Analgesic dilemma in chronic hemodialysis patients.
Analgesic drug abuse led to end-stage renal disease in 31% of 122 patients in a cross-sectional investigation at our center. Addiction to analgesics and tranquilizers remained a serious problem in these patients even after they were placed on chronic hemodialysis. There is strong evidence that drug addiction leading to end-stage renal disease and chronic hemodialysis correlates  with a special type of personality typified by the 60-year-old depressive woman suffering from chronic headache.
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000139:chemically induced*; D007681:Kidney Papillary Necrosis / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D010551:Personality; D010615:Phenacetin / Q000009:adverse effects; D006435:Renal Dialysis; D019966:Substance-Related Disorders / Q000150:complications*
D000700:Analgesics; D004338:Drug Combinations; D010615:Phenacetin