Charcoal hemoperfusion for treatment of ethchlorvynol overdose.
Charcoal hemoperfusion is commonly employed to treat overdose of a number of drugs. There are varying reports of its efficacy in the treatment of ethchlorvynol overdose. Herein is reported a case of ethchlorvynol overdose successfully treated with charcoal hemoperfusion within 5 h of ingestion of 12.5 g of the drug. The patient was deeply comatose at that time but recovered consciousness at the end of 4 h of hemoperfusion. Ethchlorvynol clearance over the charcoal varied from 118 to 147 ml/min. There were no bleeding complications. Prompt charcoal hemoperfusion may be an effective mode of treatment in cases of ethchlorvynol intoxication.
D000328:Adult; D002606:Charcoal / Q000008:administration & dosage* / Q000627:therapeutic use; D003128:Coma / Q000139:chemically induced; D004984:Ethchlorvynol / Q000097:blood / Q000506:poisoning*; D005260:Female; D006464:Hemoperfusion; D006801:Humans
D002606:Charcoal; D004984:Ethchlorvynol