Porcine malignant hyperthermia. IX: Changes in the concentrations of intramuscular high-energy phosphates, glycogen and glycolytic intermediates.
A technique of obtaining muscle biopsies with a liquid nitrogen cryoprobe was used to study intramuscular metabolites in MH-susceptible and unsusceptible pigs. There was no significant difference in muscle metabolite values obtained from susceptible and unsusceptible pigs in the resting state. During MH the changes in metabolites were a result of rapid glycogenolysis and no abnormality of glycolytic control was observed.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D003401:Creatine / Q000378:metabolism; D006003:Glycogen / Q000378:metabolism; D007773:Lactates / Q000378:metabolism; D008305:Malignant Hyperthermia / Q000662:veterinary*; D009132:Muscles / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D013552:Swine; D013553:Swine Diseases / Q000378:metabolism*
D007773:Lactates; D010710:Phosphates; D010725:Phosphocreatine; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D006003:Glycogen; D003401:Creatine