title: Hemangioendothelioma with intravascular coagulation and ischemic colitis.
abstract: An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and involved the inferior mesenteric artery, resulting in ischemic colitis of the left colon. A discussion regarding the pathophysiology with respect to endothelial cell properties and other microscopic features of the tumor is presented.
mesh_terms: D000005:Abdomen / Q000098:blood supply; D003092:Colitis / Q000209:etiology*; D003106:Colon / Q000098:blood supply; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D006390:Hemangioendothelioma / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000150:complications; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000150:complications*; D013848:Thigh / Q000098:blood supply