Deficiency of androgen receptors in male pseudohermaphroditism.
A diagnosis of androgen receptor deficiency was made in a male with ambiguous genitalia during the neonatal period. Since the neonate had a small hypospadiac phallus with laboratory evidence of a receptor deficiency and clinical unresponsiveness to high levels of androgen, it was decided to assign a female gender. Bilateral orchiectomy and phallic recession were performed.
D000293:Adolescent; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D012734:Disorders of Sex Development / Q000175:diagnosis*; D005837:Genitalia, Male; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010413:Penis / Q000502:physiology; D011944:Receptors, Androgen / Q000032:analysis*; D011987:Receptors, Steroid / Q000032:analysis*; D012611:Scrotum; D012727:Sex Characteristics; D012732:Sex Determination Analysis; D012867:Skin / Q000032:analysis; D013737:Testis / Q000601:surgery
D006063:Chorionic Gonadotropin; D011944:Receptors, Androgen; D011987:Receptors, Steroid