DNA synthesis in Pseudomonas acidovorans infected with mutants of bacteriophage phi W-14 defective in the synthesis of alpha-putrescinylthymine.
Normal levels of the hypermodified pyrimidine, alpha-putrescinylthymine, which is formed from hydhydroxymethyluracil at the polynucleotide level (Maltman et al., J. Virol. 34:354-359, 1984), are not required in bacteriophage luminal diameterW-14 DNA for the DNA to serve as a replicative template in luminal diameterW-14-infected cells.
D001435:Bacteriophages / Q000235:genetics*; D004261:DNA Replication; D004279:DNA, Viral / Q000096:biosynthesis*; D009154:Mutation; D011549:Pseudomonas / Q000235:genetics*; D013941:Thymine / Q000031:analogs & derivatives* / Q000096:biosynthesis; D014779:Virus Replication
D004279:DNA, Viral; C025113:alpha-putrescinylthymine; D013941:Thymine