[Phosphorylase activity and glycogen content in cerebral and myocardium tissues in rats of different age].
The phosphorylase activity (EC 2.4.1.1) and the glycogen content were determined in the brain and myocardium of adult and old rats. In the cortex and while substance of great cerebral hemispheres, the phosphorylase a activity decreases and the phosphorylase b activity increases, while the total enzyme activity remains unchanged with aging. In the myocardium, the activity of phosphorylase a increases, while that of phophorylase b decreases against a background of an insignificant decrease in the total phosphorylase activity. During aging, the glycogen content decreases sharply in the myocardium, whereas in the cerebral tissue it remains unchanged. Age peculiarities of the adrenaline effect upon myocardial phosphorylase activity are presented.
D000375:Aging; D000818:Animals; D001921:Brain / Q000254:growth & development* / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism*; D006321:Heart / Q000254:growth & development*; D009206:Myocardium / Q000378:metabolism*; D010762:Phosphorylase a / Q000378:metabolism; D010763:Phosphorylase b / Q000378:metabolism; D006005:Phosphorylases / Q000378:metabolism*; D051381:Rats
D006003:Glycogen; D010762:Phosphorylase a; D010763:Phosphorylase b; D006005:Phosphorylases
Fosforilaznaia aktivnost' i soderzhanie glikogena v tkaniakh golovnogo mozga i miokarda krys raznogo vozrasta.