[Clinical experiences with diazepam (Valium) - fentanyl combination anesthesia in neurosurgery. A study of circulation and oxygen consumption].
This clinical study was performed on 13 neurosurgical patients. The mean age was 56 years (range 45-70 years). After induction of anesthesia the heart rate diminished by 21.4%, the mean pressure by 12.2% in the same time decreased the cardiac output by 19.3%, the calculated total peripheral resistance increased by 13%. The oxygen uptake decreased by 16%. The advantages and contraindications of this technique in neuroanesthesia are discussed.
D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000097:blood; D002302:Cardiac Output / Q000187:drug effects; D003975:Diazepam / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D010101:Oxygen Consumption / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects
D002245:Carbon Dioxide; D003975:Diazepam; D005283:Fentanyl
Klinische Erfahrungen mit der Diazepam-(Valium)-Fentanyl-Kombinationsnarkose in der Neurochirurgie. Untersuchungen des Kreislaufs und des Sauerstoffverbrauchs.