title: A comparative study of lens gamma crystallins using isoelectric focusing.
abstract: The isoelectric points of gamma crystallins of the lenses of rats, dogfish, calves, and humans differ, with a range of pH 8.87-6.80. In each species, one gamma crystallin component with an isoelectric point at pH 7.5 is present, but at differing levels. Amino acid compositions of this component were similar among these four species. All pH 7.5 isoelectric point proteins crossreact immunochemically. A common messenger RNA must be present for this gamma crystallin in all of these species.
mesh_terms: D000368:Aged; D000596:Amino Acids / Q000302:isolation & purification; D000818:Animals; D002415:Cats; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D003459:Crystallins / Q000235:genetics / Q000302:isolation & purification*; D004284:Dogfish; D006801:Humans; D007525:Isoelectric Focusing; D007908:Lens, Crystalline / Q000032:analysis*; D008875:Middle Aged; D012333:RNA, Messenger / Q000302:isolation & purification; D051381:Rats; D013045:Species Specificity
chemical_list: D000596:Amino Acids; D003459:Crystallins; D012333:RNA, Messenger