Effect of in-utero exposure to diethylstilbestrol on age at onset of puberty and on postpubertal hormone levels in boys.
A group of boys exposed to diethylstilbestrol (DES) in utero who had earlier been found to have urogenital abnormalities were studied for evidence of later effects of DES on their health, physical development and hormonal status. They showed no difference in age at onset of puberty, development of sexual characteristics or hormone levels from boys of the same age who had not been exposed to DES. However, the exposed group tended to have smaller testes.
D000293:Adolescent; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011627:Puberty / Q000187:drug effects*; D013737:Testis / Q000187:drug effects
D012739:Gonadal Steroid Hormones; D004054:Diethylstilbestrol