title: [A computer model for the simulation of intra-arterial tumor therapy in the area of the external carotid artery].
abstract: The complex theoretical background of intra-arterial (i.a.) tumour therapy induced the installation of a computer assisted model based on the use of 7 variables, the most important factors being the blood flow of the infused organ and the clearance of the drug, as well as the tissue binding of the drug. Various relevant conditions of i.a. infusion are represented by simple but typical diagrams allowing quick orientation on the principles governing i.a. infusion even for those who are not very familiar with the theoretical background of i.a. infusion. The model represents an improvement in the individual planning of effective i.a. chemotherapy.
mesh_terms: D000970:Antineoplastic Agents / Q000097:blood / Q000627:therapeutic use*; D001682:Biological Availability; D002342:Carotid Artery, External; D003201:Computers; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*; D008657:Metabolic Clearance Rate; D008962:Models, Theoretical
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Ein Computer-Modell zur Simulation der intraarteriellen Tumortherapie im Bereich der A. carotis externa.