Different causes for hypertriglyceridemia in male and female patients with chronic renal failure?
The changes in plasma postheparin lipolytic activities that occur in patients with chronic renal insufficiency were found to be sex dependent. Male patients showed decreased hepatic lipase activity, while female patients exhibited decreased lipoprotein lipase activity. These findings offer 1) an explanation for the hitherto confusing data on postheparin lipolytic activities in chronic renal failure reported in the literature, and 2) a further argument for a role of hepatic lipase activity in the regulation of the breakdown of plasma triglycerides.
D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications*; D008071:Lipoprotein Lipase / Q000097:blood; D008297:Male; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides; D008071:Lipoprotein Lipase