title: Effect of physical training on exercise-induced bronchoconstriction.
abstract: A 6-week period of physical training of 28 asthmatic children reduced the exercise-induced percentage fall in peak expiratory flow (from baseline) from 44 +/- 4% (mean +/- SE) to 30 +/- 4%. Resting pulmonary function was unchanged. Resting and maximum heart rate (submaximal treadmill running) and postexercise plasma lactate were all lowered by training. The individual values for exercise-induced bronchoconstriction and postexercise plasma lactate correlated positively before and after training. Furthermore, the training-induced reduction in these parameters correlated. In 14 asthmatic children, who served as controls, exercise-induced bronchoconstriction and physical fitness remained unchanged during a comparable period. The study demonstrates a beneficial effect of endurance training on exercise-induced bronchoconstriction and working capacity.
mesh_terms: D001249:Asthma / Q000628:therapy*; D001250:Asthma, Exercise-Induced / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D001980:Bronchi / Q000503:physiopathology; D002648:Child; D005081:Exercise Therapy; D005260:Female; D006173:Gymnastics; D006339:Heart Rate; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D010806:Physical Education and Training; D010807:Physical Endurance; D012129:Respiratory Function Tests; D014938:Work Capacity Evaluation
chemical_list: D007773:Lactates