Two hemoglobin-binding proteins identified in the plasma of the amphibian Taricha granulosa.
The plasma of the amphibian newt Taricha granulosa has been shown to be devoid of haptoglobin. Upon hemolysis, Taricha albumin and another protein associate with hemoglobin. The acute-phase response to inflammation observed in birds and mammals appears to be absent in Taricha. Taricha hemoglobin failed to bind to human haptoglobin. Taricha hemoglobin not only failed to dissociate into alpha beta dimers as did human Hb, but formed alpha beta octamers.
D000818:Animals; D001426:Bacterial Proteins; D002352:Carrier Proteins / Q000097:blood*; D006242:Haptoglobins / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008970:Molecular Weight; D011487:Protein Conformation; D012455:Salamandridae / Q000097:blood*; D012709:Serum Albumin / Q000378:metabolism
D001426:Bacterial Proteins; D002352:Carrier Proteins; D006242:Haptoglobins; D006454:Hemoglobins; D012709:Serum Albumin; C017206:hemoglobin-binding protein, bacteria