A serotonin-immunoreactive fiber system in the dorsal columns of the spinal cord.
Serotonin-immunoreactive fibers have been observed in the dorsal columns of the golden hamster spinal cord. The fibers were visualized using the PAP method which was intensified with a DAB-nickel substrate. The fibers were arranged preferentially in the mid-sagittal plane, and many were observed coursing from the dorsal columns into the dorsal gray matter. This serotonin-immunoreactive pathway may play a role in analgesia produced by dorsal column stimulation.
D000818:Animals; D006224:Cricetinae; D005727:Ganglia, Spinal / Q000033:anatomy & histology*; D007124:Immunoenzyme Techniques; D008647:Mesocricetus; D009412:Nerve Fibers / Q000648:ultrastructure; D009434:Neural Pathways / Q000033:anatomy & histology; D012701:Serotonin / Q000378:metabolism*; D013116:Spinal Cord / Q000033:anatomy & histology*
D012701:Serotonin