title: Sequential use of drugs and alcohol: a reexamination of the stepping-stone hypothesis.
abstract: This study examines sequential use of various drugs and alcohol among 1544 subjects being treated for substance abuse in 10 treatment centers. Several models were developed to examine drug usage with respect to specific lags dealing with the number of years between periods of beginning use of different types of drugs. The models also assessed the relationships between the lags from first to regular use of specific drugs. Length of use and amount of the drug used first in a sequence are associated with the lag from regular use of that drug to regular use of another drug--especially when the initial drug is marijuana. Contrary to expectation, shorter lags from first to regular alcohol use point toward longer lags from regular alcohol use to use of other drugs. However, the lag from first to regular alcohol use is positively related to the lag from first to regular marijuana use.
mesh_terms: D000437:Alcoholism / Q000453:epidemiology*; D000704:Analysis of Variance; D003932:Heroin; D006556:Heroin Dependence / Q000453:epidemiology*; D006801:Humans; D013287:Illicit Drugs; D002189:Marijuana Abuse / Q000453:epidemiology*; D004364:Pharmaceutical Preparations; D013997:Time Factors
chemical_list: D013287:Illicit Drugs; D004364:Pharmaceutical Preparations; D003932:Heroin