Mathematical analysis of antiserum titre and affinity in rabbits injected with 11 alpha OH-progesterone-hemisuccinate-BSA.
A mathematical procedure is presented here to determine the behaviour of antiserum titre in rabbits, after repeated injections of 11 alpha OH-Progesterone-hemisuccinate-BSA. By means of methods recently applied to the time series, the peaks of maximum response were determined. A common behaviour of rabbits was revealed for the delay times in the response after each booster injection. The titre and affinity of antiserum were determined by means of a special method for mathematical treatment of data in RIA analysis, which gives directly such parameters with a statistical interpretation.
D000818:Animals; D000915:Antibody Affinity; D005260:Female; D006908:Hydroxyprogesterones / Q000276:immunology*; D007106:Immune Sera / Q000032:analysis* / Q000276:immunology; D007114:Immunization; D007700:Kinetics; D011817:Rabbits; D011863:Radioimmunoassay; D012710:Serum Albumin, Bovine / Q000276:immunology*; D013223:Statistics as Topic
D006908:Hydroxyprogesterones; D007106:Immune Sera; D012710:Serum Albumin, Bovine; C030250:progesterone 11-hemisuccinate