Morphological evidence for tracer uptake at the active zones of stimulated frog neuromuscular junction.
Lanthanum or ferritin added to the fixative were found in small and non-coated vesicles located at active zones in nerve-muscle preparations stimulated by potassium during cold aldehyde fixation. The presence of labeled vesicles at active zones supports the hypothesis that a double process of exo-endocytosis might occur under moderate stimulation conditions.
D000818:Animals; D001665:Binding Sites; D005293:Ferritins / Q000378:metabolism; D007811:Lanthanum / Q000378:metabolism; D008854:Microscopy, Electron; D009469:Neuromuscular Junction / Q000378:metabolism / Q000648:ultrastructure*; D011188:Potassium / Q000378:metabolism; D011893:Rana esculenta; D013572:Synaptic Vesicles / Q000378:metabolism / Q000648:ultrastructure
D007811:Lanthanum; D005293:Ferritins; D011188:Potassium