Anticholinergic premedication in infants: a comparison of atropine and glycopyrrolate on heart rate, demeanor, and facial flushing.
Heart rate, demeanor, and facial flushing following intramuscular injection of atropine or glycopyrrolate were compared in 80 paediatric patients under 1 year of age. No significant differences occurred between the two drugs in the doses used. Neither was there any difference in drug response between those children aged under 2 months and the other patients in the study.
D017109:Akathisia, Drug-Induced; D001285:Atropine / Q000494:pharmacology*; D005145:Face; D005483:Flushing; D006024:Glycopyrrolate / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D010276:Parasympatholytics / Q000494:pharmacology*; D011292:Premedication; D011759:Pyrrolidines / Q000494:pharmacology*
D010276:Parasympatholytics; D011759:Pyrrolidines; D001285:Atropine; D006024:Glycopyrrolate