Isolation and amino acid compositions of geographutoxin I and II from the marine snail Conus geographus.
The peptide toxins having inhibitory effects on the contractile response of the mouse diaphragm to direct stimulation, geographutoxin I and II, have been isolated from Conus geographus, and their amino acid compositions have been determined.
D000596:Amino Acids / Q000032:analysis*; D000818:Animals; D003964:Diaphragm / Q000502:physiology; D004558:Electric Stimulation; D004586:Electrophoresis; D008387:Marine Toxins / Q000302:isolation & purification; D051379:Mice; D008978:Mollusk Venoms / Q000302:isolation & purification* / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009498:Neurotoxins; D010456:Peptides, Cyclic; D012908:Snails / Q000032:analysis*
D000596:Amino Acids; D008387:Marine Toxins; D008978:Mollusk Venoms; D009498:Neurotoxins; D010456:Peptides, Cyclic; C038093:geographutoxin I; C038094:geographutoxin II