[Dinoprostone or sulprostone. Comparison of 2 analogs of prostaglandin for the interruption of pregnancy in the 2nd trimester].
We have reviewed a hundred terminations of pregnancy in the second trimester carried out in Geneva, using repeated intra-muscular injections of prostaglandin analogues. We have compared the efficacy and the importance of the side effects of two of these analogues, namely Dinoproston ( Prostin F2 alpha) and Sulproston ( Nalador 500). The induction-delivery interval was identically the same. On the other hand Sulproston provoked fewer cases of diarrhoea (18%) than Dinoproston (69%).
D000019:Abortifacient Agents / Q000494:pharmacology*; D000028:Abortion, Induced; D000328:Adult; D003967:Diarrhea / Q000139:chemically induced; D015232:Dinoprostone / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011458:Prostaglandins E / Q000009:adverse effects / Q000494:pharmacology*; D011459:Prostaglandins E, Synthetic / Q000009:adverse effects / Q000494:pharmacology*; D012189:Retrospective Studies; D014839:Vomiting / Q000139:chemically induced
D000019:Abortifacient Agents; D011458:Prostaglandins E; D011459:Prostaglandins E, Synthetic; C016767:sulprostone; D015232:Dinoprostone
Dinoproston ou sulproston? Comparaison de deux analogues de prostaglandine pour interrompre la grossesse au deuxième trimestre.