Mitochondria of adult human brown adipose tissue contain a 32 000-Mr uncoupling protein.
Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents.
D002001:Adipose Tissue, Brown / Q000648:ultrastructure*; D000310:Adrenal Gland Neoplasms / Q000032:analysis; D002352:Carrier Proteins; D006801:Humans; D007473:Ion Channels; D008565:Membrane Proteins / Q000032:analysis*; D008928:Mitochondria / Q000032:analysis*; D024101:Mitochondrial Proteins; D010673:Pheochromocytoma / Q000032:analysis; D014475:Uncoupling Agents / Q000032:analysis; D000071256:Uncoupling Protein 1
D002352:Carrier Proteins; D007473:Ion Channels; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D014475:Uncoupling Agents; D000071256:Uncoupling Protein 1