title: Photoreceptoral basis for altered dark-adaptation in retinal degeneration (RCS) rats.
abstract: The 'fast PIII' rod mediated photoreceptor response to flashes of monochromatic light has been investigated in isolated retinae of the RCS rat at age 30 days. A loss of both sensitivity and maximum response amplitude were found, with a concurrent slowing of the response kinetics. These observations indicate a rod abnormality which may underly the altered adaptational properties in these retinae.
mesh_terms: D000818:Animals; D003623:Dark Adaptation; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D066298:In Vitro Techniques; D008297:Male; D010786:Photoreceptor Cells / Q000503:physiopathology*; D051381:Rats; D011922:Rats, Mutant Strains; D012162:Retinal Degeneration / Q000503:physiopathology*