Hybridization analysis of the methylated bases of Escherichia coli DNA.
The 5-methylcytosine residues of Escherichia coli DNA are randomly dispersed along the genome. Hybridization data indicate that these methyl moieties are transcribed at the same frequency as the total DNA. These results suggest that DNA methylation probably does not play a role in gene expression in bacteria.
D044503:5-Methylcytosine; D003596:Cytosine / Q000031:analogs & derivatives* / Q000032:analysis; D004269:DNA, Bacterial / Q000032:analysis*; D004926:Escherichia coli / Q000032:analysis*; D008745:Methylation; D009693:Nucleic Acid Hybridization
D004269:DNA, Bacterial; D044503:5-Methylcytosine; D003596:Cytosine