Continuous intravenous administration of drugs.
Continuous intravenous administration of drugs may be a problem in clinical practice; for several reasons patients do not always receive the dose of drug intended for them. Problems of parenteral fluid composition are related to the solvent, dilution and drug interactions. Physical factors influencing drug stability are light and adsorption onto perfusion sets. Examples are reported for each problem. A practical solution, based on personal experimentation, is proposed for diazepam and nitroglycerin administration.
D000327:Adsorption; D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D004355:Drug Stability; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007263:Infusions, Parenteral; D008027:Light; D012996:Solutions; D012997:Solvents
D012996:Solutions; D012997:Solvents