Eosinophilic cystitis with giant cells. A light microscopic and ultrastructural study.
We report a case of eosinophilic cystitis. The wall of the urinary bladder was infiltrated by abundant eosinophils, numerous mast cells, neutrophils, and dispersed giant cells. Electron microscopic examination showed that the giant cells were macrophage polykaryocytes. We discuss their possible relationship to an allergic reaction, as well as to the previous use of radiation therapy 23 years ago. Granulomas were not observed.
D002467:Cell Nucleus / Q000648:ultrastructure; D003556:Cystitis / Q000473:pathology*; D003593:Cytoplasm / Q000648:ultrastructure; D004802:Eosinophilia / Q000473:pathology*; D004804:Eosinophils / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D010586:Phagocytes / Q000648:ultrastructure; D001743:Urinary Bladder / Q000473:pathology* / Q000648:ultrastructure