[Investigations about the immunobiology of m-proteins of Streptococcus pyogenes. IV. Cell-mediated immunity of rhesus monkeys (Macaca mulatta) against streptococcal antigens (author's transl)].
Cell-mediated immunity was tested in monkeys (Macaca mulatta) immunized with highly purified M-proteins by means of the lymphocyte transformation reaction. Lymphocytes from immunized and nonimmunized monkeys were stimulated with PAL-M-Proteins. IC-M-proteins were completely free of mitogenicity and no lymphocyte stimulation was to be found after immunization with 1.6 mg. Erythrogenic toxins of strain NY5 were able to stimulate lymphocytes of monkeys unspecifically.
D000818:Animals; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000276:immunology*; D002352:Carrier Proteins; D005260:Female; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D008251:Macaca; D008297:Male; D012882:Skin Tests; D013291:Streptococcus / Q000276:immunology
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; C014689:streptococcal M protein
Untersuchungen zur Immunbiologie von M-Proteinen des Streptococcus pyogenes IV. Mitteilung: Zellvermittelte Immunität mit Streptokokkenangigenen ei Rhesusaffen (Macaca mulatta).