Balance of glucose utilization in rabbit reticulocytes.
The shares of glucose utilizing processes in red blood cells under aerobic conditions were estimated in tracer experiments and with mathematical methods. A complex method of these pathways in reticulocytes is given. Our approach to the solution of the problem in reticulocytes can be transferred to other tissues. The new mathematical technique used is suitable for derivation of closed terms for the specific radioactivity of single positions of C-atoms of the metabolites of citrate cycle. Therefore, by means of regressions analysis, the calculation of unknown concentrations and flux rates is possible.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002245:Carbon Dioxide / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D006019:Glycolysis; D007700:Kinetics; D011817:Rabbits; D012156:Reticulocytes / Q000378:metabolism*
D001786:Blood Glucose; D002245:Carbon Dioxide