title: [Clinical use of latex tests. II. Evaluation of latex tests in C-reactive protein determination].
abstract: We compared the most reliable and practical laboratory methods for the quantitative determination of serum C-reactive protein that is polistyrene latex particles together with purified anti-C-reactive protein rabbit globulin, the precipitation test using anti-C-reactive protein serum and finally, radial immunodiffusion on agar-gel plates. We examined 163 serum specimens from ambulatory patients and from various hospitalized patients in Istituti Clinici di Perfezionamento of Milan (Italy). All the methods tested showed a good qualitative discrimination for serum C-reactive protein presence or absence at pathological levels. We also compared the two latex methods. In conclusion, radial immunodiffusion confirmed to be the best method for accurate C-reactive protein dosage during inflammatory and degenerative processes.
mesh_terms: D002097:C-Reactive Protein / Q000032:analysis*; D011232:Chemical Precipitation / Q000379:methods; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D007841:Latex Fixation Tests; D008297:Male
chemical_list: D002097:C-Reactive Protein
vernacular_title: L'impiego clinico dei tests al lattice. II. Valutazione dei metodi al lattice per la determinazione della proteina C reattiva (PCR).