title: [Urethral pressure profile in anesthetized and decerebrated dogs].
abstract: The urethral pressure profile (UPP) was studied and compared in anesthetized and decerebrated dogs. The maximum urethral closure pressure (UPmax) was measured in various procedures. In anesthetized dogs UPmax was 70.9 +/- 22.9 cmH2O (mean +/- S.D.) in control, 40.2 +/- 16.4 cmH2O in laparotomy and 26.5 +/- 12.5 cmH2O in resection of pubic bone. As procedures were added, UPmax decreased, and the shape of UPP in anesthetized dogs showed remarkable change. In decerebrated dogs UPmax was 96.9 +/- 14.9 cmH2O in control, 77.5 +/- 28.0 cmH2O in decerebration, 78.1 +/- 7.0 cmH2O in 3 hours after decerebration, 79.0 +/- 6.8 cmH2O in laparotomy and 49.6 +/- 7.0 cmH2O in resection of pubic bone. UPP in decerebrated dogs generally kept its shape in various procedures and UPmax showed no change before and after laparotomy. Therefore, decerebrated dogs were considered to be useful for the experimental model of UPP.
mesh_terms: D000758:Anesthesia; D000818:Animals; D003655:Decerebrate State / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D008297:Male; D011312:Pressure; D014521:Urethra / Q000503:physiopathology*; D014563:Urodynamics