The effect of acute nicotine administration on plasma levels of the thyroid hormones and corticosterone in the rat.
The effects of a single intraperitoneal injection of nicotine hydrogen tartrate (200 micrograms/kg) on the plasma levels of thyroxine, triiodothyronine and corticosterone were monitored over a 24 hour period. Nicotine did not alter the plasma levels of either of the thyroid hormones but did produce a significant increase in plasma corticosterone, an effect which peaked at 20 min post-injection and lasted for 45 min.
D000818:Animals; D003345:Corticosterone / Q000097:blood*; D008297:Male; D009538:Nicotine / Q000008:administration & dosage*; D051381:Rats; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
D013963:Thyroid Hormones; D014284:Triiodothyronine; D009538:Nicotine; D013974:Thyroxine; D003345:Corticosterone