title: An internal standard for porphyrin analysis.
abstract: The routine clinical analysis of the porphyrin precursors of heme requires an internal standard to determine the efficiency of the analytical procedure used. 2-Vinyl-4-hydroxymethyldeuteroporphyrin IX has been prepared as an internal standard. Its application to porphyrin analysis has been demonstrated using high-performance liquid chromatographic resolution of the uro- to protoporphyrins in normal and porphyric urine.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003905:Deuteroporphyrins / Q000032:analysis / Q000138:chemical synthesis*; D005243:Feces / Q000032:analysis; D006801:Humans; D008099:Liver / Q000032:analysis; D011166:Porphyrins / Q000032:analysis* / Q000138:chemical synthesis* / Q000592:standards / Q000652:urine; D011524:Protoporphyrins / Q000032:analysis; D012015:Reference Standards; D014578:Uroporphyrins / Q000032:analysis
chemical_list: D003905:Deuteroporphyrins; D011166:Porphyrins; D011524:Protoporphyrins; D014578:Uroporphyrins; C042954:2-vinyl-4-(hydroxymethyl)deuteroporphyrin IX