Phase variation of hyaluronidase-producing peptostreptococci associated with periodontal disease.
Peptostreptococci isolated from diseased periodontal pockets produced large amounts of extracellular hyaluronidase throughout their growth cycle. Phase variants, obtained by re-streaking aged colonies of the wild types, had different colonial morphology and shorter generation times. These variants produced less hyaluronidase, and enzyme production occurred only during the early stationary phase.
D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000378:metabolism*; D010462:Peptostreptococcus / Q000145:classification / Q000166:cytology / Q000201:enzymology*; D010510:Periodontal Diseases / Q000382:microbiology*; D013997:Time Factors
D006821:Hyaluronoglucosaminidase