title: Biological and chemical properties of left handed Z-DNA.
abstract: Left handed Z-DNA has been demonstrated to be a stable new conformation which occurs at certain types of DNA sequences in recombinant plasmids. DNA supercoiling, as well as a number of environmental conditions, stabilizes this unusual conformation. The biological significance of left handed DNA will be discussed.
mesh_terms: D001483:Base Sequence; D004247:DNA; D004278:DNA, Superhelical; D008745:Methylation; D009690:Nucleic Acid Conformation; D013816:Thermodynamics
chemical_list: D004278:DNA, Superhelical; D004247:DNA