title: [The effectiveness and toxicity of a plant secretolytic agent and its component drugs].
abstract: The 50-fold human dosage of a physiomedical drug combination (VG I) (Sinupret) and their components (VG II-VG VI) in equivalent quantity, administered 10 times within 80 h, does not lead to unexpected and undesired effects on the parameters: rate of breathing, pulse rate, red blood count. Quick-%-value and the electrolytes calcium, potassium and sodium. Differences found in single drug groups are considered to be within the range. Concerning secretolytic effects, the drug combination and its components show significant activities performing a production rate of respective levels of 38.7% and 104% above the control groups.
mesh_terms: D000818:Animals; D004573:Electrolytes / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D011817:Rabbits; D012119:Respiration / Q000187:drug effects; D012636:Secretory Rate / Q000187:drug effects*
chemical_list: D004573:Electrolytes; D010936:Plant Extracts
vernacular_title: Zur Wirksamkeit und Toxizität eines pflanzlichen Sekretolytikums und seiner Einzeldrogen.