Absorption kinetics of oxalate from oxalate-rich food in man.
The absorption of oxalate was investigated in a healthy subject after ingestion of oxalate-rich meals (spinach and rhubarb) with and without addition of 14C-labeled oxalic acid and calcium oxalate, and after oxalate-free meals with addition of nonlabeled sodium oxalate and calcium oxalate. Under these conditions, calcium oxalate was absorbed to the same extent as soluble oxalate; only a small percentage (2.4 +/- 0.7) of the total oxalate load was absorbed. Significant oxalate absorption occurred within 1 to 8 h after ingestion. The results suggest that under normal conditions the proximal part of the small bowel is a major absorption site.
D000328:Adult; D002129:Calcium Oxalate / Q000378:metabolism; D002250:Carbon Radioisotopes; D004032:Diet; D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D008297:Male; D010070:Oxalates / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D019815:Oxalic Acid; D014675:Vegetables
D002250:Carbon Radioisotopes; D010070:Oxalates; D002129:Calcium Oxalate; D019815:Oxalic Acid