Malignant mesothelioma in two pairs of siblings: is there a hereditary predisposing factor?
Two pairs of siblings with malignant pleural mesothelioma are reported. One sister and brother experienced slight household asbestos exposure during childhood. Two identical-twin brothers were occupationally exposed to asbestos for only 8 years. The occurrence of this rare neoplasm in 2 pairs of siblings indicates that a hereditary predisposing factor may exist.
D000368:Aged; D001194:Asbestos / Q000009:adverse effects; D004200:Diseases in Twins; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D012907:Smoking
D001194:Asbestos