[Transplant conditioning and transplant size in heterotopic autologous spleen transplantation].
In an experimental study we compared two methods of preparing transplants in rabbits (n = 66): 4-5 splenic fragments with a thickness of 1 mm and graduated weight (5-800 mg) were attached onto the peritoneal peritoneum. Splenic homogenates with increasing weight (5-800 mg) were placed in 4-5 preformed pockets in the parietal peritoneum. At different postoperative intervals (maximum 42 days), a relaparotomy was performed. The regenerated splenic tissue was dissected, weighted and histologically examined. We found a linear correlation between pre- and postoperative weight. However, this correlation applies only to the homogenates with a weight of maximal 200 mg and to the fragments with a weight of maximal 300 mg. We have come to the conclusion that homogenates regenerate better than fragments.
D000818:Animals; D005260:Female; D008297:Male; D009336:Necrosis / Q000473:pathology; D009929:Organ Size; D011817:Rabbits; D012038:Regeneration; D013154:Spleen / Q000473:pathology / Q000502:physiology / Q000637:transplantation*; D013156:Splenectomy; D014182:Transplantation, Autologous
Experimentelle Studie zur Frage der Transplantatkonditionierung und Transplantatgrösse bei heterotoper autologer Milztransplantation.