title: 25-hydroxyvitamin D in patients with essential hypertension.
abstract: Plasma 25-OH-D levels of normotensive and hypertensive subjects living in a highly industrial and in a nonindustrial area, were estimated. Significantly higher values were found in normotensive subjects than in hypertensive patients. Severity of arterial hypertension was not related to plasma 25-OH-D. Both groups of subjects (normotensive and hypertensive) living in the industrial area with high air pollution had lower 25-OH-D concentrations than those living in the nonindustrial region. Data presented in this paper suggest that antihypertensive treatment by pharmacologic agents exerts a depressive effect on plasma 25-OH-D level.
mesh_terms: D015652:25-Hydroxyvitamin D 2; D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects; D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D004872:Ergocalciferols / Q000031:analogs & derivatives* / Q000097:blood; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000494:pharmacology / Q000627:therapeutic use; D006973:Hypertension / Q000097:blood* / Q000188:drug therapy; D007221:Industry; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood
chemical_list: D000393:Air Pollutants; D004872:Ergocalciferols; D010710:Phosphates; D006852:Hydrochlorothiazide; D015652:25-Hydroxyvitamin D 2; D000469:Alkaline Phosphatase; D002118:Calcium