2'-Deoxyadenosine functionally uncouples adenylate cyclase from the guanyl nucleotide subunit without altering simultaneous GppNHp occupancy.
D000241:Adenosine / Q000494:pharmacology; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002110:Caffeine / Q000494:pharmacology; D002460:Cell Line; D002462:Cell Membrane / Q000201:enzymology; D003839:Deoxyadenosines / Q000494:pharmacology*; D004789:Enzyme Activation; D005910:Glioma; D006160:Guanosine Triphosphate / Q000031:analogs & derivatives*; D006165:Guanylyl Imidodiphosphate / Q000494:pharmacology*; D006822:Hybrid Cells / Q000201:enzymology; D007700:Kinetics; D046911:Macromolecular Substances; D051379:Mice; D009447:Neuroblastoma
D003839:Deoxyadenosines; D046911:Macromolecular Substances; D006165:Guanylyl Imidodiphosphate; D002110:Caffeine; D006160:Guanosine Triphosphate; D000262:Adenylyl Cyclases; D000241:Adenosine