title: Controlled tests of ivermectin against migrating Strongylus vulgaris in ponies.
abstract: Twelve pony foals were reared worm-free and inoculated with Strongylus vulgaris. On day 7 after inoculation, 6 ponies were given ivermectin IM at a dose of 200 micrograms/kg of body weight and on day 28 were necropsied. Ivermectin was effective in eliminating early 4th-stage S vulgaris larvae and reducing clinical signs associated with acute arteritis. After administrative ivermectin was effective against early 4th-stage Strongylus vulgaris larvae in ponies when administered at 100, 300, or 800 micrograms/kg of body weight. The purpose of the present study was to report on a more extensive trial, using a single dosage of ivermectin.
mesh_terms: D000818:Animals; D006736:Horses; D007559:Ivermectin; D007783:Lactones / Q000627:therapeutic use*; D013319:Strongyle Infections, Equine / Q000188:drug therapy*
chemical_list: D007783:Lactones; D007559:Ivermectin