Quantitative determination of angiotensin II binding sites in rat brain and pituitary gland by autoradiography.
Rat brain and pituitary angiotensin II (AII) binding sites were quantitated by incubation of tissue sections with 125I-[Sar1] AII, Ultrofilm radioautography, computerized densitometry, and comparison with 125I-standards at appropriate film exposure times. The highest number of AII binding sites was found in anterior pituitary and the circumventricular organs, organon subfornicalis and organon vasculosum laminae terminalis.
D000804:Angiotensin II / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D001665:Binding Sites; D001921:Brain / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000378:metabolism; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism; D010902:Pituitary Gland / Q000378:metabolism*; D051381:Rats; D012686:Septal Nuclei / Q000378:metabolism; D013356:Subfornical Organ / Q000378:metabolism; D013493:Suprachiasmatic Nucleus / Q000378:metabolism
D000804:Angiotensin II