Absence of lesions in the hypothalamus of frogs treated with gold thioglucose.
Gold thioglucose (800-1000 mg/kg ip) failed to cause lesions in the hypothalamus of Rana pipiens within 48 h of injection. Since this dose is a pharmacological one in mammals it is likely that the frog hypothalamus differs significantly in its sensitivity.
D000818:Animals; D006051:Aurothioglucose / Q000494:pharmacology*; D005247:Feeding Behavior / Q000502:physiology; D006046:Gold / Q000494:pharmacology*; D007031:Hypothalamus / Q000187:drug effects* / Q000473:pathology; D009336:Necrosis / Q000139:chemically induced; D011894:Rana pipiens / Q000502:physiology*
D006051:Aurothioglucose; D006046:Gold