Prognostic factors in neuroblastomas.
The clinical and histological factors affecting prognosis for 70 patients with neuroblastomas were tested with regression analysis. Generalized tumor disease was found to be of primary importance. Significant predictors for prognosis in patients without distant metastases were operation, with or without other therapy, age less than one year and histology. When all recorded factors were analyzed the explanation value only reached 0.42. This indicates that the variation in prognosis depends upon other factors as well.
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000473:pathology* / Q000628:therapy; D000328:Adult; D002114:Calcinosis; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008161:Lumbosacral Region; D008297:Male; D009210:Myofibrils / Q000473:pathology; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D013899:Thoracic Neoplasms / Q000473:pathology* / Q000628:therapy