title: [Optimal inoculation doses of meningococcal chemical polyvalent ABC vaccine for immunizing children of various ages and adolescents. I. Safety and reactogenicity of different dosages of the preparation].
abstract: The investigation was carried out to study the safety and reactogenicity of meningococcal chemical polyvalent (ABC) vaccine with the aim of finding the optimum vaccination doses of this vaccine for the immunization of children of different age groups. The investigation, carried out in accordance with the methodological principles of a strictly controlled epidemiological field trial, showed the preparation to be safe, nonreactogenic and to produce no pronounced sensitizing effect.
mesh_terms: D000293:Adolescent; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology; D001831:Body Temperature / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009345:Neisseria meningitidis / Q000276:immunology*; D013997:Time Factors
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Optimal'nye privivochnye dozy meningokokkovoĭ khimicheskoĭ polivalentnoĭ ABC-vaktsiny dlia immunizatsii deteĭ razlichnogo vozrasta i podrostkov. Soobshchenie I. Bezvrednost' i reaktogennost' razlichnykh dozirovok preparata.