Genetic aspects of vulvar lichen sclerosus.
Thirteen instances of familial lichen sclerosus have been recorded in the literature. This report documents the disease in two additional families and adds genetic data on their HLA characteristics. The relationship of these factors to a possible autoimmune mechanism for the disease is discussed.
D000328:Adult; D000368:Aged; D005260:Female; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D012871:Skin Diseases / Q000235:genetics*; D014845:Vulvar Diseases / Q000235:genetics*
D005819:Genetic Markers; D006680:HLA Antigens