Dysplastic nevus syndrome (B-K mole syndrome).
Six cases of dysplastic nevus syndrome were diagnosed at this institution. Two cases of the familial form of the dysplastic nevus syndrome (B-K mole syndrome) are discussed in detail to demonstrate the clinical pattern and variance of the genetic expressivity. The reader is also alerted to the possibility of a melanoma occurring in a clinically nonaffected offspring, as a de novo melanoma. Recommendation for comparative photographic documentation and possibly improved means of treatment are discussed.
D003869:Dermabrasion; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D009508:Nevus, Pigmented / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D010641:Phenotype; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D013577:Syndrome
D005472:Fluorouracil