A prospective study of the risk of developing multiple sclerosis in optic neuritis in a tropical and sub-tropical area.
110 cases of optic neuritis were prospectively studied. 62 (56%) developed multiple sclerosis, 13 were lost to survey. However, eight of these had recurrent episodes of optic neuritis. If recurrent episodes of optic neuritis are accorded the same significance as demyelination elsewhere in the CNS, then the incidence of multiple sclerosis in the series rose to 71%, similar to that predicted on an actuarial basis.
D000293:Adolescent; D000328:Adult; D001315:Australia; D002648:Child; D004292:Dominance, Cerebral; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis*; D009902:Optic Neuritis / Q000175:diagnosis*; D011446:Prospective Studies; D012306:Risk; D014329:Tropical Climate