[Functional diagnostics of the adrenal cortex following long term treatment with prednisolone].
Promounced cases of disturbances of the function of the adrenal cortex may more certainly be found out with the help of the enlarged sinacthen test than after a stimulation done only but once. In a long-term prednisolone therapy of 10 mg/a day we could observe signs of disturbances of the function of the adrenal cortex. A clear evidence in the estimation of the individual value is possible only in decreased plasmacortisol levels which are during the whole course of the experiment. When a prednisolone therapy is established for a longer time apart from the sequels at the adrenal cortex should be thought also of the great number of the side effects caused by the catabolic properties of the cortico-steroids.
D015062:11-Hydroxycorticosteroids / Q000652:urine; D000302:Adrenal Cortex / Q000503:physiopathology*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000503:physiopathology*; D004809:Ephedrine; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D008134:Long-Term Care; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D011239:Prednisolone / Q000008:administration & dosage*
D015062:11-Hydroxycorticosteroids; D011239:Prednisolone; D004809:Ephedrine; D006854:Hydrocortisone
Zur Funktionsdiagnostik der Nebennierenrinde nach Prednisolonlangzeittherapie.