[Essential headache as an equivalent to a withdrawal syndrome: experience with naloxone].
The Authors, starting with the hypothesis that could exist a correlation between the opiate withdrawal and the migraine crisis, used the naloxone, opiate pure antagonist, in order to induced the migraine crisis. 30 patients affected by migraine were studied; naloxone was administered acutely (2 mg e.v.) during the asintomatic period. The naloxone administration never caused the migraine crisis. The patients didn't complain variations regarding the psycho-physical status or the monitored clinical parameters.
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000139:chemically induced* / Q000209:etiology; D009270:Naloxone; D009294:Narcotics; D013375:Substance Withdrawal Syndrome
D009294:Narcotics; D009270:Naloxone
La cefalea essenziale come equivalente della sindrome di astinenza: esperienza col naloxone.