Passage of chemicals into human and animal semen: mechanisms and significance.
This review will begin with a brief account of the secretory mechanisms operating in the male reproductive tract. The entry of the different chemicals will be dealt with; with separate reference to testicular fluids, epididymal plasma, prostatic and vesicular secretions, and whole semen. Examples will be given of a number of chemical substances capable of passing into the secretions of the male reproductive tract and semen, in man and in animals--antispermatogenic and antiandrogenic agents, industrial chemicals, chemotherapeutic drugs, food additives, etc. The review will end with a critical appraisal of the methods involved and the results obtained from analyses of various chemicals in semen.
D000327:Adsorption; D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism; D050260:Carbohydrate Metabolism; D002331:Carnitine / Q000378:metabolism; D004542:Ejaculation / Q000187:drug effects; D004822:Epididymis / Q000378:metabolism; D004880:Ergothioneine / Q000378:metabolism; D005837:Genitalia, Male / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D008297:Male; D010539:Permeability; D011506:Proteins / Q000378:metabolism; D051381:Rats; D012661:Semen / Q000378:metabolism*; D013093:Spermatogonia / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000378:metabolism; D015032:Zinc / Q000378:metabolism
D000900:Anti-Bacterial Agents; D012739:Gonadal Steroid Hormones; D011506:Proteins; D004880:Ergothioneine; D015032:Zinc; D002331:Carnitine