Inverse relationship between melanogenesis and endogenous hydroquinone.
Inhibition or stimulation of melanogenesis have been found to occur as a result of the alteration of hydroquinone levels in the body. Substances which stimulate melanogenesis are found to lower the level of hydroquinone in amphibia, and evidence for the relationship is also given by mammalian experiments.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D002025:Bufonidae; D005363:Ficusin / Q000494:pharmacology; D006873:Hydroquinones / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008099:Liver / Q000378:metabolism; D008297:Male; D008543:Melanins / Q000096:biosynthesis*; D009115:Muridae; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000378:metabolism
D006873:Hydroquinones; D008543:Melanins; D005363:Ficusin; D001205:Ascorbic Acid; C031927:hydroquinone