Central nervous system involvement as a presenting feature of acute monocytic leukemia: preceding leukemia by 12 months.
This report describes a patient who presented with a diffuse malignant central nervous system (CNS) process composed of cells with monocytic differentiation one year before the development of acute monocytic leukemia. A similar presentation has been documented for acute lymphocytic leukemia, but to the best of our knowledge, this is the first report to detail a diffuse CNS malignancy as the presenting symptom for acute monocytic leukemia.
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D002466:Cell Nucleolus / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid / Q000473:pathology*; D003593:Cytoplasm / Q000473:pathology; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D008297:Male; D009423:Nervous System Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology*; D013997:Time Factors