title: [Seronegative, HLA B 27-associated spondylarthritis. - New orientation in nomenclature and classification?].
abstract: It is shown that the concept of "seronegative HLA B 27 associated spondarthritis," which is unsatisfactory even as a name, cannot be accepted as a new overgroup in a logically constructed classification. HLA B 27 occurs in certain of these illnesses almost inevitably as a predisposing antigen; in others it is merely a factor modifying the pattern of disease. The illnesses thus are obviously different. In any case, the concept itself is not a diagnosis, in spite of the fact that it is at present often employed as a diagnostic term.
mesh_terms: D001168:Arthritis / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D015796:HLA-B27 Antigen; D006801:Humans; D013122:Spinal Diseases / Q000276:immunology; D013167:Spondylitis, Ankylosing / Q000145:classification* / Q000276:immunology; D009626:Terminology as Topic
chemical_list: D006680:HLA Antigens; D015796:HLA-B27 Antigen
vernacular_title: Seronegative, HLA B 27-assoziierte Spondarthritiden. - Neuorientierung in Nomenklatur und Klassifikation?