title: Permanent magnetic fields: influence on oxygen-substrate interactions and possible mechanisms of several biomagnetic effects.
abstract: An account is given of the "oxygen theory" of biomagnetic effects, whereby molecular oxygen is the primary, elementary, and fundamental material affected by the influence of a permanent magnetic field (PMF). The ability of a PMF to alter inductively the motion of paramagnetic O2 dissolved in a fluid, and to uncouple it from other substances which participate in oxidative processes leads, first of all, to a disturbance of O2 transport and to a disturbance of cellular bioenergetic processes. A series of biomagnetic effects are explainable on the basis of the suggested mechanism. Experimental data regarding changes in pO2 in tumor tissue under the influence of a PMF, and data concerning the inhibition of growth of reinoculated tumors (Pliss' lymphosarcoma and RS-1) under the combined influence of PMF and hypothermia, are given as indirect support of the oxygen mechanism of PMF effects and the oxygen-peroxide mechanism of carcinogenesis.
mesh_terms: D000818:Animals; D002455:Cell Division; D003080:Cold Temperature; D008228:Lymphoma, Non-Hodgkin / Q000503:physiopathology; D008280:Magnetics; D010101:Oxygen Consumption; D051381:Rats; D012513:Sarcoma, Experimental / Q000503:physiopathology