Nephrotoxicity of phenazopyridine.
A young man developed reversible acute renal failure after a large overdose of phenazopyridine. The renal failure was treated by peritoneal dialysis. Analysis of blood and urine samples failed to demonstrate the parent drug but a metabolite with similar ultraviolet absorption was detected. No parent drug or metabolites were detected in the peritoneal dialysate.
D000328:Adult; D000631:Aminopyridines / Q000506:poisoning*; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008297:Male; D010621:Phenazopyridine / Q000378:metabolism / Q000506:poisoning*
D000631:Aminopyridines; D010621:Phenazopyridine