title: [Compounds with potential antitumor activity. II. N,N'-(1-Diadamantandicarboxyamides)].
abstract: Some alkanic aromatic diamines were acylated at the amino groups with 1-adamantane carboxylic acid chloride. The resulting compounds were then tested for their action, in vivo in lymphocytic murine leukemia P 388. These derivatives, submitted to a preliminary test, did not show significant antileukemic activity.
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice
chemical_list: D000970:Antineoplastic Agents; D000218:Adamantane
vernacular_title: Composti a presunta attività antitumorale. Nota II. N,N'-(1-Diadamantandicarbossiamidi).