Radiosensitization of Meth-A fibrosarcoma in mice by Lonidamine.
Isogenic male BALB/c mice bearing Meth-A tumors in the ascites form were used. The effects of Lonidamine and irradiation both alone and in combination were studied. Lonidamine administered intraperitoneally produced a significant enhancement of irradiation effects.
D000818:Animals; D000970:Antineoplastic Agents; D005354:Fibrosarcoma / Q000139:chemically induced / Q000628:therapy*; D007191:Indazoles / Q000627:therapeutic use*; D008297:Male; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D011720:Pyrazoles / Q000627:therapeutic use*; D011836:Radiation Tolerance; D013997:Time Factors
D000970:Antineoplastic Agents; D007191:Indazoles; D011720:Pyrazoles; D008748:Methylcholanthrene; C016371:lonidamine