Naturally-occurring IgA antibodies to glycerol-teichoic acid in human saliva. Correlation with caries activity.
Human subjects were examined for caries activity and for naturally-occurring salivary IgA of glycerol-teichoic acid (TA) specificity by an enzyme-linked immunosorbent assay. Subjects free of active caries produced higher levels of anti-TA in their saliva than persons with one or more active carious lesions.
D000328:Adult; D000907:Antibodies, Bacterial / Q000302:isolation & purification*; D001407:Bacillus / Q000276:immunology; D003731:Dental Caries / Q000503:physiopathology*; D004797:Enzyme-Linked Immunosorbent Assay; D005990:Glycerol / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification*; D012463:Saliva / Q000276:immunology*; D013295:Streptococcus mutans / Q000276:immunology; D013682:Teichoic Acids / Q000276:immunology*
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D013682:Teichoic Acids; D005990:Glycerol