title: [Effect of motropin and naloxone on electroacupuncture analgesia].
abstract: It was demonstrated in experiments on awake rabbits that electroacupuncture increases the pain threshold (the tail-flick-test) and suppresses the second positive wave of evoked potential in the somatosensory cortex in response to nociceptive electrocutaneous stimulation. Naloxone, the typical antagonist of narcotic analgetics, in doses of 0.05-0.1 mg/kg completely blocks the effects induced by electroacupuncture. The similar effects were produced by motropin, a new antagonist of narcotic analgetics, belonging to the tropan series, administered in doses of 10-20 mg/kg.
mesh_terms: D015670:Acupuncture Therapy / Q000379:methods*; D000818:Animals; D004599:Electric Stimulation Therapy; D005073:Evoked Potentials, Somatosensory; D005260:Female; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D059408:Pain Management; D011817:Rabbits; D011930:Reaction Time; D014326:Tropanes / Q000494:pharmacology*
chemical_list: D009292:Narcotic Antagonists; D014326:Tropanes; D009270:Naloxone; C033197:motropin
vernacular_title: Vliianie motropina i naloksona na élektroakupunkturnuiu anal'geziiu.