[Plasma and saliva DST (dexamethasone suppression test) in depression. Clinical applications and kinetic approach].
Both plasmatic and salivary DST were simultaneously performed on a sample of 37 patients with a diagnosis of major depressive disorder (DMS III criteria): 22 primary depressions and 15 secondary depressions. Salivary DST showed a similar specificity but a decreased sensitivity in comparison with plasmatic DST. Essentially, the simultaneous use of both tests resulted in a better specificity for primary depression.
D000328:Adult; D003866:Depressive Disorder / Q000175:diagnosis* / Q000378:metabolism; D003907:Dexamethasone; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010912:Pituitary-Adrenal Function Tests / Q000379:methods*; D011863:Radioimmunoassay; D012463:Saliva / Q000378:metabolism*
D003907:Dexamethasone; D006854:Hydrocortisone
DST plasmatique et salivaire dans la dépression. Applications cliniques et approche cinétique.