Sensitivity of Kr-81m and Xe-127 in evaluating nonembolic pulmonary disease.
The relative sensitivities of Kr-81m and Xe-127 in detecting lung ventilation defects was evaluated in 80 patients with nonembolic pulmonary diseases. Krypton-81m ventilation images (500,000 count) were interdigitated with Tc-99m MAA perfusion images; both were compared with Xe-127 images. The distributions of the two gases were also compared on the basis of point-by-point computer analyses. Xenon-127 was found to be more sensitive than Kr-81m in clinical evaluations of scintiphotos--although they were equivalent by computer analyses--in indicating regions of impaired ventilation in patients with obstructive airways disease.
D003201:Computers; D006801:Humans; D007726:Krypton; D008173:Lung Diseases, Obstructive / Q000000981:diagnostic imaging*; D008875:Middle Aged; D011655:Pulmonary Embolism; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012709:Serum Albumin; D013667:Technetium; D013668:Technetium Tc 99m Aggregated Albumin; D014692:Ventilation-Perfusion Ratio; D014980:Xenon Radioisotopes
D011868:Radioisotopes; D012709:Serum Albumin; D013668:Technetium Tc 99m Aggregated Albumin; D014980:Xenon Radioisotopes; D007726:Krypton; D013667:Technetium