title: Erythema nodosum.
abstract: This self-limiting disease is characterized by painful, red, cutaneous and subcutaneous nodules, and is often a manifestation of a systemic illness. Sarcoidosis, tuberculosis, coccidioidomycosis, streptococcal infections, inflammatory bowel disease and several drugs can be associated. The lesions, usually on the lower extremities, evolve from raised and tender nodules to a bruised appearance to complete resolution. The prognosis of the skin lesions is excellent, but the clinician's attention must be directed toward the presence of an underlying disease process.
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000150:complications; D003047:Coccidioidomycosis / Q000150:complications; D003937:Diagnosis, Differential; D064420:Drug-Related Side Effects and Adverse Reactions; D004893:Erythema Nodosum / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012507:Sarcoidosis / Q000150:complications; D014376:Tuberculosis / Q000150:complications
chemical_list: D000893:Anti-Inflammatory Agents