A new familial "fragile site" on chromosome 16 (q23-24). Cytogenetic and clinical considerations.
A new familial fragile site at 16q23-24 is documented, and the clinical and cytogenetic data on three families and some individual patients are reported. The importance of differentiating this fragile site from that recognized previously at 16q22 is pointed out.
D000026:Abortion, Habitual / Q000235:genetics; D000328:Adult; D002648:Child; D002871:Chromosome Banding; D043283:Chromosome Fragile Sites; D002873:Chromosome Fragility; D002902:Chromosomes, Human, 16-18; D003410:Cri-du-Chat Syndrome / Q000235:genetics; D005097:Exostoses, Multiple Hereditary / Q000235:genetics; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D011247:Pregnancy