title: The action of salicylates on bile flow in man.
abstract: Following oral administration of 1.5 g of sodium salicylate or acetylsalicylate to five patients with indwelling T-tubes there was an approximately 50% increase in bile flow. The increase appeared to be in the bile-acid independent fraction of canalicular flow and was not accompanied by a change in lithogenicity. Neither agent would be of use in the medical treatment of cholesterol gallstones.
mesh_terms: D001646:Bile / Q000187:drug effects* / Q000502:physiology; D001647:Bile Acids and Salts / Q000378:metabolism; D002756:Cholagogues and Choleretics / Q000494:pharmacology; D006801:Humans; D050356:Lipid Metabolism; D012459:Salicylates / Q000494:pharmacology*
chemical_list: D001647:Bile Acids and Salts; D002756:Cholagogues and Choleretics; D012459:Salicylates