title: Bone scintigraphy for the detection and follow-up of hypertrophic osteoarthropathy.
abstract: A group of 100 patients with carcinoma of the lung underwent an examination for metastatic spread; evaluation of the bone scans taken at that time showed that 4 of these patients had the clinical and scintigraphic symptoms of hypertrophic osteoarthropathy. Roentgenological abnormalities were evident in 3 of these 4 cases. The diverse scintigraphic patterns characteristic of hypertrophic osteoarthropathy are discussed. Follow-up bone scans taken after initiation of therapy were used to investigate the changes in the scintigraphic patterns in 3 patients. Improvement was seen within 2 months. Clinical improvement preceded improvement on the scan; radiological improvement however, occurs later than that seen on the bone scan.
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D012968:Etidronic Acid; D005121:Extremities; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000000981:diagnostic imaging*; D011336:Probability; D011859:Radiography; D011877:Radionuclide Imaging; D013667:Technetium; D013997:Time Factors
chemical_list: D015609:Organotechnetium Compounds; C019561:technetium Tc 99m etidronate; D013667:Technetium; D012968:Etidronic Acid