title: [Specific and nonspecific cytolysis reactions in rheumatic patients with a low degree of activity in the process of combined treatment by a high-protein diet and drug preparations].
abstract: Effect of therapy including high-protein diet and hormones on specific and nonspecific cytolysis was studied in patients with torpid and latent-running recurrent rheumatic carditis. The number of HeLa cells on which specific antigens (cardiac tissue extract, collagen, group C streptococcal nucleoproteid) were adsorbed significantly decreased on addition to the test target sensitized lymphocytes from the patients examined. As a result of therapy most patients showed the reduced activity of supernatants obtained from peripheral blood lymphocyte cultures that were incubated with specific antigens.
mesh_terms: D000328:Adult; D001241:Aspirin / Q000008:administration & dosage; D002908:Chronic Disease; D003602:Cytotoxicity, Immunologic; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007113:Immunity, Innate; D007694:Killer Cells, Natural / Q000276:immunology; D008233:Lymphotoxin-alpha / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D012214:Rheumatic Heart Disease / Q000276:immunology* / Q000628:therapy
chemical_list: D004044:Dietary Proteins; D008233:Lymphotoxin-alpha; D011239:Prednisolone; D001241:Aspirin
vernacular_title: Izuchenie reaktsii spetsificheskogo i nespetsificheskogo tsitoliza u bol'nykh revmatizmom s maloĭ stepen'iu aktivnosti v protesse kompleksnogo lecheniia vysokobelkovoĭ dietoĭ i medikamentoznymi preparatami.