title: beta-Alanine and alpha-L-alanine inhibit the exploratory activity of spontaneously hypertensive rats.
abstract: 1% beta-alanine and alpha-L-alanine, when given for 7 days as the only drinking fluid, inhibited the exploratory activity of adult male spontaneously-hypertensive rats (SHR) but not that of the normotensive Wistar-Kyoto rats (WKR). beta-Alanine decreased the taurine level in the liver of both strains and in the platelets of SHR. alpha-Alanine decreased the taurine level in the liver of WKR and in the platelets of SHR.
mesh_terms: D000409:Alanine / Q000494:pharmacology*; D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D005106:Exploratory Behavior / Q000187:drug effects*; D006321:Heart / Q000187:drug effects; D006973:Hypertension / Q000503:physiopathology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013654:Taurine / Q000378:metabolism; D015091:beta-Alanine / Q000494:pharmacology*
chemical_list: D015091:beta-Alanine; D013654:Taurine; D000409:Alanine