title: Thyroid-epididymal relationship. I. Influence of hypothyroidism on epididymal lipids.
abstract: The influence of thyroidectomy on the lipid composition of caput and cauda epididymides have been studied. The analysis was conducted in epididymal tissues free from fluids and sperm. A general tendency towards accumulation of epididymal lipids was observed in hypothyroid rats. Hypothyroidism also brought about a differential regional response, which may be age-related. The existence of a relationship between triacylglycerols, phospholipids and diacylglycerols has been suggested. Since immediate thyroxine replacement to thyroidectomised rats maintained epididymal lipids at control levels, it is concluded that hypothyroidism has a definite influence on the epididymal lipid composition.
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002784:Cholesterol / Q000378:metabolism; D004822:Epididymis / Q000378:metabolism*; D005989:Glycerides / Q000378:metabolism; D007037:Hypothyroidism / Q000378:metabolism*; D050356:Lipid Metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000502:physiology
chemical_list: D005989:Glycerides; D010743:Phospholipids; D002784:Cholesterol