title: Morphology of the spleen in women who died of metastatic genital tract cancer.
abstract: The histology of the white pulp of the spleen was assessed in 56 women who died of metastatic genital tract cancer and in 56 age-matched women who died of a myocardial infarction or a stroke. Special attention was paid to the areas associated with T cells and B cells. The T-cell and B-cell areas were profoundly depleted in patients with carcinoma. This suggests that women who die of genital tract cancer have impaired humoral and cell-mediated immunity.
mesh_terms: D000328:Adult; D000368:Aged; D001402:B-Lymphocytes; D002561:Cerebrovascular Disorders / Q000473:pathology; D005260:Female; D005833:Genital Neoplasms, Female / Q000276:immunology / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000276:immunology / Q000473:pathology; D013154:Spleen / Q000473:pathology*; D013601:T-Lymphocytes