title: [HLA system and collagen diseases (author's transl)].
abstract: Association of histocompatibility antigen (HLA antigens) with collagen diseases is not a casual event. Even known data, the practical conclusions have a limited usefullness because there is not a definitive correspondence between HLA antigens and rheumatic diseases. With HLA typing is possible to determine risk populations. The pauciarticular type II of juvenile reumatoid arthritis (J.R.A) is associated with HLA-B27 in the 75% of cases. Also, this antigen is associated with ankylosing spondylitis, Reiter's disease, Behçet disease, psoriasic arthritis, reactive arthritis (yersinia, shigella, salmonella). Systemic lupus erythematosus has been described associated with HLA-B8 and HLA-DRw2.
mesh_terms: D000818:Animals; D003095:Collagen Diseases / Q000235:genetics / Q000276:immunology*; D004198:Disease Susceptibility; D005802:Genes, MHC Class II; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006801:Humans; D007111:Immunity, Cellular; D008285:Major Histocompatibility Complex
chemical_list: D006680:HLA Antigens
vernacular_title: Antígenos de histocompatibilidad HLA en las colagenosis.