Bilateral sensorineural hearing loss from danazol therapy. A case report.
Danazol is a widely used drug that causes few major adverse reactions, most of which are rapidly reversible upon cessation of therapy. While the list of pharmacologic agents capable of causing hearing loss continues to grow, no published reports have ever implicated danazol. We treated a patient for bilateral sensorineural hearing loss due to danazol therapy. The hearing loss resolved promptly after withdrawal of the medication.
D000328:Adult; D003613:Danazol / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D034381:Hearing Loss / Q000139:chemically induced*; D006312:Hearing Loss, Bilateral / Q000139:chemically induced*; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced*; D006801:Humans; D011245:Pregnadienes / Q000009:adverse effects*
D011245:Pregnadienes; D003613:Danazol