[Clinical experience with cefmetazole in the urological field].
The clinical effectiveness of Cefmetazole, a new cephamycin antibiotic, was studied in 13 cases of complicated urinary tract infection and in 3 cases of acute simple pyelonephritis. The drug was administrated, in 2 or 4 g doses twice a day, by intravenous drip infusion, for 5 to 10 days. The overall clinical effectiveness rate, based on the UTI efficacy evaluation, was 92% for complicated urinary tract infection and 100% for acute simple pyelonephritis. Among 18 strains isolated, 14 strains were eradicated and 4 strains were replaced. The bacteriological efficacy was 100%. No adverse reaction was noted. Cefmetazole was suggested to be a useful antibiotic for the treatment of urinary tract infections.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001419:Bacteria / Q000187:drug effects; D015311:Cefmetazole; D002513:Cephamycins / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D002513:Cephamycins; D015311:Cefmetazole