[The iron-sulfur center N-2 from NADH-dehydrogenase during direct and reverse electron transport in the mitochondria of rat liver and the yeast Endomyces magnusii].
A dramatic decrease of the rate of transport of reducing equivalents from NADH to coenzyme Q was observed in the 4th metabolic state (by Chance). It was suggested that this decrease is due to the increase of total time of transition from the structural nonequilibrium state to the equilibrium one of the N-2 center. The structural nonequilibrium state of the center N-2 was observed only under the energy-dependent reverse electron transport, when the substrates for the reduction of coenzyme Q were used.
D000818:Animals; D001203:Ascomycota / Q000201:enzymology*; D003579:Cytochrome Reductases / Q000378:metabolism*; D004579:Electron Transport; D007506:Iron-Sulfur Proteins / Q000378:metabolism*; D007700:Kinetics; D008667:Metalloproteins / Q000378:metabolism*; D008928:Mitochondria / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology*; D009245:NADH Dehydrogenase / Q000378:metabolism*; D051381:Rats; D004718:Saccharomycetales / Q000201:enzymology*
D007506:Iron-Sulfur Proteins; D008667:Metalloproteins; D003579:Cytochrome Reductases; D009245:NADH Dehydrogenase
Issledovanie zhelezosernogo tsentra N-2 NADN-degidrogenazy pri priamom i obratnom transporte élektronov v mitokhondriiakh pecheni krys i drozhzheĭ Endomyces magnusii.