Extensive pharyngeal hemorrhage induced by dipyridamole.
An extensive hemorrhage in the pharynx appeared in association with dipyridamole administration to a diabetic patient. The hemorrhage caused dysphagia and subsided when the drug was discontinued. Coagulation tests were normal except for a decreased platelet aggregation. Platelet factor 3 and the aggregation tests with adenosine diphosphate and epinephrine were abnormal during the hemorrhagic event and returned to normal after discontinuation of the drug.
D002747:Chlorpropamide / Q000627:therapeutic use; D003327:Coronary Disease / Q000188:drug therapy; D003920:Diabetes Mellitus / Q000188:drug therapy; D004176:Dipyridamole / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000139:chemically induced*
D004176:Dipyridamole; D007548:Isosorbide Dinitrate; D002747:Chlorpropamide