[Evaluation of the bactericidal activity of chiral alkylammonium salts derived from N-benzoyl-amino acids with Escherichia coli and Bacillus cereus. I. -- Evaluation of the antibacterial activity (author's transl)].
Long-chained alkylammonium salts (C12 and C16) obtained from chiral N-benzoyl-amino acids were tested against Escherichia coli and Bacillus cereus, to evaluate their antibacterial efficacy. The bactericidal activity (MBC) determined by the membrane filtration technique and the bacteriostatic activity values suggested anionic group participation. The participation of the anion moiety, depended on nature and configuration of the amino acid. Stereoselective interactions appeared between bacteria and the cationic surfactants tested.
D000596:Amino Acids / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D001409:Bacillus cereus / Q000187:drug effects*; D003470:Culture Media; D004926:Escherichia coli / Q000187:drug effects*; D008968:Molecular Conformation; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D014462:Ultrafiltration
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D003470:Culture Media; D000644:Quaternary Ammonium Compounds
Etude de l'activité bactéricide et bactériostatique de sels d'alkylamines chiraux dérivés d'acides aminés N-benzoylés sur Escherichia coli et Bacillus cereus. 1. -- Activité antibactérienne de sels d'alkylamines dérivés d'acides aminés.