title: [Myoglobinuria secondary to hypokalemia during prolonged diuretic therapy].
abstract: Myoglobinuria secondary to hypopotassemia was noted in a hypertensive patient treated for a long period with diuretics (chlorthalidone and indapamide). The picture included hypokalemic myopathy, with myoglobinuria, an increase in serum enzymes related by rhabdomyolysis, and flaccid paralysis. In spite of reinstatement management with potassium chloride, hypopotassemia promoted a torsade de pointes, quickly followed by terminal ventricular fibrillation.
mesh_terms: D000368:Aged; D004232:Diuretics / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007008:Hypokalemia / Q000139:chemically induced* / Q000150:complications; D008297:Male; D009212:Myoglobinuria / Q000209:etiology*; D012206:Rhabdomyolysis / Q000209:etiology*; D013610:Tachycardia / Q000209:etiology; D014693:Ventricular Fibrillation / Q000209:etiology
chemical_list: D004232:Diuretics
vernacular_title: Mioglobinuria secondaria ad ipopotassiemia in corso di terapia diuretica protratta.