Humoral immune function and experimental Escherichia coli infection in splenectomized dogs.
Intravenous administration of sheep red blood cells resulted in a deficient initial antibody response and provoked a much lower concentration of plaque forming cells in the blood of splenectomized dogs than in the control group. The in vitro serum opsonizing activity on Escherichia coli M-S-15 remained normal after splenectomy, and no difference was found between the test and the control group in the intravascular clearance rate of bacteria injected intravenously.
D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000276:immunology; D004285:Dogs; D004926:Escherichia coli / Q000276:immunology; D004927:Escherichia coli Infections / Q000276:immunology*; D006388:Hemagglutinins / Q000032:analysis; D006462:Hemolytic Plaque Technique; D007114:Immunization; D009895:Opsonin Proteins / Q000032:analysis; D010587:Phagocytosis; D013156:Splenectomy
D006388:Hemagglutinins; D009895:Opsonin Proteins