title: [Skin reactions in the miniature pig following a single or fractionated local irradiation with 250 kVX-rays or 6.2 MeV neutron rays].
abstract: Skin areas of the miniature pig were irradiated locally with single fractionated (10 X Df in 12 days) doses of 250 kVX-rays or 6.2 MeV neutron rays. Depending on the neutron dose for single irradiations, the acute skin reactions up to 4 months following exposure yielded RBE values significantly less than 3.0, related to a neutron dose of 8 Gy and an X-ray dose of 24.2 Gy. When giving fractionated doses, RBE values greater than 3.1 were obtained, related to a neutron dose fraction of 1.2 Gy and an X-ray dose fraction of 3.7 Gy. For late effects 2 years after a single exposure, RBE values significantly greater than 2.3 were obtained, related to a neutron dose of 8 Gy and an X-ray dose of 18.6 Gy. Fractionated neutron irradiation yielded, as with the acute damage, RBE values greater than 3.1, related to a neutron dose fraction of 1.2 Gy and an X-ray dose fraction of 3.7 Gy. The tendency to higher RBE values for late against acute skin reactions could not be statistically verified by the present results.
mesh_terms: D000818:Animals; D002369:Castration; D005260:Female; D008297:Male; D009502:Neutrons; D011829:Radiation Dosage; D012867:Skin / Q000528:radiation effects*; D013552:Swine; D013556:Swine, Miniature; D013997:Time Factors
vernacular_title: Hautreaktionen beim Miniaturschwein nach einzeitiger oder fraktionierter Lokalbestrahlung mit 250-kV-Röntgen- oder 6,2-MeV-Neutronenstrahlen.