Disulfiram-induced de novo seizures in the absence of ethanol challenge.
The literature on disulfiram-associated seizures is reviewed. A case report of a disulfiram-induced de novo seizure in a 35-year-old man is presented. Possible mechanisms of seizure facilitation are discussed.
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy; D002246:Carbon Disulfide / Q000009:adverse effects; D004221:Disulfiram / Q000009:adverse effects* / Q000627:therapeutic use; D004298:Dopamine / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000139:chemically induced*; D026681:Vitamin B 6 Deficiency / Q000139:chemically induced
D002246:Carbon Disulfide; D004221:Disulfiram; D004298:Dopamine