Folate analogues altered in the C9--N10 bridge region. 14. 11-Oxahomofolic acid, a potential antitumor agent.
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D004352:Drug Resistance, Microbial; D005492:Folic Acid / Q000031:analogs & derivatives*; D005493:Folic Acid Antagonists; D007780:Lacticaseibacillus casei / Q000187:drug effects / Q000201:enzymology; D008727:Methotrexate / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism
D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists; C100117:homofolic acid; C023461:11-oxahomofolic acid; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D008727:Methotrexate