Elimination of an anaerobic mycoplasma from a human erythroleukemic cell line, K562.
A human erythroleukemic cell line, K562, contaminated with an anaerobic mycoplasma, was freed of the mycoplasma by passage through nu/nu mice. The mycoplasma-free K562 retains its ability to satisfactorily act as a target cell in the natural cytotoxicity assay.
D000693:Anaerobiosis; D000818:Animals; D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000276:immunology / Q000382:microbiology*; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009175:Mycoplasma Infections / Q000276:immunology / Q000382:microbiology*; D051381:Rats; D011922:Rats, Mutant Strains