[Effect of the combined use of BCG, PPD, a protein-containing preparation from allogenic tissue and cyclophosphamide in the development of methylcholanthrene-induced tumors].
The organism resistance to the appearance of 20-methylcholanthrene-induced tumours may be enhanced by application of different immunologic factors (BCG, PPD, low-molecular allogenic protein) in combination with a single administration of cyclophosphane (CPh). The positive effect was observed both when CPh was applied prior to the immunologic impact (3 or 7 days before) and after it (3 or 8 days later). In the last case the effect was more stable.
D000818:Animals; D001500:BCG Vaccine / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D008748:Methylcholanthrene; D009124:Muscle Proteins / Q000627:therapeutic use*; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy / Q000628:therapy*; D051381:Rats; D011919:Rats, Inbred Strains; D014373:Tuberculin / Q000627:therapeutic use*
D001500:BCG Vaccine; D009124:Muscle Proteins; D014373:Tuberculin; D008748:Methylcholanthrene; D003520:Cyclophosphamide
Vliianie sochetannogo primeneniia BTsZh, PPD, beloksoderzhashchego preparata iz allogennoĭ tkani i tsiklofosfana na razvitie opukholeĭ, indutsirovannykh metilkholantrenom.