Pharmacology of steroid receptors: from molecular and cellular studies to efficient antihormonal drugs.
This paper reviews the current state of steroid receptor research, mostly on the basis of the work accomplished in the author's laboratory. New results on the structure of these receptors, on their functioning and on their immunology are reported. Several aspects of antioestrogen and antiprogesterone activities and mechanism of action are also reviewed, in the view of their clinical use.
D000818:Animals; D005260:Female; D006727:Hormone Antagonists / Q000494:pharmacology*; D006728:Hormones / Q000494:pharmacology; D006801:Humans; D011247:Pregnancy; D011494:Protein Kinases / Q000032:analysis; D011980:Receptors, Progesterone / Q000302:isolation & purification; D011987:Receptors, Steroid / Q000032:analysis* / Q000187:drug effects / Q000502:physiology
D006727:Hormone Antagonists; D006728:Hormones; D011980:Receptors, Progesterone; D011987:Receptors, Steroid; D011494:Protein Kinases