Choriocarcinoma xenografts in the nude rat.
The transplantation of a human choriocarcinoma xenograft (CC3) in the nude rat is reported. The tumours grew progressively for up to 5 weeks but subsequently regressed. Our preliminary results suggest that regression of the tumours appears to be dependent on host age.
D000367:Age Factors; D000818:Animals; D002822:Choriocarcinoma / Q000276:immunology / Q000473:pathology*; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D006801:Humans; D009365:Neoplasm Regression, Spontaneous; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology / Q000473:pathology; D011247:Pregnancy; D051381:Rats; D011922:Rats, Mutant Strains; D014183:Transplantation, Heterologous; D014594:Uterine Neoplasms / Q000276:immunology / Q000473:pathology*