Gastrointestinal complications associated with pelvic exenteration.
Between October, 1969, and August, 1981, 125 pelvic exenterations were performed by gynecologic oncologists at the University of Alabama in Birmingham. One hundred twenty patients underwent an exenterative procedure that required urinary diversion and a gastrointestinal anastomosis. Gastrointestinal complications accounted for 60% of all nonmalignant indications for reoperation after exenteration. The common factor in the majority of gastrointestinal complications was the presence of an anastomosis in previously irradiated small bowel. Other preoperative factors, such as significant medical disease, previous laparotomy, or malnutrition, had little apparent effect on the rate of gastrointestinal complications. Avoidance of a small bowel anastomosis by means of a colon conduit, use of an omental pedicle to bring new blood supply into the pelvis, and hyperalimentation have reduced the risk of small bowel obstruction and fistula to 2.2%, while alteration in surgical technique has decreased the rectovaginal fistula rate to 5.3%.
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005747:Gastric Fistula / Q000209:etiology / Q000601:surgery; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006801:Humans; D007412:Intestinal Fistula / Q000209:etiology / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010385:Pelvic Exenteration / Q000009:adverse effects*; D011183:Postoperative Complications; D011379:Prognosis; D012006:Rectovaginal Fistula / Q000209:etiology / Q000601:surgery; D012086:Reoperation; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000601:surgery*