title: Native American medicinal plants. Anemonin from the horse stimulant Clematis hirsutissima.
abstract: Anemonin, the dilactone of cyclobutane-1,2-diol-1,2-diacrylic acid derived from the cyclodimerization of protoanemonin, a known blistering agent, was isolated from Clematis hirsutissima, a plant used by the Nez Perce and Teton Sioux nations as a horse stimulant.
mesh_terms: D000818:Animals; D005663:Furans; D006736:Horses / Q000502:physiology; D010946:Plants, Medicinal / Q000032:analysis*; D013729:Terpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014481:United States
chemical_list: D005663:Furans; D013729:Terpenes; C028304:anemonin