Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1.
Blym-1, a transforming gene detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas, was mapped to the short arm of chromosome 1 (1p32) by chromosomal in situ hybridization. The Blym-1 gene was not physically linked to the cellular myc oncogene or to any of the immunoglobulin gene loci implicated in the characteristic chromosomal translocations in Burkitt lymphoma.
D001483:Base Sequence; D002051:Burkitt Lymphoma / Q000235:genetics*; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D008040:Genetic Linkage; D006801:Humans; D007136:Immunoglobulins / Q000235:genetics; D008297:Male; D009693:Nucleic Acid Hybridization; D009857:Oncogenes; D014178:Translocation, Genetic
D007136:Immunoglobulins