title: Cerebellar ataxia due to procainamide toxicity.
abstract: It has become appreciated that drug levels of procainamide hydrochloride needed to suppress inducible ventricular tachycardia by programmed ventricular stimulation exceed the previously published therapeutic range. Cerebellar ataxia developed acutely in a patient receiving high-dose procainamide. This was associated with a marked increase in the serum drug level. Resolution occurred within three days after drug therapy was discontinued.
mesh_terms: D000284:Administration, Oral; D002524:Cerebellar Ataxia / Q000139:chemically induced*; D004334:Drug Administration Schedule; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D008875:Middle Aged; D011342:Procainamide / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood; D013610:Tachycardia / Q000188:drug therapy
chemical_list: D011342:Procainamide