title: Noninvasive CT diagnosis of infantile Alexander disease: pathologic correlation.
abstract: Noninvasive computed tomography provided the initial, accurate diagnosis of a necropsy-proven case of infantile Alexander disease, demonstrated serial changes in the intensity and distribution of leukodystrophy, and documented a progressive alteration of brain density from abnormally high attenuation to abnormally low attenuation as the disease advanced.
mesh_terms: D001706:Biopsy; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D007968:Leukoencephalopathy, Progressive Multifocal / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed