Animal pharmacology of oxapadol (MD 720111), a new non-narcotic analgesic.
Oxapadol is a non-narcotic analgesic with an unusual chemical structure. It possesses analgesic activity in 4 species similar to that of other non-narcotic reference analgesics. It also shows antipyretic and antiinflammatory effects and in the analgesic dose range is devoid of undesirable neurological, gastro-intestinal and cardiovascular side-effects.
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001381:Azepines / Q000494:pharmacology*; D001562:Benzimidazoles / Q000009:adverse effects / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D051379:Mice; D010077:Oxazepines / Q000009:adverse effects / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001381:Azepines; D001562:Benzimidazoles; D010077:Oxazepines; C023515:oxapadol