Radiation-induced cerebral meningioma: a recognizable entity.
The authors retrospectively analyzed the clinical and histopathological findings in 201 patients with intracranial meningiomas operated on in the period 1978 to 1982. Forty-three of the patients (21.4%) had at some previous time received radiation treatment to their scalp, the majority for tinea capitis. The findings in these 43 irradiated patients were compared with those in the 158 non-irradiated patients. Several distinctive clinical and histological features were identified in the irradiated group, which suggest that radiation-induced meningiomas can be defined as a separate nosological subgroup. The use of irradiation in large numbers of children with tinea capitis in the era prior to the availability of griseofulvin may be responsible for a significantly increased incidence of intracranial meningiomas.
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000532:radiotherapy; D008297:Male; D008579:Meningioma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary / Q000209:etiology; D011832:Radiation Injuries / Q000209:etiology*; D012189:Retrospective Studies; D014006:Tinea Capitis / Q000532:radiotherapy