title: [Lipid composition of rat liver microsomes under various experimental conditions].
abstract: Cholesterol and phospholipid content, and phospholipid composition (sphingomyelin, phosphatidylcholine, phosphatidylserine, phosphatidylinositol, phosphatidylethaolamine) were assayed in rat liver microsomes during regeneration, foetal development and pregnancy. Cholesterol was assayed using Liebermann-Buchard reagent; the phospholipid extract was separated by thin-layer chromatography. While in pregnancy no changes were observed, during foetal development and liver regeneration there was a significative decrease of cholesterol/phospholipid ratio, and of phosphatidylcholine content. Moreover, in developing liver microsomes, there is also a significative increase of sphingomyelin and phosphatidylserine + phosphatidylinositol.
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000032:analysis*; D008862:Microsomes, Liver / Q000032:analysis*; D010743:Phospholipids / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010743:Phospholipids; D002784:Cholesterol
vernacular_title: Composizione lipidica dei microsomi di fegato di ratto in diverse condizioni sperimentali.