title: Immunization of turkey breeder hens against fowl cholera by combined oral and wing-web administration of attenuated (CU) pasteurella multocida.
abstract: Turkey breeder candidates were exposed to attenuated Pasteurella multocida (Clemson University strain) via both mouth (one or three times) and wing-web stick (one or two times). Significant protection lasting to 25-30 weeks post-vaccination was conferred under such immunization programs. The best protection with the fewest adverse effects of vaccination was established when orally vaccinated turkeys were subsequently vaccinated via wing-web at 20 and 25 weeks of age. High doses of attenuated P. multocida via wing-web produced lameness (synovitis and osteomyelitis) and severe wing lesions in growing turkeys.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D005260:Female; D007267:Injections / Q000662:veterinary; D010325:Pasteurella / Q000276:immunology*; D010326:Pasteurella Infections / Q000276:immunology / Q000662:veterinary*; D011201:Poultry Diseases / Q000276:immunology*; D014422:Turkeys; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology; D014921:Wings, Animal
chemical_list: D001428:Bacterial Vaccines; D014613:Vaccines, Attenuated