alpha-globin gene deletions associated with Hb J Tongariki.
Three identical alpha + thalassemia genes, one of which always carried the Hb J Tongariki mutation, have been observed in Vanuatuans. Despite the fact that at least two of them have arisen by different types of crossover event, the expression of all three haplotypes is identical.
D002872:Chromosome Deletion; D002902:Chromosomes, Human, 16-18; D004247:DNA; D005796:Genes; D005914:Globins / Q000235:genetics*; D006448:Hemoglobin J / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D010375:Pedigree; D010641:Phenotype; D013789:Thalassemia / Q000235:genetics*; D009514:Vanuatu
D006455:Hemoglobins, Abnormal; D006448:Hemoglobin J; D005914:Globins; D004247:DNA; C034793:hemoglobin J Tongariki