[Determination of bumadizone, phenylbutazone and oxyphenbutazone in human plasma by high-performance liquid chromatography (author's transl)].
HPLC methods are described to determine bumadizone, phenylbutazone and oxyphenbutazone in human plasma. The procedure for the determination of phenylbutazone and oxyphenbutazone is based on a microphase extraction and especially suitable for routine analyses because of its simplicity and rapidity. 0.5 microgram of the compounds per milliliter plasma can easily be determined; the relative standard deviations of the methods are between 0.7 and 4.4% at therapeutic plasma concentrations.
D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D008314:Malonates / Q000097:blood*; D010113:Oxyphenbutazone / Q000097:blood*; D010653:Phenylbutazone / Q000097:blood*
D008314:Malonates; C100233:bumadizone; D010653:Phenylbutazone; D010113:Oxyphenbutazone
Uber die quantitative Bestimmung von Bumadizon, Phenylbutazon und Oxyphenbutazon aus Humanplasma mittels Hochdruckflüssigkeitschromatographie.