Postnatal development of renal tubular amino acid reabsorption in canine pups.
The renal clearance of amino acids in canine pups 5 days and 3, 8, and 12 weeks of age was studied. The 5-day-old pups had incomplete reabsorption of most amino acids. At 3 weeks, fractional reabsorption of 16 of 21 amino acids was complete; between 3 and 8 weeks, an adult pattern of reabsorption was present. Seemingly, a rapid development of amino acid transport precedes anatomic development or functional maturation of other transport systems.
D000042:Absorption; D000367:Age Factors; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D004285:Dogs / Q000378:metabolism*; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism*; D008297:Male
D000596:Amino Acids