Kinetics of the pretransition of synthetic phospholipids. A calorimetric study.
The pretransition in aqueous dispersions of two synthetic phospholipids (dimyristoylphosphatidylcholine and dipalmitoylphosphatidylcholine) has been examined in detail by differential scanning calorimetry. The transition from the high-temperature state (state above pretransition) to the low-temperature state (state below pretransition) is complex and appears to occur via some metastable states. In contrast, the kinetics of the transition from the low- to the high-temperature state is consistent with an activated two-state model. The observed hysteresis is shown to arise mainly from the kinetic nature of the pretransition.
D002152:Calorimetry, Differential Scanning; D004134:Dimyristoylphosphatidylcholine; D007700:Kinetics; D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D013696:Temperature
D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D004134:Dimyristoylphosphatidylcholine