Amino acid composition of salivary protein secreted by the parotid glands of rats in response to parasympathomimetic and sympathomimetic drugs.
Although the total protein concentration in the saliva varied markedly, depending on the nature of the stimulus, the proportions of the amino-acid residues were independent on the nature of the stimuli, where they were cholinergic, adrenergic or dopaminergic. However, the difference in protein composition of saliva previously shown in chronically isoprenaline-treated rats electrophoretically could be determined by amino-acid analysis.
D000596:Amino Acids / Q000032:analysis*; D000818:Animals; D004298:Dopamine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D010277:Parasympathomimetics / Q000494:pharmacology*; D010306:Parotid Gland / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000032:analysis / Q000187:drug effects; D012471:Salivary Proteins and Peptides / Q000032:analysis*; D013268:Stimulation, Chemical; D013566:Sympathomimetics / Q000494:pharmacology*
D000596:Amino Acids; D010277:Parasympathomimetics; D012471:Salivary Proteins and Peptides; D013566:Sympathomimetics; D007545:Isoproterenol; D004298:Dopamine