title: [Physico-chemical properties of IgG characteristic for normal growth].
abstract: It is shown that IgG typical of the normal growth appears in blood of rats with the regenerating liver and in pregnant ones and its capacity to form complexes with alpha-globulins insoluble in acid medium, isoelectric point and molecular mass are similar to these features in IgG typical of the malignant growth. At the same time hydrophobic properties and energy stability of this protein are close to those of IgG in control animals. The accessibility of ionogenic groups for titration in the studied protein varies like that observed in IgG typical of the malignant growth but is less pronounced. The data obtained evidence for the fact that subpopulations of IgG molecules with similar but not identical properties appear in blood of animals with the normal and malignant growth.
mesh_terms: D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006863:Hydrogen-Ion Concentration; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000032:analysis*; D007525:Isoelectric Focusing; D008115:Liver Regeneration; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000097:blood*; D011487:Protein Conformation; D051381:Rats
chemical_list: D007074:Immunoglobulin G; D011257:Pregnancy Proteins
vernacular_title: Fiziko-khimicheskie svoĭstva IgG, kharakternogo dlia normal'nogo rosta.