[Calculation of Steel's cell loss factor and cell kinetic parameters for a population with exponential growth of cell number and cell death in the G1 and/or G0 phase with probabilities less than 1].
The method of calculation of the proliferative pool and of the Steel's loss factor was shown to be the same for the exponential growth state with cell death at the G1-phase and/or at the G0-phase with propabilities less than one (the model of F type), and for the exponential growth state model of C type. A method is proposed for calculation of the number of the cell kinetics parameters on the data of percentage of labeled cells cultivated with 3H-thymidine. An unsatisfactory agreement between the exponential growth state model of F type with the interpretation of the experimental of Drewinco e. a. (1978) was shown. A more satisfactory explanation of these data has been offered.
D002452:Cell Count; D002453:Cell Cycle; D002455:Cell Division; D002470:Cell Survival; D002478:Cells, Cultured; D007399:Interphase; D008954:Models, Biological; D011336:Probability
Raschet faktora kletochnykh poter' Stila i nekotorykh parametrov kletochnoĭ kinetiki dlia populiatsii s éksponentsial'nym rostom chisla kletok i gibel'iu kletok v faze G1 i (ili) v faze G0 s veroiatnostiami, men'shimi 1.