Biochemical pharmacology of lipophilic diaminopyrimidine antifolates in mouse and human cells in vitro.
D000818:Animals; D002478:Cells, Cultured; D003857:Deoxyuridine / Q000378:metabolism; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D007700:Kinetics; D002955:Leucovorin / Q000378:metabolism; D008727:Methotrexate / Q000494:pharmacology; D051379:Mice; D011743:Pyrimidines / Q000494:pharmacology*; D012995:Solubility; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism
D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013762:Tetrahydrofolate Dehydrogenase; D002955:Leucovorin; D003857:Deoxyuridine; D008727:Methotrexate