Changes of bone marrow cell and peripheral blood cell counts in newborn mice.
Differential bone marrow cell and peripheral blood cell counts in new-born mice from zero to twenty-one days of age were investigated. In the bone marrow, erythroblasts rapidly increased whereas granulocytic cells decreased with time. The G/E ratio was 6.7 on day zero and 0.5 on day four, and as the G/E ratio of adult mice is normally from 0.8 to 2.4, these values would be the highest and lowest respectively for the whole life span of a mouse. In the peripheral blood, MCV decreased each day, closely matching the changes in the Price-Jones curves. The results of erythrocyte area measurements indicate that the larger the erythrocyte area, the earlier in days of age it disappeared and the shorter its life span.
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology* / Q000097:blood; D001772:Blood Cell Count / Q000662:veterinary; D001854:Bone Marrow Cells; D002452:Cell Count; D051379:Mice; D008815:Mice, Inbred Strains / Q000033:anatomy & histology* / Q000097:blood