title: Distribution of the two mating types among Histoplasma capsulatum isolates obtained from an urban histoplasmosis outbreak.
abstract: The mating type distribution among the 28 Histoplasma capsulatum isolates obtained from the histoplasmosis outbreaks which occurred in Indianapolis in 1978-1979 and 1980-1981 was studied. The overall ratio of + and - types was 1:2.5. The isolates from disseminated patients showed a 1(+):1(-) ratio while the isolates from non-disseminated pulmonary cases showed a 1(+):4(-) ratio. The frequency of the + type in these outbreaks was three times higher than that of the previous study. This was due to an unusually high prevalence of the + type among the patients with disseminated histoplasmosis.
mesh_terms: D000818:Animals; D004196:Disease Outbreaks / Q000453:epidemiology; D006658:Histoplasma / Q000502:physiology*; D006660:Histoplasmosis / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D007196:Indiana; D008172:Lung Diseases, Fungal / Q000453:epidemiology / Q000382:microbiology*; D051379:Mice; D012098:Reproduction; D012988:Soil Microbiology; D014505:Urban Population