[Affinity of tritiated S-adenosyl-L-homocysteine for membrane preparations from various parts of rat the rat brain].
The study of tritiated S-adenosyl-L-homocysteine binding in various areas of the Rat brain has shown that the affinity was the same in the different regions whereas the number of binding sites was greater in the hippocampus and in the cerebellum than in the cortex, the corpus striatum, the mesencephalon, the hypothalamus and the brainstem. The phosphatidylethanolamine-N-methylase activity was also greater in the hippocampus and in the cerebellum.
D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000378:metabolism* / Q000648:ultrastructure; D002462:Cell Membrane / Q000378:metabolism; D006710:Homocysteine / Q000031:analogs & derivatives*; D066298:In Vitro Techniques; D007700:Kinetics; D008780:Methyltransferases / Q000378:metabolism; D050918:Phosphatidylethanolamine N-Methyltransferase; D051381:Rats; D012435:S-Adenosylhomocysteine / Q000378:metabolism*; D014316:Tritium
D006710:Homocysteine; D014316:Tritium; D012435:S-Adenosylhomocysteine; D008780:Methyltransferases; D050918:Phosphatidylethanolamine N-Methyltransferase
Affinité la S-adénosyl-L-homocystéine tritée pour des préparations membranaires de différentes parties du cerveau de rat.