title: Genetic variants of serum alpha-1-antitrypsin (Pi types) in a Breton population, the Bigoudens.
abstract: Pi typing was carried out by high resolution isoelectric focusing in 397 Bigoudens and in 100 non-Bigouden Bretons. Gene frequencies were computed by the gene counting method. No difference between the two groups could be demonstrated, neither was there a deviation from the expected Hardy-Weinberg distribution nor a heterogeneity between the Bigouden villages. The results were significantly different (p less than 0.02) from those reported in Normans.
mesh_terms: D005006:Ethnicity; D005260:Female; D005602:France; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D010641:Phenotype; D000515:alpha 1-Antitrypsin / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
chemical_list: D000515:alpha 1-Antitrypsin