title: Adult respiratory distress syndrome following thrombolytic therapy for pulmonary embolism.
abstract: Pulmonary edema is rare in patients with pulmonary embolism and to our knowledge has not been described in association with thrombolytic therapy. We describe a patient with massive pulmonary embolism in whom the adult respiratory distress syndrome (ARDS) developed shortly after a course of streptokinase therapy. The possible association between streptokinase therapy or pulmonary embolism and ARDS should be recognized as streptokinase gains wider clinical use.
mesh_terms: D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D011654:Pulmonary Edema / Q000139:chemically induced; D011655:Pulmonary Embolism / Q000188:drug therapy*; D012128:Respiratory Distress Syndrome / Q000139:chemically induced* / Q000473:pathology; D013300:Streptokinase / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D013300:Streptokinase