[The toxicological evaluation of styrene as an industrial chemical].
Recent development in toxicological study of styrene is summarized from the viewpoint of occupational health. The topics discussed are: 1) physico-chemical properties, 2) industrial use, work place environments and exposure control, 3) metabolism and biological monitoring of exposure, 4) general toxicity with special reference to dose-effect/response relationship in humans, and 5) in vitro and in vivo mutagenicity, mammalian teratogenicity and human/subhuman carcinogenicity. With 137 references.
D000014:Abnormalities, Drug-Induced; D000328:Adult; D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004781:Environmental Exposure; D005260:Female; D005333:Fetus / Q000187:drug effects; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D008991:Monitoring, Physiologic; D009153:Mutagens; D009369:Neoplasms / Q000139:chemically induced; D009422:Nervous System Diseases / Q000139:chemically induced; D009787:Occupational Medicine; D011247:Pregnancy; D011270:Pregnancy, Animal; D011817:Rabbits; D051381:Rats; D013343:Styrenes / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*
D009153:Mutagens; D013343:Styrenes