title: [Assessment of blood platelet status in acute myocardial infarction].
abstract: Circulating platelet morphology (using scanning electron microscopy), platelet adhesion and flattening on silicone slides (interference contrast microscopy), and spontaneous platelet aggregation were investigated. Platelet status was thus assessed in patients with acute myocardial infarction (AMI), chronic coronary disease (CCD) and normal subjects (controls). In AMI patients, the majority of circulating platelets were inactivated: 70% and more were of smooth discoid shape, a finding similar to that of the controls. On the contrary, platelet flattening, adhesion and spontaneous aggregation were changed in AMI patients, and also, though on a smaller scale, in CCD patients. Changes in platelet flattening ability were most pronounced, the latter parameter being sharply increased in 73% of AMI patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000473:pathology / Q000502:physiology / Q000503:physiopathology*; D003327:Coronary Disease / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation; D013923:Thromboembolism / Q000209:etiology
vernacular_title: Otsenka sostoianiia trombotsitov pri ostrom infarkte miokarda.