Anti-ulcer and antisecretory activity of selected imidazopiperidines.
New thioureas and ureas with an interesting anti-ulcer and antisecretory activity are disclosed. The chemical synthesis, determination of the structure, and structure-activity relationships of the compounds are discussed.
D000818:Animals; D000897:Anti-Ulcer Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D005750:Gastric Juice / Q000378:metabolism*; D008297:Male; D010276:Parasympatholytics; D010880:Piperidines / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control; D013329:Structure-Activity Relationship
D000897:Anti-Ulcer Agents; D010276:Parasympatholytics; D010880:Piperidines