Synaptonemal complex studies in a mosaic 46,XY/47,XXY male.
We describe the results of synaptonemal complex (SCs) studies by light (LM) and electron microscopy (EM) in a sterile 46,XY/47,XXY male mosaic. Meiotic studies showed an arrest at the first spermatocyte level. Pachytene figures showed three types of cells: (1) cells with normal SCs, normal sex vesicle, and a 23,XY constitution; (2) cells with no sex vesicle, normal pairing of SCs, and a 24, (?) constitution; and (3) cells with a normal sex vesicle and fragmented SCs.
D000328:Adult; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics / Q000473:pathology*; D008297:Male; D008540:Meiosis; D009030:Mosaicism; D013090:Spermatocytes / Q000473:pathology