Genetic and cytogenetic effects of Fenitrothion.
Male mice (Q strain) were injected intraperitoneally with a high dose (i.e., 1 g/kg) of the organophosphorus insecticide Fenitrothion. No increase in the percentage of chromosome aberrations was observed in bone marrow cells and spermatogonia. A dominant lethal mutation assay did not show any enhancement of fetal mortality before or after implantation.
D000818:Animals; D002869:Chromosome Aberrations / Q000187:drug effects; D003582:Cytogenetics; D005260:Female; D005278:Fenitrothion / Q000008:administration & dosage / Q000633:toxicity*; D005313:Fetal Death / Q000139:chemically induced*; D005333:Fetus / Q000187:drug effects; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D009154:Mutation / Q000187:drug effects; D011247:Pregnancy; D013093:Spermatogonia / Q000187:drug effects
D005278:Fenitrothion