Double diffusion analysis of antigens released from Plasmodium knowlesi in vitro.
Two parasite-derived antigens (designated band 1 and band 2) were identified upon double-diffusion analysis of culture medium from reinvading culture of P. knowlesi. Band 1 antigen showed characteristics with the R-antigens of P. falciparum while the other was similar to the P. falciparum L-antigens. Both antigens appeared to be largely particulate in character and did not display any obvious variant-specificity. Analysis of plasma from rhesus monkeys infected with the same antigenic variant showed the presence of band 1 antigen only.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D005779:Immunodiffusion; D008253:Macaca mulatta; D008288:Malaria / Q000276:immunology; D010961:Plasmodium / Q000276:immunology*
D000941:Antigens