title: Hyaluronic acid double helix.
abstract: The hyaluronic acid double helix, contrary to an earlier visualization, probably incorporates extensively hydrogen-bonded chains and is pinned together by carboxyl-carboxylate hydrogen bonds and water bridges. Transient interactions between stiffened chain segments provided by the formation of double-helical loops could give rise to the characteristic viscoelastic properties of hyaluronic acid solutions.
mesh_terms: D002236:Carbohydrate Conformation; D003460:Crystallization; D006820:Hyaluronic Acid; D006860:Hydrogen Bonding; D008433:Mathematics; D008958:Models, Molecular; D014867:Water
chemical_list: D014867:Water; D006820:Hyaluronic Acid