title: Aluminium sucrose biscuit fillings to control hyperphosphataemia in patients undergoing dialysis.
abstract: Aluminium hydroxide is used to prevent hyperphosphataemia in patients undergoing dialysis, but many standard preparations are unpalatable. In this study hydrated aluminium sucrose was suspended in synthetic cream and used as a biscuit filling. Six patients undergoing dialysis took part in five five-week study periods comparing different forms of treatment. No significant difference was found between serum phosphate concentrations measured during standard treatment and those measured during treatment with aluminium sucrose biscuits. There was no significant difference in serum phosphate concentrations when the patients were given placebo biscuits and when they received no treatment. Aluminium sucrose presented in this form was an adequate phosphate binder and was acceptable to the patients.
mesh_terms: D000535:Aluminum / Q000008:administration & dosage / Q000627:therapeutic use*; D004339:Drug Compounding / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood*; D006435:Renal Dialysis / Q000009:adverse effects*; D013392:Sucralfate
chemical_list: D010710:Phosphates; D013392:Sucralfate; D000535:Aluminum