[Antigenic properties of the allergoid from ragweed pollen].
It was shown that allergoid, a preparation with decreased allergenicity and preserved immunogenicity, can be produced from ragweed growing in Stavropol. A comparative study of variations in the antigenic properties of the allergen under the effect of the temperature factor alone or a combination of the latter with formaldehyde allowed a conclusion that formaldehyde selectively neutralizes the antigenic determinants responsible for allergenicity. At the same time allergoid preserves its ability to induce antibody specific for the initial allergen in the rabbit.
D000485:Allergens / Q000032:analysis*; D000080384:Allergoids; D000941:Antigens / Q000032:analysis*; D005557:Formaldehyde / Q000276:immunology; D005779:Immunodiffusion; D010936:Plant Extracts / Q000032:analysis*; D011058:Pollen / Q000276:immunology*; D013696:Temperature; D013997:Time Factors
D000485:Allergens; D000080384:Allergoids; D000941:Antigens; D010936:Plant Extracts; D005557:Formaldehyde
Izuchenie antigennykh svoĭstv allergoida iz pyl'tsy ambrozii.