title: Milk 99Tcm-EHIDA test for enterogastric bile reflux.
abstract: The study and clinical assessment of enterogastric bile reflux has been restricted for want of a simple non-invasive test for its detection and quantification. This paper describes such a test in which biliary excretion scintigraphy has been combined and a mild meal provocation. Two of 10 healthy volunteers studied showed probable reflux of approximately 5 per cent of total initial abdominal field activity. Among 73 patients studied, 37 patients showed definite reflux of up to 47 per cent. Reflux occurred in 19 of 22 post-gastric surgery patients and in 7 of 22 patients with peptic ulcer disease, gastritis or gastro-oesophageal reflux. None of 7 patients with 'non-specific' abdominal pain showed any reflux, but 11 of 22 patients with gallstone disease or previous cholecystectomy showed reflux of up to 35 per cent, including 9 of 11 patients with loss of gallbladder reservoir function.
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001655:Bile Reflux / Q000000981:diagnostic imaging*; D001660:Biliary Tract Diseases / Q000000981:diagnostic imaging*; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D008892:Milk; D011877:Radionuclide Imaging; D013667:Technetium; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid
chemical_list: D007098:Imino Acids; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; D013667:Technetium