New embolization method using estrogen: effect of estrogen on microcirculation.
To ascertain the mechanism of action of estrogen administered by a new embolization method, developed by the authors as a treatment method for dural arteriovenous malformations, conjugated estrogens were injected into the mesenteric artery of rabbits, and microcirculatory changes in the dominant areas were studied biomicroscopically. Conjugated estrogen induced sludging and stasis in the microcirculation, approximately in proportion to the concentration and dose.
D000818:Animals; D001921:Brain / Q000098:blood supply; D004388:Dura Mater; D004621:Embolization, Therapeutic; D004967:Estrogens / Q000008:administration & dosage*; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy*; D008833:Microcirculation / Q000187:drug effects; D011817:Rabbits
D004967:Estrogens