Opportunistic Trichosporon pneumonia. Association with invasive aspergillosis.
Two severely immunocompromised patients suffered extensive pulmonary infection with Trichosporon cutaneum (T beigelii) and Aspergillus species. In one patient, the T cutaneum demonstrated yeast forms in tissue sections. The other patient had T cutaneum fungemia prior to death, and examination of lung tissue demonstrated both yeast and hyphal forms. To our knowledge, these patients are the first described with polymycotic infection involving T cutaneum and Aspergillus species. Trichosporon cutaneum must be added to Candida, Torulopsis, and Cryptococcus species as a cause of visceral opportunistic yeast infection.
D000368:Aged; D001228:Aspergillosis / Q000150:complications*; D005260:Female; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications / Q000382:microbiology*