The painful wrist.
Almost certainly, any condition producing pain in the wrist will interfere with the use of the hand. This in turn can cause impaired function of the whole of the limb.
D001172:Arthritis, Rheumatoid / Q000503:physiopathology; D006801:Humans; D010146:Pain / Q000503:physiopathology*; D013581:Synovial Cyst / Q000503:physiopathology; D013717:Tenosynovitis / Q000503:physiopathology; D014953:Wrist; D014954:Wrist Injuries / Q000503:physiopathology; D014955:Wrist Joint / Q000503:physiopathology*