[Pancreatic cancer in father and daughter].
A 77-year-old male patient was admitted because of jaundice and general malaise. Exploratory laparotomy disclosed pancreatic head cancer with invasion to the intrapancreatic bile duct. Three months later, his daughter, aged 51, was admitted for evaluation because of body weight loss and back pain. CT scan disclosed 3 low-density areas in the pancreas with irregular margins and multiple low-density areas in the liver. Pancreatic cancer with liver metastasis was confirmed by autopsy. In familial pancreatic cancer, it is essential that genetic in addition to environmental factors be examined in pancreatic carcinogenesis.
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000235:genetics* / Q000473:pathology; D010375:Pedigree