Radioresponse of peripheral blood and its modification by MPG (2-mercaptopropionylglycine) in mice IV total plasma protein.
Adult Swiss albino mice were irradiated with different doses of Co-60 gamma rays (2.5,5.0 and 10.0 Gy) in the presence or absence of the radioprotective drug MPG. It was found that the total plasma protein was at low ebb on day 5 and 7 in the 5 and 10 Gy exposure groups respectively, but no significant change was observed either in the drug protected or in the non-drug protected groups after 2.5 Gy exposure. A significant elevation in the plasma protein level was found at later intervals i. e. from day 5 on in the 5.0 and 10.0 Gy dose groups receiving MPG before irradiation in comparison to the corresponding non-drug protected group.
D000603:Amino Acids, Sulfur / Q000494:pharmacology*; D000818:Animals; D001769:Blood / Q000528:radiation effects*; D001798:Blood Proteins / Q000032:analysis*; D003037:Cobalt Radioisotopes; D051379:Mice; D011829:Radiation Dosage; D013997:Time Factors; D008625:Tiopronin / Q000494:pharmacology*
D000603:Amino Acids, Sulfur; D001798:Blood Proteins; D003037:Cobalt Radioisotopes; D008625:Tiopronin