title: Search for a nontoxic surgical scrub solution for periorbital lacerations.
abstract: The purpose of this study was to identify a skin wound cleanser that could be used safely to cleanse lacerations of the periorbital region. The irritation and toxicity to the eye of the commercially available skin wound cleansers were quantitated using numerical values and weights for the ocular lesions in experimental animals. Shur Clens did not elicit lesions in experimental animals or in a series of 20 patients with periorbital lacerations. On the basis of this study, Shur Clens is recommended as a safe skin wound cleanser for periorbital lacerations.
mesh_terms: D000818:Animals; D003902:Detergents / Q000633:toxicity*; D004341:Drug Evaluation; D005131:Eye Injuries / Q000139:chemically induced* / Q000517:prevention & control; D005151:Facial Injuries / Q000628:therapy; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D011817:Rabbits; D013501:Surface-Active Agents / Q000633:toxicity*
chemical_list: D003902:Detergents; D013501:Surface-Active Agents