[A controlled study on the effects of nomifensine treatment of depression in the elderly].
After a description of the pharmacological and therapeutic properties of Nomifensine, the results obtained by administering the drug to 40 elderly patients suffering from depression are reported. A double blind test with a placebo was conducted in two separate stages. Dosage was 70-75 mg per diem. Effects were evaluated on a slightly modified Plutchik scale. The drug alleviated depressive symptoms to a statistically significant greater degree than the placebo. Subjective side effects were minimal. No A.P. or biohumoral changes were observed.
D000368:Aged; D003863:Depression / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009627:Nomifensine / Q000627:therapeutic use*
D007546:Isoquinolines; D009627:Nomifensine
Studio controllato sugli effetti della nomifensina nel trattamento della depressione dell'anziano.