Pseudovitreous fluid based on sodium carboxymethylcellulose.
Various materials have been suggested for vitreous replacement following vitreoretinal surgery. We studied the use of a viscous physiologic solution based on sodium carboxymethylcellulose, a synthetic polymer structurally similar to hyaluronic acid. Following vitrectomy this pseudovitreal fluid was injected into the vitreous cavity of rabbits. The material appeared to be well tolerated during a six-month observation period.
D000818:Animals; D002266:Carboxymethylcellulose Sodium / Q000494:pharmacology / Q000592:standards*; D004596:Electroretinography; D008747:Methylcellulose / Q000031:analogs & derivatives*; D011817:Rabbits; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000187:drug effects*
D008747:Methylcellulose; D002266:Carboxymethylcellulose Sodium