Cisplatin-induced bradycardia.
A patient who had repeated episodes of bradycardia while on cisplatin therapy is described. Cisplatin-induced bradycardia has not been reported previously. Deposition of cisplatin in the sinoatrial-node area might explain this cardiotoxic effect.
D001919:Bradycardia / Q000139:chemically induced*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D002945:Cisplatin / Q000009:adverse effects*; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008875:Middle Aged; D010157:Palatal Neoplasms / Q000188:drug therapy; D010160:Palate, Soft; D011674:Pulse / Q000187:drug effects
D002945:Cisplatin