Correlation between plasma carcinoembryonic antigen (CEA) and sialyltransferase as tumor marker.
Plasma carcinoembryonic antigen (CEA) and sialyltransferase levels were assayed in 21 cancer patients to correlate them in response to therapy. Plasma sialyltransferase and CEA level correlated well in 10 colon, 4 breast and 1 lung cancer patients in response to therapy. There was a negative correlation in one colon cancer, 3 breast cancer and 2 lung cancer patients. Plasma sialyltransferase was a better marker for breast and lung cancer. CEA was a good marker for colon cancer.
D001943:Breast Neoplasms / Q000188:drug therapy; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D003110:Colonic Neoplasms / Q000188:drug therapy; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology / Q000276:immunology; D012799:Sialyltransferases / Q000097:blood*; D014166:Transferases / Q000097:blood*; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase
D002272:Carcinoembryonic Antigen; D014166:Transferases; D012799:Sialyltransferases; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase