[Prostaglandin E2 binding by gastric mucosa cells in the rat].
After incubation of gastric pieces with [3H] prostaglandin E2 (PGE2) the label is accumulating predominantly over the cells situating in the middle third of the gastric glands proper, where mucus-secreting cells are mainly situated. As demonstrate biochemical experiments, [3H] PGE2 combines 5.5 times as intensively with the isolated cells fraction, which consists mainly of mucocytes but not of parietal cells. A suggestion is made that prostaglandin E2 contributes to biosynthesis and mucus secretion in the stomach when it immediately combines with mucocytes.
D000818:Animals; D001345:Autoradiography; D015232:Dinoprostone; D005753:Gastric Mucosa / Q000378:metabolism*; D010295:Parietal Cells, Gastric / Q000378:metabolism; D011458:Prostaglandins E / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D011458:Prostaglandins E; D015232:Dinoprostone
Sviazyvanie prostaglandina E2 kletkami slizistoĭ obolochki zheludka u krys.