[Experimental intravascular pressure-volume measurement for assessment of the biomechanical load tolerance of microvascular anastomoses].
To investigate the tolerance of microvascular anastomoses to a mechanical load, we performed experimental intravascular pressure-volume measurements on the abdominal aorta and the renal vein in the rat. In one group the vessels were sectioned and repaired with interrupted sutures, while in the control group no surgical intervention was performed. The pressure studies were all undertaken on the 14th post-operative day. All operated vessels showed a distinct decrease in elasticity. High intravascular pressure was reached with little injection volume, but there was no difference between the two groups with respect to the pressure at which leakage occurred. Leaks were located between the single sutures. In no case was a complete disruption observed at the anastomotic site. Consequently, the strength of microvascular anastomoses depends mostly on the suture material. In the experiments the suture material, the number of interrupted sutures and their thickness did not differ from those used in clinical application. This suggests that on the 14th postoperative day microvascular anastomoses on human vessels are of the same strength as demonstrated by our experimental anastomoses. In our opinion therefore reoperation at the anastomotic site or well controlled physical therapy can be tolerated in the clinical case without any risk of anastomotic disruption at least by the 14th postoperative day.
D000818:Animals; D001012:Aorta, Abdominal / Q000502:physiology / Q000601:surgery*; D001166:Arteriovenous Shunt, Surgical; D001794:Blood Pressure; D001810:Blood Volume; D008297:Male; D008866:Microsurgery; D051381:Rats; D011919:Rats, Inbred Strains; D012082:Renal Veins / Q000502:physiology / Q000601:surgery*; D014655:Vascular Resistance
Experimentelle intravasale Druck-Volumen-Messung zur Beurteilung der biomechanischen Belastbarkeit mikrovaskulärer Anastomosen.