title: Prostatic and laryngeal malignancies: common or uncommon multiple occurrence?
abstract: The presence of multiple primary malignancies involving the head and neck has been well documented. The majority of second primaries appear within the respiratory system. Few reports exist describing multiple primary malignancies involving the larynx and the prostate. This paper reports on four cases of primary laryngeal and prostatic neoplasms. Physical findings and laboratory work-up necessary for diagnosis of these lesions are reviewed. The dilemma of the proper therapeutic course based on the histological grading and pathological staging is presented. Suggestions for treatment based on the prognosis of the disease that is present are offered.
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D011471:Prostatic Neoplasms / Q000175:diagnosis*