Heterochromatic regions on chromosomes 1, 9, 16, and Y in children with some disturbances occurring during embryo development.
Some reduction of C-segment lengths and their variability on chromosomes 1, 9, 16, and Y was exhibited by children who had had some disturbances at early stages of morphogenesis. The data obtained might suggest a certain activity of the heterochromatic regions during embryo development. Based on this data one may also suppose that reduction of the amount of heterochromatin might affect the normal morphogenetic processes.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002871:Chromosome Banding; D002900:Chromosomes, Human, 1-3; D002902:Chromosomes, Human, 16-18; D002906:Chromosomes, Human, 6-12 and X; D000013:Congenital Abnormalities / Q000235:genetics*; D004622:Embryo, Mammalian / Q000502:physiology*; D005260:Female; D014644:Genetic Variation; D006570:Heterochromatin / Q000648:ultrastructure*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009024:Morphogenesis; D011110:Polymorphism, Genetic; D011247:Pregnancy; D012730:Sex Chromosomes; D014998:Y Chromosome
D006570:Heterochromatin