title: [Changes in the functional activity of the kidneys after irradiation of the para-aortic lymph nodes in patients with seminoma and lymphogranulomatosis].
abstract: During treatment of seminomas and lymphogranulomatosis, the paraaortal lymph nodes are subjected to irradiation, the dose of ionizing radiation to the renal area ranging from 12 to 48 Gy. Irradiation of the kidneys leads to both functional and organic lesions because of their anatomical proximity to the regional lymph nodes. Seventy patients with seminoma and lymphogranulomatosis who received therapeutic irradiation for the paraaortal lymph nodes were examined. Of these, 13 manifested functional lesions in the kidneys during the whole observation period, whereas in 14 patients, these abnormalities occurred after radiation therapy. In 9 patients, they were seen in the long-term period.
mesh_terms: D004407:Dysgerminoma / Q000532:radiotherapy*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D007668:Kidney / Q000528:radiation effects*; D007677:Kidney Function Tests; D008198:Lymph Nodes / Q000528:radiation effects*; D008297:Male; D011879:Radiotherapy Dosage; D013736:Testicular Neoplasms / Q000532:radiotherapy*
vernacular_title: Izmenenie funktsional'noĭ aktivnosti pochek posle oblucheniia paraaortal'nykh limfaticheskikh uzlov u bolnykh seminomoĭ i limfogranulematozom.