title: A method for increasing the frequency response of voltage clamped myelinated nerve fibres.
abstract: In voltage clamp experiments on myelinated nerve fibres the time resolution of the current measurement is limited by the low-pass characteristics of the internodes. We increased the corner frequency of the current passing internode by grounding one half of this internode externally. Using a simplified equivalent circuit we calculated an increase in the bandwidth of the internode by a factor of about 6. Consequently, the peak value of the recorded capacity current increased while its duration was considerably shortened.
mesh_terms: D000818:Animals; D004553:Electric Conductivity; D004594:Electrophysiology; D008566:Membranes / Q000502:physiology; D008722:Methods; D009412:Nerve Fibers / Q000502:physiology; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D011893:Rana esculenta / Q000502:physiology