A conserved histone variant enriched in nucleoli of mammalian cells.
An antibody has been raised to Tetrahymena histone variant hv1 that specifically stains the macronucleus, but not the micronucleus, of Tetrahymena. This antiserum also stains small punctate regions in nucleoli of several mammalian cell lines. These observations suggest that this histone variant has been highly conserved in evolution and may be associated with transcribed sequences.
D000818:Animals; D002466:Cell Nucleolus / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D014644:Genetic Variation; D006657:Histones / Q000235:genetics*; D007106:Immune Sera; D013768:Tetrahymena / Q000235:genetics*; D014158:Transcription, Genetic
D006657:Histones; D007106:Immune Sera