title: Anaphylactic reaction to methotrexate used in high doses as an adjuvant treatment of osteogenic sarcoma.
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000276:immunology; D012516:Osteosarcoma / Q000188:drug therapy*
chemical_list: D008727:Methotrexate