The nucleus basalis in Alzheimer's disease: cell counts and cortical biochemistry.
The cell density in the Nucleus Basalis in six patients with clinical and histological evidence of Alzheimer's disease and reduced choline acetyltransferase activity in frontal and temporal cortex was found to be in approximately 50% of the cell count in five control subjects.
D000368:Aged; D000544:Alzheimer Disease / Q000201:enzymology / Q000473:pathology*; D002452:Cell Count; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D003704:Dementia / Q000473:pathology*; D005260:Female; D005625:Frontal Lobe / Q000201:enzymology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009847:Olivary Nucleus / Q000473:pathology*; D013702:Temporal Lobe / Q000201:enzymology*
D002795:Choline O-Acetyltransferase