[Functional and biochemical characteristics of 2 types of diabetes mellitus].
Examination of 68 patients with diabetes mellitus of two types (insulin-dependent and insulin-independent) has shown that insulin-dependent diabetes mellitus is marked by more remarkable alterations in the microcirculation (according to capillaroscopy of the nailbed and ophthalmoscopy) as compared with the insulin-independent pattern, as well as by activation of lipid peroxidation. Free radical oxidation appears to play a role in the pathogenesis of microcirculatory disorders, making it necessary to administer antioxidants to diabetes mellitus patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000503:physiopathology; D005260:Female; D005609:Free Radicals; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D008875:Middle Aged; D009262:Nails / Q000098:blood supply; D010084:Oxidation-Reduction
D005609:Free Radicals; D008054:Lipid Peroxides
Funktsional'naia i biokhimicheskaia kharakteristika dvukh tipov sakharnogo diabeta.