Pattern reversal evoked potentials in psychiatric patients.
Elicitation of pattern reversal evoked potentials (PREPs) was added to routine clinical EEG examinations in 100 consecutive adult psychiatric admissions. Latencies and correlations between the peaks and troughs of the triphasic complex were examined with particular reference to current hypotheses about neurophysiologic dysfunctions in schizophrenia and other psychiatric illnesses. PREP data also were examined in relation to age, sex, handedness, concurrent medications, and the clinical EEG findings. The results obtained indicated that age, sex, handedness, neuroleptic and anticholinergic medications and underlying EEG characteristics exert minimal influences upon the PREP. Schizophrenics showed lower hemispheric correlations and greater response stability than did patients with other diagnoses. No lateralized differences in relation to diagnosis were identified.
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D005074:Evoked Potentials, Visual; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D010364:Pattern Recognition, Visual; D011618:Psychotic Disorders / Q000188:drug therapy / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology