[Lesions of the lungs in children with acute leukemia].
Investigation of the lungs of 65 children who died of acute leukemia, revealed pathological alterations in 39 of them. Specific leukemic infiltration of the lung parenchyma was found in 29.3%, but it did not play an important role in tanathogenesis. Pneumonias were diagnosed in 46.1% of the observations being the main cause of death in 23%. The inflammatory processes showed a marked tendency for spread because of low immunologic responsiveness of the patients and poor neutrophil reaction. Because of this, segmental pneumonias predominated in our observations, and in 5 cases total bilateral interstitial pneumonias had developed. Three of them were due to Pneumocystis carinii and two were drug pulmonitis.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000473:pathology*; D007948:Leukemia, Monocytic, Acute / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D011014:Pneumonia / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000473:pathology
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