Influence of thymic factor X-5 (TFX-5) "Polfa" on mitogenic response of murine thymocytes to concanavalin A.
The influence of thymic factor X (TFX-5 "Polfa") on mitogenic response of different subpopulations of murine thymocytes has been studied. Data are presented which indicate that proliferative response to concanavalin A of cortical ("immature") thymocytes is enhanced in the presence of TFX-5 whereas the response of medullary ("mature") thymocytes is inhibited.
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D008213:Lymphocyte Activation; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*
D003208:Concanavalin A