Impact of neonatal catecholamine treatment on adult response to vasopressin and norepinephrine.
The present experiments have shown that neonatal imprinting with certain catecholamines had a significant impact on adult vascular adrenergic response, and on adult response to vasopressin as well. This finding not only substantiates the existence of a hormonal imprinting mechanism, but also suggests a certain (receptor-level) interaction between the vasopressin and catecholamine receptors involved in vascular contraction.
D000818:Animals; D000831:Animals, Newborn; D001013:Aorta, Thoracic / Q000187:drug effects / Q000502:physiology; D004837:Epinephrine / Q000494:pharmacology*; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology*; D009638:Norepinephrine / Q000494:pharmacology*; D051381:Rats; D014667:Vasopressins / Q000494:pharmacology*
D014667:Vasopressins; D009638:Norepinephrine; D004837:Epinephrine