Identification of the major urinary metabolites of (+)-catechin and 3-O-methyl-(+)-catechin in man.
Following oral administration of (+)-catechin and 3-O-methyl-(+)-catechin to human volunteers the major urinary metabolites were shown to be the glucuronides of 3'-O-methyl-(+)-catechin respectively. Isolations from urine and from synthetic products have been carried out by semi-preparative high performance liquid chromatography; definitive elucidations of structures have been carried out by gas chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy.
D001578:Benzopyrans / Q000652:urine*; D001711:Biotransformation; D002392:Catechin / Q000031:analogs & derivatives / Q000652:urine*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation
D001578:Benzopyrans; C029339:meciadanol; D002392:Catechin