The determination of cocaine and its major metabolite, benzoylecgonine, in postmortem fluids and tissues by computerized gas chromatography/mass spectrometry.
An analytical procedure for the simultaneous determination of both cocaine and benzoylecgonine in postmortem fluid and tissue samples has been developed by using computerized gas chromatography/mass spectrometry and gas chromatography using a nitrogen/phosphorus (N/P) detector. Both methods are accurate and sensitive and allow the determination of tissue concentrations of cocaine and benzoylecgonine as low as 0.015 microgram/mL.
D001344:Autopsy; D003042:Cocaine / Q000031:analogs & derivatives* / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans
C005618:benzoylecgonine; D003042:Cocaine