Cutaneous extramedullary hematopoiesis following splenectomy for idiopathic myelofibrosis.
A 50-year-old man with idiopathic myelofibrosis had development of extensive cutaneous extramedullary hematopoiesis after undergoing splenectomy. Treatment with hydroxyurea was not effective, but electron-beam irradiation controlled the cutaneous infiltration. This rare clinical manifestation of idiopathic myelofibrosis can be confused with cellulitis, and diagnosis depends upon biopsy.
D000368:Aged; D005260:Female; D006410:Hematopoiesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications* / Q000628:therapy; D012871:Skin Diseases / Q000209:etiology* / Q000532:radiotherapy; D013156:Splenectomy / Q000009:adverse effects*