[Analysis of the plastic properties of the postsynaptic neuron in the sensory motor cortex in response to repeated microphoretic administration of gamma-aminobutyric acid].
The absence of habituation effect to the iontophoretic repetitive applications with 120, 30 and 15 seconds intervals of inhibition transmitter--gamma aminobutiric acid (GABA)--in sensomotor cortex neurons has been established. Earlier habituation effect has been discovered under the same experimental conditions during other transmitter administration--acetilcholine. A hypothesis concerning the absence of biological expendiency of habituation in the GABA-ergic system is suggested.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D004548:Elasticity; D005260:Female; D007478:Iontophoresis; D009044:Motor Cortex / Q000187:drug effects*; D009433:Neural Inhibition / Q000187:drug effects; D009474:Neurons / Q000187:drug effects*; D051381:Rats; D013003:Somatosensory Cortex / Q000187:drug effects*; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid
Analiz plasticheskikh svoĭstv postsinapticheskogo neĭrona sensomotornoĭ oblasti kory pri povtoriaiushcheĭsia mikroforeticheskoĭ applikatsii gamma-aminomaslianoĭ kisloty.