Use of genetic markers in the colony management of nonhuman primates: a review.
Genetic markers in blood were used to identify paternity and reconstruct genealogical relationships in six captive breeding groups of rhesus monkeys (Macaca mulatta) using paternity exclusion analysis. The theoretical and observed incidence of inbreeding and its deleterious effects were discussed and colony management alternatives proposed for minimizing these effects. Genetic markers for disorders and both desirable and undesirable phenotypic characteristics have been sought so as to maximize the reproductive success and vitality of the colony by selective breeding. A sound genetic component such as that described here is a necessary adjunct to any successful long-term program for breeding nonhuman primates.
D000818:Animals; D000830:Animals, Laboratory / Q000235:genetics; D001947:Breeding; D005260:Female; D005804:Genes, Lethal; D005819:Genetic Markers; D005838:Genotype; D007178:Inbreeding; D008251:Macaca / Q000235:genetics*; D008253:Macaca mulatta / Q000235:genetics*; D008297:Male; D010334:Paternity; D010641:Phenotype; D011110:Polymorphism, Genetic
D005819:Genetic Markers