Descending luteinizing hormone-releasing hormone (LH-RH) nerve fibers to the midbrain of the rat.
Using the peroxidase-antiperoxidase complex (PAP) immunohistological method, a luteinizing hormone-releasing hormone (LH-RH)-containing nerve fiber tract was detected in the mesencephalon of intact rats, and in rats bearing a symmetrical cut in the coronal plane at the level of the superior collicle reaching down to the ventral tegmental decussation. This LH-RH fiber tract was found in subependymal position in the mesencephalic central gray. The LH-RH fibers reached the ponto-mesencephalic junction in the intact animals, whereas in the experimental group they were absent behind the cut. These findings indicated that the direction of the LH-RH axons in the mesencephalic central gray is descending.
D000818:Animals; D004525:Efferent Pathways / Q000502:physiology; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000502:physiology*; D008636:Mesencephalon / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology*; D051381:Rats / Q000502:physiology*; D012726:Sexual Behavior, Animal / Q000502:physiology
D007987:Gonadotropin-Releasing Hormone