Reduced locomotor activity as an acute effect of damage to superior colliculus in rats.
Rats with either electrolytic or radiofrequency lesions of the superior colliculus were tested in an open-field within 24 h of operation. They crossed significantly fewer squares and spent more time motionless then control animals, an effect that disappeared upon retesting 13 days later. Previously reported locomotor hyperactivity thus appears to be a chronic but not an acute effect of collicular damage in rats.
D000818:Animals; D001931:Brain Mapping; D008297:Male; D008636:Mesencephalon / Q000502:physiology; D009043:Motor Activity / Q000502:physiology*; D051381:Rats; D012154:Reticular Formation / Q000502:physiology; D013477:Superior Colliculi / Q000502:physiology*