title: [Water content of the lungs during 7-day anti-orthostatic hypokinesia].
abstract: The time-course variation of the water content of the lungs of seven male volunteers were examined during 7-day head-down tilt (at -15 degrees). As compared to the horizontal subjects, the tilted subjects showed a significant increase in the water content from 557 +/- 19 ml to 612 +/- +/- 63 ml by the 7th hour of the tilt. Later on the parameter gradually declined and on tilt day 7 almost returned to the pretest level, i.e., 567 +/- 46 ml. This increase in the water content during the first hours of the exposure can be attributed to the hydrostatic factors: higher pulmonary artery pressure and higher cardiac output. The increase in the water content on tilt days 3-7 can be associated with changes in the permeability of lung capillaries, drainage function of the lymphatic system of the lungs, and colloidal-osmotic pressure in the perivascular space of the lungs.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001834:Body Water / Q000378:metabolism*; D002302:Cardiac Output; D006112:Gravitation; D006801:Humans; D006874:Hydrostatic Pressure; D007103:Immobilization; D008168:Lung / Q000098:blood supply / Q000378:metabolism*; D008297:Male; D009997:Osmotic Pressure; D011187:Posture; D011312:Pressure; D011651:Pulmonary Artery / Q000503:physiopathology; D013997:Time Factors
vernacular_title: Soderzhanie vody v legkikh cheloveka vo vremia 7-sutochnoĭ antiortostaticheskoĭ gipokinezii.