title: Increased long chain acyl CoA in Duchenne muscular dystrophy.
abstract: Compared with normal or denervated human muscle, long chain acyl CoA was increased in muscle from patients with Duchenne dystrophy. Free and short chain acylcarnitine were reduced in Duchenne muscle, whereas long chain acylcarnitine was preserved. The accumulation of long chain fatty acid derivatives may imply disruption of fatty acid oxidation.
mesh_terms: D000214:Acyl Coenzyme A / Q000378:metabolism*; D002331:Carnitine / Q000378:metabolism; D006801:Humans; D009136:Muscular Dystrophies / Q000201:enzymology*
chemical_list: D000214:Acyl Coenzyme A; D002331:Carnitine