Protective effect of disodium cromoglycate on propranolol challenge.
The protective activity of cromoglycate in histamine and propranolol bronchial provocation tests was studied in seven asthmatic patients by inhalation of increasing doses of histamine and propranolol in the absence and presence of inhaled cromoglycate. Cromoglycate showed a significant protective effect on the propranolol challenge, whereas no protection against histamine challenge could be observed.
D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy*; D001985:Bronchial Provocation Tests; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D011433:Propranolol
D011433:Propranolol; D004205:Cromolyn Sodium