[Chromato-mass-spectral study of the secretion in the rabbit small intestine discharged in response to cholera and salmonella toxins].
A study was made of rabbit small intestine secretion induced by cholera and salmonellosis toxins. Application of electron impact mass-spectrometry and chemical ionization permitted identification of 9 and structure assignment for 14 out of 27 secretion components. The assay demonstrated the major part of the components to be the monosaccharides, glucose and galactose. Fatty acids, cholesterol and hydroxyacids were found to be present in negligible amounts. It was discovered that the action of the toxins primarily affected the metabolism of unsaturated fatty acids.
D000818:Animals; D001427:Bacterial Toxins / Q000494:pharmacology*; D002772:Cholera Toxin / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D007419:Intestinal Secretions / Q000032:analysis* / Q000187:drug effects; D007421:Intestine, Small / Q000187:drug effects; D011817:Rabbits; D012475:Salmonella
D001427:Bacterial Toxins; D002772:Cholera Toxin
Khromato-mass-spektral'noe issledovanie sekreta tonkoĭ kishki krolikov, vydeliaemogo pod deĭstviem kholernogo i sal'monelleznogo toksinov.