title: Prostaglandins, antidiuretic hormone and renin angiotensin system.
abstract: Current knowledge on prostaglandin biosynthesis is reviewed, centering on how PGs participate in the regulation of vascular tone and the prevention of platelet deposition on endothelial surfaces. Discussion includes review of the vasoactivity of the PG endoperoxides, thromboxane, prostacyclin, and prostaglandin E2; prostaglandin-catabolizing enzymes; polyunsaturated fatty acid precursors; nutritional factors; antidiuretic hormone; and interrelations of PGs with the renin-angiotensin system.
mesh_terms: D000527:Alprostadil / Q000031:analogs & derivatives*; D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000096:biosynthesis; D002025:Bufonidae; D006224:Cricetinae; D004075:Diglycerides / Q000494:pharmacology; D004285:Dogs; D011464:Epoprostenol / Q000494:pharmacology; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D006911:Hydroxyprostaglandin Dehydrogenases / Q000096:biosynthesis; D009747:Nutritional Physiological Phenomena; D011453:Prostaglandins / Q000096:biosynthesis* / Q000494:pharmacology; D011458:Prostaglandins E / Q000096:biosynthesis; D011462:Prostaglandins G / Q000096:biosynthesis; D011463:Prostaglandins H / Q000096:biosynthesis; D011817:Rabbits; D012079:Renal Circulation; D012084:Renin-Angiotensin System / Q000187:drug effects*; D010738:Type C Phospholipases / Q000494:pharmacology; D014667:Vasopressins / Q000494:pharmacology*
chemical_list: D001095:Arachidonic Acids; D004075:Diglycerides; D005227:Fatty Acids; D011453:Prostaglandins; D011458:Prostaglandins E; D011462:Prostaglandins G; D011463:Prostaglandins H; D014667:Vasopressins; D016718:Arachidonic Acid; C022950:6-ketoprostaglandin E1; D011464:Epoprostenol; D006911:Hydroxyprostaglandin Dehydrogenases; D010738:Type C Phospholipases; D000527:Alprostadil