[Dynamics of brain oxygen saturation under increased pressure].
A mathematical model of the O2 transport within the brain aided to calculate the transitional processes of O2 tension in stepwise increase of the O2 amount in arterial blood as well as in alterations of the main physiological and morphological factors determining the O2 content and its changes in the organs and tissues under these conditions. The mathematical model took into consideration the actual data of mass-transfer in the microcirculation system and was described in the form of differential equations which had been solved by a digital computer with the aid of nets technique. The change of the pO2 mean level within the space of the modelled construction and under the conditions of the stepwise alterations of the above factors, was shown to be actualized during a period of time longer by order than in normoxia. Parameters of the transitional processes of saturation of the brain tissue with oxygen were shown to depend on the O2 content in arterial blood, on the blood flow velocity in capillaries and their density.
D000818:Animals; D001692:Biological Transport; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply / Q000378:metabolism*; D002196:Capillaries / Q000378:metabolism; D004058:Diffusion; D006801:Humans; D006931:Hyperbaric Oxygenation; D008433:Mathematics; D008954:Models, Biological; D010101:Oxygen Consumption; D010313:Partial Pressure; D013997:Time Factors
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