title: Hydrolytic enzyme activities, mainly from lysosomal localization, in sera from patients who ingested a toxic oil.
abstract: Some hydrolytic enzyme activities, mainly typical of lysosomal localization, have been determined in blood sera from patients who ingested a rapeseed oil (denatured with anilines and treated by a thermal process), and in healthy subjects. beta-N-Acetylglucosaminidase, beta-D-glucosidase, beta-D-glucuronidase, alpha-L-fucosidase and leucine aminopeptidase activities were significantly higher when compared with controls (p less than 0.001); higher activities but not significant (p less than 0.2) differences were found for alpha-D-mannosidase and alkaline phosphatase. In contrast, beta-D-galactosidase, alpha-D-galactosidase, acid phosphatase and lipase showed lower activities than controls. The significance of these results is discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005229:Fatty Acids, Monounsaturated; D005506:Food Contamination; D006026:Glycoside Hydrolases / Q000097:blood; D006801:Humans; D006867:Hydrolases / Q000097:blood*; D008247:Lysosomes / Q000201:enzymology*; D008875:Middle Aged; D009821:Oils / Q000506:poisoning*; D010938:Plant Oils; D000074262:Rapeseed Oil
chemical_list: D005229:Fatty Acids, Monounsaturated; D009821:Oils; D010938:Plant Oils; D000074262:Rapeseed Oil; D006867:Hydrolases; D006026:Glycoside Hydrolases