title: [Antitryptic and antichymotryptic activity of salivary gland secretions and intestinal contents of the medical leech Hirudo medicinalis].
abstract: Antithrombin, antitryptic and antichymotryptic activities were studied in various tissues of medical leech Hirudo medicinalis. Maximal antithrombin and antitryptic activities were found in secretion products of salivary glands. Intestinal chyme exhibited distinct antichymotryptic activity. The antichymotrypsin activity correlated with antithrombin activity in hirudin preparations, obtained after isoelectrofocusing and free of bdellines. A preparation of "pseudohirudin" exhibited neither antitryptic nor antichymotryptic activities.
mesh_terms: D000818:Animals; D000991:Antithrombins / Q000378:metabolism; D002918:Chymotrypsin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006629:Hirudins / Q000031:analogs & derivatives / Q000032:analysis; D007419:Intestinal Secretions / Q000032:analysis; D007865:Leeches / Q000378:metabolism*; D012469:Salivary Glands / Q000378:metabolism; D014361:Trypsin Inhibitors / Q000378:metabolism*; D000514:alpha 1-Antichymotrypsin
chemical_list: D000991:Antithrombins; D006629:Hirudins; D014361:Trypsin Inhibitors; D000514:alpha 1-Antichymotrypsin; C024670:pseudohirudin; D002918:Chymotrypsin
vernacular_title: Antitripticheskaia i antikhimotripticheskaia aktivnost' sekreta sliunnykh zhelez i soderzhimogo kishechnika meditsinskikh piiavok Hirudo medicinalis.