Shortened long-term survival of incompatible red cells in a patient with anti-McCoy-like antibody. Immunoglobulin characteristics of this antibody.
The long-term survival of incompatible 51Cr-labeled red cells in a patient with a high titer, low avidity antibody of anti-McCoy-like specificity was decreased (half-life = 14 days), although the 24-hour survival was normal (91.9%). This antibody was composed of IgA and IgG, the latter consisting of subclasses 1, 3, and 4.
D000368:Aged; D001789:Blood Group Antigens / Q000276:immunology*; D001787:Blood Group Incompatibility / Q000097:blood* / Q000276:immunology; D004905:Erythrocyte Aging; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007518:Isoantibodies / Q000096:biosynthesis*
D001789:Blood Group Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007518:Isoantibodies