Effects of vascular occlusion on the femoral head in growing rabbits.
Temporary vascular occlusion of the femoral head in 6-week-old rabbits was produced by a closed means in a hip spica; the hips were maintained for 24 h in the position of flexion, abduction and internal rotation. All animals developed necrosis of the capital femoral epiphysis, best seen histologically at 2 weeks, and this subsequently recovered. Despite marked histological changes only one hip developed radiographic changes.
D000818:Animals; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000473:pathology; D004195:Disease Models, Animal; D005270:Femur Head / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000473:pathology*; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000502:physiology; D007103:Immobilization; D007511:Ischemia / Q000000981:diagnostic imaging / Q000473:pathology; D011817:Rabbits; D011859:Radiography