Human polymorphonuclear neutrophil functions are unaffected by human interferon-alpha 2.
Leukocyte-derived interferons have been reported to enhance the functions of polymorphonuclear neutrophils. This study reveals no effect of the highly purified recombinant DNA-produced human interferon-alpha 2 on the oxidative, chemotactic, adherent, phagocytic, and bactericidal activities of human polymorphonuclear neutrophils in vitro.
D004274:DNA, Recombinant; D006801:Humans; D007370:Interferon Type I / Q000302:isolation & purification / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology
D004274:DNA, Recombinant; D007370:Interferon Type I