[Tranquilizing effect of n-dipropylacetate and other GABA-ergic substances in conflict situations].
Effect of n-dipropyl acetate (n-DPA), amino oxyacetic acid (AOAA), pantogam and piracetam on rat behaviour was studied under conflict situation. n-DPA, AOAA and piracetam increased significantly the main index of the tranquilizing action, that is the number of water intakes from the drinking bowl, supported by electric stimulation. This effect was most pronounced in n-DPA. Bicuculline and corasol almost completely eliminated the tranquilizing effect of n-DPA, while this effect was abolished by caffeine only by 50%.
D000085:Acetates / Q000494:pharmacology*; D000625:Aminooxyacetic Acid / Q000494:pharmacology*; D000818:Animals; D001640:Bicuculline / Q000494:pharmacology; D002110:Caffeine / Q000494:pharmacology; D003220:Conflict, Psychological; D008297:Male; D008960:Models, Psychological; D010205:Pantothenic Acid / Q000494:pharmacology*; D010433:Pentylenetetrazole / Q000494:pharmacology; D010889:Piracetam / Q000494:pharmacology*; D011760:Pyrrolidinones / Q000494:pharmacology*; D051381:Rats; D014149:Tranquilizing Agents; D014635:Valproic Acid / Q000037:antagonists & inhibitors / Q000494:pharmacology*
D000085:Acetates; D011760:Pyrrolidinones; D014149:Tranquilizing Agents; D000625:Aminooxyacetic Acid; D010205:Pantothenic Acid; D002110:Caffeine; D014635:Valproic Acid; D010433:Pentylenetetrazole; D001640:Bicuculline; D010889:Piracetam
Trankviliziruiushchiĭ éffekt n-kipropilatsetata i drugikh gamkergicheskikh veshchestv v usloviiakh konfliktnoĭ situatsii.