Mycoflora in bronchial asthma.
Examinations were done in 22 patients suffering from bronchial asthma and 10 patients with acute respiratory infection (control group). In all cases quantitative mycological and bacteriological sputum tests, mycoserological tests and cutaneous tests were performed. Presence of C. albicans was evident in 90% of sputum from asthmatics with proliferation in 45% of cases (10(4) or more of yeast cells/ml of sputum). The proliferation of the mould fungi in the sputum was not observed. Allergization with C. albicans was encountered in 25% of asthmatics and allergization with mould fungi in 36% of them. Mycoserological tests were reliable when the autoantigens of the patients flora were used. The studies of the control group call attention to possible accompanying acute invasions of C. albicans in the early days of primary acute respiratory tract infection.
D001249:Asthma / Q000382:microbiology*; D001419:Bacteria / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000276:immunology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008172:Lung Diseases, Fungal / Q000276:immunology* / Q000382:microbiology; D013183:Sputum / Q000382:microbiology*