title: [Biogenic monoamines and their precursors in rats with spontaneous arterial hypertension].
abstract: Content of tryptophane, tyrosine, serotonin, noradrenaline, adrenaline and dopamine was studied in blood serum and various brain regions of rats with genetically determined spontaneous form of hypertension. The arterial pressure of these animals was shown to depend on activity of noradrenaline-, serotonin- and dopaminergic systems of brain. Oppositely directed alterations in content of dopamine and noradrenaline were observed in various brain regions apparently as a result of changes in activity of the enzymes involved in the amines synthesis and degradation.
mesh_terms: D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D006973:Hypertension / Q000235:genetics / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D014364:Tryptophan / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism
chemical_list: D001679:Biogenic Amines; D012701:Serotonin; D014443:Tyrosine; D014364:Tryptophan; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Biogennye monoaminy i ikh predshestvenniki u krys so spontannoĭ arterial'noĭ gipertenzieĭ.