[In vitro study of the action of isaxonine on the growth of rat spinal cord neurons (author's transl)].
Dissociated spinal cord cells were cultured in appropriate culture medium. In these conditions the cell bodies tended to emit neurites and to interconnect. Grown with isaxonine, spinal cord neurons form larger aggregates, neurites number is higher, connection between cellular groups is more larger, and branching of neurites is more distal. Future research will try to verify the assumption of an increase in neuromuscular contacts under the influence of isaxonine.
D000818:Animals; D002478:Cells, Cultured; D066298:In Vitro Techniques; D009474:Neurons / Q000166:cytology / Q000187:drug effects*; D011743:Pyrimidines / Q000494:pharmacology*; D051381:Rats; D013116:Spinal Cord / Q000166:cytology
D011743:Pyrimidines; C020375:isaxonine
Etude in vitro de l'action de l'isaxonine sur la croissance des neurones de la moelle épinière de rat.