[Depressor effect of normobaric oxygen on the mouse lymphoid system].
Mice exposed to pure oxygen develop a lethal edematous pulmonary disease. This Note demonstrates, in these Mice, a lymphoid involution with blood lymphopenia and severe decrease in thymic weight and cellularity. The thymus was completely destroyed following 96 hrs. exposure. The possible role of these leucocyte alterations in normobare oxygen toxicity should be considered.
D000818:Animals; D005260:Female; D007962:Leukocytes / Q000187:drug effects / Q000502:physiology; D008208:Lymphatic System / Q000187:drug effects / Q000502:physiology*; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology; D010100:Oxygen / Q000633:toxicity*; D013950:Thymus Gland / Q000187:drug effects / Q000502:physiology
D010100:Oxygen
Mise en évidence de l'effet dépresseur de l'oxygène normobare sur le système lymphoïde de la souris.