title: Alpha-naphthyl acetate esterase activity in human adult and cord blood rosette forming cells.
abstract: Alpha-naphthyl acetate esterase (ANAE) activity was studied in cells forming rosettes with sheep and mouse erythrocytes. In adult peripheral blood, on the average 74% of E-rosette-forming cells expressed simultaneous focal ANAE activity, whereas most cells forming rosettes with mouse erythrocytes were negative. No difference was observed in ANAE-staining proportions of active and total E-rosette forming cells in adult peripheral blood. The proportions of total and active E-rosette and M-rosette forming cells were similar in adult peripheral blood and cord blood lymphocytes. However, the mean percentage of cord blood total E-rosette-forming cells expressing ANAE activity (61%) was significantly lower (P less than 0.001) than in adult peripheral blood.
mesh_terms: D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D004912:Erythrocytes / Q000276:immunology; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D007231:Infant, Newborn; D008214:Lymphocytes / Q000145:classification / Q000201:enzymology* / Q000276:immunology; D051379:Mice; D009283:Naphthol AS D Esterase / Q000378:metabolism*; D012397:Rosette Formation; D012756:Sheep; D013601:T-Lymphocytes / Q000145:classification / Q000201:enzymology / Q000276:immunology
chemical_list: D009283:Naphthol AS D Esterase; D002265:Carboxylic Ester Hydrolases