A new radiopharmaceutical: 99mTc DMP for renal scanning.
99mTc-Dimercaptopropionic acid (DMP), a new renal scanning agent was synthesized, and the optimum preparative conditions and stability of this compound were determined. It was demonstrated that scans performed with this agent in rats showed highly selective renal images which may be of promise in future clinical use. The relationships between chemical structure and renal affinity are discussed based on the present results.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D007668:Kidney / Q000000981:diagnostic imaging*; D008297:Male; D015609:Organotechnetium Compounds; D011817:Rabbits; D011877:Radionuclide Imaging; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013667:Technetium / Q000378:metabolism; D014018:Tissue Distribution
D015609:Organotechnetium Compounds; D013438:Sulfhydryl Compounds; C038842:technetium Tc 99m 2,3-dimercaptopropionic acid; D013667:Technetium