Amniotic band syndrome and conditions simulating disruption malformations.
Twelve cases of fetal malformation due to the amniotic band syndrome (ABS) or disruption sequence were reviewed; these included craniofacial malformations, limb defects and gastroschisis. No one case was similar to another. The initial diagnosis was correct in 5 of the 12 cases, mainly those involving limb defects. All 4 cases in which major malformations were present were initially diagnosed incorrectly. The importance of correct diagnosis mainly concerns counselling regarding the future risk of recurrence--the probability of familial recurrence of ABS is very low, whereas the risk of recurrence of a familial neural tube defect is about 5%.
D000652:Amniotic Band Syndrome / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005145:Face / Q000002:abnormalities; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D017880:Limb Deformities, Congenital; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012886:Skull / Q000002:abnormalities