[Programs for the radiation and drug treatment of metastases of Ewing's sarcoma to the lungs in children].
As a result of total-local irradiation of the lung combined with polychemotherapy in patients with solitary metastases to the lungs, a 3-year survival in children was 52.7 +/- 12.1%, after local irradiation of the lungs and chemotherapy 30 +/- 11.8% of the patients. Combined treatment was well tolerated by pediatric patients. The results of the study have shown that radiation therapy of metastases of Ewing's sarcoma to the lungs with simultaneous polychemotherapy does not disturb external respiratory function even in a later period, the clinical manifestations of lung radiation reactions were seldom observed.
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002360:Carubicin / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D008558:Melphalan / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D009963:Orotic Acid / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage; D011879:Radiotherapy Dosage; D012512:Sarcoma, Ewing / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D014750:Vincristine / Q000008:administration & dosage
D003609:Dactinomycin; D014750:Vincristine; D009963:Orotic Acid; D003520:Cyclophosphamide; D011239:Prednisolone; D002360:Carubicin; D008558:Melphalan; D008727:Methotrexate
Programmy luchevogo i lekarstvennogo lecheniia metastazov sarkomy Iuinga v legkie u deteĭ.