title: Pharmacokinetics as applied to total intravenous anaesthesia. Theoretical considerations.
abstract: Some theoretical considerations of pharmacokinetics as applied to total intravenous anaesthesia are discussed. The problem is the need to achieve a concentration within the therapeutic range at the receptor site. The use of linear compartment models, and of the superposition principle within these models, is discussed.
mesh_terms: D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D005045:Etomidate / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007263:Infusions, Parenteral; D007700:Kinetics; D008954:Models, Biological
chemical_list: D005045:Etomidate