title: [Principles of NASA longitudinal medical studies].
abstract: This paper describes approaches to longitudinal studies of the changes in the health status of the US astronauts. The methods include acquisition and analysis of biomedical data accumulated in one and repeated space missions, detection of potential occupational diseases inflight and evaluation of mortality cases associated with them. It is suggested to use pilots and flight controllers as controls. It is indicated that annual physical examinations can be an important source of relevant scientific information.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001835:Body Weight; D005260:Female; D006077:Government Agencies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology / Q000209:etiology; D012106:Research; D012306:Risk; D013026:Space Flight / Q000295:instrumentation; D013997:Time Factors; D014481:United States
vernacular_title: Printsipy perspektivnykh meditsinskikh issledovaniĭ NASA.