title: [Significance of atrioventricular block in the development of the Wolff-Parkinson-White syndrome].
abstract: The vegetative homeostasis was studied in 49 children with the Wolff-Parkinson-White (WPW) syndrome and in their relatives. To control the WPW syndrome the authors used clino-orthostatic and drug (atropine and gilurytmal) tests. In 85.7% of children with WPW syndrome there was a vagotonic orientation of the vegetative tonus, not infrequently of the hereditary nature, inducing inhibition of atrioventricular conductivity. A combination of the atrioventricular block of the first stage and the WPW syndrome in 44.1% of the children and in 51.2% of their families points to an association between these phenomena. The detection of the WPW syndrome in the presence of sympathicotonia does not contradict this postulation since the atrioventricular node may be blocked by frequent impulses which helps to increase the conductivity along the additional pathways. In connection with the frequent detection of the additional conductive pathways in normal subjects, their first appearance in elderly age and their combination with block, a suggestion is made that the retention of the additional pathways in the myocardium may be advisable. Yet, being compensatory in their nature they may precipitate arrhythmias.
mesh_terms: D000293:Adolescent; D001283:Atrioventricular Node / Q000503:physiopathology; D001337:Autonomic Agents; D001341:Autonomic Nervous System / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D013564:Sympathetic Nervous System / Q000503:physiopathology; D014630:Vagus Nerve / Q000503:physiopathology; D014927:Wolff-Parkinson-White Syndrome / Q000235:genetics / Q000503:physiopathology*
chemical_list: D001337:Autonomic Agents
vernacular_title: Znachenie atrioventrikuliarnoĭ blokady v razvitii sindroma Vol'ffa-Parkinsona-Uaĭta.