Plasma valine and urinary C-peptide in breast-fed and artificially fed infants up to 6 months of age.
Plasma branched-chain amino acids and urinary C-peptide-creatinine excretion was determined at 3, 4 1/2 and 6 months of age in a group of 50 infants who were either breast-fed or artificially fed and selected at random. The average concentrations of valine in plasma and C-peptide in urine as well as the ratio between C-peptide and creatinine in urine were 2-3 times higher (p less than 0.01) in artificially fed as compared to breast-fed infants at all the ages studied. Plasma valine values correlated significantly with the urinary C-peptide/creatinine ratio (r = 0.76, p less than 0.01), which suggests that the enhanced insulin response induced by the artificial formula is related to its protein content.
D000597:Amino Acids, Branched-Chain / Q000097:blood; D001903:Bottle Feeding; D001942:Breast Feeding; D002096:C-Peptide / Q000652:urine*; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D014633:Valine / Q000097:blood*
D000597:Amino Acids, Branched-Chain; D002096:C-Peptide; D003404:Creatinine; D014633:Valine