Autoantibodies in patients with acute salpingitis caused by Chlamydia trachomatis.
Autoantibodies were investigated by the indirect immunofluorescence method in 10 women with salpingitis caused by Chlamydia trachomatis and in 22 controls. Smooth-muscle antibodies (SMA) of the IgG and IgM class and IgM-antinuclear antibodies (ANA) were found more frequently in patients with salpingitis than in controls (p = 0.024, p = 0.001 and p = 0.015, respectively), but the titres were low (10-80) in both groups. Other antibodies (IgG-ANA, glomerular antibodies, parietal cell antibodies and reticulin antibodies) were uncommon in both patients and in controls. An in virus and mycoplasma infections IgM-SMA occurred most often in the beginning of the disease.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D002690:Chlamydia Infections / Q000276:immunology*; D002692:Chlamydia trachomatis; D005260:Female; D006801:Humans; D009130:Muscle, Smooth / Q000276:immunology; D012488:Salpingitis / Q000209:etiology / Q000276:immunology*
D000974:Antibodies, Antinuclear; D001323:Autoantibodies