title: T-cell mediated immunity in food allergy.
abstract: There are many T-cells within the intestinal mucosa, and histopathology, applied to biopsies of intestinal mucosa taken before and after food reintroduction, provides information on possible cell-mediated immunity to foods within the gut. Food sensitive enteropathies occur in man and in domestic animals, particularly in the young. Our hypothesis is that these are related to a relative deficiency of suppressor T-cells. There is no evidence that T-cell-mediated immunity to foods plays a part in severe atopic eczema, even in patients with clinical evidence of associated food allergy and high titres of IgE antibodies to foods.
mesh_terms: D000328:Adult; D000818:Animals; D001706:Biopsy; D002446:Celiac Disease / Q000276:immunology; D003876:Dermatitis, Atopic / Q000276:immunology; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000032:analysis; D007583:Jejunum / Q000473:pathology; D008213:Lymphocyte Activation; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007073:Immunoglobulin E