Electrolytes and free amino acids in leg skeletal muscle of young and elderly women.
Electrolytes and/or amino acids were determined in leg skeletal muscle biopsies from elderly (age range 57-75 years) and young (age range 20-35 years) apparently healthy women. When compared to the young group, the elderly one was characterized by increased levels of muscular Na+ and Cl-, while the calculated intracellular concentration of Na+ was reduced. The pattern and levels of free amino acids showed only minor differences between elderly and young women. Intracellular Mg2+ and K+ showed a significant correlation with muscle levels of simultaneously determined energy-rich phosphagen compounds that was published previously.
D000368:Aged; D000375:Aging; D000596:Amino Acids / Q000032:analysis*; D001706:Biopsy; D004573:Electrolytes / Q000032:analysis*; D005260:Female; D006801:Humans; D007866:Leg; D008875:Middle Aged; D009132:Muscles / Q000032:analysis*
D000596:Amino Acids; D004573:Electrolytes