Surface glycoproteins of human sarcoma- and fibroblastic cells.
A comparison was made of the cell surface glycoproteins of four human cell lines, namely a giant tumor of bone cell line, an osteosarcoma line, a fibrosarcoma line and a human fibroblast line. The cells were labeled by lactoperoxidase catalyzed iodination and the glycoproteins extracted by 0.5% Triton X-100 were bound to lentil-lectin and subsequently analyzed by SDS gel electrophoresis. While the cell lines examined shared a series of common glycoproteins, it was found that the giant cell tumor line and the fibrosarcoma lines exhibited a higher degree of homology than the other cell lines.
D002460:Cell Line; D004591:Electrophoresis, Polyacrylamide Gel; D005347:Fibroblasts / Q000032:analysis; D005354:Fibrosarcoma / Q000032:analysis; D005870:Giant Cell Tumors / Q000032:analysis; D006023:Glycoproteins / Q000032:analysis*; D006801:Humans; D012516:Osteosarcoma / Q000032:analysis; D012509:Sarcoma / Q000032:analysis*
D006023:Glycoproteins