title: [Treatment of congenital hypothyroidism by L-thyroxine in solution. Posology].
abstract: A solution of levothyroxine (5 micrograms/drop) has been used in congenital hypothyroidism detected after neonatal screening. Optimal doses were variable among individual patients. With 5-7 micrograms/kg during the first month of treatment, then 4 to 5 micrograms/kg, it was usually possible to obtaining normal plasma T4, which seems more important that to normalize TSH. Overdosage is to be avoided as well as insufficiency of treatment.
mesh_terms: D000284:Administration, Oral; D002648:Child; D003409:Congenital Hypothyroidism; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy; D008297:Male; D012996:Solutions; D013974:Thyroxine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D012996:Solutions; D013974:Thyroxine
vernacular_title: Traitement des hypothyroïdies congénitales par la L-thyroxine en solution. Posologie.