Proteolipid and collagen calcification, in vitro.
Initiation of in vitro calcification with insoluble type I collagen appears to be a function of tightly-bound proteolipid. The collagen preparation calcified during incubation in a metastable calcium phosphate solution before but not after lipid extraction. Calcifiability of the extracted lipid, similarly incubated, was restricted to the proteolipid fraction.
D000596:Amino Acids / Q000032:analysis; D002113:Calcification, Physiologic; D002130:Calcium Phosphates / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D066298:In Vitro Techniques; D008954:Models, Biological; D011485:Protein Binding; D011510:Proteolipids / Q000378:metabolism*
D000596:Amino Acids; D002130:Calcium Phosphates; D011510:Proteolipids; D003094:Collagen