Elimination of ipsilateral retinotectal projections in mono-ophthalmic chick embryos.
There are two transient ipsilateral retinotectal projections in the chick embryo: a normal one, appearing with a similar projection pattern in both binocular and monocular embryos, and an additional abnormal projection appearing only in mono-ophthalmic embryos. The development and the elimination of the ipsilateral retinotectal projections in mono-ophthalmic chick embryos was investigated using horseradish peroxidase (HRP) and the fluorescent dye Rhodamine-B-Isothiocyanate (RITC) as tracers for axonal pathways. The mechanisms involved in the elimination of the ipsilateral fibers are discussed.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D002642:Chick Embryo; D004292:Dominance, Cerebral / Q000502:physiology*; D008856:Microscopy, Fluorescence; D009412:Nerve Fibers / Q000648:ultrastructure; D009416:Nerve Regeneration; D012160:Retina / Q000033:anatomy & histology*; D012683:Sensory Deprivation / Q000502:physiology*; D013477:Superior Colliculi / Q000033:anatomy & histology*; D014795:Visual Pathways / Q000033:anatomy & histology