title: [Biosynthesis and maturation of ribosomal RNA in thymocyte subpopulations of X-irradiated rats].
abstract: A study was made of RNA biosynthesis and maturation in the control and irradiated thymocyte fractions isolated in a ficoll-paque gradient. The post-irradiation impairment of rRNA processing was manifested by the enhancement of pre-rRNA biosynthesis and the increase in 18S rRNA "wastage" during the first hours following X-irradiation. The changes were most pronounced in the thymocyte fraction sedimenting in a gradient zone with the density of above 1.077.
mesh_terms: D000818:Animals; D002499:Centrifugation, Density Gradient; D008297:Male; D012335:RNA, Ribosomal / Q000096:biosynthesis / Q000528:radiation effects*; D011836:Radiation Tolerance; D051381:Rats; D013601:T-Lymphocytes / Q000528:radiation effects*; D013950:Thymus Gland / Q000166:cytology / Q000528:radiation effects
chemical_list: D012335:RNA, Ribosomal
vernacular_title: Biosintez i sozrevanie ribosomnykh RNK v subpopuliatsiiakh timotsitov krys, podvergnutykh rentgenovskomu oblucheniiu.