title: Lactic acidosis in lung cancer.
abstract: Because the liver is the dominant site of lactate clearance and utilization, extensive liver metastases may predispose the patient to the development of lactic acidosis. We have described two patients with hepatic metastatic disease who had fatal lactic acidosis. Greater awareness and prompt treatment of this frequently fatal complication may improve survival of patients with potentially treatable advanced malignancies.
mesh_terms: D000138:Acidosis / Q000209:etiology* / Q000401:mortality; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000401:mortality; D005260:Female; D006801:Humans; D007773:Lactates; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000150:complications* / Q000401:mortality; D008297:Male; D008875:Middle Aged
chemical_list: D007773:Lactates