Trichosporon capitatum: thrush-like oral infection, local invasion, fungaemia and metastatic abscess formation in a leukaemic patient.
A thrush-like oral infection with subsequent alveolar abscess formation and a positive blood culture due to Trichosporon capitatum developed in a patient with acute myelogenous leukaemia. Later T. capitatum was identified by indirect immunofluorescence in multiple splenic abscesses. The infection was controlled by immediate aggressive treatment with amphotericin B, flucytosine and rifampicin and by splenectomy. This case of systemic T. capitatum infection resembles somewhat the invasive mycosis due to candida.
D000038:Abscess / Q000382:microbiology; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001769:Blood / Q000382:microbiology; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D003904:Mitosporic Fungi; D009181:Mycoses / Q000150:complications* / Q000628:therapy; D012293:Rifampin / Q000627:therapeutic use; D013158:Splenic Diseases / Q000382:microbiology
D000666:Amphotericin B; D005437:Flucytosine; D012293:Rifampin