Growth and regression of human tumor cell lines in congenitally athymic (rnu/rnu) rats.
Athymic rats were inoculated with cells from nine human tumor tissue culture cell lines. Tumor growth was seen with seven of the cell lines; histologically, the tumors resembled the tumors from which the cell lines were originated. Only one cell line--a malignant melanoma--grew progressively. The remaining sex cell lines grew to a short period of time and then regressed.
D000818:Animals; D002460:Cell Line; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008545:Melanoma; D009365:Neoplasm Regression, Spontaneous; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000276:immunology / Q000502:physiology; D013997:Time Factors; D014183:Transplantation, Heterologous; D014846:Vulvar Neoplasms / Q000473:pathology