Uptake of 5-hydroxytryptamine by blood platelets in Huntington's chorea and Alzheimer type of presenile dementia.
Kinetics of 5-HT uptake by blood platelets was studied om eleven patients with Huntington's chorea and in ten patients with presenile dementia of Alzheimer type. In both groups of patients 5-HT uptake was unchanged in comparison to that of respective controls of the same age. The results do not confirm earlier reports of an increased 5-HT uptake by blood platelets in Huntington's chorea. Platelet 5-HT uptake does not seem to serve as biological test in either disease.
D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism*; D003704:Dementia / Q000097:blood*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012701:Serotonin / Q000097:blood*
D012701:Serotonin