title: Effect of ABO group, secretor status and sex on cold hemagglutinins in normal adults.
abstract: The ABO group, Lewis type and secretor status were determined in 546 normal individuals (241 male, 305 female). Their serum was tested at 4 degrees C for agglutination of group O red blood cells; the antibody was presumed to be auto-anti-I; the results were expressed as a score. Among non-A female donors, the score was higher for secretors than nonsecretors (p less than 0.05). Among non-A secretors of both sexes, female donors had a higher score than male donors (p less than 0.05). These results suggest that the level of anti-I in the serum of normal individuals may be affected by the donor's ABO group, secretor status and sex.
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics* / Q000276:immunology; D000293:Adolescent; D000328:Adult; D000373:Agglutinins / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D003450:Cryoglobulins; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007048:I Blood-Group System / Q000235:genetics / Q000276:immunology; D007983:Lewis Blood Group Antigens / Q000235:genetics; D008297:Male; D012463:Saliva / Q000276:immunology*; D012727:Sex Characteristics
chemical_list: D000017:ABO Blood-Group System; D000373:Agglutinins; D003450:Cryoglobulins; D007048:I Blood-Group System; D007983:Lewis Blood Group Antigens; C029443:cold agglutinins