Report on subacute toxicological studies with several fluorocarbons in rats and dogs by inhalation.
The 90-day inhalation studies, conducted in 1975, showed that for the fluorocarbons the lowest toxic concentrations could be regarded above 5,000 ppm by volume of air (0.5% by vol.) when administered to Beagle dogs. With rats the lowest toxic concentrations were above 10,000 ppm by volume. Administration took place on 90 consecutive days for 6 h per day.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001772:Blood Cell Count; D004285:Dogs; D004562:Electrocardiography; D004798:Enzymes / Q000097:blood; D005260:Female; D005466:Fluorocarbons / Q000633:toxicity*; D005740:Gases; D006439:Hemodynamics / Q000187:drug effects; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D004798:Enzymes; D005466:Fluorocarbons; D005740:Gases