Responses of unanaesthetised and pentobarbitone-anaesthetised sheep to a lethal dose of succinyldicholine.
A lethal dose of succinyldicholine was administered to 3 unanaesthetised and 4 pentobarbitone-anaesthetised, non-ventilated sheep. When compared to the unanaesthetised sheep, the anaesthetised sheep had smaller increases in arterial and central venous blood pressure, blood glucose and plasma catecholamines. It was concluded that the difference in response between the groups could largely be ascribed to conscious perception of asphyxia in the awake group with resulting fear.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D004837:Epinephrine / Q000097:blood; D009638:Norepinephrine / Q000097:blood; D012756:Sheep / Q000378:metabolism*; D013390:Succinylcholine / Q000494:pharmacology*
D001786:Blood Glucose; D013390:Succinylcholine; D009638:Norepinephrine; D004837:Epinephrine