Craniofacial development: the possible mechanisms for some malformations.
Normal craniofacial development is reviewed and some mechanisms in the fusion of mammalian facial 'processes' are discussed. The manipulation of environmental factors and effects of teratogens are related to genetic susceptibility of animal models, and extrapolated to craniofacial malformations in man.
D000014:Abnormalities, Drug-Induced / Q000196:embryology; D000818:Animals; D002642:Chick Embryo; D004195:Disease Models, Animal; D005314:Embryonic and Fetal Development; D005145:Face / Q000002:abnormalities / Q000196:embryology*; D005823:Genetics; D006801:Humans; D008322:Mammals / Q000196:embryology; D009432:Neural Crest / Q000502:physiology; D051381:Rats; D012886:Skull / Q000002:abnormalities / Q000196:embryology*; D013723:Teratogens
D013723:Teratogens