Thyroid autoimmunity in type 2 (non-insulin-dependent) diabetic patients of Caucasoid, black and Mexican origin.
Four hundred and forty-nine patients with Type 2 (non-insulin-dependent) diabetes mellitus and 270 control subjects from Caucasoid, Mexican and black origins were screened for the presence of thyroid microsomal antibodies. Mexican female control subjects had a significantly higher frequency of thyroid microsomal antibodies when compared with black female controls (21% versus 6%, p less than 0.01). Type 2 diabetic patients did not have a higher frequency of thyroid microsomal antibodies when compared with their sex- and race-matched control counterparts. The subgroup of diabetic patients who required insulin for the control of their blood glucose did not have a higher frequency of thyroid microsomal antibodies when compared with non-insulin-requiring diabetic patients. In conclusion autoimmunity against thyroid gland, as manifested by thyroid microsomal antibodies, is not more common in Type 2 diabetic patients when compared with sex- and race-matched control subjects.
D000328:Adult; D001741:Black or African American; D001323:Autoantibodies / Q000032:analysis*; D002140:California; D003924:Diabetes Mellitus, Type 2 / Q000276:immunology*; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008800:Mexico / Q000208:ethnology; D013961:Thyroid Gland / Q000276:immunology*; D044465:White People
D001323:Autoantibodies