Molecular cloning and preliminary characterization of a Drosophila melanogaster gene from a region adjacent to the centromeric beta-heterochromatin.
Using recombinant DNA technology we have isolated a 4.4 kb DNA fragment from Drosophila melanogaster which can be localized by in situ hybridization to the region 80C on the left arm of chromosome III. This DNA fragment codes for a 1.4 kb long poly(A)-containing RNA which comprises about 0.6% of the mass of cytoplasmic poly(A) RNA in Kc cells and Oregon R Embryos. This RNA codes for a 26,000 MW protein of still unknown function.
D000818:Animals; D002503:Centromere; D002875:Chromosomes; D003001:Cloning, Molecular; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D006570:Heterochromatin / Q000648:ultrastructure; D008970:Molecular Weight; D011061:Poly A; D012333:RNA, Messenger / Q000235:genetics*
D006570:Heterochromatin; D012333:RNA, Messenger; D011061:Poly A