title: Comparison of turkey luteinizing hormone (LH)- and ovine LH-induced progesterone production in granulosa cells of the turkey (Meleagris gallopavo) and of the domestic fowl (Gallus domesticus).
abstract: Progesterone production was compared in short-term cultures of turkey and fowl granulosa cells isolated from preovulatory follicles of different maturities. In both species cells from the most mature follicle produced the greatest amount of progesterone under stimulated conditions and in response to ovine or turkey LH, the latter being significantly more potent. Whereas basal production of progesterone was higher in turkey cells, the response to LH or cAMP stimulation was significantly greater in chicken granulosa cells both in absolute terms and particularly in relation to unstimulated levels. These species differences may reflect difference in the intensity of reproductive activity of the turkey and the domestic fowl selected for egg production.
mesh_terms: D015124:8-Bromo Cyclic Adenosine Monophosphate / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D002645:Chickens; D005260:Female; D006107:Granulosa Cells / Q000187:drug effects* / Q000378:metabolism; D007986:Luteinizing Hormone / Q000494:pharmacology*; D006080:Ovarian Follicle / Q000502:physiology; D011374:Progesterone / Q000096:biosynthesis*; D012756:Sheep; D013045:Species Specificity; D014422:Turkeys
chemical_list: D015124:8-Bromo Cyclic Adenosine Monophosphate; D011374:Progesterone; D007986:Luteinizing Hormone