An improved method using acetyl-coenzyme A regeneration for the enzymic inactivation of aminoglycosides prior to sterility testing.
D000105:Acetyl Coenzyme A / Q000378:metabolism / Q000494:pharmacology*; D000107:Acetylation; D000617:Aminoglycosides / Q000037:antagonists & inhibitors; D000900:Anti-Bacterial Agents / Q000037:antagonists & inhibitors; D004340:Drug Contamination; D004926:Escherichia coli / Q000201:enzymology; D005839:Gentamicins / Q000037:antagonists & inhibitors; D007612:Kanamycin / Q000037:antagonists & inhibitors; D008722:Methods; D009355:Neomycin / Q000037:antagonists & inhibitors; D010709:Phosphate Acetyltransferase / Q000378:metabolism; D013307:Streptomycin / Q000037:antagonists & inhibitors; D014031:Tobramycin / Q000037:antagonists & inhibitors
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005839:Gentamicins; D007612:Kanamycin; D000105:Acetyl Coenzyme A; D010709:Phosphate Acetyltransferase; D009355:Neomycin; D014031:Tobramycin; D013307:Streptomycin