Lymphocyte sub-populations in human cord blood: analysis with monoclonal antibodies.
Lymphocytes and monocytes in human cord blood have been analysed using a panel of fourteen monoclonal antibodies. Contrary to earlier data based on the sheep erythrocyte rosette assay for T cells, no marked deficit in T cells was found in cord as compared with adult blood. The T cells in cord blood had a relatively immature phenotype whereas B cells showed a mature phenotype. The phenotypic differences between adult and cord blood appear minor in relation to the marked functional differences reported by others.
D000911:Antibodies, Monoclonal / Q000276:immunology; D000954:Antigens, Surface / Q000032:analysis; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D008214:Lymphocytes / Q000145:classification* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface