Insulin permeability of hydrophilic polyacrylate membranes.
The diffusive permeability of insulin in polyhydroxyethyl methacrylate (37.1% water), polyhydroxyethyl acrylate (51.8% water), polymethacrylic acid (67.5% water), and cuprophane PT-150 membranes was determined and correlated with the weight fraction of water in the membrane. Insulin diffusivity in the membranes was determined to be 1.0 x 10(-6) cm2/sec, which is in reasonable agreement with literature values for insulin diffusivity in water.
D000179:Acrylates; D004058:Diffusion; D007328:Insulin; D008567:Membranes, Artificial; D010539:Permeability; D011108:Polymers
D000179:Acrylates; D007328:Insulin; D008567:Membranes, Artificial; D011108:Polymers