Bacillus cereus endocarditis involving a prosthetic valve.
A rare case of "late onset' endocarditis due to Bacillus cereus occurred in a 55-year-old man who had a Carpentier-Edwards heterograft valve. Combination therapy with gentamicin and clindamycin was administered as suggested by testing of minimal bactericidal concentrations for these antibiotics. Valve replacement was necessary because of a paravalvular leak. There was no recurrence after six weeks of therapy.
D001021:Aortic Valve / Q000601:surgery; D001409:Bacillus cereus / Q000472:pathogenicity*; D001705:Bioprosthesis / Q000009:adverse effects*; D002981:Clindamycin / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005839:Gentamicins / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation
D005839:Gentamicins; D002981:Clindamycin