[Wound cleansing with the enzyme combination fibrinolysin/deoxy-ribonuclease].
This clinical investigation was performed to evaluate the therapeutic efficacy of enzymatic wound débridement. Fibrolan (Elase), a combination of fibrinolysin and desoxyribonuclease, was administered in 42 patients with infected accidental or operation wounds. After a treatment over 12 to 14 days all but two wounds showed clean granulation tissue and secondary wound closure could be achieved. There was no sign of adverse drug reaction. A recommendation of this method in the treatment of infected wounds can be given.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003851:Deoxyribonucleases / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005341:Fibrinolysin / Q000627:therapeutic use*; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy; D008875:Middle Aged; D009824:Ointments; D013530:Surgical Wound Infection / Q000188:drug therapy; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000188:drug therapy*
D009824:Ointments; D003851:Deoxyribonucleases; D005341:Fibrinolysin
Erfahrungen bei der Wundreinigung mit der Enzym-Kombination Fibrinolysin/Desoxyribonuklease.