Peripheral blood T lymphocytes in patients with duodenal ulcers treated with cimetidine.
The influence of cimetidine on the numbers of circulating T lymphocytes was studied in 24 patients with duodenal ulcer treated with cimetidine. The patients were divided into two groups according to the way of cimetidine administration and T lymphocytes were measured during treatment. No significant difference in the numbers of T lymphocytes was found in both groups of patients suggesting that cimetidine given therapeutically has no effect on circulating T lymphocytes.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002927:Cimetidine / Q000008:administration & dosage / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007275:Injections, Intravenous; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000187:drug effects*
D006146:Guanidines; D002927:Cimetidine