title: Clinical application of the HLA-B27 test in rheumatic diseases. A current perspective.
abstract: Testing for the histocompatibility antigen HLA-B27 has been suggested as a valuable diagnostic aid in patients with ankylosing spondylitis and associated spondyloarthropathies, and B27 typing is becoming more readily available commercially at a number of clinical pathology laboratories. A current evaluation of B27 typing as a diagnostic test is presented, together with some guidelines for the clinical application of this test in the diagnosis of certain rheumatic diseases.
mesh_terms: D001168:Arthritis / Q000175:diagnosis*; D001171:Arthritis, Juvenile / Q000175:diagnosis; D016918:Arthritis, Reactive / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006680:HLA Antigens; D006801:Humans; D008297:Male; D011379:Prognosis; D013167:Spondylitis, Ankylosing / Q000175:diagnosis
chemical_list: D006680:HLA Antigens