[Is 0.5% bupivacaine solution isobaric?].
Bupivacaine 0.5% 3 ml was administered by subarachnoid injection to 100 patients. They were divided to four equal groups, according to the body position immediately following the injection: horizontal supine and lateral, sitting and Trendelenburg position. 15 min after the injection was the median dermatome in the later group at T 8.64, and after 60 min at T 7.44 level. The corresponding values for sitting patients were T 5.48 respect. T 3.08. It was concluded that subarachnoidally applied bupivacaine 0.5% shows hypobaric characteristics. This is in agreement with already reported in vitro determinations.
D002045:Bupivacaine / Q000008:administration & dosage* / Q000378:metabolism; D006801:Humans; D007267:Injections; D009407:Nerve Block; D011187:Posture; D013346:Subarachnoid Space; D013997:Time Factors
D002045:Bupivacaine
Ist 0,5% ige Bupivacaine-Lösung isobar?