A study on the stability of prostaglandin E2 in methylhydroxyethylcellulose gel by gas chromatography.
A method is reported for the analysis of prostaglandin PGE2 in methylhydroxyethylcellulose gel. Stability studies using the method have shown that the degradation of PGE in the gel is a first order process at 4 degrees and 25 degrees C. Five per cent breakdown had taken place after 7 days storage in the refrigerator and after 32 h at room temperature.
D002849:Chromatography, Gas; D015232:Dinoprostone; D004355:Drug Stability; D005782:Gels; D008747:Methylcellulose / Q000031:analogs & derivatives*; D011458:Prostaglandins E / Q000032:analysis*
D005782:Gels; D011458:Prostaglandins E; D008747:Methylcellulose; C034430:methyl hydroxyethyl cellulose; D015232:Dinoprostone