[Biological action of radioactive carbon. Biological effects of large amounts of radioactive carbon (14C-glycine)].
In experiments on CBA X C57B16 mice a study was made of the acute effects of radiocarbon (14C-glycine) administered intraperitoneally in doses of 130, 60, 30 and 15 mBq/animal (the total cumulative doses absorbed within the body were, at an average, 29.5, 14.2, 7.1 and 3.6 Gy, respectively). In the first group, the animals developed grave radiation affections (50% death, average life-span of 17.6 days); in the second group, the affection was less serious, and in the third and fourth groups, the affection was light. A mean tissue absorbed dose in the died animals was 6-11 Gy.
D000818:Animals; D002250:Carbon Radioisotopes / Q000008:administration & dosage*; D004906:Erythrocyte Count; D005998:Glycine / Q000008:administration & dosage*; D006454:Hemoglobins / Q000032:analysis; D007274:Injections, Intraperitoneal; D007958:Leukocyte Count; D008297:Male; D051379:Mice; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000209:etiology*; D014018:Tissue Distribution
D002250:Carbon Radioisotopes; D006454:Hemoglobins; D005998:Glycine
Biologicheskoe deĭstvie radioaktivnogo ugleroda. Biologicheskie éffekty bolshikh kolichestv radioaktivnogo ugleroda (14C-glitsina).