The type of anastomosis after selective gastric vagotomy and precise antrectomy is of no importance for basal and postprandial serum gastrin concentration.
Twenty-six patients were treated for duodenal or recurrent ulcer with selective gastric vagotomy plus precise antrectomy--that is, complete removal of the entire antrum. Sixteen had a gastroduodenal anastomosis and 10 a gastrojejunal anastomosis. Fasting and protein meal-stimulated serum gastrin concentration was measured in 10 patients before antrectomy and in all after the operation. Fasting serum gastrin concentration was reduced and food-stimulated gastrin response abolished irrespective of the type of the anastomosis. It is concluded that a postprandial gastrin rise means retained antral tissue in the gastric remnant and that neither protein nor mechanical stimulation of the passage of food through the duodenum stimulates the duodenal G-cells to gastrin release.
D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000601:surgery*; D004386:Duodenum / Q000601:surgery; D005215:Fasting; D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011706:Pyloric Antrum / Q000601:surgery*; D012008:Recurrence; D014628:Vagotomy; D014629:Vagotomy, Proximal Gastric
D005755:Gastrins