Changes in intestinal blood flow during the development of chronic large bowel obstruction.
The effect of chronic progressive distal large bowel obstruction on intestinal blood flow was studied in 12 mini-pigs. Blood flow was measured by the techniques of xenon133 clearance and intracardiac injections of radiolabelled microspheres. Intestinal blood flow was increased in the left colon and ileum but decreased in the caecum. Blood was shunted from the mucosa to the muscle layers. The results suggest that primary anastomosis of the obstructed left colon is not contraindicated by haemodynamic considerations.
D000818:Animals; D002908:Chronic Disease; D003106:Colon / Q000601:surgery; D004195:Disease Models, Animal; D007415:Intestinal Obstruction / Q000503:physiopathology* / Q000601:surgery; D007420:Intestine, Large / Q000098:blood supply*; D008297:Male; D008863:Microspheres; D012039:Regional Blood Flow; D013552:Swine; D013556:Swine, Miniature; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes