[Effect of space flight on the Kosmos-1129 biosatellite on enzyme activity of the rat liver].
After the 18.5 day Cosmos-1129 flight the activity of 7 glucocorticoid-stimulated enzymes of the rat liver was measured. Immediately postflight the activity of tyrosine aminotransferase, tryptophan pyrolase and serine dehydrogenase increased. These enzymes rapidly (within several hours) react to increased glucocorticoids. The activity of aspartate and alanine aminotransferases also increased. These enzymes require many days of a continuous effect of glucocorticoids. The glycogen concentration in the rat liver also grew. At R + 6 the activity of tryptophan pyrolase and serine dehydrogenase decreased and that of the other enzymes returned to normal. The immobilization stress applied postflight led to an increased activity of tyrosine aminotransferase and tryptophan pyrolase. This study gives evidence that after space flight rats are in an acute stress state, evidently, produced by the biosatellite recovery.
D000818:Animals; D001835:Body Weight; D008099:Liver / Q000201:enzymology*; D008297:Male; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D013026:Space Flight; D013312:Stress, Physiological / Q000201:enzymology; D014586:USSR
Vliianie kosmicheskogo poleta na biosputnike Kosmos-1129 na aktivnost' riada fermentov v pecheni krys.