Factor VII survival studies in factor VII Padua abnormality.
Two patients with factor VII Padua abnormality were studied during prophylactic administration of factor VII concentrates for tooth extractions. The amounts administered were 15.8 and 17.2 units/kg body weight in 30 and 20 min, respectively. The end infusion factor VII activity levels were 55 and 64%, respectively. Survival times of the exogenous components were 6.5 and 6 h, respectively. Satisfactory hemolstasis was obtained in both instances.
D000328:Adult; D001778:Blood Coagulation Disorders / Q000503:physiopathology* / Q000517:prevention & control; D005167:Factor VII / Q000502:physiology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D014081:Tooth Extraction
D005167:Factor VII