Possible induction by blood transfusion of immunological tolerance against growth of transplanted tumors in mice.
That blood transfusions aid kidney graft survival is well known. Our data show that blood transfusions, except for the red blood cell component, promote growth of transplanted tumors in mice. These clinical and experimental observations suggest that blood transfusions may induce some immunological tolerance.
D000818:Animals; D001803:Blood Transfusion; D007108:Immune Tolerance; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology*