A comparison of regulatory cells from rabbit spleen and appendix.
Both spleen and appendix of the rabbit contain two types of accessory cells that regulate the response of T-cells to concanavalin A. These accessory cells are found among non-T, non-B adherent cells and among B-cells. There is, so far, no evidence for a sequential interaction of these two cell types. In addition, there is an inhibitory adherent cell type in the appendix that interferes with the B-cell-regulated proliferative T-cell response.
D000818:Animals; D001065:Appendix / Q000166:cytology*; D001402:B-Lymphocytes / Q000276:immunology*; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology; D008213:Lymphocyte Activation; D011817:Rabbits; D013154:Spleen / Q000166:cytology*; D013601:T-Lymphocytes / Q000276:immunology*
D003208:Concanavalin A