title: Chemical modification of Lactobacillus casei thymidylate synthetase with 1-fluoro-2,4-dinitrobenzene and 1,5-difluoro-2,4-dinitrobenzene.
mesh_terms: D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D003432:Cross-Linking Reagents / Q000494:pharmacology; D003545:Cysteine; D004139:Dinitrofluorobenzene / Q000031:analogs & derivatives / Q000494:pharmacology*; D005459:Fluorides; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000201:enzymology*; D046911:Macromolecular Substances; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D009578:Nitrobenzenes / Q000494:pharmacology*; D012694:Serine; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors*
chemical_list: D003432:Cross-Linking Reagents; D046911:Macromolecular Substances; D009578:Nitrobenzenes; D012694:Serine; D004139:Dinitrofluorobenzene; D008780:Methyltransferases; D013940:Thymidylate Synthase; C002041:1,5-difluoro-2,4-dinitrobenzene; D003545:Cysteine; D005459:Fluorides