Rh(D) fraction incompatibility causing hemolytic disease of the newborn. Report of two cases in a Chinese family.
Two cases of hemolytic disease of new born in a Chinese family are reported. The hemolysis was due to the production in the mother of antibodies against fractions A, C, and D of Rh(D) antigen. The fractions were absent in the mother's red blood cells which are Rh(DB) but present in her babies. Rh(DB) may be detected by the use of two types of anti-D sera, one with and the other without anti-DB activity. For transfusion purpose, all DB patients so tested, would be regarded as Rh(D) negative.
D000328:Adult; D000906:Antibodies / Q000032:analysis; D002681:China / Q000208:ethnology; D004899:Erythroblastosis, Fetal / Q000235:genetics* / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007564:Japan; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D000906:Antibodies; D012204:Rh-Hr Blood-Group System