Human T lymphocytes subpopulation as defined by alloantigens and FC receptors a comparative analysis.
Human peripheral T cells were fractionated in accordance to their surface receptors for G or M immunoglobulins and analyzed for their reactivity with alloantisera obtained by planned immunization involving HLA-A and HLA-B compatible individuals. These alloantisera were previously shown to recognized polymorphic structure exclusively expressed on T cells. Although the majority of the alloantisera analyzed reacted with different proportions of both T(M) and T(G) populations, some antisera specifically recognized surface structure restricted to either T(M) or T(G) lymphocytes. The various alloantisera consistently reacted with a fraction only of T(G) and T(M) cells, this indicating that these T cell subsets can be further fractionated in accordance to the expression of the alloantigenic determinants recognized by these antisera.
D000818:Animals; D002469:Cell Separation; D006680:HLA Antigens; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D007518:Isoantibodies; D007519:Isoantigens; D011817:Rabbits; D011897:Random Allocation; D011961:Receptors, Fc; D013601:T-Lymphocytes / Q000145:classification*
D006680:HLA Antigens; D007106:Immune Sera; D007518:Isoantibodies; D007519:Isoantigens; D011961:Receptors, Fc