title: A preliminary study on the in vivo transmission of light through psoriatic plaques.
abstract: The transmission of light through psoriatic plaques has been measured in vivo using a quartz fiber before and after the application of the lipophilic liquid, glycerin. The results indicated a roughly two-fold increase in transmission following the application of glycerin. This was achieved after a period which ranged from 3 to 15 min suggesting a diffusion process. The main problem encountered was bleeding which led to satisfactory data being obtained in only 3 out of 6 patients investigated.
mesh_terms: D000328:Adult; D004817:Epidermis / Q000187:drug effects / Q000528:radiation effects*; D005990:Glycerol / Q000494:pharmacology; D006801:Humans; D008027:Light; D010789:Phototherapy; D011565:Psoriasis / Q000473:pathology / Q000628:therapy*
chemical_list: D005990:Glycerol