Morphological evidence for the stimulatory effect of insulin on vaginal and endometrial cells of rats.
The effect of insulin (single subcutaneous injection 3 IU/100 g body weight) on the vaginal epithelium cells was studied in castrated adult female rats. At the electron-microscopic level, the vaginal cells showed development of the Golgi complexes and increase in the number and arrangement of ribosomes and secretory vesicles. The endometrial cells showed similar modifications, with stronger evidence of neoformation of polyribosomes. These results suggest that insulin stimulates the cellular activity of the vaginal and endometrial epithelia of castrated female rats.
D000818:Animals; D002369:Castration; D002466:Cell Nucleolus / Q000648:ultrastructure; D004717:Endometrium / Q000187:drug effects* / Q000648:ultrastructure; D005260:Female; D006056:Golgi Apparatus / Q000648:ultrastructure; D007328:Insulin / Q000494:pharmacology*; D009940:Organoids / Q000648:ultrastructure; D051381:Rats; D012270:Ribosomes / Q000648:ultrastructure; D014621:Vagina / Q000187:drug effects* / Q000648:ultrastructure
D007328:Insulin