title: [Modern aspects of nitro preparation use].
abstract: On the basis of clinical examination and the results of bicycle ergometry and echocardiography in 58 patients with chronic ischemic heart disease the authors determined the contingent of patients in whom long-acting nitrates were most effective. The high clinical effectiveness of the agents in patients with symptoms of the initial stage of cardiac insufficiency is proved and the absence of any essential differences between long-acting nitrates in the character of their effect on hemodynamics is shown. It is established that nitroglycerin and long-acting nitrates cause a qualitatively similar effect on myocardial contractile function and intracardiac hemodynamics in patients with ischemic heart disease.
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy; D002317:Cardiovascular Agents; D002908:Chronic Disease; D003327:Coronary Disease / Q000188:drug therapy; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use; D009574:Nitro Compounds / Q000627:therapeutic use*; D005996:Nitroglycerin / Q000627:therapeutic use
chemical_list: D002317:Cardiovascular Agents; D003692:Delayed-Action Preparations; D009566:Nitrates; D009574:Nitro Compounds; D005996:Nitroglycerin
vernacular_title: Sovremennye aspekty primen eniia nitropreparatov.