title: Intermittent, continuous outpatient dobutamine infusion in the management of congestive heart failure.
abstract: The use of outpatient dobutamine infusions by a small, portable infusion pump in 3 patients with intractable congestive heart failure (CHF) is described. With this therapy left ventricular function improved and CHF resolved in each. Tolerance to dobutamine was obviated by giving infusions twice weekly. Except for 3 mild infections around the catheter exit site, there have been no complications of this therapy is 58 cumulative patient weeks.
mesh_terms: D002395:Catecholamines / Q000008:administration & dosage*; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation; D004280:Dobutamine / Q000008:administration & dosage* / Q000627:therapeutic use; D004361:Drug Tolerance; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010044:Outpatient Clinics, Hospital; D011788:Quality of Life; D013318:Stroke Volume / Q000187:drug effects; D013997:Time Factors
chemical_list: D002395:Catecholamines; D004280:Dobutamine