[Karyotyping in chronic myeloproliferative syndrome (except chronic myeloid leukemia)].
Cytogenetics studies in chronic myeloproliferative disorders have brought evidence of acquired chromosomal abnormalities. Some markers are frequently seen: = 1 partial trisomy, with numerous varieties, = 7 monosomy, = 8 trisomy, = 9 trisomy, = 20 long arm deletion (20q-), and less often: iso 17q, Dq-, 6p-, 21q-. Cytogenetics studies performed during active therapy have shown various abnormalities, probably therapeutic-related. Prospectives studies are useful in order to estimate the frequency and significance of karyotype variation.
D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002900:Chromosomes, Human, 1-3; D002903:Chromosomes, Human, 19-20; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007621:Karyotyping; D009196:Myeloproliferative Disorders / Q000235:genetics*; D011379:Prognosis; D014314:Trisomy
Le caryotype dans les syndromes myéloprolifératifs chroniques (a l'exception de la leucémie myéloïde chronique).