title: Androgen receptor in the thumb pad of Rana esculenta: dynamic aspects.
abstract: The androgen receptor (dissociation constant, 6 x 10(-9) mol/l) present in the 105 000 g cytosol fraction of the thumb pad of Rana esculenta is hormone dependent. The number of testosterone binding sites decreased in the absence of the testes and in long-term castrated animals (75 days) became undetectable. Administration of testosterone (50 ng) induced the replenishment of the cytophasmic androgen receptor; its concentration also varied during the annual reproductive cycle.
mesh_terms: D000818:Animals; D001001:Anura; D002369:Castration; D003600:Cytosol / Q000378:metabolism; D005528:Foot / Q000378:metabolism; D008297:Male; D010507:Periodicity; D011893:Rana esculenta / Q000378:metabolism*; D011944:Receptors, Androgen / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D012727:Sex Characteristics; D013739:Testosterone / Q000494:pharmacology
chemical_list: D011944:Receptors, Androgen; D011987:Receptors, Steroid; D013739:Testosterone