Inheritance of congenital cataracts and microphthalmia in the Miniature Schnauzer.
Congenital cataracts and microphthalmia in the Miniature Schnauzer were inherited as an autosomal recessive trait. Eighteen matings of affected X affected Miniature Schnauzers resulted in 87 offspring with congenital cataracts and microphthalmia (49 males/38 females). Two matings of congenital cataractous and microphthalmic Miniature Schnauzers (2 females) X a normal Miniature Schnauzer (1 male) yielded 11 clinically normal Miniature Schnauzers (7 males/4 females). Eighteen matings of congenital cataractous and microphthalmic Miniature Schnauzers (6 males) X carrier Miniature Schnauzers (9 females) produced 81 offspring; 39 exhibited congenital cataracts and microphthalmia (20 males/19 females) and 42 had clinically normal eyes (17 males/25 females).
D000818:Animals; D002386:Cataract / Q000235:genetics / Q000662:veterinary*; D004283:Dog Diseases / Q000151:congenital* / Q000235:genetics; D004285:Dogs; D005260:Female; D008297:Male; D008850:Microphthalmos / Q000235:genetics / Q000662:veterinary*; D011247:Pregnancy