[Variation in cellular immunity - its bearings on effectiveness of steroids used during labour (author's transl)].
Thirty-five mothers and their newborns were examined for immunosuppressive effects of dexamethasone administered during labour (0.5 mg/kg body weight). Decline of both active and total t-cells was recorded from the mothers (p < 0.5; p < 0.01). No deviation was recordable from b-cells. The ratio of t-cells, b-cells, and O-cells in premature and full-term newborns was reduced to something below the values obtained from control groups. The difference, however, was not significant.
D001402:B-Lymphocytes / Q000276:immunology*; D003907:Dexamethasone / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007231:Infant, Newborn; D007958:Leukocyte Count; D008231:Lymphopenia / Q000139:chemically induced; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control; D013601:T-Lymphocytes / Q000276:immunology*
D003907:Dexamethasone
Veränderung der zellulären Immunität auf die Wirkung der während der Geburt verwendeten Steroide.