[Chronic lymphoid leukemia followed by acute monocytic leukemia].
A 62 year old patient with CLL treated by alkylating drugs for more than three years, underwent acute leukaemia (AL). The clinical particularities of the onset and course of this AL, the cytological, cytoenzymological and ultrastructural characteristics of the blasts are discussed in order to find a relation between the two hemopathies. A possible drug-induced etiology of this AL is proposed.
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D001773:Blood Cells / Q000648:ultrastructure; D001853:Bone Marrow / Q000648:ultrastructure; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000188:drug therapy / Q000648:ultrastructure; D007948:Leukemia, Monocytic, Acute / Q000209:etiology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents
Leucémie lymphoïde chronique suivie d'une leucémie aiguë monocytaire. Etude clinique et cytologique.