[Nodal psammoma body in thyroid cancer as an indicator of cancer metastasis to the lymph node].
A 64-year-old woman underwent subtotal thyroidectomy and cervical lymphadenectomy for thyroid carcinoma. In 5 of 15 resected nodes, histologic examination revealed metastasis. The other 10 nodes showed no metastasis, though psammoma bodies were seen in 3 nodes. To clarify the relationship between psammoma bodies and metastasis, 10 cancer-negative nodes were serially sectioned (4 microns in thickness). This disclosed cancer cells and psammoma bodies in 2 to 3 psammoma body-positive nodes. We suggest that the presence of psammoma bodies in the lymph node may indicate metastasis.
D002291:Carcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy