title: Tympanosclerosis of the ear drum in children.
abstract: Tympanosclerosis of the ear drum in children is associated with secretory otitis media. The tympanosclerotic changes affect the pars tensa and seem to be a dynamic process of new formation together with regress and restoration to normal tissue. Our study includes 90 cleft palate children followed for 7.8 years with a total of 2068 examinations. During the observation period 59% of the ear drums were affected by tympanosclerosis, while only 42% had tympanosclerosis at the last examination. The tympanosclerotic lesion of the ear drum disappeared completely in 30%, seemed stable in 40% and tended to grow steadily in 30% of the ear drums affected. The pathogenesis of tympanosclerosis is not clear, although the inflammation known to exist in secretory otitis media probably plays an important part.
mesh_terms: D000293:Adolescent; D000375:Aging; D002648:Child; D002675:Child, Preschool; D002972:Cleft Palate / Q000150:complications; D004427:Ear Diseases / Q000209:etiology; D004432:Ear, Middle / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D010034:Otitis Media with Effusion / Q000150:complications; D012598:Sclerosis; D014432:Tympanic Membrane / Q000473:pathology* / Q000648:ultrastructure