Pseudogynecomastia due to neurofibromatosis--a light microscopic and ultrastructural study.
A six year old boy with bilateral breast enlargement was found to have a normal endocrine status. Resected tissue revealed the features of pseudogynecomastia due to a proliferation of fibrous tissue traversed by neuroid structures. Multinucleated giant cells were present within the fibrous tissue. Ultrastructural study revealed organized nerve elements in a collagenous stroma. The multinucleated giant cells appeared to be variants of the predominant stromal fibroblasts.
D001940:Breast / Q000648:ultrastructure; D002648:Child; D003937:Diagnosis, Differential; D004702:Endocrine Glands / Q000502:physiology; D006177:Gynecomastia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000648:ultrastructure; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology