Nasal entomophthoromycosis in Nigerian Igbos.
The clinical and epidemiological pattern of nasal entomophthorosis due to Conidiobolus coronatus, and its histological and mycological features in 13 Igbo patients are described. The disease occurs in an endemic fashion within the hinterland of the Igbo enclave, the riverine areas appearing somewhat exempt. The disease as seen here is probably of the same low virulence in man as reported from other parts of the world. It is likely that the few florid cases seen were due to neglect rather than to more aggressive behaviour. Our experience with these patients would lead us to adopt septrin as the drug of choice in the management of future cases.
D000328:Adult; D004338:Drug Combinations / Q000627:therapeutic use; D004773:Entomophthora; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy; D009549:Nigeria; D009668:Nose Diseases / Q000175:diagnosis / Q000188:drug therapy; D011193:Potassium Iodide / Q000627:therapeutic use; D011446:Prospective Studies; D013420:Sulfamethoxazole / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D004338:Drug Combinations; D011193:Potassium Iodide; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole