Primary acquired hypogammaglobulinaemia complicated by antibody-mediated haemolysis and pernicious anaemia. A case report.
A case of primary acquired hypogammaglobulinaemia complicated by the unusual combination of antibody-mediated haemolysis and pernicious anaemia is described. The natural history, laboratory results and treatment are discussed. An initial partial response to steroids was followed by relapse. Immunosuppression and plasmapheresis failed to affect the haemolysis.
D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications* / Q000276:immunology; D000752:Anemia, Pernicious / Q000150:complications* / Q000276:immunology; D001323:Autoantibodies / Q000276:immunology*; D001327:Autoimmune Diseases / Q000150:complications; D005260:Female; D006461:Hemolysis; D006801:Humans
D001323:Autoantibodies