[Genetic heterogeneity of myotonic dystrophy].
The results of a long-term study on the mechanism of hereditary transmission in myotonic dystrophy are presented. Thirty-five patients suffering from myotonic dystrophy including 29 with a familial form of the disease and six with a sporadic one were observed. Additionally, detailed information about 135 relatives of the first group patients and 25 of the second group patients was obtained. Most of the patients and some of the relatives were examined by the authors themselves. On the basis of the data obtained, a conclusion is drawn that in some families, myotonic dystrophy may be transmitted according to the dominant whereas in others, according to the recessive type of heredity.
D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D009154:Mutation; D009223:Myotonic Dystrophy / Q000235:genetics*; D010375:Pedigree
Geneticheskaia geterogennost' miotonicheskoĭ distrofii.