[Importance of the immotile cilia syndrome in E.N.T. field].
Associated with nasal secretion, the ciliary activity establish the first line of defense of respiratory mucosa. The primary pathology of the ciliary structures is not well known. Correlated with testing of the mucociliary transport, only the ultrastructural study could open this very interesting field. With a short review of the present status of the ineffective mucociliary clearance mechanisms, 9 new cases of immotile cilia syndrome, with or without situs inversus, are studied. Actually, the following anomalies seems to be significant : lack of one or two dyneïn arms, confusion of the central doublets' axis, ciliary roots anomalies. Despite that more information is needed, a good knowledge of this genetic errors is henceforth necessary for clinical and therapeutical applications especially to avoid undue surgical treatments.
D000328:Adult; D002648:Child; D002923:Cilia / Q000502:physiology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007619:Kartagener Syndrome / Q000473:pathology; D008297:Male; D008858:Microscopy, Phase-Contrast; D010038:Otorhinolaryngologic Diseases / Q000209:etiology*; D013577:Syndrome
L'intérêt du syndrome d'immotilité ciliaire en O.R.L.