Experience of three-day trimethoprim therapy for dysuria-frequency in primary health care.
Dysuria-frequency in 78 patients was treated for 3 consecutive days with 300 mg trimethoprim administered in a single dose at night. Symptomatic cure was noted in 90% of the patients one week after initiation of therapy. In this investigation a positive urinary culture was found in 74% of the patients and bacteriological cure was obtained in all patients but one. A new infection was registered in 2 patients when controlled one week after the start of therapy. The isolated microorganisms were Escherichia coli in 52% of the cases and Staphylococcus saprophyticus in 29%. The high frequency of the latter offers an explanation to the low reliability of the nitrite dip test in diagnosing significant bacteriuria in this study.
D000293:Adolescent; D000328:Adult; D004334:Drug Administration Schedule; D004927:Escherichia coli Infections / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy; D014295:Trimethoprim / Q000008:administration & dosage*; D014552:Urinary Tract Infections / Q000188:drug therapy*; D014555:Urination Disorders / Q000188:drug therapy*
D014295:Trimethoprim