title: Effects of glycogen depletion and pedaling speed on "anaerobic threshold".
abstract: Nine male subjects performed continuous incremental exercise on a bicycle ergometer pedaling at 50 and 90 rpm in a normal glycogen state (NG) and at 50 rpm in a glycogen-depleted state (GD) to determine if alterations in pedaling frequency and muscle glycogen content would affect their "anaerobic thresholds." Ventilatory [T(vent)] and lactate [T(lac)] thresholds were identified as the points after which expired minute volume and blood lactate began to increase nonlinearly as a function of work rate. The GD protocol elicited a significant divergence between the two thresholds shifting the T(vent) to a lesser and the T(lac) to a greater work rate relative to the NG state. When the pedaling frequency was increased to 90 rpm in the NG condition, the T(lac) was shifted to a lesser work rate relative to the 50-rpm NG condition. A correlation of only 0.71 was obtained between subjects' T(vent) and T(lac). In subjects of less than 70 kg body wt, the T(lac) came at a work rate 400 kg.m.min-1 less than in subjects of greater than 80 kg body wt despite equivalent O2 uptake. The observation that the T(vent) and T(lac) could be manipulated independently of each other reveals limitations in using the T(vent) to estimate the so-called anaerobic threshold.
mesh_terms: D020155:3-Hydroxybutyric Acid; D000137:Acid-Base Imbalance; D000328:Adult; D000693:Anaerobiosis; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002245:Carbon Dioxide; D004056:Differential Threshold; D006003:Glycogen / Q000378:metabolism*; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008660:Metabolism; D010101:Oxygen Consumption; D005082:Physical Exertion; D012119:Respiration
chemical_list: D001786:Blood Glucose; D006885:Hydroxybutyrates; D007773:Lactates; D002245:Carbon Dioxide; D019344:Lactic Acid; D006003:Glycogen; D020155:3-Hydroxybutyric Acid