title: Properties of the spike afterhyperpolarization in pyramidal tract neurons.
abstract: Features of the spike afterhyperpolarization (AHP) recorded intracellularly have been analyzed in fast pyramidal tract neurons of cats. Cell input conductance increases during the AHP, possibly because of a change in potassium conductance, as suggested by an AHP equilibrium potential 10--15 mV negative to the resting membrane potential. When more spikes are evoked in succession, AHPs following the first one are strongly reduced in amplitude. The effect is virtually maximal (30--50% of the control) after a single spike and fades out by 200-400 ms after the last spike. At short interspike intervals the initial time course of the depression is hidden by summation occurring between consecutive AHPs.
mesh_terms: D000818:Animals; D002415:Cats; D002463:Cell Membrane Permeability; D004553:Electric Conductivity; D005071:Evoked Potentials; D011188:Potassium / Q000378:metabolism; D011712:Pyramidal Tracts / Q000502:physiology*
chemical_list: D011188:Potassium