Evaluation of etidocaine hydrochloride for local anesthesia and postoperative pain control in oral surgery.
Etidocaine hydrochloride, an amide-type local anesthetic with prolonged duration of action, was evaluated and compared with a standard local anesthetic, lidocaine, to determine its efficacy as a local anesthetic and its effect on postoperative pain following removal of impacted third molars. The findings indicate that 1.5% etidocaine hydrochloride with 1:200,000 epinephrine, in comparison with 2% lidocaine hydrochloride with 1:100,000 epinephrine, suppresses the magnitude of postoperative pain, and results in anesthesia comparable with that obtained by lidocaine, but results in greater blood loss during surgery.
D000083:Acetanilides / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D005041:Etidocaine / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008340:Mandibular Nerve; D009407:Nerve Block; D010149:Postoperative Pain / Q000517:prevention & control*; D013997:Time Factors; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery
D000083:Acetanilides; D008012:Lidocaine; D005041:Etidocaine