Case-control study of intracranial meningiomas in women in Los Angeles County, California.
A case-control study was conducted among women in Los Angeles County to investigate possible causes of intracranial meningiomas. Questionnaires sought information from patients and from a neighbor of each one on characteristics and past experiences that might be associated with the development of this disease. Information was obtained on 188 matched patient-neighbor pairs. Three primary factors appeared to be associated with meningioma occurrence: 1) a history of head trauma (odds ratio = 2.0, P = 0.01), 2) consumption of certain cured meats (odds ratio = 2.8, P less than 0.01), and 3) exposure to medical and dental diagnostic X-rays to the head. For diagnostic X-rays, the strongest association was with early exposure (less than 20 yr old) to full-mouth dental X-ray series (odds ratio = 4.0, P less than 0.01).
D000367:Age Factors; D001932:Brain Neoplasms / Q000453:epidemiology / Q000209:etiology*; D002140:California; D006259:Craniocerebral Trauma / Q000150:complications; D005260:Female; D005503:Food Additives / Q000009:adverse effects; D006306:Health Surveys; D006801:Humans; D008297:Male; D008579:Meningioma / Q000453:epidemiology / Q000209:etiology*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D009573:Nitrites / Q000009:adverse effects; D011336:Probability; D011861:Radiography, Dental / Q000009:adverse effects; D011795:Surveys and Questionnaires; D014965:X-Rays
D005503:Food Additives; D009573:Nitrites