title: [Clinico-epizootiological and pathomorphological studies of "marble spleen" disease in pheasants].
abstract: Described are the clinical and epizootiological aspects and the morphological lesions in pheasants affected with the marble spleen disease at its first outbreaks. The disease was found to run a peracute course with a 100 per cent lethal effect. Mortality rate reached 5.6 per cent, the male birds being affected much more rarely than the female ones -- up to 1.8 per cent. The spleen is invariably enlarged two to four times, with marble appearance due to the numerous gray-whitish nodules. Histologically, there were necroses with the abundant deposition of achromatic amyloid. The reticular cells presented large numbers of intranuclear inclusion bodies, mainly of two types -- large eosinophilic ones, filling the whole nucleus, and smaller ones of basophilic reaction, surrounded by a pale halo and located in the center of the nucleus. In the lungs there were strongly manifested oedema and hyperemia, and more rarely -- necrotic foci with the deposition of amyloid. The liver and kidneys presented degenerative lesions of a varying intensity, and there were also intranuclear bodies in the reticulo-endothelial cells. Amyloid was also found in the glomerules.
mesh_terms: D000682:Amyloid / Q000378:metabolism; D000818:Animals; D002031:Bulgaria; D006651:Histocytochemistry; D009336:Necrosis; D011200:Poultry; D011201:Poultry Diseases / Q000453:epidemiology* / Q000378:metabolism / Q000473:pathology; D013154:Spleen / Q000378:metabolism / Q000473:pathology; D013158:Splenic Diseases / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*
chemical_list: D000682:Amyloid
vernacular_title: Kliniko-epizootologichni i patomorfologichni prouchvaniia na zaboliavaneto "mramoren dalak" po fazanite.