Arginine vasotocin and aggression in rats.
Pinealectomized (PX) and sham animals were administered either AVT (1 ng/kg) or vehicle (1 ml H20). Boxing-kicking-biting episodes were significantly reduced by administration of AVT, F(1,21) = 8.09, p less than 0.009. Crawling under behavior was increased in PXH20 animals (p less than 0.05). Non-aggressive rearing was decreased by administration of AVT, F(1,21) = 4.75, p less than 0.04. These results are in agreement with previous findings that AVT lowers emotionality-arousal. Results are discussed in terms of vasotonergic effects on central monoamines.
D000374:Aggression / Q000187:drug effects*; D000818:Animals; D006801:Humans; D008297:Male; D008550:Melatonin / Q000494:pharmacology; D010870:Pineal Gland / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D014668:Vasotocin / Q000494:pharmacology*
D008550:Melatonin; D014668:Vasotocin