[Muscle blood flow in healthy persons of different ages].
A study was made of the muscular blood flow at rest (MBFR) and in reactive hyperemia (MMBF--maximum muscular blood flow) in 170 healthy persons using a method of local clearance with 133Xe. The results of the study showed a regular decrease in the MBFR and MMBF level in aging, the decrease rates of MMBF considerably prevailing over those of MBFR. In the age interval between 18-96 MBFR lessens by 24%, MMBF more than twice. The age-associated time course of MMBF is of a more complicated nature as compared to that of MBRF and indicates a considerable reduction of the functional reserves of the tissue blood flow in the skeletal muscles of middle-aged and old persons. The above data make it possible to outline MBFR rough standard values: for young persons--2.5-5.0 ml/100 g/min., for older persons--1.5-3.5 ml/100 g/min. As normal MBFR fluctuations in healthy persons one can adopt a +/- 20% interval of respective MBRF mean values in each decade. MBF age-associated changes should be regarded in the diagnosis of obliterating lesions of lower limb vessels and other diseases accompanied by its decrease. Special emphasis should be placed on MMBF.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D001811:Blood Volume Determination; D005260:Female; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000098:blood supply* / Q000000981:diagnostic imaging; D005082:Physical Exertion; D011877:Radionuclide Imaging; D012016:Reference Values; D012039:Regional Blood Flow; D012146:Rest; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes
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