title: Indolamine hallucinogens as MAO inhibitor agents--theoretical approach.
abstract: A new theoretical hypothesis on the mode of action of LSD and other hallucinogens of the indolamine family is proposed. In view of the suggestions that LSD acts both on the 5-HT system as an antagonist and on the DA system as an agonist, we suggest that in addition to 5-HT blocking capacity, LSD and the other indolamine hallucinogens act as MAO inhibitors.
mesh_terms: D000588:Amines / Q000494:pharmacology; D000818:Animals; D006213:Hallucinogens / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology; D008238:Lysergic Acid Diethylamide / Q000494:pharmacology; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D012701:Serotonin / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D000588:Amines; D006213:Hallucinogens; D007211:Indoles; D008996:Monoamine Oxidase Inhibitors; D012701:Serotonin; D008238:Lysergic Acid Diethylamide