[Effect of starch-induced structural and functional modification in a population of free phagocytes on antibody formation induction by ram erythrocytes in mice].
The influence of the starch-induced modification of the population of free phagocytes on the induction of antibody formation by sheep red blood cells (SRBC) in mice has been studied. The intraperitoneal injection of starch has been shown to render a pronounced modulating effect on immune response stimulated by the intramuscular injection of the antigen. The injection of a small dose of SRBC into the abdominal cavity enriched with starch-stimulated monocytes is accompanied by an increase in immune response; this phenomenon is not observed after immunization with a large dose of the antigen. Starch-stimulated macrophages, when introduced with SRBC into syngeneic recipients, show stimulating influence on immune response.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D007114:Immunization; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010538:Peritonitis / Q000139:chemically induced / Q000276:immunology; D010586:Phagocytes / Q000187:drug effects* / Q000276:immunology; D012756:Sheep / Q000276:immunology; D013213:Starch / Q000276:immunology*; D013997:Time Factors
D013213:Starch
Vliianie vyzvannoĭ krakhmalom strukturnoĭ i funktsional'noĭ modifikatsii populiatsii nefiksirovannykh fagotsitov na induktsiiu antitelogeneza éritrotsitami barana u mysheĭ.