title: [Participation of histamine and cyclic nucleotides in the regulation of gastric secretion in experimental thyrotoxicosis].
abstract: Experiments on 48 Wistar rats evidence that in early times of hyperthyroidism, the action of thyroxine on parietal cells is mediated by histamine and cAMP, while in prolonged hyperthyroidism, its action on parietal cells refractory to endogenous histamine and cAMP is found to be unmediated and direct.
mesh_terms: D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism*; D006632:Histamine / Q000502:physiology*; D006980:Hyperthyroidism / Q000139:chemically induced / Q000503:physiopathology*; D008297:Male; D009712:Nucleotides, Cyclic / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013974:Thyroxine / Q000494:pharmacology
chemical_list: D009712:Nucleotides, Cyclic; D006632:Histamine; D013974:Thyroxine
vernacular_title: Uchastie gistamina i tsiklicheskikh nukletotidov v reguliatsii zheludochnoĭ sekretsii pri éksperimental'nom tireotoksikoze.