[Mechanism of renal elimination of 2 elements of group IIIA of the periodic table : aluminum and indium].
Aluminium and indium, two elements of group IIIA of the periodic table, are concentrated by the kidney inside lysosomes of proximal tubule cell. In these lysosomes, aluminium and indium are precipitated as non-soluble phosphate salts and these precipitates are then expelled in the tubular lumen and eliminated with the urinary flow. These data have been visualized by analytical microscopy (ion microscopy and X ray microanalysis). Local acid phosphatases are assumed to permit the concentration of aluminium and indium salts inside the lysosomes.
D000535:Aluminum / Q000378:metabolism*; D000818:Animals; D007204:Indium / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000648:ultrastructure; D008247:Lysosomes / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats; D012964:Sodium / Q000032:analysis
D007204:Indium; D012964:Sodium; D000535:Aluminum
Mécanisme d'élimination rénale de deux éléments du groupe IIIA de la classification périodique : l'aluminium et l'indium.