Nutrient intake and its association with high-density lipoprotein and low-density lipoprotein cholesterol in selected US and USSR subpopulations. The US-USSR Steering Committee for Problem Area I: The pathogenesis of atherosclerosis.
Nutrient intake levels and the associations of the nutrients with high-density lipoprotein and low-density lipoprotein cholesterol were studied using cross-sectional data from middle-aged US and USSR men seen at visit 2 of the Lipid Research Clinics Prevalence Study. Differences in nutrient intake in the two countries were small, but statistically significant. The US sample had a higher mean intake of protein, polyunsaturated and monounsaturated fatty acids, and a higher P/S ratio. The USSR sample had higher mean intake of saturated fatty acids, carbohydrate, complex carbohydrate, and sucrose. Correlations between the nutrients and high-density lipoprotein cholesterol were weak and consistently negative for fatty acids, total fat, carbohydrate and its components, and positive for ethanol. The correlations between nutrient intake and low-density lipoprotein cholesterol were even weaker. After adjusting for other factors, nutrient intake had an independent association with high-density lipoprotein cholesterol. Ethanol and carbohydrate showed the strongest association. Nutrient intake also had a modest independent association with low-density lipoprotein cholesterol.
D000428:Alcohol Drinking; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology*; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003430:Cross-Sectional Studies; D005247:Feeding Behavior; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D012306:Risk; D014586:USSR; D014481:United States
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D002784:Cholesterol