[Membranoproliferative glomerulonephritis as an unusual initial manifestation in a case of plasmacytoma].
The Authors describe a case of membranoproliferative glomerulonephritis associated with nephrotic syndrome in a 50-year-old man with plasmocytoma. The bone marrow and the immunoelectrophoresis of the serum and urine showed a Bence-Jones positive multiple myeloma with plasma cells secreting only k light chain. The patient responded immediately to monthly courses of cyclophosphamide, melphalan, vincristine and prednisone. He showed still, 27 months after the diagnosis, complete remission of the disease.
D001536:Bence Jones Protein / Q000652:urine; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010954:Plasmacytoma / Q000150:complications*; D011658:Pulmonary Fibrosis / Q000209:etiology
D001536:Bence Jones Protein; D007213:Indomethacin
Glomerulonefrite membranoproliferativa quale insolita manifestazione d'esordio in un caso di plasmocitoma.