title: Computer analysis of Tc-99m DPD and Tc-99m MDP kinetics in humans: concise communication.
abstract: Technetium-99m DPD and Tc-99m(Sn)MDP were compared regarding the quality of skeletal images and the compartmental kinetic data, in two groups of nine normal subjects. No difference in scan quality was found. Data derived from compartmental kinetic analysis suggest that MDP has a higher bone uptake and a lower soft-tissue retention in comparison with DPD.
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D003201:Computers; D004164:Diphosphonates / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D008954:Models, Biological; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D013667:Technetium / Q000378:metabolism*; D013669:Technetium Tc 99m Medronate
chemical_list: D004164:Diphosphonates; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid; C023568:technetium Tc 99m (Sn)methylenediphosphonate; D013667:Technetium; D013669:Technetium Tc 99m Medronate