The nature of the Ln3+-angiotensin II complex. A 13C nmr study of the binding of Yb3+ to angiotensin II.
The nature of the Yb3+-angiotensin II complex is examined by 13C nuclear magnetic resonance. The ytterbium-induced shifts of most resonances are observed to be strongly dependent on pD, while a few are observed to be largely independent of pD. These observations are shown to be consistent with stepwise binding of the lanthanide ion to the carboxylates of aspartic acid and the C-terminus.
D000804:Angiotensin II; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008674:Metals, Rare Earth; D015018:Ytterbium
D008674:Metals, Rare Earth; D000804:Angiotensin II; D015018:Ytterbium