title: [Mechanism of the radiation damage to the secondary structure of DNA].
abstract: The authors describe the mechanism of radiation-induced damage of a secondary DNA structure suggesting that a double-helical brim conformation adjacent to a local defect in the secondary structure, and the thermoactivated threshold process of a "confluence" of the defects are present in the irradiated DNA. It is supposed that the major type of the radiation damage to the spatial DNA structure is a triple helix repaired with the aid of the specific endonuclease.
mesh_terms: D004247:DNA / Q000528:radiation effects*; D004260:DNA Repair / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D009690:Nucleic Acid Conformation / Q000528:radiation effects*; D013696:Temperature
chemical_list: D004247:DNA
vernacular_title: Mekhanizm radiatsionnogo narusheniia vtorichnoĭ struktury DNK.