Acute pulpal-alveolar cellulitis syndrome. II. Clinical assessment of antibiotic effectiveness against microbes isolates from intact teeth.
Ten antibiotics were comprehensively screened for effectiveness against 105 microbes, specifically isolated from seventy-eight teeth involved with acute pulpal-alveolar cellulitis. On the basis of effectiveness and compatibility, erythromycin was regarded as the drug of choice for initial therapy. Streptococci were the predominant class of microbes isolated; enterococci were the most resistant. No resistance was noted wit erythromycin; 52 percent resistance was obtained with clindamycin. Tetracycline was the most effective of the common drugs for aerobic gram-negative rods. Polyantibiotic resistance was noted among microbes of all types. A clinical perspective in drug therapy for acute oral infection is discussed.
D000208:Acute Disease; D000539:Alveolar Process / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002481:Cellulitis / Q000382:microbiology*; D003788:Dental Pulp Diseases / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D006801:Humans; D007571:Jaw Diseases / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D013577:Syndrome
D000900:Anti-Bacterial Agents