A monoclonal antibody to the HLA-A3 alloantigen.
Monoclonal antibody production recognizing the HLA-A3 antigen is described. The XI-23 antibody reacted with all of the 89 cell suspensions carrying the HLA-A3 antigen (100% cytotoxicity) among a total of 191 suspensions tested. No extra-reactivity or cross-reactivity was observed, particularly with that of HLA-A11. This antibody can thus be considered as a good HLA-typing reagent.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D003602:Cytotoxicity, Immunologic; D005260:Female; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D015791:HLA-A3 Antigen; D006432:Hemochromatosis / Q000235:genetics / Q000276:immunology; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D010375:Pedigree
D000911:Antibodies, Monoclonal; D006680:HLA Antigens; D015791:HLA-A3 Antigen