title: [Proglumetacin for fast and safe control of joint pain of orthopedic importance].
abstract: Thirty patients with articular pain had been treated with proglumetacin during average 12 days. Twenty-three (77%) responded well to very well to the treatment. Total symptom score decreased by 49%, and each tested symptom (painful, inflammatory and functional) significantly improved, in spite of the short observation period. Tolerance was defined good to excellent in 26 patients (87%). Overall, 10 patients complained of mild to moderate accessory symptoms, mainly heartburn and epigastric pain. No C.N.S. symptoms were observed, nor variations of the laboratory tests, carried out in 16 patients. Proglumetacin, therefore, showed to be a suitable drug for the fast and safe management of articular pain of orthopedic interest.
mesh_terms: D000328:Adult; D000368:Aged; D001132:Arm; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D006225:Hand; D006801:Humans; D007210:Indoleacetic Acids / Q000627:therapeutic use*; D007592:Joint Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D013122:Spinal Diseases / Q000188:drug therapy
chemical_list: D007210:Indoleacetic Acids; C019541:proglumetacin
vernacular_title: La proglumetacina per un controllo rapido e sicuro delle artralgie di interesse ortopedico.