Quality of survival in histiocytosis X: a Southwest Oncology Group study.
Sixty children survived for five years after the diagnosis of histiocytosis X. Serious disabilities were seen in 50% of children whose disease involved soft tissue and bone. Late deaths from pulmonary failure were associated with opportunistic infections in two cases. Future treatment approaches must weigh the risks of therapy-related complications against the probability of significant disability if the disease continues for many years.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy / Q000401:mortality / Q000534:rehabilitation*; D006801:Humans; D007223:Infant; D011379:Prognosis; D011788:Quality of Life; D014481:United States