[In vitro antibacterial activity of eight third generation cephalosporins (author's transl)].
This work report a study of antibacterial activity of eight third generation cephalosporins : cefotaxime, moxalactam, cefoperazone, cefotiam, ceftazidime, ceftriaxone, cefmenoxime and cefotetan. The essential interest of these antibiotics is their activity against Enterobacteriaceae resistant to cefalothin ; however, five of them are clearly superior ; cefotaxime, moxalactam, cefmenoxime, ceftriaxone and ceftazidime. Ceftazidime is the best against Pseudomonas aeruginosa and moxalactam against the Bacteroides group. Against others bacterial groups, these new cephalosporins are not superior to former products.
D000150:Acinetobacter / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects; D006190:Haemophilus / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
D002511:Cephalosporins
Activité cantibactérienne in vitro de huit céphalosporines de troisième génération.