Papillary-cystic neoplasm of the pancreas. Report of two cases and review of the literature.
Two cases of papillary-cystic neoplasm of the pancreas are reported in women aged 22 and 23 years. The patient in the first case presented with acute abdominal pain and hemoperitoneum. This form of presentation has not been previously reported. This type of pancreatic tumor is very rare, exclusively affecting young women, and has a good prognosis despite its various histologic features, which suggest a malignant appearance. The authors consider this neoplasm as having an acinar origin because in the cells of one of the patients we observed ultrastructurally the presence of abundant rough endoplasmatic reticulum with formation of annulate lamellae and a few prezymogen granules.
D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010181:Pancreatic Cyst / Q000473:pathology / Q000648:ultrastructure; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000648:ultrastructure