Cyclophosphamide, Adriamycin, and platinum chemotherapy in treatment of advanced and recurrent cervical carcinoma.
The chemotherapeutic combination of cyclophosphamide, doxorubicin (Adriamycin), and cis-dichlorodiammineplatinum was used in the treatment of women with metastatic or recurrent cervical carcinomas not amenable to surgery or radiotherapy. A total of 20 patients with evaluable parameters were treated. Three partial remissions and one complete remission were obtained, giving an overall response rate of 20%.
D000230:Adenocarcinoma / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols; D002277:Carcinoma / Q000175:diagnosis / Q000188:drug therapy*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D002945:Cisplatin / Q000008:administration & dosage*; D003520:Cyclophosphamide / Q000008:administration & dosage*; D004317:Doxorubicin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000188:drug therapy*
D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin