Production of 2'-deoxycoformycin by the fungus Emericella nidulans and its inhibitory effect on adenosine deaminase.
Isolation and characterization of 2'-deoxycoformycin from the culture filtrate of the fungus Emericella nidulance is described. Its inhibitory effect on adenosine deaminase (ADA, adenosine aminohydrolase, EC 3.5.4.4) is also described.
D058892:Adenosine Deaminase Inhibitors; D003070:Coformycin / Q000031:analogs & derivatives / Q000302:isolation & purification*; D005658:Fungi / Q000032:analysis*; D009700:Nucleoside Deaminases / Q000037:antagonists & inhibitors*; D015649:Pentostatin; D012263:Ribonucleosides / Q000302:isolation & purification*; D012988:Soil Microbiology
D058892:Adenosine Deaminase Inhibitors; D012263:Ribonucleosides; D003070:Coformycin; D015649:Pentostatin; D009700:Nucleoside Deaminases