[Hemodynamics of the lesser circulation in prolonged hypokinesia (based on data from a morphological study)].
This paper presents data on pulmonary circulation of rats during prolonged hypokinesia (30 to 165 days). It was found that the hypokinetic exposure of 30 to 60 days produced venous and, in particular, capillary plethora associated with blood redistribution and pooling in the lungs. As the exposure continued, the plethora level decreased due to the development of compensatory-adaptive reactions in the lung vessels. For instance, on hypokinetic day 90 small arteries of the muscle type developed a spasm which accelerated circulation stabilization. By hypokinetic days 120-165 pulmonary circulation returned to normal due to the further development of compensatory-adaptive mechanisms in lung vessels (tendency for hypertrophy of the media of small arteries and increase of its cross-sectional area).
D000818:Animals; D002196:Capillaries / Q000473:pathology; D006439:Hemodynamics; D008168:Lung / Q000473:pathology; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology; D011652:Pulmonary Circulation; D011667:Pulmonary Veins / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical / Q000009:adverse effects*; D013997:Time Factors
K voprosu o sostoianii gemodinamiki malogo kruga krovoobrashcheniia pri dlitel'noĭ gipokinezii (po dannym morfologicheskogo issledovaniia).