Neonatal auditory cortex lesions result in aberrant crossed corticotectal and corticothalamic projections in rats.
Ablation of one auditory cortex at birth in rats results in the formation of aberrant crossed projections from the intact hemisphere. These aberrant projections extend throughout most of the corticorecipient zone of the contralateral inferior colliculus and can be traced as far rostral as the contralateral medial geniculate nucleus. The aberrant crossed corticothalamic axons arise from layer V pyramidal neurons in the intact auditory cortex.
D000818:Animals; D000831:Animals, Newborn; D001303:Auditory Cortex / Q000293:injuries* / Q000473:pathology; D001306:Auditory Pathways / Q000473:pathology*; D005829:Geniculate Bodies / Q000473:pathology*; D051381:Rats; D013477:Superior Colliculi / Q000473:pathology*