Computer methodology for simulation and prediction of alloimmune responses: expected antibody specificities.
The methodology presented here was developed for simulating planned alloimmunization results, with regard to the type and number of expected antibody specificities. The computer program designed for this purpose was adapted to an immunogenetic model using Boolean algebra. It was written to help immunogeneticists avoid handling routine data preceding selection of donor-recipient pairs, specially concerning blood type alloimmunizations in animals: all of the donor-recipient combinations and the expected antibody specificities (their limit number being specified in each particular immunization program) are provided in the print-out.
D000818:Animals; D000829:Animals, Domestic; D000918:Antibody Specificity; D001789:Blood Group Antigens / Q000276:immunology; D001788:Blood Grouping and Crossmatching; D002417:Cattle; D003201:Computers; D007114:Immunization; D007125:Immunogenetics; D007518:Isoantibodies / Q000096:biosynthesis*; D008954:Models, Biological
D001789:Blood Group Antigens; D007518:Isoantibodies