Development of a radioimmunoassay for 'Tamm-Horsfall-like' glycoprotein in serum and cerebrospinal fluid.
Affinity chromatography purification was combined with a radioimmunoassay for 'Tamm-Horsfall-like' glycoprotein. This enabled serum concentrations to be established and to demonstrate its presence in cerebrospinal fluid for the first time. This assay method used in different circumstances suggests a multifocal synthesis. Nevertheless, urinary Tamm-Horsfall glycoprotein so far must be distinguished from the serum or cerebrospinal fluid Tamm-Horsfall-like glycoprotein.
D000328:Adult; D002846:Chromatography, Affinity; D006801:Humans; D009088:Mucoproteins / Q000032:analysis* / Q000097:blood / Q000134:cerebrospinal fluid; D009422:Nervous System Diseases / Q000378:metabolism; D011863:Radioimmunoassay; D012016:Reference Values; D058949:Uromodulin
D009088:Mucoproteins; C548612:UMOD protein, human; D058949:Uromodulin