Ventricular fibrillation following AMSA. Uncomplicated retreatment following correction of hypokalemia.
A patient is presented who developed ventricular fibrillation following AMSA treatment, in the setting of hypokalemia. Resuscitation was successful, chemotherapy treatment response was observed, and further treatment with AMSA was uncomplicated after correction of the hypokalemia. With careful attention to electrolyte balance, a prior history of AMSA-induced cardiac arrhythmia does not contraindicate further treatment with AMSA.
D000328:Adult; D000609:Aminoacridines / Q000009:adverse effects*; D000677:Amsacrine; D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000150:complications*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D014693:Ventricular Fibrillation / Q000139:chemically induced*
D000609:Aminoacridines; D000970:Antineoplastic Agents; D000677:Amsacrine