Androgen influences on glucosamine 6-phosphate synthase in the epididymis of the rat.
Glucosamine 6-phosphate synthase activity in the total, caput, and cauda epididymis was estimated. Efferent duct ligation for 7 or 16 days caused significant reduction in the enzyme activity of caput epididymidis only and had no effect on the cauda epididymidis. Treatment with dihydrotestosterone (DHT) at a dose of 100 micrograms per day restored the enzyme activity in the caput epididymidis.
D000818:Animals; D002238:Carbohydrate Epimerases / Q000378:metabolism*; D013196:Dihydrotestosterone / Q000494:pharmacology*; D004822:Epididymis / Q000187:drug effects / Q000201:enzymology*; D005945:Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D013196:Dihydrotestosterone; D005945:Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); D002238:Carbohydrate Epimerases