Inappropriate ADH secretion in tetanus.
Of 99 patients with adult tetanus, 7 developed the clinical and biochemical features of the syndrome of inappropriate antidiuretic hormone secretion (SIADH). The diagnosis for these 7 patients was severe tetanus (dysphagia with frequent severe spasms); 5/7 patients had evidence of autonomic overactivity (tachycardia, sweating, cardiovascular lability, and hypersalivation). They all responded favorably to fluid restriction, SIADH was self-limited and resolved as the disease regressed.
D000328:Adult; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013742:Tetanus / Q000150:complications* / Q000175:diagnosis