[Effect of serotonin on the flow of intestinal contents in the proximal region of the ileum in the dog].
In chronic experiments on dogs, the i. v. and s. c. administration of serotonin in different doses changed the speed of contents passage in the proximal part of ileum. I. v. injection of serotonin induced phasic changes of contents passage in the small intestine: stimulation--inhibition--stimulation. No such obvious reactions occurred after s. c. injection of this amine. The duration and intensity of small intestine responses depended on its initial functional state at the moment of injection, dose and the way of drug administration.
D000818:Animals; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005769:Gastrointestinal Motility; D007082:Ileum / Q000502:physiology*; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D012701:Serotonin / Q000502:physiology*
D012701:Serotonin
Vliianie serotonina na skorost' peredvizheniia soderzhimogo f proksimal'noĭ chasti podvzdoshnoĭ kishki u sobak.