The effects of unilateral ovariectomy during pregnancy on placental and fetal growth in mice.
A comparison between placental weight and number of fetuses in normal mice and those in mice unilaterally ovariectomized on the sixth day of pregnancy, revealed a relative hypertrophy of the placentae of the latter group, with a predominance of the effect in litter sizes of five or less. The weights of the fetuses in the unilaterally ovariectomized group were not significantly different from those of the controls, thus affording no evidence of a causal connection between fetal weight and gross placental weight.
D000818:Animals; D002369:Castration; D005314:Embryonic and Fetal Development; D005260:Female; D008433:Mathematics; D051379:Mice; D009929:Organ Size; D010053:Ovary / Q000502:physiology*; D010920:Placenta / Q000502:physiology*; D011247:Pregnancy; D011270:Pregnancy, Animal