Distribution of intraperitoneally injected [125I] BSA in cytoplasm, nucleoplasm and chromatin of lymphocyte-like and macrophage-like rat spleen cells.
[125I] BSA injected intraperitoneally penetrated into the cytoplasm and nucleoplasm of rat spleen cells, being rapidly and very tightly bound with chromatin. Distribution in lymphocyte-like and macrophage-like cells was quite similar, but in lymphocyte--like cells between the 4th and 8th day [125I] BSA was totally degraded, while in macrophage-like cells it was still present, being degraded between the 8th and 14th day.
D000818:Animals; D002417:Cattle; D002467:Cell Nucleus / Q000378:metabolism; D002843:Chromatin / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism*; D008264:Macrophages / Q000276:immunology / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012710:Serum Albumin, Bovine; D012711:Serum Albumin, Radio-Iodinated; D012965:Sodium Chloride / Q000494:pharmacology; D013154:Spleen / Q000276:immunology / Q000378:metabolism*
D002843:Chromatin; D012711:Serum Albumin, Radio-Iodinated; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride