New alpha-amylase inhibitor, trestatins. II. Structure determination of trestatins A, B and C.
The structures of trestatins A (C56H94N2O40), B (C37H63NO28) and C (C75H125N3O52), new basic oligosaccharides with potent inhibitory activity against various alpha-amylases, have been shown by spectroscopic and chemical methods to be 1, 2 and 3, respectively.
D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009844:Oligosaccharides; D009904:Optical Rotation; D013329:Structure-Activity Relationship; D014312:Trisaccharides / Q000494:pharmacology; D000516:alpha-Amylases / Q000037:antagonists & inhibitors*
D007202:Indicators and Reagents; D009844:Oligosaccharides; D014312:Trisaccharides; C038505:trestatin; D000516:alpha-Amylases