Enhancement of Moraxella bovis-induced keratitis of mice by exposure of the eye to ultraviolet radiation and ragweed extract.
Effects of a ragweed extract and ultraviolet (UV) radiation on Moraxella bovis-induced keratitis of DBA/2J mice were investigated. Mouse eyes were exposed to ragweed extract and/or UV radiation during induction of keratitis. Pathogenesis was enhanced by exposure to ragweed extract alone and by exposure to UV radiation alone. It was enhanced most when eyes were exposed to ragweed extract and UV radiation.
D000485:Allergens / Q000633:toxicity*; D000818:Animals; D001424:Bacterial Infections / Q000473:pathology / Q000662:veterinary*; D003315:Cornea / Q000473:pathology; D005260:Female; D007634:Keratitis / Q000473:pathology / Q000662:veterinary*; D051379:Mice; D008815:Mice, Inbred Strains; D010936:Plant Extracts; D012376:Rodent Diseases / Q000473:pathology*; D014466:Ultraviolet Rays / Q000009:adverse effects*
D000485:Allergens; D010936:Plant Extracts