title: [Experimental and clinical characteristics of the Soviet antidepressant inkasan].
abstract: Inkasan (3-methyl-8-methoxy-3H, 1,2,5,6- tetrahydropyrazine /1.2.3-ab/-beta-carboline hydrochloride) has pharmacological properties characteristic of antidepressants. The clinical antidepressant effect of inkasan is combined with stimulating action. The drug is primarily indicated for patients in whom adynamic (anergic) disturbances are predominant in the clinical picture of depression.
mesh_terms: D000661:Amphetamine / Q000008:administration & dosage; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001058:Apomorphine / Q000037:antagonists & inhibitors; D001679:Biogenic Amines / Q000378:metabolism; D001921:Brain / Q000187:drug effects; D002243:Carbolines / Q000494:pharmacology / Q000627:therapeutic use*; D002415:Cats; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D051379:Mice; D011817:Rabbits; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors
chemical_list: D000928:Antidepressive Agents; D001679:Biogenic Amines; D002243:Carbolines; D007211:Indoles; C027473:metralindole; D012110:Reserpine; D000661:Amphetamine; D001058:Apomorphine
vernacular_title: Eksperimental'naia i klinicheskaia kharakteristika otechestvennogo antidepressanta inkazana.