A clinical experience with the NCGT graft.
A comparison of 130 grafts done in 101 patients included 47 veins, 25 Johnson & Johnson dialdehyde-starch-tanned collagen prostheses, and 58 NCGT grafts that had been followed for a 40-month period. This study had documented the fact that in spite of frequent poor runoff, a useful result is provided by the NCGT graft apparently due in part to its built-in nonthrombogenic structure providing a cumulative patency of 73%. The patency rate was even superior with venous bypasses. Therefore, we still feel that the autogenous vein provides the most useful bypass conduit available in vascular reconstruction. In situations where a vein could not be used or was not available the NCGT graft offers an equally useful nonthrombogenic surface to maintain prolonged patency. Thus, collagen appropriately modified can provide a useful prosthesis in vascular reconstruction.
D000368:Aged; D000783:Aneurysm / Q000209:etiology; D000818:Animals; D002417:Cattle; D002986:Clinical Trials as Topic; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D005976:Glutaral; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D013518:Surgery, Plastic; D014680:Veins / Q000601:surgery*
D003094:Collagen; D005976:Glutaral