Out-of-phase separation of a G-group chromosome in a woman with chronic myelogenous leukemia.
This report describes a case of out-of-phase (premature) centromere separation of a G-group chromosome in bone marrow cells of a woman with Ph1-negative, chronic myelogenous leukemia. Attention is drawn to the occurrence of this new cytogenetic anomaly in human disease.
D001853:Bone Marrow / Q000503:physiopathology; D002478:Cells, Cultured; D002503:Centromere / Q000502:physiology*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002875:Chromosomes / Q000502:physiology*; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics*; D008875:Middle Aged