Liquid chromatographic analysis of samples containing cocaine, local anesthetics, and other amines.
A liquid chromatographic procedure is described for the separation of cocaine, local anesthetics, and other amines often encountered in cocaine look-alike preparations. Amines such as ephedrine, pseudoephedrine, and phenylpropanolamine are identified following derivatization with phenylisothiocyanate. The isocratic, reverse phase method uses dual wavelength detection at 254 and 280 nm.
D000588:Amines / Q000032:analysis*; D000779:Anesthetics, Local / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D003042:Cocaine / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D000588:Amines; D000779:Anesthetics, Local; D003042:Cocaine