Isolation and sequence of a non-opioid peptide derived from proenkephalin.
A non-opioid peptide derived from adrenal proenkephalin has been isolated and sequenced. The sequence of this peptide is Ser-Pro-His-Leu-Glu-Asp-Glu-Thr-Lys-Glu-Leu-Gln (Proenkephalin 168-180). This sequence represents the portion of Peptide I that is cleaved to yield Peptide E. This peptide is processed in a similar manner to the opioid peptides and is present at approximately the same level as Peptide E.
D000311:Adrenal Glands / Q000032:analysis; D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004745:Enkephalins / Q000032:analysis*; D010446:Peptide Fragments / Q000302:isolation & purification*; D011498:Protein Precursors / Q000032:analysis*
D004745:Enkephalins; D010446:Peptide Fragments; D011498:Protein Precursors; C029992:proenkephalin