Plasma fibronectin deficiency during chemotherapy of acute myeloid leukaemia.
Plasma fibronectin was determined using a laser nephelometric method in 10 patients with acute myeloid leukaemia undergoing chemotherapy. There was a continuous fall during the first 3 weeks to about 50% of the normal level. The decrease of fibronectin may contribute to the lowered resistance against infection characteristic of these patients.
D000328:Adult; D000368:Aged; D001996:Bronchopneumonia / Q000209:etiology; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D005260:Female; D005334:Fever / Q000209:etiology; D005353:Fibronectins / Q000032:analysis / Q000172:deficiency*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013866:Thioguanine / Q000008:administration & dosage
D005353:Fibronectins; D003561:Cytarabine; D013866:Thioguanine; D003630:Daunorubicin