Effect of raised portal venous pressure on blood pressure, urine output and body fluids.
Acute rise of portal venous pressure resulted in a fall of blood pressure and subsequent anuria which could be either due to the state of shock or may be reflex in origin. There also occurred an increase in extra-cellular fluid volume with an initial increase in both plasma volume and interstitial fluid volume. Subsequently the extra-cellular fluid volume remained at a high steady value whereas the plasma volume increased at the expense of interstitial fluid volume which decreased. It is further postulated that the rise of extra-cellular fluid volume is due to the shift of fluid from intra-cellular compartment of the extra-cellular compartment, as a defence mechanism to combat the state of shock.
D000818:Animals; D001794:Blood Pressure; D001826:Body Fluids / Q000502:physiology*; D004285:Dogs; D005260:Female; D007668:Kidney / Q000502:physiology*; D008297:Male; D011169:Portal Vein / Q000502:physiology*; D014556:Urine; D014690:Venous Pressure