title: [Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
abstract: The drug-induced lupus erythematodes syndrome is a heterogeneous group of exogenically caused transitory autoimmunopathies . Essential knowledge has been got concerning the pathomechanism of the syndromes evoked by hydralazine, procainamide, diphenylhydantoin and Venopyronum . Though there are analogies to the systemic lupus erythematosus, we must take into consideration a diversity of diseases. Antibodies against histone have a certain diagnostic as well as pathogenetic relevance.
mesh_terms: D003937:Diagnosis, Differential; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis; D010653:Phenylbutazone / Q000009:adverse effects / Q000031:analogs & derivatives; D010672:Phenytoin / Q000009:adverse effects; D011342:Procainamide / Q000009:adverse effects; D013577:Syndrome
chemical_list: C010619:phenopyrazone; D006830:Hydralazine; D010672:Phenytoin; D010653:Phenylbutazone; D011342:Procainamide
vernacular_title: Das arzneimittelinduzierte Lupus-erythematodes-Syndrom. Pathogenese und Beziehungen zum systemischen Lupus erythematodes.