Mediastinal angiofollicular lymph node hyperplasia with systemic manifestations.
This case report concerns a 19-year-old girl with a mediastinal angiofollicular lymph node hyperplasia (Castleman tumour), with histological aspects of both hyalin vascular and plasma cell type. Systemic manifestations were also noticed. A lymphocytic infiltration of the bone marrow and a change in the lactic dehydrogenase iso-enzyme pattern with an increase of LDH3 were noted. After surgical removal of the mediastinal tumour complete recovery and normalisation of biological abnormalities occurred.
D000328:Adult; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008198:Lymph Nodes / Q000473:pathology*; D008477:Mediastinal Diseases / Q000473:pathology*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase