Effect of intravenous 3-hydroxybutyrate on postoperative nitrogen balance.
Thirty-two patients routinely admitted for cholecystectomy were allocated randomly to receive a post-operative fluid regimen containing either 18 g/d of sodium DL-3-hydroxybutyrate, or isoenergetic glucose, each for 3 d. The difference in the post-operative mean daily urinary nitrogen excretion between the control (median 8.3 g/d) and the 3-OH-butyrate groups (median 8.3 g/d) was not statistically significant, nor was there any difference when allowances were made for patient's surface area or for changes in blood urea during the course of the study.
D000328:Adult; D002763:Cholecystectomy; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D006885:Hydroxybutyrates / Q000008:administration & dosage*; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism* / Q000652:urine; D011184:Postoperative Period; D013514:Surgical Procedures, Operative
D006885:Hydroxybutyrates; D005947:Glucose; D009584:Nitrogen