title: Carcinoma in situ in testicular biopsies from men presenting with infertility.
abstract: This study concerns 2043 male partners of infertile marriages who underwent testicular biopsy in the 28 years from 1955 to 1982. In a review of the pathological material carcinoma in situ (CIS) was diagnosed in 8 men (0.39%). Six of these men were later found to have invasive germ cell tumours; one has remained tumour-free and one is lost to follow-up. The implication of these findings in relation to the selection of patients for biopsy and the treatment of CIS when diagnosed is discussed.
mesh_terms: D000328:Adult; D001706:Biopsy; D002278:Carcinoma in Situ / Q000150:complications* / Q000473:pathology; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology; D013737:Testis / Q000473:pathology