title: Production of penicillinases by certain penicillin-resistant bacteria. (C) factors affecting the activities of penicillinases produced by Staphylococcus aureus, S9.
abstract: The activities of penicillinases produced by Staphylococcus aureus, S9 were found to be affected by pH, temperature, substrate concentration and type of penicillin derivative used as a substrate. The optimal activities of penicillinases produced by S. aureus, S9 were obtained at pH 6, at 37 degrees C, 0.5-10 mu/ml penicillin G concentration, and by increasing the enzyme concentration.
mesh_terms: D006863:Hydrogen-Ion Concentration; D010400:Penicillin G / Q000378:metabolism; D010405:Penicillinase / Q000096:biosynthesis*; D013211:Staphylococcus aureus / Q000201:enzymology*; D013696:Temperature
chemical_list: D010405:Penicillinase; D010400:Penicillin G