Effects of progesterone on lordotic responses to specific mating stimuli in hamsters.
Mating-induced inhibition of sexual receptivity was examined in ovariectomized, estrogen (E) treated and estrogen plus progesterone (E + P) treated hamsters given 10 min of exposure to male mounting stimulation alone or to mounts, intromissions, and ejaculations at eight hourly intervals. In E + P treated females, no differential effects of exposure to full mating stimulation vs. mounting stimulation alone were observed. In contrast, females given E treatment alone showed a marked differential response. Fully mated, E-treated females showed more lordosis than E-treated females exposed to mounts alone during the initial test. However, total lordosis duration declined precipitiously in the fully mated group by 2 hr and remained significantly below that in other groups during subsequent tests. Levels of receptivity in E-treated females mounted-only remained relatively constant until 8 hr. These results suggest that P reduces the inhibitory effects of vaginocervical cues received during mating without affecting the response to mounting stimulation alone. In addition, vaginocervical stimulation may initially facilitate lordosis in E-treated females.
D000818:Animals; D002584:Cervix Uteri / Q000502:physiology; D006224:Cricetinae; D003463:Cues; D004347:Drug Interactions; D004958:Estradiol / Q000008:administration & dosage; D005260:Female; D008647:Mesocricetus; D011187:Posture; D011374:Progesterone / Q000008:administration & dosage / Q000494:pharmacology*; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D014621:Vagina / Q000502:physiology
D011374:Progesterone; D004958:Estradiol