title: [Genetic control of tryptophan hydroxylase activity in the mouse brain].
abstract: Interstrain differences in tryptophan hydroxylase activity have been studied in the brain stem of 12 inbred strains of mice. The Mendelian analysis has been performed using BALB/c and C57BL/6J mice. The activity of tryptophan hydroxylase was shown to be controlled by a single gene having two alleles with additive effect. It was suggested that this gene controls either the structure of enzyme's molecule, or its amount in a nervous tissue.
mesh_terms: D000483:Alleles; D000818:Animals; D001921:Brain / Q000201:enzymology*; D001933:Brain Stem / Q000201:enzymology; D005809:Genes, Regulator; D006824:Hybridization, Genetic; D007700:Kinetics; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013045:Species Specificity; D014365:Tryptophan Hydroxylase / Q000235:genetics*
chemical_list: D014365:Tryptophan Hydroxylase
vernacular_title: Geneticheskiĭ kontrol' aktivnosti triptofangidroksilazy v golovnom mozge mysheĭ.