Vincristine-induced laryngeal nerve paralysis.
The neurotoxicity of the Vinca alkaloids vincristine and vinblastine is well recognized. Less recognized is laryngeal nerve paralysis induced by these chemotherapeutic agents. This potentially dangerous paralysis is usually reversible when the drug is withdrawn, but other causes of hoarseness in a cancer patient must be considered. I add two cases to 19 previously documented.
D000208:Acute Disease; D000328:Adult; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D008297:Male; D014750:Vincristine / Q000009:adverse effects*; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
D014750:Vincristine