Comparative analysis of experimental epidural and subarachnoid bleedings in dogs.
The difference in the course and the lethal mechanism between intracranial, subarachnoid and epidural bleedings was studied in a dog model under varying conditions. Subarachnoid bleedings were usually shortlasting, self-restricting, and generally survivable. The epidural bleedings differed quantitatively and qualitatively from the subarachnoid bleedings in being larger and having a longer duration. The difference seems related mainly to the development of an arterio-venous shunt in the epidural space during the bleeding. It is suggested that the epidural arterio-venous shunt may be of importance for the course and the lethal mechanism in epidural bleeding.
D000818:Animals; D001794:Blood Pressure; D002536:Cerebral Arteries; D004195:Disease Models, Animal; D004285:Dogs; D004569:Electroencephalography; D006407:Hematoma, Epidural, Cranial / Q000503:physiopathology*; D006493:Heparin / Q000008:administration & dosage; D007427:Intracranial Pressure; D008576:Meningeal Arteries; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology*
D006493:Heparin