Effect of repeated treatments with sympathomimetic drugs on planarian glucose metabolism.
In response to sympathomimetic drugs (epinephrine, dopamine, isoproterenol, ephedrine), glucose utilization was enhanced in planarians. Upon repeated treatment with test substances one week after the first exposure the rate of glucose utilization differed from that observed at the first exposure. Under such conditions the responses appeared to vary depending on which of the drugs was used at the first exposure. After the elapse of two additional weeks the phenomenon (memory) was not further increased but the responses still differed from those recorded at the first exposure or two weeks after a single exposure.
D000818:Animals; D005947:Glucose / Q000378:metabolism*; D010932:Planarians / Q000187:drug effects / Q000378:metabolism*; D013566:Sympathomimetics / Q000494:pharmacology*; D014419:Turbellaria / Q000378:metabolism*
D013566:Sympathomimetics; D005947:Glucose