No inhibition of the lymphocyte transformation by pregnancy-associated alpha 2-glycoprotein (PAAG).
Fractions of retroplacental sera containing pregnancy-associated alpha 2-glycoprotein (PAAG) inhibited the lymphocyte transformation. The inhibitory effect did not correlate to the amount of this protein. It remained even after a specific depletion of the PAAG without altering the composition of the other proteins in the sera fractions. These results rule out a suppressive activity of the PAAG in the lymphocyte transformation.
D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D010835:Phytohemagglutinins / Q000494:pharmacology; D011257:Pregnancy Proteins / Q000494:pharmacology*
D010835:Phytohemagglutinins; D011257:Pregnancy Proteins