Relapsing eosinophilic myositis.
We report 3 male patients with a unique eosinophilic myositis of unknown etiology who appear to have a benign course. The most striking feature in 2 patients was relapsing myalgias with lower extremity predilection and tendency for spontaneous recovery. Laboratory studies showed peripheral eosinophilia, elevated CPK, and EMG consistent with a myositic pattern. Muscle biopsies showed myositis characterized by focal necrosis and degeneration with an inflammatory infiltrate predominantly composed of histiocytes and eosinophils. Skin and fascia were normal.
D000328:Adult; D001706:Biopsy; D003402:Creatine Kinase / Q000378:metabolism; D004576:Electromyography; D004802:Eosinophilia / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000175:diagnosis / Q000209:etiology*; D012008:Recurrence
D003402:Creatine Kinase