[Flow-volume curves in healthy children and adolescents 10-19 years of age. Reference values and lower limits of the normal].
In 477 healthy children and adolescents (247 boys and 230 girls, aged 10 to 19 years), we measured the vital capacity (VC), the forced expiratory volume in one second (FEV1), the flow between 25 and 75% of expired forced vital capacity (FEF25-75) and the forced expiratory flows when 75, 50 and 25% of forced vital capacity remain to be expired (FEF75, FEF50, FEF25), in order to determine reference values and lower limits of the normal. Regression functions were calculated for girls and boys separately. The best correlations for pulmonary volumes and flows were obtained by taking into account simultaneously height and age in girls, height, age and weight in boys. Power function is the model of regression that fits our data the best. The regression functions determined, as well as the lower limits of the normal and the residual standard deviations, are given by sex for each of the variables measured. These results are discussed and compared with those in literature. They concern clinicians (identification of "abnormal" subjects) and epidemiologists (prevalence of ventilatory troubles, comparison of different populations), and can be used in adolescents of the same age groups.
D000293:Adolescent; D000328:Adult; D001827:Body Height; D001835:Body Weight; D002648:Child; D005260:Female; D005540:Forced Expiratory Flow Rates; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008449:Maximal Expiratory Flow-Volume Curves; D012016:Reference Values; D012737:Sex Factors; D013147:Spirometry; D014797:Vital Capacity
Courbe débit-volume chez des enfants et adolescents sains de 10 a 19 ans. Valeurs de référence et limites inférieures de la normale.