title: Affected sib pair method for searching major gene in multifactorial disease.
mesh_terms: D000483:Alleles; D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D006111:Graves Disease / Q000453:epidemiology / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D008297:Male; D008957:Models, Genetic; D011336:Probability
chemical_list: D006680:HLA Antigens