Natural DNP-binding immunoglobulins and antibody multispecificity.
Anti-DNP activity was found in normal human immunoglobulins with average affinities (10(4)-10(6) l/mole) and frequencies (15-2%) that correlate well with those expected from multispecific binding sites.
D000818:Animals; D000918:Antibody Specificity; D004136:Dinitrobenzenes / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D004912:Erythrocytes / Q000276:immunology; D006241:Haptens / Q000276:immunology; D006386:Hemagglutination Tests; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology*; D009578:Nitrobenzenes / Q000276:immunology*; D012756:Sheep / Q000276:immunology
D004136:Dinitrobenzenes; D006241:Haptens; D007136:Immunoglobulins; D009578:Nitrobenzenes