title: [Formal cause of stomach ulcer].
abstract: Analysing gastric circulation we find that the hemodynamic effects of acid secretion and wall stress during contractions are capable of producing malperfusion of discrete areas. A computer-aided simulation of digestive cycles on a simplified gastric model shows an ischemic lesion, corresponding with the phenomenology of human gastric ulcer. A steal-phenomenon, which the effect is due to, has been produced experimentally.
mesh_terms: D000818:Animals; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D005769:Gastrointestinal Motility; D006801:Humans; D007511:Ischemia / Q000150:complications; D008954:Models, Biological; D013270:Stomach / Q000098:blood supply / Q000502:physiology; D013276:Stomach Ulcer / Q000209:etiology*
vernacular_title: Zur Formursache des Magengeschwürs.