Polar encapsidation of adenovirus DNA: cloning and DNA sequence of the left end of adenovirus type 3.
The left-end adenovirus type 3 DNA sequence is very similar to those of other subgroup B adenoviruses, especially in the area between the HinfI site (320 base pairs) and the early-region Ia gene. This segment of the genome has been implicated as necessary for the left-end polarity of adenovirus DNA encapsidation. This segment and the sequences flanking it are compared with the corresponding sequences of adenovirus type 5 and adenovirus type 12, and the extent and pattern of intersubgroup homologies are discussed.
D000260:Adenoviruses, Human / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D002213:Capsid / Q000378:metabolism; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics* / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D005814:Genes, Viral; D009024:Morphogenesis; D010957:Plasmids
D004279:DNA, Viral