title: Hysterectomy facilitates proceptive behavior in rats.
abstract: The effects of hysterectomy on proceptive behavior were investigated using several doses of estradiol benzoate (EB) and progesterone (P) in female rats. One week after surgery, ovariectomized (OV) and ovariectomized-hysterectomized (OH) rats were given three daily injections of 1.0 or 2.0 micrograms EB followed by 0.5 mg P or oil on the fourth day and were tested for solicitation 4 hr later. The same animals received 1.0 or 2.0 micrograms EB plus 0.1 mg P, or 4.0 micrograms EB plus oil on the same schedule a week following the first test and were tested again. Ovariectomized-hysterectomized animals receiving 0.5 mg P, regardless of the EB dose, showed significantly higher solicitation scores than OV animals, but the scores of the EB-primed OV and OH rats receiving 0.1 mg P or oil vehicle did not differ.
mesh_terms: D000818:Animals; D002369:Castration; D004347:Drug Interactions; D004958:Estradiol / Q000008:administration & dosage; D005260:Female; D007044:Hysterectomy; D011374:Progesterone / Q000008:administration & dosage; D051381:Rats; D012726:Sexual Behavior, Animal / Q000502:physiology*; D014599:Uterus / Q000502:physiology*
chemical_list: D011374:Progesterone; D004958:Estradiol