Cyclic oscillations in leukocyte count in chronic myeloid leukemia.
Cyclic oscillations in the leukocyte count were observed on 14 occasions in 9 out of 70 cases of chronic myeloid leukemia. Importance of this knowledge lies in minimising the total amount of drug therapy and avoiding frequent unnecessary alterations in the dose schedule.
D001683:Biological Clocks; D002066:Busulfan / Q000627:therapeutic use; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D007951:Leukemia, Myeloid / Q000097:blood / Q000188:drug therapy; D007958:Leukocyte Count
D002066:Busulfan; D006918:Hydroxyurea