[Elimination of admixtures from antibiotic sediments during their treatment with solvents].
A model for determination of the admixture concentration in the secondary mother solution was developed. The concentration was determined depending on the solvent volume used for repulping the precipitate and on the impurity level of the initial antibiotic paste. When the values of X1 and X2 are known it is possible to estimate the amount of the admixtures remaining in the paste layer after separation of the secondary mother solution with regard to the volume of the latter in the precipitate pores. Optimization of paste repulping should be considered in combination with displacement washing and the apparatus used for separation of the phases, as well as the requirements for the purity level of the finished product.
D000085:Acetates; D019342:Acetic Acid; D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D000440:Butanols; D011232:Chemical Precipitation; D004340:Drug Contamination / Q000517:prevention & control*; D005374:Filtration / Q000379:methods; D010400:Penicillin G / Q000302:isolation & purification; D012997:Solvents
D000085:Acetates; D000900:Anti-Bacterial Agents; D000440:Butanols; D012997:Solvents; D019342:Acetic Acid; D010400:Penicillin G
Udalenie primeseĭ iz osadkov antibiotikov pri obrabotke ikh rastvoriteliami.