title: Extrahepatic biliary carcinomas in Asiatic bears.
abstract: Extrahepatic biliary carcinomas occurred in 2 Asiatic bears at the National Zoological Park in Washington, D.C. The tumors were associated with ascites in both cases and jaundice in 1 and metastasized widely. Neither bear had gallstones. Microscopically, the tumors were infiltrative, scirrhous adenocarcinomas that produced varying amounts of mucin. A genetic predisposition and change from the natural diet were factors proposed to contribute to the development of this neoplasm.
mesh_terms: D000818:Animals; D001201:Ascites / Q000209:etiology / Q000662:veterinary; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000662:veterinary*; D002277:Carcinoma / Q000662:veterinary; D005260:Female; D007565:Jaundice / Q000209:etiology / Q000662:veterinary; D008297:Male; D009362:Neoplasm Metastasis; D001503:Ursidae