Evaluation of creatinine phosphokinase screening as a predictor of malignant hyperthermia. A prospective study.
The efficiency, sensitivity and specificity of measurements of serum creatinine phosphokinase in the screening of malignant hyperthermia-susceptible patients in routine clinical practice has been examined. Although the overall efficiency of this screening method was high, the predictive value of a positive test in the ambulatory surgical population was poor.
D002675:Child, Preschool; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D003937:Diagnosis, Differential; D004198:Disease Susceptibility; D006801:Humans; D007527:Isoenzymes; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000517:prevention & control; D008403:Mass Screening; D011446:Prospective Studies
D007527:Isoenzymes; D003402:Creatine Kinase