title: Expanded operational concept of high risk groups and its role in standard setting.
abstract: The role of the knowledge of high risk groups in the standard-setting process is examined. The overall conclusion is that many potential high risk segments of the population have not been studied adequately and that this deficiency in our knowledge markedly reduces the ability of decision makers to derive appropriate regulatory decisions by either ignoring the potential health effects or applying potentially excessive and expensive safety factors.
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D000818:Animals; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D004285:Dogs; D006801:Humans; D051381:Rats; D012015:Reference Standards; D012306:Risk; D012756:Sheep
chemical_list: D000393:Air Pollutants