Apomorphine-induced stereotypy: function of age and rearing environment.
Rats of different age groups ("young" vs. "old"), reared in isolation and social groups were tested for differences in apomorphine-induced stereotypy. Sensitivity to apomorphine (2 mg/kg SC) was found to be a function of an interaction between rearing environment and age. The "younger" isolated animals displayed greater stereotypy than group-reared and "older" isolated animals. Rearing environment and age, as main factors, did not have significant influence on drug-induced stereotypy.
D000375:Aging; D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D004777:Environment; D006801:Humans; D008297:Male; D051381:Rats; D012934:Social Isolation; D013239:Stereotyped Behavior / Q000187:drug effects*
D001058:Apomorphine