Acute tissue irritation of polysulfide rubber impression materials.
The acute toxic reaction to 14 polysulfide rubber impression materials certified by the ADA was measured after injection into the oral mucosa of two baboons for 48 h, and the inflammatory response was evaluated quantitatively. Two materials were significantly more toxic than the others. Although light-bodied materials were less toxic and contained less lead, toxicity was not strongly related to lead content.
D000818:Animals; D003760:Dental Impression Materials / Q000009:adverse effects* / Q000032:analysis; D007267:Injections; D007509:Irritants; D007854:Lead / Q000009:adverse effects / Q000032:analysis; D008297:Male; D009061:Mouth Mucosa / Q000187:drug effects*; D010215:Papio; D012408:Rubber / Q000009:adverse effects*; D013440:Sulfides / Q000009:adverse effects*
D003760:Dental Impression Materials; D007509:Irritants; D013440:Sulfides; D007854:Lead; C016143:polysulfide rubber; D012408:Rubber