title: Serum concentrations of phenytoin after oral administration in rats.
abstract: Phenytoin (115 mg/kg) was given orally to rats in order to determine serum concentration levels of the drug. It was found that the peak concentration in serum was 8 micrograms/ml 1 h postadministration , with little variation being noted for up to 8 h. The relevance of these findings in terms of behavioral studies is discussed.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D007408:Intestinal Absorption; D008297:Male; D010672:Phenytoin / Q000008:administration & dosage / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010672:Phenytoin