[Biochemistry of antibody production (author's transl)].
A review is given about some biochemical problems in the biosynthesis of immunoglobulins. The following problems are discussed: the specialty of the antibody biosynthesis in comparison to the production of other proteins, antigen binding by lymphocyte receptors, the process of the synthesis of H- and L-chains, the formation of immunoglobulin molecules and their secretion, primary and the secondary immune responses and their regulation, theories of antibodies formation and the problem of the origin of the high number of v genes.
D000818:Animals; D000917:Antibody Formation; D002999:Clone Cells; D005802:Genes, MHC Class II; D006801:Humans; D007114:Immunization; D007143:Immunoglobulin Heavy Chains / Q000096:biosynthesis; D007147:Immunoglobulin Light Chains / Q000096:biosynthesis; D007136:Immunoglobulins / Q000096:biosynthesis*; D007156:Immunologic Memory; D007700:Kinetics; D008214:Lymphocytes / Q000276:immunology*; D008954:Models, Biological; D012333:RNA, Messenger / Q000378:metabolism; D011948:Receptors, Antigen, T-Cell / Q000378:metabolism
D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains; D007136:Immunoglobulins; D012333:RNA, Messenger; D011948:Receptors, Antigen, T-Cell
Biochemie der Antikörperbildung.