title: Clonorchiasis: treatment with praziquantel in 50 cases.
abstract: Of 50 patients infected with Clonorchis sinensis, 3 groups were formed and treated with different doses of praziquantel (2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a] isoquinolin- 4-one). 24 patients out of 50 were followed up for 3 months and another 10 for 6 months. It is evident that this single-day treatment is effective and satisfactory. In 5 patients with glucose-6-phosphate dehydrogenase deficiency no haemolysis occurred.
mesh_terms: D003003:Clonorchiasis / Q000188:drug therapy* / Q000469:parasitology; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D010270:Parasite Egg Count; D011223:Praziquantel / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D007546:Isoquinolines; D011223:Praziquantel