title: Theoretical motivations of fluorine incorporation into the complex therapy of parodontosis.
abstract: The results of experiments on dogs with periodontal disease have proved the following: 1. Mobility of calcium in the jaws and skeleton occurs in periodontal disease. 2. The body of the mandible plays a particular role in the compensatory mineralization of the alveolar process. 3. There is a discernible increase in fluorine content in pathologically affected zones of jaw bones. 4. Small doses of fluorine are able to increase calcium deposition in jaw bones. Clinical proof has been obtained of the beneficial influence of fluorine in the complex treatment of periodontal disease, which is manifest in the retention of calcium and fluorine in the organism. The ability of fluorine to substitute for calcium in resorption of the alveolar margin and to stimulate calcium deposition in jaw bones provides theoretical support for the recommendation to incorporate small doses of fluorine into the complex therapy of periodontal disease.
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D004285:Dogs; D005461:Fluorine / Q000378:metabolism / Q000494:pharmacology*; D010510:Periodontal Diseases / Q000378:metabolism / Q000628:therapy*; D010519:Periodontium / Q000187:drug effects* / Q000378:metabolism
chemical_list: D005461:Fluorine; D002118:Calcium