Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines.
We have investigated the potential for using cyclosporin A to increase the efficiency with which Epstein-Barr virus-transformed human lymphoblast lines can be prepared. Use of this immunosuppressive drug has permitted the development of a procedure with success rates exceeding 95% despite the processing of very large numbers of samples.
D002460:Cell Line; D002472:Cell Transformation, Viral / Q000187:drug effects; D003524:Cyclosporins / Q000494:pharmacology*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000382:microbiology
D003524:Cyclosporins