Autoradiographic and ultrastructural studies on the human fibro-atheromatous plaque.
Foam cells, either myogenic or macrophagic, are commonly detected in experimental and human fibro-atheromatous plaques. Their role in human atherosclerosis is not yet understood. This paper reports on a preliminary autoradiographic study combined with ultrastructural observations in the human fibro-atheromatous plaque. Most of the autoradiographic silver grains appeared on foam cells and monocyte-like cells, thus suggesting a local proliferation of these cells.
D001157:Arterial Occlusive Diseases / Q000473:pathology*; D001161:Arteriosclerosis / Q000473:pathology*; D001345:Autoradiography; D004727:Endothelium / Q000473:pathology; D005352:Fibromuscular Dysplasia / Q000473:pathology*; D005487:Foam Cells / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D009131:Muscle, Smooth, Vascular / Q000473:pathology