A clinical technique for prevention of spasm and preservation of endothelium in saphenous vein grafts.
Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 degrees C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure. This technique preserves endothelial integrity in human reversed saphenous vein grafts.
D001807:Blood Vessel Prosthesis; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010208:Papaverine / Q000627:therapeutic use; D012501:Saphenous Vein / Q000601:surgery*; D013035:Spasm / Q000517:prevention & control*; D013523:Surgical Equipment
D010208:Papaverine