Positive two-stage carcinogenesis in female Sprague-Dawley rats using 7,12-dimethylbenz(a)anthracene (dmba) as initiator and 12-o-tetradecanoylphorbol-13-acetate (tps) as promotor. Results of a pilot study.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology*; D000287:Administration, Topical; D000818:Animals; D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D002369:Castration; D003043:Cocarcinogenesis; D003110:Colonic Neoplasms / Q000139:chemically induced; D005260:Female; D007414:Intestinal Neoplasms / Q000139:chemically induced; D008113:Liver Neoplasms / Q000139:chemically induced; D010704:Phorbols / Q000494:pharmacology*; D051381:Rats; D012878:Skin Neoplasms / Q000139:chemically induced; D013270:Stomach; D013274:Stomach Neoplasms / Q000139:chemically induced; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*
D001551:Benz(a)Anthracenes; D010704:Phorbols; D015127:9,10-Dimethyl-1,2-benzanthracene; D013755:Tetradecanoylphorbol Acetate