title: Presence of antigen sensitized leukocytes in carp (Cyprinus carpio L) following bath immunization against Flexibacter columnaris.
abstract: Bath immunization of carp (Cyprinus carpio L) resulted in protection of fish at natural challenge. Stimulation of leukocytes derived from thymus, spleen, anterior kidney and mid-kidney of fish immunized with Flexibacter columnaris bacterin revealed the presence of antigen sensitized cells in all lymphoid tissues except the anterior kidney. After 28 days a response was obtained in thymus and spleen leukocyte cultures.
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001424:Bacterial Infections / Q000276:immunology / Q000662:veterinary; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002347:Carps; D005260:Female; D005393:Fish Diseases / Q000276:immunology*; D007114:Immunization / Q000379:methods / Q000662:veterinary*; D007668:Kidney / Q000166:cytology; D007962:Leukocytes / Q000276:immunology*; D008213:Lymphocyte Activation; D008297:Male; D008934:Mitogens / Q000494:pharmacology; D009231:Myxococcales / Q000276:immunology*; D013154:Spleen / Q000166:cytology; D013950:Thymus Gland / Q000166:cytology
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D008934:Mitogens