Correlation of level and duration of Streptococcus mutans infection with incidence of dental caries.
The caries incidence at various levels of Streptococcus mutans infection was analyzed in a control group and a test group. In the control group, the incidence of caries and the duration of S. mutans infection were significantly correlated. In the test group, the S. mutans infection was suppressed by antimicrobial measures when the number of S. mutans exceeded 250 X 10(3) CFU per ml of saliva. The results illustrate that the level and duration of the S. mutans infection are strongly correlated to the incidence of caries. The findings support the concept of S. mutans as a key cariogenic microorganism and illustrate the value of antimicrobial treatment in the prevention of caries.
D000293:Adolescent; D002710:Chlorhexidine / Q000627:therapeutic use; D003731:Dental Caries / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D012463:Saliva / Q000382:microbiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013295:Streptococcus mutans / Q000302:isolation & purification*; D013997:Time Factors
D002710:Chlorhexidine