title: Use of Imugard IG500 filters for preparation of leukocyte-poor blood for cancer patients.
abstract: In order to determine the efficiency of Imugard IG500 filters in producing leukocyte-poor blood (LPB), 109 units of red cell concentrates were processed using cold (4 degrees C) or room temperature saline solution without the application of pressure to the blood bag. The results obtained in terms of red blood cell recovery, white blood cell removal, residual white blood cells, and free hemoglobin in the supernatant of the filtered units are comparable to those processed with the IBM 2991. LPB processed without pressure application to the blood bag and room temperature saline solution can be rapidly, efficiently and safely prepared in any size blood bank/transfusion service. This technique is definitely cost-saving in terms of equipment, software, space and personnel training.
mesh_terms: D001787:Blood Group Incompatibility / Q000209:etiology / Q000517:prevention & control; D001803:Blood Transfusion; D002469:Cell Separation / Q000295:instrumentation*; D017707:Erythrocyte Transfusion; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007962:Leukocytes; D009369:Neoplasms / Q000628:therapy*; D065227:Transfusion Reaction; D014462:Ultrafiltration / Q000295:instrumentation* / Q000379:methods
chemical_list: D006454:Hemoglobins