title: Quinidine photosensitivity.
abstract: Two patients with quinidine photosensitivity had an eczematous dermatitis in a photosensitivity distribution on the face, neck, hands, and forearms. Histologically, both patients showed a bandlike dermal lymphohistiocytic infiltrate with overlying vacuolar changes and necrosis in keratinocytes at the dermoepidermal junction. On phototesting, both patients showed marked sensitivity to UV-A radiation. Sensitivity to UV-B was difficult to assess.
mesh_terms: D000284:Administration, Oral; D000368:Aged; D001706:Biopsy; D004485:Eczema / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology; D011802:Quinidine / Q000009:adverse effects*; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D011802:Quinidine