Unilateral adrenal hemorrhage after chronic nonsteroidal anti-inflammatory drug use.
Nonsteroidal anti-inflammatory drugs, useful in the treatment of a wide variety of major arthritic conditions, have hemorrhagic side effects. We describe a patient receiving long-term naproxen (Naprosyn) therapy in whom unilateral spontaneous adrenal hemorrhage developed. Radiologic and pathologic verifications are included, and a hypothesis of pathogenesis is proposed.
D000307:Adrenal Gland Diseases / Q000139:chemically induced*; D000368:Aged; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007592:Joint Diseases / Q000188:drug therapy; D008297:Male; D009288:Naproxen / Q000009:adverse effects* / Q000627:therapeutic use
D009288:Naproxen