[Effect of nitroglycerin on various enzyme activity in the peri-infarction area of the myocardium].
A histochemical study of the activity of some enzymes in the peri-infarction area of rabbit myocardium in response to nitroglycerin showed the latter to increase the activity of oxydative-reductive enzymes in heart tissue, reduce acidosis, intensify the pentosephosphate cycle and contribute to a more intensive resorption of necrotized muscular fibres. These effects are conducive to better cardiomyocytes survival in the peri-infarction area and a more intensive organization of the infarction, this reducing the size of the affected area.
D000818:Animals; D004950:Esterases / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology*; D005996:Nitroglycerin / Q000627:therapeutic use*; D010088:Oxidoreductases / Q000378:metabolism*; D011817:Rabbits; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013997:Time Factors
D010088:Oxidoreductases; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013385:Succinate Dehydrogenase; D005969:Glutamate Dehydrogenase; D004950:Esterases; D005996:Nitroglycerin
Vliianie nitroglitserina na aktivnost' nekotorykh fermentov v periinfarktnoĭ zone miokarda.