Intracellular records from chronic alumina epileptogenic foci in the monkey.
Neuronal records from the primate alumina focus revealed synaptic potentials with bursts of action potentials occurring on depolarizing potentials. These depolarizing potentials were not synchronous with electrocorticographic epileptic patterns. The configuration of the membrane potential changes was consistent with a dendritic generator for epileptic bursts. It is proposed that the genesis of these depolarizing potentials is postsynaptic.
D000200:Action Potentials / Q000187:drug effects; D000537:Aluminum Oxide / Q000494:pharmacology; D000818:Animals; D003712:Dendrites; D004828:Epilepsies, Partial / Q000139:chemically induced / Q000503:physiopathology*; D007425:Intracellular Membranes / Q000187:drug effects / Q000502:physiology; D008253:Macaca mulatta; D009474:Neurons / Q000502:physiology*
D000537:Aluminum Oxide