Suppressor cells in Hodgkin's disease and lung carcinoma.
Lymphocyte response to PHA was depressed in 9 of 14 cases of Hodgkin's disease (HD) and in 4 of 14 cases of lung carcinoma (LC). This depression was caused in one-third of the HD cases and in one-half of the LC cases by an excess of prostaglandin synthesis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D016861:Cyclooxygenase Inhibitors; D006689:Hodgkin Disease / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D008175:Lung Neoplasms / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008875:Middle Aged; D010835:Phytohemagglutinins / Q000494:pharmacology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D016861:Cyclooxygenase Inhibitors; D010835:Phytohemagglutinins