title: Signal search analysis: a new method to localize and characterize functionally important DNA sequences.
abstract: The generation of "signal search data" represents a general method of describing the common properties of a set of DNA sequences presumed to be functionally analogous. Besides the detailed description of this method we present two computer programs which use signal search data as input data: One that processes them to a "constraint profile" and another one which lists over-represented "signals" of potential functional relevance. To illustrate the possibilities of our method we have analysed a set of transcription initiation sites of sea urchin histone genes.
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics*; D005796:Genes; D006657:Histones / Q000235:genetics; D007256:Information Systems; D009876:Operon; D012617:Sea Urchins / Q000235:genetics; D012984:Software
chemical_list: D006657:Histones; D004247:DNA