title: [Incidence of antithyroglobulin and antimicrosomal antibodies in thyroid pathology].
abstract: A systematic study of antibodies directed against thyroglobulin on one side, and against microsomes on the other side, was made during two consecutive years on a hospital population of out patients supposed to suffer from a thyroid affection: about one fourth of the serums is positive for at least one of the two antibodies; the benefit of searching antimicrosomal antibodies is capital, but the simultaneous research of thyroglobulin antibodies is necessary. The consequences of this screening are developed in three main pathologic fields: hypothyroidism (real frequency of Hashimoto's disease in spontaneous myxodema); hyperthyroidism (prognostic implications of antibodies presence); normothyroid subjects (screening of clinical thyroid abnormalities).
mesh_terms: D001323:Autoantibodies / Q000032:analysis*; D006042:Goiter / Q000276:immunology; D006111:Graves Disease / Q000276:immunology; D006386:Hemagglutination Tests; D006801:Humans; D006980:Hyperthyroidism / Q000276:immunology; D007037:Hypothyroidism / Q000276:immunology; D008861:Microsomes / Q000276:immunology*; D013954:Thyroglobulin / Q000276:immunology*; D013959:Thyroid Diseases / Q000276:immunology*; D013967:Thyroiditis, Autoimmune / Q000276:immunology
chemical_list: D001323:Autoantibodies; D013954:Thyroglobulin
vernacular_title: Etude de la fréquence des anticorps antithyroglobuline et antimicrosomaux en pathologie thyroïdienne.