Effect of adult thymectomy on immune potentials, endocrine organs and tumor incidence in long-lived mice.
The data presented here indicate that the thymus plays an important role not only in the early ontogenic development of the immune system, but also in the maintenance of the immune potentials throughout the course of life. Moreover, thymic function is closely interrelated with functions of the other endocrine organs.
D000375:Aging; D000818:Animals; D003208:Concanavalin A; D004702:Endocrine Glands / Q000033:anatomy & histology*; D005260:Female; D007109:Immunity; D007157:Immunologic Surveillance; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology*; D051379:Mice; D009929:Organ Size; D010835:Phytohemagglutinins; D013154:Spleen / Q000166:cytology; D013934:Thymectomy
D010835:Phytohemagglutinins; D003208:Concanavalin A