Immunological approach to the treatment of acute lymphoblastic leukemia.
On the basis of experimental results an immunological method of acute lymphoblastic leukemia treatment by means of specific immunity regulation was designed. The administration of antibodies (immunoglobulins) with prednisolone to patients induced 100% remissions in a comparatively short time. None of the patients treated with immunoprednisolone therapy had neuroleukemia. The immunological findings indicate that the therapeutic effect depends on the "deblocking" action of the applied immune preparation.
D000208:Acute Disease; D000293:Adolescent; D000912:Antibodies, Neoplasm / Q000008:administration & dosage*; D001932:Brain Neoplasms / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage; D007075:Immunoglobulin M / Q000008:administration & dosage; D007167:Immunotherapy; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000628:therapy*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage
D000912:Antibodies, Neoplasm; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011241:Prednisone