[Antibacterial spectrum of mezlocillin and MIC/disc correlations (author's transl)].
Mezlocillin is a semi-synthetic antibiotic belonging to the ureidopenicillin group. A study of its activity against a wide range of organisms shows that it is a broad-spectrum antibiotic. However, mezlocillin differs from aminopenicillins and carbenicillin by its activity against numerous strains of klebsiella spp. (modal MIC 4 micrograms/ml). It is also slightly more active than carbenicillin against Pseudomonas spp. (modal MIC 16 micrograms/ml). The regression line relating MICs and disc zone diameters was calculated by the least square method. The correlation coefficient was 0.85.
D000150:Acinetobacter / Q000187:drug effects; D000693:Anaerobiosis; D001419:Bacteria / Q000187:drug effects*; D004755:Enterobacteriaceae / Q000187:drug effects; D008802:Mezlocillin; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
D010406:Penicillins; D008802:Mezlocillin
Spectre général de la mezlocilline et courbe de concordance.