title: Histiocytosis X: treatment with topical nitrogen mustard.
abstract: The case histories of two elderly patients with cutaneous histiocytosis X treated topically with nitrogen mustard are presented. The cutaneous lesions cleared within 2 to 3 weeks, and remission was maintained with daily topical administration of nitrogen mustard. The clinical impression of improvement was substantiated by light and electron microscopic studies prior to and after therapy.
mesh_terms: D000287:Administration, Topical; D000368:Aged; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008466:Mechlorethamine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D008466:Mechlorethamine