Fletcher factor deficiency (Report of a new case).
A new case of Fletcher factor (prekallikrein) deficiency is described. The patient did not have any abnormal bleeding tendency, but showed defective intrinsic thromboplastin production and reduced fibrinolytic system activity; he had no factor VIII, IX, XI and XII deficiencies. His plasma did not contain any detectable prekallikrein levels.
D000328:Adult; D001778:Blood Coagulation Disorders / Q000503:physiopathology*; D001779:Blood Coagulation Factors / Q000032:analysis; D005342:Fibrinolysis; D006801:Humans; D007610:Kallikreins; D007616:Kaolin; D008297:Male; D010314:Partial Thromboplastin Time; D011288:Prekallikrein
D001779:Blood Coagulation Factors; D007616:Kaolin; D011288:Prekallikrein; D007610:Kallikreins