title: Megacystis-microcolon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had prune belly syndrome: common pathogenesis?
abstract: A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.
mesh_terms: D000015:Abnormalities, Multiple; D003106:Colon / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010528:Peristalsis; D011535:Prune Belly Syndrome / Q000235:genetics*; D011859:Radiography; D001743:Urinary Bladder / Q000002:abnormalities* / Q000000981:diagnostic imaging