MHC zygosity in the frog, Rana temporaria.
The major histocompatibility complex (MHC) zygosity of the field-collected frogs, Rana temporaria, was detected by progeny testing. Groups of sibling tadpoles were grafted with intrafamilial tail-tip allografts and the ratio of rapidly rejected allografts to slowly rejected ones was estimated. Twenty-five percent of parental frogs appeared to be MHC homozygotes. Thus, MHC homozygosity in natural frog populations seems to be considerably higher than in wild mouse populations.
D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D006084:Graft Rejection; D006720:Homozygote; D008285:Major Histocompatibility Complex; D008297:Male; D011896:Rana temporaria / Q000276:immunology*; D014184:Transplantation, Homologous