Acquired pulmonary stenosis due to pleomorphic adenocarcinoma.
Acquired pulmonary stenosis was diagnosed in a 53 year old woman presenting with the unusual feature of an oral murmur. Mediastinotomy showed extensive malignant tissue surrounding the pulmonary artery, although a mediastinal mass was not evident on chest radiographs. Histological examination confirmed a pleomorphic adenocarcinoma, which has not previously been reported as causing acquired pulmonary stenosis.
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D011666:Pulmonary Valve Stenosis / Q000209:etiology*