Differences in vitamin E levels in tissues of the spontaneously hypertensive and Wistar-Kyoto rats.
Tissue vitamin E levels were significantly lower in spontaneously hypertensive rats (SHR) than in the normotensive, genetically related Wistar/Kyoto (W/K). This difference was also observed when animals were given identical oral doses of vitamin E. The possible relationship of lower vitamin E tissue levels to lower immune responses in the SHR is discussed.
D000818:Animals; D006973:Hypertension / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism; D014018:Tissue Distribution; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
D014810:Vitamin E; D024502:alpha-Tocopherol; D024505:Tocopherols