The interaction of cells persistently infected with canine distemper virus with antiviral antibody and complement.
Cells persistently infected with canine distemper virus can be lysed by antibody and complement. This reaction is dependent upon the alternative complement pathway. In the absence of antiviral antibody, the virus-infected cells will activate the alternative complement pathway, although this will not produce cell lysis.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D002460:Cell Line; D002522:Chlorocebus aethiops; D003167:Complement Activation; D003176:Complement C3 / Q000378:metabolism; D003170:Complement Pathway, Alternative; D004217:Distemper Virus, Canine / Q000276:immunology* / Q000502:physiology; D004285:Dogs; D006168:Guinea Pigs
D000914:Antibodies, Viral; D003176:Complement C3