Decrease in serum free triiodothyronine, thyroxine-binding globulin and thyroxine-binding prealbumin whilst taking a very-low-calorie diet.
Serum free triiodothyronine decreased significantly (P < 0.02) by 18 per cent (range from -8 to +47 per cent) in 13 grossly obese patients after 11 days (median) treatment (range 8-18 days) with a very-low-calorie diet consisting of 43.0 g protein, 30.4 g carbohydrate and 1.1 g lipid. Also a significant decrease was found in serum total triiodothyronine (P < 0.007), thyroxine-binding globulin (P < 0.008) and thyroxine-binding prealbumin (P < 0.005). No significant changes in serum free thyroxine, total thyroxine and TSH could be demonstrated.
D000328:Adult; D004038:Diet, Reducing; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy*; D011228:Prealbumin / Q000032:analysis*; D012709:Serum Albumin / Q000032:analysis*; D012712:Serum Globulins / Q000032:analysis*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000032:analysis; D014284:Triiodothyronine / Q000097:blood*
D011228:Prealbumin; D012709:Serum Albumin; D012712:Serum Globulins; D013975:Thyroxine-Binding Proteins; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine