title: Chronic exposure of the eggs and adults of Biomphalaria glabrata (Say) to the molluscicide, nicotinanilide.
abstract: Some effects of chronic, low-dosage treatment of Biomphalaria glabrata eggs and adults with nicotinanilide, are reported. The susceptibility of eggs decreased with age. The development and hatching of 0-1 day old eggs could be prevented by continuous exposure to 0.0005-0.001 mg/l-1 whereas prehatch stages had a susceptibility similar to that of adult snails (0.1-0.2 mg/l-1). The possible use of slow-release formulations of nicotinanilide in the control of field populations of snails and schistosomiasis transmission is discussed.
mesh_terms: D000375:Aging; D000818:Animals; D001700:Biomphalaria; D004199:Disease Vectors; D004353:Drug Evaluation, Preclinical; D005260:Female; D008975:Molluscacides / Q000008:administration & dosage / Q000494:pharmacology*; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000494:pharmacology*; D010063:Ovum / Q000187:drug effects* / Q000254:growth & development; D012552:Schistosomiasis / Q000517:prevention & control / Q000635:transmission; D013997:Time Factors
chemical_list: D008975:Molluscacides; D009539:Nicotinic Acids; C038997:nicotinanilide