Restoring patency of thrombosed catheters with cryopreserved urokinase.
In order to eliminate wasting vials of urokinase, 5000 U/ml aliquots were reconstituted and frozen. The urokinase remained effective for clearing thrombosed catheters for as long as 9 months. When catheters become occluded, patency can be restored by previously frozen urokinase.
D002404:Catheterization / Q000009:adverse effects*; D005615:Freezing; D006801:Humans; D013927:Thrombosis / Q000517:prevention & control*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
D014568:Urokinase-Type Plasminogen Activator