New inhibitors of complement fixation.
A search for compounds that inhibit complement fixation revealed a number of new inhibitors. The presence of EDTA in the phosphate buffer containing complement and compound aided in the detection of compounds that inhibit complement fixation. Compounds were identified as inhibitors that previously could not be shown experimentally to inhibit complement fixation.
D000818:Animals; D003168:Complement Fixation Tests; D003169:Complement Inactivator Proteins; D004492:Edetic Acid / Q000494:pharmacology; D006168:Guinea Pigs; D006493:Heparin / Q000494:pharmacology; D011108:Polymers / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D003189:p-Methoxy-N-methylphenethylamine / Q000494:pharmacology
D003169:Complement Inactivator Proteins; D011108:Polymers; D013438:Sulfhydryl Compounds; D003189:p-Methoxy-N-methylphenethylamine; D006493:Heparin; D004492:Edetic Acid