Major bone lesions in acute lymphoblastic leukaemia.
The records of 1471 patients with ALL entered into UKALL trials II-V (1972-1977) were studied, and major bone lesions at diagnosis were recorded in 47 (3.2%). These were found predominantly in young patients (median age 5 years), equally in both sexes, and were seen to be associated with a low blood leucocyte count and prolonged remissions.
D000293:Adolescent; D001859:Bone Neoplasms / Q000453:epidemiology / Q000556:secondary*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000473:pathology*; D007958:Leukocyte Count; D008297:Male; D011379:Prognosis; D012737:Sex Factors; D013997:Time Factors; D006113:United Kingdom