Ocular changes in patients undergoing long-term desferrioxamine treatment.
In a group of young patients with thalassaemia and iron overload treated by subcutaneous infusions of desferrioxamine we have found a number of minor alterations in retinal function. The incidence of such changes is not related to drug dosage or to ferritin level but to abnormality of the extended glucose tolerance test.
D000293:Adolescent; D000328:Adult; D002648:Child; D003676:Deferoxamine / Q000009:adverse effects* / Q000627:therapeutic use; D004585:Electrooculography; D004596:Electroretinography; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000139:chemically induced* / Q000503:physiopathology; D013789:Thalassemia / Q000188:drug therapy*
D003676:Deferoxamine