Digestive tract of rats after hypokinesia and hypergravitation.
We found in rats submitted to a 7 days interval of hypokinesia a decreased glycoprotein content in salivary mucous glands, gastric and intestinal mucosa, an increased glycoprotein content and an increased content of leucine-aminopeptidase, acid and alkaline phosphatase. Similar changes were found after a short interval of centrifugation (+6 Gz, 10 min). These nonspecific responses were more accentuated if the hypergravitation was performed after 7 days of hypokinesia. We reproduced this way this events that occurred in space flight and deacceleration before landing.
D000054:Acceleration; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D003106:Colon / Q000378:metabolism; D004064:Digestive System / Q000378:metabolism*; D006023:Glycoproteins / Q000378:metabolism*; D006651:Histocytochemistry; D007413:Intestinal Mucosa / Q000378:metabolism; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D051381:Rats; D012149:Restraint, Physical
D006023:Glycoproteins; D000469:Alkaline Phosphatase; D007931:Leucyl Aminopeptidase