[Clinical application of alkaline phosphatase bone-isoenzyme determination with acetate foil].
Clinical application of alkaline phosphatase bone isoenzyme determination using acetate foil is investigated in patients with known underlying disease and is compared with diagnostic evaluation of 112 bone-scans. The separation of alkaline phosphatase isoenzymes proves a valuable diagnostic support of bone scintigraphy. Isoenzyme determination moreover reveals primary and secondary bone changes in early stages of the disease and also offers the possibility of quantitative follow-ups.
D000230:Adenocarcinoma / Q000175:diagnosis; D000469:Alkaline Phosphatase / Q000378:metabolism*; D001847:Bone Diseases / Q000175:diagnosis*; D001859:Bone Neoplasms / Q000175:diagnosis*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000201:enzymology*; D001943:Breast Neoplasms / Q000175:diagnosis; D002779:Cholestasis / Q000175:diagnosis; D004586:Electrophoresis; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007592:Joint Diseases / Q000175:diagnosis; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis; D011471:Prostatic Neoplasms / Q000175:diagnosis; D011877:Radionuclide Imaging
D007527:Isoenzymes; D000469:Alkaline Phosphatase
Die klinische Einsatzmöglichkeit der Alkalische-Phosphatase-Knochenisoenzymbestimmung mittels Azetatfolie.