[Coordination compounds of Pd(II) with potential antitumor activity].
The first results about the anti-neoplastic activity of Pd(II) ion coordinative compounds with complexones of the ethylenediamine-tetraacetic acid type are described. The assays employing Ehrlich ascites cancer of the mouse show that the presence of substitutes in the ethylenediamine skeleton originates important changes of the activity of such compounds.
D000818:Animals; D000970:Antineoplastic Agents / Q000032:analysis / Q000627:therapeutic use* / Q000633:toxicity; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D051379:Mice; D010165:Palladium / Q000032:analysis / Q000627:therapeutic use* / Q000633:toxicity; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D010165:Palladium
Compuestos de coordinación de Pd(II) con potencial actividad antitumoral.