title: Inhibition of RNA synthesis in yeast protoplasts by a peptide factor from Tetrahymena cells.
abstract: Protoplasts of Schizosaccharomyces pombe, grown on a rich nutrient medium, were treated with a peptide factor isolated from cultures of the protozoan Tetrahymena pyriformis. The peptide factor is known to inhibit RNA synthesis in Tetrahymena. It has now been shown that the peptide factor also inhibits RNA synthesis in yeast protoplasts without affecting protein synthesis.
mesh_terms: D000818:Animals; D001203:Ascomycota / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005656:Fungal Proteins / Q000096:biosynthesis; D006131:Growth Inhibitors / Q000494:pharmacology*; D010455:Peptides / Q000494:pharmacology*; D012331:RNA, Fungal / Q000096:biosynthesis*; D012568:Schizosaccharomyces / Q000187:drug effects*; D013769:Tetrahymena pyriformis / Q000502:physiology*; D013997:Time Factors
chemical_list: D005656:Fungal Proteins; D006131:Growth Inhibitors; D010455:Peptides; D012331:RNA, Fungal