Radiation recall supraglottitis. A hazard in head and neck chemotherapy.
The enhanced effects of chemotherapy on previously irradiated tissue have been well demonstrated. When chemotherapy is given some time after irradiation and elicits a tissue reaction in the radiation field, the reaction is termed radiation recall. We review known interactions between chemotherapy and radiotherapy and report, to our knowledge, the first case of a supraglottitis radiation recall reaction. Familiarity with this phenomenon and potential complications of chemotherapy following head and neck irradiation may expedite early diagnosis and appropriate lifesaving treatment.
D003561:Cytarabine / Q000009:adverse effects* / Q000627:therapeutic use; D004826:Epiglottitis / Q000139:chemically induced* / Q000175:diagnosis; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007827:Laryngitis / Q000139:chemically induced*; D008130:Lomustine / Q000009:adverse effects* / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology*
D003561:Cytarabine; D008130:Lomustine