Multicentric osteosarcoma.
A case of multicentric osteosarcoma is described. This is a rare variety of osteosarcoma, characterised by multiple simultaneous neoplastic bone lesions, of a radiographically sclerosing type, which precede the appearance of the pulmonary metastases. The pathological and clinical features are discussed and comparisons made with similar cases reported in the literature. The therapeutic management of this variety of osteosarcoma is outlined. The cases so far reported have always proved fatal, with a mean survival time of eight months from time of diagnosis.
D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000401:mortality* / Q000473:pathology; D011859:Radiography