Renal size as a prognostic factor in childhood acute lymphoblastic leukemia.
A single-film intravenous pyelogram was performed on 87 children with acute lymphoblastic leukemia at presentation. The kidney size was measured and a standard deviation score based on patient height was calculated. There was a tendency of renal enlargement, with 21 patients (24%) having scores of over 1 SD and 6 (7%) over 2 SD. A trend of shorter duration of first remission with increasing renal size was shown to be statistically significant (P = 0.036). This trend was not quite statistically significant (P = 0.087) whenthe analysis was confined to 54 "better-risk" patients (WBC less than 20 X 10(9)/liter and no mediastinal mass), and was much weaker and not significant in 33 "poor-risk" patients (P = 0.62).
D002648:Child; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology*; D007945:Leukemia, Lymphoid / Q000473:pathology*; D011379:Prognosis; D012075:Remission, Spontaneous; D012306:Risk; D014567:Urography