[Anti-elastase of human pancreas: preparation and biological interest].
The present paper deals with the use of a new technique in type II human pancreatic elastase studies based on the use of a reversible immune-adsorbent which provides a unique specificity. According to the type of ligand linked on activated Sepharose, the elastase or its antibody in Rabbit could be obtained, in very pure form, in a one step process. The anti-human pancreatic elastase II, which specifically inhibits the enzyme, may be used in therapy whenever the elastase-inhibitor system becomes unbalanced.
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification*; D002846:Chromatography, Affinity; D006801:Humans; D007118:Immunoassay; D005779:Immunodiffusion; D010179:Pancreas / Q000201:enzymology*; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors / Q000276:immunology*; D011817:Rabbits / Q000276:immunology
D000906:Antibodies; D010196:Pancreatic Elastase
L'anti-élastase de pancréas humain; préparation et intérêt biologique.