[Oxidative phosphorylation in pulmonary mitochondria after massive blood loss and restitution by autologous transfusion].
A procedure is described for isolation and polarographic study of rabbit lung mitochondria exhibiting high respiratory control as well as coupling of oxidation and phosphorylation approaching the theoretical value. The procedure enabled to detect a reversible impairment of respiratory and phosphorylating functions of lung mitochondria under conditions of haemorrhagic shock, which was the most distinct within the first hours after blood reinfusion. Correlation was established between dynamics of alterations in mitochondrial energy production in lung tissue within posthaemorrhagic period and structure-functional characteristics of the lung surface system.
D000818:Animals; D001804:Blood Transfusion, Autologous; D002682:Chinchilla; D008168:Lung / Q000378:metabolism*; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D010085:Oxidative Phosphorylation; D011663:Pulmonary Surfactants / Q000378:metabolism; D012771:Shock, Hemorrhagic / Q000378:metabolism* / Q000628:therapy
D011663:Pulmonary Surfactants
Okislitel'noe fosforilirovanie v mitokhondriiakh legkikh pri massivnoĭ krovopotere i vospolnenii ee autokrov'iu.