Evidence that activities of coagulation factors VII and X are linked to chromosome 13 (q34).
In 7 patients with various anomalies of chromosome 13 coagulation, studies were performed. A 50% decrease of activities of factor VII and X were noted only in cases with deletion of 13 (q34) which supports the hypothesis that they are linked to this region.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002901:Chromosomes, Human, 13-15; D005167:Factor VII / Q000235:genetics*; D005170:Factor X / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D014314:Trisomy
D005167:Factor VII; D005170:Factor X