title: The use of tissue adhesive in corneal perforations.
abstract: Eighty patients with either corneal perforation or impending perforation were treated with the application of tissue adhesive that remained in place on the average of 50 days. Forty-four percent of these cases healed with the application of glue alone. Complications occurred in nine patients (11%). Two developed marked increase in intraocular pressure that was controlled with antiglaucoma medications and seven developed corneal infiltrates. Five of the infiltrates were culture-proven bacterial infections occurring on the average of 73 days after gluing. The relationships between diagnosis, duration of glue, and complications are reviewed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003263:Contact Lenses, Hydrophilic; D003316:Corneal Diseases / Q000601:surgery*; D003320:Corneal Ulcer / Q000601:surgery*; D003646:Debridement; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D014014:Tissue Adhesives