Successful treatment of postoperative Candida endophthalmitis in an eye with an intraocular lens implant.
Candida endophthalmitis developed in the left eye of a 71-year-old man two months after he underwent extracapsular cataract extraction and intraocular lens implantation. The symptoms included decreased vision and redness but no pain. The discovery of the cause of the endophthalmitis was delayed because it was initially treated as a sterile postoperative inflammation. Vitrectomy with intracameral amphotericin B and treatment with topical and systemic amphotericin B and flucytosine led to resolution of the infection and a final visual acuity of 20/80. It was not necessary to remove the intraocular lens.
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy*; D002387:Cataract Extraction; D003596:Cytosine / Q000031:analogs & derivatives*; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D009916:Orbital Diseases / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy
D000666:Amphotericin B; D003596:Cytosine; D005437:Flucytosine