title: Effects of oxygen concentration on biomass production, maximum specific growth rate and extracellular enzyme production by three species of cutaneous propionibacteria grown in continuous culture.
abstract: Propionibacterium acnes, Propionibacterium avidum and Propionibacterium granulosum were grown in continuous culture at 0-100% air saturation using a semi-synthetic medium. Maximum specific growth rate, biomass concentration and extracellular lipase, hyaluronate lyase and phosphatase activities were determined. All three species were capable of growth at 100% air saturation but at reduced growth rates. The presence of oxygen altered the production of extra-cellular enzymes. Propionibacterium avidum was the best adapted for growth in aerobic environments.
mesh_terms: D000135:Acid Phosphatase / Q000096:biosynthesis; D001426:Bacterial Proteins / Q000096:biosynthesis; D004463:Ecology; D006801:Humans; D008049:Lipase / Q000096:biosynthesis; D010100:Oxygen / Q000494:pharmacology*; D011133:Polysaccharide-Lyases / Q000096:biosynthesis; D011424:Propionibacterium / Q000201:enzymology / Q000254:growth & development*; D011425:Propionibacterium acnes / Q000201:enzymology / Q000254:growth & development; D011489:Protein Denaturation; D012867:Skin / Q000382:microbiology*; D013045:Species Specificity
chemical_list: D001426:Bacterial Proteins; D008049:Lipase; D000135:Acid Phosphatase; D011133:Polysaccharide-Lyases; C100002:hyaluronate lyase; D010100:Oxygen