Long term effects of neonatal hypothyroidism on pituitary estradiol binding sites in the female rat.
Two months after recovery from a perinatal hypothyroidism (PTU), the total amount of pituitary estradiol binding sites (EBS) was still dramatically reduced, but the actual concentration of EBS had returned to control levels.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D005260:Female; D007037:Hypothyroidism / Q000139:chemically induced / Q000378:metabolism*; D010902:Pituitary Gland / Q000378:metabolism*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011441:Propylthiouracil; D051381:Rats; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000378:metabolism*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011441:Propylthiouracil