Trazodone overdose: report of two cases.
Two cases of overdose due to ingestion of trazodone are described. In one case, blood collected several hours following ingestion of an estimated 4 or more grams contained a trazodone concentration of 25.7 mg/L. Recovery was uneventful. The second case did not survive and death was attributed to the ingestion of multiple drugs in combination. Both cases were analyzed by high-pressure liquid chromatography and the methodology is given.
D000328:Adult; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000506:poisoning*; D014196:Trazodone / Q000097:blood / Q000506:poisoning*
D010879:Piperazines; D014196:Trazodone