An unusual repetitive structure of caerulein mRNA from the skin of Xenopus laevis.
The nucleotide sequence of a 784-bp segment of cloned caerulein mRNA obtained from the skin of Xenopus laevis was determined. It codes for five heterogeneous procaerulein peptides interspersed with three 147-bp intercaerulein segments (ICS). The ICSs contain six inverted repeats and five eukaryotic enhancer-like sequences. Evidence for the presence of multiple forms of caerulein mRNA is presented.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002108:Ceruletide / Q000235:genetics*; D004274:DNA, Recombinant; D004742:Enhancer Elements, Genetic; D011498:Protein Precursors / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D012867:Skin / Q000032:analysis; D014981:Xenopus / Q000235:genetics*
D004274:DNA, Recombinant; D011498:Protein Precursors; D012333:RNA, Messenger; D002108:Ceruletide