[Threshold doses of Staphylococcus aureus and the dynamics of leukocyte phagocytic activity in relation to the concentration of the causative agent in the blood].
The study of the phagocytic characteristics of leukocytes at different concentrations of Staphylococcus aureus, carried out in 18 persons, has revealed that the mechanism of phagocytosis cannot be triggered only by the presence of the infective agent in the blood; to trigger this mechanism, the concentration of the infective agent in the blood must reach a definite liminal level (for S. aureus this level is 0.5 X 10(6) microbial bodies per ml). A further rise in the concentration of the infective agent leads to the increase of the efficiency of phagocytosis as indicated by a curve resembling the exponential logarithmic function. When the concentration of S. aureus in the blood exceeds 1 X 10(9) microbial bodies per ml, no essential effect on the increase of phagocytic characteristics is observed.
D000328:Adult; D003289:Convalescence; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000276:immunology*; D010587:Phagocytosis; D018805:Sepsis / Q000276:immunology* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000276:immunology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000472:pathogenicity*
O porogovykh dozakh zolotistogo stafilokokka i dinamike fagotsitarnoĭ aktivnosti leĭkotsitov v zavisimosti ot kontsentratsii vozbuditelia v krovi.