title: Enterococcal endocarditis following sigmoidoscopy and mitral valve prolapse.
abstract: There is considerable controversy regarding antimicrobial prophylaxis against infective endocarditis for routine sigmoidoscopy without biopsy in patients with underlying valvular heart disease. Sigmoidoscopy is known to produce brief, low-grade bacteremia in some patients. Persons with mitral valve prolapse (MVP) may be at risk of infective endocarditis developing during transient bacteremia. We describe a 67-year-old man with known MVP in whom enterococcal endocarditis developed following routine sigmoidoscopy. We believe this to be the first such reported case.
mesh_terms: D000368:Aged; D001769:Blood / Q000382:microbiology; D004562:Electrocardiography; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008945:Mitral Valve Prolapse / Q000150:complications*; D010400:Penicillin G / Q000627:therapeutic use; D012812:Sigmoidoscopy / Q000009:adverse effects*; D013290:Streptococcal Infections / Q000188:drug therapy
chemical_list: D005839:Gentamicins; D010400:Penicillin G