Low dose rhesus immunoprophylaxis after early induced abortions.
A dose of 50 microgram anti-D immunoglobulin was administered as rhesus immunoprophylaxis following induced abortion performed by suction curettage before the thirteenth week of pregnancy in 463 consecutive patients. A feto-maternal blood loss of less than 2 ml was detected in 44 women (12%). After 6 months, a follow-up of 381 patients (82%) established that none of these patients was rhesus immunized with in vitro demonstrable antibodies. It is concluded that the low dose of anti-D administered is to be recommended for rhesus immunoprophylaxis after first trimester abortion.
D000028:Abortion, Induced; D000888:Antibodies, Anti-Idiotypic / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007072:Immunoglobulin D / Q000276:immunology*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D007072:Immunoglobulin D; D012204:Rh-Hr Blood-Group System