A case report of myasthenia gravis associated with Hashimoto's thyroiditis.
An unusual case of myasthenia gravis is presented. The disease was clinically established in a 71-year-old Japanese woman by an electromyographic, pharmacologic test and anti-acetylcholine receptor (anti-AChR) antibodies demonstrated in the circulating blood. The coexistence of Hashimoto's thyroiditis was diagnosed by the presence of a diffuse thyroid enlargement, anti-thyroglobulin and anti-microsomal antibodies and a lowered thyroidal 131I uptake. A delusion of persecution developed during the treatment with pyridostigmine and ephedrine chloride, but the symptom disappeared after discontinuing the use of ephedrine chloride.
D000368:Aged; D000906:Antibodies / Q000032:analysis*; D004809:Ephedrine / Q000009:adverse effects; D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D008861:Microsomes / Q000276:immunology; D009157:Myasthenia Gravis / Q000150:complications*; D011605:Psychoses, Substance-Induced; D011950:Receptors, Cholinergic / Q000276:immunology; D013954:Thyroglobulin / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications*
D000906:Antibodies; D006680:HLA Antigens; D011950:Receptors, Cholinergic; D013954:Thyroglobulin; D004809:Ephedrine