title: CL 259,971: a potent new polyether anticoccidial. 2. Floor-pen trials.
abstract: Three floor-pen trials have confirmed the high anticoccidial activity of CL 259,971 as first reported in batteries. The optimal dosage level was shown to be 5 ppm in the diet. At this level, excellent anticoccidial activity was observed with no adverse effect on weight or performance. The results indicated that 5 ppm of CL 259,971 provided efficacy and performance comparable to arprinocid or monensin, which were used for comparison in these trials.
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology; D000821:Animal Feed; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D003048:Coccidiosis / Q000188:drug therapy / Q000401:mortality / Q000662:veterinary*; D003049:Coccidiostats / Q000494:pharmacology / Q000627:therapeutic use*; D004734:Energy Metabolism / Q000187:drug effects; D004987:Ethers / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005503:Food Additives; D008297:Male; D008985:Monensin / Q000494:pharmacology; D011201:Poultry Diseases / Q000188:drug therapy* / Q000401:mortality
chemical_list: D003049:Coccidiostats; D004987:Ethers; D005503:Food Additives; C016245:arprinocid; D008985:Monensin; C042188:CL 259971; D000225:Adenine