Inhibition of aortic vessel adenosine diphosphate degradation by cadmium and mercury.
The effects of cadmium and mercury on ADP breakdown by vessel walls were investigated. These metals reduce the ADP clearance promoted by arterial tissue. This effect could be attributed to the inhibition of vessel wall ADP-ase enzyme, which plays an important role in the genesis of thrombotic phenomena.
D000244:Adenosine Diphosphate / Q000378:metabolism*; D000818:Animals; D001011:Aorta / Q000378:metabolism; D002104:Cadmium / Q000494:pharmacology*; D008297:Male; D008628:Mercury / Q000494:pharmacology*; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D002104:Cadmium; D000244:Adenosine Diphosphate; D008628:Mercury