title: The meiotic behavior of some single-cistron mutants in the zeste-white region of the Drosophila melanogaster X chromosome.
abstract: There are two dosage sensitive sites in the zeste-white region of the Drosophila melanogaster X chromosome that affect meiotic chromosome behavior. Single-cistron mutants at essential and female fertility loci in the two segments have been tested for meiotic effects similar to those of deficiencies. None of the mutants have detectable meiotic effects. A de novo search for meiotic mutants in the region has not uncovered any, but the results suggest that a deficiency for the zeste-white region would be useful for detecting meiotic mutants elsewhere in the genome. Tests for interactions between the deficiency and known meiotic mutants support this. Though tentative, these results suggest that non-essential regions need not be devoid of function.
mesh_terms: D000818:Animals; D004303:Dosage Compensation, Genetic; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005796:Genes; D005804:Genes, Lethal; D006580:Genetic Carrier Screening; D008540:Meiosis; D009154:Mutation; D010641:Phenotype; D012730:Sex Chromosomes; D014960:X Chromosome