title: [Acetylation processes in chronic alcoholics].
abstract: The activity of N-acetyltransferase was investigated in chronic alcoholics by the intensity of sulfadimezine acetylation. The activity of the enzyme was shown to vary with the stage of the disease. As compared with control, patients with Stage II disease exhibited the predominance of "rapid" acetylators (60%) whilst a significant fall in the number of "rapid" acetylators (from 60% to 36%) was detected in Stage II disease.
mesh_terms: D000107:Acetylation; D000123:Acetyltransferases / Q000378:metabolism*; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000201:enzymology*; D001711:Biotransformation; D006801:Humans; D008297:Male; D008875:Middle Aged; D013418:Sulfamethazine / Q000378:metabolism*
chemical_list: D013418:Sulfamethazine; D000123:Acetyltransferases
vernacular_title: Protsessy atsetilirovaniia u bol'nykh khronicheskim alkogolizmom.