The inhibition of dictyosome vesicle formation in higher plant cells by cytochalasin D.
We have examined the effect of cytochalasin D on secretory processes in plant root tips and pollen tubes. While confirming that inhibition of vesicle transport is the immediate effect of the drug, we now present quantitative evidence to show that vesicle formation by elements of the Golgi apparatus in plants, the dictyosomes, is progressively inhibited. Total inhibition of vesicle formation occurs within exposure times ranging from one-half to two hours. It is concluded that vesicle formation is a cytochalasin-sensitive process.
D015638:Cytochalasin D; D003572:Cytochalasins / Q000494:pharmacology*; D003313:Zea mays / Q000166:cytology / Q000187:drug effects*
D003572:Cytochalasins; D015638:Cytochalasin D