title: Inheritance and expression of a sex-linked enzyme in the frog, Rana clamitans.
abstract: The pattern of inheritance indicates that the gene for aconitase-1 is sex linked in the frog. Rana clamitans, and that the male is the heterogametic sex. Unlike mammals, both male and female frogs carry and express two alleles for this sex-linked gene. Therefore, the sex chromosomes in these frogs and probably others behave like an autosomal pair, with one homologue carrying a male-determining element.
mesh_terms: D000154:Aconitate Hydratase / Q000235:genetics*; D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage; D008297:Male; D011898:Ranidae / Q000235:genetics*; D012730:Sex Chromosomes
chemical_list: D000154:Aconitate Hydratase