title: Electron-beam treatment of scleromyxoedema.
abstract: A 42-year-old man is described with progressive scleromyxoedema. Clinical features included the development of transient central nervous system symptoms and a 5-year delay before the appearance of an IgG lambda-chain paraproteinaemia. Electron beam therapy resulted in significant improvement which lasted for 18 months.
mesh_terms: D000328:Adult; D006801:Humans; D007074:Immunoglobulin G; D007146:Immunoglobulin lambda-Chains; D008297:Male; D008855:Microscopy, Electron, Scanning; D009077:Mucins; D010265:Paraproteinemias / Q000209:etiology; D011882:Radiotherapy, High-Energy; D012867:Skin / Q000648:ultrastructure; D012871:Skin Diseases / Q000473:pathology / Q000532:radiotherapy*; D013997:Time Factors
chemical_list: D007074:Immunoglobulin G; D007146:Immunoglobulin lambda-Chains; D009077:Mucins