[Changes in ocular tonus, pH and concentration of ascorbic acid and lactic acid in the aqueous humor of rabbits treated with epinephrine].
The authors state the results of their research on the modification of the aqueous humor caused by the instillation of the Epinephrine in a group of ten rabbits. The results of these studies illustrate the variations of pH, the ocular tone, the concentration of lactic and ascorbic acid. In all the rabbits examined Epinephrine was instillated in the RE while in the LE distilled water was instillated for the control. For two hours from the beginning of the experiment, every 10 minutes measurements of the ocular tone in both eyes were taken. At the end of the two hours a sample of aqueous humor was taken from the RE and LE; It was found that: 1) The drugs produced a vary quick and prolonged decrease of the ocular tone. 2) There are no significant variations in the pH or in the concentration of lactic acid. 3) There was a notable reduction of the concentration of ascorbic acid.
D000818:Animals; D001082:Aqueous Humor / Q000032:analysis / Q000187:drug effects; D001205:Ascorbic Acid / Q000032:analysis; D004837:Epinephrine / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007429:Intraocular Pressure / Q000187:drug effects*; D007773:Lactates / Q000032:analysis; D011817:Rabbits; D014065:Tonometry, Ocular
D007773:Lactates; D001205:Ascorbic Acid; D004837:Epinephrine
Modificazione del tono oculare, del pH, della concentrazione di acido ascorbico e di acido lattico nell'umore acqueo di coniglio trattato con epinefrina.