HLA-B27 and ankylosing spondylitis in the Mexican Mestizo population.
Two previous surveys of ankylosing spondylitis (AS) in Mexican Mestizos found HLA-B27 frequencies of 68.6% and 78% and a relative risk (RR) of 37.05 and 120.88, respectively. We examined an additional group of Mexican Mestizos with AS and found an HLA-B27 frequency of 80.77% and a RR of 99.24. Our results are statistically comparable to the previous studies, and they suggest that the Mexican Mestizo is similar to the Spaniard in regards to AS and HLA-B27 association.
D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015796:HLA-B27 Antigen; D006801:Humans; D007198:Indians, North American; D008297:Male; D008800:Mexico / Q000208:ethnology; D012306:Risk; D013167:Spondylitis, Ankylosing / Q000235:genetics / Q000276:immunology*
D006680:HLA Antigens; D015796:HLA-B27 Antigen