title: [Diminished activity of testosterone-16-alpha hydroxylase in bovine liver microsomes].
abstract: Testosterone 16 alpha hydroxylase is a liver microsome-bound, dependent monooxygenase cytochrome P 450. In contrast with the rat and the mouse, 16 alpha hydroxylase activity appeared to be very low in the bovine liver and was very similar to the human values. By contrast, the level of cytochrome P 450 in the liver protein is very similar in all species. In the bovine species, the activity of the enzyme was 15.14 +/- 7.05 pmol/(min x mg of microsomal protein) and the level of cytochrome P 450 was 0.845 +/- 0.196 nmol/mg of microsomal protein.
mesh_terms: D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases; D002417:Cattle / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D039181:Steroid 16-alpha-Hydroxylase; D013250:Steroid Hydroxylases / Q000378:metabolism*
chemical_list: D003577:Cytochrome P-450 Enzyme System; D013250:Steroid Hydroxylases; D001189:Aryl Hydrocarbon Hydroxylases; D039181:Steroid 16-alpha-Hydroxylase; C022724:testosterone 7-alpha-hydroxylase, hamster
vernacular_title: Faible activité de la testostérone 16 alpha hydroxylase des microsomes hépatiques bovins.