Inducible DNA repair in Ustilago maydis.
Maximum survival of UV-irradiated U. maydis required a 2-3 h period of post-irradiation RNA and protein synthesis. Split dose experiments showed that this requirement correlated with the development of a radio-resistant cell state induced by UV doses above 200 Jm-2. Once induced, the radio-resistant state precluded the need for further RNA and protein synthesis for proficient repair of DNA damage caused by a second UV dose. Such radio-resistance was retained for up to 15 hours and it is concluded that this phenomenon represents the expression of an inducible DNA repair process, which is under transcriptional control.
D001487:Basidiomycota / Q000235:genetics*; D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D004790:Enzyme Induction; D005656:Fungal Proteins / Q000096:biosynthesis; D012331:RNA, Fungal / Q000096:biosynthesis; D014466:Ultraviolet Rays; D014588:Ustilago / Q000235:genetics* / Q000528:radiation effects
D005656:Fungal Proteins; D012331:RNA, Fungal