Red blood cell filterability in non-diabetic patients with chronic occlusive arterial disease.
One-hundred and fifty non-diabetic patients with stage II chronic occlusive arterial disease (COAD), were tested for red blood cell filterability (RBF). At the same time, glycaemia, uricaemia, plasma cholesterol and triglycerides, fibrinogen, haematocrit, and white blood cells (granulocytes and lymphocytes) count, mean corpuscular volume, were measured. Thirty healthy people, tested for the same biological parameters, were used as controls. RBF was performed, using the Reid & Dormandy technique, with the same batch of filters (Nuclepore 5 micrometer, No. 54 A8 A25) for patients and controls. Filtration time was expressed in s.ml-1. Values obtained in patients (41.967 +/- 0.889) were significantly different (P less than 0.005) from controls (32.1 +/- 1.329). RBF alteration was correlated (P less than 0.05) with white blood cells count, haematocrit and plasma fibrinogen values. No correlation was observed with other biological parameters.
D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000097:blood* / Q000150:complications; D002908:Chronic Disease; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood*; D004910:Erythrocyte Membrane; D004912:Erythrocytes; D006801:Humans; D008851:Micropore Filters; D008875:Middle Aged; D012907:Smoking; D013997:Time Factors