Isolation and characterization of elongation factor EF-2 from Guerin tumour.
A homogeneous preparation of EF-2 from Guerin tumour cells was obtained. Its Mr (68 000), pI (6.5), optimum pH (7.0) and amino acid composition are very close to those of rat liver elongation factor. EF-2 from Guerin tumour cells is active in the heterologous liver - tumour system, although half as effective as in the homologous system.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D008099:Liver / Q000032:analysis; D008970:Molecular Weight; D009374:Neoplasms, Experimental / Q000032:analysis*; D020652:Peptide Elongation Factor 2; D010445:Peptide Elongation Factors / Q000302:isolation & purification* / Q000378:metabolism; D051381:Rats
D000596:Amino Acids; D020652:Peptide Elongation Factor 2; D010445:Peptide Elongation Factors