Eosinophilic pleural effusion with high anti-DNA activity as a manifestation of systemic lupus erythematosus.
A patient, known to have systemic lupus erythematosus (SLE), presented with an eosinophilic pleural effusion. It is believed that SLE was the cause of her pleural effusion as increased levels of anti-DNA activity were found in the pleural fluid. Eosinophilic pleural effusion is a previosuly unreported observation in SLE patients (so far as the authors are aware), and the existence of increased anti-DNA activity in the pleural fluid may have value as an additional aid in the diagnosis of this disease.
D000974:Antibodies, Antinuclear / Q000032:analysis; D004247:DNA / Q000276:immunology; D004804:Eosinophils; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D010996:Pleural Effusion / Q000097:blood / Q000209:etiology* / Q000276:immunology
D000974:Antibodies, Antinuclear; D004247:DNA