Mesothelioma of the AV node.
A 21-month-old boy died suddenly six months after presenting with heart murmur and second-degree atrioventricular (AV) block. Autopsy revealed a mesothelioma completely replacing the AV node and extending into the central fibrous body. The bundle of His and bundle branches were not involved. Mesothelioma of the AV node is a rare cause of supra-His (AV) block, arrhythmias, and sudden death.
D001283:Atrioventricular Node / Q000473:pathology; D001344:Autopsy; D003645:Death, Sudden / Q000209:etiology*; D004562:Electrocardiography; D006327:Heart Block / Q000209:etiology; D006329:Heart Conduction System; D006337:Heart Murmurs; D006338:Heart Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000473:pathology