[A case of systemic sclerosis in childhood complicated by severe digital ulcers].
Systemic sclerosis is a diffuse disorder of connective tissue in which there are inflammatory, fibrotic and degenerative changes in the skin and many internal organs. We describe a case of systemic sclerosis type "acrosclerosis" in a six years old child with Raynaud's phenomenon and gastrointestinal involvement. In the course of illness he presented severe digital ulcerations in the hands and in the feet, responsive to a calcium channel blocking agent nifedipine treatment.
D002648:Child; D005385:Fingers; D005533:Foot Dermatoses / Q000150:complications; D006801:Humans; D008297:Male; D009543:Nifedipine / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011928:Raynaud Disease / Q000150:complications* / Q000188:drug therapy; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012883:Skin Ulcer / Q000209:etiology*
D009543:Nifedipine; D011241:Prednisone
Un caso di sclerosi sistemica in età pediatrica complicato da gravi ulcere digitali.