title: Decreased biliary excretion of cefamandole after percutaneous biliary decompression in patients with total common bile duct obstruction.
abstract: The biliary penetration of cefamandole was studied in six patients with total biliary obstruction before and after placement of a transhepatic bile drainage catheter. Biliary levels of cefamandole remained depressed even when the drug was administered as late as 7 days after decompression of the biliary tract.
mesh_terms: D000328:Adult; D001646:Bile / Q000378:metabolism*; D002435:Cefamandole / Q000378:metabolism*; D002779:Cholestasis / Q000378:metabolism*; D003137:Common Bile Duct Diseases / Q000378:metabolism*; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
chemical_list: D002435:Cefamandole