[Method of continuous quantitative recording of gastric acid levels in the stomach].
The author describes a method for a quantitative recording of hydrochloric acid output in the stomach of an anesthetized rat in the course of gastric perfusion with a buffer solution. Describes in detail the design of an experimental set up, provides the magnitudes of basal and histamine- and pentagastrin-stimulated gastric secretion of acid. Discusses different schemes of applying the method to exploring the action of stimulants and inhibitors of acid secretion in the stomach.
D000818:Animals; D005744:Gastric Acid / Q000378:metabolism*; D005745:Gastric Acidity Determination / Q000295:instrumentation*; D005753:Gastric Mucosa / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D008722:Methods; D010418:Pentagastrin / Q000494:pharmacology; D010477:Perfusion; D051381:Rats; D013268:Stimulation, Chemical; D013997:Time Factors
D006632:Histamine; D010418:Pentagastrin
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