Taxonomy of actinomycetes capable of hydroxylation of ML-236B (compactin).
Three actinomycetes having capability of 3 beta-hydroxylation of ML-236B were isolated from soil samples collected in Australia. Strain SANK 62781 was identified as Nocardia autotrophica. Strain SANK 62881 and strain SANK 62981 were identified as new subspecies of N. autotrophica for which the name N. autotrophica subsp. canberrica and N. autotrophica subsp. amethystina are proposed, respectively. The type strains of N. autotrophica subsp. canberrica and N. autotrophica subsp. amethystina are ATCC 35203 and ATCC 35204.
D000900:Anti-Bacterial Agents / Q000378:metabolism*; D003470:Culture Media; D006900:Hydroxylation; D008148:Lovastatin / Q000031:analogs & derivatives*; D008855:Microscopy, Electron, Scanning; D009281:Naphthalenes / Q000378:metabolism*; D009615:Nocardia / Q000145:classification* / Q000648:ultrastructure; D013045:Species Specificity
D000900:Anti-Bacterial Agents; D003470:Culture Media; D009281:Naphthalenes; C012258:mevastatin; D008148:Lovastatin