title: Quantitation of the immunoglobulins in reproductive tract secretions of the mare.
abstract: IgG, IgA, IgM and albumin concentrations were measured in serum, follicular fluid and oviductal, uterine and intestinal secretions of the horse. Follicular protein concentrations were found to be dependent on serum concentration and molecular size. Of the immunoglobulins only IgG was detectable in oviductal secretions, but IgG:albumin ratios did not differ significantly from those in serum. IgG, IgA and IgM were measured in uterine secretions, with IgG predominant. Serum transudation into uterine secretions was minimal. In intestinal secretions, IgA levels were slightly higher than IgG, with albumin and IgM at low levels. In five mares with histories of chronic metritis, IgG, IgA and albumin concentrations were significantly elevated in uterine secretions.
mesh_terms: D000418:Albumins / Q000032:analysis; D000818:Animals; D001826:Body Fluids / Q000276:immunology*; D004971:Estrus; D005187:Fallopian Tubes / Q000378:metabolism; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism*; D006736:Horses / Q000276:immunology*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D007419:Intestinal Secretions / Q000276:immunology; D006080:Ovarian Follicle / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal; D011506:Proteins / Q000032:analysis; D012709:Serum Albumin / Q000032:analysis; D014599:Uterus / Q000378:metabolism
chemical_list: D000418:Albumins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D011506:Proteins; D012709:Serum Albumin