title: Contrast media and enzyme inhibition. I. Cholinesterase.
abstract: Cholinergic mechanisms, activated by the inhibition of the acetylcholine hydrolysing enzyme cholinesterase, may be responsible for many of the adverse effects of intravascular radiological contrast media. The relative cholinesterase-inhibiting activities of several conventional and new contrast media have been measured and significant differences are found. Some of the possible implications of these differences are discussed.
mesh_terms: D000818:Animals; D002800:Cholinesterase Inhibitors; D003287:Contrast Media / Q000494:pharmacology* / Q000633:toxicity; D007455:Iodine / Q000032:analysis; D007928:Lethal Dose 50; D051379:Mice
chemical_list: D002800:Cholinesterase Inhibitors; D003287:Contrast Media; D007455:Iodine