[The use of organic nitrates to lower intraocular pressure in outpatient and surgical treatment (author's transl)].
Intravenously administered nitroglycerin lowers intraocular pressure both in glaucoma patients and healthy subjects. The effect is dose-related. The use of the drug in ocular hypotensive therapy before and after surgery is suggested. Nitrates administered orally (isosorbide dinitrate 2 x 40 mg daily, depot form) bring about a comparable lowering of IOP and are suitable for outpatient treatment.
D004305:Dose-Response Relationship, Drug; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D005996:Nitroglycerin / Q000009:adverse effects / Q000627:therapeutic use*; D011300:Preoperative Care
D005996:Nitroglycerin; D007548:Isosorbide Dinitrate
Untersuchungen zur ambulanten und perioperativen Augeninnendrucksenkung mit organischen Nitraten.