The mechanisms of amino acid uptake by Brugia pahangi in vitro.
The transcuticular uptake of L-glycine and L-arginine by adult female Brugia pahangi has been shown to involve both a saturable carrier transport system and diffusion. The uptake of L-glycine was competitive with regard to L-methionine, L-valine, and L-phenylalanine but noncompetitive with L-arginine. It is suggested that at least two distinct loci are involved in the transcuticular movement of amino acids in this filarial nematode.
D000818:Animals; D001120:Arginine / Q000378:metabolism* / Q000494:pharmacology; D001692:Biological Transport / Q000187:drug effects; D002009:Brugia / Q000378:metabolism*; D005260:Female; D005370:Filarioidea / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D007700:Kinetics; D008715:Methionine / Q000494:pharmacology; D010649:Phenylalanine / Q000494:pharmacology; D014633:Valine / Q000494:pharmacology
D010649:Phenylalanine; D001120:Arginine; D008715:Methionine; D014633:Valine; D005998:Glycine