Psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans.
Recent research with animals has indicated a central nervous system effect on the immune system. This report describes findings of a possible psychologically mediated effect on the delayed hypersensitivity reaction to tuberculin in humans. Seven tuberculin positive subjects evidenced a decreased response to tuberculin (as measured by erythema and induration) when a paradigm similar to behavioral conditioning was followed where the subjects expected their reactions to be negative.
D003213:Conditioning, Psychological; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000523:psychology*; D012718:Set, Psychology; D014373:Tuberculin / Q000276:immunology; D014374:Tuberculin Test
D014373:Tuberculin