title: Three-dimensional reconstruction of tubulin sheets and re-investigation of microtubule surface lattice.
abstract: Sheets are incomplete microtubule walls observed as polymorphic variants of microtubule assembly. Their substructure is similar to that of microtubules, as shown by two-dimensional optical and computer reconstruction. We have extended earlier studies by computing a three-dimensional reconstruction. From a re-investigation of the surface lattice it appears that the three-start helix of microtubules is right-handed rather than left-handed.
mesh_terms: D000818:Animals; D008854:Microscopy, Electron; D008870:Microtubules / Q000648:ultrastructure*; D008954:Models, Biological; D013552:Swine; D014404:Tubulin
chemical_list: D014404:Tubulin