In vitro metabolism of 4-pregnenes in ovaries of a freshwater teleost, the ayu (Plecoglossus altivelis): production of 17 alpha, 20 beta-dihydroxy-4-pregnen-3-one and its 5 beta-reduced metabolites, and activation of 3 beta- and 20 beta-hydroxysteroid dehydrogenases by treatment with a fish gonadotropin.
D015089:20-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D005399:Fishes / Q000378:metabolism*; D006062:Gonadotropins / Q000494:pharmacology*; D006908:Hydroxyprogesterones / Q000096:biosynthesis* / Q000378:metabolism; D010053:Ovary / Q000187:drug effects / Q000378:metabolism*; D011279:Pregnanetriol / Q000378:metabolism; D011280:Pregnanolone / Q000031:analogs & derivatives / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism
D006062:Gonadotropins; D006908:Hydroxyprogesterones; C016844:salmon gonadotropin; C021012:17 alpha,20 beta-dihydroxypregn-4-en-3-one; D011279:Pregnanetriol; C013051:17-hydroxypregnanolone; D011374:Progesterone; D011280:Pregnanolone; D015096:3-Hydroxysteroid Dehydrogenases; D015089:20-Hydroxysteroid Dehydrogenases