Sudden occlusion of a saphenous vein bypass graft relieved by direct injection of nitroglycerin.
An unusual case of sudden occlusion of a saphenous vein bypass graft to the right coronary artery, during a coronary angiographic study, is presented. Such occlusion was relieved by direct intragraft nitroglycerin injection, as typically happens in case of coronary arterial spasm. A possible pathogenetic mechanism, based on the present knowledge of platelet aggregation and the role of the powerful vasoactive agent Thromboxane A2, is discussed.
D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage* / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy*; D012501:Saphenous Vein / Q000637:transplantation*; D014182:Transplantation, Autologous
D005996:Nitroglycerin