[The role of automyelotransfusion (AMT) in total body irradiation of disseminated neoplasms. Prospects of physical and biological modulation of the dose].
Many experimental data concerning radioprotection and radiosensitization by drugs may become useful guidelines for the treatment of generalized malignancies by TBI/HBI. Moreover, automyelotransfusion as a powerful radioprotective measure, together with a selective individual lead shielding system of sensitive tissues and organs can lead to the realization of a physical and biological modulation of the dose, as a basis for a useful therapeutic ratio between disseminated tumors and healthy tissues.
D016026:Bone Marrow Transplantation; D006801:Humans; D007854:Lead; D009369:Neoplasms / Q000532:radiotherapy*; D011481:Protective Clothing; D011835:Radiation Protection / Q000379:methods*; D011837:Radiation-Protective Agents / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D014182:Transplantation, Autologous; D014916:Whole-Body Irradiation
D011837:Radiation-Protective Agents; D007854:Lead
Ruolo dell'automielotrasfusinoe (AMT) nella irradiazione corporea totale delle neoplasie disseminate. Prospettive di modulazione fisica e biologica della dose.