title: Band-3 protein-mediated anion conductance of the red cell membrane. Slippage vs ionic diffusion.
abstract: The band 3 protein-mediated, valinomycin-induced KCl efflux continues to increase with increasing [KCl] when the Cl-/Cl- equilibrium exchange becomes saturated. This suggests the existence of a band 3-mediated component of Cl- flux that contributes to the electrical conductance without being related to slippage; i.e., equilibration of the unloaded transport protein between the two membrane surfaces.
mesh_terms: D017878:4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid / Q000031:analogs & derivatives*; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D001457:Anion Exchange Protein 1, Erythrocyte; D000838:Anions; D001692:Biological Transport / Q000187:drug effects; D001798:Blood Proteins / Q000502:physiology*; D002712:Chlorides / Q000097:blood*; D004058:Diffusion; D004553:Electric Conductivity; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology*; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans; D011189:Potassium Chloride / Q000097:blood; D014634:Valinomycin / Q000494:pharmacology
chemical_list: D001457:Anion Exchange Protein 1, Erythrocyte; D000838:Anions; D001798:Blood Proteins; D002712:Chlorides; D014634:Valinomycin; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; C018564:dihydro-DIDS; D011189:Potassium Chloride; D017878:4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid