Iopromide. A new non-ionic contrast medium.
The new non-ionic contrast agent, iopromide (Schering) is comparable in osmolality and viscosity to the other recently developed low osmolality media, ionic and non-ionic. Its chemotoxicity, as assessed by protein binding, enzyme inhibition and effects on the coagulation cascade is significantly less than that of the conventional media and very similar to that of another established new non-ionic agent, iopamidol (Niopam, Bracco/Merck).
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002800:Cholinesterase Inhibitors; D003287:Contrast Media / Q000097:blood / Q000633:toxicity*; D006801:Humans; D007463:Iodobenzoates / Q000633:toxicity*; D007472:Iohexol / Q000031:analogs & derivatives*; D007479:Iopamidol; D007483:Iothalamic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D007485:Ioxaglic Acid; D007928:Lethal Dose 50; D051379:Mice; D011485:Protein Binding; D013918:Thrombin Time; D014283:Triiodobenzoic Acids / Q000097:blood / Q000494:pharmacology / Q000633:toxicity*
D002800:Cholinesterase Inhibitors; D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007483:Iothalamic Acid; D007472:Iohexol; C038192:iopromide; D007479:Iopamidol; D007485:Ioxaglic Acid