Allergic contact dermatitis from laboratory synthesis of 4-bromomethyl-6,8-dimethyl-2(1H)-quinolone.
A case is reported of allergic contact dermatitis from 4-bromoacetoacet-2,4-dimethylanilide and 4-bromomethyl-6,8-dimethyl-2(1H)-quinolone in a 19-year-old chemical laboratory technician. The relationship between the chemical reactivity of these compounds and their sensitizing potential is discussed.
D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D005260:Female; D006801:Humans; D010328:Patch Tests; D011804:Quinolines / Q000009:adverse effects* / Q000138:chemical synthesis; D015363:Quinolones
D011804:Quinolines; D015363:Quinolones; C031176:4-bromomethyl-6,8-dimethyl-2(1H)-quinolone