Hereditary continuous muscle fiber activity.
We describe a family with classic features of continuous muscle fiber activity (Isaacs-Mertens syndrome) appearing in an autosomal dominant pattern. Both a mother and her son had muscle stiffness and rigidity in early childhood. Because the mother's condition was not immediately apparent, we recommend a thorough examination of family members.
D000328:Adult; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009127:Muscle Rigidity / Q000175:diagnosis / Q000235:genetics*; D009222:Myotonia / Q000175:diagnosis / Q000235:genetics*; D013577:Syndrome