title: Cutaneous focal mucinosis with spontaneous healing.
abstract: A case of extensive cutaneous focal mucinosis is described. The patient had insulin-dependent diabetes mellitus with complications in the peripheral circulation. No thyroid abnormality was found. The diagnosis was confirmed by typical clinical appearance, by light and electron microscopy. Shortly after the biopsies were taken, clinical healing became evident - a phenomenon which was clearly seen at the ultramicroscopic level. On the basis of the present case, supported by sparse evidence from the literature, it seems probable that cutaneous focal mucinosis does not present a real neoplasm, but a reactive condition with a possibility of spontaneous healing.
mesh_terms: D003560:Cysts / Q000473:pathology; D003937:Diagnosis, Differential; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D008264:Macrophages / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D009232:Myxoma / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
chemical_list: D009077:Mucins