Oxygen-linked hydrogen ion binding of canine blood.
Decrease in hemoglobin oxygen saturation without change of true blood base-excess results in an increase in calculated base-excess because of differences in acidity between oxy- and deoxyhemoglobin. We have determined the mean +/- SE canine base-excess correction coefficient to be 0.43 +/- 0.01 mmol base per mmol heme, a value approximately 34% higher than the corresponding value for human hemoglobin.
D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004163:Diphosphoglyceric Acids / Q000097:blood; D004285:Dogs; D006418:Heme / Q000502:physiology; D006441:Hemoglobin A / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000502:physiology
D004163:Diphosphoglyceric Acids; D010108:Oxyhemoglobins; D002245:Carbon Dioxide; D006418:Heme; D006441:Hemoglobin A; D010100:Oxygen