DNA flow cytometry in primary breast carcinoma.
DNA Flow cytometric values were recorded in 66 primary breast carcinomas. Twenty-six tumors were found to be diploid whereas 40 were non-diploid. About 10% of the cells belonged to the S-phase fraction. Non-diploid tumors had significantly larger S-cell fractions (greater than 10%) than diploid ones. High tumor ploidy correlated positively with high clinical stage (stage I versus stage greater than or equal to II) and with high histological grade but was unrelated to estrogen-receptor content and menopausal status.
D001943:Breast Neoplasms / Q000032:analysis / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D009376:Neoplasms, Hormone-Dependent / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis
D004273:DNA, Neoplasm; D011960:Receptors, Estrogen