Sertoli cell tumour in a true hermaphrodite: suggestive evidence for ectopic gonadotrophin production by the tumour. Case report.
A Sertoli cell tumour that occurred in a true hermaphrodite with a 46, XX chromosome constitution is described. Removal of the tumour was followed by an immediate fall in plasma FSH and LH concentrations. It is suggested that the tumour possessed the capacity for ectopic production of the gonadotrophins.
D000293:Adolescent; D000328:Adult; D012734:Disorders of Sex Development / Q000150:complications*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D008297:Male; D012707:Sertoli Cell Tumor / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D013736:Testicular Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone