Quantitative structure-activity study on the mechanism of inhibition of microsomal p-hydroxylation of aniline by alcohols. Role of steric factors.
D000438:Alcohols / Q000494:pharmacology*; D000814:Aniline Compounds / Q000378:metabolism*; D000815:Aniline Hydroxylase / Q000037:antagonists & inhibitors*; D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors*; D001665:Binding Sites; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology*; D008956:Models, Chemical; D011817:Rabbits; D013329:Structure-Activity Relationship
D000438:Alcohols; D000814:Aniline Compounds; D003577:Cytochrome P-450 Enzyme System; D000815:Aniline Hydroxylase; D001189:Aryl Hydrocarbon Hydroxylases; C023650:aniline