Cell kinetics of hamster ventral tongue epithelium in iron deficiency.
The cell-kinetic parameters of labelling index and duration of the S phase of the cell cycle (Ts) were investigated in the ventral tongue epithelium of hamsters with experimentally-induced iron deficiency. The labelling indices in animals with iron-deficiency anaemia and iron deficiency without anaemia did not differ from normal, but the Ts values were significantly shorter indicating an increased cell-production rate. The epithelial cell-kinetic parameters of iron-depleted animals did not differ from normal, but the labelling index was greater than in animals with the more severe stages of iron deficiency.
D000747:Anemia, Hypochromic / Q000473:pathology; D000818:Animals; D002453:Cell Cycle; D006224:Cricetinae; D004848:Epithelium / Q000473:pathology; D007399:Interphase; D000090463:Iron Deficiencies; D008297:Male; D008647:Mesocricetus; D014059:Tongue / Q000473:pathology*