title: Aortic valve replacement in childhood: evaluation of left ventricular function by electrocardiography, echocardiography and graded exercise testing.
abstract: Preoperative and postoperative left ventricular (LV) performance was evaluated noninvasively in 15 children who survived aortic valve replacement (AVR). The noninvasive evaluation included electrocardiography, M-mode echocardiography, and graded exercise testing. Clinically, there was dramatic improvement postoperatively: All but 2 patients were asymptomatic. No conduction defects or arrhythmias were detected preoperatively; however, in the late postoperative period there was a variety of intraventricular conduction abnormalities, myocardial infarctions, and ventricular or supraventricular arrhythmias. On M-mode echocardiography, children with aortic stenosis continued to have increased LV mass postoperatively. Shortening fraction and left-sided systolic time intervals returned to normal. The children with aortic regurgitation also had persistently abnormal LV mass on echocardiography postoperatively. Exercise data indicated no improvement in working capacity after AVR. Also, 9 children (63%) continued to have ST-segment depression with maximal exercise. These data indicate that AVR does not result in a return to normal of myocardial performance in children with severe aortic valve disease.
mesh_terms: D000293:Adolescent; D001021:Aortic Valve; D001022:Aortic Valve Insufficiency / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000503:physiopathology / Q000601:surgery*; D001705:Bioprosthesis; D002648:Child; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006350:Heart Valve Prosthesis; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D009200:Myocardial Contraction; D011183:Postoperative Complications / Q000175:diagnosis; D013997:Time Factors