title: The effects of erythrocyte contamination on pokeweed mitogen induced immunoglobulin synthesis in man.
abstract: Red blood cell (RBC) contamination of cultures of peripheral blood mononuclear cells does not suppress pokeweed mitogen (PWM) induced immunoglobulin synthesis. At supra-optimal doses of PWM immunoglobulin production is enhanced in the presence of RBCs. The degree of RBC contamination is a factor to be considered in interpreting the results obtained with PWM induced Ig synthesis in disease.
mesh_terms: D000921:Antibody-Producing Cells / Q000276:immunology / Q000378:metabolism; D004912:Erythrocytes; D006801:Humans; D007136:Immunoglobulins / Q000096:biosynthesis*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism*; D011043:Pokeweed Mitogens / Q000494:pharmacology*
chemical_list: D007136:Immunoglobulins; D011043:Pokeweed Mitogens