[Ultrastructural localization of estradiol and moxestrol in the gonadotropic cells of rat by immunocytology after cryo-ultramicrotomy: evidence for hormonal specificity (author's transl)].
Estradiol (E2) was specifically localized by immunocytochemistry in the cytoplasm and in the nucleus of the gonadotropic cells. The immunocytochemical reaction was not observed after injection of moxestrol, but it was not modified by injection of testosterone, progesterone, or dexamethasone. These data suggest that E2 might be bound to a high-affinity binding-site which could also have a hormonal specificity.
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D004958:Estradiol / Q000378:metabolism*; D045166:Estradiol Congeners / Q000378:metabolism; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives* / Q000378:metabolism; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D005629:Frozen Sections; D006651:Histocytochemistry; D007158:Immunologic Techniques; D007986:Luteinizing Hormone / Q000378:metabolism; D008854:Microscopy, Electron; D010902:Pituitary Gland / Q000378:metabolism / Q000648:ultrastructure*; D051381:Rats
D045166:Estradiol Congeners; D004997:Ethinyl Estradiol; D004958:Estradiol; C011310:moxestrol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Localisation ultrastructurale de l'oestradiol et du moxestrol dans les cellules gonadotropes du rat par immunocytologie après cryo-ultramicrotomie: caractérisation de la spécificité hormonale.