title: [Growth and biotin synthesis of Sporobolomyces pararoseus and Rhizopus delemar under different substrate ratios].
abstract: Biotin synthesis by the yeast Sporobolomyces pararoseus and the microscopic fungus Rhizopus delemar was studied in batch cultures at different substrate ratios in the medium. The overall (exocellular + endocellular) biotin content in the yeast was 4.5-6.0 micrograms per 1 g of biomass on different media and did not depend on the growth phase. The content of biotin in the fungus was 7.5-9.0 micrograms per 1 g of biomass and depended neither on the growth phase nor on the quantitative ratio between components of the growth medium. In contrast to the yeast, the content of exocellular biotin per 1 g of the mycelium increased with the fungal growth, and the yield of biotin was maximal (25-29 micrograms/g) at the stationary growth phase. The maximal rate of biotin synthesis by the both organisms coincided in time with their maximal growth rate.
mesh_terms: D001710:Biotin / Q000096:biosynthesis*; D003470:Culture Media / Q000378:metabolism; D003904:Mitosporic Fungi / Q000254:growth & development* / Q000378:metabolism; D012233:Rhizopus / Q000254:growth & development* / Q000378:metabolism; D013997:Time Factors
chemical_list: D003470:Culture Media; D001710:Biotin
vernacular_title: Rost i sintez biotina Sporobolomyces pararoseus i Rhizopus delemar pri razlichnykh limitatsiiakh.