Transplantation of embryonic spinal and cerebral tissue to sciatic nerves of adult rats.
Neurons and glia in spinal or cerebral tissue removed from young rat embryos survived for months after subperineurial implantation in the sciatic nerve of isogenous rats. With HRP tracing, axons from a few grafted neurons were demonstrated to grow distally into host nerves.
D000818:Animals; D002540:Cerebral Cortex / Q000196:embryology / Q000637:transplantation*; D006085:Graft Survival; D008854:Microscopy, Electron; D051381:Rats; D011917:Rats, Inbred Lew; D013116:Spinal Cord / Q000196:embryology / Q000637:transplantation*