A deletion of heterochromatin only of the Y chromosome in an azoospermic male.
A patient with a deletion of the distal portion of the long arm (q21) of chromosome Y is described clinically and cytogenetically. The proband has a normal male habitus but with azoospermia. The proband was investigated because of infertility. Male relatives were also investigated cytogenetically. The deleted Y chromosome was measured and compared with the normal Y of male family members. The results suggest that no Y euchromatin was lost.
D000328:Adult; D002871:Chromosome Banding; D002872:Chromosome Deletion; D006570:Heterochromatin; D006801:Humans; D007621:Karyotyping; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D012730:Sex Chromosomes; D014998:Y Chromosome
D006570:Heterochromatin