title: HLA-DR typing in 58 cases of rheumatoid arthritis.
abstract: The results of a previous study led us to believe that the association of HLA-DR4 and rheumatoid arthritis could be of particular interest in our region. In this work we typed 58 caucasoid patients in the Marseilles area by microlymphocytotoxicity assay in B-cells. HLA-DR4 was found to be at the same level as that observed by the authors in the 8th Workshop of histocompatibility (1980) (X2:32.36, P less than 0.001) and very high in the seropositive patients (61.5 per cent). No correlation with sex was observed. We again found a low frequency of HLA-DR4 (15.8 per cent) in our controls.
mesh_terms: D001172:Arthritis, Rheumatoid / Q000276:immunology*; D005260:Female; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D012217:Rheumatoid Factor / Q000276:immunology; D012737:Sex Factors
chemical_list: D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D012217:Rheumatoid Factor