title: [Indirect effects of synthetic LHRH on cervical mucus characteristics].
abstract: With the intention of establishing the indirect effect of synthetic LHRH on the qualities of cervical secretion, changes in the cervical mucus of 10 patients suffering from eugonadotropic and hypogonadotropic amenorrhoea were evaluated in a 5 day LHRH application in a daily dose of 100 micrograms i. m. Applying LHRH a significant increase of LH and FSH concentrations without evident differences in cervical mucus characteristics was observed. The quality of the cervical mucus was evaluated by arborization, spinnbarkeit, and the "burning phenomenon". In order to exclude to overall cervical unreactiveness, estrogens to LHRH were added in the course of the following five days. The cervical mucus characteristics had considerably improved without any evident change in FSH and LH concentrations. It is supposed that synthetic LHRH in a daily dose of 100 micrograms i. m. within five days does not affect ovarian steroid production in a way that could be reflected one change in the quality of the cervical mucus.
mesh_terms: D000328:Adult; D002582:Cervix Mucus / Q000187:drug effects*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D006728:Hormones / Q000494:pharmacology*; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism
chemical_list: D006728:Hormones; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Posredni uticaj sintetskog LHRH na karakteristike cervikalog sekreta.