title: [Premature fetal membrane rupture: report of a case of severe intrauterine fungal infection].
abstract: A case of extremely rare intra-uterine candida infection is reported following premature rupture of the membranes. The diagnostic possibilities by transabdominal amniocentesis and determination of the causative organism in the amniotic fluid are presented. Even systemic antimykotic treatment is not capable of treating intra-uterine candidiasis sufficiently. This is proved among other parameters by the concentration of miconazol in the amniotic fluid and in the plasma of the newborn.
mesh_terms: D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000032:analysis / Q000382:microbiology; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002179:Candidiasis, Cutaneous / Q000209:etiology*; D005260:Female; D005315:Fetal Diseases / Q000188:drug therapy; D005322:Premature Rupture of Fetal Membranes / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology* / Q000382:microbiology; D008825:Miconazole / Q000627:therapeutic use; D011247:Pregnancy; D014591:Uterine Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology
chemical_list: D008825:Miconazole
vernacular_title: Der vorzeitige Blasensprung: Falldarstellung einer schweren intrauterinen Pilzinfektion.