[Teratogenic effect of anticonvulsants with special emphasis on the fetal hydantoin syndrome].
A six-year-old child, whose mother had been taking Hydanphen tablets for 14 years, is presented. The child had a harelip and some other symptoms of the fetal hydantion syndrome. The mother became pregnant again, no abortion was advised, and she gave birth to a healthy child. A possible teratogenic effect of anticonvulsants is discussed.
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis*; D000328:Adult; D002648:Child; D002968:Clavicle / Q000002:abnormalities; D002971:Cleft Lip / Q000139:chemically induced*; D005145:Face / Q000002:abnormalities*; D005260:Female; D005333:Fetus / Q000187:drug effects; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects*; D011247:Pregnancy; D013577:Syndrome
D010672:Phenytoin
Teratogeno djelovanje antikonvulziva s posebnim osvrtom na fetalni hidantoinski sindrom.