Incidence and prognosis of Haemophilus influenzae meningitis in children in a Swedish region.
Haemophilus influenzae meningitis in children 0 to 15 years old was studied retrospectively in a defined region of southwest Sweden from 1971 through 1980; 147 patients with culture-verified H. influenzae meningitis were found. Sixty-seven of them were younger than 18 months and would not have been protected by a purified H. influenzae b polysaccharide vaccine. The age-specific yearly incidence was 27 per 100,000 in the 0- to 4-year age group, 4 per 100,000 in the 5- to 9-year age group and 1 per 100,000 in the 10- to 15-year age group. Predisposing factors were found in only three patients. Two patients died, 3 developed severe neurological sequelae and 19 developed irreversible auditory impairment.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000382:microbiology; D011379:Prognosis; D012189:Retrospective Studies; D012621:Seasons; D013548:Sweden