Effects of dimethyl sulfoxide and acupuncture on the cardiovascular system of dogs.
The intravenous administration of dimethyl sulfoxide (100 mg/kg) resulted in a significant increase in cardiac output, stroke volume, central venous pressure, and a significant decrease in heart rate. Acupuncture by electrocautery at Jen Chung (Go-26) produced a significant increase in cardiac output, stroke volume, heart rate, mean arterial pressure, and pulse pressure and a significant decrease in total peripheral resistance in dogs under 0.75% halothane anesthesia. Both DMSO and acupuncture elicit an analgesic effect and enhance cardiovascular function as exemplified by an increase in the cardiac output.
D015670:Acupuncture Therapy; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology*; D004285:Dogs; D006339:Heart Rate / Q000187:drug effects; D011674:Pulse / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects
D004121:Dimethyl Sulfoxide