title: Genesis of the 'true' negative pressure in the lumbar epidural space. A new hypothesis.
abstract: A hypothesis is suggested that the initial or 'true' negative pressure encountered when a needle first enters the epidural space is due to initial bulging of the ligamentum flavum in front of the advancing needle followed by its rapid return to the resting position once the needle has perforated the ligament. The bulging has been confirmed to occur in fresh cadavers, and pressure studies carried out during performance of epidural blocks in patients lend weight to this hypothesis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D004547:Elastic Tissue / Q000502:physiology; D004824:Epidural Space / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011312:Pressure; D013115:Spinal Canal / Q000502:physiology*