Neuroendocrinological aspects of histiocytosis X of the central nervous system.
Detailed neuroendocrine studies were carried out in a patient with histiocytosis X involving the hypothalamus. She presented with amenorrhea, galactorrhea, and diabetes insipidus. The diagnosis was established through needle biopsy with the aid of a computerized tomography (CT) scanner. The basic pathology and clinical features of the disease are outlined, with particular emphasis on the endocrine abnormalities seen in isolated hypothalamic histiocytosis X.
D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000378:metabolism*; D006801:Humans; D007027:Hypothalamic Diseases / Q000000981:diagnostic imaging / Q000378:metabolism*; D007980:Levodopa / Q000494:pharmacology; D011388:Prolactin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D014057:Tomography, X-Ray Computed
D007980:Levodopa; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013006:Growth Hormone