title: The treatment of childhood leukaemia in Hungary. On behalf of the Hungarian Working Party on Childhood Leukaemia.
abstract: Children suffering from leukaemia in Hungary are treated according to uniform therapeutic protocols in the framework of a national multi-centre study. Their most important clinical data are stored in the central registry and are analyzed by computerized methods. Since January, 1971, 846 new patients were entered in the registry. Initially treatment results were very poor but showed gradual improvement during the past few years, somewhat parallel to more intensive chemotherapy. The latest treatment protocol includes medium-dose MTX and the combination of ARA-C and VM-26. Preliminary data are encouraging.
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D001215:Asparaginase / Q000627:therapeutic use; D002490:Central Nervous System / Q000528:radiation effects; D002648:Child; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D006801:Humans; D006814:Hungary; D007223:Infant; D007945:Leukemia, Lymphoid / Q000175:diagnosis / Q000188:drug therapy* / Q000532:radiotherapy; D008134:Long-Term Care; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D011034:Podophyllotoxin / Q000627:therapeutic use; D012306:Risk
chemical_list: D003561:Cytarabine; D003520:Cyclophosphamide; D001215:Asparaginase; D011034:Podophyllotoxin; D008727:Methotrexate