title: Plasma levels of vitamin D metabolites in the bovine species during the perinatal period.
abstract: Plasma vitamin D metabolites (25-OH D; 24,25-(OH)2D and 1,25-(OH)2D) were measured simultaneously in the blood plasma samples of young cows and their calves. Four of the calves were chronically catheterized in utero at least 2 weeks before the expected time of parturition. No significant hypocalcaemia occurred in the dams at calving. Plasma vitamin D metabolites showed no significant variations for 2 weeks before and 4 days after calving. But rapid changes in plasma 1,25-(OH)2D concentrations were observed in one calf during the first 48 postnatal hours. Before birth, the maternal and foetal concentrations of either 1,25-(OH)2D or 24,25-(OH)2D were positively correlated. 25-(OH) D (13 ng/ml), 24,25-(OH)2D (1 ng/ml) and 1,25-(OH)2D (76 pg/ml) were detected in one foetal plasma collected 35 days before term.
mesh_terms: D015650:24,25-Dihydroxyvitamin D 3; D015652:25-Hydroxyvitamin D 2; D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000097:blood; D002417:Cattle / Q000097:blood*; D004100:Dihydroxycholecalciferols / Q000097:blood; D004872:Ergocalciferols / Q000031:analogs & derivatives / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D006887:Hydroxycholecalciferols / Q000097:blood; D011247:Pregnancy; D014807:Vitamin D / Q000097:blood*
chemical_list: D004100:Dihydroxycholecalciferols; D004872:Ergocalciferols; D006887:Hydroxycholecalciferols; D014807:Vitamin D; D015652:25-Hydroxyvitamin D 2; D015650:24,25-Dihydroxyvitamin D 3; D002117:Calcitriol; D002118:Calcium