Phospholipids associated with human parotid gland sialoliths.
Ca-acidic phospholipid-phosphate complexes (CPLX) were isolated from 6 whole and 2 pooled human parotid sialoliths containing the mineral phases hydroxyapatite, whitlockite and octacalcium phosphate (ash 78 +/- 16 per cent, n = 7). Total lipids accounted for 25 per cent of the demineralized dry weight of these sialoliths. CPLX was 39 +/- 18 per cent of the lipid phosphorous pool, while diphosphatidyl glycerol, phosphatidyl ethanolamine and phosphatidyl choline were the principal non-complexed phospholipids. The high cholesterol:phospholipid molar ratio (1.0 +/- 0.3) observed in the sialolith lipids suggests a plasma membrane origin for these lipids.
D006801:Humans; D008055:Lipids / Q000032:analysis; D008903:Minerals / Q000032:analysis; D010306:Parotid Gland / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis*; D012465:Salivary Duct Calculi / Q000378:metabolism*
D008055:Lipids; D008903:Minerals; D010743:Phospholipids