Anion exchange in human erythrocytes has a large activation volume.
Sulfate equilibrium exchange in human red cells has an activation volume of +150 +/- 20 cm3/mol over the pressure range 0.1 to 83 MPa (15 to 12000 lb/in2) at 30 degrees C. This value greatly exceeds the expected contribution from sulfate binding to the anion exchanger. We suggest that the activation volume reflects conformational changes during the transport cycle.
D027321:Anion Transport Proteins; D001692:Biological Transport; D002352:Carrier Proteins / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D008433:Mathematics; D013431:Sulfates / Q000097:blood
D027321:Anion Transport Proteins; D002352:Carrier Proteins; D013431:Sulfates