Spontaneous pregnancy and its outcome after human menopausal gonadotropin/human chorionic gonadotropin-induced pregnancy.
The fertility in previously sterile women who conceived at least once following hMG/hCG-induced ovulation is investigated. The study comprises 141 women. The cumulative spontaneous pregnancy rate (CSPR) was calculated using life table analysis and was found to be 30.4% after 5 years. The CSPR for subsequent pregnancies reached 91.3% after 5 years. This figure is similar to that of normal parous women, although the study group (previously infertile women) requires a larger exposure period to attain the figure. The spontaneous abortion rate in the hMG/hCG-induced pregnancies was 29%; whereas in subsequent spontaneous pregnancies this rate was 8.8%. This difference in rate was found to be statistically significant, and the possible reasons are discussed.
D000022:Abortion, Spontaneous; D000568:Amenorrhea / Q000188:drug therapy; D000858:Anovulation / Q000188:drug therapy*; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D005260:Female; D005687:Galactorrhea / Q000503:physiopathology; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008596:Menotropins / Q000627:therapeutic use*; D008598:Menstruation; D009839:Oligomenorrhea / Q000188:drug therapy; D010062:Ovulation Induction; D049590:Postpartum Period; D011247:Pregnancy / Q000187:drug effects*
D006063:Chorionic Gonadotropin; D008596:Menotropins