[Effect of proteolytic enzyme inhibitors on lung cell population function in normal mice and in the development of tourniquet shock].
Cell populations of mice lungs have been studied for variations in the lavage and lumen of the alveoli. The development of the tourniquet shock induces a decrease in the number of macrophages and lymphocyte and an increase in the number of neutrophils, erythrocytes and epithelium cells. Application of the proteolysis enzyme inhibitors is found to stabilize the bronchoalveolar barrier and to prevent these changes.
D000818:Animals; D002452:Cell Count; D004353:Drug Evaluation, Preclinical; D008168:Lung / Q000166:cytology / Q000187:drug effects*; D008297:Male; D051379:Mice; D011480:Protease Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D011650:Pulmonary Alveoli / Q000166:cytology / Q000187:drug effects; D012769:Shock / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors; D014111:Tourniquets
D011480:Protease Inhibitors
Vliianie ingibitorov proteoliticheskikh fermentov na sostoianie kletochnykh populiatsiĭ legkogo myshi v norme i pri razvitii turniketnogo shoka.