The resistance of glyoxylic acid induced catecholamine fluorescence to sodium borohydride reduction.
The borohydride reduction of glyoxylic acid induced fluorescence in noradrenergic and DOPA-minergic nervous structures and in amines in model experiments was studied. Both DOPAmine and noradrenaline fluorescences were resistant to borohydride reduction differing thus from the formaldehyde-induced fluorescence. Thus when the specificity of glyoxylic acid induced fluorescence is in doubt, other tests than borohydride reduction of the fluorescence must be employed.
D000818:Animals; D001894:Borohydrides / Q000494:pharmacology*; D002395:Catecholamines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D005557:Formaldehyde / Q000494:pharmacology; D006038:Glyoxylates / Q000494:pharmacology*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains
D001894:Borohydrides; D002395:Catecholamines; D006038:Glyoxylates; D005557:Formaldehyde; C025364:sodium borohydride; D004298:Dopamine; D009638:Norepinephrine