title: [Indication and effect of intra-arterial injection of mitomycin microcapsules in the treatment of kidney cancer].
abstract: Though a variety of treatments have been employed as an adjuvant for renal cell carcinoma, none of them has proved to be significantly effective, suggesting the difficulty in the treatment of this disease. The transcatheter arterial chemoembolization utilizing mitomycin C microcapsules developed by us was applied to renal cell carcinoma with an attempt at enhancing the chemotherapy and embolization. The early results indicate that this mode of treatment facilitates radical nephrectomy due to its marked antineoplastic effects and provides a favourable prognosis in locally advanced renal cancer. The experimental and clinical profiles of intra-arterial microcapsules were presented.
mesh_terms: D000230:Adenocarcinoma / Q000098:blood supply / Q000188:drug therapy / Q000628:therapy*; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D002214:Capsules; D003692:Delayed-Action Preparations; D004285:Dogs; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D007680:Kidney Neoplasms / Q000098:blood supply / Q000188:drug therapy / Q000628:therapy*; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage*; D011379:Prognosis
chemical_list: D000903:Antibiotics, Antineoplastic; D002214:Capsules; D003692:Delayed-Action Preparations; D008937:Mitomycins; D016685:Mitomycin