Lymphocyte populations in chronic active liver disease: in vitro effect of levamisole on T-lymphocyte populations.
Changes of T and B lymphocyte populations have been studied in chronic active hepatitis and liver cirrhosis. It was found that E rosette-forming T lymphocyte counts were significantly lower in this group of diseases than in the controls. The B cell count did no change significantly as compared to the controls. Incubation with levamisole was followed by a significant increase in active E rosette-forming and total T-cell counts. The authors have appraised the experimental results by comparison to published findings.
D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D002908:Chronic Disease; D005260:Female; D006525:Hepatitis, Viral, Human / Q000097:blood* / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D007958:Leukocyte Count; D007978:Levamisole / Q000494:pharmacology*; D008103:Liver Cirrhosis / Q000097:blood* / Q000276:immunology; D008212:Lymphocyte Depletion; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects*
D007978:Levamisole