[Levels of Krebs cycle metabolites in the blood and urine of patients with diabetes mellitus].
The blood oxaloacetate, alpha-ketoglutarate, malate and citrate concentrations and citrate excretion with the urine were studied in 86 patients with diabetes mellitus. An enhanced citrate content and lowered oxaloacetate, malate and alpha-ketoglutarate concentration were detected in the blood of patients with diabetes mellitus. Compensation of the disease and combined pathogenetic therapy are factors, promoting normalization of Krebs cycle metabolite content.
D000293:Adolescent; D000328:Adult; D002951:Citrates / Q000378:metabolism; D002952:Citric Acid Cycle; D003920:Diabetes Mellitus / Q000378:metabolism*; D005260:Female; D006801:Humans; D007656:Ketoglutaric Acids / Q000378:metabolism; D008293:Malates / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010071:Oxaloacetates / Q000378:metabolism
D002951:Citrates; D007656:Ketoglutaric Acids; D008293:Malates; D010071:Oxaloacetates
Soderzhanie metabolitov tsikla Krebsa v krovi i moche bol'nykh sakharnym diabetom.