Comparison of two indices of glycemic control in diabetic subjects: glycosylated serum protein and hemoglobin.
Glycosylated serum protein (GSP) and glycosylated hemoglobin (GHb) were measured in 263 insulin-dependent and 41 non-insulin-dependent diabetic subjects. Both indices provided useful information in type II diabetes, but were extremely poor in judging control in type I diabetes. In both groups, there was poor correlation of the fasting serum glucose with either GSP or GHb. Only 4% of type I diabetic subjects had normal values for both GSP and GHb. Of subjects with elevated GSP, 98% had elevated GHb; 25% of subjects with elevated GHb values had normal values for GSP.
D000367:Age Factors; D001786:Blood Glucose / Q000032:analysis*; D001798:Blood Proteins / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood*; D005215:Fasting; D006023:Glycoproteins; D006441:Hemoglobin A / Q000032:analysis*; D006801:Humans; D011627:Puberty; D000093422:Glycated Serum Proteins
D001786:Blood Glucose; D001798:Blood Proteins; D006023:Glycoproteins; D006441:Hemoglobin A; D000093422:Glycated Serum Proteins