title: Injectable ibuprofen: preliminary evaluation of its ability to decrease peritendinous adhesions.
abstract: Peritendinous adhesions continue to limit the full return of hand function following flexor tendon injury and repair. Pilot studies in rabbits demonstrated the ability of ibuprofen (Motrin) to reduce intra-abdominal adhesions. In this study, ibuprofen injected at the site of flexor tendon repair significantly reduced the restrictive effects of peritendinous adhesions in primates.
mesh_terms: D000818:Animals; D002921:Cicatrix / Q000517:prevention & control*; D006230:Hand Injuries / Q000188:drug therapy* / Q000601:surgery; D007052:Ibuprofen / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D007267:Injections; D008252:Macaca fascicularis; D013708:Tendon Injuries / Q000188:drug therapy* / Q000601:surgery; D000267:Tissue Adhesions / Q000188:drug therapy
chemical_list: D007052:Ibuprofen