Metabolic sequelae of experimental leptospirosis in grivet monkeys.
Leptospira interrogans serovars balcanica and tarassovi both induced mild subclinical infections in grivet monkeys. The activities in serum of lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase, aspartate aminotransferase, alanine aminotransferase and creatine phosphokinase and the level of alpha 1-antichymotrypsin increased in a few days after infection. Concomitant decreases in serum iron levels were observed in some cases. These changes occurred in the absence of any observable clinical signs though there were histopathological lesions in some organs. No haematological changes or alterations in other sreum components were detected.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism; D002521:Cercopithecus; D003402:Creatine Kinase / Q000097:blood; D000882:Haplorhini; D006884:Hydroxybutyrate Dehydrogenase / Q000097:blood; D007501:Iron / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007921:Leptospira interrogans; D014895:Weil Disease / Q000097:blood* / Q000201:enzymology; D015032:Zinc / Q000097:blood
D001798:Blood Proteins; D007501:Iron; D007770:L-Lactate Dehydrogenase; D006884:Hydroxybutyrate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase; D015032:Zinc