title: Alveolar deposition of sized particles of 239PuO2 in the mouse.
abstract: Data on the alveolar deposition of 239PuO2 particles in the mouse are presented. It is shown that alveolar deposition falls with increasing activity median aerodynamic diameter (AMAD) over the range 0.6 to 2.4 microns. In the mouse, any peak in alveolar deposition must occur at an AMAD of less than 1 micron. Information is also provided on the relative lobar concentrations (RLCs) of 239PuO2. The RLC is greatest in the right apical lobe and increases quite sharply with AMAD. The RLCs of the other lobes of the right lung decline with AMAD. The RLC in the left lobe is relatively unaffected by AMAD.
mesh_terms: D000336:Aerosols; D000818:Animals; D005260:Female; D008297:Male; D051379:Mice; D009929:Organ Size; D010316:Particle Size; D011005:Plutonium / Q000032:analysis*; D011650:Pulmonary Alveoli / Q000032:analysis* / Q000473:pathology
chemical_list: D000336:Aerosols; C026885:plutonium dioxide; D011005:Plutonium