Contact dermatitis to Synthaderm.
Allergic contact dermatitis is described in 2 patients treated with Synthaderm, a polyurethane covering for leg ulcers. One of the patients was patch tested with 3 extractions made from Synthaderm as well as with 5 isocyanate compounds. Her patch tests were negative to both extractions and isocyanates, but positive to Synthaderm samples with different batch numbers and years of production.
D000368:Aged; D001187:Artificial Organs; D003877:Dermatitis, Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000628:therapy; D011140:Polyurethanes / Q000009:adverse effects*; D011446:Prospective Studies
D011140:Polyurethanes; C040003:Synthaderm