[Effect of experimental hyperphenylalaninemia on the metabolism of gluco- and galactocerebrosides and sulfatides].
Alterations in content of gluco- and galactocerebrosides were studied in brain of rats of various age. Specific radioactivity of glucocerebrosides exceeded distinctly that of galactocerebrosides. When chronic hyperphenylalaninemia was produced in adult rats, the specific radioactivity of brain cerebrosides and sulfatides decreased significantly. Content of these glycolipid fractions decreased only slightly in liver and spleen tissues.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002554:Cerebrosides / Q000378:metabolism*; D005699:Galactosylceramides / Q000378:metabolism*; D005963:Glucosylceramides / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D010649:Phenylalanine / Q000097:blood*; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013433:Sulfoglycosphingolipids / Q000378:metabolism*
D002554:Cerebrosides; D005699:Galactosylceramides; D005963:Glucosylceramides; D013433:Sulfoglycosphingolipids; D010649:Phenylalanine
Vliianie éksperimental'noĭ giperfenilalaninemii na metabolizm gliuko-, galaktotserebrozidov i sul'fatidov.