Clinical experience with the Robin sequence.
In 1980 the results of a trial program of intense non-surgical management on ten consecutive newborn infants admitted with the Robin sequence were reported. The diagnosis of Robin sequence was made based upon the presence of retrognathia and glossoptosis in a newborn infant with or without cleft palate. Upper airway obstruction and feeding difficulties were also present in the post natal and neonatal period. An additional 15 patients were managed using the same protocol. These 25 consecutive patients are divided into two distinct groups. Seventeen have the isolated Robin sequence (IRS) and eight have the Robin sequence as part of a syndrome or associated with multiple congenital anomalies (RSS). A definite trend showing normal growth and development in the isolated Robin sequence is noted.
D000402:Airway Obstruction / Q000517:prevention & control; D001827:Body Height; D001835:Body Weight; D001903:Bottle Feeding / Q000379:methods; D002675:Child, Preschool; D002972:Cleft Palate / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006257:Head / Q000033:anatomy & histology; D006801:Humans; D007223:Infant; D007224:Infant Care; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000503:physiopathology; D008297:Male; D010855:Pierre Robin Syndrome / Q000628:therapy*; D013060:Speech