title: [Changes in the renin-aldosterone system after unilateral portalization of adrenal and renal blood in patients with arterial hypertension].
abstract: Twenty-one patients with severe arterial hypertension were operated on using an original procedure, which consisted in creating a left-side renoportal venous anastomosis and right-side adrenalectomy. A considerable hypotensive effect was noted at both early and late follow-up. A drop in vascular peripheral resistance as a result of decreased blood aldosterone and cortisol levels as well as sodium elimination was found to be the principal mechanism of the hypotensive effect.
mesh_terms: D000311:Adrenal Glands / Q000098:blood supply*; D000315:Adrenalectomy; D000328:Adult; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006973:Hypertension / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000601:surgery*; D011184:Postoperative Period; D012082:Renal Veins / Q000601:surgery*; D012084:Renin-Angiotensin System; D014680:Veins / Q000601:surgery
chemical_list: D006854:Hydrocortisone
vernacular_title: Izmeneniia v renin-al'dosteronovoĭ sisteme pri odnostoronneĭ portalizatsii nadpochechnikovoĭ i pochechnoĭ krovi u bol'nykh s arterial'noĭ gipertenzii.