Overwhelming postsplenectomy infection (OPSI): the clinical syndrome.
Critical examination of the infectious risk following splenectomy raises questions about several widely held notions. True hazard of OPSI is difficult to quantify and probably underestimated, susceptibility is life-long, questionably altered by splenosis, and persists despite penicillin prophylaxis and vaccination against common pneumococcal serotypes.
D003937:Diagnosis, Differential; D006801:Humans; D011008:Pneumococcal Infections / Q000175:diagnosis*; D011183:Postoperative Complications; D012306:Risk; D013156:Splenectomy / Q000009:adverse effects*; D013577:Syndrome