Membranous lipodystrophy (lipomembranous polycystic osteodysplasia). Two case reports.
Membranous lipodystrophy, a hereditary disease, is characterized by symmetric multiple cystic bone lesions and progressive neuropsychiatric symptoms. In two patients, a 22-year-old woman and a 30-year-old man, as in others reported in the literature, neither the etiology nor the pathogenesis was apparent. Histologically, the lesions consisted of convoluted membranes interlaced with lipoid structures.
D000328:Adult; D001845:Bone Cysts / Q000235:genetics* / Q000473:pathology; D002462:Cell Membrane / Q000473:pathology; D005260:Female; D006801:Humans; D008060:Lipodystrophy / Q000235:genetics* / Q000473:pathology; D008297:Male; D013577:Syndrome