title: "COLO 357," a human pancreatic adenosquamous carcinoma: growth in artificial capillary culture and in nude mice.
abstract: The human pancreatic cancer cell line COLO 357 has been xenografted s.c. in athymic Swiss mice. The xenografts grew well to form typical adenosquamous carcinomas. The cells were placed in a perfused artificial capillary system where they formed a solid tumor mass which survived for 7 weeks. In this system, the cells consumed glucose and released enzymes and carcinoembryonic antigen into the extracapillary space.
mesh_terms: D000230:Adenocarcinoma / Q000503:physiopathology* / Q000648:ultrastructure; D000818:Animals; D002196:Capillaries / Q000502:physiology; D002294:Carcinoma, Squamous Cell / Q000503:physiopathology* / Q000648:ultrastructure; D002455:Cell Division; D002460:Cell Line; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D008871:Microvilli / Q000648:ultrastructure; D009368:Neoplasm Transplantation; D010190:Pancreatic Neoplasms / Q000503:physiopathology* / Q000648:ultrastructure; D014183:Transplantation, Heterologous