[Juvenile rheumatoid arthritis and HLA-B27].
Forty children with juvenile rheumatoid arthritis were studied to determine the frequency of the histocompatibility antigen HLA [human leukocyte antigen)-B27 in this disease and to characterize the arthropathy associated with this antigen. HLA-B27 was detected in four patients (10%). Its presence was associated in a statistically significant manner with sacroiliitis demonstrated radiologically and with a greater age at the time symptoms in the joints first appeared; this age was, on average, 10 years, compared with 6.29 years for the children without HLA-B27.
D000293:Adolescent; D000974:Antibodies, Antinuclear; D001171:Arthritis, Juvenile / Q000150:complications / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006680:HLA Antigens / Q000302:isolation & purification*; D015796:HLA-B27 Antigen; D006801:Humans; D007223:Infant; D008297:Male
D000974:Antibodies, Antinuclear; D006680:HLA Antigens; D015796:HLA-B27 Antigen
Arthrite rhumatoïde juvénile et HLA-B27.