title: Brain water and electrolytes in response to respiratory acidosis and brain edema in the mutant mouse, jimpy.
abstract: Compared to littermate controls, unstressed Jimpy mice have higher brain water, sodium, potassium and chloride contents and lower carbonic anhydrase activity. When stressed by CO2 to produce a respiratory acidosis or by injection of distilled water to produce brain edema, the Jimpy mouse brain has water and ionic responses essentially like those in controls.
mesh_terms: D000142:Acidosis, Respiratory / Q000378:metabolism*; D000818:Animals; D001834:Body Water / Q000032:analysis*; D001923:Brain Chemistry; D001929:Brain Edema / Q000378:metabolism*; D002256:Carbonic Anhydrases / Q000032:analysis; D004573:Electrolytes / Q000032:analysis*; D051379:Mice; D008816:Mice, Jimpy
chemical_list: D004573:Electrolytes; D002256:Carbonic Anhydrases