Malignant external otitis. Cure with adjunctive hyperbaric oxygen therapy.
Malignant otitis externa developed in a 55-year-old man with diabetes. This Pseudomonas aeruginosa infection was refractory to high-dose moxalactam disodium therapy, despite sufficient in vitro tube dilution sensitivity results. When adjunctive hyperbaric oxygen therapy was added to the treatment regimen, the infection resolved.
D002513:Cephamycins / Q000627:therapeutic use; D048909:Diabetes Complications; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D009070:Moxalactam; D010032:Otitis Externa / Q000188:drug therapy / Q000628:therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000628:therapy*
D002513:Cephamycins; D009070:Moxalactam