title: [Cytochemical changes in the peripheral blood leukocytes of guinea pigs inoculated against plague, tularemia and anthrax].
abstract: The immunization of guinea pigs with trivaccine and monovaccines against plaque, tularemia and anthrax induces a decrease in the activity of acidic phosphatase in lymphocytes, as well as a decrease in the number of lymphocytes containing this enzyme. A decrease in the activity of alkaline phosphatase and peroxidase had been found to occur in neutrophil leukocytes. Besides, neutrophil leukocytes have shown an increase in the activity of acidic phosphatase and nonspecific esterases. The study based on the evaluation of the activity of the above-mentioned enzymes in lymphocytes and neutrophils has not revealed the predominant influence exercised by any of the antigens, different in their nature and used separately or in the form of a combined preparation, on immunogenesis.
mesh_terms: D000818:Animals; D000881:Anthrax / Q000201:enzymology* / Q000276:immunology; D001408:Bacillus anthracis / Q000276:immunology; D001428:Bacterial Vaccines / Q000008:administration & dosage; D005604:Francisella tularensis / Q000276:immunology; D006168:Guinea Pigs; D006651:Histocytochemistry; D007109:Immunity; D007962:Leukocytes / Q000201:enzymology* / Q000276:immunology; D010930:Plague / Q000201:enzymology* / Q000276:immunology; D010931:Plague Vaccine / Q000008:administration & dosage; D013997:Time Factors; D014406:Tularemia / Q000201:enzymology* / Q000276:immunology
chemical_list: D001428:Bacterial Vaccines; D010931:Plague Vaccine
vernacular_title: Tsitokhimicheskie izmeneniia v leĭkotsitakh perifericheskoĭ krovi u morskikh svinok, privitykh protiv chumy, tuliaremii i sibirskoĭ iazvy.