Enhancement of bone ingrowth by the use of bone matrix as a biologic cement.
In an effort to enhance bone growth into implants with porous coatings, a decalcified bone cement was used to secure fixation of the implants in canine femora. Rods with porous coatings were inserted bilaterally into the femoral medullary canals of nine dogs of varying sizes. A demineralized bone paste was used to enhance the fixation in one side, with the contralateral limb serving as a control. Pull-out testing and gross and roentgenographic examination of the specimens confirmed that the demineralized bone matrix enhanced fixation.
D000818:Animals; D001843:Bone Cements; D001857:Bone Matrix; D001858:Bone Nails; D004285:Dogs; D008855:Microscopy, Electron, Scanning; D010012:Osteogenesis; D019736:Prostheses and Implants; D013314:Stress, Mechanical; D014945:Wound Healing
D001843:Bone Cements