Exocrine pancreatic function in the elderly.
We studied pancreatic bicarbonate and enzyme output in response to a continuous intravenous infusion of secretin, 1 CU/kg X h, and cerulein, 100 ng/kg X h, in 25 elderly subjects and in 30 young controls. Almost all elderly persons had pancreatic outputs within the range of controls. Only 3 aged individuals showed diminished enzyme output, but the reduction was very slight. We conclude that exocrine pancreatic function is not significantly influenced by aging.
D000328:Adult; D000368:Aged; D000375:Aging; D001639:Bicarbonates / Q000378:metabolism; D002918:Chymotrypsin / Q000378:metabolism; D005260:Female; D006801:Humans; D008049:Lipase / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000201:enzymology / Q000502:physiology*; D012636:Secretory Rate; D014357:Trypsin / Q000378:metabolism
D001639:Bicarbonates; D008049:Lipase; D002918:Chymotrypsin; D014357:Trypsin