[Changes in oxygen tension in the cerebral cortex during hemodilution].
Wistar rats were subjected to gradual blood replacement with 7% albumin (hemodilution). Hematocrit and mean arterial pressure were measured periodically. Polarographic platinum microelectrodes with a tip 3-8 microns in diameter were used to study variation of oxygen tension (pO2) in the brain cortex during hemodilution. Some areas showed a significant decrease in the brain pO2 after hematocrit dropped to 30%. In animals with an initially low pO2 (13.1 +/- 1.7 mm Hg), this parameter decreased more slowly than in rats with a higher basic pO2 (24.5 +/- 1.7 mm Hg).
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D006400:Hematocrit; D006438:Hemodilution; D010100:Oxygen / Q000502:physiology*; D010313:Partial Pressure; D051381:Rats; D011919:Rats, Inbred Strains
D010100:Oxygen
Izmeneniia napriazheniia kisloroda v kore bol'shogo mozga pri gemodiliutsii.