title: Localization of the haptoglobin alpha and beta genes (HPA and HPB) to human chromosome 16q22 by in situ hybridization.
abstract: Human haptoglobin (Hp) is a protein that binds free hemoglobin and circulates in plasma of vertebrates as a tetrachain (alpha beta)2 structure. This study maps HPA and HPB, the genes encoding the Hp alpha and beta chains to human chromosome band 16q22 by in situ hybridization.
mesh_terms: D002874:Chromosome Mapping; D002902:Chromosomes, Human, 16-18; D004247:DNA / Q000378:metabolism; D005796:Genes; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D046911:Macromolecular Substances; D008677:Metaphase; D009693:Nucleic Acid Hybridization; D010957:Plasmids
chemical_list: D006242:Haptoglobins; D046911:Macromolecular Substances; D004247:DNA