title: Flash-induced nystagmus (FIN) and the vestibular system in the rabbit.
abstract: Flash-induced nystagmus (FIN) was found more often in albino than in pigmented rabbits. Incremental and decremental phase mainly showed exponential change in SPV, but linear change was seen as well with apparent time constant of 5-40 sec. FIN was unaltered by rendering the stimulated eye akinetic. Lesioning the nucleus of the optic tract (NOT) on one side abolished FIN and OKN responses from the other side. Bilateral labyrinthectomy led to a diminished response and after-responses were lost. Algebraic addition was shown if FIN was combined with vestibular reflex eye movements. The gain of these reflexes was enhanced. FIN may be specified as a type of nystagmus that is evoked by monocular essentially open-loop stimulation of the crossed ('subcortical') optic pathway. Direction-selective elements in the retina may play a specific role in that their predominant orientation gives rise to abduction nystagmus during on/off stimulation by flashes.
mesh_terms: D000818:Animals; D005074:Evoked Potentials, Visual; D009760:Nystagmus, Physiologic; D010775:Photic Stimulation; D011817:Rabbits; D014722:Vestibule, Labyrinth / Q000502:physiology*