[Blockade of estradiol benzoate hyperplasia of the adenohypophysis with Deprenon and lisuride - histological findings].
Three-week administering of Estradiolbenzoate to male rats results in hyperplasia of adenohypophysis with increase of Orange G slightly positive cells and chromophobe cells, loosening of structure giving a trabecular picture, and stressed vascularization. Simultaneous administering of Ergoline compounds (Deprenon, Lisuride) rather limited the transformation. However, the differentiation of single pituitary cells due to Estradiolbenzoate remained substantially uninfluenced.
D000818:Animals; D004873:Ergolines / Q000494:pharmacology*; D004958:Estradiol / Q000494:pharmacology*; D006965:Hyperplasia; D008090:Lisuride / Q000494:pharmacology*; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000473:pathology*; D051381:Rats
D004873:Ergolines; C004278:D-6-methyl-8-ergolin-1-ylacetic acid amide tartrate; D004958:Estradiol; D008090:Lisuride
Blokáda estradiolbenzoátové hyperplazie adenohypofýzy deprenonem a lisuridem - histologický nález.