[Comparative study of intravenous midazolam and diazepam used as sedative agents during gastroscopy].
Midazolam was compared with diazepam for the intravenous sedation of gastroscopy patients. 0.1 mg X kg-1 midazolam were given to patients less than 65 years old, and 0.085 mg X kg-1 after that age; diazepam doses were 0,2 mg X kg-1 and 0.15 mg X kg-1 respectively. The effect and duration of action of both drugs were similar. The main differences between them were as follows: the intravenous injection of midazolam was not painful, and virtually no venous complications were seen; amnesia and patient contentedness were more frequent with midazolam; gastric secretion was reduced with midazolam. Neither drug had clinically significant cardiovascular effects.
D001569:Benzodiazepines / Q000008:administration & dosage*; D003975:Diazepam / Q000008:administration & dosage*; D005773:Gastroscopy; D006801:Humans; D007275:Injections, Intravenous; D008874:Midazolam; D008875:Middle Aged
D001569:Benzodiazepines; D003975:Diazepam; D008874:Midazolam
Etude comparative du midazolam et du diazépam intraveineux comme agents de sédation en endoscopie digestive.