title: [Assay of 2-phenylbutyric acid in plasma with gas and liquid chromatography].
abstract: Two chromatographic methods which allow the measurement of 2-phenylbutyric acid in serum are described: a gas chromatographic, after silylation, and a reversed-phase high-performance liquid chromatographic. The liquid chromatography with a fluorescent detection, after derivatization by 4-bromomethyl-7-methoxycoumarin, is ten times more sensitive than gas chromatography and 50 ng/ml can be measured in biological liquids.
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D002853:Chromatography, Liquid / Q000379:methods; D006801:Humans; D010654:Phenylbutyrates / Q000097:blood*
chemical_list: D010654:Phenylbutyrates; C039714:2-phenylbutyric acid
vernacular_title: Dosage de l'acide phenyl-2 butyrique dans le plasma par chromatographie gazeuse et chromatographie liquide.