title: [Technic and value of the carbachol nasal test in vasomotor rhinopathies].
abstract: The carbacholine nasal test assesses "nasal hyperreactivity", particularly its parasympathetic component, in vasomotor rhinopathies. This simple, reproducible test has been applied to two groups of subjects: a group of 26 healthy subjects without any rhinopharyngeal and/or allergic affections, and 10 patients with aperiodic non-allergic (6 cases) or allergic (4 cases) vasomotor rhinopathy, the 4 cases with allergy including 3 allergic to house dust mite and one to house dust mite and grass pollen. Nasal reactivity to carbacholine was evaluated by measuring the amount of rhinorrhea following variable concentrations (1/1000, 1/100, 1/25) and volumes (0,10 to 0,50 ml) of carbacholine solution. Nasal secretion was markedly increased in patients with a vasomotor rhinopathy (1.80 +/- 0.65 ml) when compared with control subjects (0.64 +/- 0.17 ml). The main conclusions to be drawn from this study, and possible applications of this test in rhinology are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D002217:Carbachol; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000378:metabolism; D009299:Nasal Provocation Tests / Q000379:methods*; D012223:Rhinitis, Vasomotor / Q000175:diagnosis*
chemical_list: D002217:Carbachol
vernacular_title: Technique et intérêt du test nasal à la carbacholine dans les rhinopathies vasomotrices.