Serum hyper IgA in diabetes mellitus: I. Increase in the proportion of the polymeric to the monomeric form.
The relative contribution of monomeric and polymeric IgA was investigated in diabetic sera showing that 80-87% of IgA in diabetes are polymeric. A defective mechanism of hepatobiliary transport of IgA is suggested in diabetes mellitus.
D002499:Centrifugation, Density Gradient; D002648:Child; D003920:Diabetes Mellitus / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D046911:Macromolecular Substances; D008875:Middle Aged; D008970:Molecular Weight; D011108:Polymers / Q000032:analysis
D007070:Immunoglobulin A; D046911:Macromolecular Substances; D011108:Polymers