[Effect of microelectrophoretic application of GABA on the formation of a cellular analog of a conditioned reaction].
Influence of GABA application on ability of sensorimotor cortical neurones to form conditioned cellular reactions was studied in chronic experiments on rabbits. Neuronal reactions were analysed at the initial stage of eye-lid conditioning. GABA application in a period of presentation of paired conditioned and unconditioned stimuli disturbed formation of inhibitory conditioned cellular reactions and did not influence elaboration of activating responses. Plastic changes underlying the process of formation of inhibitory conditioned neuronal reactions are supposed to be of intracortical nature.
D000818:Animals; D003215:Conditioning, Eyelid / Q000187:drug effects*; D005108:Extinction, Psychological / Q000187:drug effects; D007478:Iontophoresis; D008845:Microinjections; D008959:Models, Neurological; D009044:Motor Cortex / Q000187:drug effects*; D010812:Physical Stimulation; D011817:Rabbits; D013003:Somatosensory Cortex / Q000187:drug effects*; D013016:Sound; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid
Vliianie mikroélektroforeticheskoĭ applikatsii GAMK na formirovanie kletochnogo analoga uslovnoĭ reaktsii.