A study of platelet aggregation and adhesion in gout.
Platelet aggregation and adhesion were measured in twelve male patients with gout. Tests were performed with the patients off all treatment for six weeks and after the serum uric had been lowered with allopurinol. Results of aggregation and adhesion tests were normal and not influenced by the uric acid level. The increased cardiovascular disease risk in gout is unlikely to be due to an increased thrombotic tendency.
D000328:Adult; D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use; D006073:Gout / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D010979:Platelet Function Tests; D013997:Time Factors; D014527:Uric Acid / Q000097:blood
D014527:Uric Acid; D000493:Allopurinol