Effects of lithium carbonate on methylphenidate-induced mood, behavior, and cognitive processes.
Evidence is presented which suggests that lithium modifies the mood and behavioral alterations resulting from IV methylphenidate. Specifically, lithium significantly reduces the level of arousal-activation, euphoria-grandiosity, and the total score of manic-state ratings following a methylphenidate challenge. In addition, lithium appears to be capable of modifying the growth hormone response to methylphenidate.
D000328:Adult; D001143:Arousal / Q000187:drug effects; D001519:Behavior / Q000187:drug effects*; D003071:Cognition / Q000187:drug effects; D004347:Drug Interactions; D005059:Euphoria / Q000187:drug effects; D006801:Humans; D008094:Lithium / Q000494:pharmacology*; D016651:Lithium Carbonate; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology*; D008875:Middle Aged
D008774:Methylphenidate; D016651:Lithium Carbonate; D008094:Lithium