title: [ERG and VECP in chronic progressive external ophthalmoplegia].
abstract: Eleven patients suffering from chronic progressive external ophthalmoplegia (CPEO) were examined by means of electroretinography (ERG) and the visually evoked cortical potential (VECP) with flash and checkerboard-reversal stimuli. One patient exhibited a Kearns-Sayre syndrome, and in two patients fundoscopy revealed pigmentary retinopathy; the fundi of the other 8 patients were normal. In 3 of the patients with pigmentary retinopathy the ERG was slightly disturbed or normal, the P100 latency in the VECP being normal. In three out of 8 patients without retinal pigmentary changes the ERG indicated retinopathy. In 2 cases this was the only finding offering an explanation for the reduced visual acuity. One patient exhibited a considerably prolonged P100 latency in the pattern-reversal VECP of one eye, which might have been indicative of lesions of the visual pathway associated with CPEO.
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003623:Dark Adaptation; D004596:Electroretinography / Q000379:methods*; D005074:Evoked Potentials, Visual; D006801:Humans; D007625:Kearns-Sayre Syndrome / Q000175:diagnosis; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000175:diagnosis*; D010775:Photic Stimulation; D014792:Visual Acuity; D014794:Visual Fields
vernacular_title: ERG und VECP bei chronisch-progressiver externer Ophthalmoplegie.