Activity and storage stability of proteins in a hepatitis-free human serum preparation.
The activity of certain selected serum proteins was investigated in Biseko, a product prepared from beta-propiolactone/UV treated, pooled human plasma. It was shown that the biological activity of the immunoglobulins, transport proteins and inhibitor proteins was not affected by the manufacturing process. With the exception of alpha 1-antitrypsin and coeruloplasmin, the biological activity of the proteins studied proved to be preserved on storage at 37 degrees C.
D000906:Antibodies / Q000032:analysis; D001793:Blood Preservation; D001798:Blood Proteins / Q000032:analysis*; D002352:Carrier Proteins / Q000032:analysis; D002802:Cholinesterases / Q000097:blood; D004355:Drug Stability; D004791:Enzyme Inhibitors / Q000097:blood; D006505:Hepatitis / Q000517:prevention & control*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D011485:Protein Binding
D000906:Antibodies; D001798:Blood Proteins; D002352:Carrier Proteins; D004791:Enzyme Inhibitors; D007136:Immunoglobulins; D002802:Cholinesterases