title: [Various current problems in clinical psychopharmacology].
abstract: On the basis of author's findings and those reported in the literature, advances and shortcomings of contemporary psychopharmacology are analyzed. Despite the fact that psychopharmacotherapy, in comparison with the previous methods, is a principally new stage in the treatment of psychic diseases; in its present form it is incapable of meeting all the requirements of psychiatric practice (a tendency toward chronicity characteristic of psychic diseases has not been overcome, some patients still continue to display resistance to known psychotropic agents, aggravation of some psychopathologic disturbances and the development of persistent incurable conditions can be observed in the course of psychopharmacotherapy). In view of the fact that with the currently available drugs and their medicinal forms, psychopharmacology as a method of therapy is at the outer limits of its possibilities, ways of its optimization are discussed. General guidelines for its further development, most promising in terms of their realization and scientific validation, are identified.
mesh_terms: D000553:Ambulatory Care; D001883:Borderline Personality Disorder / Q000188:drug therapy; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D011600:Psychopharmacology / Q000639:trends*; D011618:Psychotic Disorders / Q000188:drug therapy; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs
vernacular_title: Nekotorye aktual'nye problemy klinicheskoĭ psikhofarmakologii.