Some stochastic models for plasmid copy number.
Some stochastic models for the copy number of plasmids in a cell line are studied. When considering the behavior of copy number in the whole cell line, the theory of multitype branching processes is appropriate. Attention is paid to the cure rate in the cell line, and the asymptotic fractions of cells containing a given number of plasmids. These quantities are used to compare the models numerically.
D004261:DNA Replication; D008954:Models, Biological; D010957:Plasmids; D011336:Probability; D013269:Stochastic Processes