[Effect of ronidazole on the growth of weaned piglets and the levels of urea nitrogen in plasma and blood glucose].
Four experiments were carried out on 412 piglets, reared in different environmental conditions in the period from 4 to 12 weeks of life. Ronidazole appeared to be the most valuable feed supplement among those studied: OTC, virginiamycin, LBC, SRE and bycitracin. In comparison with OTC it significantly improved weight increment of piglets from 8.1% to 15.4%, as well as utilization of feed from 4.0% to 9.1% with a significant decrease of morbidity and falls. The effect of the action of ronidazole was marked the strongest in young piglets directly after weaning, in less developed ones and those kept in unfavourable environmental conditions. Ronidazole did not cause changes in glucose concentration in blood, but in decreased the level of urea nitrogen in plasma. Mean concentration of urea nitrogen in piglets receiving ronidazole ranged from 16.9 to 17.6 mg/100 cm3, while in the control with OTC it ranged from 17.8 to 18.9 mg/100 cm3. A lower urea concentration in piglets in the group with ronidazole may indicate that, in comparison with OTC, it inhibited to a larger extent bacterial degradation of amino-acids and ureolysis of urea in tissues and alimentary canal content of piglets.
D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D005527:Food, Fortified; D009593:Nitroimidazoles / Q000494:pharmacology*; D012385:Ronidazole / Q000494:pharmacology*; D013552:Swine / Q000254:growth & development*; D014886:Weaning
D001786:Blood Glucose; D009593:Nitroimidazoles; D012385:Ronidazole
Wpływ ronidazolu na wzrost odsadzonych prosiat oraz poziom N-mocznikowego osocza i glukozy we krwi.