Pigmented basal cell epithelioma arising in the scar of an onchocerciasis nodule.
Pigmented basal cell epithelioma (BCE) arose in the scar of an onchocercoma nodule in a 45-year-old white man. There were extensive fibrosis, inflammation, epidermal hyperplasia, and nests of basal cancer cells. The authors believe that the development of epithelioma in this case was more than a chance occurrence. There is little doubt that the malignant change was subsequent to the scarring-proliferative process of the disease. To the authors' knowledge, this complication has not been reported previously.
D002280:Basal Cell Carcinoma / Q000209:etiology / Q000473:pathology*; D002921:Cicatrix / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009855:Onchocerciasis / Q000150:complications / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012876:Skin Diseases, Parasitic / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology*