beta-lipotropin increases ketone body plasma concentration in rabbits.
beta-lipotropin stimulates lipolysis in the rabbit in a dose dependent manner. Besides glycerol and free fatty acid release a significant increase of betahydroxybutyrate as well as of acetoacetate was observed while pyruvate decreased significantly. Glucose and lactate levels remained unchanged. Our data suggest that lipolysis induced by beta-LPH and its effect on ketogenesis is more important than the actual plasma concentration of insulin.
D000818:Animals; D005227:Fatty Acids / Q000097:blood; D007657:Ketone Bodies / Q000097:blood*; D008053:Lipid Mobilization / Q000187:drug effects*; D011817:Rabbits; D008083:beta-Lipotropin / Q000494:pharmacology*
D005227:Fatty Acids; D007657:Ketone Bodies; D008083:beta-Lipotropin