[Effect of indoprofen on biliary secretion in the rat].
The activity of indoprophen on biliary secretion of rats has been investigated. Indoprophen, at a dose of 20 mg/kg induces a marked choleretic effect. It has been hypothesized that the choleretic action of indoprophen could be attributed to an inhibition of prostaglandin-synthetase and to an increase of cAMP which is the physiological factor responsible of ductal choleresis.
D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism*; D007216:Indoprofen / Q000494:pharmacology*; D008297:Male; D010666:Phenylpropionates / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D010666:Phenylpropionates; D007216:Indoprofen
Effetto dell'indoprofene sulla secrezione biliare di ratto.