title: [Bacillus subtilis var. amyloliquefaciens biosynthesis of extracellular protease possessing coagulase activity and formed under conditions of limiting the nitrogen sources in the medium].
abstract: An exocellular protease having the activity of coagulase was synthesized by Bacillus subtilis var. amyloliquefaciens when the growth medium contained no nitrogen sources. The removal of a nitrogen source from the medium was found to induce the synthesis of exoproteases by washed bacterial cells. Protein as a sole source of nitrogen in the medium inhibited rather than induced the biosynthesis of proteases possessing the activity of coagulase by the cells. The production of exoproteases with the coagulase activity was inhibited when a mixture of amino acids was used as a sole nitrogen source.
mesh_terms: D001412:Bacillus subtilis / Q000201:enzymology*; D003030:Coagulase / Q000096:biosynthesis*; D003470:Culture Media / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D009584:Nitrogen / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000096:biosynthesis*
chemical_list: D003030:Coagulase; D003470:Culture Media; D010447:Peptide Hydrolases; D009584:Nitrogen
vernacular_title: Biosintez Bacillus subtilis var. amyloliquefaciens vnekletochnoĭ proteazy, obladaiushcheĭ koagulaznoĭ aktivnost'iu i obrazuemoĭ v usloviiakh limitatsii sredy istochnikami azota.