Cellular damage and recovery of the early developing mouse eye following low dose irradiation. II. X-rays on day 9 of gestation.
Mouse embryos on day 9 of gestation were exposed in utero to 90 rad X-rays. At different time intervals after treatment the eye primordia were examined for cell death. The irradiation caused an altered necrosis pattern compared with day 8, and massive cell killing during a limited time period. The rapid recovery from the pronounced damage points to a high restitution efficiency of the involved tissue.
D000818:Animals; D002470:Cell Survival; D004622:Embryo, Mammalian / Q000528:radiation effects*; D005123:Eye / Q000196:embryology* / Q000528:radiation effects; D005260:Female; D005865:Gestational Age; D007700:Kinetics; D051379:Mice; D009799:Ocular Physiological Phenomena; D011247:Pregnancy; D012038:Regeneration