title: The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA.
abstract: The complete nucleotide sequence of rabbit muscle aldolase mRNA has been determined from recombinant cDNA clones and from a primer-extended cDNA synthesis on the mRNA template. The sequence is composed of 1375 nucleotides, exclusive of the poly(A) tails. The 5'-untranslated region contains 62 bases including a potential ribosome-binding site. The 3'-untranslated region is 221 bases long. The remaining 1092 nucleotides are in an open reading frame coding for 364 amino acids. There is a single methionine residue preceding the NH2-terminal proline. The deduced amino acid sequence corrects a number of discrepancies between published structures as well as assignments previously missed. The sequences of the cloned cDNAs suggests there may be microheterogeneity in the messenger RNA population.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000032:analysis; D005634:Fructose-Bisphosphate Aldolase / Q000235:genetics*; D007527:Isoenzymes / Q000235:genetics*; D009132:Muscles / Q000201:enzymology*; D012333:RNA, Messenger / Q000032:analysis*; D011817:Rabbits
chemical_list: D007527:Isoenzymes; D012333:RNA, Messenger; D004247:DNA; D005634:Fructose-Bisphosphate Aldolase