Dominant inheritance of bifid nose.
To our knowledge, median cleft of nose without apparent hypertelorism (bifid nose) has been reported only twice [Esser, 1939; Boo-chai, 1965]. We report five individuals in 3 generations of a family who had a bifid nose without apparent hypertelorism or mental retardation. In this family bifid nose was most likely an autosomal dominant trait.
D000015:Abnormalities, Multiple / Q000235:genetics; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003103:Coloboma / Q000235:genetics; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008831:Microcephaly / Q000235:genetics; D009666:Nose / Q000002:abnormalities*; D010375:Pedigree; D012160:Retina / Q000002:abnormalities