[Platelet aggregation inhibition with calcium dobesilate].
In 52 patients with pathologically increased platelet aggregation the effect of a 4-day oral treatment of 500 mg, 1000 mg and 1500 mg calcium dobesilate (Dexium 500) on spontaneous platelet aggregation was assessed using PAT III of Breddin. In comparison to placebo 1500 mg calcium dobesilate reduced platelet aggregation significantly, 1000 mg and 500 mg calcium dobesilate, however, didn't influence platelet aggregation.
D000328:Adult; D000368:Aged; D000375:Aging; D001557:Benzenesulfonates / Q000494:pharmacology*; D002123:Calcium Dobesilate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D012737:Sex Factors
D001557:Benzenesulfonates; D002123:Calcium Dobesilate
Thrombozytenaggregationshemmung unter Calciumdobesilat.