title: Further evidence for a flexible and highly expanded spheroidal model for mucus glycoproteins in solution.
abstract: The flexible and greatly expanded roughly spherical model for mucus glycoproteins proposed earlier, on the basis of hydrodynamic and n.m.r. data, is supported by new hydrodynamic results on a bronchial glycoprotein from a cystic-fibrosis patient. Furthermore, images from electron microscopy of this molecule and a lower-molecular-weight mucus glycoprotein (which closely resembles a glycopolypeptide) appear to be at least consistent with this model.
mesh_terms: D003550:Cystic Fibrosis / Q000378:metabolism; D005260:Female; D006023:Glycoproteins; D006801:Humans; D008854:Microscopy, Electron; D008956:Models, Chemical; D008970:Molecular Weight; D009093:Mucus / Q000032:analysis*; D010048:Ovarian Cysts / Q000378:metabolism; D011487:Protein Conformation
chemical_list: D006023:Glycoproteins