Determinants of chlormethiazole-induced EEG effects in chronic alcoholics.
At beginning and end of hospital treatment with chlormethiazole (Distraneurin), the EEGs of 41 male alcoholics were analyzed, employing spectral analysis and Hjorth's parameters. Hierarchical regression analysis of selected data showed significant influence of hallucinations and/or personality deterioration on chlormethiazole-induced EEG effects, especially at the beginning of treatment.
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy* / Q000503:physiopathology; D002719:Chlormethiazole / Q000009:adverse effects* / Q000627:therapeutic use; D004569:Electroencephalography; D006212:Hallucinations / Q000503:physiopathology; D006801:Humans; D010551:Personality
D002719:Chlormethiazole