In vitro studies on steroid metabolism by gonadal tissues from ambisexual teleosts. I. Conversion of [14C]testosterone by males and females of the protogynous wrasse Coris julis L.
Gonadal tissue of females, and primary and secondary males of the protogynous wrasse Coris julis were incubated with labeled [14C]testosterone. The large majority of metabolic products consisted of free, neutral steroids. Marked 11 beta-hydroxylation was restricted to testes from secondary males. 5 beta-Reduction of ring A was predominant in both types of males, whereas ovarian tissue from normal females produced a larger share of 5 alpha-androstanes. The metabolic products of ovaries from females that were injected with testosterone 7 days before incubation were similar to those of untreated females, although the ratio of 5 alpha/5 beta reduced steroids was changed toward the "male type".
D000107:Acetylation; D000818:Animals; D005260:Female; D005399:Fishes / Q000378:metabolism / Q000502:physiology*; D006900:Hydroxylation; D008297:Male; D010053:Ovary / Q000378:metabolism*; D012727:Sex Characteristics; D013737:Testis / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism*
D013739:Testosterone