Capillary permeability of heterogeneous organs: a parsimonious interpretation of indicator diffusion data.
1. Calculations of capillary permeability of perfused organs from indicator diffusion data are reviewed, and reconsidered in terms of two kinds of organ heterogeneity of capillary extraction. 2. New expressions are derived for calculating the organ permeability-surface area product PS. In the simplest circumstances.
D000818:Animals; D001921:Brain / Q000098:blood supply; D002199:Capillary Permeability; D002250:Carbon Radioisotopes; D002560:Cerebrovascular Circulation; D003326:Coronary Circulation; D003331:Coronary Vessels; D004058:Diffusion; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007201:Indicator Dilution Techniques; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D010477:Perfusion; D011336:Probability; D012039:Regional Blood Flow; D013395:Sucrose / Q000378:metabolism; D014316:Tritium
D002250:Carbon Radioisotopes; D014316:Tritium; D013395:Sucrose; D005947:Glucose