[An ultrastructural immunocytochemical study of secretory granules of an adenohypophyseal tumor].
The unlabeled antibody peroxidase-antiperoxidase complex technique was used to stain for electron microscopy the secretory granules of a pituitary tumor that had been surgically removed from a woman with high serum prolactin levels. Granules were stained using anti-human prolactin serum. The diameter of the secretory granules was smaller than that measured for the granules of prolactin producing cells in normal human pituitary glands. A shortened storage phase would explain the diameter reduction.
D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008854:Microscopy, Electron; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure; D010911:Pituitary Neoplasms / Q000648:ultrastructure*; D011388:Prolactin / Q000097:blood
D011388:Prolactin
Studio immunocitochimico ultrastrutturale sui granuli di secrezione di un tumore adenoipofisario.