[Ion transport in rat liver mitochondria after freezing and thawing].
Induction of ion transport in the rat liver mitochondria arising after their deep freezing is inhibited effectively by adenosine diphosphate, Mg ions, Ca2+ complexons (EDTA, EGTA) as well as by inhibitors of ATPase (oligomycin and dicyclohexylcarbodiimide) and of electrogenic transport of Ca2+ (ruthenium red). The value of ion flows is determined by adenine nucleotide concentration in the matrix. It is supposed that specific inhibitors of ion electrogenic transport promoting an increase in the transmembrane potential prevent from releasing adenine nucleotides from the mitochondrial matrix.
D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D005615:Freezing; D007425:Intracellular Membranes / Q000378:metabolism; D008297:Male; D008564:Membrane Potentials; D008930:Mitochondria, Liver / Q000378:metabolism*; D010539:Permeability; D051381:Rats; D011919:Rats, Inbred Strains; D014021:Tissue Preservation
D002118:Calcium
Ionnyĭ transport v mitokhondriiakh pecheni krys posle zamorazhivaniia-ottaivaniia.