Phagocyte-induced mutation in Chinese hamster ovary cells.
Human phagocytic cells elaborate toxic oxygen metabolites which can cause mutations in bacteria and sister chromatid exchanges in cultured mammalian cells. In the present study we demonstrate that human phagocytes can induce mutations in Chinese hamster ovary cells.
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D008722:Methods; D009154:Mutation; D010053:Ovary; D010586:Phagocytes / Q000502:physiology*; D012854:Sister Chromatid Exchange
D007041:Hypoxanthine Phosphoribosyltransferase