[Fat absorption following temporary ischemia of the small intestine].
Ischemia of the rat small intestine lasting 40 min leads to pronounced structural disorders in lipid transport across the enterocytes, reduction in enzymatic activity of the cells and in absorption function, and to the loss of fat with feces. The normalization of the indicated parameters occurs at varying times and ends after 1 month. Fat transport abnormality is marked by an increase in lipid drops in the cavities of the smooth endoplasmic network, appearance of large and numerous matrix lipids, by a greater reduction, as compared to normal, in the membranes of the rough endoplasmic network and lamellar complex in the epithelium of the villi. Accumulation of lipids and retardation of their release from the cytoplasm are determined by incomplete differentiation of the epithelium, which is also combined with a decreased enzymatic activity.
D000818:Animals; D005243:Feces / Q000378:metabolism; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000098:blood supply* / Q000378:metabolism / Q000648:ultrastructure; D007511:Ischemia / Q000378:metabolism* / Q000473:pathology; D050356:Lipid Metabolism; D051381:Rats; D013997:Time Factors
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