Effect of retinyl acetate feeding on the activity of testicular enzymes in young rats.
Feeding of excess vitamin A significantly increased the activity of beta-galactosidase and beta-glucuronidase without effecting the activity of acid and alkaline phosphatase in rat testicular homogenates. It is suggested that imbalance of vitamin A affects the normal process of spermatogenesis by altering the activity of lysosomal enzymes.
D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D004224:Diterpenes; D005696:Galactosidases / Q000378:metabolism*; D005966:Glucuronidase / Q000378:metabolism*; D008297:Male; D051381:Rats; D000084562:Retinyl Esters; D013737:Testis / Q000187:drug effects / Q000201:enzymology*; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000494:pharmacology; D001616:beta-Galactosidase / Q000378:metabolism*
D004224:Diterpenes; D000084562:Retinyl Esters; D014801:Vitamin A; C009166:retinol acetate; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005696:Galactosidases; D001616:beta-Galactosidase; D005966:Glucuronidase