Glucose availability to individual cerebral structures is correlated to glucose metabolism.
Regional cerebral glucose influx was measured using quantitative autoradiography after the intravenous infusion of [2-14C]glucose for a period of 10 or 20 s. Glucose influx varied considerably among structures over an almost threefold range. When compared with rates of regional glucose utilization, a significant correlation by region was found between glucose influx and utilization, demonstrating that the glucose supply to individual cerebral structures is closely matched to their metabolic needs.
D000818:Animals; D001345:Autoradiography; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism*; D002250:Carbon Radioisotopes; D003201:Computers; D003847:Deoxyglucose / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D009928:Organ Specificity; D051381:Rats
D002250:Carbon Radioisotopes; D003847:Deoxyglucose; D005947:Glucose