Desipramine and methylphenidate combination treatment for depression: case report.
The authors successfully treated a chronically depressed man with a combination of desipramine and methylphenidate. Methylphenidate did not change his serum desipramine level, and the authors speculate that its ability to potentiate tricyclic responsiveness may be due to its dopaminergic activity.
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy*; D003891:Desipramine / Q000627:therapeutic use*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*
D008774:Methylphenidate; D003891:Desipramine