Spherulite crystals in synovial tissue of a patient with recurrent monoarthritis.
Frozen, unstained sections of synovial tissue of a 38-year-old man with recurrent monoarthritis and hyperuricemia were studied. Negatively birefringent crystals in a spherulite form were detected by using a compensated polarized light microscope. It is postulated that in some cases of gout the first stage of crystallization is in the spherulite form.
D000328:Adult; D001168:Arthritis / Q000473:pathology*; D001706:Biopsy; D001718:Birefringence; D003460:Crystallization; D006073:Gout / Q000473:pathology*; D006801:Humans; D008297:Male; D008856:Microscopy, Fluorescence; D013583:Synovial Membrane / Q000473:pathology*