Acquired pure red-cell aplasia associated with an increase of T cells bearing receptors for the Fc of IgG.
A case of steroid-resistant acquired pure red-cell aplasia associated with a relative and absolute increase of TG cells is described. Removal of T cells enhanced erythroid colony and burst formation in vitro, and it is suggested that TG cells may be implicated in the pathogenesis of this case of acquired pure red-cell aplasia.
D000741:Anemia, Aplastic / Q000276:immunology*; D001854:Bone Marrow Cells; D003114:Colony-Forming Units Assay; D006801:Humans; D007074:Immunoglobulin G; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D011961:Receptors, Fc; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000201:enzymology / Q000276:immunology*
D007074:Immunoglobulin G; D011961:Receptors, Fc