[An aorto-esophageal fistula in a patient with malignant lymphogranuloma].
A 25-year-old man suffering from lymphogranuloma malignum received mediastinal radiotherapy in a dose of 3,380 R (827 mC/1 kg). About 2,5 years later fatal gastro-intestinal haemorrhage occurred from a aortooesophageal fistula. Aortic necrosis of media and intima with G+ cocci was found, as well as adventitial fibrosis with radiation fibroblasts. Assisting mechanisms of aortic damage by therapeutic doses of radiation were discussed.
D000328:Adult; D001018:Aortic Diseases / Q000209:etiology* / Q000473:pathology; D004937:Esophageal Fistula / Q000209:etiology* / Q000473:pathology; D005402:Fistula / Q000209:etiology* / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D008297:Male
Aortoezofageální pístĕl u nemocného maligním lymfogranulomem.