title: Studies on osteoporosis. V. Comparison of methods of evaluation of osteoporosis and study of chromosome changes induced by neutron activation.
abstract: In vivo activation analysis was compared with ashing and atomic absorption spectrophotometry for the determination of total skeletal calcium content in mice. The results were close to identical. The possible mutagenic-carcinogenic effect of repeated exposure to whole body neutron irradiation was studied by chromosome analysis. Under the conditions of these experiments, no significant chromosome changes were seen.
mesh_terms: D000201:Activation Analysis; D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects* / Q000648:ultrastructure; D001842:Bone and Bones / Q000032:analysis*; D002118:Calcium / Q000032:analysis*; D002869:Chromosome Aberrations / Q000528:radiation effects*; D005260:Female; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D009152:Mutagenicity Tests; D009501:Neutron Activation Analysis; D009502:Neutrons; D010024:Osteoporosis / Q000175:diagnosis; D013054:Spectrophotometry, Atomic
chemical_list: D002118:Calcium