title: Tissue deposition and clearance of aflatoxins from broiler chickens fed a contaminated diet.
abstract: A study was conducted to determine aflatoxin levels in the tissues of broiler chickens that had been fed a diet containing 2057 micrograms aflatoxin B1 and 1323 micrograms aflatoxin B2/kg for 35 days. Results showed that aflatoxins were deposited in all tissues. The highest levels of aflatoxins were present in the gizzards, livers and kidneys. There was evidence that the high levels of aflatoxins B1 and B2 in the gizzards might have been caused by contamination by the gizzard contents during the slaughtering process. After feeding the aflatoxin-contaminated diet for 35 days, mean values for the combined aflatoxins were less than 3 micrograms/kg of tissue. Four days after withdrawal of the aflatoxin-contaminated ration, there were no detectable amounts of aflatoxins in any of the tissues. The results indicate that broiler chickens rapidly clear aflatoxins from their tissues once they are transferred to an aflatoxin-free diet.
mesh_terms: D000348:Aflatoxins / Q000378:metabolism*; D000821:Animal Feed; D000818:Animals; D002645:Chickens; D005506:Food Contamination; D005895:Gizzard, Avian / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D008460:Meat / Q000032:analysis*; D008657:Metabolic Clearance Rate; D014018:Tissue Distribution
chemical_list: D000348:Aflatoxins