title: A comparison of the surface activities of rat plasma apolipoproteins C-II, C-III-0, C-III-3.
abstract: Rat apolipoproteins C-II, C-III-0 and C-III-3 give similar surface pressure (pi)-molecular area isotherms when spread at the air/water interface. When allowed to adsorb to the clean air/water interface, the intrinsic surface activity of apolipoprotein C-II is somewhat higher than that of apolipoprotein C-III. All three apolipoprotein C molecules can penetrate an egg phosphatidylcholine monolayer spread at the air/water interface causing an increase (delta pi) in surface pressure. Increasing the initial surface pressure (pi i) of the lipid monolayer decreases delta pi, and delta pi = 0 when pi i greater than or equal to 32 +/- 2 mN . m-1 for all three apolipoprotein C proteins. This implies that apolipoproteins C-II, C-III-0 and C-III-3 would adsorb and desorb similarly from the surfaces of lipoprotein particles during metabolism.
mesh_terms: D000327:Adsorption; D000818:Animals; D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001053:Apolipoproteins / Q000097:blood*; D001056:Apolipoproteins C; D055598:Chemical Phenomena; D002621:Chemistry; D051381:Rats; D013500:Surface Tension
chemical_list: D053304:Apolipoprotein C-II; D053305:Apolipoprotein C-III; D001053:Apolipoproteins; D001056:Apolipoproteins C