title: The frequency of allergens implicated in bronchial asthma in different areas of Romania.
abstract: The study carried out on 582 asthma patients and 164 healthy controls, ranging in age from 5 to 60 years, dwelling in four different towns ( Sibiu , Mediaş, Baia Mare, Sighetul Marma  tiei ) showed that the most frequently involved antigen in allergic bronchial asthma was house dust (50.3 to 86%), followed by Dermatophagoides pteronissinus and atmospheric fungi, and the most frequently encountered associations were likewise between these allergens, hence the orientation towards a specific hyposensitizing therapy. In these localities with a rich gramineous vegetation there was a high per cent of sensitization to the polen of these plants. Sensitization to woollen hairs has been reported in a high percent in the region of Maramure ş and is linked to its ethnical characteristics. In many cases the patients also exhibited hypersensitiveness to bacteria, associated with environmental allergens, the vicious circle realized by an allergic-infectious mechanism being known. The conclusions of the study on the etiology of bronchial asthma in these geographical areas will be used as a basis for the treatment and its orientation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens; D000818:Animals; D001249:Asthma / Q000453:epidemiology* / Q000276:immunology; D001419:Bacteria; D002648:Child; D002675:Child, Preschool; D004391:Dust; D005241:Feathers; D005260:Female; D005658:Fungi; D006801:Humans; D008297:Male; D008875:Middle Aged; D008925:Mites; D011058:Pollen; D012383:Romania; D014935:Wool
chemical_list: D000485:Allergens; D004391:Dust