[Effect of aggregating agents on the pentosephosphate pathway of carbohydrate metabolism in human blood platelet extracts].
Thrombin inhibits the rate of glucose-6-phosphate and 6-phosphogluconate oxidation. ADP decreases the incorporation of ribose-5-phosphate into metabolism. The effect of adrenaline on the pentose phosphate pathway reactions was not demonstrated. Cell destruction by means of freezing, thawing and treatment with Triton X-100 decreases the rate of the glucose-6-phosphate dehydrogenase reaction to a greater degree as compared with osmotic shock.
D000244:Adenosine Diphosphate / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D004837:Epinephrine / Q000494:pharmacology*; D005615:Freezing; D005636:Fructosephosphates / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D017830:Octoxynol; D009997:Osmotic Pressure; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011092:Polyethylene Glycols / Q000494:pharmacology; D012267:Ribosemonophosphates / Q000378:metabolism; D013403:Sugar Phosphates / Q000378:metabolism; D013917:Thrombin / Q000494:pharmacology*
D005636:Fructosephosphates; D012267:Ribosemonophosphates; D013403:Sugar Phosphates; C020495:sedoheptulose 7-phosphate; D011092:Polyethylene Glycols; C031626:ribose-5-phosphate; D000244:Adenosine Diphosphate; C027618:fructose-6-phosphate; D017830:Octoxynol; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013917:Thrombin; D005947:Glucose; D004837:Epinephrine
Vliianie nekotorykh agregiruiushchikh agentov na pentozofosfatnyĭ put' metabolizma uglevodov v ékstraktakh krovianykh plastinok cheloveka.