title: [Contribution of nocturnal polygraphy to the diagnosis of Pickwickian syndrome. 10 cases].
abstract: The authors studied a series of 10 obese patients with respiratory failure referred for treatment because of sleep disorders and diurnal, sometimes uncontrollable, episodes of somnolence. 8 parameters were recorded in the polygraphic study performed during a night of hospitalization: electroencephalogram, electrocardiogram, electro-oculogram, chin electromyogram, thoracic movements, and nasal and buccal air flows. SaO2 and transcutaneous PO2 were recorded simultaneously. A sleep apnea syndrome was diagnosed in 6 of the 10 patients, whose apnea index was markedly above the limit of 5 apneas per hour. The apnea index was below 5 in the other 4 patients. Most patients with sleep apnea syndrome suffer from obstructive apneas of varying duration taking up as much as 48% of total sleep time. The cardiorespiratory effects of these events are apparent, with a drop in PO2 and SaO2 and a decrease in heart rate at the end of apnea. Polygraphic studies seem useful in the diagnosis of the pickwickian syndrome. They allow the type of apnea and its effects to be specified and thus guide treatment.
mesh_terms: D000368:Aged; D005260:Female; D006321:Heart / Q000503:physiopathology; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D010845:Obesity Hypoventilation Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D012137:Respiratory System / Q000503:physiopathology; D012890:Sleep / Q000502:physiology; D012891:Sleep Apnea Syndromes / Q000503:physiopathology
vernacular_title: Apport de la polygraphie nocturne au diagnostic du syndrome de Pickwick. A propos de 10 observations.