title: Histochemical labeling of drug receptors in schistosomes: quantitation using computer image analysis techniques.
abstract: Computer image analysis techniques were used to quantitate the histochemical labeling of schistosomes with dimethylaminonaphthalene-5-sulfonaminoethyl methylamine hydrochloride (DDNS), a fluorescent analog of acetylcholine (ACh). Dose-response curves, consistent with previous experiments, were obtained for DDNS, and for blockage of DDNS labeling, by trifluoperazine and mecamylamine.
mesh_terms: D000818:Animals; D003201:Computers; D003619:Dansyl Compounds; D005456:Fluorescent Dyes; D006651:Histocytochemistry; D007089:Image Enhancement / Q000379:methods; D008856:Microscopy, Fluorescence; D011955:Receptors, Drug / Q000032:analysis*; D012547:Schistosoma / Q000378:metabolism*
chemical_list: D003619:Dansyl Compounds; D005456:Fluorescent Dyes; D011955:Receptors, Drug; C039018:dimethylaminonaphthalene-5-sulfonaminoethylmethylamine