Multiple melanomas occurring in a patient with xeroderma pigmentosum.
Xeroderma pigmentosum (XP) is associated with an increased frequency of cutaneous malignancies including malignant melanoma. We report a patient who developed eleven primary melanomas and numerous highly atypical nevi in addition to the basal cell carcinomas and squamous cell carcinomas more commonly seen in patients with XP.
D000328:Adult; D002280:Basal Cell Carcinoma / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008545:Melanoma / Q000473:pathology* / Q000556:secondary; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology* / Q000556:secondary; D014983:Xeroderma Pigmentosum / Q000473:pathology*