Regional cerebral blood flow in the acute stage of experimentally induced subarachnoid hemorrhage.
Subarachnoid hemorrhage (SAH) was induced in 13 adult mongrel cats by a slow injection of fresh autogenous blood into the cisterna magna. Serial determinations of regional cerebral blood flow (rCBF) in the cortex and deep-seated areas (internal capsule, thalamus, and caudate nucleus) were made during the following 2 hours, while intracranial pressure (ICP) was maintained at normal values. A decrease in rCBF was observed in all the areas examined. This reduction followed a characteristic triphasic pattern with an initial steep decline immediately after the SAH. The clinical implications of these findings are discussed.
D000818:Animals; D001794:Blood Pressure; D001921:Brain / Q000098:blood supply*; D002415:Cats; D002421:Caudate Nucleus / Q000503:physiopathology; D002540:Cerebral Cortex / Q000503:physiopathology; D007427:Intracranial Pressure; D012039:Regional Blood Flow; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology*; D013788:Thalamus / Q000503:physiopathology