title: The diurnal fluctuations in unincorporated radio-thymidine pool and its relation to the circadian rhythm of thymidine incorporation in mouse pinna skin.
abstract: The circadian variation in the labelling indices of epidermal basal and sebaceous gland cells in murine pinna is a well documented phenomenon. This, however, observes only the incorporated label and takes no account of any rhythmic changes in the precursor pool. It is reported here that, using a liquid scintillation counting method, there is a diurnal change in the level of unincorporated radio-labelled thymidine, which is apparently not related to the rhythm of thymidine incorporation. The implications of this phenomenon and its relationship to DNA synthesis are discussed.
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D004431:Ear, External; D008297:Male; D051379:Mice; D012867:Skin / Q000378:metabolism*; D013936:Thymidine / Q000378:metabolism*; D014316:Tritium
chemical_list: D014316:Tritium; D013936:Thymidine