title: Local thrombolytic therapy for subclavian and axillary vein thrombosis. Treatment of the thoracic inlet syndrome.
abstract: Four patients with primary subclavian-axillary vein thrombosis are described. Each patient received local thrombolytic therapy, resulting in reestablishment of antegrade flow via the axillary and subclavian veins. An intrinsic venous abnormality (perimural fibrosis and/or intimal dissection) identified at the first rib-clavicle junction (subclavian-axillary vein junction) was thought to be responsible for the thrombosis. One of the four patients subsequently underwent a surgical venous bypass of the abnormal segment, and a second underwent percutaneous transluminal angioplasty.
mesh_terms: D000328:Adult; D001367:Axillary Vein; D002404:Catheterization; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D005082:Physical Exertion; D011859:Radiography; D013300:Streptokinase / Q000008:administration & dosage; D013350:Subclavian Vein; D013577:Syndrome; D009626:Terminology as Topic; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator