Divalent transition-metal ions (Cu2+ and Zn2+) in the brains of epileptogenic and normal mice.
The concentrations of Cu2+ and Zn2+ in 3 strains of mice were determined spectrophotometrically. The brain of the inborn audiogenic mouse (DBA/2J) contains higher levels of Zn2+ and Cu2+ than those found in the normal mouse (CBA/Ca or Parkes). Small differences in the metallic content in the whole brains of audiogenic and normal mice are accentuated in the hippocampus and the colliculus.
D000161:Acoustic Stimulation; D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000503:physiopathology; D003300:Copper / Q000378:metabolism*; D004827:Epilepsy / Q000378:metabolism*; D005260:Female; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D009474:Neurons / Q000502:physiology; D012016:Reference Values; D012640:Seizures / Q000378:metabolism; D013045:Species Specificity; D015032:Zinc / Q000378:metabolism*
D003300:Copper; D015032:Zinc