[Basic research for visible laser unit for the spinal cord (a preliminary report)].
The cat's spinal dorsal column was irradiated unilaterally with Ar. laser of which power output was 500 mW and the spot size was 2 mm in diameter. The somatosensory evoked potentials (S.E.P.) were recorded bilaterally. In other cats, the fluorescein was injected intravenously for photoactivation and the dorsal column was irradiated with Ar. laser. The conclusion can be summarized as follows: 1) When the small demarcated area was made in the surface of the dorsal column by Ar. laser-irradiation, the early component of S.E.P. was disappeared. The histological finding revealed the destruction of the irradiated dorsal column. 2) The photoactivation effect of Ar. laser was demonstrated in the spinal cord, by using a fluorescein drug. The S.E.P. and the histological finding were the same as those of the nonfluorescein drug group. 3) The S.E.P. was available for the concept of the Laser-Photo-Biological-Effect (L.P.B.E.).
D000818:Animals; D002415:Cats; D005073:Evoked Potentials, Somatosensory; D007834:Lasers / Q000009:adverse effects; D013116:Spinal Cord / Q000033:anatomy & histology / Q000502:physiology*; D013119:Spinal Cord Injuries / Q000209:etiology