title: Estradiol benzoate treatment of an XY gonadal dysgenetic chacma baboon.
abstract: Behavioral studies of an XY gonadal dysgenetic chacma baboon under estradiol benzoate treatment were carried out. The dysgenetic individual and two ovariectomized conspecific control females were given a total of three testing series. The dysgenetic individual showed progressive success in her sexual interactions with her male partners and during her third testing series she was copulated with to ejaculation by five of the eight male partners. This study provides the first supportive evidence from a nonhuman primate for the predicted development of female sexual behavior in a genetic male deprived of testes prior to the sensitive period for sexual differentiation.
mesh_terms: D000818:Animals; D003307:Copulation; D004958:Estradiol / Q000627:therapeutic use*; D005260:Female; D005836:Genitalia, Female / Q000473:pathology; D006059:Gonadal Dysgenesis / Q000188:drug therapy* / Q000473:pathology; D006120:Grooming; D008297:Male; D010215:Papio
chemical_list: D004958:Estradiol