Reductive metabolism and activation of benznidazole, a drug against Chagas' disease.
D000818:Animals; D001711:Biotransformation; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D009593:Nitroimidazoles / Q000378:metabolism*; D009601:Nitroreductases; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D014344:Trypanocidal Agents / Q000378:metabolism*
D009593:Nitroimidazoles; D014344:Trypanocidal Agents; D010088:Oxidoreductases; D009601:Nitroreductases; C009999:benzonidazole