Enamel demineralization by mouthrinses containing different concentrations of sucrose.
Intra-oral enamel demineralization tests, involving rinsing with sucrose solutions (5, 1, 0.5, or 0.3%) at varying frequencies during a 1.5-hour period, showed that demineralization was a function of the total sugar dose (frequency of rinsing times concentration). Two rinses with a 5% solution caused demineralization, nine rinses were needed in the case of a 0.5% solution, and none occurred after nine rinses with a 0.3% solution. Remineralization was also observed and apparently occurred after exhaustion of the sucrose supply.
D000328:Adult; D000368:Aged; D000818:Animals; D002417:Cattle; D003731:Dental Caries / Q000139:chemically induced*; D003743:Dental Enamel / Q000187:drug effects*; D003745:Dental Enamel Permeability / Q000187:drug effects; D006801:Humans; D008297:Male; D009067:Mouthwashes / Q000008:administration & dosage / Q000009:adverse effects*; D013295:Streptococcus mutans / Q000378:metabolism; D013395:Sucrose / Q000008:administration & dosage / Q000009:adverse effects* / Q000378:metabolism
D009067:Mouthwashes; D013395:Sucrose