title: A case of cryoglobulinemic gangrene in myeloma with fatal outcome despite successful skin grafting.
abstract: Extensive necrosis of the skin, muscle and bone was produced after prolonged cooling in a case of myeloma with cryoglobulinemia. Skin grafting was beneficial.
mesh_terms: D003080:Cold Temperature / Q000009:adverse effects; D003450:Cryoglobulins / Q000032:analysis* / Q000145:classification; D005260:Female; D005734:Gangrene / Q000601:surgery*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D009336:Necrosis; D016038:Skin Transplantation; D014182:Transplantation, Autologous
chemical_list: D003450:Cryoglobulins; D007136:Immunoglobulins