title: Occlusive arterial disease in young patients.
abstract: All the young patients (under 40 years) affected by occlusive arterial disease observed at the Istituto di Clinica Chirurgica II, University of Milan, during the last eleven years have been reviewed. About one third of these patients is affected by a form of arteritis; the others demonstrate the typical pattern of early atherosclerosis or an indeterminate condition which may represent an atherosclerotic complication superimposed on a basic arteritic lesion. The available therapeutic procedures are examined. They show that atherosclerotic disease more frequently permits a surgical reconstruction. The average rate of amputation is about the same in the two considered forms, ranging close to 7-8%. The 10 year follow up of these groups of young patients allowed us to analyze the rate of progression and evolution of these morbid conditions and the influence of the most important risk factors.
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D001161:Arteriosclerosis / Q000145:classification / Q000628:therapy; D048909:Diabetes Complications; D004691:Endarterectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D008055:Lipids / Q000097:blood; D008297:Male; D012306:Risk; D012907:Smoking; D013562:Sympathectomy; D013919:Thromboangiitis Obliterans / Q000145:classification / Q000628:therapy
chemical_list: D008055:Lipids