title: Fournier's gangrene: report of 20 patients.
abstract: Synergistic necrotizing fasciitis of the penis and scrotum was described first by Fournier and remains a rare but life-threatening disease. In Fournier's initial description the process was believed to be idiopathic. During the last 10 years we have treated 20 patients with Fournier's gangrene and a definite urologic or colorectal cause could be identified as the source of the infection in 19 (95 per cent). Despite the use of broad-spectrum antibiotics and aggressive surgical débridement the mortality rate was 45 per cent.
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D005208:Fasciitis / Q000209:etiology; D005734:Gangrene / Q000209:etiology* / Q000628:therapy; D005832:Genital Diseases, Male / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000382:microbiology*; D012189:Retrospective Studies; D012611:Scrotum / Q000382:microbiology*; D014547:Urinary Diversion
chemical_list: D000900:Anti-Bacterial Agents