HLA in familial Hodgkin's disease.
We report HLA genotypes in four familial cases of Hodgkin's disease (HD), Nodular Sclerosis (NS) histological subtype, where all patients showed B18 antigen. This finding, although statistically not supported, confirms the possible correlation between HD and B18 antigen which carries a high relative risk in international data.
D000293:Adolescent; D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D015235:HLA-B Antigens; D059911:HLA-B18 Antigen; D006689:Hodgkin Disease / Q000235:genetics / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens; D015235:HLA-B Antigens; D059911:HLA-B18 Antigen