Polycyclic aromatic hydrocarbon profiles of pyrolysed tobacco products commonly used in India.
The polycyclic aromatic hydrocarbon (PAH) profile of bidi (an indigenous substitute for cigarettes in India), masheri (a charred tobacco product used for cleaning teeth) and Indian snuff was determined. The effect of the extracts of these tobacco products on the liver microsomal mixed function oxygenase system was studied. Cytochrome P-450 and benzo[a]pyrene (B[a]P) hydroxylase levels were significantly increased.
D000818:Animals; D001579:Benzopyrene Hydroxylase / Q000096:biosynthesis; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004790:Enzyme Induction / Q000187:drug effects; D007194:India; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010947:Plants, Toxic; D011083:Polycyclic Compounds / Q000032:analysis*; D012906:Smoke / Q000032:analysis*; D014026:Nicotiana / Q000032:analysis*; D014030:Tobacco, Smokeless / Q000032:analysis
D011083:Polycyclic Compounds; D012906:Smoke; D003577:Cytochrome P-450 Enzyme System; D001579:Benzopyrene Hydroxylase