The effect of sulfide and cyanide on nerve function.
Sciatic nerve bundles from Rana pipiens were immersed in amphibian Ringer containing sulfide or cyanide. Subsequent examination of the compound action potential (CAP) revealed a distinct difference in the effects of these two anions. Whereas cyanide produced a nerve incapable of repeated firings, sulfide-treated nerves displayed an increased CAP which showed no tendency to diminish over extended stimulation periods.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D003486:Cyanides / Q000633:toxicity*; D005260:Female; D008297:Male; D009420:Nervous System / Q000187:drug effects*; D011894:Rana pipiens; D012584:Sciatic Nerve / Q000187:drug effects / Q000502:physiology; D013440:Sulfides / Q000633:toxicity*
D003486:Cyanides; D013440:Sulfides