Stimulus deprivation amblyopia. Simultaneous recording of local macular electroretinogram and visual evoked response.
Local macular electroretinogram (ERG) and visual evoked response (VER) were recorded simultaneously in ten adult patients with stimulus deprivation amblyopia. The fundus was monitored by an infrared television fundus camera. The location of the stimulus spot and eccentric fixating point were also monitored during recording. Responses in amblyopic eyes were compared with those in the normal fellow eyes in terms of the size of the stimulus spot, location of the eccentric fixating point in response to the stimulus spot, and visual acuity. The amplitude of VER in the amblyopic eye showed enhancement when the stimulus spot centering around the fovea involved the eccentric fixating point. The amplitude and peak time of the ERG in the amblyopic eye was essentially normal regardless of the degree of eccentricity of the fixating point and visual acuity.
D000293:Adolescent; D000328:Adult; D000550:Amblyopia / Q000209:etiology / Q000503:physiopathology*; D004596:Electroretinography / Q000379:methods*; D005074:Evoked Potentials, Visual; D005260:Female; D005403:Fixation, Ocular; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D012683:Sensory Deprivation; D014792:Visual Acuity