title: [Methodological problems of screening immunotropic agents].
abstract: The author analyzes the requirements for the models applied in the screening of immunotropic agents. Reviews the characteristics of the screening of such substances. Suggests a variant to be used in the system of screening the immunotropic drugs.
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000937:Antigen-Antibody Reactions / Q000187:drug effects; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004306:Dose-Response Relationship, Immunologic; D004353:Drug Evaluation, Preclinical / Q000379:methods; D007109:Immunity / Q000187:drug effects; D007111:Immunity, Cellular / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D008221:Lymphoid Tissue / Q000187:drug effects / Q000276:immunology; D012107:Research Design; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents
vernacular_title: O nekotorykh metodologicheskikh voprosakh skrininga immunotrpnykh sredstv.