title: Reconstructive surgery for the complications of pelvic irradiation.
abstract: Severe damage to the pelvic viscera is a complication of irradiation therapy that, unfortunately, cannot always be avoided. Resulting rectal and rectocolonic strictures, rectovaginal fistulas, and shortening and stenosis of the vagina present very difficult problems that frequently require a colostomy for relief and may permanently impair sexual function. The authors present a new approach to correction of these unfortunate lesions based on the use of proximal nonirradiated colon which serves as a vascular pedicle graft to correct the defect without a complicated and massive resection. Twenty-two such operations have been done with 19 satisfactory to excellent results and two total failures (one death from small bowel complications). All patterns and combinations of irradiation injury have been found amenable to this technique of repair. These have included both web and linear strictures with and without fistulas. In half of the patients, it was possible to make use of normal colon bypassed by a prior colostomy. Normal nonirradiated colon with good blood supply will heal satisfactorily to irradiated colon or rectum, thus making excision of all the irradiated tissue unnecessary. The results of this surgical approach have thus far been gratifying and warrant further trials for these distressing injuries.
mesh_terms: D003106:Colon / Q000601:surgery; D012809:Colon, Sigmoid / Q000601:surgery; D003125:Colostomy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D010388:Pelvis / Q000528:radiation effects*; D011832:Radiation Injuries / Q000601:surgery*; D012003:Rectal Fistula / Q000209:etiology / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000601:surgery; D014594:Uterine Neoplasms / Q000532:radiotherapy; D014624:Vaginal Fistula / Q000209:etiology / Q000601:surgery