Subpopulations of human T lymphocytes. XVIII. T lymphocytes with receptors for IgE (T epsilon) in patients with primary immunodeficiency and hyperimmunoglobulinaemia E states.
Four of 18 patients with common variable immunodeficiency and one of eight patients with selective IgA deficiency had increased proportions of T epsilon cells. Three patients with common variable immunodeficiency and two with selective IgA deficiency had increased numbers of T epsilon cells. Three patients with common variable immunodeficiency had decreased numbers of T epsilon cells. Five of six patients with hyperimmunoglobulinaemia E had high proportions of T epsilon cells; this increase was not related to the elevated IgE levels.
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology*; D017098:IgA Deficiency; D007073:Immunoglobulin E / Q000276:immunology*; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011971:Receptors, Immunologic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D011971:Receptors, Immunologic; D007073:Immunoglobulin E