[Comparative evaluation of the myocardial resistance of animals with hereditary hypertension and normal arterial pressure to the damaging action of stress].
In normotensive WKY and August rats the 6-hour immobilized stress has been shown to result in decrease of heart muscle extensibility, in depression of developed tension and reduction of myocardial resistance to hypoxic and calcium contractures. This complex does not develope the post-stress disturbances of miocardial function in spontaneously hepertensive rats (SHR) which heart muscle is characterized by reduced adrenoreactivity. The heart adrenoreactivity is supposed to be one of the important factors determining its resistance to stress damage in animals of different strains.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002118:Calcium / Q000494:pharmacology; D006321:Heart / Q000503:physiopathology*; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology; D066298:In Vitro Techniques; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000503:physiopathology*
D002118:Calcium
Sravnitel'naia otsenka rezistentnosti serdechnoĭ myshtsy zhivotnykh s nasledstvennoĭ gipertonieĭ i normal'nym arterial'nym davleniem k povrezhdaiushchemu deĭstviiu stressa.