Delayed hemolytic transfusion reaction caused by anti-Jsb in a Js(a+b+) patient.
A 39-year-old multiparous woman developed a mixed field positive direct antiglobulin test within 15 days of receiving four units of crossmatch compatible red blood cells. Anti-Jsb was demonstrable in both the serum and the eluate. The case was further complicated by the fact that the patient's pretransfusion red blood cells typed as Js(b+). Serologic studies demonstrated that this was a case of allo-anti-Jsb in a Js(b+) patient which provides evidence of heterogeniety of the Js locus.
D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology*; D015478:Antigens, Heterophile / Q000235:genetics; D001789:Blood Group Antigens / Q000276:immunology*; D001787:Blood Group Incompatibility / Q000209:etiology; D003298:Coombs Test; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis; D007626:Kell Blood-Group System / Q000235:genetics / Q000276:immunology*; D011247:Pregnancy; D013997:Time Factors; D065227:Transfusion Reaction
D015478:Antigens, Heterophile; D001789:Blood Group Antigens; D007518:Isoantibodies; D007626:Kell Blood-Group System