title: Brain abscess in childhood. A study of 34 cases treated by puncture and antibiotics.
abstract: During the last 15 years, 34 children were treated for a brain abscess. 13 (38%) had cyanotic heart disease; 12 (35%) had an ENT infection. The standardized treatment protocol included puncture of the abscess and administration of antibiotic and antiedematous drugs. Postoperative permanent epidural monitoring of intracranial pressure and, in the last 5 years, repeated CT scans indicated if retapping the abscess or reinforcing the antiedematous treatment was necessary. In 7 out of these 34 cases the abscess had to be excised. Postoperative mortality rate was 6%. Overall mortality rate was 12%. Neurological sequelae were slight. Epilepsy frequency was 10%. Mental retardation (18%) was found only in cyanotic congenital heart disease to which it is related. Repeated CT scans demonstrated the progressive disappearance of the capsule within a few months. This study shows an improvement in the results when brain abscesses in children are punctured rather than excised.
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001922:Brain Abscess / Q000628:therapy*; D001929:Brain Edema / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004322:Drainage / Q000379:methods*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D007427:Intracranial Pressure / Q000187:drug effects; D008297:Male; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents