[Effect of exogenous succinate on the contents of tricarboxylic acid cycle metabolites of the liver].
The paper deals with dynamics of tricarboxylic cycle metabolites in the liver after subcutaneous injection of succinate in a dose of 100 mg/kg to guinea pigs. Before the preparation administration the highest level was marked for succinate, malate and citrate. 3 h after the administration the succinate content increased by 57% and 6 h later it returns to the initial level. No essential changes were observed in the content of other tricarboxylic acid cycle metabolites.
D000818:Animals; D002951:Citrates / Q000378:metabolism; D002952:Citric Acid Cycle; D005260:Female; D006168:Guinea Pigs; D007656:Ketoglutaric Acids / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008293:Malates / Q000378:metabolism; D008297:Male; D013386:Succinates / Q000378:metabolism / Q000494:pharmacology*
D002951:Citrates; D007656:Ketoglutaric Acids; D008293:Malates; D013386:Succinates
Vliianie ékzogennogo suktsinata na soderzhanie metabolitov trikarbonovogo tsikla v pecheni.