Radioimmunoassay of bone morphogenetic protein in serum: a tissue-specific parameter of bone metabolism.
Bone morphogenetic protein (BMP), a paracrine agent inducing cartilage and bone cell differentiation, circulates in the blood and is detectable by BMP radioimmunoassay. Serum BMP levels are higher in growing children and patients with Paget's disease than in normal adults. These observations are interpreted as evidence of a BMP function in the physiology of bone in health and disease.
D000328:Adult; D001798:Blood Proteins; D019485:Bone Morphogenetic Proteins; D001842:Bone and Bones / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D006133:Growth Substances / Q000097:blood*; D006801:Humans; D011863:Radioimmunoassay / Q000379:methods
D001798:Blood Proteins; D019485:Bone Morphogenetic Proteins; D006133:Growth Substances