A previously described serum protein polymorphism in the rat identified as Gc ('vitamin D-binding protein').
The previously published serum protein polymorphisms G1-1 (Moutier, Toyama & Charrier, 1973) and 'tf' (Bender & Günther, 1978) are identical and represent genetic variation at the locus of the vitamin D-binding a-globulin, also known a Gc or group-specific component. The identity was established by comparative protein staining, by functional tests with 14C-vitamin D3, by immunological studies with specific anti-Gc sera and by the strain distribution patterns. The Gc polymorphism in the rat may initiate interesting physiological and genetical studies.
D000818:Animals; D001798:Blood Proteins / Q000235:genetics*; D002352:Carrier Proteins / Q000235:genetics*; D007525:Isoelectric Focusing; D010641:Phenotype; D011110:Polymorphism, Genetic; D051381:Rats; D013045:Species Specificity; D014807:Vitamin D / Q000097:blood* / Q000235:genetics*; D014809:Vitamin D-Binding Protein
D001798:Blood Proteins; D002352:Carrier Proteins; D014809:Vitamin D-Binding Protein; D014807:Vitamin D