Properties of the cardiac pacemaker (if) current.
The cardiac pacemaker if current, once thought to be a pure K+ current, is shown to be carried by both Na and K. It is inward and activating during hyperpolarizations negative to -50/-60 mV in normal conditions. Its kinetics are delayed during both activation and deactivation.
D000818:Animals; D004553:Electric Conductivity; D006321:Heart / Q000502:physiology*; D006329:Heart Conduction System / Q000502:physiology*; D007700:Kinetics; D011188:Potassium / Q000378:metabolism; D011690:Purkinje Fibers / Q000502:physiology*; D012964:Sodium / Q000378:metabolism
D012964:Sodium; D011188:Potassium