title: Estrogen accelerates the recovery of the lordosis response after its exhaustion induced by cervical probing.
abstract: Repetitive flank-perineum palpation combined with probing the vaginal cervix in ovariectomized hormonally untreated rats elicited a mean of 4.2 +/- 0.2 (SEM) successive lordosis responses before the response was exhausted. Two days after a single injection of estradiol benzoate (100 micrograms/kg body wt) in ovariectomized rats, a significantly greater number (7.8 +/- 0.2) of lordosis responses could be elicited before the response was exhausted (P less than 0.01). After this exhaustion, recovery of lordosis responsiveness to this stimulation occurred significantly earlier in the estrogen-treated rats (6 hr) than in the oil-treated rats (60 hr) (P less than 0.01). Several possible mechanisms mediating these effects are proposed.
mesh_terms: D000818:Animals; D002369:Castration; D002584:Cervix Uteri / Q000502:physiology; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D010053:Ovary / Q000502:physiology; D010812:Physical Stimulation; D011187:Posture; D051381:Rats; D011919:Rats, Inbred Strains; D012018:Reflex / Q000502:physiology; D012726:Sexual Behavior, Animal / Q000187:drug effects* / Q000502:physiology
chemical_list: D004958:Estradiol