Detection of metastatic neuroblastoma cells in bone marrow aspirates by formaldehyde induced fluorescence histochemistry.
Metastatic neuroblastoma cells in bone marrow aspirates were examined by the formaldehyde induced fluorescence histochemical method. With this method we could easily identify abnormal cells as metastatic neuroblastoma cells by observing catecholamine green colored fluorescence in their cytoplasma. This formaldehyde induced fluorescence histochemical method is significantly useful for the diagnosis of metastatic neuroblastoma of the bone marrow.
D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination; D002395:Catecholamines / Q000032:analysis; D005557:Formaldehyde; D006651:Histocytochemistry; D006801:Humans; D008856:Microscopy, Fluorescence; D009362:Neoplasm Metastasis; D009447:Neuroblastoma / Q000473:pathology / Q000556:secondary*
D002395:Catecholamines; D005557:Formaldehyde