Prevention of reflux after gastro resection in the pig.
In 48 pigs the duodenogastric reflux of bile acids and lysolecithin is studied after different types of gastroduodenostomy, jejunal interposition and Roux-Y-gastroenterostomy. The intragastric concentrations of bile acids and lysolecithin were found to be pathologically elevated after gastroduodenostomy. There was no difference between end-to-end, end-to-side or supraduodenal end-to-side anastomoses. An effective reflux prevention was possible by interposition of 25 cm of isoperistaltic jejunum or by Roux-Y. A shorter (15 cm) interposition with or without an isoperistaltic invagination valve was not sufficient in normalizing reflux amounts.
D000818:Animals; D001647:Bile Acids and Salts / Q000032:analysis; D001655:Bile Reflux / Q000517:prevention & control*; D001660:Biliary Tract Diseases / Q000517:prevention & control*; D005260:Female; D005769:Gastrointestinal Motility; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D010713:Phosphatidylcholines / Q000032:analysis; D011183:Postoperative Complications / Q000517:prevention & control; D013270:Stomach / Q000601:surgery*; D013552:Swine
D001647:Bile Acids and Salts; D010713:Phosphatidylcholines