Relationship between dimethylnitrosamine metabolism or activation and its ability to induce liver necrosis in rats.
D000818:Animals; D001711:Biotransformation / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology; D003538:Cystamine / Q000494:pharmacology; D004128:Dimethylnitrosamine / Q000378:metabolism* / Q000633:toxicity; D004155:Diphenhydramine / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D009336:Necrosis; D011720:Pyrazoles / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology; D051381:Rats
D011720:Pyrazoles; D011725:Pyridines; C013109:metapyrone; D004155:Diphenhydramine; D004128:Dimethylnitrosamine; D003538:Cystamine; D002746:Chlorpromazine