[Biology of adult T-cell leukemia virus].
Biologic activities of adult T-cell leukemia (ATL) virus (ATLV) were studied. The results are summarized as follows: 1) Cell-free ATLV are able to infect to and induce ATLA in normal human lymphocytes. 2) ATLV is infectable not only to T cells but also to B cells. 3) A glycoprotein of an apparent molecular mass of 46,000, gp46, is a novel component of the ATLA antigen complex and may represent a major viral envelope glycoprotein. These data add important information to the study of etiological role of ATLV in the leukemia.
D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002472:Cell Transformation, Viral; D006023:Glycoproteins / Q000302:isolation & purification; D006801:Humans; D007938:Leukemia / Q000276:immunology / Q000382:microbiology*; D008970:Molecular Weight; D012190:Retroviridae / Q000254:growth & development / Q000276:immunology / Q000502:physiology*; D013601:T-Lymphocytes
D000956:Antigens, Viral; D006023:Glycoproteins