title: Familial lichen amyloidosis.
abstract: In Japan, two cases of familial lichen amyloidosis were found in a mother and her son, who had a history of cutaneous amyloidosis in 11 adults of three family generations. HLA types in both patients were rather common ones among Japanese people. Topical application of dimethyl sulfoxide was effective in the mother but not in the son. Familial cutaneous amyloidosis (FCA) is a rare disease in Japan although nonfamilial-type is not uncommon. Possible parameters of FCA are discussed. The author recommends using "FCA" without "primary" as the name of the disease.
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000188:drug therapy / Q000235:genetics*; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012871:Skin Diseases / Q000188:drug therapy / Q000235:genetics*
chemical_list: D004121:Dimethyl Sulfoxide