[The cardiac situation of newborn children after long-term tocolysis with fenoterol (author's transl)].
516 newborn children were subject to a thorough cardiac and neurological test program after a long-term tocolysis with Fenoterol with and without a supplementary medication of Verapamil. No symptoms of a myocardial damage caused by the drug appeared neither in the electrocardiogram nor by means of lab-chemical parameters such as CK-MB, Serum-Myoglobin and CK-B. Except for premature children, no significant neurological characteristics were found either. Due to the low quantity of Fenoterol passing through the placenta and based on the minimum cumulation of Fenoterol in the fetal tissue, especially in the fetal myocardium, a tocolysis does not seem to have any significantly dangerous fetal effects, if control parameters are strictly adhered to. The endeavoured therapeutical objective, namely the prevention of premature labour, thus justifies the application of the betasympathomimetic Fenoterol.
D000293:Adolescent; D000328:Adult; D004562:Electrocardiography; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use*; D005318:Fetal Heart / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy
D004983:Ethanolamines; D005280:Fenoterol
Zur kardialen Situation von Neugeborenen nach Lang-zeittokolyse mit Fenoterol.