DNA-synthesizing T and non-T cells in bacterial infections.
The results of autoradiographic determination of DNA-synthesizing lymphocytes (3H-thymidine) in 10 patients with bacterial infections were compared with results in 10 normal patients and contrasted with 23 CLL patients in different stages [12]. In patients with infectious diseases the absolute number of T cells was lower and the mean values of S-phase T cells and S-phase non-T cells was higher than in normal persons. In contrast to the patients with infections, CLL patients in stage o--III have lower S-phase T cell values and higher S-phase non-T cell values. In stage IV, on the other hand, all DNA-synthesizing lymphocytes are increased.
D000328:Adult; D000368:Aged; D001345:Autoradiography; D001424:Bacterial Infections / Q000473:pathology*; D004247:DNA / Q000096:biosynthesis*; D006801:Humans; D007945:Leukemia, Lymphoid / Q000473:pathology; D008214:Lymphocytes / Q000378:metabolism; D008875:Middle Aged; D013601:T-Lymphocytes / Q000378:metabolism
D004247:DNA