title: The acute oral and intravenous toxicity of p-aminopropiophenone (PAPP) to laboratory rodents.
abstract: The acute toxicity of p-aminopropiophenone (PAPP) to three species of laboratory animals has been investigated using solutions in dimethylsulphoxide (DMSO) for intravenous and oral (intragastric) administration. In addition, methaemoglobinaemia and Heinz-body haemolytic anaemia are described.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D006168:Guinea Pigs; D006366:Heinz Bodies / Q000187:drug effects; D007275:Injections, Intravenous; D007928:Lethal Dose 50; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced; D051379:Mice; D011427:Propiophenones / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D013997:Time Factors
chemical_list: D011427:Propiophenones; C029564:4-aminopropiophenone