New findings in posterior amorphous corneal dystrophy.
Eight members of a family spanning five generations were found to have posterior amorphous corneal dystrophy. This rare abnormality was noted in both its centroperipheral and peripheral forms. The following five heretofore unrecognized features were noted: (1) hyperopia, (2) flattened corneal topography, (3) anterior iris surface and stromal abnormalities, (4) fine iris processes extending to Schwalbe's line for 360 degrees, and (5) extension of the opacity to the limbus. The presence of this dystrophy in a 6-month-old family member further suggests the possibility that it is a congenital abnormality.
D000328:Adult; D000368:Aged; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007498:Iris / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D014792:Visual Acuity