Surface markers of lymphocytes infiltrating seminoma tissue.
Infiltrating lymphocytes were separated from human seminoma tissue obtained surgically. The relative distributions of B and T lymphocytes, and a subset of T lymphocytes with IgG-Fc receptors were measured by the rosette-forming method in peripheral blood and in seminoma tissue from 7 patients with pure seminoma of the testis. The proportions of T and TG cells were increased in seminoma tissue compared to those of peripheral blood from the same patients, whereas the proportion of B cells did not change. This result might correlate with the favorable prognosis of seminoma usually accompanied with lymphocytic infiltration.
D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000648:ultrastructure*; D004407:Dysgerminoma / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011961:Receptors, Fc / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000648:ultrastructure*; D013736:Testicular Neoplasms / Q000648:ultrastructure*
D011961:Receptors, Fc