[Effect of levorin on RNA synthesis in Ehrlich ascites carcinoma cells].
The polyene antibiotic levorin had no effect on the incorporation of 14C-uracil into the pool of intracellular free nucleotides in Ehrlich ascites tumour cells. RNA synthesis was inhibited by the antibiotic only at the late stages of incubation, evidently, due to earlier disturbances of the protein synthesis and in cell energetics.
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002478:Cells, Cultured; D051379:Mice; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D014498:Uracil / Q000378:metabolism
D000935:Antifungal Agents; D012334:RNA, Neoplasm; D002174:Candicidin; D014498:Uracil
Vliianie levorina na sintez RNK v kletkakh astsitnogo raka Erlikha.