title: Premature rupture of membranes prior to term: consequences of nonintervention.
abstract: Consequences of nonintervention in the management of prematurely ruptured membranes prior to term were assessed in 143 maternal charts and 145 corresponding infant records during a 2-year period. Patients were hospitalized at bed rest and were not given tocolytics or steroids. Antibiotics were used only when clinical examination indicated infection. Labor was induced in 13 patients. Time in utero was extended 1 week or more in 19% of cases. Maternal infection was identified in 15 women, all of whom recovered. There were 18 neonatal deaths and 4 stillbirths in the series. Three deaths might have been prevented by earlier delivery. Nonintervention in the management of premature rupture of the membranes did not have adverse effects on the incidence of maternal or neonatal infection but was relatively ineffectual in achieving significant extensions of time in utero
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy; D001724:Birth Weight; D001946:Breech Presentation; D005260:Female; D005313:Fetal Death; D005322:Premature Rupture of Fetal Membranes / Q000401:mortality / Q000628:therapy*; D005323:Fetal Monitoring; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy; D013997:Time Factors; D012122:Ventilators, Mechanical
chemical_list: D000900:Anti-Bacterial Agents