title: [Intestinal schistosomiasis. Early hepatic involvement with portal hypertension: study of 5 cases].
abstract: Pathological and hemodynamic investigations were performed in 5 canadian patients who had been infected by Schistosoma mansoni four months before in Martinique. Mononuclear cell infiltration of portal tracts was disclosed in all 5 patients; it was associated with eosinophilic infiltration in 3, hepatocellular necrosis in 3, granulomas in 2 and fibrosis in 2. Presinusoidal portal hypertension was demonstrated in 4 out of the 5 patients. These observations suggest that histological changes are constant at this stage after infestation by S. mansoni and could be responsible for the early development of portal hypertension which is classically a late feature of the disease.
mesh_terms: D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology*; D007411:Intestinal Diseases, Parasitic / Q000150:complications*; D008109:Liver Diseases, Parasitic / Q000209:etiology*; D008297:Male; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000150:complications*; D013997:Time Factors
vernacular_title: Schistosomiase intestinale. Précocité de l'atteinte hépatique avec hypertension portale: étude de cinq cas.