Prenatal toxic effects of STS 557. II. Investigation in rabbits--preliminary results.
The synthetic steroid STS 557 (17 alpha-cyanomethyl-17 beta-hydroxy-estra-4, 9-dien-3-one) was tested in gravid rabbits from days 5 to 25 p.c. It was the aim of the experiments to investigate any embryotoxic and/or teratogenic effect of STS 557. The compound did not show any effects on the mothers nor on the fetuses. Levonorgestrel was tested as standard.
D000014:Abnormalities, Drug-Induced / Q000473:pathology; D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects; D004971:Estrus / Q000187:drug effects*; D005260:Female; D005327:Fetal Resorption / Q000139:chemically induced; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000633:toxicity; D011247:Pregnancy; D045167:Progesterone Congeners / Q000633:toxicity*; D011817:Rabbits
D045167:Progesterone Congeners; C023635:dienogest; D009277:Nandrolone