Nonfamilial Turcot's syndrome associated with Crohn's disease and duodenal ulcer in one kindred.
We report a case of Turcot's syndrome in a 56-year-old man with nonfamilial polyposis coli and Dukes C adenocarcinoma of the colon who later manifested a grade 3 astrocytoma of the brain. His daughter has well-documented Crohn's disease of the small and large bowel and his son suffered from a duodenal ulcer since the age of 7.
D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D001932:Brain Neoplasms / Q000235:genetics*; D003110:Colonic Neoplasms / Q000235:genetics*; D003424:Crohn Disease / Q000235:genetics*; D004381:Duodenal Ulcer / Q000235:genetics*; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013577:Syndrome