title: Effects of enfenamic acid on renal electrolyte excretion in hypertensive patients.
abstract: Single and multiple doses of enfenamic acid were compared in hypertensive patients with those of hydrochlorothiazide using urinary output and electrolytes as parameters. With enfenamic acid, excretion of Na+, K+, and Cl- was significantly decreased in the multiple-dose study; after single doses, there was a significant decrease in the excretion of Na+ and Cl- only.
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D004573:Electrolytes / Q000652:urine*; D006801:Humans; D006852:Hydrochlorothiazide / Q000494:pharmacology; D006973:Hypertension / Q000652:urine*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine; D062367:ortho-Aminobenzoates / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D004573:Electrolytes; D062367:ortho-Aminobenzoates; C019126:enfenamic acid; D006852:Hydrochlorothiazide; D012964:Sodium; D011188:Potassium