Effect of temperature variation on sister chromatid exchange frequency in cultured human lymphocytes.
The effect of temperature variation on sister chromatid exchange (SCE) frequencies in human lymphocytes was studied. An increase as well as decrease in incubation temperature of cells leads to a higher frequency of sister chromatid exchanges than in cultures grown at 37 degrees C. In addition, it was observed that mitotic index and cell cycle duration were affected by low temperature.
D002453:Cell Cycle; D002478:Cells, Cultured; D003434:Crossing Over, Genetic; D006801:Humans; D007700:Kinetics; D008214:Lymphocytes / Q000502:physiology*; D008940:Mitotic Index; D012854:Sister Chromatid Exchange; D013696:Temperature