Microencapsulated islets as bioartificial endocrine pancreas.
Single implantation of microencapsulated islets into rats with streptozotocin-induced diabetes corrected the diabetic state for 2 to 3 weeks. The microencapsulated islets remained morphologically and functionally intact throughout long-term culture studies lasting over 15 weeks.
D000464:Alginates / Q000627:therapeutic use*; D000818:Animals; D002470:Cell Survival; D003921:Diabetes Mellitus, Experimental / Q000628:therapy*; D016381:Islets of Langerhans Transplantation; D010539:Permeability; D051381:Rats; D014184:Transplantation, Homologous
D000464:Alginates