title: [Thyroid pathology of newborn infants of mothers with Basedow's disease].
abstract: Of 15 neonates born to mothers presenting with Graves' disease, who were admitted for presumptive thyroid disorder, 6 presented with neonatal thyrotoxicosis, 4 with goiter and/or hypothyroidism, and 5 presented with euthyroidism. In cases with thyrotoxicosis, the mothers were not or insufficiently treated. Evolution was regressive in 5 instances, there was a craniostenosis and persisting hyperthyroidism in one case. In cases with goiter and/or hypothyroidism, on the other hand, the mothers were correctly treated, and neonatal manifestations were benign and transient. This emphasizes both the importance of supervising gravidic hyperthyroidism and the complexity of materno-foetal relationship in thyroid diseases.
mesh_terms: D000367:Age Factors; D005260:Female; D006042:Goiter / Q000235:genetics; D006111:Graves Disease / Q000235:genetics*; D006801:Humans; D006980:Hyperthyroidism / Q000235:genetics; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013960:Thyroid Function Tests
vernacular_title: Pathologie thyroïdienne des nouveau-nés de mères basedowiennes.