title: Chromosome features of two retinoblastomas.
abstract: Giemsa-banded chromosomal analysis of two unilateral retinoblastoma tumors from unrelated patients with normal constitutional chromosomes revealed near-diploid karyotypes with multiple structural rearrangements. The two tumors shared aberrations of trisomy 1q, monosomy 16 and 17, and 21p+. Other aberrations were unique to each tumor. One tumor expressed a del(13) and trisomy 6p.
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D002904:Chromosomes, Human, 21-22 and Y; D005134:Eye Neoplasms / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D012175:Retinoblastoma / Q000235:genetics*; D014314:Trisomy