[The effect of new quaternary ammonium compounds on bacteria and fungi. 5: Synthesis of 3-methyl-n-alkylthiomethylpyridinium-, 1-methyl-3-n-alkylthiomethylimidazolium- and 1-ethyl-3-n-alkylthioimidazolinium chloride].
Synthesis of some chlorides indicated in headline and their antibacterial properties was described. Synthesis of quaternary pyridine and imidazoline chlorides was performed by reaction of chloromethyl-n-alkylthioether with 3-methylpyridine or 1-methyl- and 1-ethylimidazole. Antibacterial properties of obtained compounds was tested on 13 strains of bacteria and fungi. Chlorides with dodecyl radical indicated the best antibacterial activity.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D011726:Pyridinium Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011726:Pyridinium Compounds; D000644:Quaternary Ammonium Compounds
Wirkung neuer quartärer Ammoniumverbindungen auf Bakterien und Pilze. Teil 5: Synthese von 3-Methyl-n-alkylthiomethylpyridinium-, 1-Methyl-3-n-alkylthiomethylimidazolinium- und 1-Ethyl-3-n-alkylthiomethylimidazoliniumchloride.