title: Mono (ADP-ribosyl)ation of hen liver nuclear proteins suppresses phosphorylation.
abstract: The phosphorylation of nuclear proteins from hen liver nuclei was suppressed under conditions of incubation with NAD. The reconstituted protein kinase assay system containing heat-treated and subsequently ADP-ribosylated nuclei and NI type protein kinase revealed that the ADP-ribosylated nuclear proteins are poor acceptors for the phosphorylation reaction. Therefore, mono(ADP-ribosyl)ation may contribute to the regulation of phosphorylation reaction in nuclei.
mesh_terms: D000246:Adenosine Diphosphate Ribose / Q000378:metabolism*; D000818:Animals; D002645:Chickens; D005260:Female; D006358:Hot Temperature; D008099:Liver / Q000378:metabolism*; D009698:Nucleoproteins / Q000378:metabolism*; D009702:Nucleoside Diphosphate Sugars / Q000378:metabolism*; D010766:Phosphorylation
chemical_list: D009698:Nucleoproteins; D009702:Nucleoside Diphosphate Sugars; D000246:Adenosine Diphosphate Ribose