title: Serotype and ampicillin susceptibility of Haemophilus influenzae causing systemic infections in children: 3 years of experience.
abstract: Over a 3-year period, 96% of systemic infections in children caused by Haemophilus influenzae were of serotype b. Of 346 invasive infections, 15 (4%) were caused by non-type b H. influenzae. The monthly prevalence of ampicillin resistance in all isolates was highly variable (0 to 63%). Ampicillin resistance in H. influenzae causing invasive disease occurred in 13% of non-type b and 21.8% of type b isolates. There was no significant difference (x2 - 0.21; p greater than 0.10) in the rate of ampicillin resistance between type b and non-type b H. influenzae causing systemic illness in children over a 3-year period.
mesh_terms: D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification* / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000382:microbiology*; D008297:Male; D010403:Penicillin Resistance; D018805:Sepsis / Q000382:microbiology; D012703:Serotyping
chemical_list: D000667:Ampicillin