title: Sister Joseph's nodule: seven cases of umbilical metastases from gynecologic malignancies.
abstract: Seven cases of patients with gynecologic cancer and Sister Joseph's nodule, umbilical metastases from intraabdominal malignancy, are presented, making a total of 44 such cases in the literature. One such case, uterine leiomyosarcoma with umbilical metastases, is the first such lesion reported. Although the prognosis is generally poor, a few long-term survivors have been reported, and aggressive therapy may be warranted, particularly in patients with ovarian malignancy.
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms; D014472:Umbilicus; D014594:Uterine Neoplasms / Q000473:pathology