A serum mannan-binding protein and candidiasis.
A mannan-binding protein purified from rabbit serum agglutinated Saccharomyces cerevisiae in a Ca2+-dependent manner. Its binding to related carbohydrate ligands is reduced either by yeast mannan at 10 ng ml-1 or serum from patients with suspected deep-seated candidiasis. A role for mannan-binding protein in diagnosis and pathogenesis is considered.
D000818:Animals; D002177:Candidiasis / Q000175:diagnosis / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D037222:Collectins; D006735:Horseradish Peroxidase / Q000378:metabolism; D006801:Humans; D008351:Mannans / Q000378:metabolism; D011817:Rabbits
D002352:Carrier Proteins; D037222:Collectins; D008351:Mannans; D006735:Horseradish Peroxidase