Epidermolysis bullosa simplex blister fluid induces an intra-epidermal blister in cultured normal skin.
Organ cultures of normal human skin incubated with blister fluid from a patient with epidermolysis bullosa simplex (EBS) produced a clean intra-epidermal blister with histology similar to that of an EBS blister.
D000328:Adult; D001768:Blister / Q000209:etiology* / Q000473:pathology; D004820:Epidermolysis Bullosa / Q000473:pathology; D005260:Female; D006801:Humans; D009924:Organ Culture Techniques; D012867:Skin / Q000473:pathology; D013997:Time Factors