Vaginal contents show in vitro mutagenic activity.
In Millipore filtrate of some vaginal douching, mutagens were readily detected by means of the Ames Salmonella test. Among 521 subjects, the samples of 76 cases (14.6%) were mutagenic in Salmonella typhimurium TA98 or/and TA100 in the presence or absence of S9 mixture. Dichloromethane and chloroform were found to extract the mutagens satisfactorily.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis*; D007507:Therapeutic Irrigation; D014621:Vagina
D009153:Mutagens