Lack of singlet oxygen formation by photoexcited promazine derivatives in aqueous and ethanolic solutions.
The EPR detection of nitroxide formation and the observation by thin layer chromatography of the specific 1O2 oxidation product of cholesterol, have been used to appreciate singlet oxygen production by promazine and four of its derivatives during irradiation with near-UV light of ethanolic and aqueous solutions. Within the range of sensitivity of the methods, no 1O2 had been detected.
D000075:Acepromazine / Q000528:radiation effects; D002746:Chlorpromazine / Q000528:radiation effects; D002784:Cholesterol / Q000378:metabolism; D010084:Oxidation-Reduction; D010100:Oxygen; D010640:Phenothiazines / Q000528:radiation effects; D010777:Photochemistry; D011395:Promazine / Q000528:radiation effects*; D014273:Triflupromazine / Q000528:radiation effects
D010640:Phenothiazines; D000075:Acepromazine; D002784:Cholesterol; C008393:methopromazine; D011395:Promazine; D014273:Triflupromazine; D010100:Oxygen; D002746:Chlorpromazine