Successful venomous snakebite neutralization with massive antivenin infusion in a child.
Intravenous antivenin requirements to neutralize venomous snake bites can be appropriately calculated based on accurate estimations of injury severity, and/or safely titrated if systemic symptoms are present. This report describes a case in a child given 13 10-ml vials of crotalidae antivenin before and during transfer, and tetanus prophylaxis, cephalosporin (200 mg IV q 6 h), and the titration of 62 additional 10-ml vials of antivenin within 14 hours, based on the child's response to therapy. By the tenth day all symptoms had resolved.
D000997:Antivenins / Q000008:administration & dosage* / Q000009:adverse effects; D002675:Child, Preschool; D003435:Crotalid Venoms; D004890:Erythema / Q000209:etiology; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D012713:Serum Sickness / Q000209:etiology; D012909:Snake Bites / Q000628:therapy*
D000997:Antivenins; D003435:Crotalid Venoms