title: Experimental models of splenic dysfunction.
abstract: Animal simulations of splenic disorders are described including alterations in portal and splenic vein flow, induction of splenic sequestration, models of hyposplenism and murine hereditary spherocytosis.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D008026:Ligation; D051379:Mice; D011817:Rabbits; D013154:Spleen / Q000503:physiopathology / Q000637:transplantation; D013158:Splenic Diseases / Q000503:physiopathology; D013162:Splenic Vein / Q000473:pathology