Purification and some properties of ketone reductase forming an active metabolite of sodium 2-[4-(2-oxocyclopentylmethyl)-phenyl]propionate dihydrate (loxoprofen sodium), a new anti-inflammatory agent, in rabbit liver cytosol.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007658:Ketone Oxidoreductases / Q000032:analysis* / Q000302:isolation & purification; D008099:Liver / Q000201:enzymology*; D008297:Male; D010666:Phenylpropionates / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
D000893:Anti-Inflammatory Agents; D010666:Phenylpropionates; C040656:loxoprofen; D007658:Ketone Oxidoreductases