High-performance liquid chromatographic determination of reproterol in plasma using on-line trace enrichment and amperometric detection with a rotating working electrode.
A method is described to determine nanogram quantities of reproterol in plasma. It consists of deproteinization of the plasma samples, on-line trace enrichment, and liquid chromatographic separation of the compounds brought on the analytical column, coupled with amperometric detection. Reliable quantitation can be done down to levels of 1 ng/ml.
D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D004563:Electrochemistry / Q000295:instrumentation*; D004566:Electrodes; D006801:Humans; D008297:Male; D009921:Metaproterenol / Q000031:analogs & derivatives* / Q000097:blood / Q000302:isolation & purification; D008722:Methods; D013806:Theophylline / Q000031:analogs & derivatives* / Q000097:blood / Q000302:isolation & purification; D013997:Time Factors
D004338:Drug Combinations; C014792:reproterol; D009921:Metaproterenol; D013806:Theophylline