title: Comparison of skeletal muscle motor unit discharge characteristics in young and aged humans.
abstract: The purpose of this study was to determine the discharge characteristics of motor unit action potentials. Three decades of aged subjects ranging from 60 to 90 yr of age were compared to a group of 20-35 yr olds. Motor unit behavior was described by the interspike interval (ISI) and expressed statistically as a mean, a floating standard deviation (FSD), and a floating serial correlation (FRHO). The 70- to 79-yr-old group tended to have a slow motor unit discharge rate, an increased variability of discharge (FSD) and a negative serial correlation coefficient (FRHO). All three factors describing motor unit discharge behavior possibly suggest substitution of larger motor units for small motor units normally active at low tensions for the 70-79 age group.
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D000375:Aging; D006801:Humans; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009132:Muscles / Q000502:physiology*