Radioimmunoassay of a cancer-related glycoprotein. Circulating levels.
Circulating levels of (a) tumor-related glycoprotein(s) were determined by radioimmunoassay for a variety of patients and controls, and correlated with sialic acid concentration. Levels were highest in patients with metastatic disease and progressively declined to those with localized disease receiving therapy. Values for normal, adjuvant, and cured patients were significantly lower. Sialic acid concentrations correlated best for the metastatic group but not for the normals.
D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods; D012016:Reference Values; D012794:Sialic Acids / Q000032:analysis
D006023:Glycoproteins; D012794:Sialic Acids