title: Isolated menarche in juvenile hypothyroidism.
abstract: Isolated menarche is an unusual presentation of the advanced sexual development relative to bone age found in some patients with juvenile hypothyroidism. A case is presented, demonstrating that hypothyroidism should be considered in the evaluation of vaginal bleeding in childhood, particularly if skeletal maturation is delayed.
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D008572:Menarche; D011629:Puberty, Precocious / Q000209:etiology*