[Technic of isolated perfusion of the extremities. Experience with 171 cases].
In 171 cases of isolated perfusion of the extremities for treatment of melanomas and soft tissue sarcomas, standardized operation techniques were perfected. The arterial double cannulation makes an iliac cannulation feasible also in cases of second and third perfusion. Cytostatics are dosed per liter of perfused extremity. Cis-Platinum and dacarbacine were recently introduced in isolation perfusion treatment. So-called preheating of the extremity before adding the drugs allows administration of cytostatics besides tumortoxic hyperthermia.
D001132:Arm; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D002945:Cisplatin / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005112:Extracorporeal Circulation; D006801:Humans; D006979:Hyperthermia, Induced; D007866:Leg; D008466:Mechlorethamine / Q000008:administration & dosage; D008545:Melanoma / Q000188:drug therapy; D008558:Melphalan / Q000008:administration & dosage; D011182:Postoperative Care; D012983:Soft Tissue Neoplasms / Q000188:drug therapy
D008466:Mechlorethamine; D003606:Dacarbazine; D002945:Cisplatin; D008558:Melphalan
Technik der isolierten Extremitätenperfusion. Erfahrungen an 171 Fällen.