Disintegration of orthogonal arrays in perivascular astrocytic processes as an early event in acute global ischemia.
A quantitative freeze-fracture study of perivascular astrocytic processes in rat cerebral cortex disclosed rapid disintegration of orthogonal arrays of the intramembrane particles in acute global ischemia. The process apparently preceded the development of astrocytic swelling.
D000208:Acute Disease; D000818:Animals; D001253:Astrocytes / Q000648:ultrastructure*; D002545:Brain Ischemia / Q000473:pathology*; D002462:Cell Membrane / Q000648:ultrastructure; D002540:Cerebral Cortex / Q000648:ultrastructure*; D005614:Freeze Fracturing; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains