Ocular findings in Alport's syndrome.
6 cases of Alport's syndrome with ocular findings are presented and discussed. 4 cases had bilateral anterior lenticonus, one had retinal changes similar to the flecked retina syndrome and 1 case had posterior polymorphous corneal changes, a previously unreported finding. The varied ocular changes presented here all have in common a pathologic process involving the basement membrane or the specialized epithelium.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology; D005128:Eye Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D007905:Lens Diseases / Q000473:pathology; D008268:Macular Degeneration / Q000473:pathology; D008297:Male; D009394:Nephritis, Hereditary / Q000473:pathology*; D009887:Ophthalmoscopy; D012164:Retinal Diseases / Q000473:pathology; D014786:Vision Disorders / Q000473:pathology; D014792:Visual Acuity