title: [Experiences with intranasal and parenteral use of 1-desamino-8-D-arginine vasopressin (DDAVP). Use in the diagnosis of hypophyseal function].
abstract: While 1-desamino-8-D-arginine-vasopressin is not suitable for the functional diagnostics of the anterior pituitary gland, it has as in the therapy of the central diabetes insipidus a firm place also in its diagnostics. A hypothalamic neurohypophyseal system was demonstrated. Apart from a secure diagnostic evidence the test shows further advantages in comparison to the hitherto performed methods: an essentially smaller load for patient and personnel, a shorter duration and a simplified performance. First findings in patients with central diabetes insipidus, in a female patient with renal diabetes insipidus and patient without disturbance of the water balance are discussed. A control of our findings in other institutions is desirable.
mesh_terms: D000281:Administration, Intranasal; D001127:Arginine Vasopressin; D003894:Deamino Arginine Vasopressin; D003919:Diabetes Insipidus / Q000175:diagnosis*; D006801:Humans; D007275:Injections, Intravenous; D007671:Kidney Concentrating Ability / Q000187:drug effects; D010901:Pituitary Function Tests / Q000379:methods*; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D001127:Arginine Vasopressin; D003894:Deamino Arginine Vasopressin
vernacular_title: Erfahrungen bei der intranasalen und parenteralen Anwendung von 1-Desamino-8-D-Arginin-Vasopressin (DDAVP). Anwendung in der Hypophysenfuktionsdiagnostik.