Plasmid content and pathogenicity of Campylobacter jejuni and Campylobacter coli strains in the pregnant guinea pig model.
Strains of Campylobacter jejuni and C coli from human and animal sources were assessed for pathogenicity by their capability to produce abortions in pregnant guinea pigs. The pathogenicity rate varied from 7% to 87% for the C jejuni strains and from 0% to 53% for the C coli strains. Plasmid carriage was not found to correlate with pathogenicity as determined by ability of the strains to produce abortions in the pregnant guinea pig model.
D000034:Abortion, Veterinary / Q000453:epidemiology*; D000818:Animals; D002167:Campylobacter / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*; D002168:Campylobacter fetus / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*; D004269:DNA, Bacterial / Q000032:analysis; D004270:DNA, Circular / Q000032:analysis; D004195:Disease Models, Animal; D004352:Drug Resistance, Microbial; D005260:Female; D006168:Guinea Pigs; D008970:Molecular Weight; D010957:Plasmids; D011247:Pregnancy; D013752:Tetracycline / Q000494:pharmacology
D004269:DNA, Bacterial; D004270:DNA, Circular; D013752:Tetracycline