Production of penicillinases by certain penicillin-resistant bacteria. (C) factors affecting the activities of penicillinases produced by Staphylococcus aureus, S9.
The activities of penicillinases produced by Staphylococcus aureus, S9 were found to be affected by pH, temperature, substrate concentration and type of penicillin derivative used as a substrate. The optimal activities of penicillinases produced by S. aureus, S9 were obtained at pH 6, at 37 degrees C, 0.5-10 mu/ml penicillin G concentration, and by increasing the enzyme concentration.
D006863:Hydrogen-Ion Concentration; D010400:Penicillin G / Q000378:metabolism; D010405:Penicillinase / Q000096:biosynthesis*; D013211:Staphylococcus aureus / Q000201:enzymology*; D013696:Temperature
D010405:Penicillinase; D010400:Penicillin G