title: Experimental models for the study of hepatoprotection.
abstract: In the therapy of chronic liver diseases several drugs are currently used. This review summarizes the results of the authors in the therapy of chronic liver diseases with cyanidanol-3, as well as the beneficial effects of the new dihydroquinoline-type antioxidants in acute carbon tetrachloride induced and galactosamine induced liver lesions. In addition, the immunostimulant effects of Aicaphosphate is demonstrated in chronic active hepatitis.
mesh_terms: D000818:Animals; D002392:Catechin / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D002908:Chronic Disease; D004798:Enzymes / Q000097:blood; D006098:Granulocytes / Q000187:drug effects / Q000201:enzymology; D006521:Hepatitis, Chronic / Q000188:drug therapy; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008107:Liver Diseases / Q000188:drug therapy* / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008315:Malondialdehyde / Q000378:metabolism; D051379:Mice; D011804:Quinolines / Q000627:therapeutic use
chemical_list: D004798:Enzymes; D011804:Quinolines; C011923:6,6'-methylene bis(2,2,4-trimethyl-1,2-dihydroquinoline); D008315:Malondialdehyde; D002392:Catechin; C044964:6,6'-methylenebis(2,2-dimethyl-4-methanesulfonic acid-1,2-dihydroquinoline)