title: Functional single ventricle: cardiorespiratory response to exercise.
abstract: The cardiorespiratory response to exercise was measured in 27 children with functional single ventricle. All 27 patients had a significant reduction in exercise time, work performed, maximal exercise heart rate, maximal oxygen uptake and systemic arterial blood oxygen saturation. The reduction in exercise performance increased with increasing age of the patients. All patients ventilated excessively at rest and during exercise. This study documented the precise level of exercise intolerance in patients with functional single ventricle. The progressive deterioration in exercise performance with increasing patient age may lend credence to the concept that operation for physiologic correction of functional single ventricle should be considered during or before adolescence.
mesh_terms: D000293:Adolescent; D001794:Blood Pressure; D002648:Child; D004562:Electrocardiography; D005260:Female; D006330:Heart Defects, Congenital / Q000097:blood / Q000503:physiopathology; D006339:Heart Rate; D006352:Heart Ventricles / Q000002:abnormalities*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood / Q000502:physiology; D005082:Physical Exertion; D012119:Respiration; D014797:Vital Capacity
chemical_list: D006454:Hemoglobins; D010100:Oxygen