Midgut carcinoid tumor with carcinoid heart disease. Its presence in the absence of hepatic metastases--a case report.
A 56-year-old man with a midgut carcinoid tumor had extensive metastatic involvement of lymphatic spaces and carcinoid heart disease. Unlike similar previously reported cases with carcinoid heart disease, hepatic metastases and history of the carcinoid syndrome were absent in this patient. Tumor involvement of cardiac lymphatic spaces may have been responsible for the development of carcinoid heart disease due to a local fibrogenic effect similar to the extensive fibrosis associated with tumor seen within the abdominal cavity at autopsy.
D006338:Heart Neoplasms / Q000556:secondary; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D007080:Ileocecal Valve; D007082:Ileum / Q000473:pathology; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000473:pathology*; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology