[Determination of cefoxitin serum and tissue levels. Perioperative antibiotic prevention in hand surgery in interventions in a bloodless field].
In 63 patients, who underwent handsurgery under tourniquet ischemia, 2 g of Cefoxitin were given i.v. The antibiotic levels in tissue and serum at different times were obtained using biological assay. The results area compared with cefoxitin-concentrations of samples from abdominal surgery. By means of regression-analysis the tissue-serumquotient is defined as the relation of function to the time. The model-character of the conditions unter tourniquet ischemia is described.
D000273:Adipose Tissue / Q000378:metabolism; D001682:Biological Availability; D002349:Carpal Tunnel Syndrome / Q000601:surgery*; D002440:Cefoxitin / Q000097:blood* / Q000627:therapeutic use; D004387:Dupuytren Contracture / Q000601:surgery*; D006801:Humans; D009132:Muscles / Q000378:metabolism; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication
D002440:Cefoxitin
Bestimmung der Cefoxitin-Serum- und Gewebespiegel. Perioperative Antibiotika-Prophylaxe in der Handchirurgie bei Eingriffen in Blutleere.