Antigen-trapping cells in Peyer's patches of the rat.
Peyer's patches (PP) of rats were studied with immunocytochemical, enzyme cytochemical, and electron microscopic techniques. Special attention was paid to the non-lymphoid antigen-trapping cells. Follicular dendritic cells, morphologically comparable to those present in spleen and lymph nodes, were found in the germinal centers of PP. Ia-positive cells with the morphological characteristics of interdigitating cells were seen in the interfollicular area. Thus, both types of antigen-presenting cells, characteristic for B- and T-cell areas, respectively, were present in PP.
D000818:Animals; D000941:Antigens / Q000032:analysis*; D002454:Cell Differentiation; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008221:Lymphoid Tissue / Q000276:immunology*; D008264:Macrophages / Q000201:enzymology / Q000276:immunology; D012157:Mononuclear Phagocyte System / Q000166:cytology / Q000201:enzymology / Q000276:immunology; D010581:Peyer's Patches / Q000166:cytology / Q000201:enzymology / Q000276:immunology*; D051381:Rats; D011919:Rats, Inbred Strains
D000941:Antigens; D000949:Histocompatibility Antigens Class II; D007075:Immunoglobulin M