title: Decrease of lactoferrin concentration in the tears of myotonic muscular dystrophy patients.
abstract: Tears from myotonic muscular dystrophy (MMD) patients and normal controls were analyzed for their tear proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Lactoferrin comprised about 18% of the total tear protein in MMD patients as opposed to about 27% in normals. The albumin content relative to total protein in MMD tears was about 25% while the same value for normals is 13%. The lactoferrin/albumin ratio, was about 0.8 for MMD patients and about 2.1 for normals.
mesh_terms: D004910:Erythrocyte Membrane / Q000032:analysis; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods; D007781:Lactoferrin / Q000032:analysis*; D007782:Lactoglobulins / Q000032:analysis*; D009136:Muscular Dystrophies / Q000378:metabolism*; D012394:Rosaniline Dyes; D013666:Tears / Q000032:analysis*
chemical_list: D007782:Lactoglobulins; D012394:Rosaniline Dyes; D007781:Lactoferrin; C004692:coomassie Brilliant Blue