title: Observations on serological cross-reactions between smooth Brucella species and organisms of other genera.
abstract: Serological cross-reactions have been demonstrated between smooth Brucella species and Escherichia coli 0:116 and 0:157, Salmonella serotypes of Kauffmann-White group N, Pseudomonas maltophilia and Yersinia enterocolitica 0:9 and 0:16. All of these organisms may evoke significant titres of cross-reacting antibodies in cattle and pigs inoculated by parenteral routes. E. coli 0:157, Salmonella urbana and Y. enterocolitica 0:9 evoked substantial titres of cross-reacting antibodies in cattle inoculated by the oral route with live organisms. Only Y. enterocolitica 0:9 was effective in evoking cross-reacting antibodies to Brucella in pigs inoculated by the same route. Differentiation of cross-reacting and homologous antibodies to Brucella was difficult and was not accomplished consistently by any single test.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002002:Brucella / Q000276:immunology*; D002006:Brucellosis / Q000175:diagnosis / Q000662:veterinary; D002007:Brucellosis, Bovine / Q000175:diagnosis; D002417:Cattle; D003429:Cross Reactions; D011549:Pseudomonas / Q000276:immunology; D012475:Salmonella / Q000276:immunology; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis; D015008:Yersinia enterocolitica / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial