Crystalline monoclonal antibody Fabs complexed to hen egg white lysozyme.
The Fab of a monoclonal anti-lysozyme antibody (HyHEL-10) has been crystallized as the free Fab and as the Fab-antigen complex. Crystals have also been grown of the antigen complex of the Fab of another monoclonal anti-lysozyme antibody (HyHEL-9), which recognizes a different binding surface of lysozyme. All three crystals diffract to at least 3 A resolution and are suitable for X-ray diffraction studies.
D000818:Animals; D000911:Antibodies, Monoclonal; D003460:Crystallization; D004591:Electrophoresis, Polyacrylamide Gel; D007140:Immunoglobulin Fab Fragments; D009113:Muramidase / Q000276:immunology*; D011200:Poultry; D014961:X-Ray Diffraction
D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D009113:Muramidase