The obstetric significance of holoprosencephaly.
The present study reviews the entity of holoprosencephaly as it relates to obstetric diagnosis and management. Classification, embryology, and etiology are summarized. Serial sonographic findings in a recent case of holoprosencephaly complicated by hydrocephalus are presented. Criteria for antenatal diagnosis and newborn recognition as well as an approach to management are proposed.
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D001921:Brain / Q000002:abnormalities*; D005145:Face / Q000002:abnormalities*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography