title: Microvascular surgery.
abstract: In situations where existing techniques of reconstruction are inadequate or involve multiple stages, free-flap transfer offers major advantages for the head and neck surgeon. Wider application of free-flap surgery has been inhibited by problems of flap design and graft take. Thrombosis at the microanastomic site, particularly at the venous site, is still a cause of failure. Techniques of anastomosis are of paramount importance. Nakayama ring pin anastomosis is easier to learn, less time-consuming, and shows less early thrombosis that suture techniques. Use of adjunctive pharmacologic agents, such as the tetrahydroimidazo quinazolines, will increase the likelihood of success.
mesh_terms: D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D008866:Microsurgery / Q000379:methods*; D010974:Platelet Aggregation / Q000187:drug effects; D011799:Quinazolines / Q000494:pharmacology; D013518:Surgery, Plastic / Q000379:methods; D013524:Surgical Flaps; D013536:Suture Techniques; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D007093:Imidazoles; D011799:Quinazolines