title: Rates of entry of alanine and glycerol and their contribution to glucose synthesis in fasted chickens.
abstract: Rates of entry of alanine and glycerol and their contribution to glucose synthesis were studied in 48-h fasted White Leghorn cockerels using primed constant intravenous infusions of L-[U-14C]alanine and [U-14C]glycerol. Entry rates of alanine and glycerol were 112 and 401 mumol/h per kg body weight, respectively. Of the total glucose irreversible loss (entry rate), 1.5 and 6.6% were derived from alanine and glycerol, respectively. The possibilities of the operation of a glyoxylate cycle and omega-oxidation of fatty acids in the fasted chicken are discussed.
mesh_terms: D000409:Alanine / Q000008:administration & dosage / Q000097:blood*; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D002250:Carbon Radioisotopes; D002645:Chickens / Q000378:metabolism*; D005215:Fasting; D005947:Glucose / Q000096:biosynthesis*; D005990:Glycerol / Q000008:administration & dosage / Q000097:blood*; D007263:Infusions, Parenteral / Q000662:veterinary; D008297:Male
chemical_list: D001786:Blood Glucose; D002250:Carbon Radioisotopes; D005947:Glucose; D000409:Alanine; D005990:Glycerol