title: Efficacy of fenbendazole against tapeworms in calves.
abstract: Forty-five commercial-grade Angus calves naturally infected with tapeworms (Moniezia sp) were used in 2 controlled experiments to evaluate the cestocidal efficacy of 3 dosage levels of fenbendazole, methyl-5-(phenylthio) -2-benzimidazolecarbamate. In the 1st trial, 15 calves were divided into 3 groups of 5 each. One group served as nonmedicated controls. Other groups were drenched with fenbendazole at dosage rates of 10 and 15 mg/kg of body weight. Thirty calves used in the 2nd experiment were divided into 3 equal groups. One group served as nonmedicated controls and the other 2 groups were drenched at dosage rates of 7.5 and 10 mg/kg. Calves were necropsied 13 days after treatment. Doses of 10 and 15 mg/kg were 100% efficacious in reducing the number of tapeworm scolices, and a dose of 7.5 mg/kg was 91.7% effective. Signs of toxicosis were not observed in medicated cattle from time of treatment to necropsy.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary*; D005273:Fenbendazole / Q000627:therapeutic use*
chemical_list: D001562:Benzimidazoles; D005273:Fenbendazole