Successful pregnancy during chemotherapy for acute leukemia.
A 26-year-old patient with acute lymphatic leukemic conceived while on systemic chemotherapy. This patient experienced relapse during the second trimester, and a second complete hematologic remission was achieved with doxorubicin hydrochloride, vincristine, and prednisone. A 2400-gram, but otherwise normal, male infant was delivered by Caesarean section during the 36th gestational week. Growth and development of this child is normal at six months.
D000328:Adult; D004317:Doxorubicin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007945:Leukemia, Lymphoid / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D014750:Vincristine / Q000008:administration & dosage*
D014750:Vincristine; D004317:Doxorubicin; D011241:Prednisone