Radiographic findings in congenital lead poisoning.
Because lead crosses the placenta throughout pregnancy, the fetus is at risk for lead poisoning. A full term, asymptomatic child was born with congenital lead poisoning secondary to maternal pica. Radiographic findings of a dense cranial vault, lead lines, and delayed skeletal and deciduous dental development were noted at birth. After chelation therapy, when the patient was seven months old, radiographs revealed normal skeletal maturation. Tooth eruption did not occur until 15 months of age. Newborn infants with these radiographic findings should be screened for subclinical, congenital lead poisoning.
D000293:Adolescent; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002118:Calcium / Q000627:therapeutic use; D004492:Edetic Acid / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007855:Lead Poisoning / Q000151:congenital / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008431:Maternal-Fetal Exchange; D010842:Pica; D011247:Pregnancy; D011248:Pregnancy Complications; D011859:Radiography
D004492:Edetic Acid; D002118:Calcium