[R plasmid distribution in S. typhi isolated on the territory of the left coast of the Ukraine in 1970-1982].
A total of 373 strains of S. typhi isolated in 1970-1982 were tested with respect to their sensitivity to 9 antibiotics active against gram-negative bacteria. It was shown that about 1/3 of the isolates were resistant to 1-3 antibiotics. Among the resistant isolates the number of strains resistant to 4-5 and more antibiotics amounted to 12.5 per cent. The plasmid nature of the antibiotic resistance in the isolated strains of S. typhi was shown. Transmissive R plasmids were detected in 13 per cent of the strains studied. Within the last 5 years there was an increase in the proportion of strains with transmissive R plasmids in patients with sporadic typhoid fever or especially in groups of patients with the disease.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D011815:R Factors; D012485:Salmonella typhi / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D014435:Typhoid Fever / Q000453:epidemiology / Q000382:microbiology; D014455:Ukraine
D000900:Anti-Bacterial Agents
Raporstraenenie R-plazmid u S. typhi, vydelennykh na territorii Levoberezhnoĭ Ukrainy v 1970-1982 gg.