title: [Aspects of the problem of regulator genes in the genetics of development].
abstract: The concept of gene-regulator in the genetics of prokaryotes and eukaryotes is considered. On the basis of numerous data, a conclusion is drawn on the presence of gene-controlled substances in eukaryotes which activate and suppress cell differentiation at many levels from transcription to posttranslation. It is proposed to define the gene-regulator in eukaryotes as a gene controlling the phenotypic expression (rather than activity only) of other genes at different levels of regulation.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006224:Cricetinae; D004331:Drosophila melanogaster; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D005057:Eukaryotic Cells / Q000201:enzymology / Q000648:ultrastructure; D005786:Gene Expression Regulation; D005796:Genes; D005809:Genes, Regulator; D006128:Growth; D006822:Hybrid Cells / Q000648:ultrastructure; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000235:genetics; D051379:Mice; D008815:Mice, Inbred Strains; D009154:Mutation; D010641:Phenotype
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Nekotorye aspekty problemy genov-reguliatorov v genetike razvitiia.