[EB virus, immunodeficiency, bone marrow aplasia, malignant mononucleosis and sex-linked lymphoproliferative B syndrome (XLP)].
The X-linked lymphoproliferative syndrome may be the model of a EBV-induced immunodeficiency which may lead, in case of T-insufficiency, either to myeloid aplasia, or to a polyclonal proliferation of the malignant, infectious mononucleosis (MI) type or, if it becomes secondarily monoclonal, non-hodgkin lymphoma (LNH).
D001853:Bone Marrow / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000209:etiology* / Q000473:pathology; D007244:Infectious Mononucleosis / Q000150:complications*; D008223:Lymphoma / Q000209:etiology; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D014960:X Chromosome
Virus EBV, immunodeficience, aplasie médullaire, mononucléose maligne et syndrome lymphoprolifératif B lié au sexe (XLP).