[Serologic tests for syphilis--yesterday, today, tomorrow].
After an historical survey, the various modern serologic tests for syphilis are dealt with. The humoral immunological phenomena, which develop in a certain chronological order, antilipoidal (non-specific) and antitreponemal (specific) antibodies of the classes IgM and IgG are presented. Particularly the demonstration of specific antitreponemal antibodies of the IgM class has opened up new perspectives in the serologic diagnostics of syphilis. For the present, screening examinations and the confirmation of the diagnosis are the domain of the specific tests (TPHA, FTA), while for the assessment of the therapy effect and of reinfection the unspecific tests (VDRL) are still to be employed.
D000907:Antibodies, Bacterial / Q000276:immunology; D006386:Hemagglutination Tests; D049673:History, 20th Century; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D013587:Syphilis / Q000276:immunology; D013588:Syphilis Serodiagnosis / Q000266:history; D014208:Treponema / Q000276:immunology; D014209:Treponema Immobilization Test
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G
Lues-Serologie--gestern, heute und morgen.