title: [Protective medium for the lyophilization of a live vaccine against swine erysipelas--VR2].
abstract: Hydrolysate was obtained through enzyme hydrolysis from waste residual fibrin in the production of hyperimmune swine blood. Fibrin hydrolysate and gelatose in 2.5 : 1.5 ratio were tested as protective medium for the freeze-drying of VR2 vaccine against swine erysipelas. It was found that the freeze-drying of the vaccine with the addition of the hydrolysate-gelatose medium at the rate of 4-5 per cent of the vaccine volume met the requirements of the standard for sterility, innocuity, vaccinal titer, and residual moisture.
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines / Q000302:isolation & purification*; D003470:Culture Media / Q000494:pharmacology*; D004888:Erysipelothrix / Q000276:immunology*; D004889:Erysipelothrix Infections / Q000517:prevention & control*; D005337:Fibrin / Q000494:pharmacology; D005612:Freeze Drying / Q000379:methods; D011492:Protein Hydrolysates / Q000494:pharmacology; D013552:Swine; D013554:Swine Erysipelas / Q000517:prevention & control*
chemical_list: D001428:Bacterial Vaccines; D003470:Culture Media; D011492:Protein Hydrolysates; D005337:Fibrin
vernacular_title: Zashtitna sreda za liofilizirane na zhiva vaksina protiv chervenka po svinete--VR2.