Effect of parenteral medications on tcPO2/PaO2 ratios.
We studied the effect of parenteral infusions on transcutaneous arterial oxygen tension ratios in 31 newborn rabbits. Tolazoline and prostaglandin E1 produced a significant fall in skin PO2 values (P less than 0.01). Antibiotics, bicarbonate, diazepam, and dopamine infusions produced no change in PO2 ratios.
D000527:Alprostadil; D000818:Animals; D000831:Animals, Newborn; D004305:Dose-Response Relationship, Drug; D007263:Infusions, Parenteral; D010100:Oxygen / Q000097:blood*; D011458:Prostaglandins E / Q000494:pharmacology; D011817:Rabbits; D012867:Skin / Q000098:blood supply; D014043:Tolazoline / Q000494:pharmacology; D014159:Transducers
D011458:Prostaglandins E; D014043:Tolazoline; D000527:Alprostadil; D010100:Oxygen