Proteolysis and recycling of Mycobacterium tuberculosis culture filtrate tuberculoproteins.
The culture filtrate of Mycobacterium tuberculosis H37Ra has proteolytic enzyme activity which can hydrolyse extracellular tuberculoproteins. Some of the released products are transported into the cells and are incorporated into cell protein, and finally reappear in the culture filtrate as constituents of secondary tuberculoproteins. Continued extracellular proteolysis and utilization of the resultant products could produce a cyclic source of culture filtrate tuberculoproteins.
D001426:Bacterial Proteins / Q000378:metabolism*; D006868:Hydrolysis; D009169:Mycobacterium tuberculosis / Q000201:enzymology / Q000378:metabolism*
D001426:Bacterial Proteins; C030960:tuberculoprotein, Mycobacterium tuberculosis