Ly-15: a new murine lymphocyte alloantigenic locus.
Immunization between CXB recombinant inbred mice selected for their identity at known loci led to the production of antisera recognizing two specificities: the previously described Ly-9.2 alloantigen and a new specificity, Ly-15.1. A monoclonal antibody to the Ly-15.2 specificity is also described. The Ly-15 specificities were found on thymus, on lymph node and spleen cells, and on liver, but were absent from kidney, brain, and red blood cells.
D000818:Animals; D000906:Antibodies; D000911:Antibodies, Monoclonal; D002874:Chromosome Mapping; D003602:Cytotoxicity, Immunologic; D007106:Immune Sera / Q000494:pharmacology; D007519:Isoantigens / Q000235:genetics*; D008099:Liver / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008814:Mice, Inbred NZB; D008815:Mice, Inbred Strains; D011995:Recombination, Genetic; D012397:Rosette Formation
D000906:Antibodies; D000911:Antibodies, Monoclonal; D007106:Immune Sera; D007519:Isoantigens