title: Nephelometric urinary protein profile as an index of renal involvement in hypertensive disorders of pregnancy.
abstract: Protein analysis was performed on the urine of 62 pregnant women with the use of a nephelometric technique. Thirty-seven women were classified as having mild or severe pregnancy-induced hypertension and/or chronic hypertension. The protein analysis was performed on urine samples obtained prior to delivery and was compared to the degree of proteinuria as determined by the dipstick technique. The degree of immunoglobulinuria increases with increasing severity of pregnancy-induced hypertension while the urine concentration of albumin and transferrin becomes nondetectable. The urinary protein profile appears to be extremely sensitive and accurate in predicting severity of disease.
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000175:diagnosis; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000175:diagnosis*; D007136:Immunoglobulins / Q000652:urine*; D049590:Postpartum Period; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis*; D011507:Proteinuria / Q000175:diagnosis
chemical_list: D007136:Immunoglobulins