[Risks and prognosis for success of a pregnancy following replacement of a heart valve (author's transl)].
After replacement of a heart valve a pregnancy is possible in the complaint categories I and II. Treatment with anti-coagulation is necessary for plastic heart valves. To avoid teratogenic effects the early pregnancy is best managed with heparin although stillbirth and early intra-uterine death are more common than with Marcumar. A treatment with heparin 10,000 units subcutaneously twice throughout all of the pregnancy is recommended. According to the literature 2/3 of the pregnancy with anti-coagulation result in the normal delivery of a healthy infant. Of 202 women in the reproductive age group with artificial heart valves, 150 were followed by a questionnaire. 25 women desired children. 10 women had pregnancies. 1 had two pregnancies, 1 had three pregnancies, 3 healthy infants were born.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis*; D011379:Prognosis
D000925:Anticoagulants
Risiken und Erfolgsaussichten einer Schwangerschaft nach Herzklappenersatz.