Adult T-cell leukemia occurring in mother and son.
We report two cases of adult T-cell leukemia in which the disease developed in a mother, aged 62 years, and her son, aged 41 years, less than four months apart. Both mother and son showed abnormal karyotypes and high titers of adult T-cell leukemia-associated antibody.
D000328:Adult; D000912:Antibodies, Neoplasm / Q000032:analysis; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes
D000912:Antibodies, Neoplasm