Presumed BCG infection in a boy with chronic granulomatous disease. A report of a case and a review of the literature.
A male child with chronic granulomatous disease (CGD) developed protracted axillary lymphadenopathy with liquefaction following a bacille Calmettle-Guérin (BCG) immunization. Except for phagocytic dysfunctions characteristic of the underlying disease, immunological examinations were normal. The literature dealing with CGD cases with disseminated BCG infection was reviewed. It is concluded that the possibility of CGD should be considered in those who developed such adverse reactions to BCG immunization.
D001500:BCG Vaccine / Q000009:adverse effects*; D002675:Child, Preschool; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000235:genetics / Q000276:immunology; D006801:Humans; D008199:Lymphadenitis / Q000209:etiology* / Q000276:immunology; D008297:Male; D009504:Neutrophils / Q000276:immunology; D010375:Pedigree
D001500:BCG Vaccine