Sensitizing potential of urethane (meth)acrylates in the guinea pig.
Urethane (meth)acrylates are used as prepolymers in ultraviolet-curable inks, varnishes and coating formulations for industrial purposes as well as resins for dental applications. The sensitizing capacity of 3 commonly used urethane (meth)acrylates was investigated using the guinea pig maximization test. The study shows that an aliphatic urethane acrylate is not only a more potent sensitizer than an aromatic one, but also more sensitizing than a (meth)acrylated aliphatic urethane.
D000179:Acrylates / Q000009:adverse effects*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006168:Guinea Pigs; D008689:Methacrylates / Q000009:adverse effects*; D010328:Patch Tests; D014520:Urethane / Q000009:adverse effects*
D000179:Acrylates; D008689:Methacrylates; D014520:Urethane