Bromocriptine induced hypoprolactinemia and accessory reproductive glands response to testosterone in castrated male rats.
Testosterone stimulates the Accessory Reproductive Glands (ARG) and may increase the serum titres of prolactin in castrated male rats. Bromocriptine antagonizes the testosterone-induced alteration of ARG responses; the testosterone antagonistic action of bromocriptine depends on the degree of serum prolactin depletion.
D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology*; D002369:Castration; D005837:Genitalia, Male / Q000033:anatomy & histology / Q000187:drug effects*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D011388:Prolactin / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods; D051381:Rats; D011919:Rats, Inbred Strains; D013739:Testosterone / Q000494:pharmacology*
D001971:Bromocriptine; D013739:Testosterone; D011388:Prolactin