The frequency of mutant-specific killer precursors in related and unrelated mouse strains.
The frequency of mutant-specific cytotoxic T lymphocyte precursors (CTL-P) has been analyzed in several mouse strains. While H-2 antigens of responder strains have a limited influence on the frequency of major H antigen-specific CTL-P, the frequency of mutant-specific CTL-P can be equally as high in unrelated and related strains. In general, the frequency does not reflect the closeness of kinship between stimulator and responder.
D000818:Animals; D003601:Cytotoxicity Tests, Immunologic; D006183:H-2 Antigens / Q000235:genetics*; D006412:Hematopoietic Stem Cells / Q000276:immunology*; D008213:Lymphocyte Activation; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA; D008817:Mice, Mutant Strains; D013045:Species Specificity; D013602:T-Lymphocytes, Cytotoxic / Q000166:cytology / Q000276:immunology*
D006183:H-2 Antigens