title: Multiple laryngeal papillomatosis requiring laryngectomy.
abstract: Laryngectomy has been performed on two of the 63 cases of laryngeal papillomatosis treated at the Royal National Throat, Nose, and Ear Hospital, London, over 24 years. Their case histories are reported to illustrate the difficulties in managing extremely diffuse and recurrent forms of the disease. Whole organ laryngeal sections of one case are presented. Both patients experienced an improved life-style and fewer hospitalizations following laryngectomy. Although improved microsurgical methods are now available, the search continues for a treatment that will significantly alter the course of the disease.
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery*; D010212:Papilloma / Q000473:pathology / Q000601:surgery*