[Hypnogenic properties of the vasoactive intestinal polypeptide in rats].
The intraventricular injection of 100 ng of vasoactive intestinal polypeptide (VIP) is followed by a significant increase of paradoxical sleep in the Rat. In P. chlorophenylalanine pretreated insomniac Rats which do not present spontaneous paradoxical sleep episodes, intraventricular injection of VIP induces normal quantities of this state of sleep.
D000818:Animals; D010134:Fenclonine / Q000037:antagonists & inhibitors; D005768:Gastrointestinal Hormones / Q000494:pharmacology*; D006993:Hypnotics and Sedatives; D008297:Male; D051381:Rats; D012895:Sleep, REM / Q000187:drug effects; D013997:Time Factors; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology*
D005768:Gastrointestinal Hormones; D006993:Hypnotics and Sedatives; D014660:Vasoactive Intestinal Peptide; D010134:Fenclonine
Propriétés hypnogènes du "vasoactive intestinal polypeptide" chez le rat.