Interactions between acetylcholinesterase and tetra-N-alkylammonium ions.
A study of the mechanism of interaction of acetylcholinesterase with some simple tetra-N-alkyammonium ions has been made. Kinetic schemes have been proposed which are consistent with the experimental results observed in the enzyme-tetra-N-alkylammonium system in the presence of substrate and in the presence of an organophosphorus inhibitor.
D000110:Acetylcholinesterase / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002800:Cholinesterase Inhibitors; D006868:Hydrolysis; D007700:Kinetics; D008956:Models, Chemical; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D002800:Cholinesterase Inhibitors; D000644:Quaternary Ammonium Compounds; D000110:Acetylcholinesterase