Dopaminergic nature of feeding-induced behavioral stereotypies in stressed pigeons.
Dopamine dependence of feeding-induced behavioral stereotypies (FIBS) was demonstrated by FIBS facilitation following chronic treatment with a dopamine (DA) agonist, apomorphine, and by FIBS inhibition following the administration of haloperidol, a DA antagonist. However, individuals that emitted FIBS were differentiated from those not emitting FIBS not by assayed telencephalic DA concentrations alone but by a higher stereotyping index (SI), a score positively related to the ratio of telencephalic DA-norepinephrine (NE) concentrations. These latter findings support the hypothesis of Antelman and Caggiula [3] which indicates that a catecholamine interaction in the brain serves to facilitate or inhibit some behavioral actions associated with stress.
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology; D001923:Brain Chemistry / Q000187:drug effects; D010856:Columbidae; D004298:Dopamine / Q000378:metabolism / Q000502:physiology*; D004435:Eating; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D009638:Norepinephrine / Q000494:pharmacology; D013239:Stereotyped Behavior / Q000502:physiology*; D013315:Stress, Psychological / Q000523:psychology*; D013997:Time Factors
D006220:Haloperidol; D001058:Apomorphine; D004298:Dopamine; D009638:Norepinephrine