title: Linkage and chromosomal studies in congenital cataract.
abstract: The methods used in linkage and chromosomal studies in congenital cataract are described. These are: classical pedigree analysis with the detection of recombinants among the offspring of informative matings, and somatic cell hybridization. The recently developed methods using recombinant DNA techniques are briefly mentioned.
mesh_terms: D002386:Cataract / Q000151:congenital* / Q000235:genetics; D002874:Chromosome Mapping; D003434:Crossing Over, Genetic; D004274:DNA, Recombinant; D008040:Genetic Linkage; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure; D010375:Pedigree
chemical_list: D004274:DNA, Recombinant