[Effect of the female genotype on the yield of dominant lethal mutations induced by thiophosphamide in mature mouse spermia].
On crossing of thiophosphamide treated CBA males to untreated A/He, C57BL/6, C57BL/Mib and fidget females the lowest output of dominant lethal mutations was found in progeny of C57BL/Mib females. It is suggested that the ceparation of premutational lesions is most effective in egg cells of this strain.
D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005799:Genes, Dominant / Q000187:drug effects*; D005804:Genes, Lethal / Q000187:drug effects*; D005838:Genotype; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009154:Mutation; D013094:Spermatozoa / Q000187:drug effects*; D013852:Thiotepa / Q000494:pharmacology*
D013852:Thiotepa
Vliianie genotipa samok na vykhod dominantnykh letal'nykh mutatsiĭ, indutsirovannykh tiofosfamidom v zrelykh spermiiakh mysheĭ.