Vascular resistance during cardiopulmonary bypass. Its effect on cardiac performance in the immediate post-bypass period.
A clinical study was undertaken to measure changes in systemic vascular resistance during cardiopulmonary bypass in 56 adults. Forty-five patients showed a rise in systemic vascular resistance and 77% required no inotropic support in the immediate post-bypass period. Eleven of the 33 patients undergoing valve replacement surgery showed only a small increase or an actual decrease in systemic vascular resistance and required inotropic support. These results were statistically significant. Factors affecting cardiac performance are discussed.
D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006350:Heart Valve Prosthesis; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011184:Postoperative Period; D013268:Stimulation, Chemical; D013997:Time Factors; D014655:Vascular Resistance
D004837:Epinephrine