Cerebrospinal fluid creatine kinase activity and neurologic recovery after cardiac arrest.
We evaluated prospectively the relation between cerebrospinal fluid creatine kinase activity (CSF CK) and neurologic recovery after out-of-hospital cardiac arrest. Without knowledge of the enzyme results, we determined whether patients awoke, followed commands, or had comprehensible speech. CSF CK was significantly higher in never-awakening than in awakening patients. After cardiac arrest, elevation of CSF CK predicts poor neurologic recovery.
D001921:Brain / Q000201:enzymology / Q000503:physiopathology*; D003243:Consciousness; D003402:Creatine Kinase / Q000134:cerebrospinal fluid*; D006323:Heart Arrest / Q000134:cerebrospinal fluid* / Q000150:complications; D006801:Humans; D014474:Unconsciousness / Q000134:cerebrospinal fluid / Q000209:etiology
D003402:Creatine Kinase