Salivary gland dysfunction following radioactive iodine therapy.
Radioactive iodine is used extensively for the treatment of thyrotoxicosis and thyroid carcinoma. Iodine is actively taken up by the salivary glands and, following its use, salivary dysfunction may result as a consequence of radiation damage. The literature is reviewed and a case is reported in which a patient presented with a significant increase in caries rate attributed to salivary dysfunction following radioactive iodine therapy for a thyroid carcinoma.
D000328:Adult; D003731:Dental Caries / Q000209:etiology; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D012469:Salivary Glands / Q000503:physiopathology / Q000528:radiation effects*; D013964:Thyroid Neoplasms / Q000188:drug therapy; D014987:Xerostomia / Q000209:etiology* / Q000503:physiopathology
D007457:Iodine Radioisotopes