Characterization and purification of fatty acid-binding protein in rat and human adipose tissue.
A protein with properties similar to fatty acid-binding protein has been isolated from rat and human adipose tissue. Comparison of fatty acid-binding protein from rat liver and adipose tissue and human adipose tissue shows that all have approximately similar molecular weights. Immunologically, rat liver fatty acid-binding protein is similar to the protein characterized from rat adipose tissue. In isolated rat fat cells the fatty acid-binding protein was demonstrated to be involved in the uptake and esterification of long-chain fatty acids. These observations constitute evidence for a potential role of this protein in the fatty acid metabolism of adipocytes.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002090:Butyrophenones / Q000494:pharmacology; D002352:Carrier Proteins / Q000302:isolation & purification / Q000378:metabolism*; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D006801:Humans; D005779:Immunodiffusion; D007700:Kinetics; D008297:Male; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins; D019308:Palmitic Acid; D010169:Palmitic Acids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D025521:Tumor Suppressor Proteins
D002090:Butyrophenones; D002352:Carrier Proteins; C107608:FABP7 protein, human; C490174:Fabp7 protein, rat; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins; D010169:Palmitic Acids; D025521:Tumor Suppressor Proteins; D019308:Palmitic Acid; C005000:flavaspidic acid