A case of cicatricial pemphigoid or cicatricial linear IgA bullous dermatosis.
A case has been described with clinical features of cicatricial pemphigoid, but immunofluorescent (IF) biopsy findings are suggestive of linear IgA bullous dermatosis (LABD), i.e., the presence of IgA deposits with a linear pattern at the basement membrane zone. The patient failed to respond to sulfones and gave a limited response to corticosteroid. These findings suggest that therapy of the type found to be effective in cutaneous forms of LABD, i.e., combinations of low doses of sulfones and corticosteroids, may be indicated in such cases.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001485:Basement Membrane / Q000276:immunology; D002921:Cicatrix / Q000209:etiology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D012867:Skin / Q000276:immunology; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000276:immunology*; D013427:Sulfapyridine / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D007070:Immunoglobulin A; D013427:Sulfapyridine