The hazard of using chloramphenicol in food animals.
To summarize, concern has developed over the extra-label use of chloramphenicol in food-producing animals because a type of blood dyscrasia that is usually fatal to a significant subgroup of the population with an apparent predisposed sensitivity to chloramphenicol has been associated with extremely low levels of exposure to the drug. In a monitoring program, using a method of analysis that is limited as to the type of residues it can detect, USDA has found 4 to 8 animals a year that were slaughtered for use as human food that contained residue levels of chloramphenicol that approach or exceed those concentrations associated in a causal relationship with aplastic anemia in man. Given the preponderance of evidence presented above, the FDA must consider--under its mandate to protect the human health by assuring safe and effective veterinary drugs--a course of action that will preclude the availability and the use of chloramphenicol in food animals.
D000741:Anemia, Aplastic / Q000139:chemically induced; D000818:Animals; D002417:Cattle; D002701:Chloramphenicol / Q000009:adverse effects* / Q000032:analysis; D006801:Humans; D008460:Meat / Q000032:analysis*; D009132:Muscles / Q000032:analysis
D002701:Chloramphenicol