Postpartum autoimmune thyroid disorder associated with HLA-DR4?
Thirteen Danish women with postpartum thyroiditis were HLA-A, B, C and -DR typed. Nine of ten unrelated probands were DR4-positive which is significantly (corrected p = .01) different from the frequency (34.7%) of this antigen in unrelated controls.
D001327:Autoimmune Diseases / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D006801:Humans; D007037:Hypothyroidism / Q000276:immunology; D011247:Pregnancy; D011644:Puerperal Disorders / Q000276:immunology*; D013959:Thyroid Diseases / Q000276:immunology*; D013966:Thyroiditis / Q000276:immunology
D006680:HLA Antigens; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II