Clones of MRC-C cells may be superior to the parent line for the culture of 229E-like strains of human respiratory coronavirus.
A clone was selected from the MRC-C continuous heteroploid cell line which was significantly better than MRC-C for the culture of human respiratory coronavirus (HCV) 229E, strain LP. Such clones could prove generally useful for the isolation of HCV-229E from clinical specimens, and for the propagation and assay of laboratory adapted strains.
D002999:Clone Cells / Q000382:microbiology*; D003332:Coronaviridae / Q000302:isolation & purification*; D004622:Embryo, Mammalian; D006801:Humans; D008168:Lung; D014776:Virus Cultivation / Q000379:methods*