New lessons favoring physicians' support of clinical trials.
The publications of the Hypertension Detection and Follow-up Program and the Multiple Risk Factor Intervention Trial have produced different opinions concerning the therapeutic implications of their results. However, they provide new lessons concerning the design of clinical trials and the ethical implications of this research. Their experiences clearly illustrate the scientific requirements for controlled clinical trials and clarify the ethical validity of future investigations for medical researchers and the medical profession.
D001291:Attitude of Health Personnel; D002986:Clinical Trials as Topic / Q000379:methods / Q000592:standards*; D035061:Control Groups; D003327:Coronary Disease / Q000517:prevention & control; D028663:Ethical Theory; D004992:Ethics, Medical; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000628:therapy; D018579:Patient Selection; D010820:Physicians; D012107:Research Design / Q000592:standards*; D035842:Research Subjects; D012306:Risk