Immunological traits in generations 7 to 12 of two lines of Japanese quail selected for high or low antibody response to Newcastle disease virus.
Several immunological traits were compared in lines of Japanese quail selected for high and low secondary immune responses to anti-Newcastle disease virus (NDV). The high line of quail, selected for high ability to produce antibodies, was more responsive in both their primary response to NDV antigen used in the selection as well as to other antigens used in selection process including NDV (Ishi strain), tissue culture-derived Newcastle disease (TCND strain), NDV strain B1, influenza virus, sheep erythrocytes, and Salmonella pullorum than the low line, selected for low ability to produce antibody titers. Mitogenic response to phytohemagglutinin mitogen in the blood lymphocytes from high line quail was more reactive than those from low line quail. Significant line differences were also found in the number of spontaneous rosette cells produced by blood lymphocytes with both fowl and rabbit erythrocytes; the number in the high line exceeded those in the low line.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D000914:Antibodies, Viral / Q000096:biosynthesis*; D001947:Breeding; D003370:Coturnix / Q000235:genetics* / Q000276:immunology; D005260:Female; D014644:Genetic Variation; D007109:Immunity; D008213:Lymphocyte Activation; D008297:Male; D009522:Newcastle disease virus / Q000276:immunology*; D009975:Orthomyxoviridae / Q000276:immunology; D011784:Quail / Q000235:genetics*; D012397:Rosette Formation; D012475:Salmonella / Q000276:immunology
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral