Anomalous diffusion of erythrocytes in the presence of polyvinylpyrrolidone.
The diffusion coefficient of erythrocytes was measured using quasi-elastic light-scattering (QELS) techniques. The cells were suspended in phosphate-buffered saline solutions with and without a macromolecule, polyvinylpyrrolidone (PVP[360]). In the presence of the PVP(360) an anomalously high diffusion coefficient was measured for metabolizing cells with a normal transmembrane potential. The results are in agreement with experiments on rouleau formation by red blood cells and are supportive of the hypothesis of a long-range coherent interaction between metabolically active biological cells.
D002465:Cell Movement / Q000187:drug effects; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008027:Light; D011205:Povidone / Q000494:pharmacology*; D012542:Scattering, Radiation
D011205:Povidone