[Effect of antibiotics and bifiodobacterium preparations on the intestinal microflora of mice irradiated with gamma quanta].
The treatment of CBA mice, irradiated in a dose of 700 Gy with antibiotics (penicillin V, oxytetracycline, streptomycin) in combination with bacterial therapy (B. bifidum, strain 75-41) or with antibiotics alone led to the increased percentage of survivors among them in comparison with the control animals. At the same time the medical prognosis was better in cases of the combined treatment with antibiotics and bifidobacteria. This circumstance was due to the fact that the combined treatment with antibiotics and bifidobacteria, considerably facilitated the normalization of the microbial picture of the intestine; in this case the "eubiosis" of the intestinal tract was almost completely restored by the 22nd day after the irradiation, whereas in the treatment with antibiotics alone the inhibitory effect on the development of the opportunistic flora at a later period of the development of dysbacteriosis was less pronounced, while the number of lactic acid bacteria remained at the same low level as in the untreated mice.
D000191:Actinomycetaceae; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001688:Biological Products / Q000627:therapeutic use*; D005720:Gamma Rays; D007422:Intestines / Q000382:microbiology / Q000528:radiation effects*; D051379:Mice; D008808:Mice, Inbred CBA; D010118:Oxytetracycline / Q000627:therapeutic use; D010404:Penicillin V / Q000627:therapeutic use; D011833:Radiation Injuries, Experimental / Q000628:therapy*; D013307:Streptomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D001688:Biological Products; D010118:Oxytetracycline; D013307:Streptomycin; D010404:Penicillin V
Vliianie antibiotikov i preparatov bifidobakterii na mikrofloru kishechnika myshei, obluchennykh gamma-kvantami.