Suppression of plasma cortisol after oral administration of oxazepam in man.
In seven healthy male subjects plasma cortisol was measured at 20 min intervals from 07.00 to 13.00 h, during a drug free control test and after oral administration of 30 and 60 mg oxazepam. A significant suppression of the plasma cortisol levels for about 2 h after 30 mg oxazepam, and for about 3 h after 60 mg oxazepam was observed. The suppression wore off before the oxazepam plasma concentration started to decline significantly.
D000284:Administration, Oral; D000328:Adult; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D010076:Oxazepam / Q000097:blood / Q000494:pharmacology*
D010076:Oxazepam; D006854:Hydrocortisone