title: Digestion of maltitol in man, rat, and rabbit.
abstract: Maltitol is found to be enzymatically hydrolyzed by the small intestinal mucosa of man, rat, and rabbit and metabolized by everted sacs of rabbit intestine at a moderate rate. On in vivo perfusion of maltitol (15.3 mumol/min) through the small intestine, 19% of the sugar alcohol is digested by gnotobiotic rats. 120 min after stomach intubation of gnotobiotic rats, only 31% of the ingested maltitol is found in the ileum. A daily application of 35 g maltitol to 4 human beings does not influence the parameters of well-being, compatibility and fecal state. It is concluded that maltitol will be digested and utilized by man, rat, and rabbit.
mesh_terms: D000328:Adult; D000818:Animals; D004063:Digestion; D005243:Feces / Q000032:analysis; D005260:Female; D005856:Germ-Free Life; D006801:Humans; D006868:Hydrolysis; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism*; D007421:Intestine, Small / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008320:Maltose / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D013402:Sugar Alcohols / Q000032:analysis / Q000378:metabolism*; D013549:Sweetening Agents / Q000378:metabolism*
chemical_list: D013402:Sugar Alcohols; D013549:Sweetening Agents; D008320:Maltose; C010745:maltitol