Juvenile polyposis of the colon with atypical adenomatous changes and carcinoma in situ. Report of a case and review of the literature.
Juvenile polyps are thought to have no malignant potential; however, we report a case of diffuse juvenile polyposis coli in a 19-year-old man where mucosal dysplastic changes ranging from mild dysplasia to carcinoma in situ are present. The pathogenetic development of these polyps and their malignant potential are discussed.
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D002278:Carcinoma in Situ / Q000473:pathology*; D003111:Colonic Polyps / Q000473:pathology*; D006801:Humans; D008297:Male; D011230:Precancerous Conditions / Q000473:pathology*