Influence of the hormonal balance of late pregnancy on the active uptake of 5-hydroxytryptamine by human blood platelets.
The active uptake of 5-hydroxytryptamine (5-HT) was studied in vitro in the blood platelets of twelve pregnant women during their final two months of pregnancy. The control group consisted of twelve women who were, on average, four days post partum. No significant difference in the uptake of 5-HT by blood platelets was found between these groups. Thus, the rapid fall in blood estrogen and progesterone concentrations after parturition did not seem to influence the uptake of 5-HT in human blood platelets.
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D004967:Estrogens / Q000097:blood; D005260:Female; D006801:Humans; D049590:Postpartum Period; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D012701:Serotonin / Q000097:blood*
D004967:Estrogens; D012701:Serotonin; D011374:Progesterone