title: Genital ulcers in Kenya. Clinical and laboratory study.
abstract: Of 97 patients with genital ulcers attending a special treatment clinic in Nairobi, Kenya, 60 harboured Haemophilus ducreyi, four herpes simplex virus, and five Neisseria gonorrhoeae. Eleven patients had serological evidence of syphilis; of these one case was confirmed by darkfield microscopy. In the remaining cases no aetiological agent was identified. An enriched chocolate agar with vancomycin and serum was a useful medium for primary isolation of H ducreyi. Tetracycline was generally ineffective in the treatment of ulcers, but sulfadimidine was successful in almost 80% of cases.
mesh_terms: D000328:Adult; D002602:Chancroid / Q000188:drug therapy; D005260:Female; D005832:Genital Diseases, Male / Q000382:microbiology*; D006191:Haemophilus ducreyi / Q000302:isolation & purification; D006801:Humans; D007630:Kenya; D008297:Male; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D013418:Sulfamethazine / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use; D014456:Ulcer / Q000382:microbiology*
chemical_list: D013418:Sulfamethazine; D013752:Tetracycline