The cerebrum of Dugesia gonocephala s.1. Platyhelminthes, Turbellaria, Tricladida. Morphological and functional observations.
Investigation of the cerebrum of Dugesia gonocephala s.1. using modern techniques has shown that the neurons of these animals situated at the bottom of the phylogenetic scale are basically the same as those of Vertebrates from the ultrastructural and molecular standpoints (tetanus toxin binding). There is no evidence of any biochemical glio-neuronal relationship, nor do the so-called supporting cells appear similar to the glial cells of the higher Vertebrates from this point of view.
D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D005904:Glial Fibrillary Acidic Protein; D007381:Intermediate Filament Proteins / Q000378:metabolism; D008565:Membrane Proteins; D008854:Microscopy, Electron; D010932:Planarians / Q000033:anatomy & histology*; D011950:Receptors, Cholinergic / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D013744:Tetanus Toxin / Q000378:metabolism; D014419:Turbellaria / Q000033:anatomy & histology*
D005904:Glial Fibrillary Acidic Protein; D007381:Intermediate Filament Proteins; D008565:Membrane Proteins; D011950:Receptors, Cholinergic; D009418:S100 Proteins; D013744:Tetanus Toxin; C028728:tetanus toxin receptor