Oxidation of N-hydroxyphentermine to 2-methyl-2-nitro-1-phenylpropane by liver microsomes.
D000818:Animals; D001386:Azides / Q000494:pharmacology; D002374:Catalase / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005949:Glucose Oxidase / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010645:Phentermine / Q000031:analogs & derivatives* / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D014969:Xanthine Oxidase / Q000378:metabolism
D001386:Azides; C031069:2-methyl-2-nitro-1-phenylpropane; C013568:N-hydroxyphentermine; D003577:Cytochrome P-450 Enzyme System; D006861:Hydrogen Peroxide; D010645:Phentermine; D005949:Glucose Oxidase; D002374:Catalase; D014969:Xanthine Oxidase