Transfer of immunity against Hymenolepis nana in mice with lymphoid cells or serum from infected donors.
Immunity to Hymenolepis nana was adoptively transferred to recipient mice of 4 strains using mesenteric lymph node cells (MLNC), spleen cells (SC), and/or serum taken from infected donor mice. Donor cells capable of transferring immunity appeared in the mesenteric lymph nodes and spleen at an early stage (5 days) after infection. Immunity was most effectively transferred with MLNC and immune serum did not enhance this effect. It is suggested that effective immunity to H. nana involves both antibody and T cell-mediated inflammatory events.
D000818:Animals; D005260:Female; D006925:Hymenolepiasis / Q000276:immunology* / Q000469:parasitology; D007106:Immune Sera / Q000008:administration & dosage / Q000276:immunology*; D007116:Immunization, Passive / Q000379:methods; D008198:Lymph Nodes / Q000276:immunology*; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000276:immunology*; D008643:Mesentery; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000276:immunology*
D007106:Immune Sera