title: Central nervous system reactions during heliox and trimix dives to 51 ATA, DEEP EX 81.
abstract: Two groups of divers were compressed to 500 msw with heliox (n = 3) and trimix (n = 3). They were followed with repeated neuropsychological and neurological tests during compression, at stable intermediate depths, and at 500 msw. For the heliox group there was a marked increase in tremor and EEG slow waves and reduction in handgrip strength. For the trimix group the tremor increase did not occur, but the EEG changes were the same as in the heliox group. On motor tests only the trimix group showed impaired finger dexterity and manual dexterity. The same occurred for fine visuomotor coordination, but both groups had increased intentional tremor. On cognitive tests the same difference occurred. The trimix group was markedly impaired in reasoning and long-term memory, while only a mild impairment was found in the heliox group. Dizziness and other symptoms of high pressure nervous syndrome (HPNS) occurred in both groups.
  
  
  CONCLUSIONS
  There were marked HPNS effects during compression for both groups. Only tremor was inhibited by the nitrogen. In addition, the trimix group was impaired because of nitrogen narcosis. These data indicated that 10% nitrogen did not inhibit HPNS effects during compression to 500 msw, but the considerable differences between subjects shows that susceptibility to compression must be an important area for future research.
mesh_terms: D000328:Adult; D001273:Atmosphere Exposure Chambers; D002490:Central Nervous System / Q000502:physiology*; D003071:Cognition / Q000502:physiology; D004242:Diving; D004569:Electroencephalography; D006371:Helium; D006801:Humans; D007222:Inert Gas Narcosis / Q000503:physiopathology; D008297:Male; D009048:Motor Skills / Q000502:physiology; D009584:Nitrogen; D010100:Oxygen; D011597:Psychomotor Performance / Q000502:physiology; D014202:Tremor / Q000209:etiology
chemical_list: D006371:Helium; D009584:Nitrogen; D010100:Oxygen