title: [Oncological characteristics of CC57BR mice].
abstract: The oncologic and non-oncologic morbidity in intact CC57BR mice was studied over a period of 1978-1980. Tumors occurred in 23.5%, while malignant tumors were in 14.3% of mice. Benign adenomas of lung were the most frequent 10.9%. Malignant tumors included generalized reticulosarcomatosis and leukemia 6.8%, cancer of the skin 3.4% and single different tumors. Pneumonia and enteritis were the most frequent among non-oncologic diseases. Since CC57BR mice belong to a low cancer line, they should be used for various long-term cancer and non-cancer experiments.
mesh_terms: D000236:Adenoma / Q000453:epidemiology; D000367:Age Factors; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D007942:Leukemia, Experimental / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000453:epidemiology*; D012737:Sex Factors; D012878:Skin Neoplasms / Q000453:epidemiology; D014586:USSR
vernacular_title: Onkologicheskaia kharakteristika mysheĭ linii CC57BR.