title: Vertical transmission of Bacillus piliformis infection (Tyzzer's disease) in a guinea pig: case report.
abstract: Tyzzer's disease (Bacillus piliformis infection) was diagnosed at necropsy in a hysterectomy-derived, gnotobiotically reared guinea pig. This is the first description of spontaneous vertical, presumably transplacental, transmission of B. piliformis infection. Subsequent horizontal transmission of the infection was concluded from the presence of specific anti-B. piliformis antibodies in the sera from guinea pigs originating from different litters but reared in the same isolator.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D000907:Antibodies, Bacterial / Q000032:analysis; D001407:Bacillus / Q000276:immunology / Q000302:isolation & purification; D001424:Bacterial Infections / Q000175:diagnosis / Q000635:transmission / Q000662:veterinary*; D005260:Female; D006168:Guinea Pigs; D008099:Liver / Q000382:microbiology / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis / Q000635:transmission / Q000662:veterinary*; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000635:transmission / Q000662:veterinary*; D012376:Rodent Diseases / Q000175:diagnosis / Q000635:transmission*
chemical_list: D000907:Antibodies, Bacterial