title: Effect of niacin supplementation on milk production and ketosis of dairy cattle.
abstract: In two experiments with Holstein cows effects of dietary supplementation of niacin to periparturient cattle on subsequent milk production and ketosis were examined. In Experiment 1, 20 cows were assigned to two groups. The treatment group received niacin at 6 g per head per day for 2 wk prepartum and 12 g per head per day for 4 wk postpartum. The control group received no niacin. In Experiment 2, 40 cows were assigned to four groups of 10 cows. One group served as the control and the other three received 3, 6, or 12 g niacin per head per day for 10 wk postpartum. In both experiments niacin-supplemented groups produced slightly more milk than controls. There were no consistent changes of milk composition with treatment. Glucose concentration in blood serum was higher for cows receiving niacin. Concentrations of beta-hydroxybutyrate and nonesterified fatty acids in blood and plasma were generally lower for niacin-supplemented groups. Niacin supplementation had no effect on feed intake or body weight changes. In Experiment 1 there was a significant reduction of niacin concentration in red blood cells of postpartum cows not receiving supplemental niacin. Insulin concentration in blood serum in Experiment 2 was unaffected by niacin supplementation.
mesh_terms: D020155:3-Hydroxybutyric Acid; D000138:Acidosis / Q000662:veterinary*; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002417:Cattle / Q000378:metabolism*; D002418:Cattle Diseases / Q000517:prevention & control*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005527:Food, Fortified; D006885:Hydroxybutyrates / Q000097:blood; D007662:Ketosis / Q000517:prevention & control / Q000662:veterinary*; D007774:Lactation; D008892:Milk / Q000378:metabolism*; D009525:Niacin / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy; D011644:Puerperal Disorders / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D006885:Hydroxybutyrates; D009525:Niacin; D020155:3-Hydroxybutyric Acid