title: Serum estrogen concentrations during postnatal development in male pigs.
abstract: Serum concentrations of estrone (E1), estradiol (E2), estrone sulfate (E1S), and testosterone (T) were quantified in male pigs at 10 ages from 2 weeks to 2 years. Changes in the concentrations of all four of these hormones were characterized by elevated amounts during neonatal development (1 to 3 weeks of age), a nadir for concentration of each hormone between 1 and 3 months of age, an increase during pubertal development with maximal concentrations at 8 months of age, and no further change by 2 years of age. E1S was predominant of the three estrogens at all age groups with mean concentrations that ranged from 2 to 33 ng/ml. E1 was present in higher concentrations during neonatal development than E2, whereas the reverse situation was observed after 4 months of age. Observations from the present study indicate that early neonatal and pubertal development in male pigs are associated with elevated serum estrogen concentrations.
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000097:blood*; D004970:Estrone / Q000031:analogs & derivatives / Q000097:blood; D008297:Male; D011336:Probability; D013552:Swine / Q000097:blood*; D013739:Testosterone / Q000097:blood
chemical_list: D004967:Estrogens; D004970:Estrone; D013739:Testosterone; D004958:Estradiol; C017296:estrone sulfate