The Angelchik antireflux prosthesis. Effects on the lower esophageal sphincter of primates.
It has been shown that the ACAP causes significant increases in the LES pressure of supine primates which are maximal when properly placed at the EGJ. This effect appears to be due to posterior padding of the EGJ in supine animals and can be reproduced by dowel rods or Maloney dilators. Further studies to evaluate the contribution of this effect to the prevention of acid reflux are underway.
D000818:Animals; D004943:Esophagogastric Junction / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000503:physiopathology / Q000601:surgery*; D005769:Gastrointestinal Motility; D008253:Macaca mulatta; D010215:Papio; D011187:Posture; D011312:Pressure; D019736:Prostheses and Implants