[Reaction between myasthenia patients' sera and the antigenic structure of the surface of thymic lymphocytes of healthy subjects and myasthenia gravis patients].
It has been established that sera from myasthenia patients contain in 42% of cases IgG antibodies to the point antigenic structure on the lymphocyte surface of the human thymus, spleen and lymph nodes. This antigenic structure is less pronounced on the lymphocytes from the thymus of normal subjects as compared with lymphocytes from the spleen and lymph nodes. On the contrary, the thymocytes from myasthenia patients show an elevated content of the antigen in question and do not differ in this respect from lymphocytes of the peripheral lymphoid organs of normal man.
D000293:Adolescent; D000328:Adult; D000937:Antigen-Antibody Reactions; D000954:Antigens, Surface / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera / Q000276:immunology*; D008198:Lymph Nodes; D009157:Myasthenia Gravis / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000196:embryology / Q000276:immunology
D000954:Antigens, Surface; D007106:Immune Sera
Reaktsiia syvorotok bol'nykh miastenieĭ s antigennoĭ strukturoĭ poverkhnosti limfotsitov timusa zdorovykh liudeĭ i bol'nykh miastenieĭ gravis.