title: [Effect of azathioprine and prednisolone on recipients of xenografts presensitized with donor species-specific antigen (author's transl)].
abstract: Presensitization induced by pretreatment of the recipients with donor species-specific spleen antigen cannot be completely reversed by immunosuppressive drugs. However, there is a suppressive influence of the combined administration of azathioprine and prednisolone on hemagglutinating antibody production after transplantation as well as an effect on function and survival time of renal xenografts.
mesh_terms: D000818:Animals; D000941:Antigens; D001379:Azathioprine / Q000008:administration & dosage*; D004285:Dogs; D005589:Foxes; D007114:Immunization; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016030:Kidney Transplantation; D011239:Prednisolone / Q000008:administration & dosage*; D013045:Species Specificity; D013154:Spleen / Q000276:immunology; D013997:Time Factors; D014181:Transplantation Immunology; D014183:Transplantation, Heterologous
chemical_list: D000941:Antigens; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine
vernacular_title: Beeinflussung einer durch Antigenvorbehandlung induzierten Sensibilisierung xenogener Transplantatempfänger durch Azathioprin und Prednisolon.