title: [Diagnostic and therapeutic problems in endangiitis obliterans].
abstract: Out of all patients (n = 313) suffering from peripheral vascular disorders seen at our Department from 1975 to 1981 21 patients had Buerger's disease (Thrombendangitis obliterans). In 4 of them immunological deposits could be traced in the basement membrane of their capillaries. In our opinion nicotine has a stimulating immunological effect on the vessel wall and can be considered as the trigger mechanism for Buerger's disease.
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D001158:Arteries / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation; D008297:Male; D012907:Smoking; D013300:Streptokinase / Q000627:therapeutic use; D013562:Sympathectomy; D013919:Thromboangiitis Obliterans / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D014656:Vascular Surgical Procedures
chemical_list: D013300:Streptokinase
vernacular_title: Diagnostische und therapeutische Probleme bei der Endangitis obliterans.