title: [Tolerance to veralipride administered for an extended time].
abstract: The author has studied the effects of the long-term administration (mean: 8 months) of veralipride in 12 menopausal women (7 naturally, 5 surgically). Veralipride was administered in a dose of one capsule daily, 20 days per month. Results were excellent in 4 cases, good in 6 cases and average in 2. In 9 cases out of 12, menopausal flushing totally disappeared. The study demonstrates good clinical tolerance to the drug and no repercussion on biological parameters other than a significant rise in prolactin levels.
mesh_terms: D004361:Drug Tolerance; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008593:Menopause / Q000187:drug effects*; D008875:Middle Aged; D011388:Prolactin / Q000097:blood; D011602:Psychophysiologic Disorders / Q000188:drug therapy*; D013469:Sulpiride / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D013997:Time Factors
chemical_list: D013469:Sulpiride; D011388:Prolactin; C027429:veralipride; D006854:Hydrocortisone
vernacular_title: Etude de la tolérance du véralipride administré de façon prolongée.