[Aerobic and anaerobic microflora in experimental drug-induced enterocolitis].
The results of studying aerobic and anaerobic intestinal microflora of rabbits with experimental enterocolitis caused by administration of 7-chlor-7-desoxylincomycin are presented. An increased number of E. coli and some other gram-negative bacteria was noted. It was shown that the quantitative and qualitative composition of the obligate anaerobic microflora was changed: the number of cells of the bacteroids, bifidobacteria, peptococci and peptostreptococci resistant to the antibiotic was low, but the number of clostridia cells resistant to the antibiotic was high. On the basis of a thorough investigation the latter cultures were classified as belonging to Cl. butyricum.
D000332:Aerobiosis; D000693:Anaerobiosis; D000818:Animals; D001419:Bacteria / Q000302:isolation & purification*; D002981:Clindamycin / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced / Q000382:microbiology*; D004751:Enteritis / Q000139:chemically induced / Q000382:microbiology*; D007422:Intestines / Q000382:microbiology; D011817:Rabbits; D013997:Time Factors
D002981:Clindamycin
Aérobnaia i anaérobnaia mikroflora pri éksperimental'nom lekarstvennom énterokolite.