title: The effect of sucrose and hexitol--containing chewing gums on plaque acidogenesis in vivo.
abstract: Comparative quantitation of plaque organic acids formed in vivo in the course of chewing sucrose and sorbitol-mannitol containing gums disclosed that the hexitol gum did not generate any additional lactic, formic, butyric, propionic, acetic or pyruvic acid beyond baseline (0 time) values. In contrast, sucrose-containing gum produced significant increases in lactic and butyric acids. Quantitatively, acetic acid was the major acid in all plaque samples; the values were comparable for both gums at all times, suggesting it was mainly generated from endogenous sources.
mesh_terms: D000143:Acids / Q000378:metabolism; D000328:Adult; D002638:Chewing Gum; D003733:Dental Caries Susceptibility; D003773:Dental Plaque / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008353:Mannitol / Q000494:pharmacology*; D013012:Sorbitol / Q000494:pharmacology*; D013395:Sucrose / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000143:Acids; D002638:Chewing Gum; D008353:Mannitol; D013012:Sorbitol; D013395:Sucrose