Netherton's syndrome in two adult brothers.
To our knowledge, these are the first cases of almost complete Netherton's syndrome in two adult brothers born of consanguineous parents. The aromatic retinoid, etretinate, although initially worsened the eczematous manifestations, proved to be capable of reducing the primary skin lesions in one patient.
D000328:Adult; D000596:Amino Acids / Q000652:urine; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000235:genetics*; D006201:Hair Diseases / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007057:Ichthyosis / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D013577:Syndrome
D000596:Amino Acids