In vivo nuclear magnetic resonance spectroscopy of a transplanted brain tumour.
In vivo nuclear magnetic resonance 31P spectroscopy was used to demonstrate different patterns of high energy phosphate metabolism in a group of malignant tumours of glial origin. In some of the more malignant tumours a decrease in adenylate energy charge was found. This was associated with a decline in phosphocreatine and an increase in sugar phosphate and inorganic phosphorus.
D000818:Animals; D001932:Brain Neoplasms / Q000378:metabolism*; D005910:Glioma / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D009368:Neoplasm Transplantation; D010710:Phosphates / Q000378:metabolism*; D010758:Phosphorus; D051381:Rats; D011919:Rats, Inbred Strains
D010710:Phosphates; D010758:Phosphorus