title: External application of antibiotic to improve survival of adult laboratory frogs (Rana pipiens).
abstract: Survival data for over 500 adult frogs (393 Rana pipiens, 35 Rana clamitans , and 97 Rana temporaria) obtained from commercial suppliers were accumulated. Frogs which developed signs of red-leg disease while being kept in 0.15% saline were cured by addition of appropriate antibiotics to the saline. The appropriate antibiotic was determined by sensitivity testing of bacteria isolated from the sick frogs. When many frogs in a shipment were sick, prophylactic treatment of the entire shipment improved the overall survival in the shipment.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000662:veterinary*; D007868:Leg Dermatoses / Q000188:drug therapy / Q000662:veterinary; D011894:Rana pipiens / Q000382:microbiology*; D011896:Rana temporaria / Q000382:microbiology; D012874:Skin Diseases, Infectious / Q000188:drug therapy / Q000662:veterinary*; D012965:Sodium Chloride / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012965:Sodium Chloride