[Use of psoralen for detecting the conjugated damage to 2 chains in irradiated phage PM2 DNA].
Using psoralen for the photochemical cross-linking of DNA chains the authors have demonstrated the formation of conjugated lesions, of both opposite and non-opposite types, in X-irradiated superhelical DNA of PM2 phage. It is suggested that these lesions result from hitting a DNA molecule by a spur.
D001435:Bacteriophages / Q000187:drug effects / Q000528:radiation effects*; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D004260:DNA Repair / Q000187:drug effects / Q000528:radiation effects*; D004278:DNA, Superhelical / Q000528:radiation effects*; D004279:DNA, Viral / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D011564:Furocoumarins / Q000494:pharmacology*; D010777:Photochemistry
D003432:Cross-Linking Reagents; D004278:DNA, Superhelical; D004279:DNA, Viral; D011564:Furocoumarins
Ispol'zovanie psoralen dlia obnaruzheniia sopriazhennykh povrezhdeniĭ dvukh tsepeĭ v obluchennoĭ DNK faga PM2.