title: Effect of breathing of a helium-oxygen mixture on the adaptation of the organism to exercise.
abstract: The reported investigations were carried out on 17 healthy men aged 20-27 years subjected to a 15 minute submaximal exercise on an Elema-Schonander cycle ergometer while breathing ambient air or a helium-oxygen mixture (O2 20% and He 80%). During the exercise test the heart rate was recorded from the ECG tracings, with the respiratory rate and respiratory volume, minute ventilation and arterial blood pressure. The concentrations of lactate (LA), pyruvate (PA) and glucose were determined in the serum of venous blood obtained before and 3 minutes after the exercise. Favourable changes of the reaction of the organism to exercise were observed while the subjects breathed the helium-oxygen mixture. The minute ventilation increased owing to increased respiratory volume, and the exercise caused lower rises in LA, PA and the LA/PA ratio. This may suggest a reduction of respiration cost and a decrease of anaerobic metabolism under these conditions.
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects*; D000328:Adult; D000388:Air; D005080:Exercise Test; D006339:Heart Rate; D006371:Helium / Q000494:pharmacology*; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D010100:Oxygen / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D005082:Physical Exertion; D010809:Physical Fitness; D011773:Pyruvates / Q000097:blood; D012119:Respiration; D012146:Rest
chemical_list: D007773:Lactates; D011773:Pyruvates; D006371:Helium; D010100:Oxygen