title: [Brucella L-forms, their revertants and initial cultures].
abstract: The transformation of Brucella into a relatively stable bacterial L-form leads to a sharp decrease in virulence and the loss of their capacity for agglutination under the action of commercial brucellosis antiserum. When reverting from the L-form, Brucella cells partially restore their virulence and agglutinability. The pronounced restoration of these properties can be observed in revertants from the L-forms, obtained in vivo. All revertants are less virulent than the initial strains. The transformation into the L-forms is accompanied by a sharp decrease in their electrokinetic mobility, which is indicative of profound transformations of their peripheral structures leading to the exposure of the electrically inert layers of the cell wall.
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D002002:Brucella / Q000472:pathogenicity / Q000502:physiology*; D002003:Brucella abortus / Q000472:pathogenicity / Q000502:physiology; D003470:Culture Media / Q000494:pharmacology; D004594:Electrophysiology; D006168:Guinea Pigs; D007700:Kinetics; D007740:L Forms / Q000472:pathogenicity / Q000502:physiology*; D014774:Virulence
chemical_list: D003470:Culture Media
vernacular_title: Izuchenie L-form brutsell, ikh revertantov i iskhodnykh kul'tur.