Monoacylcadaverines as substrates for both monoamine oxidase and diamine oxidase; low rates of activity.
Monoacetylcadaverine and monopropionylcadaverine were found to be substrates for both rat liver monoamine oxidase and hog kidney diamine oxidase, but all the Km-values for the oxidases were very high. The amines were common substrates for type A and type B monoamine oxidase.
D006631:Amine Oxidase (Copper-Containing) / Q000037:antagonists & inhibitors*; D000818:Animals; D002103:Cadaverine / Q000031:analogs & derivatives; D003010:Clorgyline / Q000494:pharmacology; D003959:Diamines; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D008930:Mitochondria, Liver / Q000201:enzymology; D008995:Monoamine Oxidase / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors; D010293:Pargyline / Q000494:pharmacology; D051381:Rats; D012642:Selegiline / Q000494:pharmacology; D013379:Substrate Specificity; D013552:Swine
D003959:Diamines; D008996:Monoamine Oxidase Inhibitors; D012642:Selegiline; C025476:monoacetylcadaverine; C025477:monopropionylcadaverine; D010293:Pargyline; D006631:Amine Oxidase (Copper-Containing); D008995:Monoamine Oxidase; D002103:Cadaverine; D003010:Clorgyline