title: Relationship of total ascorbic acid to prostaglandins F2 alpha and E2 levels in the blood of women during the 3rd trimester of normal pregnancy.
abstract: Concentrations of Prostaglandins E2 and F2 alpha in the peripheral venous blood of women during the third trimester of normal pregnancy have been estimated using radioimmunoassay techniques. These values have been related to the levels of total ascorbic acid in the blood. It appears that AA acts to control the ratio between PGE2 and PGF2 alphja in the body. This effect may in turn be mediated via its actions on histamine levels. We have already suggested that AA acts as a modulator to control the synthesis, release and/or breakdown of histamine in the body.
mesh_terms: D001205:Ascorbic Acid / Q000097:blood*; D015237:Dinoprost; D015232:Dinoprostone; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011458:Prostaglandins E / Q000097:blood*; D011460:Prostaglandins F / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods; D012016:Reference Values
chemical_list: D011458:Prostaglandins E; D011460:Prostaglandins F; D015237:Dinoprost; D015232:Dinoprostone; D001205:Ascorbic Acid