title: Immunological relationship between peroxidases in eosinophils, uterus and other tissues of the rat.
abstract: A rabbit antibody against purified pig intestinal peroxidase was shown by means of Western blotting and immunodetection to bind to peroxidases in various rat tissues, including eosinophils, uterus, uterine fluid and mammary tumours, and also to bind to bovine lactoperoxidase. The peroxidase in all rat tissues had an Mr of 53 000, except for uterine fluid, in which the cross-reacting band had an Mr of 80 000. The results indicate that while some of the peroxidase present in uterine tissue could be derived from eosinophils, the enzyme secreted into the lumen of the uterus is likely to have a different origin. They also suggest that mammary tumour peroxidase could originate from infiltration by eosinophils.
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000201:enzymology; D004591:Electrophoresis, Polyacrylamide Gel; D004804:Eosinophils / Q000201:enzymology*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D007784:Lactoperoxidase / Q000276:immunology; D008325:Mammary Neoplasms, Experimental / Q000201:enzymology; D010544:Peroxidases / Q000276:immunology*; D051381:Rats; D011919:Rats, Inbred Strains; D014599:Uterus / Q000187:drug effects / Q000201:enzymology*
chemical_list: D004958:Estradiol; D007784:Lactoperoxidase; D010544:Peroxidases