Erythrophagocytosis by segmented neutrophils in paroxysmal cold hemoglobinuria.
The authors report a case of paroxysmal cold hemoglobinuria (PCH) with pronounced erythrophagocytosis by segmented neutrophils. This type of erythrophagocytosis, though well-documented in vitro, is a rare phenomenon in vivo. A review of the literature shows an association between PCH and erythrophagocytosis by segmented neutrophils that the authors suggest may have diagnostic value.
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis; D002675:Child, Preschool; D003080:Cold Temperature / Q000009:adverse effects*; D003165:Complement System Proteins / Q000276:immunology; D004912:Erythrocytes; D006457:Hemoglobinuria, Paroxysmal / Q000097:blood / Q000175:diagnosis*; D006460:Hemolysin Proteins / Q000032:analysis; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000502:physiology; D010587:Phagocytosis
D006460:Hemolysin Proteins; D003165:Complement System Proteins