The healing of autologous spongiosa and heterologous materials in the periodontal bone pocket. An animal experimental study.
In animal experiments with fully-grown beagle dogs we followed the healing of autologous spongiosa, collagen and binding gelatine by the use of polychrome sequential labelling. We found that when autologous spongiosa is transplanted into the periodontal intrabony pocket, the new material is fully remodelled after 6 weeks. When collagen is implanted, there is also a large amount of bone formed during this time. There was very little new bone formation after 6 weeks when binding gelatine was implanted.
D000166:Acridines / Q000627:therapeutic use*; D000818:Animals; D016025:Bone Transplantation; D003094:Collagen / Q000627:therapeutic use*; D004285:Dogs; D004338:Drug Combinations / Q000627:therapeutic use; D004975:Ethacridine / Q000627:therapeutic use*; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use*; D008856:Microscopy, Fluorescence; D008859:Microscopy, Polarization; D010514:Periodontal Pocket / Q000473:pathology / Q000601:surgery*; D010518:Periodontitis / Q000601:surgery*; D019736:Prostheses and Implants; D013997:Time Factors; D014945:Wound Healing
D000166:Acridines; D004338:Drug Combinations; C030215:Gelastypt M; D003094:Collagen; D004975:Ethacridine