title: Activity of cephamandole against some gram-negative bacilli and staphylococci.
abstract: Sensitivity of cefamandole was tested in 560 strains including staphylococci and gram-negative bacilli. Staphylococcus aureus and Staphylococcus epidermidis strains were highly sensitive to cefamandole; beta-lactamase producers were slightly less sensitive. About 50% of gram-negative bacilli were sensitive to the concentration of cefamandole obtainable in serum, mainly to 15 micrograms/ml.
mesh_terms: D000421:Alcaligenes / Q000187:drug effects*; D002435:Cefamandole / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects*; D008826:Microbial Sensitivity Tests / Q000379:methods; D013210:Staphylococcus / Q000187:drug effects* / Q000201:enzymology; D001618:beta-Lactamases / Q000096:biosynthesis
chemical_list: D002511:Cephalosporins; D002435:Cefamandole; D001618:beta-Lactamases