[Effect of microiontophoretic exposure to H+ and HCO3(-) on the bioelectric activity and redox status of the neurons in bulbar chemosensitive areas].
Microiontophoretic application of H+ and H+ + HCO-3 to optically monitored multipolar neurons in the caudal and intermediate bulbar chemosensitive areas increased their firing rate and induced discharges in previously "silent" neurons. A reverse effect occurred in some cases. An interrelationship was revealed between changes of the neurons redox-state and the parameters of their spike activity.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology*; D002415:Cats; D002628:Chemoreceptor Cells / Q000187:drug effects* / Q000378:metabolism; D006859:Hydrogen / Q000494:pharmacology*; D007478:Iontophoresis; D008526:Medulla Oblongata / Q000187:drug effects* / Q000378:metabolism; D008564:Membrane Potentials / Q000187:drug effects; D008839:Microelectrodes; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects
D001639:Bicarbonates; D006859:Hydrogen
Vliianie mikroionoforeticheskogo vozdeĭstviia H+ i HCO3(-) na bioélektricheskuiu aktivnost' i redoks-sostoianie neĭronov bul'barnykh khemochuvstvitel'nykh zon.