title: R-wave amplitude and left ventricular volume: changes with nitroglycerine and atrial pacing.
abstract: The relationship between R-wave amplitude and left ventricular volume was examined using two groups of patients, undergoing diagnostic cardiac catheterisation for investigation of chest pain, who had simultaneous R-wave recording and left ventricular angiography. R-wave amplitude was measured in leads 1, 2, 3 and V4-6. Left ventricular volume was altered by nitroglycerine (n = 18) and atrial pacing (n = 13). In both groups, increase or decrease in left ventricular volume was associated with a concomitant change of R-wave amplitude. We conclude that left ventricular volume is an important determinant of surface-recorded R waves with increased amplitude reflecting increased left ventricular volume and vice versa.
mesh_terms: D000792:Angiography; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial; D002306:Cardiac Volume; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006325:Heart Atria; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology; D013909:Thorax
chemical_list: D005996:Nitroglycerin