Sorbitol and myoinositol levels in the cerebrospinal fluid of diabetic patients.
Sorbitol and myoinositol have been measured from human cerebrospinal fluid. The normal concentrations are very small (below 100 microM/l). The detection limit of the Gas Liquid Chromatographic method was 5 microM/l. The sensitive method provided a possibility to compare quantitatively the sugar alcohol concentrations in human cerebrospinal fluid. Sorbitol concentration was increased and myoinositol concentration decreased in the cerebrospinal fluid of diabetic patients.
D003920:Diabetes Mellitus / Q000134:cerebrospinal fluid* / Q000378:metabolism; D006801:Humans; D007294:Inositol / Q000097:blood / Q000134:cerebrospinal fluid* / Q000652:urine; D012016:Reference Values; D013012:Sorbitol / Q000097:blood / Q000134:cerebrospinal fluid* / Q000652:urine
D007294:Inositol; D013012:Sorbitol