title: Effect of physical effort on the white blood cells in benign familial leukopenia.
abstract: The components of the peripheral white blood cells (WBC) were determined before and after 10 min of submaximal ergometric work in two groups of subjects: 34 healthy Yemenite Jews with benign familial leukopenia (BFL) and 34 healthy Yemenite Jews without BFL. The mean +/- SEM of the increase in the peripheral WBC following the effort in the control group was 2,606 +/- 1,272 cells/mm3, due to the relative rise in the neutrophils, eosinophils, monocytes and lymphocytes. The identical ergometric work, performed by BFL subjects, brought about significantly lower increase (700 +/- 865 cells/mm3) in the peripheral WBC, the majority of which were lymphocytes. It seems that subjects with this form of BFL lack granulocytes in the marginal pool.
mesh_terms: D000293:Adolescent; D000328:Adult; D004804:Eosinophils / Q000166:cytology; D005260:Female; D006801:Humans; D007557:Israel; D007585:Jews; D007958:Leukocyte Count; D007970:Leukopenia / Q000097:blood / Q000235:genetics*; D008214:Lymphocytes / Q000166:cytology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000166:cytology; D009504:Neutrophils / Q000166:cytology; D005082:Physical Exertion; D015006:Yemen / Q000208:ethnology