Analysis of the reactive site peptide bond in C1-inhibitor by chemical modification of tyrosyl, lysyl, and arginyl residues: the essential role of lysyl residues in the functional activity of C1-INH.
D001120:Arginine / Q000378:metabolism; D003174:Complement C1 Inactivator Proteins / Q000276:immunology* / Q000302:isolation & purification / Q000502:physiology; D006801:Humans; D008239:Lysine / Q000378:metabolism*; D008298:Maleates / Q000494:pharmacology; D010455:Peptides / Q000378:metabolism*; D010658:Phenylglyoxal / Q000494:pharmacology; D013774:Tetranitromethane / Q000494:pharmacology; D014443:Tyrosine / Q000378:metabolism*
D003174:Complement C1 Inactivator Proteins; D008298:Maleates; D010455:Peptides; D014443:Tyrosine; D001120:Arginine; D013774:Tetranitromethane; D008239:Lysine; D010658:Phenylglyoxal