title: Urinary corticoids in the diagnosis of canine hyperadrenocorticism.
abstract: In 20 healthy experimental dogs the 24 hour urinary corticoid excretion as measured by cortisol radioimmunoassay on two consecutive days varied from 0.5 to 3.3 nmol/kg/24 hours and from 0.3 to 3.6 nmol/kg/24 hours. In 20 dogs with otherwise proven spontaneous hyperadrenocorticism these values varied from 4.4 to 35.7 nmol/kg/24 hours and from 3.6 to 26.8 nmol/kg/24 hours respectively. Corticoid/creatinine ratios in morning urine samples of 28 healthy pet dogs were 1.2 to 6.9 X 10(-6). In 27 dogs with spontaneous hyperadrenocorticism all ratios exceeded the range observed in the healthy pet dogs.
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D003404:Creatinine / Q000652:urine; D003480:Cushing Syndrome / Q000175:diagnosis / Q000652:urine / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000652:urine; D004285:Dogs; D005260:Female; D006854:Hydrocortisone / Q000652:urine*; D008297:Male; D011863:Radioimmunoassay / Q000662:veterinary; D012016:Reference Values
chemical_list: D003404:Creatinine; D006854:Hydrocortisone