Amino acid sequence of the rabies virus glycoprotein deduced from its cloned gene.
Double-stranded complementary DNA was synthesized from rabies virus-specific glycoprotein mRNA and inserted into the Pst I site of pBR322. The glycoprotein inserted sequence contains approximately 1.75 kilobase pairs and lacks only approximately 35 nucleotides from the 5' terminus of the glycoprotein mRNA. The nucleotide sequence indicates a polypeptide of 524 amino acids beginning with an initiation codon ATG and ending with a termination of codon TGA. The first 19 amino acids make up a signal peptide preceding the sequence lys-phe-pro-ile-tyr-thr- which has been identified by the N-terminal analysis of amino acids of the purified rabies virus glycoprotein.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D006224:Cricetinae; D004247:DNA / Q000302:isolation & purification; D005796:Genes; D005814:Genes, Viral; D006023:Glycoproteins / Q000235:genetics*; D007668:Kidney; D010957:Plasmids; D012333:RNA, Messenger / Q000235:genetics; D014764:Viral Proteins / Q000235:genetics*
D006023:Glycoproteins; D012333:RNA, Messenger; D014764:Viral Proteins; D004247:DNA