Changes in the activities of S-adenosylmethionine synthetase isozymes from rat liver with dietary methionine.
The activities of S-adenosylmethionine synthetase isozymes in liver were measured after rats received a diet containing excess methionine. The activity of the alpha-form increased with increasing methionine content in the diet, and reached 4-5 fold after 6 days on a 3% methionine diet. However, the activity of the beta-form showed only a 1.5 fold increase. The activity of the gamma-form in kidney showed no significance change.
D000818:Animals; D004032:Diet; D007527:Isoenzymes / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008715:Methionine / Q000494:pharmacology*; D008716:Methionine Adenosyltransferase / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014166:Transferases / Q000378:metabolism*
D007527:Isoenzymes; D008715:Methionine; D014166:Transferases; D008716:Methionine Adenosyltransferase