Evans Blue disappearance rate in normal and pre-eclamptic pregnancy.
The disappearance rate of intravenously injected Evan's Blue dye from the circulation (EBDR) has been studied in 21 normotensive primigravidae and 23 primigravidae with proteinuric pre-eclampsia. The EBDR is faster in those with pre-eclampsia and results in differences in plasma volume in pre-eclamptics depending on the method of calculation. The EBDR correlates with serum albumin concentration and total body water in pre-eclamptics, but not in normotensive pregnancies.
D001391:Azo Compounds / Q000008:administration & dosage*; D001834:Body Water / Q000032:analysis; D002199:Capillary Permeability; D005070:Evans Blue / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D010953:Plasma Volume; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology; D011507:Proteinuria / Q000150:complications / Q000503:physiopathology; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors
D001391:Azo Compounds; D012709:Serum Albumin; D005070:Evans Blue