Effect of intralipid on total and high-density lipoprotein cholesterol levels in newborns and infants.
Even in very small premature infants (less than 1,000 g) intravenous feeding with Intralipid results in an elevation of total and a fall of high-density lipoprotein (HDL) cholesterol levels. If oral feeding occurs while Intralipid is given, HDL cholesterol levels rise again. A positive correlation was found between levels of total cholesterol and the amount of fat administered. A negative relationship was evident between the level of total cholesterol and that of HDL and between the latter and the amount of fat consumed.
D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL; D005217:Fat Emulsions, Intravenous / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male
D008076:Cholesterol, HDL; D005217:Fat Emulsions, Intravenous; D008075:Lipoproteins, HDL; D002784:Cholesterol