title: A model for adhesion formation by thermal injury in the abdominal cavity of the mouse.
abstract: An experimental model for inducing peritoneal adhesions in mice is described. Measurable thermal trauma can be inflicted by the application of a heated metal object, for a given lapse of time, to the surface of a section of mouse intestine. Parameters of temperature, area and application time were so manipulated as to obtain adhesions in only 70-75% of treated mice. It is maintained that this model can enable better evaluation of various prophylactic means and also the detection of exacerbating agents.
mesh_terms: D000818:Animals; D002056:Burns / Q000150:complications / Q000662:veterinary*; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D051379:Mice; D010532:Peritoneal Diseases / Q000209:etiology / Q000662:veterinary*; D012376:Rodent Diseases / Q000209:etiology*; D013997:Time Factors; D000267:Tissue Adhesions / Q000209:etiology / Q000662:veterinary*