Blood n-hexane concentration following acute inhalation exposure in rats.
Blood n-hexane concentrations in rats is reported. Groups of four rats were exposed to a n-hexane vapor/air mixture, in a glass chamber. At the end of the exposure, the animals were sacrificed by decapitation, blood was collected, and the concentration of n-hexane in blood was determined by headspace gas chromatography. Results indicate that blood becomes saturated with n-hexane in 10 minutes or less and persisted in the other exposure periods, up to and including 30 minutes.
D000395:Air Pollutants, Occupational / Q000633:toxicity; D000818:Animals; D002849:Chromatography, Gas / Q000379:methods; D006586:Hexanes / Q000097:blood* / Q000633:toxicity; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D000395:Air Pollutants, Occupational; D006586:Hexanes; C026385:n-hexane