Thermal injury in an adrenalectomized patient.
The occurrence of thermal injury in an adrenalectomized patient on long-term steroid replacement therapy illustrated the role of adrenal hormones in the systemic responses to thermal injury. This unusual patient demonstrated an inadequate response to fluid resuscitation and excessive third-space fluid losses, defective thermogenesis, profound nutritional abnormalities, impaired wound healing, and compromised immunologic function. Nutritional support required correction of calorie-nitrogen proportions from 180:1 to 90:1, following which the patient was in positive nitrogen balance.
D000311:Adrenal Glands / Q000502:physiology* / Q000601:surgery; D000328:Adult; D002056:Burns / Q000503:physiopathology* / Q000628:therapy; D003480:Cushing Syndrome / Q000150:complications / Q000276:immunology / Q000503:physiopathology; D005440:Fluid Therapy; D006801:Humans; D008297:Male