title: Validation of an equation for calculation of glucose appearance during nonsteady state in sheep.
abstract: The purpose of this study was to validate the calculation of the rate of glucose appearance (RA) during nonsteady state for sheep. The RA given by the modified single-compartment model was compared with the actual rate derived from the sum of the infusion of exogenous glucose and endogenous production as determined from hepatic production of glucose. Using a pool fraction of 0.65, the error associated with calculation of RA was about 10%.
mesh_terms: D000818:Animals; D005260:Female; D005947:Glucose / Q000096:biosynthesis / Q000378:metabolism*; D007700:Kinetics; D008102:Liver Circulation; D008954:Models, Biological; D009765:Obesity / Q000378:metabolism; D012756:Sheep
chemical_list: D005947:Glucose