title: [Effectiveness of oxfendazole against Muellerius capillaris (Nematoda: Protostrongylidae) in goats].
abstract: The effectiveness of oxfendazole against the lungworm Muellerius capillaris was studied on a dairy-goat farm. The goats were treated with a single dose of 5 or 10 mg. per kg/bodyweight or with a dose of 5 mg per kg given three times at 48-hours-intervals. Within a week after treatment, the mean larval counts in the faeces were reduced by 95.7, 89.9 and 99.6 per cent respectively compared with the untreated goats. Within twelve weeks after treatment, this proportion was markedly reduced in the animals treated with a single dose of 5 or 10 mg per kg (to 41.9 and 73.0 per cent respectively), though in the group given three doses the proportion was still 95.1 per cent. Because of the marked temporary decrease of the larval counts shortly after treatment with doses which had none if any lethal effect on adult worms, it can be concluded that it is essential to continue faecal examination for several weeks or months before defining the effectiveness of an anthelmintic against M. capillaris.
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000008:administration & dosage*; D001562:Benzimidazoles / Q000008:administration & dosage*; D005243:Feces / Q000469:parasitology; D005260:Female; D006041:Goats / Q000469:parasitology*; D007814:Larva; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000969:Antinematodal Agents; D001562:Benzimidazoles; C011030:oxfendazole
vernacular_title: De effectiviteit van oxfendazole tegen Muellerius capillaris (Nematoda: Protostrongylidae) bij de geit.