title: [Neuroendocrine sarcoidosis: a case].
abstract: The authors report a case of neuro-endocrine sarcoidosis, associating panhypopituitarism , diabetes insipidus, and involvement of the optic chiasma with behavioural changes, chronic meningitis and a diffuse pyramidal syndrome. The diagnosis was suggested by the presence of mediastinal lymphadenopathy and confirmed during a surgical procedure to conserve the optic nerves. The clinical course on corticosteroids was unfavourable because of iatrogenic cushing' syndrome and steroid dependence . It was not possible to withdraw steroids, even with the use of immunosuppressors (Methotrexate).
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002493:Central Nervous System Diseases / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D009897:Optic Chiasm / Q000473:pathology; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D010907:Pituitary Hormones / Q000097:blood; D011379:Prognosis; D012507:Sarcoidosis / Q000150:complications* / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D010907:Pituitary Hormones
vernacular_title: Sarcoïdose neuro-endocrinienne: un cas.