Isolation and DNA sequence of full-length cDNA for human preapolipoprotein CIII.
A full-length cDNA clone for apolipoprotein CIII has been isolated from a human fetal liver cDNA library constructed in the vector lambda gt10. The clone spans 677 nucleotides, including a 48-bp 5'-untranslated segment, 300 bp of coding sequence, and a 276-bp 3'-untranslated segment. The deduced amino acid sequence includes a 79-amino acid mature polypeptide and a 20-amino acid amino-terminal signal sequence. The signal sequence was compared with those of other lipoproteins.
D001056:Apolipoproteins C / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D006801:Humans; D008099:Liver / Q000502:physiology; D011498:Protein Precursors / Q000235:genetics*
D001056:Apolipoproteins C; D011498:Protein Precursors; D004247:DNA