The effects of oestradiol-17 beta on the synthesis and modification of ribosomal proteins in the uterus of the immature rat.
The effects of oestrogen on the incorporation of newly-made ribosomal proteins into the ribosomes of the immature rat uterus has been investigated. Different newly-made proteins were shown to enter ribosomes at different rates and there was some evidence that the hormone exerted differential effects. Oestradiol also stimulated the phosphorylation of ribosomal protein S6 but the effect could be explained by hormone-induced changes in the precursor pools.
D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D007700:Kinetics; D051381:Rats; D012269:Ribosomal Proteins / Q000096:biosynthesis* / Q000302:isolation & purification; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism; D012741:Sexual Maturation; D014599:Uterus / Q000187:drug effects / Q000378:metabolism*
D012269:Ribosomal Proteins; D004958:Estradiol