Significance of a (4;11) translocation in acute lymphoblastic leukemia.
This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented.
D002905:Chromosomes, Human, 4-5; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics*; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000151:congenital / Q000235:genetics*; D014178:Translocation, Genetic