Action of angiotensin II on cultured brain stem neurons of the rat.
Following the application of angiotensin II to cultured lower brain stem neurons of rat embryos, the facilitatory response was mostly seen in small-sized oval, fusiform, and polygonal neurons, while the inhibitory response was seen in medium-sized pyramidal and multipolar neurons. Saralasin blocked both facilitatory and slow inhibitory responses, but had no effect on the fast inhibitory response.
D000200:Action Potentials / Q000187:drug effects; D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D001933:Brain Stem / Q000166:cytology / Q000187:drug effects*; D046508:Culture Techniques; D009474:Neurons / Q000166:cytology / Q000187:drug effects*; D051381:Rats; D012504:Saralasin / Q000494:pharmacology
D000804:Angiotensin II; D012504:Saralasin