title: Observations on the use of glyceryl guaiacolate as an adjunct to general anaesthesia in horses.
abstract: Twenty-one horses undergoing clinical surgery and diagnostic procedures received 15% glyceryl guaiacolate followed by a rapid intravenous injection of a thiobarbiturate for induction of anaesthesia. Premedication was with atropine and acepromazine. Induction was smooth and free from problems apart from transient apnoea in some horses. Maintenance of anaesthesia was with oxygen and halothane administered by means of a closed circle system with soda-lime absorber and with the vaporiser out of circuit. During the period immediately following induction, the heart rate increased and the respiratory rate fell. Blood gas estimations were carried out on 6 horses during anaesthesia. These horses showed respiratory acidosis. Arterial blood oxygen tension values were above those reported in conscious horses. Use of glyceryl guaiacolate in this way provides a safe induction and enables transition to a stable maintenance period which is followed by a quiet and uneventful recovery.
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D005260:Female; D006140:Guaifenesin / Q000008:administration & dosage*; D006736:Horses / Q000601:surgery*; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D008297:Male; D011674:Pulse / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D013840:Thiamylal
chemical_list: D013840:Thiamylal; D006140:Guaifenesin