Iohexol compared with metrizoate in urography.
Urography was performed in 20 patients using the new non-ionic contrast medium iohexol (Omnipaque) and in 22 patients using the conventional ionic medium metrizoate (Isopaque) in a randomized, double blind comparison. Iohexol caused significantly less subjective reactions and less tachycardia than metrizoate. No significant difference between the contrast media was observed regarding the influence on blood pressure, hematologic parameters, or clinical chemical parameters in blood and urine. Urographic films of similar and high quality were obtained with both contrast media.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003287:Contrast Media / Q000009:adverse effects; D004361:Drug Tolerance; D005260:Female; D006339:Heart Rate; D006801:Humans; D007463:Iodobenzoates / Q000009:adverse effects; D007472:Iohexol; D008297:Male; D008794:Metrizoic Acid / Q000009:adverse effects; D008875:Middle Aged; D011674:Pulse; D011856:Radiographic Image Enhancement; D014283:Triiodobenzoic Acids / Q000009:adverse effects; D014567:Urography
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008794:Metrizoic Acid