[Blood myoglobin in children with progressive muscular dystrophy and in carriers].
We studied the behaviour of serum myoglobin in 32 children affected by Duchenne muscular dystrophy, in 30 mothers (10 definite carriers and 20 possible carriers), in 5 sisters (possible carriers) and in 40 healthy women (control). The serum myoglobin was always increased in the patients affected by Duchenne muscular dystrophy; the greatest values were in the patients who were still ambulant, with a behaviour similar to creatine kinase. In the carriers the myoglobinemia showed a significant increase in definite carriers, while there was no significant difference between the possible carriers and the controls.
D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000097:blood* / Q000201:enzymology; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000378:metabolism; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009136:Muscular Dystrophies / Q000097:blood* / Q000201:enzymology; D009211:Myoglobin / Q000097:blood*
D007527:Isoenzymes; D009211:Myoglobin; D003402:Creatine Kinase
La mioglobinemia in bambini affetti da distrofia muscolare progressiva e portatrici.