title: [Estimation of the intensity of effect of cardenolides. 2: Algorithms for the estimation of the intensity of effect].
abstract: An algorithm worked on basis of quantitative relations between molecular-biologically defined effects and molecular-physical properties (see part 1) allows the effect estimation of concepted cardenolides before their synthesis. The empirical use of the developed equations for the estimation of molecular-biologically defined effect of compounds produces usable results and justifies therefore the proposed method, as well as it's shown by the experimental proof of estimated values of some cardenolides . An enlargement of the use of the algorithm for effect estimation seems to be successful.
mesh_terms: D002298:Cardenolides / Q000494:pharmacology*; D008433:Mathematics; D008954:Models, Biological; D008967:Molecular Biology; D013329:Structure-Activity Relationship
chemical_list: D002298:Cardenolides
vernacular_title: Abschätzung der Wirkstärke von Cardenoliden 2. Mitteilung: Algorithmus zur Abschätzung der Wirkstärke.