[Conjunct changes in the resistance and engorgement of the cerebral vessels in shifts in the blood gas composition].
In anesthetized cats, under perfusion and with constant volume of the hemodynamically isolated brain, hypercapnia and hypoxia led to a decrease of cerebral vessels resistance and to a reduction of the brain blood flow, whereas a decrease in the PCO2 and an increase in the PO2 in the blood exerted on opposite effect. The different responses of the vessels had some similar features in respect to threshold changes of the PCO2 and PO2, to potentiation of effects of both parts of the brain vascular system on increased shifts of the blood gas tension, to greater sensitivity of both parts to PCO2 changes, to effect of the blood gas tension on reactivity of both parts to noradrenaline. The authors suggest a possibility of alterations of the filter-absorption interrelationships in the brain due to different responses of arterial and venous vessels to changes of the blood gas tension.
D000818:Animals; D001810:Blood Volume; D002245:Carbon Dioxide / Q000097:blood*; D002415:Cats; D002536:Cerebral Arteries / Q000502:physiology*; D002560:Cerebrovascular Circulation; D006935:Hypercapnia / Q000503:physiopathology; D002534:Hypoxia, Brain / Q000503:physiopathology; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D014655:Vascular Resistance
D002245:Carbon Dioxide; D010100:Oxygen
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