[Use of CO2 euthanasia cabinet for experimental animals (author's transl)].
The process of CO2 euthanasia on mouse, rat, guinea pig and rabbit was observed using a CO2 euthanasia cabinet. The cabinet was filled with CO2 gas and the caged animal was placed into the cabinet. These animals quietly collapsed and their respiratory movement ceased within 25--225 seconds. A-V block was the first arrhythmia recognized on ECG in all cases. The arrhythmia recorded on ECG included complete A-V block, A-V dissociation, ventricular escape rhythm, atrial fibrillation, ventricular flutter and ventricular fibrillation. It could be concluded that euthanasia was satisfactorily performed on these species by means of the CO2 euthanasia cabinet.
D000818:Animals; D000830:Animals, Laboratory; D002245:Carbon Dioxide; D005065:Euthanasia / Q000662:veterinary*; D006168:Guinea Pigs; D051379:Mice; D011817:Rabbits; D051381:Rats
D002245:Carbon Dioxide