Phenylalanine lowers melanin synthesis in mammalian melanocytes by reducing tyrosine uptake: implications for pigment reduction in phenylketonuria.
D000818:Animals; D006224:Cricetinae; D006801:Humans; D008543:Melanins / Q000096:biosynthesis*; D008544:Melanocytes / Q000187:drug effects* / Q000201:enzymology; D008545:Melanoma / Q000378:metabolism; D014442:Monophenol Monooxygenase / Q000032:analysis; D009374:Neoplasms, Experimental; D010649:Phenylalanine / Q000494:pharmacology*; D010661:Phenylketonurias / Q000378:metabolism*; D012878:Skin Neoplasms / Q000378:metabolism; D012880:Skin Pigmentation / Q000187:drug effects; D014443:Tyrosine / Q000378:metabolism
D008543:Melanins; D014443:Tyrosine; D010649:Phenylalanine; D014442:Monophenol Monooxygenase