Effectiveness of bornaprine on parkinsonian tremor.
The effectiveness of Bornaprine on parkinsonian tremor was evaluated in a single-blind study of medium-term treatment. 25 patients were treated with rising doses of Bornaprine per os, one week at each dose-level. The dose at which Bornaprine was most effective was 8 mg daily and its action at this dose was mild but statistically significant. The drug was generally well tolerated in patients with idiopathic parkinsonism, but transient confusion developed in a few patients with secondary parkinsonism.
D000328:Adult; D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D001952:Bridged-Ring Compounds / Q000627:therapeutic use*; D002561:Cerebrovascular Disorders / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D010302:Parkinson Disease, Secondary / Q000188:drug therapy; D014202:Tremor / Q000188:drug therapy*
D000978:Antiparkinson Agents; D001952:Bridged-Ring Compounds; C006088:bornaprine