[Role of histiocytic and parenchymatous elements of the liver in biosynthesis of reactive blood glycoproteins (haptoglobin and ceruloplasmin)].
Synthesis of haptoglobin and ceruloplasmin was found to occur in liver parenchyma under conditions of obligatory participation of the tissue mesenchymal structural elements. Dependence of the blood glycoproteins hyperproduction on the processes of proliferation, occurring in hystiocytic structural elements of liver, was detected after administration into rabbits of zymosan, which stimulated the reticuloendothelial cells, of turpentine (causing inflammation in subcutaneous fatty tissue) or of intracellular cytoplasmic soluble antigens of beta-haemolytic streptococcus A.
D000818:Animals; D002455:Cell Division; D002570:Ceruloplasmin / Q000096:biosynthesis*; D006242:Haptoglobins / Q000096:biosynthesis*; D006644:Histiocytes / Q000166:cytology / Q000378:metabolism*; D006651:Histocytochemistry; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D011817:Rabbits; D015054:Zymosan / Q000494:pharmacology
D006242:Haptoglobins; D015054:Zymosan; D002570:Ceruloplasmin
Rol' gistiotsitarnykh i parenkhimatoznykh élementov pecheni v biocinteze reaktivnykh glikoproteinov krovi (gaptoglobina i tseruloplazmina).