Effects of ethyl alcohol and acetaldehyde on certain biochemical parameters of blood in Wistar rats.
Ethyl alcohol injected intraperitoneally to rats in a dose of 3 g/kg of body weight caused hypoglycaemia which was not observed after similar administration of acetaldehyde in a dose od 0.3 g/kg. The serum levels of lipids and total cholesterol were unchanged after administration of ethyl alcohol while acetaldehyde decreased to cholesterol level 0.5, 1.5 and 3 hours after administration. Both these compounds raised the serum activity of AspAT and AlAT, and this rise was observed 0.5 hour after ethyl alcohol and 6 hours after acetaldehyde.
D000079:Acetaldehyde / Q000494:pharmacology*; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001774:Blood Chemical Analysis; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D000431:Ethanol / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008055:Lipids / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D001786:Blood Glucose; D008055:Lipids; D000431:Ethanol; D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000079:Acetaldehyde