Polymorph function, complement and immunoglobulins in Nigerian patients with pneumococcal infections.
Polymorphonuclear function was found adequate in vitro in Nigerian patients with pneumococcal infections by a bactericidal assay against type I pneumococcus in the same opsonin system. In the classical complement screening 40 per cent of the patients had values below 50 per cent of standard, perhaps reflecting deficiencies of the early classical pathway components.
D000293:Adolescent; D000328:Adult; D001770:Blood Bactericidal Activity; D002648:Child; D003176:Complement C3 / Q000032:analysis*; D011415:Complement Factor B / Q000032:analysis; D003170:Complement Pathway, Alternative; D003171:Complement Pathway, Classical; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D009549:Nigeria; D011008:Pneumococcal Infections / Q000276:immunology*
D003176:Complement C3; D007136:Immunoglobulins; D011415:Complement Factor B