Plasma growth-promoting activity measured as thymidine activity in constitutionally short children.
Growth-stimulating activity of plasma was measured, both as thymidine activity using a lymphocyte bioassay and as sulfation activity using a cartilage bioassay, in 72 constitutionally short children aged 1-6 years and 38 age-matched controls. Plasma transferrin was also measured. No significant differences were found between the two groups. However, short children aged 1-3 years did not have higher thymidine activity than children aged 4-10 years, whereas in normals the thymidine activity was significantly higher in the first years of life. Thymidine activity was lower in female than in male constitutionally short children.
D000293:Adolescent; D000365:Age Determination by Skeleton; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000097:blood; D006801:Humans; D007223:Infant; D008297:Male; D013002:Somatomedins / Q000097:blood*; D013936:Thymidine / Q000097:blood*; D014168:Transferrin / Q000032:analysis*
D013002:Somatomedins; D014168:Transferrin; D013936:Thymidine