[Effect of lithium hydroxybutyrate on the serotonin content of the brain in intact rabbits and during hyperactivity of the central serotoninergic systems].
Chronic administration of lithium hydroxybutyrate (10 mg/kg) to rats reduces the content of serotonin in the caudate nucleus, suppresses the growth of its level in all the subcortical brain structures. After 5-hydroxytryptophan administration it perverses the serotonin-positive action of dorsal raphe nucleus electric stimulation.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004558:Electric Stimulation; D005260:Female; D006885:Hydroxybutyrates / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D009942:Organometallic Compounds; D011817:Rabbits; D011903:Raphe Nuclei / Q000502:physiology; D012701:Serotonin / Q000378:metabolism* / Q000494:pharmacology
D006885:Hydroxybutyrates; D009942:Organometallic Compounds; D012701:Serotonin; C022826:lithium hydroxybutyrate; D008094:Lithium
Vliianie oksibutirata litiia na soderzhanie serotonina v mozge intaktnykh krolikov i v usloviiakh giperaktivnosti tsentral'nykh serotoninergicheskikh sistem.