Tuftsin-like activity of amino acids.
The results presented in this paper revealed high or moderate activity of ten out of nineteen amino acids tested. Strong activity stimulating phagocytosis was noted in the presence of leucine, isoleucine, proline, arginine and histidine; moderate in the presence of serine, cysteine, hydroxyproline, aspartic acid and glutamic acid. Alanine, glycine, valine, threonine, phenylalanine, tyrosine, tryptophan, methionine and lysine did not stimulate phagocytic activity of PMN.
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D006168:Guinea Pigs; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D010587:Phagocytosis / Q000187:drug effects*; D013268:Stimulation, Chemical; D013329:Structure-Activity Relationship; D014405:Tuftsin / Q000494:pharmacology*
D000596:Amino Acids; D014405:Tuftsin