Prognostic indicators of herpetic keratitis. Analysis of a five-year observation period after corneal ulceration.
Clinical features of 152 patients with herpetic keratitis after a five-year observation period were analyzed. When compared with dendritic ulceration, geographic ulcers that had been symptomatically present for a longer time were more likely to have been treated with a topical steroid and took longer to heal. After treatment of the corneal ulceration, 40% of the patients experienced a recurrent herpetic ulcer, 25% experienced disciform or irregular stromal keratouveitis, 5% experienced ocular hypertension, and 6% had a decrease in visual acuity caused by corneal scarring. Recurrent ulcerative herpetic keratitis occurred more frequently in men and in patients who entered the study with a history or previous herpetic ulceration.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D003320:Corneal Ulcer / Q000209:etiology / Q000628:therapy*; D003646:Debridement / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure; D007635:Keratitis, Dendritic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011897:Random Allocation; D012008:Recurrence; D014271:Trifluridine; D014740:Vidarabine / Q000627:therapeutic use; D014792:Visual Acuity
D000998:Antiviral Agents; D014740:Vidarabine; D014271:Trifluridine