title: Mass spectrometry in anesthesia. Problems in using mass spectrometer for monitoring anesthetic gases and vapours.
abstract: The use of mass spectrometers for total gas monitoring during anesthesia presents a number of problems which stem from the Cracking Pattern of the gases present, inlet design, viscosity variations, water vapour and machine deterioration. Some of these have been adequately solved, by making mechanical modifications to the inlet system, and by using more complex electronic circuitry to process the signals obtained. Remaining problems, however, still limit accuracy and ease of operation. CO2 measurements are particularly prone to error, especially when sampling halothane-containing gas which leads to significant internal production CO2. A study of the principal sources of error remaining in the machine suggests that the only definitive solution is to develop a microprocessor system which could cope with complex Cracking Patterns and non-linearities, and which would allow complete automation of the calibration procedure.
mesh_terms: D000777:Anesthetics / Q000032:analysis*; D002138:Calibration; D002245:Carbon Dioxide / Q000032:analysis; D005740:Gases / Q000032:analysis; D013058:Mass Spectrometry / Q000592:standards*
chemical_list: D000777:Anesthetics; D005740:Gases; D002245:Carbon Dioxide