title: [Variations in serum levels of C-reactive protein in severe head injury patients (author's transl)].
abstract: The variations of fibrinogen, alpha-antitrypsin, haptoglobin and C-reactive protein (CRP) were compared in sera from patients with a cranial trauma. All these protein concentrations were increased with CRP variation being the most marked and the most rapid. The prognostic and diagnostic value of CRP determination was studied in a series of 88 patients selected according to their clinical evolution. Four typical serum patterns of CRP were obtained according to the evolution of cranial trauma. The validity of this classification was tested in blind on 324 patients. The authors propose to determine daily serum CRP for four days after a trauma in order to survey its evolution. This biochemical information has to be added to the clinical data.
mesh_terms: D002097:C-Reactive Protein / Q000032:analysis*; D006259:Craniocerebral Trauma / Q000097:blood*; D005340:Fibrinogen / Q000032:analysis; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007700:Kinetics; D013997:Time Factors; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D006242:Haptoglobins; D000515:alpha 1-Antitrypsin; D005340:Fibrinogen; D002097:C-Reactive Protein
vernacular_title: Les variations sériques de la protéine C-réactive chez les traumatisés crâniens séveres.