Vitrectomy and intravitreal antiviral drug therapy in acute retinal necrosis syndrome. Report of two cases.
Two patients with acute retinal necrosis were treated with vitrectomy, intravitreal infusion of acyclovir, and prophylactic scleral buckling procedures. Both patients have had a uneventful postoperative course and a recovery of visual acuity; follow-up has been at five and 14 months. There has been no sign of toxicity from the intravitreally administered acyclovir by electroretinographic or clinical criteria.
D000208:Acute Disease; D000212:Acyclovir / Q000008:administration & dosage*; D000293:Adolescent; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000628:therapy*; D012591:Scleral Buckling; D013577:Syndrome; D014821:Vitrectomy; D014822:Vitreous Body
D000212:Acyclovir