title: [Treatment of ergotism].
abstract: Ergotism occurs in patients so disposed, particularly under ergotamine therapy for migraine. The principal signs are arterial spasms in the legs, or sometimes also the arms, which can lead to gangrene. Intravenous or intra-arterial infusion of sodium nitroprusside or nitroglycerine has proved the only reliably efficacious therapy. The best results have been obtained using nitroprusside: twelve cases are described here. By contrast, nonefficacious measures include, in particular, sympathetic blockade.
mesh_terms: D000328:Adult; D001132:Arm / Q000098:blood supply*; D004878:Ergotamine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005292:Ferricyanides / Q000627:therapeutic use*; D006801:Humans; D007263:Infusions, Parenteral; D007511:Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D009599:Nitroprusside / Q000627:therapeutic use*
chemical_list: D005292:Ferricyanides; D009599:Nitroprusside; D004878:Ergotamine
vernacular_title: Behandlung des Ergotismus.