Net metabolic changes of zinc, copper, nitrogen, and potassium balances in skeletal trauma patients.
Zinc, copper, nitrogen, and potassium balances of 10 male skeletal trauma patients were determined over 5-6 days each. Nutrition consisted of electrolyte/glucose and/or blood/blood product infusions. Patients were started on balance studies within 24 hr following injury. Zinc and copper were analyzed by atomic absorption while nitrogen was measured by the microKjeldahl technique and potassium by flame photometry. The mean daily balances for these patients were -1563 micrograms zinc, -266 micrograms copper, -20.0 g nitrogen and -29 mEq potassium for 5 patients receiving electrolyte/glucose infusions and +1273 micrograms zinc, +322 micrograms copper, -12.9 g nitrogen, and -26 mEq potassium for 5 patients receiving blood/blood products in addition to electrolyte/glucose. Routine daily maintenance supplementation of 2 mg zinc and 2 mg copper is recommended for skeletal trauma patients on electrolyte/glucose and those on electrolyte/glucose with blood/blood products intravenous infusions. Further balance studies are necessary to ascertain the level of zinc and copper supplementation needed by skeletal trauma patients receiving different nutritional support.
D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D001831:Body Temperature; D001842:Bone and Bones / Q000293:injuries* / Q000378:metabolism; D003300:Copper / Q000378:metabolism* / Q000652:urine; D002149:Energy Intake; D005243:Feces / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism* / Q000652:urine; D010288:Parenteral Nutrition; D011188:Potassium / Q000378:metabolism* / Q000652:urine; D013997:Time Factors; D015032:Zinc / Q000378:metabolism* / Q000652:urine
D003300:Copper; D015032:Zinc; D009584:Nitrogen; D011188:Potassium