title: Finite element analysis of current pathways with implanted electrodes.
abstract: A technique for numerical solution to complex electric field distribution problems has been devised. The specific application for which it was developed is the analysis of current density and isopotential line spacing from implanted neurostimulation electrodes. Three configurations of cerebellar stimulation electrodes in clinical use were studied for current spread to regions distant from the cerebellum using a planar model of the human head, neck, and upper torso in mid-saggital section. It was found that an array of cathodes on the superior cerebellar surface and an array of anodes on the inferior cerebellar surface causes significant current spread to the brainstem, a prediction confirmed by clinical observation in patients with previously implanted electrodes of this configuration. Results modelling other electrode configurations are also presented, along with a study of the effects of possible inaccuracies in available impedance data for neural tissue.
mesh_terms: D001927:Brain Diseases / Q000628:therapy; D001933:Brain Stem / Q000502:physiology; D002531:Cerebellum / Q000502:physiology*; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D004867:Equipment Design; D006801:Humans; D008433:Mathematics; D001523:Mental Disorders / Q000628:therapy; D008961:Models, Structural