Connective tissue activation. XXIII. Increased plasma levels of a platelet growth factor (CTAP-III) in patients with rheumatic diseases.
Plasma levels of the CTAP-III antigen were measured by radioimmunoassay in 80 patients with rheumatic diseases. Patients with clear evidence of vasculitis usually exhibited increased plasma CTAP-III antigen. In both systemic lupus erythematosus and rheumatoid arthritis, there appeared to be a correlation between pCTAP-III values and other laboratory and clinical parameters of disease activity.
D000941:Antigens / Q000302:isolation & purification; D001172:Arthritis, Rheumatoid / Q000097:blood; D003238:Connective Tissue / Q000378:metabolism*; D006133:Growth Substances / Q000302:isolation & purification*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood; D010455:Peptides / Q000302:isolation & purification*; D010982:Platelet-Derived Growth Factor; D011863:Radioimmunoassay; D012216:Rheumatic Diseases / Q000097:blood*
D000941:Antigens; D006133:Growth Substances; D010455:Peptides; D010982:Platelet-Derived Growth Factor