title: Fourth International Workshop on Chromosomes in Leukemia 1982: Deletion of 5q.
abstract: In 36 cases with del(5q) examined, a type A2 deletion (q14 or q15q33) represented 56% of all cases, a type A1 deletion (q11 or q12q33) was present in 33%, and a type B deletion (q22q33) occurred in 11% of cases; therefore, all deletions were interstitial. The critical region for these cases was q22 to q33 or q34. Additional abnormalities were present in 85% of del(5q) cases; the most frequent additional abnormality was loss of one #7 (28%).
mesh_terms: D000208:Acute Disease; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002905:Chromosomes, Human, 4-5 / Q000648:ultrastructure*; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000145:classification / Q000235:genetics* / Q000473:pathology