A follow-up of the "low dose suppressible" hypercortisolism.
Five subjects with elevated excretion of urinary free cortisol but normal suppressibility to 2 mg dexamethasone test (i.e. with a "low dose suppressible" hypercortisolism) were followed over a period of one to three years. Two of them progressed into a typical pituitary-dependent Cushing's syndrome, whereas in three subjects a spontaneous regression of hypercortisolism was ascertained. A "low dose suppressible" hypercortisolism could therefore denote an early stage of Cushing's syndrome.
D000308:Adrenocortical Hyperfunction / Q000175:diagnosis* / Q000652:urine; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000652:urine; D003907:Dexamethasone / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000652:urine; D008297:Male; D013997:Time Factors
D003907:Dexamethasone; D006854:Hydrocortisone