Fibrinopeptide A in the diagnosis and treatment of deep venous thrombosis and pulmonary embolism.
The assay of fibrinopeptide A (FPA) has stimulated particular interest because of its high sensitivity and unique specificity for the action of thrombin. It has proved to be an extremely useful tool in research studies concerning the pathophysiology of thrombotic disease. Use of FPA in the diagnosis and treatment of deep venous thrombosis and pulmonary embolism is reviewed, and the potential usefulness of measuring FPA in the monitoring of the effectiveness of anticoagulant therapy is discussed.
D001793:Blood Preservation; D005340:Fibrinogen / Q000097:blood*; D005344:Fibrinopeptide A / Q000097:blood* / Q000378:metabolism; D006801:Humans; D011655:Pulmonary Embolism / Q000097:blood* / Q000628:therapy; D013048:Specimen Handling; D013924:Thrombophlebitis / Q000097:blood*; D013927:Thrombosis / Q000628:therapy
D005344:Fibrinopeptide A; D005340:Fibrinogen