A domain of clathrin that forms coats.
Triskelions, trimeric complexes of clathrin and associated light chains, are the assembly units of clathrin coats [Ungewickell, E. & Branton, D. (1981) Nature (London) 289, 420-422; Kirchhausen, T. & Harrison, S. C. (1981) Cell 23, 755-761]. We report here that triskelions whose outer arms have been removed by trypsin digestion retain the ability to be assembled into coats. These digested timers contain a 110,000 molecular weight domain of clathrin and lack intact light chains.
D000818:Animals; D001921:Brain / Q000378:metabolism; D002417:Cattle; D002966:Clathrin; D008565:Membrane Proteins / Q000302:isolation & purification* / Q000378:metabolism; D008854:Microscopy, Electron; D008970:Molecular Weight; D010446:Peptide Fragments / Q000032:analysis; D014357:Trypsin
D002966:Clathrin; D008565:Membrane Proteins; D010446:Peptide Fragments; D014357:Trypsin