title: Increase of lymphocytic H-Y antigen in female 21-hydroxylase deficiency.
abstract: H-Y antigen was found to be increased in lymphocytes from 10 female 21-hydroxylase deficiencies, suggesting a correlation between the degree of virilization of these patients and their H-Y + lymphocytes proportions. Furthermore, these findings demonstrate the ability of a 46,XX female subject to produce, in some circumstances, an excess of H-Y antigen.
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000276:immunology; D000328:Adult; D000818:Animals; D002648:Child; D012734:Disorders of Sex Development / Q000276:immunology; D005260:Female; D006182:H-Y Antigen / Q000032:analysis*; D006628:Hirsutism / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013250:Steroid Hydroxylases / Q000172:deficiency*
chemical_list: D006182:H-Y Antigen; D013250:Steroid Hydroxylases