Trisomy X as a possible initial chromosome change in a gastric cancer.
Primary and metastatic gastric tumors from a patient previously treated for five different cancers were cytogenetically examined by G-banding. Both types of tumors had cells with a 47,XX, +X karyotype; in addition, the primary tumor had a second clone with a 48,XX, +X, +12 karyotype. No other abnormality was found in either tumor. The lymphocytes of this patient revealed a normal female diploid karyotype.
D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D005260:Female; D006801:Humans; D007621:Karyotyping; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000235:genetics*; D014314:Trisomy; D014960:X Chromosome