Isolation of an ampicillin-resistant, non-beta-lactamase-producing strain of Haemophilus influenzae.
A 79-year-old female developed endocarditis and meningitis due to an ampicillin-resistant, non-beta-lactamase-producing strain of Haemophilus influenzae. Carbenicillin and gentamicin therapy resulted in bacteriological and clinical cure. The mechanism of resistance of ampicillin-resistant, non-beta-lactamase-producing strains of H. influenzae is unknown.
D000368:Aged; D000667:Ampicillin / Q000494:pharmacology*; D002701:Chloramphenicol / Q000627:therapeutic use; D005260:Female; D006192:Haemophilus Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D001618:beta-Lactamases / Q000032:analysis*
D002701:Chloramphenicol; D000667:Ampicillin; D001618:beta-Lactamases