Comparison of fluorescent immunoassay (FIA) and enzyme-multiplied immunoassay technique (EMIT) for measurement of serum carbamazepine concentration.
The recently developed fluorescent immunoassay (FIA) for measuring serum carbamazepine concentration is compared to the established enzyme-multiplied-immunoassay-technique (EMIT). The Accuracy, precision and simplicity of these methods are comparable. The sensitivity of FIA is approximately eight times greater than the EMIT but the assay time required for FIA is longer. Potential improvements of the FIA technique are discussed.
D002220:Carbamazepine / Q000097:blood*; D005455:Fluorescent Antibody Technique; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D007124:Immunoenzyme Techniques; D012044:Regression Analysis
D002220:Carbamazepine; D006493:Heparin