Pentamidine-induced diabetes mellitus.
Twelve cases of diabetes mellitus following pentamidine isethionate ( Lomidine ) treatment for antimonial -resistant cases of kala-azar are reported. 11 were found to be insulin-dependent and one insulin-independent. One patient died at home two months later and the rest still had diabetes mellitus at follow-up after two to five years.
D000578:Amidines / Q000009:adverse effects*; D003920:Diabetes Mellitus / Q000139:chemically induced*; D003922:Diabetes Mellitus, Type 1 / Q000139:chemically induced; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000188:drug therapy; D010419:Pentamidine / Q000009:adverse effects* / Q000627:therapeutic use
D000578:Amidines; D010419:Pentamidine