[Morphometric study of the effect of 5-hydroxytryptophan on the activity of various hypothalamic centers in rats depending on the state of their sexual system].
The effect of 5-oxytryptophan (serotonin metabolic precursor), injected intraperitoneally to female rats (intact and with deafferented mediobasal hypothalamus) on the activity of a number of hypothalamic centres was studied. The activity of cells, both outside and inside the isolated area, proved to alter under the effect of 5-oxytryptophan. The direction of these effects depends on the initial state of the hypothalamic centres and on the hormone in whose presence serotonin acts.
D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure*; D004971:Estrus; D005260:Female; D007031:Hypothalamus / Q000648:ultrastructure*; D007032:Hypothalamus, Anterior / Q000648:ultrastructure; D007033:Hypothalamus, Middle / Q000648:ultrastructure; D007034:Hypothalamus, Posterior / Q000648:ultrastructure; D007620:Karyometry; D011247:Pregnancy; D051381:Rats
D006916:5-Hydroxytryptophan
Morfometricheskoe izuchenie vliianiia 5-oksitriptofana na aktivost' nekotorykh gipotalamicheskikh tsentrov u krys v zavisimosti ot sostoianiia ikh polovoĭ sistemy.