title: [Structural modifications and hematic variations in pregnant and/or suckling rats kept on a purified diet with high content of animal proteins].
abstract: The effects of a high protein diet (casein 40%, lactalbumin 20%) were evaluated in pregnant and/or suckling rats. Histological studies of the organs showed structural alterations to the liver, adrenal cortex, kidneys and heart accompanied by significant metabolic changes in blood glucose and triglyceride levels. Overall the experimental results encourage the belief excessive intake of animal protein, particularly at an early stage, may do specific damage to the normal course of pregnancies, given the low birth rate and high incidence of perinatal mortality observed in the offspring produced by mothers given high protein diets throughout pregnancy.
mesh_terms: D000302:Adrenal Cortex / Q000187:drug effects; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D004044:Dietary Proteins / Q000009:adverse effects*; D005260:Female; D006321:Heart / Q000187:drug effects; D007774:Lactation; D008055:Lipids / Q000097:blood; D008099:Liver / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats
chemical_list: D001786:Blood Glucose; D004044:Dietary Proteins; D008055:Lipids
vernacular_title: Modificazioni strutturali e variazioni ematiche in ratte riceventi in gestazione e/o allattamento dieta purificata con elevato apporto di proteine animali.