title: On the mechanism of iodination of tyrosine.
abstract: Existing data contain proof that the iodinating species of tyrosine and its derivatives contained in mixtures of iodine and iodide is hypoiodous acid, HOI. It appears likely that the peroxidase-catalyzed iodination reaction with hydrogen peroxide, tyrosine or a tyrosine derivative and either iodide or iodine as substrates involves enzyme-activated HOI.
mesh_terms: D007454:Iodides / Q000378:metabolism; D007455:Iodine / Q000378:metabolism*; D008433:Mathematics; D008956:Models, Chemical; D014443:Tyrosine / Q000378:metabolism*
chemical_list: D007454:Iodides; D014443:Tyrosine; D007455:Iodine