Neuraminidase-activated attachment of Actinomyces naeslundii ATCC 12104 to human buccal epithelial cells.
The attachment of Actinomyces naeslundii ATCC 12104 to human buccal epithelial cells pre-treated with neuraminidase (sialidase) was evaluated. Both commercial clostridial neuraminidase and neuraminidase preparations from the test strain of A. naeslundii enhanced attachment. The results suggest that the A. naeslundii beta-galactoside-seeking ligand involved in hemagglutination and interbacterial coaggregation also mediates one type of binding to human buccal epithelial cells.
D000190:Actinomyces / Q000502:physiology*; D000268:Adhesiveness; D004847:Epithelial Cells; D005697:Galactosides / Q000502:physiology; D006801:Humans; D009061:Mouth Mucosa / Q000166:cytology* / Q000502:physiology; D009439:Neuraminidase / Q000008:administration & dosage / Q000494:pharmacology*
D005697:Galactosides; D009439:Neuraminidase