Sub-cellular distribution of copper and caeruloplasmin in chemically induced tumour tissue.
Copper and caeruloplasmin concentrations were determined in the subcellular fraction of tumour tissue from 15 Strain A mice bearing an induced fibrosarcoma. It was observed that copper concentration was higher in the mitochondrial fraction of tumour tissue when compared to that of tissues of similar site from normal controls. However, the caeruloplasmin concentration was lower in the various fractions of tumour tissue when compared to that of normal control tissue.
D000818:Animals; D001564:Benzo(a)pyrene; D002570:Ceruloplasmin / Q000032:analysis*; D003300:Copper / Q000032:analysis*; D005354:Fibrosarcoma / Q000032:analysis / Q000139:chemically induced; D051379:Mice; D008805:Mice, Inbred A; D009374:Neoplasms, Experimental / Q000032:analysis* / Q000139:chemically induced
D001564:Benzo(a)pyrene; D003300:Copper; D002570:Ceruloplasmin