title: Frequency of large granular lymphocytes in peripheral blood of healthy persons and breast cancer patients.
abstract: The frequency of large granular lymphocytes (LGL) in the peripheral blood of healthy persons (n = 56) and breast cancer patients (31 cases with stage-I and -II disease and 42 cases with stage-III and -IV disease) was studied. The frequency of LGL in peripheral blood was significantly depressed in cancer patients, and particularly in patients with advanced breast cancer.
mesh_terms: D001943:Breast Neoplasms / Q000097:blood* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology*