Platelet monoamine oxidase activity and trace acid levels in plasma of agoraphobic patients.
Platelet monoamine oxidase activity and plasma trace acid levels in 29 patients classified as agoraphobics was estimated. MAO activity towards p-tyramine and beta-phenylethylamine was found to be significantly higher in agoraphobics than in non-agoraphobic depressed patients and healthy controls. In addition plasma p-hydroxyphenylacetic acid levels were low in both agoraphobic and depressed patient groups. All patients were also assessed by Spielberger State Anxiety and the short form of the Beck Depression Inventory scales. No significant correlations could be found between platelet MAO activity or plasma trace acid levels and the psychological scores.
D000328:Adult; D000379:Agoraphobia / Q000201:enzymology* / Q000523:psychology; D000596:Amino Acids / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood*; D010627:Phenethylamines / Q000097:blood; D010648:Phenylacetates / Q000097:blood; D010698:Phobic Disorders / Q000201:enzymology*; D011581:Psychological Tests; D014439:Tyramine / Q000097:blood
D000596:Amino Acids; D010627:Phenethylamines; D010648:Phenylacetates; C029261:phenethylamine; C008070:4-hydroxyphenylacetic acid; D008995:Monoamine Oxidase; C025136:phenylacetic acid; C008069:3-hydroxybenzeneacetic acid; D014439:Tyramine