Ultrasonically determined menstrual age as an indicator of fetal lung maturity.
The usefulness of ultrasonically determined menstrual age as a predictor of fetal lung maturity has been evaluated in patients without fetal or maternal disease undergoing repeat cesarean section. The menstrual age of each fetus was determined at 18-32 wk using biparietal diameter (BPD) measurements and previously established BPD growth curves. Lung maturity prior to delivery was assessed by measuring the lecithin/sphingomyelin (L/S) in amniotic fluid. The menstrual age at the time of the amniocentesis was derived by extrapolation from the results of the first scan. When the Sabbagha Composite BPD growth curve was used for menstrual age determinations, the L/S was less than 2.0 in all cases before 34 wk, both less than 2.0 and greater than or equal to 2.0 between 34 and 38 wk, and greater than or equal to 2.0 in all but one case after 38 wk. This one case represents 1.2% of fetuses studied. These results suggest that in the absence of fetal and maternal disease, a menstrual age of 38 wk or older, based on an early BPD measurement and use of the Sabbagha Composite BPD growth curve, is indicative of lung maturity in most cases.
D005260:Female; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000196:embryology*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D014465:Ultrasonics