title: Experience with etomidate as part of a total intravenous anaesthetic technique.
abstract: Etomidate and fentanyl have been used in three different ways as part of a total intravenous anaesthetic technique. The results suggest that etomidate and fentanyl should be infused separately. The quality of induction of anaesthesia following a rapid infusion of etomidate was comparable with that following a bolus injection of thiopentone. None of the techniques had a significantly deleterious effect on the cardiovascular system and, where measured, on respiratory, renal or hepatic function.
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D000771:Anesthesia, Intravenous / Q000379:methods*; D005045:Etomidate / Q000008:administration & dosage / Q000494:pharmacology; D005240:Feasibility Studies; D005260:Female; D005283:Fentanyl; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage; D007263:Infusions, Parenteral; D008111:Liver Function Tests; D010865:Pilot Projects; D012119:Respiration / Q000187:drug effects; D013997:Time Factors
chemical_list: D007093:Imidazoles; D005283:Fentanyl; D005045:Etomidate