title: Bacteriological assistance for optimal antibiotic therapy of endocarditis.
abstract: The specific anatomical changes of the infected valvular tissue demand the best bactericidal antibiotic therapy of endocarditis. However, quantitative antibiotic sensitivity testing and determination of the bactericidal effectiveness is not sufficiently routinely practised. It is presented how appropriate bacteriological assistance to achieve the optimum antibiotic therapy for endocarditis leads to favourable clinical results. Establishment of reference laboratories for quantitative antibiotic sensitivity testing in every case of endocarditis is proposed. Active cooperation between these centres would provide excellent data for method and result comparison.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D006801:Humans; D008826:Microbial Sensitivity Tests; D013291:Streptococcus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents