title: [Regression of a massive hydronephrosis in familial central diabetes insipidus treated with Adiuretin].
abstract: A ten year old boy with hereditary pituitary diabetes insipidus presented with massive bilateral hydronephrosis, hydroureters and an extremely large bladder. Radiological investigations excluded a mechanical obstruction or vesicoureteral reflux. Treatment with the adiuretin analog DDAVP resulted in regression of the urinary tract changes after 5 months and an almost complete disappearance after 3 1/2 years. The urinary tract dilatation probably results from the large urine flows which exceed the capacity of the urinary tract causing a functional obstruction and residual urine.
mesh_terms: D001127:Arginine Vasopressin / Q000627:therapeutic use*; D002648:Child; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D003919:Diabetes Insipidus / Q000188:drug therapy* / Q000235:genetics; D006801:Humans; D006869:Hydronephrosis / Q000188:drug therapy*; D008297:Male
chemical_list: D001127:Arginine Vasopressin; D003894:Deamino Arginine Vasopressin
vernacular_title: Rückbildung einer massiven Hydronephrose bei familiärem zentralen Diabetes insipidus unter Adiuretin-Therapie.