Lumbar myelography with iohexol and metrizamide. A double-blind clinical trial.
Two non-ionic contrast media, iohexol and metrizamide, were compared in a double-blind clinical trial which included 50 patients who underwent lumbar myelography for disc herniation or spinal stenosis. The frequency of adverse reactions was lower for iohexol which is recommended for extended trials and for examination of other compartments of the subarachnoid space.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000009:adverse effects; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006261:Headache / Q000139:chemically induced; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging; D007463:Iodobenzoates; D007472:Iohexol; D007866:Leg; D008161:Lumbosacral Region; D008297:Male; D008793:Metrizamide / Q000009:adverse effects; D008875:Middle Aged; D009192:Myelography / Q000379:methods*; D009325:Nausea / Q000139:chemically induced; D009460:Neurologic Examination; D010146:Pain / Q000139:chemically induced; D013130:Spinal Stenosis / Q000000981:diagnostic imaging; D013346:Subarachnoid Space / Q000000981:diagnostic imaging; D014283:Triiodobenzoic Acids / Q000009:adverse effects
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008793:Metrizamide