Pigtailed macaques (Macaca nemestrina) with trisomy X manifest physical and mental retardation.
Three pigtailed macaques (Macaca nemestrina) from a nursery population were predicted to be genetically abnormal based on observations of anatomical and behavioral development. All three exhibited delays in skeletal, visual, intellectual, and social development, suggesting a chromosomal syndrome. Karyotypes showed that two animals were XXX females, and the third was a mosaic XX/XXX female.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000818:Animals; D001835:Body Weight; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D008254:Macaca nemestrina; D009030:Mosaicism; D012729:Sex Chromosome Aberrations; D012917:Social Adjustment; D014314:Trisomy; D014786:Vision Disorders / Q000235:genetics; D014960:X Chromosome