Why do surgical packs cause peritoneal adhesions?
Our experiments in the Porton rat have shown that the foreign debris from surgical sponges left in the peritoneal cavity after use is not the cause of peritoneal adhesions. Instead, the abrasive effect of introducing the sponge produces mesothelial trauma. This is the stimulus for an inflammatory response, followed by adherence of adjacent involved peritoneal surfaces. Adhesions formation did not occur between the abraded peritoneal surfaces of mobile intraabdominal viscera, which suggests that intestinal motility in the early postoperative period is important in the prevention of adhesions.
D000818:Animals; D005260:Female; D007431:Intraoperative Complications; D008297:Male; D010532:Peritoneal Diseases / Q000209:etiology* / Q000473:pathology; D010537:Peritoneum / Q000293:injuries; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology; D051381:Rats; D013630:Tampons, Surgical; D000267:Tissue Adhesions