[Microspectrophotometric study of the DNA content of the nucleus of cells from premalignant polyps and cancer of the rectum].
38 adenomatous polyps, 42 villous polyps with varying degree of proliferation and epithelial dysplasia, 34 polyps with preinvasive cancer components and 44 polyps containing invasive cancer elements were examined microspectrophotometrically. The analysis established an increased level of epithelial cells with ploidy varying 3c-5c to be a characteristic feature of the initial stages of malignant transformation of rectal polyps. The invasive cancer had similar peculiarities.
D000328:Adult; D002467:Cell Nucleus / Q000032:analysis*; D002471:Cell Transformation, Neoplastic / Q000032:analysis*; D004247:DNA / Q000032:analysis*; D004848:Epithelium / Q000032:analysis; D006801:Humans; D007417:Intestinal Polyps / Q000032:analysis*; D008875:Middle Aged; D011003:Ploidies; D012004:Rectal Neoplasms / Q000032:analysis*; D013053:Spectrophotometry / Q000379:methods
D004247:DNA
Mikrospektrofotometricheskoe issledovanie soderzhaniia DNK v iadrakh kletok maligniziruiushchikhsia polipov i raka priamoĭ kishki.