[Blast stage in chronic myeloleukemia--diagnostic and therapeutic problems].
The data are reported from the study on 34 patients with chronic myeloleukosis (ChML), blast stage (BS). The early progress of BS is stressed upon--in 41% of the patients during the first year after making the diagnosis. A juxtaposition is made between some clinical and laboratory indices and the BS progress as well as with life span. Some criteria are presented that could aid the differentiation of BS from a recurrence of ChML. The unsatisfactory results from BS treatment are also stressed upon in spite of the achievements during the last several years. One of the patients was with twice overcome BS, with a duration of the second remission of 8 months.
D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D004796:Clinical Enzyme Tests; D005260:Female; D006098:Granulocytes / Q000201:enzymology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors
D000469:Alkaline Phosphatase
Blasten stadiĭ pri khronichnata mielolevkoza--diagnostichni i terapevtichni problemi.