Formal genetics of isoniazid metabolism in man.
Complex segregation analysis of the isoniazid inactivator phenotype has shown the existence of a recessive gene and a multifactorial background. The phenotype is also influenced by age, sex and weight. The relevance of these findings to the grouping of individuals into slow and rapid inactivators is stressed.
D000107:Acetylation; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007538:Isoniazid / Q000378:metabolism* / Q000627:therapeutic use; D008297:Male; D008957:Models, Genetic; D010641:Phenotype
D007538:Isoniazid