Effect of thiamphenicol on iron absorption.
The effect of thiamphenicol (a protein synthesis inhibitor) administration on iron absorption was studied in rabbits. Iron absorption was measured in a whole-body counter using 59Fe, and plasma iron turnover (PIT) was simultaneously determined with 55Fe. In comparison with the controls, the group receiving thiamphenicol showed no significant difference in PIT (p > 0.05), while iron absorption was increased (p < 0.0001).
D000818:Animals; D007408:Intestinal Absorption / Q000187:drug effects*; D007501:Iron / Q000097:blood / Q000378:metabolism*; D014176:Protein Biosynthesis; D011817:Rabbits; D013839:Thiamphenicol / Q000494:pharmacology*
D007501:Iron; D013839:Thiamphenicol