title: Oral mannitol as a preparation for double contrast barium enema.
abstract: A oral mannitol purgative which is used prior to colonoscopy proved disappointing for barium enema preparation. A number of ways of improving bowel clearance with mannitol in divided dosage, preliminary oral metoclopramide and a clear fluid diet have been assessed. Divided dosage and a clear fluid diet were both beneficial, whereas oral metoclopramide was ineffective. Using the best regime, 38% of patients had a totally clear bowel compared with 33% using an established lavage technique. It is concluded that oral mannitol, with a clear fluid diet, is a satisfactory preparation for double contrast barium enema, and a regime is recommended.
mesh_terms: D000284:Administration, Oral; D001466:Barium Sulfate; D002400:Cathartics / Q000008:administration & dosage / Q000494:pharmacology*; D004032:Diet; D004733:Enema / Q000379:methods*; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008353:Mannitol / Q000008:administration & dosage / Q000494:pharmacology*; D008787:Metoclopramide / Q000627:therapeutic use; D007507:Therapeutic Irrigation; D013997:Time Factors
chemical_list: D002400:Cathartics; D001466:Barium Sulfate; D008353:Mannitol; D008787:Metoclopramide