Cystographic contrast media: clinical and experimental studies.
Cysto-Conray II 17.2% (81 mg l/ml), diluted Cysto-Conray 10% (47 mg l/ml), and Hypaque-Cysto 10% (47 mg l/ml) produced no histologic effects on rat bladders. Simulated ureters in water phantoms were well shown with lower concentrations of cystographic solutions including those of 5% (24 mg l/ml). In clinical studies there was little difference between Cysto-Conray II 17.2% and Hypaque-Cysto 10% for delineating refluxing ureters, bladder margins, and the urethra. Intraluminal filling defects in dog bladders were demonstrated best with cystographic concentrations of less than 10% (47 mg l/ml).
D000818:Animals; D003287:Contrast Media / Q000633:toxicity*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008297:Male; D008961:Models, Structural; D011859:Radiography; D051381:Rats; D011919:Rats, Inbred Strains; D014513:Ureter / Q000000981:diagnostic imaging; D014521:Urethra / Q000000981:diagnostic imaging; D001743:Urinary Bladder / Q000000981:diagnostic imaging* / Q000187:drug effects
D003287:Contrast Media