[Growth rate of malignant tumors of the large intestine].
The rates of colonic tumor growth were studied on the basis of evaluation of the case histories of 19 cancer patients in whom dynamic endocolonoscopy had been carried out. In some cases, malignant tumors appeared in the colon within 12 months after previous colonoscopy. Tumors were under 2.0 cm in size and were not accompanied by any clinical symptoms. Repeated endoscopic examinations performed within a period of 1-3 years detected large tumors which caused the constriction of colonic lumen. Clinical symptoms developed in such patients approximately 1-4 months prior to tumor detection. It is concluded that although the rates of growth of colonic malignancies are rather high, tumorigenesis is preceded by a long-term stage of preclinical disease.
D003110:Colonic Neoplasms / Q000473:pathology*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D013997:Time Factors
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