[Comparison of 3 corticoid preparations with the vasoconstriction and erythema test].
The efficacy of a new topic preparation of the corticosteroid Halcinonide containing 5% Urea has been examined and then compared with two commercial preparations of Halcinonide and Betamethasonevalerate respectively. Although these two corticosteroids usually do not belong to the same class of potency, there could not be found any significant difference neither with the vasoconstriction assay nor with the Pyrexal erythema. The influence of the three most important parameters, that are vehicle, occlusion and skin condition, is a subject of discussion.
D000287:Administration, Topical; D000328:Adult; D001623:Betamethasone / Q000031:analogs & derivatives*; D001624:Betamethasone Valerate / Q000494:pharmacology*; D006206:Halcinonide / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011282:Pregnenediones / Q000494:pharmacology*; D012867:Skin / Q000098:blood supply*; D014661:Vasoconstriction / Q000187:drug effects*
D011282:Pregnenediones; D001623:Betamethasone; D001624:Betamethasone Valerate; D006206:Halcinonide
Vergleich dreier Kortikoidpräparate mit Vasokonstriktions- und Erythemtest.