title: Response of gastric acid and gut hormones in biliary tract reconstruction using an interposed jejunum or ileum in dogs.
abstract: Ten dogs were used to investigate the changes in gut hormones; gastrin, secretin, GIP, and gut-GLI, as well as gastric acid secretion after a test-meal loading following a cholecystoduodenostomy interposing a portion of the jejunum or the ileum. Although the changes in the response of plasma gut hormones to the test-meal were observed, the amount of acid output after the biliary tract reconstruction did not differ from that before the operations in either the jejunal interposition cholecystoduodenostomy or the ileal interposition cholecystoduodenostomy. Therefore, from the standpoint of gastric acid secretion, they are both recommendable procedures for biliary tract reconstruction. It was difficult, however, to interpret the change of gut hormone release in relation to gastric acid secretion. It is presumed that the release of gut hormones after the reconstructive procedure is mainly affected by the part of the small intestine which is used for the reconstruction.
mesh_terms: D000818:Animals; D004285:Dogs; D005704:Gallbladder / Q000601:surgery*; D005744:Gastric Acid / Q000378:metabolism*; D005749:Gastric Inhibitory Polypeptide / Q000378:metabolism; D005755:Gastrins / Q000378:metabolism; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D004763:Glucagon-Like Peptides / Q000378:metabolism; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D012633:Secretin / Q000378:metabolism; D013997:Time Factors
chemical_list: D005755:Gastrins; D005768:Gastrointestinal Hormones; D012633:Secretin; D005749:Gastric Inhibitory Polypeptide; D004763:Glucagon-Like Peptides