Inhibition of food stimulated acid secretion by fenoctimine, a new anti-secretory agent.
The effect of fenoctimine, a new anti-secretory agent, has been studied on food stimulated acid secretion in six normal volunteers. When tested between 2 and 4 h after dosing, and compared with placebo, fenoctimine 50 mg inhibited acid secretion by a mean of 29%, 150 mg by 43% and 250 mg by 47%.
D000328:Adult; D001639:Bicarbonates / Q000378:metabolism; D005502:Food; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D010880:Piperidines / Q000494:pharmacology*
D001639:Bicarbonates; D010880:Piperidines; C037813:fenoctimine