Membranous glomerulopathy and chronic small-intestinal enteropathy associated with autoantibodies directed against renal tubular basement membrane and the cytoplasm of intestinal epithelial cells.
A child with an immune-mediated disease is described, who presented two very rare clinical manifestations, a membranous glomerulopathy with circulating anti-renal tubular basement membrane antibody and a small-intestinal enteropathy with circulating antibody directed against the cytoplasm of intestinal epithelial cells. Steroid treatment was followed by complete resolution of the renal but not the intestinal manifestations.
D001323:Autoantibodies / Q000032:analysis*; D001485:Basement Membrane / Q000276:immunology; D002675:Child, Preschool; D002908:Chronic Disease; D003593:Cytoplasm / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007410:Intestinal Diseases / Q000276:immunology*; D007421:Intestine, Small / Q000276:immunology / Q000473:pathology; D007684:Kidney Tubules / Q000276:immunology; D008297:Male; D009404:Nephrotic Syndrome / Q000276:immunology*
D001323:Autoantibodies; D007136:Immunoglobulins