title: [Computer tomographic studies in Wilson disease].
abstract: 5 patients with proven Wilson's disease had clinical examinations and follow-up scans up to 6 years while being under penicillamine treatment. Severe neurological deficits were associated with marked CT abnormalities. In all other cases clinical condition and CT finding was only loosely correlated. Under therapy, some hypodense areas normalized their attenuation partially or completely. In primarily normal CT's, cupruresis did not induce alterations. As there is no firm correlation between CT findings and clinical involvement the CT examination is of limited value in prognosis.
mesh_terms: D000293:Adolescent; D000328:Adult; D001928:Brain Diseases, Metabolic / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006527:Hepatolenticular Degeneration / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D008297:Male; D010396:Penicillamine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D010396:Penicillamine
vernacular_title: Computertomographische Verlaufsuntersuchungen bei Morbus Wilson.