CAPD + hemoperfusion once a week in the management of children with end-stage renal disease.
With hemoperfusion there is a sharp decline in the solute concentration of the blood compartment, but immediately after HP the concentration of these substances rises to the original level (post-Hp rebound). It may be inferred that the result would be better and the rebound phenomenon less marked if hemoperfusion could be combined with a continuous dialysis system such as CAPD. The study was performed in 3 children of our CAPD program. All patients were dialysed with 5 daily exchange each of one liter. The patients underwent at 2-hours hemoperfusion with a charcoal column (Gambro Adsorba 150 c) once a week. The data obtained with this form of treatment are indicative for a: significant increase of weekly clearance for uric acid and creatinine. low urea generation rate far 1-3 days after HP. low post-Hp rebound and reduced platelet count but not platelet activation.
D002648:Child; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy*; D008297:Male; D010530:Peritoneal Dialysis; D010531:Peritoneal Dialysis, Continuous Ambulatory; D014527:Uric Acid / Q000378:metabolism
D014527:Uric Acid; D003404:Creatinine