Inactivation of vascular prostacyclin synthetase by platelet lipoxygenase products.
D001011:Aorta / Q000201:enzymology; D001095:Arachidonic Acids / Q000494:pharmacology; D001792:Blood Platelets / Q000201:enzymology*; D001808:Blood Vessels / Q000201:enzymology*; D003577:Cytochrome P-450 Enzyme System; D011464:Epoprostenol / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D006801:Humans; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology; D019746:Intramolecular Oxidoreductases; D008084:Lipoxygenase / Q000097:blood*; D008861:Microsomes / Q000201:enzymology; D011453:Prostaglandins / Q000096:biosynthesis*; D011463:Prostaglandins H / Q000378:metabolism
D001095:Arachidonic Acids; D011453:Prostaglandins; D011463:Prostaglandins H; D003577:Cytochrome P-450 Enzyme System; D011464:Epoprostenol; D008084:Lipoxygenase; D019746:Intramolecular Oxidoreductases; C022461:prostacyclin synthetase; D007213:Indomethacin