[Dry weight of isolated normal human hepatocytes and in chronic hepatitis].
Dry weight of hepatocytes of 44 patients both normal and suffering from chronic hepatitis was measured interferometrically. The hepatocyte dry weight of the normal liver was about 431 pg. With the progression of the disease, this weight increased up to 640 pg. The dry weight concentration in this case did not change. The dry weight of hepatocytes increases proportionally to the polyploidy degree both in the norm and at chronic hepatitis. It was shown that cell hypertrophy not associated with cell proliferation and polyploidy is of great importance for the reparative liver growth. In patients with strong liver disease, it was increased by 30% in comparison with the normal condition.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D006519:Hepatitis, Alcoholic / Q000473:pathology*; D006525:Hepatitis, Viral, Human / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000166:cytology*; D008875:Middle Aged; D009929:Organ Size; D011003:Ploidies; D012016:Reference Values
Sukhoĭ ves izolirovannykh gepatotsitov cheloveka v norme i pri khronicheskom gepatite.