An adherent, radiosensitive accessory cell necessary for mouse cytolytic T lymphocyte response to viral antigen.
A cell type in addition to T lymphocytes and macrophages was found to be necessary for the in vitro stimulation of mouse anti-Sendai viral T lymphocytes in response to subviral antigens. This cell type was found to be glass and nylon wool adherent, to bear no surface immunoglobulin or Thy 1.2 antigen, and to be radiosensitive. This type of cell was not needed when the stimulatory antigen was virus-infected cells.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D000956:Antigens, Viral; D002448:Cell Adhesion; D002469:Cell Separation; D003602:Cytotoxicity, Immunologic; D005260:Female; D007519:Isoantigens; D008264:Macrophages / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009757:Nylons; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology*
D000956:Antigens, Viral; D007519:Isoantigens; D009757:Nylons