title: DNCB contact sensitization in leprosy: its comparison with other CMI tests.
abstract: 76 Lepromatous, 50 non-lepromatous cases of leprosy and 20 apparently healthy individuals were tested for Dinitrochlorobenzene contact sensitization. Only one lepromatous case and one apparently healthy individual showed negative result. E-rosette counts and leucocyte migration inhibition test were performed in 22 lepromatous, 10 non-lepromatous cases and 10 apparently healthy individuals who were all DNCB positive. Of these 2 lepromatous, 8 non-lepromatous cases and all the 10 apparently healthy individuals showed lepromin positivity. Average E-rosette counts (percentage) and mean leucocyte migratory index were significantly lower in lepromatous as compared to non-lepromatous cases.
mesh_terms: D002464:Cell Migration Inhibition; D004137:Dinitrochlorobenzene; D006801:Humans; D007111:Immunity, Cellular; D007114:Immunization; D007916:Lepromin / Q000276:immunology; D007918:Leprosy / Q000145:classification / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology; D012397:Rosette Formation
chemical_list: D004137:Dinitrochlorobenzene; D007916:Lepromin