A possible mechanism of induction of insect lectin.
Studies were made using antibody against a lectin induced in the hemolymph of Sarcophaga peregrina larvae on injury. The results suggested that the alpha subunit (Mr = 32,000) of the lectin is normally present in the hemolymph. On injury of the body wall, part of the alpha subunit seems to be converted to the beta subunit (Mr = 30,000), probably by partial proteolysis with a protease activated in response to the injury. As a result, an active lectin with the structure alpha 4 beta 2 is formed.
D000818:Animals; D000906:Antibodies; D004175:Diptera / Q000378:metabolism*; D006458:Hemolymph / Q000378:metabolism*; D005779:Immunodiffusion; D007814:Larva / Q000378:metabolism; D037102:Lectins / Q000302:isolation & purification; D046911:Macromolecular Substances; D008970:Molecular Weight; D010446:Peptide Fragments / Q000032:analysis
D000906:Antibodies; D037102:Lectins; D046911:Macromolecular Substances; D010446:Peptide Fragments