title: Some applications of a graphical method for the comparative statistical study of vaccine potency assays.
abstract: Using examples drawn from some commonly-used methods for vaccine potency assay, we show how a graphical method of representing three key characteristics, precision, sensitivity and relevance, can be used to compare basic methods and variations in test design. We suggest that this method can be of considerable value to Control Authorities in establishing test designs and potency standards, and to vaccine manufacturers in formulating vaccines which will have a high probability of meeting these potency standards.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000517:prevention & control*; D005536:Foot-and-Mouth Disease / Q000276:immunology / Q000517:prevention & control*; D014613:Vaccines, Attenuated / Q000592:standards*; D014765:Viral Vaccines / Q000592:standards*
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines