Fibroblastic activities post implantation of cobalt chromium alloy and pure germanium in rabbits.
Different preimplantation surface finishes were applied to surgical vitallium discs and germanium prisms implanted for 20 days within the back muscles of adult rabbits. Histopathologic analysis of the numbers of nuclei of active fibroblasts immediately adjacent to the implants was carried out. The mean apparent volume fractions (MAVF) for the subdermal implant sites were found to depend on the surface cleanliness of the implant, the cleanest or highest-surface-energy surfaces giving the highest MAVF values for active fibroblasts.
D000818:Animals; D002858:Chromium Alloys / Q000009:adverse effects*; D005347:Fibroblasts / Q000473:pathology; D005857:Germanium / Q000494:pharmacology*; D019736:Prostheses and Implants; D011817:Rabbits
D002858:Chromium Alloys; D005857:Germanium