Essential fatty acid deficiency: a suggestion concerning experimental design.
In experiments on essential fatty acid deficiency, various strategems have been used to balance the deficient and control groups for all nutrients except essential fatty acids. We suggest the use of a single fat-free diet for both groups, with essential fatty acids administered parenterally to the control (nondeficient) group once each week.
D000818:Animals; D003872:Dermatitis / Q000209:etiology; D004041:Dietary Fats / Q000008:administration & dosage; D004655:Emulsions; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage; D005228:Fatty Acids, Essential / Q000172:deficiency*; D005526:Food, Formulated; D054709:Lecithins; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D012107:Research Design; D012450:Safflower Oil; D013024:Soybean Oil
D004041:Dietary Fats; D004655:Emulsions; D005217:Fat Emulsions, Intravenous; D005228:Fatty Acids, Essential; D054709:Lecithins; C031435:safflower oil, soybean oil, lecithin emulsion; D013024:Soybean Oil; D012450:Safflower Oil