title: Lecithin treatment of cognitively impaired Parkinson's patients.
abstract: To test the effects of lecithin on cognitive deficits associated with Parkinson's disease, sixteen elderly and mentally-impaired outpatients with Parkinson's disease participated in a 9-week double-blind placebo-controlled study. Each patient took a daily dose of approximately 32 g of a commercial lecithin preparation containing 25% phosphatidylcholine, or an equivalent amount of powdered skim milk placebo. Marked clinical improvement was not observed, but some indications of a positive treatment effect were obtained on memory, cognition, and motility tests.
mesh_terms: D000368:Aged; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology; D004311:Double-Blind Method; D006801:Humans; D010300:Parkinson Disease / Q000150:complications / Q000188:drug therapy*; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D011897:Random Allocation
chemical_list: D010713:Phosphatidylcholines