Neonatal intracranial haemorrhage: the cause of the ultrasound appearances.
We report experimental studies showing the relationship of the reflectivity of blood clot to both the red cell mass and the fibrin mesh. The highest amplitude echoes are returned by the fibrin mesh. These studies are compared with clinical examples of the different types of neonatal intracranial haemorrhage, as demonstrated by ultrasound. We conclude that the typical high-amplitude echoes characteristic of intracerebral haemorrhage are primarily due to the amount of fibrin mesh present, and not to the intact red cell mass, as has been previously suggested.
D001777:Blood Coagulation; D002543:Cerebral Hemorrhage / Q000097:blood / Q000175:diagnosis*; D002552:Cerebral Ventricles; D002908:Chronic Disease; D004911:Erythrocyte Volume; D005337:Fibrin; D006408:Hematoma, Subdural / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis; D014463:Ultrasonography
D005337:Fibrin