Alkyl-substituted gamma-butyrolactones inhibit [35S]TBPS binding to a GABA linked chloride ionophore.
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000494:pharmacology*; D000818:Animals; D001463:Barbiturates / Q000494:pharmacology; D001921:Brain / Q000378:metabolism; D001643:Bridged Bicyclo Compounds / Q000378:metabolism*; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism*; D005663:Furans / Q000494:pharmacology*; D066298:In Vitro Techniques; D007476:Ionophores / Q000378:metabolism*; D008297:Male; D008566:Membranes / Q000378:metabolism; D010852:Picrotoxin / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D015107:4-Butyrolactone; D001463:Barbiturates; D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds; D002712:Chlorides; D005663:Furans; D007476:Ionophores; D010852:Picrotoxin; D005680:gamma-Aminobutyric Acid; C037476:tert-butylbicyclophosphorothionate