[Indices of oxygen supply to the bodies of rats following blood replacement by a perfluorodecalin emulsion].
Complete exchange blood replacement by perfluorodecalin (PFD) emulsion containing 20 v% PFD, 5 w% polyoxyethylene-polyoxypropylene block copolymer as a surfactant and saline solution as a salt medium was performed in rats. The parameters of oxygen supply to the body in the initial state and at hematocrit levels decreased to 10, 5 and 1% were studied. It has been shown that oxygen consumption at the expense of PFD emulsion can reach values comparable with the initial ones.
D000818:Animals; D001775:Blood Circulation; D001802:Blood Substitutes / Q000008:administration & dosage; D002245:Carbon Dioxide / Q000032:analysis; D004655:Emulsions; D005466:Fluorocarbons / Q000008:administration & dosage; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D010108:Oxyhemoglobins / Q000032:analysis; D051381:Rats
D001802:Blood Substitutes; D004655:Emulsions; D005466:Fluorocarbons; D010108:Oxyhemoglobins; D002245:Carbon Dioxide; C008805:perfluorodecalin; D010100:Oxygen
Izuchenie pokazateleĭ kislorodnogo snabzheniia organizma krys pri obmennom zameschenii krovi émul'sieĭ perftordekalina.