title: [Hyperbilirubinemia in liver diseases].
abstract: Jaundice is often the first and sometimes the only symptom of liver disease. Besides in parenchymal liver disease jaundice is also observed in chronic non-haemolytic hyperbilirubinemias (Crigler-Najjar type I and II, Gilbert's syndrome) and in hereditary conjugated hyperbilirubinaemias (Dubin-Johnson- and Rotor-syndrome). A specific therapy is only available for Crigler-Najjar type II which is treated with phenobarbitone.
mesh_terms: D045930:Anabolic Agents / Q000009:adverse effects; D003414:Crigler-Najjar Syndrome / Q000209:etiology; D004967:Estrogens / Q000009:adverse effects; D005878:Gilbert Disease / Q000209:etiology; D014453:Glucuronosyltransferase / Q000172:deficiency; D006801:Humans; D006932:Hyperbilirubinemia / Q000139:chemically induced / Q000209:etiology*; D007566:Jaundice, Chronic Idiopathic / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications; D008107:Liver Diseases / Q000150:complications*; D013448:Sulfobromophthalein / Q000378:metabolism
chemical_list: D045930:Anabolic Agents; D004967:Estrogens; D013448:Sulfobromophthalein; D014453:Glucuronosyltransferase
vernacular_title: Hyperbilirubinämie bei Leberekrankungen.