[Acute infections in pediatric surgery. Clinical experience with clindamycin (author's transl)].
76 children were treated with clindamycin at a dosage of 40 mg/kg/day for postsurgical wound infections, sepsis, phlegmon, peritonitis, osteomyelitis, pneumonia, mediastinitis, pyoderma and urinary tract infections. Frequency distribution of individual infectious agents: Staphylococci, 94,7%; Streptococci, 59,2%; Pneumococci, 5,3%; Enteroccocci, 25%; Escherichia coli, 10,5%; Pseudomonas, 14,5%; Proteus, 7,9%; Bacteroides, 6,6%; Clostridia, 7,9%. Therapy was successful in 83% of cases. Results were poor in 2 children treated for phlegmona, one case of mediastinitis and one of urinary tract infection, since organisms were predominantly gram-negative.
D000293:Adolescent; D001424:Bacterial Infections / Q000188:drug therapy*; D002481:Cellulitis / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000188:drug therapy; D010538:Peritonitis / Q000188:drug therapy; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013203:Staphylococcal Infections / Q000188:drug therapy; D013290:Streptococcal Infections / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy
D005839:Gentamicins; D002981:Clindamycin
Akute Infektionen in der Kinderchirurgie. Klinische Erfahrungen mit Clindamycin.