[Radiomodifying action of 8-azahypoxanthine].
In experiments on mice it was established that 8-azahypoxanthine has a slight radiosensitizing effect on haemopoietic stem cells and leucotic cells. The pattern of the changes observed has prompted an assumption that the preparation used has an inhibitory action on the post-irradiation recovery.
D000818:Animals; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D004353:Drug Evaluation, Preclinical; D007042:Hypoxanthines / Q000494:pharmacology* / Q000627:therapeutic use; D007942:Leukemia, Experimental / Q000401:mortality / Q000532:radiotherapy; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000401:mortality / Q000532:radiotherapy; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology* / Q000627:therapeutic use; D013154:Spleen / Q000187:drug effects / Q000528:radiation effects
D007042:Hypoxanthines; D011838:Radiation-Sensitizing Agents; C000149:8-azahypoxanthine
Radiomodifitsiruiushchee deĭstvie 8-azagipoksantina.