title: Ventilatory response to isocapnic hypoxia in parents of victims of sudden infant death syndrome.
abstract: Ventilatory response to progressive isocapnic hypoxia was measured in 14 parents of victims of sudden infant death syndrome (SIDS) and 12 matched control parents. Controls had a value for a measure of ventilatory responsiveness (parameter A) of 200.8 +/- 46.4, while SIDS parents had a significantly lower value of 64.4 +/- 16.2 (P less than 0.01). Since degree of hypoxic ventilatory drive is a hereditary characteristic, it is concluded that a relatively low ventilatory responsiveness to hypoxia might have been present in the SIDS victims.
mesh_terms: D002245:Carbon Dioxide / Q000502:physiology; D006801:Humans; D010100:Oxygen / Q000502:physiology; D010290:Parents; D010313:Partial Pressure; D012119:Respiration; D012129:Respiratory Function Tests; D013398:Sudden Infant Death / Q000235:genetics*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen