title: [Akrokeratoderma hereditarium punctatum].
abstract: Akrokeratoderma hereditarium punctatum is characterized by multiple, skin coloured papules on the dorsum of the hands, which develop as verrucous lesions after puberty and spread slowly in the following years. There is no subjective discomfort. Focal hyperkeratosis and hypergranulosis are histological markers; the elastic fibers appear normal. The differential diagnosis of similar keratosis of the palms and soles is discussed.
mesh_terms: D005260:Female; D006229:Hand Dermatoses / Q000235:genetics*; D006801:Humans; D007642:Keratosis / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged
vernacular_title: Akrokeratoderma hereditarium punctatum.