[Surgical correction of interventricular communication with pulmonary stenosis in a hemophiliac].
Open heart surgery was performed in a 5 year-old boy with severe hemophilia A and large ventricular septal defect with pulmonary stenosis. High doses of Factor VIIIC superconcentrates delivered as small transfusion volumes allowed the use of extracorporeal circulation with heparin. Transfusions began 5 hours before surgery and were stopped 21 days later. No adverse reaction was observed. Thus major surgery is possible in severe hemophiliacs provided strict rules for replacement therapy are followed.
D002675:Child, Preschool; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications; D006488:Hemostasis, Surgical; D006801:Humans; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000150:complications / Q000601:surgery*
Correction chirurgicale d'une communication interventriculaire avec sténose pulmonaire chez un hémophile.