Nonspecific acid esterase activity in human autologous rosette-forming lymphocytes.
Alpha-naphthyl acetate esterase (ANAE) distribution was studied in human peripheral blood total T cells (E-RFC) and in T lymphocyte subpopulation: Autologous rosette-forming cells (A-RFC) obtained in different conditions. The percentage of ANAE localized forms is always lower in A-RFC than in E-RFC, showing an immature state of these autoreactive cells. Among the A-RFC, the percentage of localized forms is correlated with the avidity of cells for autologous erythrocytes, suggesting linkage between A-RFC immaturity and avidity.
D000328:Adult; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D006801:Humans; D009283:Naphthol AS D Esterase / Q000097:blood*; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000201:enzymology*
D009283:Naphthol AS D Esterase; D002265:Carboxylic Ester Hydrolases