Proliferation of astroglia and oligodendroglia in response to human T cell-derived factors.
Human T lymphocytes transformed by human T cell leukemia-lymphoma viruses or activated by lectins were found to produce stimulating factors that promoted both proliferation and maturation of oligodendroglial and astroglial cells in vitro.
D000328:Adult; D000818:Animals; D001253:Astrocytes / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line; D006133:Growth Substances / Q000494:pharmacology*; D006801:Humans; D008213:Lymphocyte Activation; D008222:Lymphokines / Q000494:pharmacology; D009457:Neuroglia / Q000187:drug effects*; D009836:Oligodendroglia / Q000187:drug effects*; D051381:Rats; D011961:Receptors, Fc / Q000378:metabolism; D013601:T-Lymphocytes / Q000502:physiology*
D006133:Growth Substances; D008222:Lymphokines; D011961:Receptors, Fc