Focal cerebral ischemia and mitral valve prolapse in monozygotic twins.
Mitral valve prolapse (MVP) is a common frequently inherited cardiac valvular disorder. Ischemic cerebrovascular disease (ICVD) is an apparent complication of MVP. We report the concordance of MVP and ICVD in a pair of monozygotic twins. This occurrence reinforces the concepts that MVP is highly concordant in monozygotic twins and that it can be the cause of familial ICVD.
D002545:Brain Ischemia / Q000209:etiology* / Q000235:genetics; D005260:Female; D006801:Humans; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000150:complications* / Q000235:genetics; D011247:Pregnancy; D014427:Twins; D014430:Twins, Monozygotic