[2 cases of anaphylaxis from droperidol].
Following two cases of anaphylactoid reactions during anaesthesia, immunoallergological investigations showed up the responsibility of droperidol, which probably acted by way of an anaphylactic mechanism. In both cases, there were no cardiovascular signs, the main clinical symptom being bronchospasm. The exceptional nature of allergic accidents due to neuroleptic drugs, as opposed to extrapyramidal phenomena, must be underlined. However, these reactions should cast doubts on the safety and usefulness of neuroleptanalgesia.
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced* / Q000276:immunology; D000768:Anesthesia, General / Q000379:methods; D001491:Basophils / Q000276:immunology; D001986:Bronchial Spasm / Q000139:chemically induced; D004329:Droperidol / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male
D004329:Droperidol
Deux cas d'anaphylaxie au dropéridol.