title: A survey of adverse effects associated with ivermectin use in Louisiana horses.
abstract: In a survey of 13 Louisiana equine practices, it was determined that 366 of 3,316 horses developed adverse reactions following use of ivermectin, with 3 of the horses having more than 1 reaction. Almost all of the reactions were of minor to moderate concern; however, 1 death was reported. Three hundred and thirty-two (91% of all reactions) were reported as ventral midline pruritus or edema (10% of all doses). Fifteen (0.45%) were transient injection site swelling and/or stiffness. Eleven horses (0.33%) developed limb edema. Eyelid edema was reported in 4 horses (0.12%). Two horses (0.06%) had fever. Rate and depth of respiration was increased in 1 horse (0.03%). One horse (0.03%) became disoriented. Three horses (0.09%) developed signs of colic. One horse (0.03%) died a few minutes after injection, and 1 horse (0.03%) became depressed. The survey covered the period from March to August of 1983.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000009:adverse effects*; D004487:Edema / Q000139:chemically induced / Q000662:veterinary*; D006734:Horse Diseases / Q000139:chemically induced*; D006736:Horses; D007559:Ivermectin; D007783:Lactones / Q000009:adverse effects*; D008145:Louisiana; D011537:Pruritus / Q000139:chemically induced / Q000662:veterinary
chemical_list: D000871:Anthelmintics; D007783:Lactones; D007559:Ivermectin