[Analysis of intraluminal flow velocity profile in peripheral arterial reconstruction--with special reference to the effect of abnormal flow wave on postoperative thrombosis formation].
Normal and abnormal flow wave forms electromagnetically determined in the reconstructed peripheral arteries were analysed in terms of luminal velocity profile using a model pump system "Flow Wave Form Simulation Pump" which was designed and constructed by us. In the blood flow with normal flow wave, the velocity gradient in the limited layer adjacent to the wall at the straight as well as dilatated or constricted part of the conduit was found to become larger with formation of a boundary layer. In addition, a respective fluctuation on velocity, including reversal stream during the phase of cardiac diastole, was found to be characteristic in a cardiac cycle. In contrast, in the flow with abnormal wave, the velocity in the layer adjacent to the wall was always stagnant with little alteration in velocity gradient during each phase of a cardiac cycle. A stagnation of flow velocity in the layer adjacent to the wall would be a source in facility of platelet deposition on the luminal surface of the reconstructed artery, and such would lead to vascular occlusion. Accordingly, it was highly considered that the flow wave form is a useful indicator to assess the outcome of the reconstructive surgery since the hemodynamic property of the reconstructed artery is reflected in the electromagnetically determined flow wave form.
D001158:Arteries / Q000503:physiopathology / Q000601:surgery*; D001783:Blood Flow Velocity; D008955:Models, Cardiovascular; D011183:Postoperative Complications; D011379:Prognosis; D013927:Thrombosis / Q000209:etiology*