Calcium-dependent and calcium-independent aggregation of established and malignant cell lines.
EGTA dissociated cell lines could be distinguished on the basis of their dependence on calcium during initial aggregation. However, the calcium-dependent aggregation could not be abolished by low chymotrypsin/EGTA treatment. These differences were not related to any morphogenetic property of the cells and suggest that different aggregation mechanisms are involved.
D000818:Animals; D002118:Calcium / Q000502:physiology*; D002448:Cell Adhesion; D002449:Cell Aggregation / Q000187:drug effects*; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology; D002471:Cell Transformation, Neoplastic; D002918:Chymotrypsin / Q000494:pharmacology; D004285:Dogs; D004533:Egtazic Acid / Q000494:pharmacology*; D005026:Ethylene Glycols / Q000494:pharmacology*; D006801:Humans
D005026:Ethylene Glycols; D004533:Egtazic Acid; D002918:Chymotrypsin; D002118:Calcium