[A case of AIDS in a hemophilia B patient in France].
AIDS is reported in a 14 year old hemophiliac B. This patient was treated on demand and used 800 F IX IU per kg B.W. and per year. He presented with severe opportunistic infection (Toxoplasmosis) and profound impairment of cellular immunity. He suffered of chronic active hepatitis and he was chronic HBs Ag carrier. A retrovirus (LAV) was isolated from his cultured T lymphocytes. He had no other identified risk factor than severe hemophilia B. The occurrence of AIDS in hemophiliacs suggests a relationship between the transfusion of blood products and the disease. The cause of AIDS is unknown. A possible relationship between LAV and AIDS is discussed.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000209:etiology / Q000382:microbiology; D000293:Adolescent; D005164:Factor IX / Q000627:therapeutic use; D002836:Hemophilia B / Q000150:complications*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006521:Hepatitis, Chronic / Q000150:complications; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D012190:Retroviridae / Q000032:analysis; D065227:Transfusion Reaction
D006514:Hepatitis B Surface Antigens; D005164:Factor IX
Un cas de SIDA chez un hémophile B en France.