Interrupted pregnancy as an indicator of poor prognosis in T1, 2, N0, M0 primary breast cancer.
We examined the records of women with primary breast cancer for a history of pregnancy and live births. The patients were all histopathologic T1, 2, N0, M0 white females, untreated post modified radical mastectomy. Patients with a history of interrupted pregnancies have a significantly shorter time to recurrence than those with normal pregnancy history. A trend toward a lower incidence of highly differentiated histological pattern is also observed in cancers from these patients.
D000022:Abortion, Spontaneous / Q000150:complications*; D000328:Adult; D001943:Breast Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008408:Mastectomy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D013997:Time Factors