[Diffusion capacity of the hematoparenchymal barrier for oxygen in the breathing of helium-oxygen gas mixtures].
In 25 rabbits with local anesthesia, recordings of partial oxygen pressure in the hindlimb arterial and venous blood, oxygen tension in muscles and some other parameters followed by calculation of the muscle hematoparenchymatous barrier, revealed that, in inhalation of normoxic helio--oxygen mixture, the hematoparenchymatous barrier's diffusion capacity for oxygen increases as compared with the analogous value in breathing with air. In inhalation of hypoxic helio--oxygen and nitrogen--oxygen mixtures (11% O2), the barrier's diffusion capacity for oxygen proves higher than in breathing with respective normoxic gas mixtures. A possible pharmacological effect of helium influence upon plasmatic membranes of the hematoparenchymatous barrier's components is discussed.
D000818:Animals; D001274:Atmospheric Pressure; D055598:Chemical Phenomena; D002621:Chemistry; D006371:Helium / Q000378:metabolism*; D000860:Hypoxia / Q000378:metabolism; D008297:Male; D010100:Oxygen / Q000502:physiology*; D010101:Oxygen Consumption; D010313:Partial Pressure; D011653:Pulmonary Diffusing Capacity; D011817:Rabbits; D012119:Respiration
D006371:Helium; D010100:Oxygen
Diffuzionnaia sposobnost' gematoparenkhimatoznogo bar'era dlia kisloroda v usloviiakh dykhaniia gelio-kislorodnymi gazovymi smesiami.