[Experience with psychotropic agents Pyrethia and Contomin in the terminal care of lung cancer patients].
Among patients with lung cancer, those having PS 4 ( Performance Status 4) and cancer pain received " Pyrecon ", a psychotropic agent, consisting of promethazine hydrochloride ( Pyrethia ) and chlorpromazine hydrochloride ( Contomin ). A mixture of 125 mg of Pyrethia and 50 mg of Contomin was diluted in 500 ml of regular IV solution and given through the central vein at a rate of 20 ml/hr. Pyrecon was found to be effective in patients with severe cancer pain in whom Brompton cocktail was ineffective. Pyrecon was also effective in patients whose daily life rhythm was unsteady due to insomnia caused by anxiety or unrest. We suggest that Pyrecon is effective in the treatment of cancer pain.
D000328:Adult; D000368:Aged; D001007:Anxiety; D002746:Chlorpromazine / Q000008:administration & dosage*; D002940:Circadian Rhythm; D004359:Drug Therapy, Combination; D005239:Fear; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D010148:Intractable Pain / Q000188:drug therapy*; D011398:Promethazine / Q000008:administration & dosage*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy; D013727:Terminal Care
D011398:Promethazine; D002746:Chlorpromazine