[The effect of dehydration loss of tablet excipients on the energy- distance diagram and on tablet characteristics].
Four tabletting agents of the micro-crystalline cellulose type (Heweten 10, Heweten 12, Heweten 40 and Avicel PH 101) as well as a potato starch lactose granulate had been tabletted on an instrumented slow-motion eccentric press (1 r. p. m.) following storage at different relative humidities. The data resulting from force-punch displacement measurements had been related to the radial steadiness to breakage and the dehydration loss of the relevant agent.
D002482:Cellulose; D002626:Chemistry, Pharmaceutical; D005079:Excipients; D006813:Humidity; D007700:Kinetics; D007785:Lactose; D013314:Stress, Mechanical; D013607:Tablets / Q000032:analysis*
D005079:Excipients; D013607:Tablets; D002482:Cellulose; D007785:Lactose
Untersuchungen zum Einfluss des Trocknungsverlustes von Tablettierhilfsstoffen auf Kraft-Weg-Diagramme und Eigenschaften von Tabletten.