[Effect of cholinomimetics on the rate of hypothermia development].
The rate of hypothermia development was studied in different stages--mild, medium and deep--corresponding with rectal temperatures of 33, 26 and 19 degrees C. This rate significantly decreases in mild hypothermia induced by nicotine (4 mg/kg), in medium hypothermia induced by nicotine and pilocarpine (25 mg/kg), and methacin (20 mg/kg) combined with arecoline (20 mg/kg), in deep hypothermia induced by methacin coupled with arecoline, and significantly rises in deep hypothermia induced by methacin (20 mg/kg) combined with proserin (0.45 mg/kg).
D000818:Animals; D001115:Arecoline / Q000008:administration & dosage; D005731:Ganglionic Stimulants / Q000494:pharmacology; D007036:Hypothermia, Induced; D008297:Male; D009388:Neostigmine / Q000008:administration & dosage; D009538:Nicotine / Q000494:pharmacology; D010115:Oxyphenonium / Q000008:administration & dosage; D010277:Parasympathomimetics / Q000494:pharmacology*; D010862:Pilocarpine / Q000494:pharmacology; D051381:Rats
D005731:Ganglionic Stimulants; D010277:Parasympathomimetics; D010862:Pilocarpine; D009388:Neostigmine; D001115:Arecoline; D009538:Nicotine; D010115:Oxyphenonium
Vliianie kholinomimetikov na skorost' razvitiia gipotermii.