title: Exercise-induced pulmonary hemorrhage in thoroughbred horses: response to furosemide or hesperidin-citrus bioflavinoids.
abstract: Of 61 horses with a history of exercise-induced pulmonary hemorrhage and treated with furosemide 4 hours prior to racing, 34 (55.7%) continued to bleed. Of 24 horses with exercise-induced pulmonary hemorrhage that were not treated with furosemide prior to racing, 17 (70.8%) still bled. There was no statistically significant difference between the treated and the nontreated groups. Of 45 horses given hesperidin-citrus bioflavinoids, 38 (84.4%) bled when exercised 90 days later. There was no statistically significant difference between the results for hesperidin-citrus bioflavinoid-treated horses and those for horses known to stop bleeding without any treatment.
mesh_terms: D000818:Animals; D005419:Flavonoids / Q000627:therapeutic use*; D005665:Furosemide / Q000627:therapeutic use*; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D006569:Hesperidin / Q000627:therapeutic use*; D006734:Horse Diseases / Q000209:etiology / Q000517:prevention & control*; D006736:Horses; D008171:Lung Diseases / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D005082:Physical Exertion
chemical_list: D005419:Flavonoids; D005665:Furosemide; D006569:Hesperidin