Chemotaxis in experimental syphilis.
Peritoneal exudate leukocytes from normal and Treponema pallidum-infected rabbits were examined for their chemotactic response to various chemoattractants and treponemal preparations. Leukocytes from normal and infected animals responded well to bacterial and serum-derived chemoattractants. Suspensions of washed Treponema phagedenis biotype Reiter but not T. pallidum exerted significant chemotactic activity. Cells from rabbits infected for greater than or equal to 7 days demonstrated increased locomotion, suggesting the possibility of increased random motility.
D000818:Animals; D002634:Chemotaxis, Leukocyte; D007700:Kinetics; D010537:Peritoneum / Q000166:cytology; D011817:Rabbits; D013587:Syphilis / Q000276:immunology*; D014208:Treponema / Q000276:immunology