[Evaluation by delayed hypersensitivity immune reactions of the infectious risk in digestive surgery. Experience with 1300 cases].
Immunity reactivity in 1300 patients during digestive surgery and intensive care was determined by delayed hypersensitivity cutaneous tests. A significant correlation (p less than 0.0001) existed between anergy, the risk of infection and mortality from sepsis (36,5% vs 1,3%) and during sequential changes in test results with prognosis (59% vs 2,9%) (p less than 0.001). Factors capable of influencing immune responses are: neoplasm (296 patients); poor nutrition (114 patients); infections (308 patients). The risk of infection and improvement in prognosis was obtained by control of anergy by means of a high protein-high calorie diet (57 cases), and by attacking infection and stimulating immunity (190 patients) by BCG followed by DTC. The use of disposable, preloaded multiple-puncture equipment, that is simple and rapid in use and in interpretation, provides a current reliable means for evaluating the risk of infection in digestive surgery.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004066:Digestive System Diseases / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007109:Immunity; D008297:Male; D008875:Middle Aged; D012306:Risk; D012882:Skin Tests; D013530:Surgical Wound Infection / Q000276:immunology / Q000517:prevention & control*
Evaluation par les réactions immunitaires d'hypersensibilité retardée du risque infectieux en chirurgie digestive. Expérience de 1300 cas.