Prevention and treatment of deep infection following total hip replacement.
Three different methods of prophylaxis in total hip replacement are discussed and evaluated: the systemic use of antibiotics, use of gentamicin-containing bone cement and the ultraclean technique. The lowest incidence of deep infection is achieved with a combination of the clean room and antibiotics either in local or systemic form. The results after revision using gentamicin-impregnated bone cement show that a healing rate of 80% is possible; however, there is a high risk of aseptic loosening during the postoperative course.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001843:Bone Cements; D004780:Environment, Controlled; D005839:Gentamicins / Q000627:therapeutic use; D006622:Hip Prosthesis; D006801:Humans; D009873:Operating Rooms; D011183:Postoperative Complications; D011292:Premedication; D012086:Reoperation; D012306:Risk; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D001843:Bone Cements; D005839:Gentamicins