HLA and keratoconus.
HLA-A and -B antigens were determined in 64 Caucasoid patients with keratoconus. A highly significant increase in the frequency of HLA-B5 was found among the patients. Thus keratoconus is the third eye disease after recurrent herpetic keratitis and Behcet's disease showing an association with HLA-B5.
D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D007640:Keratoconus / Q000235:genetics*; D010641:Phenotype
D006680:HLA Antigens