title: [Histo- and pathogenesis of necrobiosis lipoidica (diabeticorum)].
abstract: 50 necrobiosis lipoidica cases which were observed in the last twelve years at the Dept. of Dermatology of the University of Essen were examined. Our studies showed that local metabolic and vascular disturbances play an important factor in the histo- and pathogenesis of the necrobiosis lipoidica (diabeticorum).
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002196:Capillaries / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D004727:Endothelium / Q000473:pathology; D004798:Enzymes / Q000378:metabolism; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008928:Mitochondria / Q000648:ultrastructure; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D009335:Necrobiosis Lipoidica / Q000175:diagnosis / Q000473:pathology*; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology; D012907:Smoking
chemical_list: D004798:Enzymes
vernacular_title: Zur Histo- und Pathogenese der Nekrobiosis lipoidica (diabeticorum).