[Differences in the distribution of class I and II antigens of the major histocompatibility complex on the surface of cultured epithelial cells of the mouse thyroid].
From day 9 to 15 of Thyroid Epithelial Cell (TEC) culture the expression of MHC antigens (K, D and Ia) was studied. Methods used for antigen detection included direct cytotoxicity in the presence of rabbit complement and electron microscopy using goat anti-mouse peroxidase-labeled Fab fragments. Results obtained showed that the K and D end-coded MHC antigens (class I) are exclusively expressed on the apical cell surface of TEC while Ia antigens (class II) are only found on the basal part of the cell.
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D002478:Cells, Cultured; D004848:Epithelium / Q000276:immunology; D008285:Major Histocompatibility Complex; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D013961:Thyroid Gland / Q000276:immunology*
D000954:Antigens, Surface
Différences de répartition des antigènes de classe I et II du complexe majeur d'histocompatibilité (CMH) à la surface des cellules épithéliales de thyroïde (CET) murines en culture.