N1 latency following acute pure-tone trauma.
The latency of the N1 component of tone burst evoked compound action potentials was examined in chinchilla following acute pure-tone trauma. At and below the trauma frequency (4 kHz) the N1 latency at threshold generally increased, while above the trauma frequency it decreased; tonotopically paralleling pitch shifts observed in humans following pure-tone trauma. When N1 latency at threshold is considered across animals as a linear function of dB SPL at threshold, after trauma a high degree of linear correlation was found at 6 and 8 kHz, while a low degree of linear correlation was found at 4 kHz. An interpretation and the significance of the data are discussed.
D000818:Animals; D001309:Auditory Threshold / Q000502:physiology; D002682:Chinchilla; D003051:Cochlea / Q000503:physiopathology; D005072:Evoked Potentials, Auditory; D006317:Hearing Loss, Noise-Induced / Q000503:physiopathology*; D008144:Loudness Perception / Q000502:physiology; D010898:Pitch Perception / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*