Natural-killer-cell activity in atopic dermatitis.
Natural-killer (NK)-cell activity was measured in the peripheral blood of twenty patients with atopic dermatitis and in a group of thirteen age-matched non-atopic controls (nine subjects on thirteen occasions). The method uses a chromium-release assay with the human leukaemia cell line, K562, labelled with 51Cr as the target cell. A highly significant reduction in NK-cell activity was found in the patients with atopic dermatitis.
D000293:Adolescent; D000328:Adult; D003601:Cytotoxicity Tests, Immunologic; D003876:Dermatitis, Atopic / Q000276:immunology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D008875:Middle Aged