[Angiosarcoma of the breast].
Since angiosarcoma of the breast was first reported in 1907 fewer than one hundred cases have been reported. They are primary malignant vascular mesenchymal tumors occurring in young females. Their prognosis is very bad. We report here six new cases treated at the Institut Curie between 1972-1983. The mean age was 33, range 27-40. One tumor was a low grade one and the five others of breast, were high grade tumors. We carried out four amputations three associated with radiotherapy and/or chemotherapy and the fourth one did not received adjuvant treatment. In the two others cases the diagnosis was made when the patients were already suffering from polymetastatic disease. The mean survival was 17 months, the range 5-44 months. Recent reviews of the pathologic material made it possible to differentiate three grades in these tumors. The prognosis was correlated to the degree of differentiation. Recently hormonal receptors have been described in soft tissue sarcomas. The value of levels of these receptors in breast angiosarcoma Is discussed.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006394:Hemangiosarcoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008408:Mastectomy; D011379:Prognosis
Angiosarcomes du sein.