title: [Comparative antirachitic activity of 1,25-dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 in the chick].
abstract: 1,25-dihydroxy vitamin D3 and its synthetic analogue 1 alpha-hydroxy vitamin D3 were administered into chicken at the doses of 0.025, 0.05 and 0.1 micrograms per day within 25 days. Effect of the vitamins was estimated by a net gain of biomass, by biochemical alterations in blood, synthesis of calcium-binding protein, relative mass of parathyroid glands and by content of inorganic residue in bone tissue. Both vitamin preparations exhibited similar antirickety activity.
mesh_terms: D000818:Animals; D001835:Body Weight; D001842:Bone and Bones / Q000032:analysis; D002117:Calcitriol / Q000627:therapeutic use*; D002645:Chickens; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008903:Minerals / Q000032:analysis; D010280:Parathyroid Glands / Q000473:pathology; D012279:Rickets / Q000188:drug therapy*; D064030:S100 Calcium Binding Protein G / Q000097:blood
chemical_list: D006887:Hydroxycholecalciferols; D008903:Minerals; D064030:S100 Calcium Binding Protein G; D002117:Calcitriol; C008088:alfacalcidol
vernacular_title: Sravnenie antirakhiticheskoĭ aktivnosti 1,25-dioksivitamina D3 i 1 alpha-oksivitamina D3 u tsypliat.