Partial finger loss: an indicator of severe connective tissue disease with overlap features.
Six patients are described with partial finger loss due to severe Raynaud's syndrome. In all cases the vascular changes were an early feature of a connective tissue disease with overlap features. It was a poor prognostic feature often heralding severe multisystem involvement with life threatening and on one occasion fatal consequences.
D000328:Adult; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D005260:Female; D005385:Fingers / Q000098:blood supply; D006801:Humans; D007511:Ischemia / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000175:diagnosis*