Healing potential of surgically-induced periodontal osseous defects in animals using mineralized collagen gel xenografts.
This experiment tested the capacity of a calf-skin collagen-mineral gel to induce bone regeneration within surgically-created periodontal defects in one dog and four monkeys. No bone regeneration occurred within 8 to 14 weeks. Healing primarily consisted of soft connective tissue formation and re-epithelialization. Notched defects on root surfaces did not repair with cementum and were always foci of inflammation.
D000818:Animals; D001861:Bone Regeneration; D002130:Calcium Phosphates / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D004285:Dogs; D005782:Gels; D008252:Macaca fascicularis; D010510:Periodontal Diseases / Q000473:pathology / Q000601:surgery*; D019736:Prostheses and Implants; D014183:Transplantation, Heterologous
D002130:Calcium Phosphates; D005782:Gels; D003094:Collagen