[Posttraumatic pituitary insufficiency. Value of pretreatment with LHRH in the differentiation between pituitary and hypothalamic deficits].
A patient presented with post-traumatic hypopituitarism, where transient diabetes insipidus, high prolactin levels and prolonged and delayed TSH rise after TRH suggested a hypothalamic lesion. Although there was no gonadotropin response to LHRH as one could have expected, following repeated administration of LHRH, the LH response returned to normal, thus confirming a hypothalamic cause for his hypogonadism.
D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003919:Diabetes Insipidus / Q000209:etiology; D003937:Diagnosis, Differential; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D006801:Humans; D007006:Hypogonadism / Q000209:etiology*; D007018:Hypopituitarism / Q000188:drug therapy / Q000209:etiology*; D007027:Hypothalamic Diseases / Q000175:diagnosis*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011388:Prolactin / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone
D007987:Gonadotropin-Releasing Hormone; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D013972:Thyrotropin
Insuffisance hypophysaire post-traumatique. Intérêt du pré-traitement par la LHRH dans la différenciation des déficits hypophysaires et hypothalamiques.