title: Plasma vasopressin concentration in the anaesthetized dog before, during and after atrial distension.
abstract: Plasma vasopressin (AVP) concentration in dogs anaesthetized with chloralose was measured by radioimmunoassay and was within the range of 2-5 pg/ml. during control periods. Distension of the left atrium led within 2 min to a fall in plasma AVP concentration which reached a steady lower value within 4 min. After cessation of atrial distension the AVP concentration returned to pre-distention values within 4 min. Cooling the cervical vagosympathetic nerves to 8-10 degrees C led to a rise in plasma AVP concentration. Atrial distension during cooling of the vagi resulted in a further increase of plasma AVP concentration.
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000097:blood*; D016275:Atrial Function; D001794:Blood Pressure; D003080:Cold Temperature; D004106:Dilatation; D004285:Dogs; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D013997:Time Factors; D014630:Vagus Nerve / Q000502:physiology
chemical_list: D001127:Arginine Vasopressin