title: Depression and its pharmacological management.
abstract: Clinical factors of importance in the treatment of primary affective disorder with antidepressants are reviewed, and the selection of drugs is discussed on both clinical and biological grounds. Two recently validated neuro-endocrine tests used in the assessment of major depressive disorder are referred to, and research trends with regard to the neurobiology of these disorders are commented upon.
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans
chemical_list: D000928:Antidepressive Agents