[In vitro sensitivity of breast cancer tissue to adriablastin in the presence and absence of estrogen receptors].
The report deals with a comparison of estrogen receptor concentration in tumor tissue of breast cancer patients and sensitivity of the said tissue to adriablastin in short-term organ cultures. No relationship was established between tumor tissue sensitivity to adriablastin and presence or absence of estrogen receptors. It is necessary to identify both the concentration of specific hormone receptors and individual sensitivity to chemotherapy in order to work out individually-tailored schemes of treatment of breast cancer patients.
D001943:Breast Neoplasms / Q000032:analysis / Q000188:drug therapy* / Q000378:metabolism; D046508:Culture Techniques; D003600:Cytosol / Q000032:analysis; D004317:Doxorubicin / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D005260:Female; D006801:Humans; D011379:Prognosis; D012334:RNA, Neoplasm / Q000096:biosynthesis; D011960:Receptors, Estrogen / Q000032:analysis*
D012334:RNA, Neoplasm; D011960:Receptors, Estrogen; D004317:Doxorubicin
Chuvstvitel'nost' k adriablastinu opukholevoĭ tkani molochnoĭ zhelezy in vitro pri nalichii i otsutstvii retseptorov éstrogenov.