Tricyclic antidepressants for children with cancer.
Eight depressed children with cancer had a rapid clinical response to low doses of imipramine or amitriptyline. Because of the many variables affecting cancer patients, the mechanism by which tricyclic antidepressant treatment produced this response is unclear.
D000293:Adolescent; D000639:Amitriptyline / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D008297:Male; D009369:Neoplasms / Q000150:complications* / Q000523:psychology
D000639:Amitriptyline; D007099:Imipramine