title: [Metabolic effects of diuretics (author's transl)].
abstract: Thiazide diuretics and loop-diuretics, often used for treatment of hypertension, interfere with various metabolic reactions: An increase of uric acid in plasma is a regular finding, but gout will not be caused, an elevation of plasma lipoproteins has been observed but did not proceed to pathological values, in a number of patients blood glucose has been raised but without producing diabetes mellitus. In general, these metabolic interference are of minor pathological significance. Special treatment for these side-effects are needed in a few cases only. The indicated use of thiazide diuretics should not be disregarded because of their effects on regulatory mechanisms of metabolism.
mesh_terms: D001581:Benzothiadiazines; D001786:Blood Glucose / Q000378:metabolism; D004232:Diuretics / Q000627:therapeutic use*; D004734:Energy Metabolism / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D008055:Lipids / Q000097:blood; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use; D014527:Uric Acid / Q000097:blood
chemical_list: D001581:Benzothiadiazines; D001786:Blood Glucose; D004232:Diuretics; D008055:Lipids; D049993:Sodium Chloride Symporter Inhibitors; D014527:Uric Acid
vernacular_title: Stoffwechselstörungen durch Diuretika.