Usual interstitial pneumonitis in infancy. Clinical and pathologic evaluation.
Interstitial lung disease is uncommon in infancy and childhood, and the long-term clinical and pathologic evolution of this entity in infants has not been published previously. We describe an infant with a steroid-sensitive chronic interstitial pneumonitis for which the clinical and histopathologic progression of the disease are presented. A family history of interstitial pneumonitis consistent with an autosomal dominant trait was present, and Pneumocystis carinii were found in the lung biopsy specimen.
D001706:Biopsy; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000648:ultrastructure; D011010:Pneumocystis / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000235:genetics* / Q000382:microbiology / Q000473:pathology