Inhibitory effects of autologous hepatic tumor suspension on the development of liver cell carcinoma in rats.
Inoculation with a crude suspension prepared from autologous liver cell carcinoma inhibited the development of liver tumor in cirrhotic rats exposed to 3'-methyl-4-diethylaminoazobenzene (3'-Me-DAB). The suspension had also an inhibitory effect on the growth of tumor in rats bearing liver cell carcinoma. The results obtained suggest that a close relationship exists between tumor-associated antigens and onco-development.
D000818:Animals; D000951:Antigens, Neoplasm; D008103:Liver Cirrhosis / Q000276:immunology; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology* / Q000473:pathology; D008297:Male; D008749:Methyldimethylaminoazobenzene; D009368:Neoplasm Transplantation; D011230:Precancerous Conditions / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D014182:Transplantation, Autologous
D000951:Antigens, Neoplasm; D008749:Methyldimethylaminoazobenzene