title: [Physiopathology and therapy of severe cerebral hypoxia].
abstract: The pathophysiological mechanisms of severe cerebral hypoxia (in men) are discussed: disturbance of autoregulation, vasoparalysis, luxury perfusion, cytotoxic and vasogenic brain swelling, rise of intracranial pressure (ICP), stop of cerebral circulation. Possible trials of therapy are presented: restitution of cardiovascular circulation, controlled hyperventilation, control of ICP, dexamethason bolus, early high-dose barbiturates.
mesh_terms: D001929:Brain Edema / Q000503:physiopathology; D002545:Brain Ischemia / Q000503:physiopathology; D002536:Cerebral Arteries / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects; D002648:Child; D003131:Combined Modality Therapy; D006706:Homeostasis; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology* / Q000628:therapy; D007427:Intracranial Pressure / Q000187:drug effects
vernacular_title: Pathophysiologie und Therapie der schweren zerebralen Hypoxie.