Multiple Pacinian neurofibroma and relationship with the finger-tip arterio-venous anastomoses.
Multiple Pacinian neurofibromas involving the three phalanges of the ring finger of the left hand in a 60-year-old woman are described. The abnormal proliferation of Vater-Pacini corpuscles in various stages of differentiation was associated with marked changes of the glomus type of arterio-venous anastomoses of the finger-tip. The close relationship between the new proliferated Vater-Pacini corpuscles, their altered baresthetic function and the pathological shunting of blood account for the painful Raynaud-like symptoms. The name 'Pacinian neurofibromatosis' is proposed.
D001163:Arteriovenous Anastomosis / Q000473:pathology*; D005260:Female; D005385:Fingers / Q000098:blood supply* / Q000294:innervation; D006801:Humans; D008465:Mechanoreceptors / Q000473:pathology*; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000473:pathology*; D010141:Pacinian Corpuscles / Q000473:pathology*