Alternaria osteomyelitis. Evidence of specific immunologic tolerance.
A 31-year-old man had a maxillary sinus infection and osteomyelitis. In vitro lymphocyte transformation studies indicated that he had a specific immune tolerance to Alternaria organisms. The etiologic agent was recovered and was identified as Alternaria alternata.
D000328:Adult; D000528:Alternaria / Q000302:isolation & purification*; D000666:Amphotericin B / Q000627:therapeutic use; D006801:Humans; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D008443:Maxillary Sinus; D008825:Miconazole / Q000627:therapeutic use; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D010159:Palate / Q000473:pathology; D012852:Sinusitis / Q000209:etiology
D008825:Miconazole; D000666:Amphotericin B