[Hypokalemic paralysis after prolonged absorption of a non-alcoholic pastis in a diabetic].
A typical case of glycyrrhizin-induced hypokalemic paralysis in a diabetic patient is presented. Hypokalemia was responsible for a generalized muscle weakness with a rise in serum muscular enzymes and cardiovascular disorders, which improved under potassium supplementation and spironolactone therapy. The pseudoaldosteronism syndrome with low plasma renin activity and aldosteron suggested aldosteron -like liquorice intoxication. Patient's interrogation revealed regular consumption of a common aperitive drink: a non-alcoholic pastis containing small amounts of glycyrrhizin. The discrepancy between the severity of clinical manifestations and the ingested amounts of glycyrrhizin is explained by the diabetic state.
D001628:Beverages / Q000009:adverse effects*; D048909:Diabetes Complications; D004359:Drug Therapy, Combination; D006035:Glycyrrhiza; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010243:Paralysis / Q000209:etiology* / Q000473:pathology; D010525:Peripheral Nerves / Q000473:pathology; D010936:Plant Extracts / Q000009:adverse effects*; D010946:Plants, Medicinal
D010936:Plant Extracts
Paralysie hypokaliémique après absorption prolongée d'un pastis sans alcool chez un diabétique.