Studies on the hydrolysis of biocompatible acrylic polymers having aspirin-moieties.
Both the homogeneous and heterogeneous hydrolysis of five new acrylic polymers having aspirin-moieties, i.e. polymers of beta-(acetylsalicylyloxy)ethyl methacrylate, beta-(acetylsalicylyloxy) propyl methacrylate,beta-(acetylsalicylyloxy) ethyl acrylate, beta-hydroxy-gamma-(acetylsalicylyloxy) propyl methacrylate, beta-hydroxy-gamma-(acetylsalicylyloxy) propyl acrylate were investigated in acidic or alkaline medium at 30 degrees C or 60 degrees C, respectively. It was observed that the chief hydrolyzed product is always aspirin with minor amount of salicylic acid.
D000179:Acrylates; D001241:Aspirin; D001672:Biocompatible Materials; D006868:Hydrolysis; D008689:Methacrylates; D011109:Polymethacrylic Acids; D013056:Spectrophotometry, Ultraviolet
D000179:Acrylates; D001672:Biocompatible Materials; D008689:Methacrylates; D011109:Polymethacrylic Acids; D001241:Aspirin