title: Low doses of 2,4,5-trichlorophenoxyacetic acid are behaviorally teratogenic to rats.
abstract: Pre-natal exposure of rats to 2,4,5-T has long-term effects on behavior. A test for novelty responding detects abnormalities after exposure to a single dose as low as 6 mg/kg on day 8 of gestation. This is well below doses reported to be morphologically teratogenic, and raises concern for human exposure.
mesh_terms: D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000633:toxicity*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D005106:Exploratory Behavior / Q000187:drug effects; D005260:Female; D006801:Humans; D009043:Motor Activity / Q000187:drug effects; D011247:Pregnancy; D051381:Rats; D013723:Teratogens
chemical_list: D013723:Teratogens; D015085:2,4,5-Trichlorophenoxyacetic Acid