[Effects of hachimijiohgan and ninjintoh on fertility in males with sterility].
The effects of TSUMURA HACHIMIJIOHGAN (TJ-7) and TSUMURA NINJINTOH (TJ-32) on patients with the complaint of male sterility due to both or either oligozoospermia or asthenozoospermia were evaluated in comparison with the effects of clomiphene citrate. TJ-7 was administered in 7.5 g doses three times a day for 4 months to 23 patients with oligozoospermia and 20 patients with asthenozoospermia. Sperm count was improved in 5 of the patients (21%) with oligozoospermia and sperm motility was improved in 10 of the patients (50%) with asthenozoospermia. TJ-32 was administered in 5.1 g doses three times a day for 4 months to 26 patients with oligozoospermia and 20 of the patients with asthenozoospermia. Sperm count was improved in 8 of the patients (31%) with oligozoospermia and sperm motility was improved in 9 of the patients (45%) with asthenozoospermia. Both TJ-7 and TJ-32 were more effective in sperm count and motility than clomiphene citrate. No side effects or abnormal laboratory data including serum LH, FSH, testosterone, estradiol and prolactin were observed in any cases.
D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy*; D008297:Male; D008516:Medicine, Chinese Traditional; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D013081:Sperm Motility / Q000187:drug effects
D010936:Plant Extracts