Maternal hypertension during pregnancy and high blood pressure in children. Preliminary communication.
A group of 29 women with previous pre-eclampsia/hypertension in pregnancy and 37 of their children were investigated. At follow-up 7-12 years later, all mothers had mild to moderate hypertension. The children had a significantly higher blood pressure than age and sex-matched controls. Intracellular Na+ in erythrocytes from the children was normal but potassium was significantly higher compared to normotensive controls. The history of maternal essential hypertension and previous pre-eclampsia/hypertension in pregnancy seems to indicate an increased risk for high blood pressure in children, evident before puberty.
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D002648:Child; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D008297:Male; D011188:Potassium / Q000097:blood; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000235:genetics* / Q000503:physiopathology; D011627:Puberty; D012964:Sodium / Q000097:blood
D012964:Sodium; D011188:Potassium