title: The effects of menopause and training on serum lipids.
abstract: Forty women were studied to determine the effect of training and menopause on serum levels of total cholesterol (Tc), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), and the ratio of HDL-C/LDL-C. Subjects were assigned to one of four groups: (a) premenopausal trained runners (Pre-T) (25-75 miles per week) (VO2max 44.82 ml/kg-1 X min-1) (N = 10); (b) premenopausal untrained who took part in no regular aerobic exercise (Pre-UT) (VO2max 28.60 ml/kg-1 X min-1) (N = 10); (c) postmenopausal trained runners (Post-T) (25-65 miles per week) (V02max 40.25 ml/kg-1 X min-1) (N = 10); (d) postmenopausal untrained who took part in no regular aerobic exercise (Post-UT) (VO2max 21.50 ml/kg-1 X min-1) (N = 10). None of the women smoked, were taking oral contraceptives, or any form of hormonal replacement. The postmenopausal women had all undergone natural menopause. Analysis of variance indicated: (a) no significant differences between Pre-T and Pre-UT in measures of Tc (188.04 mg/dl; 206.46 mg/dl) and HDL-C (73.2 mg/dl; 62.10 mg/dl) (P greater than 0.05) and a significant difference between Pre-T and Pre-UT in LDL-C (114.57 mg/dl; 144.57 mg/dl) and HDL-C/LDL-C (0.66; 0.44) (P less than 0.05); (b) no significant differences between Pre-T and Post-T for Tc, HDL-C, LDL-C, and HDL-C/LDL-C (P greater than 0.05); (c) significant differences between Pre-UT and Post-UT in Tc (206.46 mg/dl; 241.15 mg/dl), LDL-C (144.36 mg/dl; 184.85 mg/dl), and HDL-C/LDL-C (0.44; 0.32) (P less than 0.05), and no significant difference between these groups in HDL-C (P greater than 0.05); (d) no significant difference between Post-T and Post-UT in Tc (P greater than 0.05) and significant differences between these groups in measures of HDL-C (74.14 mg/dl; 55.54 mg/dl); LDL-C (141.45 mg/dl; 185.85 mg/dl), and HDL-C/LDL-C (0.57; 0.32) (P less than 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000328:Adult; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D008593:Menopause; D008875:Middle Aged; D010806:Physical Education and Training; D012420:Running
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D002784:Cholesterol