title: Tumoral calcinosis, diaphysitis, and hyperphosphatemia.
abstract: Three children with hyperphosphatemic tumoral calcinosis, including 2 siblings, presented with recurrent pain and swelling of the legs. Laboratory tests, radiographs, and biopsy showed reactive new bone formation of unknown etiology in the diaphyses. The authors hypothesize a relationship between tumoral calcinosis, hyperostosis, and hyperphosphatemia and consider possible mechanisms.
mesh_terms: D000293:Adolescent; D001847:Bone Diseases / Q000097:blood / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000097:blood / Q000000981:diagnostic imaging*; D002648:Child; D004550:Elbow / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D010758:Phosphorus / Q000097:blood*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging
chemical_list: D010758:Phosphorus