The pathology of Q fever as seen on liver biopsy.
Granulomatous inflammation was seen in liver biopsy specimens from five patients with Q fever. All patients had a fever of unknown origin with mild abnormalities of liver function. The granulomatous process in the liver was very distinctive, with fibrinoid ring formation seen in four of the five cases. A diagnosis of Q fever was suggested in the five cases on the basis of the characteristic granulomatous inflammation. Results of subsequent complement fixation tests were positive in all five patients.
D000328:Adult; D001706:Biopsy; D005260:Female; D006099:Granuloma / Q000473:pathology*; D006519:Hepatitis, Alcoholic / Q000150:complications / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011778:Q Fever / Q000150:complications / Q000473:pathology*