[The effect of immobilizing stress on the ultrastructure of the myocardium in rats in different age groups].
The effect of stress from 120 minute - immobilization on myocardium ultrastructure was studied in rats of different age (4, 14, and 26 months) groups. Immobilizing stress caused various ultrastructural changes by adaptation and degeneration in many myocardial cells. The most frequent among them were mitochondrial swelling, widening of sarcoplasmic reticulum and increased nuclear lobation; degenerative changes were especially cytolytic foci and multiplied lipid dorplets. Factor of age was very important. Outstanding adaptation changes (mitochondrial swelling, reticulum dilation) occurred in young rats and was usually reversible, the least conspicuous changes were in adult rats at the age of 14 months, the most conspicuous early degenerative changes were found in old rats at the age of 26 months. The causal mechanisms of changes were discussed mainly by comparing morphological and biochemical findings.
D000818:Animals; D007103:Immobilization; D008297:Male; D009206:Myocardium / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000209:etiology / Q000473:pathology*
Vplyv imobilizacného stresu na ultrastruktúru myokardu potkanov rôznych vekových skupin.