[Morphometric study of the sclerocorneal trabeculum of rabbits after treatment with corticosteroids or hyaluronidase].
In eyes treated with corticosteroids the thickness of the trabecula is increased, the width of the intertrabecular spaces reduced and the number of trabecula per surface unit greater. In eyes perfused with hyaluronidase the opposite is seen, i.e., the thickness of the trabecular is reduced, the width of the intertrabecular spaces increased and the number of trabecula per surface unit diminished. The number of glycoproteins in the ground substance increases after treatment with corticosteroids while perfusion with hyaluronidase has the opposite effect. We have treated 27 rabbits, of which 17 with local administration of Dexamethasone 0,1%, 5 with subconjunctival injections and 5 as controls.
D000305:Adrenal Cortex Hormones / Q000494:pharmacology*; D000818:Animals; D003315:Cornea / Q000187:drug effects*; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D012590:Sclera / Q000187:drug effects*; D014129:Trabecular Meshwork / Q000187:drug effects* / Q000648:ultrastructure
D000305:Adrenal Cortex Hormones; D006821:Hyaluronoglucosaminidase
Morphometrische Untersuchung des sklerokornealen Trabekulums von Kaninchen nach Behandlung mit Kortikosteroiden oder Hyaluronidase.