Gastric aspirate L/S ratio and umbilical cord blood total protein as predictors in RDS.
Gastric aspirate L/S ratio and cord blood protein concentration were measured in 150 newborn infants, 33 of whom developed respiratory distress syndrome (RDS). 46.6% of the infants with low gastric aspirate L/S value (less than or equal to 3) and 33.3% of the infants with serum protein of less than or equal to 46 g/l developed RDS. The sensitivity of both parameters was 81.8%. Combination of these two methods yielded a higher predictive value (62.2%) but decreased the sensitivity (69.7%). The patterns of phospholipids reflect lung maturity, but also serum protein levels indicating overall maturity and the osmotic powers of microcirculation may be of diagnostic value in featuring developing RDS.
D001798:Blood Proteins / Q000378:metabolism*; D005312:Fetal Blood / Q000378:metabolism; D005766:Gastrointestinal Contents / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D010713:Phosphatidylcholines / Q000097:blood*; D012127:Respiratory Distress Syndrome, Newborn / Q000097:blood / Q000175:diagnosis*; D012306:Risk; D013109:Sphingomyelins / Q000097:blood*
D001798:Blood Proteins; D010713:Phosphatidylcholines; D013109:Sphingomyelins