title: Characterization of a polypeptide from human seminal plasma with inhibin (inhibition of FSH secretion)-like activity.
abstract: A polypeptide in preparations of 'large' form (Mr approximately 14000) material with inhibin-like activity (inhibiting FSH secretion) has been isolated from human seminal plasma. Its amino acid composition, cleavage pattern with CNBr, N-terminal sequence, and properties on reverse-phase high-performance liquid chromatography establish this inhibin-like preparation to be homogeneous. The polypeptide contains close to 130 residues, has a free N-terminal serine residue, a methionine residue in position 19, and a dibasic structure (Arg-Lys) in positions 16-17.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D003488:Cyanogen Bromide; D006801:Humans; D007265:Inhibins / Q000032:analysis*; D008297:Male; D012661:Semen / Q000032:analysis*
chemical_list: D000596:Amino Acids; D007265:Inhibins; D003488:Cyanogen Bromide