Laboratory model for infectious bovine keratoconjunctivitis: the pathogenicity of different strains of Moraxella bovis, pathology and ultrastructural observations.
Further studies were made using C57 mice pretreated with a corticosteroid and inoculated with Moraxella bovis by instillation, as a model for infectious bovine keratoconjunctivitis. Strains of M bovis which had previously been tested in cattle produced a generally similar range of pathogenicity when tested in mice. The pathology in the mouse model closely resembled that in cattle and the value of the model for studies on M bovis was confirmed.
D000818:Animals; D001424:Bacterial Infections / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003315:Cornea / Q000648:ultrastructure; D004195:Disease Models, Animal; D005260:Female; D007637:Keratoconjunctivitis / Q000473:pathology / Q000662:veterinary*; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D009016:Moraxella / Q000472:pathogenicity / Q000648:ultrastructure