Ineffectiveness of testosterone and FSH in maintaining the vitamin A deficient rat testis.
The combined administration of follicle-stimulating hormone and testosterone to sexually mature male rats whose testes were in the early stages of damage from retinol deficiency did not prevent the continued degeneration of the germinal epithelium. It is concluded that the action of retinol on the testis is probably not mediated through, nor influenced by, the pituitary or steroid hormones.
D000818:Animals; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage*; D008297:Male; D051381:Rats; D013094:Spermatozoa / Q000187:drug effects; D013733:Testicular Diseases / Q000188:drug therapy* / Q000209:etiology; D013737:Testis / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage*; D014212:Tretinoin / Q000494:pharmacology; D014802:Vitamin A Deficiency / Q000150:complications / Q000188:drug therapy*
D013739:Testosterone; D014212:Tretinoin; D005640:Follicle Stimulating Hormone