[Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs].
Comparative investigations were carried out on the absorption, antianemic action, and growth effect with newborn pigs with FB-82 and dextrofer-100 (an iron dextran complex with 100 mg Fe3+ per cm3) injected i/m. The FB-82 is a combined preparation of 3500000 IU Tylosine tartrate, 0.008 g cyanocobalamin, 0.5 g pyridoxine hydrochloride, 0.1 g tartaric acid, and iron dextran up to 100 cm3 (= 100 mg Fe3+/cm3). Dextrofer-100 enriched with 50 mg Zn, 0.5 mg Co, 200 micrograms cyanocobalamin, and 100 mg pyridoxine hydrochloride for 100 cm3 under the compound name of fericin was also used to compare the anti-anemic effect of FB-82 and dextrofer-100. It was found that FB-82 applied to newborn pigs in a single dose of 2 cm3, i/m, was well absorbed; it developed high concentrations of tylosine in the plasma, and its sideremia and antianemic action were similar to those induced by an equivalent (with regard to iron) amount of dextrofer-100, whereas the result concerning the hematocrit value was better. Compared to dextrofer-100 the FB-82 preparation have better protection to pigs (lowered the mortality rate) and induced better development of the animals. Fericin did not differ essentially from FB-82 in terms of its effect on the red blood picture, however, the percent of protected pigs was lower.
D000042:Absorption; D000747:Anemia, Hypochromic / Q000517:prevention & control / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D004338:Drug Combinations / Q000378:metabolism / Q000627:therapeutic use; D004341:Drug Evaluation / Q000662:veterinary; D006128:Growth / Q000187:drug effects*; D007501:Iron / Q000378:metabolism; D007505:Iron-Dextran Complex / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D007933:Leucomycins / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use*; D011736:Pyridoxine / Q000378:metabolism / Q000627:therapeutic use*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D013997:Time Factors; D015645:Tylosin; D014805:Vitamin B 12 / Q000378:metabolism / Q000627:therapeutic use*
D004338:Drug Combinations; D007933:Leucomycins; C039185:FV 82; D007505:Iron-Dextran Complex; D007501:Iron; D011736:Pyridoxine; D014805:Vitamin B 12; D015645:Tylosin
Sravnitelni izsledvaniia vŭrkhu rezorbtsiiata, protivoanemichnoto deĭstvie i vliianieto vŭrkhu rastezha na FV-82 i dekstrofer-100 pri praseta.