title: Effect of experimental microvascular orchidopexy on testosterone secretion in the dog.
abstract: This study was undertaken to investigate the endocrine function of the testis that was autotransplanted by microvascular techniques in 10 healthy dogs. After a control period of 4 weeks, hemicastration was carried out, and 4 weeks later the experimental orchidopexy was done. Finally, the transplanted testis was removed after another 4 weeks. Peripheral blood testosterone levels were measured at weekly intervals during the control period, after hemicastration, after autotransplantation and after removal of the transplanted testis. 1 week before each operation, 500 IU human chorionic gonadotrophin (HCG) was given intravenously and the peripheral testosterone levels were determined after 2 and 24 h. During each operation a testicular venous blood sample was taken for testosterone measurements. No differences were found between the basal and HCG-stimulated peripheral plasma levels of testosterone after the hemicastration and the orchidopexy in comparison with the values during the control period. There was a statistically significant positive correlation between the testosterone levels in the testicular venous and peripheral plasma samples. It was concluded that microvascular anastomosis was successful in every case.
mesh_terms: D000818:Animals; D004285:Dogs; D008297:Male; D008866:Microsurgery; D013737:Testis / Q000098:blood supply / Q000637:transplantation*; D013739:Testosterone / Q000097:blood* / Q000378:metabolism; D014656:Vascular Surgical Procedures
chemical_list: D013739:Testosterone