7,7'-Bi-(2-cyano-4-aryl) alkyl (-1H-tetrahydrobenzodiazepines-1,5).
Bi-benzodiazepine nitriles 1-8 were obtained in a modified manner as potential psychotropic agents. In screening experiments 3 acted as a potent antagonist of pentetrazol, compounds 1-4 and 7 had antiserotonin action, and 5 potentiated the effects of DOPA [5].
D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis; D001569:Benzodiazepines / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D012702:Serotonin Antagonists / Q000138:chemical synthesis
D000927:Anticonvulsants; D012702:Serotonin Antagonists; D001569:Benzodiazepines; D004295:Dihydroxyphenylalanine; D010433:Pentylenetetrazole