title: [Arboviruses and lemurs in Madagascar: experimental infection of Lemur fulvus with attenuated strains of yellow fever virus].
abstract: Experimental infections of the malagasy Lemur fulvus have been carried out with two yellow fever virus attenuated strains (17D and FNV vaccine strains). A viremia is detected, with FNV virus only, between the 1rst and 11th day after inoculation. Haemagglutination inhibiting, complement fixing and neutralizing antibodies appear around the 10th day; the study of their dynamics shows their persistence through less than 6 months. These preliminary experiments are the first of a series of infections of malagasy lemurs by several Flaviviruses. The results might allow to evaluate the epidemiological role played by these prosimian primates in the arbovirus cycles in Madagascar.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D003168:Complement Fixation Tests; D005260:Female; D006385:Hemagglutination Inhibition Tests; D007900:Lemur; D007901:Lemuridae; D008270:Madagascar; D008297:Male; D009500:Neutralization Tests; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology; D015004:Yellow Fever / Q000276:immunology / Q000635:transmission; D015005:Yellow fever virus / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines
vernacular_title: Arbovirus et lémuriens à Madagascar: infection expérimentale de "Lemur fulvus" par des souches atténuées du virus amaril.