[Tocolysis with hexoprenalin and salbutamol in a clinical comparison].
140 patients with a threatening premature birth at the greater than or equal to 24-less than 37 week of gestation were in this study randomly treated with hexoprenalin or salbutamol. In 77% in the hexoprenalin and in 74% in the salbutamol group the weight of the newborn was greater than or equal to 2500 g. In 66% in both study groups the birth occurred after the completed 37 weeks of gestation. During infusion of hexoprenalin tachycardia in mothers occurred statistically highly significantly less than during salbutamol. 11% of the mothers in the hexoprenalin group had side-effects during infusion compared to 30% in the salbutamol group. The correlation between the tocolysis-index (Baumgarten) and the prolongation-index (Richter) given by the regression lines facilitates in some measure the comparison of different tocolytic drugs concerning its tocolytic effect.
D000420:Albuterol / Q000009:adverse effects / Q000627:therapeutic use*; D001724:Birth Weight; D005260:Female; D006594:Hexoprenaline / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D010627:Phenethylamines / Q000627:therapeutic use*; D011247:Pregnancy; D011446:Prospective Studies; D013610:Tachycardia / Q000139:chemically induced
D010627:Phenethylamines; D006594:Hexoprenaline; D000420:Albuterol
Tokolyse mit Hexoprenalin und Salbutamol im klinischen Vergleich.