Clinical applications of the radioimmunoassay of secretory tuberculoprotein.
A radioimmunoassay that measures a specific secretory tuberculoprotein was used to detect Mycobacterium tuberculosis in 9 of 30 liquid cultures of sputum. The accumulation of immunoreactive material in liquid cultures containing isoniazid was shown to reflect in vitro susceptibility of mycobacteria to the antibiotic effects of the drug.
D001426:Bacterial Proteins / Q000032:analysis*; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000032:analysis* / Q000187:drug effects; D011863:Radioimmunoassay / Q000379:methods; D013183:Sputum / Q000382:microbiology*; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology
D001426:Bacterial Proteins; C030960:tuberculoprotein, Mycobacterium tuberculosis; D007538:Isoniazid