title: Proton magnetic resonance spectra of 17 xi-hydroxy-17 xi-methyl-5 xi-androstane C-3 ketone and C-3 xi alcohol isomers in chloroform-d and pyridine-d5.
abstract: 17 alpha-Hydroxy-17 beta-methyl-5 beta-androstan-3-one,17 beta-methyl-5 alpha-androstane-3 alpha,17 alpha-diol,17 beta-methyl-5 alpha-androstane-3 beta,17 alpha-diol,17 alpha-methyl-5 beta-androstane-3 beta,17 beta-diol,17 beta-methyl-5 beta-androstane-3 alpha,17 alpha-diol and 17 beta-methyl-5 beta-androstane-3 beta,17 alpha-diol were synthesized for the first time. 1H NMR spectra of all four 17 xi-hydroxy/17 xi-methyl C-3 ketones and all eight C-3 alcohols were recorded in chloroform-d and pyridine-d5. Pyridine-induced chemical shifts are discussed. Thin-layer chromatographic data are given.
mesh_terms: D000732:Androstanols; D002725:Chloroform; D002855:Chromatography, Thin Layer; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008968:Molecular Conformation; D011725:Pyridines; D013329:Structure-Activity Relationship
chemical_list: D000732:Androstanols; D011725:Pyridines; D002725:Chloroform; C023666:pyridine