title: A comment on thyrotropin measurement and evaluation.
abstract: There is a need for improvement of thyrotropin measurements in the clinical laboratory, specifically in the lower portion of the normal range. We cite realistic examples of incorrect, misleading data generated with many thyrotropin kits currently in use and propose a practical laboratory protocol to evaluate the performance of a procedure for determining thyrotropin. The protocol integrates medical physiology with analytical measurement.
mesh_terms: D005069:Evaluation Studies as Topic; D006801:Humans; D011933:Reagent Kits, Diagnostic; D013959:Thyroid Diseases / Q000097:blood / Q000175:diagnosis*; D013972:Thyrotropin / Q000097:blood*
chemical_list: D011933:Reagent Kits, Diagnostic; D013972:Thyrotropin