Effect of etretinate on chemotaxis of neutrophils from patients with pustular and vulgar psoriasis.
The chemotactic activities of neutrophil granulocytes of patients with pustular and vulgar psoriasis were evaluated before and after treatment with etretinate. Control values before treatment were significantly different from those of vulgar psoriasis group but not from the pustular psoriasis group. The difference between the 2 groups with psoriasis was significant. Etretinate causes a significant reduction in neutrophil chemotaxis in pustular psoriasis patients and a less pronounced reduction in those with vulgar psoriasis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D005050:Etretinate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D011565:Psoriasis / Q000276:immunology*; D013492:Suppuration
D005050:Etretinate