The early enzymatic debridement and grafting of deep dermal burns to the hand.
Thirty-four hands in 24 patients with clinically diagnosed, deep second-degree burns have been treated for 24 hours, immediately after the burn with Sutilains bacterial enzymatic ointment. The ages of the patients range from 16 months to 65 years. Follow-up was from 3 to 12 months. After 24 hours' treatment with the enzyme, the patient is taken to the operating room, where the soft eschar is scraped from the wound and thin split-thickness grafts are applied. Ninety-one percent had full take of the grafts and were able to move their hands actively and passively through a full range of movement within 1 week after the burn. The long-term aesthetic and functional results were excellent.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001412:Bacillus subtilis / Q000201:enzymology; D001458:Bandages; D002056:Burns / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003646:Debridement / Q000379:methods*; D005069:Evaluation Studies as Topic; D005343:Fibrinolytic Agents; D006230:Hand Injuries / Q000601:surgery*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D009824:Ointments; D010447:Peptide Hydrolases / Q000008:administration & dosage; D011300:Preoperative Care / Q000379:methods; D016038:Skin Transplantation; D013997:Time Factors; D014182:Transplantation, Autologous
D005343:Fibrinolytic Agents; D009824:Ointments; D010447:Peptide Hydrolases