The degradation of glycoconjugates in the human gastric mucous membrane.
Autolysis of a homogenate from the human gastric mucosa results in the release of the reducing substances into the supernatant. The activities of the six glycosidases from the human gastric mucosa, N-acetyl-beta-glucosaminidase, N-acetyl-Beta-galactosaminidase, alpha-fucosidase, beta-galactosidase, alpha-mannosidase and alpha-glucosidase were determined. Certain properties of the enzymes are described. The significance of these enzymes in glycoprotein catabolism in the human gastric mucosa is discussed.
D000118:Acetylglucosaminidase / Q000378:metabolism; D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000201:enzymology; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology*; D006023:Glycoproteins / Q000378:metabolism*; D006026:Glycoside Hydrolases / Q000378:metabolism*; D006596:Hexosaminidases / Q000378:metabolism; D006801:Humans; D008297:Male; D008361:Mannosidases / Q000378:metabolism; D008875:Middle Aged; D013276:Stomach Ulcer / Q000201:enzymology; D000520:alpha-Glucosidases / Q000378:metabolism; D005644:alpha-L-Fucosidase / Q000378:metabolism; D043323:alpha-Mannosidase; D001616:beta-Galactosidase / Q000378:metabolism; D048828:beta-N-Acetyl-Galactosaminidase
D006023:Glycoproteins; D006026:Glycoside Hydrolases; D006596:Hexosaminidases; D008361:Mannosidases; D000520:alpha-Glucosidases; D001616:beta-Galactosidase; D043323:alpha-Mannosidase; D005644:alpha-L-Fucosidase; D000118:Acetylglucosaminidase; D048828:beta-N-Acetyl-Galactosaminidase