[Effect of MEA on the accumulation of DNA breaks in Bac. stearothermophilus irradiated with gamma and ultraviolet rays and treated with nitrosomethylurea].
beta-Mercaptoethylamine (MEA) decreased the accumulation of enzymatic single- and double-strand breaks in DNA of thermophilic bacteria exposed to gamma- and UV-radiation and treated with N-nitroso-N-methylurea. The protective effect of MEA, as registered according to accumulation of single-strand and double-strand breaks in DNA of Bac. stearothermophilus immediately after irradiation and after 30 min postirradiation incubation, was similar.
D003037:Cobalt Radioisotopes; D004269:DNA, Bacterial / Q000528:radiation effects*; D005720:Gamma Rays; D001411:Geobacillus stearothermophilus / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D008624:Mercaptoethylamines / Q000494:pharmacology*; D008770:Methylnitrosourea / Q000494:pharmacology*; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D014466:Ultraviolet Rays
D003037:Cobalt Radioisotopes; D004269:DNA, Bacterial; D008624:Mercaptoethylamines; D009607:Nitrosourea Compounds; D011837:Radiation-Protective Agents; D008770:Methylnitrosourea
Vliianie MEA na nakoplenie razryvov v DNK Bac. stearothermophilus, obluchennykh gamma-, UF-radiatsieĭ i obrabotannykh nitrozometilmochevinoĭ.