title: [Serum thyrocalcitonin and parathyroid hormone content in children with diffuse toxic goiter and hypothyroidism].
abstract: Radioimmunoassay was used to study the blood thyrocalcitonin (TCT) and parathyroid hormone (PH) content in children with diffuse toxic goitre and hypothyrosis. The blood plasma TCT content was determined in 20 children with thyrotoxicosis and in 28 subjects with hypothyrosis. PH content was examined correspondingly in 18 and 20 patients. It was concluded that the blood TCT concentration is not significantly changed in children suffering from diffuse toxic goitre and hypothyrosis. PH content decreases in patients with thyrotoxicosis. Wide variability of PH individual values is peculiar to hyperthyrosis. TCT and PH have no essential significance in the pathogenesis of bone injuries and mineral metabolism changes in thyroid diseases of children.
mesh_terms: D000293:Adolescent; D002116:Calcitonin / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006111:Graves Disease / Q000097:blood*; D006801:Humans; D007011:Hypoparathyroidism / Q000209:etiology; D007037:Hypothyroidism / Q000097:blood*; D007223:Infant; D010281:Parathyroid Hormone / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000032:analysis
chemical_list: D010281:Parathyroid Hormone; D013975:Thyroxine-Binding Proteins; D002116:Calcitonin; D013974:Thyroxine
vernacular_title: Soderzhanie tireokal'tsitonina i paratireoidnogo gormona v krovi u deteĭ s diffuznym toksicheskim zobom i gipotireozom.