[Extracorporeal liver perfusion in the treatment of hepatic coma].
Four patients with fulminant hepatic failure had extracorporal hemoperfusion. In selecting the patients, the following criteria were applied: Potential reversibility of the liver disease, prothrombin time under 10%, neurological coma stage III-IV. In total 11 treatments (9 treatments using baboon and 2 treatments using human livers) were performed lasting from 3 to 60 hours. One patient improved immediately after perfusion. 3 patients died; at post mortem severe oedema of the brain and acute yellow atrophy of the liver without tendency to regeneration was observed in these patients.
D000328:Adult; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications; D002675:Child, Preschool; D005112:Extracorporeal Circulation / Q000295:instrumentation*; D005260:Female; D006464:Hemoperfusion / Q000295:instrumentation; D006501:Hepatic Encephalopathy / Q000628:therapy*; D006509:Hepatitis B / Q000150:complications; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D010215:Papio
Die extrakorporale Leberperfusion zur Behandlung des Leberzerfallskoma.