title: Involvement of the urinary bladder in systemic lupus erythematosus. A pathologic study.
abstract: Urinary bladder histologic changes were found in 16 of 35 necropsies from systemic lupus erythematosus (SLE) patients in whom adequate material was available for study. These included interstitial cystitis (n = 11), hemorrhage (n = 9), congestion (n = 7), vasculitis (n = 5), and perivenular infiltrate (n = 4). Abnormalities were found in only 5 of 30 control necropsies from patients with other diseases and in 4 of them these were hemorrhagic and chiefly due to indwelling catheters. SLE patients with histologic bladder changes were found to have pulmonary hemorrhage more frequently than those without. This suggests a common pathogenetic mechanism between interstitial cystitis and pulmonary hemorrhage in SLE.
mesh_terms: D000293:Adolescent; D000328:Adult; D001158:Arteries / Q000473:pathology; D003556:Cystitis / Q000150:complications; D005260:Female; D006470:Hemorrhage / Q000150:complications; D006801:Humans; D008171:Lung Diseases / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000473:pathology*; D008297:Male; D013158:Splenic Diseases / Q000150:complications / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology*