title: [Relation between plasma levels of 8-methoxypsoralen and the phototoxic effect].
abstract: Plasma concentrations of 8-MOP were studied in 6 subjects at three dose levels and the minimal phototoxic dose determined after 60, 120 and 180 min. Although there is an inverse correlation between these two values, none of the eight mathematical expressions examined gave a perfect fit in all cases.
mesh_terms: D004305:Dose-Response Relationship, Drug; D006801:Humans; D008730:Methoxsalen / Q000008:administration & dosage / Q000032:analysis*; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013997:Time Factors
chemical_list: D008730:Methoxsalen
vernacular_title: Relations entre les taux plasmatiques du 8-méthoxypsoralène et l'effet phototoxique.