Implantable oxygen microelectrode suitable for medium-term investigations of post-surgical tissue hypoxia and changes in tumor tissue oxygenation produced by radiotherapy.
Teflon-covered platinum oxygen probes were used to monitor tissue oxygen levels in post-surgical cancer patients and those treated with radiotherapy. Progressive wound healing was usually accompanied by a decrease in tissue pO2. Radiotherapy produced a slight increase in pO2 while hyperthermia effected a significant increase in the oxygen level during 100% oxygen breathing.
D000818:Animals; D002283:Carcinoma, Bronchogenic / Q000032:analysis; D004567:Electrodes, Implanted; D005260:Female; D005334:Fever / Q000209:etiology; D006258:Head and Neck Neoplasms / Q000032:analysis* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis* / Q000209:etiology; D008839:Microelectrodes; D010100:Oxygen / Q000008:administration & dosage / Q000032:analysis*; D010101:Oxygen Consumption / Q000528:radiation effects*; D010313:Partial Pressure; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology
D010100:Oxygen