title: The detachment, attachment and growth capacity of human glioma and glia cells in culture.
abstract: The detachment, attachment and growth were studied in malignant glioma and normal glia cells in culture, using the palladium-agarose cloning method. The number of cells in each individual clone was repeatedly counted throughout 10 days. All four glioma cell-lines studied detached and attached themselves at higher rates than the normal, diploid, glia cells. This dynamic behaviour seemed to be a general property of cultured, malignant, glioma cells. All the cell-lines contained clones with different properties. Some clones were growing, others were nearly constant in cell number and yet others decreased in cell number as a function of time. The differences between these types of clones were surprisingly sharp.
mesh_terms: D002448:Cell Adhesion; D002455:Cell Division; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002478:Cells, Cultured; D005910:Glioma / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007700:Kinetics; D009457:Neuroglia / Q000166:cytology / Q000502:physiology*