The effect of charatoxin, 4-methylthio-1,2-dithiolane, on the frog sartorius neuromuscular junction.
The insecticide 4-methylthio-1,2-dithiolane, named charatoxin, blocks the frog muscular twitches elicited through the neuromuscular junction. The activity level and the course of inhibition is comparable to that of 4-dimethyl-amino-1,2-dithiolane, nereistoxin.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D007306:Insecticides / Q000494:pharmacology*; D008387:Marine Toxins / Q000494:pharmacology; D009469:Neuromuscular Junction / Q000187:drug effects*; D010944:Plants; D011896:Rana temporaria; D013876:Thiophenes / Q000494:pharmacology*
D007306:Insecticides; D008387:Marine Toxins; D013876:Thiophenes; C025633:nereistoxin; C040728:charatoxin