[Specific immunologic stimulation induced by cryosurgery of spinocellular tumors & of the oral cavity].
In previous works the Authors have shown that cryosurgical treatment of oral squamous cell cancer modifies numerous aspecific immunological parameters mostly concerning the cell-mediated component. In the present work the Authors have studied the leukocyte migration inhibition (LMI) response in vitro of peripheral blood leukocytes from patients affected by oral squamous cancer to oral tumor antigens using the leukocyte migration agarose test. The LMI was evaluated immediately before cryosurgical treatment of oral squamous cell carcinoma and 7 and 14 days after. The results suggest that cryosurgery is able to stimulate the specific cell-mediated response of patients affected by early stage carcinoma of oral cavity.
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000601:surgery; D003452:Cryosurgery; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007961:Leukocyte Migration-Inhibitory Factors / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology* / Q000601:surgery
D007961:Leukocyte Migration-Inhibitory Factors
Stimolazione immunitaria specifica indotta da criochirurgia in tumori spinocellulari del cavo orale.