Effects of propranolol on blood lipids and lipoproteins in myocardial infarction.
The effects of propranolol on lipids and lipoproteins were investigated in survivors of a recent myocardial infarction who were enrolled in the double-blind Beta-Blocker Heart Attack Trial. Nonfasting serum samples were obtained in more than 2800 patients assigned randomly to either propranolol or placebo. The propranolol-treated group had high-density lipoprotein cholesterol levels 3-4 mg/dl less and triglyceride concentrations 30-40 mg/dl higher than the placebo group. These effects occurred in men and women in all age categories.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000517:prevention & control; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism*; D011433:Propranolol / Q000627:therapeutic use*; D011897:Random Allocation; D014280:Triglycerides / Q000097:blood*
D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol; D011433:Propranolol