Iodine-enhanced CT patterns after cerebral arterial embolization in baboons.
The pathophysiology of iodine-enhanced computed tomography (CT) patterns produced by embolic arterial cerebral infarction in the baboon is reported. The appearance of iodine patterns in zones of nonperfusion, blood-brain barrier damage, loss of autoregulation, and neovascularity is demonstrated. The iodine CT patterns were correlated with stable xenon CT flow studies, regional cerebral blood flow studies, clinical course, and pathology.
D000818:Animals; D001812:Blood-Brain Barrier; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine; D004195:Disease Models, Animal; D010215:Papio; D014057:Tomography, X-Ray Computed / Q000379:methods*
D003973:Diatrizoate; D003974:Diatrizoate Meglumine