[Prostaglandins for the termination of pathological pregnancies in the 2d trimester].
Prostaglandins (PG) are currently the drugs of choice to terminate pathological 2nd trimester pregnancies. 6 different dose schedules of were are tested in 100 women with missed abortion, hydatidiform mole, and fetal malformations: extraamniotic PGF2 alpha, intravenous PGE2, intravenous sulprostone (2 schedules), and intramuscular sulprostone (2 schedules). All tested regimens were effective. Induction-to-abortion times and incidence of side effects were different. Extraamniotic PGF2 alpha and intramuscular sulprostone appear to be the most practicable regimens.
D000030:Abortion, Missed / Q000628:therapy; D000013:Congenital Abnormalities / Q000628:therapy; D015237:Dinoprost; D015232:Dinoprostone / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000628:therapy; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007751:Labor, Induced; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011453:Prostaglandins / Q000627:therapeutic use*; D011458:Prostaglandins E / Q000008:administration & dosage; D011459:Prostaglandins E, Synthetic / Q000008:administration & dosage; D011460:Prostaglandins F / Q000008:administration & dosage
D011453:Prostaglandins; D011458:Prostaglandins E; D011459:Prostaglandins E, Synthetic; D011460:Prostaglandins F; C016767:sulprostone; D015237:Dinoprost; D015232:Dinoprostone
Prostaglandine zur Beendigung pathologischer Schwangerschaften im II. Trimenon.