Computer simulation of metal ion equilibria in biofluids. Part 3. Trace metal supplementation in total parenteral nutrition.
Computer simulation models have been developed to investigate the effect of intravenous infusions of nutritive amino acid solutions metal equilibria in plasma. The distribution of Ca(II), Mg(II), Zn(II), Cu(II), and Mn(II) among the ligands in the nutritive fluid is calculated and used to estimate the amounts of each metal that should be included in future preparations.
D000596:Amino Acids / Q000097:blood*; D002118:Calcium / Q000097:blood; D003201:Computers; D003300:Copper / Q000032:analysis; D006801:Humans; D008274:Magnesium / Q000097:blood; D008345:Manganese / Q000097:blood; D008954:Models, Biological; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total; D014131:Trace Elements / Q000097:blood*; D015032:Zinc / Q000097:blood
D000596:Amino Acids; D014131:Trace Elements; D008345:Manganese; D003300:Copper; D008274:Magnesium; D015032:Zinc; D002118:Calcium