title: Rate of turnover of structural variants in the rDNA gene family of Drosophila melanogaster.
abstract: A high degree of polymorphism for the length and copy number of rDNA spacers, in both the X and Y chromosome clusters, has been found in a wild population of Drosophila melanogaster. The genetic behaviour of rDNA structural variants in separate and mixed populations derived from isofemale lines suggest that they are not subject to strong selection and are stable for over 1,000 generations. The high structural variability suggests an evolutionary rapid process of turnover in the family which could partly explain widespread sequence homogeneity (concerted evolution) of rDNA within a species.
mesh_terms: D000818:Animals; D001483:Base Sequence; D004274:DNA, Recombinant; D004275:DNA, Ribosomal; D004331:Drosophila melanogaster / Q000235:genetics*; D005796:Genes; D014644:Genetic Variation; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D012730:Sex Chromosomes; D014158:Transcription, Genetic
chemical_list: D004274:DNA, Recombinant; D004275:DNA, Ribosomal