title: [Medico-genetic consultation and clinico-social prognosis of epileptics].
abstract: The results of the clinical-genetic examinations of 291 families of the general population are discussed. The authors present tables of empirical risk of recurrent epilepsy and lesser epileptic manifestations (epileptoid psychopathy, childhood convulsions) among the relatives of probands with regard to the degree of kinship, the familial (above all parenthood) identical and non-identical aggravated heridity, clinical polymorphism of the disease and populational characteristics. The questions of the clinical and social prognosis of epilepsy in specific clinical-genetic familial situations are also outlined. The deontologic aspects of the medical-genetic counselling of patients with a familial history of epilepsy are discussed. Groups with high and very high risk of recurrent epilepsy are identified. The findings presented make it possible to improve the medical-genetic counselling as well as clinical and social prognosis in specific familial-genetic situations in epilepsy.
mesh_terms: D000293:Adolescent; D003241:Consanguinity; D004200:Diseases in Twins; D004827:Epilepsy / Q000517:prevention & control*; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D011247:Pregnancy; D012306:Risk; D012640:Seizures / Q000517:prevention & control; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic
vernacular_title: Mediko-geneticheskoe konsul'tirovanie i kliniko-sotsial'noe prognozirovanie bol'nykh épilepsieĭ.