title: [State of oxidizing processes in rat liver in chronic heliotrine hepatitis].
abstract: Parameters of oxidative phosphorylation, the rate of respiration in various metabolic states of rat liver mitochondria as well as activity of lactate-and malate dehydrogenases in blood serum were altered in rats with chronic heliotrine hepatitis. Cupir (copper containing complex substance) normalized the enzymatic activity and improved all the energy reactions studied in mitochondria.
mesh_terms: D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism*; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008291:Malate Dehydrogenase / Q000097:blood; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D011763:Pyrrolizidine Alkaloids / Q000494:pharmacology*; D051381:Rats
chemical_list: D011763:Pyrrolizidine Alkaloids; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; C010178:heliotrine
vernacular_title: Sostoianie okislitel'nykh protsessov v pecheni krys pri khronicheskom geliotrinnom gepatite.