Natural history of experimental histoplasmic choroiditis in the primate. I. Clinical features.
The clinical features of the long-term (3-year) natural history of experimental histoplasmic choroiditis in primates are documented in this report. The acute choroiditis resolved into four types of lesions: chorioretinal adhesions (atrophic scars) (2%); retinal pigment epithelial window defects (21%); subclinical lesions (19%); and "disappearing" lesions (58%). It was noted that the most obvious, acute lesions tend to disappear by clinical examination with long-term follow up. No subretinal neovascularization or spontaneous "reactivation" was observed.
D000818:Animals; D001284:Atrophy; D002829:Choroid / Q000473:pathology; D002833:Choroiditis / Q000175:diagnosis* / Q000473:pathology; D002921:Cicatrix / Q000473:pathology; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006660:Histoplasmosis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008251:Macaca; D008253:Macaca mulatta; D010781:Photography; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012160:Retina / Q000473:pathology; D013997:Time Factors