Toxicity and QSAR of chlorophenols on Lebistes reticulatus.
The 24-h toxicity of 20 substituted chlorophenols upon Lebistes reticulatus has been determined. The biological results have been tentatively connected with several of the following six parameters: logarithm of the octanol-water partition coefficient (log P); index of molecular connectivity (1 chi v); molecular refraction (RM); perimeter of the efficient section of the molecule (sigma D); constants of HAMMET (sigma); and melting point (F). A correlation is achieved using sigma D and sigma D2 with a correlation coefficient of 0.943.
D000818:Animals; D002733:Chlorophenols / Q000633:toxicity*; D003201:Computers; D005260:Female; D005399:Fishes; D007928:Lethal Dose 50; D008297:Male; D012044:Regression Analysis; D013329:Structure-Activity Relationship; D014873:Water Pollutants / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D002733:Chlorophenols; D014873:Water Pollutants; D014874:Water Pollutants, Chemical