title: In vitro radiosensitivity of human leukemia cell lines.
abstract: The in vitro radiobiologic survival values (n, D0) of four tumor lines derived from human hematopoietic tumors were studied. These cell lines were HL50 (n = 1.3, D0 = 117 rad[1.17 Gy]), promyelocytic leukemia; K562 (n = 1.4, D0 = 165 rad[1.65 Gy]), erythroleukemia; 45 (n = 1.1, D0 = 147 rad[1.47 Gy]), acute lymphocyte leukemia; and 176 (n = 4.0, D0 = 76 rad[0.76 Gy]), acute monomyelogenous leukemia. More cell lines must be examined before the exact relationship between in vitro radiosensitivity and clinical radiocurability is firmly established.
mesh_terms: D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D066298:In Vitro Techniques; D007938:Leukemia / Q000473:pathology*; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology; D007945:Leukemia, Lymphoid / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D011836:Radiation Tolerance