title: [Clinical and experimental studies on muscle contracture].
abstract: Concerning muscle contracture, etiology, diagnosis and treatment still remain a problem. The author examined diagnosis and treatment clinically and examined the influence of muscle fiber after intramuscular injection of some drugs. Clinical and experimental results were as follows. 1) In the diagnosis of quadriceps muscle contracture, the measurement of buttock elevation phenomenon varies according to the examiner, and in healthy people, the same phenomenon may occur. Hence, the necessity of not over-estimating the phenomenon itself should be emphasized. 2) Adult cases with deltoid muscle contracture are accompanied by pain. 3) Intramuscular injection of chloramphenicol sol on rabbit brought remarkable muscle lesion (fibrosis, lowering of phosphorylase activity) one year after ten consecutive daily injections. Intramuscular injection of chloramphenicol sol causes irreversible lesion in the muscle and this is one of the main causes of etiology of muscle contracture.
mesh_terms: D000293:Adolescent; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003286:Contracture / Q000201:enzymology / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008297:Male; D009132:Muscles / Q000201:enzymology / Q000473:pathology*; D006005:Phosphorylases / Q000032:analysis; D011817:Rabbits
chemical_list: D006005:Phosphorylases