Effect of administration of triiodothyronine on aspartate aminotransferase in pyridoxine-deficient rats.
The state of thyroid function and the effect of triiodothyronine (T3) administration on aspartate aminotransferase isozymes in the livers of rats fed on a diet with or without pyridoxine were examined. Decreased thyroid function in pyridoxine-deficient rats was demonstrated using malic enzyme as a marker of thyroid function in the liver. Administration of T3 increased cytosolic aspartate aminotransferase in the liver of pyridoxine-deficient rats, but not of control rats.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008291:Malate Dehydrogenase / Q000378:metabolism; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000503:physiopathology; D014284:Triiodothyronine / Q000494:pharmacology*; D026681:Vitamin B 6 Deficiency / Q000201:enzymology*
D014284:Triiodothyronine; D008291:Malate Dehydrogenase; D001219:Aspartate Aminotransferases