Evaluation of screening tests for detecting sacral autonomic neuropathy in diabetes mellitus. A preliminary study.
In 6 patients with diabetes mellitus and 6 non-diabetic "controls" referred for urological assessment, sacral electromyelography (SER) and electrical stimulation of the anal reflex were compared with pressure/flow videocystourethrography (VCU) for the detection of sacral neuropathy, whilst electrocardiography (ECG) was used to screen for generalised autonomic neuropathy. Five diabetics had evidence of a neuropathic bladder on VCU and on electrical stimulation all 5 had an absent anal reflex, which may thus prove to be a simple, reliable, non-invasive screening test for sacral neuropathy.
D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000503:physiopathology; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis*; D003929:Diabetic Neuropathies / Q000175:diagnosis*; D004562:Electrocardiography; D004576:Electromyography; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012021:Reflex, Abnormal; D012445:Sacrococcygeal Region; D014567:Urography