title: [Dysplastic changes in the development of bone tissue in congenital pseudarthrosis].
abstract: Angiographic examinations of shin blood vessels were carried out in 11 patients of 2 1/2 to 16 years with congenital false joints, and in 3 of these patients also pathomorphological and ultrastructural studies of the bone and cartilage tissue from the false joint area were performed. The deepest disorders of the blood supply were found at the level of the false joint. Dysplastic changes in the bone consisted in disorders of normal osteogenesis and atypical development of the cartilage, thinning of the bone structures, ultrastructural invalidity of osteocytes and insufficient mineral saturation of the organic matrix. Dystrophy of chondrocytes and deficient ultrastructure of collagen fibrills were noted.
mesh_terms: D000293:Adolescent; D001857:Bone Matrix / Q000648:ultrastructure; D001862:Bone Resorption; D002356:Cartilage / Q000648:ultrastructure; D002648:Child; D002675:Child, Preschool; D003094:Collagen; D006801:Humans; D010011:Osteocytes / Q000648:ultrastructure; D011542:Pseudarthrosis / Q000151:congenital* / Q000473:pathology; D013977:Tibia / Q000002:abnormalities* / Q000098:blood supply / Q000473:pathology
chemical_list: D003094:Collagen
vernacular_title: Displaticheskie narusheniia razvitiia kostnoĭ tkani pri vrozhdennykh lozhnykh sustavakh.