[Analogies between "fraction P" with immunosuppressive properties in pregnant females and a protein fraction induced by estradiol treatment in the amphibian Salamandra salamandra L].
A "fraction P" analogue possessing immunosuppressive properties during pregnancy in the Salamandra, can be induced by treating males and females with oestradiol. Both fractions possess the same physiochemical characteristics, and equally react against a Rabbit immune serum anti "fraction P" of pregnant Salamandra. But the proteic fraction induced by hormonal treatment does immunosuppressive properties.
D000818:Animals; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D007106:Immune Sera; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000096:biosynthesis*; D008297:Male; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011817:Rabbits / Q000276:immunology; D012454:Salamandra; D012737:Sex Factors
D007106:Immune Sera; D007166:Immunosuppressive Agents; D004958:Estradiol
Analogies entre la "fraction P" à propriétés immunosuppressives chez les femelles gestantes, et une fraction protéique induite par un traitement à l'oestradiol, chez l'Amphibien Urodèle, Salamandra salamandra L.