[Modified evaluation of allergic skin reactions].
Our modified evaluation of the results of investigating experimental allergy includes, apart from the percentage of sensitized animals as in all hitherto applied evaluations, appraisal of "challenge" reactions and results of supplementary in vitro studies in the examined animals' blood. Basing on the formula of the percentage index of the total evaluation of the study - W% = (formula: see text) X100 (a - percentage of sensitized animals; b - index of the total evaluation of reactions intensity, c - results of auxiliary tests in peripheral blood), the effects of allergens were differentiated. Introduction of our own evaluating criteria enabled differentiation of the intensity of effects of the test allergens, which was unfeasible with the hitherto applied Magnusson and Kligman criterion.
D000485:Allergens; D000818:Animals; D003877:Dermatitis, Contact / Q000175:diagnosis*; D004137:Dinitrochlorobenzene / Q000633:toxicity; D004353:Drug Evaluation, Preclinical; D004485:Eczema / Q000139:chemically induced* / Q000175:diagnosis; D004853:Epoxy Resins / Q000633:toxicity; D011192:Potassium Dichromate / Q000633:toxicity; D012882:Skin Tests / Q000379:methods
D000485:Allergens; D004137:Dinitrochlorobenzene; D004853:Epoxy Resins; C009752:epidian; D011192:Potassium Dichromate
Ocena odczynu uczuleniowego skóry we własnej modyfikacji.