title: [Clinical evaluation of an ampicillin suppository (KS-R1) in infections in children].
abstract: The following results were obtained in clinical trials of new ampicillin suppository (KS-R1) in the pediatric infection. Twenty-four patients comprising 15 with respiratory tract infection, 9 with urinary tract infection were received KS-R1 at the dose ranging from 31 mg/kg to 75 mg/kg divided 3 or 4 times a day. The results in the respiratory tract infection were "excellent" in 8 and "good" in 6, and the efficacy rate was 93.3%. The results in the urinary tract infection were "excellent" in 4 and "good" in 3, and the efficacy rate was 77.8%. Diarrhea were observed in 4 patients, and anal pain was observed in 1. But the symptoms were transient. No abnormal laboratory findings were observed.
mesh_terms: D000367:Age Factors; D000667:Ampicillin / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013488:Suppositories; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D013488:Suppositories; D000667:Ampicillin