Cross-reactions between protamines of different species: the role of arginine clusters.
Human and monkey sera containing autoantibodies to protamines reveal often strong cross-reactions with protamines of other species including salmon protamine. These cross-reactions can be readily detected both in the immunofluorescence test and th micro-complement fixation test. These sera react to a much lesser extent with poly-L-arginine. The results indicate that the cross-reactions of these protamines are not primarily due to clusters of arginine.
D000818:Animals; D001120:Arginine / Q000276:immunology*; D001323:Autoantibodies; D002417:Cattle; D003168:Complement Fixation Tests; D003429:Cross Reactions; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D000882:Haplorhini; D006801:Humans; D011479:Protamines / Q000276:immunology*; D012474:Salmon
D001323:Autoantibodies; D011479:Protamines; D001120:Arginine