title: Major hemorrhage and perforation due to a solitary cecal ulcer in a patient with end-stage renal failure.
abstract: A case of solitary cecal ulcer with major hemorrhage followed by perforation after treatment with intra-arterial vasopressin in a patient with end-stage renal failure is presented. Though vasopressin has been used with success in the treatment of colonic hemorrhage, caution should be applied in patients with a bleeding cecal ulcer as the vasoconstriction produced by vasopressin may cause perforation in an area whose blood supply is already compromised.
mesh_terms: D002429:Cecal Diseases / Q000150:complications* / Q000473:pathology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications*; D008875:Middle Aged; D011859:Radiography; D014456:Ulcer / Q000150:complications / Q000473:pathology; D014667:Vasopressins / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D014667:Vasopressins