Flow-volume curves in children in health and disease.
Pulmonary function studies were done in 136 children (5.5-17 yr old) of whom 39 had allergic type asthma, 26 chronic bronchorrhea, and 13 mucoviscidosis; the remaining 58 subjects were healthy. The children having respiratory problems were studied when they were clinically free from wheezing and pulmonary infection. Measurements of forced expiration were made with a pneumotachograph; the data were stored on a magnetic tape and analysed with a Hewlett-Packard programmed computer. Standards for the different ventilatory parameters were established for the healthy children. A step by step discriminant linear analysis of the data and application of the Kolmogorov-Smirnov test demonstrated that V25, V50 and MMEF measurements were the best discriminating parameters of pulmonary function abnormalities in the respiratory problem children.
D000293:Adolescent; D001249:Asthma / Q000503:physiopathology; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D003201:Computers; D003550:Cystic Fibrosis / Q000503:physiopathology; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008171:Lung Diseases / Q000503:physiopathology*; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D009093:Mucus / Q000378:metabolism; D010366:Peak Expiratory Flow Rate; D012123:Pulmonary Ventilation; D014797:Vital Capacity