title: [Apropos of a case of idiopathic cryoagglutininemia with cryoglobulinemia and bone marrow lymphoplasmacytoid infiltration].
abstract: A case of idiopathic cryoagglutininaemia, with cryoglobulinaemia and lymphoplasmacytoid infiltration of the bone marrow is reported. The case is not held to be an independent clinical entity but an aspect of immunoproliferative disease, similar to Waldenstrom's disease. An association of steroids in high doses and cyclophosphamide led to a definite improvement in the clinical and haematological picture and this has continued for the past 4 years with little or no treatment.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000188:drug therapy; D000788:Angina Pectoris, Variant / Q000150:complications; D001854:Bone Marrow Cells; D003449:Cryoglobulinemia / Q000150:complications*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008214:Lymphocytes; D008297:Male; D008623:Mercaptoethanol / Q000627:therapeutic use; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications*; D010950:Plasma Cells
chemical_list: D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D008623:Mercaptoethanol
vernacular_title: A proposito di un case di crioagglutininemia idiopatica, con crioglobulinemia ed infiltrazione linfoplasmacitoide midollare.