title: [Regional cerebral blood flow analysis by 133Xe intraarterial injection method. A comparison with cerebral infarction and cerebrovascular dementia].
abstract: Nine cases of cerebral infarction (cerebrovascular dementia 4 cases, hemiparesis 4, aphasia 1) were investigated by intraarterial 133Xe injection. Eight of the cases were male and one was female. Ages ranged from 38 to 72, with a mean age of 57.6 years. Two criteria were necessary for a diagnosis of cerebrovascular dementia: the presence of cerebrovascular disease and a score of less than 20 on Hasegawa's dementia scale. Cases of cerebrovascular dementia tended to have a lower mean cerebral blood flow (CBF) value on the white matter by two-compartmental analysis. Two of the five brain areas showed statistically significant differences. These results support the modern theory that cerebrovascular dementia appears as a result of a disturbance of the white matter. Cases of cerebrovascular dementia showed a lower mean CBF value with a coefficient of variance of regional distribution by height over area method. This showed that CBF values in cerebrovascular dementia were generally low and the range of values were narrow. In a comparison of regional CBF and cerebral angiographical findings, cases of cerebrovascular dementia tended to have a lower mean CBF value in proportion to the severity of angiographical findings. In addition, regional CBF showed a tendency to agree closely with angiographical findings.
mesh_terms: D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000503:physiopathology; D003704:Dementia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D014980:Xenon Radioisotopes / Q000008:administration & dosage
chemical_list: D014980:Xenon Radioisotopes