IgG-rheumatoid factor in a population of elderly males: relationship to IgM-rheumatoid factor and rheumatoid arthritis.
The occurrence of IgG-rheumatoid factor (RF) reacting with rabbit IgG was studied in the sera of 1,105 elderly males from rural areas of Finland. Elevated levels of IgG-RF were found in 12 sera, 11 of which contained also IgM-RF, as measured by conventional agglutination tests and/or by enzyme-linked immunosorbent assay. Subjects with rheumatoid arthritis and those with "false" positive RF reactions did not differ from each other with respect to the occurrence of IgG-RF.
D000328:Adult; D000372:Agglutination Tests; D000818:Animals; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005387:Finland; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007841:Latex Fixation Tests; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis*; D012424:Rural Population; D012756:Sheep / Q000276:immunology
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D012217:Rheumatoid Factor