Adenosquamous carcinoma of the thyroid after radiotherapy for Hodgkin's disease. A case report and review.
This is a case report of a patient who had received radiation therapy for Hodgkin's disease and 48 years later developed adenosquamous carcinoma of the thyroid gland. Radiation associated thyroid carcinoma is usually of differentiated variety and carried no different prognosis than one not related to radiation. Coexisting adenocarcinoma and squamous cell carcinoma is a very rare event, but makes the prognosis of patients with thyroid carcinoma much poorer. As a result, this kind of patient requires early recognition and aggressive therapy.
D000230:Adenocarcinoma / Q000209:etiology*; D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects*; D013964:Thyroid Neoplasms / Q000209:etiology*