title: [Therapeutic use of immunoglobulins in children (author's transl)].
abstract: The indications for immunoglobulin therapy in childhood have been well established for many years: prophylaxis is effective with single small doses, a full substitution needs multiple large applications. All other recommendations are ill-defined and result from wishful thinking rather than from solid clinical data. New is the possibility of safe i. v. Ig-application which could be realized through appropriate modification of gammaglobulin preparations. Some properties of the commercially available products are summarized. Our own experience with one of them is encouraging: as a matter of fact, fully effective gammaglobulin substitution is now possible in patients with antibody deficiency syndrome.
mesh_terms: D002648:Child; D004899:Erythroblastosis, Fetal / Q000517:prevention & control; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007153:Immunologic Deficiency Syndromes / Q000188:drug therapy; D007275:Injections, Intravenous; D011247:Pregnancy; D013742:Tetanus / Q000517:prevention & control; D014777:Virus Diseases / Q000517:prevention & control
chemical_list: D007136:Immunoglobulins
vernacular_title: Therapeutische Anwendung von Immunglobulinen bei Kindern.