title: Role of ipsilateral forebrain in lateral hypothalamic stimulation reward in rats.
abstract: The forebrain was ablated unilaterally to a level dorsal to the thalamus and anterior commissure. Ipsilateral lateral hypothalamic electrodes were then implanted and the animal was tested for self-stimulation behavior. Tests included an initial test for behavioral reactivity to changes in reward level and then two estimates of the quantitative relationships between stimulation parameters: the number-current and charge-duration relationships. Comparison between these findings and those known for intact rats suggest that the substrate for unilateral hypothalamic stimulation reward is not impaired by removal of the ipsilateral tissue.
mesh_terms: D000818:Animals; D001931:Brain Mapping; D003216:Conditioning, Operant / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology*; D004558:Electric Stimulation; D007026:Hypothalamic Area, Lateral / Q000502:physiology*; D008297:Male; D008474:Medial Forebrain Bundle / Q000502:physiology; D009043:Motor Activity / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012201:Reward; D012653:Self Stimulation / Q000502:physiology*; D013788:Thalamus / Q000502:physiology*