title: Chemical plaque control and extrinsic discoloration of teeth.
abstract: Extrinsic discoloration of teeth is an unwanted side-effect in connection with the use of the chemical plaque-preventive agent chlorhexidine. Individual differences in discoloration tendency have, however, been observed. In order to study the nature of these extrinsic discolorations a selection of 3 typical "stainers" and 3 "non-stainers" was made based on the individual tendency to develop extrinsic discolorations of teeth after a ten days rinsing with 0.2% chlorhexidine twice a day. The individual discoloration tendency was maintained through various plaque-preventive regimens. Interference with the retention of chlorhexidine by a cation demonstrated a close correlation between antiplaque activity and the discoloration tendency. A commercial oxidizing agent based on peroxy monosulfate showed the most promising properties in reducing this extrinsic discoloration without interfering with plaque-prevention.
mesh_terms: D001419:Bacteria / Q000187:drug effects; D002710:Chlorhexidine / Q000009:adverse effects* / Q000494:pharmacology; D003773:Dental Plaque / Q000517:prevention & control*; D006801:Humans; D014075:Tooth Discoloration / Q000139:chemically induced*
chemical_list: D002710:Chlorhexidine