title: Interstitial radiotherapy for localized carcinoma of the prostate.
abstract: Forty-two patients with localized carcinoma of the prostate have been treated with interstitial implantation of iodine 125 seeds after a thorough staging process. The procedure was well tolerated and carried acceptable morbidity and no mortality. Of major concern, however, was the failure of local control of the tumour in a high proportion (88%) of patients at 1 year. Combined interstitial and external beam radiotherapy may overcome this.
mesh_terms: D000368:Aged; D001918:Brachytherapy; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000532:radiotherapy*
chemical_list: D007457:Iodine Radioisotopes