Evolution of pontine and extrapontine myelinolysis.
We report on the serial computed tomographic (CT) changes in the brainstem and cerebral hemispheres of a woman with autopsy-proven pontine and extrapontine myelinolysis who survived for 14 months. The earliest finding was diffuse decreased attenuation values of the gray matter resulting in poor gray-white matter differentiation. Anterior temporal lobe involvement, a finding not previously reported, was demonstrated on CT and confirmed by neuropathologic examination.
D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D003711:Demyelinating Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011149:Pons / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed