Exclusions and attributions of paternity: practical experiences of forensic genetics and statistics.
The Swedish State Institute for Blood Group Serology is a central government laboratory handling all blood typing in paternity cases in Sweden, each year testing 1,500-2,000 cases using about 13 polymorphisms. Of the accused men, 35%-40% are nonfathers, but in one-man cases (about 78% of all cases), approximately 75% are the true fathers. Exclusions appear to be distributed as expected from allele frequencies, and the paternity probability of nonexcluded men is assessed with a Bayesian approach. Some cases are retested in extended investigations which raise theoretical exclusion capability from about 87% to about 99%. Both the results of extended investigations and the theoretical consideration of the distribution of paternity probabilities support the use of such positive statistical evidence for the attribution of paternity.
D000328:Adult; D001499:Bayes Theorem; D001789:Blood Group Antigens / Q000235:genetics*; D002648:Child; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic; D013223:Statistics as Topic
D001789:Blood Group Antigens; D005819:Genetic Markers