[Ethanol kinetics in the blood of rats at the stage of physical ethanol dependence as well as in the period of its withdrawal].
Gas liquid chromatography was used to study the kinetics of ethanol in the blood of rats during alcohol dependence and withdrawal. Chronic alcoholization was shown to lead to a considerable increase in the activity of the ethanol-oxidizing enzymatic systems. These systems were revealed to be hyperactive during alcohol withdrawal after 8-month consumption. It is concluded that hyperactivity of the ethanol-oxidizing systems during alcohol withdrawal may play an important role in the formation of alcohol abstinence symptoms.
D000429:Alcohol Oxidoreductases / Q000097:blood; D000437:Alcoholism / Q000097:blood*; D000818:Animals; D002849:Chromatography, Gas; D000431:Ethanol / Q000097:blood*; D006801:Humans; D007700:Kinetics; D008297:Male; D051381:Rats; D013375:Substance Withdrawal Syndrome / Q000097:blood*
D000431:Ethanol; D000429:Alcohol Oxidoreductases
Izuchenie kinetiki étanola v korvi krys na stadii fizicheskoĭ zavisimosti ot étanola, a takzhe v period ego lisheniia.