title: [The effect of hyposensitization in bronchial asthma of childhood with regard to the histamine reactivity of the bronchial tract].
abstract: 86 children with asthma were re-examined after receiving hyposensitization for a period of two years. A measurable decrease in the bronchial hypersensitivity was recorded in 40 patients. The group of children suffering from asthma during the grass pollen season showed a more favourable result, compared to patients with perennial asthma. 16 patients demonstrated an unchanged histamine response. The bronchial hypersensitivity was increased in 30 patients. Personally interviewed, 39.5% indicated a notable improvement, 55.8% no change and 4.7% a deterioration. There was no significant change in the bronchial hypersensitivity to histamine following hyposensitization. Only in some cases there was a correlation between the results of bronchial hypersensitivity and the subjective changes.
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D001985:Bronchial Provocation Tests; D002648:Child; D003888:Desensitization, Immunologic; D006632:Histamine / Q000008:administration & dosage; D006801:Humans; D012221:Rhinitis, Allergic, Perennial / Q000628:therapy; D006255:Rhinitis, Allergic, Seasonal / Q000628:therapy
chemical_list: D006632:Histamine
vernacular_title: Uber die Wirksamkeit der Hyposensibilisierung bei Asthma bronchiale im Kindesalter unter Berücksichtigung der Histaminreagibilität des Bronchialsystems.