Pressure effects on the apparent viscosity of artificial dipalmitoylphosphatidylcholine and dimyristoylphosphatidylcholine membranes using intramolecular excimer probe.
Emission spectroscopy of intramolecular excimer probes allows the determination of 'equivalent viscosity' of membranes. While increasing the pressure on artificial membrane suspensions, variations in viscosity - essentially related to an increase in the order parameter in the membranes - are observed. In the case of mixed phospholipids, the effect of pressure is amplified, probably due to the existence of holes on the molecular scale between the two lipidic layers.
D004134:Dimyristoylphosphatidylcholine; D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D008954:Models, Biological; D008968:Molecular Conformation; D010713:Phosphatidylcholines; D011312:Pressure; D011663:Pulmonary Surfactants; D011721:Pyrenes; D013050:Spectrometry, Fluorescence; D014783:Viscosity
D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D011721:Pyrenes; C035116:1,3-di-(1-pyrenyl)propane; D004134:Dimyristoylphosphatidylcholine