title: Arginine uptake by chick kidney mitochondria.
abstract: Arginine uptake by kidney mitochondria in two strains of chicks of high (HA) and low (LA) requirement of dietary arginine was studied by using an ion-exchange method. Dietary factors influencing uptake of arginine were also investigated. The results indicate that arginine uptake by kidney mitochondria of HA chicks was significantly higher than the LA chicks when arginine-deficient diet or diet with excess lysine was fed. The arginine uptake by kidney mitochondria reflects the kidney arginase activity. Both arginase activity and arginine uptake inversely correlated with growth rate of the two strains of chicks. However, the dietary factors that affect kidney mitochondria arginase activity are not completely parallel to the uptake of arginine by kidney mitochondria. A system that facilitates entry of arginine into kidney mitochondrial membrane is suggested.
mesh_terms: D000818:Animals; D001119:Arginase / Q000378:metabolism; D001120:Arginine / Q000008:administration & dosage / Q000378:metabolism*; D002645:Chickens / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000378:metabolism*; D008239:Lysine / Q000008:administration & dosage / Q000378:metabolism; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D009751:Nutritional Requirements; D013045:Species Specificity
chemical_list: D001120:Arginine; D001119:Arginase; D008239:Lysine