Cumulative dose-effect curves in a conflict test with incremental shock.
Cumulative dose-effect curves were generated for chlordiazepoxide, diazepam, meprobamate, pentobarbital, morphine, and d-amphetamine in a Geller-Seifter conflict test with incremental shock. The anxiolytics increased responses in conflict significantly at one or more doses, whereas the non-anxiolytics d-amphetamine and morphine produced dose-related decreases. Results were consistent with previous data from the conventional one-dose-per-session design.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002369:Castration; D003220:Conflict, Psychological; D004305:Dose-Response Relationship, Drug; D004597:Electroshock; D005260:Female; D011619:Psychotropic Drugs / Q000494:pharmacology*; D051381:Rats
D011619:Psychotropic Drugs