[Radioautographic study of protein synthesis in the neurons of the epileptogenic mirror focus in the rat brain. I. The stage of the occurrence of steady convulsive activity and the anterior parietal area of the cortex].
Epileptogenic mirror focus was produced in the left parietalis area of rat's brain by cobalt implantation into the controlateral hemisphere. A synthesis of protein was measured autoradiographically in layers III and V neurons of the parietalis anterior area, the lateralis thalamus nucleus of epileptogenic mirror focus on day 14 after cobalt implantation. The incorporation of L-proline-5-3H was found by the increase by 41, 31 and 6% in layer V neurons, layer III neurons and thalamus neurons, resp. Some disturbance of correlation was found between protein synthesis and its expenditure in neurons of the epileptogenic mirror focus. The disturbance was most pronounced in layer V and thalamus neurons.
D000818:Animals; D001345:Autoradiography; D004828:Epilepsies, Partial / Q000378:metabolism*; D008297:Male; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000378:metabolism*; D010296:Parietal Lobe / Q000378:metabolism*; D011392:Proline / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000378:metabolism; D013787:Thalamic Nuclei / Q000378:metabolism; D013997:Time Factors
D009419:Nerve Tissue Proteins; D011392:Proline
Radioavtograficheskoe issledovanie sinteza belka v neĭronakh zerkal'nogo épileptogennogo ochaga mozga krysy. I. Stadiia poiavleniia ustoĭchivoĭ sudorozhnoĭ aktivnosti, perednetemennaia oblast' kory.