title: Psychological evaluation of treated females with virilizing congenital adrenal hyperplasia.
abstract: The psychological development of females with congenital adrenal hyperplasia (CAH) has been previously studied by Money, et al, who found that psychological development of sex identity was consistent with sex assignment despite virilizing adrenal hormones and abnormal external genitalia requiring surgical correction. In this study, using a variety of psychological tests, we assessed the sex-dimorphic behavior, body image, cognitive functioning, and sex-role identity of nine patients ranging in age from 13 to 21, all treated with glucocorticoids and surgical correction. Four of the nine showed moderate virilization despite treatment. Psychological measures included the Wechsler Intelligence Scale for Children-Revised (WISC-R), the Bem Sex-Role Inventory, the Draw-A-Person (DAP) and an interview with patient and family. Results indicate that patients fall within the normal expectable range for this developmental period in visual-spatial and verbal cognitive functioning, in sex-role identity, and in social interpersonal early behaviors. In two areas of functioning these patients demonstrated some variance from the norms, specifically in sexual identity and early activity levels. This suggests that sexual identity and physical activity are most prone to hormonal and psychological impact but that cognition and sex-role identity are not affected. Future studies of this sample will look at personality dimensions such as ego functioning, defense and affect to consider the impact of body image concerns and conflicts.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000312:Adrenal Hyperplasia, Congenital / Q000523:psychology* / Q000628:therapy; D000328:Adult; D001828:Body Image; D002987:Clitoris / Q000601:surgery; D003071:Cognition; D003131:Combined Modality Therapy; D005260:Female; D005783:Gender Identity; D006801:Humans; D007361:Intelligence Tests; D007406:Interview, Psychological; D011581:Psychological Tests; D014770:Virilism / Q000523:psychology / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones