title: Ventricular size in patients with presenile dementia of the Alzheimer's type.
abstract: The computed tomograms (CTs) of eight mild to moderately impaired patients with presenile dementia of Alzheimer's type (aged 53 to 64 years) were compared with scans of ten healthy age-matched controls. Two computer programs and a variety of linear measurements were used to analyze the CTs. A single computerized measure of fluid volume on the slice at the maximum width of the bodies of the lateral ventricles correctly predicts the group membership of 88.89% of the subjects. Computerized measures on other CT slices do not increase discrimination between the groups. Easily performed linear measures correctly predict the group membership of 78.9% of the subjects. Computerized measures of ventricular size may provide highly valuable information for the diagnosis of Alzheimer's disease in the presenile age range.
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000000981:diagnostic imaging* / Q000473:pathology / Q000523:psychology; D002552:Cerebral Ventricles / Q000033:anatomy & histology; D003704:Dementia / Q000000981:diagnostic imaging* / Q000473:pathology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests; D014057:Tomography, X-Ray Computed