[Quantitative histoenzymological characteristics of changes in the red and white fibers of skeletal muscle tissue of the extremities in temporary ischemia and postischemic recirculation].
Histoenzymological study of red and white fibers of limb skeletal muscles was performed in dogs with experimental acute occlusion of aorta trifurcation during ischemic and postischemic periods. A dramatic fall in the activity of aerobic enzymes was recorded in all observation periods (3, 6, 9 and 12 h). LDH activity rose considerably during short-term and descended slowly in prolonged ischemia. Red muscle fibers showed more substantial disorders in metabolism than white fibers. Recirculation after 6, 9 and 12 h of ischemia led to an appreciable decrease in the metabolic rate in muscle tissue. Irreversibility of metabolic alterations in acute ischemia lasting over 6 h may attest to the failure of the compensatory-adaptive mechanisms.
D000208:Acute Disease; D000332:Aerobiosis; D000693:Anaerobiosis; D000818:Animals; D002952:Citric Acid Cycle; D004285:Dogs; D005121:Extremities / Q000098:blood supply; D005260:Female; D006019:Glycolysis; D006651:Histocytochemistry; D007511:Ischemia / Q000201:enzymology*; D008297:Male; D009132:Muscles / Q000098:blood supply / Q000201:enzymology*; D012039:Regional Blood Flow; D013997:Time Factors
Kolichestvennaia gistoénzimologicheskaia kharakteristika izmeneniĭ krasnykh i belykh volokon skeletnoĭ myshechnoĭ tkani konechnosteĭ pri vremennoĭ ishemii i postishemicheskoĭ retsirkuliatsii.