Probable adverse interaction between oral metoprolol and verapamil.
A combination of an oral beta-adrenergic blocking agent and verapamil has been advocated as a safe treatment for angina. A case of Wenckebach type atrioventricular block occurring in a patient on metoprolol and verapamil is reported. It is suggested that this combination is used with caution.
D000787:Angina Pectoris / Q000188:drug therapy; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006327:Heart Block / Q000139:chemically induced; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000009:adverse effects*; D008875:Middle Aged; D014700:Verapamil / Q000009:adverse effects*
D014700:Verapamil; D008790:Metoprolol