Trials with a long acting parenteral selenium preparation in ruminants: sheep.
Barium selenate was developed as a long-acting subcutaneous injection for selenium treatment. The results from trials using this product show that it is a safe preparation for treating and preventing selenium deficiency in sheep. It produces a satisfactory selenium status which will be maintained for at least six months and, when injected into pregnant ewes, results in the transfer of selenium from the ewe to its progeny.
D000818:Animals; D001464:Barium / Q000008:administration & dosage / Q000627:therapeutic use*; D017609:Barium Compounds; D003300:Copper / Q000008:administration & dosage; D003692:Delayed-Action Preparations; D004341:Drug Evaluation / Q000662:veterinary; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D007279:Injections, Subcutaneous / Q000662:veterinary; D008715:Methionine / Q000008:administration & dosage / Q000031:analogs & derivatives; D009942:Organometallic Compounds; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000662:veterinary; D064586:Selenic Acid; D012643:Selenium / Q000008:administration & dosage / Q000172:deficiency* / Q000627:therapeutic use*; D018036:Selenium Compounds; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*
D017609:Barium Compounds; D003692:Delayed-Action Preparations; D009942:Organometallic Compounds; D018036:Selenium Compounds; C042079:copper methionate; D001464:Barium; D003300:Copper; D008715:Methionine; D005979:Glutathione Peroxidase; D012643:Selenium; D064586:Selenic Acid; C042078:barium selenate