Serial determinations of antiplatelet antibodies in a patient with Hodgkin's disease and autoimmune thrombocytopenia.
This case report describes a patient who presented with Stage IV B Hodgkin's disease and autoimmune thrombocytopenia. Prior to the institution of therapy the presence of platelet-associated IgG was documented. When the patient was treated with steroids and chemotherapy, the thrombocytopenia resolved and platelet-associated IgG disappeared. Splenectomy alone did not correct the thrombocytopenia. The literature on Hodgkin's disease and autoimmune thrombocytopenia is reviewed.
D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology*; D001792:Blood Platelets / Q000276:immunology*; D005260:Female; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D013156:Splenectomy; D013921:Thrombocytopenia / Q000150:complications* / Q000276:immunology / Q000628:therapy
D001323:Autoantibodies