Treatment of neurocysticercosis with flubendazole.
Thirteen patients with neurocysticercosis were studied and treated with flubendazole. Diagnostic procedures included computerized tomography (CT) and enzyme-linked immunosorbent assay. In 12 cases treatment with the drug led to clinical improvement. CT showed that some cysts regressed in size, and in two patients they disappeared. The treatment also lowered the antibody levels. The drug was well tolerated and no allergic reaction or other side effects were observed.
D000328:Adult; D000906:Antibodies / Q000032:analysis / Q000134:cerebrospinal fluid; D001562:Benzimidazoles / Q000627:therapeutic use*; D001921:Brain / Q000000981:diagnostic imaging / Q000469:parasitology; D001927:Brain Diseases / Q000188:drug therapy* / Q000209:etiology / Q000469:parasitology; D002648:Child; D003551:Cysticercosis / Q000188:drug therapy* / Q000276:immunology / Q000469:parasitology; D003552:Cysticercus / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008463:Mebendazole / Q000031:analogs & derivatives / Q000627:therapeutic use*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D000906:Antibodies; D001562:Benzimidazoles; D008463:Mebendazole; C018945:flubendazole