[Fetal lung maturity and skin maturity: 2 distinct concepts and the clinical significance of their differences].
The maturation of the fetal lungs, that is to say the adequate production of surfactant in the fetal alveoli, as it is well known reaches to its end about the 35.-36th week of gestation. Even more closely to the date of delivery, about the 37.-38th week of gestation, the maturation of the fetal skin takes place, so to say the detachment of the Vernix caseosa from the fetal skin into the amniotic fluid. The above mentioned means that the children with "mature skin" should have mature lungs too, so that those children have about nothing to fear from the RDS. That can be proved by the comparison of the values which were measured in 38 cases of the L/S Ratio (as a criterion of the lung-maturity), to those of the turbidity of the amniotic fluid and average quantities of the keratinocytes of the amniotic fluid cell population (as a criterion of the skin-maturity); that observation becomes stronger with the comparison of all those values to a Vernix-Score, which can be completed after delivery.
D000653:Amniotic Fluid / Q000032:analysis; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology*; D010713:Phosphatidylcholines / Q000032:analysis; D011663:Pulmonary Surfactants / Q000096:biosynthesis; D012867:Skin / Q000196:embryology*; D013109:Sphingomyelins / Q000032:analysis; D014708:Vernix Caseosa / Q000032:analysis
D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D013109:Sphingomyelins
Lungenreife und Hautreife des Feten: zwei unterschiedliche Begriffe und die klinische Bedeutung ihrer Differenzierung.