title: Idiotypic inheritance: allelic relationships between immunoglobin genes.
abstract: An analysis of genes related to the expressed VH region of anti-NP antibodies in C57BL/6 mice showed that 24 distinct genes could be grouped into 3 subfamilies. Some of these genes showed striking homology with a family found in BALB/c mice. The extension of diversity through gene conversion seems to be very important in the VH family.
mesh_terms: D000483:Alleles; D000818:Animals; D003001:Cloning, Molecular; D005796:Genes; D007130:Immunoglobulin Idiotypes / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C / Q000235:genetics; D008810:Mice, Inbred C57BL / Q000235:genetics
chemical_list: D007130:Immunoglobulin Idiotypes