Correlation of leukocyte accumulation with chemotactic activity in the exudate of an allergic air-pouch inflammation.
Chemotactic activity at the site of an allergic air-pouch inflammation induced with azobenzene-arsonate-conjugated acetyl bovine serum albumin as an antigen was studied and a close correlation of the chemotactic activity with the intensity of leukocyte migration was demonstrated. In the period of vigorous leukocyte immigration into the fluid in the allergic air-pouch, chemotactic activity of the exudate was maintained at a high level, while no significant activity was detected after the number of leukocytes in the pouch fluid reached maximum.
D000818:Animals; D002634:Chemotaxis, Leukocyte; D005122:Exudates and Transudates / Q000166:cytology / Q000276:immunology; D007249:Inflammation / Q000276:immunology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012882:Skin Tests; D013997:Time Factors; D010132:p-Azobenzenearsonate / Q000276:immunology
D010132:p-Azobenzenearsonate