Characterization of cysteine-containing phosphoproteins from human submandibular-sublingual saliva.
Members of a family of acidic proteins taken from human submandibular-sublingual saliva were designated cysteine-containing phosphoproteins, since they could be distinguished from other salivary phosphoproteins by the presence of half-cystine. These molecules consisted of a single peptide chain of approximately 14,000 daltons. Their isoelectric points ranged from 4.3 to 5.9. Two groups (C2 and C3) were O-phosphorylated. Their charge heterogeneity was apparently due to variations in content of phosphate and acidic and basic amino acids.
D000818:Animals; D003545:Cysteine / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D005779:Immunodiffusion; D007123:Immunoelectrophoresis, Two-Dimensional; D007525:Isoelectric Focusing; D007526:Isoelectric Point; D008970:Molecular Weight; D010750:Phosphoproteins / Q000032:analysis*; D011817:Rabbits; D012471:Salivary Proteins and Peptides / Q000032:analysis*
D010750:Phosphoproteins; D012471:Salivary Proteins and Peptides; D003545:Cysteine