Changing patterns of Pseudomonas aeruginosa antibiotic sensitivity.
Using a sample of 71 Pseudomonas aeruginosa infected burns patients admitted to the Burns Injury Unit of the Royal Brisbane Hospital within an 11-year period the pattern of sensitivity of the organism to 18 antibiotics was studied longitudinally looking at first and last cultures (either pus, blood or sputum) separately. Only 5 antibiotics reflected a significant change (towards resistance) in sensitivity patterns (chloramphenicol, gentamycin, kanamycin, tetracycline, achromycin). Six of the other 13 antibiotics showed a trend towards increasing resistance but the changes were not statistically significant (polymyxin B, carbenicillin, sulphanomides, cotrimoxazole, streptomycin, teramycin). The other 7 antibiotics showed no change, all but one (colistin) being resistant throughout.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002056:Burns / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D002648:Child; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000150:complications / Q000188:drug therapy; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D012189:Retrospective Studies
D000900:Anti-Bacterial Agents