[Comparison of the structure and catabolism of rat thymus DNA exposed to tritium oxide and gamma-radiation in equal doses].
A decrease in DNA concentration and in the molecular mass of single-stranded DNA, an increase in the PDN content, and activation of acid DNAses in rat thymus were observed after a single administration of tritium oxide in a dose of 22 mBq/g (a cumulative dose of 7.8 Gy) and gamma-irradiation at a corresponding dose-rate and value of the cumulative dose. These changes were most pronounced during the period of dose accretion, i.e. during 14-30 days after the beginning of irradiation. The degree to which the indices under study varied from the controls was 2-3 times in rats given tritium oxide than in those exposed to gamma-irradiation.
D000818:Animals; D002588:Cesium Radioisotopes; D004247:DNA / Q000528:radiation effects*; D005720:Gamma Rays; D008297:Male; D011829:Radiation Dosage; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000528:radiation effects*; D013997:Time Factors; D014316:Tritium; D014867:Water
D002588:Cesium Radioisotopes; D014867:Water; D014316:Tritium; C033961:tritium oxide; D004247:DNA
Sravnenie struktury i katabolizma DNK vilochkovoĭ zhelezy krys pri deĭstvii okisi tritiia i gamma-oblucheniia v ravnykh dozakh.