Alkylation of T7 bacteriophage blocks superinfection exclusion.
Alkylation of T7 bacteriophage by methyl methane sulfonate blocked superinfection exclusion. This blockage could be correlated with a delay in the synthesis of phage-specific proteins. Therefore we conclude that protein synthesis directed by the primary infecting phage is required for efficient exclusion of superinfecting phage particles.
D000478:Alkylation; D004926:Escherichia coli; D008741:Methyl Methanesulfonate / Q000378:metabolism; D013604:T-Phages / Q000502:physiology*; D014764:Viral Proteins / Q000096:biosynthesis
D014764:Viral Proteins; D008741:Methyl Methanesulfonate