Occurrence of penicillin-resistant and beta-lactamase-producing Bacteroides species in the oral cavity.
Bacteroides species are known to play an important role in orofacial infections. The present investigation shows that penicillin-resistant Bacteroides species are commonly found in the oral cavity and that their occurrence is related to previous penicillin therapy. Several of the penicillin-resistant isolates were also resistant to erythromycin and/or doxycycline while all strains were sensitive to clindamycin and tinidazole. the penicillin resistance was mainly due to beta-lactamase production. A selective cultivation method for detection of penicillin-resistant Bacteroides is described.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001439:Bacteroides / Q000201:enzymology / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D010403:Penicillin Resistance; D010406:Penicillins / Q000627:therapeutic use; D013997:Time Factors; D001618:beta-Lactamases / Q000096:biosynthesis
D000900:Anti-Bacterial Agents; D010406:Penicillins; D001618:beta-Lactamases