Complications associated with immunotherapy of equine phycomycosis.
Five horses with pythiosis of the limbs were treated unsuccessfully by surgery or topical application of amphotericin B, or both. Follow-up immunotherapy resulted in 1 horse responding favorably. Three horses were cured of the fungal infection but developed osteitis or deep-seated laminitis, which necessitated their destruction. The remaining horse, which had severe anemia, died before the course of vaccination was completed.
D000818:Animals; D005260:Female; D005658:Fungi; D006734:Horse Diseases / Q000473:pathology / Q000628:therapy*; D006736:Horses; D007167:Immunotherapy / Q000662:veterinary; D008297:Male; D009181:Mycoses / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D011775:Pythium