[Effect of sex hormones on the cold resistance of rats in chronic alcohol intoxication].
Testosterone effect on the male rat resistance to the transitory moderate and prolonged acute action of cold was studied as compared with that of estrogens estradiol benzoate and progesterone in experiments on castrated animals with habitual alcohol dependence. It was shown that the resistance of the castrated made rats to the prolonged acute cold effect sharply decreases under estrogen action, whereas testosterone exerts a protective effect under the same conditions, enlarging the period of non-contagiosity to infections, produced by an excessive cooling.
D000437:Alcoholism / Q000401:mortality / Q000503:physiopathology*; D000818:Animals; D002369:Castration; D003080:Cold Temperature / Q000009:adverse effects*; D004958:Estradiol / Q000494:pharmacology*; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D008297:Male; D011374:Progesterone / Q000494:pharmacology*; D051381:Rats; D013739:Testosterone / Q000494:pharmacology*; D013997:Time Factors
D013739:Testosterone; D011374:Progesterone; D004958:Estradiol
Vliianie polovykh gormonov na ustoĭchivost' k kholodu krys s khronicheskoĭ alkogol'noĭ intoksikatsieĭ.