Colon cleansing regimens. A clinical study in 1200 patients.
The purgative effect of bisacodyl, anthraquinone glycosides (Cascara), and sodium picosulfate, alone or in combination with a saline purge and a tap water enema, was studied in 1200 patients. The cleansing effect was scored with regard to retained fecal residue evident on double-contrast studies of the colon. The combination of a contact laxative and a saline purge produced good cleansing effect in 52%-80% of the patients. With an additional tap water enema given 1 hour before the colon examination, however, 96% of the colons were clean. The taste and the effects of the cleansing systems were tolerated favorably by more than 90% of the patients. However, 17% reported restriction in work capacity on the day of bowel cleansing.
D000328:Adult; D000368:Aged; D001726:Bisacodyl; D002400:Cathartics; D002951:Citrates; D002986:Clinical Trials as Topic; D003106:Colon / Q000000981:diagnostic imaging*; D004733:Enema; D005260:Female; D006801:Humans; D008277:Magnesium Oxide; D008278:Magnesium Sulfate; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010847:Picolines; D011859:Radiography; D011897:Random Allocation; D031955:Rhamnus
D002400:Cathartics; D002951:Citrates; D009942:Organometallic Compounds; D010847:Picolines; D001726:Bisacodyl; D008277:Magnesium Oxide; D008278:Magnesium Sulfate; C005701:picosulfate sodium