Decreased sensitivity to tartrazine after aspirin desensitization in an asthmatic patient intolerant to both aspirin and tartrazine.
An aspirin- and tartrazine-sensitive asthmatic patient underwent a desensitization to the adverse effects of aspirin by oral aspirin challenges. After a month of daily aspirin ingestion, the patient's reactivity to tartrazine, tested by oral challenge, was observed to the blunted. This report suggests that desensitization to the adverse effects of aspirin might protect the patient against the adverse effects of tartrazine.
D000328:Adult; D001241:Aspirin / Q000009:adverse effects* / Q000276:immunology; D001249:Asthma / Q000276:immunology*; D001391:Azo Compounds / Q000009:adverse effects*; D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D012129:Respiratory Function Tests; D013645:Tartrazine / Q000009:adverse effects* / Q000276:immunology
D001391:Azo Compounds; D013645:Tartrazine; D001241:Aspirin