Comparative study of actuarial survival rates in P3 P4 (N+ Mo) transitional cell carcinoma of bladder managed by total cystectomy alone or associated with preoperative radiotherapy and pelvic lymphadenectomy.
In P3 P4 (N+ Mo) bladder cancer patients we conclude the following: 1) The addition of preoperative radiotherapy and meticulous pelvic cellulo-lymphadenectomy to total cystectomy has improved the actuarial survival at five years from 10.5% to 41%. 2) With this protocol, the pelvic recurrence has been reduced from 47.4% to 4.5% and presently the failures are due to undectectable distant metastases.
D000206:Actuarial Analysis; D002295:Carcinoma, Transitional Cell / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008197:Lymph Node Excision; D011300:Preoperative Care; D001749:Urinary Bladder Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery