title: [Evaluation of the effect of flunitrazepam on the lower esophageal sphincter in man with intraluminal manometry].
abstract: The effect of Flunitrazepam on the human lower oesophageal sphincter is evaluated. Pressure in the LOS and GOR using the Acid Reflux Test was evaluated in 22 surgical cases at rest (after ingestions of a placebo and Flunitrazepam). The results obtained indicate that the LOS pressure variations induced by flunitrazepam significantly increase the probability of GOR.
mesh_terms: D004943:Esophagogastric Junction / Q000187:drug effects*; D005445:Flunitrazepam / Q000627:therapeutic use*; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000209:etiology; D006551:Hernia, Hiatal / Q000150:complications; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008365:Manometry / Q000379:methods*
chemical_list: D005445:Flunitrazepam
vernacular_title: Valutazione dell'effetto del flunitrazepam sullo sfintere esofageo inferiore dell'uomo con manometria intraluminale.