[Effect of pH, pCO2, and pO2 on renal artery contractility and reactivity].
In isolated segments of the dog and cat renal arteries alkalization of the bathing solution at pH from 6.5 to 8.0 increased the amplitude of contraction and the sensitiveness to noradrenaline. A sharp rise of O2 content induced some increase in reactivity of muscle cells and caused spontaneous rhythmic activity. The results suggest a direct effect of pH and pO2 on the functional characteristics of renal arterial muscles. The effect seems to occur due to reversible changes in intracellular pH.
D000818:Animals; D002245:Carbon Dioxide; D002415:Cats; D004285:Dogs; D006863:Hydrogen-Ion Concentration; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology; D010100:Oxygen; D012077:Renal Artery / Q000187:drug effects / Q000502:physiology*; D014661:Vasoconstriction
D002245:Carbon Dioxide; D010100:Oxygen; D009638:Norepinephrine
Vliianie pH, pCO2, i pO2 na sokratimost' i reaktivnost' pochechnykh arteriĭ.