title: [Basal blood glucose oscillations in diabetics treated with microinfused insulin. Comparison between hormonal distributions by the square wave-form at various frequencies].
abstract: Basal glycemic oscillations in 3 type I-diabetics treated with continuous subcutaneous insulin infusion (CSII) and without endogenous insulin secretion have been studied. Insulin infusion with different frequencies of square wave-form basal insulin delivery (1 min and 10 min) have been utilized. Aim of the present investigation was to observe whether basal blood glucose oscillations could be affected by the frequency of basal square wave-form insulin delivery. Blood glucose has been measured at 3 min intervals for 90 min for each frequency. The glycemic patterns obtained did not show any periodism in relationship with the two frequencies engaged, hence the glycemic fluctuation, similar between the two experiments, cannot be considered as dependent on the different frequency of insulin pulses.
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D007332:Insulin Infusion Systems; D010507:Periodicity
chemical_list: D001786:Blood Glucose
vernacular_title: Oscillazioni glicemiche basali in diabetici trattati con microinfusore insulinico. Confronto fra erogazioni ormonali ad onda quadra a diversa frequenza.