Differential enzyme activities in human esterase D phenotypes.
Red cell ESD activities have been determined in 78 individuals with ESD-1 phenotype, in 94 with ESD2-1 and in 28 with ESD-2 phenotype. The mean activities of these three groups were 276.7, 216.6 and 171.5 expressed as 10(-7) M methylumbelliferone produced/h/g Hb, respectively. The activities associated with a single ESD*1 gene are estimated to be 60% higher than ESD*2.
D000483:Alleles; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000097:blood / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic
D007527:Isoenzymes; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; C020118:ESD protein, human