Injectable ibuprofen: preliminary evaluation of its ability to decrease peritendinous adhesions.
Peritendinous adhesions continue to limit the full return of hand function following flexor tendon injury and repair. Pilot studies in rabbits demonstrated the ability of ibuprofen (Motrin) to reduce intra-abdominal adhesions. In this study, ibuprofen injected at the site of flexor tendon repair significantly reduced the restrictive effects of peritendinous adhesions in primates.
D000818:Animals; D002921:Cicatrix / Q000517:prevention & control*; D006230:Hand Injuries / Q000188:drug therapy* / Q000601:surgery; D007052:Ibuprofen / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D007267:Injections; D008252:Macaca fascicularis; D013708:Tendon Injuries / Q000188:drug therapy* / Q000601:surgery; D000267:Tissue Adhesions / Q000188:drug therapy
D007052:Ibuprofen