Recovery of body weight following starvation or food restriction in rats.
Recovery of body weight and food intake have been studied and compared after a 25% weight loss produced by total starvation in one group of rats or by food restriction in a second group. It was shown that rats in both groups returned to their initial body weight within the same time on the average, but the hyperphagia observed during the recovery phase was significantly higher in restricted than in starved rats. In the former, the increase of food intake fully accounted for the weight gain. On the contrary, the recovery of body weight in previously starved rats involved both hyperphagia and a long lasting persistence of the fasting hypometabolism. In addition, it was shown that in those rats the higher the contribution of hypometabolism the longer the recovery. Starvation diabetes was higher in starved than in restricted rats and might be one factor which impairs weight regulation through hyperphagia after a weight loss induced by food deprivation.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D001835:Body Weight; D004327:Drinking Behavior / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D005508:Food Deprivation / Q000502:physiology*; D008657:Metabolic Clearance Rate; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000503:physiopathology*
D001786:Blood Glucose