title: Endodermal sinus tumor of the vulva in an infant.
abstract: An endodermal sinus tumor arising in the vulva of a 22-month-old infant is reported and the features of 3 previously recorded endodermal sinus tumors of the vulva are reviewed. Despite radical surgery, radiation therapy, and chemotherapy the tumor was fatal within 6 months. Only one of the 3 previously described patients with this type of vulvar tumor has survived more than 2 years. That tumor was the smallest reported, being the only one under 2 cm in diameter.
mesh_terms: D001706:Biopsy; D001932:Brain Neoplasms / Q000556:secondary; D003520:Cyclophosphamide / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008649:Mesonephroma / Q000188:drug therapy / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D014750:Vincristine / Q000627:therapeutic use; D014846:Vulvar Neoplasms / Q000188:drug therapy / Q000401:mortality* / Q000473:pathology / Q000601:surgery
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide