[Imadyl: gastric irritation in comparison with acetylsalicylic acid, indomethacin, piroxicam and diclofenac-Na].
A study on 10 healthy male volunteers with the new non-steroidal antiphlogistic drug Carprofen is reported. Carprofen was tested versus Aspirin, Indomethacin, Piroxicam, and Diclofenac-Na using the model of measuring the gastric transmural potential difference (GPD). The lowest values of the relevant parameters concerning the gastric irritation were measured after administration of Carprofen.
D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects; D002227:Carbazoles / Q000009:adverse effects*; D004008:Diclofenac / Q000009:adverse effects; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D010894:Piroxicam; D013270:Stomach / Q000187:drug effects* / Q000502:physiology; D013843:Thiazines / Q000009:adverse effects
D000893:Anti-Inflammatory Agents; D002227:Carbazoles; D013843:Thiazines; D010894:Piroxicam; D004008:Diclofenac; C007005:carprofen; D001241:Aspirin; D007213:Indomethacin
Imadyl(R): Die gastrische Irritation im Vergleich zu Acetylsalicylsäure, Indometacin, Piroxicam und Diclofenac-Na.