Proliferative response to fluid injection in psoriatic and normal human epidermis.
Feulgen-DNA cytophotometry revealed that human epidermal cell proliferation is regulated at a pre-DNA synthetic phase and can be perturbed by mild trauma. Although uninvolved psoriatic skin appears clinically normal, its hypersensitivity indicates abnormal proliferative behaviour and may serve as a marker of latent disease.
D002453:Cell Cycle; D002455:Cell Division; D003584:Cytological Techniques; D004247:DNA / Q000096:biosynthesis; D000078404:Epidermal Cells; D004817:Epidermis / Q000473:pathology; D006801:Humans; D007271:Injections, Intradermal; D011565:Psoriasis / Q000473:pathology*; D012867:Skin / Q000166:cytology / Q000473:pathology*
D004247:DNA