[Prognostic importance of DNA histograms of bone marrow cells in acute myeloblastic leukemias].
DNA histograms were studied in bone marrow cells in 25 patients with acute myeloblastic leukaemia before starting treatment. It was found that patients with complete remission showed a significantly higher proportion of cells in phase S of the cellular cycle (22 +/- 3%) than patients who failed to achieve remission (12 +/- 4%). Assessment of DNA citrograms of bone marrow cells may be one of prognostic factors in acute myeloblastic leukaemia.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007399:Interphase; D015470:Leukemia, Myeloid, Acute / Q000032:analysis / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010783:Photometry; D011379:Prognosis
D004273:DNA, Neoplasm
Znaczenie prognostyczne histogramów DNA komórek szpiku w ostrych białaczkach mieloblastycznych.