A new analgesic drug combination in the horse.
A xylazine and butorphanol drug combination produced minimal and transient hemodynamic effects and no significant respiratory depression when administered to 6 healthy horses. Combining xylazine and butorphanol produced a synergistic analgesic effect and provided good chemical restraint for a standing surgical procedure.
D000698:Analgesia / Q000662:veterinary*; D000818:Animals; D002077:Butorphanol / Q000008:administration & dosage*; D002302:Cardiac Output / Q000187:drug effects; D004338:Drug Combinations; D006339:Heart Rate / Q000187:drug effects; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D009019:Morphinans / Q000008:administration & dosage*; D012119:Respiration / Q000187:drug effects; D013843:Thiazines / Q000008:administration & dosage*; D014991:Xylazine / Q000008:administration & dosage*
D004338:Drug Combinations; D009019:Morphinans; D013843:Thiazines; D014991:Xylazine; D002077:Butorphanol