[Iodine-containing hormones--dipole modifiers of phospholipid membranes].
The hormones of thyroid gland thyroxine and triiodothyronine were shown to increase the permeability of bilayer lipid membrane (BLM) and inner mitochondrial membrane for hydrophobic positively charged complex K+-nonactine and to decrease the permeability of these membranes for hydrophobic anion FCCP-. These facts imply that the thyroid hormones affect the phospholipid membranes like the dipole modifyers decreasing the positive potential of hydrophobic region of the membranes in respect to the water phase.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D066298:In Vitro Techniques; D007700:Kinetics; D008051:Lipid Bilayers; D008930:Mitochondria, Liver / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects; D010693:Phloretin / Q000494:pharmacology; D051381:Rats; D013974:Thyroxine / Q000494:pharmacology*; D014284:Triiodothyronine / Q000494:pharmacology*
D008051:Lipid Bilayers; D014284:Triiodothyronine; D013974:Thyroxine; D010693:Phloretin
Iodosoderzhashchie gormony--dipol'nye modifikatory fosfolipidnykh membran.