Peritoneal fluid prostanoids in unexplained infertility.
Elevated peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha have been reported in patients with biopsy-proved endometriosis. In this paper these peritoneal fluid prostanoids were measured in patients with unexplained infertility and a fertile control group matched for age and day of the menstrual cycle. A subgroup of the women with unexplained infertility demonstrated a marked elevation of both prostanoids (p less than 0.01). These elevations may serve to identify women in whom undetected endometriosis or some other peritoneal irritant is associated with infertility.
D000293:Adolescent; D000328:Adult; D001202:Ascitic Fluid / Q000032:analysis*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000276:immunology / Q000378:metabolism*; D011460:Prostaglandins F / Q000032:analysis* / Q000276:immunology; D013929:Thromboxane B2 / Q000032:analysis* / Q000276:immunology; D013931:Thromboxanes / Q000032:analysis*
D011460:Prostaglandins F; D013931:Thromboxanes; D013929:Thromboxane B2; C100006:prostaglandin F1