[Formation of antibiotic JI-20B by a culture of Streptomyces flavovirens].
An actinomycetous culture having an antibiotic action on gram-positive and gram-negative bacteria was isolated from a soil sample collected in the region of the Balaton Lake. As a result of the taxonomic study the culture was classified as Str. flavovirens. Waksman, Henrici (1948). Examination of antimicrobial properties of the antibiotic and chromatographic and mass-spectroscopic studies allowed one to classify it as an aminoglycoside belonging to the gentamicin group. The antibiotic was designated as J120-B. Until recently such antibiotics were known to be produced only by Micromonospora.
D003470:Culture Media / Q000378:metabolism; D004352:Drug Resistance, Microbial; D005839:Gentamicins / Q000096:biosynthesis*; D008826:Microbial Sensitivity Tests; D012988:Soil Microbiology; D013211:Staphylococcus aureus / Q000187:drug effects; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*
D003470:Culture Media; D005839:Gentamicins; C030244:antibiotic JI 20B
Obrazovanie antibiotika J120-B kul'turoĭ Streptomyces flavovirens.