[The influence of thioctic acid on the growth of Ehrlich ascites carcinoma (author's transl)].
Male and female NMRI mice received a daily dose of 100 mg/kg thioctic acid i.v., s.c., or i.p. for five days after transplantation with Ehrlich ascites carcinoma. Median survival time, increase in body weight, and volume and cellular content of the ascitic fluid were determined. Except a decrease in survival time which was due to the high dose of the thiotic acid but not to an increased growth of tumor cells, there was no significant difference between treated animals and control groups.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002286:Carcinoma, Ehrlich Tumor / Q000503:physiopathology*; D005260:Female; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D008063:Thioctic Acid / Q000494:pharmacology*; D013997:Time Factors; D014184:Transplantation, Homologous
D008063:Thioctic Acid
Einfluss von Thioctsäure auf das Wachstum von Ehrlich-Aszites-Karzinom.