Pentazocine-induced neuromuscular syndromes: clinical, immunological and histopathological studies in two cases.
Two cases of pentazocine-induced neuromuscular syndrome in addicted patients are reported. Histochemical and quantitative histographic analyses of muscle biopsies performed in areas distant from site of injection, disclosed type 2 atrophy. A generalized myotoxic effect of pentazocine is suggested.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007074:Immunoglobulin G / Q000378:metabolism; D007273:Injections, Intramuscular; D008297:Male; D009132:Muscles / Q000201:enzymology; D009133:Muscular Atrophy / Q000139:chemically induced; D009468:Neuromuscular Diseases / Q000139:chemically induced*; D010423:Pentazocine / Q000009:adverse effects*
D007074:Immunoglobulin G; D000251:Adenosine Triphosphatases; D010423:Pentazocine