A controlled study of single dosage cefamandole in the prophylaxis of wound infections in appendectomy.
A series of 102 consecutive patients undergoing appendectomy through an incision in the right iliac fossa entered a prospective randomized trial to compare the effects of a 2 gram intravenous bolus dose of cefamandole with a control study. No differences occurred in the incidence of wound infection in the two groups. We conclude that there is no place for a single preoperative dosage of cefamandole in the management of appendicitis.
D000328:Adult; D001062:Appendectomy; D002435:Cefamandole / Q000008:administration & dosage*; D002511:Cephalosporins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D011300:Preoperative Care; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002511:Cephalosporins; D002435:Cefamandole