Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte-macrophage colony stimulating factor.
DNA clones specifying the murine granulocyte-macrophage colony stimulating factor have been isolated. This haematopoietic growth factor is encoded by a unique gene specifying a messenger RNA of 1,200 nucleotides and a polypeptide of 118 amino acids. It bears no structural similarity to the functionally related factor, interleukin-3, described recently.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D003115:Colony-Stimulating Factors / Q000235:genetics*; D004247:DNA / Q000378:metabolism*; D005260:Female; D005333:Fetus; D005796:Genes; D006133:Growth Substances / Q000235:genetics; D007700:Kinetics; D008099:Liver / Q000502:physiology; D008168:Lung / Q000378:metabolism; D051379:Mice; D009865:Oocytes / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic; D014981:Xenopus
D003115:Colony-Stimulating Factors; D006133:Growth Substances; D012333:RNA, Messenger; D004247:DNA