Trifluorthymidine in the treatment of herpes simplex corneal ulcers. A clinical evaluation.
The treatment of herpetic corneal ulcerations with trifluorthymidine (F3T) has been evaluated in a clinical trial. F3T was found to be an effective antiviral agent for herpetic keratitis and a valuable alternative to idoxuridine (IDU)-therapy. Clinically IDU-resistent herpetic ulcers responded favourably to treatment with F3T.
D055598:Chemical Phenomena; D002621:Chemistry; D002986:Clinical Trials as Topic; D003320:Corneal Ulcer / Q000188:drug therapy*; D006561:Herpes Simplex / Q000188:drug therapy*; D006801:Humans; D007065:Idoxuridine / Q000627:therapeutic use; D007635:Keratitis, Dendritic / Q000188:drug therapy; D013936:Thymidine / Q000031:analogs & derivatives*; D014271:Trifluridine / Q000627:therapeutic use*
D007065:Idoxuridine; D014271:Trifluridine; D013936:Thymidine