[The role of glycosphingolipids in the immune process].
The paper deals with the role of glycosphingolipids as antigens and receptors of immunocompetent cells as well as modulators of the immune response. Glycosphingolipids are shown to be markers of different immunocompetent cells, serve as receptors of the factor inhibiting the migration of macrophages on their surface, inhibit or stimulate the lymphocyte differentiation, inhibit the cytotoxic-action of natural killers. A possible effect of glycosphingolipids on the immune response during tumour growth is discussed.
D000818:Animals; D002462:Cell Membrane / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D006028:Glycosphingolipids / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D011971:Receptors, Immunologic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D006028:Glycosphingolipids; D011971:Receptors, Immunologic
Rol' glikosfingolipidov v immunologicheskom protsesse.