[Influence of synthetic estrogens on experimental Schistosoma mansoni parasitosis in hamsters: cis and trans clomiphene isomers].
Within the framework of previous investigations concerning the protective effect of estrogens during an experimental infection with Schistosoma mansoni in female hamster, the respective actions of the cis and trans forms of clomiphene have been studied. These two forms appear to be unable to assure a protective effect, the mean numbers of parasitic worms and the seric specific antibodies levels which have been observed in the treated animals do not significantly differ from those of the control group.
D000818:Animals; D002996:Clomiphene / Q000494:pharmacology*; D006224:Cricetinae; D064695:Enclomiphene; D005260:Female; D007536:Isomerism; D012550:Schistosoma mansoni / Q000187:drug effects / Q000469:parasitology*; D013329:Structure-Activity Relationship
D002996:Clomiphene; D064695:Enclomiphene
Le rôle des estrogènes de synthèse sur la parasitose expérimentale à Schistosoma mansoni du Hamster: étude des isomères cis et trans du clomifène.