title: Fetal scalp blood lactate as an indicator of intrapartum hypoxia.
abstract: Fetal scalp blood lactate was measured during labour by a simple, rapid method and its value as an indicator of fetal intrauterine hypoxia was assessed and compared with that of pH measurement. The normal ranges of lactate concentration and of pH values were calculated. Significantly higher concentrations of lactate and lower pH values were found in samples of scalp blood taken close to delivery from babies with Apgar scores of less than or equal to 6 at 1 min compared with those from healthy babies with Apgar scores of greater than or equal to 7 at 1 min. A similarly significant difference was observed between the cord blood lactate and pH values of these two groups of babies. Ominous fetal heart rate patterns were associated with higher lactate concentrations and lower pH values in fetal scalp blood than were normal fetal heart rate patterns. The measurement of fetal scalp blood lactate or pH, or continuous electronic fetal heart rate monitoring were equally good at predicting the condition of the infant at birth.
mesh_terms: D001034:Apgar Score; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005318:Fetal Heart / Q000503:physiopathology; D005311:Fetal Hypoxia / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007743:Labor, Obstetric; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D011247:Pregnancy; D012535:Scalp / Q000098:blood supply* / Q000196:embryology
chemical_list: D007773:Lactates; D019344:Lactic Acid