title: [Biochemical and ultrastructural changes of the liver during the loss of cerebral function].
abstract: Biochemical and electron optical changes in the liver cell were recorded at the experimental brain death in dogs. The investigation results refer to a hypoxic lesion at the beginning of the brain death despite of a strong flow in the hepatic artery and the portal vein. An enlarged shunt flow is discussed to be the cause.--A distinct recovery tendency shows the morphological picture at the state of the brain death despite reducing the hepatic blood-flow and without aimed therapeutic measures. This recovery tendency appears better in the electron microscopical finding than in the behaviour of the cell metabolites.
mesh_terms: D000227:Adenine Nucleotides / Q000378:metabolism; D000818:Animals; D001926:Brain Death; D004285:Dogs; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D007773:Lactates / Q000378:metabolism; D019344:Lactic Acid; D008099:Liver / Q000378:metabolism* / Q000648:ultrastructure; D008112:Liver Glycogen / Q000378:metabolism; D008854:Microscopy, Electron; D008930:Mitochondria, Liver / Q000648:ultrastructure; D008933:Mitochondrial Swelling; D013997:Time Factors; D014617:Vacuoles / Q000648:ultrastructure
chemical_list: D000227:Adenine Nucleotides; D007773:Lactates; D008112:Liver Glycogen; D019344:Lactic Acid
vernacular_title: Biochemische und ultrastrukturelle Veränderungen der Leber bei zerebralem Funktionsausfall.