Effect of intravenous infusion of calcium ions on the biosynthesis of the vitamin D-dependent calcium binding protein.
Calcium ions were infused into the external jugular vein of 2 groups of rachitic chicks. One group had been injected with 5 micrograms cholecalciferol (vitamin D3), while the other group remained vitamin D-deficient. After approximately 72 h the chickens were killed and intestinal mucosa homogenates were prepared for the measurement of calcium-binding protein (CaBP). The results indicate that CaBP is not biosynthesised in response to raising the extracellular calcium ion concentration, and only appears if the chickens had received cholecalciferol.
D000818:Animals; D002118:Calcium / Q000008:administration & dosage / Q000494:pharmacology*; D002135:Calcium-Binding Proteins / Q000096:biosynthesis*; D002645:Chickens; D007275:Injections, Intravenous; D064030:S100 Calcium Binding Protein G / Q000096:biosynthesis*; D014808:Vitamin D Deficiency / Q000378:metabolism
D002135:Calcium-Binding Proteins; D064030:S100 Calcium Binding Protein G; D002118:Calcium