[Effect of acute alcoholic intoxication on the antigenic composition of soluble proteins in the rat brain].
Cross immunoelectrophoresis was used to study antigenic composition of the brain of rats preferring water, or 15% ethanol and of intermediate group animals. The rat brain showed 6 antigens, one of them was found to be neurospecific. The intermediate group animals and those preferring ethanol differed from those preferring water in that they demonstrated two antigens which were found to be neuro-nonspecific. The content of the neurospecific protein S-100 in the cerebellum measured by rocket immunoelectrophoresis was demonstrated to be the same in animals preferring water and ethanol. A single intraperitoneal injection of 25% ethanol (2.5 g/kg) to the intermediate group rats brought about a change in the composition of neuro-nonspecific soluble antigens of the brain.
D000435:Alcoholic Intoxication / Q000276:immunology*; D000818:Animals; D000941:Antigens / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D009419:Nerve Tissue Proteins / Q000276:immunology*; D051381:Rats
D000941:Antigens; D009419:Nerve Tissue Proteins
Vliianie ostroĭ alkogol'noĭ intoksikatsii na antigennyĭ sostav rastvorimykh belkov mozga krys.