Uptake of colloids by bone is dependent on bone blood flow.
In rat the uptake of colloids by the femur and tibia is dependent on bone plasma flow even if other factors modulate the relationship. We warn Nuclear Medicine scientists against the use of colloid uptake measurement as a marker of the bone macrophagic population, especially in situations associated with modified bone plasma flow.
D000818:Animals; D001842:Bone and Bones / Q000098:blood supply / Q000378:metabolism*; D008863:Microspheres; D051381:Rats; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow; D013667:Technetium; D017556:Technetium Compounds; D014002:Tin Fluorides
D017556:Technetium Compounds; D014002:Tin Fluorides; C036078:technetium Tc 99m tin fluoride colloid; D013667:Technetium