[Comparative effectiveness of finoptin, corinfar and their combination in patients with angina pectoris].
In a series of 20 patients with stable angina of effort, the authors, using repeated exercise tests, attempted to select the effective antianginal doses of verapamil (finoptine) and nifedipine (corinfar) and to assess the effectiveness of their combination in lower doses following a single administration of the drugs. Verapamil was found to be a more effective antianginal drug than nifedipine. The antianginal effect of both drugs was comparatively short-term. A combined use of verapamil and nifedipine in low doses was demonstrated to be a good alternative choice in cases of side effects arising upon the separate employment of high doses of the drugs.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use*; D014700:Verapamil / Q000008:administration & dosage / Q000627:therapeutic use*
D014700:Verapamil; D009543:Nifedipine
Sravnitel'naia éffektivnost' finoptina, korinfara i ikh sochetaniia ubol'nykh so stenokardieĭ.