Effect of pirenzepine in the treatment of non-ulcer dyspepsia. A double-blind study.
The effectiveness of pirenzepine at 50 mg daily in the treatment of non-ulcer dyspepsia was assessed in a double-blind 4-weeks clinical trial against placebo. 59 patients entered the trial of whom 11 defaulted or were withdrawn. 48 patients completed the trial. Clinical and laboratory assessment were performed on admission to the study and after 4 weeks treatment. The results of this double-blind comparative trial show that pirenzepine in a daily dose of 50 mg is very effective and significantly more effective than placebo in the treatment of non-ulcer dyspepsia.
D000328:Adult; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004415:Dyspepsia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D010890:Pirenzepine
D001570:Benzodiazepinones; D010276:Parasympatholytics; D010890:Pirenzepine