[Early treatment of congenital hypoplasia of the penis with intramuscular delayed-action testosterone].
Three intramuscular injections of 25 to 50 mg of testosterone hexahydrobenzoate were prescribed in 37 boys who presented with hypoplastic penis: 16 with micropenis and normally placed urethra, 21 with hypospadias. Ages ranged from 4 months to 9 years. In almost all children treated between the ages of 6 and 18 months, penis growth became normal for age. Growth and bone maturation were temporarily accelerated but in a parallel fashion, so that this very early androgen-therapy need not reduce the adult height of children thus treated.
D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003692:Delayed-Action Preparations; D005500:Follow-Up Studies; D006128:Growth / Q000187:drug effects; D006801:Humans; D007021:Hypospadias / Q000188:drug therapy*; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D010413:Penis / Q000002:abnormalities*; D013739:Testosterone / Q000008:administration & dosage / Q000627:therapeutic use*
D003692:Delayed-Action Preparations; D013739:Testosterone
Le traitement précoce des hypoplasies congénitales de la verge par la testostérone-retard intramusculaire.