Serum and urinary arginine-esterase activity in paediatric kidney diseases.
Serum and urinary kallikrein activities were determined from the arginine-esterase activities in various groups of kidney diseases and were compared with urinary beta-glucuronidase excretion, urinary output, urinary protein content and creatinine clearance. Serum arginine-esterase activity was significantly augmented in the active stage of diffuse renal diseases but was not related to the severity of parenchymal damage. The values improved during remission; the enzyme activity in chronic uraemic patient was as low as in the control sera. There was a positive correlation between urinary output and serum arginine-esterase activity, and consequently serum kallikrein might have an enhancing effect on diuresis.
D000293:Adolescent; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D005921:Glomerulonephritis / Q000201:enzymology; D005966:Glucuronidase / Q000652:urine; D006801:Humans; D007610:Kallikreins / Q000378:metabolism; D007674:Kidney Diseases / Q000201:enzymology* / Q000378:metabolism; D009404:Nephrotic Syndrome / Q000201:enzymology; D011704:Pyelonephritis / Q000201:enzymology; D014511:Uremia / Q000201:enzymology
C019724:arginine esterase; D002265:Carboxylic Ester Hydrolases; D005966:Glucuronidase; D007610:Kallikreins