Relative changes in bile secretion during rat liver regeneration.
The influences of partial hepatectomy (66%) on some aspects of rat biliary secretion were studied at different time intervals after surgery (0, 40, 96, 192 and 384 h). Bile salt independent and bile salt dependent fractions were determined. During the first intervals (40 and 96 h) bile salt independent fraction clearly decreased after which it slowly recovered (192 h) until control levels were reached (384 h). These results are interpreted as proof of a faster compensatory hyperplastic regeneration in zone I of the hepatic acinus than in zone III.
D000818:Animals; D001646:Bile / Q000032:analysis / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000032:analysis; D005260:Female; D006498:Hepatectomy; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D011184:Postoperative Period; D051381:Rats; D013997:Time Factors
D001647:Bile Acids and Salts