title: Information content and one point mutations in DNA.
abstract: It has been suggested recently that data on mutations in human haemoglobin is consistent with the hypothesis that evolution takes place in the direction of increasing informational entropy of DNA. We argue that the mutation data sheds no light on the above hypothesis and show how the data can be understood in terms of random mutation of the bases in DNA.
mesh_terms: D001483:Base Sequence; D005075:Biological Evolution; D003062:Codon; D004247:DNA / Q000235:genetics*; D006454:Hemoglobins / Q000235:genetics; D006801:Humans; D007257:Information Theory; D009154:Mutation; D011336:Probability
chemical_list: D003062:Codon; D006454:Hemoglobins; D004247:DNA