Genetic control of prophage induction in haemophilus influenzae after exposure to psoralen plus near-UV light.
Prophage S2 could be induced by psoralen plus near-UV light (PNUV) from a wild-type strain of Haemophilus influenzae, from UV light-sensitive strains uvr-1 and uvr-2 and PNUV-sensitive strains PSO1 amd PSO7, but not from a recombination-deficient strain, rec-1. The levels of prophage induction were comparable in the wild type and an ATP-dependent DNase-deficient strain, KW31, even though the PNUV-induced degradation in the latter strain was considerably lower. Prophage induction could be observed even with chloramphenicol present before, during, and 30 min after PNUV treatment.
D001426:Bacterial Proteins / Q000096:biosynthesis; D002701:Chloramphenicol / Q000494:pharmacology; D011564:Furocoumarins / Q000494:pharmacology; D005796:Genes; D006193:Haemophilus influenzae / Q000235:genetics* / Q000378:metabolism; D008242:Lysogeny; D014466:Ultraviolet Rays; D014775:Virus Activation
D001426:Bacterial Proteins; D011564:Furocoumarins; D002701:Chloramphenicol