9-(5-Carboxypentylamino)-acridine. An affinity adsorbent ligand for Electrophorus acetylcholinesterase.
We have developed a simple method for the synthesis of the ligand 9-(5-carboxypentylamino)-acridine and the resulting affinity adsorbent using Sepharose CL-4B. This affinity adsorbent is efficient and specific for purification acetylcholinesterase (acetylcholine acetylhydrolase, EC 3.1.1.7) from Electrophorus electricus electric organ.
D000110:Acetylcholinesterase / Q000302:isolation & purification*; D000345:Affinity Labels / Q000138:chemical synthesis; D000609:Aminoacridines / Q000138:chemical synthesis*; D000818:Animals; D002846:Chromatography, Affinity / Q000379:methods; D004593:Electrophorus / Q000378:metabolism*
D000345:Affinity Labels; D000609:Aminoacridines; C026950:9-(5-carboxypentylamino)acridine; D000110:Acetylcholinesterase