[Intolerance to spironolactone in refractory cardiac insufficiency. Probable changes in the aldosterone receptors. Study of 11 cases].
D000293:Adolescent; D000328:Adult; D001145:Arrhythmias, Cardiac / Q000209:etiology; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology; D006947:Hyperkalemia / Q000209:etiology; D007010:Hyponatremia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid / Q000378:metabolism*; D012083:Renin / Q000097:blood; D013148:Spironolactone / Q000009:adverse effects* / Q000378:metabolism / Q000627:therapeutic use
D011965:Receptors, Glucocorticoid; D018161:Receptors, Mineralocorticoid; D011987:Receptors, Steroid; D013148:Spironolactone; D012083:Renin
Intolerancia a la espironolactona en la insuficiencia cardíaca refractaria. Probable alteración de los receptores de la aldosterona. Estudio de 11 casos.