title: Spontaneous remission and its significance for trials in primary prevention of hypertension.
abstract: The hypothesis that salted food can cause hypertension must be tested prospectively to see if unsalted food protects non-hypertensive persons. The first of two feasibility studies has confirmed that established hypertension can show spontaneous remission on unsalted food. We now report the preliminary findings of a second feasibility study to test whether a clinic for hypertension can attract self-referred non-hypertensive people interested in preventing hypertension by changing their diet. A total of 874 applicants have attended at least one pre-entry visit. We report data from the first 176 participants who completed the feasibility study lasting 12 weeks. Of these 110 were non-hypertensive people and 93 (84.5%) would be prepared to remain on unsalted food for five years.
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D004039:Diet, Sodium-Restricted; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D011322:Primary Prevention; D012075:Remission, Spontaneous; D012964:Sodium / Q000652:urine
chemical_list: D012964:Sodium; D011188:Potassium