[Report of 22 cases of congenital adrenal genital syndrome (AGS) observed in the reproductive age group (author's transl)].
22 adolescent and adult female patients - 15 to 37 years old - with the Congenital Adrenogenital Syndrome (AGS) were examined. In only 7 cases the disease was diagnosed immediately after birth. Among 16 patients, which had already undergone a reconstructive operation of the external genitalia, only 5 were satisfied with its cosmetic and functional results. 11 women could not do a sexual intercourse due to the malformed external genitalia. Menarche occurred spontaneously in only 10 cases under cortisone-therapy. At the time of investigation only 4 patients had regular menstrual-cycles. Adolescents suffering from AGS should be referred to a pediatric-gynecologist not later than puberty to assure an individual guidance relating to menstruation, surgical intervention, sexual-life and fertility.
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D000328:Adult; D000367:Age Factors; D003348:Cortisone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008572:Menarche; D012725:Sexual Behavior
D003348:Cortisone
Das kongenitale adreno-genitale Syndrom (AGS) im geschlechtsreifen Alter. Bericht über 22 Fälle.