title: [Need to consider various factors predisposing to chronic nonspecific lung diseases in pre-employment orientation. Current state of the studies and research].
abstract: The authors raise the problem of the factors predisposing to chronic nonspecific pulmonary diseases and the need to consider them in contemporary prophylaxis, especially in preemployment orientation. What is most important is bronchial hyperreactivity, accompanied by atopy or not, in the pathogenesis of asthma and spastic bronchitis, as well as disturbances of proteinases (elastase)--their inhibitors (alpha-1-antitrypsin) system in early emphysema pathogenesis.
mesh_terms: D000109:Acetylcholine; D001249:Asthma / Q000517:prevention & control*; D001985:Bronchial Provocation Tests; D001991:Bronchitis / Q000517:prevention & control*; D004796:Clinical Enzyme Tests; D004950:Esterases / Q000032:analysis; D006632:Histamine; D006801:Humans; D009787:Occupational Medicine; D010559:Personnel Management / Q000379:methods*; D010560:Personnel Selection / Q000379:methods*; D010641:Phenotype; D011030:Pneumothorax / Q000517:prevention & control*; D011112:Polymyxin B; D012106:Research; D019896:alpha 1-Antitrypsin Deficiency
chemical_list: D006632:Histamine; D004950:Esterases; D011112:Polymyxin B; D000109:Acetylcholine
vernacular_title: O potrzebie uwzgledniania niektórych czynników predysponujacych do przewlekłych nieswoistych chorób układu oddechowego w preorientacji zawodowej. Stan badań i poszukiwania.