Primary aortitis in childhood.
The case of a 5-year-old boy affected by autoimmune aortitis is reported. The onset was acute, the progression rapid. Hypertension, absence of right radial pulse, elevated ESRand immune globulin levels, cellular and humoral immunity against blood vessel wall were observed. The tests suggested an autoimmune origin of the aortitis. On immunosuppressive treatment the signs of activity disappeared and the condition improved and after captopril treatment the blood pressure decreased.
D000917:Antibody Formation; D001025:Aortitis / Q000188:drug therapy / Q000276:immunology*; D001027:Aortography; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000276:immunology; D002464:Cell Migration Inhibition; D002675:Child, Preschool; D002699:Chlorambucil / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008297:Male
D002699:Chlorambucil; D003907:Dexamethasone