Regression of pulmonary metastases from cloacogenic carcinoma after cis-platinum/5-fluorouracil treatment.
An 68-year-old man with cloacogenic carcinoma of the anorectal area developed massive pulmonary metastases 4 years after diagnosis; 5-fluorouracil alone failed to cause regression of the lesion, but marked reduction in size of the lesions followed treatment with 2 monthly infusions of fluorouracil followed by low-dose cis-platinum. The remission has been maintained by monthly courses of cis-platinum at a dose of 50 mg/m2, 30 minutes for 11 months.
D000293:Adolescent; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001005:Anus Neoplasms; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D002945:Cisplatin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D011859:Radiography
D002945:Cisplatin; D005472:Fluorouracil