Analysis of differentiated T-cell subpopulations: difference in radiosensitivity of immune responses to allogeneic antigen.
The radiosensitivity of immune responses to allogeneic tumor cells was compared. Delayed hypersensitivity as demonstrated by macrophage migration inhibition and antibody production as detected by immune adherence test were extremely radiosensitive. The radiosensitive nature of macrophage migration inhibition was in marked contrast to he radioresistance of the delayed footpad reaction. The generation of cytotoxicity was relatively radioresistant.
D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects; D000951:Antigens, Neoplasm / Q000276:immunology; D002464:Cell Migration Inhibition; D003602:Cytotoxicity, Immunologic / Q000528:radiation effects; D005260:Female; D006968:Hypersensitivity, Delayed; D007104:Immune Adherence Reaction; D008264:Macrophages / Q000276:immunology / Q000528:radiation effects; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000276:immunology* / Q000528:radiation effects
D000951:Antigens, Neoplasm