title: Effects of limb tourniquet ischemia on local and systemic acid-base and blood gases of cattle.
abstract: Effects of forelimb tourniquet ischemia of 90 minute duration were investigated in six bulls aged two to three years. Studies were also conducted up to 150 minutes after release of the tourniquet. Parameters investigated were pH, PCO2, PO2, oxygen saturation and HCO3. In systemic circulation no variations in different parameters were observed during 90 minutes of ischemia. However, significant increase in arterial and venous pH were observed after 30 and 45 minutes of the release of tourniquet, respectively. These increases were accompanied by an increase in HCO3. In the affected limb, ischemia resulted in severe acidosis with a significant increase in PCO2 and a nonsignificant decrease of HCO3. There was a significant fall in PO2 and oxygen saturation. After release of the tourniquet, limb venous pH increased significantly due to a significant fall in PCO2 and a nonsignificant increase in HCO3. A significant increase in the limb venous PO2 and oxygen saturation post tourniquet was observed up to the end of the experiments. There was evidence of very poor oxygen exchange and utilization up to 150 minutes after release of the tourniquet. These results demonstrated that tourniquet ischemia of 90 minutes duration of the limb of cattle may not be safe.
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001639:Bicarbonates / Q000097:blood; D002245:Carbon Dioxide / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism*; D005552:Forelimb / Q000098:blood supply*; D006863:Hydrogen-Ion Concentration; D007511:Ischemia / Q000209:etiology / Q000378:metabolism / Q000662:veterinary*; D008297:Male; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D014111:Tourniquets / Q000009:adverse effects / Q000662:veterinary*
chemical_list: D001639:Bicarbonates; D002245:Carbon Dioxide; D010100:Oxygen