Neonatal sex-steroid hormones and timidity in 6-18-month-old boys and girls.
Five sex-steroid hormones (testosterone, androstenedione, estradiol, estrone, and progesterone) are assayed in umbilical cord blood. Timidity is assessed in home and laboratory observations by reactions to a range of novel toys in children from 6 to 18 months of age. Significant short- (1 week) and long- (several months) term stability in timidity is demonstrated. Girls have higher mean scores on observed timidity than do boys in 2 of the 3 samples tested. An across-age timidity score is computed which shows significant correlations with neonatal progesterone, testosterone, and estradiol for boys, but is not significantly predicted by hormone concentrations in girls.
D000735:Androstenedione / Q000097:blood; D004958:Estradiol / Q000097:blood; D004970:Estrone / Q000097:blood; D005260:Female; D005312:Fetal Blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000523:psychology*; D008137:Longitudinal Studies; D008297:Male; D011374:Progesterone / Q000097:blood; D012737:Sex Factors; D012919:Social Behavior; D013739:Testosterone / Q000097:blood
D012739:Gonadal Steroid Hormones; D004970:Estrone; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol