Disturbed cardiac function possibly associated with mianserin therapy.
Two patients, who were receiving therapy with mianserin for depressive disorders, developed signs of disturbed cardiac function which resolved after mianserin therapy was discontinued. One of the patients also developed hypokalaemia which was probably caused by the drug. It is felt that these side effects warrant further research.
D000368:Aged; D001281:Atrial Fibrillation / Q000139:chemically induced; D003866:Depressive Disorder / Q000188:drug therapy; D003984:Dibenzazepines / Q000009:adverse effects*; D005260:Female; D006333:Heart Failure / Q000139:chemically induced*; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced; D008297:Male; D008803:Mianserin / Q000009:adverse effects*
D003984:Dibenzazepines; D008803:Mianserin