[Cardiac amyloidosis. Report of 11 autopsy cases and review of the literature].
The authors report 11 cases cardiac amyloidosis discovered on autopsy. The routine examination of the artrial of 20 patients over the age of 60 revealed the presence of these deposits in 10 per cent of cases. Three cases of secondary amyloidosis were discovered with minimal cardiac involvement. There was one case of senile amyloidosis and five cases of primary amyloidosis, two of which were associated with multiple myeloma. The clinical manifestations of these last six cases were cardiac decompensation (congestive in one case) and angina with normal coronary arteries, but involvement of the small vessels. Two cases of anterior pseudo-sequelae are reported and there were 4 cases of disturbances of intraventricular conduction and one case of atrial fibrillation. Amyloid deposits are rarely localized to the heart alone. Associated immunological disorders were present in 3 of the 6 cases. The authors compare this series to a review of the literature.
D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D001344:Autopsy; D009202:Cardiomyopathies / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
Amylose cardiaque. Rapport de 11 cas autopsiés et revue de la littérature.