title: Pulmonary emboli associated with coagulum pyelolithotomy.
abstract: Coagulum pyelolithotomy has become a popular means to extract renal calculi in selected circumstances. Serious complications with this procedure have not been previously reported. A case report of an operative death due to a pulmonary embolus is presented, because of which we designed a canine laboratory study to determine the relationship between coagulum injection into the renal pelvis and thrombo-embolic phenomena. Positive lung scans were detected in a large number of animals related to the volume of the coagulum used and the concentration of the thrombin injected. Judicious use of this procedure with suggested cautions is proposed.
mesh_terms: D000818:Animals; D004285:Dogs; D005169:Factor VIII / Q000008:administration & dosage; D005340:Fibrinogen / Q000008:administration & dosage; D006801:Humans; D007669:Kidney Calculi / Q000628:therapy; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D011655:Pulmonary Embolism / Q000209:etiology*; D013917:Thrombin / Q000008:administration & dosage
chemical_list: C026912:cryoprecipitate coagulum; D005169:Factor VIII; D005340:Fibrinogen; D013917:Thrombin