The epidemiological evaluation of drugs.
Depending on the research problem, the epidemiological evaluation of drugs must be based on a combination of research strategies that include experimental methods (controlled trials), and non-experimental methods. Among the latter are correlational studies; spontaneous reporting systems and published case reports; cohort studies; and case-control studies. The spread of computer technology may, by record linkage, facilitate cohort or case-control studies. Comprehensive drug surveillance must be based on the combined use of each research strategy, as appropriate.
D002986:Clinical Trials as Topic / Q000379:methods*; D003201:Computers; D004363:Drug Utilization; D064420:Drug-Related Side Effects and Adverse Reactions; D004812:Epidemiologic Methods; D005069:Evaluation Studies as Topic / Q000379:methods*; D006801:Humans; D007256:Information Systems; D011358:Product Surveillance, Postmarketing / Q000379:methods*; D012107:Research Design