[Role of secretion in the dynamics of the maturation of predentin. Morphological, autoradiographic and freeze fracture study in the rat; changes induced by vinblastine].
Morphological and autoradiographic data give evidence that secretion take place at the odontoblast process level according to a lateral axis, perpendicular to the maturation axis of the predentine. Induced modifications with vinblastine sulphate emphasize the importance of the pericellular space (150--200 nm) while the disorganization of the collagen fiber arrangement suggests the presence of flows. We propose an hypothesis which connects all these facts.
D000818:Animals; D001345:Autoradiography; D003804:Dentin / Q000166:cytology / Q000378:metabolism*; D005614:Freeze Fracturing; D009804:Odontoblasts / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D014747:Vinblastine / Q000494:pharmacology*
D014747:Vinblastine
Rôle du flux sécréteur dans la dynamique de maturation de la prédentine. Etude morphologique, autoradiographique et par cryofracture chez le rat; modifications induites par la vinblastine.