Aortic insufficiency following mediastinal radiation for Hodgkin's disease.
Aortic insufficiency developed 13 months after mediastinal radiation in a patient with Hodgkin's disease. The estimated cardiac dose was 4200 rads. Several years later, a cerebral embolus occurred. The evidence for valvular and endocardial damage due to radiation is reviewed.
D000328:Adult; D001022:Aortic Valve Insufficiency / Q000209:etiology*; D006321:Heart / Q000528:radiation effects*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries