title: In vitro effect of hyaluronate on lysosomal enzyme activities in the bovine ciliary body and iris.
abstract: The effect of hyaluronate on lysosomal enzyme activities in bovine ciliary body and iris was studied in vitro. Hyaluronates from both the human umbilical cord and bovine vitreous inhibited the activities of cathepsin B and acid phosphatase. Cathepsin D, beta-N-acetyl-glucosaminidase, beta-D-glucuronidase and alpha-L-fucosidase activities were not affected by the hyaluronate.
mesh_terms: D000135:Acid Phosphatase / Q000037:antagonists & inhibitors; D000818:Animals; D002403:Cathepsins / Q000037:antagonists & inhibitors; D002417:Cattle; D002924:Ciliary Body / Q000187:drug effects / Q000201:enzymology*; D006820:Hyaluronic Acid / Q000494:pharmacology*; D066298:In Vitro Techniques; D007498:Iris / Q000187:drug effects / Q000201:enzymology*; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D014470:Umbilical Cord; D014822:Vitreous Body
chemical_list: D006820:Hyaluronic Acid; D000135:Acid Phosphatase; D002403:Cathepsins