Treatment with praziquantel in a patient with schistosomiasis and chronic renal failure.
The pharmacokinetics of praziquantel in a uraemic patient, infected with Schistosoma haematobium, undergoing haemodialysis, was studied by repeated analyses of serum, urine and dialysis fluid. The results indicate the possibility of treating advanced cases of infection with S. haematobium with the normally recommended doses.
D000328:Adult; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000378:metabolism* / Q000628:therapy; D007700:Kinetics; D008297:Male; D011223:Praziquantel / Q000378:metabolism / Q000627:therapeutic use*; D006435:Renal Dialysis; D012548:Schistosoma haematobium; D012552:Schistosomiasis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism
D007546:Isoquinolines; D011223:Praziquantel