Surface alterations of mammalian cells upon ionizing radiation as detected by lectin-binding technique. II. Binding of concanavalin A by human blood cells X-irradiated in vitro.
Early, dose-dependent and transient alterations were observed in the plasma membranes of human blood cells after X-irradiation in vitro as detected by a concanavalin A-binding technique. Platelets, lymphocytes and erythrocytes, separated in a one-step procedure from a single blood sample, showed different radiosensitivities within the dose range of 0.1--5 Gy. The complex evaluation of the surface alterations of blood cells might indicate the range of the absorbed dose.
D001665:Binding Sites; D001773:Blood Cells / Q000528:radiation effects*; D001792:Blood Platelets / Q000528:radiation effects; D002462:Cell Membrane / Q000528:radiation effects; D002470:Cell Survival; D003208:Concanavalin A / Q000378:metabolism*; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes / Q000528:radiation effects; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000528:radiation effects; D014316:Tritium; D014965:X-Rays
D014316:Tritium; D003208:Concanavalin A