title: Simian AIDS: isolation of a type D retrovirus and transmission of the disease.
abstract: A type D retrovirus related to but distinct from Mason-Pfizer monkey virus was isolated in vitro from the blood of two rhesus monkeys (Macaca mulatta) with simian acquired immunodeficiency syndrome (SAIDS). Three juvenile rhesus monkeys that were injected intravenously with tissue culture fluids containing this virus developed SAIDS after 2 to 4 weeks.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D004195:Disease Models, Animal; D005260:Female; D008251:Macaca / Q000382:microbiology*; D008253:Macaca mulatta / Q000382:microbiology*; D008297:Male; D012190:Retroviridae / Q000276:immunology / Q000302:isolation & purification* / Q000648:ultrastructure; D014758:Viral Core Proteins; D014759:Viral Envelope Proteins / Q000276:immunology; D014764:Viral Proteins / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D014758:Viral Core Proteins; D014759:Viral Envelope Proteins; D014764:Viral Proteins