title: [Treatment of chronic obstructive respiratory disease with a new purified theophylline preparation in delayed-action form].
abstract: The treatment of chronic obstructive respiratory diseases with sustained release theophylline is steadily gaining in importance. Body plethysmography is applied for evaluating the extent of bronchospasmolysis during therapy of a new sustained release formula. A traditional prolonged-action theophylline-ethylenediamine preparation was administered to obtain comparative data. The sustained release formula containing pure theophylline meets the standards of a modern theophylline therapy. The graduation of the film tablet allows individualized dosage without losing the sustained release action by slowly increasing the theophylline-serum-level during a dosage interval of 12 hours.
mesh_terms: D000368:Aged; D000403:Airway Resistance / Q000187:drug effects; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010993:Plethysmography, Whole Body; D012129:Respiratory Function Tests; D013806:Theophylline / Q000008:administration & dosage* / Q000032:analysis / Q000097:blood
chemical_list: D003692:Delayed-Action Preparations; D013806:Theophylline
vernacular_title: Behandlung der chronisch obstruktiven Atemwegserkrankung mit einem neuen reinen Theophyllin-Präparat in retardierter Form.