Preparation of drugs used in hyperacidity. Part IV. Effect of sulphate, chloride and nitrate ions and mannitol on neutralizing properties and changes of alumina gels.
The stability of alumina gels precipitated from the appropriate aluminum salts with ammonia solution have been investigated. The effect of SO42-, Cl-, NO3-ions and mannitol on this stability was evaluated. SO42-ions, and to a lesser degree also Cl- and NO3-ions stabilize alumina gel due to the incorporation in its structure. The use of mannitol solution as a suspension medium results also in the complete stabilization of the gel.
D000536:Aluminum Hydroxide; D000863:Antacids; D002712:Chlorides; D004355:Drug Stability; D008353:Mannitol; D009566:Nitrates; D013431:Sulfates
D000863:Antacids; D002712:Chlorides; D009566:Nitrates; D013431:Sulfates; D008353:Mannitol; D000536:Aluminum Hydroxide