Comparative ocular pressure elevation by medrysone, fluorometholone, and dexamethasone phosphate.
In age-, race-, and sex-matched groups, the relative abilities of medrysone, fluorometholone, and dexamethasone phosphate to elevate intraocular pressure were compared in a masked manner. Compliance was controlled by drops being given by nursing personnel. The 18 male hospitalized volunteers received commercial preparations of one of the corticosteroids to each eye four times a day for six weeks. The relative ability of medrysone, fluorometholone, and dexamethasone phosphate to raise IOP was 1, 4, and 7.6, respectively.
D000287:Administration, Topical; D000328:Adult; D000704:Analysis of Variance; D003907:Dexamethasone / Q000494:pharmacology*; D005469:Fluorometholone / Q000494:pharmacology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011282:Pregnenediones / Q000494:pharmacology*
D011282:Pregnenediones; D003907:Dexamethasone; C100283:medrysone; D005469:Fluorometholone