title: Accommodation of skeletal muscle in rats under hypoxic conditions induced by tourniquet.
abstract: Resting membrane potential (RMP) and indexes of accommodation (IA) were obtained from the brachioradialis muscle in rats subjected to 2 or 5 h of bilateral hindlimb tourniquet. The results showed a highly significant increase in muscular IA with a return to the control values for the rats with 2 h of tourniquet, while the increased in the IA is maintained all the survival period in the rats with 5 h of tourniquet. The velocity of increasing of the IA bears a direct relationship to the outcome of the injury. A decrease in the RMP of the brachioradialis muscle and an increase in the extracellular K+ and H+ was also observed. The early differences in the behavior of the accommodation parameter allowed a clear differentiation of the rats which survived the tourniquet shock from those who finally died.
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D006614:Hindlimb / Q000098:blood supply; D007511:Ischemia; D008297:Male; D008564:Membrane Potentials; D009119:Muscle Contraction; D009132:Muscles / Q000098:blood supply / Q000503:physiopathology*; D010100:Oxygen; D051381:Rats; D011919:Rats, Inbred Strains; D012769:Shock / Q000503:physiopathology*; D014111:Tourniquets
chemical_list: D010100:Oxygen