Comparison of sotalol and propranolol in mild to moderate essential hypertension.
The controlled, open, cross-over study reported in this article demonstrates that sotalol and propranolol administered twice daily to 20 patients provide an equally satisfactory control of moderately elevated blood-pressure for 24 hours. The average daily dose of sotalol and propranolol required to achieve this effect was 200 +/- 95 mg and 154 +/- 90 mg respectively. No important side-effects were observed.
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D004341:Drug Evaluation; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use*; D013015:Sotalol / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
D011433:Propranolol; D013015:Sotalol