[Experimental studies of intraluminal factors influencing gastroesophageal reflux].
A sensor catheter which could measure lower esophageal sphincter pressure (LESP) accurately for a certain period has been long waited. Constantly infused open tip method is most popularly used. However, it is rather difficult to measure LESP continuously by this method because of difficulty of a tip of the catheter in position. Recently, Dent reported a new apparatus called a sleeve sensor for continuous measurement of LESP. We have made and tested a sleeve sensor similar to Dent's. Our studies disclosed that the sleeve sensor was not sensitive enough to measure LESP in children. We designed a different apparatus with a balloon sensor. The detail of the apparatus and the results tested in a LES model and dogs have been reported in this paper. The studies showed that it was sensitive enough to measure LESP. Decrease in sensitivity and inaccuracy due to unstable 0 point for a balloon sensor, have been overcome by elevating the intraballoon pressure continuously and by calibrating at two points.
D000367:Age Factors; D000818:Animals; D004285:Dogs; D004947:Esophagus / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000209:etiology*; D006801:Humans; D008365:Manometry / Q000295:instrumentation*; D008991:Monitoring, Physiologic / Q000295:instrumentation; D009130:Muscle, Smooth / Q000503:physiopathology; D011312:Pressure; D013270:Stomach / Q000503:physiopathology; D014160:Transducers, Pressure