Synthesis of 73As-radiolabelled arsenobetaine and arsenocholine for metabolic studies and their fate and distribution in laboratory animals.
73As-labelled arsenobetaine and arsenocholine have been synthesized in mg scales in this laboratory. Specific radioactivities in the range of 100 muCi (3.7 MBq) 73As/mg As have been employed. Further purification of the synthesized compounds has been performed by ion exchange chromatography.
D000818:Animals; D001151:Arsenic / Q000378:metabolism; D001152:Arsenicals / Q000138:chemical synthesis*; D003445:Crustacea / Q000378:metabolism; D005399:Fishes / Q000378:metabolism; D005506:Food Contamination; D007553:Isotope Labeling / Q000379:methods; D008297:Male; D011868:Radioisotopes; D051381:Rats
D001152:Arsenicals; D011868:Radioisotopes; C039920:arsenocholine; D001151:Arsenic; C038992:arsenobetaine