[Clinical and biological significance of the correlation between glycosylated hemoglobin, blood uric acid and blood triglycerides].
An example of the correlations between sugar, fat and protein metabolisms is presented and discussed. The example is taken from a group of patients subjected to outpatient metabolic tests, among whom a sub-group was found to have a higher glycosylated haemoglobin level due to unusually high levels of uricaemia and triglyceridaemia (P less than 0.001). Alcohol abuse, common to all these patients, may explain the simultaneous increase in uricaemia and triglyceridaemia, while the increase in Hb A1, might be caused dy the hyperinsulinism provoked by the first two. Altogether these alterations may put the patients at serious risk of atherogenesis, especially considering the role of insulin in regulating the fat metabolism of the arterial wall.
D000328:Adult; D000437:Alcoholism / Q000097:blood* / Q000378:metabolism; D001161:Arteriosclerosis / Q000209:etiology; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D006946:Hyperinsulinism / Q000209:etiology; D050356:Lipid Metabolism; D008875:Middle Aged; D012306:Risk; D014280:Triglycerides / Q000097:blood*; D014527:Uric Acid / Q000097:blood*
D001786:Blood Glucose; D002784:Cholesterol; D006442:Glycated Hemoglobin; D014280:Triglycerides; D014527:Uric Acid
Significato clinico e biologico della correlazione tra emoglobina glicosilata, uricemia e trigliceridemia.