title: Compensation of the low-pass filter properties of the current measuring internode in potential-clamped myelinated nerve fibres.
abstract: The bandwidth of membrane current measurements in potential-clamped Ranvier nodes is limited by the low-pass filter properties of the internodes. If about 35% of the current measuring internode is grounded via an additional electrode, the bandwidth of this internode increases by a factor of about 40. Consequently, in potential clamp experiments the measured time course of the early ionic currents changes markedly, while the duration of the capacity current is shortened.
mesh_terms: D000818:Animals; D004566:Electrodes; D004594:Electrophysiology / Q000295:instrumentation; D066298:In Vitro Techniques; D009186:Myelin Sheath / Q000502:physiology*; D009474:Neurons / Q000378:metabolism*; D011901:Ranvier's Nodes / Q000502:physiology; D014982:Xenopus laevis