Blood groups in animals.
The membrane of RBC is literally peppered with a great variety of antigenic determinants (blood factors). Some are fixed genetically, ie, they occur on the RBC of all members of the species under study. Others segregate genetically, ie, they occur on the RBC of some but not all members of the species under study. It is these segregrating determinants that form the blood groups proper, the classic example being blood factors A and B of the ABO system of human blood groups. The number of blood group determinants varies considerably between species (eg, greater than 80 in domestic cattle to only 1 in the new world Camelidae). Genetic analysis has shown that the blood factors belong to one or another of a limited number of blood group systems. Some of these systems, similar to the B system of cattle, are enormously complex, whereas others involve but a single blood factor. The object of the present paper is to report on the extent of genetic variation in blood groups and how information on blood groups is being used clinically.
D000818:Animals; D000829:Animals, Domestic / Q000097:blood*; D001188:Artiodactyla; D001789:Blood Group Antigens / Q000235:genetics; D001788:Blood Grouping and Crossmatching / Q000662:veterinary; D001803:Blood Transfusion / Q000662:veterinary; D001947:Breeding; D002415:Cats; D002417:Cattle; D002645:Chickens; D003429:Cross Reactions; D004285:Dogs; D005260:Female; D005611:Freemartinism / Q000175:diagnosis; D006736:Horses; D008297:Male; D011247:Pregnancy; D011817:Rabbits; D012756:Sheep; D013552:Swine; D065227:Transfusion Reaction
D001789:Blood Group Antigens