Crystallization and preliminary X-ray diffraction studies of methemoglobin Bart's.
Methemoglobin Bart's (gamma 4) purified from the blood of an alpha thalassemic neonate has been crystallized in a crystal form unique for hemoglobins. The space group is trigonal, P3121, or the enantiomorph P3221, a = b = 55.85 A, c = 159.10 A. There are three tetrameric molecules in the unit cell with two gamma-chains per asymmetric unit.
D003460:Crystallization; D006455:Hemoglobins, Abnormal / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D046911:Macromolecular Substances; D008706:Methemoglobin / Q000302:isolation & purification; D011487:Protein Conformation; D013789:Thalassemia / Q000097:blood*; D014961:X-Ray Diffraction
D006455:Hemoglobins, Abnormal; D046911:Macromolecular Substances; D008706:Methemoglobin; C030448:hemoglobin Bart's