title: The effect of impulse noise on cochlear vessels.
abstract: Short- and long-term changes in the cochlear vasculature and long-term changes in the sensorineuroepithelium were studied in guinea pigs after they were exposed to impulse noise. Vessel histology and cochlear hair cell loss were assessed, using a surface-preparation technique, and the results showed considerable variability. Hair cell loss and radial tears in the organ of Corti were a common finding in the animals killed four weeks after impulse-noise exposure. Impulse-noise exposure resulted in few cochlear vascular changes in the acutely and chronically affected groups. Compared with the results of our previous studies using continuous-noise exposure of different characteristics and in different mammals, this impulse-noise experiment resulted in a nonsignificant damaging effect on the cochlear vasculature.
mesh_terms: D000818:Animals; D003051:Cochlea / Q000098:blood supply*; D005260:Female; D006168:Guinea Pigs; D006198:Hair Cells, Auditory; D006199:Hair Cells, Auditory, Inner; D006317:Hearing Loss, Noise-Induced / Q000473:pathology; D006319:Hearing Loss, Sensorineural / Q000473:pathology; D009622:Noise / Q000009:adverse effects*; D009925:Organ of Corti