Disseminated malignant phaeochromocytoma: localisation with iodine-131-labelled meta-iodobenzylguanidine.
Meta-iodobenzylguanidine, a guanethidine analogue, is a newly synthesised substance capable of imaging the adrenal medulla. In a woman in whom phaeochromocytoma has been diagnosed iodine-131-labelled metaiodobenzylguanidine was given intravenously; gamma-camera images showed bilateral adrenal tumours and uptake corresponding to bone and liver metastases. 131I-meta-iodobenzylguanidine is effective in localising phaeochromocytomas, and the technique is safe, specific, and non-invasive.
D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000556:secondary; D005260:Female; D006146:Guanidines; D006801:Humans; D007457:Iodine Radioisotopes; D007680:Kidney Neoplasms / Q000556:secondary; D008875:Middle Aged; D010673:Pheochromocytoma / Q000000981:diagnostic imaging* / Q000556:secondary; D011877:Radionuclide Imaging
D006146:Guanidines; D007457:Iodine Radioisotopes; D019797:3-Iodobenzylguanidine