Dietary restriction retards age-related loss of gamma crystallins in the mouse lens.
The soluble crystallins in lenses from diet-restricted and control mice of diverse ages (2, 11, or 30 months) were studied by high-performance liquid chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Results obtained with both methods suggest that dietary restriction decelerates age-related loss of soluble gamma crystallins.
D000375:Aging; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003459:Crystallins / Q000032:analysis / Q000502:physiology*; D004032:Diet; D004591:Electrophoresis, Polyacrylamide Gel; D007908:Lens, Crystalline / Q000032:analysis / Q000502:physiology*; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D051381:Rats
D003459:Crystallins