title: Effect of premedication with diazepam, morphine or nalbuphine on gastrointestinal motility after surgery.
abstract: Premedication with nalbuphine and morphine delayed gastric emptying in the period after operation, but oral diazepam did not. All three drugs delayed co-ordinated intestinal motility, although nalbuphine did so for less than half as long as morphine. This property of nalbuphine, if confirmed, could make it a valuable analgesic drug in the period after operation.
mesh_terms: D000082:Acetaminophen / Q000097:blood; D000328:Adult; D003975:Diazepam / Q000494:pharmacology*; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D009019:Morphinans / Q000494:pharmacology*; D009020:Morphine / Q000494:pharmacology*; D009266:Nalbuphine / Q000494:pharmacology*; D011184:Postoperative Period; D011229:Preanesthetic Medication; D013997:Time Factors
chemical_list: D009019:Morphinans; D000082:Acetaminophen; D009020:Morphine; D009266:Nalbuphine; D003975:Diazepam