The human Klüver-Bucy syndrome.
Twelve patients with the Klüver-Bucy syndrome (KBS) are described. The syndrome occurred in head trauma, Alzheimer's disease, Pick's disease, and following herpes encephalitis. KBS was transient after head trauma but was a persistent feature of the postencephalitic syndrome. In all cases KBS was combined with aphasia, amnesia, or dementia. Human KBS resembles the monkey syndrome, but in humans there is a more elaborate complex of behavioral disturbances. The behavioral manifestations are produced by bilateral temporal lobe dysfunction. Partial expression of the syndrome may have localizing validity.
D000328:Adult; D001037:Aphasia / Q000503:physiopathology; D001519:Behavior / Q000502:physiology*; D001927:Brain Diseases / Q000503:physiopathology*; D003704:Dementia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000503:physiopathology; D008875:Middle Aged; D012725:Sexual Behavior / Q000502:physiology*; D013577:Syndrome; D013702:Temporal Lobe / Q000503:physiopathology