title: Serum sickness complicating intravenous streptokinase therapy in acute myocardial infarction.
abstract: A case of delayed serum sickness with transient renal impairment is described in a patient who received early high dose intravenous streptokinase following acute myocardial infarction. Review of the literature suggests that serum sickness after streptokinase may occur independently of the dose or route of administration, and could potentially complicate intracoronary streptokinase therapy.
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology*; D005343:Fibrinolytic Agents / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D012713:Serum Sickness / Q000139:chemically induced*; D013300:Streptokinase / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase