Vasopressin promotes the metabolism of near-physiological concentration of glutamine in isolated rat liver cells.
In isolated rat liver cells, vasopressin, like glucagon, promotes the metabolism of glutamine used at near-physiological concentration (1 mM). These findings indicate that, in vivo, both hormones might participate in the control of hepatic gluconeogenesis and ureogenesis from glutamine.
D000818:Animals; D002118:Calcium / Q000494:pharmacology; D005934:Glucagon / Q000494:pharmacology; D005943:Gluconeogenesis / Q000187:drug effects; D005973:Glutamine / Q000378:metabolism*; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014508:Urea / Q000378:metabolism; D014667:Vasopressins / Q000494:pharmacology*
D005973:Glutamine; D014667:Vasopressins; D014508:Urea; D005934:Glucagon; D002118:Calcium