title: [Pathology and physiology of microbes. IV. Economic and metabolic coefficients in assessing the functional states of Salmonella typhi].
abstract: The study of economic and metabolic coefficients under different conditions of batch and continuous cultivation with the use of S. typhi, a facultative anaerobe, as a model has demonstrated that the functional state of the microbial population is determined by the phase of the development of the culture, the composition of the culture medium, the conditions of aeration and stirring, the concentration of the energy-providing substrate and the dilution rate in continuous cultivation. The economic coefficient with respect to the energy-providing substrate has been found to be the main characteristic of the functional state of the population: the high values of this characteristic correspond to the physiological state of the population. The decrease of the economic coefficient below a certain critical value is indicative of the pathological state of the population.
mesh_terms: D000332:Aerobiosis; D002364:Caseins / Q000378:metabolism; D003470:Culture Media / Q000378:metabolism; D004526:Efficiency / Q000502:physiology; D004734:Energy Metabolism; D005947:Glucose / Q000378:metabolism; D046911:Macromolecular Substances; D012485:Salmonella typhi / Q000502:physiology*
chemical_list: D002364:Caseins; D003470:Culture Media; D046911:Macromolecular Substances; D005947:Glucose
vernacular_title: Patologiia i fiziologiia mikrobov. Soobshchenie IV. Ekonomicheskiĭ i metabolicheskiĭ koéffitsienty v otsenke funktsional'nykh sostoianiĭ Salmonella typhi.