Absence of platelet activating factor (PAF) mediated platelet aggregation: a new platelet defect.
The failure of normal human platelets to aggregate in response to platelet activating factor (PAF) has not been previously observed. We report here the first case of a patient whose platelets did not aggregate to PAF on multiple occasions.
D000328:Adult; D001779:Blood Coagulation Factors / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D010972:Platelet Activating Factor; D010974:Platelet Aggregation / Q000187:drug effects*; D013917:Thrombin / Q000494:pharmacology
D001779:Blood Coagulation Factors; D010972:Platelet Activating Factor; D013917:Thrombin; D004837:Epinephrine