Xeroderma pigmentosum fibroblasts including cells from XP variants are abnormally sensitive to the mutagenic and cytotoxic action of broad spectrum simulated sunlight.
D002478:Cells, Cultured; D005347:Fibroblasts / Q000502:physiology / Q000528:radiation effects; D006801:Humans; D009154:Mutation; D013472:Sunlight; D014983:Xeroderma Pigmentosum / Q000503:physiopathology*