[Aspartate and alanine aminotransferase activity in the liver and blood serum of protein-deficient rats receiving parenteral nitrogen nutrition].
The activity of aspartate and alanine aminotranspherase in the liver and blood serum was determined under parenteral nitrogen nutrition against a background of protein deficiency and protein inanition. The activity of these enzymes in the rat liver under conditions of protein deficiency and inanition is practically the same. The intraperitoneal administration of aminosol and amikin against a background of 10- and 20-day protein deficiency increases the activity of the enzymes under study in the liver. With protein deficiency and inanition the aspartate aminotranspherase activity in the liver under conditions of amikin per os feeding in the composition of protein-free semisynthetic food is considerably lower than under parenteral administration of this preparation respective dose. Under given condition of the experiment the alanine aminotranspherase activity in the liver is, vice versa, higher under per os feeding than under parenteral administration of amikin. It is also shown that administration of the parenteral nitrogen nutrition preparations containing only free amino acids (amikin) or a mixture of free amino acids and low-molecular peptides (aminosol) has a unidirected effect on reamination reactions adaptability in the liver.
D000410:Alanine Transaminase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008297:Male; D009584:Nitrogen; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total; D011488:Protein Deficiency / Q000201:enzymology*; D051381:Rats
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D009584:Nitrogen
Aspartat- i alaninaminotransferaznaia aktivnost' v pecheni i syvorotke krovi krys pri parenteral'nom azotistom pitanii na fone belkovogo golodaniia.