Unconjugated pteridines in human milk.
Defective de novo synthesis of tetrahydrobiopterin (BH4) has been reported as being responsible for neonatal hyperphenylalaninemia. The presence of BH4 and its derivatives in human milk is confirmed but the vitamin-like effectiveness of the BH4 supplied by human milk appeared doubtful.
D000818:Animals; D001708:Biopterins / Q000031:analogs & derivatives / Q000378:metabolism*; D004355:Drug Stability; D005260:Female; D006801:Humans; D008892:Milk / Q000378:metabolism*; D011621:Pteridines / Q000378:metabolism*
D011621:Pteridines; D001708:Biopterins; C003402:sapropterin