Estimating the recombination frequency for the MN and the Ss loci.
Linkage analysis of 146 informative families for MN and Ss resulted in an estimate of the recombination frequency greater than previously reported. Our total is 7 recombinant children out of 467 individuals, including 1 confirmed recombinant (retested and HLA-compatible) and 6 not verified. The 95% confidence interval of our estimate of recombination is 0.0033-0.0167. Our results are compared with two earlier studies.
D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D006801:Humans; D008126:Lod Score; D008951:MNSs Blood-Group System / Q000235:genetics*; D008297:Male; D011995:Recombination, Genetic
D008951:MNSs Blood-Group System