TruCut needle biopsy in sarcoidosis. Relationship between histology of the biopsy specimens and radiographic features and pulmonary function.
Ninety-nine TruCut needle biopsies were performed on 92 patients with sarcoidosis. Non-caseating granulomas were found in 77 of 92 patients (84%) and in 78 of 99 biopsies (79%). Granulomas were found in 67% of patients showing only slight radiographic opacity (ILO classification grades 0/0-1/1) and in 90% of patients with higher radiographic grades (ILO 1/2-3/3). There was also a positive relationship between the size of the biopsy specimen and the presence of granulomas. Granulomas were found in 68% of small biopsy specimens and in 90% of moderate or large specimens.
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012129:Respiratory Function Tests; D012507:Sarcoidosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology