[Iodized contrast media. I. effector action on serum enzymes].
In vitro studies were done to examine the effects of contrast media on blood enzymatic activities. The results observed are very significant: in the most simple cases they result in a competitive or mixed-type type inhibition of these enzymes. In systems which involve two substrates and two products a Bi-Bi ping-pong enzymatic mechanism is transformed in Bi-Bi random enzymatic mechanism.
D003287:Contrast Media / Q000009:adverse effects / Q000494:pharmacology*; D004791:Enzyme Inhibitors; D004798:Enzymes / Q000097:blood*; D006801:Humans; D066298:In Vitro Techniques; D007455:Iodine
D003287:Contrast Media; D004791:Enzyme Inhibitors; D004798:Enzymes; D007455:Iodine
Produits de contraste iodés. I. Action effectrice sur les enzymes sériques.