title: [The use of pattern recognition for analysing the possible relation between molecular structure of polycyclic hydrocarbons and their carcinogenicity].
abstract: Pattern recognition has been used for investigating the part played by the molecular structure of polycyclic hydrocarbons in their carcinogenic action. A series of molecules has been considered, whose physicochemical properties are known to be closely related to the number and location of their aromatic rings. From a pattern recognition program and two learning subsets (carcinogenic and non carcinogenic molecules), it has been shown that (i) the shape of the molecule is correlated with its carcinogenic power; (ii) an index of carcinogenicity can be estimated for any molecule in the considered set.
mesh_terms: D002273:Carcinogens / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D008433:Mathematics; D008722:Methods; D010363:Pattern Recognition, Automated; D011083:Polycyclic Compounds / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D002273:Carcinogens; D011083:Polycyclic Compounds
vernacular_title: Utilisation de la "reconnaissance de formes" pour analyser le lien éventuel entre la structure moléculaire des hydrocarbures polybenzéniques et leur pouvoir cancérogène.