Suxamethonium apnoea associated with pregnancy and liver dysfunction in a treated cretin.
A patient, with a history of cretinism, who developed suxamethonium apnoea as a consequence of a reduction in plasma cholinesterase activity secondary to the concurrence of pregnancy and liver dysfunction associated with pre-eclampsia is reported. The patient had a normal phenotype for plasma cholinesterase.
D000328:Adult; D000773:Anesthesia, Obstetrical / Q000009:adverse effects*; D001049:Apnea / Q000139:chemically induced*; D002585:Cesarean Section; D002802:Cholinesterases / Q000097:blood; D003409:Congenital Hypothyroidism / Q000150:complications*; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology; D011183:Postoperative Complications; D011225:Pre-Eclampsia / Q000150:complications* / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications; D013390:Succinylcholine / Q000009:adverse effects*
D002802:Cholinesterases; D013390:Succinylcholine