title: Isolation of leptospires and demonstration of antibodies in human leptospirosis in Madras, India.
abstract: Among 25 clinically suspected cases of leptospirosis, organisms could be isolated from blood and urine of only 10 cases but demonstrated in 15 cases. Antibody titres at a low level were observed to one or more leptospiral antigens in all 25 cases. Nine of the repeated samples from 12 cases showed a four-fold rise in titre. The highest antibody titres were seen against autumnalis. The predominant clinical picture was of fever, myalgia, conjunctival suffusion and jaundice with renal involvement.
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis; D001769:Blood / Q000382:microbiology; D005260:Female; D006801:Humans; D007194:India; D007919:Leptospira / Q000276:immunology / Q000302:isolation & purification; D007922:Leptospirosis / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D008297:Male; D014556:Urine / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial