Chromosome aberrations and prognosis in preleukaemia.
24 patients with preleukaemia were cytogenetically studied by the G-banding staining technique. All patients developed later frank acute non-lymphocytic leukaemia and died. 13 patients had a completely normal karyotype (NN-patients) with a median survival time of 8 months. 6 patients had both normal and abnormal metaphases (AN-patients) with a median survival time of 18.5 months, while 5 patients had abnormal metaphases only (AA-patients) with a median survival time of 3 months.
D000368:Aged; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000235:genetics / Q000401:mortality; D007948:Leukemia, Monocytic, Acute / Q000235:genetics / Q000401:mortality; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000401:mortality; D008297:Male; D008677:Metaphase; D008875:Middle Aged; D011289:Preleukemia / Q000235:genetics* / Q000401:mortality; D011379:Prognosis