title: Maturation in the ferret ileal epithelium and the effect of cortisone acetate.
abstract: Normal maturation ('closure') in the ferret ileal epithelium occurs, between 35 and 39 days after birth, by a process of cellular replacement. The administration of cortisone acetate at doses up to 1.2 mg/g body weight for 5 days failed to promote any morphological changes in the ileal epithelium in this non-rodent species, and the results suggest that the maturing effect of cortisone acetate in the rat might be peculiar to the rodents.
mesh_terms: D000375:Aging; D000818:Animals; D002335:Carnivora / Q000033:anatomy & histology*; D003348:Cortisone / Q000031:analogs & derivatives* / Q000494:pharmacology; D004848:Epithelium / Q000648:ultrastructure; D005289:Ferrets / Q000033:anatomy & histology*; D007082:Ileum / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D014617:Vacuoles / Q000648:ultrastructure
chemical_list: D003348:Cortisone