Underlying mechanisms of the effects of spinal cord stimulation in motor disorders. A review of the discussion.
Possible underlying neurophysiological mechanisms of spinal cord stimulation in the modification of motor disorders were discussed by scientists working in research on motor control mechanisms. Changes of motor unit properties in upper motoneuron lesions were reviewed, the role of proprioceptive input and long-loop reflexes in motor control was discussed, analysis of ramp and ballistic movements in motor control was presented, and some aspects of neural control of locomotion were reviewed. Some physiological considerations of the influence of electrical stimulation on various neural functions were given and the conclusion was reached that, at present, no definitive models of the action of spinal cord stimulation are available.
D000818:Animals; D002415:Cats; D002490:Central Nervous System / Q000502:physiology; D004599:Electric Stimulation Therapy; D006801:Humans; D009068:Movement; D009069:Movement Disorders / Q000628:therapy*; D009132:Muscles / Q000502:physiology; D013116:Spinal Cord