Abnormal calcium metabolism in hemodialyzed patients with diabetic nephropathy.
Calcium metabolism was studied in hemodialyzed patients with diabetes mellitus nephropathy (HD/DM) and in hemodialyzed nondiabetic patients with chronic glomerulonephritis (HD/non-DM). Incidence of bone changes visible in X-ray films, assessed by changes in the lamina dura and trabecular patterns of mandibulae, was less in HD/DM than in HD/non-DM patients. Serum c-terminal parathyroid hormone was significantly lower in HD/DM than that in HD/non-DM. Serum calcitonin was higher in HD/DM than that in HD/non-DM. The lower level of c-terminal parathyroid hormone would be a reason that bone changes were less in HD/DM than in HD/non-DM patients.
D000293:Adolescent; D000328:Adult; D002116:Calcitonin / Q000097:blood; D002118:Calcium / Q000378:metabolism*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000378:metabolism*; D003928:Diabetic Nephropathies / Q000378:metabolism* / Q000628:therapy; D005260:Female; D005921:Glomerulonephritis / Q000378:metabolism; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism* / Q000628:therapy; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000378:metabolism; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D011859:Radiography; D006435:Renal Dialysis
D010281:Parathyroid Hormone; D002116:Calcitonin; D002118:Calcium