Prognostic factors in medulloblastoma.
Clinical data on 30 patients with cerebellar medulloblastoma treated at this institution were analyzed. This review presents data on the clinical features, natural history of disease, and prognostic factors, as well as survival. Patients were treated uniformly using similar methods and tumor doses. The two important factors were use of optimum techniques and dosage of radiotherapy, and extent of the disease. The development of hydrocephalus had significant bearing on the prognosis, and there was a correlation between survival and clinical evidence of hydrocephalus.
D000293:Adolescent; D000328:Adult; D002524:Cerebellar Ataxia / Q000209:etiology / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000473:pathology; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011882:Radiotherapy, High-Energy / Q000379:methods; D012189:Retrospective Studies