title: Seminoma metastatic to the orbit.
abstract: Testicular cancer is the most frequent malignancy in young adult males. Seminoma, the most frequent cell type, causes exophthalmos on a hormonal basis; actual tumor invasion of the orbit has been reported once. We report here a second case of orbital invasion by seminoma. When tumor has spread beyond the retroperitoneum, treatment with chemotherapy is usually recommended. A biopsy of the orbital metastatic tumor may be the technique with least morbidity to document tumor state prior to committing the patient to systemic chemotherapy.
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000032:analysis; D004407:Dysgerminoma / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013736:Testicular Neoplasms / Q000175:diagnosis
chemical_list: D006063:Chorionic Gonadotropin