title: Overwhelming postsplenectomy infection (OPSI): the clinical syndrome.
abstract: Critical examination of the infectious risk following splenectomy raises questions about several widely held notions. True hazard of OPSI is difficult to quantify and probably underestimated, susceptibility is life-long, questionably altered by splenosis, and persists despite penicillin prophylaxis and vaccination against common pneumococcal serotypes.
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D011008:Pneumococcal Infections / Q000175:diagnosis*; D011183:Postoperative Complications; D012306:Risk; D013156:Splenectomy / Q000009:adverse effects*; D013577:Syndrome