[Cervical dysplasia].
General characteristics of nucleoli in all layers of stratified squamous epithelium were studied in 234 cases of dysplasia and intraepithelial cancer of cervix uteri. Cytomorphometric measurements were carried out. The nuclear-cytoplasmic ratio was determined. Certain regularities pertinent to neoplastic process progression and aging were established. 2,375 patients with moderate dysplasia and 1,625 patients with marked dysplasia underwent clinical examination. Various schemes of treatment and long-term results were evaluated. Rationale for all-round examination and individually-tailored schemes of treatment is discussed. The data on the end results in 150 untreated cases of dysplasia are presented. The importance of detection and treatment of dysplasia in the control of cervical cancer is suggested.
D000328:Adult; D000367:Age Factors; D000368:Aged; D002278:Carcinoma in Situ / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002466:Cell Nucleolus / Q000648:ultrastructure; D004564:Electrocoagulation; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007844:Latvia; D008403:Mass Screening; D008875:Middle Aged; D012189:Retrospective Studies; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery
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