title: Determination of 4-hydroxyanisole in serum using liquid chromatography with electrochemical detection.
abstract: 4-Hydroxyanisole (p-methoxyphenol) has been used in the treatment of malignant melanomas. A simple, sensitive, and specific, method for its determination by liquid chromatography with electrochemical detection (LCEC) is described. Vanillin (4-hydroxy-3-methoxybenzaldehyde) was used as an internal standard.
mesh_terms: D000840:Anisoles / Q000097:blood*; D001547:Benzaldehydes; D002853:Chromatography, Liquid / Q000379:methods*; D004563:Electrochemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration
chemical_list: D000840:Anisoles; D001547:Benzaldehydes; C009760:mequinol; C100058:vanillin