title: [Stress-protective properties of lithium nicotinate--a new derivative of nicotinic acid].
abstract: Experiments were made to study stress-protective properties of a new psychotropic agent lithium nicotinate developed on the basis of natural metabolites. Prophylactic treatment of the drug given in courses entails an increase in the physical endurance and work fitness, improvement of animals' orientation under stress, facilitating the avoidance behavior. These effects were particularly demonstrable in highly emotional animals. In these animals, stress produced a paralyzing action. According to the electro- and ballisto-cardiography, the drug prevented the stress-induced disorders of cardiovascular function.
mesh_terms: D000818:Animals; D004924:Escape Reaction / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D009525:Niacin / Q000627:therapeutic use*; D010807:Physical Endurance / Q000187:drug effects; D051381:Rats; D013315:Stress, Psychological / Q000188:drug therapy*
chemical_list: D009525:Niacin
vernacular_title: Stress-protektornye svoĭstva nikotinata litiia--novogo proizvodnogo nikotinovoĭ kisloty.