title: Genetics of mitochondrial glutamate-oxaloacetate transaminase (GOT-2) in Tigriopus californicus.
abstract: Glutamate-oxaloacetate transaminase (GOT; EC 2.6.1.1) occurs as two electrophoretically distinguishable isozymes in the copepod Tigriopus californicus. The slower-migrating form, referred to as GOT2 , is shown to be associated with the mitochondrial cell fraction. GOT2 phenotypes are inherited in typical Mendelian fashion, indicating that they are encoded by a nuclear gene. Allelic frequencies for electrophoretic variants of the two Got loci in 12 California populations of T. californicus show a sharp differentiation of local populations. Linkage studies demonstrated that Got-2 is linked to Got-1; a map of four loci in linkage group I is presented.
mesh_terms: D000483:Alleles; D000818:Animals; D001219:Aspartate Aminotransferases / Q000235:genetics*; D003445:Crustacea / Q000201:enzymology / Q000235:genetics*; D008040:Genetic Linkage; D014644:Genetic Variation; D007527:Isoenzymes / Q000235:genetics; D008928:Mitochondria / Q000201:enzymology; D010641:Phenotype
chemical_list: D007527:Isoenzymes; D001219:Aspartate Aminotransferases