[Effect of the acetylcholine system on the pathogenesis of pulmonary complications during the postshock period].
In the course of the postshock period the experimental animals show changes of two types both in acetylcholine metabolism and pulmonary histophysiology. Comparison of the evidence obtained revealed a relationship between these changes, thereby promoting purposeful therapy of pulmonary complications by means of propionylcholinesterase. Administration of the preparation before and after injury improved acetylcholine metabolism, favoured the recovery of the respiratory system function, as well as an increase in the life span and decrease in lethality of the experimental animals.
D000109:Acetylcholine / Q000032:analysis*; D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D002802:Cholinesterases / Q000627:therapeutic use*; D008168:Lung / Q000032:analysis / Q000201:enzymology / Q000473:pathology; D008297:Male; D008526:Medulla Oblongata / Q000032:analysis / Q000201:enzymology; D011663:Pulmonary Surfactants / Q000032:analysis*; D051381:Rats; D012128:Respiratory Distress Syndrome / Q000517:prevention & control*; D012774:Shock, Traumatic / Q000188:drug therapy* / Q000473:pathology
D011663:Pulmonary Surfactants; C025181:propionylcholinesterase; D000110:Acetylcholinesterase; D002802:Cholinesterases; D000109:Acetylcholine
Vliianie sistemy atsetilkholina na patogenez legochnykh oslozhneniĭ v postshokovom periode.