title: Angioedema responding to antiprotease treatment but without abnormalities of the complement system.
abstract: Four patients suffered from chronic or recurrent angioedema, of sudden onset in adult life, associated with visceral pain and impossible to control by dietary means. In spite of normal complement function they respond very well to tranexamic acid therapy. Antiprotease drugs need not be restricted to cases of ClsINH deficiency.
mesh_terms: D000328:Adult; D000614:Aminocaproates / Q000627:therapeutic use; D000799:Angioedema / Q000188:drug therapy*; D001780:Blood Coagulation Tests; D003172:Complement C1; D003176:Complement C3; D003181:Complement C4; D011415:Complement Factor B; D003165:Complement System Proteins; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D011480:Protease Inhibitors / Q000627:therapeutic use*; D014148:Tranexamic Acid / Q000627:therapeutic use
chemical_list: D000614:Aminocaproates; D003172:Complement C1; D003176:Complement C3; D003181:Complement C4; D011480:Protease Inhibitors; D014148:Tranexamic Acid; D003165:Complement System Proteins; D011415:Complement Factor B