The effectiveness of levamisole hydrochloride against the microfilaria of Dirofilaria immitis.
Levamisole hydrochloride was an efficient microfilaricide when used in dogs at a dosage of 10 mg/kg twice daily for 14 days. Increasing the dose rate every 3 days to 10 mg/kg twice daily and maintaining it at 10 mg/kg twice daily for a further 8 days, was also effective but a dosage of 5 mg/kg twice daily for 21 days was less effective and a dose rate of 20 mg/kg was efficient, but toxic.
D000818:Animals; D004184:Dirofilariasis / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy / Q000469:parasitology*; D004285:Dogs; D007978:Levamisole / Q000008:administration & dosage* / Q000627:therapeutic use; D008842:Microfilariae / Q000187:drug effects; D013997:Time Factors
D007978:Levamisole