[Bf groups in ankylosing spondylitis].
The phenotypes Bf were studied in 50 patients (42 men and 8 women) with definite ankylosing spondylitis and in certain of their relatives. The alleles BfF and BfS were most frequently encountered and the rare allele BfF1 in one case only. There may exist a preferential transmission of the haplotype HLA B27- Bf S. In 11 patients without B27 antigen, the distribution of the phenotypes was similar to that in a control group. It is probable that the locus Bf cannot be used as a preferential marker for ankylosing spondylitis.
D011415:Complement Factor B / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D013167:Spondylitis, Ankylosing / Q000235:genetics*
D004792:Enzyme Precursors; D011415:Complement Factor B
Groupage Bf dans la spondylarthrite ankylosante.