Synthetic amino-acid diet prolongs survival in autoimmune murine disease.
The effect of substituting a fully synthetic diet for standard laboratory pellet feed on the course of spontaneous autoimmune disease in New Zealand Black/White hybrid mice was examined. Delays in the development of anti-nuclear antibody, proteinuria and circulating immune complexes were seen; the survival was markedly prolonged. This type of dietary manipulation has a beneficial effect on the course of murine autoimmune disease.
D000596:Amino Acids / Q000008:administration & dosage* / Q000494:pharmacology; D000818:Animals; D001327:Autoimmune Diseases / Q000150:complications / Q000178:diet therapy* / Q000401:mortality; D003433:Crosses, Genetic; D005526:Food, Formulated; D005921:Glomerulonephritis / Q000209:etiology; D051379:Mice; D008814:Mice, Inbred NZB
D000596:Amino Acids