title: Prescription medication dependence and neuropsychologic function.
abstract: The abuse of prescription drugs is an insidious complication among patients with chronic pain. This study examines cognitive intellectual functions in patients with chronic pain who are using prescribed analgesics, sedatives and hypnotics. A comprehensive battery of psychologic tests measuring intelligence, learning, memory, sensory-perceptual integrity, motor skills and general adaptive abilities was administered to 47 subjects. The subjects were patients admitted to a chronic pain management program, and they were divided into drug-dependent, drug-abusing and non-drug-abusing groups according to strictly defined criteria. Findings indicated that the prescribed use of these medications for pain over a prolonged time is detrimental to the cognitive function of such patients and complicates their clinical management.
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics; D002908:Chronic Disease; D003071:Cognition / Q000187:drug effects; D011307:Drug Prescriptions; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007360:Intelligence / Q000187:drug effects; D007361:Intelligence Tests; D007858:Learning / Q000187:drug effects; D008297:Male; D008568:Memory / Q000187:drug effects; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects; D010146:Pain / Q000188:drug therapy*; D011597:Psychomotor Performance / Q000187:drug effects; D019966:Substance-Related Disorders / Q000523:psychology*
chemical_list: D000700:Analgesics; D006993:Hypnotics and Sedatives