title: Alternariasis: ultrastructure of skin granuloma.
abstract: An ultrastructural investigation of dermal altenariasis has complemented previous studies. Alternaria tenuis was seen to be profusely present within the cytoplasm of multinucleate giant cells. Healthy elements were characterized by a thick, electron-lucent wall, ovoid osmiophilic inclusions and a poorly defined nucleus. Homogenous liquefaction and granular degeneration represented various types and steps of degradation; the wall subsisted for a while before collapsing and breaking into pieces. Penetration of the giant cell's cytoplasm within hollow tubes was observed.
mesh_terms: D000328:Adult; D000528:Alternaria / Q000648:ultrastructure; D003881:Dermatomycoses / Q000473:pathology*; D006644:Histiocytes / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000648:ultrastructure*