title: [Pharmacology of lycorine. 1) Effect on biliary secretion in the rat].
abstract: The Authors study pharmacological actions of lycorine, alkaloid of Lycoris radiata. On the basis that anti-inflammatory substances have a choleretic effect, the activity of lycorine on biliary secretion of rats has been investigated. Lycorine, at a dose of 1 mg/kg induces, in rats anaesthetized with urethane (1,2 g/kg i.m.), a marked choleretic effect. This experiment do not define the mechanism responsible for the observed choleresis.
mesh_terms: D047151:Amaryllidaceae Alkaloids; D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010617:Phenanthridines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D047151:Amaryllidaceae Alkaloids; D010617:Phenanthridines; C015330:lycorine
vernacular_title: Studi farmacologici sulla licorina. 1) Effetto sulla secrezione biliare nel ratto.