The pharmacokinetics and tumor and neural tissue penetrating properties of SR-2508 and SR-2555 in the dog--hydrophilic radiosensitizers potentially less toxic than misonidazole.
D000284:Administration, Oral; D000818:Animals; D001682:Biological Availability; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D017341:Etanidazole; D005260:Female; D007275:Injections, Intravenous; D007700:Kinetics; D008297:Male; D008920:Misonidazole / Q000008:administration & dosage / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism / Q000662:veterinary*; D009420:Nervous System / Q000378:metabolism*; D009593:Nitroimidazoles / Q000008:administration & dosage / Q000378:metabolism*; D011838:Radiation-Sensitizing Agents; D013329:Structure-Activity Relationship
D009593:Nitroimidazoles; D011838:Radiation-Sensitizing Agents; D017341:Etanidazole; C027710:SR 2555; D008920:Misonidazole