title: Breath hydrogen test in infants and children with blind loop syndrome.
abstract: Breath hydrogen production after oral lactose loading was examined in infants and children with stagnant loop syndrome, blind loop syndrome, or both. All six infants under 3 years of age had bacteriological evidence of small intestinal colonization. The characteristics of the breath hydrogen test in this syndrome are: (a) extremely high basal excretion of breath hydrogen (after overnight fasting); (b) an earlier and greater breath hydrogen value (0.293 +/- 0.201 ml/min/m2: mean +/- SD) after oral lactose administration than formed in lactose malabsorption alone (0.050 +/- 0.041 ml/min/m2); and (c) the observation of a sustained hydrogen rise over several hours. This investigation demonstrated that the breath hydrogen test is a promising and noninvasive tool for diagnosing blind (or stagnant) loop syndrome.
mesh_terms: D001765:Blind Loop Syndrome / Q000175:diagnosis* / Q000628:therapy; D001944:Breath Tests / Q000379:methods*; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006859:Hydrogen / Q000032:analysis*; D007223:Infant; D007785:Lactose; D008297:Male; D011184:Postoperative Period; D013997:Time Factors
chemical_list: D006859:Hydrogen; D007785:Lactose