title: [Acute voluntary carpipramine poisoning with ventricular tachycardia].
abstract: A case of carpipramine overdose is reported. The patient was admitted with ventricular tachycardia 4 h after taking 2.40 g of the drug. This disappeared at the sixth hour. In overdoses with other tricyclics, ventricular tachycardia was successfully treated within 30 min of starting a sodium lactate perfusion. In the case presented, reversal of the ventricular tachycardia coincided with the half-life of the drug; the effects of perfusing 1000 ml sodium lactate over 2 h seemed doubtful. This sodium resistance may be related to a relative hypokalemia (3.4 mmol X 1(-1) ). The use of sodium lactate for the treatment of overdoses with drugs with short-half lives appeared questionable.
mesh_terms: D000208:Acute Disease; D000328:Adult; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D003984:Dibenzazepines / Q000506:poisoning*; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D013610:Tachycardia / Q000139:chemically induced*
chemical_list: D014151:Anti-Anxiety Agents; D003984:Dibenzazepines; D001569:Benzodiazepines; C006922:carpipramine
vernacular_title: Intoxication volontaire aiguë par la carpipramine avec tachycardie ventriculaire.