No elevation of the frequencies of chromosomal alterations as a consequence of handling cytostatic drugs. Analyses with peripheral blood and urine of hospital personnel.
Peripheral blood lymphocytes of hospital personnel handling cytostatic drugs showed no elevation of structural chromosomal aberrations or sister-chromatid exchanges (SCE) over the baseline. The urine of the probands did not induce SCE in peripheral lymphocytes in vitro.
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002869:Chromosome Aberrations; D003434:Crossing Over, Genetic; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000032:analysis; D008297:Male; D010564:Personnel, Hospital; D012449:Safety; D012854:Sister Chromatid Exchange; D014556:Urine / Q000032:analysis
D000970:Antineoplastic Agents