Structural preferences of beta-galactoside-reactive lectins on Actinomyces viscosus T14V and Actinomyces naeslundii WVU45.
Specificities of lectins on Actinomyces viscosus T14V and Actinomyces naeslundii WVU45 were compared by measuring the abilities of D-galactose, N-acetyl-D-galactosamine, 14 beta-D-galacto-oligosaccharides, and 2 beta-D-fuco-oligosaccharides to inhibit coaggregation between Streptococcus sanguis 34 and each actinomycete. Inhibition profiles were similar, but WVU45 was significantly more sensitive to several inhibitors. D-Galactose-beta(1 leads to 3)-N-acetyl-D-galactosamine glycosides were most potent.
D000190:Actinomyces / Q000187:drug effects*; D000371:Agglutination / Q000187:drug effects; D003864:Depression, Chemical; D005697:Galactosides / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology*; D037102:Lectins / Q000494:pharmacology*; D013298:Streptococcus sanguis / Q000187:drug effects
D005697:Galactosides; D006027:Glycosides; D037102:Lectins; C007816:beta-galactoside