Effects of the resin and smoke condensate of Cannabis sativa on the oestrous cycle of the rat.
This study is concerned with variations in the oestrous cycle of the Sprague-Dawley rat following the intraperitoneal administration of maize oil solutions of Cannabis sativa resin and smoke condensate in doses of 10 and 20 mg/kg. Oestrus was shortened with doses of both the resin and the smoke condensate, whereas dioestrus was lengthened with the 20 mg/kg smoke condensate. ALso observed was a lengthening of postoestrus following the administration of 20 mg/kg of either the resin or the smoke condensate.
D000818:Animals; D002186:Cannabinoids / Q000008:administration & dosage / Q000494:pharmacology*; D002188:Cannabis; D004031:Diestrus / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004971:Estrus / Q000187:drug effects*; D005260:Female; D011247:Pregnancy; D011359:Proestrus / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012116:Resins, Plant / Q000008:administration & dosage / Q000494:pharmacology; D012906:Smoke; D013997:Time Factors
D002186:Cannabinoids; D012116:Resins, Plant; D012906:Smoke