Normal physical and mental development of 6-year-old children whose mothers were treated antenatally with prednisolone.
83 prednisolone-treated and 57 control children of a previous study demonstrating benefits of antenatal steroid prophylaxis of IRDS were reexamined at the age of 6 years. The prednisolone children were slightly higher and heavier, but no significant differences between steroid and control groups were noted in any other characteristics including IQ, psychosocial development, EEG, ophthalmology and audiology. THe results confirm the finding that antenatal steroid prophylaxis has no long-term hazards to the fetus.
D002648:Child; D002657:Child Development / Q000187:drug effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007360:Intelligence / Q000187:drug effects; D008297:Male; D008606:Mental Processes / Q000187:drug effects*; D011239:Prednisolone / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control
D011239:Prednisolone