Malignant hypertension in women aged 15 to 44 years and its relation to cigarette smoking and oral contraceptives.
To study the factors associated with malignant hypertension in young women, we reviewed the medical records of all women aged 15 to 44 years who were hospitalized in any of 15 affiliated hospitals from 1971 to 1980 with malignant hypertension. There were 15 new patients in this period, an incidence of 0.5 per 100,000 women of these ages per year. Four women had underlying renal disease. All of the remaining 11 used oral contraceptives, smoked cigarettes, or both. Nine were white, and 6 women had normal blood pressure in the 24 months before hospitalization. These findings support a relation of oral contraceptive use and cigarette smoking to an increased risk of malignant hypertension in young women.
D000293:Adolescent; D000328:Adult; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000209:etiology*; D012306:Risk; D012907:Smoking
D003276:Contraceptives, Oral