The role of the medial prefrontal cortex in food intake in dogs.
Following destructions of the prefrontal medial brain area in dogs two basis changes were noticed: an increase in food intake (14 dogs--group I) and a decrease of food intake (16 dogs--group II). On the basis of a histological analysis one can conclude that the differences in size, site and depth of the lesions are responsible for the obtained results. The deep lesions involving the white and grey matter in FPG area between the III and V (Kreiner's atlas) frontal planes brought about the most pronounced increase in food intake. The lesions involving only the cortex or very broad lesions in the whole prefrontal medial area and also anterior lesions between the I and III frontal planes, or posterior lesions from the VI to VIII frontal planes decreased the food intake or caused no changes in it.
D000818:Animals; D004285:Dogs; D004435:Eating; D001068:Feeding and Eating Disorders / Q000145:classification / Q000503:physiopathology; D005625:Frontal Lobe / Q000473:pathology / Q000502:physiology*; D006801:Humans; D006963:Hyperphagia / Q000503:physiopathology