Experimental model of hyperlipidemia in rats.
Rats conceived for 14 days high-lipid diet containing coconut oil and cholesterol, given in various doses, separately or in combination, with or without cholic acid. Lipid serum fractions were assayed and lipoproteins were separated by agarose electrophoresis. The model of alimentary hyperlipidemia consisting of feeding rats for 14 days with a diet containing coconut oil (10 g/kg/day), cholesterol (4 g/kg/day) and cholic acid (0.2 g/kg/day) is proposed.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000378:metabolism; D000074263:Coconut Oil; D004032:Diet; D004041:Dietary Fats / Q000378:metabolism; D004195:Disease Models, Animal; D006949:Hyperlipidemias / Q000097:blood*; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008099:Liver / Q000187:drug effects; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010938:Plant Oils; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000097:blood
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D008055:Lipids; D008074:Lipoproteins; D010938:Plant Oils; D014280:Triglycerides; D002784:Cholesterol; D000074263:Coconut Oil