title: Splenic variations affecting sarcomagenesis among mice of an inbred strain.
abstract: Among overtly identical mice of an inbred strain, some are relatively susceptible and some relatively resistant to sarcomagenesis by large concentrations of 3-methylcholanthrene (MCA) (Prehn, 1975 a). Spleen cells from mice, subsequently shown to be relatively susceptible, conveyed a relative resistance to oncogenesis when transferred to irradiated recipients; spleen cells from mice, subsequently shown to be relatively resistant, conveyed to secondary hosts a relative susceptibility.
mesh_terms: D000818:Animals; D008297:Male; D008748:Methylcholanthrene; D051379:Mice; D008809:Mice, Inbred C3H / Q000276:immunology*; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000139:chemically induced* / Q000276:immunology; D013154:Spleen / Q000166:cytology / Q000276:immunology*
chemical_list: D008748:Methylcholanthrene