[Mitogenic action of Mycoplasma arthritidis on the lymphoid cells of rats].
Proliferation of rat splenocytes was studied under the conditions of Mycoplasma infection in vitro. M. arthritidis in doses less than 10(7) CFU/ml exhibited a mitogenic action which seemed likely to be associated with Mycoplasma-produced factor. In higher doses M. arthritidis suppressed blast transformation caused by non-specific mitogens.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D005856:Germ-Free Life; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D008934:Mitogens / Q000494:pharmacology*; D009174:Mycoplasma / Q000472:pathogenicity*; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains; D013154:Spleen / Q000187:drug effects
D008934:Mitogens
Mitogennoe deĭstvie Mycoplasma arthritidis na limfoidnye kletki krys.