Familial centric fission of chromosome 4.
A centric fission of chromosome 4 is described in the proband and his mother, both phenotypically normal. In addition, partial monosomy for the long arm or the short arm or both of chromosome 4 may have been present in two of the proband's sibs who died in infancy and childhood, respectively.
D002503:Centromere / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002905:Chromosomes, Human, 4-5; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree