The effect of arginine vasotocin on prostaglandin production of the hen uterus.
The effect of arginine vasotocin (AVT) on prostaglandin (PG) production by the hen uterus (shell gland) in vitro was investigated. It was found that AVT caused uterine contractions as well as PG release from the uteri. In uterine homogenates, which lack the functional integrity for mechanical contractions, AVT also caused an increase in PG biosynthesis. It seems likely that the PG-releasing response to AVT is not a secondary effect of uterine contractions but a specific action of AVT.
D000818:Animals; D002645:Chickens / Q000502:physiology; D005260:Female; D066298:In Vitro Techniques; D011453:Prostaglandins / Q000096:biosynthesis* / Q000378:metabolism; D014590:Uterine Contraction / Q000187:drug effects; D014599:Uterus / Q000187:drug effects* / Q000378:metabolism; D014668:Vasotocin / Q000494:pharmacology*
D011453:Prostaglandins; D014668:Vasotocin