Thymosin beta 11: a peptide from trout liver homologous to thymosin beta 4.
A peptide containing 41 amino acid residues has been isolated from trout liver and identified as a member of the beta-thymosin family. Sequence analysis shows it to be 78% homologous to thymosin beta 4, which is the peptide present in the thymus and other tissues of higher vertebrates, including, as reported here, livers of a species of reptile. Thymosin beta 11 appears to replace the more prevalent thymosin beta 4 in at least two species of bony fish, and represents the sixth structurally characterized member of this widely distributed family of peptides.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D008099:Liver / Q000032:analysis*; D012487:Salmonidae / Q000378:metabolism*; D013947:Thymosin / Q000031:analogs & derivatives* / Q000302:isolation & purification; D014337:Trout / Q000378:metabolism*; D000099201:Thymosin beta(4)
D000596:Amino Acids; D013947:Thymosin; D000099201:Thymosin beta(4); C042685:thymosin beta(11)