Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II.
D000470:Alkaloids / Q000494:pharmacology*; D000818:Animals; D003600:Cytosol / Q000201:enzymology; D004822:Epididymis / Q000201:enzymology; D006023:Glycoproteins / Q000096:biosynthesis*; D006056:Golgi Apparatus / Q000201:enzymology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D008361:Mannosidases / Q000037:antagonists & inhibitors*; D009928:Organ Specificity; D051381:Rats; D011919:Rats, Inbred Strains; D013379:Substrate Specificity; D017026:Swainsonine
D000470:Alkaloids; D006023:Glycoproteins; D008361:Mannosidases; D017026:Swainsonine