The effect of feeding diets containing avoparcin and monensin on the occurrence of Salmonella in caecum and liver in experimentally infected chickens.
In two experiments (Experiments A and B) chickens experimentally infected with S. infantis at 7 days of age and fed diets containing both avoparcin (10 ppm) and monensin (90 ppm) showed a higher frequency of Salmonella-positive livers and higher caecal counts of Salmonella 1 and 2 weeks after challenge than similarly infected chickens fed only avoparcin (10 ppm). The results may indicate a synergistic action between the two drugs on the ability of chickens to withstand Salmonella infections.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002432:Cecum / Q000382:microbiology*; D002645:Chickens / Q000382:microbiology*; D005260:Female; D005503:Food Additives; D005663:Furans / Q000494:pharmacology*; D006020:Glycopeptides / Q000494:pharmacology; D008099:Liver / Q000382:microbiology*; D008297:Male; D008985:Monensin / Q000494:pharmacology*; D011201:Poultry Diseases / Q000382:microbiology*; D012475:Salmonella / Q000187:drug effects; D012481:Salmonella Infections, Animal / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D005503:Food Additives; D005663:Furans; D006020:Glycopeptides; D008985:Monensin; C016249:avoparcin