Half-life of murine IgE antibodies in the mouse.
The half-life of intravenously injected murine anti-DNP IgE antibody was determined in recipient mice by sequential bleeding and was found to be 12 h. Intradermally injected IgE antibody persisted much longer, the half-life was 6 days.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000032:analysis*; D004136:Dinitrobenzenes / Q000276:immunology; D006207:Half-Life; D007073:Immunoglobulin E / Q000008:administration & dosage / Q000032:analysis*; D007271:Injections, Intradermal; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D051381:Rats; D011919:Rats, Inbred Strains
D000911:Antibodies, Monoclonal; D004136:Dinitrobenzenes; D007073:Immunoglobulin E