Hypothyroidism and prolactin.
Hypothyroidism-induced hyperprolactinemia, with or without clinical manifestations, is reported in a short case in addition to the results of basal and thyrotropin-releasing hormone (TRH)-induced prolactin values in primary hypothyroidism. In comparison with an age- and sex-matched group, basal- (P less than 0.02) and TRH-induced (P less than 0.02) prolactin values are significantly increased in primary hypothyroidism. A review of the literature and the possible pathogenesis of hyperprolactinemia, amenorrhea and galactorrhea are discussed. No correlation could be found between maximal thyrotropin (TSH) and prolactin-increase values.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000568:Amenorrhea / Q000097:blood; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D014284:Triiodothyronine; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin; D013974:Thyroxine