title: [Wiskott-Aldrich syndrome].
abstract: Current concepts of pathogenesis and therapy of Wiskott-Aldrich syndrome are discussed, along with demonstrating the case history of a patient with the clinical features of this rare disorder. In addition to the known symptoms there was an elevated blood monocyte count together with a decreased total number of lymphocytes. Immunological analysis of the mononuclear cell fraction revealed an imbalance between mature T-cells, "natural-killer"-cells and monocytes.
mesh_terms: D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007694:Killer Cells, Natural; D008231:Lymphopenia / Q000175:diagnosis; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009000:Monocytes; D013601:T-Lymphocytes; D014923:Wiskott-Aldrich Syndrome / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D008775:Methylprednisolone
vernacular_title: Wiskott-Aldrich Syndrom.