title: Vitamin A and biochemical development. II. Effect of postnatal excess vitamin-A administration on the activity of pyridine nucleotide-linked dehydrogenases.
abstract: The effect of excess vitamin A, (1,000 IU) administration to rat pups on the 4th, 6th, 8th and 10th days of age was studied on the activities of combined HMP dehydrogenases, malic enzyme and isocitrate dehydrogenase on the 11th, 17th and 23rd days of age. The developmental pattern and the effect of vitamin-A administration differs from enzyme to enzyme and organ to organ.
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D005260:Female; D006321:Heart / Q000187:drug effects; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008168:Lung / Q000187:drug effects / Q000201:enzymology; D008291:Malate Dehydrogenase / Q000378:metabolism; D009206:Myocardium / Q000201:enzymology; D009252:NADPH Dehydrogenase / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism*; D010427:Pentose Phosphate Pathway; D051381:Rats; D011919:Rats, Inbred Strains; D014801:Vitamin A / Q000494:pharmacology*
chemical_list: D014801:Vitamin A; D010088:Oxidoreductases; D008291:Malate Dehydrogenase; D007521:Isocitrate Dehydrogenase; D009252:NADPH Dehydrogenase