A supernumerary microchromosome in amniotic cell cultures and talipes equinovarus in a live born female.
Amniocentesis for advanced maternal age resulted in the demonstration of a supernumerary microchromosome in the amniotic fluid cells. Cytogenetic analysis of peripheral blood from the female infant revealed a mosaic karyotype 46,XX/47,XX, + marker. The only anomaly noted in the infant was talipes equinovarus.
D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D003025:Clubfoot / Q000235:genetics*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008423:Maternal Age; D009030:Mosaicism; D011247:Pregnancy; D011296:Prenatal Diagnosis