Azapropazone-associated antibodies.
2 patients on the drug azapropazone developed positive antiglobulin tests. Their sera were each found to contain two distinct antibodies. One was an IgG antibody, probably a drug-dependent autoantibody of the alpha-methyldopa type, but could have been related to the disease. The other was certainly a drug-dependent antibody of the penicillin type.
D000368:Aged; D001032:Apazone / Q000009:adverse effects / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D003298:Coombs Test; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D007518:Isoantibodies / Q000276:immunology; D008875:Middle Aged; D014227:Triazines / Q000276:immunology*
D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007518:Isoantibodies; C033242:RH-antibodies; D014227:Triazines; D001032:Apazone