Studies on ciliated epithelia of the human genital tract. IV. Mucociliary wave activity in organ cultures of human fallopian tubes challenged with Mycoplasma hominis.
Ciliary activity was studied in specimens of fallopian tube mucosa that were maintained as organ cultures and experimentally infected with Mycoplasma hominis. This activity was quantitated by an established method for recording of the light reflexes from the ridges and troughs in the mucous layer in which the cilia are beating. In organ cultures infected with M. hominis, a ciliostatic effect was observed; the proportion of organ cultures with no detectable ciliary activity was higher and the number of ciliary beats per minute in cultures with detectable activity was lower when M. hominis was present.
D000328:Adult; D002923:Cilia / Q000502:physiology* / Q000648:ultrastructure; D004848:Epithelium / Q000648:ultrastructure; D005187:Fallopian Tubes / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009092:Mucous Membrane / Q000648:ultrastructure; D009175:Mycoplasma Infections / Q000473:pathology*; D009924:Organ Culture Techniques; D012488:Salpingitis / Q000473:pathology*; D013997:Time Factors