title: Response of dopaminergic neurons in cat to auditory stimuli presented across the sleep-waking cycle.
abstract: The response of dopaminergic neurons of the substantia nigra pars compacta to auditory clicks continuously presented across the sleep-wake cycle was studied in cats. The initial excitatory followed by inhibitory response to the click which occurred during quiet waking diminished as the cat progressed into slow-wave sleep and was absent during REM sleep. Upon awakening from REM sleep, dopamine neurons once again displayed an excitatory/inhibitory response to the clicks, implying that the decrease across the sleep-wake cycle was not attributable to long-term habituation.
mesh_terms: D000818:Animals; D001058:Apomorphine / Q000494:pharmacology; D001306:Auditory Pathways / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D002415:Cats; D004298:Dopamine / Q000502:physiology*; D004594:Electrophysiology; D005260:Female; D009433:Neural Inhibition; D012701:Serotonin / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D013378:Substantia Nigra / Q000502:physiology*
chemical_list: D012701:Serotonin; D001058:Apomorphine; D004298:Dopamine