Another hazard of gold therapy?
A patient with seropositive rheumatoid developed a bullous eruption localised to the jewellery areas 12 hours after a test dose of sodium aurothiomalate (Myocrisin). Investigation showed that she was allergic to nickel rather than gold. Small quantities of nickel were found in the Myocrisin solution after a short contact with a metal needle, suggesting an explanation for the reaction.
D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D005260:Female; D006052:Gold Sodium Thiomalate / Q000008:administration & dosage*; D006801:Humans; D007273:Injections, Intramuscular / Q000295:instrumentation; D009532:Nickel / Q000009:adverse effects*
D006052:Gold Sodium Thiomalate; D009532:Nickel