Hypercalcemic hypertension in hemodialysis.
Hypertension refractory to standard dialystic maneuvers developed in a 25-year old female who had been on long-term hemodialysis. Lowering the target dry weight and adding antihypertensives did not ameliorate the hypertension. Hypercalcemia, due to vitamin D administration, was discovered and, following its correction, there was subsequent normalization of the blood pressure. This report discusses some of the mechanisms whereby calcium can interface with blood pressure regulatory mechanisms in individuals with end stage renal disease.
D000328:Adult; D002117:Calcitriol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000209:etiology; D006973:Hypertension / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy; D006435:Renal Dialysis / Q000009:adverse effects*
D002117:Calcitriol