title: Pancreolauryl test. Evaluation of a tubeless pancreatic function test in comparison with other indirect and direct tests for exocrine pancreatic function.
abstract: The sensitivity and specificity of the pancreolauryl test was evaluated in comparison with the NBT-PABA test, the estimation of fecal chymotrypsin and fat, and the secretin-pancreozymin test in 168 patients with and without pancreatic disease. The overall sensitivity rate was as follows: pancreolauryl test 90%, NBT-PABA test 86%, fecal chymotrypsin 66%. In patients with pancreatic steatorrhea the sensitivity of the pancreolauryl test was 100%, the NBT-PABA test 97%, and the fecal chymotrypsin estimation 92%. The specificity of these tests was: pancreolauryl test 97.6%, fecal chymotrypsin 87%, and NBT-PABA test 81.8%. The pancreolauryl test may be recommended as a noninvasive easy-to-perform tubeless pancreatic function test with a sufficiently high sensitivity and specificity.
mesh_terms: D010129:4-Aminobenzoic Acid; D002766:Cholecystokinin; D002908:Chronic Disease; D002918:Chymotrypsin / Q000032:analysis; D005243:Feces / Q000032:analysis; D005452:Fluoresceins; D006801:Humans; D009580:Nitroblue Tetrazolium; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000175:diagnosis*; D012633:Secretin
chemical_list: D005452:Fluoresceins; D012633:Secretin; D009580:Nitroblue Tetrazolium; D002766:Cholecystokinin; C034833:fluorescein dilaurate; D002918:Chymotrypsin; D010129:4-Aminobenzoic Acid