title: Penitricin, a new class of antibiotic produced by Penicillium aculeatum. II. Isolation and characterization.
abstract: A novel antibiotic, penitricin, Ro 09-0804, has been produced in the culture filtrate of Penicillium aculeatum NR 5165. This antibiotic was purified by repeated extraction of culture filtrate with 1-butanol, and passage of the crude extracts through Sephadex G-10, followed by HPLC (Shodex Ionpak S-801). Physico-chemical characterization was made on penitricin, while two open-ringed penitricins B and C co-produced by the producer strain were also identified.
mesh_terms: D000447:Aldehydes / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D002072:Butylene Glycols / Q000302:isolation & purification*; D003521:Cyclopropanes / Q000302:isolation & purification; D010407:Penicillium / Q000032:analysis; D013055:Spectrophotometry, Infrared
chemical_list: D000447:Aldehydes; D000900:Anti-Bacterial Agents; D002072:Butylene Glycols; D003521:Cyclopropanes; C042544:penitricin C; C042543:penitricin B; C042542:penitricin