title: [Multifactorial malignancy analysis--modern knowledge in the practical diagnosis of head and neck tumors].
abstract: A pretherapeutical multi-step-check method of the diagnosis of malignancy is suggested as a basis of an individual therapy of tumours. It must comprise clinical tumour diagnosis (staging)--the tumour localizations, size and spreading of metastases--histopathological and histochemical grading of malignancy, and histological classification. Results of these diagnostic methods of 186 squamous-cell carcinomas of the head and neck were related to the survival rate. Histochemical LDH and G6PDH reactions and histopathological grading (G 1-group and G 3-group) are important criteria for prognosis.
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009367:Neoplasm Staging; D011379:Prognosis; D012106:Research; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase
vernacular_title: Multifaktorielle Malignitätsanalyse--moderne Erkenntnisse in der praktischen Diagnostik von Kopf-Hals-Tumoren.