Ultrastructure of skin in erythema nodosum leprosum.
The ultrastructural changes observed in erythema nodosum leprosum lesions were gross damage to blood vessels, particularly the endothelial cells, and deposition of immune complexes in vessel walls. Infiltrating cells and alteration of the ground substance formed a constant feature of the reaction. These changes are characteristic of an immune complex reaction.
D001808:Blood Vessels / Q000648:ultrastructure; D004727:Endothelium / Q000648:ultrastructure; D004893:Erythema Nodosum / Q000473:pathology*; D006801:Humans; D007918:Leprosy / Q000473:pathology*; D008854:Microscopy, Electron; D009504:Neutrophils / Q000648:ultrastructure; D012867:Skin / Q000648:ultrastructure*