title: Failure of intensive care unit support to influence mortality from pneumococcal bacteremia.
abstract: One hundred thirty-four consecutive cases of pneumococcal bacteremia observed during a six-year period were evaluated. One hundred nineteen (89%) were associated with pneumonia. Factors associated with increased mortality were advanced age, a leukocyte count at admission of less than 5,000/cu mm, neoplastic disease, and involvement of two or more pulmonary lobes in patients with pneumonia. Mortality was 30.5% overall, and 76% in patients admitted to the intensive care unit with pneumococcal bacteremia. Pneumococcal infection continues to be an important cause of morbidity and mortality despite modern supportive care and antimicrobial therapy.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006744:Hospital Bed Capacity, 100 to 299; D006801:Humans; D007362:Intensive Care Units; D007970:Leukopenia / Q000150:complications; D008020:Life Support Care; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000401:mortality*; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000188:drug therapy / Q000401:mortality; D018805:Sepsis / Q000150:complications / Q000188:drug therapy / Q000401:mortality*; D014861:Washington
chemical_list: D000900:Anti-Bacterial Agents