Intracranial hemorrhage and vitamin K deficiency in early infancy.
We report late-onset (1/2 to 6 months of age) intracranial hemorrhage related to vitamin K deficiency in 32 breast-fed infants, 31 of whom received no prophylactic vitamin K at birth. Computerized tomography showed mild to severe intracranial hemorrhage. Most (90.6%) had subarachnoid hemorrhage, either alone or in combination with subdural hemorrhage (37.5%), parenchymal hemorrhage (31.3%), or intraventricular hemorrhage (12.5%). In three (9.4%) the infratentorial region was involved.
D001942:Breast Feeding; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006408:Hematoma, Subdural / Q000209:etiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013345:Subarachnoid Hemorrhage / Q000209:etiology; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014813:Vitamin K Deficiency / Q000150:complications*