Cysticercosis of the central nervous system: clinical and therapeutic considerations.
In a group of forty cases of cysticercosis of the central nervous system, 59% presented with intracranial hypertension due to obstructive hydrocephalus. Ventricular or cisternal cysts, and chronic cysticercus meningitis were the most common causes of hydrocephalus. Seizures occurred in 40% of the patients, in one-half of them in association with CT-detected parenchymatous cysts. In 20% of the cases progressive mental deterioration was the main clinical feature, at times associated with hydrocephalus. CT scan provided the highest diagnostic yield, being abnormal in 90% of cases. Long term prognosis was poor, with a mortality rate of 38% over a 40-month follow-up period. The most common cause of death (60%) was meningitis. CSF shunting is the treatment of choice for hydrocephalus, irrespective of its mechanism. Surgical resection is indicated in some cases with a single superficial (cortical) or posterior fossa cyst. Supratentorial cysts carry a relatively benign prognosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000473:pathology; D002648:Child; D003551:Cysticercosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003704:Dementia / Q000209:etiology; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000209:etiology; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D011559:Pseudotumor Cerebri / Q000209:etiology; D014057:Tomography, X-Ray Computed