[The effect of cystamine on the survival of mice and endogenous colony-formation in combined radiation-thermal injuries].
In experiments on mice it was shown that cystamine exerts its protective action not only against the concurrent effect of ionizing radiation and weak thermal injury but also against the effect of heat (burn) 48 h after irradiation with a midlethal dose (30-day-death decreased from 95 to 20%).
D000818:Animals; D002056:Burns / Q000150:complications / Q000401:mortality* / Q000473:pathology; D003114:Colony-Forming Units Assay; D003538:Cystamine / Q000494:pharmacology* / Q000627:therapeutic use; D006412:Hematopoietic Stem Cells / Q000187:drug effects* / Q000473:pathology / Q000528:radiation effects; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000150:complications / Q000401:mortality* / Q000473:pathology / Q000517:prevention & control; D011836:Radiation Tolerance
D003538:Cystamine
Vliianie tsistamina na vyzhivaemost' mysheĭ i éndogennoe kolonieobrazovanie pri kombinirovannykh radiatsionno-termicheskikh porazheniiakh.