title: [Electron microscopic study of cellular differentiation in metastases of cancer of the large intestine in man].
abstract: A comparative ultrastructural study study of the stage and type of differentiation of cancer cells in the primary large intestine human adenocarcinoma and its metastases in the lymph nodes, ovaries, and greater omentum is described. Metastatic cells have been found to retain the features of specific differentiation and be represented by the same groups and main ultrastructural types as in the primary tumor. The main directions of cell differentiation in metastases and in the primary tumor were similar. The role of microenvironment of different organs appeared to be insignificant in the process of cell differentiation in metastases.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology*; D007420:Intestine, Large; D008207:Lymphatic Metastasis; D008854:Microscopy, Electron; D009852:Omentum; D009928:Organ Specificity; D010051:Ovarian Neoplasms / Q000556:secondary*; D010534:Peritoneal Neoplasms / Q000556:secondary*
vernacular_title: Elektronno-mikroskopicheskoe issledovanie differentsirovki kletok raka tolstoĭ kishki cheloveka v metastazakh.