Effect of high perilymphatic potassium on brainstem evoked response audiometric thresholds.
The perilymphatic space of the cat cochlea was perfused with a solution containing a high potassium ion concentration. The auditory response threshold was monitored with brainstem evoked response audiometry. In the majority of animals the initial perfusion produced a reversible decline in response threshold. With repeat perfusions, there was a variable degree of non-reversible response decline leading ultimately to a total loss of the auditory response.
D000818:Animals; D001300:Audiometry, Evoked Response; D001309:Auditory Threshold / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology; D002415:Cats; D003051:Cochlea / Q000502:physiology*; D007761:Labyrinthine Fluids / Q000502:physiology*; D008564:Membrane Potentials; D051379:Mice; D010477:Perfusion; D010498:Perilymph / Q000502:physiology*; D011188:Potassium / Q000494:pharmacology / Q000502:physiology*
D011188:Potassium