[B cells and serum immunoglobulins in patients with breast pathology].
The authors study the amount of B cells and serum immunoglobulins in patients with mammary cancer or fibrocystic disease. They indicate that a decreasing in B cells and IgG, and an increasing in IgA are associated with a better prognosis. There is an inverse relation between the level of serum IgG and the blastic transformation of T cells by PHA, what is an indirect measure of the circulating IgG immune complexes. The presence of B cells with IgG in their surfaces makes worse the prognosis.
D000328:Adult; D000912:Antibodies, Neoplasm / Q000032:analysis*; D001402:B-Lymphocytes / Q000276:immunology*; D001941:Breast Diseases / Q000276:immunology*; D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology; D005260:Female; D005348:Fibrocystic Breast Disease / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008875:Middle Aged; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology
D000912:Antibodies, Neoplasm; D007070:Immunoglobulin A; D007074:Immunoglobulin G
Estudio de células B e inmunoglobulinas séricas en enfermas con patología mamaria.