Effect of sleep deprivation as a predictor of treatment response to antidepressant medication.
Sixty depressed patients were treated first with sleep deprivation (SD) and afterwards with clomipramine or maprotiline. A statistically significant correlation was found between the positive effect of SD and response to clomipramine and the negative effect of SD and response to maprotiline.
D000328:Adult; D000368:Aged; D000873:Anthracenes / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008376:Maprotiline / Q000627:therapeutic use*; D008875:Middle Aged; D012892:Sleep Deprivation
D000873:Anthracenes; D008376:Maprotiline; D002997:Clomipramine