title: Rifampin prophylaxis against H. flu type b spread - is it valid?
abstract: H. influenzae can cause not only meningitis in children but epiglottitis, cellulitis, pneumonia, pericarditis, and bacteremia. It is possible to radically reduce, if not abolish, the spread of this pathogen. But effective prophylaxis requires answers to questions of practicability relative to the availability, cost, and logistics of administering rifampin to contacts, as has been recommended.
mesh_terms: D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000382:microbiology*; D002481:Cellulitis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004825:Epiglottis / Q000382:microbiology; D005260:Female; D006192:Haemophilus Infections / Q000150:complications / Q000517:prevention & control* / Q000635:transmission; D006193:Haemophilus influenzae / Q000145:classification; D006801:Humans; D007223:Infant; D008583:Meningitis, Haemophilus / Q000517:prevention & control; D010493:Pericarditis / Q000209:etiology; D011014:Pneumonia / Q000209:etiology; D011247:Pregnancy; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use*; D018805:Sepsis / Q000209:etiology; D014295:Trimethoprim / Q000627:therapeutic use
chemical_list: D014295:Trimethoprim; D012293:Rifampin