title: Regulatory properties of the pyruvate dehydrogenase complex of Pseudomonas aeruginosa.
abstract: The pyruvate dehydrogenase multienzyme complex of Pseudomonas aeruginosa was subjected to a steady-state kinetic analysis using the exponential model for a regulatory enzyme and a sensitive statistical fitting procedure. This showed that all the substrates, pyruvate, CoA and NAD+, exhibit cooperative kinetics towards the native multienzyme complex.
mesh_terms: D003065:Coenzyme A; D007700:Kinetics; D009243:NAD / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000201:enzymology*; D011768:Pyruvate Dehydrogenase Complex / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011773:Pyruvates; D013223:Statistics as Topic
chemical_list: D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D009243:NAD; D003065:Coenzyme A