title: Yersinia enterocolitica biotype I. Diarrhoea and episodes of HLA B27 related ocular and rheumatic inflammatory disease in South-East England.
abstract: Yersinia enterocolitica biotype I were isolated from faeces of 16% of 56 consecutive patients with diarrhoea or gastrointestinal symptoms and 2.8% of 109 healthy controls (p less than 0.01). Similar Yersinia biotypes were isolated from 4% of samples from 86 rheumatoid arthritis patients and 4.5% of samples from 140 ankylosing spondylitis patients examined regularly over an 8-month period. These results suggest that Yersinia enterocolitica biotype I are regular but infrequent inhabitants of the human gastrointestinal tract in south-east England. The increased isolation rate of these microorganisms from patients with enteric disease and from patients with exacerbations of HLA B27-related arthritic and ocular inflammatory disease justifies further investigations.
mesh_terms: D000328:Adult; D001172:Arthritis, Rheumatoid / Q000276:immunology / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology*; D004739:England; D005243:Feces / Q000382:microbiology; D006680:HLA Antigens / Q000276:immunology; D015796:HLA-B27 Antigen; D006801:Humans; D013167:Spondylitis, Ankylosing / Q000276:immunology / Q000382:microbiology; D014605:Uveitis / Q000276:immunology / Q000382:microbiology*; D015008:Yersinia enterocolitica
chemical_list: D006680:HLA Antigens; D015796:HLA-B27 Antigen