Liver function during chronic renal failure in rabbits.
In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.
D000410:Alanine Transaminase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D005690:Galactose / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000473:pathology / Q000503:physiopathology*; D008099:Liver / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D011517:Prothrombin Time; D011817:Rabbits
D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D005690:Galactose