The effect of diet on intermediary metabolite concentrations in Type 2 (non-insulin-dependent) diabetes mellitus.
The metabolic response to a standard meal was studied in six Type 2 (non-insulin-dependent) diabetic patients at diagnosis and following 4-6 weeks of dietary treatment. The fall in blood glucose concentration following treatment was accompanied by significant reductions in circulating concentrations of lactate, pyruvate, alanine and glycerol. Blood 3-hydroxybutyrate concentrations also fell with treatment.
D020155:3-Hydroxybutyric Acid; D000328:Adult; D000368:Aged; D000409:Alanine / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood / Q000178:diet therapy*; D005260:Female; D005990:Glycerol / Q000097:blood; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D011773:Pyruvates / Q000097:blood; D019289:Pyruvic Acid; D013997:Time Factors
D006885:Hydroxybutyrates; D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; D000409:Alanine; D005990:Glycerol; D020155:3-Hydroxybutyric Acid