Chemotaxis and surface glycoproteins of neutrophil granulocytes from patients with juvenile periodontitis.
Neutrophil granulocytes were isolated from the peripheral blood of eight patients with juvenile periodontitis and their healthy controls. The cells were radioactively surface-labelled by the periodate-sodium boro-[3H]-hydride method and their surface glycoproteins studied by polyacrylamide gel electrophoresis and isoelectric focusing. The chemotaxis and chemokinesis were studied against casein. The results indicate that the cells of the patients have normal surface glycoprotein structure and do not show defect in chemotaxis.
D000293:Adolescent; D000328:Adult; D010520:Aggressive Periodontitis / Q000097:blood*; D002364:Caseins; D002634:Chemotaxis, Leukocyte; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008565:Membrane Proteins / Q000097:blood*; D009504:Neutrophils / Q000378:metabolism*; D010510:Periodontal Diseases / Q000097:blood*
D002364:Caseins; D006023:Glycoproteins; D008565:Membrane Proteins