Busulfan-induced hemorrhagic cystitis.
We report a case of severe hemorrhagic cystitis induced by prolonged busulfan therapy. The clinical course and pathological results were similar to irradiation and cyclophosphamide cystitis. Only 1 such case has been described previously. Although hemorrhagic cystitis induced by busulfan is a rare complication it should be considered in the differential diagnosis and busulfan should be discontinued immediately.
D000328:Adult; D002066:Busulfan / Q000008:administration & dosage / Q000009:adverse effects*; D003556:Cystitis / Q000139:chemically induced*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy; D013997:Time Factors; D001745:Urinary Bladder Diseases / Q000139:chemically induced
D002066:Busulfan