Small primary de novo adenocarcinoma of the colon with mesenteric lymphatic metastasis.
It is felt that the majority of colorectal carcinomas develop by malignant degeneration of previously benign adenomatous polyps. A small primary colon carcinoma, thought to have developed de novo directly from the colonic mucosa without the usual polyp-cancer sequence, is reported. This small nonulcerated lesion did not have the gross endoscopic appearance of a carcinoma and was associated with lymphatic metastasis. The need to include fiber-optic colonoscopy as part of the routine preoperative work-up and postoperative follow-up to rule out synchronous and metachronous lesions not detected by barium contrast x-ray studies is stressed.
D000230:Adenocarcinoma / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy; D005260:Female; D005336:Fiber Optic Technology; D005500:Follow-Up Studies; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007417:Intestinal Polyps / Q000473:pathology; D008207:Lymphatic Metastasis; D008643:Mesentery; D008875:Middle Aged; D055100:Optical Fibers; D010534:Peritoneal Neoplasms / Q000556:secondary*