title: [Mathematical model of the mechanism of respiratory rhythmogenesis].
abstract: Contemporary ideas of the mechanism of respiratory rhythmogenesis are considered. A mathematical model of these mechanisms is described as well as the results of its study underlying a proposed scheme of neuronal network which is able to maintain a regular alternation of respiratory phases within the wide range of physiological states. Three neuronal pools constitute the basis of the proposed network: the inspiratory neurons I alpha and I beta (the former excite the latter) and the added pool of expiratory neurons Ee which can be excited by the I beta neurons and inhibits the I alpha neurons. Presence of the Ee pool enables to obtain stable expiratory inhibition of the I alpha neurons. The model takes into consideration the proexpiratory effect of the lungs' stretch receptors as well as the proinspiratory action of the irritant receptors.
mesh_terms: D000818:Animals; D002628:Chemoreceptor Cells / Q000502:physiology; D006801:Humans; D008168:Lung / Q000294:innervation; D008433:Mathematics; D008465:Mechanoreceptors / Q000502:physiology; D008959:Models, Neurological; D009068:Movement; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology; D010507:Periodicity; D012119:Respiration
vernacular_title: Matematicheskaia model' mekhanizma dykhatel'nogo ritmogeneza.