title: Keyhole-limpet haemocyanin (KLH) immunotherapy of murine transitional cell carcinoma.
abstract: The antigenicity of transitional cell carcinoma of the bladder has stimulated the search for effective immunotherapeutic agents in the treatment of this disease. Non-specific immunotherapy with local (intravesical/intralesional) and systemic Keyhole Limpet Haemocyanin (KLH) in a FANFT induced murine bladder tumor model was studied. Results showed no difference between control or treated groups in either tumor growth or animal survival.
mesh_terms: D000818:Animals; D000941:Antigens / Q000008:administration & dosage / Q000627:therapeutic use*; D002295:Carcinoma, Transitional Cell / Q000139:chemically induced / Q000276:immunology / Q000628:therapy*; D005200:FANFT; D005260:Female; D006433:Hemocyanins; D007279:Injections, Subcutaneous; D051379:Mice; D008809:Mice, Inbred C3H; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced / Q000276:immunology / Q000628:therapy*
chemical_list: D000941:Antigens; D005200:FANFT; D006433:Hemocyanins; C032808:keyhole-limpet hemocyanin