The relationship between the blood and vein wall fibrinolytic activities in response to surgical trauma.
The fibrinolytic response to surgical trauma was studied longitudinally in 7 pigs by measuring the fibrinolytic activity in the blood and vein wall simultaneously. The results indicated a marked suppression in fibrinolytic activity in the blood which was closely correlated with the activity in the vein wall. This correlation lends support to the hypothesis that the venous endothelium is the source of spontaneous fibrinolytic activity in the blood.
D000818:Animals; D001769:Blood / Q000378:metabolism*; D005342:Fibrinolysis; D008954:Models, Biological; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013552:Swine; D013997:Time Factors; D014680:Veins / Q000378:metabolism*