Effects of a massive single oral dose of oestradiol valerate in a young woman.
Effects of a massive single oral dose of oestradiol valerate were studied in a young woman. A slight increase in serum triglyceride and phospholipid concentrations was seen soon after the oestrogen administration. A marked rise in the serum cortisol concentration was evidently caused by psychic stress on the patient. The EEG examined on the first day after oestrogen administration showed findings typical of subcortical disturbance. One week later the EEG was normal. The low toxicity and slight side effects of a large overdosage of oestradiol valerate by month are worth noting.
D000284:Administration, Oral; D000328:Adult; D002784:Cholesterol / Q000097:blood; D004958:Estradiol / Q000031:analogs & derivatives* / Q000097:blood / Q000506:poisoning; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D010743:Phospholipids / Q000097:blood; D013406:Suicide, Attempted; D014280:Triglycerides / Q000097:blood
D010743:Phospholipids; D014280:Triglycerides; D004958:Estradiol; D002784:Cholesterol; D006854:Hydrocortisone