Treatment of osteoporosis with sodium fluoride and calcium: effects on vertebral fracture incidence and bone histomorphometry.
This article contains a report of the results of a study of 10 postmenopausal women with uncomplicated osteoporosis who were treated with sodium fluoride, calcium supplementation, and vitamin D. Spinal fractures ceased by 18 months, trabecular bone mass increased 26 per cent per year, and patients reported symptomatic improvement.
D000368:Aged; D001706:Biopsy; D002118:Calcium / Q000627:therapeutic use*; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D007085:Ilium / Q000473:pathology; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012969:Sodium Fluoride / Q000627:therapeutic use*; D013904:Thoracic Vertebrae / Q000293:injuries*; D013997:Time Factors; D014807:Vitamin D / Q000627:therapeutic use
D014807:Vitamin D; D012969:Sodium Fluoride; D002118:Calcium