Prostatic carcinoma: comments on radical surgical treatment.
Total prostatectomy and potentially non-curative forms of treatment for prostatic carcinoma have produced identical survival times in the past. The most likely reason for this is the presence of large numbers of less aggressive tumors in these series. Retrospective study leads to the identification of high and low risk groups of tumors by the combined consideration of local extension and grade of differentiation. It is suggested that low risk groups should be excluded from radical treatment. The effectivity of total prostatectomy is indicated by the results of treatment obtained in the high risk groups. Definitive answers as to the value of radical surgery should be obtainable by applying the treatment concepts outlined in this report to controlled studies.
D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000601:surgery*; D012306:Risk