title: Prognostic value of sweat-chloride levels in cystic fibrosis: a negative report.
abstract: Sweat-chloride levels at the time of diagnosis have been reviewed from 708 patients with cystic fibrosis. Sixty-one patients, shown to be non-steatorrheic, were found to have significantly lower levels than 647 patients with severe pancreatic insufficiency. Although patients who retain pancreatic function are known to have less severe pulmonary involvement and a better overall prognosis (5), we were unable to show any correlation of sweat-chloride levels at diagnosis with pulmonary function, current age or Shwachman clinical score which might be of prognostic value.
mesh_terms: D002712:Chlorides / Q000032:analysis* / Q000378:metabolism; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D013542:Sweat / Q000032:analysis* / Q000378:metabolism
chemical_list: D002712:Chlorides