Diagnosis and treatment of pregnancy induced platelet dysfunction.
Pregnant women with either Type B EPH gestosis or gestosis alone were treated with low dose aspirin if thrombocytopenia were present (platelet counts below 75,000) or had platelet aggregation studies if their platelet counts were above 75,000. Platelet aggregation was usually decreased and aspirin therapy appeared to improve platelet counts. However, it appears that platelet abnormalities are only a secondary defect in the "gestosis" process as correction of their thrombocytopenia did not correct their hypovolemia.
D000328:Adult; D001241:Aspirin / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D005260:Female; D006801:Humans; D010952:Plasma Substitutes / Q000008:administration & dosage; D010974:Platelet Aggregation; D011225:Pre-Eclampsia / Q000097:blood; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology
D010952:Plasma Substitutes; D003907:Dexamethasone; D001241:Aspirin