title: [Myxofibrosarcoma].
abstract: The myxofibrosarcoma is presented as a special entity of soft tissue tumors and differentiated from the myxoid variant of malignant fibrous histiocytoma to which it was often related in the past. Four own cases are described showing the important aspects of this neoplasm. The myxofibrosarcoma can be characterised as a nodular, myxoid tumor which arises in the subcutaneous tissue of the extremities of elderly people (age-range: 68-72 years) and commonly has a favourable prognosis. The histological appearance is dominated by fibroblast-like cells which are usually embedded in a mucoid matrix or less often form highly cellular, sharply delineated areas. A coarse plexiform capillary pattern and an onion-like arrangement of cells around small arteries contribute to the typical histological picture and are helpful diagnostic features. The difficulties of differential diagnosis between the myxofibrosarcoma and other soft tissue tumors are discussed in detail.
mesh_terms: D000367:Age Factors; D000368:Aged; D003937:Diagnosis, Differential; D005121:Extremities; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008297:Male; D011379:Prognosis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*
vernacular_title: Das Myxofibrosarkom.