Intrasellar germinoma associated with hyperprolactinemia.
We report two young adult patients with hyperprolactinemia and neuroendocrine deficits due to predominantly intrasellar germinomas. In both cases the diagnosis of germinoma was confirmed histologically after transsphenoidal surgery. This very rare type of tumor may be intrasellar and it may mimic prolactinoma or craniopharyngioma. Dynamic testing of pituitary function and computed tomography scanning are of value in the early detection of this malignant but radiocurable lesion.
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003397:Craniopharyngioma / Q000175:diagnosis; D004407:Dysgerminoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis; D011388:Prolactin / Q000097:blood*; D012658:Sella Turcica / Q000473:pathology
D011388:Prolactin