Colony promoting activity and its target 'pre-CFUc' in genetically anemic mice of W/Wv genotype.
Incubation of bone marrow cells with supernatant from long-term cultures of bone marrow cells increases the number of granulocyte-macrophage progenitor cells. This study reveals the presence of target cells of the colony promoting activity (CPA) in W/Wv mouse marrow. It is also shown that CPA does not stimulate erythroid colony formation in vitro.
D000740:Anemia / Q000235:genetics* / Q000473:pathology; D000818:Animals; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D003115:Colony-Stimulating Factors / Q000502:physiology*; D005838:Genotype; D006098:Granulocytes / Q000166:cytology; D008264:Macrophages / Q000166:cytology; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*
D003115:Colony-Stimulating Factors