Evaluation of baboon antiserum to carcinoembryonic antigen.
The common baboon (Papio), immunized with carcinoembryonic antigen (CEA), was found to form specific-site antibodies for CEA. The baboon antiserum does not recognize colon carcinoma antigen-III, but does demonstrate similar ionic strength effects to those previously described for goat antisera to the CEA-specific site(s). Baboon specific-site antibody for CEA can be used for radioimmunoassay of CEA in plasma and gives similar results to the commercial (Roche) goat anti-CEA.
D000818:Animals; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D003110:Colonic Neoplasms / Q000276:immunology; D006041:Goats / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D005779:Immunodiffusion; D010215:Papio / Q000276:immunology
D002272:Carcinoembryonic Antigen; D007106:Immune Sera