title: Identification of lead sources in California children using the stable isotope ratio technique.
abstract: Two case studies are presented which apply the lead isotope ratio method to the identification of lead sources in 12 Oakland, California children. One study examined lead sources in 10 children, ages 3 to 15 yr, living together as an extended family in dilapidated housing close to a busy freeway. Eight children had elevated blood lead levels (greater than or equal to 30 micrograms/dl) and 6 children also had elevated erythrocyte protoporphyrin levels (greater than or equal to 50 micrograms/dl). A second case study examined 2-yr-old male twins, both with elevated blood lead and erythrocyte protoporphyrin levels, living in a modest, but well maintained inner city duplex apartment. Paint and surface soil samples collected in and around both households had high lead concentrations. Paint concentrations ranged from 2.9 to 273 mg/g and surface soil concentrations from 0.48 to 7.1 mg/g. The isotopic ratios of lead in the blood of these children were close to the average lead ratios of paints from exterior walls and to the lead ratios of surface soils in adjacent areas where the children played. In both case studies, the data suggest that the lead in the soil was derived mainly from weathering of lead-based exterior paints and that the lead-contaminated soil was a proximate source of lead in the blood of the children.
mesh_terms: D000293:Adolescent; D002140:California; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007554:Isotopes; D007854:Lead / Q000097:blood*; D008297:Male; D011524:Protoporphyrins / Q000097:blood; D012989:Soil Pollutants / Q000032:analysis
chemical_list: D007554:Isotopes; D011524:Protoporphyrins; D012989:Soil Pollutants; D007854:Lead