title: [Pain relief with morphine, intrathecally or peridurally?].
abstract: We investigated pain relief following 1-2 mg morphine intrathecally applied in 7 patients with cancer pains and in 5 patients with multiple rib fractures (group 1). For postoperative pain relief (group 2) we applied 1-2 mg morphine intrathecally in 26 patients immediately before the induction of the anaesthesia. In 30 patients we applied 4 mg morphine epidurally in 10-20 ml saline solution for postoperative pain relief (group 3). In the first group the duration of the pain relief was 25,2 hours, in the second group 31 hours and in the third group 15,7 hours. In the second group a respiratory depression occurred in 3 cases and was successfully treated with naloxon. In the third group a bladder disorder occurred in two cases. Because of the risk of respiratory depression following intrathecally applied morphine, we recommend the epidural way of application.
mesh_terms: D000698:Analgesia / Q000379:methods*; D000767:Anesthesia, Epidural; D006801:Humans; D007278:Injections, Spinal; D009020:Morphine / Q000008:administration & dosage*; D009369:Neoplasms / Q000150:complications; D010146:Pain / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy; D012253:Rib Fractures / Q000150:complications
chemical_list: D009020:Morphine
vernacular_title: Schmerzbekämpfung mit Morphin, intrathekal oder peridural?