Hypothalamic neurons responsive to increased plasma level of testosterone in the male rat.
Unitary activity was recorded from several forebrain structures. Out of 108 cells, 35 reacted to a testosterone i.v. injection by an increase (24 cells) or a decrease (11 cells) of firing rate. This response was early (latency: 5.0 +/- 0.6 min), lasted 25.7 +/- 1.9 min and was reproducible. Responsive neurons were found to be significantly more numerous in the lateral hypothalamic area than in other structures.
D000818:Animals; D005071:Evoked Potentials / Q000187:drug effects; D007031:Hypothalamus / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008474:Medial Forebrain Bundle / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D051381:Rats; D013739:Testosterone / Q000008:administration & dosage / Q000097:blood*
D013739:Testosterone