Associated abnormalities of chromosomes 1, 5, and 11 in dysmyelopoietic syndromes.
Two patients with dysmyelopoietic syndrome presented the same cytogenetic pattern in their bone marrow cells, i.e., trisomy of chromosomes #1 and #11, and terminal deletion of chromosome #5 (q13-q14). Two similar cases have been described in the literature. It is suggested that this cytogenetic pattern could be a nonrandom event.
D000368:Aged; D002872:Chromosome Deletion; D002900:Chromosomes, Human, 1-3; D002905:Chromosomes, Human, 4-5; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics; D008297:Male; D010198:Pancytopenia / Q000235:genetics*; D014314:Trisomy