Colonic pseudo-obstruction: a late complication of jejunoileal bypass.
Three cases of jejunoileal bypass, performed for morbid obesity, were complicated 3 to 4 years later by symptoms of colonic pseudo-obstruction. In each case the colon was enlarged, dilated and atonic with no demonstrable organic obstruction. In the patient with end-to-side anastomosis, the entire colon was dilated. In the two patients with end-to-end anastomosis, the dilatation affected the colon distal to the anastomosis with the defunctionalized small bowel. Treatment with antianaerobic antibiotics resulted in a dramatic disappearance of symptoms. It is suggested that bacterial overgrowth in the defunctionalized loops of small bowel may play an important role in the development of colonic pseudo-obstruction as a late complication of jejunoileal bypass.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003108:Colonic Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007415:Intestinal Obstruction / Q000209:etiology*; D007418:Intestinal Pseudo-Obstruction / Q000209:etiology*; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D011183:Postoperative Complications
D000900:Anti-Bacterial Agents