title: X-14885A, a novel divalent cation ionophore produced by a Streptomyces culture: discovery, fermentation, biological as well as ionophore properties and taxonomy of the producing culture.
abstract: Antibiotic X-14885A is a novel divalent cation ionophore produced by a Streptomyces culture isolated from soil sample collected in Wyoming. Its cation binding sequence has been found to be: Mg2+ greater than Ca2+, Sr2+ greater than Ba2+ much greater than Li+, Na+, Rb+, K+, Cs+.
mesh_terms: D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000187:drug effects; D002413:Cations, Divalent; D002414:Cations, Monovalent; D003470:Culture Media; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D007476:Ionophores / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D011714:Pyrans / Q000302:isolation & purification / Q000633:toxicity; D013302:Streptomyces / Q000254:growth & development* / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents; D002413:Cations, Divalent; D002414:Cations, Monovalent; D003470:Culture Media; D007476:Ionophores; D011714:Pyrans; C039617:antibiotic X 14885A