title: [Antidromic electrical activity of the motor endings of the neuromuscular synapses in rats during acetylcholinesterase inhibition].
abstract: In acute experiments on spinal rats antidromic potential amplitude was studied in the peripheral processes of the anterior roots of the lumber segments elicited by a solitary and rhythmical stimulation of the tibial nerve before and after i. p. injection of proserine (0.3-0.5 mg/kg). After the injection solitary stimulation of the nerve evoked an antidromic electrical activity in the peripheral processes of the anterior root whereas rhythmical stimulation resulted in depression of the antidromic potentials. The antidromic potential depression seems to indicate an initial transmitter discharge into neuromuscular synapses.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D003864:Depression, Chemical; D005071:Evoked Potentials / Q000187:drug effects; D007537:Isometric Contraction / Q000187:drug effects; D009388:Neostigmine / Q000494:pharmacology; D009469:Neuromuscular Junction / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013126:Spinal Nerve Roots / Q000187:drug effects / Q000502:physiology; D013569:Synapses / Q000187:drug effects / Q000502:physiology*
chemical_list: D002800:Cholinesterase Inhibitors; D009388:Neostigmine
vernacular_title: Antidromnaia élektricheskaia aktivnost' morornykh okonchaniĭ nervno-myshechnykh sinapsov krys pri ingibirovanii atsetilkholinésterazy.