Clinical significance of lipoprotein-X in congenital biliary atresia.
Quantitative lipoprotein-X (Lp-X) was measured for diagnostic and postoperative examination of congenital biliary atresia (CBA). There was no significant difference in the levels in children with CBA (n = 23) or neonatal hepatitis (NH) (n = 14). However, a value over 200 mg/dl was found in 7 of CBA but not NH patients. As to 13 postoperative non-icteric patients with CBA, Lp-X was absent in only 2 patients. Thus, postoperative patients without jaundice do not always have a normal biliary secretion. From those results, estimation of Lp-X is both useful for diagnosis and postoperative evaluation of CBA.
D001652:Bile Ducts / Q000002:abnormalities* / Q000601:surgery; D002675:Child, Preschool; D002779:Cholestasis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006505:Hepatitis / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008073:Lipoprotein-X / Q000097:blood*; D008111:Liver Function Tests; D008297:Male; D010743:Phospholipids / Q000097:blood; D011184:Postoperative Period
D008073:Lipoprotein-X; D010743:Phospholipids