Markedly elevated serum testosterone in pregnancy without fetal virilization.
A 37-year-old woman with a history consistent with polycystic ovarian disease became pregnant and developed exceedingly high levels of serum testosterone. The female fetus showed no evidence of virilization. A clinical diagnosis of bilateral theca lutein cysts was made. Modes of fetal protection from maternal androgenemia as well as suggestions for future investigations are discussed.
D000328:Adult; D005260:Female; D005333:Fetus / Q000502:physiology*; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D013739:Testosterone / Q000097:blood*
D013739:Testosterone