Articular complications of meningococcal meningitis. An immune complex disorder.
A case of noninfectious arthritis was associated with meningococcal meningitis. Elevated levels of immune complexes were demonstrated in both serum and synovial fluid by the C1q binding assay and Raji cell assay. We believe this complication of meningococcal infection is another disorder in which immune complexes may play a pathogenic role.
D000328:Adult; D000936:Antigen-Antibody Complex / Q000302:isolation & purification; D001168:Arthritis / Q000175:diagnosis* / Q000209:etiology; D003172:Complement C1 / Q000302:isolation & purification; D003176:Complement C3 / Q000302:isolation & purification; D004551:Elbow Joint; D005260:Female; D006801:Humans; D007105:Immune Complex Diseases / Q000175:diagnosis* / Q000209:etiology; D008585:Meningitis, Meningococcal / Q000276:immunology*; D013582:Synovial Fluid / Q000276:immunology
D000936:Antigen-Antibody Complex; D003172:Complement C1; D003176:Complement C3