[Mitochondrial cardiomyopathy with a high degree of heart muscle hypertrophy].
Because of cardiomyopathy with concomitant cardiac hypertrophy, a 21 month-old girl died 7 days following operative closure of a cleft palate. The cardiomyopathy was due to an excessive increase of enlarged and abnormally structured mitochondria. Similar mitochondrial change were found in the skeletal muscles (Mitochondrial Myopathy).
D002312:Cardiomyopathy, Hypertrophic / Q000473:pathology*; D002972:Cleft Palate / Q000601:surgery; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000473:pathology; D006346:Heart Septum / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D007223:Infant; D008929:Mitochondria, Heart / Q000648:ultrastructure*; D009206:Myocardium / Q000473:pathology; D011183:Postoperative Complications / Q000473:pathology
Mitochondriale Cardiomyopathie mit hochgradiger Herzmuskelhypertrophie.