title: Long-acting contraceptive agents: norethisterone esters of arylcarboxylic acids.
abstract: The synthesis of esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxy-estr-4-en-3-one) with acids containing a benzene ring is described, two methods of esterification being compared in terms of yield and convenience. The activities of these esters as long-acting contraceptive agents have been evaluated.
mesh_terms: D002264:Carboxylic Acids; D003692:Delayed-Action Preparations; D004952:Esters; D007202:Indicators and Reagents; D013058:Mass Spectrometry; D009640:Norethindrone / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship
chemical_list: D002264:Carboxylic Acids; D003692:Delayed-Action Preparations; D004952:Esters; D007202:Indicators and Reagents; D009640:Norethindrone