Comparison of clinico-epidemiological features of lung cancer patients with and without a history of smoking.
In order to study the characteristics of lung cancer in smokers and nonsmokers, clinico-epidemiological features of 943 lung cancer patients treated in the Aichi Cancer Center Hospital from 1964-77 were analyzed according to their smoking histories. About 70% of both male and female patients who smoked fell in Group I (squamous cell, small cell and large cell carcinomas), while of those who did not smoke, 50% of the male and 36% of the female patients fell in Group I. The mean age of the patients who smoked was about 60 yr and that of the nonsmokers was 55 yr in both men and women. It was estimated that about 70% of the Group I tumors originated from main, segmental or subsegmental bronchi, but half of the Group II tumors (adenocarcinoma) originated from peripheral bronchi in both smokers and nonsmokers. One-third of the tumors were seen in the apical and subapical segments of the upper lobes regardless of the smoking history. There was no difference between the survival rates for the patients with and without a history of smoking.
D000367:Age Factors; D005260:Female; D006801:Humans; D007564:Japan; D008175:Lung Neoplasms / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012907:Smoking