Postsynaptic fibers reaching the dorsal column nuclei in the rat.
Postsynaptic fibers reaching the dorsal column nuclei were investigated in rat by means of retrograde transport of wheat germ agglutinin-horseradish peroxidase conjugate. Each nucleus received only ipsilateral afferents with most of the labeled cells forming a band which covered the mediolateral extent of the dorsal horn in an area that resembled lamina IV in the cat. The labeling excluded the reticular extension of the neck of the dorsal horn. Lumbosacral afferents were restricted to the gracilis nucleus and cervicothoracic afferents to the cuneatus nucleus. Cervical and anterior lumbar levels showed additional projections coming from their most medial parts. The organization of this second-order pathway in rat is similar to that in cat and monkey.
D000344:Afferent Pathways / Q000033:anatomy & histology; D000818:Animals; D008526:Medulla Oblongata / Q000033:anatomy & histology*; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000033:anatomy & histology*