title: Occurrence of a cohort phenomenon in peptic ulcer mortality from Switzerland.
abstract: The present study was undertaken to examine whether the cohort phenomenon of peptic ulcer mortality is unique to the British population or whether it is a common feature of peptic ulcer disease. The occurrence of a cohort phenomenon was also found in data on peptic ulcer mortality from Switzerland. Swiss birth-cohorts born around 1870 and 1900 had been exposed to a maximum risk of dying of gastric and duodenal ulcer, and they carried this risk throughout their lives. By the time lag between both ulcer types, a common early determinant precipitating both diseases is made unlikely. The British cohort phenomenon was thought to result from high-risk birth-cohorts suffering mostly from the early phase of urbanization, World War I, and world economic crisis. This explanation, however, does not pertain to the high-risk cohorts from Switzerland. The nature of the determinants of peptic ulcer that occur early in the life of a cohort remains unknown.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005860:Germany, West; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000401:mortality*; D012737:Sex Factors; D013557:Switzerland; D006113:United Kingdom