Influence of Vaccinum cholericum, Polyvaccinum and Alavac S preparation on mu-IFN-alpha production.
Investigations were carried out on the effect of Vaccinum cholericum, Polyvaccinum and Alavac S preparations on interferon synthesis in mouse. These preparations, injected i.v. or i.p. prior to viral inducer, were shown to inhibit IFN production. The inhibition was observed also when interferon was induced in vitro in peritoneal cells of mice pretreated with these preparations.
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology; D001249:Asthma / Q000276:immunology / Q000628:therapy; D001428:Bacterial Vaccines / Q000276:immunology*; D022121:Cholera Vaccines / Q000276:immunology; D006801:Humans; D007167:Immunotherapy; D066298:In Vitro Techniques; D007370:Interferon Type I / Q000096:biosynthesis*; D051379:Mice; D008815:Mice, Inbred Strains
D001428:Bacterial Vaccines; D022121:Cholera Vaccines; D007370:Interferon Type I