In vivo characteristics of thaw siphon cryoprecipitate compared to other factor VIII preparations.
5 severe haemophiliacs were infused with cryoprecipitate prepared by the continuous thaw-siphon technique, with cryoprecipitate prepared by overnight thawing and with intermediate-purity factor VIII concentrate. All 3 preparations gave a similar mean half-life for coagulant factor VIII of approximately 10 hours. The immediate recovery of this activity was similar for the 2 cryoprecipitates, but higher for the purified concentrate.
D000328:Adult; D005169:Factor VIII / Q000592:standards* / Q000627:therapeutic use; D005615:Freezing; D006207:Half-Life; D006467:Hemophilia A / Q000188:drug therapy; D006801:Humans; D008722:Methods
D005169:Factor VIII