Long-term neurological sequelae in achondroplasia.
Two children with achondroplasia and neurologic sequelae secondary to foramen magnum compression were found to have syringomyelia. In one patient, the cyst was associated with a subependymal glioma. These findings suggest that foramen magnum stenosis may lead to irreversible spinal cord damage.
D000130:Achondroplasia / Q000150:complications*; D000293:Adolescent; D003560:Cysts / Q000209:etiology; D005260:Female; D005539:Foramen Magnum / Q000000981:diagnostic imaging; D005910:Glioma / Q000209:etiology; D006801:Humans; D008297:Male; D013117:Spinal Cord Compression / Q000000981:diagnostic imaging / Q000209:etiology*; D013120:Spinal Cord Neoplasms / Q000209:etiology; D013595:Syringomyelia / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed