Serum-virus simultaneous method of immunisation against peste des petits ruminants.
Peste des petits ruminants (PPR) hyperimmune serum was prepared in cattle and used to protect goats against PPR. The serum was well tolerated by goats and 8 ml of serum was found to protect goats against 4 ml of pooled virulent PPR virus. A durable active immunity was conferred on goats when serum and virulent PPR virus were given simultaneously. Passive immunity lasted for 15 days.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002417:Cattle; D006041:Goats / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D007110:Immunity, Active; D007114:Immunization / Q000662:veterinary*; D007116:Immunization, Passive / Q000662:veterinary*; D012301:Rinderpest / Q000276:immunology / Q000517:prevention & control*; D012302:Rinderpest virus / Q000276:immunology*
D000914:Antibodies, Viral; D007106:Immune Sera