title: Biochemistry of the ageing rat lens. I. Lens wet weight and lens dry weight with respect to sex differences.
abstract: The lens wet weight differed from the age of 136 days: the male lenses were significantly heavier than the female lenses. The dry weight, in percent of the lens wet and dry weight, of the water-soluble proteins decreased and the dry weight of the water-insoluble proteins increased during ageing. At an age of 870 days, when the dry weight curves crossed each other, the lens contains equal amounts of water-soluble and water-insoluble proteins. At the end of the life expectancy, the relation between the water-soluble and water-insoluble moiety was 0.7 for the rat and 3.5 for the bovine lens. The dry weight percent of the water-soluble proteins was lower for the female lens, whereas that of the water-insoluble proteins was higher for the female lens. The male lens, on the contrary, showed a higher percentage of water-soluble and a lower percentage of water-insoluble proteins with increasing age. The ratio R of the dry weight of water-soluble to water-insoluble proteins was, from the age of 429 days, lower for the female lens. During ageing, the proportion of the lens-water was higher for the male lens.
mesh_terms: D000367:Age Factors; D000818:Animals; D002417:Cattle; D003459:Crystallins / Q000032:analysis; D004285:Dogs; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000032:analysis*; D008297:Male; D051379:Mice; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D014867:Water / Q000032:analysis*
chemical_list: D003459:Crystallins; D014867:Water