title: "Local" treatment of early breast cancer.
abstract: T1N0 and T2N0 breast cancer should be treated initially by local excision only. Subsequent review of the patient's clinical, investigative, and histologic presentation must then guide future treatment decisions. If further treatment is deemed necessary, then consideration should be given to wider excision, total mastectomy, or local irradiation, in that order. Subsequent development of axillary lymphadenopathy signals disseminated disease and requires systemic, not local, therapy initially.
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local; D012086:Reoperation