title: Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals.
abstract: Human foetal adrenals have provided a rich source of steroid alcohol sulphotransferase (EC 2.8.2.-). The latter was isolated in pure form in one step by affinity chromatography on an (NH4)2SO4 cut derived from the cytosol fraction of the glands. The yield was 6-fold higher than that obtained from adult human adrenals. General properties of the enzyme are given and it appears to be identical to that obtained previously from adult human adrenals.
mesh_terms: D000311:Adrenal Glands / Q000201:enzymology*; D005333:Fetus / Q000201:enzymology; D006801:Humans; D015238:Sulfotransferases; D013466:Sulfurtransferases / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D013466:Sulfurtransferases; D015238:Sulfotransferases; C019998:dehydroepiandrosterone sulfotransferase