title: Developmental stages of genome elimination resulting in transmission ratio distortion of the T-007 male recombination (MR) chromosome of Drosophila melanogaster.
abstract: T-007 is a Male Recombination (MR) second chromosome that induces transmission ratio distortion (at its own expense) when heterozygous with many laboratory marker chromosomes. The developmental timing of elimination of T-007 chromosomes has been investigated. About 21% of the T-007 chromosomes expected to be recovered among the progeny of heterozygous T-007 males are lost at some point between fertilization and eclosion (representing 29% of the total distortion observed in young males). Another 52% of the expected number of T-007 chromosomes are lost as a result of spermatid abortion during spermiogenesis (representing 71% of the total distortion). Abnormalities in both the number of spermatids per bundle and the structure of spermatid tails are seen at the earliest stages of spermiogenesis in T-007 males.
mesh_terms: D000818:Animals; D002872:Chromosome Deletion; D004331:Drosophila melanogaster / Q000235:genetics*; D005306:Fertilization; D005838:Genotype; D006579:Heterozygote; D008297:Male; D011995:Recombination, Genetic; D013091:Spermatogenesis