Porcine Haemophilus pleuropneumonia: microbiologic and pathologic findings.
Haemophilus pleuropneumoniae was isolated from 11% of porcine lung specimens submitted to the University of Illinois Diagnostic Laboratory during 1979-1982. Acute necrotizing fibrinous bronchopneumonia was the most common diagnosis; 65% of lungs had severe involvement of the caudal lobes; 10% of lungs had unilateral involvement only. In 46% of lungs, a second pathogen was isolated. Isolates of H pleuropneumoniae tested by the Kirby-Bauer disk method were most sensitive to nitrofurazone (100%), polymyxin B (97%), chloramphenicol (95%), gentamicin (94%), sulfachloropyridazine (87%), ampicillin (83%), and penicillin (77%). Isolates were less sensitive to 9 other antimicrobials tested. Over 4 years in 1 herd, succeeding isolates of H pleuropneumoniae developed resistance to ampicillin, streptomycin, bacitracin, lincomycin, penicillin, and tetracycline.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001996:Bronchopneumonia / Q000382:microbiology / Q000662:veterinary*; D004352:Drug Resistance, Microbial; D006190:Haemophilus / Q000187:drug effects / Q000302:isolation & purification*; D008168:Lung / Q000382:microbiology / Q000473:pathology; D012189:Retrospective Studies; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*; D013997:Time Factors
D000900:Anti-Bacterial Agents