Histopathological evaluation of griseofulvin therapy in lichen planus. A double-blind controlled study.
In a double-blind trial on 44 patients having lichen planus, 500 mg griseofulvin-FP daily for 8 weeks produced significantly better results compared to a placebo. The clinical improvement was accompanied by corresponding histological changes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006118:Griseofulvin / Q000627:therapeutic use*; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D013997:Time Factors
D006118:Griseofulvin