Leydig cell tumor in patient on estrogen therapy.
The occurrence of a Leydig cell tumor in a sixty-nine-year-old man, who received estrogen therapy for approximately two and one-half years, is reported. No similar situation has been reported in the medical literature, although there has been a search for the cause of these tumors in man. Experimentally, the administration of estrogen has caused these tumors in mice.
D000230:Adenocarcinoma / Q000188:drug therapy; D000368:Aged; D004054:Diethylstilbestrol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007984:Leydig Cell Tumor / Q000139:chemically induced*; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000139:chemically induced*; D013997:Time Factors
D004054:Diethylstilbestrol