title: 2.5% v 10% phenylephrine in maintaining mydriasis during cataract surgery.
abstract: A 10% viscous solution of phenylephrine hydrochloride was more effective than a 2.5% aqueous solution of phenylephrine hydrochloride in maintaining mydriasis during extracapsular cataract surgery. The pupil area after nucleus expression was 57% larger with the stronger phenylephrine concentration. The difference in pupil area was greater in darkly pigmented irides (114%) than in moderately pigmented (70%) or lightly pigmented irides (12%). Mean BP elevations following phenylephrine administration were not higher in the group receiving the 10% solution than in the group receiving the 2.5% solution. In darkly pigmented irides, a 10% viscous solution of phenylephrine hydrochloride is more effective than a 2.5% concentration in maintaining mydriasis during cataract surgery.
mesh_terms: D000328:Adult; D000368:Aged; D002387:Cataract Extraction; D004106:Dilatation / Q000379:methods; D006801:Humans; D007430:Intraoperative Care; D007498:Iris; D008875:Middle Aged; D010656:Phenylephrine / Q000008:administration & dosage*; D010858:Pigmentation; D011680:Pupil / Q000187:drug effects*
chemical_list: D010656:Phenylephrine