Action of drugs on liposomes with varying charges.
The effects of 12 amphipathic compounds--such as aromatic and aliphatic carboxylic acids, amines, imines, nitrogen-substituted derivatives, and aldehydes--on multilamellar liposomes with varying charges were monitored in biological systems. The stabilization-lysis action of amphipathic compounds on liposomes was influenced by either the electrostatic repulsion or the attraction force between these compounds and liposomes.
D000447:Aldehydes / Q000494:pharmacology; D000588:Amines / Q000494:pharmacology; D002264:Carboxylic Acids / Q000494:pharmacology; D007097:Imines / Q000494:pharmacology; D008081:Liposomes; D009391:Nephelometry and Turbidimetry; D010600:Pharmacology
D000447:Aldehydes; D000588:Amines; D002264:Carboxylic Acids; D007097:Imines; D008081:Liposomes