Cyanide encephalopathy following therapy with sodium nitroprusside: report of a case.
Bilateral necrosis of the globus pallidus was observed in a 43-year-old man who had received treatment for malignant hypertension with sodium nitroprusside. Cyanide released from sodium nitroprusside may have caused the pallidal lesions in the presence of deranged liver function and episodes of hypoxia.
D000328:Adult; D002544:Cerebral Infarction / Q000139:chemically induced / Q000473:pathology; D003486:Cyanides / Q000506:poisoning*; D005292:Ferricyanides / Q000009:adverse effects*; D005917:Globus Pallidus / Q000473:pathology*; D006801:Humans; D008297:Male; D009336:Necrosis / Q000139:chemically induced; D009599:Nitroprusside / Q000009:adverse effects*
D003486:Cyanides; D005292:Ferricyanides; D009599:Nitroprusside