Area estimation in pharmacokinetic studies using a hand-held programmable calculator.
A short program for area analysis in pharmacokinetic studies using the Hewlett-Packard HP41C hand-held programmable calculator is described. Area under the concentration-time curve is calculated firstly within defined time limits and then with extrapolation to infinite time using the slope constant of the terminal phase. Input of concentration-time data is simple and there is no limit on the number of time-concentration co-ordinates which can be entered for area calculation.
D003201:Computers; D006801:Humans; D007700:Kinetics; D004364:Pharmaceutical Preparations / Q000097:blood*
D004364:Pharmaceutical Preparations