Plasma oncomodulin is proportional to tumour burden in rats bearing Morris hepatomas 5123D, 5123tc, 7288 and 7777.
The small acidic calcium-binding protein, oncomodulin, was detected by radioimmunoassay in the plasma of rats bearing Morris hepatomas 5123D, 5123tc, 7288ctc, and 7777. The concentration of plasma oncomodulin was proportional to the tumour burden. When the tumour was surgically removed, the plasma oncomodulin level dropped to undetectable levels. No oncomodulin was detected in the circulation of normal rats.
D000818:Animals; D002135:Calcium-Binding Proteins / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D008114:Liver Neoplasms, Experimental / Q000097:blood*; D009363:Neoplasm Proteins / Q000097:blood*; D011863:Radioimmunoassay; D051381:Rats
D002135:Calcium-Binding Proteins; D009363:Neoplasm Proteins; C034733:oncomodulin