title: Induction of heteroploidy in Gallus domesticus.
abstract: Intraperitoneal colcemid injection at the dose level of 0.37 mg/kg applied 3-4 h before the first oviposition produces a high frequency of triploids among the second oviposition eggs laid the first day after colcemid treatment. The triploids, mostly 3A-ZZW type, appear to be as developmentally compatible as contemporary diploids at both embryonic and hatching level. No other kinds of heteroploids besides triploids were found at hatching time even though a high frequency was observed in 24-h embryos.
mesh_terms: D000782:Aneuploidy; D000818:Animals; D002645:Chickens / Q000235:genetics*; D002875:Chromosomes / Q000187:drug effects*; D003703:Demecolcine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005821:Genetic Techniques; D007621:Karyotyping
chemical_list: D003703:Demecolcine