Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus.
Activity of eleven antimicrobial agents against methicillin-, methicillin- and rifampin-resistant Staphylococcus aureus was studied using a microtiter broth dilution technique. Coumermycin was the most active agent. Vancomycin, rifampin, fusidic acid and N-formimidoyl-thienamycin showed excellent activity against methicillin-resistant St. aureus (MRSA). Antimicrobial susceptibility pattern was similar for MRSA and methicillin- and rifampin-resistant St. aureus. 8% of MRSA were resistant to trimethoprim and sulfamethoxazole.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D008712:Methicillin / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D012293:Rifampin / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D008712:Methicillin; D012293:Rifampin