Effect of ingested sperm on fecundity in the rat.
The intragastric administration of homologous strain epididymal sperm to adult virgin NZBW (Rt 1) female rats was shown to induce short-to long-term infertility. Infertility was associated with an early rise of genital secretory fluid IgA antisperm antibody preceding mating.
D000284:Administration, Oral; D000818:Animals; D000906:Antibodies / Q000502:physiology; D000941:Antigens / Q000008:administration & dosage* / Q000276:immunology; D005260:Female; D005836:Genitalia, Female / Q000276:immunology; D007070:Immunoglobulin A / Q000096:biosynthesis / Q000502:physiology; D007247:Infertility, Female / Q000209:etiology* / Q000276:immunology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies; D000941:Antigens; D007070:Immunoglobulin A