title: Penicillamine-induced skin lesions.
abstract: D-penicillamine therapy can produce an unusual variety of skin lesions: Some are acute sensitivity reactions; some are caused by metabolic effects of the drug; some are due to autoimmune phenomena or to unknown mechanisms. The type and incidence of side effects depend on the original disease and on penicillamine dosage and duration of treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases; D003094:Collagen / Q000378:metabolism; D004342:Drug Hypersensitivity; D004547:Elastic Tissue / Q000187:drug effects; D004549:Elastin / Q000378:metabolism; D005260:Female; D006801:Humans; D008010:Lichen Planus; D008297:Male; D010396:Penicillamine / Q000009:adverse effects*; D012871:Skin Diseases / Q000139:chemically induced*; D013997:Time Factors
chemical_list: D003094:Collagen; D004549:Elastin; D010396:Penicillamine