[Effects of domperidone suppository against adverse reactions in digestive organs induced by cancer chemotherapy].
We examined the effects of domperidone suppository against adverse reactions in digestive organs to antitumor agents. Suppositories containing 60 mg of domperidone were given to 15 patients who were suffering from vomiting and nausea occurring with the use of antitumor agents, and the changes in each digestive symptom were evaluated overall. As a result, 13 patients out of 15 (86.7%) showed improvement of symptoms. There were no adverse reactions to domperidone suppositories.
D000328:Adult; D000368:Aged; D000855:Anorexia / Q000139:chemically induced / Q000188:drug therapy; D000970:Antineoplastic Agents / Q000009:adverse effects*; D004294:Domperidone / Q000627:therapeutic use*; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy*; D013488:Suppositories; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy*
D000970:Antineoplastic Agents; D013488:Suppositories; D004294:Domperidone