[Level of dehydrogenase activity in chipmunks under normal conditions and during chronic external gamma-irradiation].
Chipmunks were chronically exposed to gamma-radiation at an average dose rate of 46 pA/kg. Changes in activity of succinate dehydrogenase (EC 1.3.99.1), pyruvate dehydrogenase (EC 1.2, 4.1) and lactate dehydrogenase (EC 1.1.1.27) were detected in the homogenates of the cardiac muscle, liver and brain at different physiological periods (before, during and after hibernation). The changes observed were related to the impairment of coordination between the processes of tissue respiration and glycolysis.
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000528:radiation effects; D005720:Gamma Rays; D006019:Glycolysis / Q000528:radiation effects; D006321:Heart / Q000528:radiation effects; D006605:Hibernation / Q000528:radiation effects; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000528:radiation effects; D009206:Myocardium / Q000201:enzymology; D010088:Oxidoreductases / Q000378:metabolism* / Q000528:radiation effects; D010101:Oxygen Consumption / Q000528:radiation effects; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D012589:Sciuridae / Q000378:metabolism*; D013385:Succinate Dehydrogenase / Q000378:metabolism
D011768:Pyruvate Dehydrogenase Complex; D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase
Uroven' aktvnosti degidrogenaz v norme i pri khronicheskom deĭstvii vneshnego gamma-oblucheniia u burundukov.