Autotransplantation of bovine ocular squamous cell carcinoma and effects on primary tumor growth.
Autologous transplantation of ocular squamous cell carcinoma was done in 7 Hereford cows in 17 trials. Three preparations of tumor were used in orthotopic transplantation to 5 sites on the eye and eyelid. None of the transplants was successful. However, in 2 of 5 cows given autografts of a pure, viable tumor cell suspension, marked regression of the primary tumor was observed after transplantation.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000473:pathology*; D005134:Eye Neoplasms / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D009365:Neoplasm Regression, Spontaneous; D009368:Neoplasm Transplantation; D014182:Transplantation, Autologous