title: Chronic paroxysmal hemicrania (CPH). The clinical manifestations. A review.
abstract: Eight definite and 10 possible cases of CPH are known to the authors. Decisive diagnostic features in the differential diagnosis versus ordinary cluster headache (Horton's headache) seem to be: the presence of headache every day, a high maximum daily attack frequency (greater than or equal to attacks/24 hours) and an absolute indomethacin effect. There is increasing evidence for a female preponderance in CPH. It emerges from this study that there frequently (or invariably?) is a pre-CPH stage with atypical attack pattern, usually lasting several years. Pregnancy seems to have a rather clear ameliorating effect on attack frequency and severity. In other patients, the very onset of headache is immediately after delivery. The importance of recognizing this special headache from a clinical point of view is clear since this disabling disorder can be completely abolished by drug therapy.
mesh_terms: D000367:Age Factors; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008297:Male; D008881:Migraine Disorders / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D010038:Otorhinolaryngologic Diseases / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications; D012737:Sex Factors; D013997:Time Factors
chemical_list: D007213:Indomethacin