title: Experimental ectopic mineralization in young boars I. The role of supplemental vitamin D inthe etiology.
abstract: Young boars supplemented orally with 800, 500,300 and 100 IU of vitamin D2/kg of feed and control boars not supplemented with vitamin D2 for four months developed mineralization in the left atrial endocardium, lamina muscularis mucosae of the fundic stomach and other sites. Since low levels of supplementation with vitamin D2 did not eliminate the lesions, the levels of vitamin D2 added appeared not to be involved in the pathogenesis. All boars had mild hypercalcemia throughout the experiment, and phosphorus levels in sera were lower in all animals receiving than in those not receiving calciferol. Mild morphological lesions of rickets developed in several boars not receiving supplemental vitamin D2 and in boars supplemented with 100 an 300 IU/kg of feed.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002114:Calcinosis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D004872:Ergocalciferols / Q000008:administration & dosage*; D008297:Male; D009206:Myocardium / Q000473:pathology; D012272:Ribs / Q000473:pathology; D012279:Rickets / Q000209:etiology / Q000473:pathology / Q000662:veterinary; D013270:Stomach / Q000473:pathology; D013552:Swine; D013553:Swine Diseases / Q000209:etiology* / Q000473:pathology
chemical_list: D004872:Ergocalciferols