The ultrastructural morphology of the subthalamic-nigral axon terminals intracellularly labeled with horseradish peroxidase.
The labeled axons of neurons intracellularly injected with horseradish peroxidase (HRP) in the rat subthalamic nucleus (STH) were studied with electron microscopy. The main axons and the efferent daughter branches were all myelinated. The morphology of the intrinsic axon terminals within STH was obscured by the dark HRP reaction products, but the labeled efferent STH terminals in the substantia nigra (SN) were revealed to contain small oval vesicles and formed asymmetrical synapses with dendrites of SN neurons.
D000818:Animals; D001369:Axons / Q000648:ultrastructure*; D003712:Dendrites / Q000648:ultrastructure; D004525:Efferent Pathways / Q000033:anatomy & histology; D005917:Globus Pallidus / Q000033:anatomy & histology; D006735:Horseradish Peroxidase; D008854:Microscopy, Electron; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure; D051381:Rats; D013378:Substantia Nigra / Q000033:anatomy & histology*; D013569:Synapses / Q000648:ultrastructure; D013787:Thalamic Nuclei / Q000033:anatomy & histology*
D006735:Horseradish Peroxidase