title: Liquid chromatographic determination of phenol and cresols in total particulate matter of cigarette smoke.
abstract: The phenol and cresol contents of the total particulate matter of tobacco smoke can be conveniently determined. A simple extraction procedure using 1N base is followed by partial neutralization with glacial acetic acid and elution of hydroxybenzenes from an end-capped reverse phase liquid chromatographic column. The procedure is rapid (20 min/sample after the initial extraction), precise (+/- 10% relative standard deviation), accurate, and convenient. Normally, 12 or fewer cigarettes are needed for a single measurement.
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods; D003408:Cresols / Q000032:analysis*; D019800:Phenol; D010636:Phenols / Q000032:analysis*; D012906:Smoke / Q000032:analysis; D012907:Smoking
chemical_list: D003408:Cresols; D010636:Phenols; D012906:Smoke; D019800:Phenol