Short-course diphenoxylate hydrochloride for treatment of methadone withdrawal symptoms.
The authors conducted a preliminary trial of a 5-day course of diphenoxylate in the treatment of out-patients with methadone withdrawal symptoms. Diphenoxylate provided substantial relief from detoxification symptoms with no drug-associated adverse effects.
D000328:Adult; D004157:Diphenoxylate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007540:Isonipecotic Acids / Q000627:therapeutic use*; D008297:Male; D008691:Methadone / Q000009:adverse effects*; D010865:Pilot Projects; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*
D007540:Isonipecotic Acids; D004157:Diphenoxylate; D008691:Methadone