[Fibrinogen and plantar edema induced by lambda carrageenan].
1. Batroxobine which induces fibrinogen consumption, accelerates the development of 48/80 and lambda carrageenan oedema: in the rat the various products released from fibrinogen and fibrin increase these inflammatory reactions. 2. Heparin and epsilon-aminocaproic acid have no influence on carrageenan oedema: the derivatives of fibrinogen do not take part in the constitution of the inflammatory reaction induced by carrageenan. 3. The anti-inflammatory action of this sulfated polygalactose does not depend on its anti-coagulant activity.
D000818:Animals; D012103:Batroxobin / Q000494:pharmacology; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000503:physiopathology*; D005340:Fibrinogen / Q000502:physiology*; D005528:Foot; D006493:Heparin / Q000494:pharmacology; D006614:Hindlimb; D051381:Rats
D002351:Carrageenan; D005340:Fibrinogen; D006493:Heparin; D012103:Batroxobin
Fibrinogène et oedème plantaire provoqué par la carragénine lambda.