[Evaluation of some nonspecific immunological parameters in patients with oral cavity carcinoma undergoing cryosurgery].
The authors have evaluated general immunocompetence of 10 pts. after a cryosurgery treatment for oral squamous cell carcinoma. Serum immunoglobulin levels, C3 - C4, peripheral lymphocytes, E-rosette forming cells, lymphocyte response to PHA were analized before and after 7 and 14 days a single cryotreatment. Humoral immunity was scarcely modified by the cryosurgery; on the contrary a statistically significant augment of peripheral large lymphocytes (p < 0,0001), T-lymphocytes (p < 0,025) and lymphocyte response to PHA (p < 0,001) was found both after 7 and 14 days.
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000601:surgery; D003176:Complement C3 / Q000276:immunology; D003181:Complement C4 / Q000276:immunology; D003452:Cryosurgery; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology* / Q000601:surgery; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins
Valutazioni di alcuni parametri immunologici aspecifici in pazienti con carcinoma del cavo orale sottoposti a criochirurgia.