Maternal ultrasonography for the antenatal diagnosis of surgically significant neonatal anomalies.
The increased use of ultrasonography in the management and evaluation of pregnancy has provided a unique opportunity to observe the anatomy of the developing fetus from 12 weeks gestation until term. Twenty-eight surgically important anatomic abnormalities have been diagnosed in utero by sonographic examinations at our affiliated institutions over the past three and a half years. These include ascites (five cases), gastroschisis (four cases), omphalocele (three cases), sacrococcygeal teratoma, cystic hygroma, hydrocele, duodenal atresia, multicystic kidney (two cases each), and one each of jejunal atresia, conjoined twins, ureteropelvic junction obstruction, urethral valves, urethral agenesis, and hydronephrosis secondary to reflux. Prenatal diagnosis by ultrasonographic examination has signifcantly improved perinatal management. Elective caesarean section has benefited infants with lesions causing dystocia, such as sacrococcygeal teratoma, omphalocele, and conjoined twins. Advance notification of surgeons and neonatalogists has reduced the delays of postnatal evaluation and treatment that contribute, significantly, to complications and death. In addition, transfer of the pregnant mother carrying an infant with a significant surgical anomaly to a center with facilities for neonatal surgery and specialized postoperative care can be properly planned for in advance. In the near future, intrauterine fetal surgery or palliative intervention may provide increased salvage of patients with obstructive uropathy and diaphragmatic hernia, both of which carry high mortality rates secondary to in utero damage. Sonography has proven useful in following the dilatation of either intestinal or urinary tract structures in utero. In our hands, maternal sonography has improved the surgical care of the newborn and may open a new frontier of intrauterine fetal surgery in the future.
D000009:Abdominal Muscles / Q000002:abnormalities; D000328:Adult; D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D006554:Hernia, Umbilical / Q000175:diagnosis; D006801:Humans; D006869:Hydronephrosis / Q000175:diagnosis; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000175:diagnosis; D008297:Male; D007690:Polycystic Kidney Diseases / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014521:Urethra / Q000002:abnormalities