Relation between mucous cells and lymphoid tissue in rat intrapulmonary airways.
The distribution of mucous cells in rat intrapulmonary airways was investigated by conventional light microscopic technique. A striking association was found between differentiation of epithelial mucous cells and accumulation of lymphoid tissue in the lamina propria of bronchioli. Nodular accumulations of lymphoid tissue, covered by a lymphoepithelium, as well as differentiation of mucous cells, increased with age. This normal development was accelerated in rats exposed to aerosolized ovalbumin.
D000375:Aging; D000818:Animals; D001980:Bronchi / Q000276:immunology / Q000473:pathology*; D002454:Cell Differentiation; D007249:Inflammation / Q000276:immunology / Q000473:pathology; D008221:Lymphoid Tissue / Q000276:immunology / Q000473:pathology*; D009092:Mucous Membrane / Q000276:immunology / Q000473:pathology; D010047:Ovalbumin / Q000008:administration & dosage / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains
D010047:Ovalbumin