Diazepam-induced NaCl solution intake: independence from renal factors.
Rehydrating rats injected with diazepam (8 mg/kg, SC) increased their intake of 2.0% NaCl solution. Neither bilateral nephrectomy nor bilateral ureter ligation interfered with the increased NaCl solution ingestion produced by diazepam. It is concluded that the increased intake of the NaCl solution is not secondary to renal water-electrolyte losses nor dependent upon intact renal benzodiazepine receptors.
D000818:Animals; D003975:Diazepam / Q000494:pharmacology*; D004327:Drinking Behavior / Q000187:drug effects*; D007668:Kidney / Q000502:physiology*; D008297:Male; D009392:Nephrectomy; D051381:Rats; D012965:Sodium Chloride; D014513:Ureter / Q000502:physiology
D012965:Sodium Chloride; D003975:Diazepam