Fasting modulates creatine entry into skeletal muscle in the mouse.
[14C]-Creatine entry into skeletal muscle of mice is inhibited by feeding creatine or by fasting. Plasma creatine specific activity after an i.p. injection of [14C]-creatine is decreased by feeding creatine and increased by fasting. These results indicate that creatine enters muscle via a saturable process that is modulated by fasting.
D000818:Animals; D003401:Creatine / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology; D005215:Fasting; D007700:Kinetics; D008297:Male; D051379:Mice; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*
D003401:Creatine