[Value of spirometric, pneumotachographic and oscilloresistometric studies in the functional diagnosis of obstructive respiratory tract diseases].
Tests were conducted on 90 smokers and a control group of 20 non-smokers using not only simple spirometry but also pneumotachography and the forced oscillation technique, including flow- and resistance-volume graphs. FEV1 was proved to be a sensitive screening test for early recognition of disfunction in the region of the small airways. 39,5% of the younger light smokers already showed signs of impairment to the breathing mechanics indicating exobronchial obstruction. The heavy, mostly older, smokers frequently showed complex disfunction, and in 55,3% the oscillatory resistance revealed quantifiable endobronchial obstruction. The oscillatory flow-resistance-increase-volume (as a percentage of vital capacity) proved the most sensitive small-airways-test during middle age, permitting significant distinction of smokers from non-smokers up to the age of 55.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000403:Airway Resistance; D001991:Bronchitis / Q000175:diagnosis; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis*; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D009991:Oscillometry / Q000379:methods*; D011656:Pulmonary Emphysema / Q000175:diagnosis; D012907:Smoking; D013147:Spirometry / Q000379:methods*
Zur Wertigkeit spirometrischer, pneumotachographischer und oszilloresistometrischer Untersuchungen in der funktionellen Basisdiagnostik von obstruktiven Atemwegserkrankungen.