Histoplasma capsulatum in the eye.
The ocular pathologic findings in an immunosuppressed patient who died of disseminated histoplasmosis are described. Histoplasma capsulatum was found in large numbers within the endothelial cells of the choroid, in one area each of the ciliary body and trabecular meshwork. There was a minimal inflammatory response. No granulomas were noted. Previously reported cases of ocular histoplasmosis in immunosuppressed patients are similar in that, with one exception, granulomatous inflammation was not demonstrated. Thirteen eyes in which histoplasma organisms have been found in the eye are reviewed.
D000328:Adult; D002675:Child, Preschool; D002829:Choroid / Q000473:pathology*; D002924:Ciliary Body / Q000473:pathology*; D005260:Female; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D014129:Trabecular Meshwork / Q000473:pathology; D014603:Uveal Diseases / Q000209:etiology* / Q000473:pathology
D007166:Immunosuppressive Agents