Geographical variations in inborn errors of metabolism in Japan.
Using materials from a nationwide screening project on inborn errors of metabolism in Japan, the incidence of histidinemia, phenylketonuria, galactosemia and homocystinuria were found to be 140, 16, 14 and 7 in 1 million live births, respectively. Geographical variations were observed, especially in histidinemia, which are most likely due to chance.
D000592:Amino Acid Metabolism, Inborn Errors / Q000453:epidemiology; D005693:Galactosemias / Q000453:epidemiology; D006639:Histidine / Q000097:blood; D006801:Humans; D007564:Japan; D008375:Maple Syrup Urine Disease / Q000453:epidemiology; D008661:Metabolism, Inborn Errors / Q000453:epidemiology*; D010661:Phenylketonurias / Q000453:epidemiology
D006639:Histidine