Posterior polymorphous corneal dystrophy of Schlichting. A clinical study on four families.
Posterior polymorphous corneal dystrophy of Schlichting was studied in 4 families. Nine persons were found with the typical lesions. Two families suggested a dominant mode of inheritance, in one of these with a penetrance less than 100%. There were 2 sporadic cases. No corneal oedema was present, and the central corneal thickness showed normal values, which means that the corneal endothelium in this dystrophy is able to maintain a normal hydrated cornea.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis / Q000235:genetics*; D005123:Eye / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009887:Ophthalmoscopy; D010375:Pedigree; D014792:Visual Acuity; D014794:Visual Fields