[Morphometric studies on the effect of 5-hydroxytryptamine creatinine sulfate and noradrenaline bitartrate on the growth of cerebral cortex explants in vitro].
Explants of cerebral cortex of neonatal rats were cultivated up to 15 DIV being treated with 5-hydroxytryptamine and noradrenaline, resp. Effects of exogenous transmitters on the growth of explants were investigated by means of morphometrical methods. Different effects on the growth depending on the duration of cultivation and the type of transmitter administered were found. Stimulatory influences have been seen to occur up to 4 DIV (noradrenaline) and up to 2 DIV (serotonin).
D000818:Animals; D000831:Animals, Newborn; D002454:Cell Differentiation / Q000187:drug effects*; D002540:Cerebral Cortex / Q000166:cytology / Q000187:drug effects*; D003404:Creatinine / Q000031:analogs & derivatives* / Q000494:pharmacology; D046508:Culture Techniques; D004338:Drug Combinations; D008938:Mitosis / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology*; D051381:Rats; D012701:Serotonin / Q000031:analogs & derivatives* / Q000494:pharmacology
D004338:Drug Combinations; C014050:creatinine sulfate, serotonin drug combination; D012701:Serotonin; D003404:Creatinine; D009638:Norepinephrine
Morphometrische Untersuchungen über den Einfluss von 5-Hydroxytryptamin-kreatininsulfat und Noradrenalin-bitartrat auf das Wachstum von Cerebrocortexexplantaten in vitro.