title: Influence of meal weight and caloric content on gastric emptying of meals in man.
abstract: This study was designed to assess the relative influence of meal weight and caloric content on gastric emptying of liquid and solid meals in man. A dual radioisotopic method which permits noninvasive and simultaneous measurement of liquid- and solid-phase emptying by external gamma camera techniques was employed. Nine healthy volunteer subjects ingested 50-, 300-, and 900-g lettuce and water meals adjusted to either 68, 208, or 633 kcal with added salad oil. The following observations were made: (1) absolute emptying rates (grams of solid food emptied from the stomach per minute) increased directly and significantly with meal weight; (2) increasing meal total caloric content significantly slowed solid food gastric emptying but did not overcome the enhancing effect of meal weight; and (3) liquid emptying rates were uninfluenced by meal total kcal amount.
mesh_terms: D002149:Energy Intake; D005069:Evaluation Studies as Topic; D005502:Food; D005746:Gastric Emptying; D006801:Humans; D066298:In Vitro Techniques; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D011897:Random Allocation; D013455:Sulfur; D013667:Technetium; D013671:Technetium Tc 99m Sulfur Colloid; D013997:Time Factors
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid; D013455:Sulfur; D013667:Technetium; D004369:Pentetic Acid