title: [Pathobiochemistry of mineral and trace elements. IV Iron concentration in whole blood and serum of pregnant women and newborn (author's transl)].
abstract: We determined the iron levels during the 10-40 week of pregnancy in 158 pregnant women to whom no iron supplements had been administered and who had normal pregnancies as well as toxic ones. We also determined the iron levels in 463 mothers during birth and those of their newborn. We obtained the following results. 1. In the course of pregnancy the iron level in the whole blood remains practically constant at the reduced level attained in the first few weeks until the 40th week, while a continuous depression of iron levels occurs in the serum. 2. Iron levels in whole blood are significantly elevated during a normal pregnancy in contrast to a pathological one, but the serum values stay practically identical in both groups. 3. The actual number of pregnancies (primi- or multipara) had no significant influence on the iron levels in either whole blood or serum in both normal or pathological pregnancies. 4. Blood group status had no influence on iron metabolism. 5. With a rhesus positive factor the whole blood level remains unchanged in the blood, but is significantly higher in the serum in comparison to a rhesus negative factor. 6. Comparison of apgar groups 5-7 with 8-10 showed significantly higher iron levels in mature neonates 8-10 only in the case of pathological pregnancy. 7. Sex of the newborn had no effect on the iron concentration in blood drawn from the umbilical cord. 8. Correlation between the iron values in whole blood and those in the serum are ascertainable in the different indications for toxic pregnancy. 9. Patients who had received an iron supplement therapy were excluded from the study.
mesh_terms: D001034:Apgar Score; D001789:Blood Group Antigens; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007501:Iron / Q000097:blood*; D008297:Male; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System; D012737:Sex Factors
chemical_list: D001789:Blood Group Antigens; D012204:Rh-Hr Blood-Group System; D007501:Iron
vernacular_title: Pathobiochemie von Mineral- und Spurenelementen., IV. Eisenkonzentration im Vollblut und Serum von Schwangeren und Neugeborenen.