2-Bromoethyl glycosides in glycoside synthesis: preparation of glycoproteins containing alpha-L-Fuc-(1----2)-D-Gal and beta-D-Gal-(1----4)-D-GlcNAc.
The applicability of 2-bromoethyl glycosides in carbohydrate synthesis is demonstrated by the synthesis of glycosides of alpha-L-Fuc-(1----2)-D-Gal and beta-D-Gal-(1----4)-D-GlcNAc. The bromoethyl aglycon was transformed into the methoxycarbonylethylthioethyl spacer, which allowed coupling of the sugars to proteins (BSA and KLH).
D000117:Acetylglucosamine; D055598:Chemical Phenomena; D002621:Chemistry; D005643:Fucose; D005690:Galactose; D006023:Glycoproteins / Q000138:chemical synthesis*
D006023:Glycoproteins; D005643:Fucose; D000117:Acetylglucosamine; D005690:Galactose