title: [Evidence and characterization of an androgen receptor in the uropygial gland of the adult male quail].
abstract: 5 alpha-DHT is bound with a high affinity (Kd = 0.8 nM) and a limited capacity (80 fmol/mg proteins) in the cytosol of the preen gland of quails, an analogue of sebaceous glands. The complex can be precipitated by protamin-sulfate and is sedimented in the 8 S region after ultra-centrifugation in a sucrose gradient. The occurrence of this binding that exhibits the main properties of an androgen receptor, supports the use of the preen gland of quails as a tool for the study of the mechanism of action of androgens in birds and as a model for the study of the androgen control of sebaceous-like glands.
mesh_terms: D000818:Animals; D003370:Coturnix; D003600:Cytosol / Q000378:metabolism; D013196:Dihydrotestosterone / Q000378:metabolism; D006120:Grooming; D007700:Kinetics; D008297:Male; D011944:Receptors, Androgen / Q000302:isolation & purification / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D012627:Sebaceous Glands / Q000378:metabolism*
chemical_list: D011944:Receptors, Androgen; D011987:Receptors, Steroid; D013196:Dihydrotestosterone
vernacular_title: Mise en évidence et caractérisation du récepteur des androgènes dans la glande uropygienne de la Caille mâle adulte.