Mediator-induced macrophage activation, as shown by enhanced cytotoxicity for tumor, requires macrophage surface fucose and sialic acid.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D005643:Fucose / Q000494:pharmacology*; D006168:Guinea Pigs; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D009439:Neuraminidase / Q000494:pharmacology; D012794:Sialic Acids / Q000494:pharmacology*; D005644:alpha-L-Fucosidase / Q000494:pharmacology; D001616:beta-Galactosidase / Q000494:pharmacology
D012794:Sialic Acids; D005643:Fucose; D009439:Neuraminidase; D001616:beta-Galactosidase; D005644:alpha-L-Fucosidase