X-ray-induced translocations in marmoset (Callithrix jacchus) stem-cell spermatogonia.
The induction of reciprocal translocations in spermatogonial stem cells of marmosets (Callithrix jacchus) was studied after irradiation with different doses of X-rays (50, 100 and 200 rad) via spermatocyte analysis many cell generations later. The obtained results show a dose-effect relationship with clear saturation effects at 200 rad. The recorded frequencies of translocations were much lower than those reported for closely related marmosets (Saguinus fuscicollis and Saguinus oepidus). Possible reasons for this difference are discussed.
D000818:Animals; D002144:Callithrix; D008297:Male; D011833:Radiation Injuries, Experimental / Q000235:genetics / Q000473:pathology*; D013091:Spermatogenesis / Q000528:radiation effects*; D013093:Spermatogonia / Q000528:radiation effects*; D013094:Spermatozoa / Q000528:radiation effects*; D013737:Testis / Q000528:radiation effects; D014178:Translocation, Genetic / Q000528:radiation effects*; D014965:X-Rays