title: [Diagnostic and therapeutic approach in thromboembolism disease. Reflexions apropos of 105 cases].
abstract: 105 patients suffering from thrombo-embolic disease (MTE) were explored by venography of the lower limbs, ilio-vena cavography and pulmonary angiography at the time of the initial diagnostic work up. These examinations served as a control for the different therapies, anticoagulants, thrombolytics, curative and preventive surgery, separately (77 controls) or in association (92 controls). From the base-line vascular investigations it appears that the gravity of the pulmonary emboli was not correlated with either a proximal or distal site of venous thrombosis. From the results of controlled therapy there were significant differences between the efficacy of medical treatment at the level of the pulmonary artery and at venous level where the progression of phlebo-thrombosis was often seen. Recurrence of emboli and overall prognosis of the disease usually depended on the persistence of thrombi at venous level. Such a phlebo-thrombosis is rarely aggravated by techniques of partial interruption of the inferior vena cava (IPVCI) which ensure effective protection of the pulmonary circulation. The IPVCI often appears to be the only effective method of preventing recurrent pulmonary emboli, which has led us to reconsider its indications.
mesh_terms: D000792:Angiography; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000628:therapy*; D013923:Thromboembolism / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D013924:Thrombophlebitis / Q000000981:diagnostic imaging / Q000628:therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
chemical_list: D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Attitude diagnostique et thérapeutique au cours de la maladie thrombo-embolique. Réflexions à propos de 105 malades.