Allergies and agricultural exposure as risk factors for multiple myeloma.
In a case-control study of 84 multiple myeloma patients and 168 age- and sex-matched controls with tumours at other sites, reported prior allergies were associated with an elevated risk of myeloma (RR = 3.1, P less than 0.001). In addition, more myeloma patients than controls reported prior myxoedema (RR = 5.0, P = 0.04). History of agricultural work was associated with an elevated risk of myeloma (RR = 2.2, P = 0.01), although no detailed information was available on the type of farming in which the subjects were engaged. More detailed studies are required to confirm and further delineate these findings.
D000328:Adult; D000368:Aged; D000382:Agricultural Workers' Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000209:etiology*; D009230:Myxedema / Q000150:complications; D009369:Neoplasms / Q000209:etiology; D009784:Occupational Diseases / Q000209:etiology; D012306:Risk; D012959:Socioeconomic Factors