title: [Effect of thyrostatic therapy on various immunologic indices in patients with diffuse toxic goiter].
abstract: The influence of thyrostatic therapy upon immunoglobulin A, M and G serum concentrations and lymphocytic blast-cell transformation in thyroglobulin and PHA presence in patients with diffuse toxic goiter was studied. The results of the immunological test used do not define quite accurately changes in clinical manifestations of the disease. In the majority of patients disorders of the humoral and/or cell immunity persist during the thyrotoxicosis compensatory stage. A tendency towards normalization or normalization of the parameters studied of T- and B-immune systems is seen under the action of thyrostatic therapy.
mesh_terms: D000328:Adult; D000917:Antibody Formation / Q000187:drug effects; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000276:immunology*; D007111:Immunity, Cellular / Q000187:drug effects; D007136:Immunoglobulins / Q000032:analysis; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008713:Methimazole / Q000627:therapeutic use*; D010835:Phytohemagglutinins / Q000494:pharmacology; D013601:T-Lymphocytes / Q000276:immunology*; D013954:Thyroglobulin / Q000494:pharmacology
chemical_list: D007136:Immunoglobulins; D010835:Phytohemagglutinins; D008713:Methimazole; D013954:Thyroglobulin
vernacular_title: Vliianie tireostaticheskoĭ terapii na nekotorye pokazateli immuniteta u bol'nykh diffuznym toksicheskim zobom.