title: Pulmonary diffusing capacity of the bullfrog (Rana catesbeiana).
abstract: Carbon monoxide diffusing capacity of the lungs (DLCO) was measured in bullfrogs, Rana catesbeiana (mean body weight 260 g) along with oxygen uptake, pulmonary perfusion and lung volume. The measurements were all performed by methods depending on mass-spectrometry. Pulmonary oxygen uptake, DLCO and perfusion all increased with body temperature. At 20 degrees C O2-uptake was 0.49 ml STPD . kg-1 . min-1 at rest and DLCO was 0.022 ml STPD . kg-1 . min-1 . Torr-1. At 30 degrees C the values for O2-uptake and DLCO approximately doubled. Lung volume was large (90 ml . kg-1) and independent of body temperature. Oxygen uptake and DLCO of the bullfrog were small compared to values for a similar-sized mammal but the ratios of DLCO to O2-uptake quite similar. Analysis of available data on DLCO and O2-uptake in ectotherms also suggests a close correlation between O2-uptake and DLCO.
mesh_terms: D000818:Animals; D001831:Body Temperature; D002248:Carbon Monoxide; D008176:Lung Volume Measurements; D010101:Oxygen Consumption; D011653:Pulmonary Diffusing Capacity; D011892:Rana catesbeiana; D014692:Ventilation-Perfusion Ratio
chemical_list: D002248:Carbon Monoxide