Failure to correlate urinary MHPG with clinical response to amitriptyline.
On the basis of studies carried out in a group of 44 patients with endogenous depressive illness, the authors conclude that MHPG in urine is not a good predictor of response to amitriptyline treatment. There are no correlations between MHPG level and clinical improvement after 2 weeks' treatment and with final results of the therapy.
D000639:Amitriptyline / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000652:urine; D003866:Depressive Disorder / Q000188:drug therapy* / Q000652:urine; D006018:Glycols / Q000652:urine*; D006801:Humans; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D011379:Prognosis; D011569:Psychiatric Status Rating Scales
D006018:Glycols; D000639:Amitriptyline; D008734:Methoxyhydroxyphenylglycol