Theoretical analysis of adenosine release from cardiac tissue as influenced by transport inhibitors.
The release of adenosine from cardiac tissue was simulated by use of a model equation which consists of a saturable transfer term for both unidirectional influx and efflux, representing a symmetrical facilitated diffusion mechanism. This proposed model can account for positive and negative changes in adenosine release from cardiac tissue brought about by competitive transport inhibitors.
D000241:Adenosine / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D001696:Biomechanical Phenomena; D008954:Models, Biological; D009206:Myocardium / Q000378:metabolism*
D000241:Adenosine