Alpha-chain disease, schistosomiasis and toxoplasmosis: a case report in Brazil and follow-up for 5 years.
A case of alpha-chain disease associated with schistosomiasis mansoni and radiological and immunological findings suggestive of toxoplasmosis is reported. This patient has been followed-up for five years and is in clinical remission while taking tetracycline, prednisone and cyclophosphamide. This first report of alpha-chain disease in Brazil emphasizes certain common features of the various report of alpha-chain disease like the low socio-economic background of all individuals, and all living in areas where parasitic infections are endemic. A discussion of the probable etiopathogenesis of the disease is also presented.
D000293:Adolescent; D001774:Blood Chemical Analysis; D001938:Brazil; D005500:Follow-Up Studies; D006362:Heavy Chain Disease / Q000150:complications*; D006801:Humans; D007137:Immunoglobulin alpha-Chains; D007408:Intestinal Absorption; D007583:Jejunum / Q000473:pathology; D008297:Male; D012552:Schistosomiasis / Q000150:complications*; D014123:Toxoplasmosis / Q000150:complications*
D007137:Immunoglobulin alpha-Chains