Cytotoxicity of sodium monofluorophosphate.
Sodium monofluorophosphate (MFP) was cytotoxic to fluoride-sensitive cells in culture, but not to fluoride-resistant cells, indicating that the cytotoxicity of MFP is due to fluoride ions, a hydrolysis product of MFP.
D000818:Animals; D002470:Cell Survival / Q000187:drug effects*; D003470:Culture Media; D004351:Drug Resistance; D005347:Fibroblasts; D005459:Fluorides / Q000633:toxicity*; D051379:Mice; D010710:Phosphates / Q000633:toxicity*; D012969:Sodium Fluoride / Q000494:pharmacology; D013997:Time Factors
D003470:Culture Media; D010710:Phosphates; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides