[Mechanism of cancer induction by radiation].
The mechanism of radiation carcinogenesis was reviewed on the basis of recent knowledge on cancer-related mutation, oncogene-activation, and monoclonal origin of cancer. Evidence for the systemic suppression of cancerized cells in situ was presented from experimental data concerning whole-body vs. partial-body irradiation, and single vs. repeated irradiation.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000209:etiology; D004260:DNA Repair; D005260:Female; D005354:Fibrosarcoma / Q000209:etiology; D008297:Male; D051379:Mice; D009381:Neoplasms, Radiation-Induced; D009857:Oncogenes / Q000528:radiation effects; D011829:Radiation Dosage; D051381:Rats; D011919:Rats, Inbred Strains; D012513:Sarcoma, Experimental / Q000209:etiology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology