Frequencies of atypical serum cholinesterase in a mixed population of northeastern Brazil.
Frequencies of the CHE1*A allele were estimated in 84 Whites and 772 Negroids from a random sample of Salvador, Bahia. The overall frequency of this gene in Negroids was estimated as 0.842 +/- 0.233%. This indicates that this sample presents around 50 +/- 17% of White admixture and that the estimate of the risk of developing prolonged apnoea in individuals submitted to suxamethonium is around 0.035%, that is about 1 out of 2,900.
D000483:Alleles; D001049:Apnea / Q000139:chemically induced; D044383:Black People; D001938:Brazil; D002802:Cholinesterases / Q000097:blood / Q000172:deficiency / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007199:Indians, South American; D011247:Pregnancy; D012306:Risk; D013390:Succinylcholine / Q000009:adverse effects; D044465:White People
D002802:Cholinesterases; D013390:Succinylcholine