title: Absence of shock-like reactions to ivermectin in dogs infected with Dirofilaria immitis.
abstract: Six dogs infected with Dirofilaria immitis and known to develop shock-like reactions after administration of diethylcarbamazine (DEC) were given ivermectin 50 micrograms/kg orally. None of the dogs showed any adverse reaction and subsequently all reacted to DEC 20 mg/kg orally.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004049:Diethylcarbamazine / Q000627:therapeutic use; D004184:Dirofilariasis / Q000188:drug therapy*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D007559:Ivermectin; D007783:Lactones / Q000627:therapeutic use*; D012772:Shock, Septic / Q000139:chemically induced
chemical_list: D000871:Anthelmintics; D007783:Lactones; D007559:Ivermectin; D004049:Diethylcarbamazine