[Paradoxical ventilatory response of babies to pure oxygen (author's transl)].
In order to determine indicators for the risk of SIDS (sudden infant death syndrome) the respiratory responses of babies (age 1 to 5 months) during sleep to various gas mixtures was examined. Using a face mask combined with a pneumotachograph in all cases a marked increase of the ventilation was found, when the babies were exposed to pure oxygen. Furthermore, the response of the babies to the exposure to mild hypoxia was tested. In 24 out of 36 babies a ventilatory depression was observed which sometimes was coupled with periodic or arrhythmic ventilation. These paradox reactions--depression by mild hypoxia and stimulation by hyperoxia--might be related to a possible circulus vitiosus in the pathogenesis of SIDS.
D002245:Carbon Dioxide / Q000378:metabolism; D006801:Humans; D007223:Infant; D010101:Oxygen Consumption; D012119:Respiration; D012129:Respiratory Function Tests; D012890:Sleep; D013398:Sudden Infant Death / Q000503:physiopathology*
D002245:Carbon Dioxide
Paradoxe Atemantwort von Säuglingen auf Sauerstoff.