title: [Pathobiochemistry of mineral and trace elements. III. Magnesium concentration in whole blood and serum of pregnant women and newborn (author's transl)].
abstract: Magnesium is a constitutional or additive component in over 200 enzymes: its significance in physiological or pathophysiological metabolism is therefore considerable. For this reason this element was also included on our program of studies on cation kinetics in pregnant women and in neonates. The results of our analyses of 158 gravid women with normal and toxic pregnancies can be summarized as follows: 1. Compared with the corresponding values for non-pregnant women, the mother's magnesium during a normal pregnancy is reduced up to 9.2% in the serum and, likewise significantly reduced in whole blood up to 7% of normal values. The same conditions apply to the newborn as well. During a pathological pregnancy the magnesium in serum is reduced by 6.3% and in whole blood 6.6% as opposed to non-pregnant women. 2. Serum magnesium decline is equally great for primi- as well as multipara. 3. The blood group of the pregnant women is without influence on the magnesium concentration. 4. The rhesus factor has no influence on the course of the magnesium concentration during pregnancy. 5. The reduction of the magnesium values in whole blood is significantly greater for newborn males than for newborn females. 6. A concrete statement about the extent to which magnesium affects the Apgar values cannot be made on the basis of the data analysed in these studies due to the lack of symmetry between the groups to be compared: groups 5-7 to 8-10. Further comparative studies are required for this. 7. Magnesium changes in mother and child correlate with pregnancy toxicoses and other parameters.
mesh_terms: D000328:Adult; D001789:Blood Group Antigens; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008274:Magnesium / Q000097:blood*; D008297:Male; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System; D012737:Sex Factors
chemical_list: D001789:Blood Group Antigens; D012204:Rh-Hr Blood-Group System; D008274:Magnesium
vernacular_title: Pathobiochemie von Mineral- und Spurenelementen. III Magnesiumkonzentration im Vollblut und Serum von Schwangeren und Neugeborenen.