title: Coagulation factors in women using oral contraceptives or intrauterine contraceptive devices immediately after abortion.
abstract: The changes in coagulation parameters were studied in 24 women who started using microdose combined oral contraceptives immediately after first-trimester abortion. Another 24 women who had an intrauterine contraceptive device inserted at the end of the abortion procedure were studied as control subjects. In pill users, a slightly increaed tendency toward hypercoagulability was observed 1 week after abortion in terms of elevated fibrinogen and Factor VIII as well as decreased antithrombin levels. Other studies have shown that the new follicle development after first-trimester abortion starts beyond the first week. It would therefore seem that by postponing oral contraceptive use until 1 week after abortion, no decrease in the effectiveness of contraception occurs and the possible risks of hypercoagulabilty during the postabortal period can be avoided.
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D000941:Antigens / Q000032:analysis; D000991:Antithrombins / Q000032:analysis; D001779:Blood Coagulation Factors / Q000032:analysis*; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage; D003278:Contraceptives, Oral, Hormonal; D004997:Ethinyl Estradiol / Q000008:administration & dosage*; D019304:Ethinyl Estradiol-Norgestrel Combination; D005169:Factor VIII / Q000032:analysis / Q000276:immunology; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007435:Intrauterine Devices, Copper; D009644:Norgestrel / Q000008:administration & dosage*; D011247:Pregnancy; D013997:Time Factors
chemical_list: D000941:Antigens; D000991:Antithrombins; D001779:Blood Coagulation Factors; D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination; D005169:Factor VIII; D005340:Fibrinogen