alpha-Glycerophosphate dehydrogenase activities in liver and brain mitochondria from neonatal rats treated with L-thyroxine.
Liver alpha-GPD undergoes a dramatic increase in newborn rats treated with large doses of L-thyroxine, indicating the elevated exposure of peripheral tissues to the hormone. In contrast, brain enzyme remains unchanged in the two mitochondria populations, free and synaptic.
D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000201:enzymology*; D005260:Female; D005993:Glycerolphosphate Dehydrogenase / Q000032:analysis*; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013974:Thyroxine / Q000494:pharmacology*
D005993:Glycerolphosphate Dehydrogenase; D013974:Thyroxine