Dentition of a 48,XYY,+21 male.
Although the dentition of a 48,XYY,+21 male showed some typical features of Down's syndrome, metric analysis indicated a marked increase in tooth size particularly for early developing teeth. The extra Y chromosome can influence phenotypic expression, overcoming the superimposed effects of the additional 21 chromosome.
D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002904:Chromosomes, Human, 21-22 and Y; D003817:Dentition; D006801:Humans; D008297:Male; D012729:Sex Chromosome Aberrations / Q000473:pathology*; D014998:Y Chromosome / Q000502:physiology