title: [Concentration of free amino acids and homocarnosine dipeptide in the cerebrospinal fluid of children with hydrocephalus].
abstract: The content of free amino acids and the dipeptide homocarnosine was examined in the cerebrospinal fluid of children with post-meningitis hydrocephalus. Of 17 identified amino acids the levels of threonine, methionine, leucine, alanine, lysine, histidine, glutamic acid and GABA appeared to be sharply changed. The homocarnosine level in the hydrocephalic children's CSF was found to be 10, and in hydrocephalic children with idiocy, 18 times higher than in the control.
mesh_terms: D000596:Amino Acids / Q000134:cerebrospinal fluid*; D002336:Carnosine / Q000031:analogs & derivatives / Q000134:cerebrospinal fluid*; D002552:Cerebral Ventricles; D002675:Child, Preschool; D004151:Dipeptides / Q000134:cerebrospinal fluid*; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid* / Q000150:complications / Q000209:etiology; D007223:Infant; D008607:Intellectual Disability / Q000150:complications; D008581:Meningitis / Q000150:complications*; D013346:Subarachnoid Space; D005680:gamma-Aminobutyric Acid / Q000134:cerebrospinal fluid
chemical_list: D000596:Amino Acids; D004151:Dipeptides; C005038:homocarnosine; D005680:gamma-Aminobutyric Acid; D002336:Carnosine
vernacular_title: Soderzhanie svobodnykh aminokislot i dipeptida gomokarnozina v likvore deteĭ s gidrotsefalieĭ.