title: Treatment of uncomplicated genital Chlamydia trachomatis infections in males.
abstract: The treatment of chlamydial urethritis in males depends on the susceptibility of Chlamydia trachomatis to different antimicrobial agents. Tetracyclines seem to be the drugs of choice; long-acting tetracyclines are recommended, as these are more convenient for the patient. Both lymecycline and doxycycline produce clinical and bacteriological cure in approximately 90% of cases, when used in adequate doses. Erythromycin is the alternative treatment in patients who should not be given tetracyclines. Trimethoprim/sulfamethoxazole is effective in patients with chlamydial urethritis, but it seems to be ineffective in those with Chlamydia-negative urethritis. The importance of treating sexual partners should not be overlooked.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000188:drug therapy*; D002692:Chlamydia trachomatis; D004318:Doxycycline / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D005832:Genital Diseases, Male / Q000188:drug therapy*; D006801:Humans; D008194:Lymecycline / Q000627:therapeutic use; D008297:Male; D013754:Tetracyclines / Q000627:therapeutic use; D014526:Urethritis / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D013754:Tetracyclines; D004917:Erythromycin; D008194:Lymecycline; D004318:Doxycycline