title: [Mechanism of the glutamate dehydrogenase reaction].
abstract: The data concerning the chemical and kinetic mechanisms of the glutamate dehydrogenase reaction have been reviewed. Based on the differences between two catalytically active glutamate dehydrogenase conformations induced by the substrates as well as on some other evidence, it has been proposed that the amino groups of lysine residues 27 and 126 in the beef liver enzyme are interchangeable depending on the direction of the glutamate dehydrogenase reaction.
mesh_terms: D000818:Animals; D001665:Binding Sites; D002417:Cattle; D005969:Glutamate Dehydrogenase / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D011487:Protein Conformation
chemical_list: D005969:Glutamate Dehydrogenase
vernacular_title: Mekhanizm glutamatdegidrogenaznoĭ reaktsii.