[Influence of the catheter-top-position upon the distribution pattern of continuous intra-arterially infused chemotherapeutic agent (author's transl)].
The whole body scanning showed the distribution pattern of infused drug in continuous intra-arterially infused chemotherapy by using a gamma camera and infused RI (99mTc-MAA) from catheter. I measured the whole body scanning counts without shield (A) and with lead shield (B) on ROI and natural back ground counts (BG). Then I calculated the distribution ratio on ROI as following. [(A-B)/(A-BG)] x 100 (%). It was easy to find a certain relation between the catheter-top-position and the distribution ratio. As a result of investigating data, there were about 4 catheter-top-positions in aorta. Case by case, we put the catheter-top in better position and prevented technical side effects and measured roughly total dose on ROI.
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000378:metabolism*; D002404:Catheterization; D006801:Humans; D007261:Infusions, Intra-Arterial; D012709:Serum Albumin; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D014018:Tissue Distribution
D000970:Antineoplastic Agents; D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D013667:Technetium