title: Effects of smoking on uteroplacental blood flow.
abstract: The effects of nicotine consumption on uteroplacental blood flow were studied in 20 pregnant women by means of placental blood flow measurements using indium-113m-transferrin. Smokers were found to have a higher rate of poor perfusion patterns than subjects of a control group. In addition, the number of cigarettes smoked daily was significantly correlated with the placental perfusion type. The mean birth weight of infants born by smokers was 250 g lower than in the control group. The results suggest that smoking during pregnancy may compromise uteroplacental blood flow and thus result in poor fetal development.
mesh_terms: D000328:Adult; D001724:Birth Weight / Q000187:drug effects; D001775:Blood Circulation / Q000187:drug effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009538:Nicotine / Q000009:adverse effects; D010920:Placenta; D010927:Placental Insufficiency / Q000209:etiology; D011247:Pregnancy; D012907:Smoking
chemical_list: D009538:Nicotine