Hemodynamic effects of an intravenous injection of mexiletine in patients hospitalised in intensive care units.
Hemodynamic effects of mexiletine were studied in 15 patients with normal sinus rhythm; most of them had a myocardial infarction. Except for a slight increase in peripheral vascular resistance, no other significant change in hemodynamic parameters was found after an intravenous injection of 1.5 mg/kg of mexiletine at 25 mg/min.
D000328:Adult; D000368:Aged; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D007362:Intensive Care Units; D008297:Male; D008801:Mexiletine / Q000008:administration & dosage / Q000494:pharmacology*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D011437:Propylamines / Q000494:pharmacology*; D013997:Time Factors
D011437:Propylamines; D008801:Mexiletine