Morphine injections into the periaqueductal-periventricular gray attenuate septal hyperreactivity.
Animals with septal lesion-induced reactivity were injected with 2 dose levels of morphine in the periaqueductal-periventricular gray. Both doses of morphine transiently attenuated the reactivity. Naloxone injected IP significantly antagonized the morphine attenuation of the septal-lesion induced reactivity.
D000818:Animals; D001921:Brain / Q000187:drug effects*; D007267:Injections; D008297:Male; D009020:Morphine / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects*; D009270:Naloxone / Q000494:pharmacology; D051381:Rats
D009270:Naloxone; D009020:Morphine