Serologic markers of hepatitis B and A infections in the healthy population.
The prevalence of the serologic markers of hepatitis B virus (HBV) and of antibodies to hepatitis A virus (HAV) were determined by radioimmunoassay in 200 healthy subjects. One hundred and seven persons (53.5%) were positive for at least one marker of HBV. The prevalence of each marker was: HBsAg - 9.0%, anti-HBs alone - 2.0%, anti-HBc alone - 2.5%, anti-HBs and anti-HBc - 29.0%, HBsAg and anti-HBc - 11.0%. Evidence of a previous infection with HAV was found in 155 persons (77.5%); three of them had anti-HAV type IgM. These findings indicate that in the area investigated HAV infection is endemic, and HBV infection has a trend towards endemicity.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology*; D035922:Hepatitis A Antibodies; D006509:Hepatitis B / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006512:Hepatitis B Core Antigens / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis* / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D011247:Pregnancy; D011863:Radioimmunoassay; D012383:Romania
D000914:Antibodies, Viral; D035922:Hepatitis A Antibodies; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens