Effects of beta-chlornaltrexamine on separation distress in chicks.
Intraventricular B-chlornaltrexamine (2 micrograms) increased distress vocalizations (DVs) in chicks, and reduced the ability of intraventricular morphine (.1-.5 micrograms), to inhibit DVs. Object imprinting was not blocked by central CNA, but systemic naloxone (10 mg/kg) did attenuate imprinting to a green but not a red object.
D000818:Animals; D001010:Anxiety, Separation / Q000503:physiopathology*; D001921:Brain / Q000187:drug effects; D002645:Chickens; D006801:Humans; D007276:Injections, Intraventricular; D009020:Morphine / Q000494:pharmacology; D009270:Naloxone / Q000031:analogs & derivatives*; D009271:Naltrexone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology*
D009292:Narcotic Antagonists; D009270:Naloxone; D009271:Naltrexone; C017120:chlornaltrexamine; D009020:Morphine