Sister chromatid exchanges in betel and tobacco chewers.
The incidence of sister-chromatid exchange (SCE) was investigated in the lymphocyte chromosomes of betel and tobacco chewers. Betel chewers and betel-with-tobacco chewers showed higher yields of SCE than normal controls. Higher frequencies of SCE were also observed in individuals who chewed more than 10 betel leaves, or betel leaves-with-tobacco, per day, compared to people who chewed less than 10 betel leaves, or betel leaves-with-tobacco, per day, respectively. Subjects who had chewed betel leaves and betel leaves + tobacco for more than 10 years showed an elevated frequency of SCE.
D001114:Areca; D002478:Cells, Cultured; D003434:Crossing Over, Genetic; D006801:Humans; D008214:Lymphocytes / Q000166:cytology; D008297:Male; D010946:Plants, Medicinal; D010947:Plants, Toxic; D012854:Sister Chromatid Exchange; D014026:Nicotiana