title: [Intramuscular premedication with diazepam in a fat emulsion].
abstract: 10 mg of diazepam in fat emulsion was given for premedication intramuscularly to 106 patients. In 53% of the cases patients were well sedated, 33% were apprehensive, 14% anxious. Pain related to the injection was complained of by 4 patients. Plasma concentration of diazepam at induction (60 minutes after the injection) was 130 ng/ml. Compared to diazepam in propylene glycol, pain at the injection side was less frequent while the level of sedation and the plasma concentration of diazepam were similar.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003975:Diazepam / Q000008:administration & dosage* / Q000097:blood; D004655:Emulsions; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D014677:Pharmaceutical Vehicles; D011229:Preanesthetic Medication
chemical_list: D004655:Emulsions; D014677:Pharmaceutical Vehicles; D003975:Diazepam
vernacular_title: Prémédication intra-musculaire par le diazépam en émulsion lipidique.