title: Assignment of the gene coding for human catalase to the short arm of chromosome 11.
abstract: Human and murine catalases can be separated electrophoretically as single bands of different mobility. In man-mouse somatic cell hybrids, however, detection of human catalase is precluded by the complexity of banding patterns resulting from interference of a catalase-modifying enzyme activity. We have identified human catalase in hybrid clones by Laurel electrophoresis employing a specific anti-human catalase antibody, and by exploiting heat stability differences. Catalase co-segregates with LDH A and is probably located on the short arm of chromosome 11.
mesh_terms: D000818:Animals; D000906:Antibodies; D000918:Antibody Specificity; D002374:Catalase / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X / Q000648:ultrastructure; D004586:Electrophoresis; D006358:Hot Temperature; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D051379:Mice; D011489:Protein Denaturation
chemical_list: D000906:Antibodies; D002374:Catalase