[Cytophotometric study of the DNA content of the liver of rats poisoned with N-nitrosomorpholine].
The evolution of ploidy of liver cells during malignant transformation by N-nitrosomorpholine was studied cytophotometrically. It was observed an increased ploidy that was due to the toxic action of the product and lasted six weeks, and a gradual return to normal values after the administration of the drug was discontinued.
D000818:Animals; D004247:DNA / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000187:drug effects; D008297:Male; D009602:Nitrosamines / Q000494:pharmacology / Q000633:toxicity*; D011003:Ploidies / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains
D009602:Nitrosamines; C002741:N-nitrosomorpholine; D004247:DNA
Estudio citofotométrico del contenido en ADN en el hígado de ratas intoxicadas con N-nitrosomorfolina (NNM).