Central haemodynamics in different stages of hypertension.
Central and systemic haemodynamics were investigated in 53 juvenile hypertensives (JH) and in 43 older hypertensives aged over 30 (OH). The cardiac index at rest was significantly higher in JH, stage I and II according to the WHO, than in OH, stage I and II. Hyperkinetic circulation was present in systolic as well as in systolic-diastolic hypertension. Peripheral vascular resistance was at rest in JH relatively elevated (in relation to the given cardiac output) and normalized during heavy muscular work. In OH, peripheral vascular resistance was elevated at rest, but did not normalize during exercise. Mean and end-diastolic pulmonary artery pressure are at rest and during exercise higher in OH, regardless of the stage of hypertension, while in JH they are normal. Mean and diastolic pulmonary artery pressure correlate with systolic pressure in systemic circulation at rest and during exercise both in JH and in OH. In OH, left heart filling pressure is during exercise higher in patients with signs of ischaemic heart disease.
D000293:Adolescent; D000328:Adult; D000375:Aging; D001775:Blood Circulation; D001794:Blood Pressure; D002302:Cardiac Output; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008875:Middle Aged; D005082:Physical Exertion; D011652:Pulmonary Circulation; D014655:Vascular Resistance