Plasmacytomas in rhesus monkeys.
Plasmacytomas were found in two adult male rhesus monkeys. Involvement of vertebral bone marrow, skin, kidney, and soft tissues was present in one case and infiltration of the stomach, lymph nodes, and retroperitoneum in the other. Both tumors were seen to be typical plasmacytomas by light and electron microscopy. Strong IgA immunoreactivity was demonstrated in the tumor cells of one case and weak reactivity in the other using rabbit anti-human immunoglobulin sera and the immunoperoxidase technique. Also, IgA was demonstrated in tumor extracts and in the serum of one case.
D000818:Animals; D006651:Histocytochemistry; D007070:Immunoglobulin A / Q000032:analysis; D008253:Macaca mulatta / Q000276:immunology; D008297:Male; D008992:Monkey Diseases / Q000276:immunology / Q000473:pathology*; D009362:Neoplasm Metastasis; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology / Q000662:veterinary*
D007070:Immunoglobulin A