[The effect of (+)-cyanidanol-3 on toxic fatty infiltration of liver parenchyma (author's transl)].
Polychlorinated biphenyls, pentachlorophenol, d-galactosamine or alcohol are well known substances which produce toxic liver damage in animal experiments. Of special significance is the toxic fatty infiltration in the live parenchyma of these models. The effects following (+)-Cyanidanol-3 (Catergen)--application after liver damage was studied by qualitative and quantitative electron microscopy. (+)-Cyanidanol-3 reduces the volume density of intracytoplasmatic fat following intoxication significantly to normal values.
D000818:Animals; D001578:Benzopyrans / Q000494:pharmacology*; D002392:Catechin / Q000494:pharmacology*; D000431:Ethanol / Q000037:antagonists & inhibitors; D005234:Fatty Liver / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D005688:Galactosamine / Q000037:antagonists & inhibitors; D008297:Male; D010416:Pentachlorophenol / Q000037:antagonists & inhibitors; D011078:Polychlorinated Biphenyls / Q000037:antagonists & inhibitors; D051381:Rats
D001578:Benzopyrans; D000431:Ethanol; D005688:Galactosamine; D002392:Catechin; D010416:Pentachlorophenol; D011078:Polychlorinated Biphenyls
Der Einfluss von (+)-Cyanidanol-3 auf die toxische Verfettung des Leberparenchyms. Eine tierexperimentell feinstrukturell-morphometrische untersudhung.