Sodium fluoride susceptibilities of suspected periodontopathic bacteria.
Utilizing a blood-based medium, we determined the minimum inhibitory concentrations (MIC's) to sodium fluoride (NaF) of 45 bacterial strains representing 22 oral species. Bacterial susceptibility ranged from 128 micrograms/ml to 2048 micrograms/ml. Of those organisms tested, Actinobacillus actinomycetemcomitans, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga ochracea, and Actinomyces viscosus were susceptible at lower levels of NaF.
D001419:Bacteria / Q000187:drug effects*; D005459:Fluorides / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010510:Periodontal Diseases / Q000382:microbiology*; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000494:pharmacology*
D012969:Sodium Fluoride; D005459:Fluorides