title: Biotransformation and toxicity of aniline and aniline derivatives of cyanobacteria.
abstract: Agmenellum quadruplicatum strain PR-6 and Oscillatoria sp. strain JCM grown photoautotrophically in the presence of aniline metabolized the aromatic amine to formanilide, acetanilide and p-aminophenol. The metabolites were isolated by either thin-layer, gas-liquid or high pressure liquid chromatography and identified by comparison of their chromatographic, ultraviolet absorbance and mass spectral properties with those of authentic compounds. The toxicity of aniline derivatives towards Agmenellum quadruplicatum strain PR-6 indicated that the cyanobacterium was extremely sensitive to o-, m- and p-aminophenols, and phenylhydroxylamine.
mesh_terms: D000814:Aniline Compounds / Q000378:metabolism* / Q000633:toxicity; D000458:Cyanobacteria / Q000187:drug effects / Q000378:metabolism*
chemical_list: D000814:Aniline Compounds