Heredity in anal atresia.
Although anal atresia is known to occur occasionally in families and as part of genetically determined syndromes, the role of genetics in its causation is highly disputable. In this paper evidence is presented for multifactorial genetic determination as the mode of inheritance in anal atresia. This conclusion is argued as based on evidence from the literature as well as findings in an additional series of 48 cases which were collected as a family study.
D001006:Anus, Imperforate / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies