[Noninvasive first-pass study of the heart with the short-lived radionuclide gold 195m].
The new shortlived radionuclide Aurum 195 m (T1/2: 30.5 sec) has been used for 1,596 first-pass examinations of 792 patients. During first-pass the same maximum count rates of an average of 300,000 cts/sec and after background subtraction the same enddiastolic counts over the left ventricle averaging 10,000 cts/sec can be achieved as with the previously used Tc-99 m pertechnetate injections. The short half-life and fast regeneration of Au-195 m within 3 minutes allow repeated, subsequent injections with significant reduction in radiation exposure. Half of the studies were done at rest and exercise, one third in two oblique projections, RAO and LAO. Examinations in two projections improve the information facilitating the localization of ischemic or infarcted LV-regions particularly with respect of septal and/or lateral extension. Strictly lateral dysfunction may sometimes be only recognizable in the second LAO-projection. The RAO-view best discriminates the extension along the anterior and infero-posterior wall.
D005069:Evaluation Studies as Topic; D006050:Gold Radioisotopes; D006207:Half-Life; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008722:Methods; D005082:Physical Exertion; D011829:Radiation Dosage; D011876:Radionuclide Generators; D011877:Radionuclide Imaging; D012146:Rest; D013997:Time Factors
D006050:Gold Radioisotopes
Nichtinvasive First Pass-Untersuchung des Herzens mit dem kurzlebigen Radionuklid Aurum 195m.