title: Otitis media with effusion: results of treatment with a short course of oral prednisone or intranasal beclomethasone aerosol.
abstract: A short course of prednisone suspension given in a decreasing dosage schedule for up to ten days was often effective (68%) in resolving mucoid otitis media with effusion (OME, middle ear effusion). No significant side effects were noted. Concommitant administration of sulfisoxazole suspension may have reduced the likelihood of activation of a quiescent infection of the middle ear. During the eight-month mean follow-up period, reaccumulation of the effusion was detected in 21% of the successfully treated children. Preliminary results of an unrelated, pilot project using intranasal beclomethasone dipropionate aerosol suggests that this novel method also may be efficacious in the treatment of OME.
mesh_terms: D000284:Administration, Oral; D000336:Aerosols; D001507:Beclomethasone / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D009666:Nose; D010033:Otitis Media / Q000188:drug therapy*; D010034:Otitis Media with Effusion / Q000188:drug therapy; D011241:Prednisone / Q000008:administration & dosage*; D012008:Recurrence; D013997:Time Factors
chemical_list: D000336:Aerosols; D001507:Beclomethasone; D011241:Prednisone