[Hypothyroidism and the Gougerot-Sjögren syndrome].
The signs of Sjögren's syndrome were systematically researched in 36 patients with hypothyroidism (myxoedema with atrophic thyroiditis in 32 cases, Hashimoto's thyroiditis in 4). In a quarter of these patients were noted separately submaxillary glands and/or parotids enlarged, buccal and/or lacrymal sicca syndromes, and antisalivaryy ducts antibodies. The histologic analysis of minor salivar glands revealed foci of lymphocytes and plasmocytes (grades 3 and 4 of Chisholm's classification) in 6 subjects. Similarities between the Sjögren's syndrome and the autoimmune thyroiditis were specified; their association in the same patients might be explained considering the genetic predisposition to these affections.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013966:Thyroiditis / Q000175:diagnosis / Q000276:immunology
Hypothyroïdie et syndrome de Gougerot-Sjögren.