An estimate of the global error frequency in translation.
Electrophoretic heterogeneity in a set of selected proteins is used to estimate the average error frequency during translation. Estimates based upon streptomycin-induced heterogeneity as well as mistranslation of an ochre codon yield an average error frequency of 4 x 10(-4) for normally growing cells.
D004926:Escherichia coli / Q000235:genetics*; D007526:Isoelectric Point; D008970:Molecular Weight; D009154:Mutation; D014176:Protein Biosynthesis / Q000187:drug effects; D012269:Ribosomal Proteins / Q000235:genetics; D012270:Ribosomes / Q000378:metabolism; D013307:Streptomycin / Q000494:pharmacology
D012269:Ribosomal Proteins; D013307:Streptomycin