title: Gas exchange and respiratory mechanics during hip arthroplasty.
abstract: Gas exchange and respiratory mechanics were studied during hip arthroplasty, according to Charnley (1961). Dead space measurements were made by capnography and thoracic compliance and resistance, calculated from tracheal pressure variations and respiratory gas flow. PaO2 fell by 2.5 kPa with the insertion of each prosthesis. Small increases in PaCO2 were also seen. Distal (approximately corresponding to alveolar) dead space increased by 25% when each prosthesis was anchored. Dynamic thoracic compliance fell by 30-40 ml/kPa at the insertion of either prosthesis, while inspiratory and expiratory resistance were unaffected. The findings may indicate interference with the functions of both the bronchial and the pulmonary vascular tree.
mesh_terms: D000328:Adult; D000368:Aged; D000770:Anesthesia, Endotracheal; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D007431:Intraoperative Complications / Q000209:etiology; D007432:Intraoperative Period; D008170:Lung Compliance; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000097:blood; D012119:Respiration; D012126:Respiratory Dead Space
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen