In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis.
Prevention of experimental allergic encephalitis in SJL/J [H-2s] mice was achieved with in vivo administration of antibody reactive with I-As gene products prior to immunization with spinal cord antigen. No protection was evident in animals that received antisera specific for I-Js gene products. Administration of antibody to I-As beginning 5 days after immunization with spinal cord antigen delayed, but did not prevent, the onset of experimental allergic encephalitis.
D000818:Animals; D000911:Antibodies, Monoclonal; D004195:Disease Models, Animal; D004660:Encephalitis / Q000276:immunology* / Q000517:prevention & control; D007112:Immunity, Maternally-Acquired; D051379:Mice; D008815:Mice, Inbred Strains; D013118:Spinal Cord Diseases / Q000276:immunology* / Q000517:prevention & control
D000911:Antibodies, Monoclonal