title: [Results of the surgical treatment of pancreatic cancer. Study of a series of 96 surgically treated patients].
abstract: From 1970 to 1980, 96 patients were operated on for pancreatic adenocarcinoma. Histological confirmation was obtained in all but 12 cases. The tumour was located in the right portion of the pancreas in 80 cases and in the left portion in 16 cases. Metastases were present in 39 patients, hepatic in 28 cases and peritoneal in 23 cases. Among the cases without metastasis, lymph node involvement was found in 12 patients out of 25. A partial pancreatectomy was carried out in 12 patients, by-pass operations in 50 patients and laparotomy only in 34 patients. The 30-day postoperative mortality rate was 12 p. 100 in the by-pass group; there was no postoperative death in the resected group. By 1982, all the patients were dead. The mean length of survival after Whipple resection was 15.6 months, after by-pass operations 8 months, after laparotomy 3.4 months, operative mortality excluded. When lymph nodes were involved (stage III), the mean duration of survival after resection (n = 4) was the same (i.e. 7,5 months) as that after by-pass operations. The period of survival after by-pass procedures only exceeded one year in 8 cases. After pancreatic resection, only one patient survived five years. These results show that the resectability rate of pancreatic carcinoma is very low. Pancreatic resection seems to be justified mainly in stage I and II tumors. However, prognosis of pancreatic carcinoma remains very poor and the 5-year survival rate after resection does not exceed 10 p. 100.
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000401:mortality; D010190:Pancreatic Neoplasms / Q000601:surgery*; D010534:Peritoneal Neoplasms / Q000556:secondary; D013997:Time Factors
vernacular_title: Les résultats du traitement chirurgical du cancer du pancréas. Etude d'une série de 96 opérés.