Spurious automated red cell values in warm autoimmune hemolytic anemia.
Two patients with warm autoantibodies to their red cells had a mean cell volume artifactually elevated by red cell agglutination. Red cell size distribution histograms directly showed doublets and triplets of normal-size red cells. This phenomenon is similar to the spurious macrocytosis previously reported due to cold agglutinins, but was not reversible by warming.
D000328:Adult; D000373:Agglutinins / Q000502:physiology; D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood*; D001322:Autoanalysis; D003450:Cryoglobulins; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000502:physiology*; D007075:Immunoglobulin M / Q000502:physiology; D008875:Middle Aged
D000373:Agglutinins; D003450:Cryoglobulins; D007074:Immunoglobulin G; D007075:Immunoglobulin M; C029443:cold agglutinins