title: Rat immunoglobulin delta heavy chain gene: nucleotide sequence derived from cloned cDNA.
abstract: Rat immunoglobulin delta heavy-chain mRNA has been isolated. RNA blot analysis revealed that this mRNA with a length of 1.8 kb encodes for the secreted form of IgD. The corresponding cDNA was cloned in plasmid pBR322 and its sequence was determined. The hybrid plasmid contains a 775-bp insert comprising a partial C delta 1 sequence and complete C delta H, C delta 3, C delta DC and 3' untranslated sequences. Rat and mouse IgD amino acid sequences show striking homology in C delta 3 and C delta DC regions.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D005796:Genes; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007138:Immunoglobulin delta-Chains / Q000235:genetics*; D051381:Rats
chemical_list: D007143:Immunoglobulin Heavy Chains; D007138:Immunoglobulin delta-Chains; D004247:DNA