A direct anabolic effect of progesterone in the intact female rat.
Rats implanted with progesterone gained weight more rapidly than controls and had a greater percentage of total body fat. The dietary intake of hormone-treated animals was restricted to control levels. The food was supplied in small quantities at regular intervals over a 24-h period with the aid of automatic feeding machines. The observed changes in body weight and composition are therefore not related to either an increased intake of energy or a change in the pattern of feeding after implantation.
D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D004343:Drug Implants; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D050356:Lipid Metabolism; D011374:Progesterone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D004343:Drug Implants; D011374:Progesterone