Testosterone secretion of rat and mouse Leydig cells cultured at plates precoated with collagen taken from male and female rats.
Testosterone secretion by Leydig cells in vitro was significantly higher on male collagen coated, than on female collagen coated plates. The castration of male rat-donors of collagen demonstrated that 2 months of androgen deprivation eliminated the effect.
D000818:Animals; D002369:Castration; D002478:Cells, Cultured; D003094:Collagen / Q000502:physiology*; D005260:Female; D007985:Leydig Cells / Q000378:metabolism*; D008297:Male; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D013739:Testosterone / Q000378:metabolism*
D013739:Testosterone; D003094:Collagen