Metabolism of 2,4',5-trichlorobiphenyl by the mercapturic acid pathway.
Carbon-14-labeled 2,4',5-trichlorobiphenyl was found to be metabolized by the mercapturic acid pathway to metabolites that are excreted in bile. About 57 percent of the carbon-14 was excreted in the bile; 30 to 35 percent was present as mercapturic acid pathway metabolites. Mercapturic acid was also isolated from the urine (0.3 percent of the dose).
D000111:Acetylcysteine / Q000378:metabolism*; D000818:Animals; D001646:Bile / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004064:Digestive System / Q000032:analysis; D005243:Feces / Q000032:analysis; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000032:analysis; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000378:metabolism* / Q000652:urine; D051381:Rats
C015550:2,4',5-trichlorobiphenyl; D011078:Polychlorinated Biphenyls; D000111:Acetylcysteine