The incidence of anti-RANA in Mexican Mestizo populations with rheumatoid arthritis or other conditions.
The anti-RANA antibody was first described as a serologic characteristic of Caucasian patients with seropositive rheumatoid arthritis (RA). To determine whether there is uniformity among diverse racial groups in the finding of elevated titers of anti-RANA in RA, we studied a Mexican Mestizo population. We found that this population also has a high frequency of anti-RANA and indicates that high frequencies of anti-RANA in RA will probably be true for all populations. A previously unrecognized association between extraarticular manifestations and positive anti-RANA was suggested among RA patients. The possible significance of elevated anti-RANA titers in RA is discussed.
D000974:Antibodies, Antinuclear / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D008800:Mexico; D012217:Rheumatoid Factor / Q000032:analysis
D000974:Antibodies, Antinuclear; D012217:Rheumatoid Factor