title: Immune mechanisms in the pathogenesis of chronic active hepatitis.
abstract: The present paper is a review of investigations concerning the pathogenesis of chronic active hepatitis (CAH). After a brief reexamination of the classification and etiology of CAH, details are given regarding the immunologic aspects of postviral CAH and of CAH considered as autoimmune. The work is a critical analysis of the mechanisms of both cellular immunity and humoral immunity, as well as of possible genetic disorders of the immune response.
mesh_terms: D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis; D006521:Hepatitis, Chronic / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D014777:Virus Diseases / Q000150:complications*
chemical_list: D001323:Autoantibodies