The effect of an antibacterial solution on the microflora of human incipient fissure caries.
A technique for collecting various levels of plaque from incipient occlusal fissure caries was used to evaluate the antibacterial properties of a solution containing I2-KI, CuSO4, and ethanol. In comparison with control fissures (n = 6), the treated fissures (n = 9) showed a 98% difference in recoverable bacteria, with the killing of S. mutans, Actinomyces, and lactobacilli appearing to reflect the level of agent penetration.
D000190:Actinomyces / Q000187:drug effects; D000293:Adolescent; D000328:Adult; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D003300:Copper / Q000494:pharmacology*; D003731:Dental Caries / Q000382:microbiology*; D003773:Dental Plaque / Q000382:microbiology; D004202:Disinfectants / Q000494:pharmacology*; D004338:Drug Combinations; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D007455:Iodine / Q000494:pharmacology*; D017613:Iodine Compounds; D007778:Lactobacillus / Q000187:drug effects; D011193:Potassium Iodide / Q000494:pharmacology*; D013295:Streptococcus mutans / Q000187:drug effects
D004202:Disinfectants; D004338:Drug Combinations; D017613:Iodine Compounds; C040266:ORA 5; D011193:Potassium Iodide; D000431:Ethanol; D003300:Copper; D007455:Iodine