title: [Clinical and anatomopathological course of cancer starting in the vocal cords. Results of treatment].
abstract: Histological examination of serial sections from 127 cases of precancerous lesions and 86 cases of early cancer of the vocal cords was conducted. A histological precancerous state was observed: cellular dysplasia. Analysis of progression of cancer of the vocal cords showed 4 different varieties of carcinogenesis: one sudden, one progressive, one by proliferation and one by transformation. Functional conservative surgery of a glottic cancer had been performed in 76.7 p. cent of cases, and cobalt therapy applied in 23.3 p. cent. Recurrence rate was 6.1 p. cent after surgery and 30.0 p. cent after irradiation. Recovery occurred in 75.6 p. cent after surgery and 65.0 p. cent after irradiation. Precancerous lesions were treated by conservative operations and by microsurgery.
mesh_terms: D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D007825:Laryngectomy; D008297:Male; D009364:Neoplasm Recurrence, Local; D011230:Precancerous Conditions / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D014827:Vocal Cords / Q000473:pathology
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Evolution clinique et anatomo-pathologique du cancer débutant des cordes vocales. Résultats du traitement.