Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene A4, a stable analogue of leukotriene A4.
D000818:Animals; D001091:Arachidonate Lipoxygenases; D001095:Arachidonic Acids / Q000494:pharmacology*; D002460:Cell Line; D016861:Cyclooxygenase Inhibitors; D007700:Kinetics; D017572:Leukotriene A4 / Q000031:analogs & derivatives*; D016859:Lipoxygenase Inhibitors; D012515:Mast-Cell Sarcoma / Q000201:enzymology; D051379:Mice; D009374:Neoplasms, Experimental / Q000201:enzymology; D013329:Structure-Activity Relationship
D001095:Arachidonic Acids; D016861:Cyclooxygenase Inhibitors; D017572:Leukotriene A4; D016859:Lipoxygenase Inhibitors; C035609:5,6-methanoleukotriene A4; D001091:Arachidonate Lipoxygenases