Management of severe reflux in the patient with cyclophosphamide cystitis.
Cyclophosphamide cystitis with a high grade of vesicoureteral reflux can lead to rapid renal deterioration. Conventional ureteral reimplantation is inadvisable and urinary diversion, although providing a temporary solution, could lead to long-term complications, particularly in children. We present a case of cyclophosphamide cystitis with vesicoureteral reflux and upper tract deterioration managed successfully with ileocecocystoplasty. This method of management should be considered early in such a patient.
D002432:Cecum / Q000601:surgery; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000009:adverse effects*; D003556:Cystitis / Q000139:chemically induced*; D005260:Female; D006417:Hematuria / Q000139:chemically induced; D006801:Humans; D007082:Ileum / Q000601:surgery; D001743:Urinary Bladder / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000139:chemically induced / Q000601:surgery*
D003520:Cyclophosphamide