Influence of alkaline pH on the effectiveness of sodium fluoride dentifrices.
Two similar sodium fluoride dentifrices, one neutral and one alkaline, were compared to a placebo for clinical effectiveness in reducing caries. The neutral dentifrice contained 35% less soluble fluoride than the alkaline dentifrice. Both fluoride dentifrices were significantly effective but were not different from each other.
D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010919:Placebos; D012969:Sodium Fluoride / Q000627:therapeutic use*; D014099:Toothbrushing
D003802:Dentifrices; D010919:Placebos; D012969:Sodium Fluoride; D005459:Fluorides