title: Rosetting of bovine T-lymphocytes with autologous and allogeneic red blood cells.
abstract: Certain bovine peripheral blood lymphocytes (PBL) and foetal thymocytes were shown to bind autologous and allogeneic red blood cells (RBC). When autologous RBC were treated with dextran, approximately 10% of peripheral blood lymphocytes and about 30% of thymocytes were found to form rosettes. Cells forming autologous rosettes appear to be a population of T-lymphocytes because (1) more rosette formation occurred with thymocytes than with PBL, (2) autologous rosette formation was increased in PBL cultures enriched in T cells and was decreased in cultures depleted of T cells, (3) very few rosette forming cells had surface immunoglobulin and (4) peripheral blood mononuclear cell cultures depleted of monocytes did not show a decreased autologous rosette formation. It appears that the cells forming rosettes with autologous and allogeneic RBC belong to the same sub-population of T-cells.
mesh_terms: D000818:Animals; D000954:Antigens, Surface / Q000276:immunology*; D002417:Cattle; D002478:Cells, Cultured; D003429:Cross Reactions; D004912:Erythrocytes / Q000276:immunology; D012397:Rosette Formation; D012756:Sheep / Q000276:immunology; D013601:T-Lymphocytes / Q000145:classification / Q000276:immunology*
chemical_list: D000954:Antigens, Surface