Idiopathic inhibitor of factor VIII and its treatment by immunosuppression.
A patient with idiopathic inhibitor to factor VIII is reported. Treatment with cyclophosphamide and factor VIII (given simultaneously) produced a good clinical response with disappearance of the inhibitor.
D000906:Antibodies / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use*; D005169:Factor VIII / Q000276:immunology*; D005260:Female; D006467:Hemophilia A / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged
D000906:Antibodies; D003520:Cyclophosphamide; D005169:Factor VIII