title: Depression: diagnosis and treatment with tricyclic antidepressants.
abstract: Recognition of depression as a psychobiologic disorder, its division into categories more descriptive than "endogenous" and "reactive," and use of certain laboratory tests in suspected major (primary) depression have led to increased accuracy of diagnosis. An episode of major depression now can be readily identified by conformance to descriptive criteria, can be confirmed by results of neurophysiologic testing, and can be treated with a tricyclic antidepressant and psychotherapy.
mesh_terms: D000367:Age Factors; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*; D044383:Black People; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy; D003907:Dexamethasone; D006331:Heart Diseases / Q000139:chemically induced; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007099:Imipramine / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use; D009661:Nortriptyline / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use; D011613:Psychotherapy; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
chemical_list: D000929:Antidepressive Agents, Tricyclic; D013973:Thyrotropin-Releasing Hormone; D003907:Dexamethasone; D013972:Thyrotropin; D009661:Nortriptyline; D007099:Imipramine