title: [Preservation of the enzyme activity of horseradish peroxidase administered into the gastrointestinal tract of adult dogs and rats].
abstract: Enzymatic activity of horse radish peroxidase administered to the gastrointestinal tract of adult dogs and rats was assessed. It was discovered that in adult dogs, 30% of the protein reached the distal parts of the small intestine in a non-splitted form. As early as two hours after administering horse radish peroxidase over 15% of active enzyme was detectable in the gastrointestinal tract of adult rats. 0.5% of non-splitted enzyme was found in the rat large intestine.
mesh_terms: D000818:Animals; D004064:Digestive System / Q000201:enzymology*; D004285:Dogs; D006735:Horseradish Peroxidase / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D010544:Peroxidases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012710:Serum Albumin, Bovine / Q000008:administration & dosage / Q000378:metabolism; D013997:Time Factors
chemical_list: D012710:Serum Albumin, Bovine; D006735:Horseradish Peroxidase; D010544:Peroxidases
vernacular_title: Sokhranenie fermentativnoĭ aktivnosti peroksidazy iz khrena, vvedennoĭ v zheludochno-kishechnyĭ trakt vzroslykh sobak i krys.