delta-Aminolevulinate synthase isozymes in the liver and erythroid cells of chicken.
Antibodies raised against the purified chicken liver delta-aminolevulinate synthase showed a partial cross-reactivity with the chicken erythroid delta-aminolevulinate synthase. delta-Aminolevulinate synthase synthesized in vitro using polysomes from erythroid cells showed a subunit molecular weight of 55,000, whereas the enzyme synthesized in vitro using liver polysomes had a subunit molecular weight of 73,000. delta-Aminolevulinate synthase isolated from mitochondria of erythroid cells showed a molecular weight of 53,000, while the enzyme in liver mitochondria had a value of 65,000. These observations imply that the erythroid delta-aminolevulinate synthase differs from the hepatic enzyme.
D000624:5-Aminolevulinate Synthetase / Q000276:immunology / Q000302:isolation & purification*; D000818:Animals; D002474:Cell-Free System; D055598:Chemical Phenomena; D002621:Chemistry; D002645:Chickens; D004912:Erythrocytes / Q000201:enzymology*; D007106:Immune Sera; D007120:Immunochemistry; D007527:Isoenzymes / Q000302:isolation & purification*; D008930:Mitochondria, Liver / Q000201:enzymology*; D008970:Molecular Weight; D011817:Rabbits
D007106:Immune Sera; D007527:Isoenzymes; D000624:5-Aminolevulinate Synthetase