title: An evaluation of HPLC for the screening and quantitation of benzodiazepines and acetaminophen in post mortem blood.
abstract: High performance liquid chromatographic (HPLC) methods have been developed for the analysis of benzodiazepines, some of their metabolites and for acetaminophen in post mortem blood. The methods include a single-step extraction and the use of internal standards for quantitation. Two different columns, mu-Bondapack C18 and mu-Bondapak phenyl with two different mobile phases are described. The methods presented are sensitive, reproducible, relatively selective, and have been used regularly in forensic toxicological analysis.
mesh_terms: D000082:Acetaminophen / Q000097:blood*; D001569:Benzodiazepines / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D005554:Forensic Medicine; D006801:Humans
chemical_list: D001569:Benzodiazepines; D000082:Acetaminophen