Transluminal angioplasty of renal artery stenosis: 70 experiences.
Percutaneous transluminal angioplasty was attempted in 70 stenotic renal arteries using the balloon angioplasty technique described by Grüntzig for peripheral vessels. There were 58 patients with normal renal function and 12 with decreased renal function. Dilatation of the stenosis was initially successful in 65 attempts and unsuccessful in five. Four of the stenoses became restenosed; two were successfully dilated a second time. Complications occurred in four patients; three developed acute tubular necrosis and one sustained an inconsequential renal artery dissection. Patients with renin-dependent hypertension had dramatic reduction in blood pressure in most instances; 90% were cured or improved. Other hypertensive patients without demonstrable renin dependency had less marked reduction, but were often benefited. Patients with hypertension and renal failure were helped to a lesser extent.
D001027:Aortography; D001794:Blood Pressure; D002404:Catheterization / Q000009:adverse effects / Q000379:methods*; D004106:Dilatation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D012083:Renin / Q000032:analysis; D012306:Risk
D012083:Renin