[Electrocorticograms and the histochemical effects in the rat accompanying the reactivation of cholinesterases after the effects of an organophosphorus inhibitor].
The administration of paraoxon, an organophosphate inhibitor of cholinesterases, elicits theta rhythms, fast rhythms and paroxystical alterations on the electrocorticogram of the Rat. The disappearance of these abnormalities of the cortical activity after administration of aromatic oximes seems to be in good correlation with the restoration of cerebral cholinesterase activity revealed by histochemical method.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001921:Brain / Q000201:enzymology; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology*; D002802:Cholinesterases / Q000378:metabolism*; D004569:Electroencephalography; D005260:Female; D008297:Male; D010091:Oximes / Q000494:pharmacology*; D010261:Paraoxon / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D051381:Rats
D010091:Oximes; D001285:Atropine; D002802:Cholinesterases; D010261:Paraoxon
Electrocorticogrammes et effets histochimiques accompagnant chez le rat la réactivation des cholinestérases après action d'un inhibiteur organophosphoré.