title: [Carcinogenic effect of a heavy catalytic gas oil].
abstract: The carcinogenic effect of treatment with heavy catalytic gasoil on the skin of 120 albino noninbred mice was studied. Skin tumors arose in 97 of 115 animals (84.3%) which survived until the appearance of the first papillomas. In 21 mice, tumors were benign while cancer developed in 76 animals. 116 visceral neoplasms were detected in 99 animals (93.4%). They were found in the upper part of digestive tract of 57, the hematopoietic and lymphatic tissues of 57 and in the lungs of two animals. The study established a high carcinogenicity of heavy catalytic gasoil matched by early appearance and multicentric growth of tumors as well as rapid generalization of the process.
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced / Q000473:pathology; D005648:Fuel Oils / Q000633:toxicity*; D007636:Keratoacanthoma / Q000139:chemically induced / Q000473:pathology; D051379:Mice; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced* / Q000473:pathology; D010212:Papilloma / Q000139:chemically induced / Q000473:pathology; D010578:Petroleum / Q000633:toxicity*; D011230:Precancerous Conditions / Q000139:chemically induced* / Q000473:pathology; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000473:pathology
chemical_list: D005648:Fuel Oils; D010578:Petroleum
vernacular_title: Kantserogennoe deĭstvie tiazhelogo kataliticheskogo gazoĭlia.