[Partial and combined effect of arterial hypertension and atherogenic shifts in blood lipid fractions on the incidence of ischemic heart disease].
The results of a purposeful epidemiologic study involving 3896 men and 1502 women aged 40-69 years from the same city district are presented. To correlate the prevalence of coronary heart disease (CHD) and the level of arterial pressure (AP), subjects with a low coefficient of atherogenicity (a ratio of pre-beta-and beta-lipoproteins to alpha-lipoproteins) from the first quartil (1360) and the fourth quartil (1325) were selected. The statistical distribution series was plotted for each decade of age in males and females differentially. The atherogenic composition of blood lipids was found to be the risk factor determining CHD incidence in males aged 40-59 and 50-59 and in females aged 50-59, whereas in subjects over 60 years of both sexes it was elevated AP levels. The presence of two leading CHD risk factors was associated with a considerable increase in CHD prevalence in all age groups of both sexes.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D003327:Coronary Disease / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D008875:Middle Aged
D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL
Partsial'noe i sochetannoe vliianie arterial'noĭ gipertenzii i aterogennogo sdviga lipidnykh fraktsiĭ krovi na chastotu ishemicheskoĭ bolezni serdtsa (populiatsionnoe issledovanie).