title: The complementary roles of brain scintigraphy and computed tomography in multiple sclerosis.
abstract: Cerebral computed tomography, with and without iodinated contrast, revealed the appearance and evolution of lesions in a 32-year-old man with multiple sclerosis. Two areas were enhanced with contrast, with one showing a mild mass effect and rim of enhancement. Serial brain scintigraphy using technetium-99m glucoheptonate, following the computed tomography, showed the appearance and regression of corresponding regions of increased uptake. Computed tomography one day prior to brain scintigraphy failed to demonstrate a region of increased accumulation of radiotracer. One week later, however, evidence of a corresponding unenhanced defect was noted on computed tomography. Clinical correlation is given additionally.
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis*; D015609:Organotechnetium Compounds; D011856:Radiographic Image Enhancement; D011877:Radionuclide Imaging; D013400:Sugar Acids; D013667:Technetium; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D013400:Sugar Acids; D013667:Technetium; C100014:technetium Tc 99m gluceptate