[14C-pentacin pharmacokinetics in percutaneous uptake].
The authors studied the quantitative mechanisms of percutaneous administration and elimination from the body of Na3Ca-14C-diethylene triaminopentacetic acid applied to the skin in 50% dimethyl sulfoxide or in aqueous solution. The data on the time course of the content of the labeled drug in the skin, blood, skeleton, liver, kidneys and urine of rats are provided.
D000818:Animals; D002250:Carbon Radioisotopes; D004121:Dimethyl Sulfoxide / Q000378:metabolism; D007700:Kinetics; D008297:Male; D004369:Pentetic Acid / Q000378:metabolism*; D051381:Rats; D012867:Skin / Q000378:metabolism*; D012996:Solutions; D013997:Time Factors; D014018:Tissue Distribution
D002250:Carbon Radioisotopes; D012996:Solutions; D004369:Pentetic Acid; D004121:Dimethyl Sulfoxide
Farmakokinetika 14Copentatsina pri perkutannom postuplenii.