[Glandular kallikrein in chronic recurrent parotitis].
Salivary kallikrein was measured in the parotid saliva of 11 patients suffering from chronic recurrent parotitis and 15 healthy control persons. While in the control group kallikrein levels from 1-4 U/l could be registrated, the results obtained from patients were significantly elevated and varied between 23,45 U/l and 89,41 U/l. Release of kallikrein from destroyed duct cells is suggested to be the origin of the elevated salivary levels of this enzyme in chronic recurrent parotitis. A leakage of glandular kallikrein into the interstitial fluid and thereby release of kallidin from kininogen is discussed as a possible mechanism in the development of this disease.
D000328:Adult; D002908:Chronic Disease; D006801:Humans; D007610:Kallikreins / Q000378:metabolism*; D010306:Parotid Gland / Q000201:enzymology*; D010309:Parotitis / Q000201:enzymology*; D012463:Saliva / Q000201:enzymology; D012472:Salivation
D007610:Kallikreins
Glanduläres Kallikrein bei chronisch-rezidivierender Parotitis.