Inhibition of uridinediphosphate glucuronyltransferase caused by furosemide.
The diuretic agent, furosemide, inhibits liver microsomal uridinediphosphate glucuronyltransferase (EC. 2.4.1.17), in monkey and rat. Inhibition is of the non-competitive type.
D000818:Animals; D005665:Furosemide / Q000494:pharmacology*; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors*; D006168:Guinea Pigs; D000882:Haplorhini; D007700:Kinetics; D008253:Macaca mulatta; D008862:Microsomes, Liver / Q000201:enzymology*; D051381:Rats; D013045:Species Specificity
D005665:Furosemide; D014453:Glucuronosyltransferase