Neurotoxic effects of root filling materials on rat phrenic nerve in vitro.
Inhibitory effects of root filling materials on the conduction of action potentials evoked in rat phrenic nerves were evaluated in vitro. Endomethasone and N2 Normal completely and irreversibly inhibited conductance; ProcoSol caused complete but reversible inhibition; Kloroperka N-O caused total inhibition which was sometimes reversed; and AH26 and Diaket showed partial inhibition which was partially reversible.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D010791:Phrenic Nerve / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D013997:Time Factors
D012387:Root Canal Filling Materials