Hyperactivity in rats following postnatal anoxia.
A model of hyperactive rats was produced by exposing pups to severe anoxia within 24 h following birth. These rats demonstrated augmented motor activity in ambulation, sniffing and rearing activities in an open field. Activity was significantly increased at 10 days of age, maximal at 20-25 days and returned to normal values around 6 weeks of age.
D000818:Animals; D000831:Animals, Newborn; D001238:Asphyxia Neonatorum / Q000150:complications*; D001289:Attention Deficit Disorder with Hyperactivity / Q000209:etiology*; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors