title: Of rabbit and man: comparative gene mapping.
abstract: Nineteen cell hybrids were obtained by fusing rabbit (Oryctolagus, OCU) fibroblasts and a Chinese hamster cell line HGPRT. Eleven enzymatic markers were investigated for cosegregation analysis. Seven could be assigned to OCU chromosomes: LDHA to OCU1; LDHB and TPI to OCU4; PEPB, NP, and ITP to OCU16; and G6PD to OCUX. Two assignments were considered possible: MDH2 to OCU15, and GUK to OCU3 or 15. Two could not be assigned: MDHI and PGD. These results are consistent with the OCU-HSA chromosome homoeologies previously reported, except for PEPB.
mesh_terms: D000818:Animals; D002459:Cell Fusion; D002874:Chromosome Mapping; D006224:Cricetinae; D004798:Enzymes / Q000235:genetics*; D005796:Genes; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D011817:Rabbits / Q000235:genetics*
chemical_list: D004798:Enzymes; D005819:Genetic Markers