Abnormal blood viscosity and haemostasis in long-standing retinal vein occlusion.
Blood viscosity and several haemostatic factors were measured in 42 patients with long-standing retinal vein occlusion and 33 control subjects. Blood viscosity, haematocrit, plasma viscosity, fibrinogen, fibrinopeptide A, and beta-thromboglobulin were increased in the 20 subjects with capillary nonperfusion or new vessels, but not in the 22 subjects without these complications. Patients with nonperfusion or new vessels also had a lower platelet count than patients without complications. Increased levels of factor VIII antigen and decreased levels of antithrombin III were found in the retinal vein occlusion group as a whole. These findings suggest that blood viscosity, platelets, and coagulation may be involved in retinal vein occlusion and its vascular complications.
D000368:Aged; D001779:Blood Coagulation Factors / Q000032:analysis*; D001809:Blood Viscosity; D002908:Chronic Disease; D003251:Constriction, Pathologic; D005260:Female; D006400:Hematocrit; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000097:blood / Q000276:immunology; D012169:Retinal Vein
D001779:Blood Coagulation Factors; D007136:Immunoglobulins