[Clinical results of the treatment of ovarian carcinoma following 16 years of experience with the chemotherapy resistance test (author's transl)].
A prospective study on the results of chemotherapy selected by the treatment chemotherapy resistance test of Limburg an Krahe (oncobiogram) of 191 cancers of the ovary from the same department from the years 1962-1978 is presented. In 152 cases (79.6%) surgical or radio-therapy was impossible or insufficient because of the advanced spread of the tumour (T4 of FIGO 3 and 4). Nevertheless in the hopeless state T4 Nx M1b (N = 89) a two years survival rate of 58% was obtained following the selective treatment according to the oncobiogram compared to 28% two years survival in blind chemotherapy. The five year survival rate was 38% compared to 18%. The total five years survival rate of all patients was 25% in a series with 80% inoperable cases. The advantages of chemotherapy following the oncobiogram with the chemotherapy resistance test compared to treatment after other testing methods or compared to blind chemotherapy are described and discussed in detail.
D000970:Antineoplastic Agents / Q000009:adverse effects; D004351:Drug Resistance; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D011446:Prospective Studies
D000970:Antineoplastic Agents
16jährige klinische Ergebnisse in der Behandlung des Ovarialkarzinoms nach dem Chemotherapie Resistenztest.