[Oxygen transport function of the blood in acute disorders of gas metabolism and of the acid-base state].
The oxygen-transport function of blood in hyperoxia and acute disturbances of the acid-alkali condition was studied in "oxygenator--desoxygenator" as a model. It has been established that in acidosis there occurs decreased intensity of glycolysis in erythrocytes, accumulation of 2,3 diphosphoglyceric acid which decreases affinity of hemoglobin for oxygen. It does not occur in alcalosis.
D000137:Acid-Base Imbalance / Q000097:blood*; D000142:Acidosis, Respiratory / Q000097:blood*; D000208:Acute Disease; D000472:Alkalosis, Respiratory / Q000097:blood*; D001692:Biological Transport; D002245:Carbon Dioxide / Q000097:blood; D004734:Energy Metabolism; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D008961:Models, Structural; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000378:metabolism
D010108:Oxyhemoglobins; D002245:Carbon Dioxide; D010100:Oxygen
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