title: 4-Aminopyridine and fiber potentials in rat and human hippocampal slices.
abstract: Compound fiber action potentials of stratum radiatum afferents in slices from human and rat hippocampus are shown to be prolonged by 4-aminopyridine (4-AP). This action can explain the enormous increase in synaptic transmitter release caused by 4-AP.
mesh_terms: D015761:4-Aminopyridine; D000200:Action Potentials / Q000187:drug effects; D000631:Aminopyridines / Q000494:pharmacology*; D000818:Animals; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D051381:Rats; D013569:Synapses / Q000502:physiology
chemical_list: D000631:Aminopyridines; D015761:4-Aminopyridine