[Effect of etimizol on age-related characteristics of the formation of the conditioned passive avoidance reaction].
The authors have demonstrated the effect of ethimizol on the processes of training and consolidation, the duration of memory traces, and process of reproduction in adult and old mice and rats. It has been found that ethimizol in doses of 1.5-5 mg/kg facilitates the formation of passive avoidance behavior in old animals difficult to be trained and raises the duration of storing the reflex formed in both the age groups. The improvement of reproduction of passive avoidance behavior after ethimizol administration has been discovered to be characteristic for old animals.
D000375:Aging / Q000187:drug effects*; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D003214:Conditioning, Classical / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005042:Etimizol / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D008568:Memory / Q000187:drug effects; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains; D012054:Reinforcement, Psychology; D013997:Time Factors
D007093:Imidazoles; D005042:Etimizol
Vliianie étimizola na vozrastnye osobennosti formirovaniia uslovnoĭ reaktsii passivnogo izbeganiia.