Microscopic evaluation of the sequential degeneration and repair of the retinae of albino mice after high-dose laser irradiation.
After irradiation of the retinae of albino mice with a dose of 13 J, using a ruby pulse laser, the lesions were followed for a period of 60 days. Severe degenerations were observed in the outer layer 2-9 days after irradiation. By the 21st day after irradiation, the pigment epithelium started to regenerate and outer segments began to reform. Progressive recovery and repair were by and large completed by the 60th day after irradiation.
D000818:Animals; D007834:Lasers; D051379:Mice / Q000502:physiology*; D008813:Mice, Inbred ICR; D009410:Nerve Degeneration; D009416:Nerve Regeneration / Q000528:radiation effects*; D012160:Retina / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure; D013997:Time Factors