The ultrastructure of mandibular condylar and rib cartilage from mice carrying the spondylo-metaphyseal chondrodysplasia (smc) gene.
The ultrastructural appearance of cartilage from a new mutant spondylo-metaphyseal chondrodysplasia (smc) is described. The matrix is abnormally rich in collagen fibres which often form a sheath around the chondrocytes. Collagen balls - spherical inclusions of collagen fibres - are a unique and characteristic feature of the matrix, and the chondrocytes contain large amounts of lipid.
D000130:Achondroplasia / Q000235:genetics*; D000818:Animals; D002356:Cartilage / Q000648:ultrastructure*; D003094:Collagen; D008335:Mandibular Condyle / Q000648:ultrastructure*; D051379:Mice; D008817:Mice, Mutant Strains; D008854:Microscopy, Electron; D012272:Ribs / Q000648:ultrastructure*
D003094:Collagen