Pharmacological profile of wet-dog shaking induced by electrical stimulation of the fornix in rats.
Electrical stimulation of the fornix evoked body shaking in conscious rats. Stimulation of nucleus interstitialis stria terminalis failed to cause shaking. Fornix-evoked shaking was most consistently inhibited by drugs that modify brain noradrenergic function.
D000241:Adenosine / Q000494:pharmacology; D000625:Aminooxyacetic Acid / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects*; D004298:Dopamine / Q000502:physiology; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D005260:Female; D007276:Injections, Intraventricular; D008032:Limbic System / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology; D009271:Naltrexone / Q000494:pharmacology; D009434:Neural Pathways / Q000502:physiology; D010830:Physostigmine / Q000494:pharmacology; D010852:Picrotoxin / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D000241:Adenosine; D000625:Aminooxyacetic Acid; D001285:Atropine; D004298:Dopamine; D009270:Naloxone; D009271:Naltrexone; D010830:Physostigmine; D010852:Picrotoxin; D011433:Propranolol; D012701:Serotonin; D005680:gamma-Aminobutyric Acid