Isomeric purity and supersaturation of iopamidol.
We have found that iopamidol 370 mg I/ml solutions may be greatly supersaturated and iopamidol 300 mg I/ml solutions slightly supersaturated at 4 degrees C and at 25 degrees C. The solubility and degree of supersaturation probably depend on the isomeric purity of the preparation. Some possible implications are discussed.
D003287:Contrast Media; D003460:Crystallization; D007479:Iopamidol; D007483:Iothalamic Acid / Q000031:analogs & derivatives*; D007536:Isomerism; D012995:Solubility; D013696:Temperature; D013997:Time Factors
D003287:Contrast Media; D007483:Iothalamic Acid; D007479:Iopamidol