[Intestinal lymphatic absorption of labelled oleic acid in the normal rat and rat treated with actidione-cycloheximide or acetoxycycloheximide].
Actidione-cycloheximide or acetoxycycloheximide treated and control Rats prepared with main mesenteric lymph duct cannulation were infused with a 90 mumol lipid emulsion composed of an equimolar mixture of monopalmitin, palmitic acid and 14C oleic acid and added with bile. In control Rats 75% of 14C oleic was recovered in lymph instead of 4,5% in treated rats. Although a low amount of lipids was concerned in this experiment, actidionecycloheximide and acetoxycycloheximide strongly inhibit intestinal absorption of oleic acid in lymph.
D000818:Animals; D003513:Cycloheximide / Q000031:analogs & derivatives* / Q000494:pharmacology; D007408:Intestinal Absorption / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000378:metabolism; D008196:Lymph / Q000378:metabolism*; D008297:Male; D009829:Oleic Acids / Q000378:metabolism*; D014176:Protein Biosynthesis; D051381:Rats
D009829:Oleic Acids; D003513:Cycloheximide; C004434:acetoxycycloheximide
Absorption intestinale par la voie lymphatique de l'acide oléique marqué chez le rat normal et le rat traité par l'actidione-cyclohéximide ou l'acétoxycyclohéximide.