title: Early migration of immature Fasciola hepatica and associated liver pathology in cattle.
abstract: Immature Fasciola hepatica were successfully recovered from the body cavity of cattle from two to 21 days after oral infection. Flukes had penetrated the liver in large numbers by day 7 but there did not appear to be a corresponding reduction in the numbers recovered from the body cavity. Liver pathology showed a typical progressive tissue disruption with a neutrophil and lymphocyte infiltration by day 7 and a marked eosinophil response from day 14. The mesothelium of the liver capsule underwent metaplasia, becoming ultimately highly active and columnar.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology* / Q000473:pathology; D005210:Fasciola hepatica / Q000502:physiology*; D005211:Fascioliasis / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000469:parasitology / Q000473:pathology*; D008124:Locomotion; D008214:Lymphocytes / Q000166:cytology; D008297:Male; D009504:Neutrophils / Q000166:cytology; D010529:Peritoneal Cavity / Q000469:parasitology