title: The gene for the adenovirus 2 hexon polypeptide.
abstract: The nucleotide sequence of the gene for the adenovirus type 2 hexon has been determined. The hexon polypeptide consists of 967 amino acid residues and has a molecular weight of 109,058. Several tentative parts in the previously reported amino acid sequence were resolved from the DNA sequence. The existence of regions with unusual properties in the hexon protein was confirmed, including a region consisting of 16 consecutive acidic residues in the N-terminal part of the protein. In conjunction with previously published sequences and sequences reported in the accompanying papers (Aleström, P., Akusjärvi, G., Lager, M., Yeh-Kai, L., and Petterson, U. (1984) J. Biol. Chem. 259, 13980-13985; Roberts, R. J., O'Neill, K. E., and Yen, C. E. (1984) J. Biol. Chem. 259, 13965-13975) a complete sequence of the 35,937-base pairs-long adenovirus type 2 genome can now be reconstructed.
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D000595:Amino Acid Sequence; D001483:Base Sequence; D002213:Capsid / Q000032:analysis / Q000235:genetics*; D036022:Capsid Proteins; D003488:Cyanogen Bromide; D004279:DNA, Viral / Q000032:analysis*; D010446:Peptide Fragments / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis
chemical_list: D036022:Capsid Proteins; D004279:DNA, Viral; D010446:Peptide Fragments; D012333:RNA, Messenger; C018315:hexon capsid protein, Adenovirus; D003488:Cyanogen Bromide