title: Effective control of a gentamicin-resistant Salmonella arizonae infection in turkey poults.
abstract: A gentamicin-resistant Salmonella arizonae isolate was identified as the cause of an unusually high early mortality rate in several flocks of poults produced by a primary turkey breeder. The company routinely dipped its hatching eggs in 500 ppm gentamicin before incubation and injected each poult at 1 day of age with 1 mg gentamicin. Mortality was reduced to normal, but S. arizonae was not eliminated by injecting the day-old poults with higher doses of gentamicin. S. arizonae was not isolated from sample normal-sized poults in treated groups when tetracyclines were used for antibiotic inoculation of day-old poults. Tetracyclines seemed to be completely effective only when a 5-mg subcutaneous injection per day-old poult was combined with an approximately equal dose in drinking water daily for 4 days, and therapy was accompanied by the culling of runts and other debilitated poults.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002432:Cecum / Q000382:microbiology; D004196:Disease Outbreaks / Q000662:veterinary*; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000494:pharmacology*; D008099:Liver / Q000382:microbiology; D011201:Poultry Diseases / Q000382:microbiology / Q000517:prevention & control*; D012475:Salmonella / Q000187:drug effects*; D012481:Salmonella Infections, Animal / Q000382:microbiology / Q000517:prevention & control*; D012476:Salmonella arizonae / Q000187:drug effects*; D014422:Turkeys
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins