A lupus-like syndrome due to lbuprofen hypersensitivity.
A patient with degenerative joint disease with an unusual hypersensitivity reaction to ibuprofen is described. The patient developed transient fever, myalgia polyarthritis and rash following each of 4 exposures to the drug. These manifestations were associated with positive Coombs' and FANA tests.
D000974:Antibodies, Antinuclear; D001799:Blood Sedimentation; D003298:Coombs Test; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects* / Q000627:therapeutic use; D007592:Joint Diseases / Q000188:drug therapy; D008180:Lupus Erythematosus, Systemic / Q000209:etiology*; D008875:Middle Aged; D013577:Syndrome
D000974:Antibodies, Antinuclear; D007052:Ibuprofen