Radiotherapy changes of the pediatric hip.
Significant radiation-induced abnormalities (aseptic necrosis of the femoral heads, slipped capital femoral epiphysis, radiation-induced sarcoma) were identified in eight of 44 patients aged 16 years or younger at the time of radiotherapy and followed for at least 3 years. The incidence is 18% in the entire group and 25% (8/32) if only patients with radiographs of the hips 3 or more years after therapy are considered. The first evidence of abnormality developed 13 years after irradiation in one patient. The need for long term follow-up of therapeutically irradiated children is stressed.
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004839:Epiphyses, Slipped / Q000209:etiology*; D005270:Femur Head; D005271:Femur Head Necrosis / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D009369:Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors