Effect of gonadectomy and adrenalectomy on steroid hormone content in rat submaxillary gland.
In male rats the adrenals appear to be a main source of progestagen in submaxillary glands, while in female rats the same is true for ovaries and adrenals. In both sexes certain amounts of progestagens were found in submaxillary glands up to 21 days after gonadectomy and adrenalectomy which might suggest that submaxillary glands possess the ability to synthesize these steroids. In contrast, however, almost negligible concentrations of androgens in submaxillary glands were observed in male rats beginning from 3 to 6 days after castration from which it may be concluded that no androgen producing ability is present in this tissue.
D000315:Adrenalectomy; D000728:Androgens / Q000378:metabolism*; D000818:Animals; D002369:Castration; D005260:Female; D008297:Male; D011372:Progestins / Q000097:blood / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013363:Submandibular Gland / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism
D000728:Androgens; D011372:Progestins