L-serine degradation in Escherichia coli K-12: a combination of L-serine, glycine, and leucine used as a source of carbon.
Escherichia coli K-12 strain CU1008 cannot use L-serine as the sole carbon source, but it could use L-serine as an auxiliary carbon source with glucose, L-alanine, or pyruvate and could derive energy from L-serine to support oxygen uptake. CU1008 grew with L-serine if it was also provided with glycine and leucine. These may act by increasing the available activity of L-serine deaminase; other explanations are also explored.
D004734:Energy Metabolism; D004926:Escherichia coli / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D005998:Glycine / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D010101:Oxygen Consumption; D012694:Serine / Q000378:metabolism*; D014305:Triose-Phosphate Isomerase / Q000378:metabolism
D012694:Serine; D014305:Triose-Phosphate Isomerase; D007930:Leucine; D005947:Glucose; D005998:Glycine