5-hydroxytryptophan elevates serum melatonin.
Daytime administration of 5-hydroxytryptophan to sheep elevated serum melatonin more than sevenfold within 2 hours. This suggests that administration of 5-hydroxytryptophan could be used as the basis of a clinical test of pineal function and that melatonin might mediate some clinical effects of 5-hydroxytryptophan.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood*; D010870:Pineal Gland / Q000502:physiology; D051381:Rats; D012701:Serotonin / Q000494:pharmacology*; D012756:Sheep; D014364:Tryptophan / Q000494:pharmacology
D012701:Serotonin; D014364:Tryptophan; D008550:Melatonin