Corticosteroid regulation of electrolytes.
It is proposed that sodium and potassium are regulated by varying the amounts of aldosterone, DOC, 18 OH-DOC, and 16 alpha 18 dihydroxy 11 deoxycorticosterone secreted in response to the nutritional load. The first two steroid hormones are for high potassium and the second two for low potassium intake. The nutritional load acts on potassium regulators primarily through its affect on serum potassium. The first and third steroids are proposed for low sodium intake.
D015070:18-Hydroxydesoxycorticosterone / Q000031:analogs & derivatives; D000305:Adrenal Cortex Hormones / Q000502:physiology*; D000450:Aldosterone / Q000502:physiology; D001692:Biological Transport; D003900:Desoxycorticosterone / Q000502:physiology; D006801:Humans; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D015070:18-Hydroxydesoxycorticosterone; D000305:Adrenal Cortex Hormones; D003900:Desoxycorticosterone; C011229:16 alpha,18-dihydroxydeoxycorticosterone; D000450:Aldosterone; D012964:Sodium; D011188:Potassium