[T-cell kinetics and course of humoral immune response following subcutaneous immunization with tetanus toxoid fluid vaccine].
Revaccinations with tetanus toxoid fluid vaccine were performed including different groups of volunteers (aged, diabetics, rheumatics). The kinetics of T-cells were demonstrated by rosette technique in a period of 63 days after revaccination. The content of tetanus antitoxin was estimated by the mouse standard neutralization test. T-cell kinetics were different in the investigated groups, probably influenced by age, illness, therapy etc. Only those patients among the aged who were in bad health showed a relatively low humoral booster reaction.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000917:Antibody Formation; D001161:Arteriosclerosis / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000276:immunology; D003920:Diabetes Mellitus / Q000276:immunology; D005265:Femoral Neck Fractures / Q000276:immunology; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology*; D013742:Tetanus / Q000517:prevention & control; D013743:Tetanus Antitoxin / Q000032:analysis; D013745:Tetanus Toxoid / Q000276:immunology*
D013743:Tetanus Antitoxin; D013745:Tetanus Toxoid
T-Zellkinetik und Verlauf der Humoralen Immunantwort nach subkutaner Immunisierung mit Tetanustoxoid-Fluid-Impfstoff.