[Dependence of the rate of development of Zenker's necrosis in the fibers of the frog sartorius muscle on the concentration of chloral hydrate, urea and urethane].
The spreading necrosis in dissected m. sartorius of Rana temporaria changes its speed in the phasic mode in relation to the concentrations of chloral hydrate, urea and uretan, added to the Ringer solution. The number and size of the phases are also dependent on the temperature and the initial physiological state. The concentrations of the above chemicals decelerating necrosis are 2-4 times less than those that increase the survival time of isolated muscles.
D000818:Animals; D002697:Chloral Hydrate / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D009132:Muscles / Q000187:drug effects* / Q000473:pathology; D009336:Necrosis; D011896:Rana temporaria; D013696:Temperature; D014508:Urea / Q000494:pharmacology*; D014520:Urethane / Q000494:pharmacology*
D014520:Urethane; D002697:Chloral Hydrate; D014508:Urea
Zavisimost' skorosti razvitiia tsenkerovskogo nekroza v voloknakh portniazhnoĭ myshtsy liagushki ot kontsentratsii khloralgidrata, mocheviny i uretana.