[Evaluation of T-lymphocytic activity tested by E rosettes test for rheumatoid arthritis (author's transl)].
In a group of 25 patients with rheumatoid arthritis, the percent of erythrocyte rosettes forming cells (ERFC) was found significantly decreased in patients with rheumatoid factor positive (RF+), whereas ERFC were normal in the RF negative patients (RF--). Likely, T-lymphocytic depression in the RF+ patients could be related to a T-suppressor lymphocytes deficit and therefore, B-lymphocytes would be abnormally stimulated. Moreover, in the RF-- patients, B-lymphocytes would not be enhanced for the normal T-suppressor lymphocytes activity.
D001172:Arthritis, Rheumatoid / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007104:Immune Adherence Reaction; D007958:Leukocyte Count; D012217:Rheumatoid Factor / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
D012217:Rheumatoid Factor
Valutazione dell'attività T-linfocitaria esaminata con il test delle rosette "E" nell'artrite reumatoide.