title: [Mesothelioma as an index tumor of the occupational hazard of asbestos dust].
abstract: Mesothelioma arises from the cover epithelia of the serous body cavities and is a most malignant and fatal tumour. Since 1978 42 cases of diffusely growing mesothelioma have been observed. An extreme difference in the expected frequency of mesothelioma among previously severely asbestos-dust-exposed persons and the rest of the population is characteristic. Accordingly, death from mesothelioma does not only show a predominantly high occupational asbestos-dust-risk association but also to environmental exposition by neighborhood and household contact. Thus in production and use of asbestos-containing products a risk must be expected. Due to the great likelihood of asbestos-induced mesothelioma in the individual case it is justified to consider this tumour as signal for asbestos exposition decades ago. In the German Federal Republic "pleural and peritoneal mesothelioma caused by asbestos" is a notifiable occupational disease since 1977. Each diagnosis of mesothelioma initiates the suspicion and thus the medical duty of notification of an occupational disease. Following the large increase of asbestos consumption in the GFR over the last 30 years an increase of medically confirmed mesotheliomas can be expected.
mesh_terms: D000328:Adult; D000368:Aged; D001194:Asbestos / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology*; D010534:Peritoneal Neoplasms / Q000209:etiology* / Q000473:pathology; D010997:Pleural Neoplasms / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
chemical_list: D001194:Asbestos
vernacular_title: Das Mesotheliom, ein Signaltumor der beruflichen Asbeststaubgefährdung.