title: A long term study on treating velopharyngeal insufficiency by teflon injection.
abstract: Thirty-five individuals with velopharyngeal insufficiency, including eight with failed pharyngeal flaps, were treated with injectable Teflon and followed postoperatively for an average of three years. The patients' speech and voice quality were evaluated pre- and postoperatively, and an outcome was judged successful only if there was total elimination of the preoperative symptoms of hypernasality and inappropriate nasal air emission. All patients were evaluated preoperatively with cinefluorography, and an attempt was made to obtain serial postoperative films in order to determine the stability of the Teflon pad with time. An overall success rate of 74% was achieved. Success for patients with VPI, excluding those patients with pharyngeal flaps was 78%. In treating the failed pharyngeal flap cases we achieved a 62% success rate. The stability of the implanted Teflon was assessed over time as determined from measurements made on patients who received two or more postoperative cine films. Statistical analysis revealed no significant change in thickness of the pad over a period of time. Our conclusions are that with careful case selection, the injectable Teflon procedure is safe, effective and that the implant remains stable with time.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002933:Cineradiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D010160:Palate, Soft / Q000502:physiology; D011138:Polytetrafluoroethylene / Q000008:administration & dosage; D011379:Prognosis; D019736:Prostheses and Implants; D013060:Speech; D014681:Velopharyngeal Insufficiency / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene