Phagocytic uptake of synthetic particles in blood leukocytes of fetal and newborn athymic nude mice.
Monocytes are the main phagocytic element in the blood of fetal mice; monocytes of athymic nude mouse fetuses (gestation days 17-20) ingest in vitro, in full blood, significantly more synthetic (HEMA) particles than the monocytes of their euthymic littermates. Blood leukocytes of athymic fetuses also bear much higher densities of Fc receptors for IgG2B. The differences in phagocytic uptake in blood leukocytes disappear and the differences in Fc(IgG2B) receptors decrease at postnatal days 2 and 4.
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D051379:Mice; D008819:Mice, Nude / Q000276:immunology*; D010587:Phagocytosis; D011247:Pregnancy; D011961:Receptors, Fc
D011961:Receptors, Fc