Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in guinea pig lymphoid tissue.
Aryl hydrocarbon hydroxylase (AHH) activity was detected in a variety of guinea pig lymphoid tissues and was increased by intradermal or ip administration of 3-methylcholanthrene AHH levels were generally greater in spleen than in lymph node, bone marrow, or thymus. Similar AHH activities were observed in lymphoid tissues from Sewall-Wright inbred strain 2 and strain 13 guinea pigs. Greater AHH activities were associated with peritoneal and alveolar macrophages than with lymph nodes lymphocytes in the absence of mitogens.
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000378:metabolism*; D001579:Benzopyrene Hydroxylase / Q000378:metabolism*; D001853:Bone Marrow / Q000201:enzymology; D006168:Guinea Pigs; D008198:Lymph Nodes / Q000201:enzymology; D008214:Lymphocytes / Q000201:enzymology; D008221:Lymphoid Tissue / Q000187:drug effects / Q000201:enzymology*; D008264:Macrophages / Q000201:enzymology; D008748:Methylcholanthrene / Q000494:pharmacology; D013154:Spleen / Q000201:enzymology; D013950:Thymus Gland / Q000201:enzymology
D008748:Methylcholanthrene; D001579:Benzopyrene Hydroxylase; D001189:Aryl Hydrocarbon Hydroxylases