Unusual metastatic pattern in testicular malignant teratoma.
A 25-year-old man presented with a malignant teratoma of the right testicle. After orchidectomy, the results of the surgical staging procedure were negative. Although pulmonary metastasis did not occur, massive bone marrow involvement with a bleeding tendency and hypercalcemic nephropathy developed. The response to chemotherapy was excellent, but after the attainment of a complete remission the patient developed carcinomatous leptomeningitis, which was confirmed at autopsy as cause of death.
D000328:Adult; D001855:Bone Marrow Diseases / Q000473:pathology; D001856:Bone Marrow Examination; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*