[Effect of clofibrate on the enzyme activity of the rat small intestine epithelium].
The effect of chronic administration of clofibrate on the enzyme activity of male rat small intestine homogenate was studied. The activities of peroxisomal and mitochondrial fatty acyl-CoA beta-oxidation enzymes were induced by clofibrate treatment. The activities of catalase, carnitine acetyltransferase and some other enzymes were also increased. Clofibrate did not affect the polypeptide composition of the "post-nuclear" small intestine homogenate.
D000818:Animals; D002332:Carnitine O-Acetyltransferase / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D002994:Clofibrate / Q000494:pharmacology*; D004848:Epithelium / Q000187:drug effects / Q000201:enzymology; D044943:Fatty Acid Desaturases / Q000378:metabolism*; D007421:Intestine, Small / Q000201:enzymology*; D007700:Kinetics; D008297:Male; D051381:Rats
D002374:Catalase; D044943:Fatty Acid Desaturases; D002332:Carnitine O-Acetyltransferase; D002994:Clofibrate
Vliianie klofibrata na aktivnosti fermentov épiteliia tonkogo kishechnika krysy.