[Glucose-6-phosphate dehydrogenase and succinate dehydrogenase in metastatic cells of Lewis lung carcinoma].
By the experimental model of the Lewis lung carcinoma we studied the activity of glucose-6-phosphate-dehydrogenesis (G6PDH) and succinic-dehydrogenesis (SDH) in the carcinoma itself, the lung metastases, the peripheral blood. A set of carcinoma, lung sections, peripheral blood smears were studied by histochemical techniques day by day since the 3rd day to the 15th one after the carcinoma grafting. The reported results allow us to conclude that G6PDH looks like a determinant of metastatic cell survival and growth and can be regarded as a marker of metastatic cells in the present model.
D000818:Animals; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis*; D008175:Lung Neoplasms / Q000201:enzymology* / Q000473:pathology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D013385:Succinate Dehydrogenase / Q000032:analysis*
D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase
Glucosio-6-fosfato deidrogenasi e succinodeidrogenasi in cellule metastatiche di carcinoma polmonare di Lewis.