Presence of an intermediate synthase form during the conversion of glycogen synthase D into synthase I in rat liver extract.
When synthase D was converted into synthase I in a liver extract, it progressed through a synthase form with activity characteristics that could not be explained by a mixture of the original synthase D and the final product, synthase I. This form was distinguished by an affinity for UDP-glucose, in the absence of glucose 6-phosphate, which was intermediate between those of the two known forms.
D000818:Animals; D004792:Enzyme Precursors / Q000378:metabolism*; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates / Q000378:metabolism; D006006:Glycogen Synthase / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014532:Uridine Diphosphate Glucose / Q000378:metabolism
D004792:Enzyme Precursors; D005958:Glucosephosphates; D019298:Glucose-6-Phosphate; D006006:Glycogen Synthase; D014532:Uridine Diphosphate Glucose