Mushrooms and madness. Hallucinogenic mushrooms and some psychopharmacological implications.
This article reviews the major hallucinogenic fungi both for their historical as well as neurochemical import. Despite voluminous literature on them, relatively little study has focused on psilocybin related substances that could relate to forms of psychotic illness. Some metabolic pathways are reviewed which illustrate the need for more study of indole compounds such as baeocystin.
D000545:Amanita / Q000032:analysis; D001487:Basidiomycota / Q000032:analysis*; D002621:Chemistry; D006166:Guatemala; D006213:Hallucinogens / Q000032:analysis* / Q000266:history; D049691:History, Medieval; D049711:History, Modern 1601-; D006801:Humans; D007194:India; D008800:Mexico; D008995:Monoamine Oxidase / Q000378:metabolism; D004130:N,N-Dimethyltryptamine / Q000378:metabolism; D010649:Phenylalanine / Q000378:metabolism; D012559:Schizophrenia / Q000209:etiology / Q000378:metabolism; D012800:Siberia; D014364:Tryptophan / Q000378:metabolism
D006213:Hallucinogens; D010649:Phenylalanine; D014364:Tryptophan; D008995:Monoamine Oxidase; D004130:N,N-Dimethyltryptamine