The reversal of epidural morphine induced somnolence with physostigmine.
Two case reports are presented of patients with post-thoracotomy pain treated with epidural morphine who developed somnolence several hours after the procedure. Physostigmine, 1 mg IV successfully reversed the somnolence without any effect on analgesia.
D000368:Aged; D000767:Anesthesia, Epidural; D006801:Humans; D008168:Lung / Q000601:surgery; D008297:Male; D009020:Morphine / Q000009:adverse effects* / Q000627:therapeutic use; D010149:Postoperative Pain / Q000188:drug therapy*; D010830:Physostigmine / Q000627:therapeutic use*; D012890:Sleep / Q000187:drug effects*
D009020:Morphine; D010830:Physostigmine