Serum LH and FSH levels in women with polycystic ovary syndrome before and after ovarian wedge resection.
Serum LH and FSH concentrations were examined by radioimmunoassay in 41 women with polycystic ovary syndrome before and after ovarian wedge resection. Serum LH level was nearly threefold that of normal control patients, while that of FSH was decreased. Serum LH value decreased. Serum LH value decreased significantly after ovarian wedge resection, but remained elevated in comparison to that of healthy women. Serum FSH concentration increased after operation to normal values. LH : FSH ratio of polycystic ovary patients was elevated in comparison to that of normal patients. After ovarian wedge resection it decreased significantly, but remained twofold that of normal healthy women. The alterations in gonadotropin secretion were related to the alterations in the steroid milieu and feedback.
D000293:Adolescent; D000328:Adult; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006728:Hormones / Q000096:biosynthesis; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood*; D010053:Ovary / Q000378:metabolism; D011085:Polycystic Ovary Syndrome / Q000601:surgery*; D011182:Postoperative Care; D011300:Preoperative Care; D011863:Radioimmunoassay
D006728:Hormones; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone