title: Suppression of PGO waves in the kitten: anatomical effects on the lateral geniculate nucleus.
abstract: Bilateral mesencephalic electrolytic lesions were performed in 2-week-old kittens, in order to suppress the ascending ponto-geniculo-occipital activity. The subsequent anatomical development of the lateral geniculate nucleus was analyzed. A significant maturational deficit was evidenced in 5-week-old experimental kittens as compared to age-paired controls. It is concluded that a lesion in the X area impairs the maturation of CNS. The relationship between this area (the phasic components of paradoxical sleep) and the maturation of CNS are still to be demonstrated.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D001143:Arousal; D002415:Cats; D002452:Cell Count; D005829:Geniculate Bodies / Q000166:cytology / Q000254:growth & development / Q000502:physiology*; D009474:Neurons / Q000166:cytology; D009778:Occipital Lobe / Q000502:physiology*; D011149:Pons / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology