A human lymphocyte mitogen extracted from the extracellular slime layer of Pseudomonas aeruginosa.
Slime glycolipoprotein of Pseudomonas aeruginosa has been found to exert a mitogenic effect on human peripheral blood and cord blood lymphocytes. The optimal concentration of glycolipoprotein was shown to be in the range of 100--200 micrograms/ml, and maximal incorporation of [14C]thymidine was seen on the fourth day of lymphocyte cultures.
D005312:Fetal Blood / Q000166:cytology; D006023:Glycoproteins; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes; D008934:Mitogens / Q000302:isolation & purification*; D011552:Pseudomonas Infections / Q000276:immunology; D011550:Pseudomonas aeruginosa; D013936:Thymidine / Q000378:metabolism
D006023:Glycoproteins; D008934:Mitogens; D013936:Thymidine