title: [Acute cerebral edema complicating therapy for diabetic ketoacidosis in children ].
abstract: Cerebral edema complicating treatment of diabetic ketoacidosis does not seen to be very rare. This neurologic complication, which was observed in 3 cases, presents similarly in all patients, occurs mainly in children and adolescents and is usually lethal. Its mechanism has not been clearly explained yet. Various etiologic factors have been considered; sodium depletion, rapid infusion of hypotonic solutions and rapid fall of plasma glucose level might have a deleterious effect. On the basis of these data, some preventive therapeutic measures are proposed.
mesh_terms: D001786:Blood Glucose; D001929:Brain Edema / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D016883:Diabetic Ketoacidosis / Q000150:complications* / Q000628:therapy; D005260:Female; D005440:Fluid Therapy / Q000009:adverse effects; D006801:Humans; D007010:Hyponatremia / Q000503:physiopathology; D008297:Male
chemical_list: D001786:Blood Glucose
vernacular_title: Oedème cérébral aigu compliquant le traitement de l'acido-cétose diabétique de l'enfant.