[The pituitary-adrenal system in cancer of the esophagus and stomach].
Excretion of corticosteroids, levels of 11-OCS in blood plasma, tests with dexasone and clinical evaluation of the pituitary-adrenal system function were studied in 354 patients with carcinomas of the esophagus and proximal stomach division. Some degree of hypocorticism with a decrease in the 11-OCS level in blood plasma and lowered excretion of corticosteroids in the urine were found in 71% of patients. These variations are accompanied by lowered hypothalamus sensitivity to dexasone. Similar disturbances though less pronounced are determined in the precancerous states and in the remote periods after operation.
D015065:17-Hydroxycorticosteroids / Q000097:blood / Q000652:urine; D015068:17-Ketosteroids / Q000097:blood / Q000652:urine; D000328:Adult; D000368:Aged; D003907:Dexamethasone; D004938:Esophageal Neoplasms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010912:Pituitary-Adrenal Function Tests; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D013274:Stomach Neoplasms / Q000503:physiopathology*
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D003907:Dexamethasone
Gipofizatno-nadpochechnikovaia sistema pri rake pishchevoda i heludka.