title: Anticoagulants and abdominal pain. The role of computed tomography.
abstract: The development of abdominal pain in the patient receiving anticoagulants, especially with a documented drop in hematocrit levels, almost certainly indicates a major hemorrhage. If loss of blood from the GI tract is not documented, some form of internal bleeding must have occurred. Unfortunately, the site of the bleeding is frequently unclear. Even small hemorrhages in critical locations (eg, the adrenal gland) can have serious consequences. In the obese patient, a rectus sheath hematoma may remain hidden at the time of repeated physical examinations. Generally, the cause of a mass palpated or perhaps demonstrated by conventional radiological studies cannot be diagnosed accurately. Computed tomography can demonstrate the size and location of the mass and its relation to normal intra-abdominal structures. By careful evaluation of the attenuation coefficient, it is possible to establish the definitive diagnosis of hemorrhage. Should the attenuation value of a mass be insufficiently high to diagnose hemorrhage conclusively on the initial scan, serial scans demonstrating a decrease in size and/or attenuation of the mass confirm the diagnosis of hemorrhage. In our opinion a negative CT examination is a reliable indicator that such a bleeding complication has not occurred.
mesh_terms: D000208:Acute Disease; D000307:Adrenal Gland Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006406:Hematoma / Q000000981:diagnostic imaging; D006470:Hemorrhage / Q000139:chemically induced / Q000000981:diagnostic imaging*; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology*; D011860:Radiography, Abdominal; D012002:Rectal Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants