title: Secondary structure prediction of sauvagine, a novel biologically active polypeptide from a frog.
abstract: The secondary structure of sauvagine has been predicted by the statistical method of Chou & Fasman. The results are compared with those obtained by the analysis of the secondary structure of the corticotropin releasing factor. The pattern of helices and beta-turns within these polypeptides is similar. Thus there is an evolutionary relationship in both sequence and secondary structure between these polypeptides, in accordance with their pharmacological properties.
mesh_terms: D000595:Amino Acid Sequence; D029845:Amphibian Proteins; D000818:Animals; D001001:Anura; D003346:Corticotropin-Releasing Hormone; D036361:Peptide Hormones; D010455:Peptides; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D014665:Vasodilator Agents
chemical_list: D029845:Amphibian Proteins; D036361:Peptide Hormones; D010455:Peptides; D014665:Vasodilator Agents; C025727:sauvagine; D003346:Corticotropin-Releasing Hormone