[Results of a cytogenetic analysis of the peripheral blood lymphocytes of patients at different times after radiation therapy (up to 9 years)].
A study was made of the changes in the chromosome apparatus of peripheral blood leukocytes after radiotherapy of patients with uterine cervix cancer (a cumulative dose 70-90 Gy). Cells with the chromosome apparatus lesions and total amount of chromosome aberrations were intensively eliminated during the first 3-5 years following irradiation. Later (up to 7-9 years) their level stabilized to be 5-6 times higher than the control.
D000328:Adult; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects* / Q000648:ultrastructure; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000235:genetics / Q000532:radiotherapy
Rezul'taty tsitogeneticheskogo analiza limfotsitov perifericheskioĭ krovi patsientov v razlichnye sroki posle luchevoĭ terapii (do 9 let).