Tuftsin analogs with D-amino acid residues.
The syntheses of nine tuftsin analogs containing D-amino acid residues are described. Their biological activity is discussed in terms of possible influence of the configurational change in definite position of the peptide chain on the preservation of beta-bend conformation of the tetrapeptide.
D000596:Amino Acids; D007128:Immunoglobulin Fragments; D007202:Indicators and Reagents; D008722:Methods; D009904:Optical Rotation; D011487:Protein Conformation; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014405:Tuftsin / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D000596:Amino Acids; D007128:Immunoglobulin Fragments; D007202:Indicators and Reagents; D014405:Tuftsin