Replacement of partially resected canine urethra by polytetrafluoroethylene.
Twelve Gore-Tex grafts were used to replace a section of the urethra in 10 dogs. The grafts functioned well for three months, but at six months there was calcification and fistula formation. A fibrous tube developed around the grafts rather than a regenerated urethra. There was no epithelial regrowth on the internal surface.
D000818:Animals; D004285:Dogs; D004848:Epithelium / Q000502:physiology; D008297:Male; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications / Q000209:etiology; D019736:Prostheses and Implants; D012038:Regeneration; D014521:Urethra / Q000502:physiology / Q000601:surgery*; D014525:Urethral Stricture / Q000601:surgery; D014548:Urinary Fistula / Q000209:etiology
D011138:Polytetrafluoroethylene