[Effects of interferon on the kinetics of the cell cycle of human lymphoma cultured cells].
The effect of homological and heterological (mice, pigs) interferon on cell cycle kinetics of human lymphoma cell in cultures (lines Molt-4, P3HRj, Namalva, Raji) was studied by the cytofluorimetric method. Different cell populations demonstrated unequal sensitivity to the antiproliferative interferon action. In sensitive cell populations (lines Molt-4, P3HRJ) nonspecific changes were revealed in the cell cycle kinetics. The action of the homological and heterological interferon on the investigated tumour cells was nearly the same.
D000818:Animals; D002453:Cell Cycle / Q000187:drug effects; D002460:Cell Line; D002478:Cells, Cultured; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D007700:Kinetics; D008223:Lymphoma / Q000473:pathology*; D051379:Mice; D013045:Species Specificity; D013552:Swine
D007370:Interferon Type I
Vliianie interferona na kinetiku kletochnogo tsikla kul'tiviruemykh kletok limfom cheloveka.