[Prevention of peritoneal adhesions. An experimental study using noxytiolin (author's transl)].
Numerous procedures have been used to try to prevent peritoneal adhesions following operations. Noxytiolin has been used experimentally in the rat in a double blind trial on 3 series of 30 rats. A reliable procedure for making adhesions is said to be always reproducible. Comparing two control groups this study shows that statistically significantly this product lessens the number and seriousness of adhesions that can form, although it does not totally stop them developing.
D000818:Animals; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D009677:Noxythiolin / Q000627:therapeutic use*; D010532:Peritoneal Diseases / Q000517:prevention & control*; D051381:Rats; D011919:Rats, Inbred Strains; D013890:Thiourea / Q000031:analogs & derivatives*; D000267:Tissue Adhesions / Q000473:pathology / Q000517:prevention & control
D009677:Noxythiolin; D013890:Thiourea
Prévention de adhérences péritonéales. Etude expérimentale de la Noxytioline.