Identification of 24-hydroxycholesterol in bovine adrenals in both free and esterified forms and in bovine brains as its sulfate ester.
24-Hydroxycholesterol was found to be present in bovine adrenals in a concentration of 2-3 micrograms/kg and in larger amounts (10-12 micrograms/kg) as a saponifiable ester. No solvolyzable sulfate ester was detected. In bovine brains, however, the sulfate ester of this sterol was found in a concentration of 84 micrograms/kg. A procedure for the synthesis of [7-3H] 24S-hydroxycholesterol is described.
D000311:Adrenal Glands / Q000032:analysis*; D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D006888:Hydroxycholesterols / Q000302:isolation & purification*; D013464:Sulfuric Acids
D006888:Hydroxycholesterols; D013464:Sulfuric Acids; C044563:24-hydroxycholesterol