[Prenatal diagnosis of sex by determination of amniotic testosterone and FSH].
Among hormones which can be determined in the amniotic fluid in the mid-pregnancy period, testosterone and F.S.H. allow the best discrimination between sexes (Figure 1). Moreover, F.S.H. is clearly increasing during the 2d trimester of pregnancy in case of a female fetus. This is a quick and reliable method which uses a small quantity of amniotic fluid. Combined with chromosomal analysis, it increases the accuracy of the sex diagnosis and indicates a repeat amniocentesis if there is a discrepancy between karyotype and hormonal determinations.
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000378:metabolism*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D012732:Sex Determination Analysis; D013739:Testosterone / Q000378:metabolism*
D013739:Testosterone; D005640:Follicle Stimulating Hormone
Diagnostic prénatal du sexe par dosage de la testostérone et de la F.S.H. amniotiques.