The effect of a single dose of metrifonate on Schistosoma haematobium infection in Egyptian school children.
Egyptian school children infected with Schistosoma haematobium and treated with a single dose of metrifonate, 10 mg/kg body weight, had a marked reduction in urine egg counts reaching 90% during a 30-week follow-up. While cure rate was higher among lightly infected persons, percentage reduction in egg counts was greater among the heavily infected. After a summer period of probable high risk exposure reinfection rate in those children who were treated and cured was 4.7% as compared to 6% in previously uninfected children.
D002648:Child; D004534:Egypt; D006801:Humans; D010270:Parasite Egg Count; D012548:Schistosoma haematobium; D012552:Schistosomiasis / Q000188:drug therapy* / Q000652:urine; D014236:Trichlorfon / Q000008:administration & dosage / Q000627:therapeutic use*
D014236:Trichlorfon