Cardiovascular changes in elicited by vagal gastric afferents in the rat.
Cardiovascular changes elicited by gastric distension in the urethane anaesthetized rat are described. Heart rate changes were mediated via a vago-vagal pathway with 'in-series' tension receptors in the stomach wall providing the afferent input and cholinergic cardio-inhibitory fibres forming the efferent pathway. Blood pressure changes occurred independently of the heart rate changes; the main afferent pathway was again vagal but the efferent outflow was non-cholinergic and probably sympathetic.
D000818:Animals; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D008465:Mechanoreceptors / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology; D010812:Physical Stimulation; D051381:Rats; D013270:Stomach / Q000294:innervation*; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology*