Pargyline-induced mania in primary affective disorder: case report.
A case is described of a 47-year-old man who developed a manic psychosis while receiving pargyline treatment for concurrent depression and hypertension. The pharmacologic actions of pargyline are discussed with regard to its partial selectivity for MAO-B and presumed action in dopamine systems, and clinicians are alerted to this uncommon drug reaction.
D000341:Affective Disorders, Psychotic / Q000139:chemically induced*; D001714:Bipolar Disorder / Q000139:chemically induced*; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010293:Pargyline / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use
D010293:Pargyline