Comparative study of piroxicam and ibuprofen in rheumatoid arthritis.
Piroxicam was compared with ibuprofen in a 8 weeks randomised open clinical trial in 31 patients (16 patients with piroxicam and 15 patients with ibuprofen) with rheumatoid arthritis. Piroxicam was given in a dosage of 20mg once daily and ibuprofen 400mg three times a day. Both drugs appeared to be equally effective and there were only few minor side effects in patients on either drug. The once daily administration gives piroxicam a clear practical advantage over ibuprofen.
D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010894:Piroxicam; D011897:Random Allocation; D013843:Thiazines / Q000009:adverse effects / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013843:Thiazines; D010894:Piroxicam; D007052:Ibuprofen