Comparative study of phenotypes on activity and plasma concentration in the genetic system of plasminogen.
Plasma antigen concentration of plasminogen was approximately 11-13 mg/100 ml in all phenotypes. Specific activities of common PLG 1-1 and second common PLG 2-1 were 16.52 +/- 1.43 U/mg (caseinolytic activity/milligram antigen concentration, mean +/- SD) and 17.22 +/- 2.14 U/mg, respectively. Caseinolytic activity, antigen concentration and specific activity of PLG 1-B were 0.80 +/- 0.23 U/ml, 11.39 +/- 2.44 mg/100 ml and 6.95 +/- 0.96 U/mg. Plasma plasminogen levels of three rare phenotypes (PLG 3-1, PLG 1-C and PLG 1-M) were at least in the normal ranges by immunological and biological assay.
D000483:Alleles; D000941:Antigens / Q000032:analysis; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007564:Japan; D008297:Male; D010958:Plasminogen / Q000172:deficiency / Q000235:genetics* / Q000276:immunology; D013927:Thrombosis / Q000209:etiology
D000941:Antigens; D010958:Plasminogen