Case report: hepatic vein thrombosis (acute Budd-Chiari syndrome) in acute leukemia.
A 29-year-old female with acute promyelocytic leukemia presented with severe liver dysfunction and disseminated intravascular coagulation. Her condition rapidly deteriorated and she expired before any antileukemic therapy could be administered. At autopsy, she was found to have massive thrombosis of hepatic veins and their tributaries. Microscopic picture of liver was consistent with acute Budd-Chiari Syndrome, presumably due to the coexisting acute promyelocytic leukemia.
D000328:Adult; D006502:Budd-Chiari Syndrome / Q000209:etiology*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*