A comparative trial testing budesonide and flunisolide nasal sprays in patients with seasonal allergic rhinitis.
A group comparative study was carried out in 60 patients suffering from seasonal allergic rhinitis in order to evaluate the effects and side effects of the recently introduced glucocorticoids budesonide and flunisolide delivered as nasal sprays. Symptom scores for nasal and ocular symptoms as well as pollen counts were registered daily for one month. Both treatments provided excellent control of nasal symptoms. However, a significantly higher number of patients in the flunisolide group complained about nasal irritation.
D000293:Adolescent; D000328:Adult; D000336:Aerosols; D019819:Budesonide; D004844:Epistaxis / Q000139:chemically induced; D005260:Female; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011282:Pregnenediones / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D011897:Random Allocation; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*
D000336:Aerosols; D011282:Pregnenediones; D005446:Fluocinolone Acetonide; D019819:Budesonide; C007734:flunisolide