title: Secondary agoraphobia: two case reports.
abstract: Two patients with agoraphobic symptoms and major depressive disorder exhibited dexamethasone nonsuppression. Antidepressant pharmacotherapy was associated with remission of depressive symptoms and DST normalization. This improvement predated remission of agoraphobic symptoms by 1-2 months. It is suggested that agoraphobia was secondary to the depression in both cases.
mesh_terms: D000368:Aged; D000379:Agoraphobia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000928:Antidepressive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003907:Dexamethasone; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D010698:Phobic Disorders / Q000209:etiology*
chemical_list: D000928:Antidepressive Agents; D003907:Dexamethasone; D006854:Hydrocortisone