title: Does bone measurement on the radius indicate skeletal status? Concise communication.
abstract: Single-photon (I-125) absorptiometry was used to measure bone mineral content (BMC) of the distal third of the radius, and dual-photon absorptiometry (Gd-153) was used to measure total-body bone mineral (TBBM), as well as the BMC of major skeletal regions. Measurements were done in normal females, normal males, osteoporotic females, osteoporotic males, and renal patients. The BMC of the radius predicted TBBM well in normal subjects, but was less satisfactory in the patient groups. The spinal BMC was predicted with even lower accuracy from radius measurement. The error in predicting areal density (bone mass per unit projected skeletal area) of the lumbar and thoracic spine from the radius BMC divided by its width was smaller, but the regressions differed significantly among normals, osteoporotics, and renal patients. There was a preferential spinal osteopenia in the osteoporotic group and in about half of the renal patients. Bone measurements on the radius can indicate overall skeletal status in normal subjects and to a lesser degree in patients, but these radius measurements are inaccurate, even on the average, as an indicator of spinal state.
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000000981:diagnostic imaging; D005260:Female; D005682:Gadolinium; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008722:Methods; D008875:Middle Aged; D008903:Minerals / Q000032:analysis*; D008954:Models, Biological; D010024:Osteoporosis / Q000000981:diagnostic imaging; D011868:Radioisotopes; D011877:Radionuclide Imaging; D011884:Radius / Q000000981:diagnostic imaging*; D012016:Reference Values; D013131:Spine / Q000000981:diagnostic imaging
chemical_list: D007457:Iodine Radioisotopes; D008903:Minerals; D011868:Radioisotopes; D005682:Gadolinium