title: Continuous positive airway pressure in bronchiolitis.
abstract: Over five years 23 infants with evidence of respiratory insufficiency due to bronchiolitis were managed with continuous positive airway pressure (CPAP). This was applied through either a short nasal cannula (14 patients) or an endotracheal tube (nine patients). Clinical improvement was seen in all patients, and there were significant falls in mean respiratory and pulse rates and pressure of carbon dioxide (PCO2). Seven infants with PCO2 values exceeding 8.0 KPa (60.2 mm Hg) responded particularly well. CPAP is effective in bronchiolitis, and when applied by the nasal route it is relatively free from complications.
mesh_terms: D001990:Bronchiolitis, Viral / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D002245:Carbon Dioxide / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010313:Partial Pressure; D011175:Positive-Pressure Respiration; D011674:Pulse; D012119:Respiration
chemical_list: D002245:Carbon Dioxide