[Various characteristics of erythrocyte membrane proteins in rats with spontaneous hypertension].
Differential scanning microcalorimetry demonstrated an increase in specific heat capacity of erythrocyte membranes of spontaneously-hypertensive rats around 63 degrees C (C-transition). Disc electrophoresis with sodium dodecyl sulphate showed the percentage of band 3 peptides to be increased in relation to all membrane peptides in these membranes. It is suggested that the elevated content of band 3 peptides, which are known to participate in the formation of anion channels in mammalian erythrocyte membranes, may be one of the causes of increased specific heat of C-transition.
D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism*; D001692:Biological Transport; D002463:Cell Membrane Permeability; D004589:Electrophoresis, Disc; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006358:Hot Temperature; D006973:Hypertension / Q000097:blood*; D008565:Membrane Proteins / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D001457:Anion Exchange Protein 1, Erythrocyte; D008565:Membrane Proteins
Nekotorye osobennosti membrannykh belkov éritrotsitov krys so spontannoĭ gipertenzieĭ.