Isotype IgE class-specific suppression in the Biozzi 'High' and 'Low' lines of mice.
The suppression of the production of IgE antibody was investigated with the Biozzi 'High' and 'Low' lines of mice. Using the adoptive transfer method formerly experimented with SJL mice (donor I immunized with 0.2 microgram dinitrophenylated ovalbumin, donor II hyperimmunized with 10 micrograms keyhole limpet hemocyanin and donor III being unimmunized mice) IgE suppression was observed in recipients irradiated with 600 R only with the 'Low' line.
D000818:Animals; D007108:Immune Tolerance; D007116:Immunization, Passive; D007126:Immunoglobulin Allotypes; D007073:Immunoglobulin E / Q000235:genetics* / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*
D007126:Immunoglobulin Allotypes; D007073:Immunoglobulin E