title: Recurrent isolated sixth nerve palsy in children.
abstract: Six children had recurrent sixth nerve palsy the average duration of which was six weeks. One youngster, after several episodes of sixth nerve palsy, had residual esotropia and underwent strabismus surgery. The average interval between recurrences was 1.3 years. Ipsilateral recurrences were a prominent feature. Thus far the recurrences of palsy in this group of patients has not been associated with any identifiable intracranial process. Multiple recurrences in the absence of any recognizable febrile illness clearly suggests that not all "benign" sixth nerve palsies in children are due to postinfectious processes. The etiology of isolated benign sixth nerve palsy remains uncertain. Benign sixth nerve palsy with recurrence may account for a larger percentage of truly "isolated" palsies in otherwise healthy youngsters than has been generally appreciated since several widely quoted papers on this subject have included individuals with multiple neurologic deficits at the time of initial presentation. This report of recurrent palsies for which etiologies were not established should not diminish the concern that there might be an identifiable, serious, cause for sudden onset of sixth nerve palsy in a youngster. The diagnosis of "benign" sixth nerve palsy is one of exclusion that is made retrospectively and only after an adequate period of close observation.
mesh_terms: D000010:Abducens Nerve; D001932:Brain Neoplasms / Q000150:complications; D001933:Brain Stem; D002648:Child; D002675:Child, Preschool; D003141:Communicable Diseases / Q000150:complications; D004172:Diplopia / Q000175:diagnosis; D004948:Esotropia / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005910:Glioma / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male; D010243:Paralysis / Q000175:diagnosis* / Q000209:etiology; D012008:Recurrence; D013285:Strabismus / Q000175:diagnosis*