Metal allergy and the surgical patient.
Allergy to metal implants is under study at the Dartmouth-Hitchcock Medical Center using in vitro examination of white blood cell migration. Retrospective data from 121 patients confirm that allergic responses do occur. Prospective data are being gathered to investigate the incidence, prevalence and relation to morbidity.
D000293:Adolescent; D000328:Adult; D001858:Bone Nails / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000150:complications; D004864:Equipment and Supplies; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology / Q000276:immunology*; D066298:In Vitro Techniques; D007961:Leukocyte Migration-Inhibitory Factors / Q000032:analysis*; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology; D008222:Lymphokines / Q000032:analysis*; D008297:Male; D008670:Metals / Q000009:adverse effects*; D008875:Middle Aged; D010835:Phytohemagglutinins / Q000494:pharmacology; D013514:Surgical Procedures, Operative
D007961:Leukocyte Migration-Inhibitory Factors; D008222:Lymphokines; D008670:Metals; D010835:Phytohemagglutinins