[Anti-SS-B antibody : marker of Gougerot-Sjögren's connective tissue disease independent of the dry syndrome].
We studied the predictive value of anti-SS-B antibody on 48 patients having this antibody and no other antinuclear antibody. 25 patients had a typical Sjögren syndrome and the rest had no sicca syndrome but generally an unclassified disease. Between these two groups of patients we observed an identity of clinical and biological manifestations except for the sicca syndrome. We conclude that anti-SS-B antibody is not a marker for Sjögren syndrome, but is correlated with the presence of an autoimmune disorder inconstantly associated with the sicca syndrome. This auto-immune disorder has the clinical and biological features of systemic Sjögren syndrome but the sicca syndrome.
D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis*; D000941:Antigens / Q000276:immunology*; D001324:Autoantigens; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012261:Ribonucleoproteins; D012859:Sjogren's Syndrome / Q000175:diagnosis / Q000276:immunology*; D013997:Time Factors; D000097585:SS-B Antigen
D000974:Antibodies, Antinuclear; D000941:Antigens; D001324:Autoantigens; D012261:Ribonucleoproteins; D000097585:SS-B Antigen
L'anticorps anti-SS-B : marqueur de la "connectivite de Gougerot-Sjören" indépendamment du syndrome sec.