Seizures and pregnancy.
Managing epilepsy during pregnancy requires frequent monitoring of medication, avoidance of fatigue, and strict compliance with appropriate medications. While epileptic mothers as a group have approximately twice the usual rate of fetal malformations, only trimethadione has been proved to be teratogenic in humans. Thus, maintaining effective serum levels of the usual anticonvulsants is the safest way to manage the epileptic mother and the fetus.
D000014:Abnormalities, Drug-Induced; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced; D006801:Humans; D006827:Hydantoins / Q000009:adverse effects; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000503:physiopathology*; D014293:Trimethadione / Q000009:adverse effects
D000927:Anticonvulsants; D006827:Hydantoins; D014293:Trimethadione