title: Retrograde HRP identification of neurons in the rhombencephalon and spinal cord of the rat that project to the dorsal mesencephalon.
abstract: Neurons in the rhombencephalon and spinal cord of the rat that project to the dorsal midbrain were identified using the HRP retrograde neuroanatomical tracing method. Retrogradely labeled neurons were most numerous in the reticular formation, specifically in nucleus pontis oralis, caudalis, and gigantocellularis and in the sensory trigeminal complex. Neurons that project were also found in certain raphe nuclei, the parabrachial nuclei, the deep cerebellar nuclei, the vestibular cochlear complex, and the spinal cord. The diverse distribution of neurons that project to the midbrain is understandable in the context of the known diverse functions of the region, which include a role in sexual and other behaviors, nociception, and various autonomic functions.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology*; D002529:Cerebellar Nuclei / Q000166:cytology; D005260:Female; D006735:Horseradish Peroxidase; D008297:Male; D008636:Mesencephalon / Q000166:cytology*; D009474:Neurons / Q000166:cytology*; D010146:Pain / Q000503:physiopathology; D010544:Peroxidases; D051381:Rats; D012154:Reticular Formation / Q000166:cytology; D013116:Spinal Cord / Q000166:cytology*; D014279:Trigeminal Nucleus, Spinal / Q000166:cytology
chemical_list: D006735:Horseradish Peroxidase; D010544:Peroxidases