Cytoadherence effects of serum on Ascaris suum infective larvae.
Dead and live Ascaris suum infective larvae were found to adhere to monolayer cultures of mouse peritoneal macrophages following incubation with normal rabbit serum (NRS) or with rabbit anti-A, suum (RAAS). Cell-larval binding was shown to be affected by the numbers of larvae added to cell monolayers and by incubation time. Larval adherence to cell monolayers was dependent upon the concentration of NRS or RAAS in the incubation mixture. Dead larvae were not bound by macrophages in as significant numbers as live larvae after incubation with diluted RAAS. Dead larvae, however, were bound in larger numbers than live larvae after incubation with diluted NRS.
D000268:Adhesiveness; D000818:Animals; D001200:Ascaris / Q000276:immunology / Q000502:physiology*; D001769:Blood; D007106:Immune Sera; D007814:Larva / Q000502:physiology; D008264:Macrophages / Q000469:parasitology*
D007106:Immune Sera