[Immunogenicity of a conjugate of bovine serum albumin with polyacrylic acid].
The conjugate of bovine serum albumin (BSA) with polyacrylic acid, in contrast to pure BSA and the mixture of BSA with polymer, induces a pronounced primary humoral response. The injection of the conjugate in Freund's complete adjuvant leads to considerable immune response to BSA, 30-40 and 100-130 times more intensive than that produced, respectively, by the injection of the conjugate alone or BSA in the adjuvant.
D000180:Acrylic Resins / Q000138:chemical synthesis / Q000276:immunology*; D000818:Animals; D000906:Antibodies / Q000032:analysis; D000918:Antibody Specificity; D004338:Drug Combinations; D004357:Drug Synergism; D005620:Freund's Adjuvant / Q000494:pharmacology; D007114:Immunization; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012710:Serum Albumin, Bovine / Q000276:immunology*; D013997:Time Factors
D000180:Acrylic Resins; D000906:Antibodies; D004338:Drug Combinations; D012710:Serum Albumin, Bovine; C006903:carbopol 940; D005620:Freund's Adjuvant
Immunogennost' kon"iugata bych'ego syvorotochnogo al'bumina s poliakrilovoĭ kislotoĭ.