title: [Mesopharynx cancers--multifactorial malignancy analysis and therapeutic results].
abstract: Multi-step check method of the diagnosis of malignancy is applied as a synthesis of results of staging, histological classification, histopathological and histochemical grading, to 210 squamous cell carcinomas of the mesopharynx. Among the examined carcinomas, extended tumours were predominant (61%) (T3; T4). No definite relationship between size and prognosis of the tumours was seen. 81% of the carcinomas had regional lymph node metastases. Their rate of cure (41%) was lower than that of the carcinomas without metastases. Histological grading showed that prognosis of the G 1-carcinomas was superior to that of the G 3-carcinomas. Definite histological grading also enabled clear gradation of malignancy of G 2-carcinomas and carcinomas of the lymphatic tissue after histochemical grading. 5-year survival rate of all the therapy results were found after radical resection (50%) and after combined surgical irradiation therapy (63%). The survival rate of the patients with exclusive irradiation therapy was lower (29%).
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008207:Lymphatic Metastasis; D037981:Neck Dissection; D009367:Neoplasm Staging; D010610:Pharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D014062:Tongue Neoplasms / Q000175:diagnosis; D014067:Tonsillar Neoplasms / Q000175:diagnosis
chemical_list: D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase
vernacular_title: Mesopharynxkarzinome--multifaktorielle Malignitätsanalyse und Therapieergebnisse.