Klebsiella pneumoniae enterotoxin. II. Physicochemical properties of enterotoxin.
Physicochemical properties and systemic effects of the enterotoxin of Klebsiella pneumoniae has been studied. The enterotoxin had a molecular weight between 10 000 to 50 000. It was protein in nature, and heat and acid stable, inducing a dilatatory response in the gut. It haemolyzed the erythrocytes of various animals including man. It had a capillary permeability activity. In addition, when administered parenterally it increased the level of blood glucose, serum cholesterol, serum alkaline phosphatase and serum acid phosphatase.
D000135:Acid Phosphatase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001426:Bacterial Proteins / Q000032:analysis; D001786:Blood Glucose / Q000378:metabolism; D002199:Capillary Permeability / Q000187:drug effects; D002784:Cholesterol / Q000097:blood; D004768:Enterotoxins / Q000032:analysis / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D007711:Klebsiella pneumoniae / Q000032:analysis*; D008970:Molecular Weight; D011817:Rabbits
D001426:Bacterial Proteins; D001786:Blood Glucose; D004768:Enterotoxins; D002784:Cholesterol; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase