Erythropoietin: a prime regulator of red cell differentiation.
Erythropoietin, a glycoprotein hormone that regulates erythroid differentiation, has been recognized for several decades. Recently, the study of this hormone has increased markedly. It has been purified and partially sequenced. There are several monoclonal and site-specific polyclonal antibodies to it that have revealed important structural information. The gene appears to have been cloned. Current efforts to understand its mode of action will yield answers to questions of importance to both basic scientists and clinicians.
D000818:Animals; D002454:Cell Differentiation; D004912:Erythrocytes / Q000166:cytology*; D004920:Erythropoiesis; D004921:Erythropoietin / Q000502:physiology*; D006801:Humans
D004921:Erythropoietin