Diurnal variation in the inducibility of luteal 20 alpha-hydroxysteroid dehydrogenase in pregnant rats.
Luteolysis was induced in rats during late pregnancy by fetoplacental removal, and was monitored by the increased activity of luteal 20 alpha-hydroxysteroid dehydrogenase (20 alpha-OHSDH). The extent of enzyme induction over a given length of time varied according to the time of day at which the fetuses and placentae were removed, 11.00 and 21.00 h appearing to give optimal and minimal enzyme activities respectively. The 20 alpha-OHSDH was more readily induced on day 19 than on day 18.
D015089:20-Hydroxysteroid Dehydrogenases / Q000096:biosynthesis*; D000028:Abortion, Induced; D000818:Animals; D002940:Circadian Rhythm; D003338:Corpus Luteum / Q000201:enzymology*; D004790:Enzyme Induction; D005260:Female; D003341:Luteolysis; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats
D015089:20-Hydroxysteroid Dehydrogenases