[Composition of the polypeptides participating in orthograde axonal transport in the nerve elements of the caudal mesenteric ganglion of the cat].
Composition of the polypeptides translocated by the axonal transport in the lumbar splanchnic and hypogastric nerves before and after total section of these nerves was studied in the model of the inferior mesenteric ganglion with pre- and postganglionic nerve trunks. The data obtained suggest presence of the orthograde axonal transport of specific proteins associated with the nerve fibre growth along the axons of afferent neurons whose bodies are localized in the inferior mesenteric ganglion, as well as along efferent fibres with trophic centers situated in the ganglion. Axonal transport of the polypeptide with molecular weight 29.000 Dalton unidentified in other nerve structures was shown to occur along the afferent fibers.
D000818:Animals; D001369:Axons / Q000187:drug effects / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002415:Cats; D003078:Colchicine / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D005728:Ganglia, Sympathetic / Q000187:drug effects / Q000378:metabolism*; D007001:Hypogastric Plexus / Q000187:drug effects / Q000378:metabolism; D066298:In Vitro Techniques; D009475:Neurons, Afferent / Q000187:drug effects / Q000378:metabolism*; D009476:Neurons, Efferent / Q000187:drug effects / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D010455:Peptides / Q000032:analysis / Q000378:metabolism*; D013153:Splanchnic Nerves / Q000187:drug effects / Q000378:metabolism; D014747:Vinblastine / Q000494:pharmacology
D010455:Peptides; D014747:Vinblastine; D003078:Colchicine; D009638:Norepinephrine
Sostav polipeptidov, uchastvuiushchikh v ortogradnom aksonal'nom transporte v nervnykh élementov kaudal'nogo bryzheechnogo ganglia koshki.