Cutaneous T-lymphocyte lymphoma in association with multiple myeloma.
We report a case of cutaneous T-lymphocyte lymphoma in which multiple myeloma, a B-lymphocyte neoplasm, developed. We also review the emerging evidence on the immunoregulatory capacity of neoplastic T lymphocytes. Our case clinically supports the notion that neoplastic T lymphocytes may sometimes express helper activity for a specific B-lymphocyte clone (idiotype-specific helper function).
D000368:Aged; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*; D008466:Mechlorethamine / Q000627:therapeutic use; D009101:Multiple Myeloma / Q000276:immunology / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology
D008466:Mechlorethamine