title: Heparin for lacunar stroke in progression.
abstract: Four patients with mild hemiparesis were treated with heparin for presumed progressing stroke. All worsened to hemiplegia with pure motor deficits and lacunar infarcts despite this medical intervention. Clinical distinction between large artery and small, penetrating vessel thrombotic disease is needed to best evaluate any benefit of anticoagulation for stroke in progression.
mesh_terms: D000328:Adult; D000368:Aged; D002544:Cerebral Infarction / Q000188:drug therapy; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D004341:Drug Evaluation; D004569:Electroencephalography; D005260:Female; D006429:Hemiplegia / Q000188:drug therapy; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D013997:Time Factors
chemical_list: D006493:Heparin