[Subpartal tocolysis in fetal distress situations].
43 patients in 31-42 weeks of gestation showed fetal distress confirmed by fetal scalp blood measurements and/or cardiotocography. In addition to conventional treatment of intrapartum fetal distress a beta-adrenergic receptor stimulator, fenoterol was given, 1. as iv. bolus of 25 micrograms in two min. 2. iv. bolus of 25 micrograms + iv. infusion of 3-4 micrograms/min or 3. iv. infusion of 3-4 micrograms/min. The suppression of labor was sufficient in 88 per cent and the improvement of fetal condition allowed the avoidance of an emergency operation in 84 per cent. The diagnosis was confirmed in addition to CTG, by fetal scalp blood pH measurements in 65 per cent of cases. The fetal blood pH was 7,20 and BE - 8,77 before therapy, after tocolytic therapy pH 7,23 and BE - 7,53 and in umbilical cord arterial blood pH 7,21 and BE - 12,12. Apgar scores at 1' and 5' averaged 8,0 and 9,1.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use*; D005316:Fetal Distress / Q000188:drug therapy*; D005311:Fetal Hypoxia / Q000188:drug therapy; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007263:Infusions, Parenteral; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D014590:Uterine Contraction / Q000187:drug effects
D004983:Ethanolamines; D005280:Fenoterol; D010100:Oxygen
Subpartale Tokolyse bei fetalen Notsituationen.