Anaphylactoid reaction to zomepirac.
Circulatory collapse and respiratory arrest occurred in a young woman shortly after taking 200 mg of zomepirac for relief of headache. She had no history of drug hypersensitivity and had tolerated zomepirac without adverse effects 18 months prior to this reaction. The patient was successfully treated and suffered no sequelae.
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced* / Q000503:physiopathology; D004342:Drug Hypersensitivity / Q000503:physiopathology*; D005260:Female; D006801:Humans; D011758:Pyrroles / Q000009:adverse effects*; D012131:Respiratory Insufficiency / Q000139:chemically induced / Q000503:physiopathology; D014046:Tolmetin / Q000009:adverse effects* / Q000031:analogs & derivatives
D011758:Pyrroles; C020549:zomepirac; D014046:Tolmetin