[Study of energy characteristics of 5-fluorouracil analogs by photoionization mass-spectrometry].
The fragmentation pathways of N-1-alkoxyalkyl derivatives of 5-fluorouracil and various analogues of an antitumor drug ftorafur have been examined using a mass-spectrometry technique. The ionization and appearance energies for major ions of the compounds under study have been determined on the basis of the ionization efficiency curves obtained using photoionization mass-spectrometry. Different transport forms of 5-fluorouracil have been demonstrated to be similar in the stability of their pseudoglycosidic C-N bond.
D055598:Chemical Phenomena; D002621:Chemistry; D005472:Fluorouracil / Q000031:analogs & derivatives*; D013058:Mass Spectrometry / Q000379:methods; D013329:Structure-Activity Relationship
D005472:Fluorouracil
Izuchenie énergeticheskikh kharakteristik proizvodnykh 5-ftoruratsila metodom fotoionizatsionnoĭ mass=spektrometrii.