title: Adherence of mouse macrophages to plastic lens implants--resulting in the formation of a cellular membrane.
abstract: An experiment for the study of the adherence of mouse macrophages to lens implants under tissue culture conditions has been developed. Formation of a continuous monolayer of cells on the surface of a plastic implant after 18 hours of incubation is demonstrated when this is exposed to a fluid with a high concentration of macrophages. Fewer macrophages in a thin fluid layer on the surface of a tissue culture dish made of clear plastic under the same conditions also showed adherence in a noncontinuous pattern. Some of these macrophages adherent to the surface of the plastic dish resembled reactive cell types that have previously been seen on lens implants removed from human eyes.
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D046508:Culture Techniques; D007910:Lenses, Intraocular; D008264:Macrophages / Q000166:cytology*; D008566:Membranes; D051379:Mice; D010969:Plastics
chemical_list: D010969:Plastics