title: [Statistical observation of the effect of maternal heart disease on pregnancy and fetus].
abstract: Fifty-four pregnancies with maternal heart disease, managed at the Tohoku University Hospital during the years 1976 to 1981, were reviewed and statistically analyzed for the effects of the disease. Twenty-six (48.1%) were complicated by rheumatic valvular disease, 26(48.1%) by congenital disease, and the remaining 2(3.7%) were miscellaneous. Forty-four cases who delivered after 24 weeks gestation were divided into two groups in terms of the occurrence of maternal decompensation during pregnancy. In the group of pregnancies with decompensation, when compared with the group without decompensation, the age of mothers was higher (p less than 0.02), length of gestation was shorter (p less than 0.005) and birth weight was smaller (p less than 0.01). On the other hand there were no significant differences between the group without decompensation and the control group. Analysis of covariance among the three groups, in which birth weight was assumed to be a function of the number of gestational weeks, suggested the shortening of gestation was relatively important in the occurrence of low-birth-weight in the group with decompensation. Apgar scores at 1 and 5 minutes and the occurrence of fetal distress were not significantly different among the groups. The effects of maternal decompensation on fetal growth and length of gestation were discussed.
mesh_terms: D000328:Adult; D000367:Age Factors; D001034:Apgar Score; D005260:Female; D005316:Fetal Distress / Q000453:epidemiology*; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000453:epidemiology; D006349:Heart Valve Diseases / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology*; D012214:Rheumatic Heart Disease / Q000453:epidemiology