Antimicrobial activity of some salts of dialkylthiophosphoric acids.
A total of 18 derivatives of O,O-dialkylthio- and O,O-dialkylthiophosphoric acids were tested for antimicrobial activity using strains of Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Candida albicans. The activity was found to depend on the length of the alkyl substituent and/or the cation size. All derivatives were ineffective with E. coli and C. albicans.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009946:Organothiophosphorus Compounds / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D009946:Organothiophosphorus Compounds