title: [Isolation and characterization of Escherichia coli strains sensitive to hydrophilic and/or charged antibiotics and toxics (author's transl)].
abstract: Two Escherichia coli mutant strains sensitive to antitumor derivatives of ellipticinium, ethidium bromide and to a variety of hydrophilic antibiotics and toxics have been isolated. The two mutations have been mapped on the bacterial chromosome at 5 +/- 1 and 10 +/- 1 mn respectively. Some properties of these strains are described and their interest in mutagen testing is discussed.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D005838:Genotype; D009154:Mutation; D010641:Phenotype; D013045:Species Specificity
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Isolement et caractérisation de souches d'Escherichia coli sensibles à des antibiotiques et des toxiques hydrophiles et/ou chargés.