Leukocyte Enzymes in birth defects- a review.
The utilization of peripheral leukocytes, mixed preparations or specific populations for the detection of homozygous and heterozygous states of inborn errors of metabolism via enzyme assay or detection of accumulated metabolites are reviewed. Additionally, present knowledge of metabolic activities in leukocyte populations and areas of potentially fruitful investigation are discussed.
D000596:Amino Acids / Q000378:metabolism; D050260:Carbohydrate Metabolism; D005492:Folic Acid / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D050356:Lipid Metabolism; D008661:Metabolism, Inborn Errors / Q000097:blood / Q000201:enzymology*; D011687:Purines / Q000378:metabolism; D011743:Pyrimidines / Q000378:metabolism; D014508:Urea / Q000378:metabolism
D000596:Amino Acids; D006025:Glycosaminoglycans; D011687:Purines; D011743:Pyrimidines; D014508:Urea; D005492:Folic Acid