[Acute hemorrhagic necrosis of the breast following treatment with Cumarin].
A case of hemorrhagic necrosis of the breast is reported in a thirty-four year old woman who received Cumarin treatment for deep leg vein thrombosis and pulmonary embolism. It was necessary to remove the breast. The microscopic examination showed complete blockage of the vessels by fibrin thrombi in almost all veins. The cause of this venous thrombosis was explained as a Shwartzman-Sanarelli-Phenomenon.
D015110:4-Hydroxycoumarins / Q000009:adverse effects*; D000328:Adult; D001941:Breast Diseases / Q000139:chemically induced* / Q000601:surgery; D005260:Female; D006801:Humans; D009336:Necrosis; D010644:Phenprocoumon / Q000009:adverse effects*; D012790:Shwartzman Phenomenon / Q000209:etiology
D015110:4-Hydroxycoumarins; D010644:Phenprocoumon
Akute hämorrhagische Nekrose der Mamma nach Cumarintherapie.