Sulfonamide inhibition of rat hepatic uroporphyrinogen I synthetase activity and the biosynthesis of heme.
D000624:5-Aminolevulinate Synthetase / Q000378:metabolism; D000642:Ammonia-Lyases / Q000037:antagonists & inhibitors*; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006418:Heme / Q000096:biosynthesis*; D006419:Heme Oxygenase (Decyclizing) / Q000378:metabolism; D011163:Hydroxymethylbilane Synthase / Q000037:antagonists & inhibitors*; D008099:Liver / Q000201:enzymology*; D008862:Microsomes, Liver / Q000201:enzymology; D051381:Rats; D013416:Sulfamerazine / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology*
D013449:Sulfonamides; D006418:Heme; D003577:Cytochrome P-450 Enzyme System; D006419:Heme Oxygenase (Decyclizing); D000624:5-Aminolevulinate Synthetase; D011163:Hydroxymethylbilane Synthase; D000642:Ammonia-Lyases; D013416:Sulfamerazine