title: Extrapolations from species to species and from various cell types in assessing risks from chemical mutagens.
abstract: Strategies for estimating human mutation frequencies can be based on extrapolations of dose: mutation ratios in other species.
mesh_terms: D000818:Animals; D002460:Cell Line; D004305:Dose-Response Relationship, Drug; D004330:Drosophila / Q000235:genetics; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D006801:Humans; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology; D009154:Mutation; D012306:Risk; D013045:Species Specificity; D013094:Spermatozoa / Q000187:drug effects
chemical_list: D009153:Mutagens; D005020:Ethyl Methanesulfonate