Study of mutagenic pollution in Bombay.
Airborne suspended particulate matter (SPM) from seven areas in and around Bombay city were collected over glass fibre filters (0.8 micrometer porosity). The chemicals from the SPM were extracted in dimethylsulfoxide and distilled water and were further tested for mutagenicity by Ames' test using for five mutants of Salmonella typhimurium. Of the seven areas studied, only four exhibited mutagenicity, which was confirmed by dose-response assays using the mutant strain TA 100. The very high mutagenicity observed in central Bombay correlates with the higher incidence of respiratory tract diseases in the resident population.
D000393:Air Pollutants / Q000009:adverse effects*; D007194:India; D009152:Mutagenicity Tests; D009153:Mutagens
D000393:Air Pollutants; D009153:Mutagens