title: Sequence homology and structural comparison between the chromosomal human alpha 1-antitrypsin and chicken ovalbumin genes.
abstract: The human chromosomal alpha 1-antitrypsin gene has been cloned. This gene is approximately 5 kilobase pairs long and contains three intervening sequences in the peptide-coding region. DNA sequences coding for the amino and carboxyl termini of a alpha 1-antitrypsin have been identified. Human alpha 1-antitrypsin and chicken ovalbumin show significant sequences homology and belong to a common protein super-family. Yet the number, position and size of intervening sequences reveal that the two genes are dissimilar.
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002645:Chickens; D003001:Cloning, Molecular; D005796:Genes; D010047:Ovalbumin / Q000235:genetics*; D000515:alpha 1-Antitrypsin / Q000235:genetics*
chemical_list: D000515:alpha 1-Antitrypsin; D010047:Ovalbumin