title: [Combination of oxybutynin chloride (Ditropan) with intermittent catheterization in the treatment of neurogenic bladder in childhood: results on continence].
abstract: Nowadays Intermittent Catheterization (I.C.) is considered the treatment of choice in patients with neurogenic bladder dysfunction, because of its easy handling and good results. Renal function preservation, urinary tract infections prevention and continence can be achieved by this method. In particular, I.C. per sè improves continence quality in many cases, but, in the majority of them the best results can be obtained by drug therapy addition, having in mind a more direct action on to detrusor compliance and/or bladder neck tone. Oxybutynin Chloride (Ditropan)(-) is the first choice drug, even in childhood, in cases of neurogenic bladder dysfunction, for its anticholinergic, antispastic and analgesic properties. From 1978, 48 children with neurogenic bladder have been treated by I.C. Out of them, 27 have had drug therapy (Oxybutynin Chloride-Ditropan) in addition to I.C., according to indications of clinical, radiologic and urodynamics findings. Results on continence are discussed.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D010276:Parasympatholytics / Q000627:therapeutic use*; D011859:Radiography; D001750:Urinary Bladder, Neurogenic / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D014546:Urinary Catheterization / Q000379:methods*; D014549:Urinary Incontinence / Q000188:drug therapy
chemical_list: D008333:Mandelic Acids; D010276:Parasympatholytics; C005419:oxybutynin
vernacular_title: Associazione dell'ossibutinina cloridrato (Ditropan) al cateterismo intermittente nel trattamento della vescica neurologica in età pediatrica: risultati sulla continenza.