Plasma kinetics and urinary excretion of primaquine in man.
1 The kinetics of primaquine have been studied in twenty volunteers after single and multiple dose regimes. 2 The kinetic parameters were similar in glucose-6-phosphate dehydrogenase (G6PD) normal Thais, G6PD deficient Thais and in Caucasians. 3 The Caucasian subjects showed about 1% of the dose was excreted in the urine. 4 The kinetic parameters obtained from multiple dose studies in Thais were very similar to those obtained from single dose studies in Thais.
D044466:Asian People; D005953:Glycogen Storage Disease Type I / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D011319:Primaquine / Q000097:blood / Q000378:metabolism* / Q000652:urine; D044465:White People
D011319:Primaquine