Widespread osteolytic lesions of the long bones in basal cell nevus syndrome.
Three members of a family, father, daughter, and son, with the basal cell nevus syndrome are presented. A very unusual manifestation of widespread cyst-like osteolytic lesions in all the tubular bones was observed in the father, together with osteoblastic spotty "osteopoikilotic" lesions in the skull and the mandible of the same patient. Cyst-like osteolytic lesions have been described previously in this syndrome, mainly in the phalanges. We believe that such lesions can occur in any bone.
D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics; D001862:Bone Resorption / Q000000981:diagnostic imaging*; D002280:Basal Cell Carcinoma / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000235:genetics; D011859:Radiography