[Use of screening for amino acid disorders in the study of the nutrition of the newborn infant: various milk formulas and changes in plasma amino acids].
A sample of 1326 new-born babies has been studied regarding the influence of the milk diet over some plasma-serum amino acids. The Authors have make use of the screening of the congenital errors of the protein metabolism. New-born babies were bled on the fifth or sixth day of life and their blood was analysed at first with the Guthrie test and then with automatic chromatographic determination. New-born babies have been arranged according to their gestational age, birth weight and intrauterine growth. More then 90% of the sample was formed by normal for gestational age new-born babies. We have make use of five different milk formulas: a mixed one (human milk with adapted milks), three powdered milks with three different casein-serum proteins ratio and finally cow's milk with 50% water. The best formula among these ones has been the human milk mixed with adapted milks. The completely artificial formulas, but with casein/serum proteins ratio lower or equal to one, has given rise to a few amino acid alterations, too. On the contrary, the cow's milk mixed with water and the artificial powdered milks with a casein-serum proteins ratio equal to 4.5 shouldn't be utilized in the new-born baby's diet, as they may provoke remarkable alteration in the amino acid metabolism.
D000596:Amino Acids / Q000097:blood*; D000818:Animals; D002417:Cattle; D006801:Humans; D007225:Infant Food / Q000009:adverse effects*; D007228:Infant Nutrition Disorders / Q000097:blood* / Q000209:etiology; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D008715:Methionine / Q000009:adverse effects; D008892:Milk / Q000009:adverse effects; D008895:Milk, Human / Q000378:metabolism; D010649:Phenylalanine / Q000009:adverse effects; D014443:Tyrosine / Q000009:adverse effects
D000596:Amino Acids; D014443:Tyrosine; D010649:Phenylalanine; D008715:Methionine
Utilizzazione dello "screening" per le aminoacidopatie nello studio dell'alimentazione del neonato: formule lattee diverse e variazioni degli aminoacidi plasmatici.