Increased intracranial pressure in adrenoleukodystrophy.
Increased intracranial pressure developed as a terminal event in a 5-year-old boy with adrenoleukodystrophy. The CSF protein concentration was 420 mg/dL. Computed tomography showed extensive areas of decreased density in the posterior cerebral white matter. At autopsy, brain weight exceeded the expected value by 20%, and white matter water content was 87.6% (expected value, 72.5%). In rare instances, brain edema may contribute to the development of increased intracranial pressure in adrenoleukodystrophy.
D000326:Adrenoleukodystrophy / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D002675:Child, Preschool; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000503:physiopathology*; D006801:Humans; D007427:Intracranial Pressure; D008297:Male
D002556:Cerebrospinal Fluid Proteins