title: [Appearance of hepatitis B in a family environment].
abstract: The study comprised 20 families with total of 83 members of whom 45 with hepatitis B. The selection was made of families with at least two members diseased which was the most common case, the marital couples being in question. Of other families, three families had three members and one family four members with hepatitis B virus infection. The largest number had severe clinical picture (44%) and 13 (28%) chronic active hepatitis. Four patients with the most severe clinical picture of chronic active hepatitis, together with HBeantigens, had positive HBeantigen for more than two years since the onset of the disease. Importance of damaged skin and mucosa in spreading of hepatitis B infection in family environment has been pointed out.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis / Q000235:genetics* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens
vernacular_title: Javljanje hepatitis B infekcije u porodicnoj sredini.