[Effect of ethinyl estradiol sulfonate on the urethral epithelium after bilateral oophorectomy].
The influence of ethinylestradiolsulfonate on the cytological image of the urethra was examined on 11 women who underwent the salpingo-oophorectomia bilateralis. The criterion of the proliferative effect was the Dynamic-Estrogenicity-Index (DEI). After a 6 to 8 weeks treatment at a dosage of one milligram weekly a DEI of 7,27 (+/- 0,74) was attainable. From this point of view we can also summarize a very good urethrotrophic effectiveness. Ethinylestradiolsulfonate is recommended for the treatment of affection on the urethra, especially of those in which an estrogen deficit is the genuine reason or a favoured factor by women after hysterectomia and salpingo-oophorectomia bilateralis for substitution with hormones.
D000328:Adult; D002369:Castration; D004341:Drug Evaluation; D004847:Epithelial Cells; D004848:Epithelium / Q000187:drug effects; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013997:Time Factors; D014521:Urethra / Q000166:cytology / Q000187:drug effects*
C025723:ethinyl estradiol sulfonate; D004997:Ethinyl Estradiol
Der Einfluss von Athinylöstradiolsulfonat auf das Epithel der Urethra nach bilateraler Oophorektomie.