Superoxide dismutase in mouse brain, liver and heart in the presence and absence of dietary vitamin E1.
Three groups of weanling mice, 8 to a group, were fed three different diets for a 12-month period. The first group was fed a basal diet deficient in vitamin E, the second group was fed the basal diet plus 30 mg/kg diet d-alpha-tocopheryl acetate and the third group, the basal diet plus 300 mg/kg diet d-alpha-tocopheryl acetate. After 12 months, superoxide dismutase activity was measured in the liver, brain and heart. The enzyme activity in the liver was found to be 10 times the activity in either the brain or the heart. Dietary alpha-tocopherol did not influence superoxide dismutase activity in any of the tissues studied.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D005260:Female; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009206:Myocardium / Q000201:enzymology*; D013482:Superoxide Dismutase / Q000378:metabolism*; D014810:Vitamin E / Q000494:pharmacology; D014811:Vitamin E Deficiency / Q000201:enzymology*
D014810:Vitamin E; D013482:Superoxide Dismutase