[Measurement of bee venom specific IgG antibody in bee venom hypersensitivity and the relation between the specific IgE antibody and total IgE].
Bee venom specific IgG antibodies for honeybee and common wasp were measured in normal control group, slightly bee injury group, heavy bee injury group and honeybee keeper's group. Relation among bee venom specific IgG antibody, bee venom specific IgE antibody and total IgE was analyzed. Normal control level of bee venom specific IgG antibody was measured under 60 U/ml. Bee venom specific IgG antibody in slightly bee injury group was higher than that in heavy bee injury group. Bee venom specific IgE antibody in slightly bee injury group was lower than that in heavy bee injury group. Bee venom specific IgE antibody in bee keeper's group was very high but bee venom specific IgG antibody was also high. From this results it seems that bee venom hypersensitivity can be prevented by high titer of bee venom specific IgG antibody even if bee venom specific IgE antibody is high titer.
D000328:Adult; D000368:Aged; D000918:Antibody Specificity; D001514:Bee Venoms / Q000276:immunology*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011852:Radioallergosorbent Test / Q000379:methods
D001514:Bee Venoms; D007074:Immunoglobulin G; D007073:Immunoglobulin E