The effect of striatal lesions in the chick on haloperidol-potentiated tonic immobility.
The potentiating effects of haloperidol on tonic immobility in chickens were reduced in birds given bilateral injections of kainic acid into the paleostriatum. Aspiration of tissue above the lamina medullaris dorsalis, which includes the neostriatum and hyperstriatum, had no significant effect on haloperidol-potentiated tonic immobility. The results support the suggestion that the paleostriatum of birds is homologous to the basal ganglia of mammals.
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D002645:Chickens; D003342:Corpus Striatum / Q000502:physiology*; D006220:Haloperidol / Q000494:pharmacology*; D007608:Kainic Acid / Q000494:pharmacology; D008297:Male; D009043:Motor Activity / Q000187:drug effects* / Q000502:physiology
D006220:Haloperidol; D007608:Kainic Acid