Salivary urea nitrogen as an index to renal function: a test-strip method.
To investigate the feasibility of using salivary urea nitrogen as an index of renal glomerular filtration rate, we developed and applied a new analytical system consisting of a urease-containing test strip and an automatic reflectance spectrometer. The concentrations of urea nitrogen so determined correlate well (r = 0.93) with concentrations in serum. These preliminary data suggest that our method can be used routinely as a simple and reliable means of detecting abnormalities of renal function.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001961:Bromcresol Green; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007202:Indicators and Reagents; D007215:Indophenol; D007674:Kidney Diseases / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011934:Reagent Strips; D012463:Saliva / Q000032:analysis* / Q000378:metabolism; D014508:Urea / Q000032:analysis* / Q000097:blood; D014510:Urease
D007202:Indicators and Reagents; D011934:Reagent Strips; D007215:Indophenol; D014508:Urea; D001961:Bromcresol Green; D014510:Urease