[Participation of monoamines in the recuperative responses of the central nervous system following experimental injury to the anterior portions of the cerebral cortex].
The role of biogenic amines (serotonine and noradrenalin) in the compensatory recovery processes was studied by means of conditioned reflexes in chronic experiments on rats after extirpation of the forebrain cortex. The recovery reactions are shown to proceed in the presence of significant shifts in the level of biogenic amines. Injection of 5-hydroxytryptophan to the operated on animals promotes rapid recovery of disturbed conditioned reflexes. It is suggested tht the increased serotonin brain level raises its compensatory potencies.
D006916:5-Hydroxytryptophan / Q000032:analysis; D000818:Animals; D001923:Brain Chemistry; D001933:Brain Stem / Q000032:analysis; D002540:Cerebral Cortex / Q000032:analysis; D005625:Frontal Lobe / Q000293:injuries*; D007031:Hypothalamus / Q000032:analysis; D008297:Male; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats; D012701:Serotonin / Q000032:analysis*
D012701:Serotonin; D006916:5-Hydroxytryptophan; D009638:Norepinephrine
Uchastie monoaminov v vosstanovitel'nykh reaktsiiakh tsentral'noĭ nervnoĭ sistemy pri éksperimental'nom povrezhdenii perednikh otdelov kory golovnogo mozga.