title: Ultrastructural studies on synaptic formations in dissociated fetal mouse brain cultures.
abstract: Sequential electron microscopic studies of cultures of neurons derived from dissociated fetal mouse brain on the eleventh day of gestation revealed the formation of well-developed synapses during the second and third weeks of growth in vitro. Synaptic junctions were associated with synaptic vesicles nd dense synaptic membranes. Dense-core vesicles were also observed frequently in presynaptic terminals.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology*; D002454:Cell Differentiation; D046508:Culture Techniques; D051379:Mice; D008854:Microscopy, Electron; D009474:Neurons / Q000166:cytology; D013569:Synapses / Q000648:ultrastructure*; D013572:Synaptic Vesicles / Q000648:ultrastructure