title: Regiospecific amine substitution into alpha-amanitin with retention of inhibitory properties against eukaryotic class II RNA polymerase.
mesh_terms: D000546:Amanitins / Q000138:chemical synthesis / Q000494:pharmacology; D000588:Amines; D000818:Animals; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D007455:Iodine; D009025:Morpholines; D012319:RNA Polymerase II / Q000037:antagonists & inhibitors*; D012320:RNA Polymerase III / Q000037:antagonists & inhibitors; D012617:Sea Urchins / Q000201:enzymology; D013329:Structure-Activity Relationship
chemical_list: D000546:Amanitins; D000588:Amines; D009025:Morpholines; D007455:Iodine; D012319:RNA Polymerase II; D012321:DNA-Directed RNA Polymerases; D012320:RNA Polymerase III