Available immunoglobulin A antibodies in mouth rinses and implantation of Streptococcus mutans.
Immunoglobulin A (IgA) antibodies reacting with Streptococcus mutans were analyzed in mouth rinses from 38 adults. Antibody activity was determined by an enzyme-linked immunosorbent assay. The IgA antibody activity varied considerably in samples from different individuals. Of the 38 subjects, 12 volunteered in an implantation experiment and were challenged with streptomycin-resistant S. mutans. The results indicated that individuals with relatively high IgA antibody activity in mouth rinses more rapidly eliminated the challenge strain than subjects with low IgA antibody activity.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000276:immunology*; D012463:Saliva / Q000276:immunology; D013295:Streptococcus mutans / Q000276:immunology*
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A