title: [Effect of peritol on the functional and morphological characteristics of the small intestine in rats].
abstract: Experiments were made on 140 male Wistar rats with the use of morphological, biochemical and radiometric research methods. It was established that as soon as the treatment with the anabolic drug peritol was completed, there appeared the morphological signs attesting to an increase in functional activity of vasculostromal elements of the small intestine, and the absorption rate of vitamin B12 got intensified. Activity of enzymes responsible for parietal digestion (alkaline phosphatase, invertase), absorption of 59Fe-citrate and 131I-albumin were unchanged. No substantial changes were revealed on the part of the morphology and function of the small intestine in the long-term period after peritol administration.
mesh_terms: D000818:Animals; D003533:Cyproheptadine / Q000494:pharmacology*; D007408:Intestinal Absorption / Q000187:drug effects; D007413:Intestinal Mucosa / Q000187:drug effects / Q000648:ultrastructure; D007421:Intestine, Small / Q000187:drug effects* / Q000503:physiopathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains; D012702:Serotonin Antagonists / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D012702:Serotonin Antagonists; D003533:Cyproheptadine
vernacular_title: Vliianie peritola na funktsional'nye i morfologicheskie kharakteristiki tonkoĭ kishki krys.