title: Health status of cable splicers with low-level exposure to lead: results of a clinical survey.
abstract: The results of a cross-sectional clinical field survey of 90 telephone cable splicers are presented. Despite the rare occurrence of clinically overt lead poisoning among cable splicers, the observed prevalence of symptoms was 29% for lead-associated central nervous system symptoms and 21% for gastrointestinal symptoms. These two groups of symptoms were directly related to zinc protoporphyrin (ZPP) levels but no relationship was found between them and blood lead concentrations. Only 5% of the workers had significantly elevated blood lead levels (greater than 40 microgram/100ml). Because of the intermittent lead exposure encountered in this trade, individuals were identified with "normal" blood lead levels associated with "elevated" zinc protoporphyrin concentrations, indicating the difference in biological significance between exposure-(blood lead) and biological-response tests (ZPP). Suggestion is made that both types of diagnostic tests be utilized in the medical surveillance of lead-exposured workers.
mesh_terms: D000328:Adult; D000368:Aged; D002493:Central Nervous System Diseases / Q000175:diagnosis; D003430:Cross-Sectional Studies; D005767:Gastrointestinal Diseases / Q000175:diagnosis; D006304:Health Status; D006801:Humans; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced / Q000453:epidemiology*; D011524:Protoporphyrins / Q000097:blood; D014481:United States; D015032:Zinc / Q000097:blood
chemical_list: D011524:Protoporphyrins; C017803:zinc protoporphyrin; D007854:Lead; D015032:Zinc