Emergence of rifampin-resistant Haemophilus influenzae.
Rifampin susceptibility of nasopharyngeal Haemophilus influenzae strains was determined before and after community-wide chemoprophylaxis with rifampin (children) and sequential minocycline-rifampin (adults). All strains were rifampin susceptible before prophylaxis, but 10.3% of the strains at 1 week and 7.5% of the strains at 9 weeks after prophylaxis were rifampin resistant.
D004352:Drug Resistance, Microbial; D006193:Haemophilus influenzae / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000494:pharmacology; D012293:Rifampin / Q000494:pharmacology*
D008911:Minocycline; D012293:Rifampin