Peripheral vasomotor control and menopausal flushing--a preliminary report.
Menopausal flushing can be considered as an intermittent loss of peripheral vasomotor control. Thermal entrainment testing has been used to assess the degree of peripheral vasomotor control in a preliminary study of seven women receiving oestrogen replacement therapy in the form of percutaneous cream. Significant improvement was demonstrated in the degree of control over a 3-month period in those patients who were symptomatically improved. We suggest that oestrogen exerts an influence on peripheral vasomotor control and flushes and sweats occur when this influence is removed.
D000287:Administration, Topical; D000328:Adult; D002979:Climacteric / Q000187:drug effects*; D003080:Cold Temperature; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008593:Menopause / Q000187:drug effects*; D008875:Middle Aged; D010865:Pilot Projects; D014666:Vasomotor System / Q000187:drug effects*
D004958:Estradiol