[Synthesis and biological activity of new compounds with the 1,3-dioxol(4,5-g)quinoline structure].
The synthesis of some 1,3-dioxol[4,5-g]quinoline derivatives is described. The compounds show appreciable activity in vitro against some gram-positive bacteria and do not show any significant activity against P388 lymphocytic leukemia. Microbiological and antitumor results are presented.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004149:Dioxoles / Q000138:chemical synthesis*; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D011804:Quinolines / Q000138:chemical synthesis*
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D000981:Antiprotozoal Agents; D004149:Dioxoles; D011804:Quinolines
Sintesi ed attività biologica di nuovi composti a struttura 1,3-diossol[4,5-g]chinolinica.