title: Clinical significance of the radioisotope test using I-131 labelled serum albumin for evaluating the peripheral circulation in the foot during a period of reactive hyperemia.
abstract: The radioisotope test using I-131 labelled serum albumin, performed during a period of reactive hyperemia, provides quantitative data which express the rate at which radioactive blood flowing from the leg replaces the non-radioactive blood present in the foot. It has been applied in normal subjects and in patients with arterial occlusions in the lower limbs. High washout rates, i.e. small M/2 index values, were found in the former, whereas low washout rates with higher M/2 indices were observed in the latter. Surprisingly, patients with a very low washout rate could be without subjective symptoms. The usefulness of the test in clinical practice is explained.
mesh_terms: D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging; D005260:Female; D005528:Foot / Q000098:blood supply*; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D012709:Serum Albumin
chemical_list: D007457:Iodine Radioisotopes; D012709:Serum Albumin