Disseminated intravascular coagulation complicating systemic juvenile chronic arthritis ("Still's disease").
Two children suffering from systemic juvenile chronic arthritis (JCA) complicated by acute disseminated intravascular coagulation (DIC) are described. One had a fatal outcome with acute renal failure and cerebral haemorrhage; the other recovered. Early recognition and treatment of the underlying cause - usually an infection - as well as replacement of clotting factors are important in management.
D001171:Arthritis, Juvenile / Q000150:complications*; D001241:Aspirin / Q000009:adverse effects; D002648:Child; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D005260:Female; D006192:Haemophilus Infections / Q000150:complications; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects; D008297:Male
D001241:Aspirin; D007213:Indomethacin