Ontogeny of delayed hypersensitivity in young turkeys.
Hypersensitivity to phytohemagglutinin (PHA-P) and Freund's adjuvant containing Mycobacterium tuberculosis was investigated in turkey poults. The kinetics, as indicated by dosage and response time after sensitization, were similar to responses in other birds and laboratory mammals. Newly hatched poults demonstrated delayed hypersensitivity responses, and 2 week old poults exhibited responses of greater magnitude than 8 week old poults. The turkey is proposed as another acceptable species for study of cell-mediated immunity (CMI).
D000367:Age Factors; D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007111:Immunity, Cellular; D010835:Phytohemagglutinins / Q000276:immunology; D014422:Turkeys / Q000276:immunology*
D010835:Phytohemagglutinins