An audit of chloramphenicol use in a large community hospital.
In a large community hospital during a six-month period, 238 of 19,670 hospitalized patients (1.2%) received chloramphenicol. The drug was administered exclusively by the intravenous route in 98% of these patients. In 78% of the patients, chloramphenicol was used for an appropriate indication, whereas in 22%, its use was inappropriate. Serious toxic effects and unexpected clinical failures were not observed.
D001424:Bacterial Infections / Q000188:drug therapy / Q000401:mortality; D002701:Chloramphenicol / Q000008:administration & dosage / Q000627:therapeutic use*; D003133:Commission on Professional and Hospital Activities; D003237:Connecticut; D004363:Drug Utilization / Q000639:trends*; D006746:Hospital Bed Capacity, 500 and over; D006764:Hospitals, Community; D006801:Humans; D014481:United States
D002701:Chloramphenicol