title: Effects of extracellular calcium and magnesium on junctional intercellular communication in human fibroblasts.
abstract: The role of extracellular calcium and magnesium in intercellular communication via permeable junctions was studied by measuring metabolic co-operation between ASS- and ASL- human fibroblasts. Communication through pre-existing junctions was not affected by the removal of extracellular calcium and magnesium from the medium. On the other hand, the establishment of communication through new permeable junctions, when ASS- and ASL- cells were mixed, was dependent on the presence of extracellular calcium and magnesium.
mesh_terms: D002118:Calcium / Q000494:pharmacology*; D002450:Cell Communication / Q000187:drug effects*; D002460:Cell Line; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D007365:Intercellular Junctions / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology*; D012867:Skin / Q000166:cytology
chemical_list: D008274:Magnesium; D002118:Calcium