Photoprotective adaptation. Some quantitative aspects.
The magnitude and time course of UV radiation-induced photoprotection was investigated in fair-skinned volunteers. Resistance to sunburn was evident three days following single exposures to UV-B, reached a maximum by seven days, and declined gradually over a period of 30 to 40 days. Both the magnitude and time course of UV radiation-induced photoprotection were dose related. The maximal mean protection factor following an exposure to 2 minimal erythemal doses was 4.2. The present findings, along with earlier studies, suggest that there are pronounced spectral differences with regard to the induction of photoprotective adaptation and that UV-B wavelengths are the most effective.
D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D008297:Male; D011829:Radiation Dosage; D012867:Skin / Q000528:radiation effects*; D012879:Skin Physiological Phenomena; D013471:Sunburn / Q000517:prevention & control; D013472:Sunlight / Q000009:adverse effects; D014466:Ultraviolet Rays / Q000009:adverse effects*