[Inhibition of motility and cytoprotective action of supidimide in the human stomach].
200 mg of Supidimide inhibit the spontaneous motility of the stomach for 90 to 120 min after oral administration. The effect is significant (placebo-control). 100, 200, and 400 mg of Supidimide decrease significantly the gastric transmural potential difference curves triggered with ethanol.
D000431:Ethanol / Q000494:pharmacology; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D008875:Middle Aged; D013270:Stomach / Q000187:drug effects* / Q000502:physiology; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000494:pharmacology
D000431:Ethanol; D013792:Thalidomide; C027948:supidimide
Untersuchung der motilitätshemmenden und cytoprotektiven Wirkung von Supidimid auf den menschlichen Magen.