title: Local and systemic effects of pindolol eye drops.
abstract: Local (reduction of intraocular pressure) and systemic (inhibition of exercise-induced tachycardia) effects of 1% and 0.25% pindolol eye drops have been studied in a balanced cross-over double-blind trial in 12 healthy volunteers. Both concentrations produced a comparable reduction in intraocular pressure while the inhibition of exercise tachycardia was significantly less with the lower concentration.
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D009883:Ophthalmic Solutions; D005082:Physical Exertion; D010869:Pindolol / Q000008:administration & dosage* / Q000494:pharmacology
chemical_list: D009883:Ophthalmic Solutions; D010869:Pindolol