title: [Antiamnestic properties of pyrazole dicarboxylic acid derivatives in rats].
abstract: Eight derivatives of pyrazole dicarboxylic acid (IEM-565, IEM-476, IEM-1332, IEM-474, IEM-373, IEM-440, IEM-1333, IEM-439) have been studied in rats for the ability to abolish the amnesia of passive avoidance behavior induced by electroconvulsive shock IEM-476, IEM-373 and IEM-439 have proved to be the most efficacious.
mesh_terms: D000647:Amnesia / Q000188:drug therapy* / Q000209:etiology; D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004597:Electroshock; D004924:Escape Reaction / Q000187:drug effects; D005042:Etimizol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007093:Imidazoles; D008297:Male; D011720:Pyrazoles / Q000627:therapeutic use*; D051381:Rats
chemical_list: D007093:Imidazoles; D011720:Pyrazoles; D005042:Etimizol
vernacular_title: Izuchenie antiamnesticheskikh svoĭstv proizvodnykh pirazoldikarbonovoĭ kisloty u krys.