title: [Methodological survey of erythrocyte filtration time].
abstract: We measured the whole blood filtration time of 30 healthy subjects. The influence of hematocrit, fibrinogen, leucocyte and platelet count on filtration time was also evaluated. Multiple regression analysis did not demonstrate any effect of the above-mentioned parameters when they were separately considered. We have subsequently taken from the entire population a group of 14 subjects in which were simultaneously found values of hematocrit greater than or equal to 41%, fibrinogen greater than or equal to 210 mg/100 ml and platelet count greater than or equal to 250,000/mm3. The filtration time was significantly higher in this group (69 +/- 4 sec) than in the remaining 16 normal subjects (56 +/- 4 sec), p less than 0.05. These data suggest that the simultaneous variation of several parameters could modify the whole blood filtration time, while these parameters have no effect when taken separately.
mesh_terms: D000328:Adult; D001769:Blood; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006400:Hematocrit; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D010976:Platelet Count; D013997:Time Factors; D014462:Ultrafiltration / Q000379:methods*
chemical_list: D005340:Fibrinogen
vernacular_title: Rilievi metodologici sul tempo di filtrazione eritrocitaria.