Translocation t(3;17)(q26;q22): a marker of acute disease in myeloproliferative disorders?
A new reciprocal translocation, t(3;17)(q26;q22), has been observed in three patients with myeloproliferative disease. The t(3;17) seems to be associated with acceleration of the disorder, thus adding further evidence to a relationship between 17q22 rearrangements and acute myeloproliferation .
D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D005500:Follow-Up Studies; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000175:diagnosis / Q000235:genetics*; D014178:Translocation, Genetic