Correlation of estrogen receptor level and lipid staining in breast carcinoma.
Intracytoplasmic lipid was demonstrated in 10% or more of the cells in 13 (26%) of 50 estrogen receptor (ER)-positive breast carcinomas and in four (14.8%) of 27 ER-negative breast carcinomas. Thus, proportionately more positive tumors contained significant amounts of intracytoplasmic lipid. The difference, however, was not statistically significant. Furthermore, the presence of lipid as a test to predict the ER status is not useful because of its low efficiency and predictive value.
D000328:Adult; D000368:Aged; D001391:Azo Compounds; D001943:Breast Neoplasms / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis*; D004396:Coloring Agents; D003593:Cytoplasm / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis*
D001391:Azo Compounds; D004396:Coloring Agents; D008055:Lipids; D011960:Receptors, Estrogen; C011049:oil red O