Quantitation of metronidazole in pharmaceutical dosage forms using high-performance liquid chromatography.
A high-performance liquid chromatographic (HPLC) method for the quantitation of metronidazole in pharmaceutical dosage forms has been developed. The method is accurate and precise with an RSD of 0.68%, based on six readings. The excipients present in various dosage forms did not interfere with the assay procedure. A solution of metronidazole decomposed using heat showed 0% potency.
D002851:Chromatography, High Pressure Liquid; D008795:Metronidazole / Q000032:analysis*; D011208:Powders; D012996:Solutions; D013607:Tablets
D011208:Powders; D012996:Solutions; D013607:Tablets; D008795:Metronidazole