[Modified neuroleptanalgesia with buprenorphine].
A modification of neuroleptanalgesia by substituting fentanyl with buprenorphine is presented. Both anaesthesia techniques could be applied alternatively. We did not recognize any significant difference between the two groups concerning haemodynamics, the secretion of the so called stress hormones (antidiuretic hormone, cortisol) as well as the postoperative respiratory depression. The long lasting analgesia, which could be achieved by buprenorphine, can be advantageous in certain surgical interventions. The lack of a potent antagonist for buprenorphine in addition to its longer half-life for--not being of advantage in any anaesthesia--is discussed.
D000328:Adult; D002047:Buprenorphine / Q000008:administration & dosage*; D002245:Carbon Dioxide / Q000097:blood; D004573:Electrolytes / Q000097:blood; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009019:Morphinans / Q000008:administration & dosage*; D009458:Neuroleptanalgesia / Q000379:methods*; D010100:Oxygen / Q000097:blood; D011388:Prolactin / Q000097:blood; D012119:Respiration / Q000187:drug effects
D004573:Electrolytes; D009019:Morphinans; D002245:Carbon Dioxide; D002047:Buprenorphine; D011388:Prolactin; D010100:Oxygen; D005283:Fentanyl; D006854:Hydrocortisone
Modifizierte Neuroleptanalgesie mit Buprenorphin.