HLA-DR4 antigen and IgA nephropathy.
HLA-A, B and DR antigens were tested in 45 unrelated patients with IgA nephropathy (Berger's disease). A significant association with HLA-DR4 was noted. An unusual finding was a secondary association with the A2-B12 antigen combination.
D000949:Histocompatibility Antigens Class II; D006801:Humans; D007070:Immunoglobulin A; D007674:Kidney Diseases / Q000235:genetics / Q000276:immunology*; D007678:Kidney Glomerulus / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology
D000949:Histocompatibility Antigens Class II; D007070:Immunoglobulin A