Corneal thickness changes associated with daily and extended contact lens wear.
Human corneal thickness was measured during daily wear of hydrogel contact lenses and then during the initial 2 weeks extended wear of hyper-thin (0.035 mm), low water content (38.6%), hydrogel lenses (polymacon). Results show that subjects wearing standard thickness (0.12 mm) and ultra-thin (0.07 mm) hydrogel lenses of low water content for daily wear will exhibit a diurnal swelling of the cornea. Subjects wearing hyper-thin (0.035 mm) low minus power hydrogel contact lenses of low water content for extended wear will exhibit overnight (closed eye) swelling of the cornea followed by a deswelling throughout the day (open eye). The degree of swelling and deswelling can vary greatly among individual subjects.
D002940:Circadian Rhythm; D003262:Contact Lenses, Extended-Wear / Q000592:standards*; D003263:Contact Lenses, Hydrophilic / Q000592:standards*; D003315:Cornea / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D012890:Sleep