Technical problems and advances in the cerebellar-stimulating systems used for reduction of spasticity and seizures.
A series of 300 patients were implanted for chronic cerebellar stimulation (CCS) from February 1974 to June 1980. The charge density was in the range of 0.7-1.6 microCi/cm2/phase. There is a very narrow range of stimulation in which CCS is effective. Increasing above the range, clinical benefits cease; at levels over 10 microCi/cm2/phase, damage to the underlying conducting elements occurs which renders the prosthesis ineffective. Periodic monitoring of the implanted equipment is mandatory for a successful clinical program. Scalp recordings and radiography have detected a 53% failure rate in the I-108 RF linked system. The failed receivers were replaced with more reliable I-110 receivers and later with a fully implantable pulse generator. No change has been detected in the electrode button-cortex interface when measuring the access resistance up to 5 years later.
D002531:Cerebellum / Q000502:physiology*; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D004594:Electrophysiology; D004827:Epilepsy / Q000628:therapy; D006801:Humans; D009128:Muscle Spasticity / Q000628:therapy*; D011846:Radio Waves; D012535:Scalp / Q000502:physiology; D012640:Seizures / Q000628:therapy*