[Histochemical studies of the immunomorphological state of the regional lymph nodes in stomach cancer].
Histochemically (including the determination of RNA, acid and alkaline phosphatase, 5-nucleotidase and ATP-ase) the kinetics of the T-and B-cell region representation in regional lymph nodes has been studied in 54 gastric cancer patients. Four types of regional immune reactions were distinguished with regard to which the frequency of regional metastases and the survival rate in 30 patients were followed up. Metastatic involvement of the lymph nodes with morphohistochemical signs typical for the first type of immune response was found to occur in 2 of 14 cases, in 12 of 20 cases according to the second and in 4 of 16 cases according to the third one. If the group comprising 8 patients with activization of the regional immune protection according to the cell type showed an average survival of 8.7 months, in 22 patients with a predominance of the 2-4 types of regional immune reactions a shorter survival was noted, on average 5.1, 4.3 and 0.7 months correspondingly.
D001402:B-Lymphocytes / Q000276:immunology; D006651:Histocytochemistry; D006801:Humans; D007111:Immunity, Cellular; D008198:Lymph Nodes / Q000276:immunology / Q000378:metabolism*; D008207:Lymphatic Metastasis; D013274:Stomach Neoplasms / Q000276:immunology / Q000378:metabolism*; D013601:T-Lymphocytes / Q000276:immunology
Gistokhimicheskie issledovaniia immunomorfologicheskogo sostoianiia regionarnykh limfouzlov pri rake zheludka.