[Treatment of congenital chloride diarrhea with prostaglandin synthetase inhibitor (author's transl)].
In a patient with congenital chloride diarrhea, the hyperreninemia, hyperaldosteronism, hypokaliemia and hypokaliuria diminished during treatment with prostaglandin synthetase inhibitor. These findings suggest that probably prostaglandins stimulate renin-aldosterone system in congenital chloride diarrhea.
D000471:Alkalosis / Q000209:etiology; D002712:Chlorides / Q000378:metabolism*; D016861:Cyclooxygenase Inhibitors; D003968:Diarrhea, Infantile / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology; D007008:Hypokalemia / Q000209:etiology; D007223:Infant; D007660:Ketoprofen / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D010666:Phenylpropionates / Q000627:therapeutic use*; D012083:Renin / Q000097:blood
D002712:Chlorides; D016861:Cyclooxygenase Inhibitors; D010666:Phenylpropionates; D007660:Ketoprofen; D012083:Renin
Tratamiento de la clorodiarrea congénita con un inhibidor de las prostaglandinas.