[Effect of an emotionally painful stress on the resistance of the portal vein contractile function to changes in calcium concentration and the effect of anoxia].
The effect of acute anoxia and different concentrations of calcium in the washing solution on spontaneous contractility of isolated portal vein was studied in control and stress-exposed rats. Emotional painful stress resulted in a decrease of vascular smooth muscle resistance to anoxia and in an increase of its sensitivity to the changes of calcium concentrations in the environment. These changes are assumed to be the result of the stress-induced disturbance of energy supply to the myofibrillar contractile apparatus and of the damaged membranous mechanisms of calcium transport.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology*; D011169:Portal Vein / Q000503:physiopathology; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000503:physiopathology*
D002118:Calcium
Vliianie émotsional'no-bolevogo stressa na rezistentnost' sokratitel'noĭ funktsii vorotnoĭ veny k izmeneniiam kontsentratsii kal'tsiia i deĭstviiu anoksii.