title: Surgical management and reconstruction of extensive chest wall malignancies.
abstract: Seven patients aged 8 to 77 years underwent massive resection for chest wall malignancies. Two had chondrosarcoma, one recurrent breast cancer, one malignant hemangioepithelioma, one embryonal cell sarcoma, one metastatic osteogenic sarcoma, and one lymphangiosarcoma. The smallest surgical defect was 17 by 19 cm, the largest 35 by 45 cm. Closure was done with Marlex mesh, full-thickness muscle flaps, or free island pectoralis or latissimus dorsi flaps. The rotation of myocutaneous island flaps (bilateral in two patients) greatly facilitated reconstruction. No infection, pulmonary compromise, or operative morbidity or mortality was encountered. The age of the patients and the location or size of the lesions were not significant factors. Designing a surgical strategy which provides adequate full-thickness margins and immediate reconstruction is critically important. Massive chest wall resection for malignancy should be pursued aggressively whenever these lesions are encountered. The operations can be performed safely and can be curative, and the benefits to patients in terms of comfort and prolonged survival justify this extensive surgery.
mesh_terms: D000293:Adolescent; D000368:Aged; D002648:Child; D002813:Chondrosarcoma / Q000601:surgery; D005260:Female; D006390:Hemangioendothelioma / Q000601:surgery; D006801:Humans; D008204:Lymphangiosarcoma / Q000601:surgery; D008297:Male; D008637:Mesenchymoma / Q000601:surgery; D008875:Middle Aged; D012516:Osteosarcoma / Q000601:surgery; D013902:Radiography, Thoracic; D013524:Surgical Flaps; D013526:Surgical Mesh; D013899:Thoracic Neoplasms / Q000556:secondary / Q000601:surgery*; D013903:Thoracic Surgery / Q000379:methods*