Topical deodorized polysulfides. Broadscope acne therapy.
True Vleminckx's solution incorporated in a natural clay-mask vehicle apparently retains its therapeutic qualities while relinquishing all unaesthetic properties. A double-blind, randomized clinical trial comparing the Vleminckx mask to its vehicle was conducted. While the mask vehicle may not be considered a placebo, only the active drug produced a statistically significant reduction in comedone count at the conclusion of the study. The Vleminckx mask achieved a substantially greater reduction in papule count than the vehicle (p less than 0.05). Male and female patients responded positively to the concept of every-other-evening applications of only 20 minutes, as well as to the mask's rapidly astringent and cooling skin effects.
D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D017610:Calcium Compounds; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009812:Odorants; D014677:Pharmaceutical Vehicles; D013440:Sulfides / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013885:Thiosulfates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D017610:Calcium Compounds; D014677:Pharmaceutical Vehicles; D013440:Sulfides; D013885:Thiosulfates; C033907:calcium sulfide; C032915:polysulfide; D002118:Calcium