Metabolites of microorganisms. 229. Absolute configuration of naphthomycin A determined by X-ray analysis and chemical degradation.
The relative and absolute configurations of naphthomycin A were elucidated by an X-ray structural analysis of a methylation product, 25-O-methylnaphthomycin A iminomethyl ether. The absolute configuration was confirmed by degradation (O3, NaBH4) to (S)-butane-1,2,4-triol.
D000900:Anti-Bacterial Agents; D008968:Molecular Conformation; D009285:Naphthoquinones; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C010252:naphthomycin