[Squamous epithelial carcinoma of the anorectal junction in Crohn disease with an anal fistula of many years' duration].
A squamous-cell carcinoma of the anorectal junction had developed from a chronic anal fistula in a 27-year-old woman with Crohn's disease who had been suffering from anal and rectovaginal fistulas for many years. In view of their cancerogenic potential, chronic fistulas associated with Crohn's disease must be followed up closely by clinical examination, endoscopy and biopsy. If surgery is indicated, resection of such fistulas should be considered at an early stage.
D000328:Adult; D001003:Anal Canal; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D006801:Humans; D012003:Rectal Fistula / Q000150:complications / Q000601:surgery; D012004:Rectal Neoplasms / Q000150:complications*; D012006:Rectovaginal Fistula / Q000150:complications / Q000601:surgery
Plattenepithelkarzinom des anorektalen Uberganges bei Morbus Crohn mit langjährigem analem Fistelleiden.