[Prenatal sex determination via GBN saliva test. A comparison with the results of prenatal chromosomal analysis].
In 114 pregnant women the results of the GBN saliva test were compared with the results of sex determination by prenatal chromosomal analysis. GBN test results predicting boys corresponded in 40,7% of the cases with male karyotypes, whereas test results predicting girls corresponded in 56,5% with female karyotypes. Mean age of the women tested was 35,9 +/- 3,6 years. The test results in women aged 35 or younger did not show a better correlation with the chromosomal sexing than in older women (46,5% and 48,4%). Saliva tests performed in the 16th to 20th week of gestation corresponded to the same extent with the chromosomal sex of the fetuses as those performed in the 21st to 32nd week of gestation (48,5% and 46,2%). The mode of ascertainment of the pregnant women and other factors possibly influencing the results are discussed. It is concluded that the GBN saliva test is not suitable for prenatal sex prediction in women of the age group investigated.
D000328:Adult; D000649:Amniocentesis; D000728:Androgens / Q000032:analysis; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008423:Maternal Age; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D012463:Saliva / Q000032:analysis*; D012732:Sex Determination Analysis
D000728:Androgens
Pränatale Geschlechts-bestimmung durch den GBN-Speicheltest. Ein Vergleich mit den Ergebnissen der pränatalen Chromosomendiagnostik.