title: Susceptibility of the expression of parallel tubular structures in lymphocytes to the exposure to ammonium chloride buffer.
abstract: In isolation procedures for lymphocytes, isotonic ammonium chloride buffers are frequently used to lyse erythrocytes. In addition to evidence for an effect on lymphocyte function we now report a morphological alteration after treatment of lymphocytes with ammonium chloride buffer. Expression of parallel tubular structures was lost and only amorphous, electron-dense granules could be observed.
mesh_terms: D000643:Ammonium Chloride / Q000494:pharmacology*; D002021:Buffers; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood; D008214:Lymphocytes / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D002021:Buffers; D000643:Ammonium Chloride