Spontaneous occurrence of synergistic bacterial gangrene following external pelvic irradiation.
A case of spontaneous synergistic bacterial gangrene occurring after external pelvic irradiation is presented in a 25-year-old woman with invasive cervical cancer. Treatment consisted of aggressive antibiotic therapy and extensive excision and debridement followed by split-thickness skin grafting. Both recovery and cosmetic results were satisfactory. The pathophysiology, predisposing factors, and treatment modalities are presented.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology*; D003646:Debridement; D005260:Female; D005734:Gangrene / Q000209:etiology*; D006801:Humans; D010388:Pelvis / Q000528:radiation effects*; D011247:Pregnancy; D011832:Radiation Injuries / Q000150:complications*; D011878:Radiotherapy / Q000009:adverse effects; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy
D000900:Anti-Bacterial Agents