Identification of Leb antigens in meconium of a phenotypically a Le(a+ b-) non-secretor individual.
Blood group active fucolipids of human meconium have been shown to correlate to the ABH and Lewis blood groups and to the secretor status of the corresponding children. Using a monoclonal anti-Leb antibody and an antibody to chromatogram binding assay the presence of Leb antigens in meconium of a phenotypically A Le(a+ b-) non-secretor individual is here demonstrated. Phenotype was determined on cord blood and saliva obtained 2 years after birth.
D000911:Antibodies, Monoclonal / Q000302:isolation & purification; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000302:isolation & purification*; D007983:Lewis Blood Group Antigens / Q000235:genetics / Q000276:immunology*; D008470:Meconium / Q000276:immunology / Q000378:metabolism*; D010641:Phenotype
D000911:Antibodies, Monoclonal; D007519:Isoantigens; D007983:Lewis Blood Group Antigens