title: The effect of repeated administration of L-thyroxine on the activity of certain enzymes in the blood plasma of hens.
abstract: Studies on the influence of long-lasting hyperthyroidism on enzyme activities and total protein level in the blood plasma of adult Leghorn hens showed that: 1. Protein level during whole experimental period showed inconsiderable variability irrespective of T4 dose. 2. Activity of aspartate aminotransferase (GOT) and alanine aminotransferase (GPT) increased. Changes were dependent on T4 dosage level. 3. T4 had no effect on activity of aldolase.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D002645:Chickens / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood*; D007457:Iodine Radioisotopes; D013961:Thyroid Gland / Q000502:physiology; D013974:Thyroxine / Q000502:physiology*
chemical_list: D007457:Iodine Radioisotopes; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D005634:Fructose-Bisphosphate Aldolase; D013974:Thyroxine