title: [Therapy of activated gonarthrosis with etofenamate cream (Rheumon cream)].
abstract: In a multicenter single-blind study on 60 patients with unilateral gonarthrosis the efficacy and tolerance of etofenamate cream were compared to a commonly used ointment containing salicylic acid and other ingredients. With respect to therapeutic success etofenamate was superior to the control medication. Mobility and circumference of the knee joint as well as pain parameters improved more rapidly in the etofenamate group, whereby the difference between both groups frequently was statistically significant. With the control medication therapy failed in three cases, with etofenamate cream clinical symptoms improved in all patients. With the exception of a transient local reddening of the skin in one patient of the etofenamate group no adverse drug reactions were observed.
mesh_terms: D000367:Age Factors; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001168:Arthritis / Q000188:drug therapy*; D005260:Female; D005439:Flufenamic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D009824:Ointments
chemical_list: D000893:Anti-Inflammatory Agents; D009824:Ointments; D005439:Flufenamic Acid; C015207:etofenamate
vernacular_title: Therapie der aktivierten Gonarthrose mit Etofenamat-Creme (Rheumon Creme).