title: Mucosal lesions in the rat associated with the attachment of Moniliformis (Acanthocephala).
abstract: By means of scanning electron microscopy, aspects of the attachment of Moniliformis dubius (Acanthocephala) to the intestinal wall of the rat are described together with various changes in the structure and form of the mucosa. Attachment of the parasite results in the formation of a distinct pit around the everted proboscis and a crater around the neck. Contact between the anterior region of the trunk of the worm and the intestine of the host appears to lead to villous fusion so that characteristic grooves are formed in the mucosal tissue. Evidence was also obtained to suggest that host goblet cells may become exhausted during the course of an infection with Moniliformis.
mesh_terms: D000049:Acanthocephala / Q000502:physiology*; D000818:Animals; D006373:Helminthiasis / Q000469:parasitology* / Q000473:pathology; D006790:Host-Parasite Interactions; D007413:Intestinal Mucosa / Q000469:parasitology* / Q000648:ultrastructure; D007421:Intestine, Small / Q000469:parasitology; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D008990:Moniliformis / Q000502:physiology*; D051381:Rats