Case report: acute hemorrhagic multifocal angioencephalopathy.
A 53-year-old chronic alcoholic male developed an acute febrile, fulminant fatal encephalopathy which lasted 2.5 weeks. Necropsy showed focal, acute hemorrhagic necrotizing lesions of the diencephalon, cingulate gyrus, and amygdala, apparently due to a vasculopathy involving mainly small veins. The case is unique, but the pathology is somewhat similar to an idiopathic disorder described as subacute diencephalic angioencephalopathy [DeGirolami et al. 1974, Kinney et al. 1980].
D000679:Amygdala / Q000473:pathology; D001253:Astrocytes / Q000648:ultrastructure; D001929:Brain Edema / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000473:pathology*; D002544:Cerebral Infarction / Q000473:pathology*; D004027:Diencephalon / Q000473:pathology; D004660:Encephalitis / Q000473:pathology*; D006179:Gyrus Cinguli / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009336:Necrosis