Activity of AMP against experimental herpes simplex virus type 1 infections in mice.
Administration of AMP soon after inoculation of mice with herpes simplex virus type 1 inhibited development of virus-induced lesions and appeared to prevent establishment of virus latency. These effects were dependent on both the AMP dose and the time of AMP administration. Regression of herpes simplex virus type 1-induced lesions was also accelerated significantly by AMP treatment in a time- and dose-dependent manner.
D000249:Adenosine Monophosphate / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D006561:Herpes Simplex / Q000188:drug therapy*; D051379:Mice; D013997:Time Factors
D000249:Adenosine Monophosphate