Thrombocytosis: an acute-phase reactant, not an adverse reaction to the new beta-lactam antibiotics.
Thrombocytosis has been described as an adverse drug reaction in up to 30% of patients treated with new beta-lactam antibiotics. We evaluated 350 patients with acute noninfectious conditions and infectious diseases treated with a variety of new and old agents. Results indicate that thrombocytosis is an acute-phase reactant and not an adverse reaction to any antimicrobial agent.
D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D006801:Humans; D010976:Platelet Count; D012189:Retrospective Studies; D013922:Thrombocytosis / Q000139:chemically induced / Q000209:etiology*; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D047090:beta-Lactams