Counterimmunoelectrophoresis in the rapid diagnosis of bacterial meningitis.
Cerebrospinal fluid from patients with clinically diagnosed meningitis was tested for meningococcal, pneumococcal, streptococcal Group B and Haemophilus influenzae antigens by counterimmunoelectrophoresis. Antigens were rapidly identified and the results compared favourably with that of bacteriological culture. In the case of pneumococcal meningitis counterimmunoelectrophoresis proved to be more sensitive than culture. The procedure was shown to be sensitive, specific, rapid and easily performed.
D000208:Acute Disease; D001424:Bacterial Infections / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D003378:Counterimmunoelectrophoresis; D006801:Humans; D007122:Immunoelectrophoresis; D008581:Meningitis / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D008583:Meningitis, Haemophilus / Q000134:cerebrospinal fluid / Q000175:diagnosis; D008585:Meningitis, Meningococcal / Q000134:cerebrospinal fluid / Q000175:diagnosis; D008586:Meningitis, Pneumococcal / Q000134:cerebrospinal fluid / Q000175:diagnosis