A comparison between skin-photosensitizing (344 nm) activities of 8-methoxypsoralen and angelicin.
8-methoxypsoralen and angelicin, locally applied to the skin of the rabbit, photosensitized erythema under UV irradiation to an approximately equal extent. Incident UV irradiation was restricted mainly to 334 nm. This indicates that furocoumarin-DNA cross-links are not important in erythema induction.
D000818:Animals; D011564:Furocoumarins / Q000494:pharmacology*; D008730:Methoxsalen / Q000494:pharmacology*; D011817:Rabbits; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D012867:Skin / Q000187:drug effects* / Q000528:radiation effects; D014466:Ultraviolet Rays
D011564:Furocoumarins; D011838:Radiation-Sensitizing Agents; C011659:angelicin; D008730:Methoxsalen