Complement in allergen-induced bronchospasm in house-dust RAST negative asthmatic patients.
We studied a group of asthmatic patients with aspirin intolerance who were RAST-negative for house-dust and Dermatophagoides-pteronyssinus despite having positive skin tests and positive inhalation tests to these allergens. Total haemolytic activity (CH50), C3, C4 and C3PA were measured after allergen-induced bronchospasm in these patients and also in a group of RAST-positive asthmatic patients taken as a control group. We did not find any change in complement level after allergen-induced bronchospasm in both groups of patients.
D000485:Allergens / Q000276:immunology; D001249:Asthma / Q000209:etiology / Q000276:immunology*; D001985:Bronchial Provocation Tests; D001986:Bronchial Spasm / Q000209:etiology / Q000276:immunology*; D003165:Complement System Proteins / Q000032:analysis*; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D007428:Intradermal Tests; D011852:Radioallergosorbent Test
D000485:Allergens; D004391:Dust; D003165:Complement System Proteins