title: [Long-term results of treatment of 3,359 patients with breast cancer].
abstract: The paper presents the data on 3359 cases of breast cancer treated at the Institute. A slight (4.7-7.6%) though significant increase in five-year survival was registered within 20 years (1955-1975). It had gone up to 64.7% by 1971-1975. A significant increase was observed in patients under 50 years who received an adjuvant postoperative chemotherapy (thiotepa and 5-fluorouracil). Mortality from distant metastases within the first 15 years after the beginning of therapy decreased from 89.5 to 68.8% and it was as low as 7.6% at later periods.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D002369:Castration; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis; D008408:Mastectomy; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D006728:Hormones
vernacular_title: Otdalennye rezul'taty lecheniia 3359 bol'nykh rakom molochnoĭ zhelezy.