title: [Clinical features and treatment of Wegener's granulomatosis (author's transl)].
abstract: Between 1972 and 1978 a total of 16 patients, aged 19 to 70 years, seven of them women, were diagnosed as having Wegener's granulomatosis. The course of the disease in some instances was rapidly progressive, in some protracted. Nine patients have died, three of them within three months. The diagnosis can only be made after intensive ear-nose-throat, medical and histological studies. Early administration of cyclophosphamide seems to influence the course of the disease favourably.
mesh_terms: D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D003520:Cyclophosphamide
vernacular_title: Klinik und Therapie der Wegenerschen Granulomatose.