[Surgical treatment of Basedow's disease. I--Traditions and new methods in preparation for thyroidectomy: use of dexamethasone].
The combination of dexamethasone (2 mg every 6 hours) carbimazole (15 mg every 8 hours) and potassium iodide (XV drops every 8 hours) has been proposed in the preparation of 21 patients with hyperthyroid Graves' disease for surgery. The combination was administered for 6 days and the subtotal thyroidectomy was performed on day 7. All patients had normal serum Triiodothyronine levels after 4 days of such treatment. This combined drug therapy appears to be a rapid, sage and effective preparation for thyroid surgery in patients with Graves' disease and should replace conventional preparation with carbimazole and potassium iodide and beta-blocker preparation in all cases where there are no contra-indications to the use of corticosteroids.
D000328:Adult; D002231:Carbimazole / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D011193:Potassium Iodide / Q000627:therapeutic use; D011292:Premedication; D013963:Thyroid Hormones / Q000097:blood; D013965:Thyroidectomy
D013963:Thyroid Hormones; D011193:Potassium Iodide; D003907:Dexamethasone; D002231:Carbimazole
Traitement chirurgical de la maladie de Basedow. I--Traditions et nouveautés dans la préparation à la thyroïdectomie: utilisation de la dexaméthasone.