Cadmium, copper and zinc-binding protein (metallothionein) in the liver of the water lizard Triturus pyrrhogaster.
A low-Mr copper (Cu) and zinc (Zn)-binding protein was present in the liver of a control water lizard Triturus pyrrhogaster. Cadmium (Cd) accumulated in the liver of the animals after intramuscular injections of Cd salt and was bound to Cu- and Zn-binding protein of a single isoform that had properties characteristic of metallothionein (MT). Effects of Cd loading on several essential elements in the liver and kidney were also determined.
D000818:Animals; D002104:Cadmium / Q000378:metabolism* / Q000494:pharmacology; D003300:Copper / Q000378:metabolism*; D004602:Elements / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008668:Metallothionein / Q000378:metabolism*; D014319:Triturus / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism*
D004602:Elements; D002104:Cadmium; D003300:Copper; D008668:Metallothionein; D015032:Zinc