[Nuclear medicine diagnosis of pulmonary capillary protein leakage].
Pulmonary extravascular albumin extravasation in patients with adult respiratory distress syndrome can be quantified with radionuclide techniques. While imaging procedures with a computerized gamma camera will allow reproducible ROIs, this will be the main limitation in nonimaging measurements with small scintillation probes. Repeated positioning by one operator results in a mean spatial variation of position of about 2 cm and a variation in count rate of 25%. For the estimation of PCPL the small probes must be positioned under scintigraphic control. Under these conditions the results of both techniques are identical. The upper limit of normal was estimated to be 1 x E-5/sec. The standard deviation of abnormal measurements was about 10%. The pulmonary capillary protein leakage can be quantified by radionuclide techniques with good accuracy, using the combination of imaging and nonimaging techniques.
D001798:Blood Proteins / Q000378:metabolism*; D006801:Humans; D011652:Pulmonary Circulation; D011877:Radionuclide Imaging; D012128:Respiratory Distress Syndrome / Q000000981:diagnostic imaging*; D013668:Technetium Tc 99m Aggregated Albumin; D014947:Wounds and Injuries / Q000150:complications
D001798:Blood Proteins; D013668:Technetium Tc 99m Aggregated Albumin
Nuklearmedizinische Diagnostik des "Pulmonary Capillary Protein Leakage".