Formation of N-nitrosomorpholine in isolated rat lungs during nitrogen dioxide ventilation.
An isolated rat lung preparation was ventilated with NO2 while being perfused with a medium containing morpholine. After 60 min of ventilation-perfusion, N-nitrosomorpholine was detected in both lung tissue and perfusate.
D000818:Animals; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009585:Nitrogen Dioxide / Q000494:pharmacology*; D009602:Nitrosamines / Q000378:metabolism*; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains
D009602:Nitrosamines; C002741:N-nitrosomorpholine; D009585:Nitrogen Dioxide