title: Pyridinium-2-azo-p-dimethylaniline chromophore, a new chromogenic cephalosporin for rapid beta-lactamase testing.
abstract: A new chromogenic cephalosporin, pyridinium-2-azo-p-dimethylaniline chromophore, was evaluated for use in a rapid paper strip or tube test for the detection of beta-lactamases from a variety of microorganisms. A 1-min pyridinium-2-azo-p-dimethylaniline chromophore paper strip test was found to be a convenient and accurate method for the detection of beta-lactamase-producing strains of Haemophilus influenzae and Neisseria gonorrhoeae, although it could not be relied upon to detect beta-lactamases produced by staphylococci, enteric organisms, or Bacteroides fragilis.
mesh_terms: D001419:Bacteria / Q000201:enzymology*; D002511:Cephalosporins; D002863:Chromogenic Compounds; D004755:Enterobacteriaceae / Q000201:enzymology; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D002511:Cephalosporins; D002863:Chromogenic Compounds; C034313:pyridine-2-azo-4-dimethylaniline cephalosporin; D001618:beta-Lactamases