Squamous cell carcinoma and meningomyelocele.
A case of invasive squamous cell carcinoma arising in the skin overlying a large lumbar meningomyelocele is reported. This case is unique in that a chronic neurocutaneous fistula was not present. It is proposed that chronic irritation of the meningomyelocele was the primary factor in the pathogenesis of the cancer.
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D002557:Cerebrospinal Fluid Shunts; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D008591:Meningomyelocele / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*