title: Early changes in the adaptation to a low calcium diet in the chick.
abstract: Twelve hours after the diet of 3-week-old chicks was changed from a 1% to a 0.1% concentration of calcium (Ca), the growth rate and circulating levels of growth hormone had fallen while renal 25-hydroxecholecalciferol-24-hydroxylase had risen. The amount of 47Ca incorporated into bone from an injection given 18 h previously was lower than in the control birds. Over the following 2 1/2 days on the low Ca diet, the renal 1-hydroxylase activity rose and the plasma prolactin level fell, but the other parameters moved back toward the control level. It was concluded that early adjustments in hormonal and mineral metabolism counteract the acute effects of a dietary Ca shortage until longer-term adaptive changes begin to compensate for a continuing Ca deficiency. The renal hydroxylase activities were not directly influenced by the level of circulating growth hormone or prolactin.
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001835:Body Weight; D002118:Calcium / Q000097:blood / Q000172:deficiency*; D002136:Calcium, Dietary / Q000008:administration & dosage; D002645:Chickens; D013006:Growth Hormone / Q000097:blood; D008297:Male; D006899:Mixed Function Oxygenases / Q000097:blood
chemical_list: D002136:Calcium, Dietary; D013006:Growth Hormone; D006899:Mixed Function Oxygenases; D002118:Calcium