Reactivity of histiocytosis X cells with monoclonal antibodies.
Histiocytosis X cells were demonstrated to react with T6 antigen as well as with the M1 and I1 markers of monocytes using immuno-electron microscopy and double labeling immunofluorescence technique. The data confirm the close relationship existing between histiocytic X cells, Langerhans cells and dendritic cells, and suggest to consider the T6 antigen either as an early differentiation marker of thymocytes or as a functional marker of Mononuclear Phagocyte System subpopulations.
D000911:Antibodies, Monoclonal; D002454:Cell Differentiation; D002478:Cells, Cultured; D006646:Histiocytosis, Langerhans-Cell / Q000276:immunology*; D006801:Humans; D008854:Microscopy, Electron; D009000:Monocytes / Q000276:immunology*; D010586:Phagocytes / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal