title: Efficacy of furazolidone in grower diets on subsequent performance of swine--a cooperative study.
abstract: Nine experiments were conducted at three stations to evaluate the efficacy of furazolidone as a growth promoter in diets for young swine and to determine if an early growth response is maintained after the additive is withdrawn from the diet. A total of 528 pigs (24 replications, 132 pigs/treatment) initially averaging 12 kg body weight were fed a nonmedicated basal diet or a diet with 110 ppm furazolidone for 5 wk, 165 ppm furazolidone for 3 wk or 220 ppm furazolidone for 2 wk. After withdrawal of furazolidone, the basal diet was fed to the end of the test, at which time the pigs averaged 93 kg. During the initial 2-wk period, pigs fed furazolidone gained 15.4% faster (P less than .001) and required 8% less (P less than .001) feed per unit of gain than control pigs fed the nonmedicated diet. At 5 wk, pigs previously fed furazolidone gained 8.4% faster (P less than .001) and 4.5% more efficiently (P less than .001) than controls. By 10 wk, pigs previously fed furazolidone maintained a slight advantage in growth rate over controls (2.6%, P less than .10), but feed/gain responses were similar for the two groups. By the end of the experiment, the early growth response from furazolidone was completely lost. Although there were differences in growth responses among stations, the treatment response patterns were similar for each station, with no evidence of a treatment X station interaction.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000375:Aging; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005260:Female; D005503:Food Additives; D005664:Furazolidone / Q000494:pharmacology*; D008297:Male; D009026:Mortality; D013552:Swine / Q000502:physiology*
chemical_list: D005503:Food Additives; D005664:Furazolidone