title: [Results of Primary chemotherapy and Delayed Surgical Resection in Osteosarcoma (author's transl)].
abstract: Primary systemic therapy with delayed surgical intervention has been employed for the treatment of malignant bone tumours since 1977 at the Universitäts-Kinderklinik and III. Medizinische Abteilung Graz. Improved therapeutic results, as originally reported on a large number of patients at the Memorial Sloan Kettering Cancer Center (MSKCC) seem to have been attained with a small group of patients (n = 5).
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D012516:Osteosarcoma / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents; D008727:Methotrexate
vernacular_title: Erfahrungen mit der primären Chemotherapie und verzögerten extremitätenerhaltenden Operation beim Osteosarkom.