title: Detection of acute myocardial infarction in spontaneously hypertensive rats by 99mTc-pyrrolidino methyl tetracycline.
abstract: The myocardial infarct induced by isoproterenol in spontaneously hypertensive rats accumulates higher activities of 99mTc-PM tetracycline compared with the cardiac infarct in normotensive rats caused by the same method. The isoproterenol model of the myocardial necrosis was induced in intact rats without opening the thorax and is a convenient method for experimental radioisotope studies.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D006973:Hypertension / Q000000981:diagnostic imaging*; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced / Q000000981:diagnostic imaging*; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D051381:Rats; D011919:Rats, Inbred Strains; D012382:Rolitetracycline; D013667:Technetium
chemical_list: D015609:Organotechnetium Compounds; C037308:technetium Tc 99m rolitetracycline; D013667:Technetium; D012382:Rolitetracycline; D007545:Isoproterenol