Pentazocine-induced agranulocytosis.
A 46-year-old man with pentazocine-induced agranulocytosis is described. In previously reported cases of a complete absence of mature neutrophils in the peripheral blood and bone marrow the patients had undergone marrow-depressing treatment with radiation and antineoplastic drugs. This case is unique in that the patient had complete agranulocytosis without predisposing factors.
D000380:Agranulocytosis / Q000139:chemically induced*; D002512:Cephalothin / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D010423:Pentazocine / Q000009:adverse effects*
D005839:Gentamicins; D002512:Cephalothin; D010423:Pentazocine