title: Vertebrate skin type I collagen: comparison of bony fishes with lamprey and calf.
abstract: 1. Characterization of Type I collagen alpha chains, alpha 1 and alpha 2, in the skin tissues of carp and common mackerel revealed a marked interspecies difference in CNBr-peptide maps of the alpha 2 chains, suggesting the hypervariability during evolution of the alpha 2 chains relative to the alpha 1 chains. 2. When compared with calf Type I collagen, lower vertebrate Type I collagens derived from these bony fishes as well as from lamprey were found to exhibit a higher degree of structural similarity between their alpha 1 and alpha 2 chains.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D003094:Collagen / Q000032:analysis*; D005399:Fishes / Q000378:metabolism*; D007798:Lampreys / Q000378:metabolism*; D012867:Skin / Q000032:analysis*; D013045:Species Specificity
chemical_list: D000596:Amino Acids; D003094:Collagen