Brief clinical report: Graves disease in a patient with the del(18p) syndrome.
We report the first known patient with a del(18p) and Graves disease. This deletion has previously been reported to be associated with autoimmune thyroid disease and, perhaps, with inborn errors of thyroxin biosynthesis. We present the clinical and histological information on this patient and review the literature in an attempt to clarify the relationship between abnormalities of chromosome 18 and thyroid disease.
D000293:Adolescent; D001327:Autoimmune Diseases / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics*; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002902:Chromosomes, Human, 16-18; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000235:genetics* / Q000628:therapy; D006801:Humans; D013965:Thyroidectomy; D013974:Thyroxine / Q000097:blood
D013974:Thyroxine