A note on association of Bf and glomerulonephritis.
In a study of 86 histologically defined glomerulonephritis patients, a striking association between the BfF allele and glomerulonephritis has been found. There is also an enhanced genetic predisposition to glomerulonephritis in individuals with rare Bf alleles. The role of the chromosome 6 loci in the pathogenesis of the disease is emphasized.
D000483:Alleles; D000917:Antibody Formation; D002869:Chromosome Aberrations; D002877:Chromosomes, Human; D005260:Female; D005819:Genetic Markers; D005921:Glomerulonephritis / Q000235:genetics* / Q000473:pathology; D006680:HLA Antigens; D006801:Humans; D008297:Male
D005819:Genetic Markers; D006680:HLA Antigens