Short and long latency skin sensitizing antibody in passive cutaneous anaphylaxis in the monkey.
In some allergic sera, 2-hr PCA responses can be due to IgE class antibody. In other sera where 2-hr PCA responses are not seen, removal of the IgG fracton allows expression of this 2-hr latency PCA response, suggesting an initial competition for binding sites between IgG and IgE, or that IgG can act as a blocking antibody, preventing antigen from reaching the cell-bound IgE.
D000042:Absorption; D000818:Animals; D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D005591:Chemical Fractionation; D002848:Chromatography, DEAE-Cellulose; D006358:Hot Temperature; D006801:Humans; D007073:Immunoglobulin E; D007074:Immunoglobulin G; D008253:Macaca mulatta; D008925:Mites; D010323:Passive Cutaneous Anaphylaxis; D012756:Sheep; D012867:Skin / Q000276:immunology*; D013997:Time Factors
D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G; D007073:Immunoglobulin E