Acquired partial deletions of the long arm of chromosome 5 in hematologic disorders.
We have analyzed the data on 105 patients reported with a deletion of part of the long arm of chromosome 5 in the presence of hematologic disease. The major conditions associated with this abnormality are refractory anemia, polycythemia vera, and acute myelogenous leukemia, as well as the occasional occurrence of several other problems.
D000741:Anemia, Aplastic / Q000235:genetics*; D002872:Chromosome Deletion; D002905:Chromosomes, Human, 4-5; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008223:Lymphoma / Q000235:genetics; D009101:Multiple Myeloma / Q000235:genetics; D011087:Polycythemia Vera / Q000235:genetics*; D055728:Primary Myelofibrosis / Q000235:genetics