Incorporation of dipalmitoyl phosphatidycholine into human plasma low density lipoproteins: effects on composition and structure.
Bovine liver phosphatidylcholine exchange protein was used to transfer di[14C]palmitoyl phosphatidylcholine from sonicated vesicles to human plasma low density lipoproteins (LDL). The incorporation of di[14C]-palmitoyl phosphatidylcholine into LDL was associated with an increased percentage of total phospholipid and increased lipid rigidity as shown by an increase in the fluorescence polarization of 12-(9-anthroyloxy)-stearic acid and 1,6-diphenyl-1,3,5-hexatriene.
D000818:Animals; D002417:Cattle; D006801:Humans; D008075:Lipoproteins, HDL / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008079:Lipoproteins, VLDL / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011663:Pulmonary Surfactants / Q000378:metabolism*; D013329:Structure-Activity Relationship
D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D011663:Pulmonary Surfactants