title: The source of biliary infections associated with T-tube drainage.
abstract: The purpose of this study was to determine the source of organisms responsible for biliary infection associated with T-tube placement. Two groups of patients who had had T-tubes placed following common bile duct exploration were studied. In one group of 34 patients, bacterial cultures were taken daily from the drainage bag and the lumen of the T-tube. In the second group of patients, paired daily bacterial cultures were taken from the T-tube lumen and the skin tract surrounding the T-tube. Results of the first group showed the drainage bag to be the initial site of infection in seven cases, with "descending" infection from the patient's skin occurring in 27 cases, 14 in whom the organism was initially present in the bile while in the other 13 the organism appeared later. In the second group, of 32 isolates only five were found extraluminally before they appeared within the lumen, these five being all Staphylococcus epidermidis. Thus the majority of bile infections occurring after T-tube placement were found to originate from the patient's own biliary tree or skin.
mesh_terms: D000368:Aged; D001646:Bile / Q000382:microbiology; D001659:Biliary Tract / Q000382:microbiology*; D001660:Biliary Tract Diseases / Q000209:etiology*; D004322:Drainage / Q000009:adverse effects* / Q000295:instrumentation; D006801:Humans; D007239:Infections / Q000209:etiology*; D008875:Middle Aged; D012867:Skin / Q000382:microbiology