title: Ro 13-9904/001, a novel potent and long-acting parenteral cephalosporin.
abstract: Ro 13-9904/001 is a novel parenteral cephalosporin antibiotic with potent in vitro activity against a wide range of beta-lactamase-producing and non-producing pathogens. In addition, Ro 13-9904/001 proved to possess a very long plasma half-life and, as a consequence, high prophylactic in vivo effectiveness.
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects / Q000201:enzymology; D002443:Ceftriaxone; D002510:Cephalosporinase / Q000378:metabolism; D002511:Cephalosporins / Q000097:blood / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006207:Half-Life; D007700:Kinetics; D051379:Mice; D051381:Rats
chemical_list: D002511:Cephalosporins; D002443:Ceftriaxone; D002510:Cephalosporinase