Aryl hydrocarbon hydroxylase activity and psoriasis.
Aryl hydrocarbon hydroxylase (AHH) has been measured in the skin, jejunum and liver of normal and psoriatic individuals. We have been unable to confirm previous reports of an abnormality in AHH activity in patients with psoriasis. Re-examination of the laboratory records on which the original reports were based leads us to doubt their veracity and validity.
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000302:isolation & purification*; D001551:Benz(a)Anthracenes / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D007583:Jejunum / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D011565:Psoriasis / Q000201:enzymology*; D012867:Skin / Q000201:enzymology; D013379:Substrate Specificity
D001551:Benz(a)Anthracenes; C030935:benz(a)anthracene; D001189:Aryl Hydrocarbon Hydroxylases