[The effect of extravascular administration of adrenaline solution into the carotid sinus on hemorrhage tolerance in anesthetized rabbits].
The haemorrhage tolerance in 31 with morphine-urethane solution narcotized rabbits were proved. By locale application of epinephrine at the carotid sinus in 19 rabbits the depressor afferent C-fibres were activated. The efferent sympathetic nerve activity of the kidney was clear decreased before and during the haemorrhage. The maximum of the cardiac frequency and the sympathetic activity in the epinephrine animals was measured when the volume depletion was about 10 percent higher. In comparison with the control rabbits the blood pressure at the end of haemorrhage was clear higher.
D000287:Administration, Topical; D000768:Anesthesia, General; D000818:Animals; D002346:Carotid Sinus / Q000187:drug effects*; D004837:Epinephrine / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006339:Heart Rate; D006470:Hemorrhage / Q000517:prevention & control*; D007668:Kidney / Q000187:drug effects / Q000294:innervation; D008297:Male; D010525:Peripheral Nerves / Q000187:drug effects; D011817:Rabbits; D012996:Solutions
D012996:Solutions; D004837:Epinephrine
Der Einfluss von extravasal am Sinus caroticus verabreichter Adrenalinlösung auf die Hämorrhagietoleranz narkotisierter Kaninchen.