title: A general expression for sequential DNA-fluorescence histograms.
abstract: A general expression for time sequences of DNA-fluorescence histograms from flow microfluorometry is given in this paper. Such expression is given in terms of the law of DNA growth along S phase, the flux of cells into S, and the efflux out of M. Special conditions of growth (e.g. the exponential steady-state growth), and the case of blocks in S phase are also analyzed. Some simulations of the expressions obtained are presented.
mesh_terms: D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D005434:Flow Cytometry; D007399:Interphase; D008938:Mitosis; D008954:Models, Biological; D013997:Time Factors
chemical_list: D004247:DNA