title: The dynamics of the coronary venous system in the dog.
abstract: The coronary vascular system is characterised by a small blood-volume, high resistance arterial system, in which flow is primarily diastolic, a capillary-venule exchange system and a large blood volume, low resistance venous system with predominantly systolic flow. In order to understand the venous component we measured intramyocardial pressure (IMP), peripheral (PVP) and central (CVP) coronary venous pressure, as well as phasic coronary sinus outflow. Based on the experimental data, a model is proposed to describe the hemodynamics of the coronary venous system. This model consists of an intramyocardial vascular storage region into which the arterial blood flows during diastole. During systole, the pressure in the storage vessels increases, pushing the peripheral and epicardial venous system. Blocking the inflow tends to empty the 'storage' and the peripheral regions, reducing venous pressures. Occlusion of the outflow increases the blood volume in these regions, elevating venous pressures. The observations of peak (IMP-PVP) vs peak venous flow during vagal, right abd left stellate stimulation conform satisfactorily with the model.
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002496:Central Venous Pressure; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000502:physiology*; D004285:Dogs; D006439:Hemodynamics; D008954:Models, Biological; D012212:Rheology; D014690:Venous Pressure