title: Effect of various analgesics and lubricants on isolation of Chlamydia trachomatis and Neisseria gonorrhoeae.
abstract: Five preparations used as analgesics or lubricants in surgical, obstetrical, gynecological, and investigative procedures were tested for their effect on the isolation of Chlamydia trachomatis. Three lignocaine preparations and a lubricating jelly containing 2% phenol were inhibitory to chlamydiae. In contrast, K-Y lubricating jelly was relatively nontoxic to chlamydiae. Since K-Y jelly also had only slight toxic activity against gonococci, it is recommended for the lubrication of instruments which need to be used for the efficient isolation of these microorganisms.
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D002692:Chlamydia trachomatis / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D008153:Lubrication; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000700:Analgesics