title: An acute intervention trial: the research nurse coordinator's role.
abstract: A multicenter randomized clinical trial can offer exciting and challenging opportunities to the clinical coordinators and other health professionals who participate in the conduct of a clinical trial at the clinical units. This article will address an acute intervention trial, the Multicenter Investigation of the Limitation of Infarct Size, and demonstrate some of the important responsibilities of the clinical unit research nurse coordinators in the conduct and operation of this trial.
mesh_terms: D000288:Administrative Personnel; D002986:Clinical Trials as Topic / Q000379:methods*; D004562:Electrocardiography; D005500:Follow-Up Studies; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000188:drug therapy*; D009718:Nurse Administrators; D011433:Propranolol / Q000627:therapeutic use; D011897:Random Allocation; D012107:Research Design
chemical_list: D011433:Propranolol; D006821:Hyaluronoglucosaminidase