title: Plain bupivacaine 0.5%: a preliminary evaluation as a spinal anaesthetic agent.
abstract: Three hundred and forty consecutive patients received successful spinal anaesthesia with 0.5% plain bupivacaine. A small randomised study of 40 of these cases showed little difference between 3.5 and 3 ml; however, analysis of its use in 200 patients receiving 3.5 ml (mean block T10.5 +/- 1 segment) and 100 receiving 3 ml (T10 +/- 0.5 segment) confirmed the impression that the smaller volume produced a more limited range of segmental block, which was desirable notably in the over-70-year age group. The main complications were hypotension (14.1%) and headache (1.5%).
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000775:Anesthesia, Spinal / Q000009:adverse effects; D002045:Bupivacaine / Q000008:administration & dosage* / Q000009:adverse effects; D004341:Drug Evaluation; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies
chemical_list: D002045:Bupivacaine