[Change in acid phosphatase and N-acetyl-beta-glucosaminidase activity in mouse lymphocytes induced by concanavalin A].
The treatment with concanavalin A (5 micrograms/ml) of mouse lymphocytes containing 70-72% of T cells entails an increase in the activity of acid phosphatase and a decrease in the activity of N-acetyl-beta-glucosaminidase. These changes were detectable 15 h after lymphocyte incubation with Con A. After 24 h of incubation acid phosphatase activity rose 2-fold whereas that of N-acetyl-beta-glucosaminidase dropped 45-50%. Possible mechanisms of these changes are discussed.
D000118:Acetylglucosaminidase / Q000097:blood*; D000135:Acid Phosphatase / Q000097:blood*; D000818:Animals; D003208:Concanavalin A / Q000494:pharmacology*; D006596:Hexosaminidases / Q000097:blood*; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology*; D051379:Mice; D008808:Mice, Inbred CBA
D003208:Concanavalin A; D000135:Acid Phosphatase; D006596:Hexosaminidases; D000118:Acetylglucosaminidase
Izmenenie aktivnosti kisloĭ fosfatazy i N-atsetil-beta-gliukozaminidazy v myshinykh limfotsitakh pod deĭstviem konkanavalina A.