title: An open study of pivampicillin (Pondocillin) as a treatment for acute lower urinary tract infection.
abstract: In a multicentre general practice study 158 females with acute, uncomplicated urinary tract infection received a 5-day course of pivampicillin 500 mg twice-daily (Pondocillin). Significant bacteriological cultures were obtained from forty-one patients before treatment and the original organism was eradicated in thirty-eight of these patients (93%). The mean symptom score was reduced from 7.33 to 1.18. Eleven patients (7%) reported side-effects. One patient ceased treatment after 4 days due to a rash. Pivampicillin, in a convenient twice-daily regimen, was confirmed as an effective treatment for acute lower urinary tract infection.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000031:analogs & derivatives* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008875:Middle Aged; D010917:Pivampicillin / Q000009:adverse effects / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000145:classification / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D010917:Pivampicillin; D000667:Ampicillin