title: Post-mortem glycosylated hemoglobin (HbA1c): evidence for a history of diabetes mellitus.
abstract: Glycosylated hemoglobin (HbA1c) levels on blood obtained from 28 cadavers were compared with that of healthy volunteers and patients with diabetes mellitus. Levels of HbA1c did not correlate with post-mortem intervals of four to 36 hours, suggesting that HbA1c is stable under these conditions. All deceased with a history of diabetes mellitus, five cases, had an elevated post-mortem blood HbA1c. Twenty-three deceased had a negative history for diabetes mellitus and seven of this group had an elevated HbA1c. These seven cases had diagnosis of malignancies and a history of prolonged exposure to steroids in excess compared to the remaining 16 cases.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy; D011180:Postmortem Changes
chemical_list: D000305:Adrenal Cortex Hormones; D006442:Glycated Hemoglobin