Quantitation of T-lymphocyte subsets in human bronchus mucosa.
Cells were isolated from human bronchus mucosa, and characterized according to a surface marker for sheep erythrocytes (T cells), to the presence of membrane associated immunoglobulin (B cells), and to the capacity to phagocytose latex particles (macrophages). The T lymphocytes were further characterized according to their capacity to bind to the Fc fragment of IgG, IgM, and IgA (T gamma, T mu, and T alpha cells, respectively). Less t alpha cells were found in acutely inflamed mucosa than in mucosa obtained from patients with chronic inflammatory, or neoplastic disease (p = less than 0.001).
D000911:Antibodies, Monoclonal; D001980:Bronchi / Q000166:cytology* / Q000276:immunology; D001982:Bronchial Diseases / Q000473:pathology; D006801:Humans; D009092:Mucous Membrane / Q000166:cytology / Q000276:immunology; D011961:Receptors, Fc; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000145:classification*
D000911:Antibodies, Monoclonal; D011961:Receptors, Fc