[Effect of ionizing radiation on the functional state of the vascular-thrombocytic component of the hemostasis system].
The influence of ionizing radiation (gamma-rays 60Co) on aggregation activity of the vascular wall and functional (aggregation) platelet activity was studied in the course of the development of acute radiation sickness. The decrease in the aggregation properties of the vascular wall and high functional activity of platelets were inversely proportional, correlating with the periods of acute radiation sickness development and depending on the radiation dose. It is suggested that the changes detected may play a role in the pathogenesis of the development of the postirradiation thrombohemorrhagic syndrome.
D000818:Animals; D001808:Blood Vessels / Q000503:physiopathology*; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D006168:Guinea Pigs; D010974:Platelet Aggregation / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains
D003037:Cobalt Radioisotopes
Vliianie ioniziruiushchego izlucheniia na funktsional'noe sostoianie sosudisto-trombotsitarnogo zvena sistemy gemostaza.