Spectrophotometric assay for the detection of antibodies to DNA.
A spectrophotometric assay for the detection of anti-DNA antibodies in the sera of patients with various connective tissue diseases is described. The sensitivity of the method was compared with hemagglutination and enzyme-linked immunosorbent assay. The method is convenient, specific and suitable for use in clinical laboratories where facilities for radioimmunoassay do not exist.
D000937:Antigen-Antibody Reactions; D001323:Autoantibodies / Q000032:analysis*; D004247:DNA / Q000276:immunology*; D006801:Humans; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*
D001323:Autoantibodies; D004247:DNA