title: A computer method for the comparison or the quantitative similarity between normal and abnormal collagen or between sequence data and experimental data.
abstract: In this paper, a method is described to correlate collagen structural data obtained by electron microscopy with chemical sequence data, or to compare two experimental sets of data. In this respect, collagen provides a valuable model system, firstly for studying the chemical basis of ultrastructure and the mechanisms of various treatments on a protein, and secondly for detecting and locating the alterations in collagen fibril structure produced by a collagen disorder.
mesh_terms: D000595:Amino Acid Sequence; D003094:Collagen; D003095:Collagen Diseases / Q000175:diagnosis*; D003201:Computers; D006801:Humans; D008854:Microscopy, Electron; D011487:Protein Conformation
chemical_list: D003094:Collagen