[Sero-epidemiologic studies of acute hepatitis A in Umbria: behavior of IgM anti-HAV antibodies].
The diagnosis of acute Hepatitis A is made when antibodies anti-HAV, of the IgM class, are detected in the blood. The Authors have examined with RIA test (HAVAB-M, Abbott) 298 samples of serum from patients with acute non B hepatitis, non drug abusers, also they had not received blood transfusions; as control they examined 41 sera from patients with hepatitis B, 29 sera from patients with non B hepatitis and drug addiction, 25 sera from patients with transfusional non B hepatitis and 37 sera from healthy persons. From the first group (298 patients) 47% were positive for anti-HAV antibodies IgM class; the greatest incidence of positivity (80%) was detected in the class age 0-10 years. In the control groups only in one serum positivity was evidenced and the patient was 22 years old, drug addicted with non B acute hepatitis and with previous episodes of acute hepatitis.
D000293:Adolescent; D000328:Adult; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D002648:Child; D006506:Hepatitis A / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M; D007558:Italy; D008875:Middle Aged
D000888:Antibodies, Anti-Idiotypic; D007075:Immunoglobulin M
Ricerche sieroepidemiologiche sull'epatite acuta A in Umbria: comportamento degli anticorpi IgM anti-HAV.