title: Observations on the BT PABA/14C-PABA tubeless test of pancreatic function.
abstract: The diagnostic accuracy of the BT PABA/14C-PABA tubeless test of pancreatic function was assessed in a prospective study of 140 patients. Drug or isotopic interference invalidated 16 tests (11.4%). The sensitivity of the PABA/14C excretion index was 76.7% and the specificity 85.7% using the mean -2 SD value of 0.82 as the cut-off point; 74.4% sensitivity and 95.7% specificity using the mean -3 SD value of 0.76. The potential usefulness and limitations of this modern version of the PABA test are discussed.
mesh_terms: D010129:4-Aminobenzoic Acid / Q000652:urine; D062365:Aminobenzoates; D002250:Carbon Radioisotopes; D002908:Chronic Disease; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D010182:Pancreatic Diseases / Q000175:diagnosis*; D010186:Pancreatic Function Tests / Q000379:methods; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D010195:Pancreatitis / Q000175:diagnosis; D011446:Prospective Studies; D062366:para-Aminobenzoates
chemical_list: D062365:Aminobenzoates; D002250:Carbon Radioisotopes; D062366:para-Aminobenzoates; C006717:bentiromide; D010129:4-Aminobenzoic Acid