Development and in vivo testing of a chronic percutaneous prosthesis.
Significant progress has been made in the development of a percutaneous energy transmission system (PETS) designed to provide energy to intracorporeally implanted blood pumps for up to 2 years. The mean survival of our six most recent PETS implantations was 351 +/- 33 days. Four of these were explanted electively after a full year of implantation. Sinus formation around each prosthesis was limited by a biomaterial seal at the sinus termination point. The results support the hypothesis that collagen inhibits epidermal downgrowth. Continued development of systems based on this hypothesis is desirable.
D000818:Animals; D001672:Biocompatible Materials; D062109:Dermatologic Surgical Procedures; D004735:Energy Transfer; D005260:Female; D005402:Fistula / Q000517:prevention & control; D007239:Infections; D019736:Prostheses and Implants; D012871:Skin Diseases / Q000517:prevention & control; D013552:Swine
D001672:Biocompatible Materials