title: Fluorescence histochemical study on the noradrenergic control to the anterior column of the spinal lumbosacral segments of the rat and dog, with special reference to motoneurons innervating the perineal striated muscles (Onuf's nucleus).
abstract: The organization of noradrenergic fibers in the lumbosacral anterior column of rats and dogs was examined in detail using a modification of a highly sensitive glyoxylic acid fluorescence histochemical method. In both rat and dog, there were greater concentrations of fluorescing noradrenergic fibers around the motoneurons innervating the perineal striated muscles (Onuf's nucleus) than around other motoneuronal groups. The preferential accumulation of noradrenergic fibers in Onuf's nucleus may indicate that the noradrenergic neuron system in the spinal cord of rodents and carnivores is closely related to the functional peculiarities of the perineal striated muscles, including the external anal and urethral sphincter muscles.
mesh_terms: D000818:Animals; D004285:Dogs; D006651:Histocytochemistry; D008161:Lumbosacral Region; D008297:Male; D008856:Microscopy, Fluorescence; D009046:Motor Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D010502:Perineum / Q000294:innervation*; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D013116:Spinal Cord / Q000378:metabolism*
chemical_list: D009638:Norepinephrine