HLA-DR in meningopolyneuritis of Garin-Bujadoux-Bannwarth: contrast to Lyme disease?
Sixteen patients with meningopolyneuritis of Garin-Bujadoux-Bannwarth (MPN-GBB) were examined for HLA-DR antigens. In contrast to data in Lyme disease (LD), which is caused by an identical or closely related spirochete, no significant association was found between the neurological disease and HLA-DR. The reported association between neurological disease and HLA-DR2 in LD may be due to the inclusion of cases with neurological disease and arthritis, since chronic arthritis in LD seems to be well correlated with HLA-DR2.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001168:Arthritis / Q000276:immunology; D005260:Female; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D006801:Humans; D008193:Lyme Disease / Q000276:immunology*; D008297:Male; D008581:Meningitis / Q000150:complications* / Q000276:immunology; D008875:Middle Aged; D011115:Polyneuropathies / Q000150:complications* / Q000276:immunology
D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II