Immunoglobulin allotypes and immune response to meningococcal group B polysaccharide.
Serum samples were collected from 120 healthy adult volunteers (105 Caucasians and 15 Negros) before and after immunization with meningococcal polysaccharide (MPS) group B vaccine. Antibodies to MPS group B were measured and sera were typed for several Gm and Km(1) allotypes. A significant association was found between the Km(1) allotype and immune response to MPS group B in Caucasians.
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D044383:Black People; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000032:analysis*; D008070:Lipopolysaccharides / Q000276:immunology*; D008297:Male; D009345:Neisseria meningitidis / Q000276:immunology*; D010641:Phenotype; D044465:White People
D007126:Immunoglobulin Allotypes; D008070:Lipopolysaccharides