title: [The blood-testis barrier].
abstract: The blood-testis barrier in man is mainly due to the tight junctions of Sertoli cells. It creates favorable conditions for the spermatogenesis and sperm survival in the testicular fluid. It prevents the occurrence of autoimmunity after puberty. The alteration of the blood-testis barrier allows the production of antisperm antibodies and may lead to infertility.
mesh_terms: D000917:Antibody Formation; D001814:Blood-Testis Barrier; D006801:Humans; D008297:Male; D012708:Sertoli Cells / Q000502:physiology; D013091:Spermatogenesis; D013094:Spermatozoa / Q000276:immunology / Q000378:metabolism; D013737:Testis / Q000502:physiology
vernacular_title: La barriére hémato-testiculaire.