[Glutathione peroxidase activity of frog eye pigment epithelium].
A highly active glutathione peroxidase (80% of which is localized in the water-soluble fraction) was detected in frog eye pigment epithelium tissue. It was shown that more than 75% of the glutathione peroxidase activity of the pigment epithelium tissue is bound to the Se-dependent enzyme. The Km values for glutathione and tret-butyl hydroperoxide were determined. It was found that Se, being a constituent of the melanoprotein granules, is not coupled to glutathione peroxidase.
D000818:Animals; D005979:Glutathione Peroxidase / Q000378:metabolism*; D007700:Kinetics; D010544:Peroxidases / Q000378:metabolism*; D010857:Pigment Epithelium of Eye / Q000201:enzymology*; D011896:Rana temporaria; D012643:Selenium
D010544:Peroxidases; D005979:Glutathione Peroxidase; D012643:Selenium
Glutationperoksidaznaia aktivnost' tkani pigmentonogo epiteliia glaza liagushki.