Qualitative platelet dysfunction following cancer chemotherapy: a case report.
A case of qualitative platelet dysfunction following cancer chemotherapy is documented. Besides the numerical reduction defect, there appear to be functional changes in the platelets leading to bleeding diathesis. The present case was thoroughly evaluated, and it was observed that there is suppression of the platelet functions in a patient receiving cancer chemotherapy, a combination of cyclophosphamide, methotrexate, and 5-fluorouracil.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects*; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006474:Hemorrhagic Disorders / Q000097:blood / Q000139:chemically induced*; D006801:Humans