Metabolism of orally administered alkyl beta-glycosides in the mouse.
The metabolism of octyl beta-D-[U-14C]glucoside, ]1-14C]dodecyl beta-D-maltoside and [1-14C]hexadecyl beta-D-glucoside was studied after oral administration to mice. The beta-glycosidic bond was rapidly hydrolyzed in intestine and liver. The cleavage products, sugars and long-chain alcohols, entered the pathways of lipid and carbohydrate metabolism. It appears that alkyl beta-glycosides are suitable as additives in food and feed.
D000818:Animals; D005260:Female; D005503:Food Additives / Q000378:metabolism / Q000633:toxicity; D005960:Glucosides / Q000378:metabolism* / Q000633:toxicity; D006027:Glycosides / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D051379:Mice; D012995:Solubility; D014018:Tissue Distribution
D005503:Food Additives; D005960:Glucosides; D006027:Glycosides; C018619:octyl-beta-D-glucoside; C040358:dodecyl maltoside; C040357:hexadecyl glucoside