[Thomsen antigen in human normal and tumor tissues].
A method of specific adsorption of appropriate antibodies from human serum was used to examine tumors of 15 patients with cancer and of 6 subjects with benign neoplasms. Tissues of cancerous tumors were found to contain Thomsen's antigen. Normal tissues of the same organ taken from the same patient did not contain the antigen nor was it contained by benign tumors. The titer of specific antibodies to Thomsen's antigen in the sera of patients suffering from cancer was considerably reduced as compared to that detected in normal subjects or in patients with benign tumors.
D000232:Adenofibroma / Q000276:immunology; D000941:Antigens / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D001940:Breast / Q000276:immunology; D001943:Breast Neoplasms / Q000276:immunology; D004064:Digestive System / Q000276:immunology; D004187:Disaccharides / Q000032:analysis*; D004912:Erythrocytes / Q000276:immunology; D005348:Fibrocystic Breast Disease / Q000276:immunology; D005770:Gastrointestinal Neoplasms / Q000276:immunology; D006801:Humans; D008168:Lung / Q000276:immunology; D008175:Lung Neoplasms / Q000276:immunology; D009369:Neoplasms / Q000276:immunology*
D000941:Antigens; D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D004187:Disaccharides; C016467:Thomsen-Friedenreich antigen
Antigen Tomsena v normal'nykh tkaniakh i opukholiakh cheloveka.