title: Dysgerminoma of the ovary in association with XY gonadal dysgenesis.
abstract: A case is reported of an adolescent presenting with primary amenorrhea. On pelvic examination a large unilateral ovarian tumor was palpated. Microscopic examination of the tumor removed at laparotomy revealed a pure dysgerminoma. Further gynecological-endocrinological investigations and chromosome analysis showed an XY gonadal dysgenesis. A review of current approaches to diagnosis, prognosis and especially to the controversial therapeutic modalities is presented.
mesh_terms: D000293:Adolescent; D004407:Dysgerminoma / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006059:Gonadal Dysgenesis / Q000601:surgery*; D006061:Gonadal Dysgenesis, 46,XY / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000601:surgery*