Plasma concentrations of testosterone and 5 alpha-dihydrotestosterone around luteolysis in goats and their behavioural effects after ovariectomy.
In non-pregnant goats, increased peripheral plasma concentrations of testosterone and 5 alpha-dihydrotestosterone (DHT) occurred at the start of luteal regression and before the day of oestrus. Intramuscular injections of testosterone (10 mg) in arachis oil to progesterone-primed ovariectomized goats induced oestrous behaviour; similar injections of DHT failed to do so. It is suggested that conversion of testosterone to oestrogens by aromatization induces oestrous behaviour in the goat while reduction of testosterone to DHT does not.
D000818:Animals; D002369:Castration; D003338:Corpus Luteum / Q000502:physiology*; D013196:Dihydrotestosterone / Q000097:blood*; D004971:Estrus / Q000187:drug effects*; D005260:Female; D006041:Goats; D011247:Pregnancy; D011374:Progesterone / Q000494:pharmacology*; D011863:Radioimmunoassay; D013739:Testosterone / Q000097:blood* / Q000494:pharmacology
D013196:Dihydrotestosterone; D013739:Testosterone; D011374:Progesterone