title: [Clinical and cisternographic differential diagnosis between presenile dementia and Hakim syndrome].
abstract: The authors compared with regard clinical and the radionuclide cisternography examination 27 patients with Hakim-Syndrome and 11 with Alzheimer-Disease. In all cases, dementia was a stable symptom. Patients with Hakim-Syndrome have an early gait disturbance, ataxia and epileptic seizures. Only in case of patients with Alzheimer-Disease we found aphasia, apraxia and psychotic disorders. 24 hours after the injection radionuclide cisternography showed ventricular retention and absence of parasagital accumulation only in patients with Hakim-Syndrome. Lighter changes (mixed cisternographic pattern) were found in patients with Alzheimer-Disease as well.
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis*; D001284:Atrophy; D002540:Cerebral Cortex / Q000473:pathology; D003704:Dementia / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis*; D006850:Hydrocephalus, Normal Pressure / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011011:Pneumoencephalography
vernacular_title: Klinische und zisternographische Differentialdiagnose zwischen präseniler Demenz und Hakim-Syndrom.