title: Opsonic effect of rainbow trout (Salmo gairdneri) antibody on phagocytosis of Yersinia ruckeri by trout leukocytes.
abstract: Partly purified peripheral blood leukocytes from normal rainbow trout (Salmo gairdneri) were used to study the influence of specific antibody on phagocytic uptake and intracellular killing of Yersinia ruckeri, a bacterial pathogen of trout. Specific antibody exerted a significant opsonic effect on the rate of phagocytic ingestion of the bacteria but did not affect the rate of intracellular killing. The results are discussed with reference to the current understanding of fish antibody function and phagocytosis by fish leukocytes.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial; D001770:Blood Bactericidal Activity; D005393:Fish Diseases / Q000276:immunology; D007962:Leukocytes / Q000276:immunology; D009895:Opsonin Proteins; D010587:Phagocytosis; D012487:Salmonidae / Q000276:immunology*; D014337:Trout / Q000276:immunology*; D015009:Yersinia Infections / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D009895:Opsonin Proteins