Localization of gold in biological tissue. A photochemical method for light and electronmicroscopy.
A detailed description is given of a method by which gold can be visualized in frozen, paraffin and Epon sections. Histological sections from animals treated with gold compounds are exposed to UV-light from 30 min to several hours. The reduced, metallic gold is then visualized by means of a photographic developer containing silver lactate. Light- and electronmicroscope photographs showing gold in different organs from rats and mice treated with aurothioglucose, aurothiosulfate and aurothiomalate are presented.
D000818:Animals; D006051:Aurothioglucose / Q000378:metabolism; D006046:Gold / Q000032:analysis* / Q000378:metabolism; D006052:Gold Sodium Thiomalate / Q000378:metabolism; D012971:Gold Sodium Thiosulfate / Q000032:analysis* / Q000378:metabolism; D006651:Histocytochemistry / Q000379:methods*; D051379:Mice; D010777:Photochemistry; D051381:Rats; D012834:Silver; D014018:Tissue Distribution; D014466:Ultraviolet Rays
D006052:Gold Sodium Thiomalate; D006051:Aurothioglucose; D012834:Silver; D006046:Gold; D012971:Gold Sodium Thiosulfate