title: Brain-derived fibroblast growth factor: a study of its inactivation.
abstract: Brain fibroblast growth factor has been identified as a component of myelin basic protein. Its activity is destroyed when treated with a variety of solvents including dilute acid, organic solvents and solutions of guanidine hydrochloride. These conditions do not alter the encephalitogenic properties of myelin basic protein.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D002460:Cell Line; D005346:Fibroblast Growth Factors / Q000037:antagonists & inhibitors / Q000302:isolation & purification*; D006146:Guanidines / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D051379:Mice; D008807:Mice, Inbred BALB C; D012997:Solvents / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism
chemical_list: D006146:Guanidines; D012997:Solvents; D005346:Fibroblast Growth Factors; D013936:Thymidine