In vivo 13C nuclear magnetic resonance spectroscopy using a solenoid transmit/receiver coil.
Topical nuclear magnetic resonance spectroscopy (NMR) using a solenoid transmit/receiver coil has been used to monitor the kinetics of intragastric utilization of [1-13C] glucose in mice in vivo. Using a double-tuned solenoid coil, signal to noise response was excellent and the natural abundance in vivo 13C spectra obtained with acquisition times of 10-15 minutes compares more than favourably with comparable studies using surface or saddle coils. This study clearly shows the potential of solenoid coils to monitor the kinetics of 13C-labelled metabolites in vivo.
D000818:Animals; D002247:Carbon Isotopes; D005753:Gastric Mucosa / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D007408:Intestinal Absorption; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation* / Q000379:methods; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains
D002247:Carbon Isotopes; D005947:Glucose