Fulminant hepatic failure and fatal encephalopathy associated with Epstein-Barr virus infection.
A case of fulminant hepatic failure, associated with infectious mononucleosis, in a previously healthy 14-year-old girl is reported. Despite intensive therapy, which included the use of acyclovir, charcoal haemoperfusion, and measures to control her raised intracranial pressure (guided by serial EEG and auditory brainstem-evoked response recordings), the outcome was fatal.
D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D001927:Brain Diseases / Q000209:etiology* / Q000628:therapy; D002606:Charcoal; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000188:drug therapy; D007674:Kidney Diseases / Q000209:etiology* / Q000628:therapy
D002606:Charcoal; D000212:Acyclovir