Arterial oxygen changes in asthmatics following histamine.
Nine patients with extrinsic bronchial asthma were challenged with increasing doses of histamine until there was a 20% fall in the forced expiratory volume in one second (FEV1). In association with the reduction in FEV1 there was a rise in the arterial oxygen blood tension except in three patients who were either taking steroids or cromoglycate. This rise was terminated by the administration of a bronchodilator aerosol.
D001249:Asthma / Q000097:blood* / Q000503:physiopathology; D006632:Histamine / Q000494:pharmacology*; D006801:Humans; D010100:Oxygen / Q000097:blood*
D006632:Histamine; D010100:Oxygen