Inactivation of thymidylate synthetase by a novel mechanism-based enzyme inhibitor: 1-(beta-D-2'-deoxyribofuranosyl) 8-azapurin-2-one 5'-monophosphate.
D001665:Binding Sites; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000201:enzymology; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D011685:Purine Nucleotides / Q000494:pharmacology*; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors*
D011685:Purine Nucleotides; C032528:2-deoxyribosyl-8-azapurine-2-one 5'-monophosphate; D008780:Methyltransferases; D013940:Thymidylate Synthase