Myopathy due to epsilon amino-caproic acid.
A subacute necrotizing myopathy developed in a patient treated with epsilon amino-caproic acid (EACA) for subarachnoid hemorrhage. The muscle biopsy showed features suggesting that the muscle fiber necrosis might have been due to capillary damage. An attempt to induce EACA myopathy in the rat was made, but no abnormality developed.
D000208:Acute Disease; D000328:Adult; D000614:Aminocaproates / Q000009:adverse effects*; D015119:Aminocaproic Acid / Q000009:adverse effects*; D000818:Animals; D001706:Biopsy; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D009132:Muscles / Q000276:immunology / Q000473:pathology; D009135:Muscular Diseases / Q000097:blood / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology; D009336:Necrosis; D051381:Rats
D000614:Aminocaproates; D015119:Aminocaproic Acid