Serological tests in the diagnosis of fungal urinary tract infection.
Fungus urine cultures were performed in 646 cases. In 50 we obtained a positive result. In 35 of these and in a control group of apparently healthy adults, we made serological studies using the following techniques: Immunodiffusion; counter immunoelectrophoresis, and immunofluorescence. 4 patients has positive precipitins against somatic and metabolic antigens. We obtained histological confirmation of deep candidiasis. In another 4 patients, the precipitins were positive against metabolic antigen only and further study failed to show deep candidiasis. In a further two cases we obtained positive titers using immunofluorescence; in 1 of these deep infection was confirmed. On no occasion in our study did the use of immunodiffusion and counter immunoelectrophoresis produce either false positive or false negative results against somatic antigen.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002175:Candida / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003378:Counterimmunoelectrophoresis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D005779:Immunodiffusion; D007223:Infant; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis*; D014552:Urinary Tract Infections / Q000175:diagnosis*