title: Current explorations in psychoimmunology.
abstract: Psychoimmunology is a new discipline linking psychological and immunological events. Studies to date have shown parallels between animal studies which measure response to stress and human reaction to loss, such as bereavement. Stein et al., have studied T and B lymphocytes in a bereaved population, noting suppression of function for six months to one year after a loss. Bartrop has found similar correlations. Gottschalk reviewed leukocyte function in depressed patients, finding a correlation between degree of depression and suppressed chemiluminescence. Udelman attempted a correlation between immunity and psychological states. Correlations were found between hope and T- and B-cell counts. The importance of psychoimmunology is underscored by the measurable impact of emotions on the body's defenses. It would seem reasonable to assume that adequate psychological defenses would be of aid in reducing vulnerability to illness. Thus, the psychotherapist is confronted by a newly measurable challenge to aid in control of not only emotional, but also physical illness. The enhancement of immunocompetence is a truly essential goal in prevention of illness.
mesh_terms: D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D011602:Psychophysiologic Disorders / Q000276:immunology*; D013315:Stress, Psychological / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology