Labile coagulation factors in thawed fresh frozen plasma prepared by two methods.
Two preparations of fresh frozen plasma were studied. The plasma from CPDA-1 whole blood units was either frozen within 6 h (FFP-I) or 18-20 h (FFP-II) of phlebotomy. Average activity for factor VIII for FFP-I (n = 6) and FFP-II (n = 19) was 102% and 55%, respectively (p less than 0.01). Average activity for factor V and VII in both products was approximately 100%. Factor XI activity (n = 13) in FFP-II averaged 84%. We conclude that FFP-I and FFP-II are equivalent in terms of coagulation factor activity except for factor VIII.
D001779:Blood Coagulation Factors / Q000302:isolation & purification*; D001793:Blood Preservation / Q000379:methods*; D005615:Freezing; D006801:Humans; D010949:Plasma; D013997:Time Factors
D001779:Blood Coagulation Factors