Evolution of serum C3, IgG, IgA and IgM levels of healthy mothers and their mature newborns during the early neonatal period.
Susceptibility to infections is most pronounced during the perinatal period. The main characteristic feature of the clinical course is a proneness to generalisation; this can be attributed to immaturity of the immune system. In addition to a series of laboratory parameters, quick and exact determinations of immunoglobulins and complement fractions repeatedly performed within a short time may be useful in confirming a suspected infection and in following the course of the disease. In order to establish the normal basal levels and the dynamics of changes 30 mothers, all healthy, having no abnormality during pregnancy or shortly after delivery, and their healthy mature neonates were examined for IgG, IgA, IgM and C3 serum levels. These basal values are useful in judging the parameters under pathological conditions.
D003176:Complement C3 / Q000032:analysis*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D007231:Infant, Newborn; D008297:Male; D049590:Postpartum Period; D011247:Pregnancy
D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins