Vitamin B6 intake and plasma pyridoxal phosphate concentrations in the first 2 weeks of life.
Plasma pyridoxal phosphate concentrations were measured in 178 hospitalised neonates. A reference interval for neonates less than 7 day old, of 25 to 78 nmol/l has been established. Vitamin B6 intakes did not correlate well with plasma pyridoxal concentrations despite 26 neonates receiving less than the Recommended Allowance (0.3 mg/d) and 19 receiving amounts below which convulsions have been associated (0.1 mg/d). Ten percent of those infants fed breast milk had plasma pyridoxal phosphate levels below the reference interval compared with only 4% of those fed milk formulae. Breast milk from mothers with babies less than 14 days old had a total vitamin B6 contents reference interval of 5 to 40 micrograms/l. Twenty percent of breast milk samples had virtually no vitamin B6 detected.
D001663:Bilirubin / Q000097:blood; D005260:Female; D006801:Humans; D007225:Infant Food / Q000032:analysis; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D007567:Jaundice, Neonatal / Q000097:blood; D008297:Male; D008895:Milk, Human / Q000032:analysis; D011732:Pyridoxal Phosphate / Q000097:blood*; D011736:Pyridoxine / Q000008:administration & dosage* / Q000032:analysis; D012016:Reference Values; D012640:Seizures / Q000097:blood / Q000188:drug therapy
D011732:Pyridoxal Phosphate; D011736:Pyridoxine; D001663:Bilirubin