title: Use of antibiotics in open tibial fractures.
abstract: Data concerning 1102 open fractures are presented with bacteriologic and antibiotic considerations analyzed in 363 open tibiae fractures treated in three prospective one-year studies during the period from 1970 to 1980. The highest infection rate was in open tibiae receiving no antibiotics (24%, 6 infections in 25 open tibial fracture wounds), and the lowest was in the group receiving a cephalosporin and an aminoglycoside (4.5%, 5 infections in 109 open tibial fracture wounds).
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005597:Fractures, Open / Q000150:complications*; D006801:Humans; D011292:Premedication; D011446:Prospective Studies; D013978:Tibial Fractures / Q000150:complications*; D014946:Wound Infection / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents