Discrimination of normal and dyskaryotic cells with a new high-resolution system (CIALIS).
Measurements on Feulgen-stained nuclei were performed with a new high-resolution system. Squamous intermediate cells and dyskaryotic cells in cervical smears were compared, based on nuclear features: DNA content, area and two features describing nuclear structure. For data evaluation, a histogram and a linear discriminant analysis were used. The discrimination of the two cell types based on the DNA content and nuclear area was possible to a high degree. A classification based only on the two chosen descriptors of chromatin patterns was not possible.
D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure; D003581:Cytodiagnosis / Q000379:methods*; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000032:analysis / Q000175:diagnosis* / Q000648:ultrastructure; D014626:Vaginal Smears
D002843:Chromatin; D004273:DNA, Neoplasm