Ultrastructural changes in mouse dermal capillaries induced by cytochalasin E.
Cytochalasin E increased the vascular permeability in the dermis of one-day-old mouse. It simultaneously induced edema and erythema as resulted from the leakage of plasma and red blood cells through the intercellular gaps of endothelial cells in both capillaries and venules. Meanwhile, there was a markedly decrease in plasma protein transport via pinocytotic vesicles.
D000818:Animals; D002196:Capillaries / Q000648:ultrastructure*; D002199:Capillary Permeability / Q000187:drug effects; D003572:Cytochalasins / Q000494:pharmacology*; D003594:Cytoplasmic Granules / Q000187:drug effects; D004848:Epithelium / Q000648:ultrastructure; D008297:Male; D008407:Mast Cells / Q000648:ultrastructure; D051379:Mice; D009183:Mycotoxins / Q000494:pharmacology*; D012039:Regional Blood Flow / Q000187:drug effects; D012867:Skin / Q000098:blood supply* / Q000648:ultrastructure; D013997:Time Factors
D003572:Cytochalasins; D009183:Mycotoxins; C007215:cytochalasin E