Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies.
OKT4, a murine monoclonal antibody, was previously shown to react with inducer/helper T cells in man. We now report the absence of this reactivity in 2 subjects of African ancestry and the production of 4 new monoclonal antibodies (OKT4A-D) that detect distinct antigens on human inducer/helper T cells.
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000235:genetics / Q000276:immunology*; D000911:Antibodies, Monoclonal; D006801:Humans; D008297:Male; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology*
D000906:Antibodies; D000911:Antibodies, Monoclonal