title: Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control.
abstract: Mucoid variants of Pseudomonas aeruginosa isolated in vitro or in vivo could be classified into two phenotypic groups based on whether alginate was produced on a chemically defined medium. Mucoid strains yielded lowe recombination frequencies than the non-mucoid parent when used as donors in FP2-mediated plate matings. The mucoid characteristic (muc) was co-inherited by a proportion of recombinants selected for the inheritance of chromosomal markers his-5075+ or cys-5605+. The results of further experiments using either a mucoid recipient or a mucoid donor carrying plasmid R68.45 suggested that the control of alginate production in P. aeruginosa involves at least one chromosomal locus.
mesh_terms: D000464:Alginates / Q000378:metabolism*; D002874:Chromosome Mapping; D008040:Genetic Linkage; D005819:Genetic Markers; D010641:Phenotype; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000378:metabolism; D011995:Recombination, Genetic
chemical_list: D000464:Alginates; D005819:Genetic Markers