title: Double blind controlled trial of deanol in tardive dyskinesia.
abstract: Thirty three chronic psychiatric hospital subjects with oral tardive dyskinesia were divided into three groups. The subjects were matched for severity of symptoms then randomly assigned to treatment with a placebo, 1 g deanol or 2 g deanol per day. Statistical analysis showed that after 30 days treatment, there was a significant reduction in the mean rating of the movements of the group of 11 subjects on 2 g deanol per day. Six of these subjects showed substantial reduction in movement. Further studies using this dosage of deanol are unwarranted.
mesh_terms: D000368:Aged; D003642:Deanol / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy*; D004983:Ethanolamines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004983:Ethanolamines; D003642:Deanol