title: [Pulmonary arterial hypertension and generalized scleroderma. A propos of 10 cases].
abstract: Whereas pulmonary fibrosis is a very frequent manifestation of scleroderma, pulmonary hypertension of the precapillary type is a much rarer occurrence in this affection. Two cases of scleroderma with subsequent development of a pulmonary hypertension are reported. Various hypotheses have been advanced to explain the origin of this disorder during the course of scleroderma. Rather than a direct consequence of the sclerodermic pulmonary fibrosis it probably arises secondary to the specific, diffuse, primary pulmonary vascular lesions.
mesh_terms: D000368:Aged; D001158:Arteries / Q000473:pathology; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000473:pathology; D006984:Hypertrophy; D008168:Lung / Q000098:blood supply; D008875:Middle Aged; D011652:Pulmonary Circulation; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology; D014661:Vasoconstriction
vernacular_title: Hypertension artérielle pulmonaire et sclérodermie généralisée. A propos de deux cas.