The immune response of the mouse to lymphocytic choriomeningitis virus. III. Differences of numbers of cytotoxic T lymphocytes in spleens of mice of different strains.
By use of an accurate procedure for the measurement of relative numbers of murine cytotoxic T lymphocytes (CTL) marked differences of lymphocytic choriomeningitis virus-specific CTL in spleens were found among mouse strains that ranged from low over intermediate and high to very high, suggesting a gradient of responses rather than distinct classes. Differences were also found between mice sharing the major histocompatibility complex.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D005347:Fibroblasts; D006183:H-2 Antigens; D006824:Hybridization, Genetic; D007739:L Cells; D008216:Lymphocytic Choriomeningitis / Q000276:immunology*; D008217:Lymphocytic choriomeningitis virus / Q000276:immunology* / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains; D013154:Spleen / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014779:Virus Replication
D006183:H-2 Antigens