[Experimental testing of a rodenticidal preparation, Pyriminyl (Vacor), in small animals].
The toxicity of the rodenticidal product Pyriminyl (Vacor) was tested in 4 dogs, 9 cats, 11 coypus and 16 ducks. In the tested dogs the 1000mg dose per kg l. w. was lethal only in 17% of cases. The results demonstrate that the LD50 for the dog is higher than stated in the literature (1000 mg/kg l. w.). Dogs show a high variability in their sensitivity to the product, since some of them died at lower doses. It can be assumed that 1 to 2% field bait will not induce any lethal intoxication in dogs. Doses of 300 mg/kg l. w. and higher were lethal for cats. The dose of 200 mg/kg killed 66% of the cats tested. There is a high possibility of poisoning cats in field deratization campaigns with Vacor. Coypus show clinical symptoms of intoxication after ingesting a Vacor bait at a 100mg dose per kg l. w.; however, they remain alive. Doses of 300 mg/kg l. w. and higher kill all the animals tested. The high sensitivity of coypu to Vacor suggests that coypu can be poisoned during Vacor deratization of coypu farms. Ducks were highly resistant to Vacor. Doses from 710 to 3000 mg per kg l. w. were endured without clinical changes, and the same was the case when the birds were given a diet with a 2% concentration of Vacor for six days. The toxicological examination demonstrated the different amounts of Vacor in liver for different periods of time from the ingestion of the toxic agent, including the dependence on the animal species.
D000818:Animals; D002415:Cats; D004285:Dogs; D004372:Ducks; D010671:Phenylurea Compounds / Q000633:toxicity*; D012377:Rodentia; D012378:Rodenticides / Q000633:toxicity*
D010671:Phenylurea Compounds; D012378:Rodenticides; C012598:pyriminil
Experimentální ovĕrenĭ rodenticidního prípravku Pyriminyl (Vacor) u malých zvírat.