Hypermagnesemic periodic paralysis: treatment with digitalis and lithium carbonate.
An 18-year-old man suffering from a hereditary hyperkalemic periodic paralysis showed, in addition, a hypermagnesemic periodic paralysis with a 2.5-fold increase in serum magnesium level. All other serum electrolyte levels were normal. The hypermagnesemic periodic paralysis seems to have been caused by a disturbance of the renal tubular system. Thus, magnesium-stimulated paralysis was prevented by treatment with lithium carbonate and digitalis, which blocked the active ion transport.
D000293:Adolescent; D004077:Digoxin / Q000031:analogs & derivatives*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008274:Magnesium / Q000097:blood; D008297:Male; D008520:Medigoxin / Q000627:therapeutic use*; D010245:Paralyses, Familial Periodic / Q000097:blood / Q000188:drug therapy*
D016651:Lithium Carbonate; D004077:Digoxin; D008094:Lithium; D008274:Magnesium; D008520:Medigoxin