Immunostimulating substances from human casein.
Delipidated human casein was digested with trypsin and the enzymatic digest was fractionated on Sephadex G-50. The peptidic fractions were assayed for immunomodulating activity in two in vitro models. Fractions corresponding to molecular weights in the range of 2,000 +/- 600 were found to possess stimulating activity in these models.
D000276:Adjuvants, Immunologic / Q000302:isolation & purification* / Q000494:pharmacology; D000921:Antibody-Producing Cells / Q000276:immunology; D002364:Caseins / Q000276:immunology*; D002850:Chromatography, Gel; D006801:Humans; D008970:Molecular Weight; D010455:Peptides / Q000302:isolation & purification; D010587:Phagocytosis; D014357:Trypsin / Q000494:pharmacology
D000276:Adjuvants, Immunologic; D002364:Caseins; D010455:Peptides; D014357:Trypsin