Comparative enhancement of hyperthermia lethality on tumor cells by procaine and lanthanum.
The effects of procaine and lanthanum during hyperthermia of tumor cells were studied by trypan-blue exclusion and by 86Rb release from previously labeled Ehrlich ascites cells. The results indicate that while procaine shows no changes of cell viability and 86Rb outflux, lanthanum alters both parameters in a very significant way.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism / Q000628:therapy*; D002463:Cell Membrane Permeability / Q000187:drug effects; D003131:Combined Modality Therapy; D006979:Hyperthermia, Induced; D007811:Lanthanum / Q000627:therapeutic use*; D051379:Mice; D011343:Procaine / Q000627:therapeutic use*
D011343:Procaine; D007811:Lanthanum