title: Gastrectomy in siblings with Christmas disease (hemophilia B).
abstract: Gastrointestinal hemorrhage is regarded as one of the commonest clinical manifestations of classic hemophilia and Christmas disease. Although major surgery is usually avoided in such cases, recently we had 2 cases of Christmas disease in siblings who had undergone a successful gastrectomy and concomitant administration of a concentrated preparation of factor IX. In addition, findings in 7 other Japanese patients with hemophilia who underwent gastrectomy are discussed.
mesh_terms: D001803:Blood Transfusion; D005164:Factor IX / Q000008:administration & dosage / Q000627:therapeutic use; D005743:Gastrectomy; D006471:Gastrointestinal Hemorrhage / Q000601:surgery / Q000628:therapy; D002836:Hemophilia B / Q000235:genetics / Q000601:surgery* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000601:surgery
chemical_list: D005164:Factor IX