Sperm function in patients with unexplained infertility.
Sperm function was studied in 27 patients with hitherto unexplained infertility. The ability of spermatozoa to reach the site of fertilization was assessed by laparoscopic sperm recovery from the peritoneal fluid and fimbrial rinsings and sperm fertilizing capacity with the zona-free hamster egg penetration in vitro test. The ability of spermatozoa to reach the site of fertilization correlated significantly with their fertilizing capacity in vitro, but was totally unrelated to any of the conventional criteria of semen quality, including the postcapacitation movement characteristics of the spermatozoa. Among patients with unexplained infertility, there are individuals with defects of sperm function which cannot be identified by conventional clinical techniques.
D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D013081:Sperm Motility; D013083:Sperm Transport; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000503:physiopathology*