Body weight and its effect on immunoreactive parathyroid hormone levels.
Immunoreactive parathyroid hormone (iPTH) levels were measured in 12 obese subjects (140-272% ideal body weight) and 10 normal lean volunteers (93-100% ideal body weight). iPTH values were not significantly different in the two groups and tubular maximum phosphate reabsorption (TmP) was comparable in lean subjects and the 4 obese patients tested. 4 obese subjects were evaluated after an average of 6.7% body weight loss, and neither iPTH levels nor TmP were affected. The data indicate that the biological effects of PTH are not enhanced in the massively obese.
D000042:Absorption; D000293:Adolescent; D000328:Adult; D001835:Body Weight; D002118:Calcium / Q000097:blood; D002648:Child; D003404:Creatinine / Q000378:metabolism; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism; D009765:Obesity / Q000097:blood* / Q000378:metabolism; D010281:Parathyroid Hormone / Q000097:blood*; D010710:Phosphates / Q000378:metabolism; D010758:Phosphorus / Q000097:blood
D010281:Parathyroid Hormone; D010710:Phosphates; D010758:Phosphorus; D003404:Creatinine; D002118:Calcium