title: Linkage relationships between Retinoschisis, Xg, and a cloned DNA sequence from the distal short arm of the X chromosome.
abstract: A cloned DNA sequence, RC8, from the short arm of the X chromosome which is linked to the Duchenne muscular dystrophy (DMD) gene has been employed to study linkage relationships with the Xg-linked retinoschisis (RS) locus. Results of three point linkage analyses in two families suggest that the gene order on Xp is Xg-RS-RC8. Moreover, it can be inferred from these date that the genetic distance between Xg and DMD is approximately 55 cM.
mesh_terms: D000483:Alleles; D003001:Cloning, Molecular; D003434:Crossing Over, Genetic; D004247:DNA / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D010375:Pedigree; D010641:Phenotype; D012164:Retinal Diseases / Q000235:genetics*; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014960:X Chromosome / Q000648:ultrastructure
chemical_list: D004247:DNA