Multiple antibody formation in a primigravida: anti-D, anti-C, anti-Kpb.
A case of primigravida in whom anti-C, anti-D, and anti-Kpb developed during the third trimester is described. Her first-born infant, delivered at 40 weeks' gestation, was mildly affected with hemolytic disease of the newborn and responded well to phototherapy. Her second-born infant, delivered at 36 weeks' gestation, had a positive direct antiglobulin test, but required no treatment. Clinical and laboratory aspects of both pregnancies are discussed.
D000328:Adult; D000917:Antibody Formation; D001789:Blood Group Antigens; D004899:Erythroblastosis, Fetal / Q000209:etiology*; D005260:Female; D005331:Fetomaternal Transfusion / Q000276:immunology; D006801:Humans; D007626:Kell Blood-Group System; D010298:Parity; D011247:Pregnancy; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D001789:Blood Group Antigens; D007626:Kell Blood-Group System; D012204:Rh-Hr Blood-Group System