Male mouse submaxillary gland secretes highly toxic proteins.
Submaxillary gland saliva induced by phenylephrine from male mice was highly toxic to guinea-pigs, rats and hamsters, whereas the toxicity was relatively low to mice. One of the toxic components in the saliva was isolated as a kallikrein-like enzyme.
D000818:Animals; D006224:Cricetinae; D006168:Guinea Pigs; D007610:Kallikreins / Q000302:isolation & purification; D008297:Male; D051379:Mice / Q000378:metabolism*; D010656:Phenylephrine / Q000494:pharmacology; D011506:Proteins / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D012463:Saliva / Q000032:analysis*; D013363:Submandibular Gland / Q000378:metabolism*; D014118:Toxins, Biological / Q000378:metabolism*
D011506:Proteins; D014118:Toxins, Biological; D010656:Phenylephrine; D007610:Kallikreins