title: NMR studies and GC analysis of the antibacterial agent taurolidine.
abstract: The NMR spectrum of taurolidine in deuterium oxide was compared with spectra obtained from model experiments with amines and formaldehyde. Head-space analysis combined with capillary GC showed that there was less than 0.004% free formaldehyde present in 2% solutions of taurolidine. This value is comparable to the concentration of formaldehyde found when the taurolidine solutions were injected directly onto GC columns.
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013654:Taurine / Q000031:analogs & derivatives*; D013829:Thiadiazines / Q000032:analysis*; D013843:Thiazines / Q000032:analysis*
chemical_list: D000890:Anti-Infective Agents; D013829:Thiadiazines; D013843:Thiazines; D013654:Taurine; C012566:taurolidine