title: [Age-related changes in the immunoglobulins of human blood serum].
abstract: It has been shown that the content of G and A immunoglobulin (IgG, IgA) in blood serum increases with human age. IgM quantity is maximum at child age and at old age (about 80 years old and elder), at the age of 15-20 it is minimum. Immunoglobulin concentration is higher in female's blood serum than in male's, particularly at middle and old ages. The role of X-chromosome in regulation of serum IgM concentration is being discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007223:Infant; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012016:Reference Values; D012727:Sex Characteristics
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Vozrastnye izmeneniia kontsentratsii immunoglobulinov v syvorotke krovi cheloveka.