title: Clinical evaluation of the 99mTc-diethyl-HIDA plasma clearance curve and observations on the third exponential term.
abstract: Blood clearance curves of 99mTc-HIDA have been evaluated in 18 healthy volunteers and 55 patients affected by chronic liver diseases. The slope (K) of the third exponential term of the blood clearance curve can be considered as an index of the 99mTc-diethyl-HIDA liver cell uptake; therefore, this parameter seems to be able to discriminate healthy volunteers from patients affected by hepatocellular dysfunction.
mesh_terms: D003201:Computers; D006801:Humans; D007098:Imino Acids / Q000097:blood*; D007700:Kinetics; D008107:Liver Diseases / Q000097:blood; D008657:Metabolic Clearance Rate; D013667:Technetium / Q000097:blood*; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid
chemical_list: D007098:Imino Acids; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; D013667:Technetium