The effect of sleep deprivation and recovery sleep on plasma corticosterone in the rat.
The effect of 24-h sleep deprivation by forced locomotion on plasma corticosterone was investigated in the rat. Corticosterone was slightly elevated after 21.5 h sleep deprivation, but did not differ from controls after a 2.5-h recovery period. An acute 20-min forced locomotion period caused a marked rise in plasma corticosterone. It is concluded that stress is not a major factor contributing to the massive effects of sleep deprivation on sleep parameters.
D000818:Animals; D002940:Circadian Rhythm; D003345:Corticosterone / Q000097:blood*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation / Q000502:physiology*
D003345:Corticosterone