title: The changing role of external-beam irradiation in the management of malignant tumors of the major salivary glands.
abstract: Postoperative irradiation reduces the local recurrence rate for malignant salivary gland tumors. Less extensive surgery followed by immediate radiotherapy is possible without decreasing local control; moreover, cosmetic appearance and physiological function are preserved. Local tumor control was achieved in 16 out of 17 patients without gross tumor using a dose of 6,000 rad/6 wk. Combined photon and electron beams give better cosmetic and functional results than either modality alone. Irradiation with greater than or equal to 7,000 rad should be employed in unresectable cases and may effect tumor control.
mesh_terms: D000328:Adult; D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010307:Parotid Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D011882:Radiotherapy, High-Energy; D012468:Salivary Gland Neoplasms / Q000532:radiotherapy*; D013365:Submandibular Gland Neoplasms / Q000532:radiotherapy* / Q000601:surgery
chemical_list: D003037:Cobalt Radioisotopes