Effect of 30% sodium sulfacetamide on corneal sensitivity.
This study compares the effect of 10 and 30% sodium sulfacetamide on corneal sensitivity. The corneal sensitivity was measured on 11 subjects with a Cochet -Bonnet aesthesiometer without any drug, 10 and 30% sodium sulfacetamide . The results obtained for the mean corneal sensitivities (mean +/- standard error) for the control, 10 and 30% sodium sulfacetamide were 1.07 +/- 0.025, 1.09 +/- 0.023, and 1.36 +/- 0.10 gm/mm2, respectively. We found that there was no statistical difference between the control value and 10% sodium sulfacetamide , but the 30% produced a significant decrease in corneal sensitivity when compared to the control and 10% concentration.
D003315:Cornea / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D012677:Sensation / Q000187:drug effects*; D012684:Sensory Thresholds; D013409:Sulfacetamide / Q000494:pharmacology*
D013409:Sulfacetamide