The role of computed tomography in the detection of intrathoracic lymphoma.
Computed tomographic scanning of the chest in 100 patients with newly diagnosed malignant lymphoma detected mediastinal lymphadenopathy (39%) and parenchymal deposits (15%) with a significantly greater sensitivity and specificity than conventional radiological techniques. This principally affected the staging and treatment of patients with limited stage disease. The stage was changed in 10/61 patients (16%) with Stages I-III prior to CT scan and treatment was altered in 11/29 (38%) patients for whom radiation was the treatment of choice. Complete remissions as defined by CT scan have been more durable than those defined by CXR alone.
D000328:Adult; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D014056:Tomography, X-Ray; D014057:Tomography, X-Ray Computed