[Malignant transformation of mouse cultured cells using bovine adenovirus type 3 and modification of this process by MNNG].
It is shown that tumour transformation of cultured mouse cells 10T1/2C3H depends on the time after the infection with virus BAV-3. The maximal number of tumours was observed 3 weeks after infection, then the frequency of tumours was reduced. MNNG modified virus-induced tumour cell transformation differently depending on the time between cell infection and treatment with the chemical agent.
D000256:Adenoviridae; D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D002472:Cell Transformation, Viral / Q000187:drug effects*; D002478:Cells, Cultured; D008769:Methylnitronitrosoguanidine; D051379:Mice; D008809:Mice, Inbred C3H; D012513:Sarcoma, Experimental / Q000209:etiology; D013997:Time Factors
D008769:Methylnitronitrosoguanidine
Zlokachestvennaia transformatsiia kul'tiviruemykh kletok myshi bych'im adenovirusom tipa 3 i modifikatsiia étogo protsessa MNNG.