High density of specific GABA binding sites in the human fallopian tube.
The concentration of gamma-aminobutyric acid (GABA) in the human Fallopian tube and the ability of a membrane preparation from the same organ to bind [3H]GABA specifically were examined. A GABA concentration of 177 nM/g frozen tissue was determined and a single population of high-affinity receptor binding sites has been identified in the human oviduct. The density of binding sites demonstrated was as high as in the brain. These results indicate a physiological significance of GABA in the human Fallopian tube.
D000328:Adult; D001665:Binding Sites; D005187:Fallopian Tubes / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014018:Tissue Distribution; D005680:gamma-Aminobutyric Acid / Q000032:analysis / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid