Multicentric pigmented Bowen's disease of the genitalia associated with carcinoma in situ of the cervix.
A case of multicentric pigmented Bowen's disease in a 45 year old woman with a previous history of carcinoma of the cervix is described. The two conditions may have a common pathogenesis, and a preceding viral infection with herpes simplex or human papillomavirus could be of aetiological relevance. Patients with multicentric pigmented Bowen's disease may be at risk of developing other tumours of the genital tract. Treatment with carbon dioxide laser proved effective.
D001913:Bowen's Disease / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D002278:Carcinoma in Situ / Q000150:complications*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D002583:Uterine Cervical Neoplasms / Q000150:complications*