Lack of estradiol receptor in Kurloff cell cytosol.
The percentage of lymphoid cells containing Kurloff bodies is increased after estrogen treatment. Cytosolic fractions of pure Kurloff cells were incubated with tritiated 17 beta-estradiol. No measurable specific binding was observed under any of the different experimental conditions tested. Kurloff cells do not appear to be a target cell for estrogen.
D000818:Animals; D003600:Cytosol / Q000032:analysis; D005260:Female; D006168:Guinea Pigs; D008214:Lymphocytes / Q000032:analysis*; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000032:analysis*; D013154:Spleen / Q000032:analysis
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen