[Pharmacology of the venom from the scorpion, Buthus eupeus].
Reactions induced by venom from the scorpion Buthus eupeus and by toxin of the venom have been studied on isolated organs and tissues as well as on intact body. It has been shown that substances interfering with the conduction of nerve excitation, with the mediator storage and interaction of the latter with synaptic receptors prevent the reactions induced by the venom and toxin, whereas ganglion-blocking agents do not affect these reactions. The catecholamine content in rat blood plasma has been found to be increased. It is assumed that the venom and toxin that affect the postganglionic nerve terminals release mediator acetylcholine and noradrenaline.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D011896:Rana temporaria; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects; D011950:Receptors, Cholinergic / Q000187:drug effects; D012604:Scorpion Venoms / Q000494:pharmacology* / Q000633:toxicity; D013997:Time Factors
D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic; D012604:Scorpion Venoms
K farmakologii iada skorpiona Buthus eupeus.