Cromolyn sodium in the treatment of ulcerative colitis.
An immediate hypersensitivity reaction with mast cell degranulation may be of importance in the pathogenesis of ulcerative colitis. Cromolyn sodium stabilizes the mast cell membrane, and thus could have potential benefit in the treatment of this disease. The few clinical studies published to date are difficult to interpret, and have not established the therapeutic benefit of cromolyn sodium in ulcerative colitis.
D002462:Cell Membrane / Q000187:drug effects / Q000276:immunology; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000188:drug therapy; D008407:Mast Cells / Q000473:pathology
D004205:Cromolyn Sodium