Identification of a testosterone-dependent unique volatile constituent of male mouse urine: 7-exo-ethyl-5-methyl-6,8-dioxabicyclo[3.2.1]-3-octene.
Investigations regarding the chemical composition of the volatiles in male mouse urine have recently enabled the structural elucidation of a hitherto unreported urinary component, 7-exo-ethyl-5-methyl-6,8-dioxabicyclo[3.2.1]-3-octene. This compound's uniqueness to mouse urine and its dependence on testosterone levels in the male suggest its probable role as a mouse pheromone or pheromone adjuvant.
D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000652:urine*; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds / Q000652:urine*; D002369:Castration; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010675:Pheromones / Q000652:urine*
D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D001952:Bridged-Ring Compounds; D010675:Pheromones; C040729:3,4-dehydrobrevicomin