Modification of an analgesy meter for paw-pressure antinociceptive testing in neonatal rats.
A modification to a commercially available analgesy meter is described. This modification provides more consistent responses when studying antinociception in neonatal rats using the paw- or tail-pressure tests. The modification is simple and inexpensive and will be especially useful for developmental studies.
D000375:Aging; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000831:Animals, Newborn; D003496:Cyclazocine / Q000031:analogs & derivatives / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000295:instrumentation; D016314:Ethylketocyclazocine / Q000031:analogs & derivatives*; D005528:Foot / Q000502:physiology; D011312:Pressure; D051381:Rats; D013623:Tail / Q000502:physiology
D000700:Analgesics; D016314:Ethylketocyclazocine; C012395:ketazocine; D003496:Cyclazocine