title: Changes in liver glycogen and glycolytic intermediates during abdominal surgery in man.
abstract: 1. Changes in liver glycogen and glycolytic intermediates were determined in ten patients undergoing abdominal surgery for carcinoma of the colon. 2. One hour of surgery resulted in a 19% decrease in liver glycogen, together with an increase in hepatic glucose 6-phosphate and glucose concentrations. 3. Blood glucose increased from 5.01 to 6.67 mmol/l during the hour between liver biopsies. 4. We conclude that the hyperglycaemia of surgery is associated with stimulation of hepatic glycogenolysis.
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D003110:Colonic Neoplasms / Q000601:surgery*; D006019:Glycolysis; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology; D007432:Intraoperative Period; D008099:Liver / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism*; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D008112:Liver Glycogen