title: [Analysis of the practical significance of amino acid requirements in human nutrition].
abstract: The objective of this paper was to analyze the usefulness of the actual figures of amino acid requirements in human nutrition. In order to establish the amino acid pattern, the amino acid requirements are related to the safe level of protein intake. Since this safe level has been modified, the amino acid patterns also change, unless there is also a similar modification in the amino acid requirements. Consequently, the use of an amino acid pattern similar to the amino acid composition of a high-quality protein, as is the case of milk, is suggested. Another concept which is necessary to emphasize is that the amino acid pattern proposed for normal nutrition can not be applied to different pathological states. This statement is exemplified by the dietetic treatment of hepatic coma. The mean amino acids intake in physiological studies oriented to determine protein requirements, as well as those observed in low socioeconomic level population groups, are higher than the requirements. These observations can be explained by the methodology used in their determinations, with a previous adaptation period which produces a decrease in the tissue mass of a high percentage of individuals. It is concluded that to obtain a rational application of the amino acids requirements, determined by physiological methods, it is necessary to perform a critical analysis of the figures proposed by the Committees, and adapt them to local prevailing conditions.
mesh_terms: D000328:Adult; D000601:Amino Acids, Essential / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004032:Diet / Q000592:standards*; D004044:Dietary Proteins / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D009751:Nutritional Requirements
chemical_list: D000601:Amino Acids, Essential; D004044:Dietary Proteins
vernacular_title: Análisis del significado práctico de los requerimientos de amino ácidos en la nutrición humana.