Recurrent inversion of the puerperal uterus managed with 15(s)-15-methyl prostaglandin F2 alpha and uterine packing.
The present report describes an unusual case of recurrent puerperal uterine inversion causing major postpartum hemorrhage. Blood replacement, oxytocin, and ergot therapy along with manual reduction failed to prevent immediate recurrence, but treatment with 15(S)-15-methyl prostaglandin F2 alpha (Prostin 15M) and uterine packing were successful. It is recommended that 15(S)-15-methyl prostaglandin F2 alpha be available in all obstetric suites for the management of similar emergencies.
D000328:Adult; D002260:Carboprost / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008722:Methods; D006473:Postpartum Hemorrhage / Q000628:therapy; D011247:Pregnancy; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D011644:Puerperal Disorders / Q000628:therapy*; D012008:Recurrence; D014591:Uterine Diseases / Q000628:therapy*; D014592:Uterine Hemorrhage / Q000209:etiology
D011461:Prostaglandins F, Synthetic; D002260:Carboprost