Alloxan toxicity to the pancreatic B-cell. A new hypothesis.
D019325:3-O-Methylglucose; D000262:Adenylyl Cyclases / Q000378:metabolism; D000496:Alloxan / Q000037:antagonists & inhibitors / Q000633:toxicity*; D000818:Animals; D002241:Carbohydrates / Q000494:pharmacology; D002462:Cell Membrane / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology; D005609:Free Radicals; D005947:Glucose / Q000494:pharmacology; D006801:Humans; D007328:Insulin / Q000096:biosynthesis; D007515:Islets of Langerhans / Q000166:cytology / Q000187:drug effects*; D008757:Methylglucosides / Q000494:pharmacology; D010545:Peroxides / Q000633:toxicity
D002241:Carbohydrates; D005609:Free Radicals; D007328:Insulin; D008757:Methylglucosides; D010545:Peroxides; D019325:3-O-Methylglucose; D000496:Alloxan; D000262:Adenylyl Cyclases; D005947:Glucose