[Bronchospasm induction by mediators of antigen-specific stimulated lymphoid cells].
The action of lymphokines, soluble mediators of cell-mediated immunity was studied on isolated lungs of guinea-pigs. Antigen-specific antigens were shown to have bronchospastic activity as regards sensitized and nonsensitized lungs. The bronchospastic effect is not mediated by histamine or by other chemical bronchoconstrictors, and is not linked with activity of leukocyte migration inhibition factor.
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001980:Bronchi / Q000503:physiopathology; D001986:Bronchial Spasm / Q000276:immunology*; D002002:Brucella / Q000276:immunology; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D008222:Lymphokines / Q000276:immunology* / Q000502:physiology; D009130:Muscle, Smooth / Q000503:physiopathology; D013211:Staphylococcus aureus / Q000276:immunology
D000942:Antigens, Bacterial; D008222:Lymphokines
Induktsiia bronkhospazma mediatorami antigenospetsificheski stimulirovannykh limfoidnykh kletok.