title: An economic and efficacy comparison between morantel (when administered from an intraruminal bolus) and conventional anthelmintic treatment in grazing cattle.
abstract: A economic and efficacy comparison in the control of parasitism in grazing cattle was conducted between conventional anthelmintic treatment applied according to various recommended regimes and an anthelmintic treatment delivered intraruminally at a sustained level from a specially designed bolus. The bolus used was the morantel sustained release bolus which has been designed to prevent the establishment of parasite infections so that, when administered at turnout to all cattle intended to graze the same pasture, parasitologically "safe" pastures could be produced and maintained for an entire grazing season. The various conventional anthelmintic treatment regimes used for the study were selected from the most commonly recommended and used systems of treatment found in commercial use throughout Europe. A total of 471 first-season grazing calves received the morantel sustained release bolus at spring turnout in 38 field trials conducted in Austria, Belgium, Denmark, France, West Germany, Ireland, the Netherlands, Norway, Sweden and the United Kingdom. In each trial, equal numbers of control and bolus-treated animals were maintained on separate halves of a divided pasture. In 25 of the 38 field trials, the control animals received tactical therapy with conventional anthelmintic only when exhibiting signs of parasitic gastroenteritis, while in the remaining 13 trials all animals in each control group received strategic anthelmintic treatment at specified intervals during the grazing season. Compared with control animals, significant reductions in faecal worm egg output of bolus-treated animals was recorded. Subsequent reductions in herbage larval contamination developed on pastures grazed by bolus-treated animals compared with control pastures so that, overall, the bolus-treated animals out-performed the control animals in all 38 trials by a mean of 16.3 kg (P less than 0.05). Labour and management costs (for animal treatment and handling) were substantially reduced in bolus-treated animals compared with animals receiving either tactical or strategic anthelmintic treatment.
mesh_terms: D000818:Animals; D001835:Body Weight; D002417:Cattle / Q000502:physiology; D002418:Cattle Diseases / Q000517:prevention & control*; D003365:Costs and Cost Analysis; D003692:Delayed-Action Preparations; D005060:Europe; D005260:Female; D005759:Gastroenteritis / Q000517:prevention & control / Q000662:veterinary*; D007411:Intestinal Diseases, Parasitic / Q000517:prevention & control / Q000662:veterinary*; D008297:Male; D009015:Morantel / Q000008:administration & dosage* / Q000627:therapeutic use; D010270:Parasite Egg Count / Q000662:veterinary; D010944:Plants / Q000469:parasitology; D011743:Pyrimidines / Q000008:administration & dosage*; D012417:Rumen; D012621:Seasons
chemical_list: D003692:Delayed-Action Preparations; D011743:Pyrimidines; D009015:Morantel