The murine ependymoblastoma: growth pattern and survival in C57Bl/6J mice.
The murine ependymoblastoma is a transplantable tumor of cerebral origin. The growth pattern and survival times of the murine ependymoblastoma implanted peripherally and intracranially in non nude C57Bl/6J mice have been found to be predictable and consistent when examined by means of Tumor Cell Dose Assessment (end point solution), Tumor Growth and Survival Assessment. The results suggest that a greater tumor cell dose is required to generate peripheral tumor take than brain tumor take. This difference may result from a greater immunologic response to tumor implanted peripherally than into the immunologically privileged brain.
D000818:Animals; D001932:Brain Neoplasms / Q000139:chemically induced / Q000401:mortality / Q000503:physiopathology*; D004806:Ependymoma / Q000139:chemically induced / Q000401:mortality / Q000503:physiopathology*; D008748:Methylcholanthrene; D051379:Mice; D008810:Mice, Inbred C57BL / Q000502:physiology*; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000401:mortality / Q000503:physiopathology
D008748:Methylcholanthrene