title: Selection at the alpha-Gpdh locus in experimental populations of Drosophila melanogaster.
abstract: Three sets of experiments have been conducted in order to evaluate the role of natural selection at the alpha-Gpdh locus in Drosophila melanogaster. (1) The evolution of the F-allele frequency has been followed for many generations in 13 experimental populations having different genetic backgrounds. (2) Egg-to-adult viability has been measured in synthetic populations derived from one locality (Brouilly) and the results have been compared with those of a previous experiment involving a different local population (Tostes). (3) The effects of sodium octanoate on egg-to-adult viability have been measured on the genotypes FF, FS, SF, and SS. The results demonstrate that selection operates on a small block of genes which includes the alpha-Gpdh locus.
mesh_terms: D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D004331:Drosophila melanogaster / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development; D005260:Female; D005838:Genotype; D005993:Glycerolphosphate Dehydrogenase / Q000235:genetics*; D008297:Male; D009154:Mutation; D012641:Selection, Genetic; D013045:Species Specificity
chemical_list: D005993:Glycerolphosphate Dehydrogenase