title: Locomotor activity, auditory startle and shock thresholds in spontaneously hypertensive rats.
abstract: A group of SHRs and a group of WKY normotensive controls were compared sequentially on open-field behavior, Y-maze activity, responsiveness and habituation of the auditory startle response, and shock thresholds. In the open field and Y maze the SHRs were more active than the WKYs, but the locomotor activity of the SHRs decreased more within sessions. However, the SHRs could be described as showing more, less or the same between-session habituation depending upon the apparatus and the portion of the session analyzed. The SHRs were less responsive than controls on the auditory startle response measure, and they did not differ from controls on startle-response habituation. The SHRs were less responsive than controls at low shock levels but more responsive at high shock levels. The relationship between SHRs and WKYs on the responsiveness dimension depended upon the modality and intensity of the stimulus, the response characteristics of the test situation, and the time sample of behavior taken.
mesh_terms: D000818:Animals; D001794:Blood Pressure; D004597:Electroshock; D005106:Exploratory Behavior / Q000502:physiology; D006185:Habituation, Psychophysiologic; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D010146:Pain / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D013216:Reflex, Startle / Q000502:physiology*; D012684:Sensory Thresholds