[Sclerocornea. Ultrastructural and morphologic study].
A 6 month old white male infant had bilateral congenital diffuse sclerocornea. A penetrating keratoplasty was performed in his left eye. Histologic examination by electron microscopy demonstrated: the presence of vacuoles in the superficial epithelial layer, the absence of Bowman's membrane, a disorganization of collagen fibers and lamellae more prominent in the middle stroma, and an extremely thin Descemet's membrane. A comparison, using an automatized image analysis method, was carried out between the stroma of sclerocornea and a normal cornea. Morphometric analysis of the collagenous fibril's diameter and the interfibrillar distances demonstrated a statistically significant difference (p less than 0.001) between the two corneas examined.
D003315:Cornea / Q000002:abnormalities* / Q000648:ultrastructure; D003318:Corneal Opacity / Q000151:congenital* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D012590:Sclera / Q000002:abnormalities*
Sclérocornée. Etude ultrastructurale et morphologique.