[Relationship between bovine serum composition and its capacity to stimulate cell culture growth].
A relationship has been studied between the growth-stimulating activity and chemical composition of bovine serum (BS) that is widely used for cell culture growth and virus replication. A direct correlation was shown between the growth-promoting activity of bovine serum, manifested on the model of chick embryo fibroblasts, and the contents of phospholipids, total lipids, proteins, and calcium in this serum. A significant inverse association has also been revealed between the growth-promoting activity of the serum and the amounts of cholesterol and glucose in this.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured / Q000187:drug effects*; D055598:Chemical Phenomena; D002621:Chemistry; D002642:Chick Embryo; D003470:Culture Media / Q000494:pharmacology; D005347:Fibroblasts / Q000187:drug effects; D007106:Immune Sera / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013329:Structure-Activity Relationship
D003470:Culture Media; D007106:Immune Sera
Sviaz' mezhdu sostavom syvorotki krupnogo rogatogo skota i ee sposobnost'iu stimulirovat' rost kletochnykh kul'tur.