Target cells for malignant catarrhal fever virus in rabbits.
Lymphocytes from lymph nodes and spleens of malignant catarrhal fever virus (MCFV) infected rabbits were tested for MCFV infectivity in secondary calf thyroid cell monolayers. Most infectivity was demonstrated in the lymphocytes. Some infectivity was also detected in macrophages/monocytes. It was thus concluded that lymphocytes form the major target cell for the herpesvirus of malignant catarrhal fever in rabbits.
D000818:Animals; D002417:Cattle; D006098:Granulocytes / Q000382:microbiology; D006564:Herpesviridae / Q000302:isolation & purification*; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000382:microbiology*; D008264:Macrophages / Q000382:microbiology; D008304:Malignant Catarrh / Q000382:microbiology*; D009000:Monocytes / Q000382:microbiology; D011817:Rabbits / Q000276:immunology / Q000382:microbiology*; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000382:microbiology