T-cell chronic lymphocytic leukemia in a patient with invasive thymoma in remission with chemotherapy.
This is a case report of a patient with invasive thymoma. Subsequently to radiotherapy and steroids, a combination chemotherapy of cis-platinum (CDDP) and doxorubicin was tested with good results. The patient later developed a chronic lymphocytic leukemia (CLL); morphologically and cytochemically a T-CLL with skin localizations, hepatomegaly, and a high leukocyte count.
D000328:Adult; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D007945:Leukemia, Lymphoid / Q000209:etiology*; D007958:Leukocyte Count; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D013601:T-Lymphocytes; D013945:Thymoma / Q000188:drug therapy* / Q000532:radiotherapy; D013953:Thymus Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy
D004317:Doxorubicin; D002945:Cisplatin