The glucose metabolism of adult Ostertagia circumcincta, in vitro.
Adult Ostertagia circumcincta from freshly killed sheep were incubated at 39 degrees C in a medium containing inorganic salts, antibiotics and D-[U-14C] glucose. The worms appeared healthy even after incubation for as long as 72 h. All the radioactivity was recovered either within the worms or in the incubation vessel in the form of metabolic products or unmetabolized glucose. Incubations were carried out at low oxygen tension except for those in which CO2 was measured. These were either aerobic or anaerobic. In terms of both quantity and radioactivity the main metabolic products of glucose were CO2, propan-1-ol, acetate and propionate. Smaller amounts of ethanol, lactate and succinate were formed. The results are compared with those found for the similar nematode Haemonchus contortus.
D000433:1-Propanol / Q000378:metabolism; D000085:Acetates / Q000378:metabolism; D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D010029:Ostertagiasis / Q000469:parasitology; D011422:Propionates / Q000378:metabolism; D014251:Trichostrongyloidea / Q000378:metabolism*
D000085:Acetates; D011422:Propionates; D002245:Carbon Dioxide; D000433:1-Propanol; D005947:Glucose