Gas-liquid chromatographic determination of propylene glycol in plasma and urine.
We describe a gas-chromatographic assay for propylene glycol in human plasma and urine. The method is sensitive enough to allow quantification of the compound at concentrations observed clinically. It requires no derivative preparation and takes only 13 min of chromatographic time.
D002072:Butylene Glycols / Q000097:blood; D002849:Chromatography, Gas; D004827:Epilepsy / Q000097:blood / Q000188:drug therapy; D005410:Flame Ionization; D006801:Humans; D010672:Phenytoin / Q000627:therapeutic use; D011409:Propylene Glycols / Q000097:blood* / Q000652:urine; D012015:Reference Standards; D013223:Statistics as Topic; D013997:Time Factors
D002072:Butylene Glycols; D011409:Propylene Glycols; C026978:2,3-butylene glycol; D010672:Phenytoin