title: Consistency of the tobacco withdrawal syndrome.
abstract: The consistency of the tobacco withdrawal syndrome across repeated periods of abstinence was tested using a modified A-B-A-B design. The large majority of the signs and symptoms of tobacco withdrawal occurred during abstinence, returned to baseline, and then recurred during a second abstinence period. This finding suggests that the syndrome is reliable and can be studied with within-subject designs.
mesh_terms: D006801:Humans; D009538:Nicotine / Q000009:adverse effects; D011581:Psychological Tests; D012008:Recurrence; D012907:Smoking; D013375:Substance Withdrawal Syndrome / Q000209:etiology* / Q000523:psychology
chemical_list: D009538:Nicotine