Reduction of post-prandial insulin needs by pectin as assessed by the artificial pancreas in insulin-dependent diabetics.
The efficacy of a moderate amount (7 grams) of apple pectin in diminishing post-prandial insulin needs in insulin dependent diabetics (IDD) has been tested using an artificial pancreas in a sequential analysis. With this method, only four patients who served as their own control, showed significant reductions in insulin requirement of 3 Iu with pectin after a 60 g carbohydrate mixed meal. The use of pectin cut by 35 per cent the post prandial insulin demand. The patients judged the treatment as acceptable. More prolonged use in IDD is advisable.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D004435:Eating; D005260:Female; D006801:Humans; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010368:Pectins / Q000627:therapeutic use*
D001786:Blood Glucose; D007328:Insulin; D010368:Pectins