[Giant cutaneous horn developed at the expense of a total orbital skin graft and rapidly evolving into an epithelioma].
The author reports a patient who at the age of 4 years presented a tumour of the left internal canthus thus which after many extirpations presented as many times recurrences. An intense radiotherapy put an end to the recurrences at the cost of the atrophy of the left eye and of the destruction of the periocular tissues. After 25 years necrosis of these periocular tissues necessitated the exenteration of the left orbit followed by a free skin graft. 12 years later on the floor of the left orbit developed a giant cutaneous horn which was extirpated. After 4 months a similar tumour grew on the medial wall of the orbit which developed rapidly filling the orbit and invading the maxillary and ethmoidal sinuses. The histological examination of the tumour showed the characteristics of a squamous cell epithelioma. The author discusses further the possible role of the area on which was transplanted the skin, the role of the irradiation and finally of the scarce vascularization of the this orbit, in the tumoral proliferation.
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000628:therapy; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D009918:Orbital Neoplasms / Q000209:etiology / Q000473:pathology*; D011183:Postoperative Complications; D011230:Precancerous Conditions / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology*; D016038:Skin Transplantation
Corne cutanée géante développée aux dépens d'une greffe de peau totale de l'orbite et évoluant rapidement vers l'épithélioma.