title: [Age and sex dependence of tubular kidney clearance in childhood].
abstract: Nuclear medicine methods have gained wide-spread use for quantitative determination of renal function, but normal values related to age and sex are often not available, especially in children. Since pediatric clearance studies in our clinic are carried out routinely by means of I-123-OIH (ortho-iodo-hippurate), OIH-clearance determinations were performed in 33 children considered to have normal renal function. Within the investigated age of 3,5-15 years no significant correlation of tubular renal clearance with age and no difference between both sexes was found, the mean value +/- SD being 577 +/- 88 ml/min/1,73 m2 surface area. Comparing all age related values known from literature, our values from children and adults fit in quite well.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007465:Iodohippuric Acid; D007677:Kidney Function Tests / Q000379:methods*; D007684:Kidney Tubules / Q000000981:diagnostic imaging*; D008297:Male; D008657:Metabolic Clearance Rate; D011877:Radionuclide Imaging; D012016:Reference Values; D012737:Sex Factors
chemical_list: D007465:Iodohippuric Acid
vernacular_title: Alters- und Geschlechtsabhängigkeit der tubulären Nierenclearance im Kindesalter.