Distribution of superoxide dismutase in the ground squirrel (Citellus citellus): effect of the hibernation and arousal.
The activity of superoxide dismutase (SOD) was studied in the liver, kidney, interscapular brown adipose tissue (IBAT), lung, heart and spleen of the active and hibernating ground squirrel (Citellus citellus). One group was examined immediately after the arousal from the hibernation. A considerable activity of this enzyme was found in homogenates of all tissues studied except the lung. This activity was lower in the liver and lung of the ground squirrel than in the rat (P less than 0.01). In the other tissues studied the enzyme activity was about the same level in both animals. In the ground squirrel hibernation didn't produce the significant change in SOD activity, as compared with the active state, except in the spleen. Tested immediately after the arousal, SOD activity was significantly higher in all tissues studied except in the IBAT, as compared with the hibernating ones (P less than 0.01).
D000818:Animals; D001143:Arousal / Q000502:physiology*; D006605:Hibernation; D008297:Male; D051381:Rats; D012589:Sciuridae / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
D013482:Superoxide Dismutase