title: Alkaloid production by Claviceps sp. SD-58; involvement of phosphatase isozymes.
abstract: Simultaneous reduction in alkaloid yield and level of phosphatases by high concentrations of phosphate was observed in Claviceps sp. SD-58. Tryptophan-induced culture showed an increase in alkaloid yield and the level of phosphatases. Phosphate caused repression of both acid phosphatase (isoenzyme I) and alkaline phosphatase (isoenzymes III and V).
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000470:Alkaloids / Q000096:biosynthesis*; D002967:Claviceps / Q000378:metabolism*; D003470:Culture Media; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D010710:Phosphates / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology; D017680:Potassium Compounds; D014364:Tryptophan / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D003470:Culture Media; D007527:Isoenzymes; D010710:Phosphates; D017680:Potassium Compounds; D014364:Tryptophan; C013216:potassium phosphate; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D011188:Potassium