The effect of naloxone on schedule-induced and other drinking.
A dose-response study of the effect of naloxone on schedule-induced drinking confirmed that this type of drinking is resistant to the opiate antagonist at doses which depressed drinking induced by water-deprivation, hypertonic saline and salbutamol. Naloxone also failed to reduce intake of saline solution in the presence of scheduled food presentation. The findings support the suggestion that schedule-induced drinking is regulated by a system of neural control which differs from that involved in deprivation and other forms of drinking. It would appear that opiate receptors do not play a part in the regulation of schedule-induced drinking.
D000420:Albuterol / Q000494:pharmacology; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004327:Drinking Behavior / Q000187:drug effects* / Q000502:physiology; D004334:Drug Administration Schedule; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012462:Saline Solution, Hypertonic / Q000494:pharmacology; D014868:Water Deprivation / Q000502:physiology
D012462:Saline Solution, Hypertonic; D009270:Naloxone; D000420:Albuterol