title: Dental extractions during anticoagulant therapy.
abstract: 1. 15 patients, whose therapy with the anticoagulant Coumarin was not discontinued, were observed for bleeding following dental extractions. 2. There was no significant bleeding in these patients as compared to 15 others whose Coumarin therapy was temporarily interrupted. 3. Patients with prosthetic heart valves should preferably be hospitalized for dental extractions. but Coumarin/anticoagulant therapy need not be discontinued. The procedures can safely be done within a therapeutic range of 20-30% P.T.
mesh_terms: D000328:Adult; D003374:Coumarins / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000209:etiology*; D013997:Time Factors; D014081:Tooth Extraction
chemical_list: D003374:Coumarins