[Isolation and characteristics of somatic cell hybrids of the Chinese hamster and American mink].
The paper deals with obtaining somatic cell hybrids of Chinese hamster and mink by means of inactivated Sendy virus. 39 hybrid clones segregating mink chromosomes were formed by fusing Chinese hamster cells deficient in hypoxanthine phosphoribosyliransferase with normal cells of mink. Enzyme analyses of these hybrid clones revealed that in mink genes coding lactate dehydrogenase-A, lactate dehydrogenase-B, malate dehydrogenase-NAD (soluble), 6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase are not syntenic. A possibility of successful utilization of these somatic cell hybrids for mapping mink genes is shown.
D000818:Animals; D002469:Cell Separation; D002478:Cells, Cultured; D002874:Chromosome Mapping; D006224:Cricetinae / Q000235:genetics*; D003412:Cricetulus / Q000235:genetics*; D005819:Genetic Markers; D006822:Hybrid Cells / Q000648:ultrastructure*; D007527:Isoenzymes / Q000235:genetics; D007621:Karyotyping; D008907:Mink / Q000235:genetics*
D005819:Genetic Markers; D007527:Isoenzymes
Poluchenie i kharakteristika gibridov somaticheskikh kletok kitaĭskogo khomiachka i amerikanskoĭ norki.