[Pharmacokinetics of naftidrofuryl in multimorbidity in geriatric patients].
The present pharmacokinetic study of a drug used in geriatric patients with multiple diseases reveals that the half-life in the elderly was extended for about three times as long as in the corresponding control group. There are significant positive as well as negative correlations between the kinetic data and routine parameters of the metabolism. These statistical correlations should be controlled by experimental studies.
D000368:Aged; D001711:Biotransformation; D002544:Cerebral Infarction / Q000097:blood / Q000188:drug therapy; D003704:Dementia / Q000097:blood / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005663:Furans / Q000097:blood*; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008111:Liver Function Tests; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D009257:Nafronyl / Q000009:adverse effects / Q000097:blood* / Q000627:therapeutic use
D005663:Furans; D009257:Nafronyl
Pharmakokinetik von Naftidrofuryl bei multimorbiden geriatrischen patienten.