Treatment of schistosome-induced glomerulonephritis. A case report and review of the literature.
A patient with membranoproliferative glomerulonephritis and renal dysfunction caused by Schistosoma mansoni was treated with oxamniquine. High levels of circulating immuno-complexes returned to normal following treatment, although renal function for the long term was unchanged. Specific antischistosomal therapy may be of partial benefit to patients with this disease.
D000328:Adult; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D010073:Oxamniquine / Q000627:therapeutic use; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000188:drug therapy / Q000473:pathology
D010073:Oxamniquine