Dithranol-UV-A phototherapy (DUVA) for psoriasis: a treatment without dressings.
Dithranol in yellow soft paraffin with 2% salicylic acid was applied daily (increasing concentrations from 0.2% to 5%) for 1 hour to twenty consecutive patients with diffuse psoriasis. The ointment was then washed off and patients were irradiated with 10 J cm-2 of UV-A radiation since the absorption spectrum of dithranol is maximum in the UV-A waveband. The median clearance time was 14 days (range 7-39 days). No dressings were required. The patients were allowed to apply an emollient if the skin became dry.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000873:Anthracenes / Q000627:therapeutic use*; D000875:Anthralin / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy* / Q000532:radiotherapy; D014467:Ultraviolet Therapy
D000873:Anthracenes; D000875:Anthralin