Evaluation of various N-substituted azaspiranedione derivatives as potential antimicrobial agents.
A series of N-substituted hydrazines were condensed with various spiro[4.5] and [5.5] anhydrides and the resultant N-substituted azaspiranediones were evaluated for antimicrobial activity. None displayed any significant activity in a variety of organisms tested.
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001372:Aza Compounds / Q000138:chemical synthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D013141:Spiro Compounds