Comparison of 20-oxosteroids and cortisol in urine as parameters of adrenocortical function.
The coefficient of correlation between values for urinary 20-oxosteroids and urinary cortisol was 0.75 in 106 24-hours urines. Urinary cortisol was usually the more specific and sensitive parameter for the evaluation of adrenocortical function. With an analysis time of 4-5 hours for 100 samples, the method for cortisol was also faster and cheaper. Furthermore, the intra- and interassay variances of 2.7 and 8.2%, respectively, indicate high precision.
D015089:20-Hydroxysteroid Dehydrogenases; D000302:Adrenal Cortex / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D007664:Ketosteroids / Q000652:urine; D011863:Radioimmunoassay / Q000379:methods; D012016:Reference Values
D007664:Ketosteroids; D015089:20-Hydroxysteroid Dehydrogenases; D006854:Hydrocortisone