title: Activation of prophenol oxidase in the liver fluke Fasciola gigantica Cobbold.
abstract: Activation of prophenol oxidase of Fasciola gigantica has been demonstrated using biochemical and electrophoretic techniques. Based on the difference in the electrophoretic pattern of the proenzyme and activated enzyme, a probable mechanism of activation of the prophenol oxidase is suggested. A role for Mehlis' gland in the activation process is suggested. The significance of the results is discussed in the light of related studies in insects.
mesh_terms: D000818:Animals; D004156:Catechol Oxidase / Q000378:metabolism*; D002712:Chlorides; D004789:Enzyme Activation / Q000187:drug effects; D004792:Enzyme Precursors / Q000378:metabolism*; D005088:Exocrine Glands; D005209:Fasciola / Q000201:enzymology*; D008345:Manganese / Q000494:pharmacology; D017895:Manganese Compounds; D019301:Oleic Acid; D009829:Oleic Acids / Q000494:pharmacology; D014020:Tissue Extracts / Q000494:pharmacology
chemical_list: D002712:Chlorides; D004792:Enzyme Precursors; D017895:Manganese Compounds; D009829:Oleic Acids; D014020:Tissue Extracts; D019301:Oleic Acid; C013173:osteum; D008345:Manganese; D004156:Catechol Oxidase; C025340:manganese chloride