title: Genetic mapping of an H-2-associated antigen expressed on regulatory T cells.
abstract: T lymphocytes that serve regulatory functions in the generation of effector T cells to alloantigen and to altered syngeneic cells express a distinguishing H-2-associated cell surface marker that we have termed Ha. Genetic mapping studies with the B10.A(2R), B10.A(4R), B10.A(5R), and LG/Ckc lines of mice have delineated the locus determining the expression of Ha to the right of H-2K and left of H-2IB or within the I-A region. Thus  these regulatory T lymphocytes express Ia antigens.
mesh_terms: D000042:Absorption; D000818:Animals; D002874:Chromosome Mapping; D003429:Cross Reactions; D003602:Cytotoxicity, Immunologic; D006183:H-2 Antigens / Q000235:genetics*; D007106:Immune Sera / Q000276:immunology; D051379:Mice; D008805:Mice, Inbred A; D008810:Mice, Inbred C57BL; D011995:Recombination, Genetic; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D006183:H-2 Antigens; D007106:Immune Sera