Antibiotic sensitivities of gonococci isolated in Rotterdam and results of treatment with cefuroxime.
In a study of the efficacy of cefuroxime in the treatment of 278 cases of acute gonorrhoea (including rectal and pharyngeal infections and infections due to penicillinase-producing Neisseria gonorrhoeae), high cure rates were found for both male (98.8%) and female patients (98.6%). Disadvantages of this treatment are its high cost and the relatively high proportion of patients who develop postgonococcal urethritis.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002444:Cefuroxime / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000201:enzymology; D009426:Netherlands; D010405:Penicillinase / Q000096:biosynthesis
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010405:Penicillinase; D002444:Cefuroxime