Action of the antibiotics of the iturin group on artificial membranes.
The action of iturin A and bacillomycin L on vesicles of dipalmitoylphosphatidylcholine (DPPC) and DPPC-cholesterol was studied. Iturin A destroyed the vesicles, bacillomycin L bound with DPPC vesicles and destroyed vesicles containing DPPC and cholesterol. These results are discussed in comparison with the action of antibiotics of the iturin group on cytoplasmic membranes.
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D002250:Carbon Radioisotopes; D055598:Chemical Phenomena; D002621:Chemistry; D002784:Cholesterol; D007700:Kinetics; D008081:Liposomes; D010455:Peptides; D010456:Peptides, Cyclic; D011663:Pulmonary Surfactants; D014316:Tritium
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D002250:Carbon Radioisotopes; D008081:Liposomes; D010455:Peptides; D010456:Peptides, Cyclic; D011663:Pulmonary Surfactants; D014316:Tritium; C013579:iturin A; C015015:bacillomycin L; D002784:Cholesterol