[Effect of tranquilizers on the course of myocardial ischemia and on myocardial resistance to hypoxia in coronary artery occlusion].
It was shown that meprobamate and phenazepam protect the myocardium from hypoxia and decrease myocardial ischemia during coronary occlusion. Phenibut and mebicar reduce the tolerance to ischemia and increase the degree of ischemic injury to the heart. Diazepam has no effect on these processes.
D000818:Animals; D002415:Cats; D003327:Coronary Disease / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D005260:Female; D006321:Heart / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D000860:Hypoxia / Q000517:prevention & control*; D008297:Male; D013997:Time Factors; D014149:Tranquilizing Agents / Q000627:therapeutic use*
D014149:Tranquilizing Agents
Vliianie trankvilizatorov na techenie ishemii miokarda i na ustoĭchivost' miokarda k gipoksii pri okkliuzii koronarnoĭ arterii.