Tissue distribution and elimination of chlorinated naphthalenes in mice.
Male pathogen-free JCL:ICR mice were dosed i.p. 1 mg of 1,8-and 2,7-dichloronaphthalenes and octachloronaphthalene dissolved in olive oil. The highest levels of all chlorinated naphthalenes were found in adipose tissue. The biological half-life of octachloronaphthalene was longer than both dichloronaphthalenes while the half-life of 2,7-dichloronaphthalene was longer than that of 1,8-dichloronaphthalene in most tissues.
D000818:Animals; D006207:Half-Life; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009281:Naphthalenes / Q000378:metabolism*; D013329:Structure-Activity Relationship; D014018:Tissue Distribution
D006843:Hydrocarbons, Chlorinated; D009281:Naphthalenes