[Determination of antibody titers in subjects passively immunized with specific anti-hepatitis B gamma globulins].
The authors have evaluated the effects of specific Immunoglobulins administration in order to prevent type B viral hepatitis. 34 members of care units entered a program of epidemiological surveillance after an occasional contamination with biological samples obtained from patients affected by type B viral hepatitis. All these subjects have been treated with two injections of specific immunoglobulins at the dose of 0.06 ml/kg. i.m.; the first was administered immediately after contamination and the second after one month. Serum antibody titres were determined by RIA techniques in a six months follow-up. The results seem to indicate that the degree of protectivity after passive immunization is poor and rather incostant.
D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000032:analysis / Q000276:immunology; D006801:Humans; D007116:Immunization, Passive; D008297:Male
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens
Valutazione dei titoli anticorpali adottivi in soggetti sieroprofilassati con gamma globuline specifiche anti-epatite B.