A clinical trial of hyperalimentation in children with metastatic malignancies.
In a controlled, randomized prospective clinical trial the utility of intravenous hyperalimentation (IVH) in the administration of and tolerance to chemotherapy was tested. The conclusions reached were 1) IVH is safe with a tolerable infection rate; 2) infectious complications correlate significantly with the nutritional status of the patient, with the presence of IVH being only a secondary factor; 3) IVH may be used to rehabilitate patients nutritionally, even those on intensive chemotherapy; 4) the ability to deliver chemotherapy to patients seems to be improved by IVH, especially in malnourished patients in a late stage of disease.
D000970:Antineoplastic Agents / Q000008:administration & dosage; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007239:Infections / Q000209:etiology; D008297:Male; D009362:Neoplasm Metastasis / Q000628:therapy*; D010288:Parenteral Nutrition / Q000009:adverse effects; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D011446:Prospective Studies
D000970:Antineoplastic Agents