Inability of the NADH-cytochrome b5 reductase system to initiate heme degradation yielding biliverdin IX alpha from the oxygenated form of heme . heme oxygenase complex.
D000818:Animals; D001663:Bilirubin / Q000031:analogs & derivatives; D001664:Biliverdine; D001665:Binding Sites; D003579:Cytochrome Reductases / Q000378:metabolism*; D042966:Cytochrome-B(5) Reductase; D006418:Heme; D006419:Heme Oxygenase (Decyclizing); D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases; D011485:Protein Binding; D013053:Spectrophotometry; D013154:Spleen / Q000201:enzymology; D013552:Swine
D006418:Heme; D006899:Mixed Function Oxygenases; D006419:Heme Oxygenase (Decyclizing); D003579:Cytochrome Reductases; D042966:Cytochrome-B(5) Reductase; D001664:Biliverdine; D001663:Bilirubin