[Effect of hyperthermia and methylprednisolone acetate on circulating thrombocytes in mice].
The effect of microwave-induced whole body hyperthermia and methylprednisolone acetate on the count of circulating thrombocyte in mice was investigated. Mice were heated at 43.5 degree C for 5, 10, 15 or 45 minutes with or without anesthesia. In all cases a high level of thrombocytosis was induced. Such effect was abolished by administration of methylprednisolone acetate 3 hours before heat treatment.
D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000473:pathology*; D005260:Female; D005334:Fever / Q000097:blood*; D008775:Methylprednisolone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000077555:Methylprednisolone Acetate; D051379:Mice; D008815:Mice, Inbred Strains; D010976:Platelet Count; D013997:Time Factors
D000077555:Methylprednisolone Acetate; D008775:Methylprednisolone
Effef de l'hyperthermie et de l'acétate de méthylprednisolone sur la thrombocytémie chez la souris.