An autopsied case of a two-month-old infant with granulomatous pancarditis having severe vasculitis and valvulitis.
A 2-month-old female infant with pancarditis was reported. The patient died after a 26-day clinical course. The autopsy showed pancarditis, including inflammation in all 4 valves and chordae, fibrinoid vasculitis, pharyngolaryngitis and atrophy of the lymph nodes. Microscopic examination revealed proliferative inflammation in the endocardium, valve, myocardium, epicardium and coronary vessels. The histological findings suggested the etiology to be a rheumatic-type reaction at an extremely young age.
D001167:Arteritis / Q000150:complications* / Q000473:pathology; D003327:Coronary Disease / Q000150:complications* / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000473:pathology*; D006349:Heart Valve Diseases / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D009205:Myocarditis / Q000150:complications / Q000473:pathology*; D009206:Myocardium / Q000473:pathology