Complement fixing antibody responses to virus infection in children with acute lymphoblastic leukaemia.
Thirty children with acute lymphoblastic leukaemia (ALL) were studied and had a virus isolated. Only 50% produced a significant rise in complement fixing (CF) antibody titre compared to 100% of normal children. The failure to produce antibodies was unpredictable. CF antibodies are not a reliable guide to virus infections in children with ALL.
D000208:Acute Disease; D000293:Adolescent; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000276:immunology*; D008297:Male; D014777:Virus Diseases / Q000276:immunology*
D000914:Antibodies, Viral