Cross-reactions of polysaccharides of fungi, molds, and yeasts in anti-pneumococcal and other antisera.
Cross-reactions of a number of glycans and polysaccharides isolated from fungi, molds, and yeasts in anti-pneumococcal and other antisera are tabulated and discussed insofar as possible with relation to the chemical structures of the cross-precipitating substances and the polysaccharidic antigens giving rise to the reactive antibodies. For example, the slime of Physarum polycephalum precipitated antisera to pneumococcal type 4 and Klebsiella type K1. The polysaccharides of type 4 and K1 contain pyruvic acid in acetal linkage on hydroxyls 2 and 3 of sugars. Therefore, pyruvic acid was looked for and found in Physarum slime. Numerous other relations between chemical structure and immunological specificity are given.
D003429:Cross Reactions; D005658:Fungi / Q000276:immunology*; D007106:Immune Sera; D007709:Klebsiella / Q000276:immunology*; D009174:Mycoplasma / Q000276:immunology*; D010804:Physarum / Q000276:immunology; D011134:Polysaccharides / Q000032:analysis*; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D012475:Salmonella / Q000276:immunology*; D013045:Species Specificity
D007106:Immune Sera; D011134:Polysaccharides; D011135:Polysaccharides, Bacterial