title: [Derivatives of lithocholic acid with antibacterial and antifungal activity. IV].
abstract: A series of N-substituted amides of litocholic acid and some N-substituted derivatives of 3 alpha-hydroxy-24-amino-5 beta- cholane were prepared and their in vitro antibacterial and antifungal activity determined against a variety of gram-positive and gram-negative strains and two kinds of mycetes . Some of the tested compounds showed an interesting activity against gram-positive strains and mycetes .
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis*; D008095:Lithocholic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D008095:Lithocholic Acid
vernacular_title: Derivati dell'acido litocolico ad attività antibatterica ed antifungina. Nota IV.