Kaposi's sarcoma on a lymphedematous immunocompromised limb.
Kaposi's sarcoma appeared on a chronically lymphedematous leg of a 75-year-old man. Immunologic investigations revealed a lack of cellular immune response confined to the involved lower limb. Regional disorders of immune surveillance are thought to play an important role in the early stages of Kaposi's sarcoma.
D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007108:Immune Tolerance; D007111:Immunity, Cellular; D007866:Leg; D008209:Lymphedema / Q000150:complications* / Q000473:pathology; D008297:Male; D012514:Sarcoma, Kaposi / Q000150:complications / Q000276:immunology* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications / Q000276:immunology* / Q000473:pathology