title: [Antenatal oogenesis in mice and its experimental modification].
abstract: The repeated (twice) intramuscular injection of oxytetracycline (5 mg per mouse) within 12 and 13 days after mating induced the increase of a relative number of pathological and atretic mitoses in the oogonia and, later on, the decrease of a relative number of diplotenes and early dictyotenes. The same dose injected within 16 and 17 days induced a higher degeneration of oocytes in pachytene and diplotene and inhibited the initiation of folliculogenesis.
mesh_terms: D000818:Animals; D005260:Female; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D009865:Oocytes / Q000187:drug effects; D009866:Oogenesis / Q000187:drug effects; D009867:Oogonia / Q000187:drug effects; D010053:Ovary / Q000187:drug effects / Q000196:embryology; D010118:Oxytetracycline / Q000494:pharmacology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013997:Time Factors
chemical_list: D010118:Oxytetracycline
vernacular_title: Antenatal'nyĭ oogenez u mysheĭ i ego éksperimental'naia modifikatsiia.