title: [Changes in hemodynamics during isometric loading in ischemic heart disease].
abstract: The hemodynamics and contractility of the myocardium were investigated in 38 men with coronary heart disease using maximal leg isometric load. It was shown that the systemic response to the isometric load in CHD patients unlike in normal subjects was mediated through increased total peripheral resistance rather than through an increase in myocardial contractility and stroke volume. The degree of these changes corresponded to the exercise tolerance as determined by bicycle ergometry. Leg isometric load is an accessible method for evaluating myocardial contractility in CHD which makes it possible to detect its disorders at the earliest stages in functional class I patients.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D003327:Coronary Disease / Q000503:physiopathology*; D005080:Exercise Test; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D009200:Myocardial Contraction; D013318:Stroke Volume; D014655:Vascular Resistance
vernacular_title: Izmeneniia gemodinamiki pri izometricheskoĭ nagruzke u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.