title: Tuberous sclerosis: a survey of 97 cases. I: Seizures, pertussis immunisation and handicap.
abstract: The relationship between the onset of seizures, immunisation dates and degree of mental handicap was reviewed among children with tuberous sclerosis. Profound handicap occurred in those children who had an early onset of seizures. There was no evidence that pertussis vaccine caused additional brain-damage.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007114:Immunization / Q000009:adverse effects; D007223:Infant; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010567:Pertussis Vaccine / Q000009:adverse effects*; D012640:Seizures / Q000188:drug therapy / Q000209:etiology*; D013036:Spasms, Infantile / Q000209:etiology; D014402:Tuberous Sclerosis / Q000150:complications*
chemical_list: D010567:Pertussis Vaccine