[Prostaglandin E2--an improvement in the therapy of bladder emptying disorders?].
21 patients suffering from bladder motor disturbances were investigated by simultaneous pressure-flow studies before and after intravesical application of PGE2. The detrusor response as well as the influence on the bladder outlet resistance were registered. A remarkable improvement of the detrusor function could only be obtained in cases with intact sacral reflex-arcs with isolated transitory myogenic disturbances. Neuromyogenic bladder disturbances could not be influenced permanently by PGE2 instillations.
D000293:Adolescent; D000328:Adult; D000368:Aged; D015232:Dinoprostone; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects; D011458:Prostaglandins E / Q000494:pharmacology / Q000627:therapeutic use*; D001745:Urinary Bladder Diseases / Q000188:drug therapy*
D011458:Prostaglandins E; D015232:Dinoprostone
Prostaglandin E2--Eine Bereicherung in der Therapie der Blasenentleerungsstörungen?