Acyclovir treatment in stromal herpetic keratitis.
Twenty-five patients with long standing deep stromal herpetic keratitis and iritis were treated with acyclovir (3%) ointment and corticosteroids. All patients healed in about two to four weeks, independent of the duration of the keratitis before acyclovir treatment and independent of the antiviral medication given previously. Recurrences could not be prevented by acyclovir treatment. No serious side effects of acyclovir were noted.
D000212:Acyclovir / Q000627:therapeutic use*; D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D006801:Humans; D007500:Iritis / Q000188:drug therapy*; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D012008:Recurrence; D014792:Visual Acuity
D000305:Adrenal Cortex Hormones; D000212:Acyclovir