title: The influence of the size of the lens in ocular disease.
abstract: The mechanism of normal lens growth is considered. This involves both the surface accretion of new fibres and the central compaction of aging fibres. When lens growth is abnormal, it is shown to be retarded in most conditions, but accelerated in diabetes. The relationship between lens growth and ocular disease, in particular angle-closure glaucoma, is discussed.
mesh_terms: D000375:Aging; D002386:Cataract / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000503:physiopathology; D005128:Eye Diseases / Q000503:physiopathology*; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D007908:Lens, Crystalline / Q000254:growth & development*