[Importance of cross reactions in evaluating the serological diagnosis of human brucellosis. II. Examination of brucellosis patients by the passive hemagglutination reaction using homologous and heterologous erythrocyte diagnostica].
The study of 270 serum samples obtained from chronic brucellosis patients in the passive hemagglutination test have revealed that in the presence of specific brucellosis hemagglutinins cross reactions with Yersinia antigen may occur. This phenomenon is probably due to the presence of common antigenic determinants in the lipopolysaccharide fractions of Brucella abortus 99 and Yersinia enterocollitica 09. The passive hemagglutination test has revealed that 2-mercaptoethanol-sensitive antibodies (IgM) to both homologous and heterologous antigens are mainly present in chronic brucellosis patients.
D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000276:immunology; D002003:Brucella abortus / Q000276:immunology; D002006:Brucellosis / Q000175:diagnosis*; D002908:Chronic Disease; D003429:Cross Reactions; D004912:Erythrocytes / Q000276:immunology*; D006386:Hemagglutination Tests / Q000379:methods; D006801:Humans; D015007:Yersinia / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Znachenie perekrestnykh reaksiĭ v otsenke serologicheskoĭ diagnostiki brutselleza u liudeĭ. Soobshchenie II. Obsledovanie bol'nykh brutsellezom pri pomoshchi reaktsii passivnoĭ gemaggliutinatsii s ispol'zovanium gomologichnykh i geterologichnykh éritrotsitarnykh diagnostikumov.