[Effect of hydrocortisone on the development of experimental atherosclerosis in rabbits].
The role of the immunocompetent system in the development of experimental atherosclerosis was studied in experiments with 51 rabbits given hydrocortisone injections. Hydrocortisone produced atrophy of T and B systems of the lymph nodes and spleen. Under these conditions the experimental sclerosis developed little regardless high lipid blood level. This circumstance provides one more argument of the role played by the immunologic factors in the formation and development of atherosclerosis.
D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D001323:Autoantibodies / Q000032:analysis; D001402:B-Lymphocytes / Q000166:cytology; D002452:Cell Count; D003094:Collagen / Q000276:immunology; D004549:Elastin / Q000276:immunology; D006854:Hydrocortisone / Q000627:therapeutic use*; D007165:Immunosuppression Therapy; D008198:Lymph Nodes / Q000166:cytology; D010950:Plasma Cells / Q000166:cytology; D011817:Rabbits; D013601:T-Lymphocytes / Q000166:cytology
D001323:Autoantibodies; D003094:Collagen; D004549:Elastin; D006854:Hydrocortisone
Vliianie gidrokortizona na razvitie éksperimental'nogo ateroskleroza u krolikov.