Comparison of the pregnancy-associated murine protein-2 and human pregnancy-specific beta 1-glycoprotein.
Immunological cross-reaction between human pregnancy-specific beta 1-glycoprotein (SP-1) and pregnancy-associated murine protein-2 (alpha 2-PAMP, PAMP-2) was demonstrated by line immunoelectrophoresis using antibodies against the proteins raised in hens. The pattern of change of PAMP-2 and SP-1 values in serum during pregnancy was very similar. The murine placental growth-rate corresponded to PAMP-2 levels in maternal serum during pregnancy, indicating placental origin. We suggest that the mouse and its PAMP-2 can be used to study human SP-1.
D000818:Animals; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D051379:Mice; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000097:blood*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000097:blood*
D011257:Pregnancy Proteins; D011268:Pregnancy-Specific beta 1-Glycoproteins