title: Cyclic hydrazides. V - synthesis and antiinflammatory activity of derivatives of the 2-amino-1,4-dihydroisoquinolin-3(2H)-one.
abstract: The synthesis of the 2-amino-1,4-dihydroisoquinolin-3(2H)-one (II a) and of some of its derivatives starting from the o.methylphenylacetic acid, is described. Some of the described compounds possess a moderate antiinflammatory activity.
mesh_terms: D000634:Aminoquinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000634:Aminoquinolines; D000893:Anti-Inflammatory Agents