Immunologic reactivity in patients with nasopharyngeal carcinoma.
Immunologic reactivity was measured in 344 patients with nasopharyngeal carcinoma (NPC), before treatment, and in 398 age-matched control subjects. The data recorded suggest that depressed cell-mediated immunity in patients with NPC is a consequence rather than a cause of the disease. In order to reduce tumor burden in patients with NPC, radiation therapy with chemotherapy or immunopotentiation or both is recommended.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D002277:Carcinoma / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D002464:Cell Migration Inhibition; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000276:immunology*; D011379:Prognosis; D012882:Skin Tests; D013601:T-Lymphocytes