Disseminated BCG infection in a child with chronic granulomatous disease. A case report.
A patient suffering from chronic granulomatous disease (then undiagnosed) developed progressive BCG infection from the age of 4 months. At about the age of 10 months his parents instituted legal action against the State on the grounds that their consent for BCG vaccination had been given when they were uninformed; approximately 4 months later the underlying immune defect was established. Complications of BCG vaccination are rare. The various factors that may be involved in their aetiology are outlined, and the association of chronic granulomatous disease and progressive BCG infection is briefly discussed.
D001500:BCG Vaccine / Q000009:adverse effects*; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000473:pathology; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009164:Mycobacterium Infections / Q000209:etiology*
D001500:BCG Vaccine