Radiation cataractogenesis in the amphibian lens.
This report describes a reproducible and characteristic sequelae for radiation cataractogenesis in the amphibian. The development of lens opacification was investigated as a function of dose and time after X-irradiation of the eye of postmetamorphic bullfrogs. It was found that the development of radiation cataracts in frogs is both age and dose dependent. It was also determined that, far from being radiation resistant, frog lenses are sensitive to doses that are moderately cataractogenic for mammals.
D000367:Age Factors; D000818:Animals; D002386:Cataract / Q000209:etiology* / Q000473:pathology; D007908:Lens, Crystalline / Q000528:radiation effects*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D011892:Rana catesbeiana