title: An experimental analysis of the interaction of chemotherapy and behavior therapy in anorexia nervosa.
abstract: The interaction of imipramine and operant conditioning on weight gain in an anorexia nervosa patient was examined by a single-subject experiment consisting of a baseline and four treatment phases: phase 1--contingency management only; phase 2--contingency management plus imipramine; phase 3--contingency management plus imipramine placebo; phase 4--contingency management only. The results showed that the interaction of drug and behavior therapy had no significant effect on weight gain, but that imipramine may have contributed to a decrease in depression. Observations are made regarding weight changes related to passes and medication refusals.
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D001521:Behavior Therapy; D001835:Body Weight / Q000187:drug effects; D003131:Combined Modality Therapy; D003216:Conditioning, Operant; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy; D004311:Double-Blind Method; D005260:Female; D006760:Hospitalization; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D008950:MMPI; D010919:Placebos
chemical_list: D010919:Placebos; D007099:Imipramine