Free estradiol increase with concomitant decrease of free testosterone in plasma from normal men after incubation with spironolactone.
D004958:Estradiol / Q000097:blood*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D010949:Plasma / Q000187:drug effects; D013148:Spironolactone / Q000494:pharmacology*; D013739:Testosterone / Q000097:blood*
D013148:Spironolactone; D013739:Testosterone; D004958:Estradiol