[Estrogen secretion by the chick embryo ovary after taxomifen treatment].
The question was posed whether tamoxifen, an anti-oestrogen had any effect on the oestrogen secretion by the Chick embryo ovary. The synthesis of oestrone and oestradiol from radiolabelled progesterone was taken as a measure of oestrogen secretion, and it was found that there was no variation. The structural changes observed by Salzgeber, Reyss-Brion and Baulieu [1] and by Scheib and Baulieu [2] may be explained by the action of tamoxifen on effector cells.
D000818:Animals; D002642:Chick Embryo; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D010053:Ovary / Q000187:drug effects* / Q000378:metabolism; D011960:Receptors, Estrogen / Q000378:metabolism; D013629:Tamoxifen / Q000378:metabolism / Q000494:pharmacology*
D004967:Estrogens; D011960:Receptors, Estrogen; D013629:Tamoxifen
Sécrétion d'oestrogènes par l'ovaire d'embryon de poulet traité par le tamoxifène.