Antimicrobial susceptibility of Staphylococcus saprophyticus and urethral staphylococci.
The activity of eight antimicrobial agents was determined against 115 isolates of Staphylococcus saprophyticus. All were susceptible to ampicillin, cephalexin, and trimethoprim-sulfamethoxazole and resistant to nalidixic acid and novobiocin. A bimodal pattern of susceptibility to erythromycin was observed: 80% were inhibited by 0.25 microgram/ml, whereas 13% required greater than or equal to 128 micrograms/ml. The following urethral staphylococci were susceptible to ampicillin, cephalexin, and nitrofurantoin but resistant to nalidixic acid: S. epidermidis, S. hominis, S. haemolyticus, S. warneri, S. simulans, and S. cohnii.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D006801:Humans; D008297:Male; D009582:Nitrofurantoin / Q000494:pharmacology; D009675:Novobiocin / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects*; D013420:Sulfamethoxazole / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014521:Urethra / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D009675:Novobiocin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D009582:Nitrofurantoin; D014295:Trimethoprim; D013420:Sulfamethoxazole