title: [Iris angiography and endothelium microscopy in dysgenesis mesodermalis iridis et corneae].
abstract: Three patients with endothelialization of the anterior chamber - 2 with Chandler's syndrome and 1 with Cogan-Reese syndrome - were followed up by means of iris angiography and specular microscopy over a period of several years. The endothelial angiographic changes occurred simultaneously in all cases; the more pronounced the endothelial changes, the more severe the iris changes. Since iris stroma and corneal endothelium develop from a common mesenchymal origin, and the extent of the changes they undergo is similar in the course of the diseases in question, a close relationship between Rieger's mesodermal dysgenesis, Chandler's syndrome and Cogan-Reese syndrome is postulated.
mesh_terms: D000328:Adult; D000867:Anterior Chamber; D003315:Cornea / Q000002:abnormalities* / Q000098:blood supply; D004727:Endothelium / Q000098:blood supply; D005451:Fluorescein Angiography; D006801:Humans; D007498:Iris / Q000002:abnormalities* / Q000098:blood supply; D008648:Mesoderm; D008853:Microscopy; D008875:Middle Aged; D011680:Pupil; D013577:Syndrome
vernacular_title: Irisangiographie und Endothelmikroskopie bei Dysgenesis mesodermalis iridis et corneae.