A Streptococcus mutans immunogen that reacts equally with S. mutans antibody of all serotypes.
We have studied a possible immunogen from S. mutans that has the capability of producing antibody to S. mutans which reacts equally well with all serotypes. This immunogen, a ribosomal preparation, is immunogenic in mice, is antigenic with rabbit anti-S. mutans, and is antigenic with the human antibody that also reacts with S. mutans. The human antibody is of the IgG class and S-IgA class.
D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000276:immunology; D008297:Male; D051379:Mice; D011817:Rabbits; D012270:Ribosomes / Q000276:immunology; D012703:Serotyping; D013295:Streptococcus mutans / Q000145:classification / Q000276:immunology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D007071:Immunoglobulin A, Secretory