[Contrast medium elimination by hemodialysis].
In 6 patients with no apparent kidney function the elimination of contrast medium was examined using 125I-labelled diatrizoic acid. Also blood level time curves and concentrations of dialysate were measured, showing a biexponential fall. The kinetic data established by computer-aided analysis according to the two-compartment model yielded elimination values not achieved by a healthy kidney; however a maximum elimination rate of 80.7 +/- 4.7% of the dose administered was calculated for a dialysis period of more than 10 hours. As the contrast medium plasma level was reduced the efficacy of haemodialysis fell.
D003287:Contrast Media / Q000378:metabolism*; D003973:Diatrizoate / Q000378:metabolism*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D007700:Kinetics; D008657:Metabolic Clearance Rate; D006435:Renal Dialysis
D003287:Contrast Media; D003973:Diatrizoate
Kontrastmittel-Elimination durch Hämodialyse.