Polarization of membrane glycoproteins during monocyte chemotaxis.
Distribution of membrane glycoproteins was studied in chemotactic monocytes using ferritin-conjugated lectins. The cells became polarized forming a pseudopodia at a leading head. Membrane glycoproteins were redistributed at the head. This phenomenon was not observed in chemokinetic or non-chemotactic cells suggesting that membrane glycoproteins may have a role in recognition of the chemoattractant.
D002633:Chemotaxis; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D009000:Monocytes / Q000276:immunology / Q000378:metabolism*
D006023:Glycoproteins; D008565:Membrane Proteins