Effect of reduction of anticonvulsants on wellbeing.
An attempt was made over a period of a year to reduce the number of anticonvulsants used to treat epilepsy in a hospital for the mentally handicapped. At least one drug was withdrawn for each of 20 patients, without loss of seizure control. Effect on wellbeing was assessed by a behavioural scale completed before and after withdrawal, and in the 20 cases of successful withdrawal wellbeing was significantly improved.
D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects; D001519:Behavior / Q000187:drug effects; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D013375:Substance Withdrawal Syndrome
D000927:Anticonvulsants