title: Phenytoin-induced gingival overgrowth control in severely retarded children.
abstract: Nineteen severely retarded children were studied to evaluate distribution, severity and control of phenytoin-induced gingival overgrowth (PIGO). Observations included the Plaque Index, the Gingival Index and the PIGO Index. Eighteen of these patients had gingival overgrowth with 47% having the severest type of involvement and all having severe overgrowth in the posterior regions. Elimination of topical, oral contact of phenytoin did not appear to alter gingival overgrowth. Use of SnF2 as an antiplaque agent significantly decreased plaque and overgrowth scores. Use of an electric toothbrush quite significantly decreased gingival inflammation, plaque scores and gingival overgrowth.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003773:Dental Plaque / Q000473:pathology / Q000517:prevention & control; D005881:Gingiva / Q000187:drug effects*; D005885:Gingival Hyperplasia / Q000139:chemically induced / Q000628:therapy*; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology*; D010512:Periodontal Index; D010672:Phenytoin / Q000009:adverse effects*; D014002:Tin Fluorides / Q000627:therapeutic use; D014099:Toothbrushing / Q000295:instrumentation
chemical_list: D014002:Tin Fluorides; D010672:Phenytoin