Treatment of the arthropathy of familial hypercholesterolaemia.
A 29-year-old woman suffering from the arthropathy of familial hypercholesterolaemia was treated with a fat-modified low-cholesterol diet and colestipol. Symptomatic improvement occurred in association with a moderate reduction in the plasma cholesterol concentration. The pathogenesis of the musculoskeletal features of this disease is reviewed, and the implications of this patient's therapeutic response are explored.
D000328:Adult; D001168:Arthritis / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D002784:Cholesterol / Q000097:blood; D003084:Colestipol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications* / Q000473:pathology
D002784:Cholesterol; D003084:Colestipol