Effect of oral CDP-choline on experimental withdrawal syndrome.
The effect of an oral treatment with cytidine diphosphate choline (CDP-choline, citicoline, Somazina) on experimental withdrawal syndrome is studied. Two different methods have been used and both of them resulted in a decreasing intensity of withdrawal syndrome.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D051379:Mice; D009021:Morphine Dependence / Q000523:psychology; D009270:Naloxone / Q000494:pharmacology; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*; D013997:Time Factors
D009270:Naloxone; D003566:Cytidine Diphosphate Choline; D002794:Choline