title: Corticosteroid abuse--an unusual manifestation of drug dependence.
abstract: A depressed 44-year-old man presented with a 2 1/2-year history of use of a synthetic glucocorticoid (prednisone) as the only psychoactive drug. The pattern of use strongly suggested drug dependence; secondary Cushing's syndrome was noted. We call attention to the potential abuse of neuroendocrine agents and, more specifically, corticosteroid preparations.
mesh_terms: D000328:Adult; D003480:Cushing Syndrome / Q000139:chemically induced*; D003866:Depressive Disorder / Q000188:drug therapy; D006801:Humans; D008297:Male; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D019966:Substance-Related Disorders
chemical_list: D011241:Prednisone