Intranuclear undulating membranous structures in cells of a human parosteal osteosarcoma.
Large numbers of paracrystalline undulating membranous structures (UMS) were observed in the nuclei of dense cells in a human parosteal osteosarcoma. The electron-dense walls of the structures were 15-20 nm thick, and circular profiles had an outer diameter of 60-70 nm and an inner diameter of 25-30 nm. The UMS-containing cell nuclei displayed a number of other characteristic features, including vermicellar bodies, large numbers of interchromatin granules, and prominent perichromatin granules. The possible significance of these features is discussed.
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure*; D002843:Chromatin / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005266:Femoral Neoplasms / Q000648:ultrastructure*; D006801:Humans; D007719:Knee Joint; D008297:Male; D008854:Microscopy, Electron; D012516:Osteosarcoma / Q000648:ultrastructure*
D002843:Chromatin