ABO blood groups in manic-depressive patients.
The authors compared the ABO blood type distribution pattern of 246 manic-depressive patients to that of 6000 controls. The blood type distribution of all patients did not differ from that of the controls. After subdivision of the patients into subgroups Bipolar I (n = 151) and Bipolar II (n = 95) significant differences were found for blood types O and A between the 2 subgroups, and between the Bipolar II patients and controls. The distribution of blood groups in Bipolar I subgroup did not differ from that of the controls. After division of the patients into 3 diagnostic subgroups (Bipolar-A, n = 30; Bipolar-B, n = 121; Bipolar-C, n = 95) significant differences were found in the distribution of blood groups O and A among the 3 subgroups, and Bipolar-A and Bipolar-C patients also differed from the controls. The results may provide additional support for the subclassification of bipolar major affective disorders into 3 subgroups.
D000017:ABO Blood-Group System; D001714:Bipolar Disorder / Q000097:blood*; D006801:Humans
D000017:ABO Blood-Group System