Effect of anti-coagulants on cold-reactive anti-lymphocyte activity in the blood of patients with malaria.
The effect of three different anti-coagulants on the level of cold-reactive anti-lymphocyte activity (ALA) in the peripheral blood (PB) of malarious individuals was assessed to determine if plasma could be substituted for serum in assays designed to characterize ALA. Results show that plasma obtained by treating PB with acid-citrate dextrose or ethylenediamine tetraacetic acid can be used instead of serum in these assays but that plasma obtained from heparin-treated blood cannot.
D000328:Adult; D000925:Anticoagulants / Q000494:pharmacology*; D000961:Antilymphocyte Serum / Q000032:analysis*; D003080:Cold Temperature; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D008288:Malaria / Q000276:immunology*; D008297:Male; D010949:Plasma / Q000276:immunology
D000925:Anticoagulants; D000961:Antilymphocyte Serum; D006493:Heparin