title: [Correlation of the level of humoral cytotoxins and delayed hypersensitivity skin reactions with survival of patients with melanoma of the skin].
abstract: The study was concerned with relationships between blood-humoral cytotoxin level, time-delayed hypersensitivity skin reaction to DNCB and 3- and 5-year survival in skin melanoma patients. Humoral cytotoxin level proved to be irrelevant for prognosis, although this index may be sometimes used as a supplementary criterion for evaluating immunocompetence. Skin reactions to DNCB provide a valuable prognostic means in skin melanoma patients: 3- and 5-year survival rates are significantly higher in patients showing positive reaction than in those with negative reaction.
mesh_terms: D000328:Adult; D000368:Aged; D000917:Antibody Formation / Q000187:drug effects; D003603:Cytotoxins / Q000097:blood*; D004137:Dinitrochlorobenzene; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D008545:Melanoma / Q000276:immunology*; D008875:Middle Aged; D011379:Prognosis; D012878:Skin Neoplasms / Q000276:immunology*; D012882:Skin Tests
chemical_list: D003603:Cytotoxins; D004137:Dinitrochlorobenzene
vernacular_title: O korreliatsii urovnia gumoral'nykh tsitotoksinov i kozhnykh reaktsiĭ zamedlennoĭ giperchuvstvitel'nosti s vyzhivaemost'iu bol'nykh melanomoĭ kozhi.