Radiographic and angiographic changes in osteosarcoma after intraarterial chemotherapy.
Transcatheter arterial infusion has improved the preoperative control of osteosarcoma. The conventional radiographs and angiograms of osteosarcoma were evaluated in 53 patients before and after treatment. In the responders, two types of calcifications representing healing are observed: peripheral and central. The calcification is readily differentiated from that of tumor new bone. Angiography revealed a decrease in tumor vascularity and stain in responding tumors. Excellent angiographic and pathologic correlation of these changes is presented.
D000792:Angiography; D001859:Bone Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002945:Cisplatin / Q000627:therapeutic use*; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006652:Histological Techniques; D006801:Humans; D007261:Infusions, Intra-Arterial; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013977:Tibia / Q000000981:diagnostic imaging; D013997:Time Factors
D002945:Cisplatin