Identification of differential drug responses and mechanism(s) of resistance in vincristine-resistant cell lines developed either by exposure to the drug or to fractionated radiation.
D000818:Animals; D000970:Antineoplastic Agents; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy; D002460:Cell Line; D004351:Drug Resistance / Q000528:radiation effects*; D006801:Humans; D007940:Leukemia L5178 / Q000188:drug therapy / Q000532:radiotherapy; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D014750:Vincristine / Q000378:metabolism / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D014750:Vincristine