title: Effects of hypophysectomy on some osmoregulatory parameters of the catfish, Heteropneustes fossilis (Bloch).
abstract: The catfish, H. fossilis, survives for long periods after hypophysectomy, although with impaired osmoregulatory mechanisms. Plasma osmolarity and cortisol levels decline significantly within 2 hr after hypophysectomy and attain the lowest values by about 27 hr. Hypophysectomy also results in a marked decrease in urine flow rate principally due to reduced glomerular filtration. The reduction in the ability of the kidney of hypophysectomized catfish to eliminate water results in hyperhydration of blood and muscle. Urine osmolarity and sodium concentration increase due to reduced tubular reabsorption of sodium. There is, however, no net change in the total urinary sodium loss. The catfish survives in fresh water after hypophysectomy presumably because its tissues can tolerate significant dilution of the body fluids.
mesh_terms: D000818:Animals; D005399:Fishes / Q000502:physiology*; D006854:Hydrocortisone / Q000097:blood; D007016:Hypophysectomy; D007668:Kidney / Q000502:physiology; D009994:Osmolar Concentration; D012964:Sodium / Q000652:urine; D014882:Water-Electrolyte Balance
chemical_list: D012964:Sodium; D006854:Hydrocortisone