title: Models of cell interaction based on differential adhesion.
abstract: Recent efforts to model the mechanical interaction of aggregates of biological cells are reviewed. Differential adhesion is discussed as a means of creating a field of stress equivalent to tension elements at interfaces between unlike cell types. Several numerical algorithms are described and applied to shortening and folding of cell sheets, three-dimensional monolayers, and two-dimensional cell aggregates.
mesh_terms: D001696:Biomechanical Phenomena; D002448:Cell Adhesion; D002450:Cell Communication; D008433:Mathematics; D008954:Models, Biological