M-9337, a new antistreptolysin, produced by Streptomyces sp.
A new biologically active substance, M-9337, was obtained from Streptomyces strain M-9337, a soil isolate. The producing organism was subsequently determined to be a new strain and named Streptomyces antihaemolyticus M-9337. The active substance was prepared as white yellow powder from culture broth by solvent extraction and silica gel thin-layer chromatography. It showed no antimicrobial activity and potent inhibitory activity against streptolysin, a type of hemolysin.
D000989:Antistreptolysin / Q000302:isolation & purification*; D002852:Chromatography, Ion Exchange / Q000379:methods; D003470:Culture Media; D012988:Soil Microbiology; D013053:Spectrophotometry; D013301:Streptolysins / Q000037:antagonists & inhibitors*; D013302:Streptomyces / Q000254:growth & development*
D003470:Culture Media; D013301:Streptolysins; C031774:M-9337; D000989:Antistreptolysin