[Cellular and humoral immunological characteristics of chronic pyelonephritis].
The following indices were studied in 21 patients with chronic pyelonephritis: T-lymphocytes - early and late, their TG and TM subpopulations; B-lymphocytes: complement-receptor, antibody (hemolysin) synthesizing, carring surface immunoglobulins (sIg+) and cytoplasmatic immunoglobulins (cIg+); immunoblasts in peripheral blood; serum level of immunoglobulins and of C3 - fraction of complement. The authors established a tendency to increase of early T-lymphocytes and their TG - subpopulations in the patients. TM - subpopulations were considerably lower, as compared with those of the healthy subjects. The complement - receptor and immunoglobulin-containing B cella in the patients with chronic pyelonephritis were increased as compared with the same in healthy subjects. Only IgM level in serum of the patients studied was higher than in the healthy subjects from the humoral factors of immune reactivity. Chronic pyelonephritis, was concluded, by the authors, to participate in the cellular-humoral immune mechanisms with a predominating activation of B-populations and IgM synthesis.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D002417:Cattle; D002908:Chronic Disease; D003176:Complement C3 / Q000032:analysis; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008213:Lymphocyte Activation; D008297:Male; D011704:Pyelonephritis / Q000209:etiology / Q000276:immunology*; D011817:Rabbits; D013601:T-Lymphocytes / Q000276:immunology
D000906:Antibodies; D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Kletŭchno-khumoralna imunologichna kharakteristika na khronichniia pielonefrit.