[Cutaneous manifestations of thrombocythaemia associated with myelofibrosis in a patient suffering from psoriasis and treated by PUVA (author's transl)].
Cutaneous manifestations of thrombocythaemia are caused by vascular lesions, either haemorrhagic or thrombotic, affecting above all the microcirculation of the extremities. The authors report a case of thrombocythaemia associated with myelofibrosis discovered by ischaemic lesions on the toes which appeared at the beginning of PUVA therapy for psoriasis. The type of vascular lesions generally depends on the platelet count. In the presence of these cutaneous manifestations, the determination of both platelet counts and functions may orient the diagnosis toward a myeloproliferative syndrome.
D000328:Adult; D005260:Female; D011564:Furocoumarins / Q000627:therapeutic use*; D006801:Humans; D008833:Microcirculation; D010778:Photochemotherapy / Q000009:adverse effects*; D055728:Primary Myelofibrosis / Q000150:complications*; D011565:Psoriasis / Q000188:drug therapy*; D012883:Skin Ulcer / Q000209:etiology*; D013921:Thrombocytopenia / Q000209:etiology*; D014034:Toes / Q000098:blood supply
D011564:Furocoumarins
Manifestations cutanées d'une thrombocytémie associée à une myélofibrose chez une patiente psoriasique traitée au PUVA.