[Regional cerebral blood flow and neurological conditions in patients with surgically treated hypertensive intracerebral hemorrhage].
Regional cerebral blood flow (rCBF) was measured in 49 patients with surgically treated hypertensive intracerebral hemorrhage (putaminal hemorrhage 27: thalamic hemorrhage 22). The hematoma evacuation was performed within 14 days after the hemorrhage. For the measurement of rCBF, the intracarotid xenon-133 injection method was used. Two rCBF studies were performed on all patients, the first giving the resting state of the brain perfusion, the second after Prostaglandin E1 (PGE) administration into the internal carotid artery 10 minute after the first study. (PGE was administered 10 micrograms in 5 minutes.) In all patients blood pressure and arterial carbon dioxide tension were examined before and after each CBF study. The evaluation was made by comparing the rCBF maps obtained before and after PGE administration. (A rate of rCBF increase was calculated by dividing each rCBF value obtained after PGE administration by each rCBF value obtained before PGE administration (control value), and the ratio was multiplied by 100.) The PGE-induced reaction patterns were divided into four; the first is the diffuse increase pattern, characterized by a diffuse increase of rCBF values in the hematoma-evacuated area and the surrounding brain; the second is the diffuse decrease pattern, characterized by a global decrease of rCBF values in the hematoma-evacuated area and the surrounding brain; the third is the pattern of intracerebral steal effect, characterized by a decrease of rCBF in the hematoma-evacuated area and an increase of rCBF values in the surrounding brain; and the fourth is the pattern of inverse cerebral steal effect, characterized by an increase of rCBF in the hematoma-evacuated area and a decrease of rCBF in the surrounding brain.(ABSTRACT TRUNCATED AT 250 WORDS)
D000328:Adult; D000368:Aged; D000527:Alprostadil; D001794:Blood Pressure / Q000187:drug effects; D002543:Cerebral Hemorrhage / Q000503:physiopathology* / Q000601:surgery; D002557:Cerebrospinal Fluid Shunts; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004322:Drainage; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011458:Prostaglandins E / Q000494:pharmacology
D011458:Prostaglandins E; D000527:Alprostadil