title: Pyridoxine-dependent seizures.
abstract: Pyridoxine-dependent seizures occur as a result of an increased requirement of the vitamin within the central nervous system. With early intervention, these seizures can be completely controlled by continued administration of pharmacologic doses of the vitamin. Without prompt treatment, continued seizures and irreversible neurologic damage result. This disorder should be considered in any infant with seizures that are hard to control.
mesh_terms: D004569:Electroencephalography; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology; D008297:Male; D011736:Pyridoxine / Q000502:physiology* / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D026681:Vitamin B 6 Deficiency / Q000150:complications; D005680:gamma-Aminobutyric Acid / Q000502:physiology
chemical_list: D005680:gamma-Aminobutyric Acid; D011736:Pyridoxine