Effect of phytate and hexadecylamine on the permeability of bovine dental enamel.
The effect of hexadecylamine on the permeability of bovine dental enamel was investigated using a radiochemical diffusion technique. Treatment with an aqueous solution of hexadecylamine reduced the permeability of the enamel by about 20 per cent. Pre-treatment of the enamel with an aqueous solution of phytate followed by hexadecylamine yielded a reduction in permeability of approximately 70 per cent. The observed effects were similar for ionic (86Rb+ and 36Cl-) and non-ionic [( 3H]-sorbitol and [14C]-glycerol) compounds. The strong permeability-reducing effect of the combined phytate-amine treatment may also be anticariogenic.
D000588:Amines / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002712:Chlorides; D003745:Dental Enamel Permeability / Q000187:drug effects*; D004058:Diffusion; D005990:Glycerol / Q000378:metabolism; D006838:Hydrocarbons; D010833:Phytic Acid / Q000494:pharmacology*; D012413:Rubidium / Q000378:metabolism; D013012:Sorbitol / Q000378:metabolism; D013997:Time Factors; D014088:Tooth Permeability / Q000187:drug effects*
D000588:Amines; D002712:Chlorides; D006838:Hydrocarbons; D013012:Sorbitol; D010833:Phytic Acid; D012413:Rubidium; C032710:rubidium chloride; C013553:hexadecylamine; D005990:Glycerol