[Content of T- and B-lymphocytes in the blood of patients with polar types of leprosy].
The content of T and B lymphocytes in the peripheral blood of patients with polar types of leprosy and healthy adults was determined. The lepromatous (severe) form of leprosy was found to be accompanied by a sharp decrease in the percentage of T lymphocytes, while the percentage of B lymphocytes perceptibly increased. In patients with the tuberculoid type of leprosy only an insignificant decrease in the percentage of T lymphocytes was observed, while the level of B lymphocytes remained normal. These data indicate that in the severe form of leprosy cellular immunity is deeply suppressed, and the nonspecific stimulation of humoral immunity occurs.
D001402:B-Lymphocytes; D006801:Humans; D007918:Leprosy / Q000097:blood*; D007958:Leukocyte Count; D013601:T-Lymphocytes
Soderzhanie T- i B-limfotsitov krovi u bol'nykh poliarnymi tipami lepry.