Biotransformation of olivetol by Syncephalastrum racemosum.
A study of the biotransformation of olivetol by Syncephalastrum racemosum ATCC 18192 has led to the isolation of three metabolites, which were identified as 4'-hydroxy-olivetol, 3-(3,5-dihydroxyphenyl)-1-propanol, and 3-(3,5-dihydroxyphenyl)-1-propanoic acid. The structures of the isolated metabolites were deduced by comparison of their spectral properties (pmr, cmr, ms) with those of olivetol. The absolute configuration of 4'-hydroxy-olivetol was determined to be R by the Horeau partial resolution method. Biotransformation of olivetol therefore appears to occur by a subterminal oxidation process.
D001711:Biotransformation; D006900:Hydroxylation; D013058:Mass Spectrometry; D009090:Mucorales / Q000378:metabolism*; D012118:Resorcinols / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013237:Stereoisomerism
D012118:Resorcinols; C016630:olivetol