Studies of residual alkali on intraocular lenses sterilized with NaOH.
We measured the effects of pH changes after water washings of polymethylmethacrylate (PMMA) intraocular lenses sterilized in 10% sodium hydroxide (NaOH). Whereas inserting the base-sterilized lens directly into the eye causes a large pH change in the local area of the implant, three separate washings of the NaOH-treated implant in 15 ml of water eliminates this change. No buffer is required.
D006801:Humans; D006863:Hydrogen-Ion Concentration; D007910:Lenses, Intraocular / Q000592:standards*; D008768:Methylmethacrylates / Q000592:standards; D012972:Sodium Hydroxide; D013242:Sterilization / Q000379:methods*
D008768:Methylmethacrylates; D012972:Sodium Hydroxide