Acquired hypogammaglobulinaemia and sarcoidosis.
A syndrome has been described in which hypogammaglobulinaemia is associated with splenomegaly and haemolytic anaemia and also non-caseating granulomata in lymph nodes, liver, spleen and skin. This report describes a patient with this syndrome who in addition had a positive Kveim and elevated serum angiotensin converting enzyme (SACE), suggesting the diagnosis of sarcoidosis.
D000361:Agammaglobulinemia / Q000150:complications*; D000368:Aged; D000743:Anemia, Hemolytic / Q000150:complications*; D005260:Female; D006801:Humans; D012507:Sarcoidosis / Q000150:complications*; D014605:Uveitis / Q000150:complications