Intraventricular and intravenous use of amphotericin B in a case of non-surgical cerebral aspergillosis.
After a short review of the literature regarding aspergillosis, the authors report a case of a 7-year-old child suffering from cerebral aspergillosis with disseminated lesions. The authors emphasize the use of amphotericin B both intraventricularly and intravenously to obtain a longer survival when surgery is impossible because of the presence of multiple abscessual lesions in central nervous system. Authors' experience shows that the intraventricular administration of amphotericin B is well tolerated and does not cause collateral effects of the parenteral way.
D000666:Amphotericin B / Q000627:therapeutic use*; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002648:Child; D006801:Humans; D007276:Injections, Intraventricular; D008297:Male; D014057:Tomography, X-Ray Computed
D000666:Amphotericin B