Mycosis fungoides d'emblée: a rare presentation of cutaneous T-cell lymphoma.
A case of the d'emblée variant of mycosis fungoides is presented to confirm the validity of this rare variant of cutaneous T-cell lymphoma. The patient had rapidly progressing cutaneous tumors of mycosis fungoides with no internal organ or nodal involvement at the onset of the disease. This was confirmed at a laparotomy, which was done to remove a uterine leiomyoma. The classic light microscopy was confirmed by electron microscopy. Postmortem findings showed a remarkable degree of "epitheliotropism." The d'emblée form of mycosis fungoides has been disputed by some who argue that these cases represent a lymphoma that begins elsewhere and has secondary skin involvement. In this patient there was an opportunity, within a few weeks of the onset of the problem, to do an extensive staging work-up, including laparotomy. No evidence of internal lymphoma was found.
D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery; D008854:Microscopy, Electron; D009182:Mycosis Fungoides / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D013601:T-Lymphocytes / Q000648:ultrastructure; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery