Olivocerebellar projections in control and staggerer mutant mice. An autoradiographic study.
Olivocerebellar projections were studied in normal and in staggerer mutant mice by means of autoradiographic methods following [3H]leucine injections in the inferior olivary complex. In normal mice, a sagittal banding pattern of labeled climbing fibers was apparent in the contralateral cerebellar cortex, thus confirming previous observations in rodents. In staggerer mice, olivocerebellar projections also displayed a clear sagittal zonation, thus indicating that this organization may be achieved in the mutant, in spite of pronounced abnormalities of the cerebellar cortex.
D000818:Animals; D001931:Brain Mapping; D002525:Cerebellar Cortex / Q000033:anatomy & histology*; D006824:Hybridization, Genetic; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008818:Mice, Neurologic Mutants; D009434:Neural Pathways / Q000033:anatomy & histology; D009847:Olivary Nucleus / Q000033:anatomy & histology*