title: [Trial control by metrifonate chemotherapy of Schistosoma haematobium in a dry savannah zone in Upper Volta].
abstract: Metrifonate (Bilharcil) was administered in a dose of 7,5 mg/kg, four times at 3 weeks interval to all villagers, regardless of the result of parasite examination, in order to test this treatment of urinary schistosomiasis in a hyperendemic village. On the year following the treatment, three parasite surveys were carried out. They showed a decline in the prevalence and a decrease in number of eggs excreted in the urine. The decrease rate was 91% to 94% in the 10-14 years group, the group with the highest infectivity.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010270:Parasite Egg Count; D012552:Schistosomiasis / Q000188:drug therapy / Q000517:prevention & control*; D014236:Trichlorfon / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000517:prevention & control*
chemical_list: D014236:Trichlorfon
vernacular_title: Essai de lutte par chimiothérapie au métrifonate contre "Schistosoma haematobium" en zone de savane sèche de Haute-Volta.