The fragile X: a scanning electron microscope study.
Scanning electron microscopy (SEM) has been used to study the fragile X chromosome. The fragile site appears as an isochromatid gap in the majority of cases, confirming light microscope (LM) observations. SEM has allowed a more precise location of the fragile site to the Xq27 . 3 region.
D002874:Chromosome Mapping; D005260:Female; D005600:Fragile X Syndrome / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008855:Microscopy, Electron, Scanning; D012729:Sex Chromosome Aberrations / Q000473:pathology*; D014960:X Chromosome / Q000648:ultrastructure*