Spinal cord injury associated with hyperthermia during aortic coarctation repair.
Three infants with coarctation of the thoracic aorta, patent ductus arteriosus (PDA), and ventricular septal defect (VSD) underwent repair of the coarctation in three different institutions. Despite a technically uncomplicated operation, each was noted to have significant paraplegia postoperatively. Retrospective analysis revealed that each patient had been hyperthermic during the time of aortic cross-clamping. It is possible that the hyperthermia, either alone or in combination with other factors, contributed to the development of paraplegia in these three infants.
D001017:Aortic Coarctation / Q000601:surgery*; D006328:Cardiac Catheterization; D002675:Child, Preschool; D003250:Constriction / Q000009:adverse effects; D004374:Ductus Arteriosus, Patent / Q000150:complications; D005260:Female; D005334:Fever / Q000150:complications*; D006333:Heart Failure / Q000150:complications; D006345:Heart Septal Defects, Ventricular / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male; D010264:Paraplegia / Q000209:etiology*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013116:Spinal Cord / Q000503:physiopathology*