Effects of solvent medium on solubility III: Hydrophilic-lipophilic character exhibited by some functional groups having oxygen or nitrogen in ethanol-water.
Solubility data of nine derivatives of the structure p-X1-C6H4-X2 in ethanol-water at 25 degrees C are reported. The correlation of such sets of data by log Sy = Py X log Sx + C yields the medium effect parameter Py for a variety of functional groups possessing either oxygen or nitrogen. Py accounts for the hydrophilic-lipophilic character exhibited by each group.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D000431:Ethanol; D009584:Nitrogen; D010100:Oxygen; D012995:Solubility; D012997:Solvents; D014867:Water
D012997:Solvents; D014867:Water; D000431:Ethanol; D009584:Nitrogen; D010100:Oxygen