Neuronal ceroid-lipofuscin storage in a cynomolgus monkey (Macaca fascicularis).
The light and electron microscopical characteristics of non-age-related neuronal ceroid-lipofuscinosis in a young cynomolgus monkey (Macaca fascicularis) are described. The pigment in the neuronal cytoplasm was PAS-positive, sudanophilic, weakly acid-fast, and positive with Schmorl's and aldehydefuchsin stains for lipofuscin. Ultra-structurally, it appeared as membrane-bound, electron-dense aggregates within the cytoplasm of neurones of both brain and spinal cord.
D000818:Animals; D001921:Brain / Q000648:ultrastructure*; D006801:Humans; D008251:Macaca; D008252:Macaca fascicularis; D008297:Male; D008854:Microscopy, Electron; D008992:Monkey Diseases / Q000473:pathology*; D009472:Neuronal Ceroid-Lipofuscinoses / Q000473:pathology / Q000662:veterinary*; D013116:Spinal Cord / Q000648:ultrastructure*