Heterophile antibodies to rabbit erythrocytes in human sera and identification of the antigen as a glycolipid.
Normal human sera contain heterophile hemagglutinins to rabbit erythrocytes which are different from anti-B isoantibody and other heterophile antibodies such as Hanganutziu-Deicher antibody or Paul-Bunnell antibody. The antigen to this antibody was purified from rabbit erythrocyte stroma, and identified as pentaglycosyl ceramide, Gal(alpha 1-3)Gal(beta 1-4)GlcNAc(beta 1-3)Gal(beta 1-4)Glc-Cer.
D000818:Animals; D000910:Antibodies, Heterophile / Q000302:isolation & purification*; D002554:Cerebrosides / Q000097:blood* / Q000276:immunology; D055598:Chemical Phenomena; D002621:Chemistry; D004912:Erythrocytes / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D011817:Rabbits
D000910:Antibodies, Heterophile; D002554:Cerebrosides; C041200:pentaglycosyl ceramide