title: Effect of heat treatment of human breast milk on its anti-endotoxin antibody activities.
abstract: Pooled human breast milk is frequently heat treated before administration to neonates in order to reduce the risk of spreading infection. However, heating such milk by two different routine hospital procedures totally inactivated anti-endotoxin antibodies present, thus greatly reducing the benefit of administering breast milk. Temperature-time parameters of the heat treatment of human breast milk were studied to determine the limits of anti-endotoxin IgG and IgA activities.
mesh_terms: D000992:Antitoxins / Q000032:analysis*; D004731:Endotoxins / Q000032:analysis; D005519:Food Preservation; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology*; D008895:Milk, Human / Q000276:immunology*; D013696:Temperature; D013997:Time Factors
chemical_list: D000992:Antitoxins; D004731:Endotoxins; D007070:Immunoglobulin A; D007074:Immunoglobulin G