Lysosomal enzyme activities in a case of T-cell chronic lymphocytic leukaemia.
This study indicated that (i) high levels of N-acetyl-beta-glucosaminidase and beta-glucuronidase could be demonstrated cytochemically in T-CLL lymphocytes, and (ii), the biochemical activities of both enzymes were significantly increased in T-CLL lymphocytes compared with B-CLL lymphocytes. It would appear that the biochemical and cytochemical determination of these lysosomal enzyme activities offers an additional means of distinguishing T-CLL and B-CLL lymphocytes.
D000118:Acetylglucosaminidase / Q000032:analysis; D001402:B-Lymphocytes / Q000201:enzymology; D005966:Glucuronidase / Q000032:analysis; D006801:Humans; D007945:Leukemia, Lymphoid / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D008875:Middle Aged; D013601:T-Lymphocytes / Q000201:enzymology*
D005966:Glucuronidase; D000118:Acetylglucosaminidase