title: Cholinergic neurons in the nucleus tegmenti pedunculopontinus pars compacta and the caudoputamen of the rat: a light and electron microscopic immunohistochemical study using a monoclonal antibody to choline acetyltransferase.
abstract: Large neurons in the nucleus tegmenti pedunculopontinus pars compacta (TPC) of the rat were shown to have choline acetyltransferase (ChAT) immunoreactivity by light and electron microscopic immunohistochemistry using a monoclonal antibody to ChAT. The ChAT-positive TPC neurons had triangular or multipolar cell bodies with diameters of 20-50 micron. The ultrastructural features of the ChAT-positive TPC neurons were similar to those of ChAT-positive neurons in the caudoputamen; each neuron had a distinct, pale nucleus with an indented nuclear envelope and large, cytoplasm-containing, well-developed endoplasmic reticulum and pale mitochondria.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D002421:Caudate Nucleus / Q000166:cytology*; D002795:Choline O-Acetyltransferase / Q000276:immunology; D006651:Histocytochemistry; D007120:Immunochemistry; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000166:cytology / Q000648:ultrastructure; D010275:Parasympathetic Nervous System / Q000166:cytology*; D011149:Pons / Q000166:cytology*; D011699:Putamen / Q000166:cytology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000911:Antibodies, Monoclonal; D002795:Choline O-Acetyltransferase