Testing of Endosulfan and Fenitrothion for genotoxicity in Saccharomyces cerevisiae.
Two insecticides, Endosulfan and Fenitrothion, were tested for their ability to induce mitotic crossing-over, mitotic gene conversion and reverse mutation in Saccharomyces cerevisiae. Treatment of cells with Endosulfan increased the frequencies of gene convertants and revertants. However, Fenitrothion treatment did not induce any of these genetic events.
D002470:Cell Survival / Q000187:drug effects; D003434:Crossing Over, Genetic / Q000187:drug effects*; D004726:Endosulfan / Q000494:pharmacology*; D005278:Fenitrothion / Q000633:toxicity*; D008938:Mitosis / Q000187:drug effects; D009152:Mutagenicity Tests; D009153:Mutagens; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*
D009153:Mutagens; D004726:Endosulfan; D005278:Fenitrothion