[Adhesivity and chemotaxis of leukocytes during infusion of Intralipid].
The effect of an intravenously administered lipid emulsion (Intralipid) on granulocyte functions has been studied. The study has been carried out in 20 healthy individuals, divided into two groups: 10 individuals have been infused with Intralipid 10% i.v.; the other 10 individuals (controls) have not been infused with any pharmacologically active solution. In all the subjects the following parameters have been studied: blood granulocyte count, granulocyte adherence and leucocyte chemotaxis. The results showed a transient fall of granulocyte adherence during the intralipid infusion; no alterations of granulocyte count and leucocyte chemotaxis were found.
D000268:Adhesiveness; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005217:Fat Emulsions, Intravenous; D006098:Granulocytes / Q000187:drug effects; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D008055:Lipids / Q000008:administration & dosage / Q000494:pharmacology*; D010289:Parenteral Nutrition, Total
D005217:Fat Emulsions, Intravenous; D008055:Lipids
Studio della adesivita e chemiotassi leucocitaria durante infusione di Intralipid.