K-cell activity in aplastic anaemia.
K-cell activity was measured by specific cytotoxicity and cytotoxic capacity in 29 patients with aplastic anaemia. 9 patients had a reduction of the specific cytotoxicity and 12 had a decreased cytotoxic capacity. The decreased cytotoxic capacity correlates with the severity of aplastic anaemia. Some of the possible causes of the reduction of this activity were investigated.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000741:Anemia, Aplastic / Q000276:immunology*; D000920:Antibody-Dependent Cell Cytotoxicity; D000936:Antigen-Antibody Complex / Q000276:immunology; D000961:Antilymphocyte Serum / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007694:Killer Cells, Natural / Q000276:immunology*; D008215:Lymphocytes, Null / Q000276:immunology; D008297:Male; D008875:Middle Aged
D000936:Antigen-Antibody Complex; D000961:Antilymphocyte Serum; D007074:Immunoglobulin G