title: [Changes in the T- and B-lymphocyte ratio in bone sarcoma patients before and after carminomycin treatment].
abstract: The clinical ratio of T- and B-lymphocytes in the peripheral blood of patients with osteogenic sarcoma and Ewing's sarcoma was studied. Significant changes in the ratio of T- and B-cells was found in the patients in the stage of generalization with metastases to the bones and lungs. During the treatment with carminomycin the relative number of T-cells reached the values close to the normal. The total number of lymphocytes in the blood and the absolute content of T- and B-cells in some patients remained decreased for a long period of time.
mesh_terms: D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects*; D001859:Bone Neoplasms / Q000188:drug therapy*; D002360:Carubicin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003630:Daunorubicin / Q000031:analogs & derivatives*; D006801:Humans; D007958:Leukocyte Count; D012516:Osteosarcoma / Q000188:drug therapy*; D012397:Rosette Formation; D012512:Sarcoma, Ewing / Q000188:drug therapy*; D013601:T-Lymphocytes / Q000187:drug effects*; D013997:Time Factors
chemical_list: D002360:Carubicin; D003630:Daunorubicin
vernacular_title: Izmenneiiia v sootnoshenii T- i B-limfotsikov u bol'nykh sarkomami kosteĭ do i posle lecheniia karminomitsinom.