[Mechanisms of regulation of high cardiac output in patients with hypertension (angiocardiographic study)].
To identify mechanism conditioning high cardiac output, an angiocardiographic study was conducted in 39 patients with essential hypertension. Increased stroke and cardiac output was found to be due to increased venous inflow, with inotropic condition of the hypertrophic myocardium being reduced in spite of enhanced general pumping function of the left ventricle. As arterial hypertension tended to stabilize and cardiac output declined, total peripheral resistance assumed the principal responsibility for its regulation, whereas at earlier stages of the disease it shows either normal, or even reduced levels, and venous inflow is the principal factor controlling cardiac and stroke output.
D000328:Adult; D000790:Angiocardiography; D001794:Blood Pressure; D002302:Cardiac Output; D002496:Central Venous Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D014655:Vascular Resistance
Mekhanizmy reguliatsii vysokogo serdechnogo vybrosa u bol'nykh gipettonicheskoĭ bolezn'iu (angiokardiograficheskoe issledovanie).