title: Elastic and precursor fibres in the normal human eye.
abstract: Completely formed elastic fibres consist of a core of amorphous elastin within a mantle of microfibrils. The fibrillar component may occur as isolated bundles (oxytalan) or may be randomly intermingled with variable amounts of elastin (elaunin). The distribution of both mature elastic and incomplete oxytalan and elaunin fibres in the different parts of 53 human eyes from foetal life to old age is described, as evaluated by light microscopy of histochemical preparations. In general elastic tissue was most evident in the collagenous structures save the adult cornea in which incomplete elastic fibres occur rarely and then late in life. Precursor forms predominate in early childhood and show a limited and slow capacity for maturation. The suspensory zonular fibres of the lens appear to be composed largely of oxytalan throughout life. There is also evidence that corneal epithelium and endothelium, irideal smooth muscle and, less certainly, retinal pigment epithelium can synthesise the fibrillar component, although not elastin, of elastic tissue.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002648:Child; D002675:Child, Preschool; D003228:Conjunctiva / Q000033:anatomy & histology; D003315:Cornea / Q000033:anatomy & histology; D004547:Elastic Tissue / Q000033:anatomy & histology*; D005123:Eye / Q000033:anatomy & histology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007908:Lens, Crystalline / Q000033:anatomy & histology; D008875:Middle Aged; D012590:Sclera / Q000033:anatomy & histology; D014602:Uvea / Q000033:anatomy & histology