[Effect of porcine calcitonin on pain caused by cancer-induced bone destruction].
The analgesic effect of porcine calcitonin (PCT) was studied in 32 patients with cancer-induced bone destruction. Twenty patients (62.5%) showed some response among them 10 of 13 patients who had suffered from uncontrollable pain despite other treatment methods such as radiotherapy, and or the administration of other analgesics. The effect was observed about 10 days after the administration of the drug. Combined therapy with PCT and other modalities such as radiotherapy, chemotherapy and hormone therapy had a marked effect in controlling the pain.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology / Q000503:physiopathology; D002116:Calcitonin / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced; D010148:Intractable Pain / Q000188:drug therapy*; D012004:Rectal Neoplasms / Q000473:pathology / Q000503:physiopathology; D014839:Vomiting / Q000139:chemically induced
D002116:Calcitonin