Mucosal bridges of the upper esophagus after radiotherapy for Hodgkin's disease.
A 47-yr-old man presented with dysphagia 4 yr after mediastinal radiotherapy for Hodgkin's disease. X-ray series, fiberoptic endoscopy, and computerized transverse tomography showed mucosal bridges in the upper esophagus. Histologically, these bridges were constituted from normal epithelium overlying a chronic inflammatory lamina propria, without evidence of Hodgkin's disease recurrence or of squamous cell carcinoma. Swallowing was improved by endoscopic electrocoagulation and Eder-Puestow dilatations. Several arguments favor the hypothesis that these mucosal bridges were the late sequelae of radiation esophagitis.
D003680:Deglutition Disorders / Q000209:etiology; D004947:Esophagus / Q000528:radiation effects*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000532:radiotherapy*; D008875:Middle Aged; D009092:Mucous Membrane / Q000528:radiation effects; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors