Alterations of evoked potentials in the medial lemniscus of the rat due to acute and chronic elevations in blood pressure.
The influence of elevated blood pressure on evoked field potentials in the medial lemniscus induced by peripheral stimulation was studied in the rat. Acute hypertension as a result of phenylephrine infusions reduced the size of this response in individual Wistar Kyoto rats. Chronic renal hypertension in Sprague-Dawley rats also caused a reduction in the dorsal column-medial lemniscal evoked response. These results confirm an inhibitory action of elevated blood pressure on transmission through the dorsal column nuclei.
D000818:Animals; D005073:Evoked Potentials, Somatosensory; D006973:Hypertension / Q000503:physiopathology*; D006977:Hypertension, Renal / Q000503:physiopathology; D008297:Male; D008526:Medulla Oblongata / Q000503:physiopathology*; D009433:Neural Inhibition; D009434:Neural Pathways / Q000503:physiopathology; D051381:Rats; D011919:Rats, Inbred Strains; D013787:Thalamic Nuclei / Q000503:physiopathology*