title: Intraglomerular metastases. Report of two cases.
abstract: Glomerular metastases are rarely observed. Two cases of such metastases are reported. In one patient, proteinuria was detected and the diagnosis was made by kidney needle biopsy; light microscopy, immunofluorescence, and electron microscopy studies were performed. The second case was an autopsy finding. The histologic patterns were, respectively, an intracapillary metastasis and associated intra- and extracapillary metastases. These findings raise a number of questions concerning the early detection of such neoplastic diseases, the nature of primary tumors, and the mechanisms of malignant dissemination and glomerular localization.
mesh_terms: D001344:Autopsy; D001706:Biopsy; D002196:Capillaries / Q000473:pathology; D005260:Female; D006801:Humans; D007678:Kidney Glomerulus / Q000098:blood supply*; D007680:Kidney Neoplasms / Q000473:pathology / Q000556:secondary* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011379:Prognosis; D011507:Proteinuria / Q000473:pathology