[Degenerative changes in the occipital neocortex in chronically amphetamine treated rats].
Neurons of the Wistar-rats' occipital cortex were morphologically investigated after chronical application of amphetamine. The nerve cells impregnated according to the Golgi-Kopsch technique showed in part changes on both the dendrites and in the axonal region. Besides a partial reduction of spines and of peripheral dendritic arborizations round varicosities of different density could be observed on the dendrites and on the axon, either, which were discussed to be due to a neurotoxic effect of amphetamine.
D000661:Amphetamine / Q000009:adverse effects*; D000818:Animals; D001369:Axons / Q000187:drug effects; D003712:Dendrites; D008297:Male; D009410:Nerve Degeneration / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects; D009778:Occipital Lobe / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains
D000661:Amphetamine
Degenerative Veränderungen im occipitalen Neocortex chronisch mit Amphetamin behandelter Ratten.