title: Clinicohistopathologic correlations in xerophthalmic ulceration and necrosis.
abstract: Corneal tissue from five eyes of three children with active xerophthalmic keratopathy and stromal loss was studied histopathologically. Stromal dissolution was strikingly focal, sometimes occurring beneath an intact epithelium and often, though not always, accompanied by extensive inflammatory reaction and bacteria.
mesh_terms: D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000648:ultrastructure*; D003316:Corneal Diseases / Q000473:pathology*; D003320:Corneal Ulcer / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D011502:Protein-Energy Malnutrition / Q000150:complications; D014801:Vitamin A / Q000627:therapeutic use; D014802:Vitamin A Deficiency / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D014985:Xerophthalmia / Q000473:pathology*
chemical_list: D014801:Vitamin A