[Influence of the GABAergic system on eating behavior induced by the tail pinching technic in rats].
The present experiment was undertaken to investigate the possible involvement of GABAergic neurons in the regulation of the feeding behavior induced by tail pinching. Injections before the tail pinching of gamma-aminobutyric acid (GABA) agonist (Muscimol: 570 micrograms.kg-1 i.p. 20 min before testing), GABA antagonist (Picrotoxine: 1,5 mg.kg-1 i.p. 30 min before testing) and a GABA transaminase inhibitor (Acetate dipropyle: 200 mg.kg-1 i.p. 40 min before testing) have no effects on the ingestion of sweet milk. These preliminary results provide support for the hypothesis that the feeding behavior induced by TP is not mediated through GABAergic system.
D000818:Animals; D002149:Energy Intake; D005247:Feeding Behavior / Q000187:drug effects*; D006801:Humans; D008297:Male; D009118:Muscimol / Q000494:pharmacology*; D010080:Oxazoles / Q000494:pharmacology*; D010852:Picrotoxin / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological; D014635:Valproic Acid / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D009118:Muscimol; D010080:Oxazoles; D010852:Picrotoxin; D014635:Valproic Acid; D005680:gamma-Aminobutyric Acid
Influence du système GABAergique sur le copmportement alimentaire induit par la technique de pincement de la queue (tail-pinching ou T.P.) chez le rat.