Histological examination of the effect of differently fractionated irradiations on transplanted mouse-tumours. II. Observations with Harding-Passey melanoma.
Comparing the histological effects of differently fractionated X-ray irradiations, using always the same total dose, it seems that Harding-Passey melanoma suffers in the early time points more severe damage by relatively high radiation fractions given with 3 to 4 day intervals than from daily applied smaller fractions of radiation. The daily several times given ultra-fractionation may promote the tumour destroying effect of X-ray irradiation from some points of view.
D000818:Animals; D002467:Cell Nucleus / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects; D008297:Male; D008545:Melanoma / Q000532:radiotherapy*; D051379:Mice; D008938:Mitosis / Q000528:radiation effects; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000532:radiotherapy; D011879:Radiotherapy Dosage