Use of a gold compound for the treatment of pemphigus foliaceus in a foal.
A 4-month-old foal was examined because of generalized exfoliative dermatitis, with thick scales, extensive crusting, and oozing of serum. A diagnosis of pemphigus foliaceus was made by histologic and immunopathologic examinations of skin biopsy specimens. The foal was treated with a gold compound, aurothioglucose (1 mg/kg once weekly for 14 weeks). For the initial 5 weeks, high-dose glucocorticoid treatments also was used. The skin disorder resolved entirely after 12 weeks of treatment.
D000818:Animals; D006051:Aurothioglucose / Q000378:metabolism / Q000627:therapeutic use*; D006046:Gold / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy* / Q000473:pathology; D006736:Horses; D008297:Male; D010392:Pemphigus / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
D006051:Aurothioglucose; D006046:Gold