title: Presence of one essential arginine that specifically binds the 2'-phosphate of NADPH on each of the ketoacyl reductase and enoyl reductase active sites of fatty acid synthetase.
mesh_terms: D064431:3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; D000213:Acyl Carrier Protein / Q000378:metabolism; D000227:Adenine Nucleotides / Q000494:pharmacology; D000429:Alcohol Oxidoreductases / Q000378:metabolism; D001120:Arginine / Q000378:metabolism*; D001665:Binding Sites; D003931:Diacetyl / Q000494:pharmacology; D044943:Fatty Acid Desaturases / Q000378:metabolism; D064429:Fatty Acid Synthases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007651:Keto Acids; D046911:Macromolecular Substances; D009249:NADP / Q000378:metabolism*; D010658:Phenylglyoxal / Q000494:pharmacology
chemical_list: D000213:Acyl Carrier Protein; D000227:Adenine Nucleotides; D007651:Keto Acids; D046911:Macromolecular Substances; D009249:NADP; D001120:Arginine; D000429:Alcohol Oxidoreductases; D064431:3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; D044943:Fatty Acid Desaturases; D064429:Fatty Acid Synthases; D003931:Diacetyl; D010658:Phenylglyoxal