Antibiotics for intraabdominal sepsis. Selection of an effective combination.
Optimum management of intraabdominal sepsis requires the judicious use of appropriate surgical procedures and simultaneous antibiotic administration. A number of appropriate antibiotics and antibiotic combinations are available for intraabdominal sepsis, but most data still favor combinations of an antiaerobic drug, most often an aminoglycoside, and an antianaerobic drug--and possibly a third agent effective against enterococci.
D000005:Abdomen; D000038:Abscess / Q000188:drug therapy / Q000601:surgery; D000617:Aminoglycosides / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000150:complications; D002981:Clindamycin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004322:Drainage; D004359:Drug Therapy, Combination; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D007239:Infections / Q000188:drug therapy* / Q000601:surgery; D010437:Peptic Ulcer / Q000150:complications; D010538:Peritonitis / Q000188:drug therapy; D011292:Premedication
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005839:Gentamicins; D002981:Clindamycin