Anti-SS-A antibody and other antinuclear antibodies in systemic lupus erythematosus.
Randomly selected sera from 88 patients with systemic lupus erythematosus (SLE) were studied for the frequency of antibodies to SS-A, SS-B, RANA, RNP, Sm, Sc-1, and dsDNA. Results were in agreement with previous reports except for an increased incidence of anti-SS-A antibody (33%). Nine of 14 patients with anti-SS-A antibody on whom serial studies were performed had fluctuating titers. Titer changes often correlated with disease activity and dsDNA antibody levels.
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis*; D001324:Autoantigens / Q000032:analysis; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008297:Male; D009698:Nucleoproteins / Q000276:immunology*; D012217:Rheumatoid Factor / Q000032:analysis
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D001324:Autoantigens; D007136:Immunoglobulins; D009698:Nucleoproteins; D012217:Rheumatoid Factor