[Freeze-fracturing study of the ultrastructural changes in the endotheliocytes of the kidney peritubular blood capillaries of white rats in postnatal ontogeny].
Endotheliocytes of peritubular blood capillaries were studied using freeze-etching method in newborn, sexually mature and old rats. The diameter and density of distribution of endothelial fenestrae were shown to increase and the pattern of their distribution underwent changes during postnatal ontogenesis. The old rats were characterized by a high orderliness in distribution of fenestrae which, combined with the near maximal density of fenestrae, led to the appearance of hexagonal symmetry. Progressive hemiarborization of the cytoplasm was the leading tendency during postnatal ontogenesis. A possible role of cytoskeleton in the formation of fenestrae is discussed.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D002196:Capillaries / Q000254:growth & development / Q000648:ultrastructure; D004727:Endothelium / Q000648:ultrastructure; D005614:Freeze Fracturing; D007684:Kidney Tubules / Q000098:blood supply / Q000254:growth & development / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009024:Morphogenesis; D051381:Rats
Kriofraktograficheskoe issledovanie ul'trastrukturnykh izmeneniĭ éndoteliotsitov peritubuliarnykh krovenosnykh kapilliarov pochki belykh krys v postnatal'nom ontogeneze.