Possible chemotaxis of human monocytes by N-acetylmuramyl-L-alanyl-D-isoglutamine.
N-Acetylmuramyl-l-alanyl-d-isoglutamine (MDP) induced the chemotaxis of human blood monocytes without mediation of serum complement. Specificity (dependency on chemical structure) of the chemotactic activity of MDP was evidenced by a negligible activity of analogs lacking most of the immunomodulating activities of MDP.
D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000494:pharmacology*; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D006801:Humans; D009000:Monocytes / Q000187:drug effects / Q000276:immunology*
D000119:Acetylmuramyl-Alanyl-Isoglutamine