Diabetic neuroarthropathy (Charcot's joint).
The pathologic aspects of an uncommon complication of diabetes mellitus, destructive arthropathy (Charcot's joint), were studied. The peripheral nerve demyelination resulting in clinically demonstrable deficits in perception of pain and vibration and in reflexes in the lower extremities reinforces the neurogenic role in this complication.
D000843:Ankle Joint / Q000473:pathology; D001177:Arthropathy, Neurogenic / Q000473:pathology*; D002358:Cartilage, Articular / Q000473:pathology; D003929:Diabetic Neuropathies / Q000473:pathology*; D005533:Foot Dermatoses / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology