title: The response range of the blue-cone pathways: a source of vulnerability to disease.
abstract: Retinal disease preferentially affects the sensitivity of the "blue"-cone pathways. This vulnerability to disease may be due, in part, to a more limited response range. A psychophysical technique, the probe-flash paradigm, was used to test this hypothesis. The data suggest that the S-cone pathways have a more limited response range than the L-cone pathways. Explanations for blue-cone vulnerability are discessed in the context of this finding.
mesh_terms: D004056:Differential Threshold; D006801:Humans; D010786:Photoreceptor Cells / Q000502:physiology*; D012164:Retinal Diseases / Q000503:physiopathology*; D014787:Vision Tests