title: The fine structure of epithelial cells in normal and pathological buccal mucosa. IV. Interactions between epithelial cells, lymphocytes, and macrophages.
abstract: In oral lichen planus two types of lymphocytes were found in the lamina propria in the basal and suprabasal layers. The T-cell is identified by the absence of rough-surfaced endoplasmic reticulum in contrast to its extensive development in the B-cell of which various types were identified including plasma cells. Interaction was noted between macrophages, lymphocytes, and epithelial cells. The variability noted in T-cells may arise from sensitization related to phagocytosis of degenerate epithelial cells by macrophages which transfer the immunological information to lymphocytes.
mesh_terms: D004848:Epithelium / Q000648:ultrastructure; D006801:Humans; D008010:Lichen Planus / Q000473:pathology; D008214:Lymphocytes / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure; D008407:Mast Cells / Q000648:ultrastructure; D009059:Mouth Diseases / Q000473:pathology; D009061:Mouth Mucosa / Q000648:ultrastructure*; D010950:Plasma Cells / Q000648:ultrastructure