Results of selective treatment of spina bifida cystica.
The results of selective treatment in 120 infants with open spina bifida, admitted between May 1971 and December 1976, were prospectively studied. Seventy-one infants had adverse criteria at birth and were not treated. They all died, more than 90% of them within 6 months of birth. Seven had meningocele. All were treated and survived without handicap. Forty-two infants with myelomeningocele were actively treated. Thirty-six survive at follow-up after 3 to 9 years. The quality of survival is much better than when selection was not used but 8 children have moderate or severe handicaps. The parents were fully informed and consulted at every decision-making step; they fully supported the principle of selection and the action taken on behalf of their own child.
D006233:Persons with Disabilities; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000150:complications; D007231:Infant, Newborn; D008588:Meningocele / Q000150:complications; D008591:Meningomyelocele / Q000150:complications / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D011446:Prospective Studies