title: Assessment of lung water content by roentgen videodensitometry.
abstract: In 17 anesthetized and mechanically ventilated pigs, different degrees of lung injury were induced by iv infusion of oleic acid (mean dose 0.1 ml/kg). The change in radiologic density of the chest was measured by a videodensitometer before and 4 h after oleic acid infusion. The lungs were then removed for determination of the wet/dry weight ratio (WW/DW). The change in radiologic density was significantly correlated to WW/DW (r = .87) and to the changes in end-inspiratory pressure (r = .80), mean pulmonary arterial pressure (r = .77) and venous admixture (r = .79), but not to changes in the oncotic-hydrostatic pressure gradient of the lungs (r = .46). Roentgen videodensitometry appears to be a useful method for assessing changes in extravascular lung water content.
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000818:Animals; D001834:Body Water / Q000032:analysis*; D008168:Lung / Q000032:analysis / Q000000981:diagnostic imaging*; D013552:Swine; D014741:Video Recording