Inhibitory effect of acemetacin, a prodrug of indomethacin, on prostaglandin E2 release from inflamed synovial tissue.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002351:Carrageenan; D015232:Dinoprostone; D007213:Indomethacin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D008297:Male; D011458:Prostaglandins E / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013583:Synovial Membrane / Q000378:metabolism*; D013585:Synovitis / Q000503:physiopathology*
D000893:Anti-Inflammatory Agents; D011458:Prostaglandins E; C026784:acemetacin; D002351:Carrageenan; D015232:Dinoprostone; D007213:Indomethacin