Complete recovery from hepatitis B and associated hemolysis in a patient with underlying T-cell deficiency.
A 17-yr-old woman presented with acute hepatitis B. She had preexisting well-documented immune deficiency, clinically apparent as chronic mucocutaneous candidiasis, and recurrent severe viral infections. Life-threatening but spontaneously resolving Coombs-negative hemolysis complicated the recovery phase. Complete healing of the hepatitis with disappearance of hepatitis B surface antigen from serum and normal hepatitis B surface antibody and hepatitis B core antibody production occurred in spite of T-cell dysfunction.
D000208:Acute Disease; D000293:Adolescent; D005260:Female; D006461:Hemolysis; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D013601:T-Lymphocytes / Q000276:immunology
D006514:Hepatitis B Surface Antigens