title: Clinical pharmacology of diuretics.
abstract: Diuretics belong to the drugs most frequently used. Thiazide diuretics, loop diuretics and potassium sparing diuretics are the agents with practical significance. Many data concerning the pharmacokinetics of these drugs have been reported. Nevertheless, the metabolism of some diuretics is not yet fully elucidated. There are numerous pharmacodynamic drug interactions with diuretics which in general can be predicted from the spectrum of pharmacodynamic actions of the drugs involved.
mesh_terms: D002191:Canrenoic Acid / Q000378:metabolism; D002192:Canrenone / Q000378:metabolism; D004232:Diuretics / Q000009:adverse effects / Q000378:metabolism*; D004976:Ethacrynic Acid / Q000378:metabolism; D006801:Humans; D006852:Hydrochlorothiazide / Q000378:metabolism; D007408:Intestinal Absorption; D007700:Kinetics; D011485:Protein Binding; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects / Q000378:metabolism*; D013148:Spironolactone / Q000378:metabolism
chemical_list: D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D006852:Hydrochlorothiazide; D013148:Spironolactone; D002192:Canrenone; D002191:Canrenoic Acid; D004976:Ethacrynic Acid