Primary aldosteronism associated with chronic renal failure. Report of a case.
An aldosterone-producing adenoma (APA) was associated with chronic renal failure. Following treatment with Trilostane (a 3 beta-hydroxysteroid dehydrogenase inhibitor), furosemide and continuous ambulatory peritoneal dialysis (CAPD), a left adrenal adenoma was successfully removed. This patient, still being treated with CAPD, is a unique example of primary aldosteronism without showing suppressed plasma renin activity.
D000236:Adenoma / Q000150:complications / Q000628:therapy; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000628:therapy; D003131:Combined Modality Therapy; D013196:Dihydrotestosterone / Q000031:analogs & derivatives / Q000627:therapeutic use; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000209:etiology / Q000628:therapy; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory
D013196:Dihydrotestosterone; D005665:Furosemide; C009954:trilostane