title: Erythema marginatum in rheumatic fever: early diagnosis by skin biopsy.
abstract: Skin biopsy of a 10-year-old boy with a 3-week history of recurrent rash and fever demonstrated histologic changes suggesting a diagnosis of erythema marginatum associated with rheumatic fever. Subsequently, the patient developed classic cardiac and arthritic manifestations. Skin biopsy is recommended for the early diagnosis of rheumatic fever.
mesh_terms: D001706:Biopsy; D002648:Child; D004890:Erythema / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D012213:Rheumatic Fever / Q000150:complications*; D012867:Skin / Q000473:pathology*