Activation of prophenol oxidase in the liver fluke Fasciola gigantica Cobbold.
Activation of prophenol oxidase of Fasciola gigantica has been demonstrated using biochemical and electrophoretic techniques. Based on the difference in the electrophoretic pattern of the proenzyme and activated enzyme, a probable mechanism of activation of the prophenol oxidase is suggested. A role for Mehlis' gland in the activation process is suggested. The significance of the results is discussed in the light of related studies in insects.
D000818:Animals; D004156:Catechol Oxidase / Q000378:metabolism*; D002712:Chlorides; D004789:Enzyme Activation / Q000187:drug effects; D004792:Enzyme Precursors / Q000378:metabolism*; D005088:Exocrine Glands; D005209:Fasciola / Q000201:enzymology*; D008345:Manganese / Q000494:pharmacology; D017895:Manganese Compounds; D019301:Oleic Acid; D009829:Oleic Acids / Q000494:pharmacology; D014020:Tissue Extracts / Q000494:pharmacology
D002712:Chlorides; D004792:Enzyme Precursors; D017895:Manganese Compounds; D009829:Oleic Acids; D014020:Tissue Extracts; D019301:Oleic Acid; C013173:osteum; D008345:Manganese; D004156:Catechol Oxidase; C025340:manganese chloride