title: Butyl hydroxy toluene antagonizes the gastric toxicity but not the pharmacological activity of acetylsalicylic acid in rats.
abstract: Butyl hydroxy toluene reduced gastric erosion due to acetylsalicylic acid in the rat, but not the antiinflammatory, anti-pyretic and analgesic activity. By itself, BHT exhibited activity only in the test on analgesia.
mesh_terms: D000698:Analgesia; D000818:Animals; D001241:Aspirin / Q000037:antagonists & inhibitors* / Q000627:therapeutic use / Q000633:toxicity; D002084:Butylated Hydroxytoluene / Q000494:pharmacology*; D002351:Carrageenan; D004487:Edema / Q000188:drug therapy; D005334:Fever / Q000188:drug therapy; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000187:drug effects*
chemical_list: D002084:Butylated Hydroxytoluene; D002351:Carrageenan; D001241:Aspirin