[Effect of the genetic markers Kell(K1), P1, Km(1), Tf(C<B<D), AK and 6-PGD on the outcome of paternity cases].
This statistical analysis of the results of 288 paternity cases is a contribution to the discussion of those blood group systems to be selected for the basis of paternity expertise in the Federal Republic of Germany. When typing 22 blood-group systems in 288 one-man cases, we found exclusions in 101 (35.07%) of them. In only 83 (44.39%) of the 187 cases with nonexclusions did the resulting EM value correspond to the verbal predicate: "paternity practically proved." The results of the systems of factors Kell(K1), Tf(C,B,D), AK and 6-PGD had the smallest rate of exclusion constellations and only inferior influence on the resulting EM values. Replacing them by isoelectric focusing of the systems PGM1, Tf, Gc, Pi and PLG (plasminogen) seems to be reasonable. The factors P1 and Km(1) proved more favorable for the results of paternity cases.
D001789:Blood Group Antigens; D001788:Blood Grouping and Crossmatching; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007525:Isoelectric Focusing; D007626:Kell Blood-Group System; D008297:Male; D010127:P Blood-Group System; D010334:Paternity
D001789:Blood Group Antigens; D005819:Genetic Markers; D007626:Kell Blood-Group System; D010127:P Blood-Group System
Einfluss der Merkmale Kell(K1), P1, Km(1), Tf(C,B,D), AK und 6-PGD auf das Ergebnis von Vaterschaftsgutachten.