[The role of lipid radicals in electron transport and energy transformation].
Data given propose two regimes of lipid radicals and oxygen utilization realized in microsomal and mitochondrial membranes. The first one, lipid peroxidation, i.e. interaction of lipid radicals and oxygen is an empty step. In converting this regime to the functional one NADPH-dependent lipid peroxidation is inhibited. A change of this regime to the functional one in microsome demand the presence of hydroxylation substrates. Setting lipid radical-dependent coupling apparatus on phosphorylation in mitochondria occur in the presence of ADP and Pi-phosphorylation substrates.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000818:Animals; D004579:Electron Transport; D004734:Energy Metabolism; D005609:Free Radicals; D007700:Kinetics; D008054:Lipid Peroxides / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D051381:Rats
D005609:Free Radicals; D008054:Lipid Peroxides; D008315:Malondialdehyde; D000244:Adenosine Diphosphate
Uchastie lipidnykh radikalov v reaktsiiakh s perenosom élektronov i preobrazovaniem énergii.