Early post-operative changes in left ventricular dimensions and mass following valve replacement in adults with aortic stenosis.
Twelve adults with isolated valvular aortic stenosis (AS) were evaluated for early changes of left ventricular (LV) dimensions and mass (LVM/M2) following valve replacement (AVR). M-mode echocardiography was performed pre- and 3 to 5 weeks post-AVR. LV internal diameter (LVID) decreased from 51 +/- 2.0 to 46 +/- 2.7 mm post-AVR (p less than .02). Reduction of posterior wall thickness (PWT) from 12 +/- 0.7 to 10 +/- 0.6 mm (p less than .01), interventricular septal thickness (IVST) from 13 +/- 0.9 to 11 +/- 1.2 mm (p less than .005), and mean myocardial thickness (MMT) from 12.4 +/- 0.7 to 10.5 +/- 0.7 (p less than .001), occurred post-AVR. Wall thickness/internal radius ratio was unchanged post-AVR. Calculated LVM/M2 decreased from 170 +/- 15 to 110 +/- 13 grams post-AVR (p less than .001). Normalized posterior wall velocity (PWVn) increased post-AVR from 0.66 +/- .05 to 1.08 +/- .10 sec-1 (p less than .001). For all twenty four studies, LVM/M2 and PWVn were correlated (r = -0.725, p less than .001). In summary, LV dimensions and LVM/M2 decreased significantly 3 to 5 weeks post-AVR in adults with AS. There was significant correlation of LVM/M2 and PWVn for pre-AVR and post AVR studies.
D000328:Adult; D000368:Aged; D001024:Aortic Valve Stenosis / Q000601:surgery*; D006332:Cardiomegaly / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D006352:Heart Ventricles / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size