Lichen planus: a theory of pathogenesis.
From a continuing study of 108 cases of oral mucosal lichen planus, including so-called drug-induced lichenoid reactions, the response of patients to topical therapy and to drugs implicated in inducing the lichenoid reactions was used to construct a hypothetical model regarding the pathogenesis of the condition. The results were interpreted to indicate that lichen planus is a predetermined condition or diathesis, perhaps genetically based, rather than a simple cause-and-effect disorder.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy / Q000209:etiology*