title: Rectification of distorted chromosome image: automatic determination of density profiles.
abstract: In this study, we present a new method of the rectification of distorted chromosome image allowing a more accurate description of the chromosome by obtaining density profiles with a large choice of scan axes, and an automatic centromere localisation and determination of the centromeric index.
mesh_terms: D002503:Centromere / Q000648:ultrastructure*; D002871:Chromosome Banding; D002875:Chromosomes / Q000648:ultrastructure*; D003201:Computers; D006801:Humans; D007621:Karyotyping / Q000379:methods; D008433:Mathematics; D010363:Pattern Recognition, Automated