[Oxygen balance and the effect of antihypoxic preparations in fluorine poisoning].
Long-term inhalations of fluoride at concentrations of 0.58 and 2.75 mg/m3 distrub oxygen regimen in experimental animals (O2 consumption, tension and utilization in the muscle, tissue respiration). During fluorine intoxication, some of the antihypoxic agents (NAD X H, adenine nucleotides, guthimin, bemitil, apressin and glutamic acid) exert a beneficial therapeutic effect. Administration of the glycolysis substrates, NAD, NADP, cytochrome c and sodium hydroxybutyrate, did not exert any marked therapeutic action.
D000818:Animals; D000931:Antidotes / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005458:Fluoride Poisoning / Q000188:drug therapy* / Q000378:metabolism; D006858:Hydrofluoric Acid / Q000506:poisoning; D000860:Hypoxia / Q000517:prevention & control*; D008297:Male; D051379:Mice; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D012969:Sodium Fluoride / Q000506:poisoning; D013997:Time Factors
D000931:Antidotes; D012969:Sodium Fluoride; D006858:Hydrofluoric Acid
Kislorodnyĭ balans i vliianie protivogipoksicheskikh preparatov pri intoksikatsii ftorom.