Long survival in subacute sclerosing panencephalitis.
A case is reported of a boy who at the age of 14 years developed subacute sclerosing panencephalitis. He deteriorated over a period of 9 months, improved greatly and remained stable for 7 years before relapse. The final deterioration to death extended over 6 years. During the whole period he was examined regularly and the electroencephalogram recorded at 3 to 6 monthly intervals. The brain was examined histologically after death. Electroencephalographic and pathological features are described.
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D004569:Electroencephalography; D005071:Evoked Potentials; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009186:Myelin Sheath / Q000473:pathology; D009410:Nerve Degeneration; D009454:Neurofibrils / Q000648:ultrastructure; D009457:Neuroglia / Q000648:ultrastructure; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis / Q000473:pathology*; D013378:Substantia Nigra / Q000473:pathology