Meiotic studies in two infertile males with autosomal translocations.
Meiotic studies were performed in two infertile male carriers of balanced reciprocal translocations between chromosomes 3;5 and 6;10. The first patient had severe oligozoospermia with all stages of meiosis present. The other patient was azoospermic with meiotic breakdown after the first meiotic division. A ring quadrivalent configuration was found in diakinesis in both cases.
D000328:Adult; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002905:Chromosomes, Human, 4-5; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D008540:Meiosis; D013737:Testis / Q000648:ultrastructure; D014178:Translocation, Genetic