Pheochromocytomas and ultimobranchial (C-cell) neoplasms in the bull: evidence of autosomal dominant inheritance in the Guernsey breed.
Pheochromocytomas and ultimobranchial (C-cell) neoplasms were diagnosed at a high frequency in a family of Guernsey bulls. The incidence supported the hypothesis of autosomal dominant inheritance of the neoplasms. These two neoplasms also occur in man as multiple endocrine adenomatosis type 2, which has autosomal dominant inheritance.
D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000235:genetics*; D008297:Male; D010375:Pedigree; D010673:Pheochromocytoma / Q000235:genetics / Q000662:veterinary*; D013964:Thyroid Neoplasms / Q000235:genetics / Q000662:veterinary*; D014460:Ultimobranchial Body