title: [Proliferation of precursor cells of the hemopoietic microenvironment in long-term mouse bone marrow cultures].
abstract: Active proliferation of stromal precursors was observed in long-term bone marrow cultures 2-11 days after seeding as measured by the hydroxyurea suicide method. In two-four-week-old cultures, the stromal precursors were mitotically dormant.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D001854:Bone Marrow Cells; D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D002478:Cells, Cultured; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D006918:Hydroxyurea / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008938:Mitosis / Q000187:drug effects / Q000528:radiation effects; D013997:Time Factors
chemical_list: D006918:Hydroxyurea
vernacular_title: Proliferatsiia kletok-predshestvennikov krovetvornogo mikrookruzheniia v dlitel'nykh kul'turakh kostnogo mozga mysheĭ.