title: Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization.
abstract: Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-alpha), fibroblast interferon (IFN-beta), or immune interferon (INF-gamma) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN-alpha and IFN-beta genes to the short arm of chromosome 9(p21-->pter) and localized the IFN-gamma gene to the long arm of chromosome 12(q24.1).
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007370:Interferon Type I / Q000235:genetics*; D007371:Interferon-gamma / Q000235:genetics*; D009693:Nucleic Acid Hybridization
chemical_list: D007370:Interferon Type I; D007371:Interferon-gamma