[The effect of visible light on the stability of isoprenaline, epinephrine and levarterenol solutions in various containers. 86. Problems in the use of plastic containers for liquid preparations. 21. The stability of drugs and preparations].
The stability of solutions of phenylalkylamines of the benzcatechine type was investigated in containers of different structure under influence of diffuse day light, direct sun light and artificial visible light. Thereby a combined influence of different the decomposition increasing factors could be observed. The decompositions were slowest in containers of PE-ND with pigment additionals and were increased from PE-HD, PE-ND, colourless glas up to brown glas .
D004349:Drug Packaging; D004355:Drug Stability; D004837:Epinephrine / Q000032:analysis*; D007545:Isoproterenol / Q000032:analysis*; D008027:Light / Q000009:adverse effects*; D009638:Norepinephrine / Q000032:analysis*; D010969:Plastics; D012996:Solutions; D013472:Sunlight / Q000009:adverse effects; D014466:Ultraviolet Rays / Q000009:adverse effects
D010969:Plastics; D012996:Solutions; D007545:Isoproterenol; D009638:Norepinephrine; D004837:Epinephrine
Einfluss des sichtbaren Lichtes auf die Haltbarkeit von Isoprenalin-, Epinephrin- und Levarterenollösungen in unterschiedlichen Behältnissen. 86. Mitteilung: Beiträge zur Problematik des Einsatzes von Kunststoffbehältern für flüssige Arzneizubereitungen; 21. Mitteilung: Stabilität von Arzneistoffén und Zubereitungen.