[Disorders of lipid metabolism indices and various aspects of their correction in infectious-toxic lesions of the nervous system in young children].
Lipids, lipoproteins and lipid peroxidation in the blood serum, erythrocyte membranes and CSF were examined in 110 patients (aged 1 month to 3 years) with infectious neurotoxicosis developed in the presence of acute respiratory viral infections, pneumonia and intestinal infection. The results obtained showed a considerable fall in the level of total phospholipids and in their individual fractions in the blood serum and erythrocyte membranes; and their elevation in the CSF as well as increased lipid peroxidation in the blood serum and in the CSF. Among the questions discussed is a possible involvement of upset metabolism of lipids and their peroxides in the pathogenesis of infectious-toxic impairments of the nervous system in children of early age. The questions of their correction with lipostabilizing agents are also reviewed.
D002493:Central Nervous System Diseases / Q000209:etiology* / Q000378:metabolism; D002675:Child, Preschool; D004910:Erythrocyte Membrane / Q000032:analysis; D005260:Female; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000150:complications*; D008055:Lipids / Q000032:analysis*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008563:Membrane Lipids / Q000097:blood; D011014:Pneumonia / Q000150:complications; D012141:Respiratory Tract Infections / Q000150:complications*; D014777:Virus Diseases / Q000150:complications*
D008055:Lipids; D008074:Lipoproteins; D008563:Membrane Lipids
Narusheniia pokazateleĭ obmena lipidov i nekotorye voprosy ikh korektsii pri infektsionno-toksicheskikh porazheniiakh nervnoĭ sistemy u deteĭ rannego vozrasta.