An inhibitor of the lipoxygenase and cyclooxygenase pathways of arachidonic acid, 5, 8, 11, 14-eicosatetraynoic acid, inhibits immunoglobulin E mediated antigen induced monkey asthma and skin reactions.
D015117:5,8,11,14-Eicosatetraynoic Acid / Q000494:pharmacology*; D000818:Animals; D001091:Arachidonate Lipoxygenases; D001249:Asthma / Q000503:physiopathology*; D016861:Cyclooxygenase Inhibitors; D003876:Dermatitis, Atopic / Q000503:physiopathology*; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D007073:Immunoglobulin E / Q000276:immunology; D007213:Indomethacin / Q000494:pharmacology; D016859:Lipoxygenase Inhibitors; D008253:Macaca mulatta
D016861:Cyclooxygenase Inhibitors; D005231:Fatty Acids, Unsaturated; D016859:Lipoxygenase Inhibitors; D015117:5,8,11,14-Eicosatetraynoic Acid; D007073:Immunoglobulin E; D001091:Arachidonate Lipoxygenases; D007213:Indomethacin