Possible new autosomal recessive syndrome with unusual renal histopathological changes.
We report a couple with repeated pregnancy loss--two spontaneous first trimester abortions and two stillbirths with diffuse hypoplasia of the renal tubules. Both parents have been investigated to exclude occult unilateral renal agenesis. We raise the possibility that this is a new autosomal recessive condition.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000026:Abortion, Habitual / Q000235:genetics; D000328:Adult; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D008297:Male; D011247:Pregnancy; D013577:Syndrome