Ca2+ uptake of sarcoplasmic reticulum in experimental glucocorticosteroid myopathy.
The effect of twenty-one days dexamethasone treatment was investigated on the Ca2+ uptake of sarcoplasmic reticulum (SR) of slow-twitch (soleus) and fast-twitch (semi-membranosus) muscles. The SR Ca2+ uptake decreased in fast-twitch muscle significantly, while in slow-twitch muscle there was no detectable change.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003907:Dexamethasone; D005260:Female; D008297:Male; D009135:Muscular Diseases / Q000139:chemically induced / Q000378:metabolism*; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*
D003907:Dexamethasone; D002118:Calcium