Changes in the effects of stimulation of locus coeruleus and nucleus raphe magnus following dorsal rhizotomy.
The effects of stimulating locus coeruleus (LC) and nucleus raphe magnus (NRM) on lumbar dorsal horn cells that had been denervated by dorsal rhizotomy were studied. Both LC and NRM stimulation inhibited the responses of dorsal horn cells from the side of the cord with intact dorsal roots. However, when cells from the side of the spinal cord that had had prior rhizotomies were studied, half of the units were shown to be activated by either LC or NRM stimulation.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D002415:Cats; D004558:Electric Stimulation; D008125:Locus Coeruleus / Q000502:physiology*; D011903:Raphe Nuclei / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*