Optic chiasmal radionecrosis.
Four patients (3 acromegalics, 1 chromophobe adenoma) out of a total of 87 patients with pituitary tumors treated with irradiation are presumed to have developed optic chiasmal radionecrosis. It would appear very difficult, if not impossible, to predict those patients at greatest risk of this complication due to individual variations in sensitivity to radiation.
D000172:Acromegaly / Q000532:radiotherapy; D000238:Adenoma, Chromophobe / Q000532:radiotherapy; D003389:Cranial Nerve Diseases / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009897:Optic Chiasm / Q000528:radiation effects*; D010911:Pituitary Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries; D014786:Vision Disorders / Q000209:etiology