[Evaluation of the adequacy of myocardial protection during aortocoronary shunting by electron microscopy data on intraoperative heart biopsies].
To evaluate the efficacy of combined cold and pharmacological protection of the myocardium in aortocoronary shunting, study of myocardial ultrastructure with quantitative stereological analysis of the mitochondria was conducted in 56 puncture biopsies; the material was collected in 28 patients with chronic ischemic heart disease before the aorta was clamped and after the clamp was removed. The period of anoxia did not exceed 68 minutes. The absence of irreparable morphological changes in the cardiomyocytes correlated with the character of restoration of cardiac activity and function after the operation, which allowed the conclusion that this is an effective method for protecting the myocardium of patients with chronic ischemic heart disease from anoxia during 68 minutes of cardioplegia.
D000328:Adult; D001706:Biopsy; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000473:pathology / Q000601:surgery; D006324:Heart Arrest, Induced; D006801:Humans; D007036:Hypothermia, Induced; D007430:Intraoperative Care; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009206:Myocardium / Q000648:ultrastructure*
Otsenka adekvatnosti zashchity miokarda pri aortokoronarnom shuntirovanii po dannym élektronnoĭ mikroskopii intraoperatsionnykh biopsií serdtsa.