Comparison of ossicular replacement materials in a mouse ear model.
Four biomaterials, UF45S5 Bioglass, Silastic, Plasti-Pore, and Proplast, were used to replace the incus in a mouse ear model. Bioglass, a bioactive glass ceramic, compared favorably with the other test materials in maintaining surgical positioning between malleus and stapes and remaining stable to a blast of nitrogen gas and to pick manipulation. In a short-term animal study, Bioglass showed histocompatibility comparable to that of these other implant materials now used in ossicular replacement surgery in humans.
D000818:Animals; D002516:Ceramics; D004429:Ear Ossicles / Q000166:cytology / Q000601:surgery*; D007188:Incus / Q000601:surgery; D051379:Mice; D011095:Polyethylenes; D011126:Polypropylenes; D011428:Proplast; D019736:Prostheses and Implants; D012826:Silicone Elastomers
C022107:Bioglass; C016674:Plastipore; D011095:Polyethylenes; D011126:Polypropylenes; D011428:Proplast; D012826:Silicone Elastomers