Lymphangiosarcoma in chronic lymphedema that followed dissection of the groin in surgical management of a malignant melanoma.
A 41-year-old white man who had a malignant melanoma in the left lumbar area was treated by wide excision and dissection of the ipsilateral inguinal lymph nodes. Progression and irreversible lymphedema of the left lower extremity developed. Fourteen years after the surgery, numerous purplish plaques and nodules developed on the left leg and thigh. Histologic examination by conventional and electron microscopy yielded the diagnosis of angiosarcoma. The patient died 18 months after the diagnosis was made.
D002908:Chronic Disease; D006119:Groin; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects*; D008204:Lymphangiosarcoma / Q000209:etiology* / Q000473:pathology / Q000648:ultrastructure; D008209:Lymphedema / Q000150:complications*; D008297:Male; D008545:Melanoma / Q000601:surgery*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000601:surgery*