Capping of DNA on phytohemagglutinin-stimulated human lymphoblasts.
A portion of the DNA released by PHA-stimulated human lymphoblasts becomes bound to the plasma membranes of the cells and is actively capped. Capping is accompanied by shape change, and caps are localized to uropods. DNA can be exchanged between cells for capping.
D000818:Animals; D000001:Calcimycin / Q000494:pharmacology; D002417:Cattle; D002465:Cell Movement; D004247:DNA / Q000276:immunology*; D006801:Humans; D007152:Immunologic Capping; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology*; D013997:Time Factors; D014357:Trypsin / Q000494:pharmacology
D010835:Phytohemagglutinins; D000001:Calcimycin; D004247:DNA; D014357:Trypsin