Lack of in vitro activity of cefoxitin, cefamandole, cefuroxime, and piperacillin against Chlamydia trachomatis.
Newer penicillins and cephalosporins are being evaluated in many infections. One of these infections, acute pelvic inflammatory disease, can be caused by Chlamydia trachomatis. This study demonstrated that cefoxitin, cefamandole, cefuroxime, and piperacillin had no effective in vitro activity against C. trachomatis.
D002435:Cefamandole / Q000494:pharmacology; D002440:Cefoxitin / Q000494:pharmacology; D002444:Cefuroxime / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D002692:Chlamydia trachomatis / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D010878:Piperacillin
D002511:Cephalosporins; D010406:Penicillins; D002435:Cefamandole; D002440:Cefoxitin; D002444:Cefuroxime; D010878:Piperacillin