[Detection of toxoplasmosis by agglutination of parasites. Value of a very sensitive antigen in the search for specific immunoglobulins G].
A method that increases the sensitivity and specificity of the direct agglutination (AG) test for diagnosis of infection with Toxoplasma gondii is described. Qualitative results in the Sabin-Feldman dye test (DT) and AG test were in excellent agreement (98%). Differences in titers between these two tests often related to the length of time the individual was infected. The AG titer is most often lower than the DT titer during acute (recent) infection; the AG test titer is most often higher than the DT titer in older or chronic infection. If the AG test antigen described here can be made available, the AG test would be ideal for use as a screening test and would provide a simple and inexpensive means for the surveillance of seronegative women during pregnancy and for detection of seroconversions.
D000372:Agglutination Tests; D000918:Antibody Specificity; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000276:immunology; D014125:Toxoplasmosis, Congenital / Q000517:prevention & control
D007074:Immunoglobulin G
Dépistage de la toxoplasmose par agglutination des parasites. Intérêt d'un antigène très sensible pour la recherche des immunoglobulines G spécifiques.