IgG subclasses in rhesus-D immunization. Effects of weekly small volume plasmapheresis.
The IgG subclass composition was determined of the anti-D antibodies present in the serum of 22 women who had a history of severe rhesus-D immunization and who weekly underwent small volume plasmapheresis during their current pregnancy. There was no correlation between the subclass patterns of IgG anti-D antibodies and the degree of illness of the child; the good clinical results obtained with the small volume plasmapheresis could not be explained by a consistent change in the anti-D IgG subclass composition.
D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D004899:Erythroblastosis, Fetal / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000145:classification*; D010956:Plasmapheresis; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G; D012204:Rh-Hr Blood-Group System