title: Malignant melanoma brain metastases. Review of Roswell Park Memorial Institute experience.
abstract: One-hundred twenty five of 700 patients with malignant melanoma treated at Roswell Park Memorial Institute from 1972 to 1978 were found to have brain metastases. Seventy-three percent of the patients had multiple brain metastases. Male to female ratio was 1.9:1. The median survival of the untreated group of patients was 3 weeks as compared with that of 6 weeks for the patients maintained on steroids only, 9 weeks for those who received radiotherapy, 11 weeks for the patients treated with intraarterial chemotherapy, and 26 weeks for the patients who underwent successful surgical excision of a solitary lesion.
mesh_terms: D001344:Autopsy; D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000556:secondary* / Q000628:therapy; D012189:Retrospective Studies; D012737:Sex Factors