Changes in the tissue lipid profiles of fish (Oreochromis mossambicus) during methyl parathion toxicity--a time course study.
The levels of total lipids, phospholipids, free fatty acids and total cholesterol were studied in selected tissues of the fish, Oreochromis mossambicus under sublethal stress of methyl parathion for 48 h. The levels of total lipids and phospholipids decreased while the free fatty acids and total cholesterol levels increased during the exposure period. These results are discussed in relation to induced gluconeogenesis and the diversion of acetyl CoA to cholesterol synthesis during methyl parathion intoxication.
D000818:Animals; D001921:Brain / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D005880:Gills / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008743:Methyl Parathion / Q000633:toxicity*; D009132:Muscles / Q000378:metabolism; D010278:Parathion / Q000031:analogs & derivatives*; D010743:Phospholipids / Q000378:metabolism; D013997:Time Factors
D005230:Fatty Acids, Nonesterified; D010743:Phospholipids; D008743:Methyl Parathion; D010278:Parathion; D002784:Cholesterol