title: Confirmation and further regional assignment of aminoacylase 1 (acy-1) on human chromosome 3 using a simplified detection method.
abstract: An improve method for the detection of aminoacylase-1 (ACY-1) is described. Data from human-rodent interspecific hybrids confirm the assignment of ACY-1 to human chromosome 3. The most likely site for ACY-1 appears to be 3p21 to 3pter. The enzyme ACY-1 hydrolyses both acetyl methionine and acetyl glutamate.
mesh_terms: D000581:Amidohydrolases / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D006224:Cricetinae; D003412:Cricetulus; D004592:Electrophoresis, Starch Gel; D005819:Genetic Markers; D005971:Glutamates; D006801:Humans; D006822:Hybrid Cells; D008715:Methionine / Q000031:analogs & derivatives; D008722:Methods; D051379:Mice
chemical_list: D005819:Genetic Markers; D005971:Glutamates; C006379:N-acetylmethionine; D008715:Methionine; D000581:Amidohydrolases; C019672:aminoacylase I; C016195:N-acetylglutamic acid