Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin.
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001763:Blepharoptosis / Q000139:chemically induced*; D002395:Catecholamines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D007546:Isoquinolines / Q000494:pharmacology*; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D011758:Pyrroles / Q000494:pharmacology*; D012701:Serotonin / Q000378:metabolism; D013237:Stereoisomerism; D013747:Tetrabenazine
D000928:Antidepressive Agents; D002395:Catecholamines; D007546:Isoquinolines; D011758:Pyrroles; D012701:Serotonin; D004298:Dopamine; D009638:Norepinephrine; D013747:Tetrabenazine