Epidemiology of breast cancer and hair dyes.
In a case-control study of 401 breast cancer cases and 625 age-matched controls, the possible etiologic role of hair dye usage was investigated. No association was found between hair dye use and breast cancer (odds ratio = 1.02; 95% confidence interval = 0.77-1.32) or any factors affecting dosage, frequency, duration, type, or color of hair dye. Important confounders of hair dye use included religion and smoking status. When stratified by 10-year age groups, there was no appreciable trend in risk status between case and referent populations. No dose-response relationship (frequency X duration X shade X type of dye used) was found, even after controlling for factors affecting hair dye use. A multiple logistic regression analysis supported the absence of this relationship.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology*; D003710:Demography; D005260:Female; D006202:Hair Dyes / Q000633:toxicity*; D006203:Hair Preparations / Q000633:toxicity*; D006801:Humans; D008875:Middle Aged; D012306:Risk; D013997:Time Factors; D014481:United States
D006202:Hair Dyes; D006203:Hair Preparations