Primary structure of a human lambda-chain (Weir) of the Mcg type.
The amino acid sequence of the Bence-Jones protein Weir has been determined. This lambda II protein is of the Mcg type. Since a mixed dinner of Weir and Mcg can be prepared in a form suitable for crystallographic analysis it was of interest to compare the sequences of these two lambda-chains. A total of 37 differences, which include one previously determined constant-region substitution, have been found.
D000595:Amino Acid Sequence; D001536:Bence Jones Protein; D002850:Chromatography, Gel; D006801:Humans; D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains
D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D001536:Bence Jones Protein