Growth inhibition of an MC-induced mouse sarcoma by TCGF (IL 2)-containing preparations. Preliminary report.
Supernatants from Con A-stimulated rat spleen cell cultures containing T cell growth factor inhibited growth of a transplantable 3-methylcholanthrene-induced sarcoma in syngeneic mice. The tumour-inhibitory effects were dependent on the concentration of T cell growth factor and repeated injections of the supernatants.
D000818:Animals; D002460:Cell Line; D007167:Immunotherapy; D007376:Interleukin-2 / Q000627:therapeutic use*; D008214:Lymphocytes / Q000276:immunology; D008748:Methylcholanthrene; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000628:therapy*; D013154:Spleen / Q000276:immunology
D007376:Interleukin-2; D008748:Methylcholanthrene