Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses.
Fv-4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre-I (prealbumin) and Igh-I (immunoglobulin heavy-chain constant region) loci on chromosome 12 in mice. The gene order was Fv-4 - Pre-I - Igh-I, and the estimated frequency of recombination between Fv-4 and Pre-I was about 20%.
D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005622:Friend murine leukemia virus / Q000276:immunology*; D005802:Genes, MHC Class II; D005819:Genetic Markers; D006183:H-2 Antigens / Q000235:genetics*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*; D011228:Prealbumin / Q000235:genetics
D005819:Genetic Markers; D006183:H-2 Antigens; D007143:Immunoglobulin Heavy Chains; D011228:Prealbumin