Clinical and immunological associations in myasthenia gravis. 1: Autoantibodies.
Associations between female sex, HLA B8, positive anti-thyroid microsomal antibody and, to a lesser extent, antinuclear antibody were seen in 34 patients with myasthenia gravis. This supports the concept that the disease is heterogeneous. Anti-DNA antibodies, which were present in 62% of the patients, did not show such associations.
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis*; D004247:DNA / Q000276:immunology; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D008861:Microsomes / Q000276:immunology; D009157:Myasthenia Gravis / Q000276:immunology*; D010641:Phenotype; D013961:Thyroid Gland / Q000276:immunology
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D006680:HLA Antigens; D004247:DNA