Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment.
A 54-year-old man was admitted to hospital with acute rhabdomyolysis and myoglobinuria due to hypokalemia. The hypokalemia was due to chronic licorice ingestion and diuretic treatment. The myoglobinemia led to a glomerulopathy and tubulopathy. There was, however, no clinical evidence of acute renal failure (ARF). We propose that the volume expansion caused by the steroid-like actions of licorice might have prevented the development of an ARF.
D004232:Diuretics / Q000009:adverse effects*; D004576:Electromyography; D006035:Glycyrrhiza; D006801:Humans; D007008:Hypokalemia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology; D009212:Myoglobinuria / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010946:Plants, Medicinal; D011189:Potassium Chloride / Q000627:therapeutic use; D019966:Substance-Related Disorders / Q000150:complications*
D004232:Diuretics; D011189:Potassium Chloride