Familial vascular malformations. Report of 25 members of one family.
Vascular malformations are described in 25 members of one affected family. Most of these lesions were cavernous hemangiomas, but arteriovenous malformations and capillary hemangiomas were also microscopically observed in some specimens. The five generation pedigree suggests the vascular malformations are genetically determined on the basis of a dominant inherited trait.
D000293:Adolescent; D000328:Adult; D001165:Arteriovenous Malformations / Q000235:genetics*; D002648:Child; D005153:Facial Neoplasms / Q000235:genetics; D005260:Female; D005799:Genes, Dominant; D006391:Hemangioma / Q000235:genetics; D006392:Hemangioma, Cavernous / Q000235:genetics*; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000235:genetics; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D010375:Pedigree; D012878:Skin Neoplasms / Q000235:genetics