In vitro release of salicylic acid from lanolin alcohols-ethylcellulose films.
Lanolin alcohols-ethylcellulose films were investigated as a potential drug delivery system for the controlled release of salicylic acid. The effects of changes in film composition, drug concentration, drug solubility, and stirrer speed on the in vitro release of salicylic acid have been examined. The drug release has been found to obey a diffusion-controlled matrix model and square root of time release profile both in the suspension and solution cases.
D000438:Alcohols; D002482:Cellulose / Q000031:analogs & derivatives; D002626:Chemistry, Pharmaceutical; D007809:Lanolin; D010968:Plasticizers; D019946:Propylene Glycol; D011409:Propylene Glycols; D012459:Salicylates / Q000008:administration & dosage*; D020156:Salicylic Acid; D012995:Solubility; D012997:Solvents
D000438:Alcohols; D010968:Plasticizers; D011409:Propylene Glycols; D012459:Salicylates; D012997:Solvents; D019946:Propylene Glycol; C013517:ethyl cellulose; D007809:Lanolin; D002482:Cellulose; D020156:Salicylic Acid