title: [Multiple tumors in the upper aerodigestive tract--a retrospective study].
abstract: The authors observe an increasing incidence of multiple primary neoplasms in the upper aerodigestive tract. Out of 1231 patients with neoplasms, 110 (= 8.9%) developed another tumour. Following oral cavity tumours the incidence of second tumours was twice as high as in other localities. Privileged site of second tumours following cancer of the larynx is the lung, after oral cavity neoplasms the hypopharynx and larynx. The mean interval between first and secondary neoplasms was 4.4 years. In tumour follow-up therapy it is recommended to look not only for relapses and metastases but also for second tumours.
mesh_terms: D005860:Germany, West; D006801:Humans; D007013:Hypopharynx; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D008175:Lung Neoplasms / Q000453:epidemiology*; D009062:Mouth Neoplasms / Q000453:epidemiology*; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology* / Q000401:mortality; D009960:Oropharynx; D010610:Pharyngeal Neoplasms / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies
vernacular_title: Mehrfachtumoren im oberen Aerodigestivtrakt--eine retrospektive Studie.