title: 'Composites'--an aberrant structure of the collagen fibril.
abstract: Ultrastructural investigations are presented concerning the 'composite'-like collagen changes in different kinds of connective tissue diseases. Most impressing findings were observed in processes causing an extensive elastotic degeneration. The morphology of the 'composite'-like collagen changes is described, and some hypotheses are discussed with regard to the pathomechanism of their generation.
mesh_terms: D003094:Collagen / Q000032:analysis*; D003238:Connective Tissue / Q000648:ultrastructure*; D003240:Connective Tissue Diseases / Q000473:pathology*; D003483:Cutis Laxa / Q000473:pathology; D003599:Cytoskeleton / Q000648:ultrastructure; D004535:Ehlers-Danlos Syndrome / Q000473:pathology; D004547:Elastic Tissue / Q000648:ultrastructure; D006801:Humans; D009855:Onchocerciasis / Q000473:pathology; D011561:Pseudoxanthoma Elasticum / Q000473:pathology; D012128:Respiratory Distress Syndrome / Q000473:pathology; D012595:Scleroderma, Systemic / Q000473:pathology; D014648:Varicose Veins / Q000473:pathology
chemical_list: D003094:Collagen