title: Therapy in pulmonary histiocytosis X.
abstract: Clinical findings and course of the disease are described in six patients suffering from pulmonary histiocytosis X. Diagnosis was suspected when a reticulonodular pattern was detected by conventional X-ray or by computerized tomography of the lungs. Laboratory tests were altered nonspecifically, and lung function was impaired. Signs of the disease improved spontaneously in one patient and when cytostatics were given in two of five patients. To judge the course of the disease, repeated controls of lung function parameters - besides roentgenographic methods - were of particular value.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D014747:Vinblastine; D008727:Methotrexate