The value of combined alpha- and beta-adrenoceptor blockade in angina pectoris.
The alpha- and beta-blocking effects of labetalol are such that during and following exercise the haemodynamic benefits of beta-blockade outweigh the unfavourable effects, because the latter are diminished by the concomitant minor degree of alpha-blockade.
D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D004983:Ethanolamines / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007741:Labetalol / Q000627:therapeutic use*
D004983:Ethanolamines; D007741:Labetalol