Identification of an erythrocyte component carrying the Duffy blood group Fya antigen.
The erythrocyte component carrying the Duffy blood group antigen Fya has been identified as a 35- to 43-kilodalton protein. The protein is degraded by proteases, chymotrypsin, and Pronase, which destroy its antigenicity on intact erythrocytes. Its unusual property of aggregating on being boiled in 5 percent sodium dodecyl sulfate with 5 percent 2-mercaptoethanol distinguishes it from other erythrocyte membrane proteins described to date.
D001789:Blood Group Antigens / Q000302:isolation & purification*; D004375:Duffy Blood-Group System / Q000302:isolation & purification*; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008970:Molecular Weight
D001789:Blood Group Antigens; D004375:Duffy Blood-Group System