title: [Radiation and combination treatment of breast cancer metastases to the lungs].
abstract: The authors describe methodological and clinical results of the so-called large field irradiation of 56 patients with breast cancer metastases to the lungs. Of these, 46 received radiotherapy alone, 10 radiotherapy in combination with polychemotherapy using the CMF scheme (cyclophosphamide, methotrexate and 5-fluorouracil). As a result of radiotherapy (46 women), a noticeable objective response was achieved in 44% of the cases; among 10 patients on multimodality therapy it was achieved in 4. Average remission was 9 mos. in the 1st group and 8 mos. in the 2nd group. The patients were treated in the outpatient department. Proceeding from our experience radio- and multimodality therapy can be used as conservative therapy for patients with breast cancer metastases to the lungs.
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D013997:Time Factors
chemical_list: D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Luchevoe i kompleksnoe lechenie metastazov raka molochnoĭ zhelezy v legkie.