Specific reading disability: identification of an inherited form through linkage analysis.
Linkage analysis in families with apparent autosomal dominant reading disability produced a lod score of 3.241. Since the traditionally accepted significance level for linkage is a lod score of 3.0, these results strongly suggest that a gene playing a major etiologic role in one form of reading disability is on chromosome 15.
D002901:Chromosomes, Human, 13-15; D004410:Dyslexia / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D010375:Pedigree