Proposed standardization of methods for determining the 24-hour survival of stored red cells.
Two methods of determining the survival of stored red cells are described: one using a double label and one using a single label. It is not suggested that one is superior, but rather both methods are presented in the hope that the personnel of laboratories engaged in determining the effectiveness of anticoagulant-preservation will follow one of the protocols presented. Were this to occur, many of the interlaboratory variations that have decreased the value of data from red cell survival studies would be decreased.
D000925:Anticoagulants / Q000494:pharmacology; D001793:Blood Preservation / Q000592:standards*; D001800:Blood Specimen Collection; D001803:Blood Transfusion / Q000379:methods / Q000592:standards*; D002860:Chromium Radioisotopes; D004905:Erythrocyte Aging / Q000187:drug effects; D004906:Erythrocyte Count; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000378:metabolism / Q000502:physiology; D006801:Humans
D000925:Anticoagulants; D002860:Chromium Radioisotopes