title: Estimate to mutation rates.
abstract: The mathematical methods for estimating the mutation rates of microbes at the level of populations are given in this paper, which are concerned with the estimation of the mixture of two normal distributions. Using the feed forward of livingthing's prior information, the precision of the estimates may be increased and the calculation may be reduced. Finally, an approximate method about the small sample is given in this paper.
mesh_terms: D008957:Models, Genetic; D009154:Mutation; D011336:Probability; D013302:Streptomyces / Q000235:genetics*