Clinical and laboratory evaluation of a commercial kit for measurement of serum free thyroxin ("Amerlex Free T4").
Different indexes of thyroid function were determined in conjunction with values obtained with a new commercial radioimmunoassay kit for serum free thyroxin, in 49 apparently healthy subjects, 87 pregnant women, and 142 outpatients attending the thyroid clinic. The results indicate a diagnostic success rate of 88% when free thyroxin was measured instead of estimating the so-called free thyroxin index. Furthermore, in three cases of papillary carcinoma the concentration of free thyroxin was increased, although all the other laboratory tests indicated a euthyroid state. Technically, the method is simple, rapid, and precise, and it would be of most value in the small hospital laboratory lacking the facilities of a comprehensive thyroid-function test service.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001665:Binding Sites; D002291:Carcinoma, Papillary / Q000097:blood; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011863:Radioimmunoassay; D011933:Reagent Kits, Diagnostic; D013959:Thyroid Diseases / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
D011933:Reagent Kits, Diagnostic; D013974:Thyroxine