Case report of tricyclic-induced delirium at a therapeutic drug concentration.
A patient receiving a standard dose of imipramine developed a drug-induced delirium. Her plasma antidepressant level was in the low therapeutic range. Thus, tricyclic-induced delirium may in some cases be an idiosyncratic phenomenon unrelated to plasma drug concentration.
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects; D003693:Delirium / Q000139:chemically induced*; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy; D005260:Female; D006801:Humans; D007099:Imipramine / Q000009:adverse effects* / Q000097:blood; D011605:Psychoses, Substance-Induced / Q000209:etiology
D000929:Antidepressive Agents, Tricyclic; D007099:Imipramine