Use of the New Zealand white rabbit in teratology: incidence of spontaneous and drug-induced malformations.
Cumulative data are presented on the occurrence of external, skeletal and visceral abnormalities in foetuses from teratology studies conducted in New Zealand White rabbits over a 10-yr period. The data, based on examinations of over 5500 control foetuses and 19,000 foetuses from treated dams, are derived from studies involving 58 compounds, five of which were judged to be teratogenic.
D000014:Abnormalities, Drug-Induced / Q000662:veterinary*; D000818:Animals; D001842:Bone and Bones / Q000002:abnormalities / Q000187:drug effects; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000662:veterinary*; D005260:Female; D005298:Fertility / Q000187:drug effects; D005333:Fetus / Q000187:drug effects; D011247:Pregnancy; D011817:Rabbits / Q000196:embryology*; D013723:Teratogens / Q000633:toxicity*
D013723:Teratogens