Selenium content and glutathione peroxidase activity in tissues of the dairy cow after short-term feeding.
The effect of selenium and vitamin E on concentrations of selenium and selenium-dependent glutathione peroxidase in tissues of dairy cows was studied. Selenium (5 mg/day) and vitamin E (2 g/day) were supplemented for 10 days in a 2 X 2 factorial arrangement. Selenium supplementation increased content of selenium in whole blood, plasma, ovary, and liver and increased activity of selenium-dependent glutathione peroxidase in liver. Activity of selenium-dependent glutathione peroxidase in follicular fluid was closely correlated with selenium-dependent glutathione peroxidase in plasma. Significant activity of selenium-dependent glutathione peroxidase was detected in luteal tissue of the ovary. Relationships were linear between content of selenium and selenium-dependent glutathione peroxidase in ovary, uterus, and adrenal tissues.
D000284:Administration, Oral; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D003338:Corpus Luteum / Q000378:metabolism; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D010053:Ovary / Q000378:metabolism; D020887:Selenious Acid; D012643:Selenium / Q000008:administration & dosage* / Q000097:blood / Q000378:metabolism*; D024505:Tocopherols; D014599:Uterus / Q000378:metabolism; D014810:Vitamin E / Q000008:administration & dosage / Q000031:analogs & derivatives*; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
D014810:Vitamin E; D005979:Glutathione Peroxidase; D020887:Selenious Acid; D024502:alpha-Tocopherol; D012643:Selenium; D024505:Tocopherols