Carcinoembryonic antigen levels in cervico-vaginal fluid from patients with intra-epithelial and invasive carcinoma of the cervix.
Carcinoembryonic antigen (CEA) levels have been measured in cervico-vaginal washout fluid using the direct CEA Roche radioimmunoassay. Raised CEA levels were found associated with cervical intra-epithelial neoplasia and invasive carcinoma (85% above 300 ng/ml) compared with benign cervical lesions (29% above 300 ng/ml), suggesting that estimation of local CEA levels might be a useful adjunct to cytology and biopsy in the investigation of cervical neoplasia.
D001826:Body Fluids / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002278:Carcinoma in Situ / Q000276:immunology; D005260:Female; D006801:Humans; D011863:Radioimmunoassay; D002577:Uterine Cervical Diseases / Q000276:immunology; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
D002272:Carcinoembryonic Antigen