[Inhibition of the effect of immunocytotherapy in leukemia in mice under stress and the possibilities of its withdrawal].
The immunosuppressant effect of immobilization stress on the systems that are responsible for C57BL/6 mice protection from EL-4 leukemic cells has been demonstrated in experimental adoptive immunocytotherapy. The data are provided on the efficacy of the use of interferon and its inducer (polyI.polyC) in mouse donors of splenocytes at the poststressor period with a purpose of recovering the ability to exert a cytotherapeutic effect during adoptive transfer to tumor-bearing mice.
D000818:Animals; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular; D007116:Immunization, Passive; D007165:Immunosuppression Therapy; D007167:Immunotherapy; D007942:Leukemia, Experimental / Q000276:immunology* / Q000628:therapy; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D013154:Spleen / Q000276:immunology / Q000637:transplantation; D013315:Stress, Psychological / Q000276:immunology*
D003520:Cyclophosphamide
Ingibitsiia éffekta immunotsitoterapii leĭkozov mysheĭ pri stresse i vozmozhnosti ee otmeny.