Membrane structural alterations in malignant and normal avian lymphocytes: a Raman investigation.
Resonance and nonresonance Raman spectra have been obtained from neoplastically transformed and normal avian lymphocytes. The acyl chains of membrane phospholipids of neoplastic cells are more highly unsaturated than those of normal cells. The observation of prominent carotenoid bands in both cell populations indicates the availability of a sensitive, intrinsic probe of membrane potential and local membrane environment.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D002645:Chickens / Q000097:blood*; D005260:Female; D008214:Lymphocytes / Q000473:pathology*; D008380:Marek Disease; D008563:Membrane Lipids / Q000378:metabolism; D013059:Spectrum Analysis, Raman
D008563:Membrane Lipids