title: The nature of allorosette-forming cells in rats.
abstract: ARFC appear in the spleen after transplantation of organs or tissues and immunization with nucleated cells between isohistogenic rat strains. The allorosette formation of rat spleen cells and T cells, isolated by an Ig-anti-Ig column, was examined. It has been demonstrated that 90% of ARFC are B cells and 10% are T cells. The allorosette phenomenon can therefore be considered an immune reaction concerning predominantly the B-cell system. Allorosette-forming T cells are discussed to be SD-antigen-recognizing cytotoxic T cells.
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D002469:Cell Separation; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012397:Rosette Formation; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*