title: Effect of voluntary running exercise on hypertriacylglycerolemic effect of sucrose in relation to its feeding timing in rats.
abstract: The effect of voluntary wheel-running to modulate sucrose-induced hypertriacylglycerolemia was investigated on both sedentary and exercised rats in relation to the timing of sucrose feeding. The exercised group was allowed voluntary wheel-running between 21.00-08.00. Rats of both groups were daily meal-fed a 35% sucrose diet at 20.00-21.00 and a basal diet at 08.00-09.00, or inversely meal fed the two diets at the reversed time for 7 weeks each. At the end of the feeding period, plasma or serum triacylglycerol (TG) levels of exercised rats, as compared to sedentary rats, showed smaller diurnal changes regardless of the timing of sucrose feeding. Hepatic-intestinal TG secretion rates measured during both resting and physically active periods were lower in the exercised rats than in the sedentary control rats, whereas the cardiac and adipose tissue lipoprotein lipase activity of the two groups was not significantly different. These results suggest that voluntary wheel-running exercise may modulate the hypertriacylglycerolemic effect of sucrose in rats regardless of the timing of sucrose feeding, with decreased TG secretion.
mesh_terms: D000273:Adipose Tissue / Q000201:enzymology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D004435:Eating; D004822:Epididymis / Q000201:enzymology; D005230:Fatty Acids, Nonesterified / Q000097:blood; D050356:Lipid Metabolism; D008071:Lipoprotein Lipase / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000201:enzymology; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D013395:Sucrose / Q000494:pharmacology*; D013997:Time Factors; D014280:Triglycerides / Q000097:blood* / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides; D013395:Sucrose; D002784:Cholesterol; D008071:Lipoprotein Lipase