Familial spastic paraplegia with Kallmann's syndrome.
A sibship is reported in which two males have spastic paraparesis and Kallmann's syndrome (hypogonadotrophic hypogonadism and anosmia). One of the brothers also is color blind. The association of familial spastic paraplegia and Kallmann's syndrome has not been described previously.
D000328:Adult; D002675:Child, Preschool; D003117:Color Vision Defects / Q000235:genetics; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D007006:Hypogonadism / Q000235:genetics*; D008297:Male; D009128:Muscle Spasticity / Q000235:genetics; D000857:Olfaction Disorders / Q000235:genetics*; D010264:Paraplegia / Q000235:genetics*; D010375:Pedigree; D012021:Reflex, Abnormal / Q000235:genetics; D013577:Syndrome
D006065:Gonadotropins, Pituitary