Macrophages in the regulation of immunity.
According to the classical view macrophages are prone to ingest and to destruct antigens and intracellular pathogens. More recently it became apparent that macrophages, besides their phagocytic capacities, are involved in the activation and regulation of lymphocyte functions. This article aims to summarize some recent findings on the role of macrophages during the afferent phase of immune responses.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D002450:Cell Communication; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D006801:Humans; D006968:Hypersensitivity, Delayed; D007074:Immunoglobulin G / Q000096:biosynthesis; D008213:Lymphocyte Activation; D008264:Macrophages / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000941:Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D007074:Immunoglobulin G