[Tracheal stenosis in the cat: anatomopathologic repercussions on the pulmonary parenchyma].
A calibrated stenosis of the trachea was performed in 6 young cats and 1 old one (TS cats); the animals were observed for 8 or 15 weeks thereafter. The percentage of macrophages in bronchoalveolar lavage fluid was greater in the TS cats than in the controls. An irregular distribution of pulmonary lesions was found. 4 TS cats presented with a real emphysema with tracheobronchial inflammation, a parenchymatous infection which was histologically shown or quantified in lavage fluid (Haemophilus (10(8]. They exhibited episodes of hypoventilation which followed in quick succession. The alveolar section of the TS emphysematous lung was equal or greater (up to 88% of the lung surface observed) than that of both the same-aged controls (81.5%) and of an old emphysematous cat (88 months). The alveoli were more homogeneous (lower deviation). TS lung was characterized by a higher amount of dry tissue protein but hydroxyproline varied individually. A possible synergy between infection and ventilatory obstruction may be a tentative explanation for the etiogeny of this emphysema which appears to be secondary to tracheal stenosis.
D000402:Airway Obstruction / Q000473:pathology; D000818:Animals; D002415:Cats; D005260:Female; D006192:Haemophilus Infections / Q000473:pathology; D007958:Leukocyte Count; D008168:Lung / Q000473:pathology*; D008264:Macrophages / Q000648:ultrastructure; D008297:Male; D011014:Pneumonia / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology; D011656:Pulmonary Emphysema / Q000473:pathology; D014135:Tracheal Stenosis / Q000473:pathology*
Sténose trachéale chez le chat: répercussions anatomo-pathologiques sur le parenchyme pulmonaire.