New antibiotic, isohematinic acid. II. Physico-chemical properties, structural elucidation and biological activities.
Physico-chemical characterization of isohematinic acid revealed that this antibiotic has a succinimide nucleus. From elemental analysis, the molecular formula of isohematinic acid was determined to be C8H9NO4. Isohematinic acid showed weak antimicrobial activities against anaerobic bacteria, such as Bacteroides fragilis and Propionibacterium acnes.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D051379:Mice; D013388:Succinimides / Q000302:isolation & purification / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013388:Succinimides; C038713:isohematinic acid