Trichloroethylene vapours do not produce dominant lethal mutations in male mice.
Exposure of male mice to trichloroethylene vapours during 24 h at levels or 50, 202 and 450 ppm did not reveal mutagenic effects in the dominant lethal assay. The following parameters were registered and evaluated: Fertilization rate, post-implantation loss, preemplantation loss and dominant lethal mutations.
D000818:Animals; D010064:Embryo Implantation / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects; D005740:Gases; D005799:Genes, Dominant / Q000187:drug effects*; D005804:Genes, Lethal / Q000187:drug effects*; D008297:Male; D051379:Mice; D009153:Mutagens; D014241:Trichloroethylene / Q000633:toxicity*
D005740:Gases; D009153:Mutagens; D014241:Trichloroethylene