[Giant cell pneumonia. Complication in one case of acute lymphoblastic leukemia (author's transl)].
A patient suffering from acute lymphoblastic leukemia, in complete remission for two years, is treated for haematologic relapse with V.P.D. and C.O.A.P. consolidation. After this treatment, develops tiredness, sleepiness, a slight fever and cough, dying some days after, of interstitial pneumonia. Post-mortem anatomic-pathological studies, show giant cell multinucleated pneumopathia, with intranuclear inclusions bodies, that in ultrastructural level resembles paramyxovirus. When this complication took place, the patient had a brother with measles, but he hasn't, the typical symptomatology of said virus disease. According to Siegel, authors point out the frequency of death due to interstitial pneumonia as a complication caused by measles in immunodeficient patients, remarking the importance of an immediate diagnosis and its' prophylaxis.
D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007223:Infant; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000188:drug therapy; D008457:Measles / Q000150:complications*; D011024:Pneumonia, Viral / Q000209:etiology*
D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents
Neumonía de células gigantes. Complicación de un caso de leucosis linfoblástica aguda.