Unsuspected extra-abdominal sites of infection: scintigraphic detection with indium-111-labeled leukocytes.
Scintigraphy with indium-111-labeled leukocytes (In-111-WBC) was assessed in 128 patients with suspected abdominal-pelvic abscesses. Studies were positive in 37 of 41 patients with proved abscesses, in two of two with infected aortic grafts, and in 12 of 15 with other infections; studies were negative in 63 of 70 cases without infection. The sensitivity of leukocyte scintigraphy in this series was 88%, specificity 90%, and accuracy 89%. Sixteen percent of all patients studied with In-111-WBC scintigraphy had unexpected sites of infection outside the abdomen. Of the 58 patients with proved infection, 20 (34%) had alterations in diagnostic evaluations and therapeutic regimens due to such findings.
D000005:Abdomen / Q000000981:diagnostic imaging; D000038:Abscess / Q000000981:diagnostic imaging*; D006801:Humans; D007204:Indium; D007239:Infections / Q000000981:diagnostic imaging*; D007962:Leukocytes; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012189:Retrospective Studies
D011868:Radioisotopes; D007204:Indium