Calculating the dose of factor VIII in the management of haemophilia.
Three methods of calculating the dose of factor VIII have been compared. A simple formula based on body weight has been found satisfactory for cryoprecipitate and freeze-dried concentrate; but where body fluid build departs markedly from average, height should probably also be taken into account. Modifications for children are noted.
D000328:Adult; D001835:Body Weight; D002648:Child; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005169:Factor VIII / Q000008:administration & dosage*; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans
D005169:Factor VIII