Relation between ionised calcium and pH in infants with acute acid-base disturbances.
Plasma ionised calcium, [Ca2+], and pH were negatively correlated in 21 infants with disturbed acid-base homeostasis. The slopes of the individual regression lines indicated a mean decrease in [Ca2+] of 42% per pH increase. (Mean delta log[Ca2+]/delta pH = -0.184, SEM = 0.050, p less than 0.001). The value was not significantly different from the relation between [Ca2+] and pH in vitro, when whole blood or plasma was equilibrated with CO2-air mixtures. pH and [Ca2+] must be measured and considered together to allow a proper interpretation of the result.
D000137:Acid-Base Imbalance / Q000097:blood*; D001769:Blood; D002118:Calcium / Q000097:blood*; D002413:Cations, Divalent; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008297:Male
D002413:Cations, Divalent; D002118:Calcium