title: [Electron microscopical investigations on islets of Langerhans in sand rats (Psammomys obesus) before manifestation of diabetes mellitus (author's transl)].
abstract: Electron microscopical investigations of islets of Langerhans are carried out in "protodiabetic" sand rats. In the B-cells and beta-Granules (2 to 5) aggregated. Mitochondrias, Golgi apparatus and rough endoplasmic reticulum are increased. These B-cells are stimulated. The A-cells are degranulated, and lipofuscin-granules are in the cytoplasm present. These cells were stimulated too. The D-cells are not stimulated.
mesh_terms: D000818:Animals; D003411:Arvicolinae; D003921:Diabetes Mellitus, Experimental / Q000473:pathology*; D007515:Islets of Langerhans / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011236:Prediabetic State / Q000473:pathology*
vernacular_title: Elektronenmikroskopische Untersuchungen an Langerhansschen Inseln von Sandratten (Psammomys obesus) vor Diabetesmanifestation).