Agranulocytosis during malaria prophylaxis with Maloprim (pyrimethamine and dapsone).
A case of agranulocytosis during malaria prophylaxis with Maloprim (pyrimethamine and dapsone) is described. At the recommended dose of one tablet weekly this is apparently a rare occurrence but highlights one of the hazards in a changing climate of malarial prophylaxis in which the use of Maloprim is increasing.
D000380:Agranulocytosis / Q000139:chemically induced*; D000962:Antimalarials / Q000009:adverse effects*; D003622:Dapsone / Q000009:adverse effects*; D004338:Drug Combinations / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011739:Pyrimethamine / Q000009:adverse effects*
D000962:Antimalarials; D004338:Drug Combinations; C001678:Maloprim; D003622:Dapsone; D011739:Pyrimethamine