title: Sensitivity of serum glutamic oxaloacetic transaminase and bile acid levels for the detection of experimental liver injury in rats.
abstract: Serum glutamic oxaloacetic transaminase (SGOT) and serum bile acid levels (SBA) were determined in serial blood samples of rats treated with two different hepatotoxins (carbon tetrachloride or D-galactosamine). SGOT was found to be more sensitive than SBA in detecting experimental liver injury.
mesh_terms: D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D001647:Bile Acids and Salts / Q000097:blood*; D002251:Carbon Tetrachloride / Q000633:toxicity; D056486:Chemical and Drug Induced Liver Injury; D004796:Clinical Enzyme Tests; D004195:Disease Models, Animal; D005688:Galactosamine / Q000633:toxicity; D008107:Liver Diseases / Q000175:diagnosis*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001647:Bile Acids and Salts; D005688:Galactosamine; D002251:Carbon Tetrachloride; D001219:Aspartate Aminotransferases