[Clinical studies of 9, 3"-diacetylmidecamycin (author's transl)].
1. We had a chance to administer the "MOM dry syrup' (MOM fine granules) to 22 patients: 6 patients with streptococcal infections and 16 patients with other respiratory tract infections. The clinical efficacy was good in 16 cases and its rate was 80%. 2. The causative organisms were isolated from 9 cases: 6 cases with S. pyogenes, 2 with S. pneumoniae and 1 case with B. pertussis. All of the clinical isolates were eradicated except for the S. pyogenes strains. 3. Any remarked side effects were not observed but only eosinophilia in 2 cases. 4. Because of no bitterness of the MOM dry syrup, all the children take it easily. 5. MOM was effective in all the cases of pertussis and Mycoplasma pneumoniae pneumonia. As for streptococcal and pneumococcal infections, it is necessary to administer MOM under the control of bacterial sensitivity.
D000293:Adolescent; D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D007933:Leucomycins / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D015644:Miocamycin; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D013290:Streptococcal Infections / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D007933:Leucomycins; D015644:Miocamycin