Evaluation of liver function tests after administration of aminophenazone.
Known liver function tests (activities of ASAT = L-Aspartate: 2-oxoglutarate aminotransferase, ALAT = L-Alanine: 2-oxoglutarate aminotransferase, GLDH = Glutamate-dehydrogenase, LDH = Lactate-dehydrogenase in serum) are not qualified for detecting minimal histopathological liver alterations induced by aminophenazon.
D000632:Aminopyrine / Q000633:toxicity*; D000818:Animals; D001205:Ascorbic Acid / Q000652:urine; D001711:Biotransformation; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000378:metabolism; D004798:Enzymes / Q000097:blood; D005260:Female; D006626:Hippurates / Q000652:urine; D008111:Liver Function Tests; D008297:Male; D051381:Rats; D013448:Sulfobromophthalein
D004798:Enzymes; D006626:Hippurates; D000632:Aminopyrine; D013448:Sulfobromophthalein; D001205:Ascorbic Acid