title: Neonatal myasthenia gravis. Anti-acetylcholine receptor antibodies in the amniotic fluid.
abstract: Neonatal myasthenia gravis (NMG) with mild arthrogryposis was observed at birth in the newborn infant of a myasthenic mother. Anti-acetylcholine receptor (anti-AChR) antibodies were present in the serum of both mother and child, in umbilical cord serum and in the amniotic fluid. The presence of anti-AChR antibodies in the amniotic fluid may be one of the causes of the NMG.
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis*; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D009157:Myasthenia Gravis / Q000276:immunology*; D011950:Receptors, Cholinergic / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D011950:Receptors, Cholinergic