Fatal pulmonary hemorrhage due to nitrofurantoin.
Acute and chronic pleuropneumonic reactions as well as rare fatalities following nitrofurantoin exposure have been reported. A case of fatal fulminant hemorrhagic pneumonitis following nitrofurantoin exposure is reported here. Recent experimental evidence suggests that a toxic mechanism may be responsible for the observed reaction.
D000368:Aged; D004927:Escherichia coli Infections / Q000188:drug therapy; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male; D009582:Nitrofurantoin / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000188:drug therapy
D009582:Nitrofurantoin