Nummular thioridazine retinopathy.
While thioridazine retinopathy has been well described, the features of nummular thioridazine retinopathy, a unique clinical subset, have been documented in only five previously published cases. This report describes the clinical features in an additional three cases. Nummular areas of retinal pigment epithelial atrophy separated by relatively intact pigment epithelium are found in the midretinal periphery, with sparing of central vision. This entity can occur with doses of thioridazine previously considered safe.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012162:Retinal Degeneration / Q000139:chemically induced* / Q000175:diagnosis; D013881:Thioridazine / Q000009:adverse effects*
D013881:Thioridazine