[Polyneuropathy during treatment with carbimazole].
A patient developed polyneuropathy during carbimazole treatment for thyrotoxicosis. Electrophysiological data and a neuromuscular biopsy suggested a combined axonal and demyelinative lesion together with microvasculitis. Physiopathological hypotheses are discussed.
D001369:Axons / Q000187:drug effects; D002231:Carbimazole / Q000009:adverse effects* / Q000627:therapeutic use; D004576:Electromyography; D006111:Graves Disease / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D010525:Peripheral Nerves / Q000473:pathology; D011129:Polyradiculoneuropathy / Q000139:chemically induced* / Q000473:pathology; D014657:Vasculitis / Q000473:pathology
D002231:Carbimazole
Polyneuropathie au cours d'un traitement par le carbimazole.