[Effect of carbostimulin on the concentration of tricarboxylic cycle metabolites, oxidative processes and antibody biosynthesis in the rat].
Carbostimulin is studied for the effect it exerts on indices of the acid-base equilibrium of blood, content of certain tricarboxylic-cycle metabolites and free amino acids and formation of antibodies in rats. It is established that carbostimulin feeding increases the total carbon dioxide, pyruvate and lactate concentration in blood, the content of ammonium, glutamine and certain free amino acids being decreased. Oxidation processes in the liver mitochondria and biosynthesis of antibodies in experimental animals are shown to be more intensive than in the control ones.
D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000596:Amino Acids / Q000097:blood*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D002254:Carbonates / Q000494:pharmacology*; D002952:Citric Acid Cycle / Q000187:drug effects*; D004338:Drug Combinations / Q000494:pharmacology; D006019:Glycolysis / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D008278:Magnesium Sulfate / Q000494:pharmacology*; D008297:Male; D008345:Manganese / Q000494:pharmacology*; D017895:Manganese Compounds; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D013745:Tetanus Toxoid / Q000276:immunology; D015032:Zinc / Q000494:pharmacology*; D017967:Zinc Compounds
D000596:Amino Acids; D002254:Carbonates; D004338:Drug Combinations; D017895:Manganese Compounds; D013745:Tetanus Toxoid; D017967:Zinc Compounds; D008345:Manganese; C021160:Carbostimulin; D008278:Magnesium Sulfate; D015032:Zinc
Vliianie karbostimulina na soderzhanie metabolitov trikarbonovogo tsikla, okislitel'nye protsessy i biosintez antitel u krys.