The syndrome of bilateral paramedian thalamic infarction.
Bilateral anterior paramedian thalamic infarction resulting from occlusion of a bilaterally distributed thalamosubthalamic paramedian artery was demonstrated on CT in two patients. Patient 1 presented with a transient coma followed by asterixis, hypersomnia, vertical gaze disturbances, profound Korsakoff amnesic syndrome, and a subcortical dementia. Patient 2, with a predominantly right-sided thalamic infarct, showed good recovery from amnesia and vertical gaze disturbances. However, patient 1 remained with severe amnesia and mild subcortical dementia at follow-up 1 year later. These and similar reported cases constitute a lacunar syndrome with characteristic clinical and CT features.
D000647:Amnesia / Q000150:complications; D005123:Eye / Q000503:physiopathology; D006801:Humans; D007238:Infarction / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000503:physiopathology; D011581:Psychological Tests; D013577:Syndrome; D013788:Thalamus / Q000098:blood supply*; D014057:Tomography, X-Ray Computed