title: Studies on the pathogenesis of staphylococcal osteomyelitis in chickens. II. Role of the respiratory tract as a route of infection.
abstract: Groups of 6-week-old broiler chickens were exposed to Staphylococcus aureus by aerosol, intratracheal or intravenous (control) inoculation. No lesions were produced by aerosol. A single dose of up to 5 X 10(10) organisms given intratracheally failed to produce any lesions. Single or repeated doses of 5 X 10(11) organisms given intratracheally resulted in osteomyelitis in a low proportion of chickens.
mesh_terms: D000336:Aerosols; D000391:Air Microbiology; D000818:Animals; D002645:Chickens; D005260:Female; D008297:Male; D010019:Osteomyelitis / Q000635:transmission / Q000662:veterinary*; D011201:Poultry Diseases / Q000635:transmission*; D012137:Respiratory System / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000635:transmission / Q000662:veterinary*; D014132:Trachea / Q000382:microbiology
chemical_list: D000336:Aerosols