An experimental model of a submucosally tunnelled valve for the replacement of the ileo-cecal valve.
An enteric valve to prevent colonic content reflux and to prolong small bowel transit time was created by passing small bowel through a submucosal tunnel in the colon. Barium enema, Gl tract series, and iso- and antiperistaltic pressure measurements showed the valve to be of competence equal to the ileo-cecal valve. Late pathological examination revealed a patent valve with minimal scar formation. The optimal submucosal tunnel length was between 4 and 6 cm. This valve can, theoretically, increase the absorptive capacity in short bowel syndrome and may serve as a substitute for the critically important ileo-cecal valve.
D000818:Animals; D001466:Barium Sulfate; D004285:Dogs; D004733:Enema; D005260:Female; D005769:Gastrointestinal Motility; D007080:Ileocecal Valve / Q000502:physiology / Q000601:surgery*; D007082:Ileum / Q000601:surgery; D007413:Intestinal Mucosa / Q000601:surgery*; D008297:Male; D012778:Short Bowel Syndrome / Q000517:prevention & control
D001466:Barium Sulfate