title: [Chronic noncalculous cholecystitis with refractory relapsing course (clinico-laboratory correlates)].
abstract: The immunological (lymphocyte blast transformation with PHA, determination of IgA, IgM, IgG), cytochemical (the mean cytochemical index of neutrophil lipids, glycogen, peroxidase content), hematological (the leukocyte, lymphocyte and neutrophil counts), and biochemical tests were employed to study immune responsiveness in 108 patients with chronic non-calculous cholecystitis running a refractory relapsing course. The patients showed the signs of immune deficiency. Some of the above described tests turned out informative for detecting such deficiency. It has been demonstrated that conventional therapy does not provide any stable clinical effect, aggravating the manifestations of immune deficiency. The introduction into the complex of treatment measures of diphenhydramine, saparal and levamisole, in particular, favoured more rapid elimination of the clinical symptoms of a relapse, of allergic reactions, psychoemotional disorders and reduced the signs of a decrease in immune responsiveness in patients with chronic non calculous cholecystitis running a refractory relapsing course.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002756:Cholagogues and Choleretics / Q000627:therapeutic use; D002764:Cholecystitis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D002908:Chronic Disease; D004155:Diphenhydramine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D017099:IgG Deficiency; D007978:Levamisole / Q000627:therapeutic use; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D002756:Cholagogues and Choleretics; D007978:Levamisole; D004155:Diphenhydramine
vernacular_title: Khronicheskiĭ beskamennyĭ kholetsistit s upornym retsidiviruiushchim techeniem (kliniko-laboratornye paralleli).