title: Laryngeal edema as the only symptom of hypersensitivity to salicylic acid and other substances.
abstract: Idiosyncrasy to salicylic acid and related substances is well known, the most common symptoms being asthma, rhinorrhea and urticaria. We here describe two cases whose only symptoms were hoarseness and in which inspection revealed laryngeal edema when the patients ingested any of these substances. In cases of chronic recurring hoarseness, a history should be taken with respect to such hypersensitivity and suspect cases should be challenged, since a strict diet may improve the symptoms.
mesh_terms: D000328:Adult; D001241:Aspirin / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006685:Hoarseness / Q000139:chemically induced; D006801:Humans; D007819:Laryngeal Edema / Q000139:chemically induced*; D008297:Male; D012459:Salicylates / Q000009:adverse effects*
chemical_list: D012459:Salicylates; D001241:Aspirin