Cutaneous carcinoma in psoriatic patients treated with PUVA.
Eight of 216 psoriatic patients treated at The London Hospital with photochemotherapy (PUVA) have developed a total of twenty-five skin carcinomata. The type and site of tumour are discussed with special reference to the importance of PUVA compared with other risk factors. We suggest that a history of previous skin carcinoma, arsenic therapy or radiotherapy are relative contra-indications to PUVA therapy for psoriasis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001913:Bowen's Disease / Q000209:etiology; D002280:Basal Cell Carcinoma / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000209:etiology; D005260:Female; D006801:Humans; D007636:Keratoacanthoma / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy / Q000009:adverse effects*; D010778:Photochemotherapy / Q000009:adverse effects*; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*; D012306:Risk; D012871:Skin Diseases / Q000209:etiology; D012878:Skin Neoplasms / Q000209:etiology*