Changes in monogalactosyl diacylglycerols, alkylgalactolipids and cerebroside fatty acid esters in maturing rat brain measured by high-performance liquid chromatography.
A newly developed high-performance liquid chromatography method was used to measure four nonpolar glycolipids in developing rat brain. The accumulation patterns of nonhydroxy- and hydroxycerebroside fatty acid esters were similar to those of myelin cerebrosides. In contrast, both monogalactosyl diacylglycerol and alkylgalactolipids reached maximal levels at the early stages of myelination.
D000375:Aging; D000818:Animals; D001921:Brain / Q000254:growth & development*; D001923:Brain Chemistry; D002554:Cerebrosides / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004075:Diglycerides / Q000032:analysis*; D038983:Galactolipids; D005989:Glycerides / Q000032:analysis*; D006017:Glycolipids / Q000032:analysis*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D002554:Cerebrosides; D004075:Diglycerides; D038983:Galactolipids; D005989:Glycerides; D006017:Glycolipids; C009909:monogalactosyldiacylglycerol