title: Transferability studies for the AACC reference method and the IFCC method for measurement of alkaline phosphatase activity.
abstract: We present the results of measurements of alkaline phosphatase activity from interlaboratory transferability studies conducted by 12 laboratories in five countries. The variability, as demonstrated by within-day precision (CV less than or equal to 2.6%), between-day precision (CV less than or equal to 3.6%), and between-lab precision (CV less than or equal to 6.3%) establishes the transferability of this method for alkaline phosphatase. Some common errors encountered in enzyme measurements that affect the accuracy and precision of the measurements are listed.
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D001322:Autoanalysis; D005069:Evaluation Studies as Topic; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007753:Laboratories; D012016:Reference Values; D013696:Temperature
chemical_list: D000469:Alkaline Phosphatase