title: Muscle beta-actinin inhibits elongation of the pointed end of the actin filaments of brush border microvilli.
abstract: By using isolated actin bundles of brush border microvilli of chicken intestinal epithelial cells, it was clearly visualized that muscle beta-actinin caps the pointed end of an actin filament, whereas cytochalasin D masks the barbed end. The growth rate at the barbed end in the presence of beta-actinin was markedly slower than in its absence.
mesh_terms: D000185:Actinin / Q000302:isolation & purification*; D000199:Actins / Q000378:metabolism*; D000818:Animals; D002645:Chickens; D004848:Epithelium / Q000648:ultrastructure; D007422:Intestines / Q000648:ultrastructure*; D007700:Kinetics; D008854:Microscopy, Electron; D008871:Microvilli / Q000378:metabolism / Q000648:ultrastructure*; D009124:Muscle Proteins / Q000302:isolation & purification*; D009132:Muscles / Q000502:physiology; D011817:Rabbits
chemical_list: D000199:Actins; D009124:Muscle Proteins; D000185:Actinin