Atracurium in clinical anaesthesia.
Atracurium was used on 250 occasions under normal operating conditions in patients between the ages of 18 and 86 yr; 97 patients were aged 65 yr and over, 47 were ASA Grade III, 15 were Grade IV and three were Grade V. Provided that a dose of 0.5-0.6 mgkg-1 was used, intubation was carried out in 1.5 min in 82% of patients. Good operating conditions were obtained in all patients and no complications could be attributed to atracurium even in patients giving a history of allergy or asthma. Residual blockade could be adequately antagonized and recurarization did not occur.
D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001279:Atracurium; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D007431:Intraoperative Complications; D007442:Intubation, Intratracheal; D007546:Isoquinolines / Q000037:antagonists & inhibitors; D008297:Male; D008875:Middle Aged; D009388:Neostigmine / Q000494:pharmacology; D009466:Neuromuscular Blocking Agents / Q000037:antagonists & inhibitors; D012119:Respiration
D007546:Isoquinolines; D009466:Neuromuscular Blocking Agents; D001279:Atracurium; D009388:Neostigmine