[Radio-protective effect of sulfur-containing methylfuran derivatives and the role of thiols in its realization].
In experiments on mice it was demonstrated that S-containing methylfuran derivatives were highly radioprotective (50-70% survival of exposed animals). The preparations under study did not influence the redox potential in tissues and did not change the content of nonprotein SH-groups in the radiosensitive organs.
D000818:Animals; D005663:Furans / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D051379:Mice; D010084:Oxidation-Reduction; D011833:Radiation Injuries, Experimental / Q000378:metabolism / Q000517:prevention & control*; D011837:Radiation-Protective Agents; D013154:Spleen / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000378:metabolism / Q000494:pharmacology*
D005663:Furans; D011837:Radiation-Protective Agents; D013438:Sulfhydryl Compounds; C029060:2-methylfuran
Radiozashchitnyĭ éffekt serosoderzhashchikh proizvodnykh metilfurana i rol' tiolov v ego realizatsii.