[Trial of onager oil in the treatment of schizophrenia in connection with the prostaglandin deficiency hypothesis].
Ten schizophrenic patients were treated with onager oil. It was hypothesized that E1 prostaglandin deficiency underlies the different biological disorders of schizophrenia. The clinical and biological results were disappointing. However the fact that the patients had been severely ill for a long time might have to be taken into account. Moreover, the blood level of gamma-linolenic acid was normal, at the start, in all the patients.
D000328:Adult; D000527:Alprostadil; D000818:Animals; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009539:Nicotinic Acids; D009821:Oils / Q000032:analysis / Q000627:therapeutic use*; D010527:Perissodactyla; D011458:Prostaglandins E / Q000172:deficiency*; D012559:Schizophrenia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*
D005227:Fatty Acids; D009539:Nicotinic Acids; D009821:Oils; D011458:Prostaglandins E; D000527:Alprostadil
Essai de l'huile d'onagre dans le traitement de la schizophrénie en rapport avec l'hypothèse d'un déficit en prostaglandine.