title: [Dietary intake, circulating levels and excretion of carnitine as a function of age in normal children].
abstract: Carnitine metabolism was investigated in 52 normal children aged 1 day to 15 years. Plasma carnitine concentration averaged 83,8 +/- 6,2 (SE) microM, with no age related variation, while both alimentary intake and excretion increased linearly with growth. Carnitine clearance reaches mature levels soon after birth (0.058 +/- 0.007 ml/kg/min). Carnitine intake is significantly higher than excretion only in the first 5 years of life, a fact which suggests a primary role for diet in the supply of carnitine during this period.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002331:Carnitine / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D008297:Male; D012016:Reference Values
chemical_list: D002331:Carnitine
vernacular_title: Apports alimentaires, concentrations circulantes et excrétion de la carnitine en fonction de l'âge chez l'enfant normal.