title: [Synthesis and pharmacological activity of N-(dialkylaminoethyl)amides and dialkylaminoethyl esters of alpha-(arylamino)phenylacetic acids].
abstract: A series of N-(dialkylaminoethyl) amides and (dialkylaminoethyl) esters of alpha-(arylamino) phenylacetic acids were synthesized. For several amidic derivatives pharmacological screening showed appreciable analgesic antiinflammatory and sedative activity, whereas some esteric derivatives displayed significant antispasmodic activity.
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis*; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis; D051379:Mice; D010276:Parasympatholytics / Q000138:chemical synthesis; D010648:Phenylacetates / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D006993:Hypnotics and Sedatives; D010276:Parasympatholytics; D010648:Phenylacetates
vernacular_title: Sintesi ed attività farmacologica di N-(dialchilaminoetil)amidi e di dialchilaminoetilesteri di acidi alpha-(arilamino)fenilacetici.