title: [Histochemical demonstration of beta-glucuronidase and leucine aminopeptidase in cultivated aortic endothelial cells (author's transl)].
abstract: With the aid of histochemical techniques, the activity of beta-GD, LAP, NADH-D, and LDH of in vitro cultivated calf aortic endothelial cells were compared with the activity of these enzymes in different tumours in vivo. The relative high level of beta-GD, NADH-D, and LDH in the endothelial cells is comparable with the increased activity of these enzymes in invasive growing tumours. The results were discussed in connection with a possible enzymolytic effect during the invasive growth of capillary endothelial cells in course of neovascularization in vivo.
mesh_terms: D000818:Animals; D001011:Aorta / Q000201:enzymology*; D002417:Cattle; D002478:Cells, Cultured; D008058:Dihydrolipoamide Dehydrogenase / Q000378:metabolism; D004727:Endothelium / Q000201:enzymology; D005966:Glucuronidase / Q000378:metabolism*; D006651:Histocytochemistry; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007931:Leucyl Aminopeptidase / Q000378:metabolism*
chemical_list: D007770:L-Lactate Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase; D005966:Glucuronidase; D007931:Leucyl Aminopeptidase
vernacular_title: Zum histochemischen Nachweis von beta-Glucuronidase und Leucinaminopeptidase in kultivierten Gefässendothelzellen.