The embryology and endocrinology of primary amenorrhoea: a study of one hundred and forty patients.
The overwhelming majority of girls presenting with primary amenorrhoea have aetiologies with their roots in disturbances of embryogenesis and/or the endocrinology of sexual differentiation. This review will deal with the fundamentals of embryology and endocrinology relevant to the subject and then discuss the findings in a group of one hundred and forty patients with primary amenorrhoea as they relate to these disturbances.
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000150:complications; D000367:Age Factors; D000568:Amenorrhea / Q000209:etiology*; D054304:Anti-Mullerian Hormone; D002988:Cloaca / Q000196:embryology; D012734:Disorders of Sex Development / Q000150:complications*; D005260:Female; D005836:Genitalia, Female / Q000196:embryology; D006023:Glycoproteins; D006131:Growth Inhibitors; D006182:H-Y Antigen / Q000235:genetics; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D009095:Mullerian Ducts; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D011627:Puberty; D013735:Testicular Hormones; D013737:Testis / Q000196:embryology; D014599:Uterus / Q000002:abnormalities; D014621:Vagina / Q000002:abnormalities
D006023:Glycoproteins; D006131:Growth Inhibitors; D006182:H-Y Antigen; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone; D011388:Prolactin