[Allergy to Hymenoptera venom. The value of allergen-specific IgG in therapy].
Between October, 1979 and December, 1982, Reless-hymenoptera venom was given to 70 patients to hyposensitize them. In 23 patients who during this treatment were subjected to a provocation test with a bee or wasp sting no systemic reaction occurred. At the time of the provocation test these patients had a wide scatter of antigen-specific IgG serum levels, between 34 and greater than 1000 U/ml. The IgG level was dose- and age-dependent. Demonstration of specific IgG levels alone does not make it possible to assess the success of the hyposensitization regimen.
D000918:Antibody Specificity; D001180:Arthropod Venoms / Q000276:immunology*; D001514:Bee Venoms / Q000008:administration & dosage; D003888:Desensitization, Immunologic / Q000379:methods*; D004306:Dose-Response Relationship, Immunologic; D006801:Humans; D006927:Hymenoptera; D006967:Hypersensitivity / Q000276:immunology / Q000628:therapy*; D007074:Immunoglobulin G / Q000032:analysis*; D011852:Radioallergosorbent Test; D013997:Time Factors; D014862:Wasp Venoms / Q000008:administration & dosage
D001180:Arthropod Venoms; D001514:Bee Venoms; D007074:Immunoglobulin G; D014862:Wasp Venoms
Hymenopterengift-Allergie. Stellenwert des allergenspezifischen IgG bei der Therapie.