title: [A new material in neurosurgery].
abstract: A new alcoholic prolamine solution is now available (ETHIBLOC, supplied by Ethicon, Norderstedt) which can be used in neurosurgery for a variety of purposes. This material hardens quickly in an aqueous medium. Animal experiments have not shown any damaging action on the brain, meninges, or bone. The excellent tolerance of the material was seen in a total of 22 patients operated on with the help of Ethibloc. It is particularly well suited for closing frontal CSF fistulas, incised frontal sinuses, and for rearranging or shunting in case of cerebral vascular deformities. It can also be used as a carrier of antibiotics in osteomyelitis, for covering up minor defects of the dura mater, for dura sealing, and for closing the bone after trephination. The preparation is transformed completely to connective tissue within a period of 40 to 90 days. New techniques of surgery are described which have become possible by the use of Ethibloc.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001927:Brain Diseases / Q000601:surgery*; D002558:Cerebrospinal Fluid Otorrhea / Q000601:surgery; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery; D003973:Diatrizoate; D004338:Drug Combinations; D004388:Dura Mater / Q000601:surgery; D005227:Fatty Acids; D006407:Hematoma, Epidural, Cranial / Q000601:surgery; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery; D010019:Osteomyelitis / Q000601:surgery; D011409:Propylene Glycols; D011506:Proteins / Q000627:therapeutic use*; D011817:Rabbits; D051381:Rats; D012887:Skull Fractures / Q000601:surgery; D014945:Wound Healing / Q000187:drug effects; D015028:Zein
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D005227:Fatty Acids; D011409:Propylene Glycols; D011506:Proteins; D003973:Diatrizoate; D015028:Zein; C020481:alcoholic prolamine solution
vernacular_title: Ein neuer Werkstoff in der Neurochirurgie.