Urinary glycoproteins in acute leukemias: a 41 000 dalton glycoprotein follows the kinetic of cytoreduction.
Glycoproteins of leukemic cells and 24-hour urinary proteins were subjected to SDS polyacrylamide gel electrophoresis followed by affinity labelling I125 with Concanavalin A, indicating glycoproteins with mannose and/or glucose carbohydrate residues. Among the cellular glycoproteins a 41 000 dalton glycoprotein appeared under induction therapy in close correlation to the reduction of leukemic cells in ALL as well as in AML.
D002470:Cell Survival; D006023:Glycoproteins / Q000652:urine*; D006801:Humans; D007700:Kinetics; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000652:urine*; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000652:urine*; D008565:Membrane Proteins / Q000652:urine*; D008970:Molecular Weight
D006023:Glycoproteins; D008565:Membrane Proteins