[N-acetyltransferase activity during growth of the transplantable Pliss lymphosarcoma and during pregnancy in rats].
Study of the distribution of female noninbred rats according to N-acetyltransferase activity has permitted the conclusion to be derived that the animals may have a "slow", "intermediate" and "fast" phenotype of acetylation. It was discovered that the rate of N-acetyltransferase activity increased 1.5-2-fold on days 12 and 15 after transplantation of Pliss's lymphosarcoma. The time course of changes in N-acetyltransferase activity was characterized by individual features. The pattern of changes in N-acetyltransferase activity in pregnancy was dependent on the initial acetylation phenotype: in animals with a "slow" and "intermediate" phenotype of acetylation, the activity ascended by the 21st day of pregnancy, whereas in animals with a "fast" phenotype of acetylation, it declined.
D000123:Acetyltransferases / Q000378:metabolism*; D000818:Animals; D005260:Female; D008228:Lymphoma, Non-Hodgkin / Q000201:enzymology* / Q000473:pathology; D008297:Male; D009368:Neoplasm Transplantation; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000201:enzymology* / Q000473:pathology; D051381:Rats
D000123:Acetyltransferases
Izuchenie aktivnosti N-atsetiltransferazy v dinamike rosta transplantiruemoĭ limfosarkoma Plissa i pri beremennosti u krys.