Anaphylaxis caused by anti-cremophor EL IgG STS antibodies in a case of reaction to althesin.
The action of cremophor EL, the solubilizing agent of Althesin in a case of anaphylactic reaction which occurred during the induction of anaesthesia has been demonstrated using the Prausnitz-Küstner (P-K) test 10 weeks later. This test was positive at 2 h, with the heated serum and cremophor, proving the presence of allergic IgG STS antibodies.
D000293:Adolescent; D000530:Alfaxalone Alfadolone Mixture / Q000009:adverse effects*; D000707:Anaphylaxis / Q000139:chemically induced*; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D005260:Female; D005990:Glycerol / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007431:Intraoperative Complications / Q000209:etiology; D012997:Solvents / Q000009:adverse effects*
D007074:Immunoglobulin G; D012997:Solvents; C000515:cremophor EL; D000530:Alfaxalone Alfadolone Mixture; D005990:Glycerol