Treatment of Torulopsis glabrata peritonitis with intraperitoneal amphotericin B.
Torulopsis glabrata peritonitis occurred in a patient after surgery for a ruptured abdominal viscus. The infection was successfully treated with intraperitoneal amphotericin B alone. Pharmacokinetic information regarding the distribution and clearance of amphotericin B administered by this route is presented, and the clinical manifestations and treatment modalities for T glabrata and Candida peritonitis are reviewed.
D000005:Abdomen / Q000601:surgery; D000666:Amphotericin B / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D001202:Ascitic Fluid / Q000382:microbiology; D002175:Candida / Q000302:isolation & purification; D006801:Humans; D007274:Injections, Intraperitoneal; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy*; D010537:Peritoneum / Q000378:metabolism; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D013530:Surgical Wound Infection / Q000382:microbiology
D000666:Amphotericin B