title: [Dexamethasone and corticosterone binding by glucocorticoid-resistant and glucocorticoid-sensitive thymocytes in vitro and in vivo].
abstract: No correlation between the sensitivity of thymocytes to glucocorticoids and the number of glucocorticoid receptors has been revealed in studies carried out in vivo and in vitro. The micromedium of the thymus has been found capable of accumulating glucocorticoid hormones.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003345:Corticosterone / Q000378:metabolism*; D003907:Dexamethasone / Q000378:metabolism*; D004351:Drug Resistance; D005938:Glucocorticoids / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011965:Receptors, Glucocorticoid / Q000378:metabolism; D013601:T-Lymphocytes / Q000378:metabolism*; D013997:Time Factors
chemical_list: D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid; D003907:Dexamethasone; D003345:Corticosterone
vernacular_title: Sviazyvanie gliukokortikoidochuvstvitel'nymi i gliukokortiko-rezistentnymi timotsitami deksametazona i kortikosterona in vitro i in vivo.