Iohexol compared with diatrizoate in pediatric urography.
Iohexol (300 mg I/ml) was compared with meglumine-Na diatrizoate (290 mg I/ml) in a randomized, single blind, parallel investigation in pediatric urography. Urography with iohexol was performed in 25 infants and with diatrizoate in 26. No changes of clinical importance were observed in blood or urine. No patient reactions were observed in the iohexol group, while 3 patients in the diatrizoate group had reactions assessed to be caused by the contrast medium. Iohexol gave somewhat better diagnostic information than diatrizoate.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media / Q000633:toxicity; D003973:Diatrizoate / Q000633:toxicity; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007223:Infant; D007463:Iodobenzoates; D007472:Iohexol; D008297:Male; D009325:Nausea / Q000139:chemically induced; D011537:Pruritus / Q000139:chemically induced; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000633:toxicity; D014567:Urography; D014839:Vomiting / Q000139:chemically induced
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D007472:Iohexol