[T & B-lymphocytes and immunoglobulins of the serum in drug eruptions of immediate type (author's transl)].
Lymphocyte subpopulations and serum immunoglobulins of patients with drug-hypersensitivity were studied. The results are as follows: Lymphocyte subpopulations: decrease of the E-rosette forming cells was observed in both active and symptom free state. The number of IgE-bearing lymphocytes in patients with drug-allergy was higher than that of the controls. Serum-immunoglobulins: The IgE-level in the serum of patients with drug-allergy was higher in active state than afterwards, but still higher than in the controls but it was lower than in atopic dermatitis patients. The level of the other immunoglobulins was normal.
D000293:Adolescent; D000328:Adult; D000632:Aminopyrine / Q000276:immunology; D000707:Anaphylaxis / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D003875:Drug Eruptions / Q000276:immunology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000276:immunology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D007136:Immunoglobulins; D010406:Penicillins; D000632:Aminopyrine; D007073:Immunoglobulin E
T & B-Lymphozyten sowie Serumimmonoglobuline bei Arzneimittelallergien vom Soforttyp.