Interaction of fusogen substances with the erythrocyte membrane.
The influence of the fusogen substances poly-(ethylene glycol) (PEG) and linoleic acid on the dynamics and structure of the erythrocyte membrane was studied. Linoleic acid disturbs the lipid matrix and nonlamellar structures were formed. PEG affects the stability of membranes by changing the polarity of the aqueous medium and the hydration state of membrane lipids and proteins.
D002459:Cell Fusion / Q000187:drug effects; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism*; D005453:Fluorescence; D006801:Humans; D066298:In Vitro Techniques; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000494:pharmacology*; D008563:Membrane Lipids / Q000032:analysis; D011092:Polyethylene Glycols / Q000494:pharmacology*
D008041:Linoleic Acids; D008563:Membrane Lipids; D011092:Polyethylene Glycols; D019787:Linoleic Acid