title: Localised (circumscribed) nodular synovitis (histiocytic xanthogranuloma).
abstract: Localised nodular synovitis is a benign tumour which originates from the synovia. The circumscribed nodules are characterised by multinucleated giant cells associated with the proliferation of histiocytes. There is a histiogenetic relationship to the diffuse, heavily pigmented, villo-nodular form. The treatment consists in excising the complete nodule.
mesh_terms: D000328:Adult; D005260:Female; D006099:Granuloma / Q000473:pathology / Q000601:surgery; D006644:Histiocytes / Q000473:pathology*; D006801:Humans; D007592:Joint Diseases / Q000601:surgery; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D013585:Synovitis / Q000601:surgery*; D013586:Synovitis, Pigmented Villonodular / Q000473:pathology / Q000601:surgery*; D014973:Xanthomatosis / Q000473:pathology / Q000601:surgery