Structural elucidation of adducts formed by ninhydrin with indoles and thiourea by 13C-NMR spectroscopy.
Condensation products were prepared by the reaction of ninhydrin with indole and 2,5-dimethylindole. The structures of these 1:1 adducts were assigned as 3-(2-hydroxy-2-indane-1,3-dionyl)indole and 3-(2-hydroxy-2-indane-1,3-dionyl)-2,5-dimethylindole, respectively, on the basis of spectral data including 13C-NMR evidence. 13C-NMR also was used to confirm the structure of a thiourea-ninhydrin adduct as a substituted thioindeno[1,2-d]imidazole-2,8-dione.
D002247:Carbon Isotopes; D055598:Chemical Phenomena; D002621:Chemistry; D003500:Cyclization; D007192:Indenes; D007211:Indoles; D009682:Magnetic Resonance Spectroscopy; D009555:Ninhydrin; D013890:Thiourea
D002247:Carbon Isotopes; D007192:Indenes; D007211:Indoles; D013890:Thiourea; D009555:Ninhydrin