Sideroblastic anemia as a preleukemic event in patients treated for Hodgkin's disease.
Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation suggests that development of sideroblastic anemia in patients previously treated for Hodgkin's disease is probably secondary to the treatment and is a preleukemic event.
D000328:Adult; D000756:Anemia, Sideroblastic / Q000175:diagnosis / Q000209:etiology*; D000970:Antineoplastic Agents / Q000009:adverse effects; D004359:Drug Therapy, Combination; D006689:Hodgkin Disease / Q000150:complications* / Q000628:therapy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011289:Preleukemia / Q000175:diagnosis*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects
D000970:Antineoplastic Agents