title: The effects of neonatal androgenization of female hamsters on adult preference for female hamster vaginal discharge.
abstract: The effects of neonatal exposure of hamsters to androgen on the development of an adult preference for female hamster vaginal discharge (FHVD) were investigated. Three groups treated on Days 2-3 postpartum (females administered testosterone propionate (TP) in a peanut oil base, females administered oil alone, and males administered oil alone) were combined factorially with four sequential adult conditions (intact, post-gonadectomy, post-gonadectomy plus TP therapy, and post-gonadectomy) to produce twelve experimental conditions. Statistical analysis indicated that neonatal oil females did not show a significant FHVD preference in any adult condition. Neonatal TP females displayed a significant FHVD preference only in the post-gonadectomy plus TP condition. Males retained a significant FHVD preference in all the adult conditions, although the preference shown in the two adult hormonal conditions (intact and post-gonadectomy plus TP) was significantly higher than the preference shown in the two nonhormonal conditions.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002369:Castration; D006224:Cricetinae; D005260:Female; D008297:Male; D008647:Mesocricetus; D012724:Sex Attractants; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D012903:Smell / Q000187:drug effects*; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D012724:Sex Attractants; D013739:Testosterone