Mast-cell heterogeneity in the rat.
In the rat, O-hydroxy ethyl rutoside derivatives release histamine and serotonin from skin mast-cells, but not from peritoneal mast-cells. These cellular populations do not exhibit identical pharmacological properties.
D000818:Animals; D001201:Ascites; D006636:Histamine Release; D006896:Hydroxyethylrutoside / Q000494:pharmacology*; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012431:Rutin / Q000031:analogs & derivatives*; D012701:Serotonin / Q000378:metabolism; D012867:Skin / Q000166:cytology
D006896:Hydroxyethylrutoside; D012701:Serotonin; D012431:Rutin