title: Improved method for the synthesis of phosphatidylcholines.
abstract: An improved method for the synthesis of phosphatidylcholines from phosphatidic acid and choline is described. The technique utilizes the tetraphenylborate salt of choline together with the condensing agent 2,4,6-triisopropylbenzenesulfonyl chloride. The yields in the reaction are consistently in the range 70-75%.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D002794:Choline; D004134:Dimyristoylphosphatidylcholine / Q000138:chemical synthesis; D010713:Phosphatidylcholines / Q000138:chemical synthesis*; D013775:Tetraphenylborate
chemical_list: D010713:Phosphatidylcholines; D013775:Tetraphenylborate; D002794:Choline; D004134:Dimyristoylphosphatidylcholine