A mechanism for valproate-induced hyperammonemia.
D000641:Ammonia / Q000097:blood*; D000818:Animals; D002956:Citrulline / Q000096:biosynthesis; D005971:Glutamates / Q000378:metabolism; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D014508:Urea / Q000378:metabolism*; D014635:Valproic Acid / Q000009:adverse effects*
D005971:Glutamates; D002956:Citrulline; D014635:Valproic Acid; D000641:Ammonia; D014508:Urea; C016195:N-acetylglutamic acid