[Effect of trimethylglycine on lipid metabolism in experimental atherosclerosis in rabbits].
It has been shown in adult rabbits aged 8 months with experimental cholesterol atherosclerosis that administration of trimethylglycinee in a dose of 0.5 g/kg reduces the elevated content of total and ester-bound cholesterol, beta-lipoproteins, total lipids in the blood serum and that of total cholesterol and triglycerides in the liver. Little toxicity and high efficacy of trimethylglycin in experimental atherosclerosis make this compound prospective in the light of its use as an antisclerotic agent.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D001161:Arteriosclerosis / Q000188:drug therapy* / Q000378:metabolism; D001622:Betaine / Q000627:therapeutic use*; D003864:Depression, Chemical; D004353:Drug Evaluation, Preclinical; D005260:Female; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D011817:Rabbits; D013997:Time Factors
D001622:Betaine
Vliianie trimetilglitsina na lipidnyĭ obmen pri éksperimental'nom ateroskleroze u krolikov.