Intraocular lens damage to the endothelium of in vitro rabbit corneae: a specular and scanning electron microscopical study.
Under carefully controlled physiological conditions and direct visualisation with the specular microscope, and scanning electronmicroscopical follow up, the effect upon the corneal endothelium of in vitro rabbit corneae of contact with a glass intraocular lens (IOL) and its haptic (Lynell Medical Technology Inc) were compared with the effects of various polymethylmethacrylate (PMMA) IOLs and other materials. The glass IOL and the flat face of its haptic produced no endothelial damage, but the edges of the haptic, rubber and alginate dental impression compound destroyed the cells they touched. The PMMA IOLs caused relatively little damage compared to the previous findings of others. This is tentatively attributed to differences in the test methods.
D000464:Alginates; D000818:Animals; D003315:Cornea / Q000648:ultrastructure; D065306:Corneal Injuries; D004727:Endothelium / Q000648:ultrastructure; D005898:Glass; D007910:Lenses, Intraocular; D008768:Methylmethacrylates; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D012117:Resins, Synthetic; D012408:Rubber
D000464:Alginates; D008768:Methylmethacrylates; D012117:Resins, Synthetic; C029945:polyimide resin; D012408:Rubber