[Behaviour of bone marrow and splenic hemopoietic stem cells following administration of anthracyclines].
The effect of Adriamycin and 4-Eip-Adriamycin was studied on CFUs, CFUc, CFUe of murine bone marrow and spleen. Differences among the bone marrow stem cells and the spleen stem cells have been observed. It seems possible to explain some of these differences admitting a process of redistribution from the bone marrow to the spleen.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D004317:Doxorubicin / Q000494:pharmacology*; D015251:Epirubicin; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D051379:Mice; D013154:Spleen / Q000166:cytology* / Q000187:drug effects; D013237:Stereoisomerism
D015251:Epirubicin; D004317:Doxorubicin
Comportamento delle cellule staminali emopoietiche midollari e di quelle spleniche dopo somministrazione di antraciclinici.