Germinal center cell-derived lymphomas of the skin.
Germinal center cell-derived (GCC) malignant lymphomas are B-cell tumors that represent neoplastic equivalents of normal lymphoid follicles. These lymphomas include, in the Kiel classification, three main types: centrocytic lymphoma, centroblastic-centrocytic lymphoma, and centroblastic lymphoma. We have diagnosed 13 cases of germinal center cell-derived cutaneous lymphomas among 178 evaluated malignant lymphomas of the skin. Some clinical, histologic, and immunologic aspects are discussed in this article.
D000368:Aged; D001402:B-Lymphocytes; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000145:classification / Q000276:immunology / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000145:classification / Q000276:immunology / Q000473:pathology*