The flow-rate-dependent excretion of ionized calcium in pilocarpine-stimulated human submandibular saliva.
In 10 healthy male subjects the total calcium concentration in submandibular saliva varied between 2.05 +/- 0.12 mmol/l and 2.48 +/- 0.1 mmol/min, and did not show a dependency on the flow rate. The salivary-ionized calcium increased significantly at flow rates between 0.1 and 1.3 ml/min (from 0.74 +/- 0.05 to 1.41 +/- 0.04 mmol/l) and even reached plasma levels.
D002118:Calcium / Q000032:analysis*; D006801:Humans; D008297:Male; D010710:Phosphates / Q000032:analysis; D010862:Pilocarpine / Q000494:pharmacology*; D012463:Saliva / Q000032:analysis / Q000187:drug effects* / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000032:analysis; D012472:Salivation / Q000187:drug effects; D013363:Submandibular Gland / Q000187:drug effects / Q000378:metabolism
D010710:Phosphates; D012471:Salivary Proteins and Peptides; D010862:Pilocarpine; D002118:Calcium