Evaluation of the agar-gel immunodiffusion test in the diagnosis of canine blastomycosis.
The agar-gel immunodiffusion test was used to evaluated 35 dogs with histopathologically confirmed blastomycosis and 98 dogs without blastomycosis. The test had a sensitivity of 91% and a specificity of 96%. Thirteen of the dogs treated for blastomycosis were tested at 6 to 33 months after treatment with amphotericin B. Ten of 13 dogs became seronegative and 3, though clinically normal, remained seropositive at 19, 20, and 20 months, respectively, after amphotericin treatment.
D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D000908:Antibodies, Fungal / Q000032:analysis; D001758:Blastomyces / Q000276:immunology; D001759:Blastomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D005779:Immunodiffusion / Q000662:veterinary*
D000908:Antibodies, Fungal; D000666:Amphotericin B