[Phospholipid and malondialdehyde content in the cerebral cortex of rats with incomplete ischemia and in the postischemic period].
During severe incomplete brain ischemia caused by combined bilateral ligation of the general carotid arteries and blood pressure reduction to 50 Hg by blood withdrawal from the femoral artery, the cortex of cerebral hemispheres demonstrates, by the 60th minute of ischemia, a 15.4%-lowering of the content of total phospholipids (PL) and a 33.3%-increase in the content of malonyl dialdehyde (MDA). By the 30th minute of the postischemic period the content of total PL remains decreased, the content of monophosphoinositides (MPI) rises by 110.2%, whereas the content of MDA remains high. By the 60th minute of postischemia the content of total PL and MDA returns to the initial levels. However the content of MDA remains high as before.
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism*; D002546:Ischemic Attack, Transient / Q000378:metabolism*; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008314:Malonates / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D008054:Lipid Peroxides; D008314:Malonates; D010743:Phospholipids; D008315:Malondialdehyde
Soderzhanie fosfolipidov i malonildial'degida v kore bol'shikh polushariĭ mozga krys pri ego nepolnoĭ ishemii i v postishemicheskom periode.