[Action of salicylates on the disappearance of bacteria (Lactobacillus casei) phagocytized by polymorphonuclear cells].
This is a study of the modifications caused by acetylsalicylic acid and CuII (aspirinate)4 in the speed with which phagocytized bacteria disappear from polymorphonuclears (PMN) of the peritoneal exudate of guinea pigs. Acetylsalicylic acid inhibits the normal processes that cause the disappearance of the phagocytized bacteria; CuII (aspirinate)4, on the contrary, at low concentration (5 10(-6)) and during the first 45 minutes, causes an evident increase in the speed of disappearance of bacteria from PMN.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001241:Aspirin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006168:Guinea Pigs; D007780:Lacticaseibacillus casei; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*; D010587:Phagocytosis
D000893:Anti-Inflammatory Agents; C027058:tetrakis-mu-acetylsalicylato-dicopper(II); D001241:Aspirin
Azione di salicilati sulla scomparsa di batteri (Lactobacillus casei) fagocitati da polimorfonucleati.