Acute myeloblastic leukemia following chemotherapy for mycosis fungoides.
The development of acute myeloblastic leukemia following therapy for malignant disorders is being recognized with increasing frequency. Acute myeloblastic leukemia (erythroleukemic variant) developed in a patient with mycosis fungoides following three years of chemotherapy with a variety of antineoplastic drugs. The patient demonstrated a hypodiploid chromosomal abnormality with a missing C group chromosome.
D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002452:Cell Count; D002872:Chromosome Deletion; D002906:Chromosomes, Human, 6-12 and X; D004359:Drug Therapy, Combination; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000188:drug therapy; D012878:Skin Neoplasms / Q000188:drug therapy
D000970:Antineoplastic Agents