Red cell creatine in term and preterm, adequate and small for gestational age newborns after normal pregnancy or risk conditions. I. Statistical analysis of creatine in various groups of newborns.
The red cell creatine concentration was determined in 174 newborns (cord blood) and in 50 healthy adults. Normal values for term adequate for gestational age newborns without intrauterine and perinatal risk (n = 53) were established to lie significantly above those for adults. Newborns after risk pregnancies had higher mean creatine concentrations than those born after uneventful gestation. Small for gestational age (SGA) infants proved to have the lowest creatine concentration of all newborn groups. The creatine values of our SGA children suggested that not more than 20% of them had chronic intrauterine hypoxia. It is concluded that red cell creatine at birth may serve to characterize in retrospect erythropoietic dynamics in cases of intrauterine growth retardation and intrauterine risk.
D003401:Creatine / Q000097:blood*; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007236:Infant, Small for Gestational Age; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D012016:Reference Values; D012306:Risk
D003401:Creatine