Pneumonitis, pleural effusion and pericarditis following treatment with dantrolene.
A patient developed pulmonary infiltration, pleural effusions and pericarditis three months after starting dantrolene sodium. Peripheral blood eosinophilia and a raised ESR were present. Symptoms and signs resolved after the drug was discontinued. Dantrolene toxicity should be considered in the differential diagnosis of pneumonitis and pleuro-pericarditis.
D000328:Adult; D003620:Dantrolene / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009128:Muscle Spasticity / Q000188:drug therapy; D010493:Pericarditis / Q000139:chemically induced*; D010996:Pleural Effusion; D011014:Pneumonia / Q000139:chemically induced*; D013902:Radiography, Thoracic
D003620:Dantrolene