Ticarcillin bioassay.
An accurate, plate diffusion bioassay for ticarcillin, utilizing the fast-replicating Beneckea natriegens and 4% salt agar, is described in this report. Zones of inhibition were well defined after 3 h, and the limit of sensitivity was around 5.0 mug/ml. The assay is simple to carry out, and duplicate assays can be performed on as little as 40 mul of serum.
D001681:Biological Assay; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D005839:Gentamicins / Q000032:analysis; D006801:Humans; D010406:Penicillins / Q000032:analysis*; D013982:Ticarcillin / Q000008:administration & dosage / Q000032:analysis* / Q000097:blood; D014031:Tobramycin / Q000032:analysis; D014733:Vibrio / Q000187:drug effects / Q000254:growth & development
D003470:Culture Media; D005839:Gentamicins; D010406:Penicillins; D013982:Ticarcillin; D014031:Tobramycin