Sodium-dependent calcium efflux from single Aplysia neurons.
45Ca2+ efflux from single Aplysia somata was measured. Replacement of external Na with Tris caused a reduction in the efflux following a transient increase. CCMP, a metabolic poison, caused a reversible increase in the efflux. The results suggest that Na+/Ca2+ exchange and mitochondrial uptake can act to regulate Ca2+ in Aplysia neurons.
D000818:Animals; D001048:Aplysia; D002118:Calcium / Q000378:metabolism*; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology; D002463:Cell Membrane Permeability / Q000187:drug effects; D066298:In Vitro Techniques; D009474:Neurons / Q000502:physiology*; D012964:Sodium / Q000502:physiology*
D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone; D012964:Sodium; D002118:Calcium