Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) associated with normal-pressure hydrocephalus Anatomoclinical report of one case.
The occurrence of two different dementing diseases, Creutzfeldt-Jakob disease and normal-pressure hydrocephalus in a single patient is described. The inefficacy of a shunt procedure in this particular case, and the need of a brain biopsy in patients with normal-pressure hydrocephalus before undergoing cerebrospinal fluid shunting are stressed. A purely coincidental occurrence, or a possible aetiopathogenic relationship between both diseases are postulated.
D000328:Adult; D001921:Brain / Q000473:pathology; D002557:Cerebrospinal Fluid Shunts; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000150:complications*; D006850:Hydrocephalus, Normal Pressure / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008297:Male