title: A flexible system for closed-loop ventilator development.
abstract: The feasibility of using a microcomputer to regulate the delivery of artificial ventilation was investigated experimentally. To carry out this study, a sampled-data proportional, integral, derivative feedback controller was implemented on a commercial microcomputer and interfaced with a digital/analogue model of a prototype ventilator and two-compartment patient. The microcomputer sampled end-tidal CO2 and calculated a new frequency of ventilation from the difference of end-tidal CO2 and a desired set point value. Use of a microcomputer programmable in BASIC allowed easy manipulation of feedback structure. With the proper choice of feedback constants, the microcomputer was able to maintain end-tidal CO2 at a desired set point.
mesh_terms: D002245:Carbon Dioxide / Q000378:metabolism; D003201:Computers; D005246:Feedback; D006801:Humans; D008838:Microcomputers; D012122:Ventilators, Mechanical
chemical_list: D002245:Carbon Dioxide