[Agar cultures of blood forming cells from patients with various forms of hemopoietic dysplasia].
By means of a two-layer agar system the growth-types of blood-forming cells of altogether 47 patients with various forms of the haematopoietic dysplasia were investigated. It could be shown that a hypoplastic and a leukemic growth type as a rule represent a prognostically unfavourable criterion. The probability of a transformation to an acute leukosis is greater in such patients whose blood-forming cells show a leukemic growth in the agar culture. The results of clonization may be used for the differential diagnosis between haematopoietic dysplasia and a number of other diseases. The leukemic growth type was proved in 59% of the patients with haematopoietic dysplasia.
D000741:Anemia, Aplastic / Q000175:diagnosis*; D000756:Anemia, Sideroblastic / Q000175:diagnosis*; D002999:Clone Cells; D003114:Colony-Forming Units Assay; D003937:Diagnosis, Differential; D006410:Hematopoiesis; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis*; D011086:Polycythemia / Q000175:diagnosis*
Agarkulturen blutbildender Zellen von Patienten mit verschiedenen Formen von hämopoetischer Dysplasie.