A pseudoepidemic of pulmonary fungal infections related to fiberoptic bronchoscopy.
During a three-week period a pseudoepidemic of fungal infections occurred involving patients from two different services. Trichosporon cutaneum and a Penicillium species were isolated from bronchial washings and sputa obtained after fiberoptic bronchoscopy on eight clinically uninfected patients. Investigation revealed contamination of cocaine solutions used for topical anesthesia during bronchoscopy. Contamination is thought to have occurred during preparation of the solutions by pharmacy personnel. Revision of techniques used in formulating and dispensing the solutions resulted in cessation of the pseudoepidemic.
D000368:Aged; D001999:Bronchoscopy / Q000009:adverse effects*; D003428:Cross Infection / Q000453:epidemiology*; D003454:Cryptococcus / Q000302:isolation & purification*; D004340:Drug Contamination; D005189:False Positive Reactions; D005260:Female; D005336:Fiber Optic Technology; D006746:Hospital Bed Capacity, 500 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000453:epidemiology; D010407:Penicillium / Q000302:isolation & purification*; D010607:Pharmacy Service, Hospital; D011014:Pneumonia / Q000453:epidemiology; D013183:Sputum / Q000382:microbiology*; D014768:Virginia