[Pulmonary metastasis of renal cell carcinoma].
I treated 116 patients with pulmonary metastasis from renal cell carcinoma (312 cases). My experience with anticancer chemotherapy indicates that complete response was elicited in 1/15, 0/14, 0/10, 1/6, 0/5 and 0/20 of cases receiving Ft-207, CCNU, vinblastine, adriamycin, ifosfamide and MFC, respectively. Progesterone therapy produced complete response in one of 60 and partial response in 2 of 60. Interferon therapy was effective in 2 of 10 cases. Surgical removal of pulmonary metastatic lesion was done in only 6% (7/116) of cases, which was worth trying especially in low grade cases. The 3 and 5 year survival Jap. rates for the entire 116 cases were 20% and 6%, respectively.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D004317:Doxorubicin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007370:Interferon Type I / Q000008:administration & dosage; D007680:Kidney Neoplasms; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011374:Progesterone / Q000008:administration & dosage; D014747:Vinblastine / Q000008:administration & dosage
D000970:Antineoplastic Agents; D007370:Interferon Type I; D011374:Progesterone; D014747:Vinblastine; D004317:Doxorubicin; D005472:Fluorouracil; D007069:Ifosfamide