title: The role of trauma in the spreading weals of hereditary angio-oedema.
abstract: Twenty patients with hereditary angio-oedema (HAO) were regularly observed. Trauma often initiates the swellings of HAO which, once formed, may continue to spread. In the prodromal rash too, a narrow band of weals spreads out from a central point, which often corresponds to a site of trauma e.g. a pin prick. The relationship of these observations to the role of trauma in the initiation and spread of weals in other forms of urticaria is discussed.
mesh_terms: D000328:Adult; D000799:Angioedema / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000293:injuries* / Q000473:pathology