Double-blind evaluation of cimetidine as an adjunct to the routine double contrast upper-gastrointestinal examination.
Cimetidine, an effective gastric hydrogen receptor antagonist, is evaluated as a secretion eliminator in a routine double contrast upper-gastrointestinal study to improve areae gastricae visualization. One-hundred patients in a double-blind study used cimetidine or a placebo. Results suggest that acid secretion blockage with limited dosage has no advantage in micromucosal visualization.
D000328:Adult; D002927:Cimetidine / Q000378:metabolism; D002986:Clinical Trials as Topic; D004064:Digestive System / Q000000981:diagnostic imaging*; D004311:Double-Blind Method; D005260:Female; D005753:Gastric Mucosa / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000378:metabolism; D006146:Guanidines; D006801:Humans; D008297:Male; D011859:Radiography; D013270:Stomach / Q000000981:diagnostic imaging
D006146:Guanidines; D002927:Cimetidine