[Incorporation of labeled sex hormones into the ependyma of the mediobasal hypothalamus of rats after intraperitoneal and intraventricular administration].
Histoautoradiography was used to demonstrate the ability of ependyma element of the 3d brain ventricle to incorporate the label after intraperitoneal and intraventricular injection of labeled sexual hormones. The least label incorporation after intraventricular injection of 3H-estradiol and 3H-testosterone and the maximal label incorporation after intraperitoneal injection of 3H-estradiol was demonstrated by beta 1-tanicytes. The basal processes of these cells terminate in the lateral part of the external zone of the median eminence where gonadoliberin is released to the portal capillaries of the hypophysis. The data obtained warrant an assumption that beta 1-tanicytes are responsible for the transport of sexual hormones primarily from the pericapillary space of the median eminence of the hypothalamus to the cerebrospinal fluid, thereby possibly taking part in the regulation of gonadoliberin release to the portal circulation of the hypophysis.
D000818:Animals; D004805:Ependyma / Q000378:metabolism*; D004958:Estradiol / Q000008:administration & dosage / Q000378:metabolism*; D007033:Hypothalamus, Middle / Q000378:metabolism*; D007274:Injections, Intraperitoneal; D007276:Injections, Intraventricular; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013739:Testosterone / Q000008:administration & dosage / Q000378:metabolism*; D014316:Tritium
D014316:Tritium; D013739:Testosterone; D004958:Estradiol
Vkliuchenie mechenykh polovykh gormonov v ependimu mediobazal'nogo gipotalamusa krys posle vnutribriushinnogo i vnutrizheludochkovogo ikh vvedeniia.