[Hypotensive effect of nephrectomy in malignant renal hypertension and the function of the remaining kidney at late follow-up].
The long-term results of nephrectomy were evaluated in 27 patients with malignant renal hypertension. The hypotensive effect of nephrectomy, function of the remaining kidney, central hemodynamics, and peripheral blood renin were investigated. It was found that hypertension remitted in subjects with an unaffected remaining kidney which completely compensated for the function of the removed kidney and maintained blood pressure within normal. Nephrectomy performed during malignant arterial hypertension that developed because of unilateral pyelonephritis and unilateral stenosing of the renal artery with a sufficient total renal function before surgery led to a prolonged remission of arterial hypertension and reverse development of the symptoms of its malignancy. Hypertension did not remit during chronic pyelonephritis of a single kidney. Renal function was substantially decreased as compared with the control group.
D000328:Adult; D001794:Blood Pressure; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D006974:Hypertension, Malignant / Q000503:physiopathology* / Q000601:surgery; D006977:Hypertension, Renal / Q000503:physiopathology* / Q000601:surgery; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011704:Pyelonephritis / Q000503:physiopathology / Q000601:surgery; D013997:Time Factors
Gipotenzivnyĭ éffekt nefréktomii pri zlokachestvennoĭ pochechnoĭ gipertonii i funktsional'noe sostoianie ostavsheĭsia pochki v otdalennye sroki nabliudeniia.