title: [Clinical aspects, pathomorphology and histokinetics in experimental Eimeria acervulina infection in chickens].
abstract: Experiments were carried out with birds experimentally infected with Eimeria acervulina. It was found that this causative agent was responsible for catarrhal to hemorrhagic enteritis, however, the feces did not contain blood despite their becoming watery. In the duodenum it was shown to accomplish schizogony three times: the first schizogony took place up to the 72nd hour, the second one--up to the 120th hour, and the third one--up to the 168 th hour. On the other hand, gametogony started at the 168 th hr. Most severe lesions in the mucosa were found on the 7th-8th day following infection. They coincided in time with the third generation of schizonts and the gametogony. The alteration processes in the mucous membrane affected the villi to a larger extent than the propria mucosae. Villi regeneration proceeded from the 9 th to the 12 th day. The prepatent period lasted 144 hours. Macrophages were not found to carry the sporozoites to the glands. Dystrophic and necrobiotic changes in the viscera predominated over the proliferation processes, and this made it reasonable to believe that the basic moment in the pathogenesis of the disease was the mechanical destruction of the epithelial cells of the villi as well as the adsorption of toxic products from the decomposition of the necrotic cell mass in the intestinal lumen. Eimeria acervulina was said to produce pathogenic, but not lethal effects.
mesh_terms: D000818:Animals; D002645:Chickens; D003048:Coccidiosis / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004751:Enteritis / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D006651:Histocytochemistry; D007413:Intestinal Mucosa / Q000473:pathology; D007700:Kinetics; D011201:Poultry Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D013997:Time Factors
vernacular_title: Vŭrkhu klinikata, patomorfologiiata i khistokinezata pri pileta, eksperimentalno zarazeni s Eimeria acervulina.