title: [Androgenic function of the adrenal cortex in girl athletes with retarded sexual development].
abstract: Diurnal excretion of 17-ketosteroids and their fractions was studied in 43 girl athletes with retarded sexual development (RSD) and 22 patients who did not go in for sports. Twenty-five healthy girls with a normal menstrual cycle constituted the control group. Athletes with RSD showed relative hyperandrogeny marked by a higher proportion of more active androgenic fractions (dehydroepiandrosterone and androsterone) in total 17-ketosteroids. Excretion of neutral 17-ketosteroids in athletes examined, as compared with non-athletes with RSD, was within age-associated norms or surpassed them. It is suggested that androgens of the adrenal cortex are involved into the pathogenesis of RSD in female athletes.
mesh_terms: D000293:Adolescent; D000309:Adrenal Insufficiency / Q000503:physiopathology*; D000728:Androgens / Q000378:metabolism*; D005260:Female; D006801:Humans; D011628:Puberty, Delayed / Q000209:etiology / Q000503:physiopathology*; D013177:Sports
chemical_list: D000728:Androgens
vernacular_title: Androgennaia funktsiia kory nadpochechnikov u devochek-sportsmenok s zaderzhkoĭ polovogo razvitiia.