title: The role of nonstress tests, fetal biophysical profile, and contraction stress tests in the outpatient management of insulin-requiring diabetic pregnancies.
abstract: Antepartum fetal surveillance methods applicable in a home glucose-monitored population of pregnant diabetic women have been evaluated. A testing sequence of nonstress heart rate testing, backed up by either the fetal biophysical profile or contraction stress testing employed at a twice weekly interval, in 107 outpatients was compared with the management of 140 historic control patients by weekly nonstress tests and daily plasma estriols. There were 617 of 672 (91.8%) reactive nonstress tests in outpatients compared to 566 of 626 (90.4%) reactive tests in hospitalized control patients. Of 13 contraction stress tests performed in the outpatient group, only one was positive. Although 2,670 estriol determinations were done on hospitalized control patients, none was used for outpatients. No losses were attributed to unexplained antenatal stillbirth in either group. A fetal biophysical score of 8 was found to be at least as reliable as a reactive nonstress test. Antenatal surveillance in the well-controlled, insulin-requiring diabetic woman can be safely achieved with a testing sequence that consists of twice weekly nonstress tests backed up by the fetal biophysical profile and contraction stress tests.
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology / Q000628:therapy*; D004964:Estriol / Q000032:analysis; D005260:Female; D005318:Fetal Heart / Q000502:physiology; D005323:Fetal Monitoring; D005333:Fetus / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D014590:Uterine Contraction
chemical_list: D004964:Estriol