title: Cerebral function in hyperthyroid patients. Psychopathology, psychometric variables, central arousal and time perception before and after thyreostatic therapy.
abstract: Psychopathology, psychometric variables, central arousal and time experience were studied in 30 hyperthyroid female outpatients. While these patients could be significantly discriminated in several of the above-described measures during the acute state of the disease, the intergroup differences disappeared after thyreostatic therapy. The thyroxine level was correlated with elevated beta-activity and the latter with variables of psychopathology and time experience. Hormonal dysbalance in hyperthyroidism is discussed as a biological substrate for neurophysiological changes which in turn causes deterioration in mood and behavior.
mesh_terms: D000328:Adult; D001143:Arousal / Q000187:drug effects; D004569:Electroencephalography; D005260:Female; D005425:Flicker Fusion / Q000187:drug effects; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000523:psychology*; D008713:Methimazole / Q000627:therapeutic use; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000523:psychology*; D011599:Psychopathology; D013998:Time Perception / Q000187:drug effects; D014145:Trail Making Test
chemical_list: D008713:Methimazole