title: [Maternal serum IgA in intrauterine fetal growth retardation].
abstract: The problem was to prove the significance of IgA estimations in maternal serum samples with regard to the diagnosis and the monitoring of intrauterine fetal growth retardation. IgA was estimated in serum samples from two groups of patients. The first was formed from 62 serum samples of 14 primi- and multiparae delivered from new-borns with a birth weight below the 10th centile. The second was the control group. 82 serum samples from 18 gravidae were available. The IgA estimations were carried out by means of single radial immunodiffusion according to Mancini and co-workers. The IgA values of the two groups were different considering that linear regression model was used; negative correlation between IgA and pregnancy weeks in group with retarded new-borns (y = -151,78 X + 7579,8; r = -0,39) and positive correlation of these parameters in control group (y = 73,59 X -429,38; r = 0,26). It could be that IgA is an additional parameter within placental function tests of the 3rd trimester of pregnancy.
mesh_terms: D005260:Female; D005317:Fetal Growth Retardation / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis
chemical_list: D007070:Immunoglobulin A
vernacular_title: Mütterliches Serum-IgA bei intrauteriner fetaler Retardierung.