Simultaneous treatment of Raynaud's phenomenon and orthostatic hypotension.
Treatment of a 55-year-old woman with Raynaud's phenomenon and orthostatic hypotension secondary to lumbar sympathectomy performed for Raynaud's phenomenon is described. Indomethacin increased the blood pressure but caused severe gastrointestinal bleeding. It was possible to treat the symptoms of Raynaud's phenomenon with drugs generally used to treat hypertension without causing an undue decrease in blood pressure and, at the same time, to combat orthostatic hypotension with drugs to increase blood pressure.
D004359:Drug Therapy, Combination; D004809:Ephedrine / Q000008:administration & dosage*; D005260:Female; D005438:Fludrocortisone / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D006830:Hydralazine / Q000008:administration & dosage*; D007024:Hypotension, Orthostatic / Q000188:drug therapy* / Q000209:etiology; D008774:Methylphenidate / Q000008:administration & dosage; D008875:Middle Aged; D008914:Minoxidil / Q000008:administration & dosage; D011928:Raynaud Disease / Q000150:complications / Q000188:drug therapy*; D013562:Sympathectomy / Q000009:adverse effects; D014700:Verapamil / Q000008:administration & dosage
D008774:Methylphenidate; D006830:Hydralazine; D008914:Minoxidil; D014700:Verapamil; D004809:Ephedrine; D005438:Fludrocortisone