Furazolidone residues in chicken and swine tissues after feeding trials.
Broiler chickens and swine fed furazolidone in their diet were sacrificed, and samples of liver, kidney, skin/fat and muscle were harvested and analyzed for furazolidone residue. Chickens fed 200 g of furazolidone/ton of feed were withdrawn from treatment 21, 14, 7, 5, 3, or 0 days before slaughter. Birds withdrawn from medication more than 5 days prior to slaughter had no residues in any of the tissues sampled. One of the 12 birds in each of the 5 day and 3 day withdrawal groups had detectable residues in the skin/fat. Seven of the 12 birds in the 0 day withdrawal group had residues of less than 2 ppb in skin/fat samples. Chickens fed 400 g furazolidone/ton of feed were withdrawn from treatment 0 days before slaughter. Residues of 0.7 to 3.5 ppb were found in the skin of these birds; residues were not found in other tissues. Swine were fed 300 g furazolidone/ton of feed for 2 weeks or 150 g/ton for 5 weeks. They were withdrawn from treatment 10, 7, 5, 3, or 0 days before slaughter. Tissue samples taken from these swine did not contain detectable furazolidone residues.
D000273:Adipose Tissue / Q000378:metabolism; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001835:Body Weight; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D004032:Diet; D005241:Feathers / Q000032:analysis; D005664:Furazolidone / Q000032:analysis / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008460:Meat / Q000032:analysis*; D009132:Muscles / Q000378:metabolism; D013552:Swine; D013997:Time Factors
D005664:Furazolidone