Immunopotentiation of tumor-bearing and toxohormone treated mice by human ceruloplasmin.
Human ceruloplasmin was shown to have a restorative effect on the decrease of delayed hypersensitivity in sarcoma-180-bearing mice and of helper T-cell activity in cell-free. Ehrlich cancerous ascitic fluid-treated mice. Furthermore, it was also shown that ceruloplasmin augments the in vivo generation of alloreactive cytotoxic cell which consist of cytotoxic T-lymphocytes, cytotoxic macrophages and K cells.
D000276:Adjuvants, Immunologic; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology*; D002374:Catalase / Q000037:antagonists & inhibitors*; D002570:Ceruloplasmin / Q000494:pharmacology*; D004731:Endotoxins / Q000494:pharmacology*; D005260:Female; D006968:Hypersensitivity, Delayed; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology*; D051379:Mice; D008815:Mice, Inbred Strains; D009363:Neoplasm Proteins / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000276:immunology*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*
D000276:Adjuvants, Immunologic; D004731:Endotoxins; D009363:Neoplasm Proteins; C010355:toxohormone; D002374:Catalase; D002570:Ceruloplasmin