[In vitro biocompatibility: increase in the capacity for adhesion in fibroblasts by materials pretreated with fibronectin].
The Authors expose their observations about the fibroblasts adhesion to materials used as implants in orthopaedic surgery; the first part of the experiment uses normal culture conditions. In the second part the materials have been pre-coated with Fibronectin (FN), a glycoprotein involved in cell-to-substratum adhesion Fibroblasts adhesion increases about 30-40% with pre-coated materials. This observation is important for comprehension of adhesion mechanisms in a multidisciplinary approach to biocompatibility of implant materials.
D000818:Animals; D001672:Biocompatible Materials; D002448:Cell Adhesion / Q000187:drug effects; D006224:Cricetinae; D005347:Fibroblasts / Q000166:cytology* / Q000187:drug effects; D005353:Fibronectins / Q000494:pharmacology*; D014025:Titanium
D001672:Biocompatible Materials; D005353:Fibronectins; D014025:Titanium
Biocompatibilita' in vitro: aumento della capacita' di adesione dei fibroblasti a materiali pretrattati con fibronectina (FN).