Immunopathology of the amyloid diseases.
The relentless accumulation of nonimmunogenic fibrils that resist phagocytosis, proteolysis, and other normal host defense mechanisms leads to death when amyloidosis involves vital organs. Effective treatment for most of the amyloidoses lies in the future, but recent findings have enabled a classification of these diseases and are beginning to shed some light on possible pathogenetic mechanisms.
D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis; D008970:Molecular Weight
D000682:Amyloid; D007147:Immunoglobulin Light Chains