Effect of tiamulin administered by various methods and dosages on turkeys at different ages.
Healthy male turkeys not receiving monensin in their feed were treated with tiamulin by various methods and at different ages. Nine cycles of treatments were performed at the ages of 26, 40, 61, 89, 103, 117, 131, 145, and 160 days. Intramuscular of subcutaneous injections of 12.5 mg/kg tiamulin up to 145 days did not result in any signs of toxicity or impair growth rate. Administration at a dose of up to 25 mg/kg, using the drinking-water-deprivation technique, caused no effect in turkeys up to 160 days (marketing age).
D000284:Administration, Oral; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000633:toxicity; D001835:Body Weight / Q000187:drug effects; D004224:Diterpenes / Q000494:pharmacology / Q000633:toxicity; D004326:Drinking; D007273:Injections, Intramuscular / Q000662:veterinary; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D009026:Mortality; D014422:Turkeys / Q000502:physiology*
D000900:Anti-Bacterial Agents; D004224:Diterpenes; C014224:tiamulin