Inhibition of the anti-D antibody-dependent cellular cytotoxicity against O, Rh-positive (R1R2) erythrocytes by O,Rh-negative (rr) competitor cells.
Anti-D antibody-dependent lymphocyte-mediated lysis of O,Rh-positive (R1R2) erythrocytes was inhibited by O,Rh-negative (rr) erythrocytes in cold target competition experiments. The degree of inhibitory effects was different with the different antisera used for sensitization. Under the same conditions the inhibition varied between 23 and 79%. The difference did not relate to the titres of the sera.
D000017:ABO Blood-Group System; D000920:Antibody-Dependent Cell Cytotoxicity; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D007106:Immune Sera; D012204:Rh-Hr Blood-Group System