The influence of adrenaline on plasma testosterone in adult and newborn male rats.
In adult male intact and adrenalectomized rats a significant decrease of plasma testosterone was found following five days of subcutaneous treatment with adrenaline. LH was significantly decreased in adrenalectomized, adrenaline treated males. Plasma testosterone was also found to be diminished in the male offspring of females treated with adrenaline during pregnancy. In view of these findings catecholamines may also play a role in the stress-induced drop of plasma testosterone in adult animals as well as in the production of androgen deficiency in male fetuses and newborns of stress-exposed pregnant females.
D000315:Adrenalectomy; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000097:blood*; D004837:Epinephrine / Q000494:pharmacology*; D005260:Female; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D007986:Luteinizing Hormone; D004837:Epinephrine