[Concentration of glucose in the tissues of glial tumors of the brain in rats with artificial hyperglycemia of short duration].
The glucose content in the tissues of rat brain glial tumors and in the brain tissue during short-term induced hyperglycemia was studied. It was shown that in artificial increase of the concentration of glucose in blood, its content in the tumor grows sharply and exceeds considerably the level of this metabolite in the brain tissue. In distinction from the brain tissue, the tumor was marked by a high rate of glucose consumption and utilization under these conditions. It is concluded that brain glial tumors are also capable of increasing glucose consumption in artificial hyperglycemia. It is suggested the the accumulation of glucose by the tumor creates the preconditions for improving the efficacy of radiotherapy combined with short-term artificial hyperglycemia in the management of brain glial tumors.
D000818:Animals; D001254:Astrocytoma / Q000032:analysis*; D001786:Blood Glucose / Q000032:analysis; D001932:Brain Neoplasms / Q000032:analysis* / Q000532:radiotherapy; D005260:Female; D005947:Glucose / Q000008:administration & dosage* / Q000032:analysis; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage; D051381:Rats
D001786:Blood Glucose; D011838:Radiation-Sensitizing Agents; D005947:Glucose
Soderzhanie gliukozy v tkaniakh glial'nykh opukholeĭ golovnogo mozga krys pri iskusstvennoĭ kratkovremennoĭ giperglikemii.