title: Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase.
mesh_terms: D000970:Antineoplastic Agents; D003856:Deoxyuracil Nucleotides / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D003857:Deoxyuridine / Q000031:analogs & derivatives / Q000494:pharmacology; D005468:Fluorodeoxyuridylate / Q000494:pharmacology; D005472:Fluorouracil / Q000378:metabolism / Q000494:pharmacology; D008727:Methotrexate / Q000494:pharmacology; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D011485:Protein Binding; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D014498:Uracil / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D003856:Deoxyuracil Nucleotides; D005468:Fluorodeoxyuridylate; D014498:Uracil; D008780:Methyltransferases; D013940:Thymidylate Synthase; D005472:Fluorouracil; D003857:Deoxyuridine; D008727:Methotrexate