title: [Nuclear magnetic resonance study of the conformation of nucleotides, oligonucleotides, and their analogs in solution. IV. Syn--anti-equilibrium in aqueous solutions of 2'-deoxynucleosides and nucleotides].
abstract: The method of determination of syn-anti-equilibrium constants by experimental measuring of spin-lattice relaxation rates of the H (1') atom of the carbohydrate ring recently elaborated by us for the ribonucleosides and nucleotides was applied to deoxy compounds. For calculation of the contribution of the H (2') and H (2") nuclei rapid relaxation to the relaxation rate of H (1'), the emprical expression was proposed. Conformation situation in aqueous solution of 2'-deoxynucleoside 5'-phosphates and pyrimidine 2'-deoxynucleosides was demonstrated to be characterized by the substantial preponderance of the anti-state. In the solution of dGuo and dAdo the relative weight of the anti-population was decreased to 0.5 and 0.3, respectively. The time average values of glycosidictorsional angle chi in the anti-state was calculated.
mesh_terms: D003838:Deoxyadenine Nucleotides; D003839:Deoxyadenosines; D003841:Deoxycytidine; D003843:Deoxycytidine Monophosphate; D003848:Deoxyguanine Nucleotides; D003849:Deoxyguanosine; D003853:Deoxyribonucleosides; D009682:Magnetic Resonance Spectroscopy; D009690:Nucleic Acid Conformation; D009711:Nucleotides
chemical_list: D003838:Deoxyadenine Nucleotides; D003839:Deoxyadenosines; D003848:Deoxyguanine Nucleotides; D003853:Deoxyribonucleosides; D009711:Nucleotides; D003841:Deoxycytidine; D003843:Deoxycytidine Monophosphate; D003849:Deoxyguanosine
vernacular_title: Izuchenie metodom iadernogo magnitnogo rezonansa konformatsii nukleotidov, oligonukleotidov i ikh analogov v rastvore. IV. Sin-anti-ravnovesie v vodnykh rastvorakh 2'-dezoksinukleozidov i nukleotidov.