[Translocations t(2;8) and t(8;22) in continuous cell lines of African Burkitt's lymphoma].
Chromosome studies were performed by EBV positive African Burkitt lymphoma cell lines. Variant translocations were found in 4 cases: two with t(2;8) (p12;q23 ou 24) and two with t(8;22) (q23 or 24;q11). Identical translocations were observed in EBV positive or negative non-african lymphomas or Burkitt type leukemia. These results show the uniqueness of Burkitt lymphoma leukemia and stress the importance of chromosome 8 rearrangement in this tumor.
D000354:Africa, Western; D002051:Burkitt Lymphoma / Q000235:genetics* / Q000473:pathology; D002460:Cell Line; D002900:Chromosomes, Human, 1-3; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D014178:Translocation, Genetic
Translocations t(2;8) et t(8;22) dans des lignées cellulaires continues de lymphomes de Burkitt africain.