title: Chemical structures of angiotensins formed by incubating plasma with the kidney and the corpuscles of Stannius in the chum salmon, Oncorhynchus keta.
abstract: The chemical structures of salmon angiotensins produced by incubating tissue extract of the kidney or the corpuscles of Stannius (CS) with homologous plasma are proposed. Two angiotensins, [Asp1, Val5, Asn9] and [Asn1, Val5, Asn9] angiotensin I, were proposed from both kidney and CS incubations by amino acid analysis and the fluorescent peptide-mapping techniques. CS angiotensins were not organ specific, because these two angiotensins were produced by both kidney and CS incubations in a ratio of 1:2 under the same conditions. Whether [Asp1, Val5, Asn9] angiotensin I is a naturally occurring form remains to be clarified; however, [Asn1, Val5, Asn9] angiotensin I may be the major form of angiotensin formed from plasma by salmon kidney and CS.
mesh_terms: D000595:Amino Acid Sequence; D000809:Angiotensins / Q000008:administration & dosage / Q000302:isolation & purification; D000818:Animals; D001794:Blood Pressure; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D005260:Female; D007668:Kidney / Q000032:analysis / Q000378:metabolism*; D009928:Organ Specificity; D010455:Peptides / Q000032:analysis; D010949:Plasma / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012474:Salmon / Q000378:metabolism*
chemical_list: D000809:Angiotensins; D010455:Peptides