Can postictal suppression of the perforant path - fascia dentata responses account for the ECS-induced anterograde amnesia in rats?
Electroconvulsive shock (ECS) decreases fascia dentata responses to entorhinal stimulation by 50% in unanesthetized rats. Synaptic potentials and population spikes return to pre-ECS level during 1 h and 3 h, respectively. This recovery rate is compared with the dynamics of ECS-induced anterograde amnesia.
D000200:Action Potentials; D000647:Amnesia / Q000503:physiopathology*; D000818:Animals; D004597:Electroshock; D006624:Hippocampus / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology; D051381:Rats; D013997:Time Factors