title: DF-2: a fastidious fermentative gram-negative rod.
abstract: Current information is reviewed from 26 cases of human infection by DF-2, a fastidious gram-negative rod. These infections are typically associated with dog contact or dog bites. Underlying diseases or prior splenectomy are predisposing factors for severe infection with a potentially fatal outcome. The methods for isolating and identifying the microorganism are given. Long, thin, slowly growing, oxidase-positive, catalase-positive gram-negative rods that do not grow on MacConkey agar should suggest DF-2. Although testing of antimicrobial susceptibility is problematic, DF-2 has been found to be resistant to aminoglycosides. The drug of choice is penicillin.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D001733:Bites and Stings / Q000382:microbiology*; D004285:Dogs; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010403:Penicillin Resistance; D010406:Penicillins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins