[Comparison of 2 chemosensitivity tests by grafting a polyoma tumor in the cheek pouch of syngeneic hamsters and under the renal capsule of syngeneic mice].
The immunocompetent subrenal capsule assay tumour graft is a good chemosensitivity test. We have compared it to immunocompetent white hamster cheek pouch tumour graft. These two assays are both easy to perform. Each has specific advantages and disadvantages. However the six days immunocompetent mouse subrenal capsule assay tumour graft is the most practicable and reproducible. The hamster cheek pouch assay would be used when mouse subrenal capsule assay would not be efficient for the molecules under study.
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002610:Cheek / Q000601:surgery; D006224:Cricetinae; D005354:Fibrosarcoma / Q000188:drug therapy*; D007672:Kidney Cortex / Q000601:surgery; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000188:drug therapy*
D000970:Antineoplastic Agents
Comparaison de deux tests de chimiosensibilité par greffe d'une tumeur polyome dans la poche jugale du hamster syngénique et sous la capsule rénale de la souris syngénique.