Clinical pharmacology of hypertension: amelioration of left ventricular performance by treatment with labetalol.
Treatment of 23 hypertensive patients with labetalol at 200 mg twice daily for 3 months resulted in a 15-17% reduction in diastolic and systolic blood pressure, a significant amelioration in the PEP/LVET ratio expressing the haemodynamic performance of the left ventricle, and a significant reduction in its hypertrophy as expressed by the Romhilt-Estes index.
D001794:Blood Pressure / Q000187:drug effects; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007741:Labetalol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D004983:Ethanolamines; D007741:Labetalol