title: Disturbance of recent memory function in parkinsonian patients on anticholinergic therapy.
abstract: Disruption of cholinergic neurotransmission may result in memory impairment. In this study the anticholinergic drug, trihexyphenidyl, at low doses when administered chronically for one month to Parkinson disease patients caused a decrease in performance on recent but not immediate memory tests. Awareness of possible deterioration of memory function of parkinsonian patients on anticholinergic medication is necessary.
mesh_terms: D000368:Aged; D006801:Humans; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D010153:Paired-Associate Learning / Q000187:drug effects; D010300:Parkinson Disease / Q000188:drug therapy*; D014282:Trihexyphenidyl / Q000009:adverse effects* / Q000627:therapeutic use; D014706:Verbal Learning / Q000187:drug effects
chemical_list: D014282:Trihexyphenidyl