Bronchoconstriction caused by Florida red tide toxins.
T17, a toxin purified from laboratory cultures of Florida's redtide organism, Ptychodiscus brevis (formerly Gymnodinium breve), produces bronchoconstriction in anesthetized artificially-ventilated guinea pigs. Bronchoconstriction, measured as a resistance to mechanical pulmonary inflation, was antagonized by atropine, but not by interruption of vagal nerve stimulation or diaphragm dissection.
D000818:Animals; D001980:Bronchi / Q000187:drug effects*; D004141:Dinoflagellida / Q000472:pathogenicity*; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D008387:Marine Toxins / Q000633:toxicity*; D009469:Neuromuscular Junction / Q000187:drug effects
D008387:Marine Toxins