[Study of angiotensin II].
Radioisotopic competition of angiotensin II (A II) together with the use of structural analogues of this peptide are the two main methods of investigating the physiopathology of this hormone. Of great theoretical interest, the results of radioimmunological assay of plasma A II should be interpreted with caution because of the methodological difficulties related to its measurement and to the metabolic situation of A II. The values of the plasma A II alone do not provide additional information compared to PRA and are not representative of the pressor and biological effects of the hormone. The inhibitors of A II, although they too have a certain agonist activity, represent a method of precise investigation of the peripheral role of the hormone.
D000804:Angiotensin II / Q000031:analogs & derivatives / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism / Q000503:physiopathology; D011863:Radioimmunoassay; D012084:Renin-Angiotensin System
D000804:Angiotensin II
Exploration de l'angiotensine II.