title: [Immunogenicity of leukemic cells during low-temperature freezing with different cryoprotectors].
abstract: Immunogenicity of leukemic cells was studied and compared during conservation with the three cryoprotectors, DMSO, DMAC, and PEO. Immunogenicity of leukemic cells was assessed from immune response of the experimental animals to immunization with these cells (the titer of cytotoxic antibodies and lymphocyte cytotoxicity). The data obtained indicate that immunogenicity of leukemic cells conserved with DMAC and PEO does not virtually differ from that of native cells or of cells conserved with DMSO.
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003451:Cryoprotective Agents / Q000494:pharmacology*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D006801:Humans; D007114:Immunization; D007939:Leukemia L1210 / Q000276:immunology*; D007945:Leukemia, Lymphoid / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013696:Temperature; D014021:Tissue Preservation
chemical_list: D003451:Cryoprotective Agents; D004121:Dimethyl Sulfoxide
vernacular_title: Immunogennost' leĭkoznykh kletok pri nizkotemperaturnom zamorazhivanii s razlichnymi krioprotektorami.