Long-term amiodarone therapy: a cause of increased hepatic attenuation on CT.
Approximately 40% of the anti-arrhythmic drug, amiodarone, consists of iodine. During long-term therapy both the drug and its major metabolite, desethylamiodarone, are deposited in the liver. CT scans of patients receiving such therapy demonstrated increased hepatic attenuation.
D000368:Aged; D000638:Amiodarone / Q000378:metabolism / Q000627:therapeutic use*; D001572:Benzofurans / Q000627:therapeutic use*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000378:metabolism; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D001572:Benzofurans; D000638:Amiodarone