title: [Effect of antiserum against isologous aggregated immunoglobulins on synthesis of nonspecific immunoglobulins in mice immunized with sheep erythrocytes].
abstract: Injection of antiserum against isologous aggregated immunoglobulins into mice immunized with sheep red blood cells (5X10(7)) suppressed by 20% on the average the synthesis of nonspecific immunoglobulins. Concurrently the antiserum caused a 70% decrease in the amount of rosette-forming cells, but did not affect the proliferation of anti-body-forming cells and hemagglutinin production. The data obtained warrant an assumption that the part of B lymphocytes bearing aggregated antibodies are responsible for the synthesis of nonspecific immunoglobulins.
mesh_terms: D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology; D006388:Hemagglutinins / Q000096:biosynthesis; D007106:Immune Sera / Q000494:pharmacology*; D007136:Immunoglobulins / Q000096:biosynthesis* / Q000276:immunology; D051379:Mice; D008808:Mice, Inbred CBA; D012397:Rosette Formation; D012756:Sheep / Q000276:immunology; D013154:Spleen / Q000276:immunology
chemical_list: D006388:Hemagglutinins; D007106:Immune Sera; D007136:Immunoglobulins
vernacular_title: Vliianie antisyvorotki protiv izologichnykh agregirovannykh immunoglobulinov na sintez nespetsificheskikh immunoglobulinov u mysheĭ, immunizirovannykh éritrotsitami barana.