title: [Adjuvant chemotherapy for extranodal non-Hodgkin's lymphoma].
abstract: From 1976 to 1982, twenty-four cases with early stages (stage IE: 18, Stage IIE: 6) of extranodal non-Hodgkin's lymphomas were treated with combined modality of local treatment (radiation or operation) and an adjuvant chemotherapy consisting of vincristine, cyclophosphamide and prednisolone. Eighty-three percent of patients were diffuse histiocytic type. The most common sites of primary origin were in stomach; 13 patients and 7 patients in nasal or paranasal cavity. The disease-free survival rates at 5 years were 74% for stage IE and 80% for stage IIE, respectively. The result has suggested that adjuvant chemotherapy is a useful modality for extranodal non-Hodgkin's lymphoma.
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000097:blood / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D003520:Cyclophosphamide; D011239:Prednisolone