title: A symptom based approach to the diagnosis of schizophrenia.
abstract: This study reviews the attempts of Carpenter et al to develop valid diagnostic criteria of schizophrenia by means of a flexible 12 point system of signs and symptoms based on the IPSS. The authors applied the 12-point system to 67 inpatients and obtained different levels of certainty in identifying proportions of schizophrenic and non-schizophrenic patients: 80% of clinically diagnosed schizophrenic patients obtained 5 or more points. Kappa statistics revealed a 0.59 proportion of agreement in excess to chance between clinical and experimental diagnosis of schizophrenia, indicating the clinical usefulness of the 12 point system.
mesh_terms: D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology