title: [Coagulation factor XII deficiency, a contribution to thrombophilia].
abstract: The hereditary deficiency of Hageman's factor rarely occurs. The patients are mostly detected by chance. The leading symptom is the considerably prolonged partial thromboplastin time. A haemorrhagic diathesis is not present. Since in these patients thromboemoblic diseases are possible, in an ascertained diagnosis the prevention of thrombosis should be performed.
mesh_terms: D003937:Diagnosis, Differential; D005174:Factor XII / Q000378:metabolism*; D005175:Factor XII Deficiency / Q000097:blood* / Q000235:genetics; D006801:Humans; D010314:Partial Thromboplastin Time; D013927:Thrombosis / Q000097:blood*
chemical_list: D005174:Factor XII
vernacular_title: Zum Problem des Gerinnungsfaktor XII-Mangels, ein Beitrag zur Thrombophilie.