title: [Effect of pentagastrin on the closing pressure of the inferior esophageal sphincter and gastroesophageal reflux].
abstract: By means of pull--through perfusion manometry and by means of continuous intraoesophageal pH measurements comparative study on a uniform group of patients (n = 34) has shown that pentagastrin (Acignost R) at a dosage of 6 mg/kg body weight administered subcutaneously increases mean sphincter pressure and total reflux duration.
mesh_terms: D002446:Celiac Disease / Q000150:complications; D002769:Cholelithiasis / Q000150:complications; D004381:Duodenal Ulcer / Q000150:complications; D004941:Esophagitis / Q000150:complications; D004943:Esophagogastric Junction / Q000187:drug effects*; D005260:Female; D005764:Gastroesophageal Reflux / Q000139:chemically induced*; D006551:Hernia, Hiatal / Q000150:complications; D006801:Humans; D008297:Male; D010418:Pentagastrin / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013276:Stomach Ulcer / Q000150:complications
chemical_list: D010418:Pentagastrin
vernacular_title: Deĭstvie pentagastrina na zamykaiushchie davlenie nizhnego sfinktera pishchevoda i na gastroézofageal'nyĭ refliuks.