Retinoids block ornithine decarboxylase induction in cells treated with the tumor promotor TPA or the peptide growth hormones, EGF and SGF.
D000818:Animals; D002262:Carboxy-Lyases / Q000096:biosynthesis*; D002460:Cell Line; D004790:Enzyme Induction / Q000187:drug effects; D004815:Epidermal Growth Factor / Q000037:antagonists & inhibitors; D006131:Growth Inhibitors; D007668:Kidney / Q000201:enzymology; D009955:Ornithine Decarboxylase / Q000096:biosynthesis*; D010704:Phorbols / Q000037:antagonists & inhibitors*; D051381:Rats; D012513:Sarcoma, Experimental / Q000503:physiopathology; D013755:Tetradecanoylphorbol Acetate / Q000037:antagonists & inhibitors*; D013997:Time Factors; D014212:Tretinoin / Q000494:pharmacology*
D006131:Growth Inhibitors; D010704:Phorbols; D014212:Tretinoin; D004815:Epidermal Growth Factor; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase; D013755:Tetradecanoylphorbol Acetate