title: Sports science and body composition analysis: emphasis on cell and muscle mass.
abstract: Because we are unsure of many of the constants that we use in the calculation of components of body composition, there is a need for a greater number of postmortem analyses in order to prepare better equations for more accurate utilization of indirect noninvasive measurements. At present, most investigators who study active people (including athletes) use techniques that only provide an approximation of body fatness. Because excess fat serves as a burden to the body during transport in the performance of many physical activities, fatness constitutes a variable of concern. Fat-free body weight is usually calculated by difference and serves as a reference for some physiological functions. Although fat-free weight and lean body mass are not the same, most investigators calculate fat-free weight and many use the terms interchangeably. Some of the assumptions and problems in utilizing hydrodensitometry in the calculation of body fatness remain unresolved, such as the true densities of the different gross components of body composition in the young, aged, physically fit, etc. A variety of body composition profiles of different athletes have been published in recent years, which substantially augment efforts initiated in the 1940s and 1950s. The regular employment of a total body water assessment along with hydrodensitometry would improve the accuracy of calculation of body fatness, but the procedure is somewhat expensive in cost and time of subject involvement. In order to extend our knowledge of body composition and to quantitatively ascertain the mass of skeletal muscle, some of the procedures for calculating cell and muscle mass are reviewed including total body potassium, total body nitrogen, creatinine excretion, and 3-methylhistidine excretion. These procedures reveal important information, but require further investigation before we are confident that we are measuring cell or muscle mass. We have focused on 3-methylhistidine excretion because preliminary investigation suggests that it may reveal differences in muscle mass not detected by densitometry.
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology; D000328:Adult; D000368:Aged; D001823:Body Composition; D001834:Body Water; D001835:Body Weight; D003404:Creatinine / Q000378:metabolism; D003720:Densitometry; D005260:Female; D006801:Humans; D008297:Male; D008762:Methylhistidines / Q000032:analysis / Q000378:metabolism; D008875:Middle Aged; D009132:Muscles / Q000032:analysis; D009501:Neutron Activation Analysis; D009584:Nitrogen / Q000032:analysis; D011188:Potassium / Q000032:analysis; D013177:Sports
chemical_list: D008762:Methylhistidines; D003404:Creatinine; C028118:3-methylhistidine; D009584:Nitrogen; D011188:Potassium