On the origin of the compound action potentials (N1, N2) of the cochlea of the rat.
The origin of N2 component of the compound action potential was studied by comparing the potential recorded at the round window with the response recorded from the cochlear nucleus, by comparing the potential recorded at the round window before and after the cochlear nucleus was removed by suction, and by comparing latencies of unit responses from auditory nerve fibers and cochlear nucleus units with the responses from the round window. The results indicated that the N2 potential, as well as the positive potential between the N1 and N2, was generated by secondary auditory neurons situated in the cochlear nucleus. The results were based on the response to click sounds and cross correlograms of the response to continuous sounds that were amplitude-modulated with pseudorandom noise.
D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D003051:Cochlea / Q000502:physiology*; D003056:Cochlear Nerve / Q000502:physiology; D005072:Evoked Potentials, Auditory; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000502:physiology; D012405:Round Window, Ear / Q000502:physiology