The binding of triethyllead to rat and cat hemoglobin.
Equilibrium dialysis experiments were carried out to determine the affinity constant and stoichiometry of the binding of triethyllead to rat and cat hemoglobin. The affinity constants were 4 X 10(5) M-1 and 4.5 X 10(5) M-1 for rat and cat hemoglobin, respectively, and 2 mol triethyllead combined with 1 mol hemoglobin. The previous report of a stoichiometry of 3 could not be confirmed (Byington et al., 1980).
D000818:Animals; D001665:Binding Sites; D002415:Cats; D003956:Dialysis; D006454:Hemoglobins / Q000378:metabolism*; D007854:Lead / Q000097:blood*; D009942:Organometallic Compounds / Q000097:blood*; D011485:Protein Binding; D051381:Rats
D006454:Hemoglobins; D009942:Organometallic Compounds; D007854:Lead; C010360:triethyllead