Experimental alveolar echinococcosis. Suitability of a murine model of intrahepatic infection by Echinococcus multilocularis for immunological studies.
An experimental model of human alveolar echinococcosis was developed, using intrahepatic injection of E. multilocularis larvae in mice differing by their sensitivity to this parasite; it seems to be suitable for studying the relationship between cell-mediated immunity and a) growth of the parasite, b) development of fibrosis.
D000818:Animals; D004195:Disease Models, Animal; D004444:Echinococcosis, Hepatic / Q000276:immunology* / Q000473:pathology; D004445:Echinococcosis, Pulmonary / Q000276:immunology* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D008806:Mice, Inbred AKR; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA