Resistance of chickens immunized against Mycoplasma gallisepticum is mediated by bursal dependent lymphoid cells.
Newly hatched chickens were significantly protected against challenge by the virulent S6 strain of Mycoplasma gallisepticum after vaccination with the TS 100 mutant. Removal of the thymus did not abolish the protective effect of the vaccine, but removal of the bursa of Fabricius did. The results suggest that the resistance induced by vaccine is mediated by the bursal-dependent lymphoid cells.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001428:Bacterial Vaccines / Q000276:immunology*; D002060:Bursa of Fabricius / Q000166:cytology / Q000276:immunology*; D002645:Chickens / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000276:immunology / Q000662:veterinary*; D011201:Poultry Diseases / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology; D014611:Vaccination / Q000662:veterinary
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines