[Gonadotropin release following hypothalamic electrical stimulation of the Macaca fuscata].
The effect of electrical stimulation on hypothalamic nuclei was studied by using a stereotaxic operation and in vitro bioassay of luteinizing hormone (LH) in the macaca fuscata. The results were as follows: The serum LH level was increased when the arcuate nucleus or the ventromedial nucleus was stimulated at 250 mu A and 500 mu A. The serum LH level was not increased when the paraventricular nucleus or supraoptic nucleus was stimulated at 250 mu A and 500 mu A. When the medial preoptic nucleus was stimulated at 250 mu A, the serum LH level was not increased. However, the stimulation of 500 mu A increased the serum LH level. The stimulation of the lateral preoptic nucleus did not increase the serum LH at 250 mu A and 500 mu A. The half lives of LH were 35.4 min., 33.4 min., 48.4 min., 43.1 min. These results were different from the half life of human LH. The contribution of various hypothalamic nuclei to the release of LH was discussed.
D000818:Animals; D004558:Electric Stimulation; D005260:Female; D007031:Hypothalamus / Q000502:physiology*; D007986:Luteinizing Hormone / Q000378:metabolism*; D008251:Macaca / Q000502:physiology*
D007986:Luteinizing Hormone