[Relevant prognostic results in stomach cancer (analysis of variance and discriminance with clinical, morphologic and immunologic features)].
In 47 patients with an endoscopic-bioptic reliable gastric cancer two prognostic groups (good/poor) were set up by the help of clinical TNM-determination (gastroscopy, laparoscopy, operation), histology (bioptate and resectate) and long-term observation. In order to determine their prognostic significance 37 clinical, morphological and immunological parameters were recorded and analysed by the help of a multivariate analysis of variance and discriminance. The TNM-stage, erythrocyte sedimentation rate, the acid mucopolysaccharides in the tumour, circulating, complement binding immuncomplexes, B-cells, IgM, C3 and C4, IgE, gastritic degree and the infiltration of the tumour by neutrophile granulocytes and lymphocytes prove to be prognostic-discriminatoric significant. The parameters allowed a retrogradually-mathematically reliable classification of the patients into one of the both prognostic groups. The remaining features (age, sex, duration of the case history, Rohrer-index, tumour superficial spread, histological differentiation, neutral mucopolysaccharides, gastric activity, plasma cells and macrophages as stroma cells, IgG, IgA, auto-antibodies, dysproteinaemies, PEG-precipitate, T-cells, LAI-test, haemoglobin, total leucocyte count and total protein) prove to be redundant, i.e. they are unnecessary for calculation of the prognosis.
D000704:Analysis of Variance; D000936:Antigen-Antibody Complex / Q000032:analysis; D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D011379:Prognosis; D013223:Statistics as Topic; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
Prognoserelevante Befunde beim Magenkarzinom (Varianz- und diskriminanzanalytische Untersuchungen mit klinischen, morphologischen und immunologischen Merkmalen).