Abnormal hematological indices associated with metastatic choriocarcinoma in a young man.
A 21 year old caucasian male, who was admitted to the medicine service for respiratory problems and hematemesis was ultimately diagnosed as having metastatic choriocarcinoma. Plasma samples were analyzed for prothrombin time (PT), activated partial thromboplastin time (APTT), platelets, and clot activation time for fibrinogen (FIB), and coagulation factors II, V, VII, VIII, X and XII. Abnormal clotting parameters included thrombocytopenia, PT, APTT, FIB, factors II, V, VII, and X. The coagulation abnormalities indicate the patient was in a state of consumption coagulopathy possibly induced by hepatic metastasis of the primary tumor.
D000328:Adult; D001779:Blood Coagulation Factors / Q000032:analysis; D002822:Choriocarcinoma / Q000150:complications / Q000473:pathology / Q000556:secondary*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D006396:Hematemesis / Q000209:etiology; D006400:Hematocrit; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000556:secondary*; D008297:Male; D013736:Testicular Neoplasms / Q000473:pathology*
D001779:Blood Coagulation Factors