Histidinomycin, a new antifungal antibiotic.
A new antifungal antibiotic named histidinomycin was isolated from the broth filtrate of a streptomycete, tentatively designated as isolate H 878-MY 1. Histidinomycin was purified as the monohydrochloride and the molecular formula was proposed to be C22H30N8O11.HCl. The antibiotic gave histidine by acid hydrolysis. Histidinomycin showed rather narrow antimicrobial spectrum for only few genera of phytophathogenic fungi.
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents / Q000302:isolation & purification*; D023181:Antimicrobial Cationic Peptides; D002473:Cell Wall / Q000032:analysis; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010455:Peptides / Q000302:isolation & purification / Q000633:toxicity; D013053:Spectrophotometry; D013171:Spores, Bacterial / Q000648:ultrastructure; D013302:Streptomyces / Q000254:growth & development
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D023181:Antimicrobial Cationic Peptides; D010455:Peptides; C040321:histidinomycin