Effect of atropine sulfate on tear production in the cat when used with ketamine hydrochloride and acetylpromazine maleate.
Schirmer I tear tests were done on 10 cats before and during anesthesia induced with ketamine hydrochloride in combination with acetylpromazine maleate, with and without atropine sulfate as a preanesthetic agent. Use of atropine sulfate alone decreased tear production from a mean base-line value of 16.9 +/- 3.7 mm/min to 8.2 +/- 4.9 mm/min, 10 minutes after its subcutaneous administration. Tear production continued to decrease from 8.2 +/- 4.9 mm/min to a mean of 2.3 +/- 2.5 mm/min at 30 minutes after the administration of the ketamine hydrochloride and acetylpromazine maleate combination.
D000075:Acepromazine; D000758:Anesthesia / Q000662:veterinary*; D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D002415:Cats / Q000502:physiology*; D005260:Female; D007649:Ketamine; D008297:Male; D011292:Premedication / Q000662:veterinary; D013666:Tears / Q000378:metabolism*
D000075:Acepromazine; D007649:Ketamine; D001285:Atropine