Prolonged survival in chronic lymphocytic leukemia.
An asymptomatic female patient with CLL survived more than 32 years. Her case is compared to that of other known long-term CLL survivors. She had small, well differentiated lymphocytes in the peripheral blood with B-cell characteristics and increased numbers of cells binding surface immunoglobulin (IgM). She is only the second patient known to have survived this long without therapy and without progressive disease. She is also the longest known survivor of documented B-cell CLL.
D000328:Adult; D001402:B-Lymphocytes; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007945:Leukemia, Lymphoid / Q000276:immunology / Q000401:mortality*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes; D013997:Time Factors
D007075:Immunoglobulin M