Effects of external renal hypothermia on postischemic hemodynamics.
In the rabbit model renal cortical blood flow after 60 min of normothermic ischemia is seen to rise significantly in the early reperfusion period. Under otherwise identical conditions this phenomenon is absent after hypothermic ischemia produced by surface cooling of the kidney and in sham-operated kidneys. It is still unclear whether postischemic hyperemia is a physiologic counterregulatory mechanism in response to 60-min normothermic ischemia of the rabbit kidney or a contributory factor in the development of acute postischemic renal failure.
D058186:Acute Kidney Injury / Q000209:etiology; D000818:Animals; D005260:Female; D006439:Hemodynamics; D006940:Hyperemia / Q000150:complications; D007036:Hypothermia, Induced; D007511:Ischemia / Q000150:complications / Q000503:physiopathology*; D007672:Kidney Cortex / Q000098:blood supply*; D008297:Male; D011817:Rabbits; D012079:Renal Circulation