Detection of abscesses and lymphosarcoma with 111In-deferoxamine mesylate.
Indium-111 deferoxamine was used to delineate induced abscesses or different ages in a baboon, and lymph nodes in a case of canine spontaneous lymphosarcoma, by means of gamma-scintigraphy. Positive results were obtained already 1 hr after administration of the scanning agent, and the lesion-to-background ratio improved progressively with time. The tissue distribution of the radiopharmaceutical was determined in rats, and showed a relatively high isotope retention in the kidneys.
D000038:Abscess / Q000000981:diagnostic imaging*; D000818:Animals; D004285:Dogs; D007204:Indium; D007866:Leg / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging*; D008297:Male; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging*; D010215:Papio; D011868:Radioisotopes; D011877:Radionuclide Imaging
D011868:Radioisotopes; D007204:Indium