Preliminary evaluation of high-performance liquid chromatography with photoconductivity detection for the determination of selected pesticides as potential food contaminants.
The applicability of the Tracor Model 965 photoconductivity detector to the determination of a variety of pesticide chemicals, particularly polar and/or thermally labile compounds which are troublesome in gas chromatographic analysis, has been investigated. The effects of various operating parameters (e.g., mobile phase composition, flow-rate and irradiation wavelength) on signal-to-noise output for selected compounds have been evaluated. A comparison of photoconductivity responses with those obtained from a UV detector connected in tandem was made for selected reference standards and food sample extracts. The photoconductivity detector was found to be suitable for the determination of pesticide residues at sub-parts-per-million levels. The linearity and reproducibility of response are adequate for practical quantitative applications.
D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D010777:Photochemistry
D010573:Pesticide Residues