Glomerular deposition of Hageman factor in IgA nephropathy.
Glomerular localization of Hageman factor and fibrin-related antigen (FRA) was examined in 31 cases of IgA nephropathy by immunofluorescent techniques. Hageman factor was observed in 21 cases (68%) and FRA in 24 cases (77%). It is suggested that blood coagulation occurs and fibrin is formed in the glomerulus of IgA nephropathy.
D000941:Antigens / Q000032:analysis; D005174:Factor XII / Q000032:analysis*; D005337:Fibrin / Q000032:analysis*; D005921:Glomerulonephritis / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007678:Kidney Glomerulus / Q000276:immunology*
D000941:Antigens; D007070:Immunoglobulin A; D005174:Factor XII; D005337:Fibrin