Effects of 1.25 dihydroxyvitamin D3 on calcium uptake, into rat intestine after chronic oral cadmium administration.
Calcium influx into rat intestine was investigated, in vitro, after cadmium chronic oral exposure. In active calcium transport, pretreatment by 1.25 dihydroxyvitamin D3 prevents the effect of cadmium on the maximal influx value Jm and leads to an increase of the half-saturation constant Kt.
D000818:Animals; D002105:Cadmium Poisoning / Q000378:metabolism*; D002117:Calcitriol; D002118:Calcium / Q000378:metabolism*; D004100:Dihydroxycholecalciferols / Q000494:pharmacology*; D004386:Duodenum / Q000187:drug effects / Q000378:metabolism; D005260:Female; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D007408:Intestinal Absorption / Q000187:drug effects*; D007700:Kinetics; D051381:Rats
D004100:Dihydroxycholecalciferols; D006887:Hydroxycholecalciferols; D002117:Calcitriol; D002118:Calcium