Proteins of guinea-pig bile: selective resorption in the gall bladder.
We have examined and compared the proteins present in guinea-pig bile as collected either from the common hepatic duct or from the gall bladder. Guinea-pig bile, collected from the common bile duct, has a rather low concentration of protein. Detailed examination shows that the concentrations of actively transported proteins such as immunoglobulin A and haptoglobin:haemoglobin complexes are markedly lower than in rats although the concentrations of proteins which, like albumin, leak non-specifically into bile are similar in the two species. We also find that the protein composition of guinea-pig bile is extensively and selectively modified by resorption of protein in the gall bladder.
D000818:Animals; D001646:Bile / Q000032:analysis* / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D005704:Gallbladder / Q000378:metabolism*; D006168:Guinea Pigs; D007123:Immunoelectrophoresis, Two-Dimensional; D008099:Liver / Q000378:metabolism; D011506:Proteins / Q000032:analysis*
D011506:Proteins