title: Biopsychosocial study of diabetes mellitus.
abstract: Historically the medical literature has made reference to psychogenic factors involved in the onset and course of diabetes mellitus. Today, as the reductionistic psychogenic theories are vanishing, one can envision a multicausal interactive model. This includes factors related to life experience mediated by genetic, neurophysiological, endocrine, immune, and psychological functions. New insights into psychophysiological mechanisms and a pluralistic approach will assist the clinician in a more effective therapeutic management of the illness.
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000150:complications; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D011602:Psychophysiologic Disorders; D011613:Psychotherapy; D013564:Sympathetic Nervous System / Q000502:physiology