Binding of anti-idiotypic antibodies against human serum low density lipoprotein (LDL) to skin fibroblasts.
Specific rabbit antibodies against human serum low density lipoproteins (LDL) were prepared. These were injected into guinea pigs and anti-idiotypic antibodies against human LDL were recovered. The anti-idiotypic antibodies inhibited the binding of (125)I-labeled LDL to human skin fibroblasts.
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology* / Q000302:isolation & purification; D001667:Binding, Competitive; D005347:Fibroblasts / Q000276:immunology; D006168:Guinea Pigs; D006801:Humans; D007074:Immunoglobulin G; D007130:Immunoglobulin Idiotypes; D007457:Iodine Radioisotopes; D008077:Lipoproteins, LDL / Q000097:blood / Q000276:immunology* / Q000378:metabolism; D011817:Rabbits; D012867:Skin / Q000166:cytology
D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D007074:Immunoglobulin G; D007130:Immunoglobulin Idiotypes; D007457:Iodine Radioisotopes; D008077:Lipoproteins, LDL