title: Smoking in pregnancy: relevance of maternal screening tests on fetal outcome.
abstract: A number of laboratory parameters were estimated in 54 pregnant women in order to assess whether changes induced by smoking could reflect weight gain in the fetus. There was a significant correlation between maternal weight gain index, oestriol levels, antithrombin III levels and reticulocyte synthesis with infant and placental weight gain. One or more of these tests was found abnormal in 27% of normal pregnant patients, 72% of light smokers, and 89% of heavy smokers. Several other parameters were found to be significantly altered in smoking compared to non-smoking pregnant patients; however, these bore no relationship to infant and placental parameters. These studies indicate that laboratory assessment of a number of maternal parameters could be of some value in determining the likelihood of depressed weight gain by infants of smoking mothers.
mesh_terms: D001724:Birth Weight; D001777:Blood Coagulation; D001835:Body Weight; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology; D010976:Platelet Count; D011247:Pregnancy; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis; D012156:Reticulocytes / Q000502:physiology; D012306:Risk; D012907:Smoking
chemical_list: D011268:Pregnancy-Specific beta 1-Glycoproteins; D003165:Complement System Proteins