title: [Unilateral blindness following intranasal aethoxysklerol injection].
abstract: In spite of extensive experience based on animal experiments and human treatment, a unilateral, irreversible amaurosis occurred in one case of paravascular sclerotherapy of epistaxis with Aethoxysklerol. The strict submucosal application of Aethoxysklerol does not cause a mural thrombosis but leads to narrowing of the vessels (e.g., in the region of the Locus Kiesselbachii) due to gradual subepithelial sclerosis of the mesenchymal tissue. Temporary or permanent amaurosis has also been described in cases of injection of local anesthetics or glucocorticoid crystalline suspensions in the facial and neck region. From the pathophysiological point of view, allergic reactions, neuroreflex vascular spasm, or micro embolism of the central retinal artery have to be considered. The incident on which this paper is based led to a liability lawsuit. Judgement was given against the attending doctor because of severe bodily injury.
mesh_terms: D000328:Adult; D001766:Blindness / Q000139:chemically induced*; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy; D006801:Humans; D008318:Malpractice; D009668:Nose Diseases / Q000188:drug therapy; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects*; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D012597:Sclerosing Solutions; D000077423:Polidocanol; D011092:Polyethylene Glycols
vernacular_title: Einseitige Erblindung nach Intranasaler Aethoxysklerol-Injektion.