title: Improvement in intra-aortic balloon pumping and evaluation of its efficacy by electrode methods of control.
abstract: A basically new design for the reversing balloon pump has been proposed for increasing the efficacy of intra-aortic balloon pumping (IABP). The device not only causes a significant increase in discharge, but also permits control of the central and peripheral circulation within the desired limits owing to back-and-forth movements (like a piston) of the balloon pump. Standard one- and two-chamber balloon pumps were compared. In addition to traditional hemodynamic and biochemical indexes, the efficacy of IABP was assessed based on electrode monitor control of PO2 and pH in the myocardium, peripheral tissues, and circulating blood. Based on 54 experiments on dogs, it was found that IABP with reversing balloon pumps in synchronous pulsation resulted in survival of 69% of the cases; PO2 and pH levels in the myocardium, tissues, and blood in the coronary sinus were close to normal, and coronary blood flow and peripheral circulation were increased. With standard one-chamber balloon pumps, the survival rate did not exceed 33.4%; PO2 and pH in the peripheral tissues reached critical levels.
mesh_terms: D000818:Animals; D001243:Assisted Circulation / Q000295:instrumentation*; D003326:Coronary Circulation; D004566:Electrodes; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D006863:Hydrogen-Ion Concentration; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption; D010313:Partial Pressure; D010527:Perissodactyla