[Hypophosphatemia after successful transplantation of the kidney. Clinico-experimental study].
The dynamic of indices changes of phosphorus treatment with nefrons in 16 patients after kidney transplantation was studied. The transitory hypophosphatemia accompanied with urine was typical in the majority of patients. The decrease of reabsorption and elevation of phosphorus clearance were noted. In a number of cases the phosphatemia level was increased due to reduction of prednisolone doses. It was experimentally revealed that prednisolone reduces the phosphorus absorption in intestine at 25% and the treatment by 1,25-dihydroxy-vitamin D3 and 1 alpha-hydroxyvitamin D3 promotes the normalization of this process.
D000293:Adolescent; D000328:Adult; D000818:Animals; D002112:Calcifediol / Q000627:therapeutic use; D002117:Calcitriol / Q000627:therapeutic use; D002118:Calcium / Q000097:blood; D002645:Chickens; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects; D016030:Kidney Transplantation; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008875:Middle Aged; D010710:Phosphates / Q000097:blood*; D011183:Postoperative Complications / Q000097:blood; D011239:Prednisolone / Q000627:therapeutic use
D010710:Phosphates; D011239:Prednisolone; D003404:Creatinine; D002117:Calcitriol; D002112:Calcifediol; D002118:Calcium
Hypophosphatämie nach erfolgter Transplantation der Niere. Klinisch-experimentelle Untersuchung.