Improved exercise myocardial perfusion during lidoflazine therapy.
Lidoflazine is a synthetic drug with calcium-channel blocking effects. In a study of 6 patients with severe classic angina pectoris, single-blind administration of lidoflazine was associated with improved myocardial perfusion during exercise as determined by thallium-201 stress scintigraphy. These studies demonstrate that lidoflazine therapy is associated with relief of angina, an increased physical work capacity, and improved regional myocardial perfusion during exercise.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy*; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008013:Lidoflazine / Q000627:therapeutic use*; D008875:Middle Aged; D010477:Perfusion; D005082:Physical Exertion; D010879:Piperazines / Q000627:therapeutic use*; D011868:Radioisotopes; D013793:Thallium
D010879:Piperazines; D011868:Radioisotopes; D013793:Thallium; D008013:Lidoflazine