Isolated parotid acinar cells from DL-isoproterenol-treated rats. A cellular model for cystic fibrosis.
The morphology and composition of isolated acinar cells from the enlarged parotid glands of rats treated chronically with DL-isoproterenol were investigated and compared with isolated acinar cells from parotids of control untreated rats. Changes similar to those observed in parotid acinar cells from patients with cystic fibrosis were demonstrated.
D000818:Animals; D002469:Cell Separation; D002470:Cell Survival; D003550:Cystic Fibrosis / Q000473:pathology*; D006984:Hypertrophy / Q000473:pathology; D007545:Isoproterenol / Q000009:adverse effects*; D008297:Male; D008954:Models, Biological; D009940:Organoids / Q000648:ultrastructure; D010306:Parotid Gland / Q000032:analysis / Q000166:cytology* / Q000187:drug effects; D051381:Rats
D007545:Isoproterenol