[Effect of posttraumatic fluctuations in the oxygen tension value in the arterial blood on the intensity of lipid peroxidation in the lungs, liver and myocardium of rats with a lung contusion].
It has been demonstrated in rat experiments that accumulation of lipid peroxidation products in the lungs, liver and myocardium in the early posttraumatic period of pulmonary contusion (the first week after trauma) is observed during the recovery of oxygen tension is the arterial blood (PaO2) rather than during the period of the appearance of arterial hypoxemia. In the lungs, accumulation of malonic dialdehyde (MDA) occurred together with PaO2 recovery in the myocardium and liver, MDA was recorded to accumulate in the initial period of PaO2 recovery, whereupon the MDA content in the myocardium dropped to the MDA content in the myocardium of intact rats, while that in the liver returned to normal only partially.
D000818:Animals; D001158:Arteries; D003288:Contusions / Q000378:metabolism*; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D055370:Lung Injury; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D010313:Partial Pressure; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014949:Wounds, Nonpenetrating / Q000378:metabolism
D008054:Lipid Peroxides; D010100:Oxygen
Vliianie posttravmaticheskikh kolebaniĭ velichiny napriazheniia kisloroda v arterial'noĭ krovi na intensivnost' perekisnogo okisleniia lipidov legkikh, pecheni i miokarda u krys s kontuzieĭ legkikh.