Increased polyunsaturated fatty acids in developing and regenerating peripheral nerve.
Characteristic fatty acids of peripheral nerve myelin are mainly saturated and monounsaturated. A marked increase of polyunsaturated fatty acids, particularly arachidonic acid, was found in endoneurial phosphatidylethanolamine of both developing and regenerating rat sciatic nerve, suggesting a close association between polyunsaturated fatty acids and peripheral nerve myelination.
D000818:Animals; D000831:Animals, Newborn; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D009416:Nerve Regeneration; D019301:Oleic Acid; D009829:Oleic Acids / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000254:growth & development* / Q000502:physiology; D013329:Structure-Activity Relationship
D001095:Arachidonic Acids; D005231:Fatty Acids, Unsaturated; D009829:Oleic Acids; D010714:Phosphatidylethanolamines; D016718:Arachidonic Acid; D019301:Oleic Acid