[Correlation between the T, K and NK cell count and the IgE level in patients with atopy (pollinosis)].
In a homogenous group of patients with polyposis, IgE level was juxtaposed to the number of E-rosette-forming cells (E-RFC), K- and NK-cells. The effect of a parenterally introduced allergen (via an accelerated course hyposensibilization) was also determined upon those indices. The number of E-RFC was diminished in the patient group (53,1 +/- 3,3%) as compared with the results (67,2 +/- 2,1%) obtained from the control subjects, selected by the control method of couples. A dependence of a direct ratio was found between the number of E-RFC and IgE level in the patients. The number of K- and NK-cells in the patients did not significantly differ from their number in the control subjects; no relationship was found between the number of K-cells and the number of NK-cells, between those cells and IgE level or the number of E-RFC. Allergen-specific cells - kilers were present in the peripheral blood of the patients with polyposis. The course of specific hyposensibilization carried out was accompanied, in all patients by increased number of E-RFC (to 122 +/- 7% as compared with the initial level) and a reduction of the number of K-cells (to 36 +/- 5.4% as compared with the initial level). Both the changes in IgE level and the number of NK-cells were not of one type in all patients.
D000328:Adult; D000918:Antibody Specificity; D002908:Chronic Disease; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology* / Q000628:therapy; D007073:Immunoglobulin E / Q000032:analysis*; D007694:Killer Cells, Natural / Q000276:immunology*; D007958:Leukocyte Count; D008297:Male; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology* / Q000628:therapy; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D007073:Immunoglobulin E
Sŭotnoshenie mezhdu broia na T-, K-, NK-kletkite i nivoto na IgE u bolni s atopiia (polinoza).