[Clinical evaluation of an ampicillin suppository (KS-R1) in pediatrics].
Blood level of ampicillin (ABPC) after the administration of ABPC suppository (KS-R1) reached a peak in 15 approximately 60 minutes with the level of 300 ng/ml at a dose of 1 mg/kg/day. This level was almost the same as that after the intramuscular injection of ABPC, and higher than that after the oral administration of ABPC which were reported. The clinical effective rate (excellent and good) of KS-R1 was more the 95%, and the overall effective rate including bacteriological effect was more than 95%. It is concluded that KS-R1 is a useful drug for the treatment of bacterial infections in pediatric field.
D000367:Age Factors; D000667:Ampicillin / Q000008:administration & dosage* / Q000009:adverse effects / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013488:Suppositories; D014552:Urinary Tract Infections / Q000188:drug therapy*
D013488:Suppositories; D000667:Ampicillin