[Comparative kinetics of spleen cell-mediated antibody-dependent cytotoxic activity in mice treated with BCG or Mycobacterium smegmatis].
Spleen cells from C3H/HeN mice treated with BCG or Mycobacterium smegmatis displayed similar increased antibody-dependent cellular cytotoxicity (ADCC) in vitro. This activity, which increased between the tenth and the thirty-first day after stimulation, reached twice the amount of ADCC activity developed by the control spleen cells. C3H/HeN mice treated with a complete adjuvant including M. smegmatis and squalene displayed a lower increase in their ADCC capacity (30% instead of 100%).
D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D001500:BCG Vaccine / Q000008:administration & dosage* / Q000627:therapeutic use; D002452:Cell Count; D007700:Kinetics; D008214:Lymphocytes / Q000378:metabolism; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009161:Mycobacterium / Q000276:immunology*; D013154:Spleen / Q000166:cytology* / Q000276:immunology; D013185:Squalene / Q000008:administration & dosage
D001500:BCG Vaccine; D013185:Squalene
Cinétique comparée de l'activité cytotoxique anticorps-dépendante à médiation cellulaire splénique de souris traitées par le BCG ou Mycobacterium smegmatis.