The metabolical effects of L-carnitine in angina pectoris.
We determined the effects of L-carnitine on myocardial metabolism in 18 patients with angiographically-proven coronary artery disease, subjected to two rapid coronary sinus pacing evaluations. L-Carnitine converted lactate production to extraction and increased the percentage of free fatty acid extraction. These results suggest that L-carnitine may be of use to improve the metabolism of coronary artery disease patients.
D000787:Angina Pectoris / Q000378:metabolism*; D001786:Blood Glucose / Q000378:metabolism; D002331:Carnitine / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D006801:Humans; D007773:Lactates / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007773:Lactates; D002331:Carnitine