Endoscopical determination of gastric mucosal blood flow by the crossed thermocouple method.
A crossed thermocouple method in combination with endoscopy was applied to determine the blood flow rate of the human gastric mucosa. Determination was carried out with 11 healthy control subjects at 8 sites of the stomach. The blood flow rates at all sites in the corpus were found to be higher than those at the antrum. In subjects less than 50 years old the blood flow rate in the corpus was higher than in older subjects. These results were in agreed well with those obtained by the hydrogen gas clearance method, which is widely adopted clinically. The crossed thermocouple method is easily applicable to all sites in the gastric mucosa and the time required for the assay is very short. This method dose not require the inhalation of hydrogen gas which is necessary for the hydrogen gas clearance method and which is possibly harmful to humans. Although the values obtained by the crossed thermocouple method are relative to the value at a certain fixed site, this method will holds great potential for the determination of gastric mucosal blood flow rate.
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D005753:Gastric Mucosa / Q000098:blood supply*; D020699:Gastroscopes; D006801:Humans; D006859:Hydrogen; D008297:Male; D008875:Middle Aged; D012212:Rheology / Q000379:methods*; D013696:Temperature
D006859:Hydrogen