Thyroid cancer in children and teenagers.
A study of thyroid cancer in patients younger than 20 years showed most tumors to be of the differentiated type. Histological types were pure papillary adenocarcinoma (9.5%), mixed papillary and follicular adenocarcinoma (77%), pure follicular adenocarcinoma (2.7%), and medullary carcinoma (10.8%). Of the patients with differentiated carcinoma, 84% had palpable cervical lymphadenopathy and 11% had pulmonary metastasis on admission. Patients with differentiated carcinoma were followed up for a mean of 15.4 years, and patients with medullary carcinoma for a mean of 7.3 years. No patient died as a result of papillary or follicular carcinoma, but two (25%) died of medullary carcinoma. Permanent hypoparathyroidism was found in 17% of patients after total thyroidectomy.
D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000367:Age Factors; D002277:Carcinoma / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D002648:Child; D006801:Humans; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D013965:Thyroidectomy