title: Significance of ST-segment depression in inferior leads in patients with acute anterior infarction.
abstract: Coronary arteriographic findings in patients with acute transmural anterior infarction were studied from 33 patients (30 men and 3 women). Their ages ranged from 28 to 76 years with a mean of 50 years. In 18 patients, ST depression of less than 1 mm in leads II, III and a VF was observed and these contributed to Group A. The remaining 15 patients in whom ST depression in these leads measured 1 mm or more formed Group B. All 33 patients had significant disease of the anterior descending branch of the left coronary artery but in Group A, only 5 (28%) had significant disease of either the right coronary artery (RCA) or the circumflex (CIRC) branch of the left coronary artery (or both) whereas these added lesions were noted in 12 (80%) of the patients in Group B. This was a significant difference (p less than 0.01). The mean peak plasma creatinine phosphokinase (IU/L) in Group B (2475 +/- 1111 S.D.) was greater (p less than 0.005) than in Group A (1147 +/- 998). The mean ejection fraction of 62.6 +/- 14.1% in Group A was higher (p less than 0.001) than that in Group B (40.3 +/- 13%). There was no relation between the duration of ST-segment depression in leads II, III and a VF and the presence of RCA/CIRC stenosis. Also, no correlation was noted between the presence of collateral circulation and the development of ST-segment depression.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000328:Adult; D000368:Aged; D003097:Collateral Circulation; D017023:Coronary Angiography; D003327:Coronary Disease / Q000503:physiopathology; D003402:Creatine Kinase / Q000097:blood; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000503:physiopathology*; D012306:Risk; D013318:Stroke Volume
chemical_list: D003402:Creatine Kinase