Acne rheumatism. Report of a case.
A case of acne conglobata with myo-osteoarticular involvement is described. The occurrence of a subacute, symmetrical polyarthritis with radiological changes was the unique feature of this patient. The immunologic work-up demonstrated impairment of delayed hypersensitivity. Control of the systemic symptoms was obtained initially with corticosteroids and during a relapse with indomethacin. Clofazimin was effective in longterm treatment of the acne. Following cessation of all therapy, there has been no evidence of recurrence of either acne or rheumatic symptoms.
D000152:Acne Vulgaris / Q000150:complications* / Q000188:drug therapy; D000293:Adolescent; D001168:Arthritis / Q000150:complications / Q000188:drug therapy; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins; D001799:Blood Sedimentation; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002991:Clofazimine / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007964:Leukocytosis / Q000150:complications; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011859:Radiography; D012216:Rheumatic Diseases / Q000150:complications* / Q000188:drug therapy
D001798:Blood Proteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D002991:Clofazimine; D011241:Prednisone