title: Spectrophotometric investigation of pulsatile blood flow for transcutaneous reflectance oximetry.
abstract: A new method to estimate arterial oxygen saturation is suggested based on the presence of the plethysmographic pulse. A prototype skin reflectance oximeter system utilizing a miniature solid state optical transducer has been constructed. Preliminary data collected from a group of volunteers indicated good quantitative correlation between skin reflectance and arterial oxygen saturation as determined by an earlobe oximeter. We are now investigating the dependency of the measurements on various physiological conditions and skin characteristics in order to determine appropriate calibration procedures. This study has demonstrated for the first time that arterial hemoglobin oxygen saturation can be measured quantitatively using transcutaneous reflectance techniques. However, more extensive work is needed to further develop this technique into a viable clinical tool.
mesh_terms: D006801:Humans; D008027:Light; D010092:Oximetry / Q000379:methods*; D010108:Oxyhemoglobins / Q000032:analysis*; D010991:Plethysmography / Q000379:methods; D012542:Scattering, Radiation
chemical_list: D010108:Oxyhemoglobins