[Fenestration of the pulmonary septa as a sign of early destruction in emphysema].
Fenestrations of alveolar septa were found in 8 patients from a group of 9 in samples of macroscopically normal tissue from resected lobes or the whole lungs. Number and diameter of fenestrations related to the length of septa were in correlation with the severity of obstruction examined before operation. Most fenestrations were empty, less often were filled by pneumocytes 2, once by pneumocyte 1. Small fenestrations occurred in intercapillary parts of septa. Junctional complexes between pneumocyte 1 processes were found in margins of fenestrae. When destruction exceeded intercapillary parts of septa capillary circulation was damaged.
D000328:Adult; D000368:Aged; D006801:Humans; D008168:Lung / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000473:pathology*
Fenestrace plicních sept jako projev casné destrukce pri emfyzému.