title: [Bone histomorphometry: observations in cases of renal osteodystrophy].
abstract: The AA report a histomorphometric study performed by measuring square areas and volumes of bone tissue. Furthermore, in 7 patients with osteodystrophy secondary to chronic renal failure, the AA investigated the amount of osteoid tissue and the presence of osteoblasts and osteoclasts. They noted signs of secondary hyperparathyroidism with increase of osteoclastic activity and fibrous metaplasia of the bone marrow associated with osteomalacia. The same patients were examined after treatment with, Vit D3 active preparations separately administered: and the AA especially noted decrease of the osteoclastic reabsorption and of the volume of osteoid tissue after the treatment with 1,25 (OH)2 D3 more than with 25 OH D3.
mesh_terms: D000328:Adult; D001862:Bone Resorption; D001842:Bone and Bones / Q000473:pathology*; D002112:Calcifediol / Q000627:therapeutic use; D002117:Calcitriol / Q000627:therapeutic use; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008875:Middle Aged
chemical_list: D002117:Calcitriol; D002112:Calcifediol
vernacular_title: Contributo allo studio dell'istomorfometria ossea: osservazioni in casi di osteodistrofia renale.