[Antiluteolytic activity of embryos in various animal species].
In mare, sheep and bitch the action of PGF2 alpha have been studied in the early pregnancy. Prostin F2 alpha (Upjohn) and Gabbrostim (Vetem ) are commercial names of PGF2 alpha used at doses which are luteolytic in the non pregnant female. Seric progesterone showed a temporaneous decrease but after four or five days the initial values were restored and none of the experimental females aborted. In the opinion of authors, embryo per se and/or with its adnexa might have interacted blocking the mechanism of luteolysis induced by the administration of PGF2 alpha.
D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects*; D015237:Dinoprost; D004285:Dogs; D004622:Embryo, Mammalian / Q000502:physiology*; D005260:Female; D006736:Horses; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011460:Prostaglandins F / Q000037:antagonists & inhibitors*; D012756:Sheep; D013045:Species Specificity
D011460:Prostaglandins F; D011374:Progesterone; D015237:Dinoprost
Azione antiluteolitica embrionaria in diverse specie animali.