Analgesic activity of certain tripeptide-beta-phenethylamide analogs.
Studies of the analgesic effect of tripeptide-beta-phenethylamides are described, and their structure-activity relationship is discussed. SD-25, which has a methyl group at R2, and a hydroxymethyl group at R3 of beta-phenethylamide, was the most potent one of the 8 analogs tested.
D000698:Analgesia; D000818:Animals; D008297:Male; D051379:Mice; D009842:Oligopeptides / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D009842:Oligopeptides