Evidence for TSH autoregulation of thyroid carcinoma.
Presumptive evidence for TSH dependency of thyroid hormone secretion from metastatic thyroid cancer is presented. In the patient described, the metastatic tumor was the only source of thyroid hormone production which was adequate enough to maintain the patient euthyroid. Tumor secretion of thyroid hormone appeared to regulate the TSH drive so that euthyroidism was maintained in the face of increasing tumor mass.
D000230:Adenocarcinoma / Q000378:metabolism* / Q000556:secondary; D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism* / Q000556:secondary; D008297:Male; D013960:Thyroid Function Tests; D013964:Thyroid Neoplasms / Q000378:metabolism; D013972:Thyrotropin / Q000378:metabolism*
D013972:Thyrotropin