title: [Chorangiomas (hemangiomas of the placenta). II. Pathologic-anatomic comparison of neonatal complications].
abstract: Fetal and neonatal complications in chorangiomas of different size, in multiple chorangiomas and in cases accompanied with hydramnios were reviewed in 110 cases from literature inclusively 7 own observations. In accordance with other examiners we found an increasing perinatal mortality, especially of the antenatal mortality rate corresponding with an increasing tumor size. Chorangiomas with hydramnios had a mortality of 80 per cent. In these cases only a small part was caused by fetal immaturity or severe malformations. Comparing mean placental weight and mean neonatal weight small for date babies had a relative and absolute augmentation of placental tissue in relation to a control group. The conclusion from these findings and the fact that in own cases heavy disorders of villous differentiation could be observed is, that the fetal fate may be fundamentally influenced not only by the hemodynamic disturbance caused by the tumor, but also by the degree of placental differentiation. Large hemangiomas are ought to detect during pregnancy by ultrasound. In singular cases it may be to prevent fetal hypoxia by termination of pregnancy.
mesh_terms: D000740:Anemia / Q000209:etiology; D000013:Congenital Abnormalities / Q000209:etiology; D004487:Edema / Q000209:etiology; D005260:Female; D005313:Fetal Death / Q000209:etiology; D006391:Hemangioma / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology*; D010922:Placenta Diseases / Q000150:complications*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic
vernacular_title: Uber Chorangiome (Hämangiome der Plazenta). II. Kindliche Komplikationen im pathologisch-anatomischen Vergleich.