Comparison between the complement fixation test LBCF-H100-TTE, IHAT and IgM-IFAT performed on pure IgM fractions in acute acquired and congenital toxoplasmosis.
The use of a gel filtration method allowed us to obtain pure IgM fractions to be tested for specific Toxoplasma serology. The good correlation found in our series between IgM-IFAT and LBCF-H100-TTE performed on pure IgM fractions suggests that LBCF-H100-TTE may be another useful serological test for detection of IgM antibodies although false negative results might occur when LBCF-H100-TTE is performed on IgM fractions of cord sera.
D000208:Acute Disease; D000328:Adult; D000906:Antibodies / Q000032:analysis; D002850:Chromatography, Gel; D003168:Complement Fixation Tests; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000276:immunology*; D014125:Toxoplasmosis, Congenital / Q000276:immunology
D000906:Antibodies; D007075:Immunoglobulin M