[Metabolism of choline-containing phospholipids in microsome fractions of the rat brain in acute radiation injury].
A considerable increase in activation of CDP-dependent pathway of the phosphatidylcholine and sphingomyelin synthesis in the microsomal fraction of rat brain grey matter is established one hour after the acute radiation injury. The level of [14C] choline incorporation into phosphatidyl choline is twice as low under these conditions.
D000208:Acute Disease; D000818:Animals; D001921:Brain / Q000378:metabolism*; D003566:Cytidine Diphosphate Choline / Q000378:metabolism; D005260:Female; D008297:Male; D008861:Microsomes / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D013109:Sphingomyelins / Q000378:metabolism*
D010713:Phosphatidylcholines; D013109:Sphingomyelins; D003566:Cytidine Diphosphate Choline
Obmen kholinsoderzhashchikh fosfolipidov fraktsii mikrosom golovnogo mozga krys v usloviiakh ostrogo luchevogo porazheniia.