title: Transneuronal vestibular afferent influence on the nodular molecular layer synaptogenesis.
abstract: The effect of vestibular afferent deprivation on the synaptogenesis of the nodular molecular layer has been studied quantitatively. No detectable effect on the time sequence of the development of the molecular layer and the external granular layer was found. Only around hatching a significantly reduced synaptic profile density was found in otocyst-deprived chickens on both halves of the nodulus. This effect can most easily be explained by the assumption of an anterograde transient transneuronal influence of vestibular afferents on the ability of parallel fibers to form synapses.
mesh_terms: D000818:Animals; D002525:Cerebellar Cortex / Q000196:embryology* / Q000648:ultrastructure; D002642:Chick Embryo; D008433:Mathematics; D051379:Mice; D008854:Microscopy, Electron; D013569:Synapses / Q000502:physiology* / Q000648:ultrastructure; D014722:Vestibule, Labyrinth / Q000502:physiology*