title: [Comparative study of the antiglaucomatous activity of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsin-induced experimental glaucoma].
abstract: The antiglaucomatous effects of Glauplex 2 and pilocarpine nitrate on alpha-chymotrypsine-induced experimental glaucoma were studied in 8 rabbits. Changes in intraocular pressure were measured over a period of 12 hours after a single instillation of Glauplex 2 or two instillations of 2.6 p. cent pilocarpine nitrate at t = 0 and t = 6 hours. The antihypertensive effect of a single instillation of Glauplex 2 was shown to be approximately equivalent to that of two instillations of 2.6 p. cent pilocarpine nitrate.
mesh_terms: D000818:Animals; D002918:Chymotrypsin; D003692:Delayed-Action Preparations; D004195:Disease Models, Animal; D005901:Glaucoma / Q000139:chemically induced / Q000188:drug therapy*; D009883:Ophthalmic Solutions; D010862:Pilocarpine / Q000627:therapeutic use*; D011817:Rabbits; D014065:Tonometry, Ocular
chemical_list: D003692:Delayed-Action Preparations; D009883:Ophthalmic Solutions; D010862:Pilocarpine; C018639:Piloplex; D002918:Chymotrypsin
vernacular_title: Etude comparative de l'activité antiglaucomateuse de Glauplex 2 et du nitrate de pilocarpine sur le glaucome expérimental à l'alpha-chymotrypsine.