title: Anticholinergic premedication in infants: a comparison of atropine and glycopyrrolate on heart rate, demeanor, and facial flushing.
abstract: Heart rate, demeanor, and facial flushing following intramuscular injection of atropine or glycopyrrolate were compared in 80 paediatric patients under 1 year of age. No significant differences occurred between the two drugs in the doses used. Neither was there any difference in drug response between those children aged under 2 months and the other patients in the study.
mesh_terms: D017109:Akathisia, Drug-Induced; D001285:Atropine / Q000494:pharmacology*; D005145:Face; D005483:Flushing; D006024:Glycopyrrolate / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D010276:Parasympatholytics / Q000494:pharmacology*; D011292:Premedication; D011759:Pyrrolidines / Q000494:pharmacology*
chemical_list: D010276:Parasympatholytics; D011759:Pyrrolidines; D001285:Atropine; D006024:Glycopyrrolate