[In vitro electrically activated blood--an endogenous thrombogenic substance for the blocking of arteries supplying tumors and the microcirculation of tumor tissue--an experimental study].
Endovasal transcatheteral blockage of arteries supplying tumours is a clinically tested palliative measure and can also be used preoperatively to reduce intraoperative bleeding and the spread of tumour cells. In recent years several, mainly exogenic, substances have been used along with autologous muscle slurry and extracorporally produced autologous thromboses. Blood which has been exposed to the in-vitro effect of anodic direct current behaves like an endogenic thrombogenic substance. This can be used to block the microcirculation and the main artery of an organ, which results in its total dysfunction and loss of the parenchyma.
D000818:Animals; D004558:Electric Stimulation; D004621:Embolization, Therapeutic / Q000379:methods; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D008833:Microcirculation; D009369:Neoplasms / Q000098:blood supply* / Q000628:therapy; D009360:Neoplastic Cells, Circulating; D012078:Renal Artery Obstruction / Q000209:etiology*; D013552:Swine; D013556:Swine, Miniature; D013927:Thrombosis / Q000209:etiology*
Das in-vitro elektrisch aktivierte Blut--eine körpereigene thrombogene Substanz zum Verschluss der tumorversorgenden Arterien und der Mikrozirkulation des Tumorgewebes--Eine experimentelle Studie.