Immunonephelometric quantitation of apolipoprotein E in human serum.
A laser immunonephelometric procedure for the determination of apolipoprotein E in human serum and lipoprotein fractions was developed. Coefficients of variation were 2.3% within-run, 4.7% between-run. The distribution of apolipoprotein E in various lipoprotein fractions revealed a higher proportion of apolipoprotein E in VLDL in hypertriglyceridaemic subjects (especially marked in Type III patients) than in normal subjects. Laser immunonephelometry appears suitable for the routine measurement of apolipoprotein E.
D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D001057:Apolipoproteins E; D006801:Humans; D007120:Immunochemistry / Q000379:methods; D008027:Light; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000379:methods; D012542:Scattering, Radiation
D001053:Apolipoproteins; D001057:Apolipoproteins E