[Histomorphometry of the vascularization of the placental villi in diabetic pregnant women].
The pathomorphological findings in the placentae of diabetic pregnant women were studied in 12 cases of maternal diabetes. The vascularization quotient of the placental villi (VQ) is defined as the surface area of the cut across the villus divided by the surface area of the capillaries within the villus. The vascularization quotient of the diabetic mothers was compared with control placentas of healthy maternity patients. It was found that in normal placentas about half of the surface of the villus is taken up by the surface of capillaries (VQ = 0.44). In diabetics about 1/4 of the villus surface is taken up by capillary surface (VQ = 0.23). The villi of diabetic placentas showed in general fewer capillaries in larger villi. These changes were more marked if normo-glycaemia was obtained late in pregnancy by the administration of insulin. The findings were in no correlation to Whites classification of the pregnancy which measures factors which are independent of pregnancy.
D002196:Capillaries / Q000473:pathology; D002824:Chorionic Villi / Q000098:blood supply*; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D010920:Placenta / Q000098:blood supply* / Q000473:pathology*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000188:drug therapy / Q000473:pathology*; D013997:Time Factors
D007328:Insulin
Zur Histomorphometrie der Zottenvaskularisation von Plazenten diabetischer Mütter.