Immunological application and implication of pregnancy proteins.
Five pregnancy proteins which were discovered by immunological methods at our and two other laboratories were reviewed. These proteins have been purified, physico-chemically characterized, histologically localized and measured by immunological procedures in normal as well as certain abnormal pregnancies. They have been studied for their use as markers in the detection of certain tumors and for monitoring various abnormal pregnancies. Their possible functions as carriers for hormones and metals, in the coagulation system, and in immunological protection of the fetus from the maternal homograft rejection mechanism have also been investigated.
D000818:Animals; D005260:Female; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis* / Q000276:immunology / Q000502:physiology
D011257:Pregnancy Proteins