title: Flexibility and rigidity of left-handed Z-DNA.
abstract: The local variation of torsional angles and helical parameters in Z-DNA was analyzed. The sugar phosphate backbone is fairly rigid but the angles at GpC linkage are more changeable than those at CpG linkage in order to form a variety of structures. The water channel at minor groove is important to stabilize and retain the novel Z-DNA helix.
mesh_terms: D004247:DNA; D009038:Motion; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA