title: [Nature of the coronary vessel response to increased myocardial contractile function].
abstract: Correlation between performance of the myocardium and its blood supply was studied in the dog isolated heart. Accommodation of coronary circulation to changes in myocardiac needs had a complex nature: increasing of cardiac performance within physiological range was accompanied by active changes in coronary resistance, the latter resulting in an increase of the blood flow. A more obvious hyperemic response to transient ischemia in these conditions was attributed to raising of the coronary vessels reactivity. Volume overloading of the heart resulted in lowering of its blood supply and actualization of coronary dilating reserve combined with lowering reactivity of the coronary vessels and with changes in passive component of the coronary resistance due to increasing myocardiac diastolic strain.
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001794:Blood Pressure; D003326:Coronary Circulation; D004285:Dogs; D006439:Hemodynamics; D009200:Myocardial Contraction
vernacular_title: O kharaktere reaktsii venechnykh sosudov pri uvelichenii sokratitel'noĭ funktsii miokardii.