Surface reaction of Leishmania. III. Ulex europaeus II lectin affinity for excreted factor (EF) serotype A strains.
Eukaryotic parasites, including species of Leishmania, acquire or synthesize carbohydrate moieties similar to human blood group antigens. Leishmanial strains separate into three serotypes: A, B and AB. All strains containing the A component are agglutinated by Ulex europaeus lectin. Inhibition by haptene sugar suggests that a Ulex II-like receptor is involved. Organic solvents, but not protease treatment, remove its reactivity, suggesting that the receptor is a glycolipid.
D000372:Agglutination Tests; D000818:Animals; D000915:Antibody Affinity; D000918:Antibody Specificity; D001789:Blood Group Antigens / Q000276:immunology; D002241:Carbohydrates / Q000494:pharmacology; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D037102:Lectins / Q000276:immunology*; D007891:Leishmania / Q000145:classification* / Q000276:immunology; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000032:analysis; D012703:Serotyping
D001789:Blood Group Antigens; D002241:Carbohydrates; D037102:Lectins; D037121:Plant Lectins; D011975:Receptors, Mitogen; C036850:Ulex europaeus lectins