Frequency of resistance to trimethoprim among isolates of Staphylococcus epidermidis and Staphylococcus saprophyticus.
Four hundred and forty-nine strains of staphylococci, 386 Staphylococcus epidermidis and 63 Staph. saprophyticus were tested by MIC and disc for susceptibility to trimethoprim. About 30% of clinically significant strains of Staph. epidermidis were resistant to trimethoprim; this fell to 12.6% in strains from normal flora. The frequency of resistance among clinically significant strains did not alter from 1976 to 1980. Strains of Staph. saprophyticus were uniformly sensitive to trimethoprim.
D003470:Culture Media; D004352:Drug Resistance, Microbial; D013210:Staphylococcus / Q000187:drug effects*; D014295:Trimethoprim / Q000494:pharmacology*
D003470:Culture Media; D014295:Trimethoprim