title: [Histological findings in the skin of animals after percutaneous damage by hydrofluoric and hexafluorosilicic acid ].
abstract: Morphological changes in the skin of animals were studied after application of concentrated hydrofluoric and hexafluorosilicic acid. The intact skin was not generally affected by these acids. Areas injured before application of the acid showed, however, a continuous spreading of necrosis in the deeper regions. The first histological changes were noticed 1 h after the application. Such early histological findings could be seen long before any macroscopic reaction. The main characteristic findings were the hypocellular necrosis and edema reaching as far as the subcutis. The necrosis showed sharp leukocyte demarcations.
mesh_terms: D000818:Animals; D004817:Epidermis / Q000187:drug effects; D005459:Fluorides / Q000633:toxicity*; D005554:Forensic Medicine; D006168:Guinea Pigs; D006858:Hydrofluoric Acid / Q000633:toxicity*; D009336:Necrosis; D051381:Rats; D011917:Rats, Inbred Lew; D012824:Silicic Acid; D012825:Silicon / Q000633:toxicity*; D012867:Skin / Q000187:drug effects*; D013552:Swine
chemical_list: D012824:Silicic Acid; C035291:hexafluorosilicic acid; D005459:Fluorides; D006858:Hydrofluoric Acid; D012825:Silicon
vernacular_title: Histologische Befunde an der Tierhaut nach percutaner Schädigung durch Flusssäure and Hexafluorkieselsäure.