Effect of a 2 week course of oral salbutamol on adrenomedullary function in normal subjects.
1 The adrenal medullary response to intravenous histamine infusions (0.1 and 0.4 micrograms kg-1 min-1 histamine base) was studied in six normal subjects. 2 After a 2 week course of oral salbutamol (8 mg slow release twice daily) plasma adrenaline levels, thought to reflect adrenomedullary function, were unchanged both at rest and in response to histamine infusion. 3 The present study does not support our original hypothesis that salbutamol may be capable of suppressing the adrenal medulla in normal subjects.
D000284:Administration, Oral; D000313:Adrenal Medulla / Q000187:drug effects* / Q000502:physiology; D000328:Adult; D000420:Albuterol / Q000008:administration & dosage / Q000494:pharmacology*; D004837:Epinephrine / Q000097:blood; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D008297:Male
D006632:Histamine; D000420:Albuterol; D004837:Epinephrine