Helix pomatia receptors on rat T lymphocytes and bone marrow cells.
Helix pomatia (HP) receptors are present on approximately 60 percent of neuraminidase (NANAase)-treated rat T lymphocytes. The HP+ spleen cells (SpC) can be separated from HP-, immunoglobulin-bearing (Ig+) cells by affinity chromatography. The HP+ SpC mediate the local graft-versus-host reaction (GVHR). Less than 1% of rat lymphocytes bear both HP and Ig markers. Approximately 25% of Lewis rat bone marrow cells are HP+ (only 1% are HP+ Ig+), suggesting that the HP receptor may be a differentiation marker.
D000818:Animals; D001667:Binding, Competitive; D001853:Bone Marrow / Q000378:metabolism*; D001854:Bone Marrow Cells; D002469:Cell Separation; D005260:Female; D006372:Helix, Snails / Q000276:immunology*; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D011975:Receptors, Mitogen / Q000032:analysis*; D013601:T-Lymphocytes / Q000378:metabolism*
D011947:Receptors, Antigen, B-Cell; D011975:Receptors, Mitogen