Accommodative range in amblyopic monkeys (Macaca nemestrina).
Three naturally strabismic and two chronic bilaterally atropinized monkeys were tested for spatial contrast sensitivity and range of accommodation. All eyes that showed deficits in contrast sensitivity also showed deficits in accommodation. The strabismic monkeys all showed interocular differences in their CSFs and in their accommodative ranges. The atropine monkeys had no interocular differences on either measure. However, one had depressed contrast sensitivity relative to normal and also showed a reduced accommodative range. A statistically significant correlation was found between the high frequency cutoffs of the CSFs and accommodative ranges. These deficits in accommodative range that accompany contrast sensitivity losses in the monkey are similar to the deficits in accommodative range that accompany amblyopia in humans.
D000065:Accommodation, Ocular / Q000187:drug effects; D000550:Amblyopia / Q000503:physiopathology*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D004195:Disease Models, Animal; D008251:Macaca / Q000502:physiology*; D008254:Macaca nemestrina / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000187:drug effects / Q000502:physiology; D013285:Strabismus / Q000503:physiopathology; D014792:Visual Acuity
D001285:Atropine