title: The postnatal metabolic development of the nucleus commissuralis and nucleus medialis of the nucleus tractus solitarius.
abstract: The ontogeny of the metabolic requirements in the nucleus commissuralis (NC) and nucleus medialis (NM) of the nucleus tractus solitarius was studied in the postnatal rat using the [3H]2-deoxy-D-glucose autoradiography technique. It was found that the metabolic requirements in the NC and NM are not constant between 2 and 12 weeks of age. A high level of metabolic activity at 2 and 8 weeks is contrasted by a lower level at 4 and 12 weeks. The apparent changes in metabolic requirements are not related to the changes in blood pressure of the rats or neuronal densities of the subnuclei which occur as the rats mature, or to exchange vessel densities of the subnuclei. Thus the higher energy requirements of the NC and NM at 2 and 8 weeks of age suggest that developmental and/or functional processes are more active at these stages.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002452:Cell Count; D003847:Deoxyglucose / Q000378:metabolism; D008526:Medulla Oblongata / Q000098:blood supply / Q000166:cytology / Q000254:growth & development / Q000378:metabolism*; D009474:Neurons / Q000166:cytology; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
chemical_list: D014316:Tritium; D003847:Deoxyglucose