Parallel increase of ascorbic acid and glutathione contents in brown adipose tissue during chronic cold exposure.
Spontaneous lipid peroxidation rate was found unchanged in the brown adipose tissue of rats chronically exposed to cold, although oxidative metabolism, ascorbic acid and poly-unsaturated phospholipid amounts increased. It is suggested that the concomitant increase in glutathione concentration may protect the tissue from a possible peroxidative process.
D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D003080:Cold Temperature / Q000009:adverse effects*; D005978:Glutathione / Q000378:metabolism*; D050356:Lipid Metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D008054:Lipid Peroxides; D005978:Glutathione; D001205:Ascorbic Acid