[Comparative investigation of the dynamic conformational properties of human myeloma immunoglobulin G of different subclasses using impulse NMR].
The evidence of the intramolecular flexibility of human myeloma immunoglobulin G belonging to the second, third and fourth subclasses has been obtained using the impulse NMR method. It has been found that the degree of intramolecular flexibility for the myeloma immunoglobulin G belonging to the first subclass decreases significantly by cooling from 37 to 10 degrees.
D006801:Humans; D007074:Immunoglobulin G / Q000302:isolation & purification*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009194:Myeloma Proteins; D011487:Protein Conformation; D013329:Structure-Activity Relationship
D007074:Immunoglobulin G; D009194:Myeloma Proteins
Sravnitel'noe issledovanie dinamicheskikh konformationnykh svoĭstv mielomnykh immunoglobulinov G cheloveka raznykh podklassov impul'snym metodom IaMR.