Possible association of membrane and nuclear changes in gamma-irradiated rat thymocytes.
gamma-irradiated rat thymocytes were incubated in medium containing fresh rat serum. After 6 hours in culture, an equal dose dependency was noted for nuclear pyknosis and the loss of surface receptors to autologous erythrocytes. Decreased rosette formation preceded the expression of pyknosis. A possible relation between the membrane changes and pyknosis during interphase death of the thymocytes is discussed.
D000818:Animals; D002452:Cell Count; D002462:Cell Membrane / Q000528:radiation effects*; D002467:Cell Nucleus / Q000528:radiation effects*; D002470:Cell Survival; D003470:Culture Media; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D051381:Rats; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000528:radiation effects*
D003470:Culture Media