The influence of physical and chemical restraint on the physiology of the chacma baboon (Papio ursinus).
The chacma baboon (Papio ursinus) is extensively used in South Africa for biomedical research. Being a large primate, it is always necessary to apply some measure of chemical or physical restraint. The physiological effects of placing an animal in a restraint chair are compared with the effects of various chemical agents, such as ketamine, halothane, and ketamine/xylazine combination over 90 min. It was found that ketamine and thiopentone infusion were a satisfactory chemical restraint agent that gave a stable physiological state over 90 min.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000758:Anesthesia; D000818:Animals; D001784:Blood Gas Analysis; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006400:Hematocrit; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D010215:Papio / Q000502:physiology*; D011188:Potassium / Q000097:blood; D012018:Reflex / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D012149:Restraint, Physical; D012964:Sodium / Q000097:blood; D013874:Thiopental / Q000494:pharmacology; D014991:Xylazine / Q000494:pharmacology
D014991:Xylazine; D007649:Ketamine; D012964:Sodium; D013874:Thiopental; D011188:Potassium; D006221:Halothane