Type III glycogenosis presenting as liver disease in adults with atypical histological features.
Two cases of type III glycogen storage disease are reported in adults; the occurrence of cirrhosis in one case illustrates the potential development of chronic liver disease in this condition. The other was the oldest patient with this condition found in a review of published reports. Electron microscopy of peripheral blood leucocytes to demonstrate excess glycogen was found to be a quick and useful aid to diagnosis. Histology of these adult cases showed a distribution of hepatocyte vacuolation which has not been previously recorded.
D000328:Adult; D000368:Aged; D006003:Glycogen / Q000032:analysis; D006008:Glycogen Storage Disease / Q000150:complications*; D006010:Glycogen Storage Disease Type III / Q000150:complications* / Q000473:pathology; D006801:Humans; D007962:Leukocytes / Q000648:ultrastructure; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male
D006003:Glycogen