Regional assignment of human amylase (AMY) to p22----p21 of chromosome 1.
A human genomic DNA segment (lambda hal) which hybridizes with rat pancreatic amylase cDNA was used to regionally assign amylase genes in human-mouse somatic cell hybrids. The assignment of amylase genes to chromosome 1 was confirmed and regionally mapped to the short arm region p22.1----p21 using a cell hybrid retaining a translocation involving chromosome 1 [46,XX,t(1;2)(p21;q37)]. Restriction length polymorphisms at the amylase loci are reported for gene linkage studies.
D000818:Animals; D002900:Chromosomes, Human, 1-3; D003001:Cloning, Molecular; D004247:DNA; D005796:Genes; D006367:HeLa Cells; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D051379:Mice; D009693:Nucleic Acid Hybridization; D010179:Pancreas / Q000201:enzymology; D014176:Protein Biosynthesis; D000516:alpha-Amylases / Q000235:genetics*
D004247:DNA; D000516:alpha-Amylases