[Cellular and humoral immunity factors in salmonellosis and food toxinfections].
The present work deals with the state of cell-mediated and humoral immunity in 129 patients with salmonellosis and 185 patients with alimentary toxicoinfections, determined from the data obtained in the leukocyte migration inhibition (LMI) test and the passive hemagglutination (PHA) test with cysteine, at different stages of the disease and depending on the severity of the infectious process. The results of these investigations showed that in adult salmonellosis patients the specific reaction of T- and B-lymphocytes developed as secondary immune response. The results of the LMI test proved to be unrelated to the severity of the infectious process, while antibody formation was found to be most intensive in the acute course of the disease. The investigations also revealed that the activity of reaction in the LMI est did not depend on the presence of humoral antibodies. In the patients with alimentary toxicoinfections changes in the results of the LMI test and the PHA test with cysteine showed the same regularities as in the salmonellosis patients. This permitted the authors to suggest that diseases of Salmonella etiology prevailed in the former group.
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D002464:Cell Migration Inhibition; D003545:Cysteine; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012475:Salmonella / Q000276:immunology; D012478:Salmonella Food Poisoning / Q000276:immunology*; D012480:Salmonella Infections / Q000276:immunology*
D000907:Antibodies, Bacterial; D003545:Cysteine
Sostoianie nekotorykh faktoorov kletochnogo i gumoral'nogo immuniteta pri sal'monelleze i pishchevykh toksikoinfektsiiakh.