Red cell filterability and chronic renal failure.
Filterability has been studied during chronic renal failure (with creatinin level above 350 mumol/l); red cells were washed thrice with 9 g/l NaCl or 40 g/l human serum albumin), adjusted to give a PCV of 0.3 and filtered on polycarbonate sieves with pore sizes of 5 micrometer. In the uremic patients groups, the results are heterogeneous and show a significant reduction of the red cell filterability. The filtration time is not well correlated with the degree of uraemia but with the haemoglobin level.
D004910:Erythrocyte Membrane; D004912:Erythrocytes; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D008833:Microcirculation; D008851:Micropore Filters; D012709:Serum Albumin / Q000494:pharmacology; D012965:Sodium Chloride / Q000494:pharmacology; D013154:Spleen / Q000503:physiopathology
D012709:Serum Albumin; D012965:Sodium Chloride