Synthesis and preliminary biological investigations of O-sulphated dermorphin.
Synthesis by a classical solution method of a sulphated analogue of dermorphin is reported. The product has proved to be devoid of any peripheral and central opiate- or CCK-like activity in the tests assayed.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D006168:Guinea Pigs; D066298:In Vitro Techniques; D051379:Mice; D009842:Oligopeptides / Q000138:chemical synthesis*; D051381:Rats
D009842:Oligopeptides; C038603:dermorphin, O-sulfated