title: [Rubomycin complexing with copper (II)].
abstract: Complexing of rubomycin (H2R) with copper ions (II) in aqueous solutions was studied on the basis of fluorimetric and photometric measurements. H2R interacted with Cu (OH)+ to form the complex CuR with the molar extinction coefficient Ek = 4 . 96 . 10(3) and the stability 1g beta k = 5.54 +/- 0.09. The method of determining H2R in biological materials has been developed. It is based on the ability of the copper entering the complex to extinguish fluorexon luminescence in aqueous solutions.
mesh_terms: D000818:Animals; D003300:Copper / Q000494:pharmacology*; D003630:Daunorubicin / Q000032:analysis / Q000494:pharmacology*; D004347:Drug Interactions; D008433:Mathematics; D008892:Milk / Q000032:analysis; D010783:Photometry / Q000379:methods; D012996:Solutions; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D012996:Solutions; D003300:Copper; D003630:Daunorubicin
vernacular_title: Kompleksoobrazovanie rubomitsina s med'iu (II).