title: [Panhypopituitarism in one of 2 monozygotic twins].
abstract: Anterior panhypopituitarism has been observed in one of monozygous twin girls. Etiologic investigations were negative and only suggested an hypothetic perinatal insult. Genetic abnormalities could be excluded. Replacement therapy with human growth hormone was strikingly successful, with a remarkable catch-up growth and, however, a velocity of bone age comparable with the velocity of growth.
mesh_terms: D000365:Age Determination by Skeleton; D002675:Child, Preschool; D004200:Diseases in Twins; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy; D014430:Twins, Monozygotic
chemical_list: D013006:Growth Hormone
vernacular_title: Panhypopituitarisme chez l'une de deux jumelles monozygotes.