title: Haloperidol-induced plasticity of axon terminals in rat substantia nigra.
abstract: An electron micrographic morphometric analysis of nerve endings in substantia nigra of rats repeatedly treated with haloperidol was performed. Although most parameters showed no difference, drug-treated animals exhibited a significant shift in the distribution of relative numbers of axon terminals, suggesting neuroleptic-induced axon-collateral sprouting.
mesh_terms: D000818:Animals; D001369:Axons / Q000187:drug effects; D003712:Dendrites / Q000187:drug effects; D006220:Haloperidol / Q000494:pharmacology*; D008297:Male; D008854:Microscopy, Electron; D009068:Movement / Q000187:drug effects; D009473:Neuronal Plasticity / Q000187:drug effects*; D051381:Rats; D013378:Substantia Nigra / Q000187:drug effects / Q000502:physiology*
chemical_list: D006220:Haloperidol