Presence of glutamate decarboxylase in bovine adrenal medullary cells.
Data confirming the presence of GAD in bovine adrenal medullary cells are reported. The subcellular distribution of this enzyme seems to be cytosolic and mitochondrial. The possibility of two GAD, GAD I and GAD II, is discussed. The mitochondrial enzymatic activity has been checked by both the "C-CO2 liberated and the presence of 14C-GABA formed.
D000313:Adrenal Medulla / Q000201:enzymology*; D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D002262:Carboxy-Lyases / Q000032:analysis*; D002417:Cattle / Q000502:physiology*; D003600:Cytosol / Q000201:enzymology; D005968:Glutamate Decarboxylase / Q000032:analysis*; D005971:Glutamates / Q000378:metabolism; D008928:Mitochondria / Q000201:enzymology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D005971:Glutamates; D002245:Carbon Dioxide; D005680:gamma-Aminobutyric Acid; D002262:Carboxy-Lyases; D005968:Glutamate Decarboxylase