Bile lipid output and composition in patients fitted with external biliary drainage: activity of cicloxilic acid.
In 7 patients with external biliary drainage for total occlusion of the extrahepatic bile ducts the bile output was measured in 3-day periods, with and without cicloxilic acid treatment (240 mg daily, per os). The output increased markedly during treatment in all cases. In the 3 patients in whom the bile lipid composition was analyzed also, the bile salt and phospholipid concentrations increased while the cholesterol concentration was unchanged--with an consequent lowering of the biliary cholesterol saturation index--during treatment with cicloxilic acid.
D000368:Aged; D001646:Bile / Q000032:analysis*; D002756:Cholagogues and Choleretics / Q000627:therapeutic use*; D001651:Cholestasis, Extrahepatic / Q000628:therapy*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D004322:Drainage; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008297:Male
D002756:Cholagogues and Choleretics; D003509:Cyclohexanecarboxylic Acids; D008055:Lipids; C018873:cicloxilic acid