Chromosomes XIV and XVII of Saccharomyces cerevisiae constitute a single linkage group.
We present several lines of evidence that chromosomes XIV and XVII of Saccharomyces cerevisiae are not independent chromosomes, but rather constitute a single linkage group. Studies which made use of a new mapping method based on the haploidization-without-recombination meiotic phenotype of the spoll mutant initially indicated that markers on chromosomes XIV and XVII were linked. Tetrad analysis was used to establish gene-gene distances, and a new chromosome XIV map incorporating markers originally assigned to chromosome XVII was derived. During the course of trisomic segregation studies, we discovered that a 2n + 2 homothallic diploid, originally believed to be tetrasomic for chromosome XVII (now XIV), carries two normal chromosome XIV homologs and two aberrant homologs which appear to be deficient for a large portion of the right arm of XIV. The previous evidence that established chromosome XVII as an independent linkage group is discussed in the light of these findings.
D002874:Chromosome Mapping; D002875:Chromosomes; D008040:Genetic Linkage; D005819:Genetic Markers; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000648:ultrastructure; D013172:Spores, Fungal / Q000235:genetics
D005819:Genetic Markers