The scope of hyaluronic acid as an experimental intraocular implant.
The inflammatory potential of hyaluronic acid (HA) varies from batch to batch of HA independent of tissue origin, concentration, or amino acid composition. The inflammatory potential can be determined by intravitreous testing only, not by intracameral testing. Retention of HA in the eye depends on molecular weight and concentration of HA, not on the ocular inflammatory response. Concentration, molecular weight, and inflammatory grade of any HA batch used in intraocular surgery should be specified. Monitoring of the postoperative intraocular pressure is recommended.
D000818:Animals; D001082:Aqueous Humor / Q000032:analysis; D005136:Eye Proteins / Q000032:analysis; D000882:Haplorhini; D006820:Hyaluronic Acid / Q000009:adverse effects* / Q000032:analysis; D007249:Inflammation / Q000209:etiology; D007429:Intraocular Pressure / Q000187:drug effects; D008970:Molecular Weight; D014822:Vitreous Body / Q000032:analysis / Q000601:surgery
D005136:Eye Proteins; D006820:Hyaluronic Acid