Proliferation of fibroblast-like cells on failing intraocular lenses.
The process of reactivation and multifocal proliferation of fibroblast-like cells near giant cells on the surface of a well-developed cellular membrane covering a Choyce anterior chamber lens implant is described histologically in an eye that had a good surgical result at first and later developed bullous keratopathy, corneal ulceration, and final rupture three years following surgery. This is compared with another eye with a late stage of scar-formation surrounding a Choyce implant two and a half years after implantation with severe complications. Details of lens implant cytology are demonstrated and discussed.
D000368:Aged; D003316:Corneal Diseases / Q000150:complications / Q000473:pathology; D003320:Corneal Ulcer / Q000150:complications; D004868:Equipment Failure; D005347:Fibroblasts / Q000166:cytology* / Q000473:pathology; D006644:Histiocytes / Q000166:cytology; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male