Prostatic adenocarcinoma PC EW, a new human tumor line transplantable in nude mice.
A serially transplantable human prostatic carcinoma line, PC EW, has been developed through heterotransplantation of tumor tissue from a lymph node metastasis. PC EW is androgen dependent and is similar to the original tumor in terms of histological pattern, amounts of prostatic acid phosphatase secreted, and absence of a hormonally independent subline. This line is thus similar to PC 82, and we herein report the first results of comparative treatment trials conducted on PC EW.
D000135:Acid Phosphatase / Q000032:analysis; D000230:Adenocarcinoma / Q000473:pathology* / Q000648:ultrastructure; D000728:Androgens / Q000502:physiology; D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D002460:Cell Line; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009376:Neoplasms, Hormone-Dependent / Q000473:pathology / Q000648:ultrastructure; D011467:Prostate / Q000201:enzymology; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D013997:Time Factors
D000728:Androgens; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000135:Acid Phosphatase