Prolactin secretion in anorexia nervosa.
Twenty-nine anorectic female patients were subdivided in three groups: group I when primary amenorrhoea; group II when secondary amenorrhoea together with a weight (for their height) equal or above the 10th percentile of the ratio of total water over body weight (TW/B Wt); group III when secondary amenorrhoea was associated with a weight below this 10th percentile. Despite very low mean oestradiol levels (respectively 22, 36 and 32 pg/ml), prolactin secretion remained normal both in basal conditions as well as after 200 micrograms TRH iv. For group III patients, a delay in the peak prolactin response to TRH was observed but it was not statistically significant.
D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000503:physiopathology; D000856:Anorexia Nervosa / Q000503:physiopathology*; D001835:Body Weight; D004958:Estradiol / Q000502:physiology; D005260:Female; D006801:Humans; D011388:Prolactin / Q000378:metabolism* / Q000502:physiology; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology
D004958:Estradiol; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin