title: Vertebrate class distribution of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase in serum.
abstract: Serum from numerous mammals and lower vertebrates contains an enzyme activity that is specific for the hydrolysis of the acetate moiety of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF, platelet activating factor). Acetylhydrolase (EC 3.1.1.47, 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase) was found in all mammalian sera with activity ranging from 11 (fetal calf) to 178 (rabbit) pmol acetate liberated/microliter serum/min. The enzyme is not present in avian serum but is a constituent of reptiles and bony fishes.
mesh_terms: D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D002417:Cattle; D002645:Chickens; D010856:Columbidae; D005333:Fetus; D005399:Fishes; D006041:Goats; D006168:Guinea Pigs; D006736:Horses; D007700:Kinetics; D011894:Rana pipiens; D012911:Snakes; D013045:Species Specificity; D013552:Swine; D014422:Turkeys; D014426:Turtles
chemical_list: C028207:1-alkyl-2-acetyl-sn-glycero-3-phosphocholine-acetylhydrolase; D002265:Carboxylic Ester Hydrolases