[Postoperative analgesia with lysine salicylate and pentazocine].
The analgesic effect of two doses (1.8 and 3.6 g) of acetylsalicylate of lysine and two doses (30 and 60 mg) of pentazocine was studied after random administration to 40 patients who had undergone cholecystectomy. The experimental pattern was a four-point bio-assay and pain intensity was assessed on a 0 to 100 algesimetric scale by the patients themselves upon administration of the analgesic and after 30, 60 and 120 minutes. The analgesic of acetylsalicylate of lysine proved dose-dependent with a power ratio with respect to pentazocine of between 43 and 65.
D000328:Adult; D000368:Aged; D001241:Aspirin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002763:Cholecystectomy; D005260:Female; D006801:Humans; D008239:Lysine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D010423:Pentazocine / Q000627:therapeutic use*
D008239:Lysine; D001241:Aspirin; D010423:Pentazocine; C010395:acetylsalicylic acid lysinate
Analgesia post-operatoria con acetilsalicilato di lisina e pentazocina.