[Alagille's syndrome. Clinical and histo-pathologic study].
Alagille 's syndrome, described in 1970, associates a chronic intrahepatic cholestasis (hypoplasia of the interlobulary biliary ducts), vertebral and visceral malformations, retarded physical, mental and sexual development and neonatal jaundice. A series of cutaneous manifestations are reviewed in their clinical, histological and ultrastructural aspects. Its relation with the zinc deficiency syndrome is discussed.
D000015:Abnormalities, Multiple / Q000473:pathology*; D002675:Child, Preschool; D002780:Cholestasis, Intrahepatic / Q000150:complications; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008854:Microscopy, Electron; D012871:Skin Diseases / Q000150:complications / Q000473:pathology*; D013131:Spine / Q000002:abnormalities; D013577:Syndrome
Le syndrome D'alagille. Etude clinique et histo-pathologique.