title: [Effect of oxygen on the growth, respiratory rate and morphology of Candida utilis cells in periodic and continuous cultures].
abstract: The aim of this work was to study how the concentration of oxygen dissolved in the cultural broth influenced the respiration and morphology of the yeast Candida utilis in batch and continuous cultures. Highly effective respiration was registered in cells growing for a certain period of time at low oxygen concentrations limiting the growth; the respiration was characterized by low values of the Michaelis constant kc and the critical concentration of dissolved oxygen Ccr. When passing from the low oxygen concentration to a high one, the character of cellular respiration changed abruptly in the cells whose growth was limited with oxygen for a long time. The morphology of the culture limited with oxygen was characterized by an increase in the percentage of elongated forms in the population. The respiration of the cells cultivated at high oxygen concentrations, when their growth was either non-limited or limited by glucose, was distinguished by high Ccr values and slow respiration rates at small oxygen concentrations while the dependence of the respiration rate on the concentration of oxygen had an about S-shaped character.
mesh_terms: D002175:Candida / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007700:Kinetics; D010100:Oxygen / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D010100:Oxygen
vernacular_title: O vliianii kisloroda na rost, skorost' dykhaniia i morfologiiu kletok Candida utilis v periodicheskikh i nepreryvnykh kul'turakh.