title: Intrapericardial teratoma in the newborn.
abstract: Two cases of intrapericardial teratomas occurring in the newborn are reported. The first was a cystic, well differentiated tumour which was totally excised. The child was alive and well with no evidence of the disease 10 months later. The second was a predominantly solid teratoma which consisted of both mature and immature tissues. It was removed but recurred 2 months later with pleural and pericardial invasion. The patient underwent reoperation but death occurred 9 days after surgical treatment. The recurrence was histologically similar to the primary tumour. The second case is probably the first malignant intrapericardial teratoma described in a neonate. Its morphology and clinical behaviour suggest that, as in ovarian and sacrococcygeal teratomas, the presence of immature neuroepithelium carries a poor prognosis. In such cases radio- or chemotherapy should be performed.
mesh_terms: D004452:Echocardiography; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D010490:Pericardial Effusion / Q000209:etiology; D010496:Pericardium / Q000473:pathology*; D013724:Teratoma / Q000473:pathology* / Q000601:surgery