Further look at dextropropoxyphene with or without paracetamol in the treatment of arthritis.
The analgesic effects of dextropropoxyphene and paracetamol and that of a combination of the two drugs were assessed in 24 patients who suffered from either rheumatoid arthritis or osteoarthritis. Dextropropoxyphene, which had a marginal effect on pain score, led to a more significant effect on patient well-being, particularly when it was the first drug given in the sequence. The addition of paracetamol had more of a negative than a positive effect on pain score and well-being.
D000082:Acetaminophen / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D011431:Dextropropoxyphene / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D004341:Drug Evaluation; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy*; D010146:Pain / Q000188:drug therapy
D004338:Drug Combinations; D000082:Acetaminophen; D011431:Dextropropoxyphene