title: Association of centromeric heterochromatin with the nucleolus in mouse Sertoli cells.
abstract: In adult Sertoli cells of most strains of mice, all the centromeric heterochromatin is condensed in two chromocenters, one on each side of a single, large nucleolus. In a random-bred Swiss OF-1 strain, however, the nucleus has a different structural organization. Part of the heterochromatin Is seen as chromocenters in contact with the nucleolus; the rest of it is dispersed in granules of unequal size in the nucleoplasm. Such an unusual spatial arrangement of heterochromatin in interphase nucleus cannot be explained either by a difference in the nucleolar organizing regions or by a polymorphism of the C-banding of metaphase chromosomes.
mesh_terms: D000818:Animals; D002466:Cell Nucleolus / Q000032:analysis*; D002503:Centromere / Q000032:analysis*; D002875:Chromosomes / Q000032:analysis*; D006570:Heterochromatin / Q000032:analysis*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008854:Microscopy, Electron; D012708:Sertoli Cells / Q000032:analysis* / Q000648:ultrastructure
chemical_list: D006570:Heterochromatin