Power deposition patterns in magnetically-induced hyperthermia: a two-dimensional low-frequency numerical analysis.
The electric fields and power deposition patterns generated in two-dimensional inhomogenous models exposed to the axially directed uniform magnetic fields of an infinitely long solenoid are calculated numerically. The fields are calculated using the method of moments (Galerkin procedure) with linear basis and weighting functions. This low-frequency analysis is useful for studying the power deposition patterns attributable to solenoidal inductive applicators operated at frequencies up to 13.56 MHz. For the models we have studied, the ratio of power per volume deposited into the tumor to power per volume deposited into the immediately surrounding tissue is largest for tumors in the lung, although the power per volume deposited into the outermost layer is still much larger than the power per volume deposited into the tumor; it may be possible, however, to cool this region adequately from the body surface. When the complex permittivity of the tumor model is similar to that of the region in which it is embedded, the currents in the torso and tumor circulate primarily around the center of the body, as has been previously calculated for concentric cylinders. When the complex permittivity of the tumor is much greater than the region in which it is embedded, the currents in the tumor circulate primarily around the center of the tumor.
D003972:Diathermy / Q000379:methods; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D008280:Magnetics; D008433:Mathematics; D008954:Models, Biological; D008961:Models, Structural; D009369:Neoplasms / Q000628:therapy*