Local effects of PGF2 alpha and embryonic extracts on luteal function in swine.
Individual corpora lutea (CL) from 10 gilts were assigned to seven treatment groups. Corpora lutea assigned to group 1 were unimplanted, while those in groups 2 through 7 were given implants congealed with saline, prostaglandin F2 alpha (PGF2 alpha) vehicle, PGF2 alpha, PGF2 alpha and untreated embryonic extracts, PGF2 alpha and heated embryonic extracts or PGF2 alpha and charcoal-adsorbed embryonic extracts, respectively. Individual CL implanted with PGF2 alpha alone had a lower (P less than .05) mean weight and progesterone concentration than CL in all other treatment groups except those treated with PGF2 alpha and charcoal-adsorbed embryonic extracts. Untreated and heat-treated embryonic extracts prevented the reduction in luteal weight and progesterone concentration induced by PGF2 alpha treatment.
D000818:Animals; D002606:Charcoal; D003338:Corpus Luteum / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D015237:Dinoprost; D004343:Drug Implants; D004622:Embryo, Mammalian; D005260:Female; D006358:Hot Temperature; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011374:Progesterone / Q000378:metabolism; D011460:Prostaglandins F / Q000008:administration & dosage / Q000494:pharmacology*; D013552:Swine / Q000502:physiology*; D014020:Tissue Extracts / Q000008:administration & dosage / Q000494:pharmacology*
D004343:Drug Implants; D011460:Prostaglandins F; D014020:Tissue Extracts; D002606:Charcoal; D011374:Progesterone; D015237:Dinoprost