The enkephalin-hydrolytic activity of cerebral and cardiac muscle tissue in Wistar rats with streptozotocin diabetes.
Enkephalin-hydrolytic activity was evaluated in cerebral and cardiac tissue of Wistar rats with experimental streptozotocin-induced diabetes by comparison of the degree of amino acid cleavage from leu-enkephalin in vitro. Ninety days after induction of diabetes the enkephalin-hydrolytic activity was elevated in the cerebral tissue but depressed in the cardiac muscle.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D004743:Enkephalin, Leucine / Q000378:metabolism; D004745:Enkephalins / Q000378:metabolism*; D006868:Hydrolysis; D066298:In Vitro Techniques; D008297:Male; D009130:Muscle, Smooth / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D000596:Amino Acids; D001786:Blood Glucose; D004745:Enkephalins; D004743:Enkephalin, Leucine