title: Curcuma longa (Linn) drops in corneal wound healing.
abstract: In this study, an attempt has been made to evaluate the cortisone like inhibitory activity on healing of wounds of curcuma longa extracts-aqueous extract (2.8%) and alcoholic extract (1.125%) on the healing of superficial and penetrating corneal wounds in albino rabbits. It was observed that curcuma longa aqueous drops (a) definitely delayed healing of superficial corneal wounds (P less than 0.001), (b) delayed healing of penetrating corneal wounds also and markedly reduced the tensile strength of corneal wounds (P less than 0.02), when comparison was made with placebo and preservative drops.
mesh_terms: D000818:Animals; D003315:Cornea / Q000187:drug effects; D065306:Corneal Injuries; D003348:Cortisone / Q000494:pharmacology; D008515:Medicine, Ayurvedic; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D011817:Rabbits; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D010936:Plant Extracts; D003348:Cortisone