title: Respiratory behavior in groups of deaf and non-deaf GFF male mice.
abstract: Carbon dioxide emission (VCO2) of groups of 10 GFF mice, genetically deaf and non-deaf, were compared, in controlled conditions of temperature 20-21 degrees C, humidity 50-80% and light (LD12:12; L = 108 lux). A circadian rhythm of VCO2 was evidenced in both genotypes, with levels in D and in L significantly (0.001 less than p less than 0.01) greater in deaf than in non-deaf mice. Photic VCO2 variations were significantly (0.001 less than p less than 0.05) smaller at L----D and D----L in the deaf than in non-deaf genotype. Ultradian (tau greater than 20 minutes) rhythms were evidenced in both genotypes; Fourier periodic analysis showed several significant (0.001 less than p less than 0.05) differences between these 2 genotypes concerning mainly amplitudes, whilst spectral analysis showed slight frequency differences between them. Survival to an acute nitrogen hypoxia or to an acute carbon monoxide intoxication which was significantly (p less than 0.001 and p less than 0.05) lower in deaf than in non-deaf individuals confirms the differences in respiratory behavior of groups of these two strains of mice.
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D001831:Body Temperature; D002249:Carbon Monoxide Poisoning / Q000150:complications; D003638:Deafness / Q000150:complications / Q000235:genetics / Q000503:physiopathology*; D004562:Electrocardiography; D006128:Growth; D000860:Hypoxia / Q000150:complications; D008027:Light; D008297:Male; D051379:Mice; D009043:Motor Activity; D012119:Respiration