[Cerebrospinal fluid and blood kinins of patients with cerebral circulatory disorders].
The kallikrein-kinin system components were examined in the cerebrospinal fluid and the blood of patients with acute cerebral circulation disorders at various intervals after the vascular episode. A considerable increase in the content of all the substances being examined in the patients' cerebrospinal fluid was shown, this increase being not dependent on the stroke character. An activation of the kallikrein-kinin system was observed in the blood plasma within the first 20 days after the vascular episode. In young patients, these changes were more pronounced. The changes in the kallikrein-kinin system components, along with those of other vasoactive substances may take a certain part in the pathogenetic mechanisms of the cerebral stroke.
D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D002561:Cerebrovascular Disorders / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism; D002546:Ischemic Attack, Transient / Q000378:metabolism; D007610:Kallikreins / Q000032:analysis* / Q000037:antagonists & inhibitors; D008875:Middle Aged; D011288:Prekallikrein / Q000032:analysis*; D013997:Time Factors
D011288:Prekallikrein; D007610:Kallikreins
Kininy likvora i krovi u bol'nykh s narusheniiami mozgovogo krovoobrashcheniia.