Protective effect of specific elastase inhibitor in experimental pulmonary emphysema.
The inhibitory effect of synthetic elastase inhibitor was studied in experimental emphysema. The development of emphysema was totally prevented by this substance. According to the authors' opinion the administration of synthetic elastase inhibitors can be considered as a new possibility in the treatment of pulmonary emphysema.
D000336:Aerosols; D000590:Amino Acid Chloromethyl Ketones / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D011656:Pulmonary Emphysema / Q000517:prevention & control*; D051381:Rats
D000336:Aerosols; D000590:Amino Acid Chloromethyl Ketones; C026704:methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone; D010196:Pancreatic Elastase