[Use of a BCG vaccine from a Soviet substrain for the immunotherapy of tumors caused by SA7 (C8) virus].
The oncolytic and immunotherapeutic effect of the national BCG vaccine with respect to undifferentiated sarcoma of hamster induced by the highly oncogenic adenovirus of green monkeys SA7(C8) was studied. Preliminary data on significant positive effect of the vaccine inoculated before tumor formation were obtained. A single inoculation of the vaccine into tumors did not result in tumor regression in any of the cases.
D000256:Adenoviridae / Q000472:pathogenicity*; D000261:Adenoviruses, Simian / Q000472:pathogenicity*; D000818:Animals; D000831:Animals, Newborn; D001500:BCG Vaccine / Q000627:therapeutic use*; D006224:Cricetinae; D004306:Dose-Response Relationship, Immunologic; D004353:Drug Evaluation, Preclinical; D005612:Freeze Drying; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D014586:USSR
D001500:BCG Vaccine
Ispol'zovanie vaktsiny BTsZh iz otechestvennogo subshtamma dlia immunoterapii opukholeĭ, vyzvannykh virusom SA7 (C8).