[Changes in the phospholipid spectrum and activity of certain phosphatide-synthesis enzyme systems in the brain and liver of rats with alloxan diabetes].
The experiments on brain and liver tissues of rats with alloxan diabetes have shown significant changes in the qualitative and quantitative composition of phospholipids. In the test tissues there was a pronounced inhibition of glycerokinase. It is of interest to note that the activity of L-alpha-glycerophosphate dehydrogenase varies in direct and reverse reactions.
D000496:Alloxan; D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology / Q000378:metabolism*; D005260:Female; D005991:Glycerol Kinase / Q000378:metabolism; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D009928:Organ Specificity; D010743:Phospholipids / Q000032:analysis*; D051381:Rats
D010743:Phospholipids; D000496:Alloxan; D005993:Glycerolphosphate Dehydrogenase; D005991:Glycerol Kinase
Izmeneniia fosfolipidnogo spektra i aktivnosti nekotorykh fermentnykh sistem fosfatidogeneza v golovnom mozge i pecheni belykh krys s alloksanovym diabetom.