title: Decreased tear production associated with general anesthesia in the horse.
abstract: Schirmer I tear tests were conducted on 14 horses. The test was performed before and after IV administration of xylazine hydrochloride, during maintenance anesthesia with halothane in oxygen, and 3 hours after discontinuation of anesthesia. Xylazine hydrochloride did not decrease tear production from the mean base-line value of 23.94 +/- 5.23 mm/min after its IV administration. Tear production was decreased to mean values of 15.57 +/- 4.29 mm/min at 30 minutes and 13.84 +/- 4.25 mm/min at 60 minutes during the maintenance of halothane anesthesia. Three hours after anesthesia was discontinued, tear production returned to a mean value of 22.58 +/- 4.12 mm/min.
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D005260:Female; D006736:Horses / Q000378:metabolism / Q000601:surgery*; D007765:Lacrimal Apparatus / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D013666:Tears / Q000378:metabolism*; D014991:Xylazine / Q000494:pharmacology
chemical_list: D014991:Xylazine