Phagocytosis and killing of Francisella tularensis by human polymorphonuclear leukocytes.
Bacteria of a wild strain of Francisella tularensis were less efficiently killed by human polymorphonuclear leukocytes than were bacteria of an attenuated strain. This finding was explained to some extent by a less efficient phagocytosis, but bacteria of the wild strain also seemed to be more resistant to killing after ingestion.
D001769:Blood; D003176:Complement C3 / Q000502:physiology; D003182:Complement C5 / Q000502:physiology; D005604:Francisella tularensis / Q000276:immunology* / Q000472:pathogenicity; D006801:Humans; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology; D010587:Phagocytosis
D003176:Complement C3; D003182:Complement C5