title: [First-pass effect as a therapeutic problem].
mesh_terms: D000818:Animals; D001682:Biological Availability; D001711:Biotransformation; D004285:Dogs; D004358:Drug Therapy; D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*
chemical_list: D004364:Pharmaceutical Preparations
vernacular_title: Efekt pierwszego przejścia jako problem terapeutyczny.