Incidence and significance of micronuclei in pernicious anemia.
The incidence of micronuclei in bone marrow erythroblasts of patients with pernicious anemia ranged between 0.5-5.6% as compared with the value of 0-0.5% noted in hematologically healthy patients. The mechanism of formation and the possible significance of micronuclei in megaloblastic anemia are briefly discussed.
D000752:Anemia, Pernicious / Q000097:blood*; D001853:Bone Marrow / Q000473:pathology; D002467:Cell Nucleus / Q000648:ultrastructure; D002875:Chromosomes / Q000648:ultrastructure; D004900:Erythroblasts / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D006801:Humans; D008938:Mitosis