[Limited indications for phenotyped blood in the prevention of transfusion-induced anti-red blood cell alloimmunization in chronic kidney failure].
Records from 506 multitransfused patients on a program of hemodialysis were reviewed to evaluate the incidence of transfusion-induced red cell alloimmunization. Out of 405 patients having received a total of 6608 red cell transfusions compatible for A, B and D antigens, only 7 patients (1.72%) developed allo-antibodies which may be attributed to such transfusions. Elaborate red cell phenotyping in non-immunized patients and selection of blood units compatible for other antigens than D does not accordingly appear to be justified and cost-effective.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001788:Blood Grouping and Crossmatching; D002648:Child; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000276:immunology*; D007676:Kidney Failure, Chronic / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D065227:Transfusion Reaction
D007518:Isoantibodies
Limite des indications du sang phénotypé pour la prévention de l'alloimmunisation transfusionnelle anti-globules rouges dans l'insuffisance rénale chronique.