Hemodynamic effects of parenteral and oral mexiletine.
Intravenous mexiletine (250 mg in 10 min) given to patients at the acute stage of a myocardial infarction was responsible of a mild decrease of the left ventricular function; two of our patients presented bradycardia with hypotension, immediately corrected by atropine (i.v.). Adverse hemodynamic effects are seldom reported after oral administration.
D000284:Administration, Oral; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007275:Injections, Intravenous; D008801:Mexiletine / Q000008:administration & dosage / Q000494:pharmacology*; D011437:Propylamines / Q000494:pharmacology*; D013997:Time Factors
D011437:Propylamines; D008801:Mexiletine