title: Cranial chordomas in children and young adults.
abstract: A series of 12 surgically treated and pathologically proven cranial chordomas presenting in children and young adults is reviewed. These rare tumors occur in relation to the path of the primitive notochord; four were parasellar, six were mid-clival, and two were inferior clival in location. Pathological evaluation revealed five of the tumors to have a significant chondroid component. Follow-up studies ranging from 1 month to 21 years revealed that eight patients were alive, all of whom had received radiation therapy following surgery.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002817:Chordoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D012888:Skull Neoplasms / Q000473:pathology* / Q000601:surgery