title: Potassium wasting and other renal tubular defects with rifampin nephrotoxicity.
abstract: Interstitial nephritis consequent to rifampin was associated with potassium wasting, an acidifying defect, high fractional uric acid excretion, and glucosuria, indicating a multiplicity of renal tubular transport abnormalities. Enlarged kidneys on sonogram and proteinuria were also observed.
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D006801:Humans; D007008:Hypokalemia / Q000209:etiology*; D007684:Kidney Tubules / Q000473:pathology; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D011188:Potassium / Q000378:metabolism; D012293:Rifampin / Q000009:adverse effects*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy; D014527:Uric Acid / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D014527:Uric Acid; D011188:Potassium; D012293:Rifampin