title: [Androgens: a critical study of the biological diagnosis of the hirsute women. Screening for incomplete blockage of 21-hydroxylase].
abstract: In 19 patients with unexplained hirsutism without virilisation, a check-up includes delta 4- androstenedione (A), testosterone, DHEA-S. A appears like the best hyperandrogenemia parameter. Nevertheless 5 patients among this group have normal values of all these hormones. A mild congenital adrenal hyperplasia by 21 hydroxylase deficiency is revealed by abnormal response of 17 -OH-progesterone in the cosyntropin test. Our normal value of delta-OHP is, according to Gutai, method, 1.58 +/- 0.83 NG/DL/MN.
mesh_terms: D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood*; D006579:Heterozygote; D006628:Hirsutism / Q000097:blood* / Q000201:enzymology / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000172:deficiency*
chemical_list: D000728:Androgens; D006899:Mixed Function Oxygenases
vernacular_title: Androgènes, étude critique du diagnostic biologique chez la femme hirsute. Dépistage des blocages incomplets de la 21-hydroxylase.