Detection of antispermatozoal antibodies of IgG, IgA, and IgM immunoglobulin classes in cervical mucus.
The immunobead test (IBT) was applied to bromelin-treated cervical mucus (CM) samples from 78 infertile women. Seven (8.9%) of the patients were positive for IgG and/or IgA class antibodies, whilst none (0/35) were found positive for IgM class antibodies. We found that 57% of the positive samples contained IgG and IgA classes, whilst the remaining samples contained IgA alone. The implications of these results were discussed.
D002582:Cervix Mucus / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification; D007074:Immunoglobulin G / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000302:isolation & purification; D007136:Immunoglobulins / Q000302:isolation & purification*; D007247:Infertility, Female / Q000276:immunology; D008297:Male; D013081:Sperm Motility; D013094:Spermatozoa / Q000276:immunology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins