Immune complexes in acute pancreatitis.
Immune complexes were detected in the sera of ten of 22 patients with acute pancreatitis using a Clq deviation assay. Five of these were positive using a second technique. There was no correlation between immune complexes and clinical or aetiological features of the pancreatitis. Two patients with immune complexes developed a benign and transient pancreatic polyarthritis. Immune complexes may provide one common path in the sequence of pathogenic events that lead to pancreatitis.
D000208:Acute Disease; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001168:Arthritis / Q000209:etiology / Q000276:immunology; D003166:Complement Activating Enzymes / Q000032:analysis; D015922:Complement C1q; D005260:Female; D006323:Heart Arrest / Q000209:etiology / Q000276:immunology; D006386:Hemagglutination Tests; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000276:immunology*; D011863:Radioimmunoassay; D012217:Rheumatoid Factor / Q000032:analysis
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D015922:Complement C1q; D012217:Rheumatoid Factor; D003166:Complement Activating Enzymes