title: A convenient synthesis of adenylyl-(2'----5')-adenylyl-(2'----5')-adenosine (2-5A core).
abstract: A simple synthesis of adenylyl-(2'----5')-adenylyl (2'----5')-adenosine (2-5A core) has been achieved on the basis of selective 3'-O-silylation of 5'-O-p-monomethoxytrityladenosine and chemo-selective formation of the 2'-5' internucleotide linkage using N-unprotected nucleosides.
mesh_terms: D000227:Adenine Nucleotides / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007202:Indicators and Reagents; D007536:Isomerism
chemical_list: D000227:Adenine Nucleotides; D007202:Indicators and Reagents; C031128:adenylyl-(2'-5')-adenylyl-(2'-5')adenosine