Two new trichothecenes, PD 113,325 and PD 113,326.
Two new trichothecenes, PD 113,325 and PD 113,326, were isolated and their structures were shown to be 12'-hydroxy-2'-(E)-verrucarin J (1a) and a stereoisomer of satratoxin H (3).
D000818:Animals; D000970:Antineoplastic Agents; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D012717:Sesquiterpenes / Q000302:isolation & purification*; D013237:Stereoisomerism; D014255:Trichothecenes / Q000032:analysis / Q000302:isolation & purification* / Q000627:therapeutic use
D000970:Antineoplastic Agents; D012717:Sesquiterpenes; D014255:Trichothecenes; C014184:satratoxin H; C035445:verrucarin J; C042904:PD 113325