Reduction of serum and testicular sialic acid by melatonin-free pineal extract in rats.
The effect of a melatonin-free pineal extract on sialic acid in the rat was studied. Administration of 2 ml extract/day/animal for 3 and 12 days induced the following effects: a) a statistically significant decrease in testicular concentration and content of sialic acid after 3 days (by 14 and 16% respectively) and b) a statistically significant decrease both in testicular concentration and content and serum level of sialic acid after 12 days (by 13, 12 and 9% respectively). The involvement of the pineal extract in the synthesis and secretion of testicular sialic acid is discussed.
D000818:Animals; D008297:Male; D010870:Pineal Gland; D051381:Rats; D012794:Sialic Acids / Q000097:blood / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*; D014020:Tissue Extracts / Q000494:pharmacology*
D012794:Sialic Acids; D014020:Tissue Extracts