Phenytoin-induced agranulocytosis after treatment for a gunshot wound to the face.
A case of phenytoin-induced agranulocytosis is presented. This syndrome is characterized by a decrease in the blood neutrophil count to very low levels. Patients are generally asymptomatic, but they may become febrile and develop an infection, which is frequently fatal. Practitioners treating trauma patients or other patients in whom phenytoin treatment is initiated should be aware of the potential development of agranulocytosis.
D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008337:Mandibular Fractures / Q000150:complications; D019838:Neck Injuries; D010672:Phenytoin / Q000009:adverse effects*; D012640:Seizures / Q000517:prevention & control; D014948:Wounds, Gunshot / Q000150:complications
D010672:Phenytoin