title: [Mechanism of duplication formation relating to a case of 10q22 to q25 duplication].
abstract: A duplication 10q22q25 was studied in the fetus of a mother carrier of a t(14q21q). On this occasion, duplications reported in the literature are reviewed. Chromosomal rearrangements involving two breaks always result in tandem duplications, while three break- rearrangements result in tandem or mirror adjacent duplications, or in non adjacent direct or inverted duplications, or in direct or inverted autointerstitial duplications.
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D000649:Amniocentesis; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D011247:Pregnancy
vernacular_title: Mécanismes de formation des duplications a propos d'une observation de duplication 10q22àq25.