[Suppression of bone marrow colony-forming capacity by syngeneic T-lymphocytes in AKR strain mice with lymphoblastic leukemia].
The effect of lymphocytes from the lymph nodes and thymus on bone marrow colony-forming capacity was studied in AKR mice in the preleukemic and leukemic periods in vivo in the syngeneic donor-recipient system. In the pre-leukemic period, the lymphocytes do not change in the syngeneic stem cell colony-forming index, while in spontaneous lymphoblastic leukemia they suppress bone marrow proliferative activity both in normal and leukemic mice and 62-100%.
D000367:Age Factors; D000818:Animals; D001853:Bone Marrow / Q000276:immunology*; D003114:Colony-Forming Units Assay; D007945:Leukemia, Lymphoid / Q000276:immunology*; D008198:Lymph Nodes / Q000166:cytology; D051379:Mice; D008806:Mice, Inbred AKR; D011289:Preleukemia / Q000276:immunology*; D013601:T-Lymphocytes / Q000637:transplantation*; D013950:Thymus Gland / Q000166:cytology; D014185:Transplantation, Isogeneic
Ugnetenie kolonieobrazutiushcheĭ sposobnosti kostnogo mozga singennymi T-limfostsitami pri limfoblastnom leĭkoze u mysheĭ liniĭ AKR.