An investigation into the initial discomfort caused by placement of an archwire.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000700:Analgesics / Q000008:administration & dosage; D002648:Child; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008297:Male; D009967:Orthodontic Appliances / Q000009:adverse effects*; D009969:Orthodontic Wires / Q000009:adverse effects*; D010146:Pain / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D012727:Sex Characteristics; D013997:Time Factors
D000700:Analgesics