title: Flash induced nystagmus (FIN) in the rabbit: input-output relations.
abstract: Flash-induced nystagmus (FIN) was elicited by monocular flicker-stimulation at 20-40 Hz. It was found more often in albino than in pigmented rabbits. Slow phase velocity (SPV) showed a gradual increase, then a steady-state level in most animals and an after-response after cessation of stimulation. incremental and decremental phase mainly showed an exponential change in SPV. Apparent time constants were in the range of 5-40 sec. Simultaneous recording of both eyes revealed greater velocity and amplitude of both phases of FIN in the stimulated eye. FIN can be specified as a type of nystagmus that is evoked by monocular essentially open-loop stimulation of the crossed ("subcortical") visual pathway. Direction-selective elements in the retina may play a specific role and their predominant orientation gives rise to nystagmus in adducting direction in the flicker-stimulated eye as if it were exposed to optokinetic stimulation in the temporonasal direction.
mesh_terms: D000818:Animals; D002746:Chlorpromazine / Q000494:pharmacology; D004329:Droperidol / Q000494:pharmacology; D006200:Hair Color; D009760:Nystagmus, Physiologic / Q000187:drug effects; D010775:Photic Stimulation; D011817:Rabbits
chemical_list: D004329:Droperidol; D002746:Chlorpromazine