Purification of D&C Red No. 33 by preparative high-performance liquid chromatography.
Preparative reversed-phase high-performance liquid chromatography (HPLC) was used to purify a composite sample of D&C Red No. 33. A number of contaminating impurities were isolated from the dye and the purified material was essentially free of residual aromatic amines. A comparison was made between purification by preparative HPLC and recrystallization.
D002851:Chromatography, High Pressure Liquid; D009282:Naphthalenesulfonates / Q000302:isolation & purification*
D009282:Naphthalenesulfonates; C044608:D.C. Red No. 33