Transfer, tissue localization and proliferation of fetal cells in pregnant mice.
Matings between Rb7-Rb7 male mice, possessing the Rb7 chromosomal marker, with CBA, C57/B1, Swiss or F1 BALB/SJL females were carried out to determine whether fetal cells transferred into maternal tissues. Rb7 cells undergoing spontaneous mitosis were sought in maternal blood, bone marrow, thymus, para-aortic lymph nodes, Peyer's patches and liver. Proliferation fetal cells were unequivocally demonstrated in maternal spleen and bone marrow, 12-21 days after mating.
D000818:Animals; D001773:Blood Cells; D001854:Bone Marrow Cells; D002871:Chromosome Banding; D005260:Female; D005333:Fetus / Q000166:cytology*; D005819:Genetic Markers; D008099:Liver / Q000166:cytology; D008198:Lymph Nodes / Q000166:cytology; D008297:Male; D008431:Maternal-Fetal Exchange; D051379:Mice; D008815:Mice, Inbred Strains; D011247:Pregnancy; D013154:Spleen / Q000166:cytology; D013950:Thymus Gland / Q000166:cytology
D005819:Genetic Markers