Monoclonal anti-B produced by the immunization of mice with soluble salivary glycoproteins.
IgM and IgG mouse monoclonal antibodies with specificity for the blood group B determinant have been produced by immunization of mice with a partially purified salivary glycoprotein. These antibodies have been characterized and one of the IgM antibodies showed potential as a grouping reagent. The ready availability of these salivary blood group substances offers the potential to produce a wide range of related monoclonal antibodies.
D000017:ABO Blood-Group System / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D012463:Saliva / Q000276:immunology*
D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal; D006023:Glycoproteins; D007075:Immunoglobulin M