Effect of intramuscular atropine and glycopyrrolate on the cardiovascular response to tracheal intubation.
The effect of premedication with intramuscular atropine and glycopyrrolate on the cardiovascular changes resulting from the performance of laryngoscopy and tracheal intubation has been evaluated in two groups of 25 patients undergoing surgery. Neither atropine nor glycopyrrolate attenuated the hypertensive and tachycardic response to laryngoscopy and intubation; both significantly enhanced it (P less than 0,05).
D000293:Adolescent; D000328:Adult; D001285:Atropine / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006024:Glycopyrrolate / Q000494:pharmacology*; D006801:Humans; D007442:Intubation, Intratracheal; D007828:Laryngoscopy; D008297:Male; D008614:Meperidine / Q000494:pharmacology; D008875:Middle Aged; D011229:Preanesthetic Medication; D011398:Promethazine / Q000494:pharmacology; D011674:Pulse / Q000187:drug effects*; D011759:Pyrrolidines / Q000494:pharmacology*; D013997:Time Factors
D011759:Pyrrolidines; D001285:Atropine; D008614:Meperidine; D011398:Promethazine; D006024:Glycopyrrolate