title: Extradural morphine for the relief of pain following caesarean section.
abstract: Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of diamorphine 7.5 mg required for pain relief in the first 24 h was 1.93 (+/- 0.30) in the i.m. group and 1.46 (+/- 0.31) in the extradural group. There was a small but definite advantage in the use of the extradural route for the initial dose of morphine. No serious side-effects were noted in either group.
mesh_terms: D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D004824:Epidural Space; D005260:Female; D006801:Humans; D007267:Injections; D007273:Injections, Intramuscular; D009020:Morphine / Q000008:administration & dosage* / Q000627:therapeutic use; D010149:Postoperative Pain / Q000188:drug therapy*; D011247:Pregnancy
chemical_list: D009020:Morphine