title: [The significance of "capsular infiltration" of testicular Leydig cells--an autopsy study].
abstract: By means of histiopathologic analysis of testes from 462 autopsy cases of extratesticular diseases, the frequency and degree of so-called "capsular infiltration" of testicular Leydig cells as well as its relationship to hyperplasia of intraparenchymal Leydig cells and atrophy of the seminiferous tubules were semiquantitatively investigated. As a result, a positive correlation was demonstrated between the number of intracapsular Leydig cells and age, and the possibility of this phenomenon as an ageing process was suggested. Simultaneous hyperplastic processes of intraparenchymal Leydig cells were also associated with significantly higher frequency of "capsular infiltration". In addition, the morphogenesis of capsular Leydig-cells as well as several possible mechanisms concerning local control of Leydig cells were discussed from the analogy of other endocrine systems and review of literatures.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D001344:Autopsy; D002648:Child; D006801:Humans; D006965:Hyperplasia; D007985:Leydig Cells / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D013737:Testis / Q000473:pathology*
vernacular_title: Zur Bedeutung der "Kapselinfiltration" der testikulären Leydigzellen--eine Obduktionsstudie.