Chronobiologic and metabolic characterization of rats fed low or high linoleic acid diets.
The influence of a modified endogenous prostanoid synthesis on circadian rhythmicity at different functional levels (prostanoid formation, behavioural parameters, circulatory indices, hematological parameters, energy metabolism) was investigated. The daily rhythmic changes observed for all parameters were partly modified by the variation of dietary linoleate intake.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002940:Circadian Rhythm / Q000187:drug effects; D004041:Dietary Fats / Q000494:pharmacology*; D004327:Drinking Behavior / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D006454:Hemoglobins / Q000378:metabolism; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000172:deficiency / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D011458:Prostaglandins E / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D013929:Thromboxane B2 / Q000096:biosynthesis*; D013931:Thromboxanes / Q000096:biosynthesis*
D004041:Dietary Fats; D006454:Hemoglobins; D008041:Linoleic Acids; D008112:Liver Glycogen; D011458:Prostaglandins E; D013931:Thromboxanes; D013929:Thromboxane B2; D019787:Linoleic Acid