Potassium wasting and other renal tubular defects with rifampin nephrotoxicity.
Interstitial nephritis consequent to rifampin was associated with potassium wasting, an acidifying defect, high fractional uric acid excretion, and glucosuria, indicating a multiplicity of renal tubular transport abnormalities. Enlarged kidneys on sonogram and proteinuria were also observed.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D006801:Humans; D007008:Hypokalemia / Q000209:etiology*; D007684:Kidney Tubules / Q000473:pathology; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D011188:Potassium / Q000378:metabolism; D012293:Rifampin / Q000009:adverse effects*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy; D014527:Uric Acid / Q000378:metabolism
D000900:Anti-Bacterial Agents; D014527:Uric Acid; D011188:Potassium; D012293:Rifampin