title: Nanoliter tracking of the tears.
abstract: Microliter sampling opened the way in the 1970's for at least limited quantitative studies of the tear fluid. Now, nanoliter sampling offers a much less imposing technique for viewing even more subtle changes within the eye's most immediate environment. Examples, based on nanoliter sampling, are given of certain transient effects that even a soft lens can induce during the earliest periods of wear.
mesh_terms: D003263:Contact Lenses, Hydrophilic; D006801:Humans; D008832:Microchemistry / Q000295:instrumentation / Q000379:methods; D009994:Osmolar Concentration; D013666:Tears / Q000032:analysis*; D013997:Time Factors