Plasmid-determined tobramycin and gentamicin resistance in strains of Pseudomonas aeruginosa from two Sydney hospitals.
Strains of Pseudomonas aeruginosa resistant to gentamicin, tobramycin, streptomycin, and sulphonamide have been isolated from patients at two Sydney hospitals. The multiple resistance of all these strains was due to a transmissible plasmid. The significance of the identification of this plasmid, in this variety of strains and at two hospitals, for the treatment of Ps. aeruginosa infections is discussed.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001315:Australia; D003428:Cross Infection / Q000382:microbiology; D005839:Gentamicins / Q000494:pharmacology*; D006761:Hospitals; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000453:epidemiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000235:genetics; D011815:R Factors; D013307:Streptomycin / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology; D014031:Tobramycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D013449:Sulfonamides; D014031:Tobramycin; D013307:Streptomycin