[Biocompatibility of implants with and without fluorohydrocarbon glow-discharge polymer coating. 3. Mathematical models of the subsiding processes of the tissue reaction].
The subsidence process of the tissue reaction was estimated by the thickness of the fibrous capsule as well as different histologic characteristics in dependence on the period after the implantation of 4 several implant materials. This subsidence process was fitted mathematically by an exponential function respectively a power function by means of the regression analysis. The power function described best the experimentally found curve. The correspondence, on principle, of the subsidence process of the fibrous capsula thickness on the one hand and the 9 histologic characteristics on the other hand could be proved. A standard valuation for subcutaneous tests is demanded which include the designation of the thickness of the fibrous capsula as well as characteristic cell type frequencies as histologic characteristics.
D000818:Animals; D001672:Biocompatible Materials; D005453:Fluorescence; D006168:Guinea Pigs; D006845:Hydrocarbons, Fluorinated / Q000633:toxicity*; D007249:Inflammation / Q000503:physiopathology; D008433:Mathematics; D008954:Models, Biological; D011108:Polymers / Q000633:toxicity*; D019736:Prostheses and Implants; D012867:Skin / Q000187:drug effects; D012882:Skin Tests; D013329:Structure-Activity Relationship
D001672:Biocompatible Materials; D006845:Hydrocarbons, Fluorinated; D011108:Polymers
Zur Biokompatibilität von Implantaten mit und ohne Fluorkohlenwasserstoff-Glimmpolymerbeschichtung. 3. Mathematische Modellierung des Abklingprozesses der Bindegewebsreaktion.