title: Persisting selective block of unmyelinated fibers in cutaneous nerves of the cat by distilled water.
abstract: Experiments were done in vivo on the sural nerve of the cat's hindlimb. The nerve was desheathed for a length of 8 mm and superfused by Tyrode solution or distilled water. Electrical stimulation and recording was used to evaluate conduction block of nerve fibers. Irrigation with distilled water for periods of 3-5 min caused a persisting selective block of conduction in C-fibers while most of the A-fibers were unaffected. Recovery of the C-fibers never occurred during the time of observation (up to 130 min).
mesh_terms: D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D006614:Hindlimb / Q000294:innervation*; D009412:Nerve Fibers / Q000187:drug effects*; D009413:Nerve Fibers, Myelinated / Q000187:drug effects; D009431:Neural Conduction / Q000187:drug effects*; D012867:Skin / Q000294:innervation*; D013497:Sural Nerve / Q000187:drug effects; D014867:Water / Q000494:pharmacology*
chemical_list: D014867:Water