Sex-associated relationships between cell counts and lymphoproliferative responses in healthy young adults.
Correlation analyzes of lymphoproliferative responses, total T (E-rosettes) cell levels and autologous rosette-forming cell (A-RFC) levels of healthy human volunteers revealed previously unsuspected sex-associated differences. A negative association existed between response to Con A and E-rosette levels in men, and between PHA lymphoproliferation and E-rosette counts in women, whereas mitogen-induced responses and A-FRC levels varied independently in either sex. Total T cell and A-RFC counts correlated only in man.
D000328:Adult; D002455:Cell Division; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D010835:Phytohemagglutinins / Q000494:pharmacology; D012397:Rosette Formation; D012737:Sex Factors
D010835:Phytohemagglutinins; D003208:Concanavalin A