title: Treatment of typhoid fever with cefamandole.
abstract: Cefamandole therapy was evaluated in nine patients with typhoid fever. Six patients, including all five who received the antibiotic by continuous intravenous drip (8.0 g daily), were cured. Dosage schedules resulting in maintenance of antibiotic concentrations in serum high above the MIC seemed to correlate well with treatment success.
mesh_terms: D000293:Adolescent; D000328:Adult; D002435:Cefamandole / Q000097:blood / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D014435:Typhoid Fever / Q000188:drug therapy*
chemical_list: D002435:Cefamandole