Fasciculation of the eyelids: an additional clue to clinical diagnosis in spinal muscular atrophy.
Fasciculation of the eyelids was observed in five of eleven children with spinal muscular atrophy (SMA); two had severe SMA and three were of intermediate severity. Three other children with intermediate SMA and the two children with mild SMA did not show eyelid fasciculations. This could provide an additional clinical sign to tongue fasciculation and hand tremor in the diagnosis of SMA in childhood.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005143:Eyelids / Q000503:physiopathology*; D005207:Fasciculation / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009133:Muscular Atrophy / Q000175:diagnosis* / Q000503:physiopathology; D009461:Neurologic Manifestations / Q000175:diagnosis*; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000503:physiopathology