The dilemma of the creatine kinase cardiospecific iso-enzyme (CK-MB) in marathon runners.
Serum creatine kinase iso-enzyme (CK-MB) levels were measured in 51 marathon runners before and after a 50 km marathon event. Ninety-five per cent of the runners were found to have pathologically elevated values, i.e. CK-MB concentrations were elevated to the range normally considered indicative of myocardial necrosis. Results indicate that a rise in the CK-MB level is common after marathon running. We therefore believe that cardiac enzymes are an unreliable indicator of myocardial infarction in patients who experience chest pain following strenuous muscular exercise.
D000328:Adult; D000368:Aged; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007527:Isoenzymes; D008875:Middle Aged; D012420:Running; D013178:Sports Medicine
D007527:Isoenzymes; D003402:Creatine Kinase