title: Complete metal ion requirement of influenza virus N1 neuraminidases. Brief report.
abstract: Influenza virus neuraminidases of the N1 serotype exhibit a complete dependence on Ca++ ions for activity. It is recommended that viral neuraminidase activity routinely be assessed in buffers containing 5 mM CaCl2.
mesh_terms: D002118:Calcium / Q000378:metabolism*; D004492:Edetic Acid / Q000494:pharmacology; D009980:Influenza A virus / Q000187:drug effects / Q000201:enzymology*; D009439:Neuraminidase / Q000378:metabolism*; D013045:Species Specificity; D014764:Viral Proteins / Q000378:metabolism*
chemical_list: D014764:Viral Proteins; D004492:Edetic Acid; D009439:Neuraminidase; D002118:Calcium