Plasma xanthine levels in premature infants treated for apnoea with theophylline.
Evidence is presented that oral theophylline doses of 3 mg per kg per 24 h in premature babies produces plasma levels of theophylline and caffeine of about 5 and 1-2 mg/l respectively in most subjects.
D001049:Apnea / Q000097:blood / Q000188:drug therapy*; D002110:Caffeine / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000188:drug therapy*; D007700:Kinetics; D013806:Theophylline / Q000097:blood / Q000627:therapeutic use*; D014970:Xanthines / Q000097:blood*
D014970:Xanthines; D002110:Caffeine; D013806:Theophylline