title: A longitudinal study of handgrip and dementia in older people.
abstract: Handgrip was measured, using a modified sphygmomanometer cuff, in a random sample of 487 older people in Edinburgh in 1968-9. The prevalence of dementia was determined by full psychiatric examination. The error score in the Isaacs-Walkey test was also recorded. Five years later, 261 of the original sample were re-examined. In both examinations treated cross-sectionally there was a significant decrease in grip strength as age increased. However, the mean of the five-year change in individuals did not differ significantly from zero and was not related to age. Handgrip was not significantly related to dementia either at the first examination or as a predictor of new dementia at the five-year examination. Mean handgrip was significantly less at the first examination in those who subsequently died, compared with five-year survivors.
mesh_terms: D000368:Aged; D003704:Dementia / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007537:Isometric Contraction; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D012606:Scotland