Cytoplasmic filaments in fetal and neonatal pig testis.
Leydig cells in developing fetal pig testis contained during the fetal regressive phase large accumulations of intermediate filaments. Before and after this period these filaments were arranged in a criss-cross fashion. In the pig as well as in the dog testis these filaments have been characterized as vimentin. Within the vimentin aggregates occasionally a weak positive actin reaction was seen in pig but not in dog Leydig cells. Microfilaments were hardly observed. Most Sertoli cells contained a layer of actin microfilaments close to the basal cell membrane. In the lower cell compartment and around the nucleus (intermediate) vimentin filaments could be observed in a criss-cross configuration.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D003599:Cytoskeleton / Q000648:ultrastructure*; D007985:Leydig Cells / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D013552:Swine; D013737:Testis / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure*