Chloride:phosphate ratio with hypercalcemia secondary to thiazide administration.
The chloride:phosphate ratio is of only limited value in aiding the clinician in the differential diagnosis of hypercalcemia. The use of thiazide diuretics may cause hypercalcemia with a chloride:phosphate ratio said to be consistent with a diagnosis of primary hyperparathyroidism. Parathormone assay remains the "gold standard" for definitive diagnosis of hyperparathyroidism.
D000368:Aged; D001581:Benzothiadiazines; D002712:Chlorides / Q000097:blood*; D003951:Diagnostic Errors; D004232:Diuretics; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000175:diagnosis; D006961:Hyperparathyroidism / Q000175:diagnosis; D010710:Phosphates / Q000097:blood*; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects; D014223:Triamterene / Q000009:adverse effects*
D001581:Benzothiadiazines; D002712:Chlorides; D004232:Diuretics; D010710:Phosphates; D049993:Sodium Chloride Symporter Inhibitors; D014223:Triamterene