Intracellular distribution of AMP deaminase in the pig thyroid gland.
AMP deaminase and adenosine deaminase activities were assayed in the subcellular fractions of pig thyroid gland. AMP deaminase is localized in the cytosolic fraction; however, this enzyme showed remarkable tendency to bind with the subcellular particulate fractions. Adenosine deaminase is also localized in the cytosolic fraction but in contradistinction to AMP deaminase, adenosine deaminase under the same experimental conditions has no tendency of binding to subcellular particulate fractions. The significance of AMP deaminase binding to subcellular particulate fractions is discussed.
D000659:AMP Deaminase / Q000378:metabolism*; D000243:Adenosine Deaminase / Q000378:metabolism; D000818:Animals; D008928:Mitochondria / Q000201:enzymology; D009709:Nucleotide Deaminases / Q000378:metabolism*; D013347:Subcellular Fractions / Q000201:enzymology; D013552:Swine; D013961:Thyroid Gland / Q000201:enzymology* / Q000648:ultrastructure
D009709:Nucleotide Deaminases; D000243:Adenosine Deaminase; D000659:AMP Deaminase