[The effects of progesterone and androgens on in vitro metabolism of human placenta from early pregnancy (author's transl)].
The effects of progesterone, testosterone and dehidroisoandrosterone on oxygen consumption, aerobic CO2-production and anaerobic glycolysis of human placentas from early pregnancy were studied. Oxygen consumption and anaerobic glycolysis were reduced by progesterone and dehidroisoandrosterone. Testosterone inhibits oxygen consumption first off all, while moderately decreases CO2 production in aerobic environment.
D002245:Carbon Dioxide / Q000378:metabolism; D003687:Dehydroepiandrosterone / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects*; D006019:Glycolysis / Q000187:drug effects; D006801:Humans; D010101:Oxygen Consumption / Q000187:drug effects; D010920:Placenta / Q000187:drug effects* / Q000378:metabolism; D011374:Progesterone / Q000494:pharmacology*; D013739:Testosterone / Q000494:pharmacology*
D002245:Carbon Dioxide; D013739:Testosterone; D003687:Dehydroepiandrosterone; D011374:Progesterone
Uber die Wirkung von Progesteron und Androgenen auf den in vitro Stoffwechsel der menschlichen Frühplacenta.