Langerhans cells increase in the dermal lesions of adult T cell leukaemia in Japan.
In cases of adult T cell leukaemia neoplastic T cell infiltration in the skin was accompanied by an increase in Langerhans cells. This is in keeping with the view that Langerhans cells may induce antigen-specific and allogenic T cell activation.
D000328:Adult; D002452:Cell Count; D006801:Humans; D007801:Langerhans Cells / Q000648:ultrastructure*; D007938:Leukemia / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012867:Skin / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000648:ultrastructure*; D013601:T-Lymphocytes