title: Endocrine mechanisms in the pathogenesis of essential hypertension. III. Special reference on the interrelations between the prostaglandin and kallikrein-kinin systems.
abstract: In the present paper, the involvement of the renal kallikrein-kinin system in the pathogenic mechanism of essential hypertension is discussed in the larger framework of the complex hormonal actions of prostaglandins (PGs), catecholamines, renin and angiotensins in the long-term control of arterial blood pressure and sodium metabolism. An attempt is also made to emphasize the role of the cerebral renin-angiotensin system in this pathogenic mechanism. To better understand the problems raised in this paper, the concomitant consultation of two previously published papers [88], [89] is recommended.
mesh_terms: D015070:18-Hydroxydesoxycorticosterone / Q000378:metabolism; D000804:Angiotensin II / Q000378:metabolism; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D006973:Hypertension / Q000503:physiopathology*; D007610:Kallikreins / Q000378:metabolism* / Q000652:urine; D007705:Kinins / Q000378:metabolism*; D011453:Prostaglandins / Q000378:metabolism*; D051381:Rats; D012083:Renin / Q000378:metabolism; D012504:Saralasin / Q000494:pharmacology; D012964:Sodium / Q000378:metabolism; D014867:Water / Q000378:metabolism
chemical_list: D015070:18-Hydroxydesoxycorticosterone; D007705:Kinins; D011453:Prostaglandins; D014867:Water; D000804:Angiotensin II; D012964:Sodium; D007610:Kallikreins; D012083:Renin; D012504:Saralasin