title: Cryosurgery in the management of cervical intraepithelial neoplasia.
abstract: Cryosurgery is an outpatient modality capable of destroying cervical intraepithelial neoplasia (CIN). Among 770 patients treated with cryosurgery who had at least two follow-up Papanicolaou smears, a persistence of CIN was noted in 10%. It was more difficult to destroy CIN III disease and large lesions (more than 50% of the cervix involved), although grade appeared to be more important than size of the lesion. Many patients with a persistent lesion were retreated as outpatients; as a result, in more than 96% of the 770 patients the lesion was eradicated.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003452:Cryosurgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000601:surgery*