[Etiological approach to the analysis of the action of antidepressants].
An approach has been used, which shows the necessity of separate evaluation of the recovering action of antidepressants on zoosocial and locomotor activity of mice. It was shown that iprazid and amphetamine exert an independent effect on motor and zoosocial activity suppressed by rausedyl. Melipramin activates for a short period of time the motor but does not recover the zoosocial activity. Fluoxetin increases the zoosocial activity but that does not cause stable activation of the motor activity.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D005473:Fluoxetine / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D007490:Iproniazid / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012110:Reserpine / Q000037:antagonists & inhibitors; D012919:Social Behavior / Q000187:drug effects
D000928:Antidepressive Agents; D005473:Fluoxetine; D012110:Reserpine; D000661:Amphetamine; D007490:Iproniazid; D007099:Imipramine
Etiologicheskiĭ podkhod k analizu deĭstviia antidepressantov.