title: Relationship between frequency of pilocarpine administration and salivary IgA level.
abstract: The effect of repetitive administration of pilocarpine nitrate on the salivary volume and salivary IgA concentration was studied in the NIH white hamster. One and one-half to three-fold increases in salivary volume, coupled with decreases of 1/3 to 2/3 in IgA concentration, occurred as the frequency of administration of pilocarpine increased.
mesh_terms: D000818:Animals; D006224:Cricetinae; D005779:Immunodiffusion; D007070:Immunoglobulin A / Q000032:analysis* / Q000378:metabolism; D010862:Pilocarpine / Q000008:administration & dosage* / Q000494:pharmacology; D012463:Saliva / Q000276:immunology; D012471:Salivary Proteins and Peptides / Q000032:analysis* / Q000378:metabolism; D012472:Salivation / Q000187:drug effects
chemical_list: D007070:Immunoglobulin A; D012471:Salivary Proteins and Peptides; D010862:Pilocarpine