The effect of sleep deprivation on sleep in rats with suprachiasmatic lesions.
The effect of 24-h sleep deprivation on sleep was investigated in rats whose circadian rest-activity rhythms were extensively disrupted by bilateral lesions of the suprachiasmatic nuclei (SCN). Sleep deprivation caused an increase in total sleep, REM sleep and the slow wave sleep fraction of non-REM sleep. It is concluded that the homeostatic component of sleep regulation is morphologically and functionally distinct from the circadian component.
D000818:Animals; D001931:Brain Mapping; D002940:Circadian Rhythm; D008297:Male; D009043:Motor Activity / Q000502:physiology; D009334:Neck Muscles / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012890:Sleep / Q000502:physiology; D012892:Sleep Deprivation / Q000502:physiology*; D013493:Suprachiasmatic Nucleus / Q000502:physiology*