Migration of K562 cells and its inhibition by lymphokines.
Cells of the human myelogenous line K562 migrate from glass capillaries to the glass or plastic surface of culture flasks in the presence of RPMI 1640. Like macrophages they form a halo around the opening of the capillary. Migration is inhibited by lymphokine-containing supernatants from mixed lymphocyte culture (MLC). Concanavalin A stimulated lymphocytes and from several cell lines.
D000818:Animals; D002197:Capillary Action; D002460:Cell Line; D002465:Cell Movement; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D008222:Lymphokines / Q000494:pharmacology*; D008264:Macrophages / Q000166:cytology; D051379:Mice
D008222:Lymphokines