Epidermal growth factor is a major growth-promoting agent in human milk.
Human milk stimulates DNA synthesis in cell cultures in which growth has been arrested. The mitogenic activity of milk is neutralized by the addition of antibody to human epidermal growth factor. The results identify epidermal growth factor as a major growth-promoting agent in breast milk.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004815:Epidermal Growth Factor / Q000032:analysis / Q000494:pharmacology*; D005260:Female; D006801:Humans; D051379:Mice; D008895:Milk, Human / Q000032:analysis / Q000502:physiology*; D008934:Mitogens; D010455:Peptides / Q000494:pharmacology*
D008934:Mitogens; D010455:Peptides; D004815:Epidermal Growth Factor; D004247:DNA