Color as a risk factor in iris melanoma.
We reviewed 23 iris melanomas for iris color and gross tumor pigmentation. Patients with iris melanoma had lighter irides than both population controls (x2 = 58.0; P less than .0001) and other patients with uveal melanoma (x2 = 17.1; P = .002). Amelanotic and lightly melanotic tumors occurred predominantly in the patients with light irides.
D005127:Eye Color; D006801:Humans; D007499:Iris Diseases / Q000209:etiology*; D008545:Melanoma / Q000209:etiology*; D012306:Risk; D014604:Uveal Neoplasms / Q000209:etiology*