Prenatal toxic effects of STS 557. I. Investigations in mice.
STS 557 was tested for adverse effects in mice by prenatal and postnatal investigations. Several doses of STS 557 and levonorgestrel as a standard were administered on days 3--7, 8--12, or 13--17 post coitum. Following administration on days 3--7 p.c. an increase of skeleton retardations and skeleton alterations was found.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004622:Embryo, Mammalian / Q000187:drug effects*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D051379:Mice; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000633:toxicity; D011247:Pregnancy; D045167:Progesterone Congeners / Q000633:toxicity*; D013723:Teratogens
D045167:Progesterone Congeners; D013723:Teratogens; C023635:dienogest; D009277:Nandrolone