DNA repair in cells from patients with actinic keratosis.
UV-induced DNA repair was studied in peripheral blood lymphocytes from patients with multiple actinic keratoses (AK) requiring surgical therapy and from age-matched normal control individuals. The DNA repair activity in lymphocytes from AK patients at 4 h after UV-irradiation was 50% of that in control lymphocytes, but at 21 h the extent of DNA repair synthesis was similar to that in control cells.
D004260:DNA Repair; D006801:Humans; D007642:Keratosis / Q000097:blood* / Q000209:etiology / Q000503:physiopathology; D007700:Kinetics; D008214:Lymphocytes / Q000378:metabolism*; D013942:Thymine Nucleotides / Q000378:metabolism; D014466:Ultraviolet Rays / Q000009:adverse effects*
D013942:Thymine Nucleotides