title: Carcinoma of the colon and rectum in patients under 30 years of age.
abstract: A 15-year study of large-bowel carcinoma at Groote Schuur Hospital revealed 47 patients who presented at the age of 29 years or younger. Only 1% of the White patients with large-bowel carcinoma were in this age group (similar to other Western series), whereas a much higher incidence was seen in Coloured patients (9%). We found a large number of young Coloured patients with high-grade tumours and lymph node invasion. In spite of surgery, chemotherapy and radiotherapy the prognosis for this group in particular remains extremely poor.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D044383:Black People; D002648:Child; D003110:Colonic Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D012737:Sex Factors; D013019:South Africa; D044465:White People