Cystic hygroma and hydrops fetalis in a fetus with trisomy 13.
We report a case of trisomy 13 with cystic hygroma and generalized hydrops fetalis diagnosed prenatally by routine ultrasound prior to genetic amniocentesis in a 34-year-old woman. Although fetal cystic hygroma is usually associated with a 45,X karyotype, this and other previous reports suggest that it may be seen in association with other chromosomal and nonchromosomal abnormalities as well. Thus, a diagnosis of Turner Syndrome should not be made on the basis of a cystic hygroma observed by prenatal sonography alone.
D000328:Adult; D002901:Chromosomes, Human, 13-15; D004487:Edema / Q000235:genetics*; D005260:Female; D005315:Fetal Diseases / Q000235:genetics*; D006801:Humans; D008202:Lymphangioma / Q000235:genetics*; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014314:Trisomy; D014463:Ultrasonography