title: Essential fatty acid deficiency: a suggestion concerning experimental design.
abstract: In experiments on essential fatty acid deficiency, various strategems have been used to balance the deficient and control groups for all nutrients except essential fatty acids. We suggest the use of a single fat-free diet for both groups, with essential fatty acids administered parenterally to the control (nondeficient) group once each week.
mesh_terms: D000818:Animals; D003872:Dermatitis / Q000209:etiology; D004041:Dietary Fats / Q000008:administration & dosage; D004655:Emulsions; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage; D005228:Fatty Acids, Essential / Q000172:deficiency*; D005526:Food, Formulated; D054709:Lecithins; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D012107:Research Design; D012450:Safflower Oil; D013024:Soybean Oil
chemical_list: D004041:Dietary Fats; D004655:Emulsions; D005217:Fat Emulsions, Intravenous; D005228:Fatty Acids, Essential; D054709:Lecithins; C031435:safflower oil, soybean oil, lecithin emulsion; D013024:Soybean Oil; D012450:Safflower Oil