Graft-versus-host disease in lymphoblastic lymphoma following blood transfusions.
The case of a 20-year-old man with lymphoblastic lymphoma in leukemic phase succumbing to acute graft-versus-host disease (GVHD) following intensive chemotherapy and blood transfusions is described. Such a documented association has rarely been reported in the literature. The issue of irradiating blood components prior to transfusion in patients with suspected cell-mediated immunodeficiency receiving intensive chemotherapy is raised and discussed.
D000328:Adult; D006086:Graft vs Host Disease / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology* / Q000628:therapy; D008297:Male; D065227:Transfusion Reaction