title: Characterization of the inflammatory infiltrate in lupus erythematosus lesions using monoclonal antibodies.
abstract: The inflammatory infiltrates of cutaneous lupus lesions from 14 patients with benign cutaneous, subacute cutaneous or systemic lupus erythematosus were examined for T and B lymphocytes, macrophages and Ia positive cells using monoclonal antibodies and a peroxidase antiperoxidase technique. T cells and Ia positive cells were present in abundance followed by B cells then macrophages. Approximately equal numbers of helper/inducer T cells (OKT4, Leu3a) and suppressor/cytotoxic T cells (OKT8, Leu-2a) were present in the inflammatory infiltrate.
mesh_terms: D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000276:immunology / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000276:immunology* / Q000473:pathology; D008264:Macrophages / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000949:Histocompatibility Antigens Class II