title: Hemispheric lateralization in 47,XXY Klinefelter's syndrome boys.
abstract: Thirty-two boys with a 47,XXY karyotype were compared with chromosomally normal male controls in their performance on six tasks of hemispheric specialization. The results revealed that the 47,XXY subjects had smaller asymmetries on left hemisphere tasks and larger asymmetries on right hemisphere tasks than controls. Analyses of individual right and left side scores revealed that the atypical lateral asymmetries of the 47,XXYs were due to a shift toward greater right hemisphere involvement on four of the six measures. It was postulated that the slower fetal growth rates of the extra X chromosome group might contribute to their atypical hemispheric specialization and the failure of their left hemisphere to gain dominance over their right in language processing.
mesh_terms: D001307:Auditory Perception / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D002648:Child; D004007:Dichotic Listening Tests; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007713:Klinefelter Syndrome / Q000503:physiopathology / Q000523:psychology*; D007802:Language; D008297:Male; D014796:Visual Perception / Q000502:physiology