title: Electromagnetic stimulation of ligament healing in rabbits.
abstract: To evaluate the effect of a specific noninvasive method of electrical stimulation on ligament healing in rabbits, a solid core electromagnet energized by a square wave unidirectional current was applied to injured and repaired medial collateral ligaments seven hours per day, five days per week for intervals of up to six weeks. Healing was evaluated by gross, histologic, biochemical, and biomechanical parameters. Stimulation was shown to increase histologic maturity relatively, restore stiffness and failure strength earlier, and return collagen content toward normal unoperated values sooner in these healing ligaments. It is uncertain whether the end point of healing is affected by this technique, but at six weeks both histologic and biochemical evidence of acceleration remains. Further investigation into the effect of electromagnetic stimulation by this and other fields on non-osseous tissues and their components is indicated.
mesh_terms: D000818:Animals; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D008023:Ligaments, Articular / Q000502:physiology / Q000528:radiation effects*; D008297:Male; D011817:Rabbits; D011840:Radiation, Nonionizing; D013718:Tensile Strength; D013997:Time Factors; D014945:Wound Healing / Q000528:radiation effects*