Differences in the content and turnover of noradrenaline in rat heart atria and ventricles and circadian-phase-dependency.
In light-dark-synchronized male rats the levels of noradrenaline in heart atria were about 3 times that found in heart ventricles. Noradrenaline turnover rate which were about 8-9 fold greater for the atria than for the ventricles displayed a circadian-phase-dependency with increased rates in the dark period in both parts of the rat heart.
D000818:Animals; D005406:Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide / Q000494:pharmacology; D002940:Circadian Rhythm; D004299:Dopamine beta-Hydroxylase / Q000037:antagonists & inhibitors; D006325:Heart Atria / Q000378:metabolism; D006352:Heart Ventricles / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D005406:Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine