[Change in the surface charge of serum lipoproteins at the early stages of development of atherosclerosis].
By means of fluorescent probe 1-anilinonaphthalene-8-sulfonate the surface charge of serum lipoproteins of the rabbit kept on cholesterol diet was estimated. A week after the beginning of cholesterol diet the surface charge of low density lipoproteins becomes more positive as compared to the control. A change of the surface charge of protein-lipid particles of the blood serum is one of the primary causes of the development of atherosclerosis.
D000818:Animals; D001161:Arteriosclerosis / Q000097:blood*; D002791:Cholesterol, Dietary; D004036:Diet, Atherogenic; D008074:Lipoproteins / Q000097:blood* / Q000502:physiology; D011817:Rabbits; D013050:Spectrometry, Fluorescence
D002791:Cholesterol, Dietary; D008074:Lipoproteins
Izmenenie poverkhnostnogo zariada syvorotochnykh lipoproteidov na rannikh stadiiakh razvitiia ateroskleroza.