Gastric epithelial dysplasia and sulphomucin-type intestinal metaplasia.
The HID-AB histologic staining technique, which distinguishes sulphomucin from sialomucin types of intestinal metaplasia, was employed in endoscopic gastric mucosal biopsies to evaluate their frequency of association with epithelial dysplasia. Sulphomucin-type intestinal metaplasia was found in 33% of the cases under observation; moderate or severe dysplasia was only associated with this type of intestinal metaplasia. Its precancerous significance can be ascertained only by means of prospective studies.
D000328:Adult; D000368:Aged; D001706:Biopsy; D004848:Epithelium / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D008679:Metaplasia / Q000473:pathology; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism*; D052116:Sialomucins
D009077:Mucins; D052116:Sialomucins; C012564:sulfomucin