Chemical modification of triamcinolone acetonide to improve liposomal encapsulation.
The 21-palmitate of triamcinolone acetonide was synthesized to aid in the liposomal encapsulation of the drug. Encapsulation efficiency of triamcinolone acetonide-21-palmitate was 85%, compared with 5% for the parent drug.
D002626:Chemistry, Pharmaceutical; D008081:Liposomes; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000032:analysis* / Q000138:chemical synthesis
D008081:Liposomes; C041990:triamcinolone acetonide 21-palmitate; D014222:Triamcinolone Acetonide