Prevalence of diabetic microangiopathy and neuropathy among Japanese diabetics in the Tokyo area: related to the WHO new diagnostic criteria.
In accordance with the new criteria for diabetes mellitus proposed by the WHO in 1980, patients treated at our clinic from 1976 to 1980 were examined for diabetes mellitus and its three major complications. 3809 patients (M 2176, F 1630) were divided into three groups: DM-A group (2912) with fasting plasma glucose (FPG) greater than or equal to 140 mg/100 ml; DM-B group (334) with FPG less than 140 and 2 hr after load (2H) greater than or equal to 200; IGT group (563) with FPG less than 140 and 140 less than or equal to 2H less than 200. The prevalences of the three complications are presented in the order: DM-A; DM-B; IGT, 33%; 21%; 15% (proteinuria), 48%; 28%; 18% (retinopathy), 63%; 47%; 34% (neuropathy), 15%; 6%; 1% (triopathy). Among the diabetics groups (DM-A + DM-B), prevalence of retinopathy is examined by sex, known duration of diabetes and age at registration. Prevalence is 45% in male, and 47% in female; duration 0-2 yr 27%, 3-5 yr 37%, 6-8 yr 50%, 9-11 yr 59%, 12-14 yr 68%, 15 yr- 73%; age at registration 0-24 yr 23%, 25-44 yr 39%, 45-64 yr 50%, 65 yr- 47%. On crosstabulation of age and duration in 25-44 yr age group, the prevalence of retinopathy as a function of known duration is 22% (duration 0-2 yr), 29% (3-5 yr), 53% (6-8 yr), 62% (9-11 yr), 73% (12-14 yr), 90% (15 yr-) and the prevalence rises more steeply than elder ones.(ABSTRACT TRUNCATED AT 250 WORDS)
D000328:Adult; D000368:Aged; D003925:Diabetic Angiopathies / Q000175:diagnosis / Q000453:epidemiology*; D003929:Diabetic Neuropathies / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis / Q000453:epidemiology; D014041:Tokyo; D014944:World Health Organization