Infection of mice by aerosols of Klebsiella pneumoniae under hyperbaric conditions.
Both the physical behavior of aerosols and survival of airborne Serratia marcescens in hyperbaric chambers with a helium-air mixture at 20 atm of pressure was approximately the same as in the system at ambient pressures. Exposure of mice to aerosols of Klebsiella pneumoniae at 1-, 2-, and 17-atm (ca. 101-, 203-, and 1,722-kPa) pressures of helium-oxygen mixture showed that the number of viable organisms constituting a 50% lethal dose was not significantly affected by the hyperbaric conditions.
D000336:Aerosols; D000399:Air Pressure; D000818:Animals; D001274:Atmospheric Pressure; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000472:pathogenicity*; D007928:Lethal Dose 50; D051379:Mice; D009326:Naval Medicine / Q000379:methods*; D012706:Serratia marcescens / Q000254:growth & development
D000336:Aerosols