title: Comparison of radiation-induced radical yields in short peptides and constituent amino acids by detection of trapped oxygen isotope 18O.
abstract: This report compares the radiosensitivity of small polypeptides and constituent isolated amino acids using a novel technical approach. The radiation-induced oxygen isotope 18O trapping was measured by means of nuclear reactions. Most of the peptides reveal a higher sensitivity than a mixture of their constituent amino acids. This observation can be rationalized with a simple model which implies intramolecular energy transfer.
mesh_terms: D000596:Amino Acids / Q000528:radiation effects*; D004151:Dipeptides / Q000528:radiation effects*; D005609:Free Radicals; D005998:Glycine / Q000528:radiation effects; D007930:Leucine / Q000528:radiation effects; D008722:Methods; D010104:Oxygen Radioisotopes
chemical_list: D000596:Amino Acids; D004151:Dipeptides; D005609:Free Radicals; D010104:Oxygen Radioisotopes; C038361:leucylleucine; C015905:glycylleucine; D007930:Leucine; D005998:Glycine