Vitamin-B12 deficiency following therapy in gynecologic oncology.
Vitamin-B12 deficiency results from inadequate absorption of the vitamin by the distal ileum and depletion of available stores. Both radiotherapy and intestinal resection can contribute to development of this condition. The significance of this problem in gynecologic oncology is discussed and two patients are described.
D000368:Aged; D000740:Anemia / Q000209:etiology; D005260:Female; D005833:Genital Neoplasms, Female / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007082:Ileum / Q000378:metabolism / Q000528:radiation effects / Q000601:surgery; D007408:Intestinal Absorption / Q000528:radiation effects; D014806:Vitamin B 12 Deficiency / Q000209:etiology* / Q000378:metabolism