title: [Radioisotopic study of the nasal muco-ciliary clearance (author's transl)].
abstract: The authors propose a method for the investigation of the muco-ciliary function of the nasal mucosa: they record the motion of radioactive particles, which are put by sonic nebulisation on nasal mucosa. The average speed is calculated by means of the analysis of sequential images and by the study of the variation of activity in relation to time in several main zones. A half-clearing time of the initial activity is also measured. The average speed is 8.33 mm/minute for normal persons and 2.36 mm/minute for a group of patients. This simple, accurate, non aggressive method is used for pharmacodynamic tests.
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology; D002923:Cilia / Q000000981:diagnostic imaging* / Q000502:physiology; D006801:Humans; D009278:Naphazoline / Q000627:therapeutic use; D009297:Nasal Mucosa / Q000000981:diagnostic imaging* / Q000502:physiology; D011877:Radionuclide Imaging; D012220:Rhinitis / Q000188:drug therapy / Q000503:physiopathology; D012223:Rhinitis, Vasomotor / Q000188:drug therapy / Q000503:physiopathology; D013667:Technetium
chemical_list: D013667:Technetium; D000255:Adenosine Triphosphate; D009278:Naphazoline
vernacular_title: Etude du drainage muco-ciliaire nasal par méthode radioisotopique.