[Infantile myoclonic encephalopathy with opsoclonus and neuroblastoma. Apropos of 2 cases].
Two cases of infantile myoclonic encephalopathy with opsoclonus and neuroblastoma are reported. One of them was observed in a 16-month-old boy and the remaining one in a 13-month-old girl. In both cases the tumour was a stade III abdominal neuroblastoma. Urinary catecolamine excretion was increased in the girl and that of VMA in both patients. Treatment of the tumour with surgery, radiotherapy and chemotherapy resulted in a immediate disappearance of the neurologic picture in the girl. The same measures were equally successful in the boy implemented with a course of ACTH. Both children are free of tumour three years later, and they do not bear any psychomotor sequelae. The main features of this rare association are briefly commented.
D000008:Abdominal Neoplasms / Q000150:complications* / Q000628:therapy / Q000652:urine; D002395:Catecholamines / Q000652:urine; D005133:Eye Movements; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009207:Myoclonus / Q000150:complications*; D009447:Neuroblastoma / Q000150:complications* / Q000628:therapy / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
D002395:Catecholamines; D014642:Vanilmandelic Acid
Encefalopatía mioclónica infantil con opsoclonus y neuroblastoma. A propósito de dos observaciones.