Diffuse fasciitis with eosinophilia.
In 1974 Shulman described two patients who had a scleroderma-like thickening of the skin in association with eosinophilia. Biopsies revealed striking thickening of the fascia between the subcutaneous tissue and muscle, with intense infiltration of plasma cells and lymphocytes. There was no evidence of myositis or of the visceral manifestations of systemic sclerosis. Reports of similar patients have since appeared; we report a further patient thought to have this condition.
D000328:Adult; D004804:Eosinophils; D005205:Fascia; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000175:diagnosis; D008297:Male; D013577:Syndrome