title: Genetic and cytogenetic studies of malic enzyme in Drosophila melanogaster.
abstract: The genetic and cytogenetic locations of the structural gene (Men) for malic enzyme have been determined. Men maps genetically between kar and ry at 51.73 +/- 0.02. Cytogenetically, Men probably lies in the proximal edge of 87D1,2, based on the results of mapping utilizing a number of deficiencies with breakpoints in that region. A number of null alleles have been recovered; heterozygotes for these nulls and a Men deficiency are both viable and fertile. These findings are related to the one band, one functional unit model of salivary gland chromosome structure.
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004331:Drosophila melanogaster / Q000201:enzymology / Q000235:genetics*; D005260:Female; D005298:Fertility; D005796:Genes; D006579:Heterozygote; D008291:Malate Dehydrogenase / Q000235:genetics*; D008297:Male
chemical_list: D008291:Malate Dehydrogenase