[Correction of protein metabolism in myocardial infarction according to the results of radionuclide studies with 131-albumin during during treatment with a number of drugs (retabolyl, methyluracil, panangin, strophanthin) and combinations of them].
The effect of a series of drugs (retabolil, strophanthin, retabolil with strophanthin, retabolil with panangin , methyluracil with panangin ) on protein metabolism was investigated in 246 patients with acute myocardial infarction. Retabolil both alone and combined with panangin , and a methyluracil-- panangin combination were found to have anticatabolic and protein synthesizing effects. Strophanthin, when used in the acute period of myocardial infarction, contributes to an increase in the protein decay rate and a decrease in protein synthesis. When it is employed in combination with metabolism corrective agents (retabolil), the adverse effects of strophanthin mentioned above are eliminated.
D000328:Adult; D000368:Aged; D045930:Anabolic Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism; D009277:Nandrolone / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077603:Nandrolone Decanoate; D011195:Potassium Magnesium Aspartate / Q000008:administration & dosage; D012711:Serum Albumin, Radio-Iodinated / Q000378:metabolism*; D013328:Strophanthins / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage / Q000031:analogs & derivatives
D045930:Anabolic Agents; D012711:Serum Albumin, Radio-Iodinated; D013328:Strophanthins; D014498:Uracil; C008378:6-methyluracil; D009277:Nandrolone; D011195:Potassium Magnesium Aspartate; D000077603:Nandrolone Decanoate
Korrektsiia belkovogo metabolizma pri infarkter miodarda po dannym radionuklidnykh issledovaniĭ so 131I-albuminom pod vliianiem riada lekarstvennykh sredstv (retabolila, metiluratsila, panangina, strofantina) i ikh kombinatsiĭ.