title: Clinical observations on ten cases of methanol poisoning with particular reference to ocular manifestations.
abstract: Clinical observations on 10 cases of methanol poisoning, with particular reference to ocular manifestations, are reported. Four patients stated that they had blurring of vision, one of these also had a temporary loss of the lower parts of the visual fields and another one visual hallucinations. Hyperaemia or oedema of the optic discs were found in 5 patients. Two of the patients died, another was severely ill and suffered from impaired vision for a long period of time afterwards. In none of the surviving patients detectable remaining damage to the retina could be revealed by recording the a- and the b-waves of the electroretinogram. Recording of the visual evoked responses showed that one patient had transient subnormal amplitudes in one eye. However, on follow-up registrations all of the patients had values within normal limits. The results of the investigation show a considerable individual variation in susceptibility to methanol poisoning.
mesh_terms: D000293:Adolescent; D000328:Adult; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D000432:Methanol / Q000506:poisoning*; D008875:Middle Aged; D009887:Ophthalmoscopy; D014786:Vision Disorders / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000432:Methanol