Retinal 's' antigen disease in rats.
The form of experimental allergic uveoretinitis induced by sensitization with retinal 's' antigen in rats actually begins as a pars planitis and juxtapapillary choroiditis. Retinal inflammation develops at the middle limiting vascular layer of the retina and extends outward with focal destruction of photoreceptors and inward as a perivasculitis of small retinal vessels. Extensive choroiditis is a late development in severely diseased animals. Significant strain differences in susceptibility to disease were observed.
D000818:Animals; D000941:Antigens / Q000009:adverse effects*; D019393:Arrestin; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D012173:Retinitis / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*; D014605:Uveitis / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*
D000941:Antigens; D019393:Arrestin