title: Thrombolytic therapy for superior vena caval thrombosis following superior vena cava-pulmonary artery anastomosis.
abstract: Immediate postoperative thrombosis of left superior vena cava-left pulmonary artery anastomosis in a modified Fontan procedure for single ventricle and pulmonary artery stenosis is described. Before thrombolytic therapy with streptokinase is initiated, confirmation of thrombosis by venography is mandatory to lessen the risk of cardiac tamponade or hemothorax. By this technique major surgical intervention is avoided, but close attention to the dose of streptokinase and the coagulation profile is essential. Measures to be taken if bleeding occurs with streptokinase therapy are described.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D006352:Heart Ventricles / Q000002:abnormalities; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy / Q000503:physiopathology; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D011666:Pulmonary Valve Stenosis / Q000150:complications / Q000601:surgery; D011859:Radiography; D013300:Streptokinase / Q000627:therapeutic use*; D013927:Thrombosis / Q000188:drug therapy* / Q000503:physiopathology; D014683:Vena Cava, Superior / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D013300:Streptokinase