[Assessment of fetal maturity by measurement of the phospholipids in the amniotic fluid. Comparison of the results with the lecithin/sphingomyelin ratio].
The authors explored the possibility of assessing fetal lung maturity by measuring the phospholipids in the amniotic fluid by the enzymatic technique of Takayama et al. [8]. The study was conducted on 41 pregnancies. The results obtained were evaluated comparatively with the lecithin/sphingomyelin ratio (L/S). The authors found that the L/S ratio can be used to determine fetal lung maturity in 93% of cases with 2/14 false maturities and 1/27 false immaturities. The assay of the phospholipids containing choline by the method of Takayama et al. [8] gives a much less precise assessment of fetal lung maturity: only 68% of the results were concordant; 5/14 false maturities and 8/27 false immaturities. These differences can be explained by the fact that the method of Takayama et al. [8] takes into account substances which are not related to process of fetal lung maturation.
D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D008168:Lung / Q000196:embryology*; D010713:Phosphatidylcholines / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D013109:Sphingomyelins / Q000032:analysis*
D010713:Phosphatidylcholines; D010743:Phospholipids; D013109:Sphingomyelins
Appréciation de la maturité foetale par la mesure des phospholipides du liquide amniotique. Comparaison des résultats avec le rapport lécithine/sphingomyéline.