title: The human glucagon gene is located on chromosome 2.
abstract: DNA samples prepared from a panel of human-mouse cell hybrids with different numbers and combinations of human chromosomes were examined for the presence of the human preproglucagon gene by hybridization with a cloned segment of the human gene. The segregation of the human glucagon gene specific DNA fragment and human chromosome 2 in these cell hybrids indicated that the preproglucagon gene (designated GCG) is on chromosome 2 in humans.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D005934:Glucagon / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000378:metabolism; D007621:Karyotyping; D051379:Mice; D052336:Proglucagon; D011498:Protein Precursors / Q000235:genetics
chemical_list: D011498:Protein Precursors; D052336:Proglucagon; D005934:Glucagon