title: Immune disease and HLA associations with myasthenia gravis.
abstract: In the late 1950's laboratory and clinical evidence suggested that myasthenia gravis was an autoimmune disorder. Since then a voluminous literature has developed documenting the many immunological abnormalities that occur in this condition. Recent findings point to a central disorder of immunoregulation. It is postulated that the disease occurs as a result of host genetic and environmental influences-the latter being, as yet unidentified and possibly a virus.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004195:Disease Models, Animal; D004200:Diseases in Twins; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009157:Myasthenia Gravis / Q000235:genetics / Q000276:immunology*; D011247:Pregnancy; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D001323:Autoantibodies; D006680:HLA Antigens