An appraisal of polymerized pyridoxylated hemoglobin as an acellular oxygen carrier.
Polymerized pyridoxylated hemoglobin provides a means of obtaining an acellular oxygen carrier that can be infused at a normal hemoglobin concentration, with a normal COP and is stable in vivo. We have also shown that rats can survive a total exchange transfusion with poly SFH-P (Sehgal et al, 1980). It thus become a prime candidate for further in vivo assessment of its oxygen transport characteristics.
D001802:Blood Substitutes / Q000494:pharmacology*; D006454:Hemoglobins / Q000494:pharmacology*; D006801:Humans; D008970:Molecular Weight; D009997:Osmotic Pressure; D011108:Polymers / Q000494:pharmacology*; D011730:Pyridoxal
D001802:Blood Substitutes; D006454:Hemoglobins; D011108:Polymers; D011730:Pyridoxal