Bipolar affective disorder, lithium carbonate and Ca++ ATPase.
Erythrocyte membrane Ca++ ATPase levels were investigated in 10 men treated with lithium carbonate for bipolar affective disorder. With regard to Ca++ ATPase activity, which is intimately associated with the active Ca++ transport mechanism of the red cell membrane, it is interesting to note that the Ca++ ATPase activities of bipolar disorder patients were found to be depressed at 2 hours after the administration of lithium. These data are discussed in terms of the physiology of bipolar affective disorder and lithium carbonate.
D000328:Adult; D001692:Biological Transport; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000201:enzymology; D000252:Calcium-Transporting ATPases / Q000097:blood*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D008094:Lithium; D000252:Calcium-Transporting ATPases