[Clinical studies of cefoperazone in pediatric field (author's transl)].
Clinical studies of cefoperazone (CPZ) were performed and the following results were obtained. 1) CPZ was intravenously administered at the daily dose of 35 approximately 107 mg/kg to 10 children with infection: urinary tract infection (6 cases), respiratory infection (3 cases), and acute enterocolitis (1 case). The overall efficacy rate was 80%, and in urinary tract infection including one case caused by Pseudomonas aeruginosa, efficacy rate was 100%. 2) The bloody stools were noted in one case, 2 days after the administration of CPZ, but improved gradually. No abnormal laboratory data were found.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001424:Bacterial Infections / Q000188:drug therapy*; D002438:Cefoperazone; D002511:Cephalosporins / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy
D002511:Cephalosporins; D002438:Cefoperazone