Adrenaline concentration and turnover in the arcuate nucleus and median eminence during the critical period in the rat.
Previous work has shown a relatively high turnover of adrenaline in the mediobasal hypothalamus during the critical period (15.00-17.00 h) of the proestrous rat. We now report that this high level of adrenergic activity can be detected in the median eminence (turnover rate 1.62 +/- 0.36 pg/micrograms protein/h) rather than the arcuate nucleus (turnover rate 0.18 +/- 0.32 pg/micrograms protein/h). In addition the median eminence was isolated as medial and lateral components and determination of catecholamine concentrations revealed a greater proportion of adrenaline (A) (59%) in the lateral median eminence whereas a larger proportion of dopamine (60%) was found in medial median eminence.
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000032:analysis / Q000378:metabolism*; D004298:Dopamine / Q000032:analysis; D004837:Epinephrine / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000378:metabolism; D008473:Median Eminence / Q000032:analysis / Q000378:metabolism*; D009638:Norepinephrine / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains
D006065:Gonadotropins, Pituitary; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine