Effects of electroconvulsive therapy on mood, parkinsonism, and tardive dyskinesia in a depressed patient: ECT and dopamine systems.
A patient suffering from delusional depression, Parkinson's disease, and tardive dyskinesia (TD) exhibited a marked improvement in mood and parkinsonian symptoms following electroconvulsive therapy (ECT). In contrast, her TD symptoms worsened. The inverse relation between the intensity of TD symptoms on the one hand and the parkinsonian and depressive symptoms on the other is discussed with respect to ECT's effect on central dopaminergic systems.
D000368:Aged; D001921:Brain / Q000378:metabolism; D003702:Delusions / Q000628:therapy; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D004298:Dopamine / Q000378:metabolism; D004409:Dyskinesia, Drug-Induced / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006220:Haloperidol / Q000009:adverse effects; D006801:Humans; D010302:Parkinson Disease, Secondary / Q000139:chemically induced / Q000628:therapy*; D011954:Receptors, Dopamine / Q000378:metabolism*
D011954:Receptors, Dopamine; D006220:Haloperidol; D004298:Dopamine