Pharmacological study of CDP-choline. Protection against toxicity in a model of experimental hypoxia.
The influence of oral cytidine diphosphate choline (CDP-choline, citicoline, Somazina) on the experimental toxicity induced by potassium cyanide is investigated. Animals receiving a preventive treatment with CDP-choline were protected.
D000818:Animals; D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000627:therapeutic use*; D000860:Hypoxia / Q000139:chemically induced / Q000188:drug therapy*; D007980:Levodopa / Q000494:pharmacology; D008297:Male; D051379:Mice; D011190:Potassium Cyanide; D013997:Time Factors
D007980:Levodopa; D003566:Cytidine Diphosphate Choline; D011190:Potassium Cyanide; D002794:Choline