title: Acute toxicities of toxaphene and endrin to larvae of seven species of amphibians.
abstract: Seven species of amphibian larvae were exposed to toxaphene and endrin in a continuous-flow dosing system to determine differences in sensitivity to the two compounds, EC50 and LC50 estimates varied from those for Rana sphenocephala by no more than one order of magnitude when calculated on the basis of intended concentrations. Removal of pesticides from water by the test animals was significant and it makes interpretation of results difficult. Continuous-flow toxicity tests conflict with the adaptations of amphibian larvae for static water; use of such tests for amphibians requires further evaluation.
mesh_terms: D000557:Ambystoma / Q000502:physiology; D000663:Amphibians / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002025:Bufonidae / Q000502:physiology; D004732:Endrin / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D007814:Larva; D007928:Lethal Dose 50; D011892:Rana catesbeiana / Q000502:physiology; D011898:Ranidae / Q000502:physiology; D013045:Species Specificity; D014112:Toxaphene / Q000633:toxicity*
chemical_list: D007306:Insecticides; D014112:Toxaphene; D004732:Endrin