HLA typing in bartter syndrome.
The mode of inheritance of Bartter syndrome is unclear; however, autosomal recessive inheritance seems likely. A consistent genetic marker of the carrier state likewise remains elusive. HLA typing was done in a family in whom six of 12 sibs have the syndrome. No significant HLA-syndrome linkage was found. This is in contrast to another familial hypokalemic syndrome in which a significant HLA association was found.
D001477:Bartter Syndrome / Q000235:genetics* / Q000276:immunology; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D005819:Genetic Markers; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006801:Humans; D006929:Hyperaldosteronism / Q000235:genetics*; D007008:Hypokalemia / Q000235:genetics; D008297:Male; D010375:Pedigree
D005819:Genetic Markers; D006680:HLA Antigens