ts P1 and P3 genes are responsible for satisfactory level of attenuation of ts-1A2 recombinants bearing H1N1 or H3N2 surface antigens of influenza A virus.
D000328:Adult; D004591:Electrophoresis, Polyacrylamide Gel; D005814:Genes, Viral; D006389:Hemagglutinins, Viral / Q000235:genetics; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000235:genetics*; D007252:Influenza Vaccines / Q000302:isolation & purification*; D009154:Mutation; D009439:Neuraminidase / Q000235:genetics; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics; D011995:Recombination, Genetic; D013696:Temperature; D014613:Vaccines, Attenuated / Q000302:isolation & purification*; D014764:Viral Proteins / Q000235:genetics; D014774:Virulence
D006389:Hemagglutinins, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated; D014764:Viral Proteins; D012324:RNA-Dependent RNA Polymerase; D009439:Neuraminidase