Immobilisation hypercalciuria after limb fractures in children.
Immobilisation hypercalciuria and hypercalcaemia following limb fractures or paralysis is a frequent occurrence in children. Assessment of calcium metabolism should be performed in such patients, since the formation of kidney stones is possible. The beneficial effect of hydrochlorothiazide (HCT) in the prevention of renal stones is most likely due to a reduction of calcium concentration in urine and a significant decrease of crystalluria. Thus, its administration is recommended for children with hypercalciuria following prolonged immobilisation especially due to fracture treatment or paralysis.
D000293:Adolescent; D000367:Age Factors; D002118:Calcium / Q000097:blood / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D005264:Femoral Fractures / Q000150:complications* / Q000652:urine; D005592:Fracture Fixation / Q000009:adverse effects*; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D007669:Kidney Calculi / Q000209:etiology; D008297:Male
D006852:Hydrochlorothiazide; D002118:Calcium