title: [Conservative and surgical therapy of vesicoureterorenal reflux].
abstract: The pathogenesis of reflux nephropathy and morbidity is discussed first, then chances of spontaneous maturation and risks for scarring are compared with resulting guidelines for conservative and operative treatment. A list of indications is proposed regarding grade of reflux, age, essential diagnostic parameters (VC, cystoscopy, IVP), history and other clinical aspects. Over and above this, an "ephedrine-test" developed at Erlangen in 1976 is described with regard to possible adrenergic treatment of primary reflux. Results of over 500 Gregoir-Lich procedures from 1963 to 1976 are presented with rates of stenosis (0-2%) and failure (4.3-5.2%), complications and persistence of infection. Finally, a short review is presented of the morphology and management of secondary reflux (associated with infravesical obstruction).
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004809:Ephedrine; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000517:prevention & control; D008297:Male; D011704:Pyelonephritis / Q000209:etiology; D014718:Vesico-Ureteral Reflux / Q000150:complications / Q000601:surgery / Q000628:therapy*
chemical_list: D004809:Ephedrine
vernacular_title: Konservative und operative Therapie des vesikoureterorenalen Refluxes.