title: [Coagulation disorders in acute cranio-cerebral injuries].
abstract: Marked coagulation defects which have a very high mortality rate can arise following acute head injury. Damage to brain tissue leads to the release of substances promoting coagulation which can enter the vascular system and activate the enzyme cascade leading to clot formation. The more widespread cerebral damage is, the greater is the likelihood of clinically relevant DIC occurring. By carrying out clotting tests and taking therapeutic measures where necessary, a potentially lethal outcome can be avoided.
mesh_terms: D000208:Acute Disease; D001930:Brain Injuries / Q000150:complications*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000209:etiology*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans
chemical_list: D006493:Heparin
vernacular_title: Gerinnungsstörungen beim akuten Schädel-Hirn-Trauma.