Dose-dependent response of FSH, flushes and urinary calcium to oestrogen.
The reduction of gonadotrophin levels, urinary calcium and hot flushes in post-menopausal patients by ethinyl oestradiol is shown to be dose dependent, near maximum response being achieved by a dose of 15 micrograms daily. Equivalent ethinyl oestradiol doses to a number of other gonadal hormone preparations have been assessed using the derived dose-response curve of the reduction in urinary calcium.
D002118:Calcium / Q000652:urine*; D002979:Climacteric / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D012044:Regression Analysis
D004967:Estrogens; D005640:Follicle Stimulating Hormone; D002118:Calcium