Allergic complication in operated gastroduodenal ulcers: pathogeny and morphoclinical significance.
1660 gastric and duodenal ulcers were examined, of which 61 per cent showed allergic complications. The eosinophilic infiltrate associated with endarteritis and fibrinoid necrosis in the area, more accentuated than in ulcers without eosinophils is produced through a mechanism of atopic hypersensitization to food antigens. A more frequent appearance of allergic complications in the gastrointestinal tract explains why some ulcers do not heal and why certain groups of food tolerated by some patients, are rejected by others. It also imposes in some cases a desensitization treatment concomitantly with the antiulcerous one.
D004804:Eosinophils / Q000503:physiopathology / Q000648:ultrastructure; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D010437:Peptic Ulcer / Q000150:complications* / Q000473:pathology / Q000601:surgery; D011184:Postoperative Period