Disappearance of the decrease in biting behavior induced by clenbuterol, a beta-adrenergic agonist, after chronic administration.
The beta-adrenergic agonist clenbuterol decreased interest in food in starved mice, 30 minutes after administration. This effect disappeared after repeated treatment with clenbuterol (0.25 mg/kg, twice daily). Three chronic injections were sufficient to prevent the effect of an acute dose of clenbuterol (0.125 mg/kg) up to 45 hours after treatment.
D000374:Aggression / Q000187:drug effects*; D000818:Animals; D002976:Clenbuterol / Q000008:administration & dosage / Q000494:pharmacology*; D004361:Drug Tolerance; D004983:Ethanolamines / Q000494:pharmacology*; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice
D004983:Ethanolamines; D002976:Clenbuterol