Effects of nitrous oxide exposure on Met-enkephalin levels in discrete areas of rat brain.
Rat were exposed to 80% nitrous oxide in oxygen for 1 and 18 h. Met-enkephalin levels in the dorsal raphé, medial thalamus, periaqueductal grey, raphé magnus and locus coeruleus were measured by radioimmunoassay in control and treated animals. There was no change in Met-enkephalin levels at either time point in any of the brain areas examined.
D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D004723:Endorphins / Q000032:analysis; D004744:Enkephalin, Methionine / Q000032:analysis*; D008297:Male; D009609:Nitrous Oxide / Q000494:pharmacology*; D010146:Pain / Q000502:physiology; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D004723:Endorphins; D004744:Enkephalin, Methionine; D009609:Nitrous Oxide