Effects of gestation on glucose tolerance and plasma insulin in cynomolgus monkeys (Macaca fascicularis).
Gestational alterations in carbohydrate metabolism in a group of cynomolgus monkeys were characterized by a decrease in fasting plasma glucose and by an increase in peak plasma insulin response subsequent to a glucose challenge. These changes are prominent as early as the first trimester of pregnancy. Glucose clearance rates and fasting plasma insulin did not show significant changes during gestation or post partum. Peak plasma insulin remained elevated in lactating animals studied 4 to 10 weeks post partum.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D005951:Glucose Tolerance Test; D007328:Insulin / Q000097:blood*; D008252:Macaca fascicularis; D011247:Pregnancy
D001786:Blood Glucose; D007328:Insulin