[Location of acetylcholinesterase in axotomized ciliary ganglia].
In the present note we have investigated the cytochemical localization of acetylcholinesterase (AChE) in the chick ciliary ganglion (CG) after post-ganglionic axotomy obtained by ablation of the eyeball. Preliminary results show at quite early stages after axotomy a remarkable reduction of cytoplasmic AChE, the residual one being localized in the rough endoplasmic reticulum. On the contrary synaptic areas, in particular those concerning the calyciform synapses, still show a marked AchE activity, similarly to what observed in physiological conditions. The decrease of cytoplasmic AChe in axotomized CG does suggest the possibility that such AChE undergoes to a topographical rearrangement moving towards the synaptic areas of ganglionic neurons.
D000110:Acetylcholinesterase / Q000032:analysis*; D000818:Animals; D001369:Axons / Q000502:physiology; D005726:Ganglia, Parasympathetic / Q000201:enzymology*
D000110:Acetylcholinesterase
Localizzazione dell'acetilcolinesterasi nel ganglio ciliare assotomizzato.