[Review of intra-arterial infusion-radiation therapy for lingual cancer].
Since 1974, we have performed intra-arterial infusion combined with radiation therapy in 137 cases of malignant tumor of the head and neck region. Of these 31 cases of lingual cancer are reviewed in the present paper. The cases were divided, according to the kind of infusional agent administered, into the following groups: BUdR X 5-FU (BAR), 13 cases and BUdR, 18 cases. Instances of death occurring in patients to which anti-cancer agents were applied were as follow: BAR, 8 cases (2 local recurrence, 1 lymph node metastasis, 3 unknown and 2 other causes) BUdR, 8 cases (2 local recurrence, 3 lymph node metastasis, 2 pulmonary metastasis, 1 unknown). Cases of death classified by stages included: (I) 2/6, (II) 4/10, (III) 8/13 and (IV 2/2. The shortest period of observation was 2 years and the longest 10. One of the 15 surviving cases has undergone hemiglossectomy due to recurrence, but the remaining 14 have not received any surgical treatment.
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001973:Bromodeoxyuridine / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*
D001973:Bromodeoxyuridine; D005472:Fluorouracil