Diabetic syndrome in the Chinese hamster induced with monosodium glutamate.
Neuronal necrosis in the arcuate and ventromedial hypothalamus regions is easily induced in 1-day-old Chinese hamsters by the administration of monosodium glutamate (MSG). New-born Chinese hamsters injected with MSG showed no sign of obesity, even when grown up, but apparently developed a diabetic syndrome.
D000818:Animals; D000831:Animals, Newborn; D006224:Cricetinae; D003412:Cricetulus; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000473:pathology*; D005951:Glucose Tolerance Test; D005971:Glutamates; D007031:Hypothalamus / Q000473:pathology; D007515:Islets of Langerhans / Q000473:pathology*; D012970:Sodium Glutamate
D005971:Glutamates; D012970:Sodium Glutamate