A new cold agglutinin from Achatina fulica snails.
An electrophoretically homogeneous agglutinin was purified from the albumin gland of Achatina fulica snails using asialofetunin-Sepharose 4B as an affinity column. The agglutinin was found to be temperature sensitive; it agglutinated rabbit and human umbilical cord erythrocytes only at low temperature. It was found to be specific for methyl-beta-D-galactoside, and the best inhibitor was N-acetyllactosamine.
D000818:Animals; D002241:Carbohydrates; D002413:Cations, Divalent; D002846:Chromatography, Affinity; D005260:Female; D005312:Fetal Blood; D006384:Hemagglutination; D006388:Hemagglutinins / Q000302:isolation & purification*; D006801:Humans; D011247:Pregnancy; D011817:Rabbits; D012908:Snails / Q000276:immunology*
D002241:Carbohydrates; D002413:Cations, Divalent; D006388:Hemagglutinins