Hb A2-Zagreb or alpha 2 delta 2(125)(H3)Gln replaced by Glu, a new delta chain variant in association with delta beta-thalassemia.
The structural identification of a new delta chain variant is described. The abnormal Hb A2 was found in two members of a family from Zagreb, Yugoslavia. The propositus also had a delta beta-thalassemia heterozygosity.
D000328:Adult; D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D002648:Child; D005260:Female; D014644:Genetic Variation; D006455:Hemoglobins, Abnormal / Q000302:isolation & purification*; D006579:Heterozygote; D006801:Humans; D008297:Male; D010446:Peptide Fragments; D013789:Thalassemia / Q000097:blood*; D015022:Yugoslavia
D006455:Hemoglobins, Abnormal; D010446:Peptide Fragments; C039481:hemoglobin A2 Zagreb