Hürthle-cell tumor arising in the mediastinal ectopic thyroid and diagnosed by fine needle aspiration. Light microscopic and ultrastructural features.
The light microscopic and ultrastructural features of a Hürthle-cell tumor arising in the ectopic mediastinal ectopic thyroid and diagnosed by fine needle aspiration are presented. Although it lacked clear-cut cytologic features of malignancy, the tumor was clinically malignant, having metastasized to the lungs. Hürthle-cell tumors of the thyroid are unpredictable in their biologic behavior, and the absence of clinical and/or pathologic evidence of malignancy at the time of diagnosis is no guarantee of a benign outcome.
D000236:Adenoma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D001707:Biopsy, Needle; D002471:Cell Transformation, Neoplastic / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure