title: [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology].
abstract: T-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied in the field of obstetrics and gynecology. The following results were obtained. The concentrations of T-1982 in arterial and venous blood and genitalia were measured. The results demonstrated favourable transfer of drug into various internal genital organs. T-1982 was administered to 13 patients. The effectiveness rate was 92.3%, that is to say, excellent in 4 cases, good in 8 cases and poor in 1 case. As for side effect, any noteworthy effect was not observed.
mesh_terms: D000328:Adult; D000368:Aged; D000653:Amniotic Fluid / Q000032:analysis; D002513:Cephamycins / Q000378:metabolism* / Q000627:therapeutic use; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D010053:Ovary / Q000378:metabolism; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy; D014599:Uterus / Q000378:metabolism
chemical_list: D002513:Cephamycins; C035978:cefbuperazone