Congenital Budd-Chiari syndrome.
Budd-Chiari syndrome, due to thrombotic occlusion of hepatic veins or ostia, is unusual in infants. Review of the literature reveals no documented case symptomatic at birth. We describe a male infant with ascites present at birth. A liver biopsy at 7 weeks of age showed sinusoidal dilatation, but the diagnosis of Budd-Chiari syndrome was made only at autopsy, 4 months later. The cause was not determined although maternal drug abuse was suspected.
D001201:Ascites / Q000151:congenital / Q000209:etiology; D006502:Budd-Chiari Syndrome / Q000150:complications / Q000151:congenital* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology; D008297:Male