Susceptibility of lipids to mercurials.
Affinity of mercury compounds to various phospholipids and fatty acids were examined. Inorganic mercury showed a higher affinity to lipids containing unsaturated fatty acids than to those composed of saturated fatty acids. This suggests that inorganic mercury may easily act on the double bonds of fatty acid residues in phospholipids which are major components of the biomembrane. On the other hand, methylmercury was almost inert to these lipids regardless of the presence or absence of unsaturated bonds.
D055598:Chemical Phenomena; D002621:Chemistry; D005227:Fatty Acids / Q000378:metabolism; D008081:Liposomes / Q000378:metabolism; D008563:Membrane Lipids / Q000378:metabolism*; D008628:Mercury / Q000378:metabolism*; D008631:Mercury Radioisotopes; D008767:Methylmercury Compounds / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism
D005227:Fatty Acids; D008081:Liposomes; D008563:Membrane Lipids; D008631:Mercury Radioisotopes; D008767:Methylmercury Compounds; D010713:Phosphatidylcholines; D010743:Phospholipids; D008628:Mercury; C004925:methylmercuric chloride