title: Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli.
abstract: Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon (I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.
mesh_terms: D002874:Chromosome Mapping; D004768:Enterotoxins / Q000494:pharmacology; D004926:Escherichia coli / Q000235:genetics* / Q000472:pathogenicity; D007421:Intestine, Small / Q000382:microbiology; D009154:Mutation
chemical_list: D004768:Enterotoxins