title: Studies on fat digestion, absorption, and transport in the suckling rat. IV. In vivo rates of triacylglycerol secretion by intestine and liver.
abstract: The rate of triacylglycerol entry into plasma in 14- to 15-day-old suckling rats was measured using the Triton WR1339 method. When the pups were left with the mother and allowed to nurse continually, the rate was 31.8 +/- 2.3 mumol/hr per rat. If the pups were removed from the mother with full stomachs and kept in a warm box at 30-32 degrees C, the rate was 12.5 +/- 1.5 mumol/hr per rat. The rate of triacylglycerol output from the intestine measured in lymph duct-cannulated animals (kept in a warm box at 30-32 degrees C) was 14.9 +/- 2.7 mumol/hr per rat. Triton treatment of lymph duct-cannulated animals caused only a small increase in plasma triacylglycerol concentration (less than 2 mumol/hr per rat). These data suggest that nearly 100% of plasma triacylglycerol arises from intestinal input in the suckling rat.
mesh_terms: D000828:Animal Population Groups / Q000378:metabolism*; D000818:Animals; D000833:Animals, Suckling / Q000378:metabolism*; D001692:Biological Transport; D004041:Dietary Fats / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008196:Lymph / Q000378:metabolism; D011092:Polyethylene Glycols / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D004041:Dietary Fats; D014280:Triglycerides; D011092:Polyethylene Glycols; C016811:tyloxapol