Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X chromosome. II. Genetical analysis.
The X chromosome region 9F12-10A7 (7 bands removed by Df(1)VL3) was saturated with lethal, semi-lethal, visible and male sterile mutations A total of 11 complementation groups were found. In the more narrow interval of Df()1)VL1 which removes 3 bands (10A1-2, 10A3, 10A4-5) 6 loci were localised. - The band 10A1-2 consists of a sereis of 5 different subunits: (i) silent DNA where no functions were found - at the distal edge of the band; (ii) and (iii) two genes: v and 1(1)BP4; (iv) silent DNA in middle of the band, (v) locus sev on the proximal edge of the band. About 70% of the band's DNA was found to be silent. - Using the set of chromosome rearrangements removing different parts of the band it was shown that these five sequences may function independently from each other.
D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005796:Genes; D005816:Genetic Complementation Test; D007248:Infertility, Male / Q000235:genetics; D008297:Male; D012730:Sex Chromosomes / Q000648:ultrastructure*; D014960:X Chromosome / Q000648:ultrastructure*