Comparison of cochlear histopathology following two implant designs for use in scala tympani.
Two designs of intracochlear implants were evaluated for their histopathologic effects in the monkey ear. A molded electrode designed to fit the contour of the basal turn of the scala tympani tended to create basilar membrane fistulas and osseous spiral lamina fracture, along with relatively extensive loss of spiral ganglion cells in sites adjacent to the implant. A delicate, free-fit electrode induced local encapsulation but little or no mechanical damage and limited degeneration of spiral ganglion cells. Both electrode types occasionally induced changes in stria vascularis.
D000818:Animals; D001489:Basilar Membrane / Q000473:pathology; D003051:Cochlea / Q000473:pathology*; D003054:Cochlear Implants / Q000009:adverse effects*; D050723:Fractures, Bone / Q000473:pathology; D000882:Haplorhini; D011474:Prosthesis Design / Q000009:adverse effects*; D012533:Scala Tympani / Q000473:pathology; D013136:Spiral Ganglion / Q000473:pathology; D013137:Spiral Lamina / Q000293:injuries / Q000473:pathology