[Nature of antigens antibodies to which are detected in the serum of schizophrenic patients].
The study was conducted by the immune absorption method. The serum activity before and after absorption was studied with the cytotoxic test and the fluorescent antibody method. The studies demonstrated that antibodies, detected in the blood serum of patients and normals differ not only qualitatively but also quantitatively. It was established as well that antibodies detected in normals may be completely absorbed by the brain and thymus of mice or by similar human tissues. In absorption of antibodies in patients by tissues of mice, the activity of the sera entirely disappears. On the contrary, the brain tissue and human thymocytes only insignificantly decrease the serum titres in patients.
D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D001921:Brain / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D005455:Fluorescent Antibody Technique; D006801:Humans; D007163:Immunosorbent Techniques; D051379:Mice; D008808:Mice, Inbred CBA / Q000276:immunology; D012559:Schizophrenia / Q000276:immunology*; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
D001323:Autoantibodies
K voprosu o antigenov, antitela k kotorym obnaruzhivaiutsia v syvorotke krovi bol'nykh shizofrenieĭ.