title: Adult idiopathic pulmonary haemosiderosis: a comparison of lung function changes and the distribution of pulmonary disease in patients with and without coeliac disease.
abstract: Seven patients with idiopathic pulmonary haemosiderosis were investigated with chest radiographs, pulmonary function tests, computed axial tomograms, and isotope ventilation and perfusion scans. Three of the patients had coeliac disease (CD) and a fourth an abnormal small bowel mucosa under the dissecting microscope which was normal histologically. Five patients showed airflow limitation with a low transfer coefficient. Three of these had air trapping, two of whom had hyperinflation of the lungs, and the third a total lung capacity at the upper limit of normal. Two patients showed a central distribution of radiographic opacities, and the other five had changes throughout the lung fields. The presence or absence of CD showed no relationship to these findings.
mesh_terms: D000328:Adult; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006486:Hemosiderosis / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged