title: Action of testosterone on some biochemical parameters related to the energy metabolism of the skeletal muscle.
abstract: The effect of intramuscular administration of testosterone propionate was studied on rat gastrocnemius muscle. Muscular glycolytic substrates and Krebs' cycle metabolites (glycogen, glucose, glucose-6-phosphate, pyruvate, lactate, citrate, alpha-ketoglutarate, succinate, malate), related aminoacids (glutamate, alanine, ammonia), energy store and mediators (creatine phosphate, ATP, ADP, AMP) and the energy charge potential were evaluated. The influence of the factors: testosterone dose, time course of treatment and sex of animals was investigated, no relevant changes being noticed.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects*; D005260:Female; D006019:Glycolysis / Q000187:drug effects; D008297:Male; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D012737:Sex Factors; D013739:Testosterone / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000596:Amino Acids; D013739:Testosterone