title: The tissue pathologic features of metabolic bone disease.
abstract: In this article, an explanation and definition of basic terms used in metabolic bone disease are presented, with a review of histomorphometric findings in osteoporosis, osteomalacia, Paget's disease, and hyperparathyroidism. An appropriate bone biopsy protocol for diagnostic purposes is also presented.
mesh_terms: D001706:Biopsy / Q000379:methods; D001851:Bone Diseases, Metabolic / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D006801:Humans; D006961:Hyperparathyroidism / Q000473:pathology; D008856:Microscopy, Fluorescence; D008903:Minerals / Q000378:metabolism; D010001:Osteitis Deformans / Q000473:pathology; D010006:Osteoblasts / Q000473:pathology; D010010:Osteoclasts / Q000473:pathology; D010018:Osteomalacia / Q000473:pathology; D010024:Osteoporosis / Q000473:pathology; D013752:Tetracycline
chemical_list: D008903:Minerals; D013752:Tetracycline