title: Postoperative wound infections following cardiac surgery: significance of contaminated cases performed in the preceding 48 hours.
abstract: Postoperative wound infections following open heart cardiac surgery increased markedly after hospital relocation (7 of 77 v 4 of 320; p = .0007). Of the multiple identified risk factors, significant patient and procedural association included prolonged operative time of infected patients (384 minutes +/- 115 SD v 318 +/- 67, p = .025) and operation in a room used within the previous 48 hours for a contaminated case (4/7 infected v 10/67 not infected; p = .023). Several defects were discovered in the air handling system. After appropriate changes, the infection rate decreased in the next 12 months (1 of 109; p less than .02). Other concurrent surgical wound infection rates remained unchanged suggesting that defective air handling may have impacted only on the open heart cardiac surgery patients. Preceding contaminated surgery and prolonged operative time were associated with postoperative wound infections in cardiac surgery.
mesh_terms: D000328:Adult; D000368:Aged; D000389:Air Conditioning; D006348:Cardiac Surgical Procedures; D003428:Cross Infection / Q000453:epidemiology; D004196:Disease Outbreaks / Q000453:epidemiology*; D005845:Georgia; D006745:Hospital Bed Capacity, 300 to 499; D006787:Hospitals, Veterans; D006801:Humans; D007430:Intraoperative Care; D008875:Middle Aged; D009873:Operating Rooms; D012306:Risk; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology; D013997:Time Factors; D014691:Ventilation