Uptake of 3,4-dihydroxy[3H]phenylalanine by Mycobacterium leprae isolated from frozen (-80 degrees C) armadillo tissue.
Mycobacterium leprae separated from armadillo tissues stored at -80 degrees C is similar to that from human sources in its ability to take up 3H-labelled 3,4-dihydroxyphenylalanine (DOPA). Several inhibitors were studied which showed complete or partial inhibition of [3H]DOPA uptake. These findings suggest that M. leprae isolated from frozen tissue possesses an active uptake system for [3H]DOPA.
D000818:Animals; D001135:Armadillos / Q000382:microbiology*; D001205:Ascorbic Acid / Q000494:pharmacology; D002614:Chelating Agents / Q000494:pharmacology; D004295:Dihydroxyphenylalanine / Q000378:metabolism*; D009166:Mycobacterium leprae / Q000378:metabolism*; D013154:Spleen / Q000382:microbiology; D013696:Temperature; D004490:Xenarthra / Q000382:microbiology*
D002614:Chelating Agents; D004295:Dihydroxyphenylalanine; D001205:Ascorbic Acid