[Evaluation of the bactericidal activity of chiral alkylammonium salts derived from N-benzoyl-amino acids with Escherichia coli and Bacillus cereus. II. -- Adsorption mechanism and interpretation (author's transl)].
By testing the antibacterial activity of new long-chained alkylammonium salts with organic asymmetric anions (N-benzoyl-amino-acids) we have been able to precise the kind of interaction that would take place between the microorganisms and the two groups of the surfactant molecule. Evidence for anion participation to the bactericidal activity appeared through kind and configuration of the amino acid. A mechanism is proposed, that takes into account, hydrophobic and ionic interactions with cation and anion participation.
D000327:Adsorption; D000596:Amino Acids / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D001409:Bacillus cereus / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004926:Escherichia coli / Q000187:drug effects*; D008968:Molecular Conformation; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D000644:Quaternary Ammonium Compounds
Etude de l'activité bactéricide et bactériostatique de sels d'alkylamines chiraux dérivés d'acides aminés N-benzoylés sur Escherichia coli et Bacillus cereus. II. -- Mécanisme d'adsorption et essais d'interprétation.