title: Zinc ingestion and lipoprotein values in sedentary and endurance-trained men.
abstract: The finding that high doses (160 mg) of zinc lowered high-density lipoprotein-cholesterol prompted us to study the effect of low-dose zinc supplementation on lipoprotein values in sedentary and endurance-trained men. Twenty-one endurance-trained and 23 sedentary men received either placebo or 50 mg of zinc sulfate daily for eight weeks. Despite the fact that plasma zinc increased 15%, fasting plasma high-density-lipoprotein cholesterol, total cholesterol, low-density-lipoprotein cholesterol, and triglyceride levels did not change in response to zinc ingestion. We conclude that low-dose zinc supplementation does not affect lipid or lipoprotein values in either endurance-trained or sedentary men.
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004311:Double-Blind Method; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D010807:Physical Endurance; D010809:Physical Fitness; D014280:Triglycerides / Q000097:blood; D015032:Zinc / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol; D015032:Zinc