title: Trace metal requirements in total parenteral nutrition: a theoretical approach by mathematical modeling.
abstract: A new computer-based approach has been developed to assess the optimal doses of essential trace metal ions which should be included in nutritive mixtures, used in human total parenteral nutrition, to compensate for the ligand-induced losses of these metal ions. An example of application is given for zinc, copper and manganese.
mesh_terms: D002118:Calcium / Q000008:administration & dosage; D003201:Computers; D003300:Copper / Q000008:administration & dosage; D006801:Humans; D008274:Magnesium / Q000008:administration & dosage; D008345:Manganese / Q000008:administration & dosage; D008670:Metals / Q000008:administration & dosage*; D008954:Models, Biological; D009751:Nutritional Requirements; D010288:Parenteral Nutrition; D015032:Zinc / Q000008:administration & dosage
chemical_list: D008670:Metals; D008345:Manganese; D003300:Copper; D008274:Magnesium; D015032:Zinc; D002118:Calcium