title: A multivariate analysis of the risk indicators of reduction limb defects.
abstract: In order to evaluate associations of various selected risk indicators with reduction limb defects, data on 453 cases of reduction limb defects and their time-area matched pair controls from the Finnish Registry of Congenital Malformations was studied. A multivariate analysis of the earlier reported associations was performed. This analysis showed that the following risk indicators were associated with the defects: high birth order, threatened abortion, low placental weight, low birth weight, previous malformations in the family, influenza during early pregnancy, other infectious diseases, and mother's alcohol consumption during pregnancy.
mesh_terms: D000033:Abortion, Threatened / Q000150:complications; D000428:Alcohol Drinking; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017880:Limb Deformities, Congenital; D008423:Maternal Age; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D018566:Pregnancy, High-Risk; D012306:Risk; D012907:Smoking