title: A stathmokinetic study on the ruminal epithelium of sheep.
abstract: The metaphase arresting method using colchicine was applied to a kinetic study of the proliferation of sheep ruminal epithelium. Mitotic rate, calculated from the regression coefficient of the metaphase accumulation, was 0.0025 mitoses/cell per hour. Assuming the cell cycle time is about 24 hours as reported by Goodlad (1981), the growth fraction was calculated to be about 9%. The validity of the stathmokinetic method for ruminal cell kinetics is discussed.
mesh_terms: D000818:Animals; D003078:Colchicine / Q000494:pharmacology; D004847:Epithelial Cells; D007700:Kinetics; D008938:Mitosis / Q000187:drug effects; D012417:Rumen / Q000166:cytology* / Q000378:metabolism; D012756:Sheep / Q000166:cytology* / Q000378:metabolism
chemical_list: D003078:Colchicine