title: The role of single and double-contrast radiography in the diagnosis of reflux esophagitis.
abstract: Sixty-seven patients with endoscopically proved esophagitis and 25 patients who had no esophageal disease were examined by double-contrast esophagography, followed by a single-contrast examination. The radiographs were evaluated separately and as a combined examination technique by three independent radiologists in a blind analysis. The respective sensitivities were 77% for the single-contrast examination, 80% for the double-contrast examination, and 88% for the combined examination method with no significant statistical difference (P = 0.05). The sensitivity increased for all methods with an increased severity of esophagitis. False positives more frequently occurred with double-contrast radiography, leading to similar accuracy rates for all methods (74% to 77%). The double-contrast examination technique showed an advantage over single-contrast radiography only if a granular pattern and erosions were the only radiographically detectible features of esophagitis. The use of the combined examination technique is recommended.
mesh_terms: D000328:Adult; D000368:Aged; D001466:Barium Sulfate; D004942:Esophagitis, Peptic / Q000000981:diagnostic imaging*; D004947:Esophagus / Q000000981:diagnostic imaging*; D005189:False Positive Reactions; D006801:Humans; D008722:Methods; D008875:Middle Aged; D011859:Radiography
chemical_list: D001466:Barium Sulfate