title: [Toxicodynamic properties of liquids used for cooling high-power turbines. I. Acute, subacute and chronic toxicity].
abstract: Oils IWiOL-3 and OMTI are used to cool the high-power turbines. Their toxicodynamic properties are little known, therefore the studies described herein have been undertaken. The studies did not reveal high acute toxicity, as A-DL50 was found to exceed 15 g/kg of body weight. The simultaneous measurements of cholinesterase activity demonstrated its clear decrease, The studies of subacute toxicity after Lim showed that OMTI after a year's exploitation is the most toxic fluid, as C-LD50 for this compound is 6,21 g/kg of body weight, whereas C-LD50 for the other oils is: 22.449 g/kg of body weight for IW i 02-3-n and 20.93 g/kg of body weight for IWiOL-3-e. Studies of chronic toxicity showed decreased cholinesterase activity and no significant changes in the measurements of certain biochemical and haematological. indices.
mesh_terms: D000208:Acute Disease; D000818:Animals; D002802:Cholinesterases / Q000172:deficiency*; D002908:Chronic Disease; D004353:Drug Evaluation, Preclinical; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008899:Mineral Oil / Q000633:toxicity*; D011210:Power Plants; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D008899:Mineral Oil; D002802:Cholinesterases
vernacular_title: Toksykodynamiczne właściwości cieczy stosowanych do chłodzenia turbin wysokiej mocy. I. Toksyczność ostra, podostra i przewlekła.