Early cerebral prognosis of anoxic encephalopathy using brain energy metabolism.
Cerebral arteriovenous differences in oxygen content [C(a-v)O2] and glucose content [C(a-v)gluc] were used to predict outcome in 20 patients who remained comatose after resuscitation for cardiopulmonary arrest. Cerebral prognosis was good when C(a-v)O2 values were greater than 1.8 mMol/L and the oxygen glucose index (OGI) was greater than 85%. Our results suggest that cerebral recovery is linked with increased oxidation associated with the beginning of nonglycolytic metabolism.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose; D001921:Brain / Q000378:metabolism*; D004569:Electroencephalography; D005260:Female; D006323:Heart Arrest / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011379:Prognosis
D001786:Blood Glucose; D010100:Oxygen