Circadian rhythms and temporal structure of the susceptibility to tonic-clonic seizures in the mouse.
A circadian paradigm of susceptibility to tonic-clonic convulsions was established for two strains of mice. This research dealt with rhythmometric methods for estimating the main circadian parameters characterizing the temporal structure of these behavioral phenomena. Such experiments provided a quantitative approach for studying some neurobiological mechanisms regulating the seizure susceptibility.
D000161:Acoustic Stimulation; D000818:Animals; D001921:Brain / Q000503:physiopathology; D002940:Circadian Rhythm; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains; D012894:Sleep Stages / Q000502:physiology