Chronic myeloid leukaemia presenting as femoral head necrosis.
A 17-year-old male whose initial presentation of chronic myeloid leukaemia (CML) was necrosis of the right femoral head is reported. This is the first case report to our knowledge of CML presenting with such a lesion and is of further interest in that almost all reported cases of destructive bony lesions in this disease have been associated with blast transformation. Our patient in contrast has remained in stable chronic phase for over 30 months.
D000293:Adolescent; D003937:Diagnosis, Differential; D005271:Femur Head Necrosis / Q000175:diagnosis* / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D013163:Splenomegaly / Q000209:etiology