title: Stimulatory effects of prostaglandin F2 alpha on faecal egg production in Haemonchus contortus infected sheep.
abstract: The effect of prostaglandin F2 alpha on the pattern of faecal egg count was tested in 10- to 12-month-old sheep infected with 20,000 Haemonchus contortus larvae. Prostaglandin was infused intravenously 25, 50 and 75 days after infection for four hours at a rate of 5 micrograms/kg/minute and the egg counts in the faeces were determined daily for 110 days. Treatment on days 50 and 75 was followed by a significant rise in egg count lasting 19 and 12 days respectively. This observed rise seems to be related to a resumption of development of arrested larvae induced by prostaglandin treatment, and a hypothesis is proposed to explain its initiation.
mesh_terms: D000818:Animals; D005243:Feces / Q000469:parasitology; D005260:Female; D006188:Haemonchiasis / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects*; D010063:Ovum / Q000187:drug effects*; D010270:Parasite Egg Count; D011460:Prostaglandins F / Q000494:pharmacology*; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology; D014251:Trichostrongyloidea / Q000187:drug effects*; D014252:Trichostrongyloidiasis / Q000662:veterinary*
chemical_list: D011460:Prostaglandins F