title: [Pedigree in which multiple pregnancy is combined with sterility].
abstract: A case of simultaneous hereditary transmission of twinning and sterility in a jewish family from Novosibirsk is described. The both characters are transmitted by male and female. It is suggested that twinning and sterility are connected with the action of one dominant mutation with multiple pleiotropic action on propagation system. The action of two alleles in homozygotes is additive. The importance of special search for and study of similar situations for understanding mechanisms of twinning and sterility occurrence in man is discussed.
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics; D000328:Adult; D005260:Female; D005313:Fetal Death / Q000235:genetics; D005799:Genes, Dominant; D006801:Humans; D007247:Infertility, Female / Q000235:genetics*; D007585:Jews; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012800:Siberia; D014427:Twins
vernacular_title: Rodoslovnaia, v kotoroĭ mnogoplodie sochetaetsia s besplodiem.