title: A relation between antibody response and acetylcholinesterase activity in dogs and rabbits infected with Toxocara canis.
abstract: A relation between IgG antibodies and acetylcholinesterase (ACHE) activities was observed in the sera of dogs and rabbits infected with Toxocara canis (T. canis). No antibodies were found in the sera of dogs' fetuses and newborns, more over their ACHE levels were lower than the ones registered in the sera of adult dogs. The ACHE levels of both, the mother dog and the newborn puppies, reached the same level 3 months after delivery. Similar results were obtained in the sera of puppies and adult dogs. In the sera of two rabbits experimentally infected with T. canis, the IgG antibodies were sharply raised 2 weeks after infection and the ACHE levels gradually decreased during the course of this observation. The serum glutamic pyruvic transaminase further tested in these sera gradually increased. From the results obtained, the liver disfunction could be recognized in rabbits but not in dogs, and no relation between antibody and ACHE activities was found neither in the sera of dogs nor rabbits.
mesh_terms: D000110:Acetylcholinesterase / Q000097:blood*; D000375:Aging; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000831:Animals, Newborn; D001196:Ascariasis / Q000276:immunology*; D004285:Dogs; D005333:Fetus / Q000201:enzymology / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis*; D007700:Kinetics; D011817:Rabbits; D014120:Toxocariasis / Q000201:enzymology / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G; D000410:Alanine Transaminase; D000110:Acetylcholinesterase