title: [Syntheses of 14C-1-erythro-norephedrine and its N-substitution products 14C-oxyfedrine and 14C-D 13,625].
abstract: Starting from 14C-benzene (--)-erythro-norephedrine (14C-1-norephedrine) was obtained in a 6-step synthesis. 14C-1-Norephedrine functioned as an intermediate for the synthesis of the carbon labelled partial beta-agonist oxyfedrine hydrochloride (ildamen) and the new positive inotropic agent D 13 625 (alifedrine hydrochloride).
mesh_terms: D002250:Carbon Radioisotopes; D055598:Chemical Phenomena; D002621:Chemistry; D007553:Isotope Labeling; D010099:Oxyfedrine / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D010665:Phenylpropanolamine / Q000138:chemical synthesis*; D011427:Propiophenones / Q000138:chemical synthesis*
chemical_list: D002250:Carbon Radioisotopes; D011427:Propiophenones; D010665:Phenylpropanolamine; D010099:Oxyfedrine; C039523:alifedrine
vernacular_title: Synthesen von 14C-1-erythro-Norephedrin sowie seiner N-Substitutionsprodukte 14C-Oxyfedrin und 14C-D 13 625.