[Seasonal features of the excretory function of the liver in the presence of tetracycline damage and correction of the disorders with antioxidants].
It was shown on pubertal albino rats that the intensity of excretion with the bile of radioactive Bengal rose was different at different seasons: the maximum and minimum levels were observed in winter and summer, respectively. When the liver was affected with tetracycline, this process was suppressed especially in summer. The use of antioxidants, such as tocopherol acetate in combination with sodium selenite promoted the recovery of liver excretion function in winter, spring and autumn. In summer, the recovery was only partial.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D056486:Chemical and Drug Induced Liver Injury; D008099:Liver / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D051381:Rats; D012395:Rose Bengal; D012621:Seasons; D020887:Selenious Acid; D012643:Selenium / Q000627:therapeutic use*; D013752:Tetracycline / Q000037:antagonists & inhibitors*; D014810:Vitamin E / Q000627:therapeutic use*
D014810:Vitamin E; D012395:Rose Bengal; D020887:Selenious Acid; D013752:Tetracycline; D012643:Selenium
Sezonnye osobennosti ékskretornoĭ funktsii pechni pri tetratsiklinovykh porazheniiakh i korrektsiia narusheniĭ antioksidantami.