title: Metachromatic leukodystrophy (MLD). XV. Adult MLD with focal lesions by computed tomography.
abstract: A 31-year-old woman with adult metachromatic leukodystrophy was seen for a progressive dementia. Computed tomographic scans showed four, nearly mirror-image, hypoabsorptive areas in cerebral white matter. These symmetric bifrontal and biparietal abnormalities were accompanied by mild ventricular enlargement and by a slight to moderate volume loss throughout the brain. Diffuse white-matter abnormalities of a kind that might otherwise be anticipated in the usual childhood leukodystrophy were not seen.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000523:psychology; D014057:Tomography, X-Ray Computed