Critical appraisal of the experimental studies on the ototoxic interaction between ethacrynic acid and aminoglycoside antibiotics. A pharmacokinetical standpoint.
D000617:Aminoglycosides / Q000009:adverse effects / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000378:metabolism; D003051:Cochlea / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D003055:Cochlear Microphonic Potentials / Q000187:drug effects; D004347:Drug Interactions; D004710:Endolymph / Q000378:metabolism; D004976:Ethacrynic Acid / Q000009:adverse effects* / Q000378:metabolism; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D008297:Male; D010498:Perilymph / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D004976:Ethacrynic Acid