Angioimmunoblastic lymphadenopathy with scleromyxedema-like lesions and serum monoclonal protein.
A patient was followed up for 5 yr for an illness diagnosed histologically as angioimmunoblastic lymphadenopathy. His serum contained a monoclonal protein of the IgM type, and biopsies from papular skin lesions revealed scleromyxedema-like features. The unusual association of this kind of cutaneous lesion with angioimmunoblastic lymphadenopathy and a monoclonal IgM is discussed.
D001856:Bone Marrow Examination; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications* / Q000276:immunology; D007075:Immunoglobulin M / Q000032:analysis; D008223:Lymphoma / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009194:Myeloma Proteins / Q000032:analysis; D011241:Prednisone / Q000627:therapeutic use; D012592:Scleredema Adultorum / Q000150:complications*; D014750:Vincristine / Q000627:therapeutic use
D007075:Immunoglobulin M; D009194:Myeloma Proteins; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone