Tetracycline influence on leukocyte functions.
Two tetracyclines, lymecycline and doxycycline, were investigated with reference to modification of granulocyte function. Both preparations influenced granulocyte adherence, migration, quantitative phagocytosis and induced surface membrane morphological changes. Doxycycline caused more pronounced effects than lymecycline.
D002448:Cell Adhesion / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects; D006801:Humans; D008855:Microscopy, Electron, Scanning; D009504:Neutrophils / Q000187:drug effects* / Q000648:ultrastructure; D010587:Phagocytosis / Q000187:drug effects; D013754:Tetracyclines / Q000494:pharmacology*
D013754:Tetracyclines