title: Central serous chorioretinopathy complicating systemic corticosteroid treatment.
abstract: Central serous chorioretinopathy developed in 2 cases of retrobulbar neuritis during systemic treatment with corticosteroids. Fluorescein angiography confirmed leakage surrounded by central serous detachment of the retina. In one case the central serous chorioretinopathy recurred 3 times during 3 separate courses of treatment. Spontaneous recovery accompanied a reduction in steroid treatment to a low level. It is suggested that high dosage corticosteroids may damage the posterior blood-ocular barrier.
mesh_terms: D000328:Adult; D001623:Betamethasone / Q000009:adverse effects*; D002829:Choroid / Q000187:drug effects*; D006801:Humans; D008297:Male; D009902:Optic Neuritis / Q000188:drug therapy; D012163:Retinal Detachment / Q000139:chemically induced; D012164:Retinal Diseases / Q000139:chemically induced*; D014603:Uveal Diseases / Q000139:chemically induced
chemical_list: D001623:Betamethasone