Intradermal immunization with human diploid cell rabies vaccine: serological and clinical responses of immunized persons to intradermal booster vaccination.
Rabies antibody titers ranged from 0-9.3 IU/mL in 117 human volunteers one year after intradermal vaccination with one or two doses of human diploid cell rabies vaccine (HDCV). At that time, each volunteer received one 0.1-mL booster dose of HDCV intradermally. All 117 volunteers showed good anamnestic responses, with antibody titers rising to 0.5-54.3 IU/mL within seven days of booster injection. Vaccine safety was good; only minor reactions were experienced, all of which resolved spontaneously.
D004334:Drug Administration Schedule; D005069:Evaluation Studies as Topic; D006801:Humans; D007117:Immunization, Secondary; D007271:Injections, Intradermal; D011818:Rabies / Q000276:immunology*; D011819:Rabies Vaccines / Q000008:administration & dosage*; D011795:Surveys and Questionnaires
D011819:Rabies Vaccines