[Age characteristics of lipoprotein lipase activity and cholesterol levels in various lipoprotein fractions].
In practically healthy from 20 up to 95 years old persons, independently of sex, only slight alterations in the mean content of total cholesterol were noted. However, redistribution of cholesterol occurred between various classes of lipoproteins. There was a decrease of cholesterol content in high density lipoproteins (LPHD) and an increase in cholesterol content in lipoproteins of very low and low density. A positive correlation was found between the activity of postheparin lipoprotein lipase and the content of LPHD cholesterol, thus suggesting the essential role of the hydrolysis rate of triglycerides in the lipoproteins for regulation of LPHD cholesterol content, which are atherogenic factors in atherosclerosis development.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D008071:Lipoprotein Lipase / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D002784:Cholesterol; D008071:Lipoprotein Lipase
Vozrastnye osobennosti aktivnosti lipoproteidlipazy i soderzhaniia kholesterina v razlichnykh fraktsiiakh lipoproteidov.