Monoclonal gammopathy and mycosis fungoides. Report of four cases and review of the literature.
Of four patients with mycosis fungoides and monoclonal gammopathy, one died of multiple myeloma that developed 4 years after the mycosis fungoides. The other three had monoclonal gammopathy of undetermined significance. This association does not appear to occur with a high frequency in patients with mycosis fungoides than in the general population. However, it demonstrates that B cell proliferation can occur in patients with primary cutaneous T cell disease.
D000368:Aged; D000911:Antibodies, Monoclonal / Q000032:analysis; D004406:Dysgammaglobulinemia / Q000150:complications / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000276:immunology*; D009182:Mycosis Fungoides / Q000150:complications / Q000276:immunology*; D012878:Skin Neoplasms / Q000150:complications / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G