[Respiratory depression after epidural opiate analgesia with buprenorphine hydrochloride? A clinical case report].
In a case of epidural application of buprenorphinehydrochloride a reduction of arterial pO2 was seen 4-6 hours after the injection. This cannot be explained as a respiratory depression due to buprenorphine, because immediately after a repeat epidural application of the drug the pO2 rose again. Reduced pO2 a long time after buprenorphine is a a result of hypoventilation caused by increased pain.
D000767:Anesthesia, Epidural; D002047:Buprenorphine; D002245:Carbon Dioxide / Q000097:blood; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009019:Morphinans; D010100:Oxygen / Q000097:blood; D010438:Peptic Ulcer Hemorrhage / Q000601:surgery*; D011659:Pulmonary Gas Exchange / Q000187:drug effects; D012119:Respiration / Q000187:drug effects*; D013276:Stomach Ulcer / Q000150:complications
D009019:Morphinans; D002245:Carbon Dioxide; D002047:Buprenorphine; D010100:Oxygen
Atemdepression nach epiduraler Opiat-Analgesie mit Buprenorphin-Hydrochlorid? Ein klinischer Fallbericht.