4-[(Aminoalkyl)amino]-1,2-dimethoxynaphthalenes as antimalarial agents.
A series of 4-[N-(aminoalkyl)amino]-1,2-dimethoxynaphthalenes was prepared and tested for radical curative activity in rhesus monkeys infected with P. cynomolgi. Some radical curative activity was observed.
D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D000882:Haplorhini; D008253:Macaca mulatta; D008288:Malaria / Q000188:drug therapy; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000494:pharmacology; D010961:Plasmodium / Q000187:drug effects
D000962:Antimalarials; D009281:Naphthalenes