title: The influence of the nucleus on the regulation of the dCMP deaminase in acetabularia.
abstract: The enzyme activity of dCMP deaminase (EC 3.5.4.12) In Acetabularia mediterranea is substantially increased at the beginning of cyst formation. A similar albeit advanced increase is observed in anucleate cells. The advance in the anucleate cells is not due to non-specific effects of cell surgery since nucleate grafts which are also subjected to surgery exhibit a delayed regulation characteristic for nucleate cells. Moreover, the nuclear effect on the regulation is demonstrated by experiments in which the flow of information from nucleus to cytoplasm is interrupted by treatment with actinomycin D or by tying off the rhizoid for five days. In these cells not only is the time of the increase advanced but also cyst formation is accelerated.
mesh_terms: D002467:Cell Nucleus / Q000502:physiology; D000460:Chlorophyta / Q000166:cytology / Q000201:enzymology / Q000502:physiology*; D003844:DCMP Deaminase / Q000378:metabolism*; D009709:Nucleotide Deaminases / Q000378:metabolism*
chemical_list: D009709:Nucleotide Deaminases; D003844:DCMP Deaminase