Quantitative SEM-analysis of adhesive and thrombogenic properties of vascular prostheses.
The perfusion technique to measure the relative adhesive and thrombogenic indices of vascular prostheses by a quantitative scanning electron microscopy has been described. To normalize the experiments with different samples of plasma we compared the adhesive and thrombogenic properties of the analyzed prostheses with those of normal and denuded human umbilical vein. The results indicate that adhesive and thrombogenic indices of Dardik, Bakulev and Gore-Tex grafts approximate to those of the non-damaged umbilical vein, while the same indices of Solcograft-P prostheses are considerably higher. The method may be useful for standardizing the properties of new prostheses and bioimplants for cardiovascular surgery.
D001705:Bioprosthesis; D001792:Blood Platelets / Q000648:ultrastructure*; D001807:Blood Vessel Prosthesis; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010973:Platelet Adhesiveness; D010976:Platelet Count; D014471:Umbilical Veins / Q000648:ultrastructure