Subacute chlordane poisoning.
A 30 year old female was exposed to chlordane through careless and excessive domestic use over a 1 to 4 week period. Early symptoms included circumoral numbness, anorexia, nausea, and fatigue. Myoclonic jerks occurred after a delay of one month. Malaise and anorexia became the dominant symptoms leading to referral at six months. Dysfunctional bleeding was attributed to hepatic enzyme induction by the chlordane and increased metabolism of contraceptive medication. Cholestyramine increased the stool elimination of chlordane.
D000273:Adipose Tissue / Q000378:metabolism; D000328:Adult; D001822:Body Burden; D002706:Chlordan / Q000378:metabolism / Q000506:poisoning*; D002792:Cholestyramine Resin / Q000627:therapeutic use; D005260:Female; D006533:Heptachlor / Q000378:metabolism; D006801:Humans
D002792:Cholestyramine Resin; D002706:Chlordan; D006533:Heptachlor