[Tissue proliferation by thrombocyte growth factor].
An essay for determining the growth stimulating activity of human platelets has been established. With the aid of this system a mitogenic factor from crude platelet extract was isolated. Besides a stimulation of DNA-synthesis an enhanced synthesis of collagen and glycosaminoglycans is induced by the platelet growth factor.
D002478:Cells, Cultured; D003094:Collagen / Q000096:biosynthesis; D004247:DNA / Q000096:biosynthesis; D005347:Fibroblasts / Q000187:drug effects; D006025:Glycosaminoglycans / Q000096:biosynthesis; D006801:Humans; D008938:Mitosis / Q000187:drug effects*; D008970:Molecular Weight; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology*
D006025:Glycosaminoglycans; D010982:Platelet-Derived Growth Factor; D003094:Collagen; D004247:DNA
Gewebsproliferation durch Thrombozytenwachstumsfaktor.