Measurements of local PO2 in the resting skeletal muscles of rats with portocaval anastomosis (PCA) under normoxic conditions.
Direct measurements of local oxygen pressure by means of platinum multiwire electrode were performed in rats to investigate the effect of an end-to-side portocaval shunt procedure on muscle tissue oxygenation. Compared with intact rats and/or sham operated animals, rats with portocaval anastomosis showed a significant increase of muscle tissue oxygenation with nearly bellshaped pO2 histograms. This considerable increase in tissue oxygenation might appear to be due to the well known PCA induced hyperdynamic cardiovascular state.
D000818:Animals; D005260:Female; D006439:Hemodynamics; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D011167:Portacaval Shunt, Surgical; D051381:Rats; D011919:Rats, Inbred Strains