title: Hepatitis and jaundice associated with measles in young adults. An analysis of 65 cases.
abstract: We analyzed the clinical course of 65 adult patients hospitalized because of measles during the years 1975 and 1981-1982. Liver involvement was found in 80% (52/65) of the patients, five patients had clinical jaundice. The disturbances of liver function tests reached their peak values between days 5 and 10 of the disease. In this study of measles in adulthood we have three observations of unusual interest: (1) hepatitis occurs commonly in the more severely ill patients and it may manifest clinically as jaundice; (2) long-term follow-up (up to seven years) shows a clear tendency to complete resolution of the liver damage; (3) there is a clear correlation between the severity of hepatic involvement and the occurrence of secondary bacterial infections.
mesh_terms: D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000453:epidemiology / Q000209:etiology; D004196:Disease Outbreaks / Q000453:epidemiology; D006505:Hepatitis / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D007557:Israel; D007565:Jaundice / Q000453:epidemiology / Q000209:etiology*; D008111:Liver Function Tests; D008457:Measles / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D013997:Time Factors