Studies on a new antibiotic FR-900336 taxonomy, isolation and characterization.
A new lipophilic antibiotic, FR-900336 was isolated from a culture of Streptomyces sioyaensis subsp. tanegashimaensis . FR-900336 is light yellow and has a molecular formula C30H30NO13C1 . The characterization by IR, UV, 1H NMR and 13C NMR spectra makes a quinone structure very probable. FR-900336 is active against Gram-positive bacteria and fungi.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D004353:Drug Evaluation, Preclinical; D005285:Fermentation; D005658:Fungi / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011809:Quinones / Q000302:isolation & purification / Q000633:toxicity; D013302:Streptomyces / Q000145:classification / Q000254:growth & development*
D000900:Anti-Bacterial Agents; D011809:Quinones; C041437:FR 900336