[Course of urinary schistosomiasis over 3 consecutive years after treatment with metrifonate in a dry savanna village in Upper Volta].
In a dry savanna village in Upper-Volta, after mass treatment with metrifonate (four doses of 7,5 mg/kg at three weeks intervals) checking of the population was carried out for the three following years. In children and adolescents, results show a progressive decline in the cure rate (69.0% one year after treatment, 38.1% three years after treatment) and in egg-output reduction (69.9% one year after treatment, 75.4% three years after treatment). In adults, these two parameters still remain high three years after treatment (90.0% for cure rate and 87.3% for egg-output reduction). The authors point out that in a dry savanna village with a sedentary population and a transmission limited to a small collection of water, chemotherapy even employed alone is an appreciable control method to relieve populations.
D000293:Adolescent; D000328:Adult; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D010270:Parasite Egg Count; D012552:Schistosomiasis / Q000188:drug therapy*; D013997:Time Factors; D014236:Trichlorfon / Q000627:therapeutic use*; D014556:Urine / Q000469:parasitology; D014570:Urologic Diseases / Q000188:drug therapy*
D014236:Trichlorfon
Evolution sur trois années consécutives de la schistosomose urinaire après traitement au metrifonate dans un village de savane seche de Haute-Volta.