title: Aplasia cutis congenita.
abstract: Aplasia cutis congenita is an uncommon condition; fewer than 300 cases have been reported in the literature. Usually, the condition occurs as a focal scalp ulcer, but it may involve the full thickness of the skull or other areas of the body. Most lesions require coverage with a scalp flap, though only observation or split-thickness skin grafts may be adequate for smaller lesions. Four cases have been presented, representing a spectrum of therapeutic requirements from simple observation to emergency intervention to control life-threatening hemorrhage. The case of aplasia cutis congenita of the upper arm may represent a persistence of prenatal focal ischemia that has proved to be resistant to numerous attempts of split-thickness skin grafting.
mesh_terms: D001132:Arm / Q000002:abnormalities / Q000601:surgery; D002675:Child, Preschool; D005500:Follow-Up Studies; D006084:Graft Rejection; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011182:Postoperative Care; D012535:Scalp / Q000002:abnormalities* / Q000601:surgery; D012868:Skin Abnormalities; D016038:Skin Transplantation; D014182:Transplantation, Autologous; D014945:Wound Healing