Epiandrosterone- and dehydroepiandrosterone-3 beta-alkanesulfonates as inhibitors of mouse glucose-6-phosphate dehydrogenase activity.
3 beta-Alkanesulfonates of dehydroepiandrosterone, 16 alpha-bromodehydroepiandrosterone, epiandrosterone, and 16 alpha-bromoepiandrosterone were prepared in 54-95% yield via the reaction of long chain alkanesulfonyl chlorides with the corresponding dehydroepiandrosterone, and epiandrosterone analogues. These compounds inhibit mouse glucose-6-phosphate dehydrogenase activity.
D000738:Androsterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005954:Glucosephosphate Dehydrogenase / Q000037:antagonists & inhibitors*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D012867:Skin / Q000201:enzymology
D000738:Androsterone; D005954:Glucosephosphate Dehydrogenase