title: Effects of voluntary exercise on sexual behavior in female rats.
abstract: In two experiments, ovariectomized rats given access to activity wheels showed significantly higher lordosis ratings following estradiol treatment than animals maintained in individual hanging cages. Estrogen-induced decreases in body weight also were greater in wheel-housed animals. We suggest that access to running wheels may alter responsiveness to estradiol.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D005082:Physical Exertion; D011187:Posture; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects
chemical_list: D004958:Estradiol