title: 2,3-dihydro-4H-1-benzopyran-4-one O-carbamoyloximes, a series of gastric antisecretory agents.
abstract: A series of 2,3-dihydro-4H-1-benzopyran-4-one O-carbamoyloximes were synthesized and evaluated for gastric antisecretory activity in a pylorus-ligated rat model. Various substituents in the 6-position did not afford any compounds more active than I.
mesh_terms: D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D003864:Depression, Chemical; D005750:Gastric Juice / Q000378:metabolism*; D008297:Male; D010091:Oximes / Q000138:chemical synthesis / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001578:Benzopyrans; D010091:Oximes