Development of sleep-waking temporal sequencing in infants at risk for the Sudden Infant Death Syndrome.
The periodic organization of waking, quiet sleep, and active sleep was studied in control infants and siblings of victims of the Sudden Infant Death Syndrome. Spectral estimates of all-night binary state time series recorded at 1 week and 1, 2, 3, 4, and 6 months of age revealed disturbed patterns of sleep states, especially in active sleep, from as early as the first week of life. These disruptions continued until at least 6 months of age. These data support the contention that the temporal patterning of sleep state can be used as an important neurologic marker for development.
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012306:Risk; D012894:Sleep Stages / Q000502:physiology*; D013398:Sudden Infant Death / Q000503:physiopathology*; D013997:Time Factors