Leukocyte migration-inhibition responses of nonvaccinated and vaccinated heifers to experimental infection with Brucella abortus.
The leukocyte migration agarose technique was used to show the leukocyte migration-inhibition responses of nonvaccinated and vaccinated heifers to experimental infection with Brucella abortus. All heifers had increased leukocyte migration inhibition after exposure to B abortus. Nonvaccinated heifers which aborted had the highest responses. The responses of the vaccinated heifers were significantly (P less than 0.01) lower than those of nonvaccinated heifers. None of the vaccinated heifers aborted.
D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology; D002003:Brucella abortus / Q000276:immunology*; D002007:Brucellosis, Bovine / Q000175:diagnosis / Q000276:immunology*; D002417:Cattle / Q000276:immunology; D005260:Female; D007961:Leukocyte Migration-Inhibitory Factors / Q000276:immunology*; D008222:Lymphokines / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary*
D001428:Bacterial Vaccines; D007961:Leukocyte Migration-Inhibitory Factors; D008222:Lymphokines