Treatment of trichinosis with mebendazole.
Prolonged oral high-dose mebendazole therapy provided an effective anthelmintic regimen for trichinosis unresponsive to steroid therapy in one patient. Side effects were limited to a Herxheimer-like reaction. Serum mebendazole levels documented gastrointestinal absorption. Repeat muscle biopsies and fluorescein angiography substantiated objective improvement.
D000284:Administration, Oral; D001562:Benzimidazoles / Q000627:therapeutic use*; D004576:Electromyography; D005260:Female; D006801:Humans; D008463:Mebendazole / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D008875:Middle Aged; D009132:Muscles / Q000469:parasitology; D014234:Trichinella / Q000166:cytology; D014235:Trichinellosis / Q000188:drug therapy*
D001562:Benzimidazoles; D008463:Mebendazole