Verapamil poisoning in an infant.
An 11-month-old female infant accidentally ingested 400 mg of verapamil. The patient developed coma, seizures, respiratory depression, bradycardia, and hypotension. Seizures have not previously been described in association with verapamil therapy or poisoning. She was successfully resuscitated with intravenous normal saline, calcium chloride, isoproterenol, and dopamine. A description of some of the manifestations of verapamil poisoning is given, and suggestions are made for several modalities of treatment, with emphasis on the use of intravenous calcium.
D001919:Bradycardia / Q000139:chemically induced; D002122:Calcium Chloride / Q000627:therapeutic use; D003128:Coma / Q000139:chemically induced; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007223:Infant; D012131:Respiratory Insufficiency / Q000139:chemically induced; D012640:Seizures / Q000139:chemically induced; D014700:Verapamil / Q000506:poisoning*
D014700:Verapamil; D002122:Calcium Chloride