[Effect of surgery and anesthesia on the plasma catecholamine level and rate of urea production in severely burned patients].
The influence of anaesthesia and operation on plasma catecholamine level (Group A) and on the production of urea (PU) (Group B) was investigated in two groups of severely burned patients. Plasma catecholamine levels increased at every operation. The increase of noradrenaline however was always higher than that of adrenaline. The elevation of NA in operations performed during the first week was significantly higher than in all later operations. The production of urea (PU) was chosen as a parameter of protein catabolism. The PU was measured on the day before the operation, on the operation day and on the 1st, 2nd and 3rd postoperative day. The highest mean values of the PU could be found on the 2nd and 3rd postoperative day, but the increase was less than expected. There was no difference in plasma catecholamine levels in PU between the different methods of anesthesia. The advantages and disadvantages of the methods of anaesthesia studied are discussed.
D000293:Adolescent; D000328:Adult; D000768:Anesthesia, General; D002056:Burns / Q000378:metabolism* / Q000601:surgery; D002395:Catecholamines / Q000097:blood*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000096:biosynthesis*
D002395:Catecholamines; D014508:Urea
Der Einfluss von Operation und Anaesthesie auf den Plasmakatecholaminspiegel und die Harnstoffproduktionsrate bei Schwerstverbrannten.