The influence of salivary glands extirpation and (or) thymectomy on some physiological and immunological parameters in rats.
Spleen weight, blood counts and anti-SRBC response were estimated in rats subjected to thymectomy and (or) salivary gland extirpation. A significant decrease of spleen weight and number of circulating lymphocytes was observed after thymectomy or salivary glands extirpation. The number of PFC after immunization with SRBC was decreased after thymectomy but not after salivary glands extirpation or, surprisingly, after combined surgery.
D000818:Animals; D000921:Antibody-Producing Cells / Q000473:pathology; D001835:Body Weight; D007958:Leukocyte Count; D007964:Leukocytosis / Q000209:etiology; D008231:Lymphopenia / Q000209:etiology; D009929:Organ Size; D051381:Rats; D013154:Spleen / Q000473:pathology; D013361:Sublingual Gland / Q000601:surgery*; D013363:Submandibular Gland / Q000601:surgery*; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000601:surgery*