The effects of duodenal glucose and dextrin infusion on adipose tissue metabolism in sheep.
Three groups of 3 sheep were penned individually and provided with pelleted dried grass. In addition two of the groups received either dextrin or glucose via duodenal cannulae. The rate of in vitro lipogenesis, from acetate of glucose, in subcutaneous adipose tissue was significantly increased in the carbohydrate-infused sheep. The increase in lipogenesis in response to glucose infusion was much greater than that to dextrin infusion. The changes in lipogenesis induced by dextrin or glucose infusion were reflected in the specific activities of the various lipogenic enzymes examined. These results are discussed in relation to the capacity of the sheep small intestine to hydrolyse alpha-linked glucose polymer.
D000085:Acetates / Q000378:metabolism; D000273:Adipose Tissue / Q000201:enzymology / Q000378:metabolism*; D000818:Animals; D003912:Dextrins / Q000008:administration & dosage / Q000494:pharmacology*; D004386:Duodenum / Q000378:metabolism*; D005947:Glucose / Q000008:administration & dosage / Q000494:pharmacology*; D008055:Lipids / Q000096:biosynthesis*; D008297:Male; D012756:Sheep / Q000378:metabolism*; D013213:Starch / Q000494:pharmacology*
D000085:Acetates; D003912:Dextrins; D008055:Lipids; D013213:Starch; D005947:Glucose