Propranolol in the treatment of rage and violent behavior associated with Korsakoff's psychosis.
Propranolol controlled the rage and violent behavior of a man with alcohol withdrawal, Korsakoff's psychosis, and seizures. The authors present evidence linking Korsakoff's psychosis and alcohol withdrawal to pathophysiologic alterations in CNS adrenergic amines and receptors.
D000328:Adult; D000425:Alcohol Amnestic Disorder / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D000786:Anger / Q000187:drug effects*; D000431:Ethanol / Q000009:adverse effects; D006801:Humans; D008297:Male; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*; D011889:Rage / Q000187:drug effects*; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000503:physiopathology; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D014754:Violence
D011941:Receptors, Adrenergic; D000431:Ethanol; D011433:Propranolol