title: [Peri-focal administration of OK-432 combined with radiotherapy in the treatment of esophageal cancer].
abstract: We have been interested in direct activity of OK-432 on cancer lesion and applied a combined therapy of perifocal administration of OK-432 with radiation for 2 cases as a new trial. Following results were obtained. Histological efficacy as Ef3 at resected specimen was observed in one case and complete regression of cancer lesion was confirmed by X-ray, fiber scope and biopsy after combined therapy of perifocal administration of 10 KE of OK-432 with radiation of 2400 rad in total.
mesh_terms: D000368:Aged; D001688:Biological Products / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008297:Male; D010844:Picibanil / Q000008:administration & dosage*
chemical_list: D001688:Biological Products; D010844:Picibanil