title: [Karyological characteristics of continuous mouse cell lines infected with the scrapie agent].
abstract: A karyological study of murine cell line L, latently infected with different strains of the scrapie agent (Compton and C-506) showed that the both variants number of chromosomes and the number of Robertson's translocations of chromosomes decrease insignificantly with an increase in the time of subcultivation. The use of the C-method of differential chromosome staining revealed four new analogous chromosomes in both experimental cell lines. This phenomenon is probably specific for this infected cell model.
mesh_terms: D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002871:Chromosome Banding; D007621:Karyotyping; D008677:Metaphase; D051379:Mice; D008807:Mice, Inbred BALB C; D012608:Scrapie / Q000235:genetics*; D012756:Sheep; D014178:Translocation, Genetic
vernacular_title: Kariologicheskaia kharakteristika perevivaemykh liniĭ myshinykh kletok, infitsirovannykh agentom skrepi.