[Cellular sensitization against gluten in coeliac disease (author's transl)].
The leucocyte-adherence inhibition test was used on 24 patients with malabsorption syndrome, results being compared with those from patients with enteritis of other causes, and those with normal gastro-intestinal tract in order to test cellular gluten sensitization. The test makes it possible to distinguish between gluten-induced and non-gluten induced enteritis. There was a significant linear correlation to inflammatory activity as determined by biopsy as well as reduction in villous length and the villi-crypt index. The results suggest a primary T-cell dependent gluten (or gliadin) sensitization in the aetiology of coeliac disease.
D000293:Adolescent; D000328:Adult; D002446:Celiac Disease / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004751:Enteritis / Q000276:immunology; D005260:Female; D005983:Glutens; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D007957:Leukocyte Adherence Inhibition Test; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes
D005983:Glutens
Zelluläre Sensibilisierung gegen Gluten bei der Coeliakie. Nachweis mittels des Leukozyten-Adhärenz-Inhibitionstests.