title: [Pathogenesis of laryngeal cancer in women. A clinical and follow-up study].
abstract: Clinical findings and age distribution of 71 female patients with laryngeal cancer seen in the ENT department of the University of Münster between 1961 and 1981 are reported. Of these patients, 26 could be questioned with regard to their habit of smoking and relevant gynaecological biographical data. They were compared with an equal number of patients of the same age not suffering from hormone-dependent diseases. With regard to histology, localisation or TNM staging, no signs of laryngeal cancer in women could be found compared to male patients reported in the literature. From the data gathered by questioning, it is possible to conclude that certain trends are represented, suggesting two pathogenetic types of laryngeal cancer in women: 1. Cancer of a young, non-smoking woman, showing signs of virilism. 2. Cancer of an older, smoking woman without signs of virilism.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000209:etiology* / Q000473:pathology; D007830:Larynx / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D012907:Smoking; D014770:Virilism / Q000150:complications
vernacular_title: Zur Pathogenese des Larynxkarzinoms bei Frauen. Eine klinische und anamnestische Untersuchung.