title: Prevalence of hyperprolactinaemia and galactorrhoea in secondary amenorrhoea.
abstract: Using Commercial R.I.A. Kits, plasma prolactin levels have been assayed in 41 Nigerian women with secondary amenorrhoea and in 10 normal ovulating women. The prolactin levels were 34.5 +/- 28.9 ng/ml and 14 +/- 6.8 ng/ml respectively; these prolactin levels differed significantly (p less than 0.001). Fifteen amenorrhoeic women had prolactin levels exceeding 28 ng/ml while no normal women had such prolactin levels. The highest prolactin levels, greater than 100 ng/ml were in the two patients with pituitary tumours. The relative frequency of galactorrhoea in patients with secondary amenorrhoea was 19.5%. The results of this study are comparable with those obtained in Caucasians.
mesh_terms: D000568:Amenorrhea / Q000097:blood* / Q000453:epidemiology; D005260:Female; D005687:Galactorrhea / Q000097:blood*; D006801:Humans; D007775:Lactation Disorders / Q000097:blood*; D009549:Nigeria; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*
chemical_list: D011388:Prolactin