Pancreatic tissue pressure: techniques and pathophysiological aspects.
Pancreatic tissue pressure (PTP) was measured during surgery in six patients with a normal pancreas and in six patients with chronic pancreatitis. The pressures were obtained by insertion of a tiny transducer-connected cannula into pancreas. PTP probably reflects acinus and small-duct pressure. PTP was significantly higher in patients with chronic pancreatitis than in patients with a normal pancreas, but it decreased significantly after drainage. A high degree of linear relationship between PTP and intraductal pressure (r = 0.99) indicates that PTP measurements are valuable when the main duct is difficult to cannulate. Chronic pancreatitis might be a compartment syndrome due to impeded drainage and an inelastic capsule.
D000368:Aged; D002908:Chronic Disease; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000502:physiology* / Q000503:physiopathology; D010183:Pancreatic Ducts / Q000502:physiology / Q000503:physiopathology; D010195:Pancreatitis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D011312:Pressure; D014160:Transducers, Pressure