[Kala-azar in childhood. 20 year review].
Authors have reviewed 43 patients with Kala-azar admitted to hospital from 1960 to 1980. Thirty two patients came from Madrid province and rest from surroundings. There was a male predominance. Disease was more common between children under two years old. Bone marrow examination was positive for parasites in 60% of patients and in the others diagnosis was established because an appropriate response to Antimonials. All patients were treated with N-metil-Glucamined and in two patients Neo-Stibosan was added later. Clinical response to treatment was to complete remission in all patients.
D000293:Adolescent; D000367:Age Factors; D000814:Aniline Compounds / Q000627:therapeutic use; D000965:Antimony / Q000627:therapeutic use; D001853:Bone Marrow / Q000469:parasitology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007891:Leishmania / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008536:Meglumine; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds; D012737:Sex Factors; D013030:Spain; D013267:Stilbenes / Q000627:therapeutic use
D000814:Aniline Compounds; D009942:Organometallic Compounds; D013267:Stilbenes; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony; C038310:neostibosan
Kala-azar en la infancia. Revisión de veinte años.