Production of 6-oxo-prostaglandin F1 alpha, PGF2 alpha and PGE2 by sheep uterine tissue.
Incubation in vitro of sheep uterine tissue revealed that although both caruncular and non-carunuclar endometrium can synthesize appreciabel quantities of PGF2 alpha, PGE2 and 6-oxo-PGF2 alpha, the myometrium synthesizes predominantly 6-oxo-PGF1 alpha. Non-caruncular endometrium contained more 6-oxo-PGF1 alpha than either the myometrium or the caruncles, while myometrial tissue possessed less PGF2 alpha than either caruncular or non-caruncular endometrium.
D015121:6-Ketoprostaglandin F1 alpha; D000818:Animals; D004717:Endometrium / Q000378:metabolism; D005260:Female; D066298:In Vitro Techniques; D009215:Myometrium / Q000378:metabolism; D011458:Prostaglandins E / Q000096:biosynthesis*; D011460:Prostaglandins F / Q000096:biosynthesis* / Q000378:metabolism*; D012756:Sheep / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*
D011458:Prostaglandins E; D011460:Prostaglandins F; D015121:6-Ketoprostaglandin F1 alpha