title: [Endocrine disorders in "empty" sella turcica].
abstract: The results of endocrine examination of 37 patients with an "empty" sella turcica (22 with primary and 15 with secondary) are discussed. The diagnosis in all cases was verified by the findings of pneumocisternotomography and computer-aided tomography. The trophic function of the hypophysis was mainly studied. It was found that primary "empty" sella turcica mostly occurs in females with a history of many pregnancies. Obesity and disorders of menstrual function were the principal clinical manifestations of endocrine disorders. The inconstantly encountered moderate hyperprolactinemia disappeared after parlodel medication. In secondary "empty" sella turcica hyperprolactinemia was of a more stable character. The trophic function of the hypophysis was reduced in primary "empty" sella turcica as a result of which lesser doses of substitutive hormonal preparations were needed than in secondary "empty" sella turcica. The endocrine disorders in primary "empty" sella turcica were probably of hypothalamic origin, those in a secondary condition were evidently associated with a tumor of the adenohypophysis.
mesh_terms: D000172:Acromegaly / Q000209:etiology; D000328:Adult; D003480:Cushing Syndrome / Q000209:etiology; D004652:Empty Sella Syndrome / Q000150:complications*; D004700:Endocrine System Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology; D008297:Male; D008599:Menstruation Disturbances / Q000209:etiology; D009765:Obesity / Q000209:etiology; D010911:Pituitary Neoplasms / Q000150:complications*; D011388:Prolactin / Q000097:blood; D012735:Sexual Dysfunction, Physiological / Q000209:etiology
chemical_list: D011388:Prolactin
vernacular_title: Endokrinnye narusheniia pri "pustom" turetskom sedle.