title: [Potential for dependence of analgesics and psychopharmaceuticals].
abstract: The dependence liability of analgesic and psychotropic drugs as assessed in animal experiments is described. It is demonstrated that the abuse liability of a given drug does not only depend on its pharmacological or psychopharmacological profile of actions. The abuse liability of a drug is, however, greatly influenced by environmental variables, motivation to self-administration of a drug as well as previous drug exposure. Correlations between dependent behavior of animals and dependent behavior of men are discussed.
mesh_terms: D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D001241:Aspirin / Q000494:pharmacology; D001463:Barbiturates / Q000494:pharmacology; D003216:Conditioning, Operant / Q000187:drug effects; D004558:Electric Stimulation; D006801:Humans; D009020:Morphine / Q000037:antagonists & inhibitors; D009269:Nalorphine / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology; D009294:Narcotics / Q000494:pharmacology; D010423:Pentazocine / Q000494:pharmacology; D011619:Psychotropic Drugs; D051381:Rats; D012646:Self Administration; D019966:Substance-Related Disorders / Q000503:physiopathology / Q000523:psychology*
chemical_list: D000700:Analgesics; D001463:Barbiturates; D009292:Narcotic Antagonists; D009294:Narcotics; D011619:Psychotropic Drugs; D009020:Morphine; D001241:Aspirin; D010423:Pentazocine; D009269:Nalorphine
vernacular_title: Abhängigkeitspotential von Analgetika und Psychopharmaka.