[An attempt at demonstrating the participation of autoaggressive processes in the pathogenesis of periodic eye inflammation in horses].
In the studies attempts were to demonstrate the occurrence of immunological reactivity against antigens of the lens and tunica vascularis of the eye in periodical inflammation of eyes in horses. For this purpose antigens from the lens and tunica vascularis of the eye, prepared in our laboratory, were used in the experiments. The reactivity of horses with monthly symptoms of blindness against the above antigens was determined in vivo (skin tests and PCA) and in vitro (ID reaction). The results obtained mainly in skin tests account for its occurrence in some percentage of diseased animals, because in 24 horses examined in this direction six instant reactions and seven semi-retarded reactions against the lens antigens were obtained. Positive reactions against antigens of tunica vascularis were observed in nine and eight cases, respectively. No positive reactions were observed in PCA, whereas in ID reaction specific antibodies against lens antigens were found only in two cases.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000941:Antigens / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology / Q000662:veterinary*; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D010507:Periodicity; D014602:Uvea / Q000276:immunology; D014605:Uveitis / Q000209:etiology / Q000662:veterinary*
D000941:Antigens; D001323:Autoantibodies
Próba wykazania współudziału procesów autoagresyjnych w patogenezie okresowego zapalenia oczu u koni.