[Use of terbutaline sulfate (Bricalyn Astra-Egyt) for betamimetic tocolysis].
The authors have undertaken controlled prospective clinical studies into Bricanyl treatment of 40 women with imminent abortion. Their conclusion has been that Bricanyl was an effective tocolytic for both intravenous and oral application. Thirty-eight cases were followed up to birth, with 30 mature infants being born plus seven premature birth (four of these immature). Abortion occurred in one case. Three foetuses were perinatally lost in the immature group. There were no side-effects which might have necessitated discontinuation of therapy. All tocolysed patients came under ECG control, and pathological changes were recorded from 17 in 31 women. Another checkup after birth revealed that all ECG findings had been restored to normal. Repeated warnings are given by the authors against application of betamimetics on an outpatient basis.
D000033:Abortion, Threatened / Q000517:prevention & control; D004341:Drug Evaluation; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D011247:Pregnancy; D011446:Prospective Studies; D013726:Terbutaline / Q000008:administration & dosage* / Q000009:adverse effects
D013726:Terbutaline
Die Anwendung von Terbutalin-Sulfat (Bricanyl ASTRA-EGYT) zur betamimetischen Tokolyse.