Delay and inhibition of growth of Neisseria gonorrhoeae in vitro. Relationship of delayed incubation, penicillinase production, urine culture, and self-treatment.
Delay in the appearance of Neisseria gonorrhoeae on Thayer-Martin medium was associated with delay in incubation and with the use of urine samples from infected men for cultural diagnosis. Self-treatment among women was related to inhibition of growth of N gonorrhoeae, particularly of non-penicillinase-producing gonococci (beta-lactamase). The difference in the time of appearance of penicillinase-producing and non-penicillinase-producing gonococci was significant in men but not in women.
D000818:Animals; D002584:Cervix Uteri / Q000382:microbiology; D005260:Female; D008297:Male; D008828:Microbiological Techniques; D009344:Neisseria gonorrhoeae / Q000201:enzymology / Q000254:growth & development*; D010405:Penicillinase / Q000096:biosynthesis*; D012651:Self Medication; D013045:Species Specificity; D013997:Time Factors; D014521:Urethra / Q000382:microbiology; D014556:Urine / Q000382:microbiology*; D001618:beta-Lactamases / Q000096:biosynthesis*
D010405:Penicillinase; D001618:beta-Lactamases