A retrospective analysis of drug therapy in patients with rheumatoid arthritis.
A retrospective analysis of the pharmacotherapy used in 100 patients during their illness was performed. The method was that of a standardized interview based on a questionnaire. Analysis of the data showed that salicylates still dominate among the first-line antirheumatic drugs, but are gradually being replaced by newer antirheumatic agents. A large number of patients received drugs belonging to the group of pyrazolidine compounds. Basic therapy primarily consisted of chrysotherapy; therapy with antimalarials had to be discontinued due to side effects in a high percentage of cases. An interesting finding is the high number of patients treated in the long term with glucocorticoids with apparently good tolerance.
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000962:Antimalarials / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006046:Gold / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010396:Penicillamine / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D000962:Antimalarials; D005938:Glucocorticoids; D006046:Gold; D010396:Penicillamine