title: [Malignant adrenal cortex tumors responsible for primary hyperaldosteronism and biological hypercorticism. Remarks apropos of 2 surgically-treated cases].
abstract: Two cases of malignant adrenal cortex tumors revealed by primary hyperaldosteronism with hypertension, and associated with a biological hypercortisonism, are reported. Diagnosis of this very rare affection depends on the finding of marked biological hyperaldosteronism associated with a large adrenal tumor. The outcome appears to be rapidly fatal for tumors exceeding 5 cm in diameter and associated with lymph node invasion. This raises the problem of the utility of surgery in these cases, operative intervention apparently accelerating progression of the lesion. In practice, however, a laparotomy is always justifiable, the most rational biopsy being excision of the tumor.
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000601:surgery; D000308:Adrenocortical Hyperfunction / Q000097:blood / Q000209:etiology*; D000328:Adult; D002277:Carcinoma / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology*; D006973:Hypertension / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis
vernacular_title: Corticosurrénalomes malins responsables d'un hyperaldostéronisme primaire et d'un hypercorticisme biologique. Réflexions à propos de 2 cas opérés.