Bilateral choroidal osteomas associated with fatal systemic illness.
An 11-year-old black boy complained of intermittent occipital headaches with nausea and projectile vomiting. Previous skin and lung biopsy specimens were interpreted as histiocytosis X. Cranial computed tomographic scanning disclosed a mass lesion in the region of the choroid plexus of the left lateral ventricle. This was surgically removed but proved nondiagnostic despite extensive histologic examination. An ophthalmologic evaluation showed discrete, elevated, yellow-white choroidal tumors in both maculas. The ophthalmoscopic appearance, as well as ultrasonography and computed tomography, led to the diagnosis of choroidal osteomas.
D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery / Q000648:ultrastructure; D002552:Cerebral Ventricles / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002830:Choroid Neoplasms / Q000175:diagnosis*; D004803:Eosinophilic Granuloma / Q000175:diagnosis; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008171:Lung Diseases / Q000175:diagnosis; D008297:Male; D008854:Microscopy, Electron; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010016:Osteoma / Q000175:diagnosis*; D012871:Skin Diseases / Q000175:diagnosis