Idiopathic intestinal pseudo-obstruction and contaminated small bowel syndrome--treatment with metronidazole, ileostomy, and indomethacin.
A 28-year-old Iranian man with chronic idiopathic intestinal pseudo-obstruction presented with gross features of contaminated bowel syndrome. Treatment with metronidazole reversed steatorrhea but exacerbated the gaseous distention of the small intestine, precipitating emergency surgical decompression and ileostomy. A chronic high volume ileostomy diarrhea ensued and was successfully treated with oral indomethacin.
D000328:Adult; D001835:Body Weight; D003248:Constipation / Q000209:etiology; D006801:Humans; D007081:Ileostomy; D007213:Indomethacin / Q000627:therapeutic use*; D007415:Intestinal Obstruction / Q000601:surgery*; D007418:Intestinal Pseudo-Obstruction / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D007421:Intestine, Small / Q000382:microbiology*; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*
D008795:Metronidazole; D007213:Indomethacin