The cutting-edge microvascular needle. A scanning electron microscopic study.
The authors have compared the vascular endothelial damage caused by blunt-tipped microvascular needles as reported previously with that of sharp cutting-edged needles of comparable size. The same four distinct vascular lesions were found with cutting-edged needles as with the blunt-tipped needles. Even though one experimenter made all of the lesions, and all of the tissue was handled in the same fashion, there was much variation in the extent of the intimal damage. Overall, cutting-edged needles produced slightly less intimal tearing and platelet aggregation than blunt-tipped needles, but the difference was not striking.
D000818:Animals; D008833:Microcirculation; D008855:Microscopy, Electron, Scanning; D008866:Microsurgery / Q000295:instrumentation*; D009339:Needles; D051381:Rats; D011919:Rats, Inbred Strains