An age-structured model of pre- and post-vaccination measles transmission.
An infection like measles does not spread uniformly in populations from Europe and North America. Of special importance is a pronounced age-dependency in the contact rates, because of increased infection transmission within schools. Therefore an age-structured epidemiologic model is investigated here, which also pays attention to the fact that children are promoted grade-wise into and out of school. Simulation results are contrasted with pre- and post-vaccination measles data from England and Wales and the model is shown to perform better than previous global mass-action models.
D000367:Age Factors; D001699:Biometry; D002648:Child; D004739:England; D006801:Humans; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission*; D008962:Models, Theoretical; D014611:Vaccination; D014852:Wales