Radiation retinopathy following treatment of posterior nasal space carcinoma.
Posterior nasal space carcinoma has a high mortality and most patients are treated with radiotherapy. Radiation retinopathy was encountered in 7 out of 10 survivors included in this study. Five of the affected patients lost vision as a result of the retinopathy. One patient required laser photocoagulation and responded well to this treatment. There was a variation in the severity of the retinopathy among the patients studied despite the fact that all patients received a similar dose of radiotherapy. We suspect that previously unrecognised factors in the planning of radiotherapy fields may explain this difference.
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects*; D012160:Retina / Q000473:pathology / Q000528:radiation effects; D012164:Retinal Diseases / Q000209:etiology* / Q000473:pathology; D014786:Vision Disorders / Q000209:etiology