Morphometric studies on the age changes of autofluorescent granules and lysosomes in the epithelial cells of rat kidneys.
Morphometric analysis of the lysosomal system in the proximal convoluted tubules of the kidney of rats of different ages was studied, with special regard to the accumulation of autofluorescent pigment in the epithelial cells. After maturity, the lysosomal amount in the epithelial cells was significantly increased in the 25-29-month-old group; however, the amount of autofluorescent pigment granules was not significantly increased.
D000375:Aging; D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D007668:Kidney / Q000033:anatomy & histology*; D008062:Lipofuscin / Q000378:metabolism*; D008247:Lysosomes / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D010860:Pigments, Biological / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D008062:Lipofuscin; D010860:Pigments, Biological