Use of simple tasks to test for impairment of complex skills by a sedative.
Examination of the effect of three doses of pentobarbital on the comparative performance of a complex psychomotor task with two simple neuromotor tasks, i. e., standing steady and pendulum eye tracking, revealed a high correlation. These simple tasks could be used as measures of intoxication since they do not require extensive training. Examination of the complex task impairment blood level ratio revealed that impairment relative to blood level was much greater in the absorption phase. This changing ratio underscores the point that blood levels alone are not an adequate estimate of intoxication.
D000328:Adult; D004305:Dose-Response Relationship, Drug; D005133:Eye Movements / Q000187:drug effects*; D006801:Humans; D009068:Movement / Q000187:drug effects*; D010424:Pentobarbital / Q000097:blood* / Q000494:pharmacology; D013997:Time Factors; D014796:Visual Perception / Q000187:drug effects*
D010424:Pentobarbital