title: Responsiveness of human lung diploid fibroblast ageing in vitro to epidermal growth factor: saturation density and lifespan.
abstract: Epidermal growth factor (EGF) in culture medium increased the saturation density of human diploid fibroblasts. In the first half of their in vitro lifespan the magnitude of the EGF-induced augmentation increased and in the second half, decreased. Their lifespan was not extended by continuous exposure to EGF.
mesh_terms: D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects*; D002478:Cells, Cultured; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D006801:Humans; D008168:Lung / Q000166:cytology
chemical_list: D004815:Epidermal Growth Factor