Effect of sodium meclofenamate on ultraviolet radiation induced carcinogenesis.
Sodium meclofenamate (Meclomen), an antiprostaglandin antileukotriene agent, was found in previous studies to protect primates against x-ray induced brain edema, esophagitis and cystitis. In the present study, it appeared to protect hairless mice against the carcinogenic effect of ultraviolet B-radiation.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000517:prevention & control*; D008297:Male; D008469:Meclofenamic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D051379:Mice; D008812:Mice, Hairless; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000517:prevention & control*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D062367:ortho-Aminobenzoates / Q000627:therapeutic use*
D062367:ortho-Aminobenzoates; D008469:Meclofenamic Acid