Succinate dehydrogenase activity in relation with cardiac morphology in rats fed low erucic acid rapeseed oil.
The histopathological status and histologically demonstratable succinate dehydrogenase activity were evaluated on contiguous heart sections of rats fed low erucic acid rapeseed oil for 18 weeks. The histologically demonstratable SDH activity was quantified and could be related with the severity of the lesion at the same location. These results were discussed in terms of effects of dietary fat on mitochondria.
D000818:Animals; D001937:Brassica; D004041:Dietary Fats / Q000633:toxicity*; D004883:Erucic Acids / Q000494:pharmacology*; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects; D006651:Histocytochemistry; D009206:Myocardium / Q000201:enzymology* / Q000473:pathology; D009336:Necrosis; D009821:Oils / Q000506:poisoning*; D010938:Plant Oils; D000074262:Rapeseed Oil; D051381:Rats; D011919:Rats, Inbred Strains; D013385:Succinate Dehydrogenase / Q000378:metabolism*
D004041:Dietary Fats; D004883:Erucic Acids; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; D009821:Oils; D010938:Plant Oils; D000074262:Rapeseed Oil; D013385:Succinate Dehydrogenase