title: The effect of intercellular distribution of drug-metabolizing enzymes on the kinetics of stable metabolite formation and elimination by liver: first-pass effects.
mesh_terms: D000082:Acetaminophen / Q000378:metabolism; D000818:Animals; D006801:Humans; D007700:Kinetics; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008102:Liver Circulation; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010615:Phenacetin / Q000378:metabolism
chemical_list: D004364:Pharmaceutical Preparations; D000082:Acetaminophen; D010615:Phenacetin