Hepatic microsomal mixed-function oxidases in rats exposed to high ambient temperature.
Exposure of rats for 3 h or 6h to 28 degrees C or 37 degrees C led to changes in mixed-function oxidases in liver microsomes as compared with 21 degrees C. The complex pattern of the behaviour of the activities of aniline hydroxylase, 4-nitroanisole-O-demethylase, aminopyrine N-demethylase and NADH: cytochrome c oxidoreductase was not related to the observed decrease of cytochrome P-450 and cytochrome b5 contents.
D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000815:Aniline Hydroxylase / Q000378:metabolism; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003573:Cytochrome b Group / Q000378:metabolism; D015786:Cytochromes b5; D006358:Hot Temperature; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009245:NADH Dehydrogenase / Q000378:metabolism; D009575:Nitroanisole O-Demethylase / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism; D051381:Rats
D003573:Cytochrome b Group; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D009575:Nitroanisole O-Demethylase; D010105:Oxygenases; D000815:Aniline Hydroxylase; D000633:Aminopyrine N-Demethylase; D009245:NADH Dehydrogenase