title: Atracurium besylate in paediatric anaesthesia.
abstract: Atracurium was evaluated in clinical anaesthesia in 50 children undergoing elective surgery. The time to onset of maximum block (182 seconds) was similar to that of vecuronium but shorter than that of pancuronium as previously reported. The duration of clinical relaxation (33 minutes) is between those of vecuronium and pancuronium. The antagonism of block at 25% recovery was easy. There was no untoward cardiovascular effects but skin reactions were observed in over 30% of patients.
mesh_terms: D000005:Abdomen / Q000601:surgery; D000293:Adolescent; D000768:Anesthesia, General; D001279:Atracurium; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal; D007546:Isoquinolines / Q000494:pharmacology; D008297:Male; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology; D013508:Ophthalmologic Surgical Procedures; D013997:Time Factors
chemical_list: D007546:Isoquinolines; D009466:Neuromuscular Blocking Agents; D001279:Atracurium