title: [Contribution of pneumococcal serotyping and antibiotyping to the prevention and treatment of pneumococcal infections (1980-1982). Pneumococcal typing and vaccination (1980-1982)].
abstract: During a 3-year period (1980-1982), 594 pneumococcal strains taken from 565 patients were serotyped. The distribution of the serotypes and their prevalence varied by sample and year. The theoretic vaccinal coverage, evaluated for the four main pathologies: pneumonia, otitis, meningitis, bacteriemia, is 79,1%. Among vaccinal serotypes, the types 19, 7, 3, 6, 1, and 23 are the most frequent, representing a cumulative incidence of 57,7%. In our region (Grenoble), the pneumococcus remains very sensitive to antibiotics. No strain resistant to penicillin G was observed. Erythromycin, doxycyclin, chloramphenicol, and cotrimoxazole preserve their potency with, respectively, 2,1%, 1,8%, 1,1%, and 1,9% resistant strains.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000517:prevention & control*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects / Q000276:immunology
chemical_list: D000900:Anti-Bacterial Agents; D001428:Bacterial Vaccines
vernacular_title: Apport de la sérotypie et de l'antibiotypie des pneumocoques à la prévention et au traitement des pneumococcies (1980-1982). Typage des pneumocoques et vaccination (1980-1982).