title: The effect of sulfide and cyanide on nerve function.
abstract: Sciatic nerve bundles from Rana pipiens were immersed in amphibian Ringer containing sulfide or cyanide. Subsequent examination of the compound action potential (CAP) revealed a distinct difference in the effects of these two anions. Whereas cyanide produced a nerve incapable of repeated firings, sulfide-treated nerves displayed an increased CAP which showed no tendency to diminish over extended stimulation periods.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D003486:Cyanides / Q000633:toxicity*; D005260:Female; D008297:Male; D009420:Nervous System / Q000187:drug effects*; D011894:Rana pipiens; D012584:Sciatic Nerve / Q000187:drug effects / Q000502:physiology; D013440:Sulfides / Q000633:toxicity*
chemical_list: D003486:Cyanides; D013440:Sulfides