[Use of the human lymphoid Raji-line cell culture in tests of the toxicity of perfluorocarbon emulsions and their separate components].
The possibility has been shown of utilizing the culture of human lymphoid Raji cells as a highly sensitive object for toxicity testing of perfluorocarbon emulsions and their components. It has been disclosed that cytotoxicity of perfluorocarbon emulsions is primarily determined by its stabilizers--proxanoles. Theoretically, the cultures of animal cells are considered to be useful for toxicological studies.
D001802:Blood Substitutes / Q000633:toxicity; D002460:Cell Line; D002478:Cells, Cultured; D004655:Emulsions; D005466:Fluorocarbons / Q000633:toxicity*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects*; D010952:Plasma Substitutes / Q000633:toxicity; D011060:Poloxalene / Q000633:toxicity; D013329:Structure-Activity Relationship
D001802:Blood Substitutes; D004655:Emulsions; D005466:Fluorocarbons; D010952:Plasma Substitutes; D011060:Poloxalene
Ispol'zovanie kul'turi limfoidnykh kletok cheloveka linii Raji dlia testa na toksichnost' perftoruglerodnykh émul'siĭ i ikh otdel'nykh komponentov.