The presence of a substance in the pancreas that inhibits mitochondrial respiration.
Evidence is presented which indicates that there is present in the pancreatic tissue of rats a substance, possibly some type of protein or a related substance, which inhibits mitochondrial respiration. The inhibitory substance may be associated or bound to cell membrane and is released on homogenization of the tissue. This substance may play a significant role in pancreatitis and shock.
D000818:Animals; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D010101:Oxygen Consumption; D010179:Pancreas / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains