Polymeric structure of a high-molecular-weight glycoprotein from bovine cervical mucus.
A 16 X 10(6)-Mr glycoprotein isolated from bovine oestrus cervical mucus when reduced under conditions where disulphide-bond cleavage is essentially quantitative produces chains whose Mr from light-scattering and from sedimentation and diffusion data is some 4 X 10(6)-5 X 10(6). Pronase digestion of the chains indicates that glycosylated sequences of Mr 0.3 X 10(6)-0.5 X 10(6) are interspersed with enzyme-susceptible non-glycosylated peptide sequences.
D000478:Alkylation; D000818:Animals; D001704:Biopolymers; D002417:Cattle; D002582:Cervix Mucus / Q000032:analysis*; D005260:Female; D006023:Glycoproteins; D008970:Molecular Weight; D010084:Oxidation-Reduction; D010446:Peptide Fragments / Q000032:analysis; D011402:Pronase
D001704:Biopolymers; D006023:Glycoproteins; D010446:Peptide Fragments; D011402:Pronase