Pentobarbital in refractory status epilepticus.
Tonic-clinic status epilepticus, which is refractory to phenobarbital, phenytoin, and diazepam, may respond readily to a continuous infusion of pentobarbital. The efficacy of pentobarbital can be monitored at the bedside by electroencephalography. We report the clinical and electroencephalographic findings of two children who developed refractory tonic-clonic status epilepticus and responded to pentobarbital.
D002648:Child; D004351:Drug Resistance; D004569:Electroencephalography; D004660:Encephalitis / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D010424:Pentobarbital / Q000627:therapeutic use*; D012202:Reye Syndrome / Q000150:complications; D013226:Status Epilepticus / Q000188:drug therapy* / Q000209:etiology
D010424:Pentobarbital