[Effect of changes in electrolyte composition of the perilymph on endocochlear potentials].
Perfusion of the cochlear perilymphatic space was performed in guinea pigs with complete or partial removal of K+, Na+ or Ca++ from the solution. The most obvious changes of the endocochlear potential occurred in the deficiency of Na+ in the perilymph: i. e., after a short increase the potential steadily diminished in accordance with the degree of Na+ deficit in the perilymph. The deficit of K+ in the perilymph caused a lesser and reversible reduction of the potential. The absence of Ca++ in the perilymph did not affect the potential.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003051:Cochlea / Q000502:physiology*; D004573:Electrolytes / Q000378:metabolism*; D004710:Endolymph / Q000502:physiology; D006168:Guinea Pigs; D007761:Labyrinthine Fluids / Q000378:metabolism*; D008564:Membrane Potentials; D010477:Perfusion; D010498:Perilymph / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D004573:Electrolytes; D012964:Sodium; D011188:Potassium; D002118:Calcium
Vliianie izmeneniia élektrolitnogo sostava perilimfy na éndokokhlearnyĭ potentsial.