Efficacy of Ivermectin against Dirofilaria immitis larvae in dogs 31, 60, and 90 days after injection.
Ivermectin, given as a single oral dose of 0.05 mg/kg, prevented the maturation of Dirofilaria immitis in dogs if given at 31 or 60 days after infection. When treatment was delayed 90 days after injection, maturation of worms occurred in 3 of 5 dogs.
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004184:Dirofilariasis / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D007559:Ivermectin; D007783:Lactones / Q000627:therapeutic use*; D013997:Time Factors
D000871:Anthelmintics; D007783:Lactones; D007559:Ivermectin