Seroepidemiological studies on the effects of filarial parasites on infestation of adult T-cell leukemia virus in the Goto Islands, Japan.
Patients with filariasis were commonly observed until 1961-1970 in the Goto Islands, an area where adult T-cell leukemia (ATL) is endemic. The positive rate of antibodies to ATL virus-associated antigen among persons with a high antibody titer to filarial antigen was higher than that among persons with a low antibody titer in both sexes. Thus, filarial parasites might have some promoting effects on ATL virus infection and/or ATL virus proliferation among inhabitants in the endemic areas of filariasis and ATL.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis; D002648:Child; D005260:Female; D005368:Filariasis / Q000150:complications* / Q000276:immunology; D006801:Humans; D007938:Leukemia / Q000150:complications* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012190:Retroviridae / Q000276:immunology*; D013601:T-Lymphocytes
D000914:Antibodies, Viral; D000956:Antigens, Viral