title: Noncovalent complexes of diadenosine 5',5"'-P1,P4-tetraphosphate with divalent metal ions, biogenic amines, proteins and poly(dT).
abstract: Diadenosine 5',5'''-P1,P4-tetraphosphate was shown by circular dichroic measurements to bind to metal ions (Mg2+, Ca2+, Mn2+, Co2+, Zn2+), to biogenic amines (cadaverine, putrescine, spermidine, spermine), to L-arginine, to proteins (lysozyme, bovine serum albumin, Arg-rich histone f3, Lys-rich histone), and to poly(dT). Most cations effect destacking of the intramolecular adenine rings. Poly(dT) bound to the dinucleotide with a stoichiometry of 2 residues TMP per molecule of adenosine 5',5'''-P1,P4-tetraphosphate.
mesh_terms: D000227:Adenine Nucleotides; D001679:Biogenic Amines; D002413:Cations, Divalent; D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D015226:Dinucleoside Phosphates; D008670:Metals; D011071:Poly T; D011089:Polydeoxyribonucleotides; D011485:Protein Binding
chemical_list: D000227:Adenine Nucleotides; D001679:Biogenic Amines; D002413:Cations, Divalent; D015226:Dinucleoside Phosphates; D008670:Metals; D011089:Polydeoxyribonucleotides; D011071:Poly T; C020733:diadenosine tetraphosphate