HL-A antigen frequency distribution in patients with gestational choriocarcinoma and their husbands.
HL-A (A,B,C, and DR) antigen frequency distribution was determined in 29 patients with choriocarcinoma and in their husbands, as well as in a matched control population of 21 healthy couples. All 29 patients had achieved complete sustained remission with chemotherapy. The HL-A antigen frequency distribution was normal in the choriocarcinoma patients and in their husbands and there was no abnormal HL-A antigen sharing between patients and their husbands. This study does not exclude the possibility that the pathogenesis of resistant choriocarcinoma may be dependent upon tumour-host histocompatibility.
D002822:Choriocarcinoma / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000276:immunology*; D014594:Uterine Neoplasms / Q000276:immunology*
D006680:HLA Antigens