title: Low doses of brotizolam and nitrazepam as hypnotics in the elderly.
abstract: 0.125 mg brotizolam and 2.5 mg nitrazepam proved to be equipotent in promoting and maintaining sleep in 29 elderly patients used to long-term hypnotics. These drugs were superior to placebo and they were excellently tolerated. The drugs were administered in a random order, double-blind, for 7 nights each.
mesh_terms: D000368:Aged; D001381:Azepines / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008875:Middle Aged; D009567:Nitrazepam / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*
chemical_list: D001381:Azepines; D006993:Hypnotics and Sedatives; C020960:brotizolam; D009567:Nitrazepam