Charcoal sorbent-induced hypolipidemia in uremia and diabetes.
Rats with hyperlipidemia associated with streptozotocin-induced diabetes or azotemia after subtotal nephrectomy were administered a diet containing 5% activated charcoal. Significant lowering of nonfasting serum cholesterol and triglyceride levels resulted. Charcoal-feeding also altered the abnormal high density lipoprotein electrophoresis pattern of diabetic rats toward normal.
D000818:Animals; D001806:Blood Urea Nitrogen; D002606:Charcoal / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D004591:Electrophoresis, Polyacrylamide Gel; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D009392:Nephrectomy; D051381:Rats; D011917:Rats, Inbred Lew; D014280:Triglycerides / Q000097:blood*; D014511:Uremia / Q000097:blood*
D008075:Lipoproteins, HDL; D014280:Triglycerides; D002606:Charcoal; D002784:Cholesterol