[Genetic activity of 1,2-dichloroethylene. A). In vitro studies].
1,2-dichloroethylene cis and trans were tested for their ability to induce point mutation, mitotic gene conversion and mitotic recombination in a diploid strain (D7) of the yeast Saccharomyces cerevisiae in a suspension test with and without a mammalian microsomal activation system. In this test 1,2-DCE cis and trans were toxic but not genetically active even with S9 activation.
D004000:Dichloroethylenes / Q000633:toxicity*; D006843:Hydrocarbons, Chlorinated / Q000633:toxicity*; D007536:Isomerism; D008938:Mitosis / Q000187:drug effects*; D009152:Mutagenicity Tests; D012441:Saccharomyces cerevisiae / Q000187:drug effects
D004000:Dichloroethylenes; D006843:Hydrocarbons, Chlorinated; C035384:1,2-dichloroethylene
Attivita' genetica dell'1,2-dicloroetilene. A) Studio in vitro.