title: Creutzfeldt-Jakob disease in a 20-year-old woman.
abstract: A 20-year-old woman developed ataxia, extrapyramidal movements, myoclonus, and progressive dementia. Brain biopsy disclosed status spongiosus, diagnostic of Creutzfeldt-Jakob disease; this is the youngest spontaneous case ever reported. Creutzfeldt-Jakob disease can occur in young adulthood.
mesh_terms: D000328:Adult; D001284:Atrophy; D001706:Biopsy; D001921:Brain / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D009474:Neurons / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed; D014617:Vacuoles / Q000648:ultrastructure