Repression of endo-1,4-beta-glucanase formation in Penicillium janthinellum and product inhibition of its 1,4-beta-glucanases and cellobiases.
Endo-1,4-beta-glucanase formation of Penicillium janthinellum was repressed by glucose, sophorose, and glycerol. Chromatography on DEAE-Sephadex A-50 was employed to separate the 1,4-beta-glucanases from two cellobiases. The 1,4-beta-glucanases were inhibited competitively by cellobiose and glucose, and the two cellobiases were inhibited by glucose and glucono-delta-lactone.
D002480:Cellulase / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D004794:Enzyme Repression; D005936:Glucans / Q000494:pharmacology; D005942:Gluconates; D005947:Glucose / Q000494:pharmacology; D005959:Glucosidases / Q000037:antagonists & inhibitors*; D005990:Glycerol / Q000494:pharmacology; D007700:Kinetics; D007783:Lactones; D010407:Penicillium / Q000201:enzymology*; D001617:beta-Glucosidase / Q000037:antagonists & inhibitors*
D005936:Glucans; D005942:Gluconates; D007783:Lactones; D005959:Glucosidases; D001617:beta-Glucosidase; D002480:Cellulase; D005947:Glucose; D005990:Glycerol; C010730:beta-glucono-1,5-lactone; C003328:sophorose