title: Computer analyses of acoustical parameters in hypopituitary children before and after growth hormone treatment.
abstract: The effect of growth hormone treatment on voice quality, glottal frequency and articulatory pause was studied by computer analyses in 13 growth hormone-deficient children and age-matched controls. Each of the acoustical parameters when evaluated prior to the administration of growth hormone showed a deviation from the control subjects. Following treatment, improvement was noted in each of the parameters studied. It is concluded that growth hormone-deficient children have acoustical parameters which vary from age-matched controls, and that growth hormone plays a definite role in maturation of the phonatory apparatus.
mesh_terms: D000293:Adolescent; D002648:Child; D002657:Child Development / Q000187:drug effects; D003201:Computers; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007018:Hypopituitarism / Q000188:drug therapy*; D008297:Male; D010699:Phonation / Q000187:drug effects*; D013018:Sound Spectrography / Q000295:instrumentation; D014831:Voice / Q000187:drug effects*; D014833:Voice Quality / Q000187:drug effects*
chemical_list: D013006:Growth Hormone