title: [Second tumor following Hodgkin's disease].
abstract: This article deals with the case of a three year old boys suffering from a M. Hodgkin stage IA who was given telecobalt radiation in 1975. A year later he was again given radiation because of a local recurrence and additionally treated by chemotherapy according to the MOPP scheme. Six and a half years after the first diagnosis we noticed the incidence of a not differentiated neurogenic intracerebral tumor. The question if chemotherapy and radiotherapy possibly cause the incidence of second malignancies is now under discussion.
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols; D001932:Brain Neoplasms / Q000209:etiology*; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage / Q000009:adverse effects; D009364:Neoplasm Recurrence, Local / Q000209:etiology*; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D011344:Procarbazine / Q000008:administration & dosage / Q000009:adverse effects; D011867:Radioisotope Teletherapy; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents; D003037:Cobalt Radioisotopes; D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D011241:Prednisone
vernacular_title: Zweittumor nach Morbus Hodgkin.