title: [Effect of nonsteroid anti-inflammatory agents on the permeability of histohematic barriers].
abstract: It has been demonstrated on male rats that non-steroidal anti-inflammatory drugs change the permeability for 32P of histohematic barriers (HHB) of the internal organs of normal rats and animals with hyperergic inflammation. The nature of the effect appears to be due to the morphological structure of the HHB and blood flow velocity at the organ level. In hyperergic inflammation, HHB permeability for 32P rises 1.5--2-fold. The action of non-steroidal antiphlogistics is organ specific in hyperergic inflammation.
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005921:Glomerulonephritis / Q000188:drug therapy; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014606:Uveitis, Anterior / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents
vernacular_title: Vliianie nesteroidnykh protivovospalitel'nykh sredstv na pronitsaemost' gistogematicheskikh bar'erov.