[Use of a differential calorimetry method for studying the energy mechanisms of the protective action of anti-ischemic agents].
Differential calorimetry is suggested for quantitative estimation of antiischemic activity of the drugs by determining total energy losses, the critical level of energy losses and permissible times of ischemia of isolated organs. The method allows the unraveling of the mechanisms by which antiischemic resistance of cells and organs is formed with pharmacological means.
D000818:Animals; D002151:Calorimetry / Q000379:methods*; D002152:Calorimetry, Differential Scanning / Q000379:methods*; D002317:Cardiovascular Agents / Q000032:analysis* / Q000627:therapeutic use; D003327:Coronary Disease / Q000188:drug therapy / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects*; D007511:Ischemia / Q000188:drug therapy* / Q000378:metabolism; D007700:Kinetics; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D014810:Vitamin E / Q000032:analysis* / Q000627:therapeutic use
D002317:Cardiovascular Agents; D014810:Vitamin E
Ispol'zovanie metoda differentsial'noĭ kalorimetrii dlia izucheniia énergeticheskikh mekhanizmov zashchitnogo deĭstviia protivoishemicheskikh.