High pressure liquid chromatographic determination of oxazepam dosage forms: collaborative study.
A reverse phase high pressure liquid chromatographic method for the determination of oxazepam in tablets and capsules was collaboratively studied by 9 laboratories. Collaborators were supplied with 6 samples that included synthetic and commercial formulations. Tablet and capsule composites are diluted with methanol and filtered. Oxazepam is determined at 254 nm by using a C18 column. Mean recoveries of oxazepam from synthetic tablet and capsule formulations were 97.2 and 99.0%, respectively. Mean coefficients of variation for tablets and capsules ranged from 1.85 to 2.86%. The method has been adopted official first action.
D002214:Capsules / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D010076:Oxazepam / Q000032:analysis*; D013607:Tablets / Q000032:analysis
D002214:Capsules; D013607:Tablets; D010076:Oxazepam