title: Dolichyl phosphate supplementation increases N-linked protein glycosylation in rat parotid acinar cells without increasing glycoprotein secretion.
abstract: N-linked protein glycosylation was increased three- to five-fold, in dispersed rat parotid acinar cells in vitro, by supplementation with exogenous dolichylphosphate. Despite this increase, glycoprotein secretion from both control and dolichylphosphate-supplemented cells was comparable.
mesh_terms: D000818:Animals; D004288:Dolichol Phosphates / Q000494:pharmacology*; D006023:Glycoproteins / Q000096:biosynthesis* / Q000378:metabolism; D007700:Kinetics; D007930:Leucine / Q000378:metabolism; D008297:Male; D008358:Mannose / Q000378:metabolism*; D010306:Parotid Gland / Q000166:cytology / Q000378:metabolism*; D011106:Polyisoprenyl Phosphates / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004288:Dolichol Phosphates; D006023:Glycoproteins; D011106:Polyisoprenyl Phosphates; C028306:dolichol monophosphate; D007930:Leucine; D008358:Mannose