title: Ontogeny of brain neurotensin in the rat: a radioimmunoassay study.
abstract: Concentrations of neurotensin-like immunoreactivity in several discrete brain areas were measured by radioimmunoassay in rats of different ages (2, 5, 10, 20, 30, and 60 days). Neurotensin-like immunoreactivity increased steadily from 2 to 30 days of age in the hypothalamus and then plateaued, while the preoptic area and amygdala concentrations peaked at 30 days of age. Brainstem neurotensin-like immunoreactivity concentrations increased from 2 to 10 days of age and decreased from 20 to 60 days of age. Several other regions showed no significant age-associated changes in neurotensin-like immunoreactivity.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000254:growth & development*; D005260:Female; D008297:Male; D009496:Neurotensin / Q000032:analysis*; D009842:Oligopeptides / Q000032:analysis; D010455:Peptides; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution; D029867:Xenopus Proteins
chemical_list: D009842:Oligopeptides; D010455:Peptides; D029867:Xenopus Proteins; D009496:Neurotensin; C016832:xenopsin