Morphological changes of the isocortex in morbus Parkinson.
An increasing number of pyramidal cells in the third layer of the human neocortex with pigment-filled expansions of their proximal axon is correlated with advancing age. Comparison between cases of morbus Parkinson and an age-matched control group reveals that the number of these pathologically altered pyramidal cells is significantly higher in cases of morbus Parkinson than in controls.
D000368:Aged; D000375:Aging; D001369:Axons / Q000378:metabolism; D002540:Cerebral Cortex / Q000166:cytology / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000378:metabolism / Q000473:pathology*; D010860:Pigments, Biological / Q000378:metabolism*
D010860:Pigments, Biological