[Changes in the variant of acute leukemia].
The authors describe a female patient with acute lymphoblastic leukemia. After the first chemotherapy cycle according to the VAMP program the patient developed a complete remission. Further on, repeated extramedullary relapses (neuroleukemia, involvement of the mammary gland tissue and lymph nodes of the mesentery) were observed over 7 years, the data of blood and bone marrow analyses being within normal. At the end of the disease the patient developed a relapse with changes in the blood and bone marrow, however the blast cells were sudan and peroxidase-positive i.e. could be classified as myeloblasts.
D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000209:etiology*; D008214:Lymphocytes / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology*
K voprosu ob izmenenii varianta ostrogo leĭkoza.