Protection against Plasmodium berghei yoelii in chloroquine- and pyrimethamine-treated mice.
The antimalarial drugs chloroquine and pyrimethamine were observed to afford protection to mice treated with these agents. This protection was observed in mice when given a subsequent challenge infection after they had been radically cured of P. b. yoelii infection.
D000818:Animals; D002738:Chloroquine / Q000627:therapeutic use*; D008288:Malaria / Q000276:immunology / Q000517:prevention & control*; D051379:Mice; D010961:Plasmodium; D011739:Pyrimethamine / Q000627:therapeutic use*
D002738:Chloroquine; D011739:Pyrimethamine