title: Nifedipine in hypertension and heart failure.
abstract: The use of nifedipine in patients with hypertension, heart failure, and acute myocardial infarction is discussed. Data from over a ten-year period are presented. Results indicate that nifedipine, although frequently prescribed as an antianginal agent, is also useful as an antihypertensive agent, especially when used concomitantly with other drugs. Its ability to cause fluctuations in blood pressure remains a shortcoming, however.
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003692:Delayed-Action Preparations; D004359:Drug Therapy, Combination; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008750:Methyldopa / Q000008:administration & dosage; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use*; D011433:Propranolol / Q000008:administration & dosage; D012084:Renin-Angiotensin System / Q000187:drug effects
chemical_list: D003692:Delayed-Action Preparations; D008750:Methyldopa; D011433:Propranolol; D009543:Nifedipine; D007548:Isosorbide Dinitrate