Evaluation of the neurotoxicity of dapsone in the mouse model.
Effect of DDS was studied using the mouse model. It was observed that DDS did not have any neurotoxic effect. On the contrary it showed a protective action towards the nerve, when administered in the early stages following definite establishment of nerve lesions.
D000818:Animals; D003622:Dapsone / Q000633:toxicity*; D005260:Female; D007918:Leprosy / Q000473:pathology*; D051379:Mice; D008815:Mice, Inbred Strains; D012584:Sciatic Nerve / Q000187:drug effects* / Q000648:ultrastructure
D003622:Dapsone