[Tumors induced by 1,2-dimethylhydrazine in hybrid mice with the pituitary gland transplanted in the kidney].
1,2-Dimethylhydrazine (DMH) decreased the incidence of tumors in hypophyseal isografts in hybrid mice (CBA X C57BL/6)F1 and prevented the development of mammary tumors. In mice bearing hypophyseal isografts, there was a decrease in the incidence of DMH-induced hemangiomas of the ovary. The same mice showed no alterations in the incidence of DMH-induced uterine sarcomas, tumors of the large intestine, anal region and liver.
D019813:1,2-Dimethylhydrazine; D000818:Animals; D001005:Anus Neoplasms / Q000139:chemically induced; D002273:Carcinogens; D003110:Colonic Neoplasms / Q000139:chemically induced; D004127:Dimethylhydrazines; D005260:Female; D006824:Hybridization, Genetic; D007668:Kidney; D008113:Liver Neoplasms / Q000139:chemically induced; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced; D008763:Methylhydrazines; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D010051:Ovarian Neoplasms / Q000139:chemically induced; D010902:Pituitary Gland / Q000637:transplantation; D010911:Pituitary Neoplasms / Q000139:chemically induced; D011388:Prolactin / Q000502:physiology*; D014594:Uterine Neoplasms / Q000139:chemically induced
D002273:Carcinogens; D004127:Dimethylhydrazines; D008763:Methylhydrazines; D011388:Prolactin; D019813:1,2-Dimethylhydrazine
Opukholi, indutsirovannye 1,2-dimetilgidrazinom u gibridnykh mysheĭ s transplantatom gipofiza v pochku.