[Effect of T-activin on thymus involution in mice].
The effect of T-activin on thymus involution in mice was studied. T-activin in a dose of 1.0 micrograms/mouse was injected into young male (CBA X C57BL)F1 mice weighing 24.0 +/- 2.0 g daily for 20 days. Morphometric analysis of the thymus was made 6 months after the treatment with T-activin was completed. It was found that T-activin induced the suppression of physiological involution of the thymus together with the enhancement of the processes of thymocyte transformation and proliferation.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009929:Organ Size / Q000187:drug effects; D010455:Peptides / Q000494:pharmacology*; D013949:Thymus Extracts / Q000494:pharmacology*; D013950:Thymus Gland / Q000033:anatomy & histology / Q000187:drug effects*; D013997:Time Factors
D010455:Peptides; D013949:Thymus Extracts; C036191:T-activin
Vliianie T-aktivina na involiutsiiu timusa u mysheĭ.