Vascular morphology in diabetic placentas.
Diabetic metabolism is reflected in the fetal blood and gives rise to diabetic angiopathy in the placenta. Capillary proliferation takes place with small newly formed vessels penetrating deeply into the trophoblast. Also signs of accelerated aging are found with thickening of the capillary basement membrane. Glycogen deposit/storage seems typical of diabetic placenta together with increased fibrosis. Uncertainty exists as to the degree of maturation of the trophoblast.
D001485:Basement Membrane / Q000473:pathology; D001786:Blood Glucose / Q000378:metabolism; D002196:Capillaries / Q000473:pathology; D002824:Chorionic Villi / Q000473:pathology; D003925:Diabetic Angiopathies / Q000473:pathology*; D004727:Endothelium / Q000473:pathology; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005333:Fetus / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D006801:Humans; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000098:blood supply* / Q000378:metabolism / Q000473:pathology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000378:metabolism / Q000473:pathology*
D001786:Blood Glucose; D006003:Glycogen