Maprotiline hydrochloride associated with a clinical state of catatonic stupor and epileptic encephalogram.
The authors describe a patient with major affective disorder, unipolar depressed type, recurrent, psychosis who went into a catatonic stupor state while being treated with maprotiline hydrochloride and thiothixene. The article also deals with findings on electroencephalogram, response to treatment, a review of other similar case reports, and the clinical significance and relevance based upon which other clinicians can take some precautionary measures while prescribing this newer antidepressant, especially in combination with a neuroleptic.
D000873:Anthracenes / Q000009:adverse effects*; D002389:Catatonia / Q000139:chemically induced*; D003866:Depressive Disorder / Q000188:drug therapy; D003975:Diazepam / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004827:Epilepsy / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008376:Maprotiline / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D010672:Phenytoin / Q000627:therapeutic use; D013888:Thiothixene / Q000627:therapeutic use
D000873:Anthracenes; D008376:Maprotiline; D010672:Phenytoin; D013888:Thiothixene; D003975:Diazepam