Familial hemifacial microsomia.
Hemifacial microsomia, a relatively distinct clinical form in the Facio-Auriculo-Vertebral Spectrum is generally thought to be a sporadic event, although infrequent familial occurrences have been reported. In this communication, we describe a family with three males and two females in two successive generations affected with hemifacial microsomia. The pedigree is most compatible with autosomal dominant inheritance, although X-linked dominant or multifactorial inheritance cannot be excluded.
D004431:Ear, External / Q000002:abnormalities; D005146:Facial Asymmetry / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000002:abnormalities; D010375:Pedigree