Effect of ethacrynate sodium on transmesothelial transfer of solutes.
The effect of ethacrynate sodium on transmesothelial fluxes of solutes was studied in vitro. Ethacrynate sodium increased the mesothelial permeability to urea, chloride and sodium. The increase was transient, reproducible and not dependent on cellular metabolism.
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002712:Chlorides / Q000378:metabolism; D004976:Ethacrynic Acid / Q000494:pharmacology*; D007082:Ileum; D008643:Mesentery / Q000187:drug effects*; D011817:Rabbits; D012964:Sodium / Q000378:metabolism; D014508:Urea / Q000378:metabolism
D002712:Chlorides; D014508:Urea; D012964:Sodium; D004976:Ethacrynic Acid