Local cerebral alterations in [14C-2]deoxyglucose uptake following memory formation.
In order to show changes in the local cerebral glucose utilization during an avoidance task, dry-autoradiography with [14C]deoxyglucose was employed in the present work. The following regions showed increased radioactivity following the avoidance task: nucleus ventralis thalami of the pars medialis and lateralis thalami, corpus striatum, nucleus periventricularis hypothalami, paraflocculus, stratum lacuno-moleculare, and nucleus lateralis septi. Among other regions, the stratum lacuno-moleculare of area CA1 and CA2 of the hippocampus showed increased activity apparently related to the memory formation.
D000818:Animals; D001345:Autoradiography; D001362:Avoidance Learning / Q000502:physiology*; D001921:Brain / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D002250:Carbon Radioisotopes; D002540:Cerebral Cortex / Q000378:metabolism; D003837:Deoxy Sugars / Q000378:metabolism*; D003847:Deoxyglucose / Q000378:metabolism*; D004027:Diencephalon / Q000378:metabolism; D008297:Male; D008636:Mesencephalon / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains
D002250:Carbon Radioisotopes; D003837:Deoxy Sugars; D003847:Deoxyglucose