Association between alpha-1-antitrypsin types and the common cold.
Associations have been found between self-reported cold symptoms and Pi type in 84 pairs of identical twins. The risk of cold symptoms relative to MM phenotypes was 1.2 times greater in MS and 2.5 times greater in MZ individuals. Up to 9% of variance in cold symptoms could be attributed to Pi type, representing at least 20% of the total genetical variance.
D003139:Common Cold / Q000201:enzymology* / Q000235:genetics / Q000503:physiopathology; D005260:Female; D006801:Humans; D011247:Pregnancy; D014430:Twins, Monozygotic; D000515:alpha 1-Antitrypsin / Q000235:genetics*
D000515:alpha 1-Antitrypsin