title: [Increased information value of the radiophosphorus diagnosis of pigmented skin neoplasms].
abstract: A complex of new methods are proposed. They make it possible to improve the precision and informative value of the results of 32P diagnosis of pigmental skin tumors. The following methods are used: 1) fractional administration of the indicator to increase the level of 32P accumulation in melanomas; it made it possible to improve the differential-diagnostic capacity of the radiophosphorus test; 2) beta-radiometry of pathological and control skin zones with and without fine tissue equivalent filters to "contrast" tumors and to determine the average depth of their invasion to unchanged tissues; the use of this method made it possible to lessen the number of false-negative diagnoses and to get additional clinicodiagnostic information that can be useful in the planning of surgical and radiation treatment; 3) radiometry of skin zones in the spectrometric regimen with three different levels of the integral discrimination of beta-radiation impulses to determine the thickness and lower line of the layer of the abnormal accumulation of the indicator in the pathological skin zone; the use of this method makes it possible to detect incrusted melanomas.
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008433:Mathematics; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000378:metabolism; D008722:Methods; D009361:Neoplasm Invasiveness; D010761:Phosphorus Radioisotopes / Q000008:administration & dosage / Q000378:metabolism; D011877:Radionuclide Imaging; D012867:Skin / Q000000981:diagnostic imaging / Q000378:metabolism; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D010761:Phosphorus Radioisotopes
vernacular_title: Povyshenie informativnosti radiofosfornoĭ diagnostiki pigmentnykh novoobrazovaniĭ kozhi.