[Fumarate reductase in the mitochondria of the trematode Calicophoron ijimai].
The presence of active fumarate reductase system in mitochondria of the trematode Calicophoron ijimai was shown. Fumarate reductase activities in different collections of C. ijimai vary considerably. Maximum activity accounts for 47.7 +/- 1.0 nM/min/mg protein whereas minimum--for 15.1 +/- 0.1. Some properties of the enzyme were studied. The effect of thiabendazole, bitionol, oxinid and preparations of G-1026 and G-937 on the fumarate reductase activity was investigated. G-1026, G-937 preparations and bitionol have the strongest inhibitory effect on the enzyme. Thiabendazole inhibited but little the fumarate reductase reaction in C. ijimai. The enzyme activity was not affected by oxinid.
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria / Q000201:enzymology*; D010084:Oxidation-Reduction; D013385:Succinate Dehydrogenase / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014200:Trematoda / Q000201:enzymology*; D014201:Trematode Infections / Q000469:parasitology / Q000662:veterinary
D000871:Anthelmintics; D013385:Succinate Dehydrogenase
Fumaratreduktaza v mitokhondriiakh trematody Calicophoron ijimai.