title: [Amenorrhea in drug dependence].
abstract: Irregular menstrual cycles are fairly common in drug-addicted patients. The purpose of this research is to stablish the connection between the administration of a narcotic and the onset of amenorrhoea. After a review of the literature and aetiopathogenetic hypotheses regarding ovulatory block, 39 heroin- or morphine-addicted patients personally observed during pregnancy are studied. Even relatively low doses of narcotics can impair normal ovarian function and ovulation so there is a risk that menstrual irregularities can arise even when doses are reduced.
mesh_terms: D000568:Amenorrhea / Q000139:chemically induced*; D005260:Female; D006556:Heroin Dependence / Q000150:complications; D006801:Humans; D009021:Morphine Dependence / Q000150:complications; D010060:Ovulation / Q000187:drug effects; D019966:Substance-Related Disorders / Q000150:complications*
vernacular_title: L'amenorrea nella farmacodipendenza.