Plasmid-mediated inducible reactivation of an actinophage.
The inducible Weigle-Reactivation (WR) of UV-irradiated bacteriophage VP5 has been examined in Streptomyces coelicolor A3(2) with and without the mutagenesis-enhancing SCP1 plasmid. A higher inducible reactivation was observed in SCP1+ strains ("free" plasmid) than in SCP1- strains and in NF strains (SCP1 integrated). The efficiency of the plasmid-mediated and cellular repair processes have been examined.
D001435:Bacteriophages / Q000235:genetics / Q000502:physiology* / Q000528:radiation effects; D004260:DNA Repair / Q000528:radiation effects; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral / Q000528:radiation effects; D010957:Plasmids; D013302:Streptomyces / Q000235:genetics*; D014466:Ultraviolet Rays
D004279:DNA, Viral