title: PD 114,759 and PD 115,028, novel antitumor antibiotics with phenomenal potency. I. Isolation and characterization.
abstract: The isolation of two new antibiotics, PD 114,759 and PD 115,028, exhibiting in vivo antitumor activity at extremely low doses is described. The physico-chemical properties of these sulfur-containing compounds show that they represent a novel class of antitumor agents.
mesh_terms: D000192:Actinomycetales / Q000378:metabolism; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification*; D001688:Biological Products; D005285:Fermentation
chemical_list: D000903:Antibiotics, Antineoplastic; D001688:Biological Products; C044530:veractamycin A; C044531:veractamycin B