Anti-androgenic action of cyproterone acetate in the epididymis of the rhesus monkey.
Cyproterone acetate (1 microM) inhibited the binding of labeled testosterone (T) and dihydrotestosterone (DHT) in the caput and cauda epididymides of the rhesus monkey. The same concentration of the anti-androgen failed to inhibit androgen binding in the ductus deferens, prostate and seminal vesicles.
D000818:Animals; D003534:Cyproterone / Q000494:pharmacology*; D013196:Dihydrotestosterone / Q000037:antagonists & inhibitors* / Q000378:metabolism; D004822:Epididymis / Q000187:drug effects / Q000378:metabolism; D005837:Genitalia, Male / Q000187:drug effects / Q000378:metabolism; D000882:Haplorhini; D008253:Macaca mulatta; D008297:Male; D013739:Testosterone / Q000037:antagonists & inhibitors* / Q000378:metabolism
D013196:Dihydrotestosterone; D013739:Testosterone; D003534:Cyproterone