title: Involvement of tryptophan residues in colchicine binding and the assembly of tubulin.
mesh_terms: D015077:2-Hydroxy-5-nitrobenzyl Bromide; D000818:Animals; D001921:Brain / Q000378:metabolism; D003078:Colchicine / Q000378:metabolism*; D066298:In Vitro Techniques; D008870:Microtubules / Q000378:metabolism; D011487:Protein Conformation; D012756:Sheep; D013329:Structure-Activity Relationship; D014364:Tryptophan; D014404:Tubulin / Q000378:metabolism*
chemical_list: D014404:Tubulin; D015077:2-Hydroxy-5-nitrobenzyl Bromide; D014364:Tryptophan; D003078:Colchicine