Differences in toxicity and antigenicity between mistletoe lectin I and viscotoxin A 3.
In contrast to mistletoe lectin I (ML I), viscotoxin A 3 does not inhibit protein synthesis in cell-free systems. From the immunological studies it is concluded that ML I and viscotoxin do not share identical structural domains.
D000818:Animals; D000941:Antigens; D002474:Cell-Free System; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D006461:Hemolysis / Q000187:drug effects; D066298:In Vitro Techniques; D014784:Mistletoe; D028321:Plant Preparations; D010940:Plant Proteins; D010946:Plants, Medicinal; D014176:Protein Biosynthesis / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D054790:Ribosome Inactivating Proteins, Type 2; D014118:Toxins, Biological / Q000276:immunology / Q000633:toxicity*
D000941:Antigens; D028321:Plant Preparations; D010940:Plant Proteins; D054790:Ribosome Inactivating Proteins, Type 2; D014118:Toxins, Biological; C488862:mistletoe lectin I; C009674:ribosome inactivating protein, Viscum; C488038:viscotoxin