[Changes in microorganism sensitivity to antibiotics as affected by divalent metal ions].
Ca+ and Mg+ in nutrient media significantly influence the results of antibiotic sensitivity determination in microorganisms. The data of the study are indicative of a necessity for the media standardization with respect to the content of bivalent metal ions. It is recommended that agar-agar manufactured by the South Sea Factory (tafuinsky) be used for preparation of nutrient media for determination of microbial sensitivity to antibiotics and Hottinger meat pancreatic digest as the nitrogen source providing the content of 120 mg per cent of amine nitrogen in the medium.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002118:Calcium / Q000494:pharmacology*; D002413:Cations, Divalent / Q000494:pharmacology; D003470:Culture Media / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D008274:Magnesium / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D002413:Cations, Divalent; D003470:Culture Media; D008274:Magnesium; D002118:Calcium
Izmenenie chuvstvitel'nosti mikroorganizmov k antibiotikam pod vliianiem ionov dvukhvalentnykh metallov.