Iohexol and metrizoate in urography in children. Comparison between a non-ionic and an ionic contrast medium.
Urography was performed with the non-ionic contrast medium iohexol in 21 children and with the ionic contrast medium metrizoate in 18 children. The quality of the urograms was good with both contrast media and there was no statistically significant difference between them in this respect. However, the contrast medium attenuation in the collecting system was higher with iohexol than with metrizoate. No renal damage was observed. Only minor adverse reactions were seen with both contrast media and more rarely in the iohexol group, but this difference was not statistically significant.
D002648:Child; D002675:Child, Preschool; D003287:Contrast Media / Q000009:adverse effects; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D007463:Iodobenzoates; D007472:Iohexol; D008297:Male; D008794:Metrizoic Acid / Q000009:adverse effects; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000009:adverse effects; D014567:Urography / Q000379:methods*
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008794:Metrizoic Acid