title: Variation between homologues and sister chromatids in individual karyotypes.
abstract: Chromatid absolute length and density profile from electron micrograph images of human group A chromosomes were studied in an attempt to identify significant individual karyotypic variation. The variation within sister chromatids can be utilized as an internal standard to establish a limit of variability for the purpose of demonstrating differences between homologues. Homologous chromosomes were found to differ with respect to absolute length and density profile.
mesh_terms: D002842:Chromatids / Q000648:ultrastructure*; D002900:Chromosomes, Human, 1-3 / Q000648:ultrastructure*; D014644:Genetic Variation; D006801:Humans; D007621:Karyotyping; D008854:Microscopy, Electron