125I-anti-insulin receptor Fab is internalized by cultured human lymphocytes.
When 125I-anti-insulin receptor Fab components are prepared from serum IgG, this univalent material binds to the surface of cultured human lymphocytes and is subsequently internalized by the cell in an identical fashion to the divalent IgG and to 125I-insulin itself.
D000936:Antigen-Antibody Complex; D000954:Antigens, Surface / Q000032:analysis; D002478:Cells, Cultured; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000276:immunology*; D007700:Kinetics; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism; D011972:Receptor, Insulin / Q000276:immunology*
D000936:Antigen-Antibody Complex; D000954:Antigens, Surface; D007140:Immunoglobulin Fab Fragments; D011972:Receptor, Insulin