The orofacial manifestations of the Lesch-Nyhan syndrome.
The Lesch-Nyhan syndrome is a rare sex-linked inborn error of purine metabolism characterised by hyperuricaemia, mental handicap, neurologic disorders, and self-destructive behaviour. The literature is reviewed and a 12-year-old patient exhibiting mutilation of the lip and tongue is reported.
D002648:Child; D003729:Dental Care; D006801:Humans; D007926:Lesch-Nyhan Syndrome / Q000473:pathology*; D008046:Lip / Q000293:injuries* / Q000473:pathology; D008297:Male; D012652:Self Mutilation / Q000473:pathology*; D014059:Tongue / Q000293:injuries* / Q000473:pathology