Report of a case of non-Hodgkin's lymphoma of large multilobated cell type with B-cell origin.
Large multilobated nuclei lymphoma is a rare entity that is characterized morphologically by large neoplastic elements with prominent nuclear lobations and clinically by a predilection for extranodal sites and a favorable prognosis. According to the data collected to date, the neoplasia is thought to be of T-cell origin. The authors describe the clinical, morphologic and immunohistochemical findings of a case of non-Hodgkin's lymphoma with large multilobated nuclei that showed a definite B-lymphocyte origin.
D000368:Aged; D001402:B-Lymphocytes; D002467:Cell Nucleus / Q000648:ultrastructure; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron