[Studies on tumor markers using new anti-carbohydrate antibodies].
Reactivity of an antiserum against Fucose alpha-1 leads to 3 galactose linkage conjugated with bovine serum albumin to human colon adenocarcinoma was examined by indirect immunofluorescence using the frozen section of the specimen. Out of 30 cases examined, 22 cases expressed the antigen recognized by the antiserum, while non-carcinoma region was reactive in no case. Thus, the antigen (termed as FG 3 antigen) may be expected to be valuable in immunological diagnosis and even in immunotherapy of colon cancers.
D000230:Adenocarcinoma / Q000032:analysis; D000818:Animals; D000912:Antibodies, Neoplasm / Q000276:immunology; D000951:Antigens, Neoplasm / Q000032:analysis*; D003110:Colonic Neoplasms / Q000032:analysis; D051379:Mice; D009844:Oligosaccharides / Q000276:immunology*
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D009844:Oligosaccharides; C035714:3'-fucosyllactose