title: Asthma due to Central American walnut (Juglans olanchana) dust.
abstract: The purpose of our study was to describe a case of asthma due to Central American walnut (Juglans olanchana) dust and to ascertain whether an IgE antibody mechanism was implicated. The subject was a 48-year-old man who developed asthma following exposure to Central American walnut dust. Although intradermal testing with an aqueous extract of walnut dust produced no response, inhalation challenge with the extract produced significant bronchoconstriction. Another asthmatic person exposed to the wood dust had a positive skin test, but did not respond to the bronchial challenge. A direct radioallergosorbent test (RAST) on both subjects showed no evidence of serum IgE antibodies to Central American walnut dust. Consequently, the mechanism responsible for the sensitivity to the walnut dust remains unknown.
mesh_terms: D001249:Asthma / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D001985:Bronchial Provocation Tests; D004391:Dust / Q000009:adverse effects*; D005541:Forced Expiratory Volume; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009754:Nuts / Q000009:adverse effects*; D012882:Skin Tests
chemical_list: D004391:Dust; D007073:Immunoglobulin E