Potentiation of the antibody induced platelet aggregation in vitro.
The combined addition of a heterologous anti-human C1q serum and an anti-IgG-L-chain (kappa) serum to only once washed human platelets potentiates their aggregation in vitro in comparison to the effect of the same antisera alone. The biological significance of this process is discussed.
D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D003166:Complement Activating Enzymes / Q000276:immunology; D015922:Complement C1q; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D066298:In Vitro Techniques; D010974:Platelet Aggregation
D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G; D015922:Complement C1q; D003166:Complement Activating Enzymes