Inhibition of aflatoxin production by selected insecticides.
The insecticide naled completed inhibition production of aflatoxins B1, B2, G1, and G2 by and growth of Aspergillus parasiticus at a 100-ppm (100 microgram/ml) concentration. The insecticides dichlorvos, Landrin, pyrethrum, Sevin, malathion, and Diazinon significantly (P = 0.05) inhibited production of aflatoxins at a 100-ppm concentration. However, at a concentration of 10 ppm, significant inhibition in production of aflatoxins was found only with naled, dichlorvos, Sevin, Landrin, and pyrethrum. Dichlorvos, Landrin, Sevin, and naled inhibited growth of A. parasiticus by 28.9 , 18.9, 15.7, and 100%, respectively, at 100 ppm. Stimulation of growth was observed when diazinon was added to cultures. Aflatoxin B1 was most resistant to inhibition by insecticides, followed by G1, G2, and B2, respectively.
D000348:Aflatoxins / Q000096:biosynthesis*; D001230:Aspergillus / Q000187:drug effects / Q000378:metabolism*; D002219:Carbamates / Q000494:pharmacology; D012721:Carbaryl / Q000494:pharmacology; D003976:Diazinon / Q000494:pharmacology; D004006:Dichlorvos / Q000494:pharmacology; D007306:Insecticides / Q000494:pharmacology*; D008294:Malathion / Q000494:pharmacology; D009267:Naled / Q000494:pharmacology
D000348:Aflatoxins; D002219:Carbamates; D007306:Insecticides; D004006:Dichlorvos; D009267:Naled; D012721:Carbaryl; C001519:trimethacarb; D008294:Malathion; D003976:Diazinon