title: Iminodiacetate complexes of technetium: an electrochemical study.
abstract: Iminodiacetate complexes of technetium are used extensively in diagnostic medical imaging, but their chemical structure and properties are yet uncertain. We studied formation of technetium-99 complexes with diethylenetetraminepentaacetate (DPTA), ethylenediaminetetraacetate (EDTA), N-(2-acetamido)iminodiacetate (ADA), and N-(2,6-dimethylphenylcarbomoylmethyl)iminodiacetate (HIDA) by tast (sampled DC) polarography, reverse-pulse polarography, controlled-potential coulometry, and amperometric titration. The products, often mixtures, varied with reaction conditions and ligand; this can explain apparent contradictions in previous studies.
mesh_terms: D004492:Edetic Acid; D004563:Electrochemistry; D006801:Humans; D007098:Imino Acids; D004369:Pentetic Acid; D011048:Polarography; D013329:Structure-Activity Relationship; D013667:Technetium; D019780:Technetium Tc 99m Lidofenin
chemical_list: D007098:Imino Acids; D019780:Technetium Tc 99m Lidofenin; D013667:Technetium; D004369:Pentetic Acid; D004492:Edetic Acid