Observations on nuclear protrusions and the length of long arms of abnormal chromosomes in malignancy.
The relationship between the appearance of nuclear protrusions and the length of the long arms of large abnormal chromosomes in preparations from cancer cells is described. Nuclear protrusions were found consistently in all cases in which there were cells with marker chromosomes having long arms at least as long as 85% of the whole of chromosome no. 1.
D000368:Aged; D002467:Cell Nucleus / Q000648:ultrastructure*; D002503:Centromere / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000473:pathology*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000235:genetics / Q000648:ultrastructure*; D014178:Translocation, Genetic