The alkylacyl and alkenylacyl glycerophospholipids of human platelets.
The phospholipids of human platelets were isolated and analysed for their constituent 1-0-alkyl- and 1-0-(1'-alkenyl)glycerol species. The serine and inositol phospholipids contained only small amounts (0.5-1.6%) of both alkylacyl and alkenylacyl species; the ethanolamine phospholipids contained little alkylacyl (1.7%) but much more alkenylacyl (45.3%) species, while the choline phospholipids contained 4.5% and 1.4% of these compounds, respectively. Because choline phospholipids amount to 41% of the total phospholipids of human platelets, it appears that they could provide a sufficient supply of alkylacyl glycerophosphocholine for the generation of the alkylacetyl analog (platelet activating factor) by a deacylation-acetylation pathway.
D001792:Blood Platelets / Q000032:analysis*; D005994:Glycerophosphates / Q000097:blood; D006801:Humans; D010712:Phosphatidic Acids / Q000097:blood*; D010713:Phosphatidylcholines / Q000097:blood; D010714:Phosphatidylethanolamines / Q000097:blood; D010716:Phosphatidylinositols / Q000097:blood; D010718:Phosphatidylserines / Q000097:blood; D010743:Phospholipids / Q000097:blood*
D005994:Glycerophosphates; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010718:Phosphatidylserines; D010743:Phospholipids