On estimating the difference between two probabilities, with special reference to clinical trials.
The problem of estimating the difference between the probabilities of 'success' for two binomial experiments is considered. Confidence intervals based on large-sample theory are constructed and some of their properties are compared with those of a simple technique based on exact distributions. It is shown that the former method is superior to the latter, both theoretically and practically.
D001699:Biometry; D001932:Brain Neoplasms / Q000532:radiotherapy; D002986:Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D011336:Probability; D012107:Research Design