The effect of occlusive dressings on collagen synthesis and re-epithelialization in superficial wounds.
The effects on superficial wounds in domestic pigs of (1) two different occlusive dressings, (2) non-occlusive wet to dry gauze dressings, and (3) air exposure were compared. Collagen synthesis and re-epithelialization were increased in the wounds treated with occlusive dressings. Re-epithelialization was increased beneath both the oxygen-impermeable and the oxygen-permeable dressing. When they were removed the wet to dry gauze dressing and one of the occlusive dressings often damaged the new epidermis.
D000269:Adhesives; D000388:Air; D000818:Animals; D003094:Collagen / Q000096:biosynthesis*; D009779:Occlusive Dressings; D011140:Polyurethanes; D012867:Skin / Q000293:injuries*; D013552:Swine; D014945:Wound Healing
D000269:Adhesives; C027324:Opsiture; D011140:Polyurethanes; D003094:Collagen