title: Biosynthesis of a low molecular weight collagen by rabbit growth plate cartilage organ cultures.
abstract: Analysis of [14C]-proline labeled proteins synthesized by organ cultures of rabbit growth plate cartilage slices revealed that this tissue synthesized a low molecular weight collagen in addition to Type II, 1 alpha, 2 alpha, and 3 alpha collagens. This collagen appears to be a distinct molecular species on the basis of electrophoretic mobility, hydroxyproline content and cyanogen bromide peptide mapping. In subsequent studies, a non-disulfide-bonded, higher molecular weight form of the same molecule was identified.
mesh_terms: D000818:Animals; D002356:Cartilage / Q000378:metabolism*; D003094:Collagen / Q000096:biosynthesis*; D004220:Disulfides / Q000032:analysis; D008970:Molecular Weight; D009924:Organ Culture Techniques; D010446:Peptide Fragments / Q000032:analysis; D011817:Rabbits
chemical_list: D004220:Disulfides; D010446:Peptide Fragments; D003094:Collagen