title: [Interstitial irradiation of rectal carcinoma with rectal template].
abstract: Using Iridium-192 wires through a rectal template after Syed, interstitial brachytherapy was conducted in a patient with inoperable adenocarcinoma of the rectum. 67-year-old man with constipation and change in the stool caliber underwent external radiotherapy (4,000 cGy/4 W) to the whole pelvis including the perineum, followed by interstitial implant using a template, at the Department of Radiology, Osaka University Hospital. Marked tumor regression, marked circumferential fibrosis and a remarkable decline of CEA titers (pre-RT: 35.8 ng/ml, post-RT: 6.2 ng/ml) were observed until 7 months post-RT. The domestic production of Iridium-192 wires has made possible the integrated use of brachytherapy in the perineal region in Japan.
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D000368:Aged; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007495:Iridium / Q000627:therapeutic use*; D008297:Male; D011868:Radioisotopes / Q000627:therapeutic use*; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000532:radiotherapy*; D013698:Templates, Genetic
chemical_list: D011868:Radioisotopes; D007495:Iridium