title: Chronobiological aspects of headache syndromes due to sellar or pituitary pathology.
abstract: A chronobiological study was carried out in headache syndromes due to empty sella or to pituitary G.H.- and PRL-secreting adenomas. In the empty sella syndrome only the chrono-organization of G.H. secretion was disturbed, whereas pl. PRL exhibited the usual circadian pattern. The circadian rhythms of pl. G.H. and pl. PRL were abolished in G.H.- and PRL-secreting pituitary tumors, respectively, and were again detectable when patients were cured by selective transsphenoidal adenomectomy. A normal circadian rhythmicity of pl. cortisol was demonstrable in the empty sella syndrome and in pituitary adenomas, both before and after surgery.
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000378:metabolism; D000328:Adult; D002940:Circadian Rhythm; D004652:Empty Sella Syndrome / Q000150:complications*; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D006261:Headache / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications*; D011388:Prolactin / Q000378:metabolism; D013577:Syndrome
chemical_list: D011388:Prolactin; D013006:Growth Hormone