[Chronic cerebral injury following radiotherapy for maxillary cancer].
From 1965 to 1982, 195 cases of maxillary cancer receiving more than 30 Gy of radiotherapy and surviving more than 6 months were investigated. Chronic cerebral necrosis following irradiation was found in 5 cases. All of them were irradiated with a total dose of more than 60 Gy. Symptoms caused by radiation injury of the brain were observed after more than 3 years. CT images showed irregular low-density areas in the base of the frontal or the temporal lobe within the irradiated field, and the lesion was enhanced in 16.6% of the patients who were irradiated with more than 60 Gy and survived without local recurrence for more than 3 years. Their symptoms, pathology, treatment, prognosis and procedures to avoid chronic cerebral damage were also discussed.
D000328:Adult; D001921:Brain / Q000528:radiation effects*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000532:radiotherapy*; D009336:Necrosis; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed