[Comparative study of various routes of vaccination and testing. An instance of a killed bacterial vaccine].
The efficiency of intranasal subcutaneous, aerosol and digestive vaccinations with killed Klebsiella pneumoniae as vaccine was studied on the survival curves after experimental disease with pathogen K. pneumoniae I inoculated by the same routes. Results show that the local immunization is an important factor of protection and the intranasal route is very convenient.
D000281:Administration, Intranasal; D000284:Administration, Oral; D000336:Aerosols; D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D004353:Drug Evaluation, Preclinical; D007279:Injections, Subcutaneous; D007711:Klebsiella pneumoniae / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C
D000336:Aerosols; D001428:Bacterial Vaccines
Etude comparée de différentes voies de vaccination et d'épreuve. Cas d'un vaccin bactérien tué.