Urinary thiamine excretion after oral physiological doses of the vitamin.
Urinary thiamine excretion has been measured in healthy subjects after oral physiological doses of the vitamin. There was a highly significant correlation between the oral dose and the urinary excretion. However, there was considerable overlap between the baseline values and the urinary excretion following doses up to 1000 micrograms. It is recommended that repeated daily measurements are made to differentiate baseline excretion from that recorded after oral physiological doses. This study may have relevance to the monitoring of dietary fortification programmes with thiamine.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D012044:Regression Analysis; D013831:Thiamine / Q000008:administration & dosage / Q000652:urine*
D013831:Thiamine