title: [Comparative analysis of the therapeutic effect of endolumbar insufflation of air and nitrous oxide in patients with epileptic seizures].
abstract: A total of 272 patients with epileptic seizures were examined and treated, using pneumoencephalography (PEG). In 185 cases, the cerebral fluid was insufflated with air and in 87 cases with nitrous oxide. Nitrous oxide was administered at a faster rate and in larger amounts but the patients tolerated this manipulation much easier. In the nitrous oxide group, the seizures abated in 49 patients (56.32%). In the air group, remission occurred in 45 patients (23.78%). A more prominent therapeutic effect of nitrous oxide was observed in all patients irrespective of either their age or the etiology, character and frequency of epileptic attacks or the EEG and PEG changes. Nitrous oxide is recommended for wide application for diagnostic and therapeutic purposes.
mesh_terms: D004827:Epilepsy / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D007278:Injections, Spinal; D009609:Nitrous Oxide / Q000627:therapeutic use*; D011011:Pneumoencephalography
chemical_list: D009609:Nitrous Oxide
vernacular_title: Sravnitel'nyĭ analiz lechebnogo éffekta éndoliumbal'nogo vvedeniia vozdukha i zakisi azota u bol'nykh s épilepticheskimi pripadkami.