GABA uptake by purified rat schwann cells in culture.
Purified rat Schwann cells maintained in culture for up to 6 months retained their ability to take up the neurotransmitter gamma-aminobutyric acid (GABA) by a high-affinity mechanism. Although cultured fibroblasts also accumulated GABA, they did so by a low affinity mechanism. These results indicate that Schwann cells continue to express a high affinity GABA transport system in the absence of signals from neurons.
D000818:Animals; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D051381:Rats; D011919:Rats, Inbred Strains; D012583:Schwann Cells / Q000378:metabolism*; D012964:Sodium / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D012964:Sodium