[Detection of secretory immunoglobulin A in cervical secretion and in cervicovaginal irrigation fluids].
Secretory immunoglobulin A (S-IgA) is an essential part of local immune system of female genital tract. Accordingly the estimation of S-IgA in female genital secretions is important for judgement of immunologic problems in female genital tract. The estimation of S-IgA was carried out by means of an antiserum against human secretory component (anti SC) and S-IgA standard. It was used the single radial immunodiffusion according to Mancini and co-workers. Our results refer to changes in the quantity of S-IgA locally produced in the mucous membranes of female genital tract correlated to the menstrual cycle. The essential results are a decrease of S-IgA in midcycle in cervical mucus and vaginal fluids as well as of fertile and sterile patients.
D000328:Adult; D002584:Cervix Uteri / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D007247:Infertility, Female / Q000276:immunology; D008598:Menstruation; D014621:Vagina / Q000276:immunology*
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory
Nachweis der sekretorischen Immunglobulin A im Zervixsekret und in Zervikovaginalspülflüssigkeiten.