title: Pyridoxine therapy in patients with renal calcium oxalate calculi.
abstract: In 12 patients with idiopathic calcium oxalate calculi pyridoxine was administered. Within six weeks mean daily oxalic acid excretion decreased from 480 +/- 122 mumol to 336 +/- 83 mumol. Glycolic acid excretion fell from 208 +/- 51 mumol to 153 +/- 26 mumol (normal range: oxalic acid 228-412 mumol/day, glycolic acid 130-290 mumol/day). The reduction of oxalic acid excretion seems to be beneficial in prevention of idiopathic calcium oxalate calculi.
mesh_terms: D002129:Calcium Oxalate / Q000032:analysis; D006016:Glycolates / Q000652:urine; D006801:Humans; D007669:Kidney Calculi / Q000188:drug therapy* / Q000378:metabolism; D010070:Oxalates / Q000652:urine; D019815:Oxalic Acid; D011736:Pyridoxine / Q000627:therapeutic use*
chemical_list: D006016:Glycolates; D010070:Oxalates; C031149:glycolic acid; D002129:Calcium Oxalate; D019815:Oxalic Acid; D011736:Pyridoxine