title: A study of degeneration, scar formation and regeneration after section of the optic nerve in the frog, Rana pipiens.
abstract: Degeneration, scar formation and regeneration have been studied after section of the optic nerve in the frog. In the normal optic nerve two types of macroglial cell were identified: astrocytes and oligodendroglia. Degeneration after injury proceeded rapidly in comparison with mammals but did not lead to the production of a dense scar. Before much scarring had developed, regenerating axons penetrated the lesioned area.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002921:Cicatrix / Q000473:pathology; D003714:Denervation; D008854:Microscopy, Electron; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D009900:Optic Nerve / Q000473:pathology / Q000502:physiology* / Q000648:ultrastructure; D011894:Rana pipiens