title: Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.
abstract: Intracranial pressure and cerebrospinal fluid hypoxanthine and xanthine concentrations were measured in hydrocephalic children with suspected raised intracranial pressure. There was a highly significant correlation between intracranial pressure and cerebrospinal fluid hypoxanthine and xanthine levels.
mesh_terms: D000293:Adolescent; D001928:Brain Diseases, Metabolic / Q000134:cerebrospinal fluid*; D002545:Brain Ischemia / Q000134:cerebrospinal fluid; D002648:Child; D002675:Child, Preschool; D004734:Energy Metabolism; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid*; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000134:cerebrospinal fluid*; D007223:Infant; D007427:Intracranial Pressure; D012895:Sleep, REM / Q000502:physiology; D019820:Xanthine; D014970:Xanthines / Q000134:cerebrospinal fluid*
chemical_list: D007042:Hypoxanthines; D014970:Xanthines; D019820:Xanthine; D019271:Hypoxanthine