Hyperglobulinemic purpura in the course of multiple myeloma.
Secondary hyperglobulinemic purpura of Waldenström is characterized by polyclonal gammopathy associated mainly with autoimmune diseases. Its occurrence with multiple myeloma is very rare. We described a patient who developed characteristic lesions of hyperglobulinemic purpura in the course of IgA myeloma. Skin biopsy revealed deposition of IgA in the blood vessels.
D000368:Aged; D001808:Blood Vessels / Q000276:immunology / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D009101:Multiple Myeloma / Q000150:complications*; D011694:Purpura, Hyperglobulinemic / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000098:blood supply / Q000473:pathology
D007070:Immunoglobulin A