Compound 48/80 is a potent inhibitor of human platelet aggregation antagonizing the calmodulin-dependent platelet reaction in vitro.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D002147:Calmodulin / Q000037:antagonists & inhibitors*; D003094:Collagen / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D010972:Platelet Activating Factor / Q000032:analysis; D010974:Platelet Aggregation / Q000187:drug effects*; D013917:Thrombin / Q000494:pharmacology; D003189:p-Methoxy-N-methylphenethylamine / Q000494:pharmacology*
D002147:Calmodulin; D010972:Platelet Activating Factor; D003189:p-Methoxy-N-methylphenethylamine; D000244:Adenosine Diphosphate; D003094:Collagen; D013917:Thrombin