title: Partial finger loss: an indicator of severe connective tissue disease with overlap features.
abstract: Six patients are described with partial finger loss due to severe Raynaud's syndrome. In all cases the vascular changes were an early feature of a connective tissue disease with overlap features. It was a poor prognostic feature often heralding severe multisystem involvement with life threatening and on one occasion fatal consequences.
mesh_terms: D000328:Adult; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D005260:Female; D005385:Fingers / Q000098:blood supply; D006801:Humans; D007511:Ischemia / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000175:diagnosis*