Recall failure following successful generation and recognition of responses by alcoholic Korsakoff patients.
Amnesic Korsakoff patients and controls were presented with twelve words, each shown individually in the presence of a weak associate. They were then asked to freely associate to 12 other words that were strong associates of the to-be-remembered (TBR) words. The Korsakoff patients generated, and were able to recognize, as many of the TBR words as the controls. Yet, in spite of this recognition ability, these same patients were subsequently unable to recall the critical TBR words when the weak cues were again presented. A follow-up study found that the same recognition results could be obtained with Korsakoffs months after initial presentation suggesting that the patients might initially have "recognized" the most highly associated words simply because they represented the most probable choices. Intermediate association prompts failed to generate correct responses. It was hypothesized that the Korsakoff patients cannot restructure their semantic associative hierarchy during input in such a way as to become sensitized to other than the strongest associates as prompts during recall.
D000425:Alcohol Amnestic Disorder / Q000523:psychology*; D001244:Association; D003463:Cues; D006801:Humans; D008297:Male; D008568:Memory; D011939:Mental Recall; D008875:Middle Aged; D012660:Semantics