title: The effect of inhibitors on the radical formation in aqueous solutions of ascorbic acid.
abstract: The rate of free radical formation in aqueous solutions of ascorbic acid in the presence of chelating agents was measured by the ESR-stopped-flow method. Addition of ethylenediamine tetraacetate and trimetaphosphoric acid to the ascorbic acid-oxygen system results in only a minimal change in the rate of ascorbate free radical formation compared to that in absence of inhibitors. Evidence suggests that radical formation arises via secondary reactions involving products.
mesh_terms: D001205:Ascorbic Acid; D002614:Chelating Agents / Q000494:pharmacology*; D004492:Edetic Acid / Q000494:pharmacology; D005609:Free Radicals; D011122:Polyphosphates / Q000494:pharmacology; D012996:Solutions
chemical_list: D002614:Chelating Agents; D005609:Free Radicals; D011122:Polyphosphates; D012996:Solutions; D004492:Edetic Acid; C009293:trimetaphosphoric acid; D001205:Ascorbic Acid