title: Pulmonary uptake in indium-111 leukocyte imaging: clinical significance in patients with suspected occult infections.
abstract: A retrospective review was undertaken to evaluate the frequency and significance of pulmonary activity noted on 306 indium-111 leukocyte studies involving 232 patients with suspected occult infections. Forty-eight studies showed pulmonary activity in one of two patterns of uptake, focal or diffuse. Fourteen of 27 studies (52%) with focal uptake and two of 21 studies (10%) with diffuse uptake were associated with infectious processes. Lung uptake of indium-111-labeled leukocytes was a poor predictor of pulmonary infection in patients studied for occult infection, although the focal pattern was more likely than the diffuse pattern to be associated with infection.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004653:Empyema / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007204:Indium; D007962:Leukocytes; D008168:Lung / Q000000981:diagnostic imaging; D008169:Lung Abscess / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000000981:diagnostic imaging*; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012189:Retrospective Studies
chemical_list: D011868:Radioisotopes; D007204:Indium