title: Statistical significance of molecule projections by single particle averaging.
abstract: A statistical test based on a multiple comparison of Friedman's rank sums has been developed to determine the statistical significance of molecule projections obtained by non-crystallographic averaging techniques. The test, applied to electron microscope images of the acetylcholine receptor molecule, confirms the significance and quoted resolution of averages by Zingsheim et al. (1980, 1982a, b).
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D046911:Macromolecular Substances; D055095:Optics and Photonics; D011950:Receptors, Cholinergic; D013223:Statistics as Topic
chemical_list: D046911:Macromolecular Substances; D011950:Receptors, Cholinergic