Patienten.