title: Subcellular distribution and binding of heavy metals in the untreated liver of the squid; comparison with data from the livers of cadmium and silver-exposed rats.
abstract: In natural squid liver, about 30% of the total Cd present was found in the cytosolic fraction. A large portion of this Cd was bound to high molecular weight species (mol. wt greater than 70,000). In contrast to Cd, about 60% of the total Ag occurred in the cytosolic fraction; Ag was bound mainly to low molecular weight species (mol. wt less than 20,000).
mesh_terms: D000818:Animals; D001665:Binding Sites; D002104:Cadmium / Q000378:metabolism*; D002850:Chromatography, Gel; D049832:Decapodiformes / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains / Q000378:metabolism*; D012834:Silver / Q000378:metabolism*; D013347:Subcellular Fractions / Q000378:metabolism
chemical_list: D002104:Cadmium; D012834:Silver