Effect of leucogenenol, a thymothyroid hormone, on the enzymes and several other constituents of the serum.
It has been found that rats treated with the thymothyroid hormone, leucogenenol, have significantly elevated levels of alkaline phosphatase and lactate dehydrogenase in their serum 8 hrs. later. These levels remain elevated for 24 hrs. and 12 hrs., respectively. The concentrations of creatine phosphokinase and aspartate aminotransferase as well as total protein, albumin, calcium, inorganic phosphorus, glucose, urea nitrogen, uric acid and creatinine in the serum are not affected by treatment with leucogenenol. These results are in agreement with the previously reported findings that treatment with leucogenenol increases the rate of development of blood cells of the bone marrow, increases the rate of recovery from immunosuppression and enhances the immune response.
D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007932:Leucogenenol / Q000494:pharmacology*; D007962:Leukocytes / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013141:Spiro Compounds / Q000494:pharmacology*
D013141:Spiro Compounds; D007932:Leucogenenol; D007770:L-Lactate Dehydrogenase; D000469:Alkaline Phosphatase