Pregnancy-specific beta 1-glycoprotein (SP1) levels measured by nephelometry in serum from women with vaginal bleeding in the first half of pregnancy.
Pregnancy-specific beta 1-glycoprotein (SP1) levels were measured by nephelometry in sera from 107 women admitted to hospital because of vaginal bleeding in weeks 8 to 20 of pregnancy. The SP1 results were compared with those in single samples from 655 women and serial samples from 9 women with uncomplicated single pregnancies in the same period. The possibility of predicting the outcome of a pregnancy complicated by vaginal bleeding was calculated on the basis of the SP1 level on admission to hospital. In 65% a normal SP1 value predicted continuation of pregnancy, whereas a low SP1 value invariably predicted spontaneous abortion.
D000022:Abortion, Spontaneous / Q000097:blood; D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009391:Nephelometry and Turbidimetry; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood*; D011257:Pregnancy Proteins / Q000032:analysis*; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis*; D011379:Prognosis; D012016:Reference Values; D014592:Uterine Hemorrhage / Q000097:blood*
D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins