[Determination of fibrin-fibrinogen degradation products in the serum of newborn infants using a standardized hemagglutination inhibition test (the FDP kit)].
By means of the standardised hemagglutination inhibition immunoassay "FDP-Kit" the serum-concentration of fibrin-fibrinogen-split products (FSP) was measured in the cord blood of 36 healthy mature newborns and in the venous blood of 91 mature and immature healthy newborns within the first 5 days of life. The mean values and the values of the upper 95%-confidence limit were calculated. Furthermore determinations were done in the venous blood of 42 diseased newborns (bacterial infections, hyaline membranes, haemorrhage, postpartal shock) was examined. FSP-serum-concentrations higher than 11 micrograms/ml were observed only in ill newborns, concentrations higher than 20 micrograms/ml are reliably pathological values.
D001424:Bacterial Infections / Q000097:blood; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006385:Hemagglutination Inhibition Tests; D006470:Hemorrhage / Q000097:blood; D006801:Humans; D006819:Hyaline Membrane Disease / Q000097:blood; D007231:Infant, Newborn; D007234:Infant, Premature; D012016:Reference Values; D012769:Shock / Q000097:blood
D005338:Fibrin Fibrinogen Degradation Products
Zur Bestimmung der Fibrin-Fibrinogen-Spaltprodukte im Serum von Neugeborenen mit Hilfe eines standardisierten Hämagglutinationshemmtestes (FDP-Kit).