[Effect of various cytostatics and radiotherapy on serum iron and copper levels in lymphoma patients].
Forty four patients with lymphoma, active stage, were examined. Polychemotherapy (PChTh), one course in various combinations of drugs were applied to 32 of them and to 18--radical beam therapy (above and under diaphragmal). Low iron and high copper in serum was found in all patients prior to treatment. Elevated serum iron (SI) was found in the patients after the course of PChTh, whereas the values of copper were almost unaffected. In the patients, after radical beam therapy, SI and serum copper tended to normalization, in parallel with the abating of the morbid process. The effect of cytostatics upon the SI level is discussed as well as the necessity of parallel determination of some other indices, serum copper in particular, in the assessment of the activity of the morbid process.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003300:Copper / Q000097:blood*; D004359:Drug Therapy, Combination; D006689:Hodgkin Disease / Q000097:blood / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D007501:Iron / Q000097:blood*; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000532:radiotherapy / Q000628:therapy*
D000970:Antineoplastic Agents; D003300:Copper; D007501:Iron
Vliianie na niakoi tsitostatitsi i luchelechenieto vurkhu nivoto na zheliazoto i medta v seruma u bolni s limfomi.