Mitotic variations of the stem cell and its renewal in the Chinese hamster Cricetulus griseus during spermatogenesis: a morphological study.
The stem cell As in the testicular tubule of the Chinese hamster has been identified morphologically in its proliferation and in its transitional variations up to the formation of the primary spermatocyte by means of hypotonics alone. An extensive study of nuclei in their telophase has allowed us to trace the transition of mitosis into meiosis in several stéps. The presence of nuclei in an apparent inactive or "resting" stage strongly supported the renewal of the As stem cell and gave a clue to the presence of an inherent factor in the tubule that regulates the timing of the cycle of the seminiferous epithelium.
D000818:Animals; D002453:Cell Cycle; D002467:Cell Nucleus / Q000648:ultrastructure; D006224:Cricetinae; D003412:Cricetulus; D008297:Male; D008938:Mitosis; D013091:Spermatogenesis; D013234:Stem Cells / Q000648:ultrastructure*; D013737:Testis / Q000166:cytology* / Q000648:ultrastructure