title: Vitamin-mineral supplement fails to improve IQ of mentally retarded young adults.
abstract: Twenty mentally retarded persons participated in a study to determine the effect of large doses of vitamin-mineral supplements on IQ, educability, electrophysiological responsiveness, and pyridoxine metabolism. Using a double-blind matched group experimental design, we administered supplements and placebos for 6 months. Pre- and postmeasurements showed no significant effects on any of the measured variables.
mesh_terms: D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D004487:Edema / Q000188:drug therapy; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D007360:Intelligence / Q000187:drug effects*; D008297:Male; D008903:Minerals / Q000627:therapeutic use*; D011736:Pyridoxine / Q000378:metabolism; D012640:Seizures / Q000188:drug therapy; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D008903:Minerals; D014815:Vitamins; D011736:Pyridoxine