Total body bone mineral and lean body mass by dual-photon absorptiometry. III. Comparison with trunk calcium by neutron activation analysis.
Dual-photon absorptiometry using 153Gd (44 and 100 keV) was used to measure the bone mineral content (BMC) of the trunk and of the total body (TBBM) in 7 volunteers with no overt bone disease. These values were compared to those obtained with partial-body neutron activation of calcium (trunk Ca). The trunk Ca seemed to represent best a 60 x 30 cm area; the correlation coefficient with the corresponding BMC in that area was 0.97 (SEE congruent to 7%). Trunk Ca was also highly correlated with TBBM (r = 0.96; SEE = 8%) and with radius BMC (r = 0.92; SEE = 11%), but the correlations with the BMC of smaller subareas of the trunk were lower (r congruent to 0.9; SEE approximately 12%). The BMC of the lumbar spine was only moderately correlated with trunk Ca, radius BMC and TBBM (r approximately 0.82; SEE approximately 18%), and only slightly more associated with trunk BMC (r approximately 0.88; SEE approximately 14%). The BMC of the combined lumbar-thoracic spine showed higher correlations with trunk Ca, radius BMC and TBBM (r approximately 0.87; SEE approximately 13%), and trunk BMC (r = 0.93; SEE approximately 10%). An accurate and sensitive measure of spinal status requires a direct measurement of that area.
D000328:Adult; D001823:Body Composition; D001842:Bone and Bones / Q000032:analysis*; D002118:Calcium / Q000032:analysis*; D005682:Gadolinium; D006801:Humans; D008903:Minerals / Q000032:analysis*; D009501:Neutron Activation Analysis / Q000379:methods; D011868:Radioisotopes; D013057:Spectrum Analysis / Q000379:methods
D008903:Minerals; D011868:Radioisotopes; D005682:Gadolinium; D002118:Calcium