Impairment of antipyrine metabolism in urinary tract cancer.
The metabolism of antipyrine was studied in 13 patients with cancer and bladder papillomas and in 11 control subjects, matched for interfering factors like smoking, diet, age and sex. The mean antipyrine half-life was significantly longer in patients with urinary tract cancer (14.7 +/- 1.32 h SE) than in control subjects (11 +/- 0.55 h SE) (P less than 0.025); other clinical parameters did not vary.
D000328:Adult; D000983:Antipyrine / Q000008:administration & dosage / Q000097:blood*; D006207:Half-Life; D006801:Humans; D008297:Male; D014571:Urologic Neoplasms / Q000097:blood*
D000983:Antipyrine