title: Human low-molecular-mass kininogen. Amino-acid sequence of the light chain; homology with other protein sequences.
abstract: The complete amino acid sequence of the human low-molecular-mass kininogen light chain has been determined. The peptide chain contains 38 amino acid residues. In position 18 the half-cystine residue which forms the disulfide bridge to the heavy chain was found. Alignment of the present sequence with other kininogen light chain sequences indicated that the amino-terminal part of it is species-specific and the carboxy-terminal part is function-specific. Statistically significant internal homologies between various parts of the low-molecular-mass kininogen sequence as well as homologies between parts of the sequences of kininogen and ribonucleases were observed.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000990:Antithrombin III; D005075:Biological Evolution; D003201:Computers; D006801:Humans; D007704:Kininogens; D008970:Molecular Weight; D012260:Ribonucleases; D013045:Species Specificity
chemical_list: D007704:Kininogens; D000990:Antithrombin III; D012260:Ribonucleases