Psychopharmacological profile of diphenylhydantoin in mice.
The pharmacological profile of diphenylhydantoin has some common features with that of classical antidepressants: it decreases motor activity in mice it shortens the period of immobility of mice in the "behavioral despair" test it antagonizes palpebral ptosis induced by reserpine in mice.
D000818:Animals; D001058:Apomorphine / Q000008:administration & dosage; D001462:Barbital / Q000008:administration & dosage; D001522:Behavior, Animal / Q000187:drug effects*; D001763:Blepharoptosis / Q000139:chemically induced; D004347:Drug Interactions; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010095:Oxotremorine / Q000008:administration & dosage; D010672:Phenytoin / Q000494:pharmacology*; D012110:Reserpine / Q000037:antagonists & inhibitors; D015016:Yohimbine / Q000008:administration & dosage
D015016:Yohimbine; D010095:Oxotremorine; D001462:Barbital; D010672:Phenytoin; D012110:Reserpine; D001058:Apomorphine