Open-angle glaucoma associated with posterior polymorphous dystrophy. A clinicopathologic study.
Clinical and histopathologic features of a 62-year-old black man with posterior polymorphous dystrophy and open-angle glaucoma requiring trabeculectomy are reported. The surgical procedure was modified to allow en bloc resection of the deep limbal tissue and peripheral iris. Light and electron microscopy of the specimen revealed a high insertion of the iris into the posterior portion of the trabecular meshwork with compression of the intertrabecular spaces. These findings are similar to changes that have been reported in primary congenital glaucoma and suggest a developmental anomaly of the anterior chamber angle in this form of glaucoma associated with posterior polymorphous dystrophy.
D003315:Cornea / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D003886:Descemet Membrane / Q000473:pathology; D004727:Endothelium / Q000473:pathology; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D007498:Iris / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D014129:Trabecular Meshwork / Q000473:pathology