[Liposome transport as a model of substance absorption in the small intestine studied by electron microscopic autoradiography and scanning microscopy].
Using electron microscope autoradiography and scanning microscopy, evidence was provided on the space-time character of the transport of enterally introduced liposomes containing 125I-lecitin and 3H-cholesterine. Liposomes underwent degradation on the mucous surface of the epithelial cells, followed by the appearance of monolayer vesicles to be transported to the glycocalix area between the microvilli. This is accompanied with the release of the radioactive trait from liposomes and its transporting to enterocytes.
D000818:Animals; D001345:Autoradiography; D001692:Biological Transport; D002784:Cholesterol / Q000378:metabolism; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism / Q000648:ultrastructure; D007421:Intestine, Small / Q000378:metabolism* / Q000648:ultrastructure; D008081:Liposomes / Q000378:metabolism*; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010713:Phosphatidylcholines / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D008081:Liposomes; D010713:Phosphatidylcholines; D002784:Cholesterol
Issledovanie transporta liposom v kachestve modeli vsasyvaniia veshchestv v tonkoĭ kishke metodom élektronno-mikroskopicheskoĭ avtoradiografii i skaniruiushcheĭ mikroskopii.