Humoral antibodies to anaerobic bacteria isolated from patients with pulpal-periapical disease.
The purpose of this investigation was to determine if anaerobic bacteria isolated from pulpal-periapical infections elicit a humoral immune response in the host. Results indicated that patients with pulp and periapical disease do not have significantly raised levels of IgG or IgM in their serum and that in the acute sera the precipitin antibody titer to the anaerobic bacteria was significantly higher in the patient group than in the control group. However, there was no significant difference in antibody titer for the convalescent sera in the patient and control groups or the acute and convalescent sera for the patient group.
D000693:Anaerobiosis; D000907:Antibodies, Bacterial / Q000032:analysis*; D001419:Bacteria / Q000276:immunology; D003788:Dental Pulp Diseases / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D010483:Periapical Diseases / Q000276:immunology*
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007075:Immunoglobulin M