Changes in ventricular myosin properties during broad breasted white turkey (BBWT) development.
This paper reports the following data with regard to the BBWT cardiovascular system: 1) Arterial Blood pressure progressively increases from 1 to 12 month of age, accompanied by marked left ventricular hypertrophy; 2) The myosin ATPase activity is enhanced about three times; 3) No differences in myosin light chain pattern is observed; 4) The peptide pattern obtained after chymotryptic digestion of the myosin molecule shows that some peptides, which are not evident or barely discernible, in 1 month old animal, are present in the adult one. These findings are surprising because it is well known that the ATPase activity decreases with age and hypertrophy. It is possible that other factors, as the levels of circulating cathecolamines or the thyroid hormones, are involved in the control of myosin synthesis and consequently in its ATPase activity.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001794:Blood Pressure; D004591:Electrophoresis, Polyacrylamide Gel; D006321:Heart / Q000254:growth & development*; D009206:Myocardium / Q000378:metabolism; D009218:Myosins / Q000378:metabolism*; D014422:Turkeys / Q000254:growth & development*
D000251:Adenosine Triphosphatases; D009218:Myosins