Receptive field characteristics of neurones in striate cortex of newborn lambs and adult sheep.
The properties of cells of the striate visual cortex (V1) have been studied in the normal adult sheep and in new-born lambs without visual experience, the majority of cells in the lamb are orientation specific, but 20% are non-oriented compared to only 3% cells in the adult. In the lamb there was little or no facilitation of binocularly-driven cells by simultaneous stimulation of both receptive fields. Cells which responded only to binocular stimulation of particular disparities ('obligate binocular' cells) were rarely encountered. In the adult, 15% of the sample were obligate binocular cells and a further 28% showed binocular facilitation. Simple and complex receptive fields were found in similar proportions in both new-born lambs and adult sheep. End-stopped cells comprised 17% of the sample in adults but only 2% in the lambs. Direction sensitive cells were found more frequently in the sheep (21% of cells) than in the lamb (4% of cells). It is concluded that facilitatory processes in binocular cells and inhibitory mechanisms generally, seem much less developed in the lamb.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D007839:Functional Laterality; D009474:Neurons / Q000502:physiology*; D009799:Ocular Physiological Phenomena; D010775:Photic Stimulation; D012756:Sheep / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*; D014794:Visual Fields