title: Hypothermia induced in mice by injection of venom sac extract of hornets (Vespa orientalis, vespinae: hymenoptera).
abstract: Intraperitoneal injection into naive and immunized albino mice of Oriental hornet venom sac aqueous extract induces within 3 h an 8-10 degrees C and 3-4 degrees C drop in body temperature, respectively. The fall in temperature is dose-dependent. The responsible fraction(s) in the venom is of high molecular weight.
mesh_terms: D000818:Animals; D001514:Bee Venoms / Q000494:pharmacology*; D001831:Body Temperature / Q000187:drug effects; D003956:Dialysis; D007035:Hypothermia / Q000139:chemically induced*; D007114:Immunization; D007700:Kinetics; D008297:Male; D051379:Mice; D014862:Wasp Venoms / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D001514:Bee Venoms; D014862:Wasp Venoms