title: [Antibiotic therapy in severe infections].
abstract: The problems of selecting antibiotics for hospital use from the broad variety offered, and the problems of what is often necessarily a non-specific initial therapy, are discussed. A review is given of groups of antibiotics which are important for hospital therapy such as penicillins, aminoglycosides, metronidazole and cephalosporins. Firstly the range of effects of the individual groups of antibiotics is summarized in a simplified form from which the indications are then derived. In discussing the clinical use of antibiotics special importance is attached to initial therapy prior to or in the absence of identification of the pathogens in fatal infectious diseases. From this aspect the therapy for pneumonia, peritonitis, sepsis and urosepsis as well as meningitis is discussed. The small number of indications for the prophylactic use of antibiotics is briefly dealt with. Finally a selection of antibiotics necessary for hospital therapy is presented.
mesh_terms: D000617:Aminoglycosides / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy; D002511:Cephalosporins / Q000627:therapeutic use; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D008581:Meningitis / Q000188:drug therapy; D008795:Metronidazole / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D010538:Peritonitis / Q000188:drug therapy; D011014:Pneumonia / Q000188:drug therapy
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins; D008795:Metronidazole
vernacular_title: Antibiotikatherapie bei schweren Infektionen.