Demonstration in situ of "T" cells and "T" cell subsets in lichen planus using monoclonal antibodies.
This report describes the in situ demonstration of "T" lymphocytes and "T" lymphocyte subsets in tissue sections using a case of lichen planus as a model. The technique utilized is the indirect immunoperoxidase method with monoclonal antibodies to "T" cells and "T" cell subsets. In the case examined a predominance of helper "T" cells was found. The potential application of this method in the immunopathology of skin and internal organs is discussed.
D000911:Antibodies, Monoclonal / Q000032:analysis*; D000917:Antibody Formation; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000276:immunology* / Q000473:pathology; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000648:ultrastructure
D000911:Antibodies, Monoclonal