Granulocytic sarcoma of the brain after renal transplantation.
A case of granulocytic sarcoma of the brain in a renal transplant recipient treated with immunosuppressive agents is presented. While the increased risk of malignant lymphoma, particularly large-cell lymphoma (reticulum cell sarcoma, histiocytic lymphoma, immunoblastic sarcoma) in these patients is well known, this appears to be the first report of a granulocytic sarcoma. Granulocytic sarcoma, a rare tumor composed of immature granulocytic elements, almost never involves the parenchyma of the brain. Histochemical examination may be necessary to distinguish this lesion from other poorly-differentiated neoplasms.
D000328:Adult; D001921:Brain / Q000473:pathology / Q000648:ultrastructure; D001932:Brain Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D007951:Leukemia, Myeloid / Q000473:pathology* / Q000648:ultrastructure