title: Intrathecal dextrose to prevent seizures after metrizamide myelography in dogs.
abstract: Seizures are possible complications of metrizamide myelography. The protective effect (as measured by reduction in seizure incidence) of dextrose in solution with metrizamide was studied by conducting a double-blind trail. Fourteen dogs each had two myelograms at five- to 16-day intervals in a crossover study, while ten additional dogs each had a single myelogram. Metrizamide alone and metrizamide in dextrose were used for the myelograms. No significant protective effect of dextrose was found.
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D004285:Dogs; D004311:Double-Blind Method; D005947:Glucose / Q000008:administration & dosage*; D007278:Injections, Spinal; D008793:Metrizamide / Q000009:adverse effects*; D009192:Myelography / Q000662:veterinary*; D012640:Seizures / Q000517:prevention & control*
chemical_list: D005947:Glucose; D008793:Metrizamide