The influence of naloxone on dental pain threshold elevation produced by peripheral conditioning stimulation at high frequency.
The phasic dental pain threshold elevation produced by high-frequency transcutaneous electrical nerve stimulation (TENS) in healthy humans was not abolished by naloxone. A prolonged (20 min) high-frequency TENS did not cause any tonic pain threshold elevation. The results indicate that opioid-dependent systems have only a minor if any contribution to alleviation of experimental pain during high-frequency TENS.
D000328:Adult; D003213:Conditioning, Psychological; D004558:Electric Stimulation; D004599:Electric Stimulation Therapy; D006801:Humans; D008297:Male; D009270:Naloxone / Q000627:therapeutic use*; D010146:Pain / Q000503:physiopathology; D059408:Pain Management
D009270:Naloxone