title: Phospholipids and cholesterol in brush border and basolateral membranes from rat intestinal mucosa.
abstract: Total phospholipids and free cholesterol reach higher levels in basolateral membranes than in brush border membranes, these membranes being purified from rat intestinal mucosa. Cholesterol/phospholipid and cholesterol/phospholipid choline molar ratios are lower in basolateral membranes. Lysophosphatidylcholine, sphingomyelin and phosphatidylinositol are approximately twice as high in brush border membranes (respectively, 8.7, 24.1 and 22.3% total lipid phosphorus) when compared to basolateral membranes (respectively, 3.6, 12.5 and 11.5% total lipid phosphorus). Conversely, basolateral membranes are richer than brush border membranes in phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and diphosphatidylglycerol (basolateral membranes: 36.9, 8.1, 24.8, 1.7% total lipid phosphorus; brush border membranes: 26.7, 4.4, 11.9, 0.5% total lipid phosphorus.
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000378:metabolism*; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism*; D008297:Male; D008566:Membranes / Q000378:metabolism; D008871:Microvilli / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010743:Phospholipids; D002784:Cholesterol