Sarcoma complicating von Recklinghausen disease in pregnancy.
Several cases of benign enlargment of neurofibromata during pregnancy are reported in the literature. We believe the present case to be the first report of malignant schwannoma occurring in such a tumor during pregnancy. As this case illustrates, malignant sarcomatous change must be carefully considered in such patients. Prompt diagnosis and radical therapy offer the only chance of survival in malignant schwannoma.
D000008:Abdominal Neoplasms / Q000150:complications*; D000328:Adult; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009456:Neurofibromatosis 1 / Q000150:complications*; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D011248:Pregnancy Complications; D012509:Sarcoma / Q000150:complications* / Q000601:surgery; D012583:Schwann Cells
D004317:Doxorubicin