Salicylates and post-tonsillectomy haemorrhage.
A prospective study of 712 patients who had tonsillectomy by guillotine or dissection suggests that salicylates used as post-tonsillectomy analgesia increase the post-operative haemorrhage rate. Paracetamol used as post-operative analgesia was shown to be related to a significantly reduced haemorrhage rate. Guillotine tonsillectomy was not shown to have any adverse effect on the haemorrhage rate.
D000082:Acetaminophen / Q000009:adverse effects / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D010149:Postoperative Pain / Q000188:drug therapy; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D014068:Tonsillectomy / Q000379:methods*
D000082:Acetaminophen; D001241:Aspirin