T-lymphocyte subpopulations in patients with chronic dermatophytosis.
T lymphocytes with Fc receptors for IgM (Tm cells) or IgG (Tg cells), known under certain conditions to exert help or suppression, and T-helper and T-suppressor cells, defined by fluorescein-isothiocyanate-conjugated monoclonal antibodies, were determined in 7 patients with chronic dermatophytosis. There appeared to be a relation between severity of the disease and decreased proportion of Tm cells with concomitant increase of Tg cells. However, only in 1 severe case there was also a shift of T-helper and T-suppressor cells as defined by monoclonal antibodies.
D000328:Adult; D000906:Antibodies; D002908:Chronic Disease; D003881:Dermatomycoses / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000145:classification*; D014248:Trichophytin / Q000276:immunology
D000906:Antibodies; D014248:Trichophytin