[Role of immune cytolysis and its thymosin stimulation in experimental influenza].
In experiments on C57BL and CC57W mice the acute or chronic course of experimental influenza infection has been shown to correlate with the activity of immune cytolysis. At a low level of the cytolytic activity of T-lymphocytes the prolonged persistence of influenza virus develops. The stimulation of cell-mediated immunity with thymosin prevents the development of chronic influenza infection.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D007111:Immunity, Cellular / Q000187:drug effects; D009980:Influenza A virus / Q000302:isolation & purification; D008168:Lung / Q000276:immunology / Q000382:microbiology; D051379:Mice; D008810:Mice, Inbred C57BL; D009976:Orthomyxoviridae Infections / Q000276:immunology* / Q000382:microbiology; D013268:Stimulation, Chemical; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013947:Thymosin / Q000276:immunology*; D013951:Thymus Hormones / Q000276:immunology*; D013997:Time Factors
D013951:Thymus Hormones; D013947:Thymosin
Rol' immunnogo tsitoliza i ego stimuliatsii timozinom v techenii éksperimental'noĭ infektsii.