Studies on the degradation of fibrinogen by proteolytic enzymes from the larvae of Lanomia achelous (Cramer).
Fibrinogen degradation products formed by the action of purified haemolymph and saliva of a Saturnidae caterpillar of the Lonomia genus were studies by immunoelectrophoresis and polyacrylamide/SDS gel electrophoresis. The pattern of degradation differ form the one described for plasmin, trypsin, brinase, and ochrase. The most striking difference being the rapid loss of the alpha chain in spite of the presence of the protease inhibitor aprotinin, and/or denaturalizing agents such as 8 M Urea and 2% SDS.
D000818:Animals; D001954:Brinolase / Q000032:analysis; D002080:Butterflies / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D005340:Fibrinogen / Q000032:analysis; D005341:Fibrinolysin / Q000032:analysis; D006458:Hemolymph / Q000032:analysis; D006801:Humans; D007122:Immunoelectrophoresis; D007814:Larva; D007915:Lepidoptera / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism*; D012463:Saliva / Q000032:analysis; D014357:Trypsin / Q000032:analysis
D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen; D010447:Peptide Hydrolases; D014357:Trypsin; D005341:Fibrinolysin; D001954:Brinolase