Carbohydrate inhibition of chlamydial infectivity.
The effects of exogenous carbohydrates on chlamydial infectivity were tested. It was shown that the addition of certain carbohydrates reduced the infectivity of Chlamydia psittaci in cell culture. The greatest inhibitory effects were observed by monosaccharides, disaccharides and trisaccharides, respectively. The addition of ATP, but not AMP, enhanced the inhibitory effect.
D000249:Adenosine Monophosphate / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D002241:Carbohydrates / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D002690:Chlamydia Infections / Q000503:physiopathology*; D002691:Chlamydophila psittaci; D007739:L Cells; D051379:Mice
D002241:Carbohydrates; D000249:Adenosine Monophosphate; D000255:Adenosine Triphosphate