title: [High-performance exclusion liquid chromatography of protected peptides on soft and semi-solid gels].
abstract: Fractionated soft gels Sephadex LH-20, Sephadex LH-60, Enzakryl K-2 and semirigid gels - Spheron P-40, Spheron P-300 and Spheron P-1000 were tested for separation of protected synthetic fragments of neurotoxin II from the Central Asian cobra (Naja naja oxiana) venom. Applicability of the above gels for size exclusion HPLC of protected peptides in organic media is discussed.
mesh_terms: D000595:Amino Acid Sequence; D002850:Chromatography, Gel / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003039:Cobra Neurotoxin Proteins / Q000032:analysis* / Q000302:isolation & purification; D004546:Elapid Venoms / Q000032:analysis*; D005782:Gels; D010455:Peptides / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D003039:Cobra Neurotoxin Proteins; D004546:Elapid Venoms; D005782:Gels; D010455:Peptides
vernacular_title: Vysokoéffektivnaia ékskliuzionnaia zhidkostnaia khromatografiia zashchishchennykh peptidov na miagkikh i poluzhestkikh geliakh.