title: Failure of chronic haloperidol treatment to alter levels of cholecystokinin in the rat brain striatum and olfactory tuberclenucleus accumbens area.
abstract: We have studied the effect of chronic haloperidol (HAL) treatment on CCK-8 levels in two rat brain regions. HAL administration using two different protocols, daily injections and infusion with subcutaneously implanted minipumps, did not produce any significant changes in CCK-8 levels in the striatum or olfactory tubercle-nucleus accumbens area.
mesh_terms: D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002766:Cholecystokinin / Q000032:analysis*; D003342:Corpus Striatum / Q000032:analysis; D006220:Haloperidol / Q000494:pharmacology*; D008297:Male; D009714:Nucleus Accumbens / Q000032:analysis; D009832:Olfactory Nerve / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002766:Cholecystokinin; D006220:Haloperidol