Failure of thromboxane synthetase inhibition to improve exercise tolerance in patients with stable angina pectoris.
We report the results of a double-blind study of dazoxiben in which treatment was continued for 3 weeks in patients with angiographically proven coronary artery disease who were receiving no other antiplatelet drugs.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects; D004311:Double-Blind Method; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D010101:Oxygen Consumption / Q000187:drug effects; D005082:Physical Exertion / Q000187:drug effects; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*
D007093:Imidazoles; C029166:dazoxiben; D010088:Oxidoreductases; D013930:Thromboxane-A Synthase