[Possibilities of using amphoteric surface agents in the campaign against the agents of schistosomiasis transmission].
Among the chemicals which might be used against the larvas of Schistosoma, some surface active substances show some high activity at very low concentrations (0,1-5 ppm) against the miracidiums and the cercariae. The laurylamidopropylbetain has shown out of a group of products which were tested, a very high activity by lowering considerably the infection by the larvas of the hosts, like molluscs and mice, which were in contact with them. After a serie of tests made in Nigeria, these products showed a satisfactory remanence in tropical waters, in spite of the biodegradation and the adsorption on the suspended particles. It was faced to put that betain into soaps at a concentration of 5% which will permit to renew constantly the active product and which will reduce heavily any infection.
D000818:Animals; D001622:Betaine / Q000031:analogs & derivatives* / Q000032:analysis / Q000494:pharmacology; D001700:Biomphalaria / Q000469:parasitology; D006801:Humans; D007814:Larva / Q000187:drug effects; D009548:Niger; D012550:Schistosoma mansoni / Q000187:drug effects*; D012552:Schistosomiasis / Q000517:prevention & control*; D012915:Soaps; D013501:Surface-Active Agents / Q000494:pharmacology*; D014867:Water / Q000032:analysis
D012915:Soaps; D013501:Surface-Active Agents; C034253:laurylamidopropylbetain; D014867:Water; D001622:Betaine
Possibilités d'emploi des agents de surface amphotères dans la lutte contre les agents de transmission des schistosomoses.