[Amino acyl tRNA synthetase complexes in rabbit liver in experimental myocardial infarction].
The composition of high-molecular complexes of aminoacyl-tRNA-synthetases (ARSase) from the rabbit liver was studied on the first day after reproduction of the experimental myocardium infarction. The studies revealed an increase in the glutamyl-, leucyl-, lysyl- and a decrease in the glycyl- and seryl-tRNA-synthetase activities and redistribution of the last two enzymes from the composition of the complexes into a lower-molecular fraction of postribosomal supernatant fluid. Under the experimental myocardium infarction the complexes reveal a significant decrease in the content of phospholipids and variations in the electrophoretic mobility of protein fractions. An assumption is advanced that a disturbed protein biosynthesis in the liver resulted from the experimental myocardium infarction causes changes in the structural organization of the ARSase complexes.
D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism*; D000818:Animals; D002852:Chromatography, Ion Exchange; D008099:Liver / Q000201:enzymology*; D008970:Molecular Weight; D009203:Myocardial Infarction / Q000201:enzymology*; D011817:Rabbits; D013997:Time Factors
D000604:Amino Acyl-tRNA Synthetases
Izuchenie kompleksov aminoatsil-tRNK-sintetaz pecheni krolika pri éksperimental'nom infarkte miokarda.