Anti-inflammatory action of alpha-1-acid-glycoprotein in urate crystal inflammation.
Injections of alpha-1-acid-glycoprotein along with urate crystals induced less footpad swelling than that caused by injections of urate crystals alone. This anti-inflammatory action of acid-glycoprotein is considered to add further support to the hypothesis that perturbations in acute phase proteins are protective.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D003460:Crystallization; D007249:Inflammation / Q000139:chemically induced; D009961:Orosomucoid / Q000494:pharmacology*; D051381:Rats; D014527:Uric Acid / Q000633:toxicity*
D000893:Anti-Inflammatory Agents; D009961:Orosomucoid; D014527:Uric Acid