Detection of the rare PGM1(3) allele. Further biochemical and genetic characterization of the PGM1(3) isozymes.
A family possessing the rare PGM1(3) allele has been found in North Carolina, and criteria for the electrophoretic separation and accurate typing of the PGM1(3) isozymes are outlined. The PGM1(3) isozymes detected proved to be useful in helping to determine parentage in an incest investigation. The pattern of segregation of the PGM1(3) allele in four generations of this family and thermostability studies on the PGM1(3) isozymes are presented.
D000483:Alleles; D004592:Electrophoresis, Starch Gel; D005260:Female; D006801:Humans; D007179:Incest; D007527:Isoenzymes / Q000235:genetics*; D008297:Male; D010334:Paternity; D010375:Pedigree; D010641:Phenotype; D010733:Phosphoglucomutase / Q000235:genetics*
D007527:Isoenzymes; D010733:Phosphoglucomutase