Combined autoimmune neutro- and thrombocytopenia.
Two children aged 3 and 11 years are described in whom a combined autoimmune neutro-and thrombocytopenia developed in association with pronounced cell-membrane bound IgG. These latter antibodies were detected by the unlabelled immunoperoxidase (PAP) method. Prednisone therapy proved to be beneficial.
D000380:Agranulocytosis / Q000150:complications*; D001327:Autoimmune Diseases / Q000150:complications* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D009503:Neutropenia / Q000150:complications* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000150:complications* / Q000188:drug therapy
D007074:Immunoglobulin G; D011241:Prednisone