Conformational analysis of 20-keto steroids. Single-crystal X-ray structure analysis of 16 alpha,17-epoxy-4-pregnene-3,20-dione.
The structure of 16 alpha,17-epoxy-4-pregnene-3,20-dione was determined. The 20-carbonyl group eclipses the C(13)-C(17) bond. No direct correlation between the observed structure and its progestational activity could be inferred from our investigation.
D003460:Crystallization; D007664:Ketosteroids / Q000494:pharmacology; D008968:Molecular Conformation; D045167:Progesterone Congeners / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
D007664:Ketosteroids; D045167:Progesterone Congeners