The three dimensional structure of sheep liver 6-phosphogluconate dehydrogenase at 2.6 A resolution.
The three-dimensional structure of sheep liver 6-phosphogluconate dehydrogenase has been determined at 2.6 A resolution by X-ray crystallographic studies. The amino acid sequence of the enzyme is now known and can be fitted to a modified electron density map. Use of 6 A electron density maps and the results of chemical modification experiments allows description of the active site and identification of residues which may be implicated in the binding of co-enzyme and substrate.
D000818:Animals; D001665:Binding Sites; D004583:Electrons; D008099:Liver / Q000201:enzymology*; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011487:Protein Conformation; D012756:Sheep
D010734:Phosphogluconate Dehydrogenase