Neonatal neuroblastoma metastatic to the iris.
A newborn infant was found to have Stage IVS retroperitoneal neuroblastoma. Multiple iris nodules were present at birth and regressed in synchrony with the primary tumor mass as chemotherapy was administered. A summary of the ocular manifestations of neuroblastoma is presented. A discussion of the possible significance of the iris lesions in this case is given. As far as we are aware, this is the first case report of neuroblastoma metastatic to the iris.
D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007499:Iris Diseases / Q000188:drug therapy / Q000473:pathology*; D009447:Neuroblastoma / Q000151:congenital / Q000473:pathology / Q000556:secondary*; D012186:Retroperitoneal Neoplasms / Q000151:congenital* / Q000473:pathology; D014604:Uveal Neoplasms / Q000188:drug therapy / Q000556:secondary*