Mechanism(s) of calcium antagonists and ischemia.
An overview is provided of the mechanismen of action of the three main calcium antagonists: nifedipine, verapamil and diltiazem, in ischemic heart disease. The thesis is proposed that in individual cases with angina pectoris and ischemic heart disease different and differing actions must be expected with this type of pharmaco-therapy.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000787:Angina Pectoris / Q000188:drug therapy; D000789:Angina, Unstable / Q000188:drug therapy; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000188:drug therapy*; D003329:Coronary Vasospasm / Q000188:drug therapy; D004110:Diltiazem / Q000627:therapeutic use; D004734:Energy Metabolism / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009206:Myocardium / Q000378:metabolism; D009543:Nifedipine / Q000627:therapeutic use; D014700:Verapamil / Q000627:therapeutic use
D002121:Calcium Channel Blockers; D000255:Adenosine Triphosphate; D014700:Verapamil; D004110:Diltiazem; D009543:Nifedipine