title: Wells' syndrome: is there collagen damage in the flame figures?
abstract: Flame figures are a characteristic histologic feature of Wells' syndrome (eosinophilic cellulitis). In this light and electron microscopic study, the ultrastructure of flame figures is described. Collagen fibers were encrusted with free eosinophil granules. No collagen damage was found. Flame figures most probably represent a transient result of unusual eosinophil activity.
mesh_terms: D000368:Aged; D003094:Collagen / Q000502:physiology*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004804:Eosinophils / Q000648:ultrastructure; D004890:Erythema / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000648:ultrastructure; D013577:Syndrome; D014581:Urticaria / Q000150:complications* / Q000473:pathology
chemical_list: D003094:Collagen