A helix stop signal in the isolated S-peptide of ribonuclease A.
The isolated S-peptide (residues 1-20 of ribonuclease A) is known to show partial alpha-helix formation in aqueous solutions at low temperatures. We show here that the helix is limited to certain residues, including ones that are helical in the intact protein, and that a functional helix termination signal exists in the isolated peptide.
D000595:Amino Acid Sequence; D002942:Circular Dichroism; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D010446:Peptide Fragments; D011487:Protein Conformation; D012260:Ribonucleases; D013329:Structure-Activity Relationship
D010446:Peptide Fragments; D012260:Ribonucleases