[Thioamide derivatives with gastro-protective activity].
A series of 3-aryl-prop-2-enthioamide derivatives has been synthesized. These compounds were evaluated for gastro-protective activity in the rat. It has been shown that the N,N-dimethylamino derivative was the most active compound in this series [Table I comp. (II)].
D000577:Amides / Q000138:chemical synthesis*; D000818:Animals; D005765:Gastrointestinal Agents / Q000138:chemical synthesis*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013854:Thioamides / Q000138:chemical synthesis* / Q000494:pharmacology
D000577:Amides; D005765:Gastrointestinal Agents; D013854:Thioamides
Derivati tioamidici ad attività gastroprotettiva.