title: [Safety, reactogenicity and efficacy of pyoimmunogen in immunizing burn patients].
abstract: A study of pyoimmunogen, a new immunological preparation recommended for the prophylaxis and treatment of Pseudomonas aeruginosa infection, was carried out. The immunization of 20 patients with traumas caused by burns showed that the preparation induced no postvaccinal reactions and had no pathological effect on the hemogram and blood proteins, while normalizing temperature and producing the statistically significant increase of the specific antibody titer. The injection of pyoimmunogen improved the general state of the patients and the state of the burn wounds and reduced the period of hospitalization 1.5 times.
mesh_terms: D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D002056:Burns / Q000276:immunology*; D002986:Clinical Trials as Topic; D006388:Hemagglutinins / Q000032:analysis; D006801:Humans; D007114:Immunization; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000276:immunology / Q000517:prevention & control*; D011550:Pseudomonas aeruginosa / Q000276:immunology; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D006388:Hemagglutinins
vernacular_title: Izuchenie bezvrednosti, reaktogennosti i éffektivnosti pioimmunogena pri immunizatsii ozhogovykh bol'nykh.