Site-dependence of invasiveness of ECA109 human oesophageal carcinoma cells in nude mice.
ECA109 human oesophageal carcinoma cells were injected either subcutaneously or intraperitoneally into BALB/CATc 1-nu/nu mice. After 23 weeks tumours were examined histologically and by scanning electron microscopy. Subcutaneous ECA109 tumours were well-delineated without signs of invasion. By contrast, intra-abdominal tumours invaded into the abdominal wall and abdominal organs. This result provides us with another example of site-dependence of invasion in vivo.
D000818:Animals; D002460:Cell Line; D004938:Esophageal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D008855:Microscopy, Electron, Scanning; D009361:Neoplasm Invasiveness; D009368:Neoplasm Transplantation; D013997:Time Factors