Glucose dehydrogenase in teleosts: tissue distribution and proposed function.
Tissue extracts of skeletal muscle, heart, eye, brain, liver, kidney, gill and stomach were electrophoretically examined for glucose dehydrogenase (EC 1.1.1.47) activity in 21 species of marine teleost fishes. Glucose dehydrogenase expression was detected only in liver extracts. Considerable interordinal variation was found in levels of enzymatic activity. Available data support the hypothesis that glucose dehydrogenase provides NADPH for the mixed-function oxidase system in teleosts.
D000818:Animals; D002237:Carbohydrate Dehydrogenases / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D005948:Glucose Dehydrogenases / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D013045:Species Specificity; D014018:Tissue Distribution
D009249:NADP; D006899:Mixed Function Oxygenases; D002237:Carbohydrate Dehydrogenases; D005948:Glucose Dehydrogenases