[Comparative evaluation of the hypoglycemic effect of the 2d-generation sulfonylurea preparations maninil and diamicron in diabetes mellitus].
Glycemia level and diurnal glucosuria were studied in the morning, afternoon and evening in a group of 27 patients with insulin-dependent diabetes mellitus before and after diamicron therapy for 1.5 to 3 months. A similar investigation was performed in a group of 20 patients, suffering from diabetes mellitus of the second type before and following maninil treatment during 1.5 to 2 months. It was shown that diamicron exerts a more pronounced sugar-lowering effect in comparison with that of maninil. It promotes stable glycemia development and should take an appropriate place among hypoglycemics used now in diabetology.
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000378:metabolism; D004341:Drug Evaluation; D005907:Gliclazide / Q000627:therapeutic use*; D005905:Glyburide / Q000627:therapeutic use*; D006029:Glycosuria / Q000652:urine; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008875:Middle Aged; D013453:Sulfonylurea Compounds / Q000627:therapeutic use*; D013607:Tablets
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D013607:Tablets; D005907:Gliclazide; D005905:Glyburide
Sravnitel'naia otsenka gipoklikemiziruiushchego éffekta preparatov sul'fonilmocheviny vtorogo pokoleniia maninila i diamikrona u bol'nykh sakharnym diabetom.