title: Measles: extinction or evolution?
abstract: The human body is the biological environment to which measles virus must adapt. In this paper the immunity conferred by vaccination is viewed as a selective force on the evolution of this virus. The possible consequences of this type of selection pressure include an increased Ro, antigenic variation, and immune depression.
mesh_terms: D000956:Antigens, Viral / Q000276:immunology; D005075:Biological Evolution; D014644:Genetic Variation; D006801:Humans; D007114:Immunization; D008457:Measles / Q000276:immunology / Q000517:prevention & control*; D008459:Measles virus / Q000276:immunology
chemical_list: D000956:Antigens, Viral