title: Segmental epidural and subarachnoid analgesia in conscious horses: a comparative study.
abstract: Six adult horses were used to compare the effects of segmental epidural analgesia (SEA) and segmental subarachnoid analgesia (SSA). A 17-gauge Huber point directional needle was used to place a catheter with stylet into the epidural space or the subarachnoid space at the lumbosacral intervertebral junction and to catheterize the thoracolumbar epidural or subarachnoid space. The position of the catheter was confirmed radiographically. A 2% solution of mepivacaine hydrochloride was used at average doses of 80 mg (4 ml) to produce SEA and 30 mg (1.5 ml) to produce SSA. Onset of analgesia in response to superficial and deep muscular pinprick stimulations was significantly (P less than 0.05) faster in horses with SSA than with SEA (8.0 +/- 1.9 minutes vs 15.8 +/- 3.8 minutes). Maximal thoracolumbar analgesia extended from spinal cord segments T14 to L3 on both sides of the spinal column during SSA and from T12 to L2 on one or both sides during SEA. Duration of analgesia lasted significantly (P less than 0.05) longer in horses with SEA than in those with SSA (80.8 +/- 16.9 minutes vs 44.8 +/- 14.5 minutes). There was a significant (P less than 0.05) increase in subcutaneous temperature at the right and left 18th thoracic (T18) dermatomes and decreases of respiratory rate and rectal temperatures in horses with SEA. Respiratory rate and rectal temperature were not significantly (P greater than 0.05) decreased in horses with SSA.(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000698:Analgesia / Q000379:methods / Q000662:veterinary*; D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary; D001794:Blood Pressure; D001831:Body Temperature; D004824:Epidural Space; D005260:Female; D006339:Heart Rate; D006400:Hematocrit / Q000662:veterinary; D006736:Horses / Q000502:physiology*; D007267:Injections / Q000662:veterinary; D008297:Male; D008619:Mepivacaine / Q000008:administration & dosage; D012119:Respiration; D013346:Subarachnoid Space
chemical_list: D008619:Mepivacaine