title: Bone marrow biopsy in the staging of malignant epithelial tumors.
abstract: Bone marrow biopsy was performed routinely on 1,068 patients and 1,268 biopsies were obtained. In 547 epithelial tumors bone marrow involvement was present in 95 patients (17.4%); no metastatic involvement was found in 41 cases of nonepithelial tumors. Bone marrow metastases were present mainly in prostatic (54.1%), breast (26.5%), gastric (18.5%) and lung cancer (7.9%). In 26 cases the primary location was initially unknown; histology was useful in the detection of primary tumors. Histology was compared either with aspiration cytology or with bone X-ray and scan.
mesh_terms: D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology*; D001859:Bone Neoplasms / Q000556:secondary; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002277:Carcinoma / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging / Q000379:methods*; D011859:Radiography; D011877:Radionuclide Imaging