[A tissue-specific inhibitor of the cell proliferation of the retinal pigment epithelium in chick embryos].
The salt extract of the nuclear fraction of a homogenate of the retinal pigment epithelium from 12-15 day old chick embryos inhibits selectively the proliferative activity in the retinal pigment epithelium of 3-5 day old embryos. The inhibiting effect of the nuclear factor is found within 20 h after its introduction into the egg. The nuclear extract from the pigment epithelium does not affect the level of proliferation in retina and lens anterior epithelium.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002467:Cell Nucleus / Q000502:physiology; D002642:Chick Embryo; D003864:Depression, Chemical; D010857:Pigment Epithelium of Eye / Q000166:cytology / Q000187:drug effects*; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology*
D014020:Tissue Extracts
Issledovanie tkanespetsificheskogo ingibitora proliferatsii kletok retinal'nogo pigmentnogo épiteliia u kurinykh zarodysheĭ.