Vanadate inhibits mevalonate synthesis and activates NADH oxidation in microsomes.
D000818:Animals; D004789:Enzyme Activation / Q000187:drug effects; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D066298:In Vitro Techniques; D008297:Male; D008798:Mevalonic Acid / Q000096:biosynthesis*; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D009243:NAD / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D051381:Rats; D014638:Vanadates; D014639:Vanadium / Q000494:pharmacology*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D014639:Vanadium; D009243:NAD; D014638:Vanadates; D009247:NADH, NADPH Oxidoreductases; D008798:Mevalonic Acid