title: Bone changes in end-stage oxalosis.
abstract: Primary hyperoxaluria is a rare metabolic disease characterized by exaggerated production of oxalic acid. Clinically the disease is characterized by recurrent calcium nephrolithiasis, progressive renal failure, and early death in uremia. As the regular dialysis treatment may prolong survival, a new syndrome may develop. This is due to intense and continuous deposition of calcium oxalate crystals in soft and bone tissues. The radiologic aspects of oxalate deposition in four adult patients on chronic renal dialysis with histologic and clinical evidence of massive bone oxalosis are reported.
mesh_terms: D000293:Adolescent; D000328:Adult; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D001862:Bone Resorption; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology; D002129:Calcium Oxalate / Q000378:metabolism / Q000652:urine; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000378:metabolism; D007669:Kidney Calculi / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000378:metabolism; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D011859:Radiography; D013997:Time Factors; D014511:Uremia / Q000378:metabolism
chemical_list: D010281:Parathyroid Hormone; D002129:Calcium Oxalate