Hormone-releasing stimuli do not alter Met-enkephalin levels in the rat neurohypophysis.
The levels of met-enkephalin in the rat neurohypophysis were measured by radioimmunoassay in four groups of animals. The groups were a control untreated group, a sham operated group, a group subjected to 1% body weight haemorrhage which is an acute hormone releasing stimulus, and a group subjected to four days 2% saline imbibition which is a chronic hormone releasing stimulus. In none of the groups was the met-enkephalin level significantly different from the control value of 1.90 +/- 0.18 ng/gland (n = 10), suggesting that there was no depletion of met-enkephalin concomitant with the depletion of neurohypophysial hormones in the rat.
D000818:Animals; D004744:Enkephalin, Methionine / Q000378:metabolism*; D006470:Hemorrhage / Q000503:physiopathology*; D006728:Hormones / Q000378:metabolism*; D008297:Male; D010904:Pituitary Gland, Posterior / Q000378:metabolism*; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains
D006728:Hormones; D004744:Enkephalin, Methionine