title: In vitro activity of midecamycin, a new macrolide antibiotic.
abstract: Midecamycin, an acetoxy-substituted macrolide antibiotic, was tested against gram-positive and gram-negative bacteria. It inhibited the majority of streptococci, staphylococci, and strains of Haemophilus and Listeria at concentrations of less than 3.1 micrograms/ml. It was less active than erythromycin, and it failed to inhibit erythromycin-resistant isolates.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D007933:Leucomycins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D007933:Leucomycins; C026483:midecamycin