title: [Influences of the biliary reconstructions by Roux-en Y method and jejunal interposition method on the gastric acid secretion in dogs].
abstract: This study was made to examine the influences on the gastric acid secretion and serum gastrin level after the oral administration of beef extract, and on the inhibitory mechanism of the gastric acid secretion after the intraduodenal injection of either lipid or glucose in dogs which had reconstructed biliary tract by means of either Roux-en Y cholecystojejunostomy or cholecystoduodenojejunostomy; jejunal interposition between the gallbladder and the duodenum. The excreted gastric acid secretion from Heidenhain pouch showed a slight increase after cholecystojejunoduodenostomy, while it increased significantly after Roux-en Y cholecystojejunostomy. The serum gastrin showed no significant changes after either reconstruction. The gastric acid secretion after the intraduodenal injection of glucose was inhibited almost to the degree before and after either reconstruction. The inhibitory effects on the gastric acid secretion after the intraduodenal injection of lipid were not observed after Roux-en Y cholecystojejunostomy but it was significantly inhibited after cholecystojejunoduodenostomy. It can be concluded from these results that jejunal interposition will be more suitable for the gastric acid secretion or its inhibitory mechanism than Roux-en Y type.
mesh_terms: D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000601:surgery*; D005260:Female; D005704:Gallbladder / Q000601:surgery*; D005744:Gastric Acid / Q000378:metabolism*; D005755:Gastrins / Q000097:blood; D005947:Glucose / Q000494:pharmacology; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008722:Methods
chemical_list: D005755:Gastrins; D005947:Glucose