title: Oral urea in the treatment of colo-rectal liver metastases.
abstract: A consecutive series of 10 patients with hepatic metastases from colo-rectal carcinoma have been treated with oral urea. This substance has been reported to produce regression of hepatic secondaries from a variety of primary sources including colon. Although well tolerated, and leading to subjective improvement in some patients, no objective benefit has been confirmed from the treatment in this study.
mesh_terms: D000284:Administration, Oral; D003110:Colonic Neoplasms / Q000188:drug therapy*; D004341:Drug Evaluation; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D012004:Rectal Neoplasms / Q000188:drug therapy*; D014508:Urea / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014508:Urea