title: The obstetric significance of holoprosencephaly.
abstract: The present study reviews the entity of holoprosencephaly as it relates to obstetric diagnosis and management. Classification, embryology, and etiology are summarized. Serial sonographic findings in a recent case of holoprosencephaly complicated by hydrocephalus are presented. Criteria for antenatal diagnosis and newborn recognition as well as an approach to management are proposed.
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D001921:Brain / Q000002:abnormalities*; D005145:Face / Q000002:abnormalities*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography