Experimental pulmonary emphysema: its induction in rats by leuko-elastase extracted from purulent sputum.
Pulmonary emphysema was induced in rats by leuko-elastase extracted from purulent sputum, with the aim of throwing light on the part played by the elastolytic activity in the pathogenesis of pulmonary emphysema. A brief review of the pertaining literature is presented.
D000328:Adult; D000336:Aerosols; D000818:Animals; D001991:Bronchitis / Q000097:blood; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008168:Lung / Q000473:pathology; D008297:Male; D010196:Pancreatic Elastase / Q000008:administration & dosage / Q000494:pharmacology*; D011650:Pulmonary Alveoli / Q000473:pathology; D011656:Pulmonary Emphysema / Q000139:chemically induced*; D051381:Rats; D013183:Sputum / Q000032:analysis
D000336:Aerosols; D010196:Pancreatic Elastase