Growth hormone stimulates serotonin secretion into the hepatic portal circulation.
Hepatic portal plasma concentrations of free serotonin were found to be transiently but significantly elevated in normal dogs following a single injection of ovine growth hormone into a peripheral vein. The data are consistent with the concept that spike concentrations of growth hormone are capable of altering the splanchnic concentration of agents that are concerned with glucose homeostasis.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D004285:Dogs; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D008297:Male; D011168:Portal System / Q000032:analysis*; D012701:Serotonin / Q000378:metabolism*
D001786:Blood Glucose; D012701:Serotonin; D013006:Growth Hormone