[Acute coronary insufficiency during induction of anesthesia following anthracycline chemotherapy].
Cytostatic treatment with anthracyclines lines can lead to acute or chronic myocardial insufficiency. A cumulative dose of less than 500 mg/m2 body surface area can in general be regarded as safe. A case of acute cardio-circulatory insufficiency during induction of anesthesia is described, in which the total cumulative dose did not exceed 250 mg/m2 body surface area. The pathophysiological mechanisms occurring and the diagnostic and therapeutic measures necessary are discussed.
D000758:Anesthesia / Q000009:adverse effects*; D000903:Antibiotics, Antineoplastic; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D009279:Naphthacenes / Q000009:adverse effects
D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes
Akute Herz-Kreislauf-Insuffizienz bei Narkoseeinleitung nach Anthracyclinchemotherapie.