[Antigenic activity and the reactogenicity of a concentrated, purified, UV-inactivated cultured rabies vaccine].
The results of the study of concentrated, purified, UV-inactivated cell-culture rabies vaccine, obtained from strain Vnukovo-22, passage 33-40, in the primary culture of Syrian hamster kidney cells, demonstrated the pronounced antigenic potency of this vaccine: when introduced intramuscularly in 3-4 injections at certain intervals, it induced the production of virus-neutralizing antibodies in high titers. In tests on volunteers the vaccine proved to be nonreactogenic.
D000293:Adolescent; D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000009:adverse effects / Q000276:immunology* / Q000302:isolation & purification; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D007114:Immunization; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D011819:Rabies Vaccines / Q000009:adverse effects / Q000276:immunology* / Q000302:isolation & purification; D011820:Rabies virus / Q000276:immunology; D013997:Time Factors; D014466:Ultraviolet Rays; D014613:Vaccines, Attenuated / Q000009:adverse effects / Q000276:immunology / Q000302:isolation & purification; D014776:Virus Cultivation
D000914:Antibodies, Viral; D000956:Antigens, Viral; D011819:Rabies Vaccines; D014613:Vaccines, Attenuated
Antigennaia aktivnost' i reaktogennost' kontsentrirovannoĭ ochishchennoĭ inaktivirovannoĭ UF-luchami kul'tural'noĭ antirabicheskoĭ vaktsiny.