title: An age dependent model for radium metabolism in man.
abstract: The model developed by a Task Group of Committee 2 of ICRP to describe Alkaline Earth Metabolism in Adult Man (ICRP Publication 20) has been modified so that recycling is handled explicitly, and retention in mineral bone is represented by second compartments rather than by the product of a power function and an exponential. This model has been extended to include all ages from birth to adult man, and has been coupled with modified "ICRP" lung and G.I. tract models so that activity in organs can be calculated as functions of time during or after exposures. These activities, and age dependent "specific effective energy" factors, are then used to calculate age dependent dose rates, and dose commitments. This presentation describes this work, with emphasis on the model parameters and results obtained for radium.
mesh_terms: D000375:Aging / Q000528:radiation effects*; D001842:Bone and Bones / Q000378:metabolism; D006801:Humans; D008673:Metals, Alkaline Earth / Q000378:metabolism; D008954:Models, Biological; D011829:Radiation Dosage; D011883:Radium / Q000378:metabolism*; D013997:Time Factors
chemical_list: D008673:Metals, Alkaline Earth; D011883:Radium