Screening for cystic fibrosis.
During a 12 month period all New Zealand newborns were screened for cystic fibrosis using the Crossley test. Of 49 056 babies tested 522 had a raised blood immunoreactive trypsin level and follow-up testing indicated 19 persistent elevations. Clinical and laboratory studies indicated 14 cases of cystic fibrosis giving an apparent incidence of 1:3500.
D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011863:Radioimmunoassay; D014357:Trypsin / Q000097:blood
D014357:Trypsin