Plasma and platelet fibrin-stabilizing factor activity in rats intoxicated with phenylmercuric acetate.
Effect of phenylmercuric acetate on the activity of rat plasma and platelet fibrin-stabilizing factor (FSF) was studied. The mercurial was administered to the animals intragastrically in a single dose of 17.9 mg Hg/kg or in repeated doses of 1.79 mg Hg/kg, twice a week for 152 days. The activities of the investigated fibrin-stabilizing factors were significantly increased in the case of intoxicated rats. Such an effect was observed in both types of the exposure.
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D005176:Factor XIII / Q000378:metabolism*; D005260:Female; D010662:Phenylmercuric Acetate / Q000633:toxicity*; D010663:Phenylmercury Compounds / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D013054:Spectrophotometry, Atomic
D010663:Phenylmercury Compounds; D005176:Factor XIII; D010662:Phenylmercuric Acetate