title: [Immunoglobulins in man. Biological properties and therapeutic aspects].
abstract: The therapy with (modified) immune serum globulin implies critical limitation of therapeutic indications as well as the knowledge of the biological and physical properties of the immunoglobulin preparations. While the therapeutic effect in prophylaxis and substitution therapy is well established, the benefit has still to be proven for the therapy of severe acute infections. The predominant role of antibodies in the defense against bacterial and some viral infections encourages for the use of immune serum globulin in acute infections.
mesh_terms: D000917:Antibody Formation; D000936:Antigen-Antibody Complex; D001792:Blood Platelets; D003165:Complement System Proteins; D006801:Humans; D007116:Immunization, Passive; D007128:Immunoglobulin Fragments; D007136:Immunoglobulins; D008214:Lymphocytes; D010587:Phagocytosis; D018805:Sepsis / Q000188:drug therapy
chemical_list: D000936:Antigen-Antibody Complex; D007128:Immunoglobulin Fragments; D007136:Immunoglobulins; D003165:Complement System Proteins
vernacular_title: Immunoglobulin vom Menschen. Biologische Eigenschaften und therapeutische Aspekte.