[Immunochemical characteristics of plant pollen allergoid].
Allergen from ragweed pollen was treated with formaldehyde to obtain allergoid. The preparation obtained loses to a significant extent its ability to react not only with allergic antibodies (reagins) of the patients but also with precipitins of sera from rabbits hyperimmunized with allergen. Immunoelectrophoresis in agarose allowed a conclusion that formaldehyde blocks up to 4--5 antigens possessing a higher positive electrophoretic charge. Electrophoresis in polyacrylamide gel has shown that concurrently there occur stabilization and enlargement of protein molecules.
D000485:Allergens / Q000276:immunology* / Q000302:isolation & purification; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D011058:Pollen / Q000276:immunology*; D011817:Rabbits / Q000276:immunology
D000485:Allergens
Immunokhimicheskaia kharakteristika allergoida iz rastitel'noĭ pyl'tsy.