[Gelatinous drop-like dystrophy of the cornea (primary amylosis) (author's transl)].
Two cases of gelatinous drop-like dystrophy of the cornea in young North-African (Algeria, Tunisia) subjects are reported. Clinical examination revealed characteristic subepithelial gelatinous drops in the cornea. Histology showed the amyloid nature of the subepithelial deposits, their fibrillary from being demonstrated on ultrastructural examination. Lamellar keratoplasty did not prevent recurrences. A pathogenic hypothesis is suggested involving a role of epithelial induction in the fibroblast development.
D000328:Adult; D000686:Amyloidosis / Q000473:pathology*; D000688:Amylose / Q000378:metabolism; D003315:Cornea / Q000648:ultrastructure; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D004848:Epithelium / Q000648:ultrastructure; D006801:Humans; D008297:Male
D000688:Amylose
Dystrophie gélatineuse en goutte de la cornée. Amylose primitive.