[Balanced hereditary polymorphism and the mortality from cardiovascular diseases in the populations of 17 countries of Europe. II. A component analysis].
Based on the factor analysis (the method of principal components with a varimax rotation of axes), a study was performed on the component structure of interpopulational variations in frequencies of the 50 phenotypes and genes of six polymorphic human systems (ABO, MNSs, Rh, Hp, Gm, HLA). The genetic differences of populations have been found to be related to a small number of independent factors; 7 principal components have extracted 79% of dispersion from the primary data. Five of these components are coupled with mortality from the cardiovascular diseases. The component structure of mortality has specificity in relation to localization of pathological process, age and sex.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001789:Blood Group Antigens / Q000235:genetics; D002318:Cardiovascular Diseases / Q000235:genetics* / Q000401:mortality; D005060:Europe; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D012737:Sex Factors
D001789:Blood Group Antigens; D006680:HLA Antigens
Balansirovannyĭ nasledstvennyĭ polimorfizm i smertnost' ot serdechno-sosudistykh zabolevaniĭ v populiatsiiakh semnadtsati stran Evropy. Soobshchenie II. Komponentnyĭ analiz.