Mycoversilin, a new antifungal antibiotic. I. Fermentation, isolation and biological properties.
A new antifungal antibiotic, mycoversilin, was isolated from the culture filtrate of Aspergillus versicolor (N5)17 by repeated column chromatography and recrystallized from ethyl acetate as homogeneous fine needles. Maximum production took place in a medium containing 4% glucose and 1% peptone at pH 3.5, temperature 28 degrees C after 8-9 days of incubation under stationary condition. Mycoversilin is a narrow spectrum antibiotic with activity against filamentous fungi, particularly Trichophyton rubrum (MIC 15 micrograms/ml).
D000935:Antifungal Agents / Q000302:isolation & purification*; D001578:Benzopyrans; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D013997:Time Factors
D000935:Antifungal Agents; D001578:Benzopyrans; C040687:mycoversilin