Filicidal ring-Y chromosomes in D. melanogaster.
Ring-Y chromosomes are recovered infrequently from crosses of ring-Y-bearing males to females of certain strains (OSTER 1964). Experiments described here have unveiled a diverse class of genes that exert a maternal effect on the behavior during cleavage of these "filicidal" ring chromosomes. Cytological observations of inviable embryos have revealed that the ring-Y chromosome causes gross disorganization of the cleavage nuclei. This inviability may be equivalent to the "dominant lethality" attributed to unstable ring-X chromosomes (HINTON 1955; PASZTOR 1971). Mapping studies indicate that no single region of the normal Y is solely responsible for the unusual behavior of ring-Y chromosomes.
D000818:Animals; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D005804:Genes, Lethal; D008297:Male; D010641:Phenotype; D012730:Sex Chromosomes / Q000648:ultrastructure*; D014998:Y Chromosome / Q000648:ultrastructure*