Inhibitors of hydrogen peroxide-induced haemolysis of bovine erythrocytes.
The optimal conditions for the haemolysis of bovine erythrocytes by H2O2 have been established. The parameters were concentration of erythrocytes, H2O2 concentration, time, and influence of the solvent in which the substances tested were dissolved. Some inhibitors of this oxidative haemolysis have been employed to serve as model substances for further antihaemolytic investigations with natural products.
D000085:Acetates / Q000494:pharmacology; D000818:Animals; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D006461:Hemolysis / Q000187:drug effects*; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D066298:In Vitro Techniques; D010636:Phenols / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000085:Acetates; D010636:Phenols; D006861:Hydrogen Peroxide