title: Onset-offset effects of the human brainstem auditory-evoked response.
abstract: Brainstem auditory-evoked responses (BSAER's) were obtained from 4 normal-hearing young adults to a 2-kc/s tonal stimulus of 2-, 3-, 4-, 5-, 6-, 7- or 8-msec duration at 60 db sensation level. Latency of Jewett Wave V was recorded averaging 4096 sweeps; stimuli had a 1-msec rise-fall time, with a 65-msec interstimulus interval. A Wave V response to the onset transient was present for all durations. For stimulus durations of less than 5 msec no reliable offset response was noted. Latency measures indicated the onset response to be much less variable than the offset response. The onset response latency of Wave V remained stable over a stimulus duration range of 2-8 msec. The BSAER of a single S demonstrated the intrasubject variability of the offset response as a function of stimulus duration.
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D001299:Audiometry / Q000379:methods*; D001300:Audiometry, Evoked Response / Q000295:instrumentation / Q000379:methods*; D001933:Brain Stem / Q000502:physiology*; D005072:Evoked Potentials, Auditory; D006801:Humans; D008297:Male; D011930:Reaction Time; D013997:Time Factors