Oxipor VHC lotion versus Tegrin in the treatment of psoriasis.
A double-blind, multiclinic, parallel, controlled study was conducted to compare the efficacy of two coal tar over-the-counter products, Oxipor VHC lotion and Tegrin lotion. The pooled analysis showed that both left and right sides of the body were comparable with respect to the initial severity of all clinical parameters including scaling, erythema, pruritus, crusting, and lesion elevations. Both test medications improved clinical symptoms significantly, but Oxipor VHC lotion was superior to Tegrin lotion in all clinical variables with the exception of crusting. Oxipor VHC was also significantly superior to Tegrin in terms of physicians' and patients' overall assessments.
D000481:Allantoin / Q000627:therapeutic use*; D001566:Benzocaine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003033:Coal Tar / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations / Q000627:therapeutic use; D006801:Humans; D011136:Polysorbates / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*; D012459:Salicylates / Q000627:therapeutic use*
D004338:Drug Combinations; C036569:Oxipor VHC; D011136:Polysorbates; D012459:Salicylates; C036568:tegrin; D000481:Allantoin; D003033:Coal Tar; D001566:Benzocaine