New multi-cannula pedestal device for micro-injection of drugs into brain tissue or cerebral ventricle.
A new multiple-cannula-pedestal system for micro-injection of drugs directly into either brain tissue or cerebral ventricle is described. Its features include ease of construction from commonly available materials, no specialized machining required, durability and economy. A special aspect of the cannula system is a protective cap containing a bolt which threads onto a nut fixed within the pedestal base. Since the cap cannot be dislodged, potential damage to indwelling stylets and exposed guide tubes is prevented. Moreover, an aseptic preparation is therefore provided so that test compounds can be infused repeatedly over a prolonged period. Finally, the protective caps are interchangeable and the pedestal base itself can be re-cycled for usage in different animals.
D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D002552:Cerebral Ventricles / Q000033:anatomy & histology; D007276:Injections, Intraventricular / Q000295:instrumentation*; D008845:Microinjections / Q000295:instrumentation