Effect of microcapsule core-wall ratio and aggregate size on the properties of tableted microcapsules.
Microcapsules containing sodium phenobarbital cores and ethylcellulose walls have been tableted. The thickness of the tablets, the breaking strength, and the dissolution characteristics were studied and found to be affected by the microcapsule core-wall ratio and the size of the microcapsule aggregates.
D002626:Chemistry, Pharmaceutical; D006244:Hardness; D010316:Particle Size; D010634:Phenobarbital / Q000008:administration & dosage; D012995:Solubility; D013607:Tablets
D013607:Tablets; D010634:Phenobarbital