Persistent vegetating and keratotic lesions in patients with pemphigus vulgaris during immunosuppressive therapy.
We describe three patients with pemphigus vulgaris, who during treatment with low doses of immunosuppressive drugs developed persistent keratotic or vegetating skin lesions. Direct immunofluorescence (IF) examination of these lesions showed the typical findings of pemphigus.
D000051:Acantholysis / Q000209:etiology; D000368:Aged; D001379:Azathioprine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007642:Keratosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use
D011239:Prednisolone; D001379:Azathioprine