N,N-Dicyclohexylhexahydrodiazepines and N,N-dicyclohexylperhydrodiazocines as possible antiinflammatory agents.
Four 6,6-disubstituted 1,4-dicyclohexyl-5,7-diketohexahydro-7H-dro-7H-diazepines [1,4] (I a-d) and three 3,3-disubstituted 1,5-dicyclohexyl-2,4-diketoperhydrodiazocines [1,5] (II a-c) were prepared and their structure and pharmacological activity were investigated.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis; D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology; D001392:Azocines / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D051381:Rats
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001381:Azepines; D001392:Azocines