title: [Hemosorption - a method of rapid elimination of cholesterol from the plasma and its effect on the regression of experimental atherosclerosis].
abstract: Hemosorption is a method of rapid control of hypercholesterolemia. A study of hemocompatibility of an alumosilicate sorbent which is relatively selective with respect to cholesterol demonstrated a possibility of its being used in hemosorption devices. Rabbits with spontaneous regression of two-month duration were given three hemosorption sessions. A drop in cholesterol and triglycerides was noted after each session. By the end of the experiment, the area of aortal atherosclerotic lesion was reduced twofold as compared to the controls (19% vs. 41%). Rapid regression of diffuse lipid deposits from the surface and marginal zones of the patches was observed. "New" secondary lipid deposits were absent. A possibility of using hemosorption in patients with pronounced hypercholesterolemia is discussed.
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000628:therapy*; D002784:Cholesterol / Q000097:blood; D006464:Hemoperfusion / Q000379:methods*; D006937:Hypercholesterolemia / Q000628:therapy*; D008297:Male; D011817:Rabbits; D012075:Remission, Spontaneous; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Gemosorbtsiia - metod bystrogo udaleniia kholesterina iz plazmy krovi i vliianie ee na regressiiu eksperimental'nogo ateroskleroza u krolikov.