Tumor detection with some 99mTc-labeled S-containing amino acids.
99mTc-labeled L-cysteine, DL-homocysteine, and S-carbamyl-L-cysteine were prepared and tested for effectiveness in gamma camera imaging and for bioradiodistribution in mice bearing Ehrlich solid tumors. Among these labeled compounds, 99mTc-DL-homocysteine seems most promising for the nuclear medical imaging of tumors.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000000981:diagnostic imaging; D003545:Cysteine / Q000031:analogs & derivatives* / Q000378:metabolism; D006710:Homocysteine / Q000378:metabolism; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013667:Technetium; D014018:Tissue Distribution
D006710:Homocysteine; C006894:S-carbamylcysteine; D013667:Technetium; D003545:Cysteine