[Phospholipid composition of tumors and homologous tissues of rats exposed to dimethylnitrosamine].
Quantitative changes in phospholipid spectra of blood serum, liver, kidneys and tumour tissues were determined at different stages of carcinogenesis induced by nitrosodimethylamine in rats. It was established that tissue of kidney tumours differs from homologous tissue only in the total amount of phospholipids as well as of cardiolipin phosphatidylethanolamine, phosphatidylserine and sphingomyelin. Essential changes were revealed in the phospholipid spectrum of blood serum and liver of tumour-bearing rats. The inverse correlation was found in phosphatidylethanolamine and phosphatidylserine amount in these tissues.
D000818:Animals; D004128:Dimethylnitrosamine; D007668:Kidney / Q000378:metabolism; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008113:Liver Neoplasms / Q000139:chemically induced / Q000378:metabolism*; D008297:Male; D010743:Phospholipids / Q000097:blood / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D010743:Phospholipids; D004128:Dimethylnitrosamine
Fosfolipidnyĭ sostav opukholeĭ i gomologichnykh tkaneĭ krys pri vozdeĭstvii nitrozodimetilamina.