Ultrastructure of a hyaluronic acid matrix.
Freeze-etch replicas of a hylauronic acid matrix were visualized by electron microscopy. In water a coarse branching fibrillar network of hyaluronic acid aggregates was seen. The high solvent permeability of this matrix suggests that the spaces observed are relatively devoid of unaggregated polymer. Addition of calcium disordered the matrix, resulting in a more dispersed felt of polymer.
D005110:Extracellular Space; D005613:Freeze Etching; D006801:Humans; D006820:Hyaluronic Acid; D008854:Microscopy, Electron
D006820:Hyaluronic Acid