Changes in blood level of catecholamines during arterial blood pressure rise induced with sciatic nerve stimulation.
In experiments on rabbits and dogs it was demonstrated that electrical stimulation of the centripetal fibres of the cut sciatic nerve causing a rise of the arterial blood pressure produced a significant increase in the plasma levels of adrenaline and noradrenaline. This effect was not observed in animals with sympathetic system blockade caused by administration of reserpine. These observations indicate that pressure increase after sciatic nerve stimulation is due to stimulation of the adrenergic system.
D000311:Adrenal Glands / Q000502:physiology / Q000601:surgery; D000315:Adrenalectomy; D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D004558:Electric Stimulation; D004837:Epinephrine / Q000097:blood*; D005260:Female; D008297:Male; D009638:Norepinephrine / Q000097:blood*; D011817:Rabbits; D012110:Reserpine / Q000494:pharmacology; D012584:Sciatic Nerve / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000187:drug effects
D012110:Reserpine; D009638:Norepinephrine; D004837:Epinephrine