Alteration of polypeptide backbone structure as determined by circular dichroic spectral analysis in relation to change of plasminogen activator activity of two forms of human urinary urokinase denatured with guanidine hydrochloride.
D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D010450:Endopeptidases / Q000652:urine*; D019791:Guanidine; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D010446:Peptide Fragments; D010960:Plasminogen Activators / Q000652:urine*; D011489:Protein Denaturation; D014568:Urokinase-Type Plasminogen Activator / Q000652:urine*
D006146:Guanidines; D010446:Peptide Fragments; D010450:Endopeptidases; D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator; D019791:Guanidine