[Fibrinolytic and thrombolytic properties of a plasminogen activator isolated from the culture broth of calf kidney cells].
Plasminogen activator isolated from cultural liquid of calf renal cells is an enzyme having a fibrinolytic action in vitro and in vivo, provoking a demonstrable thrombolytic effect, which depends on the drug dose, thrombus size and animal's body weight.
D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D004353:Drug Evaluation, Preclinical; D005337:Fibrin / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D066298:In Vitro Techniques; D007601:Jugular Veins; D007668:Kidney / Q000201:enzymology*; D010960:Plasminogen Activators / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D013927:Thrombosis / Q000188:drug therapy
D005343:Fibrinolytic Agents; D005337:Fibrin; D010960:Plasminogen Activators
Fibrinoliticheskie i tromboliticheskie svoĭstva aktivatora plazminogena, vydelennogo iz kul'tural'noĭ zhidkosti kletok pochki teliat.