Metabolism of carbohydrate in vitro of the submandibular salivary glands (SMG) from mice injected with isoproterenol.
The effect of a single dose of isoproterenol, a beta-adrenergic drug, on the metabolism of carbohydrate in vitro of SMG from mice was studied. At the end of 30 and 60 min of incubation the slices of SMG from the experimental groups, sacrificed from 2 to 18 hr after injection of IPR, presented higher glucose uptake. At the end of 60 min of incubation slices of SMG from mice injected with IPR and sacrificed from 2 to 28 hr after the stimulation, formed quantitatively more lactate. After the incubation periods in the presence of glucose, glycogen content was higher for the SMG from the experimental groups.
D000818:Animals; D050260:Carbohydrate Metabolism; D005947:Glucose / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D007545:Isoproterenol / Q000494:pharmacology*; D007773:Lactates / Q000096:biosynthesis; D019344:Lactic Acid; D008297:Male; D051379:Mice; D010101:Oxygen Consumption / Q000187:drug effects; D013363:Submandibular Gland / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors
D007773:Lactates; D019344:Lactic Acid; D006003:Glycogen; D005947:Glucose; D007545:Isoproterenol