Activity of beta-lactamase produced by Bacteroides fragilis against newly introduced cephalosporins.
The purified beta-lactamase from Bacteroides fragilis hydrolyzed newly introduced cephalosporins including cefuroxime and HR 756, and was inhibited by 7 alpha-methoxylated cephalosporins such as 6059-S and YM09330.
D001441:Bacteroides fragilis / Q000201:enzymology*; D002511:Cephalosporins / Q000037:antagonists & inhibitors*; D004352:Drug Resistance, Microbial; D006868:Hydrolysis; D001618:beta-Lactamases / Q000494:pharmacology*
D002511:Cephalosporins; D001618:beta-Lactamases