Normal pressure hydrocephalus and Parkinson's disease.
Three patients with normal pressure hydrocephalus and Parkinson's disease are reported. The recognition of this association is important because these two entities require specific therapeutic approaches. The presence of Parkinson's disease does not preclude an excellent response of the hydrocephalus to a shunting procedure. Although several reports of cases with the characteristic clinical manifestations of normal pressure hydrocephalus--progressive dementia, gait difficulty and urinary incontinence--have been published earlier, it was Adams and Hakim who emphasized the clinical triad and the effect of shunting the cerebrospinal fluid as a means of treatment. Messert and Baker stressed that the gait disturbance had a close resemblance to the freezing gait of parkinsonism. We are reporting three patients who had both conditions. Recognition of the existence of both disorders in the same patients is important since appropriate treatment of each of them led to marked improvement of their symptoms.
D000368:Aged; D002557:Cerebrospinal Fluid Shunts; D003131:Combined Modality Therapy; D003704:Dementia / Q000175:diagnosis; D005260:Female; D005684:Gait; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis*; D006850:Hydrocephalus, Normal Pressure / Q000175:diagnosis* / Q000628:therapy; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D010300:Parkinson Disease / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed
D007980:Levodopa