Pharmacokinetics of pindolol in Kenyan Africans.
The pharmacokinetics of pindolol was studied in 8 normal Africans following administration of a single oral 10 mg dose. The mean peak concentration was 30.2 +/- 5.0 ng X ml-1, the mean half-life (t1/2) of the elimination phase was 3.4 +/- 1.1 h, and the total body clearance was 628 +/- 13 ml X min-1. The apparent volume of distribution was 3.0 +/- 1.31 X kg-1. The values are the same as those reported in Europeans.
D000328:Adult; D044383:Black People; D006801:Humans; D007630:Kenya; D007700:Kinetics; D010869:Pindolol / Q000378:metabolism*
D010869:Pindolol