[Disorders of the kallikrein-kinin, renin-angiotensin and sympathetic-adrenal systems in chronic kidney failure patients during hemodialysis treatment].
Blood plasma renin activity, blood adrenaline and noradrenaline concentrations, and the kallikrein-kinin system were studied in 48 patients with chronic renal failure (CRF). Thirty-five patients with normal blood pressure and controlled hypertension (group I) showed a decrease in blood plasma renin and kallikrein-kinin system deficiency. In 13 patients with uncontrollable hypertension (group II), the renin-angiotensin and sympathoadrenal systems were found to be activated in the presence of the kallikrein-kinin system deficiency. Disorders of normal interrelations between the renin-angiotensin, sympathoadrenal and kallikrein-kinin systems in patients with CRF are determined to a significant degree by upset regulation of the metabolism of biologically active substances by the lungs in connection with the occurrence of microemboli in the pulmonary circulation during hemodialysis.
D000311:Adrenal Glands / Q000503:physiopathology*; D000328:Adult; D004837:Epinephrine / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D007610:Kallikreins / Q000097:blood*; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy; D007705:Kinins / Q000097:blood*; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D006435:Renal Dialysis; D012084:Renin-Angiotensin System; D013564:Sympathetic Nervous System / Q000503:physiopathology*
D007705:Kinins; D007610:Kallikreins; D009638:Norepinephrine; D004837:Epinephrine
Narisheniia kallikrein-kininovoĭ, renin-angiotenzinoĭ i simpatiko-adrenalovoĭ sistem u bol'nykh s khronicheskoĭ pochechnoĭ nedostatochnosti v protsesse lecheniia gemodializom.