Blood findings in lymphogranulomatosis X.
A quantitative analysis of leukocytes in the peripheral blood of 16 patients with lymphogranulomatosis X revealed the following findings: The number of total leukocytes, monocytes, neutrophils, and eosinophils varied considerably and showed no clear common tendency. Blood basophils were found to be clearly increased with a mean value of 0.17 +/- 0.18 X 10(9)/1 as compared to 55 normal donors (0.04 +/- 0.01 X 10(9)/1). Lymphocyte counts were within the normal range. Lymphopenia was seen in 2 patients. Lymphocytes with azure granules which encompass T-suppressors were found to exceed normal values by a factor of 15. In 14 cases a variable number of hyperbasophil cells were present. Lymphogranulomatosis X seems to present with a characteristic blood picture which might be of diagnostic aid.
D000328:Adult; D001491:Basophils; D004804:Eosinophils; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000097:blood* / Q000276:immunology / Q000473:pathology; D007958:Leukocyte Count; D008214:Lymphocytes; D008231:Lymphopenia / Q000503:physiopathology; D009504:Neutrophils