title: Demonstration of vascular redistribution after carotid clamping in rats.
abstract: In Long Evans rats, the vertebral arteries supply only the brain stem. Simultaneous application of clamps to both carotid arteries results in a considerable fall of cerebral blood flow and eventually death. If an interval of about 4 days is allowed between the clamping of the 2 carotids, redistribution of blood flow takes place. Owing to this mechanism, 50% of the rats survive with a satisfactory restoration of cerebral blood flow.
mesh_terms: D000818:Animals; D002339:Carotid Arteries / Q000502:physiology*; D002560:Cerebrovascular Circulation; D003250:Constriction; D008297:Male; D051381:Rats; D012039:Regional Blood Flow; D013997:Time Factors