Experimental investigations on the effect of desferrioxamine on the aqueous level of iron administered intraorbitally.
Rabbits with an iron foreign body in the orbit were given transconjunctival injections of desferrioxamine every 4th day. It was found that after 12 months the level of iron in the aqueous of their eyes was distinctly lower than in another group, which received no medication. Under the conditions of the experiment, desferrioxamine distinctly prevented extrabulbar iron from penetrating into the eyeball.
D000818:Animals; D001082:Aqueous Humor / Q000187:drug effects* / Q000378:metabolism; D003676:Deferoxamine / Q000008:administration & dosage / Q000494:pharmacology*; D005129:Eye Foreign Bodies / Q000188:drug therapy*; D007501:Iron / Q000378:metabolism*; D011817:Rabbits
D007501:Iron; D003676:Deferoxamine