title: Rectal insemination modifies immune responses in rabbits.
abstract: Weekly deposition of pooled rabbit semen into the rectum in healthy male rabbits resulted in the appearance of immune complexes and antibodies to sperm and to peripheral blood lymphocyte antigens. It also led to a decreased ability to mount a humoral immune response to T lymphocyte-dependent antigens, keyhole limpet hemocyanin, and sheep red blood cells. These findings suggest that repeated rectal deposition of semen may compromise some aspects of the immune system.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D000936:Antigen-Antibody Complex; D004912:Erythrocytes / Q000276:immunology; D005677:G(M1) Ganglioside; D006028:Glycosphingolipids / Q000276:immunology; D006433:Hemocyanins / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis; D007314:Insemination; D007694:Killer Cells, Natural / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D011817:Rabbits; D012007:Rectum; D012661:Semen / Q000276:immunology*; D013094:Spermatozoa / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors
chemical_list: D000906:Antibodies; D000936:Antigen-Antibody Complex; D006028:Glycosphingolipids; D007136:Immunoglobulins; D005677:G(M1) Ganglioside; C018835:asialo GM1 ganglioside; D006433:Hemocyanins