title: [Chromatographic determination of ointment bases and emulsifying agents in European and German pharmacopoeias].
abstract: The ointment bases Lanolinum, Lanae alcoholum unguentum, Zinci unguentum, Polyethylenglycoli unguentum, Unguentum leniens and Unguentum emulsificans, and the emulsifying agents Glyceroli monostearas, Polyethylenglycoli 400 stearas and Polysorbatum 20, 60, 80 were identified by HPTLC and their most important components were determined quantitatively by application of HPLC. The proposed methods of identification are more specific than those described in the monographs of the pharmacopoeias. The obtained results were compared with the nominal values listed in both pharmacopoeias as assays of these bases and emulsifiers are not mentioned, except for glyceroli monostearas.
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D005060:Europe; D005079:Excipients / Q000032:analysis*; D009823:Ointment Bases / Q000032:analysis*; D010592:Pharmaceutic Aids / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D010602:Pharmacopoeias as Topic
chemical_list: D005079:Excipients; D009823:Ointment Bases; D010592:Pharmaceutic Aids; D004364:Pharmaceutical Preparations
vernacular_title: Chromatographische Bestimmung von Salbengrundlagen und Emulgatoren des Europäischen und Deutschen Arzneibuches.