Binding and internalization of 3H-epinephrine in Tetrahymena.
Exposure of Tetrahymena to exogenous epinephrine is followed by appearance of the hormone in the cell membrane, intracytoplasmic vacuoles and nucleus. The intra-nuclear localization is always heterochromatic. Only a minor proportion of the applied epinephrine dose gains access to the nucleus, while the bulk of it attaches to the membrane.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism*; D009685:Nuclear Envelope; D013769:Tetrahymena pyriformis / Q000378:metabolism*; D014617:Vacuoles / Q000378:metabolism
D004837:Epinephrine