title: Seasonal variations of total histamine in patients with seasonal allergic rhinitis.
abstract: Seasonal variations of total blood histamine were examined in twenty patients with seasonal allergic rhinitis (Japanese cedar pollinosis). In blood specimens taken in the pollen season of 1978, the symptom-free season of 1978, and the pollen season of 1979, the mean values of blood histamine were 61.6, 50.0 and 84.2 ng/ml respectively. The differences in blood histamine levels between the pollen season of 1978 and the symptom-free season of 1978 and between the symptom-free season of 1978 and the pollen season of 1979 were statistically significant. In the symptom-free season of 1978, the blood histamine levels of twenty normal subjects were also examined; the mean value was 58.2 ng/ml. The blood histamine levels of the patients in the symptom-free season were not statistically different from those of the normal subjects.
mesh_terms: D000328:Adult; D002648:Child; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005453:Fluorescence; D006632:Histamine / Q000097:blood*; D006639:Histidine / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000097:blood*; D012621:Seasons; D013095:Spermidine / Q000032:analysis
chemical_list: D006639:Histidine; D006632:Histamine; D013095:Spermidine