Relationship between frequency of pilocarpine administration and salivary IgA level.
The effect of repetitive administration of pilocarpine nitrate on the salivary volume and salivary IgA concentration was studied in the NIH white hamster. One and one-half to three-fold increases in salivary volume, coupled with decreases of 1/3 to 2/3 in IgA concentration, occurred as the frequency of administration of pilocarpine increased.
D000818:Animals; D006224:Cricetinae; D005779:Immunodiffusion; D007070:Immunoglobulin A / Q000032:analysis* / Q000378:metabolism; D010862:Pilocarpine / Q000008:administration & dosage* / Q000494:pharmacology; D012463:Saliva / Q000276:immunology; D012471:Salivary Proteins and Peptides / Q000032:analysis* / Q000378:metabolism; D012472:Salivation / Q000187:drug effects
D007070:Immunoglobulin A; D012471:Salivary Proteins and Peptides; D010862:Pilocarpine