[Circulating anticoagulant, recurrent abortions and venous thrombosis: a new entity or a pre-lupus syndrome? 2 cases].
The authors report the presence of a circulating anticoagulant in two patients who had suffered multiple abortions. The circulating anticoagulant was discovered during evaluation of repeated phlebothromboses in the first case and of a chronic inflammatory syndrome in the second. While the apparently paradoxical relationship between the circulating anticoagulant and venous thrombosis is relatively well-known, that between the circulating anticoagulant and repetitive abortions is more difficult to establish. The rarely reported association of these three events leads us to a discussion of the nosologic place of this pathology and of the common ground it shares with S. L. E., as the circulating anticoagulant is of the antiprothrombinase variety, the antibody commonly called the lupus anticoagulant.
D000026:Abortion, Habitual / Q000503:physiopathology*; D000328:Adult; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000503:physiopathology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000503:physiopathology*; D011247:Pregnancy; D013577:Syndrome; D013924:Thrombophlebitis / Q000503:physiopathology*
Anticoagulant circulant, avortements à répétition et thromboses veineuses: entité nouvelle ou syndrome prélupique? Deux observations.