Treatment of non-invasive amoebiasis. A comparison between tinidazole alone and in combination with diloxanide furoate.
Tinidazole (40 mg/kg body-weight in one daily dose for five days) and tinidazole (same dose) plus diloxanide furoate (20 mg/kg body-weight divided into three daily doses for 10 days) were compared as treatments for amoebiasis. The parasitic cure rates were 44 and 91% respectively. We cannot, therefore, recommend tinidazole alone in this dosage as a treatment for non-invasive amoebiasis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000562:Amebiasis / Q000188:drug therapy*; D000563:Amebicides / Q000627:therapeutic use*; D002648:Child; D004359:Drug Therapy, Combination; D005663:Furans / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D009593:Nitroimidazoles / Q000627:therapeutic use*; D014011:Tinidazole / Q000627:therapeutic use*
D000563:Amebicides; D005663:Furans; D009593:Nitroimidazoles; D014011:Tinidazole; C004932:diloxanide furoate