Oro-facial lesions of tuberous sclerosis.
The occurrence of tuberous sclerosis among Indians has not been reported earlier. In the Ernakulam District, Kerala, in a kindred of 27, seven cases with oro-facial or facial lesions of tuberous sclerosis were observed. None of the individuals was mentally retarded, nor was there any history of systemic anomalies. The cases in this series possibly represent an incomplete form (Forme frustes) of the syndrome. The pedigree in the present material supports the autosomal dominant inheritance.
D000328:Adult; D000368:Aged; D002675:Child, Preschool; D005148:Facial Dermatoses / Q000473:pathology*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D010375:Pedigree; D012871:Skin Diseases / Q000473:pathology; D014402:Tuberous Sclerosis / Q000453:epidemiology / Q000235:genetics / Q000473:pathology*