Childhood chronic relapsing polyneuropathy: dramatic improvement following plasmapheresis.
We present clinical data on two boys with chronic relapsing polyneuropathy. Their recurrent episodes of weakness had produced marked disability which was unresponsive to continuous prednisone therapy. Plasmapheresis produced dramatic improvement in muscle strength and functional ability. The remissions induced have been sustained despite withdrawal of steroid therapy.
D000293:Adolescent; D002648:Child; D002908:Chronic Disease; D006801:Humans; D008297:Male; D010956:Plasmapheresis; D011115:Polyneuropathies / Q000503:physiopathology / Q000628:therapy*; D012008:Recurrence