title: [Syndrome of disseminated intravascular coagulation as the principal morphologic manifestation of shock].
abstract: Examinations of 43 section observations of shock established that the role of the syndrome of disseminated intravascular blood coagulation (DIBC) in the development of shock was variable: in some cases it caused the shock condition (embolism with amniotic waters, premature desquamation of the placenta), in others it is its consequence (hemorrhagic, cardiogenic shock). Morphogenesis of the DIBC syndrome is different depending on its role in the development of the shock condition. The DIBC syndrome as the cause of shock is characterized by completeness of thrombus formation processes and the presence of thrombi consisting of fibrin and/or formed blood elements. The time of formation of microthrombi in various organs is approximately the same and coincides with the period of shock development in the clinical picture. The characteristic morphological features of DIBC as the consequence of the shock include incomplete thrombus formation processes with the presence of pre-thrombi and/or strands and filaments of fibrin, involvement of the adrenals, the presence of the phenomenon of fibrin lining of vascular walls. The time of development of intravascular coagulation does not coincide with shock occurrence and may be different in various parts of the microcirculatory bed.
mesh_terms: D000037:Abruptio Placentae / Q000150:complications; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000473:pathology; D004619:Embolism, Amniotic Fluid / Q000150:complications; D005260:Female; D006801:Humans; D008589:Meningococcal Infections / Q000150:complications; D007744:Obstetric Labor Complications / Q000473:pathology; D011247:Pregnancy; D012769:Shock / Q000150:complications* / Q000209:etiology; D012770:Shock, Cardiogenic / Q000150:complications; D012771:Shock, Hemorrhagic / Q000150:complications
vernacular_title: Sindrom disseminirovannogo vnutrisosudistogo svertyvanie krovi kak osnovnoe morfologicheskoe proiavlenie shoka.