Determination of N-mononitrosopiperazine and N,N'-dinitrosopiperazine in human urine, gastric juice and blood.
A rapid, selective and sensitive method for the determination of N-mononitrosopiperazine and N,N'-dinitrosopiperazine in human urine, gastric juice and blood has been developed using gas-liquid chromatography with thermal energy analysis. The compounds were isolated by extraction and Extrelut with dichloromethane or chloroform. The detection limits were between 0.2 and 2 ng/ml.
D002849:Chromatography, Gas / Q000379:methods; D005750:Gastric Juice / Q000032:analysis*; D006801:Humans; D009602:Nitrosamines / Q000032:analysis* / Q000097:blood / Q000652:urine; D013997:Time Factors
D009602:Nitrosamines; C026156:N,N'-dinitrosopiperazine; C014711:1-nitrosopiperazine