title: [Karyotype in chronic myeloid leukemia in a blastic crisis. I. Monosomy 16].
abstract: One case of Chronic Granulocytic Leukemia is reported, in which the patient showed, during a blastic crisis, an aneupolid cariotype 45, XX, t (9; 22) (q34; q11), -16. This paper emphasizes the rare involvement of the chromosome 16 in Leukemias, and stresses the high frequency of the alterations of the chromosome group E in the course of blastic crisis.
mesh_terms: D002869:Chromosome Aberrations; D002902:Chromosomes, Human, 16-18; D005260:Female; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics
vernacular_title: Cariotipo nella leucemia mieloide cronica in crisi blastica. I) Monosomia 16.