[Treatment of experimental herpetic keratitis in rabbits with acycloguanosine (author's transl)].
The antiviral activity of a new antiherpetic compound called acycloguanosine was compared to the activity of 0.12 per cent idoxuridine against a superficial herpes simplex keratitis in the rabbit, using a multiple microinoculation technique. The results of the acycloguanosine group were better than the other group. No toxic side effects could be detected by slitlamp examination.
D000212:Acyclovir; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D005260:Female; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D007065:Idoxuridine / Q000627:therapeutic use; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D011817:Rabbits
D000998:Antiviral Agents; D006147:Guanine; D007065:Idoxuridine; D000212:Acyclovir
Traitement de la kératite herpétique expérimentale du lapin par l'acycloguanosine.