Susceptibility of Gardnerella vaginalis to cephradine.
The activity of cephradine and the influence of pH on its activity against 70 Gardnerella vaginalis strains were determined. Serial dilutions of cephradine (0.062 to 256 micrograms/ml) were incorporated into Dunkelberg agar, inoculated with a Steers replicator, incubated in 5% CO2 for 48 h, and examined. The minimal inhibitory concentrations for 90% of the isolates were 16 and 8.0 micrograms/ml at pH 7.0 to 6.0 and 5.5, respectively.
D002511:Cephalosporins / Q000494:pharmacology*; D002515:Cephradine / Q000494:pharmacology*; D003470:Culture Media; D006194:Gardnerella vaginalis / Q000187:drug effects*; D006190:Haemophilus / Q000187:drug effects*; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests
D002511:Cephalosporins; D003470:Culture Media; D002515:Cephradine