title: The prefrontal cortex of a prosimian (Galago senegalensis) is reached by efferent neurons originating in the nucleus basalis of Meynert.
abstract: Efferent projections from the basal forebrain to the prefrontal cortex of the lesser bush baby (Galago senegalensis) were traced with the retrograde horseradish peroxidase technique. Different areas of the prefrontal cortex of six bush babies were injected with small amounts of horseradish peroxidase. The entire basal forebrain was then screened for labeled neurons. Following all six injections, many retrogradely labeled neurons could be detected in the nucleus basalis of Meynert. These results indicate a strong innervation of the bush baby's prefrontal cortex by the nucleus basalis of Meynert. The observed projections seem comparable in strength and topography to those found in another primate species, the rhesus monkey. Anatomical and functional implications of these projections in the bush baby are discussed and related to findings in other primates and species of other orders.
mesh_terms: D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology*; D005625:Frontal Lobe / Q000033:anatomy & histology*; D005701:Galago / Q000033:anatomy & histology*; D008253:Macaca mulatta / Q000033:anatomy & histology; D009434:Neural Pathways / Q000033:anatomy & histology; D012453:Saimiri / Q000033:anatomy & histology; D013045:Species Specificity; D013377:Substantia Innominata / Q000033:anatomy & histology*