Irradiation scheme using three daily fractions in the radiation therapy of pharyngeal and oral carcinomas.
A group of 34 patients were treated by irradiation using 3 daily fractions of 1 Gy each at 4 h intervals. The overall TD in all of the patients was 60 Gy administered within 26 days. The irradiation was carried out by telecurietherapy utilizing 60Co. Twenty-eight patients had the tumor in the oropharynx, 1 in the hypopharynx, 1 in the oro- and hypopharynx and 4 in the oral cavity. There was a prevalence of advanced clinical stages. At present 25 of the patients are living, 21 of them without clinical symptoms of the disease. The skin reacted to irradiation only with a slight erythema and hyperpigmentation. Irradiation reactions in the oropharyngeal and oral mucosa were grave and were accompanied by significant subjective complaints. No post-irradiation complications were observed.
D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D003037:Cobalt Radioisotopes; D006801:Humans; D007249:Inflammation; D009059:Mouth Diseases / Q000209:etiology; D009061:Mouth Mucosa / Q000528:radiation effects; D009062:Mouth Neoplasms / Q000532:radiotherapy*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D009960:Oropharynx; D010610:Pharyngeal Neoplasms / Q000532:radiotherapy*; D011379:Prognosis; D011867:Radioisotope Teletherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D013997:Time Factors
D003037:Cobalt Radioisotopes