[Effect of lipoproteins of different classes on platelet aggregation].
The influence of high-, low- and very-low-density lipoproteins on platelet aggregation was examined in coronary patients and normal subjects. Preincubation with high-density lipoproteins was shown to drastically inhibit platelet aggregation capacity both in normal subjects and coronary patients. Preincubation with a mixture of low- and very-low-density lipoproteins had no significant effect on platelet aggregation. The suppression of platelet aggregation by high-density lipoproteins was the most obvious in washed platelets.
D000328:Adult; D000368:Aged; D000925:Anticoagulants; D002478:Cells, Cultured; D003327:Coronary Disease / Q000097:blood*; D003470:Culture Media; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000502:physiology*; D008077:Lipoproteins, LDL / Q000502:physiology*; D008079:Lipoproteins, VLDL / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation
D000925:Anticoagulants; D003470:Culture Media; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL
Vliianie lipoproteidov razlichnykh klassov na agregatsiiu trombotsitov.