title: [Case of yolk sac tumor of the anterior mediastinum with superior vena cava syndrome].
abstract: The patient was a 21-year-old man with SVC syndrome due to a large anterior mediastinal mass. Following radiotherapy which improved his condition, thoracotomy was performed, however, total resection failed. Despite postoperative re-irradiation, his condition worsened rapidly and he died five months after the onset of his symptoms. The neoplasm was composed of a yolk sac tumor producing alpha-fetoprotein. Yolk sac tumors of the mediastinum are rare and lethal. Recent reports indicate that cis-platinum may be highly effective in germ cell tumors. Therefore, radiotherapy combined with cis-platinum may be improved the survival of patients with yolk sac tumor.
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D008649:Mesonephroma / Q000150:complications / Q000473:pathology / Q000628:therapy*; D013577:Syndrome; D014652:Vascular Diseases / Q000209:etiology; D014683:Vena Cava, Superior