[Preliminary observations on the structure of the medio-intimal area of the rabbit coronary arteries. (A. Observations on 4-month-old rabbits)].
The presence of the diffuse intimal thickening (DIT) is commonly considered the structural basis for the early atherosclerotic involvement of the coronary arteries. In the ambit of a systematic morphometric comparison of experimental atherosclerotic plaques of aorta and coronaries, we have studied the coronary medio-intimal junctions of 4 months old rabbits. Both at sub-epicardic and intra-myocardic coronary arteries level we have found fiber structures similar to DIT. These findings may help explaining why coronary atherosclerosis in rabbits does not represent, in the usual experimental models, a lesion particularly severe nor of precocious appearance.
D000367:Age Factors; D000818:Animals; D001158:Arteries / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000473:pathology; D003331:Coronary Vessels / Q000648:ultrastructure*; D011817:Rabbits
Osservazioni preliminari sulla struttura dell'area di giunzione medio-intimale nelle coronarie di coniglio. (A. Osservazioni in conigli a 4 mesi dalla nascita).