title: [Morphogenesis of early pre-lipid stages of atherosclerosis].
abstract: Investigation of early changes in the aortal wall (focal edema of the intima, rhythmic structures, and primary fibrous plaques) in children and young subjects showed the possibility of nonlipidogenic mode of the development of atherosclerotic plaques. The data suggest that an important role in the genesis of atherosclerotic changes in man is played by local alterations of the arterial wall not associated with disorders in the general lipid metabolism. The local damage of the endothelial lining of the arteries in these sites may be very important in their genesis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001012:Aorta, Abdominal / Q000378:metabolism / Q000473:pathology; D001013:Aorta, Thoracic / Q000378:metabolism / Q000473:pathology; D001018:Aortic Diseases / Q000209:etiology / Q000473:pathology*; D001161:Arteriosclerosis / Q000209:etiology / Q000473:pathology*; D002648:Child; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000378:metabolism / Q000473:pathology; D011817:Rabbits; D013997:Time Factors
chemical_list: D005340:Fibrinogen
vernacular_title: Morfogenez rannikh dolipidnykh stadiĭ ateroskleroza.