Freeze-fracture study of muscle plasma membrane in obligate carriers of Duchenne muscular dystrophy.
Diminution of intramembranous particles and increase in the number of caveolae have been reported in freeze-fractured muscle plasma membrane of patients with Duchenne muscular dystrophy. We searched for similar alterations in a population of muscle plasma membranes from obligate carriers of Duchenne muscular dystrophy. There were no significant changes in muscle plasma membrane morphology in carriers and normal controls.
D000328:Adult; D002462:Cell Membrane / Q000648:ultrastructure*; D005614:Freeze Fracturing; D006579:Heterozygote; D006801:Humans; D009132:Muscles / Q000648:ultrastructure*; D009136:Muscular Dystrophies / Q000473:pathology*