title: [Regulation of the breathing pattern during muscle activity under normal and altered chemoreceptor stimulation].
abstract: The quantitative relations between the tidal volume and timing of the respiratory cycle (breathing pattern) in resting and with gradual muscular loads, were investigated in 16 healthy subjects under conditions of normal and altered chemoreceptive respiratory drive. The human breathing pattern during muscular exercise was shown to reflect the features of the central respiratory rhythmogenic mechanisms which depend on the interaction among stimuli of different modalities. In turn the effects of these stimuli are significantly modulated by the biomechanical factors and thus are subject to considerable individual variations: the augmentation of ventilation induced by increasing of work intensity is mainly due to the tidal volume rise or alternatively to the increased breathing frequency in the representatives of "tachypnoic" or "bradypnoic" breathing patterns, respectively.
mesh_terms: D000328:Adult; D002628:Chemoreceptor Cells / Q000502:physiology*; D006801:Humans; D006935:Hypercapnia / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology; D008176:Lung Volume Measurements; D008297:Male; D009132:Muscles / Q000502:physiology*; D005082:Physical Exertion; D012119:Respiration; D012146:Rest; D013997:Time Factors; D014939:Work of Breathing
vernacular_title: Reguliatsiia patterna dykhaniia pri myshechnoĭ deiatel'nosti v usloviiakh normal'noĭ i izmenennoĭ khemoretseptornoĭ stimuliatsii.