title: Trichosporon cutaneum endocarditis: a sequela of intravenous drug abuse.
abstract: A 42-year-old abuser of intravenous drugs developed fulminant aortic insufficiency necessitating a prosthetic valve replacement. Trichosporon cutaneum was isolated from the surgical specimen. The patient received a total of 3,195 g of amphotericin B, and 148 g of 5-fluorocytosine during his four-month hospitalization. He manifested no additional signs of persistent fungal infection, but died one year later from an intracerebral hemorrhage.
mesh_terms: D000328:Adult; D004696:Endocarditis / Q000209:etiology*; D003932:Heroin / Q000008:administration & dosage; D006556:Heroin Dependence / Q000150:complications; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D003904:Mitosporic Fungi; D009181:Mycoses; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D003932:Heroin