Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?
Treatment with thioridazine resulted in hyperpyrexia and ventricular tachycardia in a young woman who was later shown to have thyrotoxicosis. The reasons why hyperthyroidism may enhance thioridazine toxicity are reviewed.
D000328:Adult; D005260:Female; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy; D013610:Tachycardia / Q000139:chemically induced*; D013881:Thioridazine / Q000009:adverse effects*
D013881:Thioridazine