The efficacy of topical anesthetics in reducing intraoral discomfort.
The purpose of this investigation was to compare the effectiveness of three gels in reducing discomfort due to denture irritation. Forty-five subjects experiencing denture soreness were randomly selected. A double-blind format was used. Two of the gels contained 20% of the known pain reliever, while the third gel contained 10%. An unweighted-means and a least-squares analysis of variance were done for the type of gel and pretreatment pain. The results show that the gels were effective in reducing perceived pain for 66% of the subjects. As a result of the analyses, no significant differences were found between gels.
D000287:Administration, Topical; D001566:Benzocaine / Q000008:administration & dosage / Q000627:therapeutic use*; D003824:Denture, Complete / Q000009:adverse effects; D003832:Denture, Partial, Removable / Q000009:adverse effects; D004311:Double-Blind Method; D005069:Evaluation Studies as Topic; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D011897:Random Allocation; D013280:Stomatitis / Q000188:drug therapy*; D013282:Stomatitis, Denture / Q000188:drug therapy*
D005782:Gels; D001566:Benzocaine