title: Gastric ulceration after Nissen fundoplication.
abstract: Thirteen patients developed gastric ulcers between 6 months and 8.5 years after Nissen fundoplication. Eight patients presented with epigastric pain alone, 3 with bleeding alone and 2 with both pain and bleeding. Nine ulcers (69 per cent) were high on the lesser curve, close to the fundoplication and 7 of these patients had recurrent hernias. Anatomical distortion produced by fundoplication is probably the most important aetiological factor, though gastric distention, bile reflux gastritis and ischaemia may be contributory.
mesh_terms: D000328:Adult; D000368:Aged; D004947:Esophagus / Q000601:surgery*; D005260:Female; D005748:Gastric Fundus / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D013276:Stomach Ulcer / Q000209:etiology*; D013997:Time Factors