Comparison of estrogen-induced hyperplasia to endometrial carcinoma.
Use of exogenous estrogens has been associated with endometrial cancer in a number of case-control studies. This observed association could be biased as a result of frequent misclassification of estrogen-induced hyperplasia as endometrial cancer. To evaluate this possibility, pathology slides from 233 patients with a hospital diagnosis of endometrial cancer were reviewed independently by two pathologists. The hospital diagnosis was confirmed by both pathologists in 86% of the cases, indicating that the misclassification of hyperplasia as carcinoma is uncommon.
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D004714:Endometrial Hyperplasia / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology*; D004967:Estrogens / Q000009:adverse effects*; D005260:Female; D006801:Humans; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology*
D004967:Estrogens