title: Expiratory flow limitation in large and small airways.
abstract: Obstructive airways diseases constitute 75% of all chronic respiratory diseases. This article briefly reviews the physlologic basis for flow limitation in large and small airways. Application of the physiologic principles described can lead to a better understanding of the normal mechanics of breathing and the various alterations resulting from diseases that limit airflow.
mesh_terms: D000403:Airway Resistance; D001980:Bronchi / Q000503:physiopathology; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D008448:Maximal Expiratory Flow Rate; D012123:Pulmonary Ventilation; D014109:Total Lung Capacity; D014797:Vital Capacity