Insulin receptors and syndromes of insulin resistance.
Whenever normal concentrations of insulin produce a biologic response that is less than normal, insulin resistance should be suspected. Insulin resistance may occur in many different disease states and may involve an entire organism, a single tissue or cell, or even a single metabolic pathway of insulin action. This report outlines current knowledge about the mechanism of insulin resistance, as well as specific examples of disease states in which it occurs.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D007333:Insulin Resistance; D009765:Obesity / Q000378:metabolism; D011972:Receptor, Insulin / Q000032:analysis* / Q000276:immunology
D000906:Antibodies; D007328:Insulin; D011972:Receptor, Insulin