Comparison of cytotoxicity and thin-layer chromatography methods for detection of mycotoxins.
Thirty-three standard mycotoxins were assayed by thin-layer chromatography and by cytotoxicity in HEp-2 and Chang cells. Various levels of detection were found. The cytotoxicity test was significantly more sensitive than thin-layer chromatography for the trichothecenes and should be useful for screening extracts from animal feedstuffs for the presence of unknown mycotoxins.
D001681:Biological Assay; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002855:Chromatography, Thin Layer; D009183:Mycotoxins / Q000032:analysis* / Q000633:toxicity
D009183:Mycotoxins