Plant anticancer agents. XXVI. Constituents of Peddiea fischeri.
The in vitro P-388 lymphocytic leukemia activity of the chloroform-soluble fraction of the roots of Peddiea fischeri (Thymelaceaceae) was found to be due principally to the quinone 2,6-dimethoxybenzoquinone (2,6-DMBQ), and to a lesser extent the two coumarins daphnoretin and umbelliferone. This is the first report of the occurrence of 2,6-DMBQ in the family Thymelaeaceae. The occurrence of 2,6-DMBQ in higher plants is reviewed.
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D002478:Cells, Cultured; D002845:Chromatography; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D010946:Plants, Medicinal / Q000032:analysis*
D000972:Antineoplastic Agents, Phytogenic