Hypertension with renal carcinoma. An effect of arterial embolization.
A patient presented with mediastinal metastases from renal adenocarcinoma. Palliative therapy included Gelfoam and steel coil embolization of the right renal artery. Six weeks later he was found to have developed severe hypertension. Arteriogram revealed collateral vessels which supplied the tumor; the renal vein renin activity was four times higher on the right than on the left. We suspect that infarction of the kidney was not complete because of collateral arterial supply, and renin-dependent hypertension was the result. Thus, it may be hazardous to embolize large hypernephromas without subsequent nephrectomy.
D000230:Adenocarcinoma / Q000150:complications* / Q000628:therapy; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology*; D007680:Kidney Neoplasms / Q000150:complications* / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008479:Mediastinal Neoplasms / Q000556:secondary; D008875:Middle Aged; D012077:Renal Artery