Abnormal lysozyme production of peritoneal macrophages from mastocytoma P-815 bearing C3D2F1-mice.
Sodium thioglycollate-induced peritoneal macrophages from C3D2F1 mice were examined for their ability to produce and secrete lysozyme in vitro. Lysozyme was quantitated by use of a "lysoplate assay", in which lyophilized Micrococcus lysodeicticus suspended in agar were lysed by the enzyme. The ability to secrete lysozyme decreased in mice bearing a subcutaneous or intraperitoneal mastocytoma P-815 with progressive tumour growth.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology / Q000187:drug effects; D002478:Cells, Cultured; D008264:Macrophages / Q000201:enzymology*; D012515:Mast-Cell Sarcoma / Q000201:enzymology*; D051379:Mice; D009113:Muramidase / Q000096:biosynthesis*; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000201:enzymology; D013864:Thioglycolates / Q000494:pharmacology
D013864:Thioglycolates; D009113:Muramidase