[Polymorphism of NOR bands in a normal French population].
The segregation of NORs-Ag positive and negative acrocentric chromosomes was studied with a combined staining technique (Ag-I/RHG), in a normal French population (Saint-Etienne, Loire, France). The observed frequencies of homozygous and heterozygous NOR-Ag individuals, either for each acrocentric pair or for all the pairs of acrocentric chromosomes are not statistically different from the ones expected according to Hardy-Weinberg's law. The genotypic frequencies of homozygous subjects (+/+) for each acrocentric pair are the following: 13: 0,900; 14: 0,895; 15: 0,880; 21: 0,900 and 22: 0,870. The average modal number of NOR-Ag positives for the sample is 8,58 +/- 0,81. The comparison between these results and other data from European Caucasian populations, was possible by using the same criteria of classification. The discriminative value of NOR banding polymorphisms is discussed.
D002478:Cells, Cultured; D002871:Chromosome Banding; D005260:Female; D005602:France; D005787:Gene Frequency; D005828:Genetics, Population; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D011110:Polymorphism, Genetic
Polymorphisme des bandes NOR dans une population française normale.