[Early post-prandial hyperglycemic response: from case reports of insulin-dependent diabetics evaluated with an artificial pancreas].
In order to define the after-meal glycaemic response in diabetic subjects, we studied it in 20 insulin-dependent diabetic patients by automatic control using artificial beta-cell. We observed a different behaviour of blood glucose and of the consequent insulin requirement at the meals: in two subjects an early and excessive rise of blood glucose values at the meal was shown, not rapidly normalizable by artificial beta-cell. It should support, in our opinion, in these subjects, an increased neuro-entero-hormonal activity on endocrine pancreas production and a subsequent enhancement of hepatic glucose output.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D005260:Female; D005502:Food; D006801:Humans; D007332:Insulin Infusion Systems; D008297:Male; D013997:Time Factors
D001786:Blood Glucose
Risposta iperglicemica post-prandiale precoce: da una casistica di soggetti diabetici insulino-dipendenti valutati mediante pancreas artificiale.