title: Widespread panacinar emphysema with alpha-1-antitrypsin deficiency.
abstract: We report the clinical, laboratory and necropsy findings in the cases of two patients with homozygous alpha 1-antitrypsin deficiency with a widespread distribution of panacinar emphysema.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D011656:Pulmonary Emphysema / Q000209:etiology* / Q000473:pathology; D019896:alpha 1-Antitrypsin Deficiency