title: Platelet monoamine oxidase and erythrocyte catechol-o-methyltransferase activity in alcoholism and controlled abstinence.
abstract: This study substantiates previous reports that low platelet monoamine oxidase (MAO) activity is associated with alcoholism. Catechol-o-methyltransferase (COMT) activity in erythrocytes of alcoholics did not differ from that of controls. In 20 male alcoholics low platelet MAO activity was found during the first 3 days after hospitalization. The MAO activity increased in the next 2 weeks of abstinence and then tended to decrease again.
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000201:enzymology*; D001792:Blood Platelets / Q000201:enzymology*; D002394:Catechol O-Methyltransferase / Q000097:blood*; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D013375:Substance Withdrawal Syndrome / Q000201:enzymology; D014363:Tryptamines / Q000097:blood; D014439:Tyramine / Q000097:blood
chemical_list: D014363:Tryptamines; D008995:Monoamine Oxidase; D002394:Catechol O-Methyltransferase; D014439:Tyramine