title: Chemical synthesis of nucleotide oligomers: convergent synthesis of fully protected 80mer of thymidylic acid.
abstract: Synthesis of fully protected polythymidylic acids of definite lengths was carried out in solution. Decamer(T10), eicosamer(T20), tetracontamer (T40) and octacontamer(T80) were obtained in 80, 83, 75 and 52% yields respectively by a strategy of convergent synthesis.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D009841:Oligonucleotides / Q000138:chemical synthesis*; D011071:Poly T / Q000138:chemical synthesis*; D011089:Polydeoxyribonucleotides / Q000138:chemical synthesis*
chemical_list: D009841:Oligonucleotides; D011089:Polydeoxyribonucleotides; D011071:Poly T