Circulating immune complexes, immunoglobulins, complement, antibodies to dietary antigens, cholesterol and lipoproteins levels in patients with occlusive coronary lesions.
The presence of circulating immune complexes, serum immunoglobulins, C3 (the third component of complement), antibodies to alpha-lactalbumin, beta-lactoglobulin and bovine serum albumin was studied in 39 patients subjected to coronary arteriography. Total serum cholesterol and triglycerides and cholesterol in VLDL, LDL and HDL were also estimated. The results obtained in the group of patients found with occlusive lesions were compared with those found in the group without lesions. With one of the five assays used for the detection of immune complexes, higher and significant levels were found in the group with lesions. A negative and significant correlation was found between the number of vessels with lesions and the levels of serum C3.
D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D000936:Antigen-Antibody Complex / Q000378:metabolism*; D000941:Antigens / Q000276:immunology*; D002784:Cholesterol / Q000097:blood*; D003176:Complement C3 / Q000378:metabolism*; D003327:Coronary Disease / Q000276:immunology*; D005260:Female; D005502:Food; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007768:Lactalbumin / Q000276:immunology; D007782:Lactoglobulins / Q000276:immunology; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012710:Serum Albumin, Bovine / Q000276:immunology
D000906:Antibodies; D000936:Antigen-Antibody Complex; D000941:Antigens; D003176:Complement C3; D007136:Immunoglobulins; D007782:Lactoglobulins; D008074:Lipoproteins; D012710:Serum Albumin, Bovine; D007768:Lactalbumin; D002784:Cholesterol