Chronic myelogenous leukemia in the dog.
Chronic myelogenous leukemia was diagnosed in 7 dogs. In each case, marked neutrophilia in the absence of infection was observed in association with nonspecific illness. Diagnosis was based on morphologic cytology of blood smears, bone marrow aspirates, and in 1 case, a lymph node biopsy specimen. In 5 cases, treatment with hydroxyurea was successful in lowering circulating WBC counts, but was of questionable value in the prevention of leukemic blast crisis.
D000818:Animals; D001707:Biopsy, Needle; D001772:Blood Cell Count / Q000662:veterinary; D001853:Bone Marrow / Q000473:pathology; D003581:Cytodiagnosis / Q000662:veterinary; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D004359:Drug Therapy, Combination; D005260:Female; D006918:Hydroxyurea / Q000627:therapeutic use; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D010110:Oxymetholone / Q000627:therapeutic use
D010110:Oxymetholone; D006918:Hydroxyurea