Serum antibodies in Campylobacter enteritis.
A solid-phase enzyme immunoassay method for the measurement of total and class-specific serum antibodies to Campylobacter jejuni was developed. The test was found to be both sensitive and specific. Immunoglobulin M, G, and A antibodies were detected in about 90% of sera collected from patients recovering from Campylobacter enteritis, with the pattern of appearance and decline of these antibodies conforming to that usually seen in an acute infection. A poor antibody response was noted in patients with intermittent or prolonged enteritis. The clinical implications and diagnostic value of this test are discussed.
D000907:Antibodies, Bacterial / Q000032:analysis*; D000918:Antibody Specificity; D002169:Campylobacter Infections / Q000276:immunology*; D002168:Campylobacter fetus / Q000276:immunology; D004751:Enteritis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*
D000907:Antibodies, Bacterial; D007136:Immunoglobulins