Effect of nonsteroidal anti-inflammatory drugs on the renal excretion of uric acid.
The effect of 9 nonsteroidal anti-inflammatory drugs on the renal excretion of uric acid was studied in patients with normal renal function. Diflunisal, Azapropazone and Indomethacin caused an increase and Piroxicam a decrease in the uric acid excretion. Other drugs studied had no significant influence.
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001168:Arthritis / Q000150:complications / Q000628:therapy / Q000652:urine*; D006073:Gout / Q000150:complications / Q000188:drug therapy / Q000652:urine*; D006801:Humans; D010894:Piroxicam; D011799:Quinazolines / Q000627:therapeutic use; D013843:Thiazines / Q000627:therapeutic use; D014527:Uric Acid / Q000652:urine*; D062367:ortho-Aminobenzoates / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D011799:Quinazolines; D013843:Thiazines; D062367:ortho-Aminobenzoates; D010894:Piroxicam; D014527:Uric Acid; C009500:tolfenamic acid; C011385:proquazone