Experimental investigations in hamsters and rabbits with DNA extracted from human uterine tumors.
Experimental inoculation of a DNA preparation extracted from a fragment of non-irradiated human uterine cervix carcinoma was followed by the appearance of neoplasia in four hamsters and of lymphosarcoma in one rabbit. Similar DNA preparations obtained from three cases of irradiated human uterine cervix carcinoma and from a human uterine fibroma proved to have no biological activity.
D000230:Adenocarcinoma; D000818:Animals; D002822:Choriocarcinoma; D006224:Cricetinae; D004273:DNA, Neoplasm; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D009374:Neoplasms, Experimental; D011247:Pregnancy; D011817:Rabbits; D002583:Uterine Cervical Neoplasms; D014594:Uterine Neoplasms
D004273:DNA, Neoplasm