[Decrease in transcortin binding activity in depression].
In a preliminary study, Cortico-Binding Globuline (CBG) has been determined in 10 depressed major inpatients (DSM3) and compared with healthy volunteers. A clear cut fall of binding activity of transcortin is reported in depressed patients associated with an increase of total and free plasmatic cortisol.
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000097:blood*; D003866:Depressive Disorder / Q000097:blood*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D014156:Transcortin / Q000097:blood*
D014156:Transcortin; D006854:Hydrocortisone
Diminution de l'activité liante de la transcortine (CBG) dans la dépression.