Sensitivity and optimal performance in steroid receptor analysis.
The application of various mathematical models for the identification of binding parameters in steroid receptor studies is discussed. In contrast to the usual statistical error considerations a deterministic error analysis based on the Euclidian norm and condition numbers is included. The predicted sensitivity behaviour with respect to data scattering is in good agreement with the experimental results.
D000818:Animals; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D011960:Receptors, Estrogen / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D011987:Receptors, Steroid / Q000378:metabolism*; D012984:Software
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D011987:Receptors, Steroid