[Reaction of neurons in the arcuate hypothalamic area to the microiontophoretic application of serotonin at different stages of the estrous cycle in rats].
Among the neurons of the hypothalamic arcuate area, the center of tonic regulation of gonadotropic function, prevailed those with activating response to serotonin at the dioestrus-2 stage of the oestrus cycle, particularly in the morning hours. During prooestrus, an increased number of neurons with inhibitory responses was found, especially during evening hours. Serotonin induced a decrease in the amount of luteinizing hormone in the blood which was usually combined with an activating action of the indolamine on the neuronal activity. The combination of the neurotransmitter inhibitory effect on the spontaneous neuronal activity in the arcuate nucleus with the decrease of amount of the luteinizing hormone in the blood was mostly observed at the prooestrus stage only.
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000187:drug effects*; D004971:Estrus; D005260:Female; D007478:Iontophoresis; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D010902:Pituitary Gland / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology*
D012701:Serotonin; D007986:Luteinizing Hormone
Reaktsiia neĭronov arkuatnoĭ oblasti gipotalamusa na mikroionoforeticheskoe podvedenie serotonina v razlichnye stadii éstral'nogo tsikla u krys.