title: Who do barium ions imitate acetylcholine?
abstract: The action of 1-4 mM barium on bullfrog sympathetic ganglion cells was studied using voltage clamp. Barium imitated the action of muscarine, causing depolarization, increased input resistance, tendency to repetitive firing, and a specific inhibition of a slow small outward current termed the M current. Barium did not produce significant short-term inhibition of three other outward currents; the delayed rectifier, the calcium-dependent K current, and the A current.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D001464:Barium / Q000494:pharmacology*; D004553:Electric Conductivity; D004558:Electric Stimulation; D005728:Ganglia, Sympathetic / Q000187:drug effects / Q000502:physiology*; D009116:Muscarine / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D011892:Rana catesbeiana
chemical_list: D001464:Barium; D009116:Muscarine; D000109:Acetylcholine