The compartment model for chronically implanted voltammetric electrodes in the rat brain.
Experimental properties of the peaks obtained with carbon paste electrodes and microprocessor-based linear sweep voltammetry in the rat brain have been compared with those predicted by a theoretical treatment of the problem which we have recently developed. This comparison indicates that the electrodes are situated in a restricted compartment and that the oxidation of ascorbate under these conditions is irreversible. Examples of how this situation has been exploited to improve the voltammograms obtained are given.
D000818:Animals; D001921:Brain / Q000502:physiology*; D004567:Electrodes, Implanted; D008959:Models, Neurological; D051381:Rats; D013997:Time Factors