[Scintigraphic diagnosis of multiple pheochromocytomas in childhood with 131I-m-benzylguanidine].
Scintigraphy with 131I-m-BG was used in 4 children with a history of multiple pheochromocytomas in order to localize further catecholamine-producing tumors prior to surgery. We overlook 7 scintigraphies without any side effect. Phenoxybenzamine did not interfere with tracer uptake into tumors. Scintigraphic localization of even smallest extra-adrenal tumors was successful in all cases. In most cases we were dealing with benign pheochromocytomas, but also a ganglioneuroma and metastases of a malignant pheochromocytoma could be revealed. Scintigraphy is a reliable technique for tracing pheochromocytomas and catecholamine-producing ganglioneuromas. It seems to be superior to other non-invasive techniques, furthermore, invasive techniques bearing higher risks may be suspended.
D019797:3-Iodobenzylguanidine; D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D000315:Adrenalectomy; D002395:Catecholamines / Q000652:urine; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005729:Ganglioneuroma / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000601:surgery; D010673:Pheochromocytoma / Q000000981:diagnostic imaging* / Q000601:surgery; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D012086:Reoperation; D013565:Sympatholytics
D002395:Catecholamines; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D013565:Sympatholytics; D019797:3-Iodobenzylguanidine
Szintigraphische Diagnostik multipler Phäochromozytome im Kindesalter mit 131I-m-Benzylguanidin.