A zomepirac reaction mimicking ectopic pregnancy.
A case is presented of a 29-year old woman who developed sudden onset of abdominal pain, vomiting, near syncope, abdominal tenderness, profound hypotension, and a late menstrual period. The patient was in good health and her only medication was zomepirac for musculoskeletal discomfort. An exploratory mini-laparotomy was performed for the suspicion of a ruptured ectopic pregnancy, but no evidence of hemoperitoneum or of ectopic pregnancy was found. A subsequent pregnancy test was negative, and the episode was attributed to a zomepirac reaction. A review of zomepirac and zomepirac reactions is included.
D000328:Adult; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D010146:Pain / Q000139:chemically induced; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis*; D011758:Pyrroles / Q000009:adverse effects*; D012422:Rupture, Spontaneous / Q000175:diagnosis; D014046:Tolmetin / Q000009:adverse effects* / Q000031:analogs & derivatives
D011758:Pyrroles; C020549:zomepirac; D014046:Tolmetin