Some specific predictions and experiments on single myofibrillar mechanics.
The length-tension relationship of myofibrils approximately 50 sarcomeres long from skinned single atrial cells was measured. All sarcomeres were observable throughout the experiments. The tension developed at submaximal Ca2+ concentrations consistently increased with the sarcomere length.
D000818:Animals; D016275:Atrial Function; D002118:Calcium / Q000494:pharmacology*; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects; D009210:Myofibrils / Q000187:drug effects / Q000502:physiology*; D011892:Rana catesbeiana; D012518:Sarcomeres / Q000187:drug effects / Q000502:physiology
D002118:Calcium