[Cell-mediated immunity study by skin testing in 129 critically ill patients (author's transl)].
Delayed hypersensitivity skin testing was performed in 129 critically ill patients. Six intradermal antigens were used: tuberculin, candidin, varidase, epidermophytin, trichophytin and CCB (a polyvalent microbial vaccine from the Pasteur Institute). The response was judged as positive when one test or more were positive. Patients were devided in four groups: group A (40 cases): non-infected patients, a priori without immunodeficiency; group B (14 cases); suspected of immunodeficiency (cancers, hemopathies, collagen diseases receiving corticosteroids); group C (24 cases): decompensated chronic respiratory insufficienceis; group D (50 cases): overwhelming sepsis (septicaemias, septic acute respiratory distress syndromes, thoracic empyemas, purulent meningitis, peritonitis, mediastinitis). A significant diminution of delayed hypersensitivity was observed in groups B, C and D. No relation was found between delayed hypertensitivity and prognosis in groups C and D.
D000368:Aged; D003422:Critical Care; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis; D007154:Immune System Diseases / Q000175:diagnosis; D007111:Immunity, Cellular; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012882:Skin Tests / Q000379:methods*; D014374:Tuberculin Test
Etude de l'immunité à médiation cellulaire par les tests cutanés chez 129 malades d'un service de réanimation polyvalente.