title: Vaginal contents show in vitro mutagenic activity.
abstract: In Millipore filtrate of some vaginal douching, mutagens were readily detected by means of the Ames Salmonella test. Among 521 subjects, the samples of 76 cases (14.6%) were mutagenic in Salmonella typhimurium TA98 or/and TA100 in the presence or absence of S9 mixture. Dichloromethane and chloroform were found to extract the mutagens satisfactorily.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis*; D007507:Therapeutic Irrigation; D014621:Vagina
chemical_list: D009153:Mutagens