Hemorrhagic pancreatitis in a patient with glycogen storage disease type I.
A 17-year-old female with glycogen storage disease type I (GSD-I) died suddenly with hemorrhagic pancreatitis. She had a long-standing history of hyperlipidemia that did not respond to a regimen of frequent daytime and nocturnal intragastric feeding. Although pancreatitis is a well-known complication of hyperlipidemia, there are no reports to our knowledge of pancreatitis causing sudden death in patients with GSD-I. Pancreatitis must be added to the growing list of complications that can occur in long-term survivors with GSD-I, and should be considered when these patients present with abdominal pain.
D000293:Adolescent; D002908:Chronic Disease; D005260:Female; D005953:Glycogen Storage Disease Type I / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000209:etiology; D010195:Pancreatitis / Q000209:etiology*