title: [Paraneoplastic acrokeratosis].
abstract: The authors discuss the main features of paraneoplastic acro keratosis, a new cutaneous marker of malignancy. Clinically, the condition begins at the extremities of the limbs and spreads upwards secondarily. The eruption is psoriasis-like squamous erythema of the face, hands and feet. Nail changes are present from the onset. These lesions are always associated with a malignant epithelioma, usually of the spino-cellular type localised in the upper respiratory and digestive tracts. Surgical cure of the primary malignant tumour leads to regression of the skin lesions which reappear in case of relapse.
mesh_terms: D004427:Ear Diseases / Q000473:pathology; D004431:Ear, External / Q000473:pathology; D005121:Extremities / Q000473:pathology*; D005148:Facial Dermatoses / Q000473:pathology; D005385:Fingers / Q000473:pathology; D006801:Humans; D007642:Keratosis / Q000473:pathology*; D009260:Nail Diseases / Q000473:pathology; D009668:Nose Diseases / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000473:pathology*; D014034:Toes / Q000473:pathology
vernacular_title: Acrokératose paranéoplasique (A. P. N.).