[In vivo voltametric measurement of ascorbic acid and DOPAC in the striatum of the rat and guinea-pig].
Differential pulse voltammetry was performed with electrochemically treated carbon fiber electrodes. By this technique, ascorbic acid and catechol compounds were resolved in vitro in two distinct peaks. Similar oxidation peaks were obtained in vivo from the striatum of Rats and Guinea-Pigs. From electrochemical and pharmacological observations it is suggested that they correspond to the oxidation of extracellular ascorbic acid and 3,4-dihydroxyphenyl acetic acid (DOPAC).
D015102:3,4-Dihydroxyphenylacetic Acid / Q000032:analysis*; D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis*; D002396:Catechols / Q000032:analysis; D003342:Corpus Striatum / Q000032:analysis*; D004563:Electrochemistry; D006168:Guinea Pigs; D008297:Male; D008722:Methods; D008839:Microelectrodes; D010084:Oxidation-Reduction; D010648:Phenylacetates / Q000032:analysis*; D051381:Rats
D002396:Catechols; D010648:Phenylacetates; D015102:3,4-Dihydroxyphenylacetic Acid; D001205:Ascorbic Acid
Mesure voltamétrique in vivo de l'acide ascorbique et du DOPAC dans le striatum du rat et du cobaye.