Antiviral drugs: modes of action and strategies for therapy.
The understanding of viral metabolism, particularly the molecular basis of enzyme interactions governing replication of viruses, is one of the basic challenges in the relatively new field of antiviral chemotherapy. Although a few agents have shown documented efficacy and safety in the treatment of influenza A and herpes simplex infections, the search through myriad antiviral candidates continues.
D000998:Antiviral Agents / Q000627:therapeutic use*; D004279:DNA, Viral / Q000037:antagonists & inhibitors*; D006561:Herpes Simplex / Q000188:drug therapy; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy; D019384:Nucleic Acid Synthesis Inhibitors; D014777:Virus Diseases / Q000201:enzymology*
D000998:Antiviral Agents; D004279:DNA, Viral; D019384:Nucleic Acid Synthesis Inhibitors