title: Signet-ring cell lymphoma.
abstract: In a small cleaved, follicular center cell (poorly differentiated) lymphoma the majority of the cells appeared vacuolated by light microscopy. This is an example of the recently described signet-ring cell lymphoma. Immunoperoxidase staining demonstrated that the cells contained IgG/k. Ultrastructural observations indicated that small vacuoles coalesce to form the large vacuoles, which contain microvesicles approximately 50 nm in diameter.
mesh_terms: D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008223:Lymphoma / Q000473:pathology*; D008875:Middle Aged
chemical_list: D007145:Immunoglobulin kappa-Chains