Antitumor activities and estrogen receptor interactions of the metabolites of the antiestrogens C1628 and U23,469 in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor system.
D015127:9,10-Dimethyl-1,2-benzanthracene; D000818:Animals; D001667:Binding, Competitive; D003600:Cytosol / Q000378:metabolism; D004958:Estradiol / Q000378:metabolism; D004965:Estrogen Antagonists / Q000378:metabolism / Q000627:therapeutic use*; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy* / Q000378:metabolism; D009281:Naphthalenes / Q000627:therapeutic use*; D009594:Nitromifene / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010544:Peroxidases; D011409:Propylene Glycols / Q000378:metabolism / Q000627:therapeutic use*; D011759:Pyrrolidines / Q000494:pharmacology*; D051381:Rats; D011960:Receptors, Estrogen / Q000378:metabolism*; D013764:Tetrahydronaphthalenes / Q000378:metabolism / Q000627:therapeutic use*; D014599:Uterus / Q000187:drug effects / Q000378:metabolism
D004965:Estrogen Antagonists; D009281:Naphthalenes; D011409:Propylene Glycols; D011759:Pyrrolidines; D011960:Receptors, Estrogen; D013764:Tetrahydronaphthalenes; C014291:U 23469; D004958:Estradiol; D015127:9,10-Dimethyl-1,2-benzanthracene; D009594:Nitromifene; D010544:Peroxidases