Uveal coloboma associated with amniotic band syndrome.
A baby girl had constriction bands and digital amputations typical of the amniotic band syndrome, as well as a typical uveal coloboma in a slightly microphthalmic eye. A small, free-floating amniotic band may have lodged in the fetal uveal cleft at 5 to 6 weeks of gestation, preventing closure of the cleft and thus resulting in this first reported instance of an association between amniotic band syndrome and an isolated uveal coloboma.
D000652:Amniotic Band Syndrome / Q000150:complications* / Q000175:diagnosis; D003103:Coloboma / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007498:Iris / Q000002:abnormalities; D008850:Microphthalmos / Q000209:etiology; D014602:Uvea / Q000002:abnormalities*