title: Patient cooperation: a determinant of perinatal outcome in the pregnant diabetic.
abstract: From 1974 through 1978, 59 insulin-dependent diabetic patients were treated in a university-affiliated general hospital. They were managed primarily as outpatients with hospitalization for regaining glucose control and/or in the treatment of obstetric complications. In 1976 a special clinic for pregnant diabetic patients was established. The 26 patients treated during the clinic's first two years are compared to 33 treated in the preceding 2 1/2 years. The significant difference between the two groups was the improvement in the number of patients whose cooperation was good, 67% to 85% (p less than 0.05), and the reduction of perinatal morbidity and mortality. The perinatal mortality rate was 18% and 8% in the preclinic group (group I) and the clinic group (group II), respectively. The combined perinatal morbidity and mortality was reduced from 36% to 15%, respectively, in groups I and II (p less than 0.01). A constant rate of 3.2% perinatal mortality was observed in the obstetric population during the study period.
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D005260:Female; D005313:Fetal Death / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology*; D007328:Insulin / Q000627:therapeutic use; D010349:Patient Compliance; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000188:drug therapy / Q000523:psychology*; D011295:Prenatal Care; D013781:Texas
chemical_list: D001786:Blood Glucose; D007328:Insulin