Oxygen supply of skeletal muscle in experimental endotoxic shock.
In our model of hypodynamic endotoxic shock systemic pulmonary and metabolic alterations such as -hypotension, tachycardia, low output syndrome -pulmonary hypertension -pulmonary failure with arterial hypoxemia and - lactacidosis developed earlier than disturbances in oxygen supply of skeletal muscle. This points to the different responses of the organ systems in endotoxic shock.
D000818:Animals; D001794:Blood Pressure; D002302:Cardiac Output; D006339:Heart Rate; D008833:Microcirculation; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D011652:Pulmonary Circulation; D011659:Pulmonary Gas Exchange; D012772:Shock, Septic / Q000378:metabolism* / Q000503:physiopathology; D013552:Swine