[Loss of 2 kidney grafts due to recurrence of type II membrano-proliferative glomerulonephritis].
Recurrent glomerulonephritis after renal transplantation is seen in a very high percentage of patients with dense "deposit" disease (= membrano-proliferative glomerulonephritis type II). However, loss of graft due to recurrence is rare; only 4 cases have been reported. Two additional pediatric patients are described. Both had recurrent dense "deposit" disease with extracapillary proliferation and crescent formation. In one of them, a quiet initial phase of 20 months was followed by an extremely rapid progression of the disease leading to loss of graft function within 3 weeks.
D058186:Acute Kidney Injury / Q000209:etiology; D000293:Adolescent; D002648:Child; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000276:immunology*; D006084:Graft Rejection; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use; D014184:Transplantation, Homologous
D003520:Cyclophosphamide; D011241:Prednisone
Verlust zweier Nierentransplantate infolge Rezidivs einer membrano-proliferativen Glomerulonephritis Typ II.