title: [Derivation of a formula based on the central-limit theorem for evaluating the effectiveness of immunization].
abstract: The theoretical formula for the determination of the degree of resistance in the animal immunized with equal doses of the antigen has been deduced in accordance with the known of Kapteyn by presenting the immunological transformation of the organism, caused by the introduction of the antigen, as the result of the consecutive action of a multitude of accidental independent or slightly connected reasons and by using the liminal infective dose as the quantitative index of this transformation.
mesh_terms: D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D005069:Evaluation Studies as Topic; D007114:Immunization; D007158:Immunologic Techniques; D008433:Mathematics; D051379:Mice; D013745:Tetanus Toxoid / Q000008:administration & dosage
chemical_list: D013745:Tetanus Toxoid
vernacular_title: Vyvod formuly dlia otsenki éffektivnosti immunizatsii na osnove tsentral'noĭ predel'noĭ teoremy.