[Proliferative activity and the rate of differentiation of rat bone marrow cells in normal conditions and in early periods of acute radiation sickness].
The autoradiographic method was used to study proliferative activity of cells of a myeloid and erythroid compartments of the bone marrow of intact and irradiated (a single exposure of 10 Gy) rats. The proliferative activity and differentiation rate of cells decreased at early times after irradiation. It was shown that giant neutrophils had heavy tracer nuclei, were formed from myeloblasts, being at the most active phase of the S stage at the time of irradiation, and had a very low differentiation rate.
D000208:Acute Disease; D000818:Animals; D001345:Autoradiography; D002454:Cell Differentiation / Q000528:radiation effects; D002455:Cell Division / Q000528:radiation effects; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D051381:Rats
Proliferativnaia aktivnost' i skorost' differentsirovki kletok kostnogo mozga krys v norme i v rannie sroki ostroĭ luchevoĭ bolezni.