Spontaneous remission and its significance for trials in primary prevention of hypertension.
The hypothesis that salted food can cause hypertension must be tested prospectively to see if unsalted food protects non-hypertensive persons. The first of two feasibility studies has confirmed that established hypertension can show spontaneous remission on unsalted food. We now report the preliminary findings of a second feasibility study to test whether a clinic for hypertension can attract self-referred non-hypertensive people interested in preventing hypertension by changing their diet. A total of 874 applicants have attended at least one pre-entry visit. We report data from the first 176 participants who completed the feasibility study lasting 12 weeks. Of these 110 were non-hypertensive people and 93 (84.5%) would be prepared to remain on unsalted food for five years.
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D004039:Diet, Sodium-Restricted; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D011322:Primary Prevention; D012075:Remission, Spontaneous; D012964:Sodium / Q000652:urine
D012964:Sodium; D011188:Potassium