Typing of HLA antigens in a child population with nephrosis syndrome.
Using the microlymphocytotoxicity test of Terasaki, HLA--A, B, Cw antigen typing was done for 37 antigens in 28 children with steroid-sensitive nephrosis and five children with steroid-resistant nephrosis. Evaluation was made by the chi 2 test as corrected by the method of Yeates. In steroid-sensitive nephrosis the frequency of HLA--B 8 antigen was 33.3% and in the resistant cases 40% as against 18.5% in the controls. The difference, however, was not significant, the B 12 and B 13 antigens were more frequent in both steroid-sensitive and resistant nephrosis, though not significantly.
D002648:Child; D006680:HLA Antigens / Q000276:immunology / Q000302:isolation & purification*; D015235:HLA-B Antigens; D059908:HLA-B13 Antigen; D015236:HLA-C Antigens; D006801:Humans; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000276:immunology*; D010641:Phenotype
D006680:HLA Antigens; D015235:HLA-B Antigens; C035015:HLA-B12 antigen; D059908:HLA-B13 Antigen; D015236:HLA-C Antigens