title: Development of sleep-waking temporal sequencing in infants at risk for the Sudden Infant Death Syndrome.
abstract: The periodic organization of waking, quiet sleep, and active sleep was studied in control infants and siblings of victims of the Sudden Infant Death Syndrome. Spectral estimates of all-night binary state time series recorded at 1 week and 1, 2, 3, 4, and 6 months of age revealed disturbed patterns of sleep states, especially in active sleep, from as early as the first week of life. These disruptions continued until at least 6 months of age. These data support the contention that the temporal patterning of sleep state can be used as an important neurologic marker for development.
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012306:Risk; D012894:Sleep Stages / Q000502:physiology*; D013398:Sudden Infant Death / Q000503:physiopathology*; D013997:Time Factors