Comparison of blood levels of histamine and total ascorbic acid in pre-eclampsia with normal pregnancy.
Levels of histamine and total ascorbic acid (L-ascorbic acid plus dehydroascorbic acid) in the peripheral blood of women in pre-eclampsia have been measured. The results show that blood histamine is increased both in the moderate and severe form of pre-eclampsia. Blood ascorbic acid on the other hand is increased only in the severe form of pre-eclampsia. The rise in histamine values may be in response to the rising blood pressure in pre-eclampsia. The rise in ascorbic acid values may reflect the reduced maternal blood volume and/or restricted transport of ascorbic acid from maternal to fetal tissues.
D000328:Adult; D001205:Ascorbic Acid / Q000097:blood*; D001692:Biological Transport; D001794:Blood Pressure; D005260:Female; D005865:Gestational Age; D006632:Histamine / Q000097:blood*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy
D006632:Histamine; D001205:Ascorbic Acid