Symmetric central thalamic necrosis in experimental thiamine deficient encephalopathy.
Besides the classical lesions, symmetric necrosis was found in the thalamus of pyrithiamine treated rats. The barrier systems of the two areas differ already in healthy animals and behave differently during the illness.
D000818:Animals; D001812:Blood-Brain Barrier; D002543:Cerebral Hemorrhage / Q000473:pathology; D007656:Ketoglutaric Acids / Q000097:blood; D009336:Necrosis; D011773:Pyruvates / Q000097:blood; D051381:Rats; D013788:Thalamus / Q000473:pathology*; D013832:Thiamine Deficiency / Q000473:pathology*
D007656:Ketoglutaric Acids; D011773:Pyruvates