Liquid membrane phenomenon in diuretics.
Surface activity and critical micelle concentrations are reported for two diuretic drugs, furosemide and triamterene. The drugs generate a liquid membrane on a supporting membrane. Transport of chloride, sodium, and potassium ions through the liquid membranes generated by the drugs was studied. The data suggest that the phenomenon of liquid membrane formation may contribute to the diuretic action.
D004232:Diuretics / Q000032:analysis*; D005665:Furosemide / Q000032:analysis; D008567:Membranes, Artificial; D008823:Micelles; D010539:Permeability
D004232:Diuretics; D008567:Membranes, Artificial; D008823:Micelles; D005665:Furosemide