The objective evaluation of dysmenorrhea therapy.
Past attempts to obtain objective evaluation of dysmenorrhea therapy have been severly limited by the lack of accurate, reliable intrauterine pressure data. The development of the catheter-tip microtransducer has made accurate, error- and artifact-free intrauterine pressure recording a reality. This information has made assessment of uterine effects of drug therapy feasible. The combination of this type of information with the use of mathematical processing of data has finally made truly objective assessment attainable. A description of the current technique and the findings made possible by its use are presented.
D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004412:Dysmenorrhea / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008528:Mefenamic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D010919:Placebos; D011312:Pressure; D014160:Transducers, Pressure; D014590:Uterine Contraction / Q000187:drug effects; D014599:Uterus / Q000503:physiopathology
D010919:Placebos; D008528:Mefenamic Acid