[Mechanical activity of the system of contractile proteins, energy supply of the myocardium and disruption of calcium transport in inflammatory lesions of the myocardium].
In rabbit experiments it has been shown that in toxico-allergic myocarditis the disordered utilization of ATP energy is responsible for acute insufficiency of the myocardial contractile function, which results in a marked energy deficiency due to mitochondrial damage, the Ca2+ absorbtion and binding by the fragmented sarcoplasmatic reticulum being diminished.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002682:Chinchilla; D004734:Energy Metabolism; D004837:Epinephrine; D006967:Hypersensitivity / Q000503:physiopathology; D009124:Muscle Proteins / Q000502:physiology*; D009200:Myocardial Contraction; D009205:Myocarditis / Q000139:chemically induced / Q000503:physiopathology*; D009206:Myocardium / Q000378:metabolism*
D009124:Muscle Proteins; D002118:Calcium; D004837:Epinephrine
Mekhanicheskaia aktivnost' sistemy sokratitel'nykh belkov, énergeticheskaia obespechennost' miokarda i narushenie transporta kal'tsiia pri vospalitel'nykh porazheniiakh miokarda.