Effects of verapamil--a calcium inhibitor--on the vasomotor response of cortical and juxtamedullary glomeruli of the human kidney.
Cortical and juxtamedullary glomeruli of the human kidney were isolated by sieving. Verapamil, a calcium inhibitor, was added to a suspension of the glomeruli. The vasomotor response was measured by a video analyser. We were thus able to determine the modification of the cortical and juxtamedullary glomeruli surface area. Only the cortical glomeruli became vasodilated in response to the calcium inhibitor.
D006801:Humans; D066298:In Vitro Techniques; D007672:Kidney Cortex / Q000502:physiology; D007678:Kidney Glomerulus / Q000187:drug effects* / Q000502:physiology; D007679:Kidney Medulla / Q000502:physiology; D014666:Vasomotor System / Q000187:drug effects* / Q000502:physiology; D014700:Verapamil / Q000494:pharmacology*
D014700:Verapamil