[Facial vasomotor flushing due to alcohol-chlorpropamide. Prevalence in diabetic and non-diabetic patients].
Using a standard test (sherry 40 ml 12 hours and 36 hours after 250 mg chlorpropamide), chlorpropamide-alcohol flush (CPAF) prevalence was 34 p. 100 (19/56) in non insulin-dependent diabetics (NIDD), 10 p. 100 (3/30) in insulin-dependent diabetics and 7 p. 100 (2/27) in controls. Family history of diabetes was not associated with CPAF trait. Conflicting results in the literature might be explained by bias in patients selection or methodology.
D000328:Adult; D000368:Aged; D002747:Chlorpropamide / Q000009:adverse effects*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D004347:Drug Interactions; D000431:Ethanol / Q000009:adverse effects*; D005260:Female; D005483:Flushing / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D000431:Ethanol; D002747:Chlorpropamide
Bouffée vasomotrice faciale (flush) à l'alcool-chlorpropamide. Prévalence chez les diabétiques et les non-diabétiques.