Classification of tropomyosin components into an alpha-like or a beta-like family by partial peptide mapping.
Tropomyosins can be classified as belonging to an alpha-like or a beta-like family depending on the absence or presence, respectively in their protease-V8 digestion pattern of two peptides with an apparent molecular mass of 21 kDa. Chicken cardiac tropomyosin and the 43 kDa component from gizzard tropomyosin are accordingly classified as alpha-like tropomyosins, while the 33 kDa gizzard tropomyosin component is a beta-like tropomyosin. The 21 kDa peptides have an overall charge which is more positive than that of the intact tropomyosin or any other tropomyosin peptide and probably contain the -NH2 half of the molecule.
D000818:Animals; D001792:Blood Platelets / Q000032:analysis; D002645:Chickens; D004591:Electrophoresis, Polyacrylamide Gel; D005895:Gizzard, Avian / Q000032:analysis; D009132:Muscles / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D010446:Peptide Fragments; D011817:Rabbits; D013552:Swine; D014335:Tropomyosin / Q000145:classification* / Q000302:isolation & purification
D010446:Peptide Fragments; D014335:Tropomyosin