The presence of histamine in Cnidosculus oligandrus (Euphorbiaceae).
1) The presence of histamine in prickles and lead and stem tissues of Cnidosculus oligandrus (Mull. Arg) Pax & Hoffm (Euphorbiaceae) is reported. 2) Prickles on stems and leaves have larger amounts of histamine, as determined by the isolated guinea-pig ileum and by fluorimetry of the condensation product of the histamine and ortho-phthalaldehyde (OPT). 3) Additionally, thin-layer chromatography and the increase of vascular permeability bioassay were used to confirm the presence of histamine.
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects; D002855:Chromatography, Thin Layer; D004155:Diphenhydramine / Q000494:pharmacology; D005260:Female; D005470:Fluorometry; D006168:Guinea Pigs; D006632:Histamine / Q000302:isolation & purification*; D007082:Ileum / Q000502:physiology; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D010936:Plant Extracts / Q000032:analysis*; D013050:Spectrometry, Fluorescence
D010936:Plant Extracts; D006632:Histamine; D004155:Diphenhydramine