Treatment of Hemophilus vaginalis vaginitis.
Four antimicrobial agents (triple sulfa cream, doxycycline, ampicillin, and metronidazole) were studied by double-blind techniques to determine their effectiveness in the treatment of Hemophilus vaginalis vaginitis, documented by vaginal culture in 96 patients. Cure was confirmed by negative vaginal cultures 7 weeks after the start of therapy. Metronidazole proved to be effective in 20 of 22 couples (90.9%) treated. Sulfa cream, doxycycline, and ampicillin were effective in 47.8 to 63.6% of patients treated.
D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006194:Gardnerella vaginalis; D006192:Haemophilus Infections / Q000188:drug therapy*; D006801:Humans; D008272:Mafenide / Q000627:therapeutic use; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D013409:Sulfacetamide / Q000627:therapeutic use; D000077589:Sulfathiazole; D013432:Sulfathiazoles / Q000627:therapeutic use; D014627:Vaginitis / Q000188:drug therapy*
D004338:Drug Combinations; D013432:Sulfathiazoles; D008795:Metronidazole; D013409:Sulfacetamide; D008272:Mafenide; D000667:Ampicillin; D004318:Doxycycline; D000077589:Sulfathiazole