Considerations for monitoring and evaluating treatment effects in clinical trials.
The efficacies of various treatments commonly are evaluated and compared using prospective clinical trials. For ethical reasons, data from these trials are analyzed on an interim basis. The statistical test procedures used in these evaluations must be carefully selected and appropriately applied.
D002986:Clinical Trials as Topic; D006801:Humans; D008954:Models, Biological; D009026:Mortality; D013223:Statistics as Topic