title: Mutagenicity in emissions from coal- and oil-fired boilers.
abstract: The mutagenicity of emission samples from three oil-fired and four coal-fired boilers have been compared by using the Salmonella/microsome assay. Very little or no mutagenic activity was observed in samples from five of these boilers. The sample from one oil-fired boiler showed mutagenic activity of about 500 revertants/MJ, and the sample from a coal-fired fluidized bed combustor had an activity of 58,000 revertants/MJ measured with strain TA 98 in the absence of metabolic activation. All samples contained substances that were cytotoxic to the test bacteria, thus making it difficult to obtain linear dose-response curves. Mutagenic activity at low levels may remain undetected due to this toxicity of the samples. Samples with mutagenic activity below the detection limit in the Salmonella test have also been tested for forward mutations at the HGPRT locus in V79 hamster cells. Weak mutagenic effects were detected in two of the samples, whereas the sample from one oil-fired boiler remained negative. In this test, as well as in the Salmonella test, a strong cytotoxic effect could be observed with all samples.
mesh_terms: D000393:Air Pollutants / Q000633:toxicity*; D000818:Animals; D003031:Coal; D006224:Cricetinae; D005648:Fuel Oils; D009152:Mutagenicity Tests; D009153:Mutagens; D010578:Petroleum; D011210:Power Plants; D051381:Rats; D011919:Rats, Inbred Strains; D012475:Salmonella / Q000187:drug effects*
chemical_list: D000393:Air Pollutants; D003031:Coal; D005648:Fuel Oils; D009153:Mutagens; D010578:Petroleum