[Action of the salts of univalent thallium on the liver mitochondria of the rat].
Using light scattering and electron microscopic techniques, studies have been made of the swelling of liver mitochondria in isotonic sucrose solutions containing different concentrations of nitrate or acetate of monovalent thallium. It was concluded that the injurious effect of thallium on the mitochondria is associated with both its penetration into intramitochondrial space, and interaction of the external thallium with mitochondrial membranes.
D000818:Animals; D066298:In Vitro Techniques; D007552:Isotonic Solutions; D008027:Light; D008854:Microscopy, Electron; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000648:ultrastructure; D008933:Mitochondrial Swelling / Q000187:drug effects; D009942:Organometallic Compounds; D051381:Rats; D012542:Scattering, Radiation; D013793:Thallium / Q000494:pharmacology*
D007552:Isotonic Solutions; D009942:Organometallic Compounds; D013793:Thallium; C042172:thallium nitrate; C026995:thallium acetate
Deĭstvie soleĭ odnovalentnogo talliia na mitokhondrii pecheni krysy.