Evaluation of Prl secretion in elderly subjects.
Prl secretion was evaluated in 76 elderly patients (71-86z years) without endocrine disorders (38 men and 38 women) in basal conditions, after TRH, sulpiride and levodopa administration and during a 24 h period. An impaired Prl response to the administered drugs was found in the elderly women but not in the men. On the contrary, normal sleep-related serum Prl changes were found in the majority of the subjects studied. These results suggest that the pituitary gland can maintain a good Prl secretory pattern in the elderly.
D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007980:Levodopa / Q000494:pharmacology; D008297:Male; D011388:Prolactin / Q000378:metabolism*; D012737:Sex Factors; D013469:Sulpiride / Q000494:pharmacology; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D013997:Time Factors
D007980:Levodopa; D013973:Thyrotropin-Releasing Hormone; D013469:Sulpiride; D011388:Prolactin