title: Mini set for iontophoresis for topical analgesia before injection.
abstract: Findings are reported on a prototype mini set for iontophoresis used to topically anesthetise the puncture spot before injection. The anesthetizing drug applied was a 2% solution of lignocaine which was iontophoresed for 10 min at a current of 1-2.5 mA. Observations were made according to a double-blind trial. After the lignocaine iontophoresis had been performed, 76% of injections were painless and 24% were reported painful. After the placebo iontophoresis, however, 87% of injections were painful. The difference is statistically significant. We conclude that iontophoresis by means of the mini set protects effectively against injection pain. The electronic structure of the device is unique and makes possible safe outpatient use.
mesh_terms: D000698:Analgesia / Q000295:instrumentation*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D006801:Humans; D007267:Injections / Q000009:adverse effects; D007478:Iontophoresis / Q000295:instrumentation*; D008012:Lidocaine / Q000008:administration & dosage
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine