title: Blood conservation techniques.
abstract: Increasing numbers of operations requiring cardiopulmonary bypass have been accompanied by greater demands for blood resources. Improved techniques of blood conservation have diminished the average blood requirements per operation and have increased the percent of operations that can be done without homologous blood. The conservation of blood can be planned according to each patient's requirements. The techniques include preoperative blood donation, intraoperative withdrawal of blood, reinfusion of oxygenator blood, autotransfusion of blood after heparin neutralization, autotransfusion after wound closure, and hemodilution. The availability of techniques for filtration, centrifugation, and washing of blood have improved the safety of autotransfusion. The techniques that gives the best cost/benefit ratio appear to be preoperative withdrawal of blood, reinfusion of centrifuged oxygenator contents, and reinfusion of filtered blood from chest drainage.
mesh_terms: D001803:Blood Transfusion / Q000191:economics / Q000379:methods*; D001804:Blood Transfusion, Autologous / Q000379:methods*; D002498:Centrifugation; D003362:Cost-Benefit Analysis; D005374:Filtration; D006438:Hemodilution; D006494:Heparin Antagonists; D006801:Humans; D007432:Intraoperative Period; D010106:Oxygenators; D011300:Preoperative Care; D011479:Protamines / Q000494:pharmacology
chemical_list: D006494:Heparin Antagonists; D011479:Protamines