[Effect of alpha 1-protease inhibitor (alpha 1-antitrypsin) on the intensity of phytohemagglutinin stimulated lymphocyte transformation].
alpha 1-Antitrypsin (alpha 1-AT) decreases the intensity of human peripheral blood lymphocyte transformation stimulated by phytohemagglutinin. The degree of inhibition is influenced by the antiprotease activity of alpha 1-AT. It is shown that maximal inhibition of transplantation is 50%. Participation of alpha 1-AT in the control of biological activity of lymphoid tissue cells is suggested.
D006801:Humans; D007700:Kinetics; D037102:Lectins; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D000515:alpha 1-Antitrypsin / Q000494:pharmacology*
D037102:Lectins; D000515:alpha 1-Antitrypsin
Vliianie al'fa l-proteaznogo ingibitora (al'fa 1-antiripsina) na intensivnost' transformatsii limfotsitov, stimulirovannykh fitogemaggliutininom.