Topical carbenoxolone sodium in the management of herpes simplex infection.
Topical carbenoxolone was discovered by chance to be a highly effective anti-viral agent and was subsequently used in the management of Herpetic gingivostomatitis and recurrent Herpes labialis. A marked reduction in the healing time and pain associated with these lesions was noted. A discussion of the possible mechanisms of action of carbenoxolone is included.
D000287:Administration, Topical; D002229:Carbenoxolone / Q000008:administration & dosage / Q000627:therapeutic use*; D005881:Gingiva / Q000473:pathology; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives*; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology; D012008:Recurrence; D013283:Stomatitis, Herpetic / Q000188:drug therapy*
D002229:Carbenoxolone; D006034:Glycyrrhetinic Acid