Increased peripheral catecholamine release in patients with long-standing, untreated essential hypertension.
Both arterial and venous plasma adrenaline and noradrenaline concentrations were elevated in 20 middle-aged men with long-standing, untreated essential hypertension compared to 19 normotensive control men (p less than 0.01). The mean a-v (arterial-venous) difference of adrenaline and v-a difference of noradrenaline were increased in the hypertensive (p less than 0.05) consistent with raised adrenal adrenaline release and release of noradrenaline from the peripheral vascular beds of the forearm.
D001794:Blood Pressure; D004837:Epinephrine / Q000378:metabolism*; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D008875:Middle Aged; D009638:Norepinephrine / Q000378:metabolism*; D013564:Sympathetic Nervous System / Q000378:metabolism*; D013997:Time Factors
D009638:Norepinephrine; D004837:Epinephrine