title: Hb J-Singa (alpha-78 Asn leads to Asp), a newly discovered hemoglobin variant with the same amino acid substitution as one of the two present in Hb J-Singapore (alpha-78 Asn leads to, alpha-79 Ala leads to Gly).
abstract: A new fast-moving alpha-chain Hb variant with an Asn leads to Asp substitution at position alpha-78 was found in a French-Acadian family living in Eastern Canada. The identical substitution was reported in Hb J-Singapore, which also had an additional Ala leads to Gly substitution at position alpha-79. The new variant, which did not result in any clinical symptoms, was named accordingly, Hb J-Singa.
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D002675:Child, Preschool; D005260:Female; D006455:Hemoglobins, Abnormal; D006801:Humans; D008297:Male
chemical_list: D006455:Hemoglobins, Abnormal