title: [Macrofocal metabolic myocardial damage].
abstract: Eighteen observations of large-focal damage of the myocardium are analysed which macroscopically simulated myocardial infarction. Histologically the foci were represented by confluent areas of fatty and albuminous degeneration alternating with necrosis of individual cardiomyocytes. This condition is a complication of diseases having signs of intoxication, anemia, disorders of lipid metabolism and water-electrolyte balance combined with ischemic heart disease. The degree of heart function disturbance correlated with both the severity of concurrent diseases and the depth and size of cardiomyocyte damage.
mesh_terms: D000328:Adult; D000368:Aged; D003402:Creatine Kinase / Q000097:blood; D003937:Diagnosis, Differential; D004719:Endomyocardial Fibrosis / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009124:Muscle Proteins / Q000378:metabolism; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*
chemical_list: D009124:Muscle Proteins; D003402:Creatine Kinase
vernacular_title: O krupnoochagovom metabolicheskom povrezhdeniĭ miokarda.