Relationship between cell size and weight of the human liver. An automated morphometric study.
Using a machine-vision system for the analysis of multicolor multicellular images, an algorithm, consisting of cellular logic operators, was developed for estimating the average cross-sectional area of cells in the liver. A total of 28 three-color histologic images from 22 variable-weight autopsied livers were digitized and processed. The data collected showed a positive correlation, albeit weak, between the weight of the liver and the cell size. This correlation was not visually evident, which demonstrates the utility of machine vision in histopathology.
D000328:Adult; D000368:Aged; D003201:Computers; D005260:Female; D006801:Humans; D008099:Liver / Q000033:anatomy & histology* / Q000166:cytology; D008297:Male; D008853:Microscopy / Q000379:methods; D008875:Middle Aged; D055095:Optics and Photonics; D009929:Organ Size