The antitumor action of bacterial extracts. II. Suppressive effects of extracts of E. coil on subcutaneous tumors of mouse.
Subsequent to the previous report showing that the French pressure cell extract of E. coli exhibited a marked antitumor effect against several ascites tumors in the mouse, it has been demonstrated presently that the extract and the proteinous fraction obtained from cells of E. coli exert a definite suppressive effect against subcutaneous solid form tumors of mouse including young generation transplants of spontaneous mammary carcinoma arisen in C3H/He mice. However, occasional enhanced growth brought about by similar treatments left an important problem unsolved.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000628:therapy*; D004926:Escherichia coli / Q000276:immunology*; D007167:Immunotherapy; D008325:Mammary Neoplasms, Experimental / Q000628:therapy*; D051379:Mice; D008809:Mice, Inbred C3H; D008815:Mice, Inbred Strains; D012513:Sarcoma, Experimental / Q000628:therapy*