Muscarinic cholinergic agonists at picomolar to nanomolar concentrations produce contractions of isolated rat aortae.
D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects; D001285:Atropine / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D016210:Methacholine Chloride; D008688:Methacholine Compounds / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011950:Receptors, Cholinergic / Q000187:drug effects*; D011976:Receptors, Muscarinic / Q000187:drug effects*
D008688:Methacholine Compounds; D011950:Receptors, Cholinergic; D011976:Receptors, Muscarinic; D016210:Methacholine Chloride; D001285:Atropine; D009638:Norepinephrine