A new method for automatic metaphase finding adaptable to different chromosome preparations.
A FORTRAN computer program, running on a Digital PDP 11-34 minicomputer, has been developed for use in conjunction with a Cambridge Quantimet 720 image analyzer for the investigation of metaphase preparations in routine cytogenetics. During a short initiation phase the program is adapted to the type of metaphase being analyzed. The program is fast and its performance is good, even at low microscopic magnifications. It has other uses in biology for all investigations and characterizations of small distinct elements widely spread within a preparation (e.g., autoradiography, bacteriology).
D002871:Chromosome Banding; D002877:Chromosomes, Human; D003201:Computers; D006801:Humans; D008677:Metaphase; D008905:Minicomputers; D012984:Software