title: [Comparative studies on the bioavailability of 2 amoxicillin preparations].
abstract: The bioavailability of alpha-amino-4-hydroxybenzyl-penicillin (amoxicillin) was investigated after administration of two different preparations. As test substance Sigamopen tablets were given and compared with a standard-preparation on the German market. Both preparations contained 750 mg amoxicillin. No significant differences were found in the serum concentrations, in the bioavailability or other pharmacokinetic parameters. The results obtained are in agreement with those known in the literature. Therefore, both preparations were regarded as bioequivalent.
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage / Q000378:metabolism*; D001682:Biological Availability; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D013607:Tablets; D013997:Time Factors
chemical_list: D013607:Tablets; D000658:Amoxicillin
vernacular_title: Vergleichende Untersuchungen zur Bioverfügbarkeit zweier Amoxicillin-Präparate.