Parentage testing using the serum protein plasminogen (PLG).
Isoelectric focusing of plasminogen (PLG) was tested on a Minnesota population of 2,187 white individuals and 451 paternity cases. A total of six different PLG allotypes were observed PLG*1, PLG*2, PLG*3, PLG*B, PLG*D and PLG*M. Observed gene frequencies predicted a probability P = 0.2 of excluding men who were falsely determined to be parents. The observed frequency of PLG exclusions among all exclusions detected in the study using a test battery of 14-16 genetic markers was similar to the expected value. PLG phenotyping proved to be a very useful genetic marker system in routine parentage testing.
D002648:Child; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007525:Isoelectric Focusing / Q000379:methods*; D008297:Male; D010290:Parents; D010334:Paternity; D010641:Phenotype; D010958:Plasminogen / Q000032:analysis / Q000235:genetics*
D010958:Plasminogen