Malignant hyperthermia-like reactions in three anesthetized horses.
Problems encountered during halothane anesthesia in 3 horses included increasing rectal temperature, muscle rigidity or movement during anesthesia, irregular breathing patterns, and difficulty in stabilizing blood pressure. One horse had prolonged muscle fasciculations and failure to relax after administration of succinylcholine in addition to halothane. That horse developed severe, bilateral myositis of the triceps, lumbar, and gluteal muscles. Problems encountered were similar to those caused by the disease known as malignant hyperthermia.
D000768:Anesthesia, General / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D003620:Dantrolene / Q000627:therapeutic use; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D006734:Horse Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006736:Horses; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000139:chemically induced; D013577:Syndrome / Q000662:veterinary
D003620:Dantrolene; D006221:Halothane