Cadmium toxicity: inducement of changes in blood and tissue metabolites in fish.
The effects of acute (24 h) and chronic (90 days) cadmium (Cd) poisoning on blood and tissue metabolite levels of a teleost, Puntius conchonius were studied. Significant hyperglycemia with an increment in liver, kidney and ovary cholesterol occurred during acute Cd poisoning. By contrast, an enduring hypoglycemia and diminished levels of tissue cholesterol manifested the chronically intoxicated fish. Both acute and chronic Cd poisoning, however, caused marked hypocholesterolemia, glycogenolysis in liver and brain, and a concomitant rise in myocardium glycogen concentration. Testes cholesterol was found to be depleted after both acute and chronic (60 days) Cd poisoning.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002105:Cadmium Poisoning / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism; D005260:Female; D005399:Fishes / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D010053:Ovary / Q000378:metabolism
D001786:Blood Glucose; D006003:Glycogen; D002784:Cholesterol