[Biotesting of a burn toxin on mice with reticuloendothelial system block].
Experiments on mice with reticuloendothelial system blockade were made to assay the toxic properties of the preparations obtained from the skin of burn and normal rats. As regards the activity level the preparations can be classified with either highly toxic or little toxic. Analysis of the dose-response dependence indicates that toxicity of the extracts is accounted for by at least two different toxins.
D000818:Animals; D001681:Biological Assay / Q000379:methods; D002056:Burns / Q000276:immunology*; D002244:Carbon; D004396:Coloring Agents / Q000494:pharmacology; D004306:Dose-Response Relationship, Immunologic; D007928:Lethal Dose 50; D051379:Mice; D008970:Molecular Weight; D012157:Mononuclear Phagocyte System / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000276:immunology; D014020:Tissue Extracts / Q000633:toxicity; D014118:Toxins, Biological / Q000633:toxicity*
D004396:Coloring Agents; D014020:Tissue Extracts; D014118:Toxins, Biological; C028433:chinese ink; D002244:Carbon
Biotestirovanie ozhogovogo toksina na myshakh s blokadoĭ retikuloéndotelial'noĭ sistemy.