title: Bupivacaine leak past inflated tourniquets during intravenous regional analgesia.
abstract: A small leak of bupivacaine was detected in 13 out of 52 cases (25%) during intravenous regional analgesia for the upper limb whilst the tourniquet cuff remained properly inflated. The plasma levels of bupivacaine (range 0.2-0.4 microgram/ml) were well below the toxic range, and no adverse sequelae resulted.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000765:Anesthesia, Conduction / Q000009:adverse effects*; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D002045:Bupivacaine / Q000009:adverse effects* / Q000097:blood; D005260:Female; D005542:Forearm / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014111:Tourniquets
chemical_list: D002045:Bupivacaine