Correlation of false negative myocardial infarct scintigraphy with postmortem studies.
Negative myocardial infarct scintigrams with 99mtechnetium stannous pyrophosphate (99mTc-PYP) were obtained in two patients with acute massive transmural infarct. Both patients died soon after scintigraphy. Because necropsy was performed within hours after death, we were able to correlate the distribution of the tracer within the acutely infarcted tissue with the myocardial scintigram. The clinical implication is that a single myocardial scintigram may be grossly inaccurate in detecting and quantifying infarct size. The scintigraphic findings should always be correlated with the electrocardiographic and enzymatic findings in evaluating patients with possible myocardial infarct.
D000368:Aged; D001344:Autopsy; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011877:Radionuclide Imaging; D013667:Technetium; D016698:Technetium Tc 99m Pyrophosphate; D014003:Tin Polyphosphates
D014003:Tin Polyphosphates; C017742:technetium Tc 99m stannous pyrophosphate; D016698:Technetium Tc 99m Pyrophosphate; D013667:Technetium