A comparison between the combination emepronium bromide/flavoxate and emepronium bromide in the treatment of detrusor instability.
Emepronium bromide and flavoxate have both and separately been used with success in the treatment of detrusor instability. In this study we have combined the two drugs emepronium bromide and flavoxate and compared the results with emepronium bromide. 20 consecutive patients with an uninhibited bladder, 12 men and 8 women, were randomly allocated to treatment with either emepronium bromide/flavoxate or emepronium bromide. In this trial we found that treatment with the combination is significantly better than treatment with emepronium bromide only.
D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D004629:Emepronium / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005419:Flavonoids / Q000008:administration & dosage*; D005422:Flavoxate / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage*; D001745:Urinary Bladder Diseases / Q000188:drug therapy*; D014555:Urination Disorders / Q000188:drug therapy*
D005419:Flavonoids; D000644:Quaternary Ammonium Compounds; D004629:Emepronium; D005422:Flavoxate