[Features of the structure of the mesenteric and tracheobronchial lymph nodes in rat offspring after exposure to tetracycline].
Ante- and postnatal development of anatomical structures and cells of lymphatic nodes has been studied in rat offspring subjected to tetracycline effect during placentation and organogenesis (the 8th-14th days) and during fetogenesis (the 15th-20th days). Tetracycline injection during the 8th-14th days of embryogenesis results in certain disturbances of the nodular structure formations, inhibition of lympho- and plasmo-cytopoesis against the background of a sharp increase in number of basophilic granulocytes and tissue basophils. The antibiotic effect on the 15th-20th days of embryogenesis does not disturb the lymph node formation, but produces an increasing number of lymphocytes, plasmocytes, macrophages, eosinophilic granulocytes and tissue basophils in them.
D000818:Animals; D001980:Bronchi; D005260:Female; D005865:Gestational Age; D008198:Lymph Nodes / Q000196:embryology; D008206:Lymphatic Diseases / Q000139:chemically induced / Q000196:embryology; D008431:Maternal-Fetal Exchange; D008643:Mesentery; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013752:Tetracycline / Q000633:toxicity*; D014132:Trachea
D013752:Tetracycline
Osobennosti stroeniia bryzheechnykh i trakheobronkhial'nykh limfaticheskikh uzlov u potomstva krys posle vozdeĭstviia tetratsiklina.