title: Variations in amnesia with intravenous diazepam.
abstract: Volunteer senior students who had not previously received a benzodiazepine were employed to determine whether amnesia induced by the intravenous administration of diazepam remained constant. Profoundness of amnesia was tested 24 hours after drug administration following a first and second exposure to the drug. The two experiences were set 28 days apart. The study showed that recall of events in the immediate post-drug administration period was likely to be less impaired following a second exposure to diazepam than following the first. It also revealed that recall of visual stimuli was significantly better than recall of cutaneous-tactile stimuli. The clinical implications of these findings are discussed.
mesh_terms: D000647:Amnesia / Q000139:chemically induced*; D000771:Anesthesia, Intravenous; D003975:Diazepam / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D007275:Injections, Intravenous; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects; D013997:Time Factors
chemical_list: D003975:Diazepam