A study of transacetylation between 3,6-diacetylmorphine and morphine.
Interaction between some of the constituents of illicitly prepared heroin results in the formation of 6-acetylmorphine. Such interactions have been observed during the gas chromatographic examination of heroin. An explanation of these reactions is proposed. Attempts to block the formation of 6-acetylmorphine were not successful, although the problem is minimised by using the lowest temperature consistent with satisfactory chromatography.
D000107:Acetylation; D001205:Ascorbic Acid / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004340:Drug Contamination; D003932:Heroin / Q000032:analysis*; D013287:Illicit Drugs; D009020:Morphine / Q000032:analysis*
D013287:Illicit Drugs; D003932:Heroin; D009020:Morphine; D001205:Ascorbic Acid