Non-mutagenicity of some wood-related compounds in the bacterial/microsome plate incorporation and microsuspension assays.
Seven commercially available wood-related compounds have been tested for mutagenicity by the use of the Ames and fluctuation test-systems. All compounds were found to be non-mutagenic. Among these compounds, 2,6-dimethoxy-p-benzoquinone showed a very weak and questionable mutagenic activity against Salmonella typhimurium TA 100. In this connection, probable causes of nasal adenocarcinoma of woodworkers are briefly discussed.
D000818:Animals; D016227:Benzoquinones; D002273:Carcinogens; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis*; D009669:Nose Neoplasms / Q000139:chemically induced; D009784:Occupational Diseases / Q000139:chemically induced; D010416:Pentachlorophenol / Q000633:toxicity; D011809:Quinones / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D012603:Scopoletin / Q000633:toxicity; D013535:Suspensions; D014934:Wood
D016227:Benzoquinones; D002273:Carcinogens; D009153:Mutagens; D011809:Quinones; D013535:Suspensions; C030511:2,6-dimethoxy-1,4-benzoquinone; D010416:Pentachlorophenol; D012603:Scopoletin