Solid phase radioimmunoassays (SPRIA) using antibodies covalently bound to controlled pore glass (CPG).
Covalent coupling of antibody molecules has found broad application in the area of radioimmunoassay (RIA). A complete set of convenient thyroid assays has been developed employing both conventional and some new RIA techniques. These assays offer the clinician rapid and precise data quickly so that appropriate diagnosis can be speedily accomplished. Some of the techniques presented could only have been done with this technology. Details of assays for T4, T3, TBG, TSH, and FT4 are presented in this paper.
D000906:Antibodies / Q000276:immunology; D005898:Glass; D006801:Humans; D011863:Radioimmunoassay / Q000379:methods*; D012712:Serum Globulins / Q000032:analysis; D013963:Thyroid Hormones / Q000097:blood* / Q000276:immunology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000032:analysis
D000906:Antibodies; D012712:Serum Globulins; D013963:Thyroid Hormones; D013975:Thyroxine-Binding Proteins; D013972:Thyrotropin; D013974:Thyroxine