The dimeric structure of carcinoembryonic antigen (CEA).
The results of SDS-polyacrylamide gel electrophoresis and cross-linking experiments indicated that carcinoembryonic antigen is a dimer composed of two identical or closely similar noncovalently bound subunits, dissociating on heating in the presence of SDS. The dissociation is reversible upon the detergent removal.
D000230:Adenocarcinoma / Q000276:immunology*; D002272:Carcinoembryonic Antigen / Q000302:isolation & purification*; D003110:Colonic Neoplasms / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology / Q000556:secondary*; D046911:Macromolecular Substances; D008970:Molecular Weight
D002272:Carcinoembryonic Antigen; D046911:Macromolecular Substances