The source of plasminogen activator in human saliva.
Human mixed stimulated saliva (MSS) has fibrinolytic activity (plasminogen activator activity) but no such activity could be demonstrated in the supernatants of mixed stimulated, parotid or submandibular salivas. Resuspended pellets from MSS showed a fibrinolytic activity only in association with epithelial cells and cell fragments. It is concluded that the fibrinolytic activity of MSS is related to its epithelial cell component.
D000293:Adolescent; D000328:Adult; D004847:Epithelial Cells; D004848:Epithelium / Q000201:enzymology; D005342:Fibrinolysis; D006801:Humans; D010960:Plasminogen Activators / Q000378:metabolism*; D012463:Saliva / Q000201:enzymology*
D010960:Plasminogen Activators