A colony-stimulating-factor-producing cell line derived from mouse bone marrow cells transfected with adenovirus DNA.
A unique fibroblastoid cell line, BMA1, has been established from bone marrow cells of a DDY mouse transfected with adenovirus 5 DNA. BMA1 cells expressed adenoviral early antigens and BMA1-conditioned medium contained mouse granulocyte/macrophage colony-stimulating factor(s). The DNA transfection technique may be useful in establishing cell lines from bone marrow and analyzing the regulation of hemopoiesis.
D000256:Adenoviridae; D000818:Animals; D001853:Bone Marrow / Q000378:metabolism* / Q000473:pathology; D002460:Cell Line; D003115:Colony-Stimulating Factors / Q000096:biosynthesis*; D004279:DNA, Viral; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D014162:Transfection
D003115:Colony-Stimulating Factors; D004279:DNA, Viral