The role of estrogen in migraine: a review and hypothesis.
The epidemiological, clinical and basic science evidence for a role of estrogen in migraine is reviewed. The hypothesis is put forward that estrogen exerts its influence by modulating sympathetic control of the cerebral vasculature.
D002560:Cerebrovascular Circulation; D004967:Estrogens / Q000502:physiology*; D005260:Female; D006801:Humans; D008572:Menarche; D008597:Menstrual Cycle; D008881:Migraine Disorders / Q000503:physiopathology*; D011374:Progesterone / Q000502:physiology; D011941:Receptors, Adrenergic / Q000502:physiology; D013564:Sympathetic Nervous System / Q000503:physiopathology; D014661:Vasoconstriction
D004967:Estrogens; D011941:Receptors, Adrenergic; D011374:Progesterone