A note on xenogeneic transfusion of macrophages in experimental septicaemia.
Human peritoneal macrophages (M phi) were given intravenously to normal rabbits and rabbits with Escherichia coli septicaemia. No harmful effects were observed during a period of three months following macrophage transfusions and the septicaemia was eradicated in four of five animals. Thus xenogeneic M phi transfusion is feasible and can combat serious bacterial infections.
D000818:Animals; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000637:transplantation*; D011817:Rabbits; D018805:Sepsis / Q000628:therapy*; D014183:Transplantation, Heterologous