Haemodynamics in microarterial stenosis: an experimental study in rats using the Doppler technique.
Little is known about the effects of stenosis on the blood flow in small arteries. The purpose of this study was to determine the critical stenosis in the rat aorta. Artificial stenoses were deliberately created in the aorta and the influence on the blood flow through the femoral arteries was measured using a non-invasive Doppler technique. The degree of stenosis was assessed by microarteriographic and casting techniques. The use of the Doppler device proved to be a simple and reliable technique and the critical stenosis level was found to be 40%. In cases of severe stenosis an increase in the collateral circulation was seen.
D000818:Animals; D001018:Aortic Diseases / Q000503:physiopathology; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D006439:Hemodynamics; D051381:Rats; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow; D014463:Ultrasonography