Effects of a mammalian cholesterol biosynthesis inhibitor on adipocyte ultrastructure and metamorphosis in Rhodnius prolixus (Hemiptera).
A potent inhibitor of cholesterol biosynthesis in rodents [BMVA; 5-(4-biphenylyl)-3-methylvaleric acid] inhibits metamorphosis of 4th stage larvae of the blood-sucking bug Rhodnius prolixus.
D000273:Adipose Tissue / Q000187:drug effects / Q000648:ultrastructure*; D000818:Animals; D000924:Anticholesteremic Agents; D001713:Biphenyl Compounds / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects / Q000648:ultrastructure; D008854:Microscopy, Electron; D012239:Rhodnius / Q000187:drug effects / Q000648:ultrastructure*; D014225:Triatominae / Q000648:ultrastructure*
D000924:Anticholesteremic Agents; D001713:Biphenyl Compounds; C026928:5-(4-biphenylyl)-3-methylvaleric acid