[Do non-equilibrium reactions in the glucose-to-triose phosphate pathway exist in the liver?].
The circadian changes in the contents of intermediates of the initial reactions of the glycolytic pathway in pigeon liver were studied. the concentrations of glucose, glucose-6-phosphate, fructose-6-phosphate, fructose-1,6-diphosphate and triose phosphates were found to change synchronously, being maximal at the dark time and minimal during the light daytime. The glycogen content in the liver decreased steadily between 12.00 and 09.00. The diurnal variations in the concentrations of metabolite pairs (glucose and glucose-6-phosphate, glucose-6-phosphate and fructose-6-phosphate, fructose-6-phosphate and fructose-1.6-diphosphate, fructose-1.6-diphosphate and triose phosphates) appeared to correlate significantly. The results obtained suggest that in the liver at least there are no limiting i. e. physiologically non-equilibrium reactions in the carbohydrate metabolic pathway from glucose to triose phosphates.
D000818:Animals; D002940:Circadian Rhythm; D010856:Columbidae; D003624:Darkness; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis; D008027:Light; D008099:Liver / Q000378:metabolism*; D013403:Sugar Phosphates / Q000378:metabolism*; D014306:Trioses / Q000378:metabolism*
D013403:Sugar Phosphates; D014306:Trioses; D005947:Glucose
Imeiutsia li neravnovesnye reaktsii obmena uglevodov ot gliukozy do triozofosfatov v pecheni?