Determination of glucose-6-phosphate dehydrogenase levels in red cell preparations.
Data are presented which prove that accurate measurement of glucose-6-phosphate dehydrogenase (G6PD) activity in red cells can be affected by the presence of leukocytes and platelets. Measurement of the enzyme in red cell preparations (after buffy coat removal) permits more accurate identification of patients with deficient enzyme activity, especially in the presence of anemia and/or leukocytosis.
D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D010976:Platelet Count; D011933:Reagent Kits, Diagnostic
D006454:Hemoglobins; D011933:Reagent Kits, Diagnostic; D005954:Glucosephosphate Dehydrogenase