title: Induced vestibular dysfunction in squirrel monkeys during rapid decompression.
abstract: The symptoms of postural instability and dizziness associated with decompression sickness could be ascribed to either damage of the vestibular apparatus or to central nervous system damage. However, a histological study of monkeys exposed to decompression reveals that these symptoms primarily result from damage to the vestibular apparatus (unless there are accompanying central deficits). Furthermore, the damage is of a type that causes new bone growth to occlude the otic fluid spaces of the semicircular canals. In some instances, there is sufficient bone growth to render the cristae ampullares as non-functional end organs. Such diminished vestibular function would present a serious threat to the diver.
mesh_terms: D000818:Animals; D003664:Decompression / Q000009:adverse effects*; D003665:Decompression Sickness / Q000503:physiopathology; D004242:Diving; D004584:Electronystagmography; D010498:Perilymph / Q000032:analysis; D012453:Saimiri; D012665:Semicircular Canals / Q000473:pathology / Q000502:physiology; D014724:Vestibular Function Tests; D014722:Vestibule, Labyrinth / Q000473:pathology / Q000503:physiopathology*