Reduction of epoxy derivatives of benzo(a)pyrene by microsomal cytochrome P-450.
D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; D000818:Animals; D001580:Benzopyrenes / Q000037:antagonists & inhibitors / Q000378:metabolism*; D001711:Biotransformation / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000037:antagonists & inhibitors / Q000378:metabolism; D010100:Oxygen / Q000494:pharmacology; D051381:Rats; D012256:Riboflavin / Q000378:metabolism
D001580:Benzopyrenes; C023393:benzo(a)pyrene 7,8-oxide; C006707:benzo(a)pyrene 4,5-epoxide; D015123:7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; C019772:benzopyrene 4,5-oxide reductase; D010100:Oxygen; D012256:Riboflavin