Single-day drug treatment of amebic liver abscess.
This double-blind trial was initiated to test, in a controlled study, the value of single-day drug treatment of amebic liver abscess. Patients were treated with 2 g either of ornidazole or tinidazole, two newly developed 5-nitroimidazole derivatives, given in two equal doses during the course of 1 day. A success rate of over 94% in the 72 patients from both treatment groups who were followed up for 6 months demonstrates the efficacy of the single-day drug treatment.
D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008101:Liver Abscess, Amebic / Q000188:drug therapy*; D008297:Male; D009593:Nitroimidazoles / Q000008:administration & dosage*; D009950:Ornidazole / Q000008:administration & dosage*; D014011:Tinidazole / Q000008:administration & dosage*
D009593:Nitroimidazoles; D014011:Tinidazole; D009950:Ornidazole