Ketanserin in the treatment of hypertension following coronary artery bypass surgery. A preliminary study.
The possible role of 5-hydroxytryptamine (serotonin) in patients developing hypertension following coronary artery bypass surgery was investigated by intravenous administration of ketanserin, a specific 5-hydroxytryptamine-receptor antagonist. Our findings in the preliminary study indicate that 5-hydroxytryptamine might not play a role in the hypertension seen after coronary artery bypass surgery.
D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D007650:Ketanserin; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use*; D011182:Postoperative Care; D011183:Postoperative Complications
D000959:Antihypertensive Agents; D010880:Piperidines; D007650:Ketanserin