title: Inhibition of hatching of mouse blastocysts in vitro by various prostaglandin antagonists.
abstract: Hatching of mouse blastocysts in vitro is inhibited by 18,18,20-trimethyl PGE-2, 17,17-dimethyl PGE-2, 8,12-epiPGE-2 and N-dimethylamide PGF-2 alpha, whose activity is between that of 7-oxa-13-prostynoic acid and meclofenamic acid.
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000187:drug effects*; D002478:Cells, Cultured; D015237:Dinoprost / Q000031:analogs & derivatives; D015232:Dinoprostone / Q000031:analogs & derivatives; D051379:Mice; D011448:Prostaglandin Antagonists / Q000494:pharmacology*; D011458:Prostaglandins E / Q000037:antagonists & inhibitors; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology*; D011460:Prostaglandins F / Q000037:antagonists & inhibitors; D011461:Prostaglandins F, Synthetic / Q000494:pharmacology
chemical_list: D011448:Prostaglandin Antagonists; D011458:Prostaglandins E; D011459:Prostaglandins E, Synthetic; D011460:Prostaglandins F; D011461:Prostaglandins F, Synthetic; C032515:8,12-epi-prostaglandin E2; C032516:prostaglandin F2alpha N-dimethylamide; C032514:17,17-dimethylprostaglandin E2; C032513:18,18,20-trimethylprostaglandin E2; D015237:Dinoprost; D015232:Dinoprostone