[Study of three biocides (dimethoate, parathion ethyl and zineb) on female rat neuro endocrinological balance (author's transl)].
The authors studied the neuro endocrinological effects of three pesticides. Two of them were organophosphorus compounds (ethyl parathion and dimethoate) and one was a carbamate (zineb). Mature female rats have been orally administered these compounds for 16 days at respectively 1/25, 1/10 and 1/10 of the LD50. The parameters recorded are: the gonadotropins, the length of estrous cycle and the weight of the anterior pituitary gland, the ovaries and the uterus. In contradistinction with the organochlorine compounds the organophosphorus did not induce any disturbances in the neuro endocrinological system, whereas the carbamate compound decreased the pituitary gonadotropins.
D000818:Animals; D004117:Dimethoate / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood*; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000187:drug effects*; D010278:Parathion / Q000494:pharmacology*; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013859:Thiocarbamates / Q000494:pharmacology*; D014599:Uterus / Q000187:drug effects*; D015038:Zineb / Q000494:pharmacology*
D013859:Thiocarbamates; D010278:Parathion; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D004117:Dimethoate; D015038:Zineb
Effets de trois biocides: le deméthoate, le parathion éthyl et le zinèbe sur l'équilibre neuro endocrinien du rat femelle.