[Endolaryngeal surgery using highly concentrated human fibrinogen as tissue adhesive. Further trials with fibrin glue].
The use of an activated human fibrinogen concentrate in endolaryngeal surgery has been performed in 31 cases without the conventional suturing technique. Among the satisfactory results of fibrin gluing in endolaryngeal regions are optimum healing tendency due to haemostasis, lack of tissue irritation and toxicity. Persistence and highly adhesive properties were studied in experimental investigations in the dog following motoric stress of clot-sutured vocal cords.
D000328:Adult; D000818:Animals; D004285:Dogs; D004338:Drug Combinations / Q000494:pharmacology; D005176:Factor XIII / Q000494:pharmacology; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000494:pharmacology; D006467:Hemophilia A / Q000628:therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery; D007830:Larynx / Q000601:surgery*; D008297:Male; D011127:Polyps / Q000601:surgery; D013917:Thrombin / Q000494:pharmacology; D014014:Tissue Adhesives / Q000494:pharmacology; D014826:Vocal Cord Paralysis / Q000601:surgery; D014827:Vocal Cords / Q000601:surgery; D014945:Wound Healing
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin
Endolaryngeale Eingriffe unter Verwendung hochkonzentrierten humanen Fibrinogens als Gewebekleber. Weitere Erfahrungen mit dem Fibrinkleber.