A quantitative study of mast cells in Hodgkin's disease.
Mast cells were counted in 45 specimens from patients with Hodgkin's disease and in five lymph nodes showing follicular hyperplasia. A consistent finding was that of few mast cells in the lymphocyte depleted and lymphocyte predominant Rye subtypes of Hodgkin's disease and in the mixed cellularity variant; however, mast cells were much more prevalent in nodular sclerosing Hodgkin's disease and in the hyperplastic nodes. The mast cells were selectively stained by means of the astra blue technique.
D002452:Cell Count; D006689:Hodgkin Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia / Q000150:complications; D008198:Lymph Nodes / Q000473:pathology*; D008231:Lymphopenia / Q000150:complications; D008407:Mast Cells / Q000473:pathology*