Effects of various agents on the in vivo "lipoperoxide" content of rat liver and kidney and on the "lipoperoxide" and lipid content of liver slices.
"Lipoperoxide" content increases in rat livers 2h after emetine and glucosamine and 24h after CCl4, cycloheximide, colchicine, emetine and ethionine administration. Renal "lipoperoxides" decrease 24h after glucosamine and 24h and 72h after X-rays. In liver slices thiobarbituric acid values are increased by diethyl maleate, glucosamine and puromycin. Loss in lipid content is accelerated in liver slices by cycloheximide, emetine, FeCl3 but counteracted by colchicine and ethanol.
D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D004640:Emetine / Q000494:pharmacology; D005260:Female; D007668:Kidney / Q000032:analysis / Q000187:drug effects*; D008054:Lipid Peroxides / Q000032:analysis*; D008055:Lipids / Q000032:analysis*; D008099:Liver / Q000032:analysis / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains
D008054:Lipid Peroxides; D008055:Lipids; D003513:Cycloheximide; D004640:Emetine