Mucopolysaccharidase activity in traumatized human deciduous teeth undergoing accelerated resorption: isolation and characterization.
Mucopolysaccharidase activity was observed in traumatized human decidous teeth. Histochemical analysis of the periodontal ligaments from these teeth revealed a loss of film substrate metachromasia during incubation, indicating enzyme activity. Routine histology of these ligaments showed the presence of an inflammatory infiltrate throughout this tissue. Biochemical analysis of the ligaments revealed a 10-fold increase of enzyme activity when incubation time was increased from 1 to 8 h. When compared to the enzyme activity measured during physiologic resorption, activity was increased. This suggests that the presence of an inflammatory infiltrate not observed in the tissues undergoing physiologic resorption may be responsible for the rapid resorption seen in traumatized deciduous teeth.
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000302:isolation & purification / Q000378:metabolism*; D008297:Male; D010513:Periodontal Ligament / Q000201:enzymology; D010518:Periodontitis / Q000201:enzymology; D014091:Tooth Resorption / Q000201:enzymology*; D014094:Tooth, Deciduous / Q000201:enzymology* / Q000293:injuries
D006821:Hyaluronoglucosaminidase