Bacterial production of 7-formamidocephalosporins. Isolation and structure determination.
Two new 7-formamidocephalosporins have been isolated as their acetyl derivatives (SQ 28,516 and SQ 28,517) from fermentations of a Flavobacterium sp. SC 12,154. Structure 1 was deduced for SQ 28,516 from its spectroscopic properties while structure 2 was proposed for SQ 28,517. SQ 28,516 exhibits weak antibacterial activity.
D002511:Cephalosporins / Q000302:isolation & purification*; D005285:Fermentation; D005417:Flavobacterium / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight
D002511:Cephalosporins; C042545:SQ 28516; C042546:SQ 28517