[Aseptic necrosis of the femur head as a complication of intensive cytostatic, glucocorticoid and radiation therapy of lymphogranulomatosis].
Aseptic necrosis of femoral head was observed in 12 cases of Hodgkin's disease. The available data suggest that aseptic necrosis was induced by the treatment of Hodgkin's disease. Patients who have received a course of combined therapy (polychemotherapy including glucocorticoids+radiation of hip joints) should be referred to the group at risk for development of this complication.
D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000209:etiology*; D005938:Glucocorticoids / Q000009:adverse effects*; D006689:Hodgkin Disease / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000009:adverse effects; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects; D011344:Procarbazine / Q000009:adverse effects; D011859:Radiography; D011867:Radioisotope Teletherapy / Q000009:adverse effects*; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013997:Time Factors; D014750:Vincristine / Q000009:adverse effects
D005938:Glucocorticoids; D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D011241:Prednisone
Asepticheskiĭ nekroz golovki bedrennoĭ kosti kak oslozhnenie intensivnoĭ tsitostaticheskoĭ, gliukokortikoidnoĭ i luchevoĭ terapii limfogranulematoza.