Fibronectin in foreign body-induced sarcomas and preneoplastic cells.
Foreign body (FB)-induced murine sarcoma cells and advanced preneoplastic cells as well as normal fibroblasts produce fibronectin (FN) in primary culture; cells at early preneoplasia do not. Hence, the neoplastic properties of FB-induced sarcomas do not depend on absence of FN. Temporary FN repression during early preneoplasia is associated with certain phenotypic cell characteristics.
D000818:Animals; D005353:Fibronectins / Q000032:analysis*; D005547:Foreign Bodies; D051379:Mice; D008808:Mice, Inbred CBA; D011230:Precancerous Conditions / Q000032:analysis* / Q000473:pathology; D012513:Sarcoma, Experimental / Q000032:analysis* / Q000473:pathology
D005353:Fibronectins