The cutaneous lymphomas with convoluted nucleus. Analysis of thirty-nine cases.
The clinical and histopathologic findings in thirty-nine cases of cutaneous lymphoma characterized by a proliferation of convoluted cells were reviewed. Thirty patients (77%) presented with erythematous or papular lesions (group I). The remaining nine patients (23%) presented with cutaneous nodules or tumors without erythematous lesions (group III). Histologically, the polymorphous infiltration was the common feature in both groups, but the presence of epidermotropism in group I was contrasted to the absence of epidermotropism in group II disease. The patients in group I had a higher median age (54 years) than those in group II (35 years), and a more favorable 3-year survival rate (44%) than that of the latter (19%). An evolution occasionally occurred from the epidermotropic to the nonepidermotropic form, followed by a poor clinical course. When the skin lesions were nonepidermotropic , irrespective of preceding clinical course, the prognosis was poor.
D000328:Adult; D000368:Aged; D002455:Cell Division; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000401:mortality / Q000473:pathology; D011379:Prognosis; D012751:Sezary Syndrome / Q000401:mortality / Q000473:pathology; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology*; D013601:T-Lymphocytes; D009626:Terminology as Topic