The microscopical pattern of growth of Mycobacterium leprae-murium "Douglas" in microcolonies.
A thin section technique of Ogawa egg yolk culture medium inoculated with Mycobacterium leprae-murium was found to reveal microscopical growth of the strain which could not be demonstrated by macroscopical examination. A peculiar structure of the growth, characterized by many lytic spots different in size, was observed indicating the possible presence of a temperate phage which may interfere with the synthesis of nucleic acids needed for the active multiplication of M. leprae-murium.
D000818:Animals; D001431:Bacteriological Techniques; D002642:Chick Embryo; D003470:Culture Media; D051379:Mice; D009167:Mycobacterium lepraemurium / Q000254:growth & development*
D003470:Culture Media