Experimental production of spermatic granuloma in Balb/c mice.
The inflammatory reaction to extravasated spermatozoa was studied in mice by subcutaneous injection of small numbers of such cells. Spermatic granulomata developed several days later, probably as a result of the rather indigestible nature of many spermatozoal components. The granulomata persisted for several days before healing started.
D000818:Animals; D004823:Epididymitis / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000473:pathology*; D007114:Immunization; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D013094:Spermatozoa / Q000276:immunology / Q000473:pathology*