Antigenic variation of Newcastle disease virus strains detected by monoclonal antibodies.
Forty Newcastle disease virus strains and isolates could be placed in eight distinct antigenic groups on their ability to induce binding of nine mouse monoclonal antibodies, raised against strain NDV-Ulster 2C, to infected MDBK cells as assessed by an indirect immuno-peroxidase test. Viruses placed in each group appeared to share both biological and epizootiological properties.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D001667:Binding, Competitive; D002417:Cattle; D002478:Cells, Cultured; D014644:Genetic Variation; D006385:Hemagglutination Inhibition Tests; D007668:Kidney; D009522:Newcastle disease virus / Q000276:immunology*; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral