title: The use of glucagon in hydrostatic reduction of intussusception: a double-blind study of 30 patients.
abstract: Thirty patients were referred for hydrostatic reduction of ileocolic intussusception. Children with suspected gangrenous bowel or sensitivity to glucagon were excluded from the investigation. A standard protocol for the procedure was used in all patients, including the intravenous administration of glucagon or placebo (0.05 mg/kg) when the intussusception was encountered. Successful reduction was achieved in 53% of both control and glucagon-treated patients. Analysis of the length of the procedure and the ease of reduction of the intussusception indicated no difference in the two groups. This multicenter double-blind study failed to show any therapeutic value of glucagon in hydrostatic reduction of intussusception.
mesh_terms: D001466:Barium Sulfate; D002648:Child; D004311:Double-Blind Method; D004733:Enema; D005934:Glucagon / Q000627:therapeutic use*; D006801:Humans; D007077:Ileal Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D007443:Intussusception / Q000000981:diagnostic imaging / Q000628:therapy*; D011859:Radiography
chemical_list: D001466:Barium Sulfate; D005934:Glucagon