[Cytogenetic and immunological changes in the peripheral blood of measles patients in the dynamics of the infectious process].
During the acute period of disease (2-5 days after infection) and later (one month after infection) the associative index of acrocentric chromosomes in T-lymphocytes was higher than in norm, whereas two weeks after infection it did not differ from that in norm. A correlation was found between the quantity of lymphocytes, having a certain number of associated acrocentric chromosomes, the quantity of sensibilized chromosomes, and the number of antibodies. Chromosome alterations in the lymphocytes of reconvalescents were recorded more often than at the start of the illness.
D000208:Acute Disease; D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D003289:Convalescence; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology / Q000648:ultrastructure*; D008457:Measles / Q000235:genetics* / Q000276:immunology; D008459:Measles virus / Q000276:immunology; D013997:Time Factors
D000914:Antibodies, Viral
Tsitogeneticheskie i immunologicheskie izmeneniia v perifericheskoĭ krovi u bol'nykh kor'iu v dinamike infektsionnogo protsessa.