[Serum HPL, total estrogen excretion and serum oxytocinase in intrauterine retardation. Results of 3 evaluation procedures].
The purpose of this study was to check the value of the determinations of human placental lactogen (HPL), urinary total estrogens and oxytocinase in 40 patients with fetal growth retardation among 253 single pregnancies using 3 methods of interpretation. The false-positive (abnormal) error of HPL was 40.4%. The sensitivity of urinary total estrogens was 22,5%, and of oxytocinase 30,8%. Therefore the intrauterine growth retardation can be predicted only in about a quarter of cases showing low levels or atypical profiles of these both biochemical determinations. The results suggest that the practical value is limited for all three determinations.
D000626:Aminopeptidases / Q000097:blood*; D010122:Cystinyl Aminopeptidase / Q000097:blood*; D004967:Estrogens / Q000652:urine*; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000201:enzymology*; D005323:Fetal Monitoring; D006801:Humans; D010928:Placental Lactogen / Q000097:blood*; D011247:Pregnancy
D004967:Estrogens; D010928:Placental Lactogen; D000626:Aminopeptidases; D010122:Cystinyl Aminopeptidase
HPL im Serum, Gesamtöstrogenausscheidung und Serumoxytocinase bei intrauteriner Retardierung. Ergebnisse von 3 Auswertungsverfahren.