Identification of an infective stage of Leishmania promastigotes.
Sequential development of Leishmania promastigotes from a noninfective to an infective stage was demonstrated for promastigotes growing in culture and in the sandfly vector. The generation of an infective stage was found to be growth cycle-dependent and restricted to nondividing organisms.
D000818:Animals; D002478:Cells, Cultured; D007303:Insect Vectors / Q000469:parasitology; D007891:Leishmania / Q000254:growth & development / Q000502:physiology*; D007896:Leishmaniasis / Q000469:parasitology / Q000635:transmission; D008264:Macrophages / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D011576:Psychodidae / Q000469:parasitology