title: [Role of the bursa of Fabricius in regulating the hemostatic system in the chicken].
abstract: Bursa Fabricii was removed in 35-40-day old chicken. Experiments were then performed in adult bursectomized and placebo--operated chicken in 1.5 months after the operation. The bursectomized chicken developed hypercoagulation, an increased concentration of fibrinogen and inhibition of euglobulin fibrinolysis. Their responses of the blood coagulation and fibrinolysis systems to administration of adrenalin and heterogeneous (human) blood were inadequate. The findings suggest an important role of bursa Fanricii, which is an immunologically competent organ, in regulation of hemostasis.
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D002060:Bursa of Fabricius / Q000502:physiology*; D002645:Chickens / Q000097:blood*; D004837:Epinephrine / Q000494:pharmacology; D005342:Fibrinolysis / Q000187:drug effects; D012621:Seasons; D012769:Shock / Q000097:blood; D065227:Transfusion Reaction
chemical_list: D004837:Epinephrine
vernacular_title: O roli sumki Fabritsiusa v reguliatsii sistemy gemostaza u kur.