Cortisol level response to 1- and 2-mg doses of dexamethasone.
Sixteen depressed patients underwent 1- and 2-mg overnight dexamethasone suppression tests in balanced order. Serum cortisol concentrations at all time points were significantly higher after the 1-mg dose. Nine patients were nonsuppressors after the 1-mg dose, and 4 after the 2-mg dose.
D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000097:blood / Q000175:diagnosis*; D003907:Dexamethasone / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged
D003907:Dexamethasone; D006854:Hydrocortisone