title: Effects of amiprophosmethyl on massive and limited calcium loading of maize mitochondria.
abstract: In maize mitochondria the effect of the herbicide amiprophosmethyl was studied on massive and limited Ca2+-loading and on mitochondrial energy transduction. Under massive Ca2+-loading conditions amiprophosmethyl inhibited the Ca2+ transport system directly without a significant effect on the respiratory chain, the membrane potential or Ca2+ efflux. Under limited Ca2+-loading conditions an increased Ca2+ efflux was noted, which could be partially responsible for the inhibition of the net Ca2+ accumulation.
mesh_terms: D002118:Calcium / Q000378:metabolism* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004735:Energy Transfer / Q000187:drug effects; D008564:Membrane Potentials / Q000187:drug effects; D008928:Mitochondria / Q000378:metabolism*; D009578:Nitrobenzenes; D009946:Organothiophosphorus Compounds / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D010944:Plants / Q000187:drug effects / Q000378:metabolism*; D003313:Zea mays / Q000187:drug effects / Q000378:metabolism
chemical_list: D009578:Nitrobenzenes; D009946:Organothiophosphorus Compounds; C017823:amiprophos methyl; D002118:Calcium