X chromosome replication patterns in a case of X;9 balanced translocation.
A case of X;9 balanced translocation in a female with amenorrhoea is reported. The X breakpoint was at Xq21, inside the 'critical region'. The normal X was consistently late replicating in blood lymphocytes and skin and ovary fibroblasts.
D000328:Adult; D000568:Amenorrhea / Q000235:genetics; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D014178:Translocation, Genetic; D014960:X Chromosome