A crossover comparative study with two bulk laxatives.
Twenty elderly in-patients suffering from severe constipation were treated once daily for 2 weeks with each of two bulk laxatives. The preparations were allocated randomly as the first and second preparation. Agiolax, the new preparation, contained 15 mg senna glucosides, the old preparation, Lunelax comp., contained 25 mg senna glucoside A + B per dose. Both preparations worked well and no side-effects were seen.
D000368:Aged; D002400:Cathartics / Q000627:therapeutic use*; D003248:Constipation / Q000188:drug therapy*; D004338:Drug Combinations / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D010943:Plantago; D011060:Poloxalene / Q000627:therapeutic use*; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011620:Psyllium / Q000627:therapeutic use*; D012676:Senna Extract / Q000627:therapeutic use*
D002400:Cathartics; D004338:Drug Combinations; D010936:Plant Extracts; C028394:lunelax; D011092:Polyethylene Glycols; C024255:ispaghula, senna drug combination; D012676:Senna Extract; D011620:Psyllium; D011060:Poloxalene