[Quantitative shifting of intra and peritumoral cell populations after intratumoral BCG-cell-wall therapy in squamous epithelial mouth neoplasms].
A qualitative histologic examination of squamous cell carcinoma of the buccal cavity was made before and after the injection of BCG cell walls directly into the tumor. The density of the inflammatory infiltrate in and at the tumor site differed significantly. The distribution pattern of the cells involved in the infiltrate showed an increased number of lymphocytes and histiocytes. Lymphocytes, the largest cell group represented, were more frequently demonstrated in the tumor than outside it. The injection of BCG cell walls directly into the tumor primarily causes a shift in the total number of cells and only secondarily an alteration in the distribution pattern of the cells involved in the infiltrate.
D000287:Administration, Topical; D001500:BCG Vaccine / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy*; D006644:Histiocytes; D006801:Humans; D008214:Lymphocytes; D009062:Mouth Neoplasms / Q000601:surgery / Q000628:therapy*
D001500:BCG Vaccine
Quantitative Verschiebung intra- und peritumoraler Zellpopulationen nach intratumoraler BCG-Zellwand-therapie bei Plattenepithelkarzinomen der Mundhöhle.