The effect of supragingival plaque control on the composition of the subgingival microbial flora in ligature-induced periodontitis in the monkey.
The influence of supragingival plaque control on the subgingival microflora and clinical parameters of ligature-induced periodontitis in the Cynomolgus monkey was investigated. No clinical changes were observed during the six-week experimental period. The total cultivable flora and the proportions of total black-pigmented Bacteroides (BPB) and asaccharolytic black-pigmented Bacteroides decreased significantly in the cleaned test sites as compared to those in the non-cleaned controls. The study suggests that six wk of supragingival plaque control in the presence of periodontal disease may alter the periodontitis-associated microflora in the monkey, but not sufficiently to alter clinical signs of disease in this time period.
D000818:Animals; D001419:Bacteria / Q000166:cytology*; D003773:Dental Plaque / Q000382:microbiology / Q000517:prevention & control*; D005260:Female; D008252:Macaca fascicularis; D010512:Periodontal Index; D010518:Periodontitis / Q000382:microbiology* / Q000473:pathology; D013997:Time Factors