[Induced resistance to kanamycin and tetracycline in Rhizobium japonicum].
Spontaneous mutants Km-R and Tc-R of R. japonicum with various levels of resistance to kanamycin (0.8-20 mg/ml) and tetracycline (130-210 micrograms/ml) were isolated. No cross resistance in the mutants was observed. Plasmid R68.45 transferred to the wild strains resistance to 210 micrograms/ml of tetracycline and to 20 mg/ml of kanamycin. This plasmid did not practically increase the resistance to tetracycline in mutants Tc-R. At the same time it markedly increased the resistance to kanamycin in mutants Km-R.
D004352:Drug Resistance, Microbial; D007612:Kanamycin / Q000037:antagonists & inhibitors*; D008826:Microbial Sensitivity Tests; D009154:Mutation; D010957:Plasmids / Q000187:drug effects; D012231:Rhizobium / Q000187:drug effects*; D013752:Tetracycline / Q000037:antagonists & inhibitors*
D007612:Kanamycin; D013752:Tetracycline
Indutsirovannaia ustoĭchivost' k kanamitsinu i tetratsiklinu u Rhizobium japonicum.