title: Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.
abstract: A statistical analysis of the distribution of charged residues in the N-terminal region of 39 prokaryotic and 134 eukaryotic signal sequences reveals a remarkable similarity between the two samples, both in terms of net charge and in terms of the position of charged residues within the N-terminal region, and suggests that the formyl group on Metf is not removed in prokaryotic signal sequences.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport; D002477:Cells / Q000378:metabolism*; D005057:Eukaryotic Cells / Q000378:metabolism*; D006801:Humans; D010455:Peptides / Q000032:analysis*; D011387:Prokaryotic Cells / Q000378:metabolism*; D021382:Protein Sorting Signals
chemical_list: D010455:Peptides; D021382:Protein Sorting Signals