Serum uric acid in mild essential hypertension.
The mean serum level of urate and the incidence of hyperuricemia have been found to be normal in 85 patients with untreated essential arterial hypertension without renal failure. On the contrary, the incidence of hyperuricemia has been found to be high in 36 similar patients on a low salt diet and in 19 others who received diuretics. Uricemia decreased in 55 patients on a low salt diet who received hydrazinophthalazine (hydralazine) and in 10 other patients who changed their diet from a low salt diet to a diet supplying normal amounts of salt. These results indicate that essential arterial hypertension does not cause hyperuricemia.
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004039:Diet, Sodium-Restricted; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use; D006973:Hypertension / Q000097:blood* / Q000178:diet therapy / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D014527:Uric Acid / Q000097:blood*
D004232:Diuretics; D014527:Uric Acid; D006830:Hydralazine