A follow-up study on familial polyposis coli in black patients.
We have updated our experience concerning eight families (24 patients) with FPC, 11 of whom had FPC with carcinoma and 13, FPC only. The importance of biopsy to prove the presence of an adenoma (tubular, villous or tubulovillous) was emphasized. Although we prefer total colectomy with ileorectal anastomosis as definitive treatment, total proctocolectomy also has been recommended. The value of careful follow-up examination to detect carcinoma in the retained rectal segment and the periampullary region has been stressed. No racial differences were noted.
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000293:Adolescent; D000328:Adult; D001741:Black or African American; D001706:Biopsy; D003106:Colon / Q000473:pathology; D003111:Colonic Polyps / Q000235:genetics* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000235:genetics; D012007:Rectum / Q000473:pathology; D012306:Risk