title: The influence of physical and chemical restraint on the physiology of the chacma baboon (Papio ursinus).
abstract: The chacma baboon (Papio ursinus) is extensively used in South Africa for biomedical research. Being a large primate, it is always necessary to apply some measure of chemical or physical restraint. The physiological effects of placing an animal in a restraint chair are compared with the effects of various chemical agents, such as ketamine, halothane, and ketamine/xylazine combination over 90 min. It was found that ketamine and thiopentone infusion were a satisfactory chemical restraint agent that gave a stable physiological state over 90 min.
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects; D000758:Anesthesia; D000818:Animals; D001784:Blood Gas Analysis; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006400:Hematocrit; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D010215:Papio / Q000502:physiology*; D011188:Potassium / Q000097:blood; D012018:Reflex / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D012149:Restraint, Physical; D012964:Sodium / Q000097:blood; D013874:Thiopental / Q000494:pharmacology; D014991:Xylazine / Q000494:pharmacology
chemical_list: D014991:Xylazine; D007649:Ketamine; D012964:Sodium; D013874:Thiopental; D011188:Potassium; D006221:Halothane