Basal cell nevus syndrome. Unresponsiveness of early cutaneous lesions to topical 5-fluorouracil or dinitrochlorobenzene.
A single patient with basal cell nevus syndrome is presented. Prolonged application of 5% 5-fluorouracil and dinitrochlorobenzene was unsuccessful in inducing regression or clearing of his cutaneous lesions. Our results suggest that these therapies, at least for the nevoid-appearing lesions, may not be effective in the management of some patients with basal cell nevus syndrome.
D000287:Administration, Topical; D001478:Basal Cell Nevus Syndrome / Q000188:drug therapy* / Q000601:surgery; D002280:Basal Cell Carcinoma / Q000188:drug therapy*; D002648:Child; D004137:Dinitrochlorobenzene / Q000627:therapeutic use*; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009578:Nitrobenzenes / Q000627:therapeutic use*
D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes; D005472:Fluorouracil