Quantitative variations in polymorphic types of human red cell esterase D.
Human red cell esterase D was analysed quantitatively in Japanese samples. Among the three esterase D phenotypes there was a significant difference in catalytic activity, with an approximate ratio of 7:5:3 for EsD 1, EsD 2-1 and EsD 2. With a few inter-type individuals, the distribution of their activity values was plotted in a tri-modal curve. These results suggest that the esterase D system in human red cells is qualitatively and even quantitatively controlled by genes.
D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000097:blood* / Q000235:genetics; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007527:Isoenzymes / Q000097:blood* / Q000235:genetics; D010641:Phenotype; D011110:Polymorphism, Genetic
D007527:Isoenzymes; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; C020118:ESD protein, human