A male-specific DNA probe detects heterochromatin sequences in a familial Yq- chromosome.
Using a recombinant DNA probe, we have demonstrated the presence of residual 3.4-kilobase (kb) repeat sequences in a family with a Yq- chromosome. The heterochromatin of this Y variant was not readily detectable with conventional chromosome-banding techniques. These data suggest that the breakpoint of the deletion occurs at the heterochromatin region proximal to the euchromatin/heterochromatin junction.
D001483:Base Sequence; D002871:Chromosome Banding; D004247:DNA / Q000235:genetics; D004274:DNA, Recombinant; D006570:Heterochromatin / Q000235:genetics*; D006801:Humans; D008297:Male; D012091:Repetitive Sequences, Nucleic Acid; D014998:Y Chromosome / Q000648:ultrastructure*
D004274:DNA, Recombinant; D006570:Heterochromatin; D004247:DNA