Teratogenic effects of methylnitrosourea on pregnant mice before implantation.
Methylnitrosourea at a dose of 10 mg/kg is teratogenic when applied to pregnant mice on gestational days 2.5, 3.5 or 4.5, but has no such effects on gestational days 0.5 and 1.5.
D000014:Abnormalities, Drug-Induced; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D047108:Embryonic Development / Q000187:drug effects*; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005333:Fetus / Q000033:anatomy & histology; D005865:Gestational Age; D008770:Methylnitrosourea / Q000633:toxicity*; D051379:Mice; D008813:Mice, Inbred ICR; D009607:Nitrosourea Compounds / Q000633:toxicity*; D011247:Pregnancy
D009607:Nitrosourea Compounds; D008770:Methylnitrosourea