Combined effects of HLA matching and age in renal transplantation.
Recipient age and matching for the HLA-A and B antigens each influence the graft survival rate of cadaver kidney transplants by approximately 10%. These two factors are cumulative and have a combined effect of nearly 20%. Thus, other factors that have a relatively weak influence on graft success may have a combined effect that makes their clinical consideration highly relevant.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002102:Cadaver; D002648:Child; D006650:Histocompatibility Testing; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D014019:Tissue Donors