title: Reduction of postoperative vomiting in high-risk patients.
abstract: Twenty-eight patients who had a history of severe postoperative vomiting were divided into two groups. The first group received various anaesthetic drugs and the second group received a pethidine promethazine premedication and thiopentone, alcuronium, fentanyl and droperidol. There was a significant reduction in postoperative vomiting as assessed by vomiting score in both groups of patients, with the second group having a greater reduction in vomiting score than the control group. Nine of the patients in the second group have received the same anaesthetic uneventfully on a subsequent occasion. We propose that reassurance and the anaesthetic technique described can significantly reduce the incidence of postoperative vomiting in a high risk group.
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects; D004338:Drug Combinations; D006801:Humans; D008614:Meperidine; D010817:Physician-Patient Relations; D011183:Postoperative Complications / Q000517:prevention & control; D011229:Preanesthetic Medication; D011398:Promethazine; D012306:Risk; D014839:Vomiting / Q000517:prevention & control*
chemical_list: D004338:Drug Combinations; D008614:Meperidine; D011398:Promethazine