An unusual cytoplasmic organelle of the perineurium in a case of Duchenne muscular dystrophy.
An unusual cytoplasmic organelle was found in the perineurial sheath of intramuscular nerves in a case of Duchenne muscular dystrophy. It was composed of alternating layers of ribosomes and fibrillar material helically wound around a core of cytoplasm. Comparable organelles have been described in leukemic and other neoplastic cells as well as in the developing cutaneous sensory corpuscle of Grandry.
D001706:Biopsy; D002648:Child; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000294:innervation; D009136:Muscular Dystrophies / Q000473:pathology*; D009940:Organoids / Q000648:ultrastructure*; D010525:Peripheral Nerves / Q000648:ultrastructure*; D012270:Ribosomes / Q000648:ultrastructure