title: [Extramedullary hemopoiesis in the mammary gland of neonates and young infants].
abstract: In a group of neonates and sucklings the development and extent of mammary haemopoiesis were studied as compared to the liver, axillary and mesogastric skin. Haemopoiesis was lacking in babies weighting round 1000 g at birth in the mammary epithelial anlage. Not until the lumina of glandular tubuli with encircling connective tissue developed, myelopoiesis and lymphopoiesis occurred associated with plasmacytes and mast cells as usual; erythropoiesis and megakaryocytes were found constantly as late as in babies  weighing over 1500 g at birth. The extent of haemopoiesis was related to increasing birth weight being the biggest in babies over 2000 g. The development of mammary haemopoiesis was opposite to liver and skin haemopoiesis; Mammary haemopoiesis decreased after birth and erythropoiesis was completely lacking at the end of neonatal period; small groups of myelopoiesis and lymphopoiesis with single megakaryocytes mostly remained as late as in early suckling period. There exists a positive influence of some diseases (e. g. asphyxia. inflammation, cyanotic congenital heart disease) on the persistence and extent of mammary haemopoiesis.
mesh_terms: D001940:Breast / Q000166:cytology*; D005260:Female; D006410:Hematopoiesis; D006413:Hematopoietic System / Q000166:cytology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male
vernacular_title: Extramedulární hemopoéza v mlécné zláze novorozenců a malých kojenců.