title: Urinary androgen metabolites and recurrence rates in early breast cancer.
abstract: Androsterone and aetiocholanolone were measured in urine specimens obtained from 218 women with early breast cancer. Patients who excreted less than the median amount of these steroids had a significantly higher recurrence rate (P less than 0.005) than patients excreting more than the median value. The relationship between androgen excretion and recurrence is stronger in pre-menopausal women that in the post-menopausal group. The androgen assays are still associated with recurrence rates when patients are stratified by pathological stage, but no clear relationship was found with histological grade.
mesh_terms: D000738:Androsterone / Q000652:urine*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery / Q000652:urine*; D005043:Etiocholanolone / Q000652:urine*; D005260:Female; D006801:Humans; D008408:Mastectomy; D008593:Menopause; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging
chemical_list: D005043:Etiocholanolone; D000738:Androsterone