title: The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes.
abstract: The chromosomal distribution of murine genes expressed during differentiation of skeletal muscle cells was determined by Southern blot analysis of DNA from mouse-Chinese hamster hybrid cell lines containing incomplete subsets of mouse chromosomes. All detectable myosin heavy chain genes are located on chromosome 11. The gene for the myosin light chain 2 is located on chromosome 7. The skeletal muscle alpha-actin gene and several other actin genes, or pseudogenes, are located on chromosome 3. Additional actin DNA sequences are distributed on other mouse chromosomes.
mesh_terms: D000199:Actins / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes / Q000502:physiology*; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000032:analysis; D005333:Fetus; D005796:Genes; D006822:Hybrid Cells / Q000378:metabolism; D046911:Macromolecular Substances; D051379:Mice; D008807:Mice, Inbred BALB C; D008970:Molecular Weight; D009132:Muscles / Q000378:metabolism*; D009218:Myosins / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D010957:Plasmids
chemical_list: D000199:Actins; D046911:Macromolecular Substances; D004247:DNA; D009218:Myosins