title: Cardiac effects of antidepressants.
abstract: Cardiac effects of tricyclics and tetracyclics, while common, are most frequently benign and well-tolerated. For older patients with underlying disease, however, closer clinical monitoring is needed. The most common effect of MAOIs in healthy adults taking normal dosages is orthostatic hypotension. The most serious reaction to MAOIs is hypertensive crisis, which may be fatal.
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000494:pharmacology*; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy; D004347:Drug Interactions; D006321:Heart / Q000187:drug effects*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000139:chemically induced; D008094:Lithium / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016651:Lithium Carbonate; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D008996:Monoamine Oxidase Inhibitors; D016651:Lithium Carbonate; D008094:Lithium