Transient osteosclerosis associated with sodium valproate.
A 15-year-old boy on sodium valproate presented with pain in the extremities which had not responded to aspirin. X-ray of the long bones showed increased density in the metaphyses. After discontinuation of the drug his symptoms and the X-ray abnormalities disappeared.
D000293:Adolescent; D004832:Epilepsy, Absence / Q000188:drug therapy; D006801:Humans; D008297:Male; D010026:Osteosclerosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011859:Radiography; D014635:Valproic Acid / Q000009:adverse effects*
D014635:Valproic Acid