Peripheral blood lymphocytes and their subpopulations in lung carcinoma.
In 166 patients with lung carcinoma peripheral blood lymphocytes and their subpopulastions (AE-RFC, TE-RFC, EAC-RFC) were examined. In comparison with control--the mean values of the absolute counts of the blood lymphocytes did not show statistically significant changes in various stages of lung cancer. However, the count of active T lymphocytes as well as total T lymphocytes were slightly lowered in the stage I of the disease, and significantly decreased in stages II and III. The lowest decrease of T lymphocytes was found in adenocarcinoma and the greatest--in microcellular cancer.
D000230:Adenocarcinoma / Q000097:blood* / Q000276:immunology; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000097:blood* / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008175:Lung Neoplasms / Q000097:blood* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013601:T-Lymphocytes / Q000276:immunology