title: Vibratory sensory testing in acute peripheral nerve compression.
abstract: Vibratory thresholds were continually measured with a variable-amplitude vibrometer during periods of controlled median nerve compression in 12 human volunteers. Tissue fluid pressure in the carpal canal was maintained at 50 mm Hg, a level which caused a complete loss of nerve function in all subjects by 45 minutes. In all subjects vibratory thresholds proved to be the earliest test indicating a decrease in nerve function. Semmes-Weinstein pressure testing and 256 cycles/sec vibratory sensibility correlated well with measurements of vibratory thresholds and with the electrodiagnostic testing. Static and moving two-point discrimination did not become abnormal until late in the clinical testing. The vibrometer has significant potential as a clinical and research instrument in nerve compression syndromes. This study supports the use of vibratory stimuli as a noninvasive diagnostic test; it is currently undergoing evaluation in a number of clinical studies.
mesh_terms: D000328:Adult; D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D009460:Neurologic Examination / Q000295:instrumentation; D010525:Peripheral Nerves; D012684:Sensory Thresholds; D014732:Vibration