title: Angioid streaks associated with hereditary spherocytosis.
abstract: We examined members of a family in whom hereditary spherocytosis had appeared in three generations. Angioid streaks were confirmed in the second generation and presumed to exist in the first generation. A woman in the third generation with hereditary spherocytosis did not have angioid streaks but these are age-related and may develop later. The one individual in the second generation without hereditary spherocytosis did not have angioid streaks. Angioid streaks associated with hereditary spherocytosis in this family did not appear to be coincidental. Patients with hereditary spherocytosis should be examined for angioid streaks because of the implications for their vision.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002114:Calcinosis / Q000473:pathology; D002829:Choroid / Q000473:pathology*; D005128:Eye Diseases / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013103:Spherocytosis, Hereditary / Q000473:pathology*