Midazolam as induction agent prior to inhalational anaesthesia: a comparison with thiopentone.
Midazolam, a new water-soluble benzodiazepine, was compared with thiopentone as an induction agent prior to inhalational anaesthesia. Induction time, cardiovascular response and venous sequelae were studied in 100 healthy in-patients randomly divided into two groups. Midazolam proved to be a good alternative to thiopentone, the longer induction time being compensated by a lower incidence and duration of apnoea.
D000293:Adolescent; D000328:Adult; D000769:Anesthesia, Inhalation; D001569:Benzodiazepines / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D011229:Preanesthetic Medication; D011897:Random Allocation; D013874:Thiopental / Q000494:pharmacology*
D001569:Benzodiazepines; D013874:Thiopental; D008874:Midazolam