Intrapartum fetomaternal bleeding in Rh-negative women.
In a series of 1206 consecutive Rh-negative women who delivered Rh-positive infants, fetal erythrocytes were found in the maternal blood of 175 (14.5%) during the postpartum period. In 12 (1.0%) there was evidence of a larger fetomaternal hamorrhage than would be neutralized by a single 300-microgram dose of Rh-immune globulin. Except for manual removal of the placenta, no correlation was found between large fetomaternal hemorrhages and obstetric manipulations, complications, or surgery. Thus, the authors believe that all Rh-negative patients should be screened post partum to ascertain the adequacy of Rh-immune globulin prophylaxis.
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D036861:Delivery, Obstetric; D005260:Female; D005312:Fetal Blood / Q000032:analysis / Q000276:immunology*; D005331:Fetomaternal Transfusion / Q000175:diagnosis / Q000517:prevention & control; D006801:Humans; D007116:Immunization, Passive; D010298:Parity; D049590:Postpartum Period; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D012204:Rh-Hr Blood-Group System