title: Aromatization: important for testosterone's developmental influences on the neurocircuits mediating cervically stimulated prolactin secretion in the female rat.
abstract: Adult female rats treated neonatally with testosterone or estrogen fail to respond to cervical stimulation with episodic prolactin release. The developmental action of testosterone is inhibited by co-administration of 1,4,6-androstatriene-3,17-dione at a dose sufficient to inhibit the testosterone-induced rise in estrogen receptors in limbic brain cell nuclei. These data suggest the importance of aromatization for testosterone action.
mesh_terms: D000818:Animals; D002584:Cervix Uteri; D003345:Corticosterone / Q000097:blood; D005260:Female; D007986:Luteinizing Hormone / Q000097:blood; D011247:Pregnancy; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D013739:Testosterone / Q000502:physiology*
chemical_list: D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D003345:Corticosterone