title: Selective breeding for high and low antibody responses to inactivated Newcastle disease virus in Japanese quails.
abstract: Two lines of Japanese quail were divergently selected for high and low antibody responses after being twice injected at 4 and 6 weeks of age with inactivated Newcastle disease virus antigen. After seven generations of selection, the serum antibody level in the high line was 24% greater than the level in the unselected control lines, whereas the low line antibody level was approximately 37% less than that in the control line. The estimated heritability (H2S + D) was approximately .12 +/- .50. The realized h2, calculated from coefficient of regression formula on seven generations (G3 to G9 ), was .07.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis / Q000235:genetics*; D001947:Breeding; D003370:Coturnix / Q000235:genetics* / Q000276:immunology / Q000502:physiology; D005260:Female; D005298:Fertility; D008297:Male; D009522:Newcastle disease virus / Q000276:immunology*; D010058:Oviposition; D011784:Quail / Q000235:genetics*; D012641:Selection, Genetic
chemical_list: D000914:Antibodies, Viral