[Effects of gangliosides on the in vitro growth of cultured spinal ganglia of guinea pigs. Preliminary results on a preparation of gangliosides from the cerebral cortex of cattle].
Brain bovine gangliosides added for 48 hrs. to the culture medium at concentrations ranging from 5.10(-5) mg/ml to 5.10(-7) mg/ml induced a statistically significant (p less than .005 to p less than 000,5) increase of the number of neurites of the outgrowth zone of guinea-pig spinal ganglia. On the contrary, the neurite length was only slightly increased.
D000818:Animals; D002417:Cattle; D002540:Cerebral Cortex / Q000032:analysis*; D046508:Culture Techniques; D005727:Ganglia, Spinal / Q000187:drug effects / Q000254:growth & development*; D005732:Gangliosides / Q000302:isolation & purification / Q000494:pharmacology*; D006168:Guinea Pigs
D005732:Gangliosides
Effets des gangliosides sur la croissance de ganglions spinaux de cobaye en culture in vitro. Résultats préliminaires concernant une préparation de gangliosides de cortex cérébral de boeuf.