title: Blood dyscrasias and mianserin.
abstract: Four cases are described in which the drug mianserin was implicated in the development of leucopenia. In one case this was accompanied by fatal aplastic anaemia. In a second, generalized bone marrow depression occurred, although leucopenia was the only clinically significant manifestation. Mianserin may depress bone marrow function and haematological surveillance is appropriate for patients taking this drug.
mesh_terms: D000328:Adult; D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000741:Anemia, Aplastic / Q000139:chemically induced*; D003984:Dibenzazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008803:Mianserin / Q000009:adverse effects*; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced*
chemical_list: D003984:Dibenzazepines; D008803:Mianserin