Comparison of folate levels in convulsing and non-convulsing febrile children.
The relationship between folic acid levels and occurrence of convulsion in febrile subjects was studied in thirty-two children aged 8 months to 5 years. Both the serum and red cell folate levels were significantly higher in the febrile children who convulsed than in those who did not convulse. When the period of convulsion was more than thirty minutes, there was a significant rise in the red cell folate. These results suggest that the accumulation of folate in the serum and red cell may be causally related to the development of the convulsing state in febrile children.
D001831:Body Temperature; D002675:Child, Preschool; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D005492:Folic Acid / Q000097:blood* / Q000134:cerebrospinal fluid; D006801:Humans; D007223:Infant; D008297:Male; D012640:Seizures / Q000097:blood* / Q000134:cerebrospinal fluid; D003294:Seizures, Febrile / Q000097:blood* / Q000134:cerebrospinal fluid; D013997:Time Factors
D005492:Folic Acid