Serological cross-reaction and cross-protection in guinea pigs infected with Rickettsia rickettsii and Rickettsia montana.
Antisera produced in guinea pigs inoculated with Rickettsia rickettsii or Rickettsia montana were cross-reactive but sufficiently specific to identify the primary infecting agent. Guinea pigs immunized with R. montana were protected from fatal infection with R. rickettsii, although a few (25%) developed mild fever of short duration.
D000818:Animals; D000917:Antibody Formation; D003429:Cross Reactions; D006168:Guinea Pigs; D007114:Immunization; D008297:Male; D012282:Rickettsia Infections / Q000276:immunology*