On the unity of cytomembrane system in the skeletal muscle.
In situ cytochemical evidence for specific Ca-binding sites in the cytomembrane system of skeletal muscle fibers is reported. High Ca accumulation was found at the junctions between different types of cytomembranes. Such junctions might represent "gate-locks" for intracellular Ca movements. Openings of sarcoplasmic reticulum (SR) in frog muscle fibers and of T-tubules in rat muscle fibers are described. Coated and noncoated caveolae were found in rat muscle fibers. The same positive reaction for TPP-ase was found in trans-Golgi zone, terminal cisternae and subsarcolemmal cisternae. These results suggest the membrane continuity and ontogenetic relationships in the cytomembrane system of skeletal muscle fibers.
D000818:Animals; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D006056:Golgi Apparatus / Q000032:analysis / Q000201:enzymology; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000033:anatomy & histology* / Q000378:metabolism* / Q000648:ultrastructure; D010070:Oxalates / Q000494:pharmacology; D011898:Ranidae; D051381:Rats; D012519:Sarcoplasmic Reticulum / Q000032:analysis / Q000378:metabolism
D010070:Oxalates; D002118:Calcium