title: [Autoradiographic and cytophotometric study of DNA synthesis in the oocytes of the domestic hen at the preleptotene prophase stage of meiosis].
abstract: 3H-thymidine incorporation into the fowl oocytes was established radioautographically at the middle preleptotene, when chromosomes are condensed and associated in the complex chromocenters. According to the cytophotometry of Feulgen stained oocyte nuclei, their DNA value increases during preleptotene from 2 to 4c. So, the DNA synthesis observed is characteristic of chromosome reduplication, rather than of nuclear organizer amplification. The preleptotene should be considered as the initial stage of meiotic prophase because it involves spiralization and individualization of chromosomal threads. Both the analysis of literary data and of our own results enable us to conclude that in different species the meiotic chromosome reduplication may proceed in different periods between telophase of last gonial mitosis and the beginning of homologous chromosome conjugation.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002642:Chick Embryo; D004247:DNA / Q000032:analysis / Q000096:biosynthesis*; D005260:Female; D008540:Meiosis; D009865:Oocytes / Q000166:cytology / Q000378:metabolism*; D010783:Photometry; D011418:Prophase; D013997:Time Factors
chemical_list: D004247:DNA
vernacular_title: Avtoradiograficheskoe i tsitofotometricheskoe issledovanie sinteza DNK v ootsitakh domashneĭ kuritsy na predleptotennoĭ stadii profazy meĭoza.