title: [Effect of tetracycline hydrochloride on the development of the thymus structure in the rat].
abstract: Histological, electron microscopy and morphological methods were used to study the structure of the thymus of Wistar rats in the antenatal and early postnatal ontogenesis after administering to their mothers of the therapeutic doses of tetracycline hydrochloride at varying times of pregnancy (days 1-6, 8-13, 14-19). A study was also made of the alterations in the thymus of one-month-old rats exposed to the antibiotic prenatally in response to the administration of bacterial antigen.
mesh_terms: D000818:Animals; D005260:Female; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D011919:Rats, Inbred Strains; D013752:Tetracycline / Q000633:toxicity*; D013950:Thymus Gland / Q000187:drug effects* / Q000196:embryology / Q000254:growth & development; D013997:Time Factors; D014436:Typhoid-Paratyphoid Vaccines / Q000276:immunology
chemical_list: D014436:Typhoid-Paratyphoid Vaccines; D013752:Tetracycline
vernacular_title: Vliianie tetratsiklina gidrokhlorida na razvitie struktur vilochkovoĭ zhelezy u krys.