title: [Immunity in hypothyroid children (author's transl)].
abstract: For a long time investigators have focused attention on the relationship between specific immunity and hormones. In the present paper, authors investigated on 26 children, 9 males and 17 females, from 9 months to 14 and 10/12 years old, with primary hypothyroidism. All patients were in substitutive treatment. The following studies were done to all the patients: serum IgG, IgA, IgM and complement. Blood lymphocyte counts, percentages of B and T lymphocytes, as well as the response of lymphocytes to PHA. Skin tests were also carried out: tuberculin, candidin and streptokinase-streptodornase. All results obtained in both, hypothyroid and control groups fell within the range of normal age-matched values for our laboratory, and by results of statistics studies carried out they were considered of little significance, except the percentage of circulating B lymphocytes that was lower in hypothyroid group (p less than or equal to 0.01).
mesh_terms: D000293:Adolescent; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000276:immunology*; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008297:Male; D012882:Skin Tests; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007136:Immunoglobulins; D003165:Complement System Proteins
vernacular_title: Estudio de la inmunidad en niños hipotiroideos.