Cardiotoxicity of drugs detected on chicken embryos.
Results of direct observation of the effects of 9 drugs with known cardiotoxic properties upon the embryonic chick heart after intraamniotic administration on days 4 and 3 respectively, revealed the possibility of rough detection of cardiotoxic properties of newly developed drugs using the rapid, simple and inexpensive technique on chicken embryos.
D000818:Animals; D002642:Chick Embryo; D006331:Heart Diseases / Q000139:chemically induced*; D007928:Lethal Dose 50; D014116:Toxicology