title: Hypersensitivity reactions to Althesin infusion: measurement of complement involvement.
abstract: Two cases of hypersensitivity reactions in the course of slow infusion of Althesin are reported. Serial examination of their complement system showed a marked activation of the alternate pathway which returned almost to normal within 24 hours.
mesh_terms: D000293:Adolescent; D000328:Adult; D000530:Alfaxalone Alfadolone Mixture / Q000009:adverse effects*; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D003170:Complement Pathway, Alternative; D003165:Complement System Proteins / Q000032:analysis; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008297:Male; D013997:Time Factors
chemical_list: D000530:Alfaxalone Alfadolone Mixture; D003165:Complement System Proteins