Some new data on the mechanism of the oxygen metabolism kinetics error in glaucoma.
The paper presents the results of the study on oxygen metabolism in glaucoma patients. In the study a combined method, including oxyhemography and polarography, was used: a) for the determination of the tissue oxygen absorbtion constant (TOAC); and b) for the determination of the blood oxygen discharge rate (BODR) performed by the method of polarographic coulonometry. In 93 glaucoma patients, various forms, stages, and intraocular pressure compensation degree were examined. The results of the oxyhemographic measurements showed oxygen deficiency in the majority of patients. In 41 patients, TOAC determination showed the increase of these values by 38%. The blood oxygen discharge rate (BODR) also exceeded the norm. The above-mentioned results indicate some significant errors of the oxygen metabolism at all stages of glaucoma.
D000368:Aged; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000378:metabolism*; D006801:Humans; D000860:Hypoxia / Q000150:complications; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D010101:Oxygen Consumption; D012867:Skin / Q000378:metabolism
D010100:Oxygen