[Immunological indices and the acid phosphatase activity of the blood serum in patients with suppurative and destructive complications of acute pneumonia during the treatment/process].
The content of T and B lymphocytes, IgA, IgM and IgG as well as blood serum acid phosphatase (AP) activity were examined in 55 patients with purulent destructive complications of acute pneumonia. The patients were distributed into 2 groups depending on the disease gravity. The patients with a grave disease showed the depression of T and B immunity systems, marked deficiency of serum IgA, IgM and IgG. The percentage and absolute number of O cells was increased according to the disease gravity. In second group patients with a less graver disease, the reduction in the analogous immunity indicators was statistically insignificant. The disease ran the gravest course (with the development of pulmonary and extrapulmonary complications) in subjects with chronic alcoholism. The level of AP was the highest in disseminated destructive process and in diseases complicated by pleural empyema. During the convalescence, the AP activity descended, however it remained higher than normal in the presence of residual dry destructive cavities.
D000135:Acid Phosphatase / Q000097:blood*; D000208:Acute Disease; D000328:Adult; D000917:Antibody Formation; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D008169:Lung Abscess / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications / Q000276:immunology* / Q000628:therapy; D013183:Sputum / Q000382:microbiology
D007136:Immunoglobulins; D000135:Acid Phosphatase
Nekotorye immunologicheskie pokazateli i aktivnost' kisloĭ fosfatazy syvorotki krovi u bol'nykh s gnoĭno-destruktivnymi oslozhneniiami ostroĭ pnevmonii v protsesse lecheniia.