title: [Changes in the oxidation-reduction system of glutathione--glutathione reductase [NAD(P). H] in the blood and tissues of white rats exposed to high and low temperatures].
abstract: The content of different forms of glutathione and the NADPH-dependent glutathione reductasa activity in blood, brain, liver and sceletal muscle of the white rats exposed to low and high temperatures have been investigated. It was shown that in general cooling of animals the amount of glutathione in blood, brain and liver increases, the glutathione reductasa [NAD(P)H] activity decreases. Under super-heating conditions concentration of all forms of glutathione in blood and tissues and the glutathione reductasa activity reduce. Data obtained permitted to assume the considerable role of the changes of the glutathione-glutathione reductasa system state in the realization of temperature factors action.
mesh_terms: D000818:Animals; D003080:Cold Temperature; D005260:Female; D005978:Glutathione / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism*; D006358:Hot Temperature; D008297:Male; D009249:NADP / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats; D013696:Temperature; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D009249:NADP; D005980:Glutathione Reductase; D005978:Glutathione
vernacular_title: Izmenenie sostoianiia okislitel'no-vosstanovitel'noĭ sistemy glutation-glutationreduktazy[NAD(P). H] v krovi i tkaniakh belykh krys pri deĭstvii vysokoĭ i nizkoĭ temperature.