title: Superior oblique myokymia.
abstract: Superior oblique myokymia is an unusual eye movement phenomenon generally considered to be a uniocular rotary microtremor easily treated with carbamazepine. Eleven new cases are presented, one with a unique combination of motility problems, emphasizing that the disorder may have varying clinical manifestations. Long-term follow-up of the patients revealed a natural history of recurrent spontaneous remissions and relapses. Treatment with carbamazepine was of short-term benefit in most patients but failed to affect the long-term course of the disease. No patient developed other evidence of neurological disease. The condition seems to be a benign, permanent condition limited in its manifestations to the superior oblique muscle.
mesh_terms: D000328:Adult; D002220:Carbamazepine / Q000627:therapeutic use; D005133:Eye Movements; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000175:diagnosis / Q000188:drug therapy; D009801:Oculomotor Muscles / Q000187:drug effects; D014202:Tremor / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D002220:Carbamazepine