Anti-triiodothyronine autoantibodies interfere with two recently commercialized radioimmunoassays for free triiodothyronine.
We examined the effect of anti-triiodothyronine autoantibodies on results of RIA of free triiodothyronine with two commercial kits (Amersham International and Diagnostic Products Corp.). Both methods gave falsely high results because the 125I-labeled analogs used in these RIAs were bound by the autoantibodies.
D001323:Autoantibodies / Q000276:immunology*; D005189:False Positive Reactions; D006801:Humans; D011863:Radioimmunoassay / Q000379:methods; D011933:Reagent Kits, Diagnostic; D014284:Triiodothyronine / Q000032:analysis* / Q000276:immunology
D001323:Autoantibodies; D011933:Reagent Kits, Diagnostic; D014284:Triiodothyronine