Use of captive-bred monkeys for vaccine production.
Cynomolgus monkeys (Macaca fasicularis) were bred in captivity for the production and control of inactivated poliomyelitis vaccine. Compared to imported wild-caught animals the captive-bred monkeys contracted fewer virus infections, as evidenced by results of serological examination, and yielded remarkably clean cell cultures. These cultures could be grown in series and appear very suitable for the production of viral vaccines.
D000818:Animals; D000835:Animals, Wild / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis*; D002478:Cells, Cultured; D005260:Female; D000882:Haplorhini; D008251:Macaca / Q000276:immunology*; D008252:Macaca fascicularis / Q000276:immunology*; D008297:Male; D051381:Rats; D014765:Viral Vaccines / Q000302:isolation & purification*
D000914:Antibodies, Viral; D014765:Viral Vaccines