[Pathology of osteogenic sarcoma].
The problem of pathology (back-ground processes and pathogenetic mechanisms) of osteogenic sarcoma are discussed on the basis of the data from the literature and the author's own experimental and clinico-morphological data. The nature and essence of disorders of enchondral osteogenesis in laboratory animals and man preceding or accompanying the development of osteogenic sarcoma are considered. Correlations between the process of the skeleton growth, disturbances in osteogenesis, and emergence of bone tumors are discussed. A possible cell-tissue level at which tumor transformation occurs in the development of osteogenic sarcoma in long tubular bones is suggested.
D000293:Adolescent; D000328:Adult; D000818:Animals; D001846:Bone Development; D001859:Bone Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D004285:Dogs; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009381:Neoplasms, Radiation-Induced / Q000209:etiology / Q000473:pathology; D010012:Osteogenesis; D012516:Osteosarcoma / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D011627:Puberty; D011817:Rabbits; D051381:Rats; D012513:Sarcoma, Experimental / Q000209:etiology / Q000473:pathology
Patologiia osteogennoĭ sarkomy.