title: Consumption of a low protein diet increases norepinephrine turnover in brown adipose tissue of adult rats.
abstract: Adult rats were fed diets containing 5 or 15% casein to determine effects of low protein intake on efficiency of energy retention and on brown adipose tissue metabolism. Efficiency of energy retention of rats fed the 5% casein diet for 4 or 8 weeks was approximately 40% lower than was efficiency of energy retention of rats fed the 15% casein diet. Rats fed the 5% casein diet also exhibited an enhanced norepinephrine (NE)-stimulated metabolic rate and an accelerated NE turnover in their brown adipose tissue relative to responses of rats fed the 15% casein diet. Additionally, NE turnover in white adipose tissue, but not heart, was accelerated in rats fed the 5% casein diet. The reduced efficiency of energy retention in rats fed the low protein diet may be linked to accelerated NE turnover and heat production by their brown adipose tissue.
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001833:Body Temperature Regulation; D004044:Dietary Proteins / Q000008:administration & dosage*; D004734:Energy Metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D010101:Oxygen Consumption; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004044:Dietary Proteins; D009638:Norepinephrine