[Fine morphology of the anomalies of sporulation in Clostridium tetani].
The electron microscopic study of the cultures of Cl. tetani strains Nos. 154 and 741 has been carried out, starting from the late stationary phase of their development in a liquid culture medium prepared on the basis of casein hydrolysate. Under experimental conditions sporogenesis is observed in 17-33% of the organisms in the population of strain No. 154 and in 7-14% of the organisms in the population of strain No. 471. In most of the sporulating cells sporogenesis occurs in consecutive stages commonly observed in clostridia. Anomalies in the formation of pores are manifested by the ectopic initial formation of protospores, the disordered excess growth of osmiophil structures of the exosporic type, the early lysis of the cytoplasmic structures of the sporangium cell or the spore itself. Such changes resulting in the death of the cell are regarded as the pathomorphology of the bacterial cell.
D001433:Bacteriolysis; D003017:Clostridium tetani / Q000502:physiology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009024:Morphogenesis; D013171:Spores, Bacterial / Q000502:physiology / Q000648:ultrastructure
Tonkaia morfologiia anomaliĭ formirovaniia spor u Clostridium tetani.