[Massive hepatic resection for metastatic cancer associated with Dubin-Johnson syndrome. Report of a case].
Massive hepatic resection was carried out on a 42 year-old female who had metastatic lesions of the colonic cancer in right lobe of the liver, which was accompanied by Dubin-Johnson syndrome. The following observations were made. Patient with Dubin-Johnson syndrome tolerated major hepatectomy. As for postoperative regeneration of the liver, there was no difference in comparison with the normal liver. Dubin-Johnson pigments in the hepatocytes decreased in proportion to hepatic regeneration for two months after hepatectomy. Therefore, it might be concluded that Dubin-Johnson syndrome is not poor risk factor for major surgery and massive hepatic resection.
D000328:Adult; D003110:Colonic Neoplasms / Q000601:surgery*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007566:Jaundice, Chronic Idiopathic / Q000150:complications*; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery / Q000648:ultrastructure; D008115:Liver Regeneration; D009364:Neoplasm Recurrence, Local; D001749:Urinary Bladder Neoplasms / Q000556:secondary