Observations on the morphology and electrophoretic variation of enzymes of the rodent malaria parasites of Cameroon, Plasmodium yoelii, P. chabaudi and P. vinckei.
Six samples of rodent blood infected with malaria parasites were isolated from Cameroon. Of these, 2 contained mixed infections of Plasmodium vinckei and P. yoelii, 3 contained P. vinckei alone and 1 P. chabaudi alone. Each isolate was cloned and the resulting lines examined for morphology of blood and mosquito forms, and for electrophoretic variation in enzymes. The P. chabaudi and P. yoelii lines were morphologically and enzymically identical to isolates of the Central African Republic. Similarly, 1 P. vinckei line was identical to an isolate of the Central African Republic. The remaining 4 P. vinckei lines showed considerable variation, some enzymes being like those in isolates of surrounding regions, while others were unique to Cameroon.
D000818:Animals; D002163:Cameroon; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000469:parasitology; D005956:Glucose-6-Phosphate Isomerase / Q000032:analysis; D005969:Glutamate Dehydrogenase / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008288:Malaria / Q000469:parasitology / Q000662:veterinary*; D010734:Phosphogluconate Dehydrogenase / Q000032:analysis; D010961:Plasmodium / Q000145:classification / Q000166:cytology* / Q000201:enzymology; D012376:Rodent Diseases / Q000469:parasitology*; D012377:Rodentia / Q000469:parasitology
D007770:L-Lactate Dehydrogenase; D010734:Phosphogluconate Dehydrogenase; D005969:Glutamate Dehydrogenase; D005956:Glucose-6-Phosphate Isomerase