title: Effect of supplemented magnesium from magnesium oxide or dolomitic limestone upon digestion and absorption of minerals in sheep.
abstract: Three metabolism trials were conducted with six lambs fitted with abomasal and ileal cannulae to determine the site of supplemental Mg absorption when supplied as dolomitic limestone or magnesium oxide. Magnesium intake was 1.09 g/d for the lambs fed the control diet and 2.21 and 2.10 g for those fed the dolomitic limestone and magnesium oxide supplemented diets, respectively. Irrespective of its source, the major site of Mg absorption was the preintestinal region. Magnesium was secreted in the small intestine in lambs fed all three diets. Magnesium supplementation resulted in an increase (P less than .05) in preintestinal Mg absorption, with magnesium oxide having the highest value. Supplementation had no effect (P greater than .05) on secretion or absorption of Mg from the small and large intestines or total retention of Mg. With all three diets, the major site of Ca absorption was the stomach region with additional absorption taking place in the large intestine. Calcium was secreted in the small intestine of lambs fed all treatments. Generally, K, Na and P were secreted in the preintestinal region and absorbed from the small and large intestines. The major site of K and P absorption appeared to be the small intestine and for Na, the large intestine. Serum minerals were unchanged (P greater than .05) due to treatment, but the levels of Mg, K and inorganic P tended to be higher in lambs supplemented with either of the Mg sources. It appears that the greater utilization of Mg from magnesium oxide vs dolomitic limestone is due to greater absorption of Mg from the forestomach region.
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D002119:Calcium Carbonate / Q000008:administration & dosage; D004032:Diet; D004063:Digestion / Q000187:drug effects; D007408:Intestinal Absorption / Q000187:drug effects; D008274:Magnesium / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D008277:Magnesium Oxide / Q000008:administration & dosage; D008297:Male; D008903:Minerals / Q000378:metabolism*; D010758:Phosphorus / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism
chemical_list: D008903:Minerals; D010758:Phosphorus; D008277:Magnesium Oxide; D012964:Sodium; D002119:Calcium Carbonate; D008274:Magnesium; D011188:Potassium; D002118:Calcium; C028042:calcium magnesium carbonate