title: [Changes in the biochemical indices of workers exposed to vinyl chloride and dichloroethane].
abstract: Complex laboratory investigations were carried out to 280 workers from a plant, exposed to vinylchloride and dichlorethane. Some hematological indices were followed up (hemoglobin, erythrocytes, leukocytes and platelets) and liver function (GGTP, GOT, GPT, AP, OCP and blood glutathione). Again GGTP and blood platelets significance was confirmed as a diagnostic sign of VCh disease. The inhibitory effect of VCh upon the OCP in the workers exposed is confirmed for the first time. OCP is proposed to be included in Instruction 099. A new case of VCh disease was diagnosed, where the combined effect of VCh and dichlorethane is admitted.
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects / Q000032:analysis; D001769:Blood / Q000187:drug effects*; D004357:Drug Synergism; D004781:Environmental Exposure; D005025:Ethylene Dichlorides / Q000506:poisoning*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000506:poisoning*; D008099:Liver / Q000187:drug effects*; D008111:Liver Function Tests; D014752:Vinyl Chloride / Q000009:adverse effects*; D014753:Vinyl Compounds / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D005025:Ethylene Dichlorides; D006843:Hydrocarbons, Chlorinated; D014753:Vinyl Compounds; C024565:ethylene dichloride; D014752:Vinyl Chloride
vernacular_title: Promeni v niakoi biokhimichni pokazateli pri rabotnitsi, eksponirani na vinilkhlorid i dikhloretan.