[Experimental study of the need for the dearterialization of tumors].
The influence of local ischaemia on the tumor growth rate and the character of metastases of Walker's carcinosarcoma-256 (WCS-256) and carcinoma RS-1 was studied in 168 male rats of Wistar line. The authors observed the dependence between the quantity of tumour cells in peripheral blood both under normal conditions and under local ischaemia in the tumour area. The efficiency of the produced ischaemia was controlled by the polarographic methods. The local ischaemia decreases grafting of tumours, reduces the growth rate and formation of the regional and distant metastases and decreases the quantity of the tumour cells in the peripheral blood.
D000818:Animals; D001158:Arteries; D002279:Carcinoma 256, Walker / Q000098:blood supply / Q000378:metabolism / Q000473:pathology; D002455:Cell Division; D007511:Ischemia / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009374:Neoplasms, Experimental / Q000098:blood supply* / Q000378:metabolism / Q000473:pathology; D009360:Neoplastic Cells, Circulating; D010101:Oxygen Consumption; D010313:Partial Pressure; D051381:Rats; D011919:Rats, Inbred Strains
Eksperimental'noe obosnovanie tselesoobraznosti primeneniia dezarterializatsii opukholeĭ.