[Immunosuppressive acidic glycoprotein (IAP) and immunosuppressive substance].
Serum IAP and IS levels were studied in patients with stomach cancer. We found that the serum levels of IAP and IS increased as the disease progressed; their true positive rates as tumor markers were 49.3% and 39.8%, respectively. There was some delicate difference between these glycoproteins and T-cell subpopulation. IAP and IS correlated well with a correlation coefficient of 0.847, their value in clinical oncology are thought to be equivalent. Some difference was found between their substances and ASP, this might indicate the heterogeneous nature of the circulating glycoproteins in varying cancer-bearing status.
D000230:Adenocarcinoma / Q000097:blood / Q000276:immunology / Q000473:pathology; D002918:Chymotrypsin / Q000037:antagonists & inhibitors / Q000097:blood; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007111:Immunity, Cellular; D009363:Neoplasm Proteins / Q000097:blood*; D012794:Sialic Acids / Q000097:blood; D013274:Stomach Neoplasms / Q000097:blood* / Q000276:immunology / Q000473:pathology; D000514:alpha 1-Antichymotrypsin
D006023:Glycoproteins; D009363:Neoplasm Proteins; D012794:Sialic Acids; D000514:alpha 1-Antichymotrypsin; C030193:immunosuppressive acidic protein; D002918:Chymotrypsin