title: Effects of the ovarian and contraceptive cycles on absolute thresholds, auditory fatigue and recovery from temporary threshold shifts at 4 and 6 kHz.
abstract: Absolute thresholds at 4 and 6 kHz were tested in three sessions before and after 20 min of exposure to 105 dB(A) pink noise in 12 young normal-cycling females, 11 young females on oral contraceptives and 8 young men. Women on contraceptives showed lower resting thresholds, larger temporary threshold shift (TTS) and higher recovery rates than normal-cycling females. The analysis of resting thresholds, auditory fatigue and recovery from auditory fatigue did not evidence any sex-linked difference. Significant differences linked to the phases of the menstrual cycle and of the contraceptive cycle were observed during recovery from auditory fatigue at 4 kHz and in resting thresholds at 6 kHz. Application of Kendall's coefficient of concordance confirmed these results. Absolute thresholds were highest at menstruation and lowest in the postovulatory phase in normal-cycling females and in women on oral contraceptives, during the days of pill ingestion. Oral contraception is probably a more important factor of change in hearing performance than the phases of the menstrual cycle.
mesh_terms: D000328:Adult; D001305:Auditory Fatigue / Q000187:drug effects / Q000502:physiology; D001307:Auditory Perception / Q000187:drug effects / Q000502:physiology*; D001309:Auditory Threshold / Q000187:drug effects / Q000502:physiology; D003276:Contraceptives, Oral / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008598:Menstruation; D012737:Sex Factors
chemical_list: D003276:Contraceptives, Oral