Combined local chemotherapy for a spontaneously occurring intraocular tumour in a cat.
A spontaneously occurring tumour in the anterior chamber of the eye of a cat was diagnosed by aspiration needle biopsy as a malignant lymphosarcoma. Combined local chemotherapy, consisting of subconjunctival injection of methylprednisolone acetate and methotrexate along with topical administration of dexamethasone, led to rapid resolution of the lesion. Over 18 weeks of follow-up there was no recurrence.
D015065:17-Hydroxycorticosteroids / Q000008:administration & dosage; D000287:Administration, Topical; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D004359:Drug Therapy, Combination; D005134:Eye Neoplasms / Q000188:drug therapy / Q000662:veterinary*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage
D015065:17-Hydroxycorticosteroids; D000970:Antineoplastic Agents; D008727:Methotrexate