[Analysis of the mechanism of the hypothermic action of neurotropic drugs].
Hypothermic action of neurotropic drugs (Oxotremorine, Nicotine, Isoprenaline, Seduxene) is evaluated by means of suppression of shivering thermogenesis. The action is accounted for by their influence of the brain stem level of the postural muscular tension regulation rather than by selective action of these drugs on the hypothalamic thermoregulatory centre.
D000818:Animals; D002415:Cats; D003975:Diazepam / Q000494:pharmacology; D007545:Isoproterenol / Q000494:pharmacology; D009420:Nervous System / Q000187:drug effects*; D009538:Nicotine / Q000494:pharmacology; D010095:Oxotremorine / Q000494:pharmacology; D010852:Picrotoxin / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D012601:Scopolamine / Q000494:pharmacology; D012768:Shivering / Q000187:drug effects*
D003975:Diazepam; D007545:Isoproterenol; D009538:Nicotine; D010095:Oxotremorine; D010852:Picrotoxin; D011433:Propranolol; D012601:Scopolamine
Analiz mekhanizma gipotermicheskogo deĭstviia neĭrotropnykh sredstv.