Capacitance--voltage relationship in phospholipid bilayers containing gangliosides.
Changes in the position of the minimum of the parabolic capacitance-voltage curve allow the measurement of the amount of ganglioside present in artificial bilayers made with phosphatidylcholine-ganglioside mixtures and asymmetrically shielded with Ca2+. The screening effect of the ionic solution must be considered. With ganglioside/phospholipid molar ratios of up to 15%, all glycolipids can be found at the membrane surfaces.
D005732:Gangliosides; D008051:Lipid Bilayers; D008433:Mathematics; D008564:Membrane Potentials; D010713:Phosphatidylcholines; D010718:Phosphatidylserines; D013329:Structure-Activity Relationship
D005732:Gangliosides; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D010718:Phosphatidylserines; C017251:1,2-oleoylphosphatidylcholine