Double blind study of the toxicity of intrathecal iopamidol and metrizamide in lumbar myelography.
Water-soluble contrast agents (metrizamide) provide a finer myelographic assessment of the spinal neuroanatomical structures but at the expense of some occasional toxic side effects. Iopamidol, a new non-ionic water-soluble agent, has been submitted to clinical trial by the authors in their respective institutions. The combined results indicate better tolerance to this new agent with fewer side effects and those of lesser severity.
D004244:Dizziness / Q000139:chemically induced; D004311:Double-Blind Method; D006261:Headache / Q000139:chemically induced; D006801:Humans; D007479:Iopamidol; D007483:Iothalamic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D008793:Metrizamide / Q000009:adverse effects*; D009192:Myelography; D009325:Nausea / Q000139:chemically induced
D007483:Iothalamic Acid; D007479:Iopamidol; D008793:Metrizamide