[Blastomogenic activity of sulfotrinaphthylene furan].
The biological (including carcinogenic) effect of an anthraquinone dye sulfoderivative--sulfotrinaphthylenfuran--was studied. The agent displayed low toxicity and cumulation in different species of experimental animals and germ cultures. However, a long-term intoxication by the agent led to tumor formation in the lungs of albino mice, following the pattern of focal reticulosis. The blastogenic effect of sulfotrinaphthylenfuran is suggested.
D000818:Animals; D000880:Anthraquinones / Q000494:pharmacology* / Q000633:toxicity; D004396:Coloring Agents / Q000494:pharmacology* / Q000633:toxicity; D005663:Furans / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D008175:Lung Neoplasms / Q000139:chemically induced; D008206:Lymphatic Diseases / Q000139:chemically induced; D051379:Mice; D009281:Naphthalenes / Q000494:pharmacology* / Q000633:toxicity; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D051381:Rats; D012511:Sarcoma 37 / Q000139:chemically induced; D013997:Time Factors
D000880:Anthraquinones; D004396:Coloring Agents; D005663:Furans; D009281:Naphthalenes
O blastomogennoĭ aktivnosti sul'fotrinaftilenfurana.