[Nitrogen metabolism in elderly persons on a low-calorie diet].
The clinical trials covered 9 men aged 58-73 years with daily energy losses of 2200-2350 kcal and given for 10 days the diet (1128 kcal/day) containing different food ingredients. A study was made of the main parameters of nitrogenous metabolism. During the time of being kept on a low-caloric diet, the test subjects lost 2.1 kg body mass. Excretion of total nitrogen dropped 34%, urea 57%. Excretion of creatinine appreciably rose (208% of the initial). The calculation of nitrogenous balance demonstrated protein deficiency to be equal to 209 g during experiments. The concentration of free amino acids in blood plasma decreased: that of replaceable by 29.5%, that of essential ones by 37.6%. It is assumed that the tension of body metabolism affected protein synthesis, whereas the protein quota in the diet did not appear sufficient for elderly subjects.
D000368:Aged; D000596:Amino Acids / Q000097:blood; D003404:Creatinine / Q000652:urine; D004038:Diet, Reducing; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D006801:Humans; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism*; D009765:Obesity / Q000178:diet therapy / Q000378:metabolism*; D014508:Urea / Q000652:urine
D000596:Amino Acids; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D014508:Urea; D003404:Creatinine; D009584:Nitrogen
Sostoianie azotistogo obmena u lits pozhilogo vozrasta, poluchavshikh redutsirovannuiu po kaloriĭnosti dietu.