Sexual precocity in a boy due to hypersecretion of LH and prolactin by a pituitary adenoma.
The paper reports on precocious puberty and galactorrhoea in a 4 8/12 year old boy. Roentgenograms of the skull showed slight lateral bulging of sella floor and pneumoencephalography indicated a pituitary adenoma with a suprasellar extension. Pre-operative study of anterior pituitary function was normal except for increased values of LH (900 mIU/ml), testosterone (2000 ng/ml) and prolactin (215 ng/ml). After removal of a chromophobe pituitary adenoma by transfrontal surgery the galactorrhoea disappeared within 10 days. Post-operative endocrine evaluation showed immediate normalization of LH, testosterone and prolactin values.
D000236:Adenoma / Q000378:metabolism* / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D005687:Galactorrhea / Q000209:etiology; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000601:surgery; D011011:Pneumoencephalography; D011247:Pregnancy; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D011629:Puberty, Precocious / Q000209:etiology*; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone