[Localization of embryonic aldolase isoenzyme in rat liver cells after a single injection of the carcinogen, 4-dimethylaminoazobenzene, and its noncarcinogenic analog].
The localization of a fetal isoenzyme of aldolase (A) in rat liver cells early after a single injection of carcinogen 4-dimethylaminoazobenzene and its noncarcinogenic analog 4-diethylaminoazobenzene has been studied using the immunofluorescent method. Aldolase A was found in the cytoplasm of oval and "transition" cells. These cells appeared in rat liver as a result of treatment with carcinogen and its analog. In mature hepatocytes aldolase A was not found either in intact rat liver, after the treatment with carcinogen or its analog.
D000818:Animals; D004622:Embryo, Mammalian / Q000201:enzymology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005634:Fructose-Bisphosphate Aldolase / Q000032:analysis*; D007114:Immunization; D007527:Isoenzymes / Q000032:analysis*; D008099:Liver / Q000201:enzymology*; D051381:Rats; D013997:Time Factors; D004124:p-Dimethylaminoazobenzene / Q000031:analogs & derivatives* / Q000494:pharmacology*
D007527:Isoenzymes; D004124:p-Dimethylaminoazobenzene; D005634:Fructose-Bisphosphate Aldolase
Lokalizatsiia émbrional'nogo izofermenta al'dolazy v kletkakh pecheni krys posle odnokratnoĭ in"ektsii kantserogena 4-dimetilaminoazobenzola i ego nekantserogennogo analoga.