title: [Antisilicotic action and side effects of polypyridylethyl-methacrylate iodomethylate].
abstract: Antisilicotic and side effects of a new polymer synthetized on the basis of polymethacrylic acid were studied. The polymer not only inhibited the development of silicotic sclerosis but also induced its partial reverse development. As regards the effect intensity it appeared to be equal to highly effective polyvinylpyridine-N-oxide. The data obtained indicate the necessity of a further study of the new antisilicotic polymer with a purpose of recommending it for clinical trials.
mesh_terms: D000818:Animals; D004353:Drug Evaluation, Preclinical; D008768:Methylmethacrylates / Q000009:adverse effects / Q000627:therapeutic use*; D011144:Polyvinylpyridine N-Oxide / Q000627:therapeutic use; D051381:Rats; D012829:Silicosis / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors
chemical_list: D008768:Methylmethacrylates; C015474:polypyridylethylmethacrylate; D011144:Polyvinylpyridine N-Oxide
vernacular_title: O protivosilikoticheskom i pobochnom deĭstvii ĭodmetilata polipiridilétilmetakrilata.