title: [Clinical experiment studies in the treatment of echinococcosis with mebendazole (Vermox)].
abstract: 3 patients with echinococcosis were treated with Mebendazol conservatively. One patient got a drug allergy. The other two were operated after a conservative therapy during 3 years in one case and in the course of 110 days in the other case. Dead as well as vital echinococcus cysts and protobrood-cysts were found intraoperatively. The intraabdominal transmission of protobrood-cysts to white infantile mice led to a secondary echinococcosis. The surgical therapy appeared more efficacious in contrast to the conservative treatment. A combination of surgical therapy and conservative treatment is to be recommended in severe disseminated forms of the echinococcosis.
mesh_terms: D000328:Adult; D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004443:Echinococcosis / Q000188:drug therapy* / Q000601:surgery; D004444:Echinococcosis, Hepatic / Q000188:drug therapy / Q000601:surgery; D004446:Echinococcus / Q000472:pathogenicity; D006801:Humans; D008463:Mebendazole / Q000627:therapeutic use*; D051379:Mice; D008815:Mice, Inbred Strains; D008875:Middle Aged
chemical_list: D001562:Benzimidazoles; D008463:Mebendazole
vernacular_title: Klinisch-experimentelle Untersuchungen bei der Behandlung der Echinokokkose mit Mebendazol (Vermox).