title: [Clinical studies of an ampicillin suppository (KS-R1) in pediatrics].
abstract: Ampicillin suppository (KS-R1) was given to 67 childish patients with acute febrile upper respiratory infection and 1 patient with urinary tract infection at dose level of 29-63 mg/kg/day divided into 3-4. Twenty-five strains of pathogens were isolated in 23 patients out of 68 before the administration of KS-R1, and 19 strains (76.0%) among them were eradicated by KS-R1. Clinically, all cases were effective. The clinical efficacy alone was determined in other 44 patients with acute febrile upper respiratory infection and 1 patient with urinary tract infection, and only 3 cases among them showed poor effect with KS-R1 treatment. No side effects were observed.
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D000667:Ampicillin / Q000008:administration & dosage* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010403:Penicillin Resistance; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D013488:Suppositories
chemical_list: D013488:Suppositories; D000667:Ampicillin