title: The binding of triethyllead to rat and cat hemoglobin.
abstract: Equilibrium dialysis experiments were carried out to determine the affinity constant and stoichiometry of the binding of triethyllead to rat and cat hemoglobin. The affinity constants were 4 X 10(5) M-1 and 4.5 X 10(5) M-1 for rat and cat hemoglobin, respectively, and 2 mol triethyllead combined with 1 mol hemoglobin. The previous report of a stoichiometry of 3 could not be confirmed (Byington et al., 1980).
mesh_terms: D000818:Animals; D001665:Binding Sites; D002415:Cats; D003956:Dialysis; D006454:Hemoglobins / Q000378:metabolism*; D007854:Lead / Q000097:blood*; D009942:Organometallic Compounds / Q000097:blood*; D011485:Protein Binding; D051381:Rats
chemical_list: D006454:Hemoglobins; D009942:Organometallic Compounds; D007854:Lead; C010360:triethyllead