[Thermochemotherapy for malignant melanoma--combination therapy of ACNU and hyperthermia in mice].
The effect of a combination therapy of hyperthermia (43 degrees C, 30 min) and ACNU (10 mg/kg) on B 16 melanoma and C 24 melanoma in vivo was studied. This combination therapy was effective in both melanoma. In C 24 melanoma, remarkably the tumor regression and the partial destruction of the histological structure, were observed.
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000628:therapy*; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D015376:Nimustine; D009607:Nitrosourea Compounds / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000473:pathology / Q000628:therapy*
D000970:Antineoplastic Agents; D009607:Nitrosourea Compounds; D015376:Nimustine