Selenium levels in blood and plasma, and glutathione peroxidase activity in blood of breast cancer patients during adjuvant treatment with cyclophosphamide, methotrexate and 5-fluorouracil.
Glutathione peroxidase activity in whole blood and selenium levels in whole blood and plasma from breast cancer patients, were measured during combination chemotherapy with cyclophosphamide, methotrexate and 5-fluorouracil. No significant change in either glutathione peroxidase activity or selenium levels was observed. Comparison with matched controls showed no significant differences for either parameter.
D000328:Adult; D001943:Breast Neoplasms / Q000097:blood* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage*; D008875:Middle Aged; D010544:Peroxidases / Q000097:blood*; D012643:Selenium / Q000097:blood*
D003520:Cyclophosphamide; D010544:Peroxidases; D005979:Glutathione Peroxidase; D012643:Selenium; D005472:Fluorouracil; D008727:Methotrexate