title: Effects of glucose, anoxia, and adriamycin on the chemiluminescence of Ehrlich Ascites cells.
abstract: Glucose and anoxia accelerate the photocount due to luminescence of Ehrlich Ascites cells. Adriamycin also has this effect if glucose is present. Comparison with a chemical standard combined with estimates of cellular and population transmittance yield a photon generation rate of at least 10 . s-1 . cell-1 in the presence of 10(-2) M glucose, and twice this with anoxic conditions or 10(-5) M adriamycin. Effects of adriamycin on Ehrlich Ascites cell respiration may depend on the presence of glucose.
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000503:physiopathology*; D002455:Cell Division / Q000187:drug effects; D004317:Doxorubicin / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology*; D000860:Hypoxia / Q000503:physiopathology*; D007700:Kinetics; D049449:Luminescence; D051379:Mice
chemical_list: D004317:Doxorubicin; D005947:Glucose