Co2+ and Mn2+ uptake by crab nerve fibers in resting state and potassium depolarization.
Transition metal ions, Mn2+ and Co2+, are incorporated into nerve fibers when they are applied externally. For nerve fibers in the resting state, however, extracellular and intracellular water may be distinguished by applying transition metal ions externally. NMR spectra of water protons from nerve fibers in high potassium media, which contain transition metal ions, consist of three or more components, reflecting a complex distribution of these ions around the nerve membranes. In the case of Co2+, three components may be identified.
D000818:Animals; D003386:Brachyura; D003035:Cobalt / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000378:metabolism*; D009412:Nerve Fibers / Q000378:metabolism*; D011188:Potassium / Q000494:pharmacology*; D013997:Time Factors; D014867:Water
D014867:Water; D003035:Cobalt; D008345:Manganese; D011188:Potassium