Further evidence from tryptic peptide analysis for heterogeneity among type D retroviruses.
Tryptic peptide analyses were performed on the major internal structural proteins of type D retroviruses isolated originally from subhuman primate species (MPMV, SMRV, LV) and from permanent human cell lines (HeLaV, HEp-2V, PMFV). The p25 peptide maps of MPMV, LV, PMFV and HEp-2V were very similar but showed a striking dissimilarity to the p25 map of HeLaV and the p35 map of SMRV. All type D viruses included in this study could be distinguished by peptide maps of at least two of their three low-molecular-weight proteins p10, p12 and p15. These studies further demonstrate the heterogeneity among type D retroviruses.
D002460:Cell Line; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D010446:Peptide Fragments / Q000032:analysis*; D010761:Phosphorus Radioisotopes; D012190:Retroviridae / Q000032:analysis*; D012208:Rhabdomyosarcoma; D014357:Trypsin; D014764:Viral Proteins / Q000302:isolation & purification*; D015678:Viral Structural Proteins
D010446:Peptide Fragments; D010761:Phosphorus Radioisotopes; D014764:Viral Proteins; D015678:Viral Structural Proteins; D014357:Trypsin