Purgative and anthelmintic effects of Mallotus philippinensis in rats against tape worm.
A resin isolated from Mallotus philippinensis (Kamala) caused a significant purgative effect after an oral dose (120 mg/kg) in rats as assessed from the weight of faeces as well as from the surface area of blotting paper soaked by liquid faeces. The anthelmintic effect of the resin was evaluated in albino rats found to be infested with tape worms. The resin in 60 and 120 mg/kg dose had a lethal effect on 35.69% and 78.21% population of tape worms respectively, in small intestine.
D000818:Animals; D000923:Anticestodal Agents; D002400:Cathartics; D007420:Intestine, Large / Q000469:parasitology; D007421:Intestine, Small / Q000469:parasitology; D008297:Male; D010270:Parasite Egg Count; D010946:Plants, Medicinal; D051381:Rats; D012376:Rodent Diseases / Q000188:drug therapy / Q000469:parasitology; D013622:Taeniasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary
D000923:Anticestodal Agents; D002400:Cathartics