Decreased biliary excretion of cefamandole after percutaneous biliary decompression in patients with total common bile duct obstruction.
The biliary penetration of cefamandole was studied in six patients with total biliary obstruction before and after placement of a transhepatic bile drainage catheter. Biliary levels of cefamandole remained depressed even when the drug was administered as late as 7 days after decompression of the biliary tract.
D000328:Adult; D001646:Bile / Q000378:metabolism*; D002435:Cefamandole / Q000378:metabolism*; D002779:Cholestasis / Q000378:metabolism*; D003137:Common Bile Duct Diseases / Q000378:metabolism*; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
D002435:Cefamandole