Fatal soft tissue calcification in suckling puppies.
Renal, pulmonary and vascular calcification was observed in 2 suckling puppies. The lesions were similar to those associated with hypervitaminosis D and possibly hypervitaminosis A. It was suspected that high contents of vitamin D and A in the diet of the lactating bitch had elevated the activity of these vitamins in the milk to levels toxic for the suckling puppies.
D000828:Animal Population Groups; D000818:Animals; D000833:Animals, Suckling; D002114:Calcinosis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology* / Q000473:pathology; D004285:Dogs; D007672:Kidney Cortex / Q000473:pathology; D008168:Lung / Q000473:pathology; D008892:Milk; D014801:Vitamin A / Q000009:adverse effects; D014807:Vitamin D / Q000009:adverse effects
D014801:Vitamin A; D014807:Vitamin D