Cogan's syndrome: a treatable cause of neurosensory deafness.
Cogan's syndrome, nonsyphilitic interstitial keratitis associated with vestibuloauditory deficits, can vary in its presentation. This paper describes an unusual case in which deafness developed while the patient was receiving topical therapy with prednisolone and homatropine for mild bilateral iritis and right-sided nodular episcleritis. The 10-year-old boy's hearing improved dramatically with high-dose systemic steroid therapy. The importance of being aware that deafness may occur in children undergoing treatment for "routine" iritis is emphasized.
D002648:Child; D003638:Deafness / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007500:Iritis / Q000188:drug therapy; D007634:Keratitis / Q000175:diagnosis* / Q000188:drug therapy; D007759:Labyrinth Diseases / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D013577:Syndrome; D014326:Tropanes / Q000627:therapeutic use; D014722:Vestibule, Labyrinth
D014326:Tropanes; C100236:homatropine; D011239:Prednisolone