The development of the vibrissal cortical column: a 2-deoxyglucose study in the rat.
A column of SI cortex responding to stimulation of a single vibrissa can be visualized with [14C]2-deoxyglucose (2-DG) autoradiography. The development of C3 vibrissal column was investigated in rat pups aged 2, 4, 6, 8, 12 and 21 days. A patch of label corresponding to higher glucose utilization appeared at postnatal day (p.d.) 4 to 6 in the cortical plate. Between p.d. 6 and 12 it developed into a spindle-shaped column. The infragranular layers showed metabolic activation later than the upper laminae. The suitability of the 2-DG technique for studies of infant mammalian brain is discussed.
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development; D001345:Autoradiography; D003847:Deoxyglucose; D005145:Face; D006197:Hair; D051381:Rats; D011919:Rats, Inbred Strains; D012679:Sense Organs / Q000294:innervation* / Q000502:physiology; D013003:Somatosensory Cortex / Q000254:growth & development* / Q000378:metabolism
D003847:Deoxyglucose