[Potentials and conditions for the reversion of pathogenic properties of the causative agent of cholera in an experiment].
The passage of V. cholerae noncholerigenic strains and their mutants, both in vitro and in vivo, has demonstrated that strains in which one of such properties as mobility, viability, adhesive, lecithinase and neuraminidase activities, is sharply decreased or lost, are still capable of reversion to cholerigenic forms. V. cholerae strains which have lost two or more of these properties, as well as strains having stable hemolytic activity determined by Greig's test, seem to be incapable of such reversion.
D000818:Animals; D000833:Animals, Suckling; D003470:Culture Media / Q000378:metabolism; D014644:Genetic Variation; D006461:Hemolysis; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000382:microbiology; D051379:Mice; D009154:Mutation; D009439:Neuraminidase / Q000378:metabolism; D010740:Phospholipases / Q000378:metabolism; D011817:Rabbits; D014734:Vibrio cholerae / Q000201:enzymology / Q000254:growth & development / Q000472:pathogenicity*; D014774:Virulence
D003470:Culture Media; D010740:Phospholipases; D009439:Neuraminidase
Vozmozhnosti i usloviia reversii patogennykh svoĭstv vozbuditelia kholery v éksperimente.