Paroxysmal language disturbance in an epileptic treated with clobazam.
An 18-year-old male student had a 3-month history of partial seizures with cognitive symptomatology, with occasional secondary generalization. After 3 weeks of treatment with clobazam 20 mg a day, the patient developed, in association with his seizures, a neologistic jargon dysphasia but with loss of inflection, volume, and rhythm of speech, presumably as a result of the effect of the clobazam.
D000293:Adolescent; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000009:adverse effects* / Q000627:therapeutic use; D000078306:Clobazam; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D008297:Male; D013064:Speech Disorders / Q000139:chemically induced* / Q000523:psychology
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D001569:Benzodiazepines; D000078306:Clobazam