Correlation of titer, preservation method, and storage of Mycoplasma gallisepticum F strain and the immune response in chickens.
The F strain of Mycoplasma gallisepticum (MG) was used either fresh or after lyophilization or freezing at -60 C to vaccinate young leghorn chickens. Vaccine stored either frozen or lyophilized for 22 months was also used. Each vaccine preparation was given at dosages ranging from 10(5) to 10(9) colony-forming units/ml. All dosage levels of MG significantly (P less than 0.05) reduced air-sac lesion scores after aerosol challenge with the R strain of MG at 6 weeks postvaccination, regardless of the method of vaccine preservation or storage.
D000400:Air Sacs; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D001428:Bacterial Vaccines / Q000276:immunology*; D002645:Chickens / Q000276:immunology*; D008297:Male; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000276:immunology / Q000662:veterinary; D011201:Poultry Diseases / Q000276:immunology; D011309:Preservation, Biological / Q000662:veterinary*; D012141:Respiratory Tract Infections / Q000473:pathology / Q000662:veterinary; D014611:Vaccination / Q000662:veterinary
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines