title: [Platelet aggregation in workers chronically exposed to carbon disulfide and subjected to prophylactic treatment with Cynarex].
abstract: 62 men producing artificial fibres were administered for 2 years an artichoke extract as a preparation called Cynarex, produced by the Herbs Plant, Herbapol" in Wrocław. The spontaneous and ADP-induced platelets aggregation was examined by the method of Holdrinet et al. The platelets ability to aggregate, whether spontaneously or by induction was found to be statistically significantly reduced. The spontaneous aggregation after two years of Cynarex administration was reduced on average by 51%.
mesh_terms: D000328:Adult; D000393:Air Pollutants / Q000633:toxicity*; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D000925:Anticoagulants; D002246:Carbon Disulfide / Q000633:toxicity*; D002934:Cinnamates / Q000627:therapeutic use; D004338:Drug Combinations / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000517:prevention & control; D010974:Platelet Aggregation / Q000187:drug effects*; D013927:Thrombosis / Q000139:chemically induced / Q000517:prevention & control; D013997:Time Factors
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D000925:Anticoagulants; D002934:Cinnamates; D004338:Drug Combinations; C100257:cynarine; D002246:Carbon Disulfide
vernacular_title: Agregacja płytek krwi u pracowników narazonych na przewlekłe działanie dwusiarczku wegla i poddanych profilaktyce preparatem cynarex.