Radiosensitivity of human T-lymphocytes proliferating in long term culture.
A method is described for determining the radiation sensitivity of dividing human T-lymphocytes in long-term culture. The results are fitted to a single-hit multi-target model. For cobalt-60 gamma radiation Do values of cells from five normal individuals range from 0.99 to 1.37 Gy with an overall Do of 1.09 Gy, and the extrapolation numbers range from 1.20 to 1.71 with an overall extrapolation number of 1.42.
D002455:Cell Division; D002470:Cell Survival / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D011836:Radiation Tolerance; D013601:T-Lymphocytes / Q000528:radiation effects*
D003037:Cobalt Radioisotopes