[Cytogenetics of preleukemic states].
In about a half of preleukemic states it is possible to find chromosomal aberrations, as three n. degrees 8 chromosomes, a single n. degrees 7 or n. degrees 5 chromosome, or a partial deletion of long arm or n. degrees 5 chromosomes. From a prognostic point of view, the presence of the indicated chromosomal abnormalities show a three times increased risk to suffer leukemia. Several abnormal cell clones may be produced, but generally only one of them has the proliferative capacity to establish an evolutive non-lymphoblastic acute leukemic process.
D000208:Acute Disease; D000741:Anemia, Aplastic / Q000235:genetics; D002869:Chromosome Aberrations; D002877:Chromosomes, Human / Q000648:ultrastructure; D002999:Clone Cells / Q000648:ultrastructure; D006801:Humans; D007938:Leukemia / Q000235:genetics; D007951:Leukemia, Myeloid / Q000235:genetics; D011289:Preleukemia / Q000145:classification / Q000235:genetics*; D011379:Prognosis
Citogenética de los estados preleucémicos.