[Characteristics of purine and nucleotide metabolism in juvenile rats with alloxan diabetes].
Opposing changes were discovered in the liver and blood of rats aged 1-1 1/2 months with alloxan diabetes as regards the content of adenine, xanthine plus guanine, uric acid and the activity of adenine-, adenosine-, guanine deaminase and 5'-nucleotidase. The ratio of the activity of adenosine deaminase to that of 5'-nucleotidase correlating with the level of glycemia might be the most informative test in the diagnosis of the depth of the discovered metabolic disorders in alloxan diabetes.
D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D011685:Purine Nucleotides / Q000378:metabolism*; D011687:Purines / Q000378:metabolism*; D051381:Rats
D011685:Purine Nucleotides; D011687:Purines; D000496:Alloxan
Osobennosti purinovogo i nukleotidnogo obmena u iuvenil'nykh krys s alloksanovym diabetom.