The aphrodisiac effect of low doses of (-) deprenyl in male rats.
The effects of single doses of (-)deprenyl, in comparison to J-508, U-1424, pargyline and clorgyline, on the sexual performance of male rats were tested. (-)Deprenyl (0.25 and 1 mg/kg, respectively) exerted a true, long-lasting aphrodisiac effect, on sexually sluggish male rats, whereas clorgyline, U-1424 and J-508 failed to act similarly. Pargyline facilitated the sexual performance of the rats, but only transiently.
D000818:Animals; D001046:Aphrodisiacs; D003307:Copulation; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D010293:Pargyline / Q000494:pharmacology; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats; D012642:Selegiline / Q000494:pharmacology*; D012726:Sexual Behavior, Animal / Q000187:drug effects; D013997:Time Factors
D001046:Aphrodisiacs; D008996:Monoamine Oxidase Inhibitors; D010627:Phenethylamines; D012642:Selegiline; D010293:Pargyline