Crystalline arrays of membrane-bound acetylcholine receptor.
Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.
D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D002474:Cell-Free System; D003461:Crystallography; D005399:Fishes; D046911:Macromolecular Substances; D008854:Microscopy, Electron; D009045:Motor Endplate / Q000648:ultrastructure; D011950:Receptors, Cholinergic / Q000276:immunology
D046911:Macromolecular Substances; D011950:Receptors, Cholinergic