Synergism between N-formimidoyl thienamycin and gentamicin or tobramycin against enterococci.
By the time-kill curve method, the combination of N-formimidoyl thienamycin and gentamicin showed synergism against 47 of 48 strains of enterococci, whereas the combination of N-formimidoyl thienamycin and tobramycin was synergistic against 46 strains.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004357:Drug Synergism; D013293:Enterococcus faecalis / Q000187:drug effects; D005839:Gentamicins / Q000494:pharmacology*; D015378:Imipenem; D008826:Microbial Sensitivity Tests; D013291:Streptococcus / Q000187:drug effects*; D013845:Thienamycins / Q000494:pharmacology*; D013997:Time Factors; D014031:Tobramycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D013845:Thienamycins; D015378:Imipenem; D014031:Tobramycin