title: Complications of metrizamide myelography.
abstract: Adverse neurobehavioral reactions have not been emphasized as a complication of metrizamide myelography. We encountered six such reactions in approximately 250 metrizamide myelograms. All reactions followed either cervical myelography or panmyelography via lumbar puncture. We also treated a single case of tonic-clonic seizure after intracranial spill of metrizamide in a patient without a history of seizure disorder, and a case of myoclonus following a thoracic metrizamide myelogram that showed a highgrade block. Metrizamide should not be used if an intrathecal block is suspected, or if the location to be studied makes intracranial spill difficult to avoid.
mesh_terms: D000328:Adult; D000368:Aged; D004569:Electroencephalography; D005119:Extravasation of Diagnostic and Therapeutic Materials; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000139:chemically induced; D008793:Metrizamide / Q000009:adverse effects*; D008875:Middle Aged; D009192:Myelography / Q000009:adverse effects*; D009207:Myoclonus / Q000139:chemically induced; D012640:Seizures / Q000139:chemically induced
chemical_list: D008793:Metrizamide