[Role of peripheral adrenoreactive structures in the etiology of disorders of the motor components of rat operant behavior during emotional stress].
It has been found in experiments on rats trained to avoid electric stimulation of the foots by pressing the pedal that previous immobilization and administration of adrenaline and isoprenaline (but not noradrenaline) disturbs the accuracy of the realization of motor components of operant behavior. The total beta-adrenoblockers (but not phentolamine and cardioselective beta 1-adrenoblockers) given in doses which do not cause any central effects reduced the negative action of emotional stress. It is inferred that activation of beta 2-adrenoreceptors of skeletal muscles is likely to play a role in the genesis of disturbed motor skill under emotional stress.
D000818:Animals; D003216:Conditioning, Operant / Q000502:physiology*; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D009048:Motor Skills / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011941:Receptors, Adrenergic / Q000502:physiology*; D013315:Stress, Psychological / Q000503:physiopathology / Q000523:psychology*
D011941:Receptors, Adrenergic; D011433:Propranolol; D007545:Isoproterenol; D004837:Epinephrine
Rol' perifericheskikh adrenoreaktivnykh struktur v realizatsii rasstroĭstv motornykh komponentov operantnoĭ deiatel'nosti krys v usloviiakh émotsional'nogo stressa.