Improved discrimination of normal and malignant tissue using 1H NMR relaxation time measurements at 2.18 MHz.
The 1H NMR spin-lattice relaxation time (T1), spin-spin relaxation time (T2), and spin-lattice relaxation time in the rotating frame (T1rho) were determined for Novikoff hepatoma, Walker-256 Carcinosarcoma, Sarcoma-180 and Ehrlich Ascites tumor as well as for 7 normal tissues in the rat at 2.18 MHz. T1 values yielded improved discrimination of normal and malignant tissue compared to previous results at higher frequencies.
D000818:Animals; D002279:Carcinoma 256, Walker / Q000175:diagnosis; D002286:Carcinoma, Ehrlich Tumor / Q000175:diagnosis; D008114:Liver Neoplasms, Experimental / Q000175:diagnosis; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009369:Neoplasms / Q000175:diagnosis*; D051381:Rats; D011919:Rats, Inbred Strains; D012510:Sarcoma 180 / Q000175:diagnosis