[Effect of dynamic factors of space flight on the mutagenic effect of radiation. I. Occurrence of dominant lethal mutations during Drosophila melanogaster oogenesis].
The modifying effect of dynamic space flight factors (DF) on radiation chromosomal damages in Drosophila oocytes of the 7-th and 14-th stages was studied. It has been found that the number of dominant lethal mutations increases under the simultaneous action of radiation and dynamic factors on oocytes-7. The magnitude of radiation effect on mature oocytes did not change upon additional action of DF. It is assumed that the modifying effect of DF on radiation damage may be a reason for discrepancy of flight experimental results.
D000818:Animals; D004331:Drosophila melanogaster; D005260:Female; D005720:Gamma Rays; D005799:Genes, Dominant / Q000528:radiation effects*; D005804:Genes, Lethal / Q000528:radiation effects*; D009154:Mutation / Q000528:radiation effects*; D009865:Oocytes / Q000528:radiation effects*; D010063:Ovum / Q000528:radiation effects*; D013026:Space Flight
Vliianie dinamicheskikh faktorov kosmicheskogo poleta na mutagennyĭ éffekt radiatsii. Soobshchenie I. Vozniknovenie dominantnykh letal'nykh mutatsiĭ v oogeneze Drosophila melanogaster.