Inhibition of arginase in sheep brain homogenates by some L-amino acids.
The effect of 16 L-amino acids on the activity levels of arginase in sheep brain homogenates was studied. The amino acids leucine, valine, lysine, and ornithine inhibited arginase activity significantly. The other amino acids tested did not show a significant influence on arginase activity. The inhibition was related to the carbon chain length of the amino acids.
D000596:Amino Acids / Q000494:pharmacology*; D000818:Animals; D001119:Arginase / Q000037:antagonists & inhibitors*; D001921:Brain / Q000201:enzymology*; D007930:Leucine / Q000494:pharmacology; D008239:Lysine / Q000494:pharmacology; D009952:Ornithine / Q000494:pharmacology; D012756:Sheep; D013329:Structure-Activity Relationship; D014633:Valine / Q000494:pharmacology
D000596:Amino Acids; D009952:Ornithine; D001119:Arginase; D007930:Leucine; D014633:Valine; D008239:Lysine