title: Comparison of virulence of clones of two Trichomonas vaginalis strains by the subcutaneous mouse assay.
abstract: No statistical differences in virulence were found among five clones isolated from each of two Trichomonas vaginalis strains JH31A and Balt 42. The former strain, isolated from a patient showing no cervical epithelial abnormalities, caused relatively small subcutaneous lesions in mice [mean volume for the noncloned strain, 75.45 +/- 4.43 mm3 (n = 70); mean of means for cloned populations, 77.28 +/- 3.14 mm3 (n = 230)]. The latter, Balt 42, isolated from a woman with an in situ carcinoma of the cervix uteri, produced large subcutaneous abscesses in mice [mean volume for the noncloned strain, 202.28 +/- 12.53 mm3 (n = 55); mean of means for cloned populations, 200.48 +/- 13.72 mm3 (n = 264)]. The apparent homogeneity of T. vaginalis strains with regard to virulence reinforces the dependability of the subcutaneous mouse assay.
mesh_terms: D000038:Abscess / Q000473:pathology*; D000818:Animals; D003470:Culture Media; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains; D013045:Species Specificity; D014211:Treponemal Infections / Q000473:pathology*; D014246:Trichomonas vaginalis / Q000254:growth & development / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D003470:Culture Media