Virologic control of monkeys used for the production of poliomyelitis virus vaccine.
Wild-caught or captive-bred cynomolgus monkeys (Macaca fascicularis) used at the National Institute of Public Health for the production of inactivated poliomyelitis virus vaccine are extensively controlled for the presence of antiviral antibodies in their sera. With relatively simple methods of segregation and hygienic measures it seems possible to keep the animals free of infections with certain viruses including Herpesvirus simiae and foamy viruses, which is of obvious importance for Public Health and for vaccine production.
D000818:Animals; D000882:Haplorhini; D008251:Macaca / Q000276:immunology*; D008252:Macaca fascicularis / Q000276:immunology*; D009426:Netherlands; D011054:Poliovirus Vaccine, Inactivated / Q000592:standards*; D014765:Viral Vaccines / Q000592:standards*
D011054:Poliovirus Vaccine, Inactivated; D014765:Viral Vaccines