Hyperparathyroidism in the old age.
In a well-defined geriatric population the prevalence of primary hyperparathyroidism was 1.5%. From a clinical material consisting of 400 patients treated surgically for primary hyperparathyroidism during a 10-year period 158 patients (38%) above the age of 64 were studied. Neuromuscular symptoms were present in 80%, renal insufficiency or kidney stones in each 16%, constipation and/or anorexia in 38%. 10% were considered clinically asymptomatic. In 80% the primary hyperparathyroidism was caused by a solitary adenoma. Normocalcaemia was achieved in 94%. Hypocalcaemia requiring vitamin D treatment occurred in 3%, and in 2% hypercalcaemia persisted or recurred. All of these had multiglandular parathyroid disease. The therapeutic effect of the surgical treatment was considered good or fair in most of the cases. No mortality occurred. Primary hyperparathyroidism occurs with a high prevalence in the elderly. It can be treated successfully by surgical therapy with a low cost of morbidity, mortality and medical care.
D000236:Adenoma / Q000175:diagnosis* / Q000601:surgery; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis; D006961:Hyperparathyroidism / Q000175:diagnosis* / Q000601:surgery; D006965:Hyperplasia / Q000473:pathology; D006996:Hypocalcemia / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010279:Parathyroid Diseases / Q000473:pathology; D010282:Parathyroid Neoplasms / Q000175:diagnosis* / Q000601:surgery