[Nitroglycerin and anaesthesia in phaeochromocytoma (author's transl)].
Six patients who have undergone surgery for phaeochromacytoma have been separated in 2 groups. In group I (n = 3) a nitroglycerin infusion of 7.8 microgram . kg-1 . mn-1 has been used before the removal of the tumor and no vasodilator drug was infused in group II. During the dissection, mean arterial pressure was significantly lower in group I (129 +/- 12 mm Hg) than in group II (172 +/- 17 mm Hg) (p < 0.05). After removal of the tumor the decrease in mean arterial pressure was lower in group I than in group II. In group I the maximal rise in mean arterial pressure (73 +/- 18 mm Hg) was significantly reduced compared to group II (134 +/- 20 mm Hg). These results show that nitroglycerin is an interesting substance to decrease the variations of arterial blood pressure and this effect is important to prevent cardiac complications during and after surgery.
D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D000328:Adult; D000758:Anesthesia; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000627:therapeutic use*; D010673:Pheochromocytoma / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*
D005996:Nitroglycerin
Utilisation de la nitroglycérine au cours de la chirurgie du phéochromocytome.