[Effect of anions on the oxidative phosphorylation and ATPase activity in mitochondria].
Bicarbonate, sulfate and thiocyanate affected distinctly the ADP/O ratio and the rate of oxygen consumption in liver mitochondria. Alterations in the ADP/O coefficient and the ATPase activity were studied in liver and heart mitochondria of control and fasted rats as well as of animals maintained under hypoxy-hypercapnic conditions. Satisfactory correlation was shown between a decrease both in the ADP/O ratio and in sensitivity of ATPase to bicarbonate in liver mitochondria of the animals subjected to these treatments.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology*; D007700:Kinetics; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D013431:Sulfates / Q000494:pharmacology*; D013861:Thiocyanates / Q000494:pharmacology*
D001639:Bicarbonates; D013431:Sulfates; D013861:Thiocyanates; D000244:Adenosine Diphosphate; D000251:Adenosine Triphosphatases
Deĭstvie anionov na okislitel'noe fosforilirovanie i ATF-asnuiu aktivnost' mitokhondriĭ.