[Synchronization of proliferating cells in the liver, gastric glands and duodenum].
Multiple injections (5-6 times) of hydroxyurea to hepatectomized rats lead to synchronization of 78% of proliferating cells in the regenerating liver. The amount of DNA-synthesizing cells of the foveolar epithelium of the pyloric glands of the gastric mucosa increases 2.7-fold, the proliferation in slowly renewing Brunner glands of the duodenum is dramatically activated.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis; D004386:Duodenum / Q000166:cytology* / Q000187:drug effects; D005753:Gastric Mucosa / Q000166:cytology* / Q000187:drug effects; D006498:Hepatectomy; D006918:Hydroxyurea / Q000494:pharmacology; D008099:Liver / Q000166:cytology* / Q000187:drug effects; D008115:Liver Regeneration / Q000187:drug effects; D008297:Male; D008940:Mitotic Index / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D004247:DNA; D006918:Hydroxyurea
Sinkhronizatsii proliferiruiushchikh kletok pecheni, zhelez zheludka i dvenadtsatiperstnoĭ kishki.