Effects of Cs on acetylcholine induced current. Is ik1 increased by acetylcholine in frog atrium?
1.20 mM Cs+ ions reduce background current and decrease drastically the K+ depletion process, probably as a consequence of the reduction of iK1. The background current-voltage relationship becomes linear. 2. 20 mM Cs+ ions completely abolish the current induced by acetylcholine. 3. The possibility that the K+ current induced by acetylcholine is due to an increase of iK1 is discussed.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D016275:Atrial Function; D002586:Cesium / Q000494:pharmacology*; D004594:Electrophysiology; D008564:Membrane Potentials; D011893:Rana esculenta / Q000502:physiology*
D002586:Cesium; D000109:Acetylcholine