Ironstrene (ferric sodium edetate) treatment of anaemic infants.
This study deals with haemoglobin (Hb) measurements of healthy 1-year-old children in one district in central Norway. The aim was to study the Hb levels, to treat any children having iron deficiency anaemia (Hb less than or equal to 10.8 g/100 ml), and to evaluate the effect of sodium iron edetate after 4 weeks of treatment, with a follow-up after 1 year. A total of 141 children were examined, of whom 40 had Hb less than or equal to 10.8 g/100 ml (28.4%). The study showed that the Hb levels in healthy 1-year-olds have a normal distribution. Thirty-four children with Hb less than or equal to 10.8 g/100 ml were treated for 4 weeks with sodium iron edetate (six drop-outs). The study showed a significant increase in Hb levels immediately after the treatment period as well as 4 weeks later. Hb decreases significantly immediately after ceasing treatment and continues to do so during the control period of 1 year. The Hb levels probably increase to a maximum 2 weeks after the treatment period.
D000747:Anemia, Hypochromic / Q000188:drug therapy*; D004492:Edetic Acid / Q000627:therapeutic use*; D005260:Female; D005290:Ferric Compounds / Q000627:therapeutic use; D006454:Hemoglobins; D006801:Humans; D007223:Infant; D007502:Iron Chelating Agents / Q000627:therapeutic use*; D008297:Male
D005290:Ferric Compounds; D006454:Hemoglobins; D007502:Iron Chelating Agents; D004492:Edetic Acid; C019179:Fe(III)-EDTA