Structural studies of the capsular polysaccharide elaborated by Haemophilus influenza type d.
The structure of the capsular polysaccharide elaborated by Haemophilus influenzae type d has been investigated, methylation analysis and n.m.r. spectrometry being the principal methods used. It is concluded that the polysaccharide is composed of repeating units having the structure: leads to 4)-beta-D-GlcpNAc-(1 leads to 3)-beta-D-ManpNAcA-(1 leads to. In addition, single residues of L-alanine, L-serine, or L-threonine, in the proportions 2:2:1, are linked, through their amino groups, to C-6 of the 2-acetamido-2-deoxy-beta-D-mannopyranosyluronic acid residues. The degree of substitution (75-85%) varies for different preparations.
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006193:Haemophilus influenzae / Q000276:immunology*; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D011135:Polysaccharides, Bacterial
D011135:Polysaccharides, Bacterial