title: Mechanical valves: a comparative analysis of the Starr-Edwards and Björk-Shiley prostheses.
abstract: Despite the requirement of anticoagulation, mechanical valve prostheses offer the advantage of proven durability. We have compared the long-term results of 467 aortic valve replacements and 342 mitral valve replacements using the Starr-Edwards prosthesis with 110 aortic valve replacements and 105 mitral valve replacements using the Björk-Shiley prosthesis from 1973 through 1977. Improvement in New York Heart Association (NYHA) class was noted in greater than 80% of patients in all four groups. Long-term survival with mean follow-up over 5 years was not significantly different between respective groups. The probability of thromboembolic complications, however, was significantly higher (p less than 0.05) with the Starr-Edwards prosthesis in both the aortic and mitral positions. The probability of valve failure, although low for all groups, was significantly higher (p less than 0.05) in the Björk-Shiley mitral group due to late thrombotic occlusion. Use of the Starr-Edwards and Björk-Shiley prostheses is associated with satisfactory functional improvement and similar long-term survival rate. However, the increased risk of valve failure due to late thrombotic occlusion of the Björk-Shiley prosthesis should be considered when choosing a mechanical mitral prosthesis.
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000601:surgery; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000145:classification* / Q000401:mortality; D006801:Humans; D008297:Male; D008404:Massachusetts; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000601:surgery; D013923:Thromboembolism / Q000209:etiology / Q000401:mortality / Q000601:surgery