[Therapeutic application of vitamin D, its derivatives and analogues (author's transl)].
The synthesis of vitamin D derivatives and analogues, more especially that of 25-hydroxyvitamin D, 1, 25-dihydroxyvitamin D et l alpha-hydroxyvitamin D has opened a new field of investigation in pediatric pharmacology. These substances allows to achieve replacement therapy in pathological states characterized by a decreased formation of 25-hydroxyvitamin D (hepato-cellular diseases) or, 1, 25-dihydroxyvitamin D (renal diseases). Moreover, their utilisation at pharmacological doses has improved the therapeutic results in a number of pediatric diseases. In the present report are more especially summarized the results obtained with these three derivatives in patients with secondary hyperparathyroidism, hypo or pseudo-hypoparathyroidism.
D002112:Calcifediol; D002117:Calcitriol / Q000627:therapeutic use; D002648:Child; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use; D006961:Hyperparathyroidism / Q000188:drug therapy*; D007011:Hypoparathyroidism / Q000188:drug therapy*; D010281:Parathyroid Hormone / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000188:drug therapy*; D014807:Vitamin D / Q000627:therapeutic use*
D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D014807:Vitamin D; D002117:Calcitriol; D002112:Calcifediol
Utilisation thérapeutique de la vitamine D, de ses dérivés et de ses analogues.