title: [Characteristics of the adrenal endocrine function of Papio hamadryas in the metopyrone test].
abstract: Hormonal function of the adrenals of preadolescent and adult monkeys (Papio hamadryas) was examined by the metopyrone test. After a single injection of metopyrone the content of cortisol, 11-deoxycortisol, progesterone, pregnenolone, 17-hydroxyprogesterone and 17-hydroxypregnenolone was measured in the blood of monkeys by radioimmunoassay. The reasons for age-associated differences in the hormonal response of the primate adrenals to metopyrone injection are discussed. The conclusion is drawn on the advisability of a single metopyrone injection for studying functional reserves of the pituitary-adrenal system.
mesh_terms: D000304:Adrenal Cortex Function Tests / Q000379:methods; D000305:Adrenal Cortex Hormones / Q000097:blood; D000311:Adrenal Glands / Q000187:drug effects*; D000375:Aging / Q000187:drug effects; D000818:Animals; D008297:Male; D008797:Metyrapone / Q000494:pharmacology*; D010215:Papio / Q000502:physiology*; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D008797:Metyrapone
vernacular_title: Kharakteristika éndokrinnoĭ funktsii nadpochechnykh zhelez pavianov gamadrilov v usloviiakh metopironovogo testa.