Amyloidosis in a case of canine systemic lupus erythematosus.
Concurrent systemic lupus erythematosus (SLE) and amyloidosis (renal and splenic) are reported in a 7-year-old female miniature Schnauzer. Treatment of tissue sections with potassium permanganate and dilute sulphuric acid prior to staining with Congo red indicated that the amyloid in this case is composed of AA protein (i.e. reactive systemic amyloid or so-called secondary amyloid). The rare association of amyloidosis and SLE, in both man and the dog, and the association with granulomatous pneumonia and leukopenia in this case are discussed.
D000686:Amyloidosis / Q000150:complications* / Q000662:veterinary; D000818:Animals; D004283:Dog Diseases; D004285:Dogs; D007668:Kidney / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000662:veterinary; D000685:Serum Amyloid A Protein / Q000032:analysis; D013154:Spleen / Q000032:analysis
D000685:Serum Amyloid A Protein