title: [A 70-year-old controversial discussion: spleen and gonad function in medical literature].
abstract: The development of a protein-free spleen-dialysate has led to a new discussion arguing about the old question as to whether there is a link between the spleen and the endocrine system. Experimental animal-trials demonstrate that the therapy with spleen dialysate is regarded superior to an adequate dose of gonadotropins. The present contradictory results in the field of spleen research cannot yet offer a valid model of the mechanisms how it works. The therapy with spleen-dialysate in various fields of indications demonstrates first remarkable results without any serious side-effects.
mesh_terms: D000328:Adult; D000818:Animals; D007172:Erectile Dysfunction / Q000628:therapy; D005260:Female; D006062:Gonadotropins / Q000494:pharmacology; D006168:Guinea Pigs; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007246:Infertility / Q000628:therapy; D008297:Male; D008593:Menopause / Q000187:drug effects; D008875:Middle Aged; D010053:Ovary / Q000187:drug effects*; D051381:Rats; D013154:Spleen / Q000378:metabolism*; D013156:Splenectomy; D013737:Testis / Q000187:drug effects*; D014020:Tissue Extracts / Q000494:pharmacology*
chemical_list: D006062:Gonadotropins; D006728:Hormones; D014020:Tissue Extracts
vernacular_title: Seit 70 Jahren kontrovers diskutiert: Milz und Gonadenfunktion im Spiegel der Literatur.