Determination of phenylbutazone in tablets by nuclear magnetic resonance spectrometry.
A method for the quantitative analysis of phenylbutazone in tablets using NMR is reported. The method is both accurate and precise. Using synthetic mixtures, the mean recovery value +/- SD was 100.5 +/- 0.86%. The NMR results of commercial preparations are compared with those obtained by the USP XX procedure. The NMR spectrum, in addition, provides a very specific means of identification for phenylbutazone.
D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010653:Phenylbutazone / Q000032:analysis*; D013607:Tablets
D013607:Tablets; D010653:Phenylbutazone