title: [Pneumatic cold cap for the prevention of doxorubicin-induced alopecia].
abstract: Since 1973 several methods were described in the literature to prevent Doxorubicin induced alopecia. Besides the application of pressure scalp hypothermia gained increasing importance. Various modifications of scalp hypothermia were developed which are expensive and not easy in the handling so far. We are introducing a method in which a pneumatic cap is used for the application of ice on the scalp. With this method which is comperatively cheap and easy to be handled we got a protective effect against doxorubicin-induced hair loss which was at least as efficient as the current results with other methods referred in the literature.
mesh_terms: D000505:Alopecia / Q000139:chemically induced* / Q000517:prevention & control; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006260:Head Protective Devices; D006801:Humans; D007036:Hypothermia, Induced / Q000295:instrumentation*; D011482:Protective Devices; D012535:Scalp
chemical_list: D004317:Doxorubicin; D003520:Cyclophosphamide
vernacular_title: Pneumatische Kältehaube gegen Doxorubicin-bedingte Alopezie.