[Use of myocardial scintigraphy with 201Tl for differential diagnosis of ischemic heart disease and hypertrophic cardiomyopathy in women].
Myocardial scintigraphy with 201Tl at rest and under submaximum or threshold stress achieved through bicycle ergometric exercise was used to investigate 31 female patients (14 with coronary disease, 10 with hypertrophic cardiomyopathy, and 7 with cardialgias of varying origins and angiographically unchanged coronary arteries taken as controls). Resting and ergometric-test scintigrams of the controls showed no areas of disordered myocardial perfusion. Thallium distribution in the myocardium was even. All coronary patients showed areas of transitory myocardial ischemia in response to exercise. In all patients with hypertrophic cardiomyopathy, the scintigrams revealed a diminished and hardly visible left-ventricular cavity. Also, their resting scintigrams showed areas of decreased myocardial perfusion, similar to those noted in coronary patients. However, the exercise scintigrams never showed any extension or reduction of thallium uptake defects in patients with hypertrophic cardiomyopathy. Perfusion myocardial scintigraphy with 201Tl can be recommended as an additional method of differential diagnosis between coronary disease and hypertrophic cardiomyopathy in female patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium
D011868:Radioisotopes; D013793:Thallium
Primenenie stsintigrafii miokarda s 201Tl dlia differentsial'noĭ diagnostiki ishemicheskoĭ bolezni serdtsa i gipertroficheskikh kardiomiopatiĭ u zhenshchin.