title: Primary treatment of breast cancer in elderly women with Tamoxifen.
abstract: One hundred and sixty-one female patients, over the age of 70, with breast cancer were treated by Tamoxifen alone in a pilot phase II study. 61% showed objective regression of the disease and in 27% there was complete remission. The treatment was well tolerated and the survival rate compared favourably to that following conventional methods of treatment. An accurate assessment of the method awaits a randomized clinical trial.
mesh_terms: D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local; D013629:Tamoxifen / Q000627:therapeutic use*
chemical_list: D013629:Tamoxifen