A mathematical model of exoprotein production in bacteria.
We present a simple mathematical model for the synthesis of extracellular proteins by a class of bacteria which secrete significant quantities of this exoprotein in late-exponential and stationary phases. This model is the simplest generalization of Michaelis-Menten kinetics (the Monod model) and agrees well with laboratory experiments in batch culture. The model may serve as a simple prototype for the analysis of certain virulent bacterial infections in vivo, particularly that of Pseudomonas aeruginosa in burn wounds.
D001419:Bacteria / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000096:biosynthesis*; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological
D001426:Bacterial Proteins