title: Morphology of experimental actinomycotic abscess in mice with Dermatophilus-like microorganisms from porcine tonsil.
abstract: Experimental infection in mice with Dermatophilus (D.) congolensis-like microorganisms was carried out, intraperitoneally and subcutaneously. This strain had been isolated from porcine tonsil and reported to be different in some morphological and biological points from D. congolensis. Macroscopic examination revealed multiple abscesses in the peritoneal cavities, or subcutaneous abscesses after the intraperitoneal or subcutaneous injection respectively. Histopathologic examination revealed the characteristic arrangement of the neutrophils surrounding the bacterial colony and peripheral macrophages in the abscess lesions. The lesions contained many microorganisms which showed wide range of the characteristic morphologic variation such as: mycelial elements, coccoid elements and large coccoid elements with transverse or longitudinal septa. Chlamydospore-like elements were sometimes found in the microcolonies in early lesions. The morphology of the lesions and the microorganisms was compared with those of other bacteria including D. congolensis.
mesh_terms: D000038:Abscess / Q000473:pathology*; D000192:Actinomycetales / Q000166:cytology; D000193:Actinomycetales Infections / Q000382:microbiology / Q000473:pathology*; D000818:Animals; D005337:Fibrin / Q000032:analysis; D006099:Granuloma / Q000473:pathology; D007249:Inflammation; D008100:Liver Abscess / Q000473:pathology; D008264:Macrophages / Q000473:pathology; D051379:Mice; D009336:Necrosis; D009504:Neutrophils / Q000473:pathology; D014066:Palatine Tonsil / Q000382:microbiology; D010182:Pancreatic Diseases / Q000473:pathology; D010529:Peritoneal Cavity / Q000473:pathology; D013158:Splenic Diseases / Q000473:pathology; D013552:Swine / Q000382:microbiology
chemical_list: D005337:Fibrin