[Cardiovascular changes among deceased patients with diabetes mellitus and diabetic nephropathy among 9015 autopsied over the age of 14].
Out of 9015 necropsies of patients, over the age of 14, performed between January 1, 1967 and March 1, 1979 at a general hospital in Sofia, 729 of them (8,07%) proved to have diabetes as well. Renal complications were found in 315 of them (43,2%)--chronic pyelonephritis being most frequent (21,2% of all diabetics) followed by diabetic glomerulosclerosis (DG)--18,5 per cent of the diabetics and in 7,9 per cent--a combination of both complications. The authors studied only the patients with DG. They lived about 5,2 years, on the average, less than the other diabetics and 91,1 per cent of them had arterial hypertension versus 61,3 per cent among the rest of the diabetics. A total of 90 per cent of the hypertonics with DG had left ventricular hypertrophy--I--III stage. Atheromatosis of aorta and coronary arteries were found, in those deceased from hypertonic disease, to be more frequent and more severely manifested, than those decreased from chronic pyelonephritis with hypertension and than those deceased from chronic glomerulonephritis with hypertension in all age groups. Regardless of that, the morbidity rate among the deceased with DG from cardiac complications is a little less than that among the deceased from hypertonic disease and the causes for brain vascular complications among diabetics, in spite of the more frequent and more severe atherogenesis has been three times less rare than among the deceased from hypertonic disease. Very likely, the involvement of the kidneys contributes to those discrepancies.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000473:pathology; D001344:Autopsy; D002319:Cardiovascular System / Q000473:pathology*; D003920:Diabetes Mellitus / Q000473:pathology*; D003928:Diabetic Nephropathies / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000473:pathology
Sŭrdechno-sŭdovi promeni pri pochinali sŭs zakharen diabet i diabetna nefropatiia sred 9015 autopsirani nad 14-godishna vŭzrast.