title: [Senile changes in the resorption and elimination processes and their importance in pharmacotherapy].
abstract: On the basis of experimental and theoretical examinations the senile changes in man's absorbent system and renal excretory function were analysed. It was found that intestinal absorption and summary elimination are delayed with advancing years. Practical consequences with regard to dosage and dosage intervals can be derived for geriatric pharmacotherapy. By the example of selected groups of drugs the necessity for revised dosage instructions and application intervals in old age is explained.
mesh_terms: D000368:Aged; D000375:Aging; D000900:Anti-Bacterial Agents / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004358:Drug Therapy; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D007668:Kidney / Q000502:physiology*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D004364:Pharmaceutical Preparations
vernacular_title: Alternsveränderungen der Resorptions- und Eliminationsprozesse und ihre Bedeutung für die Pharmakotherapie.