Estradiol and progesterone receptors in gynecologic sarcomas.
We report the concentrations of estradiol and progesterone receptors found in the tumor tissue of 5 patients with leiomyosarcoma, 4 of uterine and one of ventricular origin, and of 5 patients with uterine or ovarian carcinosarcoma. Steroid receptor positive and negative tumors were present in both groups of sarcoma. One uterine leiomyosarcoma had a high concentration of estradiol and progesterone receptors, 37 fmoles/mg protein and 156 fmoles/mg protein, respectively. We suggest that steroid receptors should be analysed in all gynecologic sarcomas.
D000328:Adult; D000368:Aged; D002296:Carcinosarcoma / Q000032:analysis*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000032:analysis*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000032:analysis*; D011959:Receptors, Estradiol / Q000032:analysis*; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D013274:Stomach Neoplasms / Q000032:analysis; D014594:Uterine Neoplasms / Q000032:analysis*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone