Different aggregation properties of sea urchin embryonic cells at different developmental stages. II. Stage specific response to fibronectin and collagen.
Fibronectin and collagen were added to cells dissociated from embryos at the blastula and at the 16 cell stages. Both molecules stimulate aggregation of cells dissociated from blastula but they do not affect aggregation of blastomeres dissociated from the 16 cell stage. The stage-specific response to fibronectin and collagen appears to be related to the onset of new functional role(s) of the two molecules at the blastula stage.
D000818:Animals; D001755:Blastocyst / Q000187:drug effects / Q000502:physiology; D015815:Cell Adhesion Molecules; D002449:Cell Aggregation / Q000187:drug effects*; D003094:Collagen / Q000494:pharmacology*; D005353:Fibronectins / Q000494:pharmacology*; D011506:Proteins / Q000494:pharmacology; D012617:Sea Urchins / Q000187:drug effects / Q000196:embryology*; D013045:Species Specificity
D015815:Cell Adhesion Molecules; D005353:Fibronectins; D011506:Proteins; C013065:cell aggregation factors; D003094:Collagen