Cocaine intoxication: massive oral overdose.
Massive cocaine intoxication is manifested by central nervous system stimulation (restlessness, tremors, convulsions) and then depression (respiratory and cardiovascular failure). A young man presented with new seizures and eventual development of status epilepticus, respiratory failure, and cardiovascular depression. Investigation revealed ingestion of cocaine-filled condoms which had ruptured in the gastrointestinal tract. Smuggling of illicit drugs via the oral-fecal route may lead to severe physiologic derangements if the container ruptures.
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage; D003042:Cocaine / Q000506:poisoning*; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced; D006801:Humans; D008297:Male; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000139:chemically induced
D000927:Anticonvulsants; D003042:Cocaine