title: [Changes in the contractile activity of the left heart ventricle and blood content of free fatty acids during acute focal myocardial ischemia in rabbits at different times of the day].
abstract: Left-ventricular contractility and arterial blood levels of free fatty acids were studied experimentally in rabbits with acute focal myocardial ischemia at different hours of the day (12 a. m., 6 p. m., 12 p. m.). All parameters were measured before a myocardial acute-ischemia focus was created, and 15, 20 and 40 minutes after coronary artery ligation. Heart contractility and blood free fatty acid levels were shown to vary throughout the day. In acute focal myocardial ischemia, these parameters also show different patterns of variation. A relationship was demonstrated between the pattern of changes in some contractility indices under acute focal ischemia and blood baseline levels of free fatty acids, which was particularly manifest at 12 p. m., and grew very weak at 12 a. m.
mesh_terms: D000208:Acute Disease; D000818:Animals; D002940:Circadian Rhythm; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology*; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D009200:Myocardial Contraction; D011817:Rabbits
chemical_list: D005230:Fatty Acids, Nonesterified
vernacular_title: Izmenenie sokratitel'noĭ aktivnosti levogo zheludochka serdtsa i soderzhaniia svobodnykh zhirnykh kislot v krovi pri ostroĭ ochagovoĭ ishemii miokarda u krolikov v raznoe vremia sutok.