[Effect of hyperbaric oxygenation on the microsomal enzymes of the liver monooxygenase system in the rat].
Hyperbaric oxygenation of rats made at a pressure of 303.9 kPa (3 at. abs.) and 3-hour exposure induces in liver microsomes an increase (for 12 h) followed by a drop of NADP X H-ferricytochrome-c-reductase activity, reversible fall of cytochrome P-450 content, and inhibition of the rates of amidopyrine N-demethylation and aniline p-hydroxylation. Activity of NADP X H-nitrotetrasolium-, NAD X H-ferricyanide-, NAD X H-cytochrome-c-reductase and the content of cytochrome b5 remains essentially unchanged.
D000818:Animals; D004721:Endoplasmic Reticulum / Q000201:enzymology; D006900:Hydroxylation; D006931:Hyperbaric Oxygenation; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D009243:NAD; D009249:NADP; D010105:Oxygenases
Vliianie giperbaricheskoĭ oksigenatsii na mikrosomal'nye fermenty monooksigenaznoĭ sistemy pecheni krys.