Protein AA and lattice corneal dystrophy.
A 73-year-old woman underwent corneal transplantation because of lattice dystrophy. Histopathologic examination of the excised host cornea disclosed eosinophilic deposits that stained positively with Congo red and showed green birefringence with polarized light. Immunofluorescent examination showed protein AA and protein AP in the stromal deposits. To the best of our knowledge, this is the first report of protein AA and protein AP in the amyloid deposits of lattice corneal dystrophy.
D000368:Aged; D000682:Amyloid / Q000032:analysis*; D003315:Cornea / Q000032:analysis*; D003317:Corneal Dystrophies, Hereditary / Q000235:genetics / Q000503:physiopathology* / Q000601:surgery; D016039:Corneal Transplantation; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D000685:Serum Amyloid A Protein / Q000032:analysis*; D014184:Transplantation, Homologous
D000682:Amyloid; D000685:Serum Amyloid A Protein