title: Some data on the proliferative activity of prolymphocytic leukemia.
abstract: Two cases of prolymphocytic leukemia were studied in order to find out whether or not there is a correlation between the fatal prognosis and the cell proliferation activity. Mitotic indices, DNA-contents, and nuclear and nucleolar sizes were essentially higher than in chronic lymphatic leukemia corresponding to values of immunoblastic sarcoma. The different proliferation activities of the two cases reflected their divergent courses of 9 and more than 24 months, respectively.
mesh_terms: D000368:Aged; D002466:Cell Nucleolus; D002467:Cell Nucleus; D004247:DNA / Q000096:biosynthesis; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood*; D008214:Lymphocytes; D008223:Lymphoma / Q000097:blood; D008875:Middle Aged; D008938:Mitosis; D011379:Prognosis
chemical_list: D004247:DNA