Immediate type hypersensitivity in murine coccidiosis.
Subcutaneous injection of soluble merozoite antigen into the footpad of mice previously infected with Eimeria falciformis caused an immediate type hypersensitivity as measured by footpad swelling (FPS). This reaction was first demonstrable ten days after the infection. Maximal values were achieved on day 13, and later on the intensity of FPS decreased. Increase in the dose of oocysts or in the number of infections did not enhance the degree of FPS. The reaction was transferable to normal recipients with immune serum.
D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology; D003048:Coccidiosis / Q000276:immunology*; D004539:Eimeria / Q000276:immunology*; D005260:Female; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D008297:Male; D051379:Mice
D000953:Antigens, Protozoan