title: [Citicoline activity in senile mental decay].
abstract: A brief report on the role of neurotransmittors (especially dopamine) depletion in cerebral aging and the development of certain pathological conditions in the elderly is presented. This is followed by a report on the results obtained by the administration of citicoline (500 mg/per diem intramuscularly for 20 days) to a group of 24 elderly patients with senile mental decay. A significant improvement (p less than 0.01) in mental performance was observed in all patients and no side effects were noted.
mesh_terms: D000368:Aged; D002794:Choline / Q000031:analogs & derivatives*; D003566:Cytidine Diphosphate Choline / Q000008:administration & dosage*; D003704:Dementia / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008609:Mental Status Schedule; D013997:Time Factors
chemical_list: D003566:Cytidine Diphosphate Choline; D002794:Choline
vernacular_title: Attività della citicolina nel decadimento mentale senile.