[New informative index of the functional status of polymorphonuclear neutrophils].
A new test was applied to study the function of polymorphonuclear neutrophils according to their ability to form oreols in a hypertonic medium. During inhibition of neutrophil function in vivo (desympathetization, tumor growth), oreol formation increased. Stimulation of neutrophils in vitro by adding noradrenaline to the incubation medium led to a decrease in their oreol-forming ability. The data obtained enabled the authors to offer the test for detecting the functional activity of polynuclear cells.
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D004837:Epinephrine / Q000494:pharmacology; D006145:Guanethidine; D006982:Hypertonic Solutions; D008722:Methods; D008748:Methylcholanthrene; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D012513:Sarcoma, Experimental / Q000097:blood / Q000139:chemically induced; D013499:Surface Properties; D013563:Sympathectomy, Chemical
D006982:Hypertonic Solutions; D008748:Methylcholanthrene; D004837:Epinephrine; D006145:Guanethidine
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