Analysis of the mixed association between human apolipoproteins A-I and A-II in aqueous solution.
The mixed association between two self-associating systems, human apolipoproteins A-I and A-II, has been evaluated by fluorescence spectroscopy and sedimentation equilibrium. The combined results are consistent with the formation of specific mixed oligomers between apolipoproteins A-I and A-II in aqueous solution. The data are discussed in terms of the role of protein-protein versus protein-lipid interactions in the quaternary organization of plasma lipoproteins.
D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins; D002942:Circular Dichroism; D006801:Humans; D008433:Mathematics; D011487:Protein Conformation; D013050:Spectrometry, Fluorescence; D014461:Ultracentrifugation; D014867:Water
D016632:Apolipoprotein A-I; D016633:Apolipoprotein A-II; D001053:Apolipoproteins; D014867:Water