title: Nutritional toxicological studies with Lannate: interactions with caffeine and ethanol.
abstract: Effects of the ingestion of Lannate (200 mg/kg diet), caffeine (30 mg% aqueous solution) and ethanol (10% aqueous solution) both separately as well as the ingestion of Lannate with caffeine or ethanol were studied in R/Amsterdam rats. Response to the combined administration of Lannate and caffeine produced evidence of interactions only in female rats. The combined ingestion of Lannate and ethanol resulted in some interactions both in female and male rats, however, sex differences were apparent regarding certain parameters.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001921:Brain / Q000201:enzymology; D002110:Caffeine / Q000494:pharmacology*; D004347:Drug Interactions; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006128:Growth / Q000187:drug effects; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000201:enzymology; D008297:Male; D008724:Methomyl / Q000633:toxicity*; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007306:Insecticides; D014280:Triglycerides; D008724:Methomyl; D002110:Caffeine; D000431:Ethanol