title: Propoxyphene dependence: problems in management.
abstract: Propoxyphene dependence presents a difficult treatment problem: the patients' subjective discomfort and concomitant craving during gradual withdrawal of the drug is more intense and more poorly tolerated than that observed with other narcotic analgesic agents. Of the six patients we describe, only one has achieved successful detoxification.
mesh_terms: D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000139:chemically induced; D011431:Dextropropoxyphene; D006801:Humans; D008297:Male; D012008:Recurrence; D012640:Seizures / Q000209:etiology; D013375:Substance Withdrawal Syndrome / Q000628:therapy; D019966:Substance-Related Disorders / Q000534:rehabilitation*
chemical_list: D011431:Dextropropoxyphene