title: Early histological changes in acute necrotizing hemorrhagic pancreatitis. A retrospective pathological study of 20 total pancreatectomy specimens.
abstract: Settled lesions of acute necrotizing hemorrhagic pancreatitis have been commonly reported. Early alterations remained unknown. In a retrospective pathological study of 20 total pancreatectomy specimens, early changes have been evidenced in "grossly unmodified" areas of pancreas: acinar cells homogenization, ductal dilatation with epithelial degeneration, diffuse interstitial edema and fibroblastic reaction, necrotic angeitis . These alterations were identical to the changes described in experimental studies.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D004487:Edema / Q000473:pathology; D005260:Female; D006470:Hemorrhage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010180:Pancreatectomy; D010195:Pancreatitis / Q000473:pathology*; D012189:Retrospective Studies; D013997:Time Factors