[Characteristics of chromatin breakdown in the rat thymus after exposure to fast neutrons and gamma rays].
A comparative study was made of the radiobiological aftereffects of the action of fast neutrons and gamma-rays on lymphoid tissues of rat thymus with a reference to a biochemical criterion of the interphase death of lymphocytes, i.e. the formation of polydeoxynucleotides (PDN). It was shown that the increase in the chromatin degradation was a function of dose of neutron- and gamma-radiation (up to 4 Gy). The dynamics of the PDN formation was similar with both types of radiation, but 4-6 h after neutron irradiation chromatin degradation was higher more pronounced. The RBE of neutrons varied from 3 to 2 with a radiation dose varying from 0.25 to 4 Gy.
D000818:Animals; D002843:Chromatin / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons; D005720:Gamma Rays; D008297:Male; D009502:Neutrons; D011089:Polydeoxyribonucleotides / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000528:radiation effects*; D013997:Time Factors
D002843:Chromatin; D011089:Polydeoxyribonucleotides
Osobennosti raspada khromatina timusa krys posle vozdeĭstviia bystrykh neĭtronov i gamma-lucheĭ.