title: Simultaneous on-line measurement of blood K+, Ca2+, Na+, and pH with a four-function ChemFET integrated-circuit sensor.
abstract: On-line, simultaneous measurement of blood K+, Ca2+, Na+, and pH has been achieved by using a quadruple-function ChemFET (chemical-sensitive field-effect transistor) integrated-circuit sensor. Blood is withdrawn from the subject through an actively heparinized, dual-lumen cannula and passed into a flow-cell containing the sensor, in alternation with a calibration solution. A minicomputer controls the analysis system, logs data, and provides a continuous, graphic display of K+ and pH values.
mesh_terms: D001322:Autoanalysis; D002118:Calcium / Q000097:blood*; D002408:Catheters, Indwelling; D003201:Computers; D004563:Electrochemistry / Q000295:instrumentation*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008838:Microcomputers; D011188:Potassium / Q000097:blood*; D012964:Sodium / Q000097:blood*
chemical_list: D012964:Sodium; D011188:Potassium; D002118:Calcium