Hyperplastic fundic gland polyp of the stomach.
A case of a solitary pedunculated gastric polyp occurring in the fundic mucosa of a 47-year-old woman is reported because of its unique morphology. The polyp showed a peculiar lobulated configuration supported by smooth muscle bundles, and its epithelial component was composed mainly of a proliferation of relatively normal but disorganized fundic glands containing variable numbers of mucous, parietal, argyrophile, and chief cells. Although these histologic features may suggest a hamartoma-like quality, the lesion probably represents a peculiar form of localized hyperplastic process of the gastric mucosa exhibiting fundic glandular cell differentiation.
D005260:Female; D005748:Gastric Fundus / Q000473:pathology; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*