The mesencephalic locomotor region (MLR) in the rat.
These studies demonstrate the presence of the MLR in the rat brain. Controlled locomotion on a treadmill could be induced by low level stimulation (less than 50 microA) of an area in the posterior midbrain following a precollicular-prenigral brainstem transection. This area included the lateral part of the cuneiform nucleus and anterior as well as posterior portions of the pedunculopontine nucleus. In addition, the presence of a subthalamic locomotor region in the fields of Forel was determined in rats after prethalamic transections.
D000818:Animals; D001931:Brain Mapping; D002415:Cats; D004558:Electric Stimulation; D008636:Mesencephalon / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D013378:Substantia Nigra / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000502:physiology
D005680:gamma-Aminobutyric Acid