Nephropathy in Indian patients with non-insulin-dependent diabetes in the young.
In 85 patients diagnosed as having non-insulin-dependent diabetes in the young (NIDDY), 6 were found to have nephropathy. The duration of diabetes ranged from 2 to 17 yr; 5 of the 6 patients had retinopathy as evidenced by fluoroscein angiography (3 with proliferative changes). All 6 patients had a 24-h urinary protein excretion greater than 0.5 g and a glomerular filtration rate less than 80 ml/min. Serum beta 2-microglobulin levels were increased in all 6 patients, while only 3 had increased serum creatinine levels.
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000235:genetics; D003928:Diabetic Nephropathies / Q000209:etiology*; D003930:Diabetic Retinopathy / Q000209:etiology; D005260:Female; D006801:Humans; D007194:India; D007677:Kidney Function Tests; D008297:Male; D011507:Proteinuria / Q000209:etiology; D012306:Risk