title: [Lennox-Gastaut syndrome of late onset. I. Incidence of cases with onset before and after 6 years of age, etiological factors and intellectual level].
abstract: Of 66 patients with Lennox-Gastaut syndrome, 15 exhibited the first clinical manifestations after 6 years of age. Twelve of these were followed for a mean period of 2 years and 6 months, with neurological evaluations at about 2-month intervals. A review of the literature showed that, in 20% of the cases studied, the Lennox-Gastaut syndrome begins after the 6th year of life. Clinical evaluation allowed us to find out that our patients exhibited serious neurological damage preceding by several years the onset of the syndrome. The psychometric evaluation showed extensive involvement of the intellectual level, in contrast with the data in the literature on late-onset Lennox-Gastaut syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001927:Brain Diseases / Q000503:physiopathology* / Q000523:psychology; D002648:Child; D004832:Epilepsy, Absence / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology; D007360:Intelligence; D008297:Male; D013577:Syndrome
vernacular_title: Síndrome de Lennox-Gastaut com início tardio: I--Frequência de casos com início anterior e ulterior aos 6 anos de idade, fatores etiologicos e nível intelectual.