[Serologic hepatitis B markers in porphyria cutanea tarda (author's transl)].
Using several seromarkers for hepatitis B virus the frequency of previous hepatitis B in patients with porphyria cutanea tarda (PCT) as a possible manifestation factor was determined. As chronic hepatitis is frequently associated with an increase of factor VIII-associated antigen, this was included in the investigation. Results make it likely that 28 out of 60 investigated patients (47%) have had hepatitis. In 30% an increase of factor VIII-associated antigen was found. It can be assumed that hepatitis B virus infection as a manifestation factor may be of considerable importance in porphyria cutanea tarda when genetic disposition (uroporphyrinogen-decarboxylase deficiency) is present.
D000941:Antigens / Q000032:analysis*; D005169:Factor VIII / Q000276:immunology*; D005260:Female; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D008297:Male; D011164:Porphyrias / Q000150:complications / Q000276:immunology*; D012871:Skin Diseases / Q000276:immunology*
D000941:Antigens; D005169:Factor VIII
Serologische Hepatitis-B-Marker bei Porphyria cutanea tarda.