title: Phosphatidylethanol formation in rat organs after ethanol treatment.
abstract: An abnormal acidic phospholipid was found in high concentration in kidney and brain, and also in other organs of rats exposed to ethanol by i.p. injection or by a liquid diet. The compound could be identified as phosphatidylethanol. Phosphatidylethanol is probably formed in cell membranes by a phospholipase D-catalyzed transphosphatidylation reaction.
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010743:Phospholipids / Q000096:biosynthesis* / Q000378:metabolism*; D051381:Rats; D014018:Tissue Distribution
chemical_list: D010743:Phospholipids; D000431:Ethanol