title: [Desaturation and nocturnal pulmonary arterial hypertension in C.O.P.D.: effects of oxygen therapy].
abstract: The influence of low flow oxygen on saturation (SaO2) and mean nocturnal pulmonary artery pressure (PAP), was studied in a group of chronic bronchitics suffering from severe airflow obstruction with moderate respiratory failure. 20 patients had oxymetry on ambient air, six underwent a continuous recording of SaO2 and of PAP for 2 nights; the first on ambient air, the second on Oxygen. The six patients showed transitory desaturation, accompanied by instantaneous rise in PAP. The oxygen greatly improved the mean values and maximal variation of SaO2 and PAP, supporting the hypothesis that this treatment is capable of preventing T.A.P., and chronic cor pulmonale in patients whose diurnal blood gas values do not justify continuous oxygen therapy, according to classical criteria.
mesh_terms: D000368:Aged; D001794:Blood Pressure; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology*; D008173:Lung Diseases, Obstructive / Q000503:physiopathology* / Q000628:therapy; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D011651:Pulmonary Artery / Q000503:physiopathology
chemical_list: D010100:Oxygen
vernacular_title: Désaturations et hypertension artérielle pulmonaire nocturnes dans les B.P.C.O.: effet de l'oxygénothérapie.