[Immunomodulating action of levamisol preparation in the treatment of trichinellosis (author's transl)].
The effect of Levamisol administered to patients with trichinosis, the influence thereof on the behaviour of lymphocytes T and B in the peripheral blood as well as the clinical course of the disease were analysed. In the 4th week Levamisol was administered to the patients in doses of 150 mg/24 h for 3 days and the same dose was given for 7 days in the 2nd and 4th week of the disease. The control group included patients with trichinosis who had not been given any drugs to produce immunological processes. A slight decrease in the percentage of T lymphocytes in the peripheral blood was observed in patients who had received Levamisol, immediately after having begun treatment. An increase in the percentage of T lymphocytes was noted in the patients who were treated with the drug as early as in the 2nd week of the disease. In patients treated with Levamisol, subjective complaints were observed which, however, ceased soon afterwards. No side effects of the drug were found.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000187:drug effects*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D007978:Levamisole / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000187:drug effects*; D014235:Trichinellosis / Q000097:blood* / Q000188:drug therapy
D007978:Levamisole
Immunmodulatorische Wirkung des Präparates Levamisol in der Behandlung der Trichinellose.