title: Non-Hodgkin lymphoma following Hodgkin's disease. A case report.
abstract: A 40-year-old male developed 66 months after diagnosis of Hodgkin's disease a non-Hodgkin lymphoma of high grade malignancy. Initially he had been treated by irradiation because of Hodgkin's disease PS IIA. After 2 years of remission he had relapsed and had received MOPP and CCNU. After 2 years without any therapy he developed the secondary neoplasm. With increasing frequency of long term survivors late complications, either therapy related or caused by immunologic defects, are observed.
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols; D002945:Cisplatin / Q000627:therapeutic use; D006689:Hodgkin Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007813:Laparotomy; D008130:Lomustine / Q000627:therapeutic use; D008223:Lymphoma / Q000209:etiology* / Q000628:therapy; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage; D008727:Methotrexate / Q000627:therapeutic use; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D008130:Lomustine; D002945:Cisplatin; D011241:Prednisone; D008727:Methotrexate