title: Culture of Vibrio extorquens from severe, chronic skin ulcers in a Puerto Rican woman.
abstract: A 48-year-old Puerto Rican woman developed extensive ulcers on her buttocks, right arm, and thighs over a 3 1/2-year period. The lesions began as small, subcutaneous nodules which subsequently ulcerated and expanded up to 19 cm in diameter. Biopsy of both ulcerated and nonulcerated lesions showed acid-fast bacilli. Culture of both types of lesions grew Vibrio extorquens, a partially acid-fast methanolophilic organism not previously associated with disease in humans. The patient developed agglutinating antibody, titer 1:80, to this organism. The disease responded to treatment with antibiotics to which the organism was sensitive in vitro.
mesh_terms: D005260:Female; D006801:Humans; D007612:Kanamycin / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012874:Skin Diseases, Infectious / Q000175:diagnosis* / Q000188:drug therapy; D012883:Skin Ulcer / Q000382:microbiology*; D014733:Vibrio / Q000187:drug effects / Q000302:isolation & purification*; D014735:Vibrio Infections / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D007612:Kanamycin