Hemopoietic responses of LPS-unresponsive C3H/HeJ mice to salmonella infection.
Effects of Salmonella enteritidis infection on hemopoietic stem cells were examined in LPS-unresponsive C3H/HeJ mice. The salmonella infection increased pluripotent stem cells (CFUs) and granulocyte-macrophage progenitor cells (CFUc) in the spleen and decreased these hemopoietic stem cells in the bone marrow. These responses seemed to be specific to salmonella infection and not due to biological activities of LPS.
D000818:Animals; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000187:drug effects*; D006412:Hematopoietic Stem Cells / Q000187:drug effects; D008070:Lipopolysaccharides / Q000494:pharmacology*; D051379:Mice; D008809:Mice, Inbred C3H; D012480:Salmonella Infections / Q000097:blood* / Q000382:microbiology; D013154:Spleen / Q000187:drug effects; D013997:Time Factors
D008070:Lipopolysaccharides