[Correlation of psychological and neurological changes with indicators of exposure of workers in a shoe factory to glue solvents].
In the group of 349 women exposed to organic solvents, chiefly extraction naphtha, n-hexane and toluene, medical examinations were carried out. Among them the 100 persons without signs of chronic intoxication were selected. In this group the following examinations were performed: Graham-Kendall's and Bender's psychologic tests, electroencephalograms, testing motor conduction of peripheral nerves. In the exposed and control groups urinary phenol and hippuric acid content was determined. Air solvents concentration at work environment was also measured. Within the examined group, psychologic tests score was as follows: 37 persons without organic changes, 28 on the border-1 and of the norm, 35 with cortical organic changes. No significant difference in average urinary phenol and hippuric acid content was found in 3 groups mentioned above. The hippuric acid excretion in the exposed group was significantly higher than in the control one. Hippuric acid in workers with normal and abnormal electrocardiograms was at the same level. No difference in the hippuric acid concentration in groups with normal and slowed nerve conduction velocity was noticed. The urinary phenol content in the exposed and control groups was at the same level. At some work posts extraction naphtha and toluene concentration exceeded MAC. Cortical organic changes and subclinical neuropathy were significantly more frequent in workers exposed to high concentrations of extraction naphtha and toluene. The authors suppose that subclinical signs, detectable by means of psychologic and neurophysiologic methods, may be considered as early symptoms of individual reaction to organic solvents.
D000269:Adhesives / Q000633:toxicity*; D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D005260:Female; D006626:Hippurates / Q000652:urine; D006801:Humans; D008475:Median Nerve / Q000187:drug effects; D008570:Memory, Short-Term / Q000187:drug effects; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects; D010543:Peroneal Nerve / Q000187:drug effects; D010636:Phenols / Q000652:urine; D012775:Shoes; D012997:Solvents / Q000633:toxicity*; D013979:Tibial Nerve / Q000187:drug effects; D014459:Ulnar Nerve / Q000187:drug effects
D000269:Adhesives; D000395:Air Pollutants, Occupational; D006626:Hippurates; D010636:Phenols; D012997:Solvents; C030514:hippuric acid
Korelacja zmian psychologicznych i neurologicznych ze wskaźnikami narazenia na rozpuszczalniki klejów obuwniczych u pracowników fabryki obuwia.