title: Erythrocyte manganese concentration in healthy Japanese children, adults, and the elderly, and in cord blood.
abstract: This study showed differences in erythrocyte manganese concentrations in different age groups and in cord blood. All determinations were performed with a flameless atomic absorption spectrophotometer. The mean erythrocyte manganese concentration at one month of age was 435.1 +/- 118.7 ng/g Hb, three to four times higher than in adults. Thereafter, it decreased rapidly and was constant from 4 months to 11 yr of age. However, at 12 to 19 yr of age the concentration in males decreased (108.1 +/- 20.2 ng/g Hb) and was significantly lower than in females (141.7 +/- 25.5 ng/g Hb) (p less than 0.01). This sex difference became even greater in adults aged 20 to 40 yr, when it was 91.5 +/- 22.4 ng/g Hb in males and 141.2 +/- 19.8 ng/g Hb in females (p less than 0.001). The erythrocyte manganese concentration in adults was 31.6 +/- 9.2 ng/ml, somewhat higher than the value previously reported, which may reflect dietary habits in Japan or a racial difference.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007564:Japan; D008297:Male; D008345:Manganese / Q000097:blood*; D012737:Sex Factors; D013054:Spectrophotometry, Atomic
chemical_list: D008345:Manganese