title: Disseminated intravascular coagulation in carcinoma of prostate: role of estrogen therapy.
abstract: Advanced carcinoma of the prostate may present as disseminated intravascular coagulation and its sequelae. It is postulated that the slow release of thromboplastic material from tumor cells eventually overcomes normal homeostatic mechanisms. High-dose intravenous diethylstilbestrol diphosphate successfully reversed this coagulopathy in 2 cases of metastatic carcinoma of the prostate.
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000150:complications*; D004054:Diethylstilbestrol / Q000008:administration & dosage / Q000627:therapeutic use*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000150:complications*
chemical_list: D004054:Diethylstilbestrol