title: Anuloaortic ectasia: a clinical and echocardiographic study.
abstract: Twenty-six patients with an aortic root diameter greater than or equal to 3.7 cm by 2-dimensional echocardiography (2-D echo) were studied. Group I consisted of 14 patients (mean age 50 +/- 14 years) with idiopathic anuloaortic ectasia and group II consisted of 12 patients (mean age 60 +/- 12 years) with secondary causes of aortic root dilatation. Patients in group I had a significantly larger aortic root diameter at the level of the aortic valve (5.0 +/- 0.7 cm) and 2 cm above the aortic valve (5.3 +/- 1.2 cm) as assessed by echo than did patients in group II (4.1 +/- 0.3 and 4.4 +/- 0.4 cm, respectively, p less than 0.025). The diameter of descending thoracic aorta was slightly larger in patients in group II (3.1 +/- 0.8 vs 2.7 +/- 0.5 cm, difference not significant). Over a mean follow-up period of 18 months, in group I, aortic dissection developed in 3 patients and severe aortic regurgitation and congestive heart failure in 2; 7 patients had aortic root grafting, aortic valve replacement or both. The 3 patients in group I with aortic dissection had an aortic root diameter greater than or equal to 5.3 cm, but 4 asymptomatic patients also had a diameter greater than 5 cm. Only 1 patient in group II required surgery for aortic dissection. Thus, 2-D echo is useful in identifying and following high-risk patients with anuloaortic ectasia.
mesh_terms: D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000209:etiology; D001013:Aorta, Thoracic / Q000473:pathology / Q000503:physiopathology; D001014:Aortic Aneurysm / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D004108:Dilatation, Pathologic; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000627:therapeutic use
chemical_list: D011433:Propranolol