[Energy balance of the myocardium and its correction using antiarrhythmics].
Changes in energetic balance (chi) during the transition of myocardium from norm to hypoxia and under antiarrhythmics effect were analysed on a mathematical model of the heart ventricle band. (chi-useful work/consumed energy ratio. Orciprenalin was shown to increase chi in the state close to the norm; quinidine, bretilium, procainamide, propranalol increase chi only under hypoxia; varapamile, as well as lidocain when it improves conduction ought to be effective for each initial (before therapy) state of the myocardium.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects*; D006321:Heart / Q000187:drug effects; D008433:Mathematics; D008954:Models, Biological; D009206:Myocardium / Q000378:metabolism*; D016276:Ventricular Function
D000889:Anti-Arrhythmia Agents
Energeticheskiĭ balans miokarda i ego korrektsiia antiaritmikami.