title: [Spontaneous radial segmentation of cell nuclei: morphologic marker of T-cell neoplasms?].
abstract: Radial segmentation (RS) of leukocyte nuclei has been observed, for example, in leukemias (Rieder cells). In 6 of 8 patients with T-ALL, RS of neoplastic cells was found in the peripheral blood, whereas in 14 patients with non-T-ALL no RS cells were present. RS may be a morphologic marker for certain T-cell neoplasms, and with regard to ultrastructure it seems to be identical to heat-induced RS of non-neoplastic cells.
mesh_terms: D002467:Cell Nucleus / Q000473:pathology* / Q000648:ultrastructure; D002471:Cell Transformation, Neoplastic / Q000473:pathology* / Q000648:ultrastructure; D006358:Hot Temperature; D006801:Humans; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology*
vernacular_title: Spontane Radialsegmentierung von Zellkernen: ein morphologischer Marker von T-Zell-Neoplasien?