Mutagenicity of some contraceptive drugs in Drosophila melanogaster.
Combinations of 3 progestins, ethynodiol diacetate, norethynodrel and norgestrel, and 2 oestrogens, ethinyloestradiol and mestranol, were fed to larval Oregon-R fruit flies. None of the steroids studied induced X-linked recessive lethal mutations above the control level in Drosophila melanogaster.
D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics; D045166:Estradiol Congeners / Q000494:pharmacology*; D005260:Female; D005804:Genes, Lethal; D005808:Genes, Recessive; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens; D045167:Progesterone Congeners / Q000494:pharmacology*
D045166:Estradiol Congeners; D009153:Mutagens; D045167:Progesterone Congeners