Long-acting contraceptive agents: norethisterone esters of polyunsaturated acids.
Some new derivatives of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) are described in which the 17 beta-hydroxyl group of the steroid is esterified with polyunsaturated aliphatic acids. The potential of these compounds as long-acting contraceptive agents has been evaluated.
D000143:Acids; D003692:Delayed-Action Preparations; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009640:Norethindrone / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013053:Spectrophotometry; D013329:Structure-Activity Relationship
D000143:Acids; D003692:Delayed-Action Preparations; D007202:Indicators and Reagents; D009640:Norethindrone