[Measurement of cytoplasmic androgen receptor in compensatory renal hypertrophy in the rat].
In order to determine whether kidney hypertrophy secondary to unilateral nephrectomy was an appropriate model to study cytoplasmic androgen receptor modulation, this receptor was measured three weeks after surgery in intact or castrated animals. Our results demonstrate that the process of kidney hypertrophy is not accompanied by a proportional elevation of the number of androgen receptors and that these receptors are not significantly influenced by the gonadal activity in the rat.
D000818:Animals; D002369:Castration; D006984:Hypertrophy; D007668:Kidney / Q000032:analysis* / Q000473:pathology; D008297:Male; D009392:Nephrectomy; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D011944:Receptors, Androgen / Q000032:analysis*; D011987:Receptors, Steroid / Q000032:analysis*; D013739:Testosterone / Q000378:metabolism
D011944:Receptors, Androgen; D011987:Receptors, Steroid; D013739:Testosterone
Mesure du récepteur cytoplasmique des androgènes au cours de l'hypertrophie rénale compensatrice chez le rat.