The zoapatle IV--toxicological and clinical studies.
The zoapatle aqueous crude extract has been used in Mexico for the last 5 centuries for the induction of labor, treatment of post-partum bleeding problems, and as a menses inducer. Today, it is sold in street markets, and its long documented history of use by humans could be taken as indirect evidence of a lack of toxicity. Rigorous pharmacological and clinical studies described here, fully confirm the empirical observations.
D000818:Animals; D001772:Blood Cell Count; D001774:Blood Chemical Analysis; D001835:Body Weight / Q000187:drug effects; D002584:Cervix Uteri / Q000187:drug effects; D004285:Dogs; D005260:Female; D006801:Humans; D008253:Macaca mulatta; D035924:Montanoa; D010082:Oxepins / Q000009:adverse effects*; D010936:Plant Extracts / Q000633:toxicity*; D010946:Plants, Medicinal; D011247:Pregnancy; D051381:Rats
D010082:Oxepins; D010936:Plant Extracts