title: Stage IV-S neuroblastoma involving the liver and ectopic liver. Report of an unusual case.
abstract: Stage IV-S (special) neuroblastoma involving the liver and ectopic liver attached to the left adrenal gland of a 38-day-old girl was reported. At surgery, the ectopic liver with neuroblastoma metastases was excised, and the liver was biopsied. The histologic features of neuroblastoma involving hepatic tissue were quite similar in the liver and the ectopic liver. Eighteen months after surgery, the patient was doing well after treatment with less intensive chemotherapy. No similar case has been reported in the literature, and study of this case indicates that the hypothesis of fetal hematogenous metastasis proposed by Wieberdink does not suffice to explain the pathogenesis of extensive involvement of the liver in Stage IV-S neuroblastoma.
mesh_terms: D000311:Adrenal Glands / Q000002:abnormalities; D005260:Female; D006801:Humans; D007223:Infant; D007813:Laparotomy; D008099:Liver / Q000002:abnormalities*; D008113:Liver Neoplasms / Q000473:pathology*; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000473:pathology*