The effect of ampicillin on rosette formation between human peripheral blood lymphocytes and SRBC coated with rabbit IgG antibody.
Ampicillin potentiates irreversible dissociation of EAG rosettes observed during incubation of lymphocytes and EAG at 37 degree C. The effect was observed after preincubation with ampicillin or when ampicillin was added to the mixture of lymphocytes and EAG. Both full and T-cell depleted mononuclear leukocytes were affected similarly.
D000667:Ampicillin / Q000494:pharmacology*; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G; D007694:Killer Cells, Natural / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D011817:Rabbits; D011947:Receptors, Antigen, B-Cell; D011961:Receptors, Fc; D012397:Rosette Formation; D012756:Sheep; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D013696:Temperature
D007074:Immunoglobulin G; D011947:Receptors, Antigen, B-Cell; D011961:Receptors, Fc; D000667:Ampicillin