title: Computer simulation of plasma exchange therapy in autoimmune disease.
abstract: Computer simulation of plasma exchange in autoimmune disease shows that a single treatment may reduce the amount of antibody bound to antigen by as much as 60-80%. The reduction is greatest when autoantibody is of low affinity and there is an excess of antibody compared to antigen.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000628:therapy; D001327:Autoimmune Diseases / Q000628:therapy*; D003201:Computers; D006801:Humans; D008954:Models, Biological; D010951:Plasma Exchange