A comparative study of ectopic production of human chorionic gonadotropin and human chorionic somatotropin by carcinoma of the uterine cervix.
A comparative study was made on the ectopic production of chorionic gonadotropin (hCG) and chorionic somatotropin (hCS) by carcinoma of the uterine cervix. Incidence of hCG in the sera of cancer patients was much higher than hCS. hCS has a better prospect in early detection of cancer cervix than hCG. All hCS-producing tumors and the majority of hCG-producing ones were histologically diagnosed as squamous cell carcinoma. The source of hCG and hCS were found to be the tumor cells. A fall or disappearance of detectable hCG and hCS was noted following surgery or radiotherapy.
D000230:Adenocarcinoma / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000378:metabolism; D006063:Chorionic Gonadotropin / Q000096:biosynthesis*; D005260:Female; D013006:Growth Hormone / Q000096:biosynthesis*; D006801:Humans; D009367:Neoplasm Staging; D010928:Placental Lactogen / Q000032:analysis; D002583:Uterine Cervical Neoplasms / Q000378:metabolism* / Q000532:radiotherapy / Q000601:surgery
D006063:Chorionic Gonadotropin; D013006:Growth Hormone; D010928:Placental Lactogen