Hyperplastic nodules of the liver induced in rats fed bracken diet.
Hyperplastic nodules (HN) of the liver were induced in Charles River Sprague-Dawley rats (CD rats) and ACI rats fed a diet containing 30% bracken for 260 and 180 days, respectively. HN were also induced in high incidence in CD rats fed a diet containing the carcinogenic fractions of bracken extract.
D000818:Animals; D005260:Female; D006965:Hyperplasia / Q000139:chemically induced; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D010936:Plant Extracts / Q000633:toxicity*; D010945:Plants, Edible; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors
D010936:Plant Extracts