title: Depressive psychopathology in male sleep apneics.
abstract: Depression has been reported to be frequent in sleep apnea syndromes. In a sample of 25 consecutive male sleep apneics, 40% met Research Diagnostic Criteria for an affective disorder or for alcohol abuse. A multiple regression analysis indicated that 61% of the variance in depression ratings could be explained by four variables: age, REM activity, REM latency (square root), and presence or absence of antihypertensive medications (multiple R = 0.78). The use of these variables in a discriminant function analysis correctly predicted the membership of 68% of the sample in either a low or high depression group (kappa = 0.44; p less than .01). These findings are reviewed in relation to other research on age-related sleep changes and vulnerability to depression.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D011336:Probability; D011569:Psychiatric Status Rating Scales; D012737:Sex Factors; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000523:psychology*; D012895:Sleep, REM / Q000502:physiology
chemical_list: D000959:Antihypertensive Agents