The structure of the bladder neck in male bladder neck obstruction.
A light microscope and neurohistochemical study is presented of full thickness biopsies from the bladder neck of 10 middle-aged males with urodynamically proven bladder neck obstruction. Apart from varying degrees of collagen deposition in seven cases, no abnormality was present in the detrusor and pre-prostatic components of the bladder neck muscles or in the distribution of cholinergic nerve fibres. The normal noradrenergic innervation to the pre-prostatic sphincter was absent in all specimens; this may be age-related.
D000328:Adult; D000368:Aged; D002799:Cholinergic Fibers / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D001743:Urinary Bladder / Q000294:innervation / Q000473:pathology*; D001748:Urinary Bladder Neck Obstruction / Q000473:pathology*