title: [Pathomorphological changes in brucellosis in hares].
abstract: The morphology of 645 cases of brucellosis in hares evoked by the germs of Brucella suis, biotype 2, is described. Brucellosis had the character of chronic granulomatous process with prevailing changes in liver, spleen and in sex organs of hares of both sexes. In the sex organs of sexually immature hares the changes were detected in 2.26% of animals. The granuloma macroscopy was typical and was most discernible in liver. In the organs there prevailed solitary granulomas of the pea size. In testes two types of changes were found--coagulation necrosis and granulomatous form. In uterus node conglomerates in parametrium and mesometrium were typical. By histological analysis histiocyte granuloma of tuberculoid type with typical arrangement of layers was found. Central caseous necrosis was characterised by lesser nuclear detritus due to caryolysis. In the histiocyte layer of granulomas, an inconstant occurrence of macrocells of the Langhans type was observed. The layer of spherical cellular elements was more pronounced in smaller granulomas, in uterus and testes plasma cells prevailed. The eosinophil presence in the changed parts was low, their larger occurrence was found only in uterus, muscle lymph glands and in osteomuscular granulomas. In larger granulomas peripheral was always visible. Pyogenic component in granulomas was almost always absent.
mesh_terms: D000818:Animals; D002006:Brucellosis / Q000473:pathology / Q000662:veterinary*; D005260:Female; D008297:Male; D011817:Rabbits
vernacular_title: Patomorfologické zmĕny u brucelózních zajíců.