title: Lamicel: a new technique for cervical dilatation before first trimester abortion.
abstract: Mechanical dilation of the cervix can be both difficult and dangerous and has potentially serious complications. Lamicel, a synthetic hydrophilic polymer, was inserted into the cervix between 2 and 24 h before termination by vacuum aspiration in the first trimester in 48 nulliparae. A control group of 12 nulliparae were not treated with Lamicel. The force needed to dilate the cervix, accurately measured with a specifically designed force-measuring instrument, was found to be significantly reduced in all treated groups. The greatest rate of dilatation occurred within the first 2 h after insertion.
mesh_terms: D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000502:physiology*; D004107:Dilatation and Curettage / Q000379:methods*; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate; D011142:Polyvinyl Alcohol; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011312:Pressure
chemical_list: C034860:Lamicel; D008278:Magnesium Sulfate; D011142:Polyvinyl Alcohol