[Effect of serum against hematopoietic stem cells (RAMBS) on self-maintaining cells of Rauscher erythroleukemia].
The spleen colony assay was used to study the effect of rabbit antimouse brain serum (RAMBS) on erythroleukemic colony-forming cells (ECFC). RAMBS was shown to specifically inactivate hemopoietic stem cells (CFU-S) and to have no influence on ECFC growth. Absorption of RAMBS by erythroleukemic cells did not inhibit its anti-CFU-S activity. It is suggested that CFU-S and ECFC differ in the antigenic spectrum.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D006824:Hybridization, Genetic; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D008806:Mice, Inbred AKR; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface
Deĭstvie syvorotki protiv stvolovykh krovetvornykh kletok (RAMBS) na kletki samopodderzhivaiushchikhsia shtammov éritroleĭkoza Raushera.