The physico-chemical properties of cancer-suppressive factor.
Biological fluids of mammalia possess a cancer-suppressive activity. CSF has been isolated from ascitic fluid (Ehrlich ascites carcinoma) in this laboratory. Chemically, it is a peptide complexing with lipids, and inhibits the cancer cells in vitro, but has a little effect on normal bone marrow cells. This paper reports the molecular homogeneity, amino acid composition, approximate molecular weight and terminal structures of the peptide.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000970:Antineoplastic Agents / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D007166:Immunosuppressive Agents / Q000032:analysis*; D008970:Molecular Weight; D011506:Proteins / Q000032:analysis*
D000596:Amino Acids; D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D011506:Proteins; C034911:serum cancer-suppressive peptide, mouse