Effect of cimetidine on intraocular pressure in patients with glaucoma.
The effect of an intravenous infusion of cimetidine, 2 mg/kg of body weight over 1 hour, on intraocular pressure was studied in four patients with medically controlled glaucoma and compared with the effect of a control infusion of normal saline. Cimetidine, a powerful histamine-H2-receptor antagonist, had no effect on the intraocular pressure in any of the patients.
D000328:Adult; D002927:Cimetidine / Q000494:pharmacology*; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged
D002927:Cimetidine