title: Tularemia complicated by acute renal failure.
abstract: Acute renal failure has been a rare, uniformly fatal complication of infection with Francisella tularensis. The literature suggests that either acute tubular necrosis, interstitial nephritis, or glomerulonephritis may be responsible for this syndrome. We have described a patient with tularemia who had nonoliguric acute renal failure probably due to interstitial nephritis and who recovered slowly but spontaneously during antimicrobial therapy with doxycycline.
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology*; D000368:Aged; D002555:Cerebrospinal Fluid / Q000032:analysis; D004318:Doxycycline / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009393:Nephritis / Q000188:drug therapy / Q000209:etiology; D014406:Tularemia / Q000150:complications* / Q000175:diagnosis / Q000276:immunology
chemical_list: D004318:Doxycycline