Postmenopausal ovarian follicle cyst: an unusual cause of estrogen excess.
Six years after menopause, a 61-year-old woman complained of enlarging, tender breasts. The serum follicle-stimulating hormone level was 62 mIU/ml; the serum estradiol value was 91 pg/ml; and challenge with progesterone, 100 mg i.m., induced withdrawal bleeding. Histologic examination of a hysterectomy with bilateral salpingo-oophorectomy specimen showed proliferative endometrium and an involuting, luteinized follicle cyst of the left ovary. A follicle cyst causing symptomatic hyperestrogenism after a menopause documented by biochemical tests has not been previously reported.
D004967:Estrogens / Q000378:metabolism*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010048:Ovarian Cysts / Q000175:diagnosis / Q000503:physiopathology*; D006080:Ovarian Follicle / Q000378:metabolism
D004967:Estrogens