Enkephalins--enhancement of active T-cell rosettes from normal volunteers.
Both methionine enkephalin and leucine enkephalin were found to increase significantly the active T-cell rosettes of normal volunteers. Neither enkephalin altered total T-cell rosettes. It is proposed that the endogenous enkephalins (methionine as well as leucine) have a role in cell-mediated immunity and T-cell function.
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000328:Adult; D004743:Enkephalin, Leucine / Q000494:pharmacology* / Q000502:physiology; D004744:Enkephalin, Methionine / Q000494:pharmacology* / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D000276:Adjuvants, Immunologic; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine