Toxicity of handcleaners.
The irritancy of commercially available liquid handcleaners was determined by means of soap chamber test (with Big Finn Chambers). This in vivo method appeared to registrate the irritant effects of the cleaners very well. Several alkaline soaps were tested in addition to surfactants and soaps with a neutral or low pH. Alkaline soaps were not extra irritating than other handcleaners. The cleaner with the highest irritancy score had a low pH. It was concluded that the pH was not a useful parameter to predict the irritancy of handcleaners.
D003902:Detergents / Q000633:toxicity*; D004890:Erythema / Q000139:chemically induced; D006225:Hand; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012867:Skin / Q000187:drug effects*; D012871:Skin Diseases / Q000139:chemically induced; D012915:Soaps / Q000633:toxicity*; D013501:Surface-Active Agents / Q000633:toxicity*
D003902:Detergents; D012915:Soaps; D013501:Surface-Active Agents