Prolactin mRNA exists in rat hypothalamus.
Using radiolabeled DNA complementary to rat pituitary prolactin mRNA, we probed RNA gel blots from three rat tissues: pituitary, hypothalamus, and liver. Poly (A)-enriched RNA from male and female hypothalami contained a hybridizable RNA which was the same size as, though less abundant than, mature pituitary PRL mRNA. These results support the proposal that the rat brain synthesizes PRL.
D000818:Animals; D005260:Female; D007031:Hypothalamus / Q000032:analysis*; D008297:Male; D009693:Nucleic Acid Hybridization; D011388:Prolactin / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D012333:RNA, Messenger; D011388:Prolactin