[Turnover of gamma-aminobutyric acid (GABA) in neurons and glial cells of the chick embryo in culture].
The turnover rates of gamma-aminobutyric acid (GABA) in cultured neurons and glial cells of Chicken embryo were measured by using a gas chromatography/mass spectrometric method. The method followed involved monitoring of the time course of changes in the enrichment of deuterium in GABA following incubation with pentadeuterated glutamate in the medium. The GABA turnover rate in neurons was found to be nearly eight fold greater than in glial cells.
D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D008401:Gas Chromatography-Mass Spectrometry; D007700:Kinetics; D013058:Mass Spectrometry; D009457:Neuroglia / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid
Renouvellement de l'acide gamma-aminobutyrique (GABA) dans les neurones et les cellules gliales d'embryon de poulet en culture.