The differentiation of malignant lymphoma from anaplastic seminoma in a patient presenting with testicular and jaw swelling.
The histologic differentiation of anaplastic seminoma from lymphoma is often difficult. In the case presented, a malignant lymphoma showing prominent testicular and jaw involvement was initially interpreted as seminoma. The histologic and ultrastructural criteria for differentiation, as well as a comparison of the clinical and epidemiologic characteristics of these tumors, are discussed. A reassessment of previously reported cases of seminoma metastatic to the jaws/antrum, made relative to these data, suggests that in most cases the tumors may actually be lymphomas.
D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000473:pathology*; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000473:pathology*