Establishment of a B-compatible chicken line with normogammaglobulinaemia and dysgammaglobulinaemia (IgM/IgG).
A dysgammaglobulinaemic line of chickens homozygous at the major histocompatibility complex has been established. In these chickens the IgG levels are decreased 10 to 100 times and IgM levels are increased 2 to 10 times when compared to those of normal birds. Dysgammaglobulinaemia is genetically determined. No linkage with the major histocompatibility complex of the chicken has been found.
D000017:ABO Blood-Group System / Q000276:immunology*; D000818:Animals; D001947:Breeding; D002645:Chickens / Q000235:genetics; D004406:Dysgammaglobulinemia / Q000235:genetics / Q000662:veterinary*; D005260:Female; D017099:IgG Deficiency; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis*; D008297:Male; D011201:Poultry Diseases / Q000235:genetics*; D016038:Skin Transplantation; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
D000017:ABO Blood-Group System; D007074:Immunoglobulin G; D007075:Immunoglobulin M