Rheological studies on calcium-sensitive gelation of actin filaments by actinogelin.
Actinogelin, a regulatory protein of cell motility, enhanced gelation of actin filaments in the absence of calcium ions, only on standing still or with very low velocity gradients ( less than 0.1 s-1). The Ca2+-sensitive action of actinogelin on action filaments was dependent on a weak external force. In the presence of a micromolar level of Ca2+, actinogelin did not affect the network formation of actin filaments at all.
D000199:Actins; D000818:Animals; D001718:Birefringence; D002118:Calcium; D002286:Carcinoma, Ehrlich Tumor; D002465:Cell Movement; D005782:Gels; D051379:Mice; D008840:Microfilament Proteins; D009132:Muscles; D009363:Neoplasm Proteins; D011817:Rabbits; D014783:Viscosity
D000199:Actins; D005782:Gels; D008840:Microfilament Proteins; D009363:Neoplasm Proteins; C029354:actinogelin; D002118:Calcium