Lack of cross-reactivity between human placental and rat liver glucocerebrosidases.
The production of anti-human placental glucocerebrosidase antibodies in rabbits immunized with a mixture of human placental glucocerebrosidase and Freund's complete adjuvant was confirmed by the immunoprecipitation reaction, immunocompetition and Graber and Williams' immunoelectrophoresis. These immunochemical techniques also unviled a lack of cross-reactivity between human placental and rat liver glucocerebrosidases against the rabbit antiserum.
D000818:Animals; D001667:Binding, Competitive; D003429:Cross Reactions; D005959:Glucosidases / Q000276:immunology*; D005962:Glucosylceramidase / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis; D008099:Liver / Q000201:enzymology*; D010920:Placenta / Q000201:enzymology*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity
D005959:Glucosidases; D005962:Glucosylceramidase