Abdominal vagotomy does not activate the corpus luteum in rats.
Rats were vagotomized at proestrus and 4 days later serum prolactin and progesterone were determined by radioimmunoassay. The histology of the ovaries and the activity of ovarian delta 5-3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) were also studied. There was no difference between hormone values in sham and vagotomized rats 4 days after surgery. In addition, the ovarian histology and activity of 3 beta-HSD were similar in both sham and vagotomized animals. We conclude that vagotomy at proestrus does not interrupt estrous cycles by activating the corpus luteum.
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D000818:Animals; D003338:Corpus Luteum / Q000201:enzymology / Q000378:metabolism*; D004971:Estrus; D005260:Female; D006651:Histocytochemistry; D011247:Pregnancy; D011374:Progesterone / Q000097:blood*; D011388:Prolactin / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains; D014628:Vagotomy
D011374:Progesterone; D011388:Prolactin; D015096:3-Hydroxysteroid Dehydrogenases