title: Genetic variation of the sixth component of complement (C6) in the Manx shearwater (Puffinus p. puffinus).
abstract: A polymorphism in the sixth complement component (C6) has been investigated by isoelectric focusing. The results indicate that C6 is coded by genes at a single autosomal locus. Six structural alleles have been identified, a null allele is also postulated. Five island colonies of Shearwater were investigated, two alleles C6 A and C6 B predominate in all sites. The ability of rabbit C5 and C7 to combine successfully with avian C6 indicates the functional sites of these molecules are highly conserved.
mesh_terms: D000818:Animals; D001717:Birds / Q000235:genetics*; D001793:Blood Preservation; D003183:Complement C6 / Q000032:analysis / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006363:Hebrides; D006461:Hemolysis; D005779:Immunodiffusion; D007525:Isoelectric Focusing; D008297:Male; D008954:Models, Biological; D009660:Northern Ireland; D010641:Phenotype; D011110:Polymorphism, Genetic; D011817:Rabbits
chemical_list: D003183:Complement C6