title: [Antigens of Shigella dysenteriae serovars 3-7. IV. Immunochemical study of the exotoxin].
abstract: The exotoxins of Sh. dysenteriae, serovars 3 and 7, possess antigenic and serological properties and are characterized by the heterogeneous antigenic structure which distinctly differs from the structure of O-antigen in its immunochemical properties. These exotoxins consist of thermolabile and thermostable components. The thermolabile exotoxin fraction is a lethal toxin. The thermostable exotoxin fraction, obtained from the cultures of Sh. dysenteriae in the S-form, corresponds to O-antigen and forms an insignificant admixture in the concentrated exotoxins. The thermostable fraction of the exotoxins of S--R mutants differs from O-antigen by its serological specificity.
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis / Q000145:classification* / Q000276:immunology; D005098:Exotoxins / Q000032:analysis / Q000276:immunology*; D007120:Immunochemistry; D005779:Immunodiffusion; D007122:Immunoelectrophoresis / Q000379:methods; D011233:Precipitin Tests; D012703:Serotyping; D012762:Shigella dysenteriae / Q000145:classification* / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D005098:Exotoxins
vernacular_title: Antigeny Shigella dysenteriae serovarov 3-7. Soobshchenie IV. Immunokhimicheskoe izuchenie ékzotoksina.