Rapid determination of 5-fluorocytosine levels in blood.
Levels of 5-fluorocytosine in blood were rapidly calculated by determining the amount of competition in the creatinine iminohydrolase (creatinine deiminase; EC 3.5.4.21) assay for creatinine with the Kodak Ektachem system (Eastman Kodak Co., Rochester, N.Y.). The correlation with bioassay values was extremely high (r = 0.982). Standards and samples were highly stable over time.
D000619:Aminohydrolases; D001681:Biological Assay; D003404:Creatinine / Q000097:blood; D003596:Cytosine / Q000031:analogs & derivatives*; D005437:Flucytosine / Q000097:blood*; D006801:Humans
D003596:Cytosine; D003404:Creatinine; D005437:Flucytosine; D000619:Aminohydrolases; C023157:creatinine deiminase