Amplitude and pulse rate difference limens for electrical stimulation of the cochlea following graded degeneration of the auditory nerve.
Experimentally deafened cats with differing populations of residual spiral ganglion cells were implanted with cochlear electrodes and were electrically stimulated. They were conditioned to respond to changes in electrical pulse rate and amplitude, and both electrical pulse rate and amplitude difference limens were determined. It was found that although there were some variations in difference limens between animals, these showed no correlation with residual cell populations over the range 8-44%.
D000161:Acoustic Stimulation; D000818:Animals; D001309:Auditory Threshold; D001522:Behavior, Animal; D002415:Cats; D003051:Cochlea / Q000502:physiology*; D003054:Cochlear Implants; D003214:Conditioning, Classical; D003638:Deafness / Q000503:physiopathology; D004056:Differential Threshold; D004558:Electric Stimulation; D013136:Spiral Ganglion / Q000166:cytology; D000159:Vestibulocochlear Nerve