Spontaneous AKR lymphomas differ in their degree of malignancy and sensitivity to the polysaccharide levan.
Spontaneous AKR lymphomas differ in their biological behavior as judged by formation of local tumors at the site of inoculation, latency in the appearance of both local and distant tumors and mean survival time of the mice. Spontaneous AKR lymphomas differ markedly in their sensitivity to levan (polyfructose). An inverse correlation was observed between the degree of malignancy and sensitivity to levan.
D000818:Animals; D005630:Fructans / Q000627:therapeutic use*; D008223:Lymphoma / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D009368:Neoplasm Transplantation; D011134:Polysaccharides / Q000627:therapeutic use*
D005630:Fructans; D011134:Polysaccharides