Primary malignant melanoma metastatic to vitreous humor of the eye: treatment with BCNU.
A patient with malignant melanoma metastatic to the vitreous of the left eye was treated with subconjunctival as well as systemic injections of 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU). Improvement in visual symptoms and partial disappearance of tumor granules occurred, but progressive glaucoma required enucleation.
D000328:Adult; D002330:Carmustine / Q000627:therapeutic use*; D005134:Eye Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D014822:Vitreous Body
D002330:Carmustine