Role of a 16S glycoprotein complex in cellular adhesion.
Myogenic cells release into their culture medium a glycoprotein complex that mediates cellular adhesion. In the absence of calcium this complex has a sedimentation value of 16S; it aggregates in the presence of calcium. The 16S material both agglutinates and increases the rate of cell-substratum adhesion of a myoblast variant and inhibits the adhesion of a nerve-like cell line to culture dishes. It is also a hemagglutinin. The 16S particle is composed of glycosaminoglycans and several proteins, including fibronectin and collagen.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002448:Cell Adhesion; D002449:Cell Aggregation; D002478:Cells, Cultured; D005110:Extracellular Space / Q000502:physiology; D006023:Glycoproteins / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism; D006388:Hemagglutinins; D007739:L Cells; D051379:Mice; D008970:Molecular Weight
D006023:Glycoproteins; D006025:Glycosaminoglycans; D006388:Hemagglutinins; D002118:Calcium