[Ultrastructural changes in the lungs in experimental M. pneumoniae infection].
The ultrastructural changes in the lungs were studied in aerosol infecting of Syrian hamsters with M.pneumoniae culture (10(8)--10(9) CFU, at a rate of 0.1 ml per animal). It was found that the pathological process began with an intensive vascular reaction followed by a very speedy interstitial and serous-desquamative pneumonia with hemorrhagic component. Mycoplasmae in the lungs were seen in the lumen of the vessels being in close contact with red cells and leukocytes, which points to a possibility of hematogenic dissemination. Phagocytosis of mycoplasmae by macrophages and endothelial cells was found. Mycoplasmae changed their ultrastructure in the course of interaction with the macroorganism.
D000818:Animals; D006224:Cricetinae; D005260:Female; D008168:Lung / Q000648:ultrastructure*; D008647:Mesocricetus; D008854:Microscopy, Electron; D009177:Mycoplasma pneumoniae / Q000648:ultrastructure; D011019:Pneumonia, Mycoplasma / Q000473:pathology*
Ul'trastrukturnye izmeneniia v legkikh pri infektsii M. pneumoniae v éksperimente.