Activity of carbonic anhydrase in stored blood.
The activity of carbonic anhydrase in blood stored in CPD at 4 degrees C for up to 31 days was measured electrometrically at 5-day intervals and compared with that in fresh blood taken from four normal subjects. No change in activity in stored red cell lysates was observed over this period. There was a clear increase in activity in serum from stored blood with time. These results are discussed in the context of alveolar-to-arterial carbon dioxide gradients seen occasionally in patients following massive transfusions of stored blood.
D001793:Blood Preservation; D002256:Carbonic Anhydrases / Q000097:blood*; D004909:Erythrocyte Indices; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013997:Time Factors
D006454:Hemoglobins; D002256:Carbonic Anhydrases