title: Spore differentiation in relation to certain antibiotics in the blue-green alga Nodularia spumigena Mertens.
abstract: Induction of spore differentiation is achieved within three days in Nodularia spumigena by incubating the cultures at 35 degrees C in the light. Morphologically detectable sporulation and spore germination could not occur in the presence of chloramphenicol, streptomycin and penicillin. But chloramphenicol-supplemented cultures developed prominent cyanophycin granules. Synthesis of these granules seems to be a non-ribosomal phenomenon.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002454:Cell Differentiation / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology; D000458:Cyanobacteria / Q000187:drug effects / Q000502:physiology*; D010406:Penicillins / Q000494:pharmacology; D013170:Spores / Q000187:drug effects / Q000502:physiology; D013307:Streptomycin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D002701:Chloramphenicol; D013307:Streptomycin