Regulation by sex hormones of serum levels of contrapsin and alpha 1-antiprotease in the mouse.
Serum contrapsin and alpha 1-antiprotease levels were higher in males than in females in ten inbred mouse strains tested. The levels of both proteins were diminished by orchiectomy but increased by testosterone administration to females. Estradiol administration to intact females caused a marked elevation in contrapsin level but a decrease in alpha 1-antiprotease level.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D015843:Serpins; D012737:Sex Factors; D013045:Species Specificity; D013739:Testosterone / Q000494:pharmacology*; D013997:Time Factors; D014361:Trypsin Inhibitors / Q000097:blood*; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
D015843:Serpins; D014361:Trypsin Inhibitors; D000515:alpha 1-Antitrypsin; D013739:Testosterone; D004958:Estradiol; C033691:contrapsin