title: Candidal splenic abscesses complicating acute leukemia of childhood treated by splenectomy.
abstract: Two patients with acute leukemia were found to have candidal splenic abscesses. Both patients were in remission and had normal granulocyte counts at the time the abscesses became evident. Both patients were treated with splenectomy and antifungal therapy with a definite response. The incidence and treatment of fungal splenic abscesses in leukemia patients is discussed with emphasis on the role of splenectomy.
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000601:surgery*; D000208:Acute Disease; D000666:Amphotericin B / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000150:complications / Q000188:drug therapy*; D007945:Leukemia, Lymphoid / Q000150:complications / Q000188:drug therapy*; D008297:Male; D013156:Splenectomy; D013158:Splenic Diseases / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000666:Amphotericin B