title: The intramucosal cysts of the stomach in Japanese subjects having focal (elevated) dysplasia.
abstract: The frequency of intramucosal cysts underneath focal (elevated) neoplastic lesions (which include epithelial dysplasia and early gastric cancer) was recorded in eighty-eight resected stomachs. The mean cyst index (i.e. the amount of intramucosal cysts divided by the amount--in cm--of gastric mucosa analyzed) underneath such lesions was 30.9 (SD +/- 16.9), while in adjacent normal-looking gastric mucosa it was 9.4 (SD +/- 8). The difference was significant (P less than 0.001). The cyst index was highest in female patients, underneath focal (elevated) dysplasias. Previous work indicated that the normal-looking gastric mucosa in Japanese patients with peptic ulcer disease was 3.4 (SD +/- 6.6). The present findings appear to suggest that cystic formation in gastric mucosa may herald an early neoplastic growth at the luminal aspect in some of the cysts.
mesh_terms: D000367:Age Factors; D003560:Cysts / Q000473:pathology*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013272:Stomach Diseases / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology