title: Safety of fenbendazole use in cattle.
abstract: Fenbendazole (Panacur: Hoechst) has a low degree of toxicity, teratogenicity and adverse effects on the reproductive tract, and a high degree of safety in experimental animals. Acute, subacute and long-term toxicity trials in cattle given fenbendazole at dosages of up to 2 g/kg revealed no adverse effects. Studies of teratogenicity, effects on fertility, compatibility with other drugs, and safety for animal handlers had similarly negative results.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000662:veterinary; D000818:Animals; D001562:Benzimidazoles / Q000633:toxicity*; D002417:Cattle; D002418:Cattle Diseases / Q000139:chemically induced / Q000188:drug therapy*; D004285:Dogs; D004344:Drug Incompatibility; D004347:Drug Interactions; D005260:Female; D005273:Fenbendazole / Q000633:toxicity*; D005298:Fertility / Q000187:drug effects*; D006736:Horses; D008297:Male; D051379:Mice; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011817:Rabbits; D051381:Rats; D012756:Sheep
chemical_list: D001562:Benzimidazoles; D005273:Fenbendazole