title: Cytoplasmic transfer of oligomycin resistance during protoplast fusion of Saccharomycopsis lipolytica.
abstract: Mitotic segregation of oligomycin resistance and oligomycin sensitivity was observed among the prototrophic progeny of protoplast fusion between drug-resistant and drug-sensitive complementary auxotrophs of Saccharomycopsis lipolytica. The transfer of oligomycin resistance by protoplast fusion without karyogamy suggests a cytoplasmic inheritance of this drug resistance determinant.
mesh_terms: D001203:Ascomycota / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D005796:Genes; D005821:Genetic Techniques; D009154:Mutation; D009840:Oligomycins / Q000494:pharmacology*; D011523:Protoplasts / Q000502:physiology; D012442:Saccharomycopsis / Q000187:drug effects* / Q000235:genetics
chemical_list: D009840:Oligomycins