Peptide interactions with taste receptors: overlap in taste receptor specificity.
Two hitherto unrelated areas of taste appear to provide an important insight into a class of taste receptor sites. A region of the sweet protein monellin is similar to a savory tasting beef octapeptide, and this peptide region could represent an overlap in the specificity of binding to a common peptide taste receptor site. Such an overlap in binding specificity explains the low but significant level of sweetness observed with savory tasting stimuli.
D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D008461:Meat Products; D009842:Oligopeptides / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism; D012970:Sodium Glutamate / Q000378:metabolism; D013329:Structure-Activity Relationship; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000502:physiology*
D009842:Oligopeptides; D010940:Plant Proteins; C002541:monellin protein, Dioscoreophyllum cumminsii; D012970:Sodium Glutamate