title: Output of endogenous monoamine oxidase inhibitor in rats: effect of ethanol, tryptamine and tryptophan.
abstract: Contrary to prediction, loading rats with tryptamine, tryptophan or methanol failed to produce any rise in endogenous monoamine oxidase inhibitor output, whilst ethanol administration resulted in a significantly decreased excretion. These findings, which provide no support for the hypothesis that the inhibitor is a beta-carboline, may shed some light on the tranquilizing effect of ethanol in man.
mesh_terms: D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D000432:Methanol / Q000494:pharmacology; D008996:Monoamine Oxidase Inhibitors / Q000096:biosynthesis*; D051381:Rats / Q000378:metabolism*; D011919:Rats, Inbred Strains; D014363:Tryptamines / Q000494:pharmacology*; D014364:Tryptophan / Q000494:pharmacology*
chemical_list: D008996:Monoamine Oxidase Inhibitors; D014363:Tryptamines; D000431:Ethanol; D014364:Tryptophan; D000432:Methanol