title: [Features of the manifestations of bronchopulmonary pathology and hepatitis B in children with hypogammaglobulinemia].
abstract: Two cases of hypogammaglobulinemia (Bruton's syndrome) in brothers are described. Their sisters had no this disease. Pronounced changes in the lymph nodes, spleen and thymus typical for this condition were combined in both cases with lung and kidney malformations as well as with chronic pneumonia and inanition. The both boys have viral respiratory infections that followed by marked antibody formation and clear-cut structural alterations characteristic of different stages of these diseases. Besides this the older brother was found to have chronic viral hepatitis B with an unusual giant-cell reaction.
mesh_terms: D000015:Abnormalities, Multiple / Q000150:complications*; D000361:Agammaglobulinemia / Q000235:genetics*; D002675:Child, Preschool; D006509:Hepatitis B / Q000150:complications*; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D008099:Liver / Q000002:abnormalities / Q000473:pathology; D008168:Lung / Q000002:abnormalities; D008297:Male; D012141:Respiratory Tract Infections / Q000150:complications; D013950:Thymus Gland / Q000473:pathology
vernacular_title: Osobennosti proiavleniĭ bronkholegochnoĭ patologii i gepatita B u deteĭ s gipogammaglobulinemieĭ.