title: Genetics of insect hemolymph alpha-mannosidase in the silkworm, Bombyx mori.
abstract: The genetics of hemolymph alpha-mannosidase was investigated in the silkworm, Bombyx mori. By selecting individuals showing either high or low enzyme activities, homozygotes were separated, with activities varying about five-fold. No differences in the activities of beta-galactosidase and beta-N-acetylglucosaminidase were observed. Thus, it seems that high- and low-enzyme silkworms (High and Low Lines) share the same genetic background except for the gene concerning the activity of alpha-mannosidase. The synthesis of the enzyme is controlled by an autosomal allele. Furthermore, expression of the gene varies from tissue to tissue, and there is no correlation between enzyme activity and growth rate. The difference in activity between High and Low lines is due to the amount of active enzyme, not to an endogeneous activator or inhibitor. There was no isozymic difference in alpha-mannosidase.
mesh_terms: D000483:Alleles; D000818:Animals; D012831:Bombyx / Q000201:enzymology / Q000235:genetics*; D006458:Hemolymph / Q000201:enzymology; D008361:Mannosidases / Q000235:genetics*; D043323:alpha-Mannosidase
chemical_list: D008361:Mannosidases; D043323:alpha-Mannosidase