title: Hyperbaric exposure during pregnancy in sheep: staged and rapid decompression.
abstract: Hyperbaric exposure during pregnancy in sheep: staged and rapid decompression. Undersea Biomed Res 1983; 10(1): 11-15. --Twelve sheep with dated pregnancies were exposed for 20 min to hyperbaric pressure comparable to 165 feet of sea water weekly between the 49th and 133rd days of pregnancy. Six were decompressed in stages and six directly without decompression stops. Those that were decompressed gradually delivered normally at or near term. One lamb was abnormal, but the relationship to pressurization is unclear. Three of those decompressed rapidly aborted dead fetuses, and two others delivered mature, but affected, lambs. Under the conditions of this study staged decompression after repeated hyperbaric exposures protected the fetuses from the destructive effects of rapid decompression. Hyperbaric pressure did not alter gross anatomic development.
mesh_terms: D000027:Abortion, Incomplete / Q000209:etiology; D000034:Abortion, Veterinary / Q000209:etiology; D000818:Animals; D003664:Decompression / Q000009:adverse effects*; D005260:Female; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011312:Pressure; D012756:Sheep / Q000196:embryology / Q000502:physiology*