Fatal hepatoadrenal necrosis in the neonate associated with echovirus types 11 and 12 presenting as a surgical emergency.
Two neonates presented to our service with suspected intraabdominal surgical emergencies. Both subsequently were found to have hepatoadrenal necrosis due to overwhelming echoviral infection. Echovirus types 11 and 12 were isolated postmortem. The latter virus has not been associated previously with fulminant neonatal illness.
D000307:Adrenal Gland Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000311:Adrenal Glands / Q000473:pathology; D004457:Echovirus Infections / Q000473:pathology / Q000601:surgery; D004630:Emergencies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D009336:Necrosis