title: The specificity of dehydrogenases.
abstract: The specificity of dehydrogenases for coenzyme (and coenzyme analogues), and substrate (and substrate analogues) is discussed in relation to structure, function, and evolution. Examples concern compounds that have very different structures, reactions that play widely differing roles in the life of the organism, and organisms of greatly differing types. The examples illustrate general points of interest and importance.
mesh_terms: D000429:Alcohol Oxidoreductases / Q000378:metabolism; D000445:Aldehyde Oxidoreductases / Q000378:metabolism; D000818:Animals; D006736:Horses; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D009243:NAD; D009249:NADP; D010088:Oxidoreductases / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
chemical_list: D009243:NAD; D009249:NADP; D010088:Oxidoreductases; D000429:Alcohol Oxidoreductases; D007770:L-Lactate Dehydrogenase; D000445:Aldehyde Oxidoreductases