[Effect of methionine-5-enkephalin retroanalog on gastric secretion].
Alteration of the enkephalin molecule by means of synthesis of peptide with opposite direction of peptide connections between residues of aminoacids (retro--methionin--5--enkephalin) entailed some changes of its action in respect to activity of the stomach secretory cells in dogs. Thus, for instance, the retroanalogue methionin--5--enkephalin proved to be a more efficient activator of gastric secretion induced with pentagastrin.
D000818:Animals; D004285:Dogs; D004357:Drug Synergism; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000494:pharmacology; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology; D010418:Pentagastrin / Q000494:pharmacology
D004744:Enkephalin, Methionine; D006632:Histamine; D010418:Pentagastrin
Vliianie retroanaloga metionin-5-enkefalina na sekretsiiu zheludka.