An XX male with a single STS gene dose.
There is substantial evidence that many XX males arise from an X/Y interchange, so that a terminal Xp segment carrying the Xg locus, but not the neighboring steroid sulfatase (STS) locus, is replaced by part of the Y chromosome. We show here that one of the two X chromosomes of an XX male with low intracellular levels of STS does not express the STS gene.
D000818:Animals; D005260:Female; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000502:physiology; D008297:Male; D051379:Mice; D012729:Sex Chromosome Aberrations; D012730:Sex Chromosomes; D043266:Steryl-Sulfatase; D013429:Sulfatases / Q000235:genetics*; D014960:X Chromosome
D013429:Sulfatases; D043266:Steryl-Sulfatase