Adenylate cyclase in the Drosophila memory mutant rutabaga displays an altered Ca2+ sensitivity.
Adenylate cyclase in washed, crude membrane fractions prepared from the Drosophila conditioning mutant, rutabaga, displays an altered responsiveness to Ca2+. The results are of interest since the modulation of adenylate cyclase activity by Ca2+ has recently been suggested to play a role in molecular events that underlie memory formation.
D000067956:Adenylyl Cyclase Inhibitors; D000262:Adenylyl Cyclases / Q000235:genetics / Q000502:physiology*; D000818:Animals; D002118:Calcium / Q000502:physiology*; D002746:Chlorpromazine / Q000494:pharmacology; D004330:Drosophila / Q000502:physiology*; D008568:Memory / Q000502:physiology*; D009154:Mutation; D014268:Trifluoperazine / Q000494:pharmacology
D000067956:Adenylyl Cyclase Inhibitors; D014268:Trifluoperazine; D000262:Adenylyl Cyclases; D002118:Calcium; D002746:Chlorpromazine