Effect of timolol on the movement of water in the anterior chamber of the rabbit eye.
In the anterior chamber of the rabbit eye the following were determined: the rate of appearance, the inflow and the outflow of water under control condition and after pretreatment with timolol 0.5% ophthalmic solution. In the aqueous humor HCO3(-), Na+, K+ content and pH was determined. Results suggest that timolol acts on the inflow (production) of aqueous humor.
D000818:Animals; D000867:Anterior Chamber / Q000378:metabolism*; D001082:Aqueous Humor / Q000187:drug effects / Q000378:metabolism*; D001639:Bicarbonates / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011817:Rabbits; D012964:Sodium / Q000378:metabolism; D013999:Timolol / Q000494:pharmacology*
D001639:Bicarbonates; D013999:Timolol; D012964:Sodium; D011188:Potassium