[Characteristics of the effect of ether, sodium thiopental, fentanyl and naloxone on respiration].
It has been demonstrated in experiments on rabbits that anesthetic ether sodium thiopental, phentanyl and leucine-enkephalin have different inhibitory effects on the activity of inspiratory and expiratory neurons in the medulla oblongata. Bemegrid recovers the activity of the respiratory center inhibited by all the substances under study whereas naloxone eliminates apnea induced by phentanyl or leucine-encephalin alone. Besides, it has been ascertained that naloxone effectively abolishes the inhibition of the respiratory center caused by hyperventilation in rats.
D000818:Animals; D001049:Apnea / Q000139:chemically induced; D001534:Bemegride / Q000494:pharmacology; D004562:Electrocardiography; D004576:Electromyography; D004986:Ether / Q000494:pharmacology*; D005019:Ethyl Ethers / Q000494:pharmacology*; D005283:Fentanyl / Q000494:pharmacology*; D006985:Hyperventilation / Q000139:chemically induced; D009270:Naloxone / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects; D011817:Rabbits; D012119:Respiration / Q000187:drug effects*; D012125:Respiratory Center / Q000187:drug effects; D013874:Thiopental / Q000494:pharmacology*
D005019:Ethyl Ethers; D004986:Ether; D009270:Naloxone; D001534:Bemegride; D013874:Thiopental; D005283:Fentanyl
Osobennosti vliianiia éfira, tiopental-natriia, fentanila i naloksona na dykhanie.