Disseminated toxoplasmosis. Case report and review of the literature.
A 40-year-old man had disseminated toxoplasmosis preceded by miliary tuberculosis and associated with skin anergy. In previously reported cases of disseminated toxoplasmosis, the three organs most commonly involved were brain, heart, and  lungs. The histopathologic picture of toxoplasmal lymphadenopathy was not present in our case or in previously reported cases. Therefore, we believe that the diagnosis of disseminated toxoplasmosis should not be rejected simply because of the likely absence of toxoplasmal lymphadenopathy in biopsy material. The thymus in our case was morphologically abnormal and showed features suggestive of an autoimmune process.
D000328:Adult; D001344:Autopsy; D002525:Cerebellar Cortex / Q000469:parasitology / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006801:Humans; D008168:Lung / Q000469:parasitology / Q000473:pathology; D008198:Lymph Nodes / Q000469:parasitology / Q000473:pathology; D008297:Male; D009336:Necrosis; D010179:Pancreas / Q000469:parasitology; D012698:Serologic Tests; D013950:Thymus Gland / Q000473:pathology / Q000648:ultrastructure; D014122:Toxoplasma / Q000276:immunology / Q000648:ultrastructure; D014123:Toxoplasmosis / Q000469:parasitology / Q000473:pathology*