beta-Hexosaminidase level in serum from patients with viral hepatitis as a measure of reticuloendothelial function.
The lysosomal enzyme beta-hexosaminidase was elevated in different forms of hepatitis. The enzyme level was correlated to the aminotransferases in the acute stage of hepatitis A and B. In hepatitis B there was also a correlation to ALP and bilirubin. In chronic hepatitis B a significant correlation was found only to ALAT. The elevated beta-hexosaminidase levels are attributed to defective non-parenchymal liver cell function in hepatitis.
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006506:Hepatitis A / Q000201:enzymology; D006509:Hepatitis B / Q000201:enzymology; D006525:Hepatitis, Viral, Human / Q000201:enzymology*; D006596:Hexosaminidases / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000503:physiopathology*; D001619:beta-N-Acetylhexosaminidases
D006596:Hexosaminidases; D001619:beta-N-Acetylhexosaminidases