title: X-ray microanalysis of hepatocytes in thyroidectomized rats.
abstract: Thyroid hormones are assumed to be a factor which influences elemental distribution in animal tissues, including liver, by their action on the passive Na-K permeability of cell membrane (Folke and Sestoft, 1977) and/or by stimulation of the Na-K pump (Ismail-Beigi and Edelman, 1970), as well as by the enhancement of tubular reabsorption of Na and Cl in kidneys (Discala and Kinney, 1971). We have shown previously that thyroxine administration does not significantly change intracellular ion concentrations in rat hepatocytes (Smith et al., 1983). In the present study we have used X-ray microanalysis to examine the effect of thyroidectomy on the elemental content of rat hepatocytes.
mesh_terms: D000818:Animals; D004573:Electrolytes / Q000032:analysis*; D004577:Electron Probe Microanalysis; D008099:Liver / Q000032:analysis* / Q000166:cytology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013965:Thyroidectomy
chemical_list: D004573:Electrolytes