Sequential changes in the concentration of prostaglandins and steroids in uterine lymph in sheep during the oestrous cycle.
Sequential samples of uterine lymph were collected from 9 conscious sheep at 4 or 5 h intervals. The mean PGF2 concentration in uterine lymph increased significantly on days 10 and 11 but then fell again, only to increase once more (P less than 0.001) for the 4 days prior to oestrus. PGE2 concentrations in uterine lymph showed no significant changes during the cycle. Lymphatic oestradiol-17 beta concentrations fluctuated throughout the cycle, with peak values considerably higher than those found in peripheral or uterine venous blood.
D000818:Animals; D015237:Dinoprost; D015232:Dinoprostone; D004958:Estradiol / Q000378:metabolism; D004971:Estrus; D005260:Female; D008196:Lymph / Q000378:metabolism*; D011247:Pregnancy; D011374:Progesterone / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism*; D011458:Prostaglandins E / Q000378:metabolism; D011460:Prostaglandins F / Q000378:metabolism; D012756:Sheep / Q000378:metabolism; D013256:Steroids / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*
D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D013256:Steroids; D011374:Progesterone; D004958:Estradiol; D015237:Dinoprost; D015232:Dinoprostone