title: Synthesis and properties of some 13-cis- and all-trans-retinamides.
abstract: Several 13-cis-retinamides were synthesized from 13-cis-retinoic acid via either 13-cis-retinoyl chloride or 13-cis-1-retinoylimidazole. All-trans-retinoylglycine was prepared from all-trans-retinoyl chloride and ethyl glycinate. Detailed procedures were developed for the preparation of other all-trans-retinamides on a large scale for studies of the chemoprevention of cancer.
mesh_terms: D000818:Animals; D006224:Cricetinae; D004355:Drug Stability; D004356:Drug Storage; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000517:prevention & control*; D009924:Organ Culture Techniques; D014212:Tretinoin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D014212:Tretinoin