title: Propranolol in the treatment of assaultive patients with organic brain disease.
abstract: Propranolol in doses up to 520 mg/day was administered to eight patients with organic brain disease characterized by violent and assaultive behavior refractory to conventional treatment. Improvement was demonstrated in the seven patients able to tolerate adequate drug dosages. Hypotension, bradycardia, and interactions with other medications constituted complications.
mesh_terms: D000328:Adult; D000368:Aged; D000374:Aggression; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy* / Q000523:psychology; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D011433:Propranolol