title: Effect of diflubenzuron and its major degradation products on the growth of Euglena gracilis Z. and incorporation of glycine-U-14C in protein.
abstract: Diflubenzuron (I) and its major degradation products 4-chlorophenyl urea (II), 2,6-difluorobenzoic acid (III) and 4-chloroaniline (IV) were tested for their activity on Euglena gracilis Z. The inhibition on the growth and on the incorporation of glycine-U-14C in the protein of Euglena was measured in the presence of I-IV ranging 10 to 200 ppm. 4-chloroaniline caused a considerable inhibition at every tested level whereas I-III slightly affected only the incorporation. Therefore, it must be inferred that diflubenzuron shows no effect on growth and protein biosynthesis for this nontarget organism.
mesh_terms: D002250:Carbon Radioisotopes; D004132:Diflubenzuron / Q000494:pharmacology*; D005056:Euglena gracilis / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D005998:Glycine / Q000378:metabolism*; D007605:Juvenile Hormones / Q000378:metabolism / Q000494:pharmacology*; D011506:Proteins / Q000378:metabolism*
chemical_list: D002250:Carbon Radioisotopes; D007605:Juvenile Hormones; D011506:Proteins; D004132:Diflubenzuron; D005998:Glycine