title: Adhesion, spreading and growth of animal cells on the surface of glass ceramic Ap40--a contribution to the cell compatibility of dental permanent hard tissue implants.
abstract: Cells of different cell lines on the surface of glass ceramic Ap40 responded in the manner of reversible vacuolization in the cytoplasm. Whereas the eluate of bulk glass ceramic did not produce toxic effect on cell populations in vitro, the eluate of pulverized glass ceramic Ap40 caused a toxic reaction, the effect being dependent on concentration and incubation time. Although cell attachment, spreading and proliferation of fibroblast-like and epithel-like cells on glass ceramic surfaces are delayed when compared to glass and polystyrene the cells are adhering to a confluent monolayer.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002448:Cell Adhesion; D002455:Cell Division; D002516:Ceramics / Q000627:therapeutic use*; D003758:Dental Implantation, Endosseous; D005347:Fibroblasts / Q000166:cytology; D008099:Liver / Q000166:cytology
chemical_list: D001672:Biocompatible Materials; C031323:bio-vitroceramic AP40