[Dialysability of aescin].
In experiments with an artificial kidney (Hollow Fiber Kidney) it could be shown that aescin (Reparil) is fully dialysable. The rate of elimination is mainly dependent on the protein binding (ca. 90%) and not on the permeation rate through the membrane. The concentration of aescin in a serum sample decreased exponentially over a 6-h dialysis period to one-third of the initial concentration.
D004058:Diffusion; D004928:Escin / Q000097:blood*; D008567:Membranes, Artificial; D010539:Permeability; D011485:Protein Binding; D006435:Renal Dialysis; D012503:Saponins / Q000097:blood*
D008567:Membranes, Artificial; D012503:Saponins; D004928:Escin
Untersuchungen zur Dialysierbarkeit von Aescin.