[Role of formalin in the occurrence of sclerosing lesions of the bile ducts. Experimental approach in dogs. Apropos of 3 clinical cases].
The authors experimentally reproduced in dogs, sclerosing lesions of biliary tract similar to those that they noticed in clinical practice, after the use of a formalin solution for sterilization of the hydatid cysts of the liver. These lesions have been found with formalin solutions more concentrated than those used in surgical treatment of liver echinococcosis. Nevertheless, even with the use of lower concentrated solution in every case, inflammatory scars are produced in the liver and the biliary tract with persist several months after the formalin injection consequently, the authors recommend to forsake the abandonment of this product for surgical treatment of hydatid cyst.
D000328:Adult; D000368:Aged; D000818:Animals; D001649:Bile Duct Diseases / Q000139:chemically induced*; D001652:Bile Ducts / Q000473:pathology*; D004195:Disease Models, Animal; D004285:Dogs; D004444:Echinococcosis, Hepatic / Q000601:surgery*; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D012598:Sclerosis
D005557:Formaldehyde
Le rôle du formol dans la survenue de lésions sclérosantes des voies biliaires. Approche expérimentale chez le chien. A propos de 3 observations cliniques.