Effect of intravenous infusion on development of pulmonary oedema after inhalation injury.
Last year, after a systematic search of pathological and patho-physiological changes of inhalation injury in dogs, we recorded severe pulmonary oedema as early as 2 h postburn (the earliest monitoring time designed in experiment) on dogs inflicted with both body surface and severe respiratory burns without any fluid replacement during the whole course of experiment. In an analysis of cases admitted into our burn centre in the past ten years, we also found that there was no definite relationship between the incidence and severity of pulmonary oedema occurring in severe burn patients and the amount of fluid infused in the early burn phase. These facts led us to the following experiment designed to study the effect of intravenous infusion on development of pulmonary oedema after severe burns complicated with inhalation injuries.
D000818:Animals; D002059:Burns, Inhalation / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D004285:Dogs; D005440:Fluid Therapy; D011654:Pulmonary Edema / Q000209:etiology / Q000517:prevention & control*; D012119:Respiration