Possible relationship of Chlamydia to multiple sclerosis.
Multiple sclerosis is an acquired disease of the central nervous system, probably due to a transmissible factor, and characterized by pathological changes in the white matter of the brain and cord. These changes consist of loss of the myelin covering of the axons in the form of demyelinative plaques. Based on a review of the following studies, Chlamydia may indeed be one of the agents involved in the pathophysiology of multiple sclerosis.
D002690:Chlamydia Infections / Q000150:complications*; D006801:Humans; D009103:Multiple Sclerosis / Q000209:etiology* / Q000382:microbiology; D012282:Rickettsia Infections / Q000150:complications*