[Clinical experience with an ampicillin suppository (KS-R1) in bacterial infections in children].
In order to evaluate effectiveness of ABPC suppository (KS-R1) in the treatment of bacterial infections of children, the clinical studies were carried out. KS-R1 was given in rectum to 14 patients in doses of 24.2 approximately 65.8 mg/kg (average 38.5 mg/kg) in 3 approximately 4 divided doses for 3 approximately 8 days (average 4.0 days); 6 with acute tonsillitis, 3 with pneumonia, 1 with otitis media, 4 with UTI. The overall efficacy rate was 100%. Bacterial efficacy was good, i.e. 8 of the 8 strains disappeared. Any clinical side effects and laboratory abnormalities were not observed during treatment. The above results suggested that KS-R1 is a useful antibiotics for pediatric bacterial infections.
D000367:Age Factors; D000667:Ampicillin / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013488:Suppositories; D014552:Urinary Tract Infections / Q000188:drug therapy*
D013488:Suppositories; D000667:Ampicillin