beta-Phenylethylamine-, d-amphetamine-and l-amphetamine-induced place preference conditioning in rats.
The conditioned place preference paradigm was used to study the reinforcing properties of beta-phenylethylamine (PEA), d-amphetamine and l-amphetamine. The results confirmed that each drug produced place preferences for a distinctive environment that had previously been paired with the drug treatment. PEA proved as effective as the amphetamine isomers, although substantially less potent. This is the first report of a reinforcing effect of PEA in the rat and supplements previous evidence that PEA is self-administered intravenously in the dog.
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D003213:Conditioning, Psychological / Q000187:drug effects*; D003913:Dextroamphetamine / Q000494:pharmacology; D004777:Environment; D006801:Humans; D008297:Male; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats; D012054:Reinforcement, Psychology; D013239:Stereotyped Behavior / Q000187:drug effects
D010627:Phenethylamines; C029261:phenethylamine; D000661:Amphetamine; D003913:Dextroamphetamine