[Mechanism of the modifying effect of neuraminidase of the influenza virus on the development of Rauscher leukemia].
It was established that neuraminidase--an immunosuppressive component of influenza virus--stimulated Rauscher leukemia in BALB/c mice. This effect is connected with earlier manifestation of sensitization to embryonic antigens and the appearance of immature PNL+ cells in spleens of infected mice rather than with immunosuppression. The mechanism of cocarcinogenic effect of viral neuraminidase is discussed.
D000372:Agglutination Tests; D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology; D000954:Antigens, Surface / Q000276:immunology; D003043:Cocarcinogenesis; D007114:Immunization; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009439:Neuraminidase / Q000494:pharmacology*; D009975:Orthomyxoviridae / Q000201:enzymology*; D011925:Rauscher Virus / Q000276:immunology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D009439:Neuraminidase
Mekhanizm modifitsiruiushchego vliianiia neraminidazy virusa grippa na razvitie leĭkoza Raushera.