Ascorbic acid changes in brain.
The level of ascorbic acid in the brain of growing rats was not influenced by efforts to accelerate neural activity. Treatments used to depress neural activity included thyroidectomy which produced a 13%-20% loss of ascorbic acid in cortical and cerebellar tissue and diazepam which produced a significant rise in the cerebellum. Ethanol and barbital were without effect.
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D001462:Barbital / Q000494:pharmacology; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D002110:Caffeine / Q000494:pharmacology; D003975:Diazepam / Q000494:pharmacology; D004777:Environment; D000431:Ethanol / Q000494:pharmacology; D008297:Male; D051381:Rats; D013965:Thyroidectomy
D002110:Caffeine; D000431:Ethanol; D001462:Barbital; D001205:Ascorbic Acid; D003975:Diazepam