Atherosclerosis: a molecular disease of membrane fusion.
A working thermodynamic-hysteresis concept, which serves to simplify and clarify the general mechanism behind membrane fusion processes involved in health and disease, is proposed. It is suggested that this concept not only possesses the inherent capacity to answer some fundamental questions involved in Atherosclerosis but also may be even more useful in defining an outline of "Molecular Pathology" for future investigation.
D001161:Arteriosclerosis / Q000209:etiology* / Q000378:metabolism; D001808:Blood Vessels / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D008051:Lipid Bilayers / Q000378:metabolism; D008561:Membrane Fusion; D008563:Membrane Lipids / Q000378:metabolism*; D008823:Micelles; D013816:Thermodynamics
D008051:Lipid Bilayers; D008563:Membrane Lipids; D008823:Micelles