title: [Serologic studies of patients with meningococcal nasopharyngitis].
abstract: The results of the serological examination of 156 patients with bacteriologically confirmed meningococcal nasopharyngitis are presented. For control 221 patients with acute respiratory diseases and 345 healthy persons from groups having no registered cases of meningococcal infection were examined. The passive hemagglutination test with serogroup A and C polysaccharides revealed the presence of antibody titers between 1:20 and 1:640 in 67.3% of nasopharyngitis patients and antibody titers not exceeding 1:40 in 11.3-11.6% of persons in the control groups. The time course of antibody formation in nasopharyngitis was similar to that in generalized forms, but response was less pronounced: the maximum response was observed on days 5-10, and the decrease of the antibody level by day 20. In 47 foci of meningococcal infection the etiology of the disease was serologically confirmed on the first day of an epidemiologist's visit to the focus in 62.2% of 162 nasopharyngitis patients and in 36% of patients with acute respiratory diseases.
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis* / Q000096:biosynthesis; D002648:Child; D002675:Child, Preschool; D006386:Hemagglutination Tests; D006801:Humans; D008589:Meningococcal Infections / Q000097:blood* / Q000276:immunology; D009304:Nasopharyngitis / Q000097:blood* / Q000276:immunology; D009345:Neisseria meningitidis / Q000302:isolation & purification; D010612:Pharyngitis / Q000097:blood*; D012703:Serotyping
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Serologicheskie issledovaniia u bol'nykh meningokokkovymi nazofaringitami.