title: Regulation of immunity in rats by lactogenic and growth hormones.
abstract: Antibody formation to sheep red blood cells and the development of contact dermatitis in response to dinitrochlorobenzene are impaired in hypophysectomized (Hypo-X) rats. Rat prolactin, rat growth hormone, bovine prolactin, bovine growth hormone, human placental lactogen and human growth hormone all restored the immunological competence of Hypo-X animals. The possible mechanism of action of these hormones on immune reactions is discussed.
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D003877:Dermatitis, Contact / Q000276:immunology; D004137:Dinitrochlorobenzene; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D007016:Hypophysectomy; D007111:Immunity, Cellular / Q000187:drug effects*; D010928:Placental Lactogen / Q000494:pharmacology*; D011388:Prolactin / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011920:Rats, Inbred WF
chemical_list: D004137:Dinitrochlorobenzene; D011388:Prolactin; D013006:Growth Hormone; D010928:Placental Lactogen