Experimental infection of Nematospiroides dubius in Swiss albino mice. IX. Effect of dose break up on the serum protein patterns.
The present study concerns with the effects of larval inoculation with either a single dose or two or more spaced doses of 200 larvae on the serum protein profiles. No significant difference occurred in the various fractions among the three groups indicating that the total quantity of antigenic stimulation in the most important factor in eliciting such changes, no matter whether the dose is given once or spaced in two or three small doses. Serum protein fractions of Swiss albino mice undergoing experimental infection of Nematospiroides dubius do not tend to rise further due to repeated exposures in comparison to those that received a challenge dose only (1). Hence, experiments were designed to ascertain whether there is any difference in serum protein patterns due to breaking up of the infective dose into two or three spaced doses of N. dubius larvae.
D000818:Animals; D007111:Immunity, Cellular; D007814:Larva; D051379:Mice; D008815:Mice, Inbred Strains; D012709:Serum Albumin / Q000032:analysis*; D012712:Serum Globulins / Q000032:analysis*; D014252:Trichostrongyloidiasis / Q000097:blood*
D012709:Serum Albumin; D012712:Serum Globulins