Ethynyl estradiol content of cervical mucus after administration of oral contraceptive.
It was found by radioimmunoassay that the ethynyl estradiol concentration of the cervical mucus was 8.8 times higher than that of the serum in the first third of the cycle, 14 times higher in the second and 7.3 times higher in the third. The ethynyl estradiol content of the cervical mucus in the middle of the cycle showed a marked increase even when expressed as protein ratio. The accumulation of ethynyl estradiol in the cervical mucus is best demonstrated by the cervical mucus/serum ethynyl estradiol quotient of 9.7 found 12 h after oral administration of the contraceptive Bisecurin.
D000328:Adult; D002582:Cervix Mucus / Q000032:analysis*; D003276:Contraceptives, Oral / Q000494:pharmacology*; D004997:Ethinyl Estradiol / Q000032:analysis*; D005260:Female; D006801:Humans; D011506:Proteins / Q000032:analysis; D013997:Time Factors
D003276:Contraceptives, Oral; D011506:Proteins; D004997:Ethinyl Estradiol