A facile synthesis of [3 alpha-3 H]beta -sitosterol.
Direct oxidation of the parent sterol using CrO3 provided (24R)-24-ethyl-5-cholesten-3-one which on treatment with NaBT4 gave [3 alpha-3 H] (24R)-24-ethyl-5-cholesten-3 beta-ol. Purification at each stage afforded samples which were compared spectrally with the corresponding cholesterol series compounds.
D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D007553:Isotope Labeling / Q000379:methods; D010084:Oxidation-Reduction; D012855:Sitosterols / Q000138:chemical synthesis*; D014316:Tritium
D012855:Sitosterols; D014316:Tritium; C025473:gamma-sitosterol