Phosphoenolpyruvate carboxykinase is a nuclear enzyme in rats and chickens.
The presence of phosphoenolpyruvate carboxykinase (PEPCK) in the nuclei of chicken liver cells was confirmed using two experimental designs. PEPCK was found to be enriched in the nuclear fraction of rat liver, a species whose hepatic PEPCK is reported to be predominantly cytosolic. We suggest that PEPCK plays a role in nuclear synthesis of N-acetyl-neuraminic acid.
D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology*; D002645:Chickens; D004247:DNA / Q000378:metabolism; D005260:Female; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D004247:DNA; D005969:Glutamate Dehydrogenase; D010729:Phosphoenolpyruvate Carboxykinase (GTP)