title: Ubiquitous nonimmunoglobulin p-azobenzenearsonate-binding molecules from lymphoid cells.
abstract: A ubiquitous nonimmunoglobulin molecule that binds p-azobenzenearsonate (ABA) has been detected in the cytoplasm of several murine cell lines, including T cell hybridomas as well as in normal liver and spleen. Similar to many recently described antigen-specific T cell factors, this ABA-binding protein has a 62,000 mol wt, and, when analyzed by direct binding, the molecule reacts with several different rabbit anti-idiotypic antisera specific to the ABA system. The presence of this antigen-specific, "idiotype positive" molecule in many different cells indicates that it is not an important immunoregulatory molecule.
mesh_terms: D000818:Animals; D001391:Azo Compounds / Q000276:immunology*; D001665:Binding Sites; D002352:Carrier Proteins / Q000378:metabolism; D003429:Cross Reactions; D006825:Hybridomas / Q000276:immunology; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D007136:Immunoglobulins / Q000276:immunology*; D051379:Mice; D008805:Mice, Inbred A; D011817:Rabbits; D013601:T-Lymphocytes / Q000276:immunology*; D010132:p-Azobenzenearsonate / Q000276:immunology* / Q000378:metabolism
chemical_list: D001391:Azo Compounds; D002352:Carrier Proteins; D007130:Immunoglobulin Idiotypes; D007136:Immunoglobulins; D010132:p-Azobenzenearsonate