title: Amputation stumps studied by bone scanning. Work in progress.
abstract: Nine diabetic and 7 nondiabetic (post-trauma) patients 24 to 63 years of age (mean, 49) were scanned following amputation below the knee, which was bilateral in 4. A three-phase scanning technique (flow, blood pool, and delayed equilibrium images) was employed, using Tc-99m-etidronate. Duration of the arterial and capillary phases was estimated during flow. Activity at the tip of the stump was plotted as a function of (a) time since amputation and (b) flow measurements. Activity was found to diminish over a period of nearly 50 months, usually becoming minimal or undetectable after 18 months. The stump demonstrated relative stasis compared to the intact limb, particularly in diabetics and patients with long-standing amputation.
mesh_terms: D000328:Adult; D000672:Amputation Stumps; D001842:Bone and Bones / Q000000981:diagnostic imaging; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000503:physiopathology; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000601:surgery; D008875:Middle Aged; D011877:Radionuclide Imaging; D012039:Regional Blood Flow