title: Histopathologic changes in fallopian tubes subsequent to sterilization procedures.
abstract: Longitudinal serial and serial step sections of fallopian tubes from more than 100 patients, subsequent to tubal sterilization procedures, were examined. Thirteen of these patients had pregnancies following their sterilizations. The histologic findings at the previous surgical sites were compatible with what would be expected for a normal healing process. Evidence for a unique tubal epithelial process, as suggested by the terms "endosalpingiosis" or "recanalization," was lacking. Likewise, the author found no evidence of tuboperitoneal fistula formation and/or the subsequent occurrence of pregnancy secondary to localized endometriosis. The histologic notations of proximal luminal dilatation, plical attenuation, chronic inflammatory infiltrates with pseudopolyp formation, and the findings of plical thickening in the distal segment of remaining tube after an interruption type of procedure seem to be associated with the length of time from the sterilization procedure. These may be factors related to the apparent reduced success rate, with time, of microsurgical reanastomotic procedures.
mesh_terms: D000328:Adult; D004108:Dilatation, Pathologic; D005187:Fallopian Tubes / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008855:Microscopy, Electron, Scanning; D011247:Pregnancy; D013246:Sterilization, Tubal; D013997:Time Factors; D014945:Wound Healing