[Effect of colchamine on the rates of cell proliferation in animal tissues].
A significant decrease in the rate of cell entering into mitosis was discovered in exocrine cells of the pancreas and in liver parenchymal cells of 7-day-old rats after colchamine injections at varying times of day. These data indicate that the colchamine method should not be applied to the assessment of mitosis duration and cell proliferation rates in animal tissues.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002940:Circadian Rhythm / Q000187:drug effects; D003703:Demecolcine / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects*; D008940:Mitotic Index / Q000187:drug effects; D010179:Pancreas / Q000187:drug effects*; D051381:Rats; D013997:Time Factors
D003703:Demecolcine
Vliianie kolkhamina na tempy kletochnogo razmnozheniia v tkaniakh zhivotnykh.