Prenatal exposure of male mice to androgen increases neuron number in the hypogastric ganglion.
There is a sexual dimorphism in the hypogastric ganglion innervating the internal genitalia of mice. We now report that prenatal exposure of male mice to testosterone propionate brings about a significant increase of neuronal number in the hypogastric ganglion. This suggests that sexually dimorphic nature of the hypograstric ganglion depends on the prenatal hormone environment.
D000818:Animals; D002452:Cell Count; D005260:Female; D005725:Ganglia, Autonomic / Q000187:drug effects*; D005837:Genitalia, Male / Q000294:innervation*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009474:Neurons / Q000166:cytology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012727:Sex Characteristics; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone