[Results of functional scintigraphy using 131J-hippurate in preoperative diagnosis of patients with kidney tumors: influence on surgical treatment and predictive value for retentional serum levels].
156 patients with renal tumors were studied using 131J-hippurate to assess the validity of functional scintigraphy in preoperative diagnosis and to compare it with the serum levels of Creatinine and Urea before and after tumor nephrectomy. If the contralateral, non tumor bearing kidney had a clearance (RNCL) of more than 200 ml/min, no pathological elevation was found postoperatively. If the RNCL was between 150 and 200 ml/min, the postoperatively elevated serum levels of Creatinine and Urea normalized within 3 weeks after surgery. Elevation persisted for longer than 3 weeks if the RNCL was between 100 and 150 ml/min. In RNCL below 120 ml/min an elevation was found even 6 months after surgery. Only if the RNCL was less than 100 ml/min (2% of all cases), instead of tumornephrectomy, an organ-conserving surgery was performed. In these cases, the results of renal scintigraphy yielded additional information in deciding the type of non-radical surgery. Therefore, renal functional scintigraphy does not need to be performed in patients with renal tumors under the following conditions: 1. no elevation of Creatinine and Urea preoperatively and 2. normal morphological findings (sonography, IVP, angiography, CT) of the contralateral kidney.
D003404:Creatinine / Q000097:blood; D005260:Female; D006626:Hippurates; D006801:Humans; D007457:Iodine Radioisotopes; D007680:Kidney Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D008657:Metabolic Clearance Rate; D009392:Nephrectomy; D011300:Preoperative Care; D011877:Radionuclide Imaging; D014508:Urea / Q000097:blood
D006626:Hippurates; D007457:Iodine Radioisotopes; D014508:Urea; D003404:Creatinine
Ergebnisse der Funktionsszintigraphie mit 131J-Hippuran in der präoperativen Diagnostik von Nierentumorpatienten: Einfluss auf operatives Vorgehen und Vorhersagewert für das Retentionsverhalten.