Cimetidine does not alter ibuprofen kinetics after a single dose.
Cimetidine does not slow the disappearance of ibuprofen from the serum after a single dose in healthy male volunteers. This suggests that no change in ibuprofen dosing is necessary when cimetidine is co-administered.
D000328:Adult; D002927:Cimetidine / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D007052:Ibuprofen / Q000378:metabolism*; D007700:Kinetics; D008297:Male
D002927:Cimetidine; D007052:Ibuprofen