Effects of strontium administration on rat molar morphology.
Strontium at concentrations of 0, 50 and 150 mg/l was given to rats during pregnancy and to the pups during a pre- and post-weaning period. Measurements were made on first and second mandibular molars to assess the morphology of tooth and fissure dimensions, and enamel and dentine thickness. A significant increase in horizontal and vertical dentine thickness was associated with a level of 50 mg Sr/l, a concentration previously found to be associated with decreased caries prevalence in rats.
D000818:Animals; D003743:Dental Enamel / Q000033:anatomy & histology; D003804:Dentin / Q000033:anatomy & histology; D005260:Female; D008297:Male; D008334:Mandible; D008963:Molar / Q000033:anatomy & histology / Q000187:drug effects* / Q000196:embryology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013324:Strontium / Q000494:pharmacology*
D013324:Strontium