[Chromosome aberrations and sister chromatid exchanges in the chromosomes of the blood lymphocytes of rats after iodine-131 incorporation into the body].
Mutagenic effect of iodine-131 was studied in vivo by the analysis of chromosome aberrations (Chr.A.) and sister chromatid exchanges (SCE) frequencies in peripheral blood lymphocytes in white rats. Incorporated iodine-131 induced Chr.A. and increased the SCE frequency. A great quantity of the former was preserved for a long period of time after a single introduction of iodine-131 into the body of rats, the latter being increased with reducing dose rate and decreasing the number of Chr.A.
D000818:Animals; D002869:Chromosome Aberrations; D003434:Crossing Over, Genetic / Q000528:radiation effects*; D007457:Iodine Radioisotopes / Q000378:metabolism*; D008214:Lymphocytes / Q000528:radiation effects / Q000648:ultrastructure*; D008297:Male; D008677:Metaphase / Q000528:radiation effects; D051381:Rats; D012854:Sister Chromatid Exchange / Q000528:radiation effects*; D013997:Time Factors
D007457:Iodine Radioisotopes
Khromosomnye aberratsii i sestrinskie khromatidnye obmeny v khromosomakh limfotsitov krovi krys posle inkorporirovaniia v organizme ĭoda-131.