Effect of naftidrofuryl oxalate (Praxilene) on blood flow in the experimental saphenous flap model.
Intravenous administration of naftidrofuryl oxalate (Praxilene) in the dog has shown a significant increase in blood flow into an experimental saphenous flap model (64% p less than 0.05). Further study is needed to show whether a similar increase in blood flow could be produced in an ischaemic flap.
D000818:Animals; D001783:Blood Flow Velocity; D001808:Blood Vessels / Q000187:drug effects; D004285:Dogs; D005663:Furans / Q000494:pharmacology*; D007511:Ischemia; D009257:Nafronyl / Q000494:pharmacology*; D012867:Skin / Q000098:blood supply*; D013524:Surgical Flaps
D005663:Furans; D009257:Nafronyl