The inhibition of photosynthetic electron transfer in Rhodospirillum rubrum by N ,N' -dicyclohexylcarbodiimide.
N ,N' -Dicyclohexylcarbodiimide (DCCD) at concentrations above 0.1 mM inhibits light-induced generation of a membrane potential in the course of cyclic and non-cyclic electron transfer, as well as light-induced oxygen uptake due to interaction of photoreduced secondary (loosely bound) ubiquinone with O2 in Rhodospirillum rubrum chromatophores. Similarly to o-phenanthroline, DCCD blocks the electron transfer in the chromatophores between the primary (tightly bound) and secondary ubiquinones.
D002234:Carbodiimides / Q000494:pharmacology*; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology; D004024:Dicyclohexylcarbodiimide / Q000494:pharmacology*; D004579:Electron Transport / Q000187:drug effects; D007700:Kinetics; D008027:Light; D008564:Membrane Potentials / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D010788:Photosynthesis / Q000187:drug effects*; D012247:Rhodospirillum rubrum / Q000187:drug effects / Q000378:metabolism*
D002234:Carbodiimides; D004024:Dicyclohexylcarbodiimide; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone