An aetiological evaluation of increased occurrence of congenital limb reduction abnormalities in Hungary, 1975-1978.
In Hungary a significant increase occurred in the birth prevalence of congenital limb reduction abnormalities from 1975 to 1978 after the introduction of a new population policy in 1974. A case-control study showed a slight increased use of drugs for ovulation induction, oral contraceptives prior to conception and more frequent extramarital births as well as unwanted pregnancies.
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology; D003276:Contraceptives, Oral / Q000009:adverse effects; D003625:Data Collection; D004967:Estrogens / Q000009:adverse effects; D005260:Female; D006801:Humans; D006814:Hungary; D017880:Limb Deformities, Congenital; D008572:Menarche; D008599:Menstruation Disturbances / Q000150:complications; D010062:Ovulation Induction; D011247:Pregnancy; D011275:Pregnancy, Unwanted
D003276:Contraceptives, Oral; D004967:Estrogens