Keratitis due to Aspergillus flavus successfully treated with thiabendazole.
A case of Aspergillus flavus keratitis treated successfully with 4% suspension of thiabendazole is reported. This seems to be the first case of successful treatment of keratomycosis with thiabendazole. All other reported cases treated with this drug either had their eyes removed or did not retain any useful vision. Its ability to penetrate ocular tissues, ability to remain in concentrations higher than the minimal inhibitory concentration of many fungi, and broad spectrum of activity make it a worthwhile drug for further investigation in keratomycosis.
D000328:Adult; D001228:Aspergillosis / Q000188:drug therapy*; D001231:Aspergillus flavus; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D013827:Thiabendazole / Q000627:therapeutic use*
D013827:Thiabendazole