Renal growth and scarring in kidneys with reflux and a concentrating defect.
A study was done to determine if kidneys with reflux and an associated renal concentrating defect grew less well and had more scars than kidneys with reflux but no renal concentrating defect. To test our hypothesis we measured renal growth and assessed radiographs for renal scars in 11 children with and 20 children without a renal concentrating defect. Kidneys with reflux and a renal concentrating defect grew less well and had more scars than those kidneys with reflux but no renal concentrating defect. A persistent renal concentrating defect may be a predictor of kidneys more likely to have impaired growth and renal scars.
D002648:Child; D002921:Cicatrix / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000254:growth & development* / Q000473:pathology; D007671:Kidney Concentrating Ability; D014718:Vesico-Ureteral Reflux / Q000473:pathology / Q000503:physiopathology*