Male to male transmission of the G syndrome.
A father and son with hypertelorism and hypospadias are reported. The father has further, relatively mild, signs of the G syndrome, but his son has severe manifestations, including stridor, feeding difficulties and cardiac anomalies. This supports autosomal dominant inheritance.
D000328:Adult; D002648:Child; D003394:Craniofacial Dysostosis / Q000235:genetics*; D005799:Genes, Dominant; D006801:Humans; D006972:Hypertelorism / Q000235:genetics*; D007021:Hypospadias / Q000235:genetics*; D008297:Male; D013577:Syndrome