[Reaction products of indandione with ethyl alpha-cyano-beta-acrylates].
In order to obtain biologically active compounds with a probable anticoagulant activity, some new products, by Michael method from indandione and 2-phenylindandione with ethyl alpha-cyano-beta-aryl-acrylates, have been prepared. The reaction of phenylindandione with methylvinylketone has been also carried out. The products have been characterized by chemical analysis and spectral determinations. The products showed an anticoagulant activity "in vitro" in a preliminary pharmacological screening.
D000925:Anticoagulants / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D003487:Cyanoacrylates / Q000378:metabolism*; D007189:Indans / Q000378:metabolism*; D007192:Indenes / Q000378:metabolism*
D000925:Anticoagulants; D003487:Cyanoacrylates; D007189:Indans; D007192:Indenes; C029054:ethyl 2-cyanoacrylate; C001445:1,3-indandione
Prodotti di reazione dell'indandione con alpha-ciano-beta-arilacrilati di etile.