title: [Effect of ionic strength of the medium on the structure and aggregation of histone H1 from the calf thymus].
abstract: In the region of 50 mM NaCl histone HI has the structure with a great number of binding sites with fluorescent probe 1.8-ANS as compared to the structure formed in solution of 0.6-1.0 M NaCl. These sites, however, have a lower constant of binding with the probe and are characterized by a higher surrounding polarity. At local significant increase of the ionic strength histone HI molecules form stable oligomers having hydrophobic cavities. A conclusion is made about the importance of cationic envelope formed by N- and C-ends around the globular "head", for manifesting effective interactions between several molecules of histone HI.
mesh_terms: D000817:Anilino Naphthalenesulfonates; D000818:Animals; D002417:Cattle; D005456:Fluorescent Dyes; D006657:Histones; D009994:Osmolar Concentration; D011487:Protein Conformation; D013050:Spectrometry, Fluorescence; D013950:Thymus Gland
chemical_list: D000817:Anilino Naphthalenesulfonates; D005456:Fluorescent Dyes; D006657:Histones; C027132:1-anilino-8-naphthalenesulfonate
vernacular_title: Vliianie ionnoĭ sily sredy na strukturu i agregatsiiu gistona H1 iz timusa telenka.