Acrokeratosis paraneoplastica (Bazex' syndrome).
A 63-year-old man had acrokeratosis paraneoplastica (Bazex' syndrome) characterized by violaceous erythema and scaling of the fingers, toes, nose, and aural helices. Severe nail dystrophy was present. Extensive examination of the patient for malignant neoplasms a few months after the initial appearance of the skin changes disclosed no abnormalities, but one year after onset, an epidermoid carcinoma of the lung was found.
D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003872:Dermatitis / Q000209:etiology; D005121:Extremities; D006801:Humans; D007642:Keratosis / Q000473:pathology* / Q000628:therapy; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000473:pathology* / Q000628:therapy