Detection and analysis of aminoparathion in human postmortem specimens.
Postmortem samples from two fatalities involving parathion ingestion were examined. Parathion could not be detected in the liver tissue but a significant quantity of a related compound was detected. This was shown to be aminoparathion, a biotransformation product of parathion. The substances were extracted with hexane and analyzed by gas-liquid chromatography on a 3% OV-210 column. Thin-layer chromatography and mass spectrometry were also performed. The transformation of parathion to aminoparathion in human tissue has not been previously reported.
D001711:Biotransformation; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005554:Forensic Medicine; D006801:Humans; D013058:Mass Spectrometry; D010278:Parathion / Q000031:analogs & derivatives* / Q000378:metabolism / Q000506:poisoning*; D014018:Tissue Distribution
C016224:aminoparathion; D010278:Parathion