[The influence of L-dopa and of thymus fraction on the survival rate of whole-body-irradiated mice].
The survival rate of mice with exposure of the whole body (700 cGy) was hardly changed by one dose as well as several doses of the phosphodiesterase inhibitor Amantadine and the interferon inductor measles vaccine. However, the survival rates were increased by one administration of L-dopa or by the long-term therapy using L-dopa at 700 and 900 cGy. The survival rates were also increased at 700 and 900 cGy if, after the exposure, thymus factor isolated from calf thymus was three times applied to the animals. The increased survival rates gained by using L-dopa and thymus factor are correlated with the determined leukocyte values.
D000547:Amantadine / Q000494:pharmacology; D000818:Animals; D007980:Levodopa / Q000494:pharmacology*; D008297:Male; D008458:Measles Vaccine / Q000494:pharmacology; D051379:Mice; D013935:Thymic Factor, Circulating / Q000494:pharmacology*; D013951:Thymus Hormones / Q000494:pharmacology*; D014916:Whole-Body Irradiation / Q000401:mortality*
D008458:Measles Vaccine; D013951:Thymus Hormones; D007980:Levodopa; D013935:Thymic Factor, Circulating; D000547:Amantadine
Der Einfluss von L-Dopa und Thymusfraktion auf die Uberlebensrate ganzkörperbestrahlter Mäuse.