[Combined effect of ethonium and antibiotics on Pseudomonas aeruginosa].
The combined effect of ethonium and 5 antibiotics belonging to different groups was studied with 30 clinical strains of P. aeruginosa. A 2--8-fold increase in the activity of kanamycin and tetracycline against some strains was observed. The MIC of carbenicillin, polymycin M and cefotaxime was lowered by 2--6 times and with respect to some strains by 16--32 times. The detergent is recommended to be used in combination with some antibiotics in treatment of infections caused by resistant strains of P. aeruginosa.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004357:Drug Synergism; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000644:Quaternary Ammonium Compounds; C004921:Ethonium
Kombinirovannoe deĭstvie étoniia s antibiotikami na Pseudomonas aeruginosa.