Dermal Merkel cells in the nevus of Ota and leopard syndrome.
We observed dermal Merkel cells around vellus hair follicles in one patient with nevus of Ota and one with leopard syndrome. These Merkel cells were in contact with Schwann cells and nerve endings in the dermis. The question of whether or not Merkel cells exist normally in adult dermis remains unanswered. However, their presence in these abnormal conditions suggests that normally they do occur in the dermis but go undetected because their numbers are so few or they are in a form not readily identifiable by currently available methods.
D000015:Abnormalities, Multiple / Q000473:pathology; D000328:Adult; D000368:Aged; D005153:Facial Neoplasms / Q000648:ultrastructure*; D005260:Female; D006330:Heart Defects, Congenital / Q000473:pathology; D006801:Humans; D007911:Lentigo / Q000473:pathology*; D008297:Male; D009508:Nevus, Pigmented / Q000648:ultrastructure*; D012867:Skin / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000648:ultrastructure*; D013577:Syndrome