title: Possibilities for an extended classification of bladder cancer.
abstract: Patients with bladder cancer were evaluated for T-class, histo-pathological grade and U-CEA (urinary carcinoembryonic antigen) before treatment and the cytological picture 4 months after treatment. Previous work has shown that these variables are not significantly intercorrelated. Scores were computed, consisting of the sums of these (dichotomized) variables. In a statistical analysis with the life-table technique, the scored variables have been log-rank tested for a prognostic trend. In 155 patients, p for symptom-free survival between subgroups with low and high scores was 0.0019 and for relative survival 0.0005. This implies that a combination of variables may have predictive value in bladder cancer.
mesh_terms: D000206:Actuarial Analysis; D002272:Carcinoembryonic Antigen / Q000652:urine*; D002277:Carcinoma / Q000401:mortality / Q000473:pathology* / Q000652:urine; D006801:Humans; D011379:Prognosis; D011863:Radioimmunoassay; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology* / Q000652:urine
chemical_list: D002272:Carcinoembryonic Antigen