[Potentiation of the antitumor activity of dioxadet by antiestrogen para-aminobenzhydrazide in a model of ovarian ascites tumor].
Experiments on rats with transplantable ascitic tumor of the ovary showed an antiestrogen--para-aminobenzhydrazide--to potentiate the antitumor effect of dioxadet. The mechanism of para-aminobenzhydrazide action is discussed.
D000814:Aniline Compounds / Q000008:administration & dosage*; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001201:Ascites / Q000188:drug therapy / Q000473:pathology; D004195:Disease Models, Animal; D004357:Drug Synergism; D005260:Female; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D014227:Triazines / Q000008:administration & dosage*
D000814:Aniline Compounds; D000970:Antineoplastic Agents; D014227:Triazines; C034343:4-aminobenzhydrazide; C040269:dioxadet
Potetntsirovanie protivoopukholevogo deĭstviia dioksadéta antiéstrogenom--paraaminobenzgidrazidom na modeli astsitnoĭ opukholi iaichnika.