[Effect of the transplantation of heterochronic thymus on the development of immunological reactivity in CBA mice. 2. Transplantation to intact animals].
The effect of transplantation of thymus from donors of different age on the immune system development was studied in the newborn CBA mice. The thymuses of 22 month and 5 day old donors were shown to exert different effects: accelerated (early attainment of the plateau) and decelerated (late attainment of the peak) maturation of the immune system in the recipients. This fact is discussed with respect to interaction of transplanted and host thymuses.
D000818:Animals; D000831:Animals, Newborn; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000276:immunology; D006087:Graft vs Host Reaction; D007111:Immunity, Cellular; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA / Q000276:immunology*; D013950:Thymus Gland / Q000637:transplantation*; D013997:Time Factors; D014181:Transplantation Immunology
Vliianie peresadki geterokhronnogo timusa na stanovlenie immunologicheskoĭ reaktivnosti u mysheĭ CBA. 2. Transplantatsiia intaktnym zhivotnym.