Antimicrobial activity of a lidocaine preparation.
A preparation commonly used as a local anesthetic in dentistry has been studied for the presence of antimicrobial activity. The solution, 2% Xylocaine®, with 1:100,000 epinephrine, was shown to inhibit the growth of certain organisms and to be cidal to others. Its cidal activity was significantly less than that of 2% Xylocaine without epinephrine (p < .05). Both solutions demonstrated statistically significant cidal activity when compared to controls (p < .005).
D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D001419:Bacteria / Q000187:drug effects*; D004837:Epinephrine / Q000494:pharmacology*; D005069:Evaluation Studies as Topic; D066298:In Vitro Techniques; D008012:Lidocaine / Q000494:pharmacology*
D008012:Lidocaine; D004837:Epinephrine