title: Sequence homologies in the 5' regions of four Drosophila heat-shock genes.
abstract: We report nucleotide sequences of the regions surrounding the 5' ends of the genes for Drosophila melanogaster heat-shock proteins hsp83, hsp68, and hsp26, located at chromosome positions 63BC, 95D, and 67B, respectively. As in other eukaryotic genes, the sequence T-A-T-A-A-A-A-T occurs about 30 nucleotides upstream from the sites of mRNA initiation. Three additional sequence homologies and a dyad symmetry were noted at approximately corresponding locations in the three genes and in the gene for another heat-shock protein, hsp70. We also found an intron near the 5' end of the hsp83 gene, with sequences at its boundaries typical of splice sites found in other organisms.
mesh_terms: D000818:Animals; D001483:Base Sequence; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D006360:Heat-Shock Proteins; D008970:Molecular Weight; D011506:Proteins / Q000235:genetics*; D012333:RNA, Messenger / Q000096:biosynthesis; D014158:Transcription, Genetic
chemical_list: D006360:Heat-Shock Proteins; D011506:Proteins; D012333:RNA, Messenger