[Combinations of mezlocillin with other antibiotics. A review of in vitro laboratory studies (author's transl)].
Thirteen publications concerning combinations of mezlocillin with other antibiotics are reviewed, with special attention to antibiotics at present available in France. A fairly large number of different methods were used by the authors, making a comparative study extremely difficult. Most studies dealt with mezlocillin-aminoglycoside combinations against enterobacteriacaea and Pseudomonas aeruginosa : the effect was predominantly synergistic, but a few antagonistic effects are reported. The results on other groups of bacteria and with other antibiotics are more scattered. It was sometimes useful to combine mezlocillin with a cephalosporin. A synergistic effect with fosfomycin was found against Serratia.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004347:Drug Interactions; D004755:Enterobacteriaceae / Q000187:drug effects; D008802:Mezlocillin; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects
D000900:Anti-Bacterial Agents; D010406:Penicillins; D008802:Mezlocillin
Les associations d'antibiotiques avec la mezlocilline. Résultats d'études de laboratoire in vitro.