Prescribing patterns for epilepsy.
All prescriptions for anticonvulsants written over a four month period for patients in the Wellington area were identified. Of 1479 patients receiving anticonvulsants, 139 were suspected of receiving medication for conditions other than epilepsy. The prevalence of treated epilepsy in Wellington is 4.1 per 1000 population. Thirty-eight percent of patients were on multiple anticonvulsants, which compares favourably with reports of excessive polypharmacy in Europe. However, there was excessive reliance on standard anticonvulsant doses, given at frequent intervals regardless of probable rates of metabolism. Failure of compliance, as assessed by the time intervals between collection of drugs, was shown by 21 percent of patients.
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000600:supply & distribution; D002648:Child; D011307:Drug Prescriptions; D004359:Drug Therapy, Combination; D004363:Drug Utilization; D004827:Epilepsy / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D009426:Netherlands; D009520:New Zealand; D009664:Norway; D010349:Patient Compliance; D010634:Phenobarbital / Q000008:administration & dosage / Q000600:supply & distribution / Q000627:therapeutic use; D010672:Phenytoin / Q000008:administration & dosage / Q000600:supply & distribution / Q000627:therapeutic use; D010821:Physicians, Family
D000927:Anticonvulsants; D010672:Phenytoin; D010634:Phenobarbital