[Treatment of acute leukemias in adults. I. Results of intensive chemotherapy of 106 patients with acute leukemia].
In a period of 5 years 106 patients with acute leukemia were treated (93 with acute nonlymphoblastic leukemia and 13 with acute lymphoblastic leukaemia. Four therapeutic programmes were used. Complete remission (CR) was achieved in 41% of patients, including 37% of those with acute non-lymphoblastic leukaemia and 77% with acute lymphoblastic leukaemia. The per cent of remissions obtained using different programmes was similar. During intensive induction treatment 22% of patients died, mainly of infections and bleeding tendency.
D000208:Acute Disease; D000328:Adult; D003422:Critical Care / Q000379:methods; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D007938:Leukemia / Q000188:drug therapy* / Q000401:mortality; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000401:mortality; D015122:Mercaptopurine / Q000008:administration & dosage; D011241:Prednisone / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
D003561:Cytarabine; D014750:Vincristine; D003520:Cyclophosphamide; D015122:Mercaptopurine; D011241:Prednisone; D006918:Hydroxyurea; D003630:Daunorubicin
Leczenie ostrych białaczek u dorosłych. I. Wyniki intensywnej chemioterapii u 106 chorych z ostra białaczka.