title: [Carcinoma of the hypophysis with acromegaly].
abstract: A 38-year old man deceased after being operated on recurring pituitary adenoma removed 13 years ago. Autopsy showed a massive spread of tumour on dura and in subarachnoid space. Growth hormone producing cells were found prevailing in the primary tumour as well as in secondaries by immunohistochemistry and immunofluorescence which concurred with acromegaly. Many cells produced prolactin. The tumour spreading discontinually in subdural and subarachnoid space was taken for a carcinoma.
mesh_terms: D000172:Acromegaly / Q000209:etiology*; D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology
chemical_list: D013006:Growth Hormone
vernacular_title: Karcinom hypofýzy s akromegalií.