[Demonstration of the presence of an ultrafiltrable substance in human serum activating somatomedin A].
Human serum contains an ultrafiltrable factor which stimulates the somatomedin activity measured by 35SO4 incorporation into pelvic cartilage of chick embryo, this ultrafiltrable factor activates native serum somatomedin or partially purified somatomedin. The molecular weight determined by fractionated ultrafiltration or chromatography on Biogel P2 is about 350-500 daltons.
D000818:Animals; D002356:Cartilage / Q000187:drug effects / Q000378:metabolism*; D002642:Chick Embryo; D002850:Chromatography, Gel; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007335:Insulin-Like Growth Factor II; D008970:Molecular Weight; D013002:Somatomedins / Q000494:pharmacology* / Q000502:physiology; D013431:Sulfates / Q000378:metabolism*; D014462:Ultrafiltration
D013002:Somatomedins; D013431:Sulfates; D007335:Insulin-Like Growth Factor II
Mise en évidence d'une substance ultrafiltrable dans le sérum humain activant la somatomédine A.