Constitution and absolute stereochemistry of the antibiotic sarubicin A.
By spectral (UV-VIS, IR, NMR, MS and CD) methods the quinone antibiotics sarubicin A and U-58,431 were shown to have identical constitution and stereochemistry. Chiroptical data and their theoretical analysis have settled the common absolute configuration as 5S, 6R, 8R, 10R.
D000900:Anti-Bacterial Agents; D002942:Circular Dichroism; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D009285:Naphthoquinones; D013053:Spectrophotometry
D000900:Anti-Bacterial Agents; D007202:Indicators and Reagents; D009285:Naphthoquinones; C027400:sarubicin A