[The heterozygote beta-thalassemic patient with regard to radiological hazards].
Since anaemia of varying degree is a quite common finding in heterozygous beta-thalassaemia, a research was done to see if beta-thalassaemia heterozygotes occupationally exposed to long-term continuous external radiation should be more susceptible to haematopoietic damage than non thalassaemic subjects. We examined peripheral haematological findings of 20 beta-thalassaemia heterozygotes previously exposed to a mean of 10.7 mSv, compared with 22 non thalassaemic subjects exposed to 6 mSv, and with 50 not exposed beta-thalassaemia heterozygotes. The obtained results suggest that whole-body external irradiation--with the mean doses reported--does not cause noteworthy changes in beta-thalassaemia heterozygotes.
D000293:Adolescent; D000328:Adult; D001772:Blood Cell Count; D004781:Environmental Exposure; D005260:Female; D006400:Hematocrit; D006452:Hemoglobinometry; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology*; D011829:Radiation Dosage; D011830:Radiation Effects; D011839:Radiation, Ionizing; D012306:Risk; D013789:Thalassemia / Q000097:blood / Q000150:complications* / Q000235:genetics
Il beta-talassemico eterozigote di fronte al rischio radiologico.