title: Chronic Chagas' disease: unimpaired delayed type hypersensitivity reactions in contrast with humoral suppression to typhoid vaccine.
abstract: Peripheral T and B cells were decreased in patients chronically infected with Trypanosome cruzi. The humoral response to Typhoid vaccine was suppressed in contrast with normal cutaneous delayed type hypersensitivity (DTH) reactions to Candida antigen, P.P.D., SK-SD, Vaccinia Virus antigen and DNCB. Complement and lg levels were between normal range and no immune complexes were detected by precipitation with polyethylene glycol.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology; D014355:Chagas Disease / Q000276:immunology*; D002908:Chronic Disease; D004137:Dinitrochlorobenzene / Q000276:immunology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D014436:Typhoid-Paratyphoid Vaccines / Q000276:immunology*
chemical_list: D000941:Antigens; D004137:Dinitrochlorobenzene; D014436:Typhoid-Paratyphoid Vaccines