Effects of protein deficiency on plasma levels of 25-hydroxyvitamin and 24,25-dihydroxyvitamin D in the rat.
The effect of protein deficiency on plasma 25-hydroxyvitamin and 24,25-dihydroxyvitamin D concentrations was determined in weanling rats. The concentrations of these metabolites did not differ in rats fed diet providing either 0.5 or 21% casein for 4 weeks postweaning. Also, no change was observed in plasma levels of these metabolites in rats fed the 21% casein diet in amounts restricted to those consumed by the 0.5% casein animals for the same period of time. The results indicate that the synthesis and transport of 25-hydroxyvitamin and 24,25-dihydroxyvitamin D are not significantly affected by either a protein deficiency or a total food striction during the early postweaning period. This finding may be relevant to the vitamin D status of children with kwashiorkor.
D015650:24,25-Dihydroxyvitamin D 3; D015652:25-Hydroxyvitamin D 2; D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D004032:Diet; D004100:Dihydroxycholecalciferols / Q000097:blood*; D006887:Hydroxycholecalciferols / Q000097:blood*; D008297:Male; D011488:Protein Deficiency / Q000378:metabolism*; D051381:Rats
D002364:Caseins; D004100:Dihydroxycholecalciferols; D006887:Hydroxycholecalciferols; D015652:25-Hydroxyvitamin D 2; D015650:24,25-Dihydroxyvitamin D 3