[Increase of bile acid reabsorption following total small intestine resection in the rat].
Bile salts undergo an enterohepatic circulation. The relative distribution of labelled cholic acid in portal blood, enterocytes, intestinal contents and feces, following intravenous injection of (carboxylic-14C) cholic acid, can be considered as an indication of the absorptive capacity of the epithelium cells. Seven days after a massive small intestinal resection (60-80 cm), the animal weight and the bile salt absorption were significantly decreased. Nevertheless, thirty days after the operation, weight and radioactivities reached the values found in the controls: in portal and cava blood, liver, intestinal contents and feces. An increase of the absorptive capacity of the intestinal epithelial cells was also observed.
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D019826:Cholic Acid; D002793:Cholic Acids / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000601:surgery*; D007583:Jejunum / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011169:Portal Vein / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D001647:Bile Acids and Salts; D002793:Cholic Acids; D019826:Cholic Acid
Erhöhung der Gallensäureabsorption nach totaler Dünndarmresektion bei der Ratte.