Abnormal pupillary function in third nerve regeneration (the pseudo-Argyll robertson pupil). A case report.
A case of congenital oculomotor paralysis demonstrating retraction of the upper lid and constriction of the pupil in response to eye movements is described. The pupil was found to be unresponsive to light, but to contract promptly on attempted ocular movements which involved motor neurons of the third nerve. As demonstrated by infrared pupillography, the duration of the constriction phase was found to be remarkably long. Also, very little hippus was noted during constriction. The findings are explained on basis of the 'misdirection' hypothesis according to which regenerating nerve fibres find a wrong path in the peripheral part of the damaged nerve.
D000293:Adolescent; D001763:Blepharoptosis / Q000209:etiology; D005260:Female; D006801:Humans; D009410:Nerve Degeneration; D009802:Oculomotor Nerve / Q000503:physiopathology*; D011680:Pupil / Q000503:physiopathology*; D013285:Strabismus / Q000209:etiology