title: Percutaneous splenic artery occlusion for portal hypertension. A new mechanical technique for hypersplenism.
abstract: We studied 16 patients with hypersplenism, splenomegaly, and moderate nonbleeding portal hypertension with the purpose of discovering a hyperdynamic component associated with splenomegaly. We treated the patients' splenic hyperdynamic component and hypersplenism with a splenectomy. We measured wedge hepatic vein pressure (WHVP) before and after superior mesenteric artery occlusion by a balloon catheter, and after splenic artery (SA) occlusion by a balloon catheter. In 11 patients, following SA temporary occlusion an average WHVP reduction of 10.4 cm saline was obtained, and SA occlusion by Gianturco's coils was performed to obtain a gradual and segmentary occlusion. No colliquative phenomena were observed, and a stable decrease of WHVP with a marked improvement of peripheral cytopenia was obtained.
mesh_terms: D000328:Adult; D002404:Catheterization; D004621:Embolization, Therapeutic; D005260:Female; D006503:Hepatic Veins; D006801:Humans; D006971:Hypersplenism / Q000150:complications / Q000601:surgery / Q000628:therapy*; D006975:Hypertension, Portal / Q000209:etiology / Q000628:therapy*; D008297:Male; D008638:Mesenteric Arteries; D008722:Methods; D011312:Pressure; D013156:Splenectomy; D013157:Splenic Artery; D013163:Splenomegaly / Q000150:complications / Q000503:physiopathology / Q000628:therapy