[Cryopreservation of human parathyroid tissue. Effect of in vitro secretory behavior and morphology].
The effects of cryopreservation on in vitro secretion and on the survival rate of parathyroid cells were investigated, in order to find possible causes for the frequent failure of autologous, human parathyroid tissue. A reduction in the hormone secretion or an influence on the secretion could be excluded. The freezing procedure, however, leads to a partial necrosis of the tissue. Similarly good results, as in the replantation of fresh tissue, can be achieved by compensating the necrotic cells using more particles.
D000236:Adenoma / Q000378:metabolism; D002478:Cells, Cultured; D003470:Culture Media; D005615:Freezing; D006801:Humans; D006961:Hyperparathyroidism / Q000378:metabolism; D006962:Hyperparathyroidism, Secondary / Q000378:metabolism; D009336:Necrosis; D009926:Organ Preservation; D010280:Parathyroid Glands / Q000378:metabolism / Q000473:pathology / Q000637:transplantation; D010281:Parathyroid Hormone / Q000378:metabolism; D010282:Parathyroid Neoplasms / Q000378:metabolism; D011863:Radioimmunoassay
D003470:Culture Media; D010281:Parathyroid Hormone
Kältekonservierung menschlichen Nebenschilddrüsen-Gewebes. Einfluss auf das In-vitro-Sekretionsverhalten und die Morphologie.