Gamma radiation produced performance decrement in rat as assessed with the accelerod.
Early transient incapacitation (ETI) and/or performance decrement (PD) is a reduction in performance during the first 30 min after exposure to a relatively high, rapidly delivered dose of ionizing radiation. The accelerod provides a sensitive measure of functional impairment in neurotoxic evaluations of chemical agents and demonstrates that the motor performance of gamma-radiation-exposed Sprague-Dawley rats was significantly different from that of sham-radiated controls.
D000818:Animals; D003037:Cobalt Radioisotopes / Q000009:adverse effects*; D008297:Male; D011597:Psychomotor Performance / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D003037:Cobalt Radioisotopes