title: Chromosome studies in a case of monoblastic leukemia.
abstract: Chromosome analysis of a direct bone marrow preparation from a patient with acute, undifferentiated monoblastic leukemia showed a predominant clone of 51,XX,+6,+8,+4,+19,+21,11q+, along with a chromosomally normal clone. Studies with cytofluorometry confirmed the two populations of cells with different DNA content.
mesh_terms: D001853:Bone Marrow / Q000032:analysis; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005434:Flow Cytometry; D049668:History, 15th Century; D006801:Humans; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*
chemical_list: D004273:DNA, Neoplasm