Adrenoleukodystrophy (ALD): clinical and CT features of a childhood variant.
A variant of childhood adrenoleukodystrophy (ALD) affected two male cousins. The characteristic features include a progressive frontal lobe syndrome, frontal pole CT hypodensity, abnormal levels of plasma very-long-chain fatty acids, and a family history consistent with X-linked inheritance.
D000326:Adrenoleukodystrophy / Q000000981:diagnostic imaging*; D002648:Child; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000000981:diagnostic imaging*; D005625:Frontal Lobe / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed