title: N-acetyl-beta-D-glucosaminidase in lymphocytes of workers exposed to benzene and its homologues.
abstract: In 108 workers having occupational contact with benzene and its homologues by 1 to 122 months, the activity of N-acetyl-beta-D-glucosaminidase (NAG) within the peripheral blood lymphocytes was estimated by means of cytochemical method. The benzene, the toluene and the xylene concentration at work stands was equal to 0-370, 0-580 and 0-560 mg/cu . m, respectively. In 41 workers having the service time equal to 55-122 months the NAG deficiency within the lymphocyte lysosomes was stated. Above phenomenon is probably due to disintegration of lysosomes caused by lipophilic properties of benzene.
mesh_terms: D000118:Acetylglucosaminidase / Q000097:blood*; D000293:Adolescent; D000328:Adult; D001554:Benzene / Q000633:toxicity*; D004781:Environmental Exposure; D005260:Female; D006596:Hexosaminidases / Q000097:blood*; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008875:Middle Aged
chemical_list: D006596:Hexosaminidases; D000118:Acetylglucosaminidase; D001554:Benzene