title: [Pathogenesis of hemostasis disorders in malignant neoplasms].
abstract: The study was concerned with the effect of thrombin and Xa-factor on the procoagulative and fibrinolytic properties of cultured malignant cells (Hep-2). It was found that active coagulative factors of the blood promote the procoagulative and fibrinolytic potential of neoplasms involving the release of thromboplastic compounds and plasminogen activator into the environment.
mesh_terms: D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D002478:Cells, Cultured; D005170:Factor X / Q000502:physiology; D015951:Factor Xa; D005342:Fibrinolysis; D006801:Humans; D009369:Neoplasms / Q000097:blood*; D010960:Plasminogen Activators / Q000097:blood; D013917:Thrombin / Q000502:physiology
chemical_list: D005170:Factor X; D010960:Plasminogen Activators; D013917:Thrombin; D015951:Factor Xa
vernacular_title: K patogenezu narusheniĭ gemostaza pri zlokachestvennykh novoobrazovaniiakh.