[Blood gas and acid-base changes and rhythmologic tolerance of acetate and bicarbonate hemodialysis using a standard dialyser with high sodium and control of ultrafiltration].
In order to demonstrate a possible superiority of bicarbonate dialysis (HDB) over acetate dialysis (HDA) in conditions of standard dialysis (4 hours on a 1 m2 cuprophan dialyser) but with a bath rich in sodium (143 mEq/l) and control of ultrafiltration, we have compared 2 sequences of 3 runs of HDA and HDB with these conditions in 8 patients as regards their acido-basic and cardiologic parameters (continuous monitoring of ECG by Holter, regular measurement of blood pressure). Acid base balance study in AHD led to the distinction of 2 groups according to wether their plasma bicarbonate increased or decreased during the run. Rythmological tolerance was the same in BHD and AHD, wether all patients or both groups were considered. Heart rate was however slightly but significantly higher during AHD than during BHD, in the patients whose plasma bicarbonate decreased. In conclusion, the benefit of HDB is not remarkable when HDA is performed not only in standard conditions but also with a bath rich in sodium and with control of ultrafiltration.
D000085:Acetates / Q000494:pharmacology*; D000136:Acid-Base Equilibrium; D000328:Adult; D001639:Bicarbonates / Q000494:pharmacology*; D001784:Blood Gas Analysis; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012964:Sodium / Q000494:pharmacology*; D014462:Ultrafiltration
D000085:Acetates; D001639:Bicarbonates; D012964:Sodium
Modifications gazométriques et acido-basiques et tolérance rythmologique durant les hémodialyses acétate et bicarbonate sur dialyseur standard avec sodium élevé et maîtrise de l'ultrafiltration.