[The effect of a tar admixture to dithranol-salicylic-acid-white-petrolatum therapy on the cytokinetics of psoriasis].
The initial stimulation of DNA-synthesis after application of dithranol as single agent is completely inhibited by addition of tar. The autoradiographic analyse indicates that the good clinical effect of the new antipsoriatic therapy with TCSV may be due to suppression of dithranol-caused irritation by tar. But, restored cytokinetic values do not correspond to clinical remission of psoriasis.
D000293:Adolescent; D000328:Adult; D000873:Anthracenes / Q000008:administration & dosage*; D000875:Anthralin / Q000008:administration & dosage*; D001345:Autoradiography; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010577:Petrolatum / Q000008:administration & dosage*; D011565:Psoriasis / Q000188:drug therapy*; D012459:Salicylates / Q000008:administration & dosage*; D013638:Tars / Q000008:administration & dosage* / Q000378:metabolism
D000873:Anthracenes; D004338:Drug Combinations; D012459:Salicylates; D013638:Tars; D010577:Petrolatum; D000875:Anthralin
Einfluss von Teerzusatz zur Cignolin-Salicylsäure-weisse-Vaselin-Therapie (CSV) auf die Zytokinetik der Psoriasis (TCSV-Therapie).