[Effect of arachidonic acid on the secretion of milk caseins in vitro].
Arachidonic acid increases milk casein secretion in mammary gland slices. This stimulation is similar to prolactin stimulation. Aspirin, a prostaglandin-synthetase inhibitor, has no effect on prolactin or on arachidonic acid stimulation. Prostaglandin PGF2 alpha does not modify casein secretion. Therefore arachidonic acid stimulates casein secretion by metabolic products different from prostaglandins.
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology; D002364:Caseins / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D007774:Lactation; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000378:metabolism*; D008892:Milk / Q000187:drug effects / Q000378:metabolism*; D011247:Pregnancy; D011388:Prolactin / Q000494:pharmacology; D011817:Rabbits
D001095:Arachidonic Acids; D002364:Caseins; D016718:Arachidonic Acid; D011388:Prolactin; D001241:Aspirin
Effet de l'acide arachidonique sur la sécrétion des caséines du lait in vitro.