Gentamicin-carbenicillin synergy among gentamicin resistant Pseudomonas aeruginosa.
Forty-five isolates of gentamicin resistant Pseudomonas aeruginosa were evaluated for gentamicin-carbenicillin synergy. Only 9 percent (4/45) showed synergy. Of nine isolates with demonstrable zones around a gentamicin disc (8 to 12 mm), none showed a synergistic response. Effective treatment of gentamicin resistant Ps. aeruginosa with gentamicin and carbenicillin should not be assumed without additional test procedures.
D002228:Carbenicillin / Q000494:pharmacology*; D004357:Drug Synergism; D005839:Gentamicins / Q000494:pharmacology*; D010403:Penicillin Resistance; D011550:Pseudomonas aeruginosa / Q000187:drug effects*
D005839:Gentamicins; D002228:Carbenicillin