[Hirsutism with partial blockage of 3 beta OL hydroxysteroid dehydrogenase (author's transl)].
The findings of normal testosterone, high normal delta 4 androstenedione, normal 17 OH progesterone and raised DHAs in a young girl of 16 who had regular periods and hirsutism made us think of block in 3 HSD. The 17 OH pregnenolone was raised. Dexamethasone (0.5 mg/24 h) treatment was effective for the hirsutism.
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D000293:Adolescent; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006628:Hirsutism / Q000150:complications* / Q000188:drug therapy; D006801:Humans
D003907:Dexamethasone; D015096:3-Hydroxysteroid Dehydrogenases
Hirsutisme avec blocage partiel de la 3 beta OOL hydroxystéroïde déshydrogénase.