Early involvement of the bronchi in patients with malignant lymphoma.
Fibreoptic bronchoscopy in previously untreated patients with malignant lymphoma provided diagnostic information in 8 of 25 cases with radiological evidence of intrathoracic involvement. There was a marked difference in the pattern of endobronchial involvement between Hodgkin's Disease (HD) and Non Hodgkin's Lymphoma (NHL) which specifically infiltrated the bronchus-associated lymphoid tissue. Bronchoalveolar lavage was abnormal in only one patient with Hodgkin's Disease in whom the presence of many Sternberg-Reed cells suggested occult dissemination of otherwise localised disease.
D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000473:pathology*; D001999:Bronchoscopy; D002452:Cell Count; D005336:Fiber Optic Technology; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008223:Lymphoma / Q000473:pathology*; D008264:Macrophages / Q000473:pathology; D009361:Neoplasm Invasiveness; D011650:Pulmonary Alveoli / Q000473:pathology; D007507:Therapeutic Irrigation; D013997:Time Factors