title: [Chemotherapy of carcinoma of the upper respiratory and digestive tract].
abstract: New regimens of chemotherapy in previously untreated squamous cell head and neck carcinoma yielded a 60 per cent rate of regression in over 50 per cent of patients. Planned radical surgery may be delayed and curative irradiation is often preferred. However, many patients have been excluded for polychemotherapy because of poor general condition. The results of simultaneous perioperative chemotherapy and X-ray therapy are not well known. Adjuvant chemotherapy after initial treatment is difficult to apply and to appreciate for results. Chemotherapy of recurrences is disappointing, even if efficient. Randomised trials are necessary to improve our knowledge in this field.
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D004067:Digestive System Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010039:Otorhinolaryngologic Neoplasms / Q000188:drug therapy*; D012142:Respiratory Tract Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Chimiothérapie des carcinomes des voies aéro-digestives supérieures.