Tissue response to anodyne medicaments.
The tissue-irritating effect of anodyne medicaments was studied via enzyme histochemical evaluation of muscle tissue (screening test) and pulp tissue (usage test). Of the medicaments tested, formocresol was the most irritating, followed by Cresatin, eugenol, and oil of pimenta leaf. The effects of Cresatin, eugenol, and oil of pimenta leaf were not statistically distinguishable.
D000818:Animals; D001672:Biocompatible Materials; D003212:Condiments; D003408:Cresols / Q000494:pharmacology; D003782:Dental Pulp / Q000033:anatomy & histology / Q000187:drug effects / Q000201:enzymology; D004285:Dogs; D005054:Eugenol / Q000494:pharmacology; D005566:Formocresols / Q000494:pharmacology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009132:Muscles / Q000033:anatomy & histology / Q000187:drug effects / Q000201:enzymology; D009821:Oils / Q000494:pharmacology; D009822:Oils, Volatile / Q000494:pharmacology; D011817:Rabbits; D012388:Root Canal Irrigants / Q000494:pharmacology*; D013385:Succinate Dehydrogenase / Q000378:metabolism
D001672:Biocompatible Materials; D003408:Cresols; D005566:Formocresols; D009821:Oils; D009822:Oils, Volatile; D012388:Root Canal Irrigants; C031025:formocresol; D005054:Eugenol; C015088:cresatin; C044113:pimenta oil; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase