[Balanced hereditary polymorphism and the mortality from cardiovascular diseases in the populations of 17 countries of Europe. I. A correlation analysis].
The correlation analysis of ratios between six polymorphic genetic systems (ABO, MNSs, Rh, Hp, Gm, HLA) and mortality from ishemic heart disease, brain vascular lesions, and hypertensive disease in 17 European populations has been made. A statistically significant correlation has been established between the populational frequency of most of the 50 phenotypes and genes under study, and mortality. The qualitative structure of correlations and their quantitative expression depend on the cause of death, age and sex. The possible mechanisms of relationship between the genetic populational differences and mortality from cardiovascular diseases are discussed.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001789:Blood Group Antigens / Q000235:genetics; D002318:Cardiovascular Diseases / Q000235:genetics* / Q000401:mortality; D005060:Europe; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D012737:Sex Factors
D001789:Blood Group Antigens; D006680:HLA Antigens
Balansirovannyĭ nasledstvennyĭ polimorfizm i smertnost' ot serdechno-sosudistykh zabolevaniĭ v populiatsiiakh semnadtsati stran Evropy. Soobshchenie I. Korreliatsionnyĭ analiz.