Chromatographic and spectral properties of some aryl-substituted phencyclidine analogs.
As part of a search for phencyclidine (PCP) antagonists, a series of eleven aryl-substituted PCP analogs were prepared and characterized. TLC and GC elution profiles of these derivatives are described in a number of systems allowing for the tentative identification of the PCP analogs. Further, MS, NMR, UV/vis and IR spectral tabulations are provided. Correlation of chromatographic character with physical organic structure parameters, such as those of Hammet, showed good predictability.
D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D010622:Phencyclidine / Q000031:analogs & derivatives* / Q000032:analysis; D013057:Spectrum Analysis
D010622:Phencyclidine