A study of rDNA magnification phenomenon in a repair-recombination deficient mutant of Drosophila melanogaster.
The rDNA magnification process consists of a rapid and inheritable rDNA increase occurring in bobbed males: in a few generations the bb loci acquire the wild-type rDNA value and reach a bb+ phenotype.--We have analyzed the rDNA magnification process in the repair-recombination-deficient mutant mei9a, both at the phenotypical and rDNA content levels. In mei9a bb double mutants the recovery of bb+ phenotype is strongly disturbed and the rDNA redundancy value fails to reach the wild-type level. The strong effect of this meiotic mutation on rDNA magnification suggests a close relationship between this phenomenon and the repair-recombination processes.
D000818:Animals; D004247:DNA / Q000235:genetics; D004260:DNA Repair; D004261:DNA Replication; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D008297:Male; D008540:Meiosis; D009154:Mutation; D012335:RNA, Ribosomal / Q000235:genetics*
D012335:RNA, Ribosomal; D004247:DNA