title: [Effect of molsidomine on cardiac function in experimental transitory coronary insufficiency].
abstract: Increased resistance of the heart to acute transitory coronary insufficiency under conditions of prophylactic use of molsidomin was demonstrated in experiments on dogs and rats. The agent prevents electric destabilization of the heart. Reduction of pre- and postexertion of the heart is one of the main factors of the protective action of molsidomin. It is suggested that the drug may be included in the complex of measures used in the treatment of patients suffering from anginal and anginal-arrhythmic forms of stable and unstable angina pectoris.
mesh_terms: D000208:Acute Disease; D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy*; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005260:Female; D006321:Heart / Q000187:drug effects*; D008297:Male; D008981:Molsidomine; D009025:Morpholines / Q000627:therapeutic use*; D009200:Myocardial Contraction / Q000187:drug effects; D010069:Oxadiazoles / Q000627:therapeutic use*; D051381:Rats; D013558:Sydnones / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D009025:Morpholines; D010069:Oxadiazoles; D013558:Sydnones; D008981:Molsidomine
vernacular_title: Vliianie mol'sidomina na funktsiiu serdtsa pri éksperimental'noĭ tranzitornoĭ koronarnoĭ nedostatochnosti.