Tetrachloroazobenzene in 3,4-dichloroaniline and its herbicidal derivatives: propanil, diuron, linuron, and neburon.
The presence of 3,3', 4,4'-tetrachloroazobenzene (TCAB) was determined by high performance liquid chromatography in 3, 4-dichloroaniline and herbicides made therefrom. The concentrations of TCAB in 3, 4-dichloroanilines and in different herbicides from a variety of manufacturers ranged from 9 to 1400 micrograms/g (ppm). The chloracnegenic potential of these products, as determined by rabbit ear test, suggests that it is in the same range of 2, 3, 7, 8-tetrachlorodibenzodioxin, a known potent chloracnegenic agent.
D000152:Acne Vulgaris / Q000139:chemically induced; D000814:Aniline Compounds / Q000032:analysis*; D000818:Animals; D001391:Azo Compounds / Q000032:analysis*; D002722:Chlorobenzenes / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004237:Diuron / Q000032:analysis; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006540:Herbicides / Q000032:analysis* / Q000633:toxicity; D007642:Keratosis / Q000139:chemically induced; D008044:Linuron / Q000032:analysis; D010671:Phenylurea Compounds / Q000032:analysis; D011411:Propanil / Q000032:analysis; D011817:Rabbits
D000814:Aniline Compounds; D001391:Azo Compounds; D002722:Chlorobenzenes; D006540:Herbicides; D010671:Phenylurea Compounds; D008044:Linuron; C013279:3,4,3',4'-tetrachloroazobenzene; C014464:3,4-dichloroaniline; C028818:neburon; D011411:Propanil; D004237:Diuron