Long-acting contraceptive agents: norethisterone esters of monoalkenyl and monoalkynyl acids.
The synthesis of nine new esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) is described, with the esterifying acids bearing an acetylenic or olefinic function in a chain of eight or nine carbon atoms, for evaluation as long-acting contraceptive agents.
D003692:Delayed-Action Preparations; D004952:Esters; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009640:Norethindrone / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013329:Structure-Activity Relationship
D003692:Delayed-Action Preparations; D004952:Esters; D007202:Indicators and Reagents; D009640:Norethindrone