Altered brainstem structure of spontaneously hypertensive (SHR) rats.
Computerized morphometric analysis of soma cross-sectional areas of single neurons in selected brainstem nuclei revealed that significant structural differences exist between spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats. Neuronal sizes were significantly reduced in 5 of 9 brainstem regions of SHR's compared to WKY rats. Differences in cell densities were also found.
D000344:Afferent Pathways / Q000033:anatomy & histology; D000818:Animals; D001794:Blood Pressure; D001933:Brain Stem / Q000033:anatomy & histology*; D002452:Cell Count; D008297:Male; D009474:Neurons / Q000648:ultrastructure; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains