Felty's syndrome associated with high levels of IgA rheumatoid factor.
A 64-year-old woman with rheumatoid arthritis developed Felty's syndrome. Her serum contained large amounts of IgA rheumatoid factor (RF) but insignificant levels of IgM-RF and IgG-RF. It is postulated that the high levels of IgA-RF may have contributed to the neutropenia.
D004797:Enzyme-Linked Immunosorbent Assay; D005258:Felty Syndrome / Q000150:complications / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008875:Middle Aged; D009503:Neutropenia / Q000209:etiology; D012217:Rheumatoid Factor / Q000032:analysis*
D007070:Immunoglobulin A; D012217:Rheumatoid Factor