title: Toxicologic studies associated with the agricultural use of municipal sewage sludge and health effects among sewage treatment plant workers.
abstract: The proposed use of municipal sewage sludges as soil amendments on agricultural land involves potential health risks. Sludges may contain toxic heavy metals, synthetic organics, and pathogens. Studies of animals inhabiting sludge-amended soils, or foraging on crops grown on such soils, have shown an increased deposition of cadmium and polychlorinated biphenyls in animal tissues, hepatic microsomal enzyme induction, altered blood profiles, appearance of mutagens in blood and excreta, and lowered feed intake, feed efficiency, and milk production. Epidemiologic evidence of possible adverse health effects among sewage plant workers exposed to aerosolized pathogens or synthetic organic vapors during wastewater treatment or land spreading of sludge is still inconclusive. Other possible deleterious environmental effects include pollution of groundwater and toxicity to birds consuming worms or insects inhabiting sludge-treated soils.
mesh_terms: D000383:Agriculture; D000821:Animal Feed; D000818:Animals; D004812:Epidemiologic Methods; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced*; D012722:Sewage; D012989:Soil Pollutants / Q000633:toxicity*
chemical_list: D012722:Sewage; D012989:Soil Pollutants