Recurrent carcinoma of the larynx and the hypopharynx.
From a group of 765 patients treated primarily at Barnes Hospital (St Louis) for epidermoid carcinoma of the larynx and the hypopharynx, 199 cases of recurrent disease were identified. To define this group of recurrent carcinoma, the following study parameters were selected: initial site of lesion, initial pathologic condition, initial therapy, complications of therapy, site of recurrence, secondary treatment, and end results. Cause of death is detailed as a result of primary cancer (local, neck, distant, and mixed), complications of treatment, secondary cancer, or intercurrent disease. An attempt is made to correlate the data to understand this anomaly and its responses to therapy better.
D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D010610:Pharyngeal Neoplasms / Q000473:pathology*; D011379:Prognosis