[Angiographic examinations of the circulatory development of living chick embryos (author's transl)].
In chick embryos of an age of incubation of 5-14 days, the physiological development of the circulation and the morphological differentiation of the arterial system were studied by intravital and postmortal angiography. For the examinations of the living embryos, a special radiographic and injection technique had to be developed. The contrast medium was injected into the umbilical veins and transported by the actions of the embryonic heart. Continuous ECG recordings showed no marked interference of the injections with the cardiac activity. According to the angiographic findings, the circulation is relatively fast within the main arteries, but the capillary perfusion is prolonged and lasts up to several minutes. The average circulatory velocity of the blood stream within the carotid artery increases parallel to the arterial enlargement, whereas the circulatory time decreases and the number of heart beats during the period of carotid opacification does not change to a great extent. By this, a steady transport of gas and nutritional material may be achieved in the growing arterial system.
D000792:Angiography; D000818:Animals; D001775:Blood Circulation; D001783:Blood Flow Velocity; D002319:Cardiovascular System / Q000196:embryology*; D002339:Carotid Arteries / Q000196:embryology; D002642:Chick Embryo / Q000254:growth & development*; D003287:Contrast Media; D008722:Methods
D003287:Contrast Media
Angiographische Untersuchungen der Kreislaufentwicklung bei lebenden Hühnerembryonen.