title: The possibilities of scintigraphic visualization of surfactants in the lung of the rat.
abstract: Incorporation of radioactive iodine into the surfactant system of the rat lung has been studied. Specially prepared particles labelled by 125I-oleic acid or 131I-oleic acid were injected intravenously and the distribution of radioiodine in the body of the animals was observed at various time intervals by means of a gamma camera and a gamma counter. The results showing appreciable accumulation of isotope in the lungs and the surfactant phospholipids, constitute a basis for the development of a new scintigraphic method for studying metabolic functions and morphology of the lung.
mesh_terms: D000818:Animals; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000032:analysis; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008863:Microspheres; D009829:Oleic Acids / Q000008:administration & dosage; D011663:Pulmonary Surfactants; D011877:Radionuclide Imaging; D051381:Rats; D014018:Tissue Distribution
chemical_list: D007457:Iodine Radioisotopes; D009829:Oleic Acids; D011663:Pulmonary Surfactants