title: Intraocular pressure after intracapsular cataract extraction.
abstract: We studied the incidence of postoperative intraocular pressure elevations in 42 patients following intracapsular cataract extraction with alpha-chymotrypsin (1:5,000) and noted 17% to develop pressures greater than 30 mm Hg and 38% greater than 24 mm Hg within a 48-hour time interval. Additionally, we studied the effect of a single immediate postoperative instillation of timolol maleate 0.5%; this was associated with a slight reduction of intraocular pressure at the three- and six-hour time intervals, but did not eliminate the pressure spikes.
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D002387:Cataract Extraction / Q000379:methods*; D002918:Chymotrypsin / Q000494:pharmacology* / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D013256:Steroids / Q000494:pharmacology / Q000627:therapeutic use; D013999:Timolol / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013256:Steroids; D013999:Timolol; D002918:Chymotrypsin