The effect of hepatic metabolism on the production and toxicity of reactive metabolites in extrahepatic organs.
D000818:Animals; D001711:Biotransformation; D001969:Bromobenzenes / Q000378:metabolism / Q000633:toxicity; D004790:Enzyme Induction; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008168:Lung / Q000187:drug effects; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism / Q000633:toxicity; D013729:Terpenes / Q000378:metabolism / Q000633:toxicity; D014116:Toxicology
D001969:Bromobenzenes; D004364:Pharmaceutical Preparations; D011763:Pyrrolizidine Alkaloids; D013729:Terpenes; C001470:4-ipomeanol