Colonic inhibition of cholecystokinin release and pancreatic protein secretion in dogs.
We have shown that the colon is capable of exerting profound inhibition on pancreatic enzyme secretion. This inhibition is brought about, at least in part, by significant suppression of release of cholecystokinin. Pancreatic polypeptide does not appear to be involved in colonic inhibition of pancreatic secretion.
D000818:Animals; D002766:Cholecystokinin / Q000097:blood / Q000378:metabolism*; D003106:Colon / Q000201:enzymology / Q000502:physiology*; D003314:Corn Oil; D004285:Dogs; D004386:Duodenum / Q000502:physiology; D009821:Oils / Q000008:administration & dosage; D009829:Oleic Acids; D010179:Pancreas / Q000378:metabolism*; D010191:Pancreatic Polypeptide / Q000097:blood / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D011863:Radioimmunoassay; D013997:Time Factors
D009821:Oils; D009829:Oleic Acids; D011506:Proteins; D010191:Pancreatic Polypeptide; D003314:Corn Oil; D002766:Cholecystokinin