Effect of dexamethasone on plasma catecholamine levels of conscious dogs in haemorrhagic shock.
After 15 mg/kg dexamethasone pretreatment, conscious dogs in haemorrhagic shock demonstrated an augmented plasma noradrenaline increase. Increasing early compensatory adrenergic neuroeffector response could be one of the mechanisms of the protective effect of steroids in shock.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D003907:Dexamethasone / Q000494:pharmacology*; D004285:Dogs; D004837:Epinephrine / Q000097:blood*; D005938:Glucocorticoids / Q000627:therapeutic use; D009638:Norepinephrine / Q000097:blood*; D012771:Shock, Hemorrhagic / Q000097:blood* / Q000188:drug therapy / Q000503:physiopathology
D005938:Glucocorticoids; D003907:Dexamethasone; D009638:Norepinephrine; D004837:Epinephrine