title: Carcinomas of the nose and paranasal sinuses in former employees of a sinter plant at Copper Cliff, Ontario.
abstract: The former employees of the nickel sintering plant in Copper Cliff, Ontario have a high incidence of carcinoma of the nose and paranasal sinuses. These tumors usually are anaplastic or undifferentiated carcinoma which are aggressive locally and tend to metastasize widely. The prognosis with this disease is poor. It is felt that the occurrence of this small occupational group with a greatly increased incidence of a relatively uncommon carcinoma, merits further investigation.
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000139:chemically induced* / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced / Q000453:epidemiology; D004781:Environmental Exposure; D006801:Humans; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D009669:Nose Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000453:epidemiology; D009864:Ontario; D010255:Paranasal Sinus Neoplasms / Q000139:chemically induced* / Q000453:epidemiology
chemical_list: D009532:Nickel