[Effect of the in vitro ultraviolet irradiation of autogenous blood on hematological, biochemical and biological indices in sheep with experimentally induced sepsis].
Studies were carried out with 10 sheep infected with a 24th hour broth culture of strain 1088 of Corynebacterium pyogenes. The animals were divided into two groups of 5 each--control and test. Autotransfusion of untreated blood was carried out with the control group, and autotransfusion of UV-treated (in vitro) blood--with the test group. Used was a M-LK5 type lamp, and irradiation lasted 10 min. The autotransfusion of both treated and untreated blood was well tolerated by the sheep. It did not cause deviations from the normal clinical indices. It was established that the autohemotransfusion with untreated blood did not bring about changes in reactions that could be clinically followed up in the course of the disease. On the other hand, the autohemotransfusion of blood that was treated in vitro with ultra-violet rays had a beneficial effect on the body as a whole and on the individual clinical indices.
D000818:Animals; D001769:Blood / Q000528:radiation effects; D001773:Blood Cells / Q000528:radiation effects; D001804:Blood Transfusion, Autologous / Q000662:veterinary*; D003354:Corynebacterium Infections / Q000628:therapy / Q000662:veterinary*; D003355:Corynebacterium pyogenes; D066298:In Vitro Techniques; D010587:Phagocytosis / Q000528:radiation effects; D018805:Sepsis / Q000628:therapy / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000628:therapy*; D013997:Time Factors; D014467:Ultraviolet Therapy / Q000662:veterinary*
Vliianie na oblŭchenata s ultravioletovi lŭchi in vitro autogenna krŭv vŭrkhu niakoi khematologichni, biokhimichni i biologichi pokazateli pri ovtse s eksperimentalno predizvikan sepsis.