New method for the collection of cerebrospinal fluid from the cisterna magna of conscious dogs.
We have developed a catheter system than can be implanted chronically into the cisterna magna of the dog to obtain serial samples of cerebrospinal fluid (CSF) for up to 8 wk. A direct access to the CSF of the cisterna magna provided an opportunity to determine also base-line values of CSF sodium, potassium, norepinephrine, epinephrine, and angiotensin II immunoreactivity and compare relative differences in the concentration of these variables between the central and peripheral compartments.
D000804:Angiotensin II / Q000134:cerebrospinal fluid; D000818:Animals; D002404:Catheterization / Q000379:methods*; D002555:Cerebrospinal Fluid / Q000032:analysis*; D002946:Cisterna Magna / Q000032:analysis*; D004285:Dogs; D004837:Epinephrine / Q000134:cerebrospinal fluid; D009638:Norepinephrine / Q000134:cerebrospinal fluid; D011188:Potassium / Q000134:cerebrospinal fluid; D012964:Sodium / Q000134:cerebrospinal fluid
D000804:Angiotensin II; D012964:Sodium; D011188:Potassium; D009638:Norepinephrine; D004837:Epinephrine