title: Fat absorption after longitudinal pancreaticojejunostomy.
abstract: This study was undertaken to determine whether fat absorption is improved following longitudinal pancreaticojejunostomy. Ten consecutive patients with chronic pancreatitis underwent measurement of fat absorption (fecal fat, 14C-labeled phenylacetic dipalmitate oil absorption test) before and after operation. Fecal fat increased in 8 of 10 patients following side-to-side pancreaticojejunostomy. However, the average postoperative fecal fat increase of 4.3 gm was of no clinical significance. The observed mild postoperative decline in fat absorption was confirmed by the 14C-labeled phenylacetic dipalmitate test. An improvement in postoperative fat absorption following side-to-side pancreaticojejunostomy Roux-en-Y should not be expected. The primary indication for this procedure for patients with chronic pancreatitis continues to be intractable pain.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004041:Dietary Fats / Q000378:metabolism*; D005243:Feces / Q000032:analysis; D005260:Female; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D008055:Lipids / Q000032:analysis; D008297:Male; D010148:Intractable Pain / Q000628:therapy; D010179:Pancreas / Q000601:surgery*; D010183:Pancreatic Ducts / Q000601:surgery; D010195:Pancreatitis / Q000378:metabolism / Q000601:surgery*; D010648:Phenylacetates; D013997:Time Factors
chemical_list: D004041:Dietary Fats; D008055:Lipids; D010648:Phenylacetates; C035869:phenylacetic dipalmitate