[General effects of cytosine arabinoside on the embryo of reptiles].
Administered to eggs of Reptilia (Lacerta viridis and Anguis fragilis), cytosine-arabinoside induced numerous embryonic malformations, among which microphthalmia and limb deformities. On the other hand this drug delayed the retrogression of the apical ridge of the limb buds in Anguis fragilis.
D000014:Abnormalities, Drug-Induced / Q000196:embryology; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003561:Cytarabine / Q000009:adverse effects / Q000494:pharmacology*; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D017880:Limb Deformities, Congenital; D008116:Lizards / Q000196:embryology*; D008850:Microphthalmos / Q000139:chemically induced
D003561:Cytarabine
Effets généraux de la Cytosine-arabinofuranoside sur l'embryon des Reptiles.