Papilloedema in chronic granulocytic leukaemia.
Five of 75 patients with chronic granulocytic leukaemia seen over a 25 year period had papilloedema at presentation. These patients had unusually high leucocyte counts and the papilloedema may be a manifestation of leucostasis. The fundal abnormalities resolved in all five patients--in four after conventional treatment with busulphan only.
D000328:Adult; D000368:Aged; D002066:Busulfan / Q000627:therapeutic use; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010211:Papilledema / Q000188:drug therapy / Q000209:etiology*
D002066:Busulfan