Comparison of nuclear proteins of differentiation-induced and uninduced Friend erythroleukemia cells.
Nuclear non-histone protein content decreased to about 50% during the course of differentiation of Friend cells (Morioka, K., Tanaka K, & Ono, T. (1980) J. Biochem. 88 517-524). Judging from the patterns of Coomassie blue staining after SDS-polyacrylamide gel electrophoresis, the contents of non-histone proteins generally decreased, except for a few proteins such as IP25, while no marked change was observed in histones during differentiation.
D000081:Acetamides / Q000494:pharmacology; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002467:Cell Nucleus / Q000378:metabolism*; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D003959:Diamines / Q000494:pharmacology; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D005622:Friend murine leukemia virus; D006657:Histones / Q000378:metabolism; D004915:Leukemia, Erythroblastic, Acute / Q000378:metabolism*; D007942:Leukemia, Experimental / Q000378:metabolism*
D000081:Acetamides; D002868:Chromosomal Proteins, Non-Histone; D003959:Diamines; D006657:Histones; C014026:hexamethylene bisacetamide; D004121:Dimethyl Sulfoxide