Association of glyoxalase I allotypes with Graves' disease and diabetes mellitus.
In view of the demonstrated linkage of glyoxalase I (GLO) with HLA, we studied the possible association of Graves' disease and juvenile diabetes with GLO allotypes. Both these diseases are known to show significant HLA associations. The distributions of the two GLO allotypes in the two disease groups were identical to those found in the control group.
D003920:Diabetes Mellitus / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D008040:Genetic Linkage; D006111:Graves Disease / Q000235:genetics / Q000276:immunology*; D006680:HLA Antigens; D006801:Humans; D007126:Immunoglobulin Allotypes; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008190:Lyases / Q000235:genetics*
D006680:HLA Antigens; D007126:Immunoglobulin Allotypes; D008190:Lyases; D007791:Lactoylglutathione Lyase