Two new human myeloid cell lines derived from acute promyelocytic leukemia and chronic myelocytic leukemia.
Two new human myeloid cell lines, PL-21 and KCL-22, were established from acute promyelocytic leukemia and chronic myelocytic leukemia, respectively. PL-21 was positive to peroxidase staining and differentiated into mature myeloid cells in vitro. KCL-22 had Ph1 chromosomes and differentiated into granulocytes in vivo.
D000328:Adult; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D002869:Chromosome Aberrations; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000473:pathology*; D008297:Male
D004121:Dimethyl Sulfoxide