[Changes in the indices of lipid peroxidation in liver mitochondria of white rats during simulation of in vitro anoxic damage].
Lipid peroxidation was studied in the course of the development of anoxic injury to the mitochondria in vitro. Hydrolysis of mitochondial phospholipids was accompanied by an increase in antioxidant activity (AOA) of the organelles. At the same time the ability to transoxidation in liposomes formed from lipids extracted from the injured mitochondria was discovered to be increased. It is assumed that AOA of the mitochondria rises at the expense of antioxidants not extractable with a mixture of chloroform and methanol.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003300:Copper / Q000494:pharmacology; D000860:Hypoxia / Q000378:metabolism*; D007501:Iron / Q000494:pharmacology; D008054:Lipid Peroxides / Q000378:metabolism*; D008081:Liposomes / Q000378:metabolism; D008163:Luminescent Measurements; D008345:Manganese / Q000494:pharmacology; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects; D051381:Rats
D008054:Lipid Peroxides; D008081:Liposomes; D008345:Manganese; D003300:Copper; D007501:Iron; D002118:Calcium
Izmeneniia nekotorykh pokazateleĭ perekisnogo okisleniia lipidov mitokhonriĭ pecheni belykh krys pri modelirovanii ikh anoksicheskogo povrezhdeniia in vitro.