Dissolution of gallstones following thyroxine administration. A case report.
A case of disappearance of five radiolucent gallstones within six months is reported. During this time the patient was taking carbimazole and thyroxine orally for toxic goiter. Three more cases of disappearance of gallstones after iatrogenic alteration in the thyroid status by thyroid hormone administration have been published. It is concluded that thyroid hormone may play a role in the dissolution of gallstones by altering the metabolism of cholesterol.
D000284:Administration, Oral; D000328:Adult; D002231:Carbimazole / Q000008:administration & dosage; D002769:Cholelithiasis / Q000188:drug therapy*; D005260:Female; D006111:Graves Disease / Q000188:drug therapy; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D012075:Remission, Spontaneous; D012995:Solubility; D013974:Thyroxine / Q000008:administration & dosage*; D013997:Time Factors
D006728:Hormones; D002231:Carbimazole; D013974:Thyroxine