title: Ascorbic acid changes in brain.
abstract: The level of ascorbic acid in the brain of growing rats was not influenced by efforts to accelerate neural activity. Treatments used to depress neural activity included thyroidectomy which produced a 13%-20% loss of ascorbic acid in cortical and cerebellar tissue and diazepam which produced a significant rise in the cerebellum. Ethanol and barbital were without effect.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D001462:Barbital / Q000494:pharmacology; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D002110:Caffeine / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D004777:Environment; D000431:Ethanol / Q000494:pharmacology; D008297:Male; D051381:Rats; D013965:Thyroidectomy
chemical_list: D002110:Caffeine; D000431:Ethanol; D001462:Barbital; D001205:Ascorbic Acid; D003975:Diazepam