title: The effect of alpha-tocopherol and ascorbic acid on the serum lipid peroxide level in elderly people.
abstract: The aim of this work was to study the relationship between the state of saturation of the organism with vitamin E and vitamin C and the serum level of lipid peroxides in elderly people. The determinations were carried out in 100 subjects, mainly women, aged 60-100 years living in old people's homes, who were given daily vitamin E, 200 mg, or vitamin C, 400 mg, or both vitamins during 1 year. A correlation was found between the degree of saturation of the organism with vitamin E and the level of lipid peroxides. The daily intake of vitamin E for 4 months decreased the serum peroxide level by a mean value of 14%; a similar intake of vitamin C decreased it by 8%, and both vitamins decreased it by 20% compared with the initial level. After 1 year, these levels were decreased by 26% (vitamin E), 13% (vitamin C) and 25% (both vitamins).
mesh_terms: D000368:Aged; D001205:Ascorbic Acid / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D008054:Lipid Peroxides; D014810:Vitamin E; D001205:Ascorbic Acid