Rapid regression of a suprasellar extending prolactinoma after bromocriptine treatment during pregnancy.
A patient is described with hyperprolactinemia, post-pill amenorrhea, galactorrhea, and a normal pituitary fossa. Pregnancy occurred after induction of ovulation with bromocriptine. During pregnancy rapidly increasing visual field defects due to suprasellar extension of a pituitary tumor were observed. Operation was advised but refused. The patient was treated with bromocriptine in a dose of 15 mg daily, which resulted in normalization of the bitemporal hemianopia within 2 weeks.
D000328:Adult; D000568:Amenorrhea / Q000175:diagnosis; D001971:Bromocriptine / Q000627:therapeutic use*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005687:Galactorrhea / Q000175:diagnosis; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D011863:Radioimmunoassay; D012658:Sella Turcica / Q000473:pathology*; D013974:Thyroxine / Q000097:blood; D013997:Time Factors
D001971:Bromocriptine; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013974:Thyroxine