NMR imaging of leg tumors.
NMR images of 8 patients with neoplasms of the legs were obtained. Volumetric and/or planar NMR data were acquired using a saturation recovery (SR) approach, incorporating magnetization refocusing. NMR images revealed tumors in all patients and correlated well with the extent seen on CT. SR images with a short interpulse delay (tau) demonstrated a significant decrease in signal intensity (SI) in histologically normal fat (n = 4) and marrow (n = 1) adjacent to tumors, consistent with a prolonged T1. At certain values of tau, tumors on SR images could not be differentiated from normal muscle (tau = 200 msec.) and marrow (tau = 2,100 msec.) by SI alone. Using this sequence with fixed signal refocusing parameters, images representing several values of tau may be required to distinguish tumors from normal structures.
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis*; D005870:Giant Cell Tumors / Q000175:diagnosis; D006801:Humans; D007866:Leg; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*; D014054:Tomography / Q000379:methods*