[Lipid transformation into glycogen in animal and human cells].
On the basis of analysis of the literature and the author's data a hypothesis of transformation of lipids into glycogen in animal and human cells by means of microbodies and lysosomes as one of the universal adaptative reactions of the host is substantiated. In the opinion of the author, both microbodies and lysosomes may take part both in the process of oxidation of intracellular lipids up to intermediate metabolism products and in the process of glycogen synthesis from these products. As a result of enhanced oxidation and transformation of lipids into glycogen the energy of the cell improves and the possibility of development of fatty dystrophy decreases. The hypothesis is based on the structural association of microbodies, lysosomes, fatty and glycogen inclusions observed by the author in cells of various organs in different pathological processes, as well as on certain biochemical data.
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001711:Biotransformation; D003920:Diabetes Mellitus / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism; D004285:Dogs; D005215:Fasting; D005943:Gluconeogenesis; D006003:Glycogen / Q000096:biosynthesis*; D006651:Histocytochemistry; D006801:Humans; D050356:Lipid Metabolism; D008112:Liver Glycogen / Q000096:biosynthesis; D008247:Lysosomes / Q000378:metabolism; D008830:Microbodies / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D012867:Skin / Q000378:metabolism
D008112:Liver Glycogen; D006003:Glycogen
Transformatsiia lipidov v glikogen v kletkakh zhivotnykh i cheloveka.