title: Esophagitis secondary to ingestion of caustic material.
abstract: The records of 176 patients admitted to Grady Memorial Hospital over a 10-year period with a history of ingestion of corrosive material were reviewed. Esophagoscopy was performed in 168 patients an average of 15 hours after ingestion. In 94 patients, no esophageal burn was found. Seventy-four others had injury of the esophagus of varying degree; 3 of these had no evidence of oropharyngeal burn. The patients with esophageal injury were treated with steroids for two weeks and antibiotics for 5 days. No complications resulted from esophagoscopy or steroid therapy in any patient. Stricture did not develop in any of the patients in whom esophagoscopy was negative. Documented stricture occurred in 29 patients with esophagoscopic evidence of esophageal burns, 7 of whom did not respond to periodic esophageal dilation and subsequently underwent esophageal bypass. Three patients had symptoms and signs of gastric perforation on the first, sixth, and eighth days after ingestion, respectively, and at laparotomy all of them were found to have severe gastric injury. One of these patients died on the postoperative day 28; this was the only death among all patients seen with history of ingestion of corrosive material. This study suggests that with early esophagoscopy, approximately 55% of patients who ingest corrosive material can be spared the agony and prolonged treatment of possible esophageal injury. Appropriate management will result in preservation of the esophagus in most patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002057:Burns, Chemical / Q000628:therapy*; D002424:Caustics / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004941:Esophagitis / Q000139:chemically induced* / Q000628:therapy; D004945:Esophagoscopy; D004947:Esophagus / Q000293:injuries*; D006801:Humans; D007223:Infant; D008875:Middle Aged
chemical_list: D002424:Caustics