Toxoplasmic retinochoroiditis--current concepts in pathogenesis.
The pathogenesis of retinochoroidal destruction associated with infection by Toxoplasma gondii presents a perplexing problem. A murine model of congenital toxoplasmic retinochoroiditis is described in relation to the current concepts regarding the pathogenesis of the disease process in man. It would appear that in this model at least, auto-immune mechanisms may contribute to the inflammatory process.
D000818:Animals; D002825:Chorioretinitis / Q000151:congenital / Q000209:etiology* / Q000473:pathology; D004195:Disease Models, Animal; D051379:Mice; D012160:Retina / Q000473:pathology; D014126:Toxoplasmosis, Ocular / Q000151:congenital / Q000209:etiology* / Q000473:pathology