Effects of gamma radiation on pig platelet function.
The effects of gamma radiation (60Co source) on pig platelet aggregation, protein secretion, and malonyldialdehyde (MDA) formation were studied. It was observed that gamma radiation (0.1-1 kGy ) modified platelet function, i.e., inhibited platelet aggregation and secretion with concomitant lipid peroxidation expressed by increased amounts of malonyldialdehyde. MDA production in irradiated platelets was dependent on the dose of gamma radiation.
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism / Q000528:radiation effects*; D002462:Cell Membrane / Q000032:analysis; D005720:Gamma Rays / Q000009:adverse effects; D010974:Platelet Aggregation / Q000528:radiation effects; D013552:Swine; D013917:Thrombin / Q000494:pharmacology
D013917:Thrombin