Studies on new phosphonic acid antibiotics. III. Isolation and characterization of FR-31564, FR-32863 and FR-33289.
Three phosphonic acid antibiotics were found to be produced in the fermentation broths of Streptomyces. FR-31564 and FR-32863 were produced by Streptomyces lavendulae. FR-33289 was produced by a strain of Streptomyces, identified as Streptomyces rubellomurinus subsp. indigoferus. They are distinct from, but resemble FR-900098 which was reported in our preceding paper, in their chemical and biological characteristics.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003470:Culture Media; D004754:Enterobacter / Q000187:drug effects; D005285:Fermentation; D005578:Fosfomycin / Q000031:analogs & derivatives / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013302:Streptomyces / Q000032:analysis
D000900:Anti-Bacterial Agents; D003470:Culture Media; D005578:Fosfomycin; C024640:fosmidomycin; C024641:FR 32863; C024642:FR 33289