[Ultrastructural characteristics of a monolayer cell culture of the guinea pig pancreatic islet apparatus].
A-, B- and D-insulocytes were revealed when studying the monolayer cell culture of guinea pig pancreatic islands with electron microscope. With an increase in cultivation time (3 days) the cytoplasm ultrastructure in all the cell types changes, the number of secretory granules in B-cells decreases. At later periods (10 days) the signs of secretory cells degeneration and dedifferentiation are observed.
D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D003584:Cytological Techniques; D006168:Guinea Pigs; D007515:Islets of Langerhans / Q000648:ultrastructure*; D008854:Microscopy, Electron / Q000379:methods; D013997:Time Factors
Ul'trastrukturnaia kharakteristika kletok odnosloĭnoĭ kul'tury ostrovkovogo apparata podzheludochnoĭ zhelezy morskikh svinok.