title: Structure related phylogenetic variations in brain gangliosides of vertebrates.
abstract: The concentration and composition of brain gangliosides from five brain structures of vertebrate species belonging to the classes of Chondrichthyes, Osteichthyes, Reptilia, Aves and Mammalia were investigated. The complexity of brain ganglioside composition is strikingly reduced over phyletic lines. In lower vertebrates there is only little variation in the ganglioside pattern between the different brain structures, whereas in higher vertebrates differences distinctly occurred. A similarity over phyletic lines of ganglioside pattern was only noted in phylogenetically old brain structures as for instance in the medulla oblongata and the brain stem.
mesh_terms: D000818:Animals; D001717:Birds / Q000378:metabolism; D001923:Brain Chemistry; D005399:Fishes / Q000378:metabolism; D005732:Gangliosides / Q000032:analysis*; D010802:Phylogeny; D012104:Reptiles / Q000378:metabolism; D013045:Species Specificity; D014714:Vertebrates / Q000378:metabolism*
chemical_list: D005732:Gangliosides