Effect of experimental Pseudomonas aeruginosa infection on the activity of mouse phagocytes.
It has been stated that experimental infection with 0.01 LD50 Pseudomonas aeruginosa 74 decreases the phagocytic activity of mouse neutrophiles and peritoneal macrophages in relation to latex particles. In the course of infection suppression of phagocytic activity of peritoneal macrophages was delayed for two days as compared with that of neutrophiles. During the dying out of infection phagocytic activity of neutrophils and macrophages returned to the control values. Possible mechanisms of these events were discussed.
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology; D007700:Kinetics; D007928:Lethal Dose 50; D008264:Macrophages / Q000276:immunology* / Q000382:microbiology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008863:Microspheres; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology; D010587:Phagocytosis; D011552:Pseudomonas Infections / Q000276:immunology* / Q000382:microbiology