Interaction of human erythrocyte acetylcholinesterase with lectins.
Interaction of acetylcholinesterase (A ChE) of human erythrocyte membranes with wheat germ lectin, Concanavalin A, Lens Culinaris lectin and phytohaemagglutinin is described. In solutions containing Triton X 100, only Wheat Germ lectin showed significant binding with AChE. Sepharose-immobilized Wheat Germ lectin bound AChE significantly more than Concanavalin A. This interaction was used for partial purification of the enzyme.
D000110:Acetylcholinesterase / Q000097:blood*; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D003208:Concanavalin A / Q000494:pharmacology; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D037102:Lectins / Q000494:pharmacology*; D014909:Wheat Germ Agglutinins
D002800:Cholinesterase Inhibitors; D037102:Lectins; D014909:Wheat Germ Agglutinins; D003208:Concanavalin A; D000110:Acetylcholinesterase