title: Amoebic meningitis also occurs in NSW.
abstract: The clinical, pathological and laboratory findings of a 3-year-old boy with proven primary amoebic meningo-encephalitis are described. The EEG showed changes of acute cortical necrosis lateralised to one temporal lobe and was similar to that described with Herpes simplex encephalitis. CT scan findings indicated acute cortical inflammation and basal arachnoiditis. The disease should be suspected in the context of acute pyogenic meningitis when no organisms are isolated. Treatment with amphotericin-B, miconazole and rifampicin has been effective in previously reported patients.
mesh_terms: D000562:Amebiasis / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D001315:Australia; D002675:Child, Preschool; D004569:Electroencephalography; D006801:Humans; D008297:Male; D008578:Meninges / Q000473:pathology; D008581:Meningitis / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology