title: Decreased plasma motilin concentrations in pregnancy.
abstract: Plasma motilin concentrations were measured in 37 women during the second and third trimester of pregnancy and one week after delivery. The mean plasma motilin concentrations, both fasting and after a glucose load and a mixed meal, were significantly (p less than 0.001) reduced during pregnancy, returning to the normal range one week post partum. Pregnancy appears to have a profound inhibitory effect on plasma motilin, and this may in part be responsible for the gastrointestinal hypomotility associated with pregnancy.
mesh_terms: D005260:Female; D005768:Gastrointestinal Hormones / Q000097:blood*; D005951:Glucose Tolerance Test; D006801:Humans; D009037:Motilin / Q000097:blood*; D049590:Postpartum Period; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third
chemical_list: D005768:Gastrointestinal Hormones; D009037:Motilin