Complete heart block following a single dose of trazodone.
Forty minutes after receiving a single starting dose of trazodone, a patient developed complete heart block. The case illustrates that, despite the results of earlier studies, trazodone's effect on cardiac conduction may be severe in individuals at risk for conduction delay.
D000368:Aged; D003866:Depressive Disorder / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D006327:Heart Block / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010879:Piperazines / Q000009:adverse effects*; D013997:Time Factors; D014196:Trazodone / Q000009:adverse effects*
D010879:Piperazines; D014196:Trazodone