Glucose metabolism in the testis of the normal and streptozotocin diabetic rat.
In the present work, the metabolism of [U-14C]glucose was studied in the testicular tissue of normal and streptozotocin diabetic rats. The results show that diabetes alters 14CO2 production and 14C incorporation into lipids from [U-14C]glucose. No differences were found in the [14C]proteins and [14C]nucleic acids between experimental groups. Results are discussed in relation to an insulin deficiency and/or an alteration in the hypothalamic-hypophyseal-gonadal axis.
D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D002250:Carbon Radioisotopes; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D007328:Insulin / Q000172:deficiency; D050356:Lipid Metabolism; D008297:Male; D009696:Nucleic Acids / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013737:Testis / Q000378:metabolism*
D002250:Carbon Radioisotopes; D007328:Insulin; D009696:Nucleic Acids; D011506:Proteins; D002245:Carbon Dioxide; D005947:Glucose