[Liver and kidney damage in rifampicin and ethambutol treatment].
Case report on a 40 years old patient with pulmonary tuberculosis, in whom a treatment with Rifampicin plus Ethambutol has caused a transient hepatic and renal failure. By histology a chronic aggressive hepatitis and a destruction of renal tubular epithelium could be found. The etiologic role of Rifampicin is believed to be probable. Pathomechanism and differential diagnosis are discussed.
D000328:Adult; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000009:adverse effects*; D006519:Hepatitis, Alcoholic / Q000150:complications / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D012293:Rifampin / Q000009:adverse effects*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy / Q000473:pathology
D004977:Ethambutol; D012293:Rifampin
Leber- und Nierenschädigung bei Rifampizin und Ethambutol-Behandlung.