Unusual cardiovascular manifestations in a case of pheochromocytoma.
A case of proven pheochromocytoma is reported of a patient who presented with attacks of apparent hypotension, pulmonary edema, and myocardial injury with typical ECG and enzyme change. In spite of unmeasurably low peripheral blood pressure recordings during the attack, central aortic pressure was well above 240/140 mmHg. A clinical shocklike state was in effect due to severe arterial vasoconstriction. The pulmonary artery pressure was 48/26 mmHg during attacks, wedge pressure was 26 mmHg, and cardiac index 1.8 liters/min/m2. The coronary angiogram showed abnormal pooling of dye in the myocardial capillary network. It is concluded that: (1) Apparent hypotensive episodes in pheochromocytoma may be misleading and central arterial measurements may be needed to demonstrate the hypertensive crisis. (2) The abnormal coronary angiogram in our patient may be due to myocardial necrosis and damage to the intact arteriolar and microvascular system of the myocardium.
D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging*; D000328:Adult; D006801:Humans; D007022:Hypotension / Q000175:diagnosis; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis; D010673:Pheochromocytoma / Q000000981:diagnostic imaging*; D011654:Pulmonary Edema / Q000175:diagnosis; D011859:Radiography