[Role of polypeptide factors of the hypothalamus and epiphysis in regulating the function of stem cell precursors of granulomonopoiesis].
The claster- and colony-formation capacity of the offls--precursors of granulomonopoiesis in 29 normal subjects was studied in a bilayer agar system. Parallel cultures were used to investigate the effects of polypeptide factors of the hypothalamus and epiphysis. It was found that polypeptide factors of the hypothalamus and epiphysis have a regulatory influence on granulomonopoiesis at the level of precursor cells.
D000818:Animals; D002417:Cattle; D003114:Colony-Forming Units Assay; D006098:Granulocytes / Q000187:drug effects*; D006410:Hematopoiesis / Q000187:drug effects*; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D006801:Humans; D007031:Hypothalamus; D009000:Monocytes / Q000187:drug effects*; D010455:Peptides / Q000494:pharmacology*; D010870:Pineal Gland
D010455:Peptides
Rol' polipeptidnykh faktorov gipotalamusa i épifiza v reguliatsii funktsional'noĭ aktivnosti stvolovykh kletok-predshestvennikov granulomonopoéza.