[Functional characteristics of phosphoenolpyruvate carboxylase in bacteria producing lysine].
Phosphoenol pyruvate carboxylase, or PEP-c (EC 4.1.1.31), was shown to be the only enzyme catalyzing anaplerotic synthesis of oxalacetic acid in Brevibacterium flavum synthesizing lysine. Acetyl-CoA is required for the operation of PEP-c in the strains. Changes in the activity of PEP-c did not entirely correlate with those of the citric acid cycle enzymes. Hence, PEP-c is involved not only in the citric acid cycle, but also in other functions of the cell. A correlation has been found between changes in the activity of PEP-c, the enzymes of the citric acid cycle and lysine production in B. flavum.
D000105:Acetyl Coenzyme A / Q000378:metabolism; D001951:Brevibacterium / Q000201:enzymology*; D002262:Carboxy-Lyases / Q000502:physiology*; D002952:Citric Acid Cycle; D008239:Lysine / Q000096:biosynthesis*; D010071:Oxaloacetates / Q000096:biosynthesis; D010730:Phosphoenolpyruvate Carboxylase / Q000502:physiology*
D010071:Oxaloacetates; D000105:Acetyl Coenzyme A; D002262:Carboxy-Lyases; D010730:Phosphoenolpyruvate Carboxylase; D008239:Lysine
Fosfoenolpiruvatkarboksilaza, osobennosti ee funktsionirovaniia u bakteriĭ, obrazuiushchikh lizin.