Development of optimal drug administration strategies for cancer-chemotherapy in the framework of systems theory.
Design of Drug administration strategies for cancer chemotherapy is formulated as an optimization problem by considering both the healthy (normal) and tumor cell kinetics. The optimization problem is solved by using concepts of exponential stabilization and an algorithm for the solution of the above problem is presented.
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001854:Bone Marrow Cells; D002455:Cell Division; D003201:Computers; D006801:Humans; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology
D000970:Antineoplastic Agents