title: [Double-stranded DNA breaks and inactivation of mammalian cells in relation to the LET of the radiation--comparison between experiment and theory].
abstract: In experiments on Chinese hamster cells the survival curves and the yield of double-strand DNA breaks were determined after irradiation at different LET. The comparison of the experimental results and the survival curves calculated on the basis of Günter-Schultz's theory of radiation inactivation of cells has demonstrated that radiation-induced double-strand DNA breaks are responsible for the lethal effect of radiation on cells.
mesh_terms: D000512:Alpha Particles; D000818:Animals; D002244:Carbon; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000528:radiation effects*; D003903:Deuterium; D004735:Energy Transfer; D007477:Ions
chemical_list: D007477:Ions; D002244:Carbon; D004247:DNA; D003903:Deuterium
vernacular_title: Dvunitevye razryvy DNK i inaktivatsiia kletok mlekopitaiushchikh v zavisimosti ot LPE izlucheniĭ--sravnenie mezhdu éksperimentami i teorieĭ.