[Changes in the contraction of the smooth muscle of the rat portal vein during emotional stress].
Effect of emotional/painful stress on contractile function and adrenoreactivity of rat portal vein was examined. Tension developed by portal vein of stress-exposed animals was shown to be reduced 8-fold as compared to that of the controls; tension development and relaxation velocities were decreased 4.4- and 6-fold, respectively. The changes were accompanied by a significant decrease in stress-exposed animals' venous response to norepinephrine and by enhanced sensitivity to calcium shortage and glucose depletion in washing solutions. Possible stress-induced damage of calcium-transport membrane mechanism and its role in the occurrence of arterial hypovolemia are discussed.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003470:Culture Media; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008297:Male; D009119:Muscle Contraction; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology*; D009638:Norepinephrine / Q000502:physiology; D011169:Portal Vein / Q000503:physiopathology; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000503:physiopathology*; D013696:Temperature
D003470:Culture Media; D005947:Glucose; D002118:Calcium; D009638:Norepinephrine
Narushenie sokratitel'noĭ funktsii gladkoĭ muskulatury vorotnoĭ veny krys pri émotsional'no-bolevom stresse.