Chromosome studies of patients on long-term lithium therapy for psychiatric disorders.
Chromosome studies, including sister chromatid exchange techniques, were performed on blood samples from 23 patients receiving long-term, continuous lithium therapy for psychiatric disorders. Nineteen healthy, age-matched individuals were used as controls. No increase in chromosome damage was detected, when samples from the lithium group were compared with the control group samples.
D000328:Adult; D002877:Chromosomes, Human / Q000187:drug effects*; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008134:Long-Term Care; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy; D008875:Middle Aged; D012854:Sister Chromatid Exchange / Q000187:drug effects
D008094:Lithium