Acute physiological responses during blood substitution with colloidal gelatin in conscious rats.
The effects of exchange-transfusion with a proprietary gelatin-based plasma volume expander, Haemaccel, have been investigated in conscious, chronically-catheterized rats. No adverse changes in basic cardiovascular or respiratory functions occurred during the procedure although an increase in intravascular fluid sodium but not potassium concentration was observed.
D000818:Animals; D003102:Colloids; D005260:Female; D005780:Gelatin; D006400:Hematocrit; D006439:Hemodynamics; D011097:Polygeline; D011108:Polymers; D011188:Potassium / Q000097:blood; D051381:Rats; D012119:Respiration; D012964:Sodium / Q000097:blood
D003102:Colloids; D011108:Polymers; D005780:Gelatin; D011097:Polygeline; D012964:Sodium; D011188:Potassium