K-region oxidized metabolites of 9-hydroxybenzo[a]pyrene.
Synthesis is described of the methyl ether of 9-hydroxybenzo[a]pyrene 4,5-oxide, previously implicated as a metabolite of benzo[a]pyrene which binds covalently to nucleic acids in vivo.
D001580:Benzopyrenes / Q000378:metabolism*; D001711:Biotransformation; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
D001580:Benzopyrenes; C021337:9-hydroxybenzo(a)pyrene