Immunohistochemical localization of IgG1 and IgG2 in prepartum and lactating bovine mammary tissue.
The differential distributions of IgG1 and IgG2 were determined in prepartum and lactating bovine mammary tissue by indirect immunofluorescence. IgG1 was found predominately within the alveolar epithelial cells and lumens of prepartum tissue whereas IgG2 was largely confined to the stromal area surrounding the alveoli. Both IgG subclasses were confined predominately to the stroma in lactating tissue. Few IgG containing stromal cells were readily distinguished in any of the mammary tissue used in this study.
D000818:Animals; D002417:Cattle; D005260:Female; D005455:Fluorescent Antibody Technique; D007074:Immunoglobulin G / Q000378:metabolism*; D007774:Lactation; D008321:Mammary Glands, Animal / Q000166:cytology / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal; D014018:Tissue Distribution
D007074:Immunoglobulin G