title: Epibulbar subconjunctival fibroma. A tumor possibly arising from Tenon's capsule.
abstract: A fibroma, a benign neoplasm arising from the periorbita or tendon sheaths, is described in a 74-year-old woman as an indolent, lobular tumor situated in the episcleral and subconjunctival connective tissues with superior limbal fixation. Because most fibromas arise from tendon sheaths or fascial planes, we speculate that our lesion arose from Tenon's capsule. The rarity of periocular fibroma is documented by a review of the modern ophthalmic literature. Histopathologically, the tumor was composed of a paucicellular population of fibroblasts, sometimes displaying hyperchromatic nuclei and widely separated by abundant broad bundles of collagen. Mast cells were infrequently dispersed in the lesion. A wide local excision was performed, and no recurrence has developed during an 18-month follow-up period.
mesh_terms: D000368:Aged; D003228:Conjunctiva / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000473:pathology*; D003238:Connective Tissue / Q000473:pathology; D005142:Eyelid Neoplasms / Q000473:pathology*; D005143:Eyelids / Q000473:pathology; D005260:Female; D005347:Fibroblasts / Q000648:ultrastructure; D005350:Fibroma / Q000473:pathology*; D006801:Humans; D009915:Orbit / Q000473:pathology; D009918:Orbital Neoplasms / Q000473:pathology*