Carcinoma-in-situ of the cervix: is post-hysterectomy cytology worthwhile?
The cytological records for the years 1950-1980 from South East Scotland revealed 1062 patients who had had histologically confirmed carcinoma-in-situ (or severe dysplasia) of the cervix at the time of hysterectomy. Ten cases of early 'recurrence' were detected in the first year of follow-up. During 4304 women-years of subsequent regular follow-up by vaginal vault smears, only one further confirmed recurrence was detected, this being a poorly differentiated squamous carcinoma in a 26-year-old patient, 4 years after hysterectomy. Two further patients not in regular follow-up presented clinically with invasive carcinoma. The implications for follow-up policies are discussed.
D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011183:Postoperative Complications / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014626:Vaginal Smears