title: Faecal chymotrypsin for investigation of exocrine pancreatic function: a comparison of two newly developed tests with the titrimetric method.
abstract: Two newly developed photometric assays for the estimation of faecal chymotrypsin were studied in comparison with the established titrimetric method in 46 patients and 8 healthy volunteers, who had undergone a secretin-pancreozymin test for diagnostic purposes. The correlation between the two photometric methods and the titrimetric method was good (r = 0.90 and r = 0.91), revealing similar diagnostic sensitivity and specificity. As both photometric methods are less time-consuming and may be performed using a standard laboratory equipment, they offer a good alternative to the established titrimetric method for faecal chymotrypsin estimation.
mesh_terms: D002918:Chymotrypsin / Q000032:analysis*; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis; D005243:Feces / Q000032:analysis*; D006801:Humans; D010186:Pancreatic Function Tests / Q000379:methods*; D010195:Pancreatitis / Q000175:diagnosis; D010783:Photometry / Q000379:methods*
chemical_list: D002918:Chymotrypsin