Exercise endurance-training alters vitamin E tissue levels and red-blood-cell hemolysis in rodents.
Muscle tissue levels of d1-alpha-tocopherol (vitamin E) were significantly lower in endurance-trained rats than in sedentary animals, whether the animals were fed on vitamin-E-deficient or control (vitamin-E-sufficient) diets. In vitamin-E-deficient rats, liver tissue levels of vitamin E were significantly lower in those that were endurance-trained than in those that were sedentary; this was not the case in control animals. In addition, for vitamin-E-deficient rats, the onset of red-blood-cell hemolysis in the sedentary animals occurred one week earlier than in the endurance-trained animals. Thus, it appears that training induces a protective effect against hemolysis despite vitamin E deficiency.
D000818:Animals; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology*; D005260:Female; D006461:Hemolysis / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D014810:Vitamin E / Q000378:metabolism* / Q000494:pharmacology; D014811:Vitamin E Deficiency / Q000503:physiopathology
D014810:Vitamin E