title: A major human histone gene cluster on the long arm of chromosome 1.
abstract: A human histone gene cluster was assigned to chromosome 1 by Southern blot analysis of DNA's from a series of mouse-human somatic cell hybrids with 32P-labeled cloned human H4 and H3 histone DNA as probes. Localization of this histone gene cluster on the long arm of chromosome 1 was confirmed by in situ hybridization of this DNA probe to metaphase chromosomes.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D002906:Chromosomes, Human, 6-12 and X; D004247:DNA / Q000378:metabolism; D005796:Genes; D006657:Histones / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000378:metabolism; D051379:Mice; D009693:Nucleic Acid Hybridization
chemical_list: D006657:Histones; D004247:DNA