Neonatal lupus erythematosus.
Three infants with neonatal lupus erythematosus (LE) had characteristic sharply marginated erythematous papules and plaques without congenital heart block. Two of the infants were definitely photosensitive, while the third infant's eruption began on a photoexposed area. All three infants and their mothers were positive for Ro Sjögren's syndrome A antigen (SSA) antibody. These three infants have additional evidence supporting the concept that transplacental passage of Ro (SSA) antibody is a serologic marker for neonatal LE.
D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006801:Humans; D007223:Infant; D008180:Lupus Erythematosus, Systemic / Q000151:congenital* / Q000276:immunology / Q000473:pathology; D008297:Male; D010787:Photosensitivity Disorders / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D012859:Sjogren's Syndrome / Q000276:immunology; D012867:Skin / Q000473:pathology
D001323:Autoantibodies