Interactions of propranolol with some analgesics.
The duration of the analgesic effect of levomepromazine was prolonged in mice when associated with propranolol. The administration of morphine to animals treated with propranolol resulted in an increase of morphine toxicity with death of some animals.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D005260:Female; D008297:Male; D008728:Methotrimeprazine / Q000494:pharmacology*; D051379:Mice; D009020:Morphine / Q000494:pharmacology* / Q000633:toxicity; D011433:Propranolol / Q000494:pharmacology*; D013997:Time Factors
D009020:Morphine; D008728:Methotrimeprazine; D011433:Propranolol