A comparative study of enflurane and halothane in children.
Equipotent concentrations of enflurane and halothane inhaled by children caused substantial hypotension and respiratory depression, these changes being more pronounced with the former agent. Plasma catecholamine levels were unaltered indicating that enflurane, like halothane, elicits little sympatho-adrenal response. Induction of anaesthesia and recovery times were largely comparable but earlier and more frequent use of narcotic analgesics was required after enflurane anaesthesia.
D000769:Anesthesia, Inhalation; D001794:Blood Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000502:physiology; D002648:Child; D004737:Enflurane / Q000494:pharmacology*; D005260:Female; D006221:Halothane / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D012119:Respiration / Q000187:drug effects; D013990:Tidal Volume
D002245:Carbon Dioxide; D004737:Enflurane; D006221:Halothane