Villitis of unknown aetiology: its incidence and significance in placentae from a British population.
A histological study of 1000 randomly selected placentae from women delivered in Manchester, UK, revealed 136 cases of villitis; this is a higher incidence than that recorded in Australia and North America but lower than that noted in South America. There were no obvious clinical differences between mothers whose placentae showed a villitis and those in a control group whose placentae were free of villitis. As in other studies, there was an association between the presence of a villitis, particularly severe villitis, and fetal intrauterine growth retardation. The nature of this association cannot, however, be clarified until the aetiology of villitis is determined.
D000328:Adult; D002824:Chorionic Villi / Q000473:pathology*; D004739:England; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007249:Inflammation / Q000453:epidemiology / Q000209:etiology; D010922:Placenta Diseases / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D011247:Pregnancy; D012494:Sampling Studies