title: Microcomputer programs for graphic analysis of nucleic acid and protein sequences.
abstract: Four computer programs are described which allow two amino acid or DNA sequences to be compared for homology, the results being displayed in a 2-dimensional array on a printer page. The programs also may be used to visualize repeated sequences or dyad symmetry within a DNA sequence. Two of the four programs may be used with any printer, the other two require a printer with graphics capability. Many options are available including using only a portion of a sequence, specifying a window to demonstrate more significant structures and special restrictions on matching such as excluding the third base in a codon. Written in the C programming language, the programs run under the CP/M 80 operating system, and may be copied in binary format through a modem. They are also available for the IBM/PC.
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003201:Computers; D004247:DNA / Q000235:genetics*; D003626:Data Display; D008722:Methods; D008838:Microcomputers; D011506:Proteins / Q000235:genetics*; D012984:Software; D013329:Structure-Activity Relationship
chemical_list: D011506:Proteins; D004247:DNA