Effects of hypo and hyperosmotic media on rabbit renal cortical slices.
Rabbit kidney cortex slices behave as osmometers when withstanding either hyperosmotic shocks or hypo-osmotic shocks of amplitude up to P1/P2 = 1.25. For hypo-osmotic shocks of amplitude larger or equal to P1/P2 = 1.5 a volume regulation process occurs. Na+ is the main osmotic effector implicated in volume control.
D000818:Animals; D007038:Hypotonic Solutions; D066298:In Vitro Techniques; D007672:Kidney Cortex / Q000502:physiology*; D009997:Osmotic Pressure; D011188:Potassium / Q000378:metabolism; D011817:Rabbits; D012462:Saline Solution, Hypertonic; D012964:Sodium / Q000378:metabolism; D012965:Sodium Chloride; D014882:Water-Electrolyte Balance
D007038:Hypotonic Solutions; D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D012964:Sodium; D011188:Potassium