[Peptide interactions in the intestines of birds].
Interaction among various dipeptides was studied during their uptake in the mucosa of the small intestine of chicks. The effects observed were either inhibiting (L-valyl-L-valine inhibited the uptake of glycyl-L-alpha-alanine, glycyl-L-proline, L-leucyl-glycine, glycylglycine, and L-alpha-alanyl-L-alpha-alanine inhibited the uptake of glycyl-L-proline and L-leucylglycine) or stimulating (L-valyl-L-valine activated the uptake of glycyl-L-leucine), or neutral (L-alpha-alanyl-L-alpha-alanine exerted no significant effect on the absorption of glycyl-L-leucine and glycyl-L-valine). The amount and direction of the modifying effect depended on the agent concentration. Effects observed during the interaction of dipeptides and mixtures of free amino acids equimolar to them were identical. It is only possible if hydrolytic processes precede the transport and are closely related to them.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001692:Biological Transport; D002645:Chickens / Q000378:metabolism*; D004151:Dipeptides / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005215:Fasting; D005609:Free Radicals; D006868:Hydrolysis; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism; D007421:Intestine, Small / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*
D000596:Amino Acids; D004151:Dipeptides; D005609:Free Radicals; D010455:Peptides
Vzaimodeĭstvie peptidov v kishechnike ptits.