Estrogen in the treatment of abnormal cervical mucus infertility.
The effects of intravaginal estrogen treatment on the cervical mucus and PCT were investigated in ten primarily infertile patients. The abnormal cervical mucus was the only demonstrable factor of their infertility. The duration of the infertility had ranged from 5-10 years. In four cases the percentual and progressive motilities of the spermatozoa improved and the number of spermatozoa rose in the PCT. Three of the patients conceived during the test cycle. In addition the effects of intramuscular estradiol-benzoate on the cervical mucus and PCT were investigated in clomiphene-treated patients. No differences were found between the test and the control cycle.
D000287:Administration, Topical; D000328:Adult; D002582:Cervix Mucus / Q000187:drug effects* / Q000502:physiology; D002996:Clomiphene / Q000008:administration & dosage; D004028:Dienestrol / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004958:Estradiol / Q000627:therapeutic use; D004967:Estrogens / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000503:physiopathology; D007273:Injections, Intramuscular; D008597:Menstrual Cycle
D004967:Estrogens; D002996:Clomiphene; D004958:Estradiol; D004028:Dienestrol