[Comparison of diflunisal and tilidine in tumor pain].
In an open study in patients with tumour-induced pain the analgetic effects of the prostaglandin-inhibiting compound diflunisal and the centrally-acting analgetic tilidine N were compared. A dosage of 1 g diflunisal was found to be equivalent to 50 drops of tilidine N and to be subjectively well-tolerated. In the pain-relieving therapy of tumour patients diflunisal appears to offer a genuine alternative to centrally-acting analgetics.
D000368:Aged; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D004061:Diflunisal / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy*; D012459:Salicylates / Q000627:therapeutic use*; D013993:Tilidine / Q000009:adverse effects / Q000627:therapeutic use*
D003509:Cyclohexanecarboxylic Acids; D012459:Salicylates; D004061:Diflunisal; D013993:Tilidine
Vergleich von Diflunisal und Tilidin bei Tumorschmerzen.