Modifications in apoprotein C composition of very low density lipoproteins in type IV hyperlipoproteinemic subjects after dietetic triglyceridemia reduction.
Variations in peptide composition of apoprotein C from very low density lipoproteins were studied in 10 type IV hyperlipoproteinemics, before and after triglyceridemia normalization through appropriate diet. The subjects were sensitive to carbohydrates or alcohol : a reduction or elimination of the inducing nutrient led to a decrease in serum triacylglycerol levels, correlated with an increase in the proportion of apo CII and a decrease in the proportion of apo CIII1. Apo CIII2 was not affected. This led to an increased ratio, apo CII/apo CIII1. The percentage of variation of different lipid (triacylglycerols and cholesterol) and protein (apoproteins CII, CIII2) parameters were also studied.
D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D001056:Apolipoproteins C; D006801:Humans; D006953:Hyperlipoproteinemia Type IV / Q000097:blood* / Q000178:diet therapy; D008079:Lipoproteins, VLDL / Q000097:blood*; D014280:Triglycerides / Q000097:blood
D001053:Apolipoproteins; D001056:Apolipoproteins C; D008079:Lipoproteins, VLDL; D014280:Triglycerides