title: Aggressive basal cell epithelioma on sunlight-protected skin. Report of eight cases, one with pulmonary and bone metastases.
abstract: This report concerns a series of eight patients with large basal cell epitheliomas that occurred on sunlight-protected areas of the trunk. Histologically, the neoplasms exhibited highly "invasive" features and were complicated by recurrences. Five years after removal of one of the neoplasms by surgical excision, regional lymphatic metastasis occurred. This was followed by distant metastases to the lung and pelvic bone.
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D002280:Basal Cell Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*