[Mitotic activity changes in serous ovarian cystadenocarcinomas under treated with chemotherapy].
The intraoperative material was examined morphologically in 254 patients, aged from 31 to 71, with serous ovarian cystadenocarcinoma. One hundred patients were not given a preoperative course of chemotherapy, and 154 patients were administered thio-TEPA in various dosage. As a dose of the drug was increased less mitotic activity was noted, which may serve as a quantitative indicator of the chemotherapy efficacy.
D000328:Adult; D000368:Aged; D003537:Cystadenoma / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D008938:Mitosis / Q000187:drug effects*; D009852:Omentum; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010534:Peritoneal Neoplasms / Q000556:secondary; D011300:Preoperative Care; D013852:Thiotepa / Q000627:therapeutic use
D013852:Thiotepa
Izmeneniia mitoticheskoĭ aktivnosti v seroznykh tsistadenokartsinomakh iaichnika pod vliianiem khimioterapii.