Divergent blood pressure responses during short-term sodium restriction in hypertension.
In untreated patients with essential hypertension, daily sodium intake was reduced from 197 to 70 mEq/day in 82 outpatients and from 124 to 14 mEq/day in 25 patients in a metabolic ward. During the 10 days of sodium restriction 17% of the outpatients and 40% of the inpatients had mean blood pressure decreases of at least 10 mm Hg, but in 17% of the outpatients and 28% of the inpatients mean pressure rose at least 5 mm Hg. Most blood pressure decreases occurred in the group with high-renin hypertension. Our short-term experience suggests that dietary salt deprivation may not be effective treatment for all patients with hypertension and may even be counterproductive in some.
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D004039:Diet, Sodium-Restricted; D005260:Female; D006801:Humans; D006973:Hypertension / Q000178:diet therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood; D012964:Sodium / Q000652:urine; D013997:Time Factors
D012964:Sodium; D012083:Renin