title: Effect of mechanical load in wound healing.
abstract: This study was designed to investigate the effect of sequentially increasing mechanical load on healing incisions. Full-thickness incisions were made on the back of a young domestic pig. During the period of fibroplasia, one of the incisions was mechanically loaded with a subcutaneous tissue expander. Mechanical and histological evaluations of mechanically loaded and control incision areas indicated that the mechanical stress encouraged healing and remodeling of dermal tissue.
mesh_terms: D000818:Animals; D062109:Dermatologic Surgical Procedures; D008855:Microscopy, Electron, Scanning; D012867:Skin / Q000033:anatomy & histology / Q000648:ultrastructure; D013314:Stress, Mechanical; D013552:Swine; D014945:Wound Healing