Inhibition of DMBA carcinogenesis of hamster buccal pouch by phenanthrene and dimethylnaphthalene.
Phenanthrene (Phe) and to a lesser degree 1,4-dimethylnaphthalene (DMeN) were each found to retard the development of epidermoid carcinomas in hamster buccal pouch induced by the thrice weekly application of a 0.5 per cent solution of 7,12-dimethylbenz[a]anthracene (DMBA) in heavy mineral oil.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000037:antagonists & inhibitors*; D000818:Animals; D001551:Benz(a)Anthracenes / Q000037:antagonists & inhibitors*; D002610:Cheek; D006224:Cricetinae; D005260:Female; D008297:Male; D008647:Mesocricetus; D009062:Mouth Neoplasms / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control*; D009281:Naphthalenes / Q000494:pharmacology*; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology / Q000517:prevention & control; D010616:Phenanthrenes / Q000494:pharmacology*; D013997:Time Factors
D001551:Benz(a)Anthracenes; D009281:Naphthalenes; D010616:Phenanthrenes; C031181:phenanthrene; D015127:9,10-Dimethyl-1,2-benzanthracene; C031969:1,4-dimethylnaphthalene