A double-blind trial of clomipramine in premature ejaculation.
A double-blind clinical trial was designed to study the effect of clomipramine in 50 patients complaining of rapid ejaculation. Patients were divided into two groups and each group received 2 periods of 6 consecutive weeks' treatment with drug and placebo, so that comparison can be made between drug and placebo within each group and between the two groups. Analysis of collected data showed a significantly higher percentage of satisfactory performances with the drug than with placebo and maintenance of the beneficial effect after the drug was replaced by placebo.
D000328:Adult; D002986:Clinical Trials as Topic; D002997:Clomipramine / Q000627:therapeutic use*; D004311:Double-Blind Method; D004542:Ejaculation / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy*
D002997:Clomipramine