Hyperosmotic solutions and hearing Meniere's disease.
Hearing was studied in nineteen patients with Meniere's disease before and after administration of three different hyperosmolar solutions-glycerol, ethanol, and Mannitol. Ethanol and Mannitol were found to be much less effective than glycerol in producing hearing gain. Alternative mechanisms underlying the observed differences are discussed.
D004359:Drug Therapy, Combination; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D005990:Glycerol / Q000627:therapeutic use*; D006309:Hearing / Q000187:drug effects; D006801:Humans; D008297:Male; D008353:Mannitol / Q000627:therapeutic use*; D008575:Meniere Disease / Q000188:drug therapy*; D008875:Middle Aged; D009994:Osmolar Concentration
D000431:Ethanol; D008353:Mannitol; D005990:Glycerol