Polytetrafluoroethylene versus autogenous vein grafts for vascular reconstruction in contaminated wounds.
A high incidence of dissolution and disruption of infected autogenous vein grafts has been demonstrated. PTFE, on the other hand, has been shown to maintain its structural integrity in the presence of well-entrenched infection, with a relatively small incidence of anastomotic disruption related to host artery necrosis. In addition, PTFE performed as well as autogenous vein when antibiotics were administered. Therefore, PTFE graft material is advocated for controlled clinical trials in patients with contaminated vascular injuries.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001166:Arteriovenous Shunt, Surgical; D001807:Blood Vessel Prosthesis; D001808:Blood Vessels / Q000293:injuries*; D004285:Dogs; D005263:Femoral Artery / Q000601:surgery; D005268:Femoral Vein / Q000601:surgery; D007601:Jugular Veins / Q000637:transplantation; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications / Q000517:prevention & control; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000382:microbiology; D014182:Transplantation, Autologous; D014680:Veins / Q000637:transplantation*; D014946:Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D011138:Polytetrafluoroethylene