Growth and biosynthesis of aflatoxin by Aspergillus parasiticus in cultures containing nisin.
Nisin, 200 or 5000 Reading units/ml, was added to Aspergillus parasiticus cultures. The cultures were incubated at 28 degrees C for 3, 7 or 10 days and analyzed for mycelial dry weight, pH and accumulation of aflatoxin B1 and G1. During the first 3 days of incubation, dry weight, pH decrease and aflatoxin accumulation were suppressed by nisin, when compared with similar values for the nisin-free control. After longer incubation, differences in dry weight nd pH values decreased, whereas accumulation of aflatoxin in the nisin-containing cultures surpassed that of the control.
D016604:Aflatoxin B1; D000348:Aflatoxins / Q000096:biosynthesis*; D001230:Aspergillus / Q000378:metabolism*; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D009561:Nisin / Q000494:pharmacology*
D000348:Aflatoxins; D003470:Culture Media; D009561:Nisin; C027955:aflatoxin G1; D016604:Aflatoxin B1