title: Successful treatment of leptomeningeal relapse of epithelial ovarian cancer.
abstract: A case of isolated leptomeningeal recurrence of an epithelial ovarian cancer was recently diagnosed and treated successfully with methotrexate placed via an Ommaya reservoir in combination with radiation therapy. A review of the literature revealed no other cases of epithelial ovarian leptomeningeal malignancy similarly treated.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004343:Drug Implants; D005260:Female; D006801:Humans; D007813:Laparotomy; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology*; D011878:Radiotherapy
chemical_list: D004343:Drug Implants; D008727:Methotrexate