title: Variations in oxygen consumption and carbon dioxide production during parenteral nutrition.
abstract: To verify that variations caused by total parenteral nutrition (TPN) in O2 intake (VO2) and CO2 output (VCO2) can affect respiratory function of non-hypercatabolic patients, we studied 18 patients in two groups; group I (control): eight patients receiving 75-100 g glucose/24 h, and group II: ten patients fed intravenously on 13.6 g N2 and approximately 2,800 kcal/24 h given as a) 62% glucose + 38% fats (TPN-G + F) and b) 100% glucose (TPN-G). VO2, VCO2, respiratory quotient (RQ) and minute ventilation (VE) were measured in all patients. We found that VCO2 was 27% higher in intravenously fed patients (p less than 0.01 and p less than 0.02). Similarly, VE was 26% higher in intravenously fed patients (p less than 0.001 and p less than 0.02). Comparison of TPN-G + F and TPN-G results showed no differences in VCO2; by contrast, VO2 was 21% less during TPN-G (p less than 0.01).
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide; D005223:Fats / Q000008:administration & dosage; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D010288:Parenteral Nutrition; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D012119:Respiration
chemical_list: D005223:Fats; D002245:Carbon Dioxide; D005947:Glucose