The effect of vagolytic drugs on airway obstruction in patients with bronchial asthma.
Atropine sulphate and ipratropium bromide (Atrovent, Sch-1000 were found to be potent bronchodilators free from significant side effects. Their action was similar in magnitude to the one produced by salbutamol. Both drugs were particularly effective at the level of the large airways.
D000402:Airway Obstruction / Q000150:complications / Q000188:drug therapy*; D000420:Albuterol / Q000627:therapeutic use; D001249:Asthma / Q000150:complications / Q000188:drug therapy*; D001285:Atropine / Q000627:therapeutic use; D005541:Forced Expiratory Volume; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use; D008450:Maximal Midexpiratory Flow Rate; D010276:Parasympatholytics / Q000627:therapeutic use*
D010276:Parasympatholytics; D001285:Atropine; D009241:Ipratropium; D000420:Albuterol