title: Pagetoid reticulosis. Histiocyte marker studies.
abstract: Epidermal mononuclear cell infiltrate from three patients with pagetoid reticulosis was examined for the presence of the cytoplasmic markers lysozyme, alpha 1-antitrypsin and alpha 1-antichymotrypsin, using specific antisera and a peroxidase-antiperoxidase technique. Many of the infiltrating cells possessed these markers, indicating that they belonged to the monocyte-macrophage-histiocyte series.
mesh_terms: D000328:Adult; D002918:Chymotrypsin / Q000037:antagonists & inhibitors / Q000378:metabolism; D006644:Histiocytes / Q000201:enzymology / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D008206:Lymphatic Diseases / Q000201:enzymology / Q000473:pathology*; D008264:Macrophages / Q000201:enzymology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000201:enzymology / Q000473:pathology; D009113:Muramidase / Q000378:metabolism; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology*; D000515:alpha 1-Antitrypsin / Q000378:metabolism
chemical_list: D000515:alpha 1-Antitrypsin; D009113:Muramidase; D002918:Chymotrypsin