[Radiosensitivity of thymocytes and bone marrow cells of the lymphoid series based on data from a study of the kinetics of spontaneous chemiluminescence].
Two peaks of spontaneous chemiluminescence (SHL), registered at a time of mass cell death (minutes 5 and 55), were detected in a suspension of intact thymocytes during a complement-depending cytotoxic test (CDCT) with anti-theta-serum. The second peak disappeared in suspensions irradiated with doses of 4, 6, 8 and 10 Gy; as the dose increased the first peak appeared at earlier times after irradiation (1-2 min), and cells died more rapidly. As to intact bone-marrow cells of a lymphoid series, a stimulatory effect of thymosin on the theta-antigen expression was detected during CDCT with a reference to the increased quantum yield of SCL. After irradiation of the suspension (6 and 8 Gy) cells died more rapidly and SCL peak appeared earlier. When CDCT was conducted 15 min after irradiation of rats (6 Gy) incubation with thymosin influenced the appearance of the peak at earlier times after irradiation.
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects*; D008163:Luminescent Measurements; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011836:Radiation Tolerance; D051381:Rats; D013950:Thymus Gland / Q000528:radiation effects*
Radiochuvstvitel'nost' timotsitov i kostnomozgovykh kletok limfoidnogo riada po dannym isledovaniia kinetiki spontannoĭ khemiliuminestsentsii.