title: Improved synthesis of 5 beta-cholestane-3 alpha,7 alpha,12 alpha, 26(27)-tetrol isomers from cholic acid.
abstract: Synthesis of a mixture of the 25(R) and 25(S) isomers of 5 beta-cholestane-3 alpha,7 alpha,12 alpha, 26(27)-tetrol from cholic acid in four steps, including a Wittig reaction, is described.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D002777:Cholestanols / Q000138:chemical synthesis*; D019826:Cholic Acid; D002793:Cholic Acids; D008401:Gas Chromatography-Mass Spectrometry; D013237:Stereoisomerism
chemical_list: D002777:Cholestanols; D002793:Cholic Acids; C020262:cholestane-3,7,12,26-tetrol; D019826:Cholic Acid