Oral absorption of bendazac lysine salt in man after repeated administrations.
The plasma levels of the lysine salt of bendazac were studied in man after repeated administrations. The substance was administered in 500 mg tablets three times daily for 21 days. Concentrations of bendazac ranging between 15 and 30 micrograms/ml were found in the plasma within 10 hours after the first administration. No significant differences were observed between the first and following days of treatment. Common laboratory and clinical tests did not show any marked change.
D000284:Administration, Oral; D000328:Adult; D001774:Blood Chemical Analysis; D005260:Female; D006801:Humans; D007191:Indazoles / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D007408:Intestinal Absorption; D007700:Kinetics; D008297:Male; D011720:Pyrazoles / Q000378:metabolism*; D013997:Time Factors
D007191:Indazoles; D011720:Pyrazoles; C036067:bendazac lysine