A disturbance of serum lipids in three cases of Werner's syndrome.
3 cases of Werner's syndrome were studied on serum lipid metabolism in comparison with clinical manifestation. These 3 cases showed hyperlipemia all with hypertriglycemia and increased level of very low density lipoprotein. The lipoprotein lipase activity was shown after intravenous injection of heparin. These results indicate a possible pathogenic facet of Werner's syndrome from the lipid metabolic point of view.
D000328:Adult; D002114:Calcinosis / Q000150:complications; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D006951:Hyperlipoproteinemias / Q000150:complications; D007136:Immunoglobulins / Q000032:analysis; D008071:Lipoprotein Lipase / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D014898:Werner Syndrome / Q000097:blood* / Q000209:etiology
D007136:Immunoglobulins; D014280:Triglycerides; D008071:Lipoprotein Lipase