Redetermination of the rate-limiting step in the activation of factor IX by factor XIa and by factor VIIa/tissue factor. Explanation for different electrophoretic radioactivity profiles obtained on activation of 3H- and 125I-labeled factor IX.
D001921:Brain / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D004789:Enzyme Activation; D005164:Factor IX / Q000378:metabolism*; D005167:Factor VII / Q000378:metabolism*; D015942:Factor VIIa; D005172:Factor XI / Q000378:metabolism*; D015945:Factor XIa; D006801:Humans; D007457:Iodine Radioisotopes; D007700:Kinetics; D046911:Macromolecular Substances; D013925:Thromboplastin / Q000378:metabolism*; D014316:Tritium
D007457:Iodine Radioisotopes; D046911:Macromolecular Substances; D014316:Tritium; D005167:Factor VII; D005164:Factor IX; D005172:Factor XI; D013925:Thromboplastin; D015942:Factor VIIa; D015945:Factor XIa