[Fluorescence histochemical and neurohistological investigations on the locus coeruleus of the rat (author's transl)].
The Locus coeruleus (LC) of the adult rat was investigated by means of fluorescence histochemical and rapid GOLGI impregantion technique. The majority of LC neurons displayed, as a result of application of the FALCK-HILLARP-technique and the LOREN-technique, resp, the well-known fluorescence typical of catecholamine neurons. There was lack of fluorescence within a minor portion of cells. Fluorescence histochemically, serotoninergic afferents could be shown to go up to noradrenaline-containing neurons in some cases. In the GOLGI material, 3 types of neurons could be distinguished: Polygonal neurons exhibiting somatic spines, fusiform neurons, and small-sized spine-less neurons. Based on morphological features, the polygonal neuron type is considered to represent the monoamine-containing neurons of the Locus coeruleus. It appears uncertain at present to attribute the fusiform and small spineless neuron types in a functional manner. functional implications inherent that morphological heterogeneity have been discussed.
D000818:Animals; D002395:Catecholamines / Q000032:analysis; D008125:Locus Coeruleus / Q000033:anatomy & histology*; D008297:Male; D008856:Microscopy, Fluorescence; D009474:Neurons / Q000032:analysis / Q000145:classification / Q000187:drug effects; D051381:Rats / Q000033:anatomy & histology*; D012110:Reserpine / Q000494:pharmacology; D012701:Serotonin / Q000032:analysis
D002395:Catecholamines; D012701:Serotonin; D012110:Reserpine
Fluoreszenzhistochemische und neurohistologische Untersuchungen am Locus coeruleus der Ratte.