Immune response to extracted pollen residues.
Extracted pollen residues with three to five orders of magnitude less reextractable allergenic activity were found to be equal or better in the capacity of priming for an antibody formation in guinea pigs against the native pollen extract in comparison with the priming capacity of the native extracted material itself. Because the modification of the extract does not interfere with the run of an immune response in animals primed against the native structures of the allergen in question, the priming capacity needs attention and further optimization. Therefore this study investigated the measurement of the priming capacity of allergenic preparations.
D000485:Allergens / Q000276:immunology; D000818:Animals; D000906:Antibodies / Q000032:analysis; D006168:Guinea Pigs; D008297:Male; D010323:Passive Cutaneous Anaphylaxis / Q000187:drug effects; D010936:Plant Extracts / Q000276:immunology*; D011058:Pollen / Q000276:immunology*; D013997:Time Factors
D000485:Allergens; D000906:Antibodies; D010936:Plant Extracts