[Goldenhar syndrome. Discordance in monozygotic twins].
Child here described is a new-born male, the firstborn twin, who showed clinical-radiological manifestations compatible with an oculo-auriculo-vertebral syndrome or Goldenhar's syndrome. A comparison of chromosomes, identification of serological types and determination of antigens of histocompatibility (HLA) showed them to be similar in both twins, thus showing identity of monozygots . Of great importance in the anamnesis is a radiological study--cholecystography--which was practiced between 4th and 6th weeks of pregnancy. Differences shown and possible intervention of radiation as etiology mark the especial interest of this case.
D000016:Abnormalities, Radiation-Induced / Q000209:etiology; D000328:Adult; D002765:Cholecystography / Q000009:adverse effects; D004200:Diseases in Twins; D005260:Female; D006053:Goldenhar Syndrome / Q000209:etiology / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008342:Mandibulofacial Dysostosis / Q000235:genetics*; D011247:Pregnancy; D014430:Twins, Monozygotic
Síndrome de Goldenhar. Discordancia en gemelos monocigotos.