Interpretation of the effects of propranolol on coronary reactive hyperaemia.
The effect of propranolol on the hyperaemic response after transient coronary arterial occlusion has been evaluated. The excess volume of blood delivered to the myocardium after an occlusion is diminished after propranolol in proportion to the reduced coronary blood flow. From the findings it is not necessary to postulate a change in the intrinsic mechanisms of reactive hyperaemia after propranolol has been given.
D000818:Animals; D001810:Blood Volume / Q000187:drug effects; D003326:Coronary Circulation / Q000187:drug effects*; D004285:Dogs; D006940:Hyperemia / Q000188:drug therapy*; D011433:Propranolol / Q000627:therapeutic use*
D011433:Propranolol