title: Some statistical data, diagnosis, and staging of cutaneous B-cell lymphomas.
abstract: Cutaneous B-cell lymphomas represent a considerable number of skin lymphomas (about one-third) primarily showing skin manifestation without any extranodal involvement detectable using routine and special staging procedures. Differentiation from cutaneous T-cell lymphomas can be achieved clinically; histologically, due to the distinct growth pattern in the skin; and by immuno- or enzymophenotyping of the proliferating cells. Further differentiation of subtypes of cutaneous B-cell lymphomas is based primarily on cytomorphologic phenotyping of the cells. Classification of B-cell lymphomas with "primary" cutaneous manifestation according to the TNM system discloses a more adequate basis for prognostic and therapeutic considerations than the Ann Arbor classification for nodal lymphomas.
mesh_terms: D001402:B-Lymphocytes; D006801:Humans; D008223:Lymphoma / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D009367:Neoplasm Staging; D010641:Phenotype; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D013601:T-Lymphocytes