4-Aminopyridine and fiber potentials in rat and human hippocampal slices.
Compound fiber action potentials of stratum radiatum afferents in slices from human and rat hippocampus are shown to be prolonged by 4-aminopyridine (4-AP). This action can explain the enormous increase in synaptic transmitter release caused by 4-AP.
D015761:4-Aminopyridine; D000200:Action Potentials / Q000187:drug effects; D000631:Aminopyridines / Q000494:pharmacology*; D000818:Animals; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D051381:Rats; D013569:Synapses / Q000502:physiology
D000631:Aminopyridines; D015761:4-Aminopyridine