[Significance of vascular changes in the colposcopic diagnosis of precancerous and early stages of cervical cancer].
Blood vessels are visible in an average of 80% of patients on whom colposcopy is performed. This percentage share increases if there are pathological changes. The following vascular types occur as characteristic criteria in cervical intraepithelial neoplasia (CIN) and in carcinoma, their classification being based on structural properties such as calibre, long and intercapillary spaces, shape and arrangement of the vessels, as well as their functional state: Abnormal vessels; pathological vessels of the 1st and 2nd degree; uncharacteristic vessels (also known as "troubled vessels"). The author discusses the architecture, adaptive vasodilation and formation of new vessels in connection with morphological changes in the epithelium. Their occurrence is evaluated statistically, and an inference is drawn from these studies on the efficiency of vascular diagnosis. The following conclusions are arrived at on the basis of the examined material: The abnormal vessel result from a proliferation of the abnormal or dysplastic epithelium. The pathological vessels of the 1st degree occur as maximum type of adaptive vascular change resulting in the course of carcinomatous proliferation. The pathological changes of the 2nd degree, on the other hand, become visible as new formations in invasively growing carcinomas only. There is a connection between the presence of pathological types of vessels and the carcinomatous degeneration of the epithelium and the invasive growth. Assessment of the vessels must be performed parallel to the assessment of the epithelium via acetic acid or lactic acid test. This facilitates colposcopic diagnosis of precarcinomic and early stages of cervical carcinoma and enables conclusions to be drawn on an invasive growth of the carcinoma.
D001808:Blood Vessels / Q000473:pathology; D002584:Cervix Uteri / Q000098:blood supply; D003127:Colposcopy; D005260:Female; D006801:Humans; D011230:Precancerous Conditions / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*
Die Bedeutung der Gefässveränderungen bei der kolposkopischen Diagnostik der Vor- und Frühstadien des Zervixkarzinoms.