title: [Tissue burden with exogenous trace elements caused by roentgen contrast media in bone cements].
abstract: In 44 patients undergoing a change of total hip prosthesis, made of Co-Cr alloy and at one point with a Refobacin-Palacos chain we analyzed samples of the hip joint capsule and fascia lata. Using Instrumental Neutron Activation Analysis (INAA) up to 18 elements were analyzed. The findings demonstrate that the tissues in the surroundings as well as in direct contact with the total hip prosthesis are burdened by corrosion products of the alloy and by decomposition of the bone cement. The decomposition of bone cement can be shown in the extraordinary high concentration of Barium, Zirconium and Hafnium which are added to Bone Cements as X-ray contrast. Microscopic findings at the same time complete and confirm the trace element analyses.
mesh_terms: D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000009:adverse effects*; D003287:Contrast Media / Q000009:adverse effects*; D004338:Drug Combinations / Q000009:adverse effects; D005260:Female; D005839:Gentamicins / Q000009:adverse effects; D006621:Hip Joint / Q000032:analysis / Q000187:drug effects*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008768:Methylmethacrylates / Q000009:adverse effects*; D008875:Middle Aged; D009501:Neutron Activation Analysis; D014131:Trace Elements / Q000032:analysis*
chemical_list: D001843:Bone Cements; D003287:Contrast Media; D004338:Drug Combinations; D005839:Gentamicins; D008768:Methylmethacrylates; D014131:Trace Elements; C030159:gentamicin-polymethylmethacrylate bead
vernacular_title: Gewebebelastung mit körperfremden Spurenelementen durch Röntgenkontrastmittel der Knochenzemente.