Phase II study of amsacrine gluconate in refractory leukemia.
Twenty-six adults with refractory leukemia were treated with amsacrine gluconate, a new formulation. There were two complete and two partial remissions. This preparation has no apparent advantage when compared with amsacrine lactate.
D000328:Adult; D000368:Aged; D000609:Aminoacridines / Q000627:therapeutic use*; D000677:Amsacrine; D004341:Drug Evaluation; D005260:Female; D005942:Gluconates; D006801:Humans; D007773:Lactates; D007938:Leukemia / Q000188:drug therapy*; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D007951:Leukemia, Myeloid / Q000188:drug therapy; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
D000609:Aminoacridines; D005942:Gluconates; D007773:Lactates; D000677:Amsacrine