Prognosis of symptomatic coarctation of the aorta in infancy.
Medical and surgical advances have improved the outlook for infants with symptomatic coarctation of the aorta. To help predict the clinical course of individual patients and to aid in individualizing their treatment, a 10-year experience with this condition was reviewed. Of 97 infants with symptomatic coarctation, 10 had isolated defects. In these patients, medical treatment was successful and surgical intervention could be postponed to allow for growth. The 87 other patients with associated cardiac defects were generally sicker at presentation and required earlier operation. Eleven of these died before surgical correction, 10 died at the time of repair, and 13 died later. The overall survival rate after 8 years was 62%, with most deaths occurring in the first 6 months of life. Late surgical results are flawed by a 32% rate of residual coarctation. Late postoperative hypertension is uncommon, and is usually attributable to a residual coarctation.
D000206:Actuarial Analysis; D001017:Aortic Coarctation / Q000150:complications / Q000401:mortality* / Q000601:surgery; D006328:Cardiac Catheterization; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011184:Postoperative Period; D011379:Prognosis