Cell kinetics of early gestation mouse uterus.
After pulse labelling with [3H]thymidine, the labelling indices of luminal epithelial, glandular epithelial, vascular endothelial and stromal cells of the mouse uterus were determined from day 0 to 4 of gestation. First changes in the cell kinetics of endometrial cells after conception was a high proliferation rate in luminal and glandular epithelial cells on days 1 and 2 of gestation. On day 3, these cell types ceased proliferation. Simultaneously, increased proliferation activity of vascular endothelial cells was observed. The cell kinetics at the time of implantation (day 4 of gestation) were characterized by high proliferation rates of stromal and vascular endothelial cells. Proliferation activities of luminal and glandular epithelial cells were not seen at this stage.
D000818:Animals; D002453:Cell Cycle; D002455:Cell Division; D004717:Endometrium / Q000166:cytology; D004727:Endothelium / Q000166:cytology; D004847:Epithelial Cells; D005260:Female; D005865:Gestational Age; D007700:Kinetics; D051379:Mice; D011247:Pregnancy; D011270:Pregnancy, Animal; D014599:Uterus / Q000166:cytology*