The enhancement of 5-fluorouracil anti-metabolic activity by leucovorin, menadione and alpha-tocopherol.
D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology*; D002452:Cell Count; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D004273:DNA, Neoplasm / Q000096:biosynthesis; D003857:Deoxyuridine / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005472:Fluorouracil / Q000494:pharmacology*; D005492:Folic Acid / Q000378:metabolism; D002955:Leucovorin / Q000494:pharmacology*; D004915:Leukemia, Erythroblastic, Acute / Q000378:metabolism / Q000473:pathology; D051379:Mice; D014810:Vitamin E / Q000494:pharmacology*; D014812:Vitamin K / Q000494:pharmacology*
D000963:Antimetabolites; D004273:DNA, Neoplasm; D014812:Vitamin K; D014810:Vitamin E; D005492:Folic Acid; D002955:Leucovorin; D005472:Fluorouracil; D003857:Deoxyuridine