Desipramine in the treatment of hypersomnolence following abrupt cessation of cocaine use.
Two heavy abusers of cocaine experienced dysphoric hypersomnolent withdrawal following abrupt cessation of use. Desipramine quickly reversed the withdrawal symptoms in both patients, although it did not prevent their future use of cocaine.
D000328:Adult; D003042:Cocaine / Q000009:adverse effects*; D003891:Desipramine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012893:Sleep Wake Disorders / Q000139:chemically induced / Q000188:drug therapy*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000209:etiology; D019966:Substance-Related Disorders / Q000534:rehabilitation
D003042:Cocaine; D003891:Desipramine