[Enzymatic activities in the liver, and muscle nucleic acids, in swine receiving an unbalanced diet with an excess of methionine for 100 days].
Twelve growing Swine were fed an 18% protein diet (Maize and Soja bean) for one hundred days containing either 0,6% sulfur amino acids (basal diet) or 0,6% and 1% DL-methionine added to the control diet. Such an excess, reduced food intake and body weight gain mainly during the "finishing period" (60 to 100 kg). The RNA/DNA and protein/DNA ratios in the muscle did not show any difference. Hepatic activities of some enzymes involved in glycolysis, gluconeogenesis and amino acid metabolism, were unchanged, except that of methionine adenosyl transferase, the first step of transsulfuration, which was induced in proportion with the amount of the methionine ingested. Swine seemed to adapt to the excessive methionine intake, which did not show any toxicity in our experimental conditions.
D000818:Animals; D004032:Diet / Q000009:adverse effects; D005260:Female; D008099:Liver / Q000201:enzymology*; D008297:Male; D008715:Methionine / Q000633:toxicity*; D009132:Muscles / Q000378:metabolism*; D009696:Nucleic Acids / Q000378:metabolism*; D013552:Swine
D009696:Nucleic Acids; D008715:Methionine
Nutrition animale . -Activités enzymatiques dans le foie, at acides nucléiques musculaires, chez des porcs recevant pendant 100 jours une alimentation déséquilibrée par excès de méthionine.