title: Severe tetanus complicating an open femoral fracture successfully managed using intrathecal human tetanus immunoglobulin and external fixation.
abstract: We report here a case of severe tetanus, complicating a compound fracture of the femur, successfully managed without intensive care facilities, using intravenous sedation and intrathecal Human Tetanus Immunoglobulin (HTI). Substitution of conventional traction (Transtibial Steinman Pin and Thomas Splint) for a Day Frame External Fixation Device (EFD) provided excellent fixation and stability of the fracture in spite of severe tetanic spasms.
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005264:Femoral Fractures / Q000628:therapy*; D005592:Fracture Fixation / Q000379:methods*; D005597:Fractures, Open / Q000628:therapy*; D006801:Humans; D007116:Immunization, Passive / Q000379:methods*; D008297:Male; D009390:Nepal; D013742:Tetanus / Q000628:therapy*; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents