Effects of primaquine on serum biochemical and hematological parameters in anesthetized Macaca fascicularis.
Primaquine phosphate treatment (0.5 mg/kg/day, per os [p.o.], 14 days) significantly increased values for serum sodium, potassium, and uric acid, while calcium levels were decreased in male Macaca fascicularis. Serum values returned to baseline (pretreatment) levels by 30 days following primaquine treatment.
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002118:Calcium / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D004573:Electrolytes / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008251:Macaca / Q000097:blood*; D008252:Macaca fascicularis / Q000097:blood*; D008297:Male; D011188:Potassium / Q000097:blood; D011319:Primaquine / Q000494:pharmacology* / Q000633:toxicity; D012016:Reference Values; D012964:Sodium / Q000097:blood; D014527:Uric Acid / Q000097:blood*
D004573:Electrolytes; D014527:Uric Acid; D012964:Sodium; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D011319:Primaquine; D011188:Potassium; D002118:Calcium