title: Studies on beta-lactam antibiotics. VI. Effect on antibacterial activity of alpha-substituents in the 2-(2-amino-4-thiazolyl)acetyl side chain of a cephalosporin nucleus.
abstract: Synthesis and in vitro antibacterial activity of semisynthetic cephalosporins (I) having an alpha-substituted 2-(2-amino-4-thiazolyl)acetyl side chain at the 7-position were described.
mesh_terms: D002511:Cephalosporins / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
chemical_list: D002511:Cephalosporins