Inhibitory effect of laser irradiation on dermal syngeneic tumor growth in mice.
Mice (C57BL/6) with established intradermal tumors (melanoma B-16 or glioma 203G1) and inbred Swiss mice (SWM/Ms) with established intradermal tumors (3-methylcholanthrene-induced sarcoma) were treated by either surgical excision or laser irradiation. Laser irradiation is effective in preventing the growth of dermal melanoma, and laser therapy may be more efficacious than surgical therapy for induction of a reaction against melanoma in mice. The results also suggest that determination of a suitable laser wavelength may be required to obtain a good therapeutic effect on each tumor.
D000818:Animals; D005910:Glioma / Q000473:pathology / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*