[The macrophage adherence inhibition test in Wistar rats bearing Jensen tumors. II. Macrophage adherence inhibition test after intravenous administration of spores of the CNRZ 528 strain of Clostridium butyricum and incubation with clostridial antigens].
The tumor-specificity of tumor-clostridia-phenomenon in the model of Jensen-sarcoma of the white rat was detected with the help of humoral and cell-mediated immune reactions of the host towards intravenous application of 5 X 10(8) spores of clostridia, which do not dissolve the tumor. Contrary to weak responses in Widal-agglutination the MAI showed characteristic values of inhibition of peritoneal-cell-adherence in tumor-bearing animals after incubation with soluble clostridia antigens.
D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000276:immunology*; D002448:Cell Adhesion; D003013:Clostridium / Q000276:immunology*; D005260:Female; D007111:Immunity, Cellular; D008264:Macrophages / Q000276:immunology*; D051381:Rats; D011919:Rats, Inbred Strains; D012513:Sarcoma, Experimental / Q000276:immunology*; D013170:Spores / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Der Makrophagen-Adhärenz-Hemmtest (MAI) bei Jensen-Tnmor tragenden Wistar-Ratten. II. MAI nach intravenöser Applikation von Sporen des Stammes Clostridium butyricum CNRZ 528 und Inkubation mit Clostridienantigenen.