[Studies on mixed lymphocyte-tumor cell culture reaction (MLTR) in gynecological malignant tumors by the microplate methods (author's transl)].
For the purpose of observing the cellular immune response to their own tumor cells, MLTR was performed on 16 cases of cervical cancer, 3 cases of corporeal cancer and 6 cases of ovarian cancer. The results of MLTR was presented as a stimulation index (S.I.) by the following formula. (Formula: see text). Results of S.I. were as follows; 1.37 +/- 1.47 in cervical cancer, 0.65 +/- 0.21 in corporeal cancer and 1.12 +/- 0.74 in ovarian cancer. A positive S.I. case which was more than 2.0, was found in 3 cases with cervical cancer (18.8%), in none with corporeal cancer (0.0%) and in 2 with ovarian cancer (33.3%). Thus, the cellular immune response to their autologous tumor cells was considered to be very slight in this assay system.
D005260:Female; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed / Q000379:methods*; D008214:Lymphocytes / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000276:immunology*; D014594:Uterine Neoplasms / Q000276:immunology*