title: Induction of (2'-5')An-dependent endoribonuclease activity by interferon in cultured guinea pig macrophages.
abstract: By a radiobinding assay, an affinity labeling technique, and a column procedure which quantitates mRNA intactness, evidence is presented on the induction of the (2'-5')An-dependent endoribonuclease by interferon in cultured guinea pig macrophages.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004722:Endoribonucleases / Q000096:biosynthesis*; D004790:Enzyme Induction; D006168:Guinea Pigs; D007370:Interferon Type I / Q000494:pharmacology*; D007700:Kinetics; D008264:Macrophages / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D007370:Interferon Type I; D012333:RNA, Messenger; C033547:2'-5'-oligo(A)-dependent endonuclease; D004722:Endoribonucleases