[The radiofibrinogen test and the fibrinsplit product test in the diagnosis of deep veinous thrombophlebitis during radiotherapy. A contribution to the evaluation for silent acute thrombophlebitis (author's transl)].
The radiofibrinogen test is especially useful for the diagnosis of deep veinous thrombophlebitis in the legs in patients undergoing radiotherapy for gyanecological cancer. In 62 patients, 6 deep veinous thrombophlebitis were observed during 124 radium insertions in conjunction with preventive administration of anti-coagulants. The most important test for the early coagulation physiologic diagnosis of deep leg thrombophlebitis is the test for fibrinogen and fibrinsplit products. A suitable procedure is the Latex-agglutination test which is technically uncomplicated. If deep leg vein thrombophlebitis is found by the radiofibrinogen test, the fibrinsplit products always show at least a fourfold increase.
D000368:Aged; D001918:Brachytherapy / Q000009:adverse effects; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen; D006801:Humans; D008875:Middle Aged; D011867:Radioisotope Teletherapy / Q000009:adverse effects; D013927:Thrombosis / Q000175:diagnosis* / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy; D014594:Uterine Neoplasms / Q000532:radiotherapy
D003037:Cobalt Radioisotopes; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen
Radiofibrinogentest und Fibrinogenspaltprodukte zum Nachweis von Beinvenenthrombosen im Rahmen der Radium-behandlung. Ein Beitrag zur Erkennung einer akuten, klinisch symptomlosen Thrombose.