[Resorption of pharmacologic substances and oxygen by the myocardium following application into the pericardial cavity].
The epicardium as a biological substrate is able to absorb. We were able to observe the absorption of pharmacological substances and the physically dissolved oxygen as well as the gaseous oxygen after the application into the pericardial cavity by experiments in narcotised mini-pigs. The oxygen absorption by the epicardium led to the retrogression of an artificially caused myocardial ischemia.
D000042:Absorption; D000768:Anesthesia, General; D000818:Animals; D001285:Atropine / Q000008:administration & dosage* / Q000378:metabolism; D006591:Hexobarbital; D009206:Myocardium / Q000378:metabolism*; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D010313:Partial Pressure; D010496:Pericardium / Q000378:metabolism; D011188:Potassium / Q000008:administration & dosage* / Q000378:metabolism; D013552:Swine; D013556:Swine, Miniature
D001285:Atropine; D006591:Hexobarbital; D011188:Potassium; D010100:Oxygen
Resorption von pharmakologischen Substanzen und Sauerstoff durch das Myokard nach Applikation in den Perikardraum.