title: Prophylactic lidocaine in suspected acute myocardial infarction.
abstract: We gave 50 consecutive patients with suspected acute myocardial infarction prophylactically lidocaine 300 mg intramuscularly and 100 mg intravenously. Although therapeutic plasma levels were reached, 2 of 24 (8%) patients with acute myocardial infarction had ventricular tachycardia or ventricular fibrillation and 3 of 50 (6%) became hypotensive during the first hour of lidocaine.
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000009:adverse effects* / Q000097:blood / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000517:prevention & control*
chemical_list: D008012:Lidocaine