[Mutagenic effect of photoactivated methoxylated derivatives of 2-nitronaphtho (2.1-b) furan on the yeast Saccharomyces cerevisiae].
2-nitro 7-methoxy naphtho [2,1-b] furan (R 7000) and 2-nitro 8-methoxy naphtho [2,1-b] furan, which are highly mutagenic on the bacterium Salmonella typhimurium have little activity on the yeast Saccharomyces cerevisiae. Nevertheless, irradiation at 365 nm elicits a weak but significant increase of their mutagenic activity on this yeast.
D009153:Mutagens / Q000528:radiation effects; D009581:Nitrofurans / Q000528:radiation effects / Q000633:toxicity*; D010777:Photochemistry; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics; D014466:Ultraviolet Rays
D009153:Mutagens; D009581:Nitrofurans; C030911:2-nitro-7-methoxynaphtho(2-1b)furan; C011496:2-nitro-8-methoxynaphtho(2,1-b)furan
Effet mutagène sur la levure Saccharomyces cerevisiae de dérivés méthoxylés du nitro-2 naphto [2.1-b] furanne photoactivés.