Scanning electron microscopic study of three human breast cancer cell lines.
The surface features of three human breast cancer cell lines (MDA-MB-134, MDA-MB-175 and MDA-MB-231) and of one nontumorigenic line derived from breast milk (HBL-100) were studied by scanning electron microscopy. Cells of eight to ten different passages were investigated. The MDA-MB lines were pleomorphic, with the presence of microvilli a constant feature; blebs were occasionally observed. These features were absent in the HBL-100 cells, which had an almost smooth surface.
D001943:Breast Neoplasms / Q000648:ultrastructure*; D002460:Cell Line; D002462:Cell Membrane / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure