[Use of a membrane oxygenator with small volumes of perfusion for correction of functional changes in respiration disorders].
Experiments on 11 dogs under hypoventilation hypoxia (a decrease in the respiratory minute volume by 40-50%) were made to study the efficacy of membrane oxygenation using a membrane Sever-OMP oxygenator of the blood under the conditions of minor perfusion (14-17% of the minute volume of circulation). The animals of the main series (7 dogs) with a veno-venous connection of the membrane oxygenator (MO) tolerated hypoxia quite well for 2 hours. The control animals died. The conclusion is made that membrane oxygenation with small volumes of perfusion (with the MO connected according to Seldinger) can be used in conjunction with artificial ventilation where the latter one is not effective enough.
D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D008722:Methods; D010107:Oxygenators, Membrane; D012120:Respiration Disorders / Q000628:therapy*
Ispol'zovanie membrannogo oksigenatora v usloviiakh malykh ob"emov perfuzii dlia korrektsii funktsional'nykh sdvigov pri narushenii dykhaniia.