Machado-Joseph disease in an American-Italian family.
An American-Italian family is described as affected by an autosomal dominant inherited ataxia which meets the clinical diagnostic criteria for Machado-Joseph disease. This disorder no longer appears to be limited to individuals of known Portuguese ancestry.
D000328:Adult; D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000235:genetics*; D005799:Genes, Dominant; D006801:Humans; D007558:Italy / Q000208:ethnology; D008297:Male