Anticentromere antibody and primary pulmonary hypertension.
A patient is described with pulmonary hypertension complicating rheumatoid arthritis. Anticentromere antibody, a test of high specificity for the CREST syndrome, was present in the serum. Confirmation of this observation may lead to an improved classification of "primary" pulmonary hypertension.
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D002503:Centromere / Q000276:immunology*; D002875:Chromosomes / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006657:Histones / Q000276:immunology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000276:immunology*; D011928:Raynaud Disease / Q000276:immunology; D012217:Rheumatoid Factor / Q000032:analysis; D012595:Scleroderma, Systemic / Q000276:immunology; D014657:Vasculitis / Q000276:immunology
D000974:Antibodies, Antinuclear; D006657:Histones; D012217:Rheumatoid Factor