title: [Are retinoids of value in bladder tumors? Pharmacological study and literature review].
abstract: Retinoids are vitamin A derivatives with a modified final radical, lateral chain or initial cycle. Their action on malignant cells is not fully known, but probably consists of the control of cell growth and differentiation. Experiments suggest that retinoids are non-toxic, and that they are far more effective against severe lesions than against dysplasia. Their effect is dose-related and dependent on the type of carcinogen.
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D065108:Ornithine Decarboxylase Inhibitors; D012176:Retinoids / Q000494:pharmacology / Q000627:therapeutic use*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
chemical_list: D065108:Ornithine Decarboxylase Inhibitors; D012176:Retinoids
vernacular_title: Les rétinoïdes ont-ils un intérêt dans les tumeurs vésicales? Etude pharmacologique et revue de la littérature.