[Characteristics of membrane and plasma proteins in the spontaneously hypertensive rat].
The red blood cell membrane proteins and plasma proteins of normal and spontaneous hypertensive Rats were studied by uni- and bidimentional polyacrylamide gel electrophoresis. The amount of band 3 was observed to be significantly reduced in the red blood cell membrane of spontaneously hypertensive Rats. Plasma from these Rats contained two additional heatstable proteins, characterized by a molecular weight of 16,000 dalton and isoelectric points of 4.7 and 5.1. These changes may constitute biochemical changes genetically associated with hypertension.
D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte; D001798:Blood Proteins / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006973:Hypertension / Q000097:blood*; D008297:Male; D008565:Membrane Proteins / Q000097:blood*; D008970:Molecular Weight; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D001457:Anion Exchange Protein 1, Erythrocyte; D001798:Blood Proteins; D008565:Membrane Proteins
Particularités protéiques des membranes et du plasma chez le Rat spontanément hypertendu.