Variation of the radiobiological oxygen constant, K, with the proliferative activity of the cells.
The value of K for mouse Ehrlich ascites cells depends on their phase of growth. Cells were grown either in vitro or in vivo but were irradiated and assayed in vitro. K was 1.7 times greater for cells in the exponential phase of growth than for those in plateau phase irrespective of the pre-irradiation growth conditions.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology / Q000532:radiotherapy; D002455:Cell Division / Q000528:radiation effects*; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D007399:Interphase / Q000528:radiation effects; D007700:Kinetics; D051379:Mice; D008954:Models, Biological; D010100:Oxygen; D011836:Radiation Tolerance
D010100:Oxygen