title: Analysis and interpretation of data from carcinogenicity and toxicity studies in animals.
abstract: Many chemicals are being tested for carcinogenicity and toxicity in animals. Reports are submitted to government agencies in order to evaluate the safety of chemicals. Personnel generally are not trained to carry out such evaluations. There is no particular system that is being used in these evaluations. The purpose of this paper is to describe a system for the evaluation of carcinogenicity and toxicity studies developed over the past several years.
mesh_terms: D000818:Animals; D001284:Atrophy; D002273:Carcinogens / Q000032:analysis*; D056486:Chemical and Drug Induced Liver Injury; D004305:Dose-Response Relationship, Drug; D005069:Evaluation Studies as Topic; D005260:Female; D007674:Kidney Diseases / Q000139:chemically induced; D007680:Kidney Neoplasms / Q000139:chemically induced; D008113:Liver Neoplasms / Q000139:chemically induced; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D009369:Neoplasms / Q000139:chemically induced / Q000473:pathology; D013223:Statistics as Topic; D013737:Testis / Q000473:pathology; D014116:Toxicology / Q000379:methods*
chemical_list: D002273:Carcinogens