Prostaglandin E1 responsive ductus at 11 months of age.
An 11-month-old boy with congestive heart failure and an intermittently closing patent ductus arteriosus (PDA) is presented. During cardiac catheterization, the ductus proved responsive to prostaglandin E1. Permanent closure of the PDA could not be attained with indomethacin. The infant underwent surgical ligation of the PDA.
D000527:Alprostadil; D004359:Drug Therapy, Combination; D004374:Ductus Arteriosus, Patent / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D007223:Infant; D008026:Ligation; D008297:Male; D011458:Prostaglandins E / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D011458:Prostaglandins E; D014665:Vasodilator Agents; D000527:Alprostadil; D007213:Indomethacin