Prostacyclin synthesis in human lymphatics.
The ability of human lymphatics to generate prostacyclin in important amounts (4.5 +/- 2.1 pg/mg/min) is described. The prostacyclin produced, exhibits the same properties as reported for arterial and venous tissue. No age and sex difference could be observed. The role of prostacyclin in physiology of lymphatics, however, is unknown.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000804:Angiotensin II / Q000494:pharmacology; D001792:Blood Platelets; D011464:Epoprostenol / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000494:pharmacology; D008208:Lymphatic System / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011453:Prostaglandins / Q000096:biosynthesis*; D012737:Sex Factors
D011453:Prostaglandins; D000804:Angiotensin II; D007660:Ketoprofen; D011464:Epoprostenol