[Fibrin deposits on the surface of tumorous and normal cells].
The paper describes morphological changes of normal and tumor cells in the process of interaction with plasma fibrinogen. Comparative study shows significant difference between normal and neoplastic cells in their capacity to bind fibrin. Normal FL cells are characterized by a moderate or low fibrin binding, while tumor CaOv cells by a more intensive uptake of fibrin, which deposits both on the cell surface and in the intercellular spaces. This difference is more pronounced in a long-term cell incubation with fibrinogen.
D000650:Amnion / Q000378:metabolism*; D002460:Cell Line; D002478:Cells, Cultured; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D005340:Fibrinogen / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D010051:Ovarian Neoplasms / Q000378:metabolism*
D005337:Fibrin; D005340:Fibrinogen
Ob otlozheniiakh fibrina na poverkhnosti opukholevykh i normal'nykh kletok.