title: Angioimmunoblastic lymphadenopathy progressing to immunoblastic lymphoma with prominent gastric involvement.
abstract: Two unusual cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), with progression to immunoblastic lymphoma (IL) and prominent gastric involvement are presented, and detailed immunohistologic studies described. In one case, Bence Jones proteinuria of the kappa type was observed during the course of AILD and was identified immunohistochemically in lymph node biopsy specimens and at autopsy. The potential significance of an M component and the importance of recognizing gastric involvement by AILD are discussed.
mesh_terms: D001536:Bence Jones Protein / Q000652:urine; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology*; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology; D008223:Lymphoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*; D013997:Time Factors
chemical_list: D007070:Immunoglobulin A; D007147:Immunoglobulin Light Chains; D007075:Immunoglobulin M; D001536:Bence Jones Protein