[Regeneration of the peripheral nerves in the lumen of implanted vessels].
Regeneration of the rat peripheral nerve in the lumen of implanted aorta was examined over 4 months. The nerve invaded the vessel with its entire trunk and went out of the distal vessel to the adjacent muscles. Inflammatory infiltrations were observed only outside the implant. Only insignificant number of inflammatory elements were inside the lumen. These conditions favored good regeneration of the nerve without forming a neuroma at the end of the cut nerve. The regenerating myelinized fibers formed spiral-like or bush-like terminals on muscle fibers. The model of directed regeneration of the peripheral nerves in the vascular lumen holds promise for rapid and accurate reinnervation of tissues and organs.
D000818:Animals; D001013:Aorta, Thoracic / Q000637:transplantation*; D002454:Cell Differentiation; D009132:Muscles / Q000166:cytology / Q000294:innervation; D009416:Nerve Regeneration; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000166:cytology / Q000502:physiology*
Regeneratsiia perifericheskikh nervov v prosvete implantirovannykh sosudov.