title: [Evolution of the treatment of tuberculosis].
abstract: An evolution analysis of tuberculosis management includes four essential times. The first time coincides with the streptomycin therapeutic employment; the second develops with isoniazid disposing; the third time takes in the period of identification of several drugs a long time called "minor", but very important to formulate some "ad personam" therapeutic patterns. At last, the fourth time is characterized by formulation of short-course chemotherapy. Now the suggested protocol is a regimen of short-course chemotherapy with daily administration of INH and RIF for six-nine months with an initial supplement of ethambutol, or streptomycin or pyrazinamide for the first two months.
mesh_terms: D000553:Ambulatory Care; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D006760:Hospitalization; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D010349:Patient Compliance; D012293:Rifampin / Q000627:therapeutic use; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000635:transmission
chemical_list: D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin
vernacular_title: Evoluzione del trattamento della tubercolosi.