The influence of drugs on the acute toxicity of cytisine.
The effect of various drugs on the acute toxicity of cytisine, the toxic constituent of Laburnum anagyroides Med, was studied in mice. Drugs were tested which have been recommended for symptomatic treatment of laburnum poisoning. Drugs which influence the CNS reduce the acute toxicity of cytisine more effectively than those with predominantly peripheral site of action.
D000470:Alkaloids / Q000633:toxicity*; D000818:Animals; D001392:Azocines / Q000633:toxicity*; D004347:Drug Interactions; D007928:Lethal Dose 50; D051379:Mice; D011807:Quinolizines; D000093843:Quinolizidine Alkaloids
D000470:Alkaloids; D001392:Azocines; D011807:Quinolizines; C004712:cytisine; D000093843:Quinolizidine Alkaloids