Type C virus particles in X63-Ag8.653 mouse plasmacytoma cells and in hybridomas derived from it.
In addition to type A virus particles which are common in Balb/c derived mineral oil induced plasmacytomas, type C virus particles have been found in the plasmacytoma cell lines X63-Ag8 and X63-Ag8.653 used in the hybridoma technique. In hybridomas obtained after fusion of X63-Ag8.653 cells with Balb/c spleen cells, C particles were expressed in 5 out of 13 different clones examined, whereas A particles were always present. Virus expression and antibody production do not exclude each other.
D000818:Animals; D002460:Cell Line; D006825:Hybridomas / Q000382:microbiology* / Q000648:ultrastructure; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D010954:Plasmacytoma / Q000382:microbiology* / Q000648:ultrastructure