title: Work in progress: serial evaluation of tumor volume using computed tomography and contrast kinetics.
abstract: Computed tomography can be used to evaluate tumor volume changes after therapy. Pre- and posttreatment results are presented for nine human neoplasms. Volume changes are correlated with the behavior of intravenous diatrizoate contrast material. The five-minute diatrizoate distribution volume appears to be a potential contrast material marker for therapeutically induced tumor volume changes. Neoplasms decreasing in volume demonstrate a decrease in the diatrizoate distribution volume; those increasing in volume demonstrate an increase.
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000628:therapy; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine; D005069:Evaluation Studies as Topic; D006801:Humans; D007700:Kinetics; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000628:therapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D003973:Diatrizoate; D003974:Diatrizoate Meglumine