A case of blastomycosis from Zaria, Nigeria.
A case of blastomycosis from Zaria, Nigeria is reported. The clinical features were indistinguishable from those of tuberculosis which is very common in this environment. Lack of response to anti-tuberculosis therapy within eight weeks prompted the search for other organisms which resulted in the isolation of Blastomyces dermatitidis. Compatible histological evidence was obtained. Subsequent favourable response to amphotericin B was evident. Infection with this organism should be included in the differential diagnosis of pulmonary and pleural lesions simulating tuberculosis in West Africa.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001758:Blastomyces / Q000302:isolation & purification; D001759:Blastomycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D010996:Pleural Effusion / Q000382:microbiology; D013183:Sputum / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis
D000666:Amphotericin B