title: Plant anticancer agents. XXIV. Alkaloid constituents of Simaba multiflora.
abstract: Two new cytotoxic canthin-6-ones, 10-methoxycanthin-6-one (1) and 10-hydroxycanthin-6-one (2) were isolated from the wood of Simaba multiflora (Simaroubaceae). Three canthin-2,6-dione (3), 3-methoxycanthin-2,6-dione (4) and canthin-2,6-dione (5), as well as scopoletin (7) and the novel coumarino-lignan cleomiscosin A (6) were also obtained.
mesh_terms: D000107:Acetylation; D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D051379:Mice
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic