Comparison of methohexitone and etomidate for general anaesthesia in unpremedicated outpatients.
This study compares methohexitone (Brietal; Eli Lilly) and etomidate (Hypnomidate; Janssen) as hypnotic agents for the induction and maintenance of general anaesthesia in outpatients given fentanyl and nitrous oxide for analgesia but no premedication. While both agents provided suitable anaesthesia with a minimal incidence of side-effects, 66% of the patients who received methohexitone were noticeably drowsy 2 hours after the operation, whereas all but 3% of the patients who received etomidate were wide awake.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D005045:Etomidate; D005260:Female; D006801:Humans; D007093:Imidazoles; D008723:Methohexital; D008875:Middle Aged; D010045:Outpatients; D011292:Premedication
D007093:Imidazoles; D008723:Methohexital; D005045:Etomidate