[Fatty-acid composition of lipids and physicochemical characteristics of membrane fractions and the membrane of endoplasmic reticulum of thymus and Pliss' lymphosarcoma].
The paper is concerned with composition of neutral lipids and phospholipids, the regularity of lipid bilayer and structural reorganization of plasma membranes, and membranes of smooth and rough cell reticulum of thymus and Pliss lymphosarcoma are studied at linear and stationary growth phase. No qualitative differences are found in the fatty-acid composition of lipid membranes in normal and tumour cells. In plasma membranes of phospholipids and in membranes of smooth reticulum of tumour cells the unsaturated lipid component increases in the process of growth, the cholesterin/phospholipids ratio decreases, fluidity of the lipid bilayer diminishes and structural heterogeneity of these membranes rises while in membranes of rough reticulum the saturation of lipids increases, but the cholesterin/phospholipids ratio does not change. The temperatures of structural reorganization also does not change, which evidences for a less structural lability of membranes of rough reticulum as compared with other membranes.
D000818:Animals; D002784:Cholesterol / Q000032:analysis; D004721:Endoplasmic Reticulum / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D008051:Lipid Bilayers; D008055:Lipids / Q000032:analysis*; D008228:Lymphoma, Non-Hodgkin / Q000032:analysis*; D008297:Male; D008560:Membrane Fluidity; D008563:Membrane Lipids / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis; D051381:Rats; D012513:Sarcoma, Experimental / Q000032:analysis; D013950:Thymus Gland / Q000032:analysis*
D005227:Fatty Acids; D008051:Lipid Bilayers; D008055:Lipids; D008563:Membrane Lipids; D010743:Phospholipids; D002784:Cholesterol
Zhirnokislotnyĭ sostav lipidov i fiziko-rhimicheskie kharakteristiki membrannykh fraktsiĭ timusa i limfosarkomy Plissa.