title: [Role of lung biopsy in a heart surgery center (a new method for the quantitative assessment of pulmonary hypertension by biopsy of the lung of patients with congenital heart defects)].
abstract: Forty-three lung biopsies taken from 42 patients with various congenital heart malformations with high pulmonary hypertension (aged from 8 months to 34 years) were studied by morphological and morphometric methods. Changes in the pulmonary vessels were evaluated according to Heat-Edwards' classification and morphometric classification of Rabinovitch , et al. The morphometric data give some additional information on the growth and development of peripheral vessels, the degree of hypertrophy of tunica media muscularis, a decrease in the size of arteries. The demonstration of considerable reduction in the number of peripheral arteries by morphometry constitutes a serious prognostic sign of further progression of sclerotic changes in the pulmonary vessels even in the early correction of the heart malformation.
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002300:Cardiac Care Facilities; D002648:Child; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000145:classification / Q000473:pathology* / Q000601:surgery; D006782:Hospitals, Special; D006801:Humans; D006976:Hypertension, Pulmonary / Q000145:classification / Q000473:pathology* / Q000601:surgery; D007223:Infant; D007432:Intraoperative Period; D008168:Lung / Q000473:pathology*; D008297:Male; D009031:Moscow
vernacular_title: Rol' biopsii legkogo v kardiokhirurgicheskom tsentre (novyĭ metod kolichestvennoĭ otsenki legochnoĭ gipertenzii v biopsii legkogo u bol'nykh vrozhdennymi porokami serdtsa).