title: Changes in total body calcium balance with exercise in the rat.
abstract: The purpose of this study was to evaluate the effect of deconditioning on the total body calcium in rats. Two separate experiments were performed using female Sprague-Dawley rats, 187-266 days of age. Total body calcium was measured in experimental and control rats during and following several weeks of voluntary exercise. The slope from the least-squares fit of total body calcium with time was used to obtain an average calcium balance for each animal during each study period. In both groups the exercised rats had a significantly decreased calcium balance after cessation of exercise, whereas no significant change was seen in nonexercised controls. In both groups, the exercised animals gained calcium at a significantly greater rate than controls. Our findings indicate that while exercised rats may gain calcium at a faster rate compared with nonexercising controls, the rate of gain following cessation of exercise is less than the controls.
mesh_terms: D000367:Age Factors; D000818:Animals; D001835:Body Weight; D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D005260:Female; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014893:Weightlessness
chemical_list: D002118:Calcium