Rejection of stable cultured allografts by active or passive (adoptive) immunization.
Injection of live lymphoid cells of donor strain or immune cells of recipient strain resulted in rejection of previously stable cultured mouse thyroid allografts. The results are interpreted to indicate that a cultured graft is relatively ineffective in activating recipient lymphocytes but is capable of maintaining them in an activated state and serving as a target for them once they are activated.
D000818:Animals; D002478:Cells, Cultured; D006084:Graft Rejection; D007114:Immunization; D007116:Immunization, Passive; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D051379:Mice; D013154:Spleen / Q000276:immunology; D013997:Time Factors