title: [Effect of glycerol, mannitol, and lasix on cerebrospinal fluid pressure in the acute period of a stroke].
abstract: On giving a dose of glycerol (orally), mannitol or lasix (intravenously) to patients with a cerebral stroke in the acute period the cerebrospinal fluid (CSF) pressure in them dropped, on the average, by 70-80%, 65-70%, and 25-30%, respectively. However in 6.5 to 7.5 hours it rose again and the after-effect phenomenon appeared. The effects of the drugs having been over, the CSF pressure was found to exceed the initial level by 50-60% after the glycerol intake; by 75 to 80% after the mannitol, an by 4 to 6% after the lasix injections. When glycerol, mannitol, and lasix were given rectally the CSF pressure dropped, respectively, by 35-45%, 35-40%, and 20-25% below the initial level, and did not rise throughout the whole period of the observation.
mesh_terms: D000208:Acute Disease; D001929:Brain Edema / Q000517:prevention & control*; D002545:Brain Ischemia / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D002543:Cerebral Hemorrhage / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D005260:Female; D005665:Furosemide / Q000627:therapeutic use*; D005990:Glycerol / Q000627:therapeutic use*; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D008353:Mannitol / Q000627:therapeutic use*
chemical_list: D008353:Mannitol; D005665:Furosemide; D005990:Glycerol
vernacular_title: O vliianii glitserina, mannitola i laziksa na likvornoe davlenie v ostrom periode pozgovogo insul'ta.