Syngeneic bone marrow transplantation in a patient with metastatic neuroblastoma refractory to conventional therapy.
A child with metastatic neuroblastoma refractory to conventional chemotherapy was treated with lethal doses of chemotherapy and total body irradiation followed by syngeneic bone marrow transplantation. A complete remission was achieved. However, the tumor recurred after six months, and the patient succumbed to disseminated neuroblastoma nine months after marrow grafting.
D000970:Antineoplastic Agents / Q000008:administration & dosage; D016026:Bone Marrow Transplantation; D001859:Bone Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009447:Neuroblastoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy; D014185:Transplantation, Isogeneic
D000970:Antineoplastic Agents