Ultrastructure of adult T-cell lymphoma.
A particular type of adult T-cell lymphoma which occasionally progress to leukemia has been widely accepted as endemic in a restricted area of Kyushu Island in the southwest part of Japan. This type of non-Hodgkin's lymphoma is called peripheral T-cell lymphoma, pleomorphic lymphoma or adult T-cell leukemia. In this report, the cellular characteristics of 34 cases of adult T-cell lymphoma-leukemia were analyzed by electron microscopy. The most prominent feature of adult T-cell lymphoma is nuclear pleomorphism, primarily characterized by nuclear convolution, multilobulation and fragmentation.
D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000145:classification / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D013601:T-Lymphocytes / Q000648:ultrastructure