[Autograft of pancreatic tissue in the spleen of pancreatectomized dogs].
The intrasplenic autotransplant of pancreatic fragments in dogs subjected to total pancreatectomy can prevent diabetes as it maintains normoglycaemic condition and a normal insulinaemic response to i.v. infusion of glucose. By adopting a pancreatic tissue preparation technique which provides for a very short collagenasis digestion time (4 minutes), B cells took and normal glucidic metabolism was maintained.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000517:prevention & control; D004285:Dogs; D005260:Female; D007328:Insulin / Q000097:blood; D008297:Male; D016035:Pancreas Transplantation; D010180:Pancreatectomy; D011182:Postoperative Care; D013154:Spleen / Q000601:surgery*; D014182:Transplantation, Autologous
D001786:Blood Glucose; D007328:Insulin
Autotrapianto di tessuto pancreatico nella milza di cani pancreatectomizzati.