[Clinico-genetic characteristics of psychoses with a clinical picture of involutional melancholia].
The author examined 34 probands with late endogenous paroxysmal psychoses and a characteristic picture of involutional melancholy at a certain stage of the disease. The accumulation of schizophrenia and affective psychoses among the next-kin relatives of these patients was significantly lower than in the families of patients with paroxysmal schizophrenia and manic-depressive psychosis of an early onset, but at the same time it was considerably higher than the risk of morbidity in the general population. No accumulation of psychoses of any other nosological nature (including those of a mentality deteriorating type) was observed. A possible genetic relationship between the disorder in the group of patients under study and the presence of "involutional" symptomatology with endogenous psychoses in the clinical picture of "the disease is discussed.
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000235:genetics; D000367:Age Factors; D000368:Aged; D001714:Bipolar Disorder / Q000235:genetics; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012306:Risk; D012559:Schizophrenia / Q000235:genetics; D013577:Syndrome
Kliniko-geneticheskaia kharakteristika psikhozov s kartinoĭ involiutsionnoĭ melankholii.