Chemically induced autochthonous tumor models in experimental chemotherapy.
Two autochthonous chemically induced tumor models (leukemias and mammary carcinomas) are described. Differences between autochthonous and transplanted tumors with regard to growth kinetics and chemotherapeutic sensitivity are pointed out. The significance of different tumor models for experimental chemotherapy will be discussed.
D000208:Acute Disease; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001943:Breast Neoplasms / Q000473:pathology; D004195:Disease Models, Animal; D006801:Humans; D007938:Leukemia / Q000473:pathology; D007942:Leukemia, Experimental / Q000139:chemically induced / Q000188:drug therapy; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000188:drug therapy; D051381:Rats; D011919:Rats, Inbred Strains
D000970:Antineoplastic Agents