title: Evoked potential studies of the effects of impact acceleration on the motor nervous system.
abstract: The initial results of a continuing investigation into the effects of various levels of impact acceleration on the functional integrity of the motor nervous system are summarized. The results are based on the measurement of alterations in neural transmission along the motor pathway of the Rhesus monkey as revealed by latency and amplitude changes in the motor pathway evoked potential (EP) following the delivery of various levels of impact acceleration to a test vehicle. The EPs were produced by electrical stimulation of and recording from the motor pathway of experimental animals subjected to -Y (lateral impact) acceleration and animals subjected to -X (frontal impact) acceleration. High resolution latency and amplitude measures of the EP recorded from these animals before and after impact were tracked so that the time course of recovery of nerve propagation following impact could be accurately assessed. Analysis of these EP measures revealed that the time course of recovery to preimpact values is directly related to the intensity of the acceleration impulse delivered to the test vehicle.
mesh_terms: D000054:Acceleration / Q000009:adverse effects*; D000818:Animals; D004569:Electroencephalography; D005071:Evoked Potentials; D008253:Macaca mulatta / Q000502:physiology; D008905:Minicomputers; D009046:Motor Neurons / Q000502:physiology*; D009424:Nervous System Physiological Phenomena; D009431:Neural Conduction; D011187:Posture; D013997:Time Factors