Cholinergic stimulation of glucose transport in human erythrocytes.
The effects of cholinergic stimulation on glucose equilibrium exchange rate have been studied in human erythrocytes. Carbamylcholine increases in V of equilibrium exchange by 20% but has no significant effect on Km. The cholinergic effect is abolished by the muscarinic antagonist atropine or by alterations in intracellular calcium concentrations induced by the calcium ionophore A23187.
D001285:Atropine / Q000494:pharmacology*; D001693:Biological Transport, Active / Q000187:drug effects; D001786:Blood Glucose / Q000378:metabolism*; D000001:Calcimycin / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology*; D004533:Egtazic Acid / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D007700:Kinetics
D001786:Blood Glucose; D000001:Calcimycin; D004533:Egtazic Acid; D001285:Atropine; D002217:Carbachol