Transdermal scopolamine in the treatment of acute vertigo.
A double-blind, parallel investigation was undertaken to evaluate the efficacy of transdermally delivered scopolamine hydrobromide in acute vertigo as compared to meclizine hydrochloride and placebo. Statistical analysis of subjective patient responses and clinical observations suggested that both scopolamine and meclizine are more effective than placebo. Both have significant, but different, side effects.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007271:Injections, Intradermal; D008297:Male; D008468:Meclizine / Q000008:administration & dosage; D008575:Meniere Disease / Q000188:drug therapy; D008875:Middle Aged; D012601:Scopolamine / Q000008:administration & dosage*; D014717:Vertigo / Q000188:drug therapy*
D008468:Meclizine; D012601:Scopolamine