Efficacy and toxicity of retreatment with gold salts: a retrospective review of 25 cases.
We reviewed the records of 24 patients with rheumatoid arthritis who underwent 25 retreatments with gold salt injections given at a frequency greater than the usual monthly maintenance. Subject to the limitations of retrospective review, it was judged that every patient had improved on retreatment (5 fair, 19 good, 1 excellent), and there was only 1 instance of toxicity necessitating cessation of chrysotherapy. Repeat courses of gold salt injections of increased frequency appears to be a safe and effective therapeutic option for patients with rheumatoid arthritis who relapse after initial successful treatment.
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D006051:Aurothioglucose / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D006046:Gold / Q000627:therapeutic use*; D006052:Gold Sodium Thiomalate / Q000627:therapeutic use* / Q000633:toxicity; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
D006052:Gold Sodium Thiomalate; D006051:Aurothioglucose; D006046:Gold