Quantitative determination of praziquantel in serum by high-performance liquid chromatography.
A simple method for the quantitation of praziquantel by high-performance liquid chromatography is described. This method has a lower limit of sensitivity of 2.5 ng of drug per ml of human serum and a relative standard deviation of 2.6% at concentrations of 5 ng/ml.
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D005260:Female; D007546:Isoquinolines / Q000097:blood*; D008297:Male; D051379:Mice; D008832:Microchemistry; D011223:Praziquantel / Q000097:blood*; D013048:Specimen Handling; D013056:Spectrophotometry, Ultraviolet
D007546:Isoquinolines; D011223:Praziquantel