Ultrastructural localization of motilin in endocrine cells of human and dog intestine by the immunogold technique.
Motilin-immunoreactivity has been localized by two electron immunocytochemical techniques, using gold-labelled protein A or IgG as second layer, in a specific type of endocrine cell scattered in the epithelium of human and canine upper small intestine. The motilin (M) cell is characterized by relatively small (180 nm in man; 200 nm in the dog), solid granules with homogeneous core and closely applied membrane, round in man, round to irregularly-shaped in the dog. Perinuclear microfilaments are prominent in human motilin cells.
D000818:Animals; D004285:Dogs; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D006046:Gold; D006651:Histocytochemistry / Q000379:methods*; D006801:Humans; D007120:Immunochemistry; D007074:Immunoglobulin G; D007421:Intestine, Small / Q000032:analysis* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009037:Motilin / Q000276:immunology / Q000378:metabolism*; D013205:Staphylococcal Protein A
D005768:Gastrointestinal Hormones; D007074:Immunoglobulin G; D013205:Staphylococcal Protein A; D009037:Motilin; D006046:Gold