Bioassay for determination of vancomycin in the presence of rifampin or aminoglycosides.
Vancomycin determinations were performed in the presence of an aminoglycoside or rifampin. A previously reported bioassay method was modified by using a rifampin-resistant strain and increasing the NaCl concentration in the minimal salts-glucose assay agar from 0.2 to 6.0%.
D000617:Aminoglycosides / Q000032:analysis*; D001412:Bacillus subtilis / Q000187:drug effects; D001681:Biological Assay / Q000379:methods*; D004357:Drug Synergism; D008828:Microbiological Techniques; D012293:Rifampin / Q000032:analysis*; D014640:Vancomycin / Q000032:analysis*
D000617:Aminoglycosides; D014640:Vancomycin; D012293:Rifampin