Haemodynamic evaluation of ibopamine in severe congestive heart failure.
Ten patients suffering from refractory congestive heart failure were treated orally with Ibopamine 100 mg. The haemodynamic effects were evaluated with a Swan-Ganz catheter and thermodilution technique, 1 and 2 h after treatment. Ibopamine significantly increased the cardiac index and stroke work index, and decreased pulmonary pressure and the pulmonary and peripheral vascular resistances without affecting heart rate or blood pressure.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D006328:Cardiac Catheterization; D002302:Cardiac Output / Q000187:drug effects; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D003846:Deoxyepinephrine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004298:Dopamine / Q000031:analogs & derivatives*; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000187:drug effects
D002316:Cardiotonic Agents; C023487:ibopamine; D003846:Deoxyepinephrine; D004298:Dopamine