Comparison of salbutamol given by intermittent positive-pressure breathing and pressure-packed aerosol in chronic asthma.
A double-blind crossover study was performed to compare 4 . 8 mg salbutamol given by pressure-packed aerosol and intermittent positive-pressure breathing nebulization in chronic asthmatic patients. The two delivery techniques produced similar changes in respiratory function and pulse rates. Given equal effect, a high-dose pressure-packed aerosol would have advantages in cost and convenience over nebulization techniques.
D000336:Aerosols; D000420:Albuterol / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008875:Middle Aged; D012129:Respiratory Function Tests
D000336:Aerosols; D000420:Albuterol