Neohemoglobins as blood substitutes.
The brackets in fig 5, show a cluster of cross-linked human and bovine hemoglobins whose oxygen affinity is lower than that of untreated human SFH. Also, they have a stabilized tetrameric structure, and the combination of these characteristics makes these compounds very promising as oxygen carriers in cell-free blood substitutes.
D000818:Animals; D001802:Blood Substitutes / Q000494:pharmacology*; D002417:Cattle; D003432:Cross-Linking Reagents; D006418:Heme / Q000031:analogs & derivatives* / Q000494:pharmacology; D006454:Hemoglobins / Q000494:pharmacology*; D006801:Humans; D010100:Oxygen / Q000097:blood; D013329:Structure-Activity Relationship
D001802:Blood Substitutes; D003432:Cross-Linking Reagents; D006454:Hemoglobins; D006418:Heme; D010100:Oxygen