title: Cefoperazone in the treatment of osteomyelitis.
abstract: Twenty-six patients (aged 20 to 78 years) with osteomyelitis of the lower extremity (22) and infections of the spine (4) were treated with the broad-spectrum antibiotic cefoperazone. Staphylococcus aureus was the major pathogen isolated. A complete cure was obtained in 18 (69.2%) of the 26 patients treated; an additional four patients (15.4%) demonstrated a satisfactory clinical result without complete eradication of all baseline pathogens.
mesh_terms: D000328:Adult; D000368:Aged; D002438:Cefoperazone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy*; D010384:Pelvic Bones; D013131:Spine; D013203:Staphylococcal Infections / Q000188:drug therapy*
chemical_list: D002438:Cefoperazone