[A cell line particularly susceptible to bovine enteric Coronavirus replication: HRT 18 cells].
Bovine enteric Corona virus (BEC) multiplies spontaneously with very high efficiency in HRT 18 cells; this line established from human rectum adenocarcinoma presents some properties of the differentiated brush border cell of the intestinal villi. Titers obtained are very high (5 x 10(7) TCID 50/ml virus strain F15). The virus produced had the characteristic of BEC: shape, spikes, density 1.19, hemadsorption and hemagglutination of rat erythrocytes. Human and dog enteritic corona viruses replicate also in HRT 18 cells.
D000230:Adenocarcinoma; D000818:Animals; D002417:Cattle; D002460:Cell Line; D003332:Coronaviridae / Q000254:growth & development* / Q000648:ultrastructure; D004285:Dogs; D006387:Hemagglutination, Viral; D006801:Humans; D008871:Microvilli / Q000382:microbiology; D051381:Rats; D012004:Rectal Neoplasms; D014776:Virus Cultivation; D014779:Virus Replication
Une lignée cellulaire particulièrement sensible à la réplication du Coronavirus entéritique bovin : les cellules HRT 18.