Detergent-resistant Streptococcus faecium derivatives that display conditional penicillin lysis.
Three spontaneous derivatives of Streptococcus faecium ATCC 9790, originally isolated as conditionally Triton X-100 detergent-resistant at 25 degrees C, displayed normal penicillin-induced rates of lysis at 37 degrees C but substantially reduced rates of lysis and killing at 25 degrees C. The addition of exogenous unsaturated fatty acids at 25 degrees C restored wild-type penicillin lysis rates.
D003902:Detergents / Q000633:toxicity*; D007700:Kinetics; D017830:Octoxynol; D010403:Penicillin Resistance; D010406:Penicillins / Q000633:toxicity*; D011092:Polyethylene Glycols / Q000633:toxicity*; D013291:Streptococcus / Q000187:drug effects*; D013501:Surface-Active Agents / Q000633:toxicity*; D013816:Thermodynamics
D003902:Detergents; D010406:Penicillins; D013501:Surface-Active Agents; D011092:Polyethylene Glycols; D017830:Octoxynol