[Problems of immunoglobulin analysis in IgD-plasmacytoma].
We succeeded in proving the specific monoclonal immune globulin in a case of IgD-plasmocytoma only relatively late after generalisation of the disease. The immunoelectrophoretic findings changed under the antineoplastic system therapy in such a way that the specific line of immune globulins was demonstrated much weakened and a new strong precipitation line for free easy chains of type L appeared. When the findings were not carefully inspected without doubt an easy chain plasmocytoma might have been diagnosed. The findings can earliest be explained by a further increase of the spontaneous readiness for decay which already exists in the immune globulin D under the cytostatic therapy.
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007072:Immunoglobulin D / Q000032:analysis*; D007137:Immunoglobulin alpha-Chains / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use
D007072:Immunoglobulin D; D007137:Immunoglobulin alpha-Chains; D007146:Immunoglobulin lambda-Chains; D003520:Cyclophosphamide; D011241:Prednisone
Zur Problematik der Immunglobulinanalyse beim IgD-Plasmozytom.