Thrombosis associated with a porcine bioprosthesis and ascending aortic graft in a patient with the Marfan syndrome.
A fatal thrombosis originating at the junction of an aortic bioprosthetic heart valve and a Dacron aortic graft was observed in a patient with the Marfan syndrome, who had had replacement of the ascending aorta with a valved conduit 29 months previously. This unique complication raises the question of whether patients with such prostheses should be on a program of full anticoagulation.
D000328:Adult; D001011:Aorta / Q000601:surgery*; D001021:Aortic Valve; D001705:Bioprosthesis / Q000009:adverse effects*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D003327:Coronary Disease / Q000209:etiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000150:complications*