The effect of magnetic fields on platelets, blood coagulation and fibrinolysis in guinea pigs.
Exposure of guinea pigs to homogeneous magnetic fields as low as 0.005 T for 1 hour, 7 days a week, for 6 weeks led to a decreased platelet count; increased platelet aggregation; increased prothrombin and partial thromboplastin times; decreased fibrinogen and increased fibrinolysis. These effects were reversible within 2 months of discontinuation of exposure to the magnetic field. These results suggest an extensive hemorrhagic diathesis combined with a tendency toward thrombosis. Possible mechanisms are discussed.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D001777:Blood Coagulation; D001792:Blood Platelets / Q000502:physiology*; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D005342:Fibrinolysis; D006168:Guinea Pigs; D008297:Male; D010314:Partial Thromboplastin Time; D010974:Platelet Aggregation; D011517:Prothrombin Time; D013997:Time Factors
D000244:Adenosine Diphosphate