Manipulation of the amygdala noradrenergic system impairs extinction of passive avoidance.
In a consolidation paradigm, noradrenergic manipulation of the rat amygdala results in disruption of extinction for passive avoidance. These results are discussed in light of a recent controversy concerning the role of central norepinephrine systems in general extinction behavior. The discussion is cast primarily within the framework of rodent natural life history, the presence of innate behavioral strategies, and the organization of information processing as an integration of experiential attributes.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001931:Brain Mapping; D005108:Extinction, Psychological / Q000502:physiology*; D008297:Male; D009638:Norepinephrine / Q000502:physiology*; D051381:Rats
D009638:Norepinephrine