Monocusp aortic valve replacement in dogs: an experimental model.
Aortic valve replacement using human allograft valves is a well established procedure, following which histological evidence of a host-graft interaction is seen. This varies in intensity, depending on the types of sterilizing and storage agents to which the allograft is exposed prior to insertion. A canine experimental model which enables study of these tissue ingrowth patterns in variously treated allografts has been devised. The technique is described in detail.
D000818:Animals; D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis; D004285:Dogs; D004696:Endocarditis / Q000209:etiology; D006087:Graft vs Host Reaction; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D008955:Models, Cardiovascular; D014021:Tissue Preservation