Characteristics of active sodium and potassium transport in erythrocytes of healthy infants and children.
Erythrocytes were analysed for adenosine triphosphatase (total and sodium-potassium activated) activities, concentrations of sodium and potassium ions and ATP in normal individuals from birth to adulthood age. A decrease of Na+, K+-ATPase activity and an increase of the sodium concentration was seen in infants aged 1-3 and 4-8 months. A decrease of Na+, K+-ATPase was seen during puberty. A correlation was seen between the Na+, K+-ATPase activity and the Na+-K+ ratio. Different influences which might lead to the observed changes in Na+, K+-ATPase activity and erythrocyte sodium concentration are discussed.
D000251:Adenosine Triphosphatases / Q000097:blood; D000255:Adenosine Triphosphate / Q000097:blood; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001692:Biological Transport; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*
D000255:Adenosine Triphosphate; D012964:Sodium; D000251:Adenosine Triphosphatases; D011188:Potassium