[Alterations of carbohydrate-containing components in glycoproteins of blood serum and blood cells from hypothyroid rats].
Effect of simultaneous treatment with various doses of 6-methylthiouracil and thyroidectomy on content of carbohydrate-containing glycoproteins was studied in blood serum and plasmatic membranes of rat erythrocytes and leukocytes. Doses and schedule of the thyrostatics administration determined their effect on concentration of the glycoproteins studied. Correlation of various degree and significance was found between the alterations in content of individual carbohydrate-containing components, especially in membranes of erythrocytes and leukocytes. The data obtained enabled to elucidate the mechanisms of alterations in content of the glycoproteins studied in blood serum and plasmatic membranes of blood cells.
D000818:Animals; D002241:Carbohydrates / Q000032:analysis; D002462:Cell Membrane / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006023:Glycoproteins / Q000097:blood*; D007037:Hypothyroidism / Q000097:blood*; D007700:Kinetics; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D008565:Membrane Proteins / Q000097:blood*; D008779:Methylthiouracil; D051381:Rats; D013965:Thyroidectomy
D002241:Carbohydrates; D006023:Glycoproteins; D008565:Membrane Proteins; D008779:Methylthiouracil
Sravnitel'naia otsenka izmeneniĭ uglevodsoderzhashchikh komponentov glikoproteidov v syvorotke i formennykh élementakh krovi u gipotireoidnykh krys.