title: Furosemide effect on penicillin induced convulsions.
abstract: Convulsions were induced in 20 cats by the administration of intravenous penicillin. Furosemide administered together and after penicillin failed to reduce the seizure activity. Penicillin brain concentrations were not reduced by furosemide. Penicillin induced seizures are not affected by furosemide.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D002415:Cats; D005665:Furosemide / Q000494:pharmacology* / Q000627:therapeutic use; D010400:Penicillin G / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000633:toxicity*; D012640:Seizures / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D005665:Furosemide; D010400:Penicillin G