title: Magnetic resonance signal intensity patterns obtained from continuous and pulsatile flow models.
abstract: The purpose of this investigation was to extend previous steady state flow studies with magnetic resonance (MR) to pulsatile flow measurements obtained with gated cardiac techniques in man with a pulsatile artificial heart device. Bovine blood and a solution of MnCl2 were studied. Correlation was made with complex and time-varying MR signals observed in the descending aorta on cardiac gated images obtained through the midthorax. MR signals from flowing fluids represent velocity distribution as shown in a velocity profile, and laminar flow is distinguished from nonlaminar. At very slow flow rates, signal intensity is lower than background. As the rate is increased, paradoxical enhancement occurs followed by loss of signal, which is complete at 7 liters per minute with fluid and 15 liters per minute with blood. These areas correspond to maximum fluid velocities of 41 and 88 cm/sec, respectively.
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D002417:Cattle; D006321:Heart / Q000502:physiology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D012212:Rheology