Circulating immune complexes detected by C1q solid phase assay in leprosy.
Sixty-three sera of patients with leprosy were tested for the presence of circulating immune complexes (CIC) by C1q solid phase assay (C1qSPA). The mean values in CIC levels in leprosy patients were very high in comparison to native and European controls. No difference was found in the tuberculoid and lepromatous forms, but there was a good correlation between the presence of CIC and autoantibodies.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis* / Q000276:immunology; D003166:Complement Activating Enzymes / Q000032:analysis; D015922:Complement C1q; D005260:Female; D006801:Humans; D007918:Leprosy / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000936:Antigen-Antibody Complex; D015922:Complement C1q; D003166:Complement Activating Enzymes