[Polypeptides isolated from the gastric mucosa and their effect on pepsin biosynthesis by gastric glands].
It was found in experiments on 90 rats that polypeptides A, B and C (with a molecular mass of 2200-2800) isolated from the gastric mucosa have the ability to stimulate pepsin biosynthesis by the gastric glands. Application of the polypeptides did not result in the concurrent rise of proteolytic and milk-curdling activity. Pepsin and trypsin promoted the release from polypeptide B of low-molecular weight peptides which also stimulated pepsin biosynthesis.
D000818:Animals; D002384:Catalysis; D004063:Digestion; D005753:Gastric Mucosa / Q000032:analysis* / Q000378:metabolism; D008297:Male; D010434:Pepsin A / Q000096:biosynthesis* / Q000378:metabolism; D010455:Peptides / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D014357:Trypsin / Q000378:metabolism
D010455:Peptides; D014357:Trypsin; D010434:Pepsin A
Polipeptidy, vydelennye iz slizistoĭ obolochki zheludka, i ikh deĭstvie na biosintez pepsina zhelezami zheludka.