title: Sympathectomy does not alter the response of carotid chemoreceptors to hypoxemia during carboxyhemoglobinemia or anemia.
abstract: We tested the effects of section of the sympathetic innervation to the carotid body on the responses of single carotid chemoreceptor fibers to carboxyhemoglobinemia (40-50%) and anemia (15-20% Hct) at various levels of paO2 (range: 20-450 Torr). Sympathectomy had virtually no effect on the steady-state response curves of carotid chemoreceptors to O2, either in normal cats or in those with reduced oxygen transport due to anemia or carboxyhemoglobinemia.
mesh_terms: D000200:Action Potentials; D000740:Anemia / Q000150:complications / Q000503:physiopathology*; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D002263:Carboxyhemoglobin / Q000032:analysis*; D002344:Carotid Body / Q000503:physiopathology*; D002415:Cats; D002628:Chemoreceptor Cells / Q000503:physiopathology*; D006454:Hemoglobins / Q000032:analysis*; D000860:Hypoxia / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D010100:Oxygen / Q000097:blood; D013562:Sympathectomy
chemical_list: D006454:Hemoglobins; D002245:Carbon Dioxide; D002263:Carboxyhemoglobin; D010100:Oxygen