Decreased neutrophil chemotaxis and chronic granulomatous disease.
A case of chronic granulomatous disease associated with decreased neutrophil chemotaxis is described. It is suggested that defective neutrophil motility may be more common than previously recognized in chronic granulomatous disease. However, the presence of a chemotactic defect does not necessarily imply a more severe clinical course.
D002464:Cell Migration Inhibition; D002634:Chemotaxis, Leukocyte; D002675:Child, Preschool; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D009504:Neutrophils / Q000276:immunology