Ocular involvement in primary hyperoxaluria.
Ocular involvement from primary hyperoxaluria developed in one infant and one teenaged patient. Autopsy procedures in the first case used special histopathologic staining techniques to demonstrate a wider deposition of calcium oxalate crystals within the eye than was previously suspected. Clinical photographs and fluorescein angiograms in the older patient demonstrated a widespread retinal distribution of crystals with a periarterial predilection. This patient also demonstrated a unique acquired black macular lesion.
D000293:Adolescent; D005128:Eye Diseases / Q000150:complications / Q000473:pathology* / Q000652:urine; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007223:Infant; D008297:Male; D008661:Metabolism, Inborn Errors / Q000150:complications / Q000473:pathology* / Q000652:urine; D010070:Oxalates / Q000032:analysis / Q000652:urine*; D012160:Retina / Q000032:analysis / Q000473:pathology
D010070:Oxalates