Failure of chronic haloperidol treatment to alter levels of cholecystokinin in the rat brain striatum and olfactory tuberclenucleus accumbens area.
We have studied the effect of chronic haloperidol (HAL) treatment on CCK-8 levels in two rat brain regions. HAL administration using two different protocols, daily injections and infusion with subcutaneously implanted minipumps, did not produce any significant changes in CCK-8 levels in the striatum or olfactory tubercle-nucleus accumbens area.
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002766:Cholecystokinin / Q000032:analysis*; D003342:Corpus Striatum / Q000032:analysis; D006220:Haloperidol / Q000494:pharmacology*; D008297:Male; D009714:Nucleus Accumbens / Q000032:analysis; D009832:Olfactory Nerve / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
D002766:Cholecystokinin; D006220:Haloperidol