title: Mathematical model of the human ankle joint.
abstract: It has been suspected that the mechanical environment in which a particular joint functions has an effect on the initiation or progression of degenerative joint disease. The objective of this study is to define the mechanical environment of the ankle joint, specifically, the contact areas and pressure distributions, through the development and analysis of a simplified mathematical model. Since the state of pressure across articular surfaces during function is influenced by joint incongruity, cartilage thickness profile and the geometry of the opposing surfaces, these factors have been incorporated into the model formulation. Mathematical analysis of the model has resulted in pressure distributions in both the anterior-posterior and medial-lateral directions and contact area growth plots which correlate well with observed ankle contact patterns obtained from in vitro investigations. The significance of joint incongruity to these pressure distributions and to the relative immunity of the ankle joint to primary osteoarthritis is discussed.
mesh_terms: D000843:Ankle Joint / Q000033:anatomy & histology* / Q000503:physiopathology; D001696:Biomechanical Phenomena; D002356:Cartilage / Q000033:anatomy & histology; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D010003:Osteoarthritis / Q000503:physiopathology