Morphological changes of erythrocytes in patients and carriers of Duchenne disease.
The morphology of erythrocytes was investigated in 7 patients with Duchenne dystrophy and in 6 carriers of the same disease. Upon immediate fixation, the erythrocytes showed significant stomatocytosis which was observed in a scanning electron microscope. The mean value of the % of stomatocytes was significantly different in carriers compared to healthy people (P less than 0.01).
D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008855:Microscopy, Electron, Scanning; D009136:Muscular Dystrophies / Q000097:blood*