[Radioprotective activity of hypotensive preparations].
In experiments on (CBA X C57B1)F1 mice a study was made of the radioprotective efficiency of some hypotensive drugs. Hemiton administered in different ways, within a wide dose range and at different times before irradiation was shown to possess a pronounced protective action. The substitution of the acid residue in hemiton decreased its activity.
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D003000:Clonidine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005720:Gamma Rays; D008297:Male; D008750:Methyldopa / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011837:Radiation-Protective Agents / Q000494:pharmacology*
D000959:Antihypertensive Agents; D011837:Radiation-Protective Agents; D008750:Methyldopa; D003000:Clonidine
Protivoluchevaia aktivnost' nekotorykh gipotenzivnykh preparatov.