[Effect of no-spa on the level of liver glucocorticoid receptors and on the biochemical indices of homeostasis in adrenalectomized rats].
It has been shown in experiments on adrenalectomized male rats that no-spa (0.2 ml of 2% solution per 100 g bw injected 3 times) increases significantly the level of type II and III glucocorticoid receptors in liver cytosol, the content of glucose and protein in the blood and liver. Animals receiving no-spa demonstrated a substantial increase in oxygen partial tension and saturation of venous blood hemoglobin with oxygen.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D003600:Cytosol / Q000187:drug effects; D006706:Homeostasis / Q000187:drug effects*; D008099:Liver / Q000187:drug effects*; D008297:Male; D010100:Oxygen / Q000097:blood; D010208:Papaverine / Q000031:analogs & derivatives* / Q000494:pharmacology; D010313:Partial Pressure; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000187:drug effects*; D011987:Receptors, Steroid / Q000187:drug effects*
D011965:Receptors, Glucocorticoid; D011987:Receptors, Steroid; C005317:drotaverin; D010208:Papaverine; D010100:Oxygen
Vliianie no-shpy na uroven' gliukokortikoidnykh retseptorov pecheni i biokhimicheskie pokazateli gomeostaza u adrenaléktomirovannykh krys.