Eukaryotic genome: model considerations.
The paper presents a new model of chromosome structure based on the assumption that multiple circular subunits of DNA exist. The essential difference with previously described models is the circular DNA unit forms a central chromosome axis. Chromosome configurations during various phases of the cell cycle depend on the various conformations of this central integrating unit. The described model can be generalized for all haploid set of eukaryotic nucleus. Some aspects of the chromosome structure and their functions have been discussed.
D000818:Animals; D002875:Chromosomes; D004261:DNA Replication; D004270:DNA, Circular; D006238:Haploidy; D008938:Mitosis; D008957:Models, Genetic; D011995:Recombination, Genetic; D014178:Translocation, Genetic
D004270:DNA, Circular