title: Molded tympanic heterografts. Histologic evaluation.
abstract: The histologic appearance of the molded tympanic heterograft developed at the ENT Clinic of the University of Parma, Italy, is investigated with light and electron microscopy. Evaluation of the graft before insertion disclosed a unique structure of interwoven collagen bundles. Examination of grafted tympanic membrane showed a structure closely resembling the normal human tympanic membrane. The fate of the heterologous material and the host reaction to it are discussed in relation to histologic findings.
mesh_terms: D001705:Bioprosthesis; D003094:Collagen; D005069:Evaluation Studies as Topic; D006801:Humans; D009225:Myringoplasty; D011474:Prosthesis Design; D014432:Tympanic Membrane / Q000033:anatomy & histology* / Q000648:ultrastructure; D014433:Tympanoplasty
chemical_list: D003094:Collagen