Stimulation of sporulation by ppApp in a conditionally asporogenous rifampin-resistant mutant in Bacillus subtilis.
Addition of ppApp to Sterlini-Mandelstam medium stimulates sporulation of a conditionally asporogenous rifampin-resistant mutant of Bacillus subtilis to the same extent as the effect of 4 amino acids. Mutant cells sporulating in the presence of amino acids also produce 2 phosphorylated nucleotides one of which comigrated with ppApp on PEI thin layer chromatogram.
D000225:Adenine / Q000494:pharmacology; D000227:Adenine Nucleotides / Q000494:pharmacology*; D000249:Adenosine Monophosphate / Q000494:pharmacology; D000596:Amino Acids / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects / Q000502:physiology*; D004352:Drug Resistance, Microbial; D007700:Kinetics; D012293:Rifampin / Q000494:pharmacology*; D013171:Spores, Bacterial / Q000187:drug effects / Q000502:physiology
D000227:Adenine Nucleotides; D000596:Amino Acids; C017990:adenosine 3'-diphosphate 5'-diphosphate; D000249:Adenosine Monophosphate; D000225:Adenine; D012293:Rifampin