Distribution of choline acetyltransferase and acetylcholinesterase in the nervous system of the dog.
Choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) activity were determined in 23 selected parts of the dog CNS and 4 parts of the peripheral nervous system. Maximum ChAT activity was found in the caudate nucleus and the ventral roots of the spinal cord. High activity was also present in the thalamus, the pons, the cerebral cortex, the medulla oblongata, the ventral spinal horns and the sciatic nerve. The lowest activity was measured in the cerebellum, the dorsal cord roots and the spinal ganglia. Maximum AChE activity was found in the caudate nucleus and the cerebellum. Relatively high activity was also present in the thalamus, the pons, the medulla oblongata, the grey matter of the spinal cord and the spinal ganglia. The lowest AChE activity was measured in the ventral and dorsal spinal roots.
D000110:Acetylcholinesterase / Q000032:analysis*; D000818:Animals; D001921:Brain / Q000201:enzymology; D002795:Choline O-Acetyltransferase / Q000032:analysis*; D004285:Dogs; D005260:Female; D008297:Male; D009420:Nervous System / Q000201:enzymology*; D012584:Sciatic Nerve / Q000201:enzymology; D013116:Spinal Cord / Q000201:enzymology; D014018:Tissue Distribution
D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase