Effect of temocillin in combination with other beta-lactam antibiotics.
The antibacterial interactions of temocillin with other beta-lactams were tested by checkerboard combination in Mueller-Hinton agar against 146 strains of members of the family Enterobacteriaceae, 35 Pseudomonas aeruginosa strains, and 35 Staphylococcus aureus strains. Most combinations showed a moderate degree of synergism. In only one Klebsiella strain was minor antagonism observed between temocillin and ampicillin.
D000900:Anti-Bacterial Agents / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004338:Drug Combinations; D004357:Drug Synergism; D010406:Penicillins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D010406:Penicillins; D047090:beta-Lactams; C031367:temocillin