The rapid separation and assay of previously unreported plasminogen activators in human euglobulin fractions. The effect of venous occlusion.
Euglobulins were prepared from pre and post venous occlusion plasma by acidification and dilution at pH 5.9. It is shown by isoelectrofocussing that there are several plasminogen activators with differing pI's in euglobulin fractions. Activators with pI's 8.9/9.0, and 9.4 are the major activators responsible for the increase in post occlusion plasminogen activator activity. Fibrin was necessary for the induction of the vascular occlusion response.
D003250:Constriction; D005342:Fibrinolysis; D006801:Humans; D007526:Isoelectric Point; D010960:Plasminogen Activators / Q000302:isolation & purification*; D012712:Serum Globulins / Q000032:analysis*; D014680:Veins
D012712:Serum Globulins; D010960:Plasminogen Activators