Stress, personality and serum-cholesterol level.
It appears that serum-cholesterol level may serve as an important mediator between psychological variables and coronary heart disease (CHD). From a review of the literature it is concluded that (1) psychological stressors significantly elevate serum-cholesterol level and (2) psychological characteristics like the Type A-pattern and depression are positively correlated with serum-cholesterol levels. This suggests that the relationship between CHD and stress and coronary prone behavior may be partially explained by the mediating role of serum-cholesterol. A more careful consideration of psychological variables may be helpful in reducing the substantial amount of unexplained variance in cholesterol levels.
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000097:blood / Q000523:psychology; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D012306:Risk; D013315:Stress, Psychological / Q000097:blood*; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D002784:Cholesterol