title: Intraventricular administration of morphine in patients with neoplastic intractable pain.
abstract: Since February 1981, eight patients with neoplastic intractable pain have been treated by intracerebroventricular administration of small doses of morphine. Morphine was injected into the cerebrospinal fluid through a ventricular reservoir either by direct puncture or by self-administration. Clinical results were very good, and there were no deleterious effects.
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000150:complications; D006801:Humans; D007276:Injections, Intraventricular; D008175:Lung Neoplasms / Q000150:complications; D008223:Lymphoma / Q000150:complications; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D009101:Multiple Myeloma / Q000150:complications; D010148:Intractable Pain / Q000188:drug therapy* / Q000209:etiology; D010190:Pancreatic Neoplasms / Q000150:complications; D010610:Pharyngeal Neoplasms / Q000150:complications
chemical_list: D009020:Morphine