title: [Incidence of primary toxoplasmosis infection in pregnant women].
abstract: Toxoplasma-specific antibodies transferred across the placenta were determined in 1953 blood samples of newborn infants from the Lower Saxony newborn-screening-laboratory using the indirect immunofluorescence test. There were no antibodies demonstrable in 54.4% of the samples. Related to the age of the mothers there was increase of positive findings of about 1% per year. Among 10 000 pregnancies about 70 to 80 mothers can be expected to undergo a primary infection with Toxoplasma gondii. With a fetal infection rate of about 50% derived from the literature 30 to 40 cases of congenital toxoplasmosis of variable severity, three among them serious, may be expected.
mesh_terms: D000906:Antibodies / Q000032:analysis; D005260:Female; D005860:Germany, West; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000276:immunology; D012306:Risk; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology; D014125:Toxoplasmosis, Congenital / Q000453:epidemiology / Q000276:immunology
chemical_list: D000906:Antibodies
vernacular_title: Häufigkeit der Toxoplasmose-Erstinfektion bei Schwangeren.