Synthesis of a new potent anti-ulcer and gastric secretory inhibiting agent, (-)-cis-2,3-dihydro-3-(4-methylpiperazinylmethyl)-2-phenyl-1,5-benzothiazepin-4(5H)-one hydrochloride (BTM-1086), and related compounds.
D000818:Animals; D000897:Anti-Ulcer Agents / Q000138:chemical synthesis*; D005750:Gastric Juice / Q000378:metabolism*; D051379:Mice; D051381:Rats; D013841:Thiazepines / Q000138:chemical synthesis* / Q000494:pharmacology
D000897:Anti-Ulcer Agents; D013841:Thiazepines; C029165:BTM 1042