Polarographic behaviour and determination of some penicillins after bromometric oxidation.
The direct current polarographic behaviour of the bromometric oxidation product of certain penicillins has been investigated. The oxidized products give a well defined cathodic wave with E1/2 = 0.6 V vs saturated calomel electrode (SCE). The nature of the wave and the electrode reaction have been evaluated. A procedure was developed for investigation of the penicillins either in the pure state or in dosage forms. The results were compared with those obtained with the official methods.
D000667:Ampicillin / Q000032:analysis; D001959:Bromates; D001965:Bromides; D002214:Capsules / Q000032:analysis; D004058:Diffusion; D004563:Electrochemistry; D010084:Oxidation-Reduction; D010406:Penicillins / Q000032:analysis*; D011048:Polarography; D013607:Tablets / Q000032:analysis; D013696:Temperature
D001959:Bromates; D001965:Bromides; D002214:Capsules; D010406:Penicillins; D013607:Tablets; D000667:Ampicillin