title: Adherence to human monocytes of red cells from autoimmune haemolytic anaemia and red cells sensitized with alloantibodies.
abstract: Red cells sensitized with autoantibodies are able to adhere in vitro to autologous monocytes and monocytes from healthy individuals. A direct relationship between the degree of sensitization and the percentage of rosettes was not observed, while such a correlation was found if red cells sensitized with anti-Rh alloantibodies were used. Sometimes the adherence of red cell from AIHA was observed although the sensitization was weaker than that of the control erythrocytes sensitized with anti-CD serum which did adhere to monocytes. In patients with AIHA some relation was found between the adherence assay, haemolysis in vivo and treatment with prednisone.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000276:immunology*; D001323:Autoantibodies; D004912:Erythrocytes / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007074:Immunoglobulin G / Q000145:classification; D007518:Isoantibodies; D009000:Monocytes / Q000378:metabolism*; D012204:Rh-Hr Blood-Group System / Q000276:immunology; D012397:Rosette Formation
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System