Alfathesin and enflurane: synergistic central nervous system excitation?
This case report describes signs of central nervous system excitation occurring after administration of alfathesin and enflurane in doses lower than those previously associated with this type of phenomena (alfathesin 36 microlitres/kilogram, enflurane two volumes per cent). This suggests that these drugs may interact to increase the probability of seizure-like activity.
D000328:Adult; D000530:Alfaxalone Alfadolone Mixture / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects*; D004357:Drug Synergism; D004737:Enflurane / Q000009:adverse effects*; D004831:Epilepsies, Myoclonic / Q000139:chemically induced; D006801:Humans; D008297:Male
D000530:Alfaxalone Alfadolone Mixture; D004737:Enflurane