[Hereditary angioedema. A clinical and immunologic contribution based on our 8 clinical cases under long-term treatment with androgens].
The literature on hereditary angioedema is reviewed and the case histories of 5 women and 3 men are reported. Special importance is attached to the results of therapy over 222 months of treatment with danazol and 40 months with stanozolol. The effects of androgen therapy on complement factor C4 and on C1-inhibitor are described.
D000328:Adult; D000799:Angioedema / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D003174:Complement C1 Inactivator Proteins / Q000097:blood; D003181:Complement C4 / Q000378:metabolism; D003613:Danazol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013197:Stanozolol / Q000627:therapeutic use
D003174:Complement C1 Inactivator Proteins; D003181:Complement C4; D013197:Stanozolol; D003613:Danazol
Hereditäres Angioödem. Ein klinischer und immunologischer Beitrag anhand von 8 eigenen Fällen unter Langzeitbehandlung mit Androgenen.