title: Estramustine phosphate therapy in poorly differentiated carcinoma of the prostate.
abstract: Ninety patients with poorly differentiated prostatic carcinoma have been treated with Estramustine phosphate (Estracyt). Seventeen of them had clinically metastases and had had no previous therapy. Seventy-three were initially given oestrogens and/or irradiation. Objective response was observed in 59%. The best effect was seen in patients primarily untreated.
mesh_terms: D000135:Acid Phosphatase / Q000097:blood; D001859:Bone Neoplasms / Q000556:secondary; D004961:Estramustine / Q000627:therapeutic use*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D009588:Nitrogen Mustard Compounds / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000201:enzymology
chemical_list: D009588:Nitrogen Mustard Compounds; D004961:Estramustine; D000135:Acid Phosphatase