Simultaneous recovery of beta-lactamase-negative and beta-lactamase-positive Haemophilus influenzae type b from cerebrospinal fluid of a neonate.
A case of Haemophilus influenzae type b meningitis in a neonate from whom both a beta-lactamase-negative and a beta-lactamase-positive strain were isolated simultaneously is reported. Both bacteriology laboratory technicians and clinicians should be aware of this phenomenon when performing sensitivity tests on H influenzae isolates or treating patients with serious H influenzae infection.
D002701:Chloramphenicol / Q000627:therapeutic use; D006193:Haemophilus influenzae / Q000201:enzymology / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000134:cerebrospinal fluid* / Q000188:drug therapy; D008297:Male; D008583:Meningitis, Haemophilus / Q000134:cerebrospinal fluid* / Q000188:drug therapy; D001618:beta-Lactamases / Q000378:metabolism
D002701:Chloramphenicol; D001618:beta-Lactamases