Mucinous syringometaplasia.
This is a clinicopathologic study of six patients with mucinous syringometaplasia, which was diagnosed histologically. Biopsies revealed a focal invagination of the epidermis lined by squamous epithelium, with one or several eccrine ducts leading into the vagination. The eccrine duct epithelium contained mucin-laden goblet cells, and there was mucinous syringometaplasia of the underlying eccrine coils. This histopathologic change was associated with two types of clinical lesions: (1) verrucous lesions, consistent with those described by previous authors, and (2) lesions suggestive of basal cell carcinoma, which have not been described with this pathologic entity in previous publications.
D000293:Adolescent; D000328:Adult; D001913:Bowen's Disease / Q000175:diagnosis; D002280:Basal Cell Carcinoma / Q000175:diagnosis; D003937:Diagnosis, Differential; D004439:Eccrine Glands / Q000473:pathology*; D005385:Fingers; D006229:Hand Dermatoses / Q000175:diagnosis; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D011230:Precancerous Conditions / Q000175:diagnosis*; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis*; D013544:Sweat Gland Neoplasms / Q000175:diagnosis*; D013545:Sweat Glands / Q000473:pathology*; D014860:Warts / Q000175:diagnosis
D009077:Mucins