Haptoglobin and copper in adjuvant arthritis during the ibuprofen therapy.
Anti-inflammatory effect of ibuprofen was studied on the model of adjuvant arthritis. Its effectiveness was evaluated on the basis of morphological and biochemical indices. The values of haptoglobin and copper in the blood serum were shown to well correlate to clinical exacerbation of adjuvant disease. Haptoglobin appeared to be the index of particular value.
D000818:Animals; D001168:Arthritis / Q000188:drug therapy*; D001169:Arthritis, Experimental / Q000097:blood / Q000188:drug therapy*; D003300:Copper / Q000097:blood*; D005260:Female; D006242:Haptoglobins / Q000378:metabolism*; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D006242:Haptoglobins; D003300:Copper; D007052:Ibuprofen