[Clinical significance of the blood level of alpha-cholesterol in diabetes mellitus].
The total and alpha-cholesterol content, as well as the triglyceride concentration were determined in 184 patients, suffering from diabetes mellitus of the I and II types, with or without ischemic heart disease (IHD) and in 96 persons with the disordered glucose tolerance test. It was stated that the alpha-cholesterol level in diabetics with the II type of the disease is lower than that in the controls and patients with the I type of diabetes mellitus. In males and females with the II type of diabetes mellitus the alpha-cholesterol level is lower than that of the controls. In males with the I type of the disease its concentration is higher and in females is the same as in the controls. In the presence of IHD the alpha-cholesterol level is lower comparatively to that of the controls (males and females) with diabetes mellitus of the II type and in females with the I type. In males with the II diabetes type and IHD the alpha-cholesterol level is lower than that of the males with the I type and IHD. In females there are no significant differences. The difference in the alpha-cholesterol content, depending on the patient's sex, is seen only in persons with diabetes mellitus of the II type, aged 45 to 65 years, and in patients with the I type, aged 30 to 45 years. Sex differences in the triglyceride content of patients with diabetes mellitus of thek I and II types mere not observed, their level being higher than that of the controls.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000097:blood / Q000150:complications; D048909:Diabetes Complications; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D006888:Hydroxycholesterols / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D006888:Hydroxycholesterols; D014280:Triglycerides; C011724:cholest-5-en-3 beta,7 alpha-diol; D002784:Cholesterol
Klinicheskoe znachenia soderzhaniia v krovi al'fa-kholesterina u bol'nykh sakharynm diabetom.