Plant anticancer agents. XXX: Cucurbitacins from Ipomopsis aggregata (Polemoniaceae).
Isocucurbitacin B (I), 3-epi-isocucurbitacin B (II), and cucurbitacin B (III) were identified as the principal cytotoxic constituents of Ipomopsis aggregata (Pursh) V. Grant (Polemoniaceae). The structure of the new compound, II, was determined through analysis of its spectrometric characteristics.
D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D002277:Carcinoma; D002460:Cell Line; D054728:Cucurbitacins; D006801:Humans; D009303:Nasopharyngeal Neoplasms; D009374:Neoplasms, Experimental / Q000188:drug therapy; D010944:Plants / Q000032:analysis; D014315:Triterpenes / Q000302:isolation & purification*
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes; C041246:cucurbitacin B; C041247:isocucurbitacin B; D054728:Cucurbitacins