Surgical separation of the uterus and ovaries with simultaneous cannulation of the uterine vein extends luteal function in sheep.
The insertion of a glass cannula into the uterine branch of the utero-ovarian vein, followed by disconnection of all other tissues between the uterus and the ovary containing the luteal tissue in non-pregnant sheep, was followed by a prolongation of luteal function. A pathway involving uterine venous blood alone is therefore insufficient to explain the transfer of PGF-2 alpha from the uterus to the ipsilateral ovary. We suggest that lymph is also involved.
D000818:Animals; D002404:Catheterization; D003338:Corpus Luteum / Q000502:physiology*; D015237:Dinoprost; D005260:Female; D003341:Luteolysis; D010053:Ovary / Q000098:blood supply* / Q000502:physiology; D011374:Progesterone / Q000097:blood; D011460:Prostaglandins F / Q000502:physiology; D012756:Sheep; D014599:Uterus / Q000098:blood supply* / Q000502:physiology; D014680:Veins
D011460:Prostaglandins F; D011374:Progesterone; D015237:Dinoprost