title: T lymphocyte mobility: defects and effects of ascorbic acid, histamine and complexed IgG.
abstract: T lymphocyte mobility is low in patients with low neutrophil mobility. Thymocytes move comparably with normal mature T lymphocytes. Histamine accelerates T lymphocyte mobility in healthy subjects, patients with defective lymphocyte mobility and thymocytes. Ascorbic acid increases lymphocyte mobility of healthy subjects and thymocytes. Inhibition of mobility of T- or Tmu-depleted T lymphocytes by complexed IgG casts doubt on previous reports that the T gamma cells do not move.
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000276:immunology*; D001205:Ascorbic Acid / Q000494:pharmacology*; D002465:Cell Movement / Q000187:drug effects; D002648:Child; D006402:Hematologic Diseases / Q000276:immunology; D006632:Histamine / Q000494:pharmacology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D006632:Histamine; D001205:Ascorbic Acid