title: Belgian heart disease prevention project: comparison of self-reported smoking behaviour with serum thiocyanate concentrations.
abstract: At the end of a multifactorial cardiovascular preventive trial serum thiocyanate was measured in random samples of 1035 cases and 1087 controls. A cut-off point 0.45 mg/dl (77.6/mumol/l) gave a sensitivity of 82.1% among the cigarette smokers in the control group and a specificity of 91.0% among the non-smokers. When the intervention and control groups are compared in terms of self-reported smoking behaviour non-significant differences in mean thiocyanate concentration are observed for those who never smoked, ex-cigarette smokers, actual cigarette smokers, and in four different cigarette smoking categories. Our results fail to confirm the reported pessimistic views concerning the validity of self-reported smoking behaviour in subjects taking part in intervention trials.
mesh_terms: D000328:Adult; D001530:Belgium; D006331:Heart Diseases / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012306:Risk; D012907:Smoking; D013861:Thiocyanates / Q000097:blood*; D014342:Truth Disclosure
chemical_list: D013861:Thiocyanates