title: Methyl green is a substitute for distamycin A in the formation of distamycin A/DAPI C-bands.
abstract: The DA/DAPI technique has been found to be useful in the identification of specific chromosomal regions on human chromosomes. The realization that distamycin A (DA) is no longer commercially available has necessitated the development of an alternative technique. We describe a technique, MG/DAPI, which substitutes the AT-specific dye methyl green for distamycin A and gives results identical to those of the DA/DAPI technique.
mesh_terms: D002871:Chromosome Banding / Q000379:methods*; D004247:DNA / Q000235:genetics; D004214:Distamycins; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D008739:Methyl Green; D011758:Pyrroles; D012394:Rosaniline Dyes
chemical_list: D004214:Distamycins; D006570:Heterochromatin; D011758:Pyrroles; D012394:Rosaniline Dyes; C030000:stallimycin; D008739:Methyl Green; D004247:DNA