[Identification of lymphocyte populations producing alpha-interferon by monoclonal antibodies].
Two different leucocyte populations producing alpha-interferon can be defined by monoclonal antibodies. One non glass adherent population produces interferon after induction with Herpes and Sendaï viruses. It is characterized by anti-D44 antibody, defining both some T and NK cells, but not by anti-D66 antibody with selective reactivity for T cells. The other glass adherent population is identified by OKM1 antibody, which defines about 70% of the monocytes, and can be induced only with Sendaï virus.
D000911:Antibodies, Monoclonal / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D007370:Interferon Type I / Q000096:biosynthesis* / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D007370:Interferon Type I
Identification de populations lymphocytaires productrices d'interféron-alpha par des anticorps monoclonaux.