title: Role of DNA repair genes and an R plasmid in conferring cryoresistance on Pseudomonas aeruginosa.
abstract: The resistance of Pseudomonas aeruginosa wild-type, uvr, pol and rec strains to ultraviolet (u.v.) light, X-rays and freezing and thawing was determined. An R plasmid, pPL1, which increased resistance of the wild-type uvr, and pol but not rec strains to u.v. light, increased the resistance of only rec and pol mutants to X-rays and freezing and thawing. These findings reinforce the idea of DNA as a target in the organism for freeze-thaw stress and suggest that freeze-thaw-induced DNA damage might be similar to that produced by X-rays but different from that produced by u.v. light.
mesh_terms: D004260:DNA Repair; D005615:Freezing; D009154:Mutation; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000528:radiation effects; D011815:R Factors; D011995:Recombination, Genetic; D014466:Ultraviolet Rays