Reduction of a subset of T cells bearing Fc receptors for IgG in lepromatous leprosy.
Enumeration of a subpopulation of T cells with receptors for the Fc portion of IgG (T gamma) in the peripheral blood of 14 normal subjects and 43 patients with leprosy was undertaken. Tuberculoid leprosy patients showed normal levels of T gamma cells. In contrast, bacillary positive patients with lepromatous leprosy revealed a significant reduction of circulating T gamma cells (p less than 0.001).
D001402:B-Lymphocytes / Q000276:immunology; D002469:Cell Separation; D006801:Humans; D007074:Immunoglobulin G; D007918:Leprosy / Q000276:immunology*; D011961:Receptors, Fc; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
D007074:Immunoglobulin G; D011961:Receptors, Fc