Cell cycle variability: the oscillator model of the cell cycle yields transition probability alpha and beta type curves.
The limit cycle concept of cell replication attributes cell cycle variability to continuous random modulation of the rates of reactions forming the intracellular control system believed to be responsible for replication processes. It is shown that this model can yield frequency histograms and both alpha and beta type accumulative distribution curves (with respect to generation times and also to cycle phases) which are of the various forms seen experimentally. The results thus provide additional support for this concept.
D002453:Cell Cycle; D002455:Cell Division; D008954:Models, Biological; D011336:Probability; D013997:Time Factors