Subacute pneumopathy during amiodarone therapy.
A patient with types A and B of Wolff-Parkinson-White syndrome developed subacute pneumonitis during long-term treatment with amiodarone. The pneumopathy occurred only when the maintenance dose was increased to 800 mg/day. Lung specimens obtained by transbronchial biopsy showed chronic pneumonitis with C3 deposition by immunofluorescence. Pulmonary signs spontaneously disappeared two months after the drug was discontinued.
D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D001572:Benzofurans / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D011014:Pneumonia / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology; D014927:Wolff-Parkinson-White Syndrome / Q000188:drug therapy
D001572:Benzofurans; D000638:Amiodarone