Therapeutic results using high-dose-rate intracavitary irradiation in cases of cervical cancer.
A comparison of the 5-year relative survival rates has been made between cases of cancer of the uterine cervix treated with 226Ra low-dose-rate intracavitary irradiation and those treated with 60Co high-dose-rate intracavitary irradiation (using the remote afterloading system, RALS). External irradiation using LINAC was also administered in both groups. The 5-year relative survival rates of the low-dose-rate cases were 82.6, 55.4, 49.0, and 18.2% in stage I, II, III, and IV cases, respectively, whereas they were 97.4, 55.1, 56.8, and 29.0% in the respective high-dose-rate cases. The differences between the two groups were not statistically significant. Delayed radiation complications of the rectum were frequent in both groups (approximately 14%) and those of the urinary bladder were somewhat less frequent (approximately 8%). The incidence of such complications did not differ significantly between the two groups.
D000328:Adult; D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004307:Dose-Response Relationship, Radiation; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011883:Radium / Q000627:therapeutic use; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*
D003037:Cobalt Radioisotopes; D011883:Radium