Polarographic determination of butorphanol tartrate.
A new indirect polarographic method is proposed for the determination of butorphanol tartrate in the injectable solution form (Stadol). Direct-current polarography and differential pulse polarography (DPP) were applied for the study of authentic butorphanol and its injectable solution form in alkaline medium after nitration with 1 M potassium nitrite in presence of 1 M hydrochloric acid. The standard addition method was employed for the evaluation of the results and the mean percentage found for the injectable solution form was 99.2 +/- 1.0.
D002077:Butorphanol / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D007267:Injections; D009019:Morphinans / Q000032:analysis*; D011048:Polarography / Q000379:methods; D012996:Solutions / Q000032:analysis
D009019:Morphinans; D012996:Solutions; D002077:Butorphanol