title: Sensorineural hearing loss in otitis media.
abstract: Additional evidence is presented to support the hypothesis that both acute purulent otitis media (POM) and chronic suppurative otitis media (COM) can cause high frequency sensorineural hearing loss. In selected patients and in animals (chinchillas) in a pilot study using electrophysiological methods, both temporary threshold shifts and permanent threshold shifts of basal cochlear turn involvement were demonstrated in POM. Data of cochlear involvement in 475 ears with bilateral COM, 607 ears with unilateral COM, and 607 ears serving as controls were obtained from six centers in five countries. In group 1 (15 dB or greater), 43% of ears with unilateral COM and 42% of ears with bilateral COM showed losses, for a combined odds ratio eight times that in controls. In group 2 (30 dB or greater), 16% of ears with unilateral COM and 17% of ears with bilateral COM demonstrated, respectively, seven and ten times that in controls. These statistically significant findings influence clinical considerations.
mesh_terms: D000158:Acoustic Impedance Tests; D000328:Adult; D000818:Animals; D001299:Audiometry; D001309:Auditory Threshold; D002682:Chinchilla; D003051:Cochlea / Q000503:physiopathology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D010033:Otitis Media / Q000150:complications*; D010035:Otitis Media, Suppurative / Q000150:complications* / Q000503:physiopathology; D011008:Pneumococcal Infections / Q000150:complications / Q000503:physiopathology