Granular corneal dystrophy with late manifestation.
Ninety-two cases of granular corneal dystrophy, most of them belonging to 5 pedigrees are described. The age of manifestation in this Finnish type of granular dystrophy is first in the end of the second decade, and visual acuity is in mean normal through the whole life. An autopsy study showed no changes outside cornea elsewhere in the eyeball. In one family with granular dystrophy, another type of dystrophy, hereditary fleck dystrophy of the cornea, was accidentally found.
D000328:Adult; D000368:Aged; D001112:Arcus Senilis / Q000235:genetics / Q000473:pathology; D003315:Cornea / Q000294:innervation / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000235:genetics* / Q000473:pathology; D003459:Crystallins; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000473:pathology; D010375:Pedigree; D014792:Visual Acuity
D003459:Crystallins