Rapid expulsion of Trichinella spiralis in suckling rats.
Orally administered Trichinella spiralis muscle larvae were rapidly expelled by rat pups suckling an immune dam. The immunity was delivered in the milk; substantial resistance was conferred on normal rat pups suckled for only 24 hours by a Trichinella-immune foster mother. The pups were protected by oral or systemic administration of specific serum antibodies. When infused into a normal lactating dam, these antibodies accumulated in the serum of her suckling pups.
D000818:Animals; D000833:Animals, Suckling; D000906:Antibodies / Q000276:immunology; D003126:Colostrum / Q000276:immunology; D005260:Female; D007112:Immunity, Maternally-Acquired; D007116:Immunization, Passive; D007411:Intestinal Diseases, Parasitic / Q000276:immunology* / Q000469:parasitology; D007413:Intestinal Mucosa / Q000469:parasitology; D008892:Milk / Q000276:immunology*; D051381:Rats; D014234:Trichinella / Q000276:immunology* / Q000502:physiology; D014235:Trichinellosis / Q000276:immunology* / Q000469:parasitology
D000906:Antibodies