An expanded classification of neurotoxic responses based on cellular targets of chemical agents.
We propose an interim classification of neurotoxic substances based on their cellular and sub-cellular targets in the nervous system. These sites are: The neuron (including excitable membrane, transmitter systems, and structural integrity), glial cells and myelin, nervous system vasculature, and muscle.
D000818:Animals; D003711:Demyelinating Diseases / Q000139:chemically induced; D006801:Humans; D066298:In Vitro Techniques; D009186:Myelin Sheath / Q000187:drug effects; D009410:Nerve Degeneration / Q000187:drug effects; D009420:Nervous System / Q000098:blood supply; D009422:Nervous System Diseases / Q000139:chemically induced*; D009457:Neuroglia / Q000187:drug effects; D009468:Neuromuscular Diseases / Q000139:chemically induced; D009474:Neurons / Q000187:drug effects; D009498:Neurotoxins / Q000145:classification*; D014652:Vascular Diseases / Q000139:chemically induced
D009498:Neurotoxins