title: The use of induced hypotension to control bleeding during posterior fusion for scoliosis.
abstract: The operative and anaesthesic technique for 44 patients undergoing posterior spinal fusion with Harrington rod instrumentation for idiopathic scoliosis is described. There were two groups of 21 and 23 patients, matched for diagnosis and status before operation. The management of both groups was similar but in one group anaesthesia with induced hypotension was employed, using a mixture of sodium nitroprusside and trimetaphan. The mean blood loss at operation and after operation in this group was significantly lower than in the other group, with a consequent reduction in the transfusion requirement. No adverse sequelae were observed. All patients showed a drop in haemoglobin concentration after operation, despite clinically adequate blood transfusion.
mesh_terms: D000293:Adolescent; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D007023:Hypotension, Controlled; D007431:Intraoperative Complications / Q000517:prevention & control*; D008297:Male; D009599:Nitroprusside / Q000008:administration & dosage; D012600:Scoliosis / Q000601:surgery*; D013123:Spinal Fusion; D014294:Trimethaphan / Q000008:administration & dosage
chemical_list: D006454:Hemoglobins; D009599:Nitroprusside; D014294:Trimethaphan