title: [Development of periodontitis in the hamster. Quantitative macroscopic study of the accumulation of bacterial plaque and of alveolysis].
abstract: The purpose of this study was to determine the relationships between bacterial plaque accumulation and alveolar bone resorption during the progression of periodontal disease in the hamster. The results showed that control animals developed a spontaneous periodontitis characterized by a progressive increase in bacterial plaque accumulation and alveolar bone resorption. The experimental animals submitted to high carbohydrate the Keyes 2000 diet accumulated very important quantities of plaque during the experimental period (6 months) and showed important bone loss. It seemed in fact that the Keyes 2000 diet just accelerated a spontaneous phenomenon. The experimental animals developed extensive cervical caries in close relationship with bacterial plaque accumulation. The role of the high carbohydrate diet in the development of this caries is determinant since it was absent in the control animals.
mesh_terms: D000539:Alveolar Process / Q000503:physiopathology*; D000818:Animals; D001862:Bone Resorption / Q000209:etiology / Q000503:physiopathology*; D006224:Cricetinae; D003731:Dental Caries / Q000209:etiology; D003773:Dental Plaque / Q000503:physiopathology*; D004040:Dietary Carbohydrates / Q000009:adverse effects; D008297:Male; D010518:Periodontitis / Q000209:etiology / Q000503:physiopathology*
chemical_list: D004040:Dietary Carbohydrates
vernacular_title: Evolution de la parodontite chez le hamster. Etude quantitative macroscopique de l'accumulation de la plaque bactérienne et de l'alvéolyse.