[Blood pharmacokinetics of fluorine in man after the oral administration of nicomethanol hydrofluoride].
The pharmacokinetic parameters of fluoride have been studied, after a single oral administration to human volunteers of two fluoridated compounds: sodium fluoride, and a new organic fluoride salt, nicomethanol hydrofluoride. The results obtained with these two compounds were very similar, suggesting that no abnormal accumulation of fluoride in the body occurs after using nicomethanol hydrofluoride.
D000284:Administration, Oral; D000328:Adult; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D005260:Female; D005459:Fluorides / Q000378:metabolism / Q000627:therapeutic use*; D005461:Fluorine / Q000097:blood*; D006801:Humans; D006858:Hydrofluoric Acid / Q000378:metabolism / Q000627:therapeutic use; D007700:Kinetics; D008297:Male; D009540:Nicotinyl Alcohol / Q000378:metabolism / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D012969:Sodium Fluoride / Q000378:metabolism / Q000627:therapeutic use
D011725:Pyridines; D005461:Fluorine; D012969:Sodium Fluoride; D009540:Nicotinyl Alcohol; D005459:Fluorides; D006858:Hydrofluoric Acid
Pharmacocinétique sanguine du fluor après administration orale chez l'homme du fluorhydrate de nicométhanol.