Effect of inhibition of net calcium uptake on net fluoride uptake in developing rat molars.
Two methods were used to reduce net calcium uptake by the secretory stage enamel of developing rat molar explants. Neither method had a significant effect on fluoride uptake by the explants. These findings indicate that the mechanisms for uptake in the developing enamel are independent for calcium and fluoride.
D000818:Animals; D002118:Calcium / Q000037:antagonists & inhibitors* / Q000378:metabolism; D003035:Cobalt / Q000494:pharmacology; D046508:Culture Techniques; D003743:Dental Enamel / Q000187:drug effects / Q000378:metabolism; D004658:Enamel Organ / Q000187:drug effects / Q000378:metabolism*; D005459:Fluorides / Q000378:metabolism*; D008963:Molar; D051381:Rats; D014074:Tooth Calcification / Q000187:drug effects; D014083:Tooth Germ / Q000378:metabolism*
D003035:Cobalt; D005459:Fluorides; D002118:Calcium