title: [Regional hyperthermic cytostatic perfusion as an alternative in the treatment of malignant soft tissue tumors of the extremities].
abstract: From March 1979 through December 1983, 15 patients with soft-tissue sarcomas of the extremities were treated by a local excision and an adjuvant regional hyperthermic cytostatic perfusion. Reversible edema in two patients was the only post-operative complication. 14 patients were disease-free after a median follow-up period of 24.2 months. One female patient developed a local recurrence 10 months following surgery. Based on our results and long-term studies of several authors, the adjuvant regional perfusion appears capable of successfully treating patients with soft-tissue sarcomas of the extremities.
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001132:Arm; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D003131:Combined Modality Therapy; D003609:Dactinomycin / Q000008:administration & dosage; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007866:Leg; D008297:Male; D008558:Melphalan / Q000008:administration & dosage; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery
chemical_list: D003609:Dactinomycin; D008558:Melphalan
vernacular_title: Die regionale hypertherme Cytostaticaperfusion als Alternative bei der Behandlung von malignen Weichgewebstumoren der Extremitäten.