Altered expression of histocompatibility antigens on "B" large cell lymphomas.
We describe three malignant lymphomas of the diffuse "histiocytic" (large noncleaved) type in which most of the large lymphoid cells express monoclonal surface immunoglobulin and HLA-DR antigens but do not express HLA-A,B,C, or beta-2-microglobulin as assessed by indirect immunofluorescence.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D002469:Cell Separation; D006041:Goats; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D007142:Immunoglobulin gamma-Chains; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D007148:Immunoglobulin mu-Chains; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D011947:Receptors, Antigen, B-Cell; D001613:beta 2-Microglobulin / Q000276:immunology
D006680:HLA Antigens; D007142:Immunoglobulin gamma-Chains; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains; D007148:Immunoglobulin mu-Chains; D011947:Receptors, Antigen, B-Cell; D001613:beta 2-Microglobulin