The effect of renal transplantation on basal serum gastrin concentration.
Basal serum gastrin concentration was measured before and every week during the initial 5 weeks after renal transplantation in 9 of 20 patients with chronic renal failure who obtained a well functioning renal transplant. Furthermore, calcium and phosphorus metabolism in relation to serum gastrin was investigated in all 20 patients 5 weeks after transplantation. Before renal transplantation, serum gastrin was markedly elevated as compared with the levels in normal controls. During the first 3-5 weeks after renal transplantation, serum gastrin decreased towards normal values. A slight but significant increase in serum gastrin persisted 5 weeks after transplantation. No significant relation between changes in serum gastrin concentration and in calcium and phosphorus metabolism was observed.
D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000378:metabolism; D003404:Creatinine / Q000097:blood; D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism; D014184:Transplantation, Homologous
D005755:Gastrins; D010758:Phosphorus; D003404:Creatinine; D002118:Calcium