title: [Toxicologic survey of findings in putrefied corpses. Corpse putrefaction in air].
abstract: Autopsies were conducted on 234 putrefied corpses (exposed to the air, not buried) at the Institute for Forensic Medicine of the University of Hamburg from January 1979 to May 1983. Estimating the time it had taken to reach the respective degree of putrefaction was almost impossible. Only anamnestic clues provided evidence to ascertain the approximate time of death (between 3 days and 46 months ago). The cadavers were found in different locations: outdoors, inside heated or non-heated rooms. Some corpses wore clothes; others were naked; some were covered with blankets or other material. Chemicotoxicological analyses consisted of routine methods and additional modern sophisticated techniques: capillary gas chromatography, combined GC/MS, infrared spectrometry, radio- and enzyme-immunological tests. In organ specimens and body fluids of 47 corpses organic medicaments or poisons could be detected. Nearly all of these 47 forensic autopsies were carried out by request of the legal authorities to rule out legal intoxication as well as the influence of illegal drugs or medicaments. Unlike 20 years ago, today it is possible to detect and quantify organic drugs and poisons as well as their metabolic products, especially minor or major tranquilizers or barbiturates, in highly putrefied specimens. In spite of analytical progress, interpretation of some chemotoxicological results remains difficult. Poor anamnestic data provide insufficient clues. Therefore, pathologicoanatomical and histological results have special significance for the final conclusions. Good cooperation between the pathologist and toxicologist is one of the imperative prerequisites to come to a satisfying result.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001463:Barbiturates / Q000378:metabolism; D001711:Biotransformation; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009294:Narcotics / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011041:Poisoning / Q000473:pathology*; D011042:Poisons / Q000378:metabolism*; D011180:Postmortem Changes; D011619:Psychotropic Drugs / Q000378:metabolism; D013405:Suicide
chemical_list: D001463:Barbiturates; D009294:Narcotics; D004364:Pharmaceutical Preparations; D011042:Poisons; D011619:Psychotropic Drugs
vernacular_title: Toxikologische Befunderhebungen an Fäulnisleichen. Leichenfäulnis an der Luft.