title: [Results of radiotherapy in case of juvenile xanthogranuloma of the iris].
abstract: The juvenile xanthogranuloma is a rare, benign, cutaneous disease occurring in infants and young children which can be situated in about 10% of the cases on the eye and preferentially on the iris. The reason for consulting an ophthalmologist is mostly a recurrent unilateral hyphemia which is typical for this disease. The diagnosis of the juvenile xanthogranuloma has to be established clinically, based on the characteristic alterations of the iris--heterochromia, vascularized tumor or diffuse thickening of the iris--and the possibly increased intraocular pressure. In order to avoid the deleting consequences of an uncontrollable secondary glaucoma, radiotherapy with a total dose of 300 to 400 cGy combined with a mild local steroid treatment has to be undertaken immediately, if possible. Taking into consideration the indications of literature, the value of a low-dose radiotherapy for this disease shall be demonstrated by five own cases in all of which the concerned eye could be healed and preserved.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006099:Granuloma / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D007223:Infant; D007499:Iris Diseases / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D011879:Radiotherapy Dosage
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Ergebnisse der Strahlentherapie bei juvenilen Xanthogranulomen der Iris.