The valve of prednisone in the prevention of scarring after vasovasostomy.
A trial, comparing 20 patients undergoing reanastomosis of their vasa following bilateral vasectomy, with 20 patients undergoing the same procedure but in whom prednisone, 40 mg daily for six weeks, had been given to prevent postoperative fibrosis at the anastomotic site, has been conducted. The results suggest that there is a slight increase in the number of successful pregnancies (45% to 55%), and a significant increase in the number of patients in whom sperms have reappeared within the semen (70% to 95%) in the group in whom prednisone has been used.
D000328:Adult; D002921:Cicatrix / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D013076:Sperm Count; D014649:Vas Deferens / Q000601:surgery*; D014659:Vasectomy / Q000534:rehabilitation
D011241:Prednisone