[Indications for the aspirin provocation test in the asthmatic].
Oral provocation tests using aspirin (n = 55), tartrazine (n = 37) and benzoate (n = 28) were performed in 55 asthmatic patients. A positive aspirin provocation test was observed in 15 patients (27%). These patients often had a past history of aspirin intolerance, 53% of them also had nasal polyposis and 5 out of 12 had associated tartrazine intolerance, while 2 out of 8 had associated benzoate intolerance. The authors consider that these features may help the clinician to detect the asthmatic patient at high risk of aspirin intolerance in whom a provocation test should be performed.
D000328:Adult; D001241:Aspirin / Q000009:adverse effects; D001249:Asthma / Q000503:physiopathology*; D001565:Benzoates; D001985:Bronchial Provocation Tests / Q000379:methods*; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D013645:Tartrazine
D001565:Benzoates; D013645:Tartrazine; D001241:Aspirin
Indications du test de provocation à l'aspirine chez l'asthmatique.