title: [Repair processes in the pancreas after cold injury].
abstract: Electron microscopy of the pancreas has shown after focal ethyl chloride cooling that reparative processes spreading from the borders to the epicenter of the affected parts involved (1) intracellular regeneration of partially damaged acinar cells, (2) proliferation of the epithelium of unaffected ducts, (3) proliferation of fibroblasts and capillary endothelium to form a fibrous capsule around the focus of necrosis. After sequestration of the focus of necrosis the partially damaged acinar cells of the border area underwent amitosis without cytotomy followed by the recovery of lost organelles. No acinar cells were observed to occur. Canalicular proliferates became differentiated mainly in islet cells. However, the main mass of the canalicular acinar derivatives of the border area experienced atrophy and cicatrization to form a fibrous capsule around the focus of necrosis. The compensation of the lost part of the excretory parenchyma was preceded by hypertrophy of acinar cells of undamaged segments of the pancreas.
mesh_terms: D000818:Animals; D003080:Cold Temperature / Q000009:adverse effects*; D008854:Microscopy, Electron; D010179:Pancreas / Q000293:injuries / Q000502:physiology* / Q000648:ultrastructure; D010195:Pancreatitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D012038:Regeneration
vernacular_title: Reparativnye protsessy v podzheludochnoĭ zheleze posle ee kholodovogo povrezhdeniia.