[Effects of intrapartum steroid prophylaxis on complement C3 and total complement activities (author's transl)].
One single high dose of dexamethasone (0.5 mg/kg body weight) was administered to a mother, before tests started into the effects of such approach upon the serum total complement (CH 50) and C-3 levels in the mother's umbilical cord blood. Neither CH 50 nor C-3 complement had declined with significance 48 hours from steroid administration. Significant reduction was observed only in cases in which six hours elapsed between steroid administration and childbirth.
D003176:Complement C3 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis*; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control
D003176:Complement C3; D003907:Dexamethasone; D003165:Complement System Proteins
Der Einfluss der Steroidprophylaxe unter der Geburt auf die Komplement C3- und Gesamtkomplement-Aktivität.