A radiographic model for simulating rheumatoid erosions.
Lesions were mechanically created in bone specimens to find a radiographic model for skeletal disease. Drilling, sawing, and filing of the bones did not satisfactorily simulate skeletal pathology. Chipping of the juxta-articular cortex resulted in cortical defects that closely resemble rheumatoid erosions. The radiographs of 25 patients with rheumatoid arthritis were reviewed using optical magnification to determine the size and distribution of actual rheumatoid erosions. Using the pattern of erosions in the patient population, lesions can be distributed in varying sizes to produce a radiographic model for rheumatoid erosions. This model can be used for observer performance studies and to evaluate imaging technology.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging*; D005260:Female; D005384:Finger Joint / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging; D008875:Middle Aged; D008961:Models, Structural; D011859:Radiography