[Hypnotic effect of serotonin administered in the vago-aortic afferent pathway].
A minute amount of serotonin injected in the nodose ganglion circulation area develops abrupt myosis and general electrocortical synchronization activity in "encéphale isolé" Cat preparation. This hypnogenic effect of serotonin can still be reproduced after transection of vago-aortic nerves caudally to the nodose ganglia. The same injections become ineffective after rostral transection of the same pathway. These results suggest that serotonin may trigger some signs of sleep through peripheric nervous elements in which are probably localized in the nodose ganglia.
D000818:Animals; D001011:Aorta / Q000294:innervation; D002415:Cats; D003655:Decerebrate State; D009434:Neural Pathways / Q000187:drug effects; D009620:Nodose Ganglion / Q000187:drug effects* / Q000502:physiology; D010525:Peripheral Nerves / Q000187:drug effects; D012701:Serotonin / Q000008:administration & dosage / Q000494:pharmacology*; D012890:Sleep / Q000187:drug effects*; D014630:Vagus Nerve / Q000187:drug effects*
D012701:Serotonin
Effet hypnogène de la sérotonine par mise en jeu de la voie vago-aortique afférente.