Incidence of hepatitis A virus infection among Japanese volunteers staying in developing countries.
Incidence of hepatitis A virus infection was studied serologically in 260 adult males and females sent for volunteer service to developing countries from Japan. Among 225 initially seronegative subjects, 29 (12.9%) were seropositive to hepatitis A virus at their return from two year's overseas service. Seroconversion occurred in none of 39 subjects who received two doses or more of prophylactic administration of human immunoglobulin. There were clinical records of acute non-B hepatitis in 10 subjects among 29 who seroconverted to hepatitis A virus, while in 6 among 231 who did not seroconvert.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D003906:Developing Countries; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology*; D035922:Hepatitis A Antibodies; D006801:Humans; D007564:Japan / Q000208:ethnology; D008297:Male; D014838:Volunteers
D000914:Antibodies, Viral; D035922:Hepatitis A Antibodies