Temperature-sensitive mutants of Mycoplasma gallisepticum.
Mycoplasma gallisepticum (MG) S6 strain was treated with nitrosoguanidine to obtain temperature-sensitive mutants. Of the 101 colonies screened, 4 were found to be temperature sensitive. These mutants and the wild type organisms were serologically and morphologically identical. Three of the 4 mutants failed to produce air sac lesions when inoculated directly into air sacs of the chicken.
D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology; D002645:Chickens / Q000382:microbiology; D009154:Mutation; D009174:Mycoplasma / Q000235:genetics* / Q000276:immunology / Q000472:pathogenicity; D013696:Temperature
D001428:Bacterial Vaccines