Defective imino acid metabolism in hypoglycin-treated rats.
Oral administration of hypoglycin (5-6 mg/100 g body wt) to weanling rats produces, in addition to the well-recognized organic aciduria, pronounced iminoacidemia, hyperiminoacidura, and decreased activity of proline and hydroxyproline oxidases.
D000596:Amino Acids / Q000097:blood; D000818:Animals; D003521:Cyclopropanes / Q000494:pharmacology*; D007005:Hypoglycins / Q000494:pharmacology*; D007098:Imino Acids / Q000378:metabolism*; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000378:metabolism; D011394:Proline Oxidase / Q000378:metabolism; D051381:Rats
D000596:Amino Acids; D003521:Cyclopropanes; D007005:Hypoglycins; D007098:Imino Acids; D000587:Oxidoreductases Acting on CH-NH Group Donors; D011394:Proline Oxidase; C034575:hydroxyproline oxidase