The pathogenetic significance of congophilic angiopathy.
Congophilic angiopathy has been separated into two forms. A primary vasculopathy is described in which amyloid deposition is the initial morphological brain change and is of pathogenetic importance in the development of dementia or brain hemorrhage. Another form occurs in Alzheimer's disease and is incidental to the brain damage resulting from senile plaques.
D000686:Amyloidosis / Q000473:pathology*; D000818:Animals; D001927:Brain Diseases / Q000235:genetics / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000209:etiology; D002560:Cerebrovascular Circulation; D003704:Dementia / Q000209:etiology; D003711:Demyelinating Diseases / Q000473:pathology*; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains