Peptide uptake in Candida albicans.
Transport of radioactively labelled peptides has been used to characterize a common transport system for di- and tripeptides in Candida albicans. This permease is energy-dependent and has a requirement for L-amino acid residues, an alpha-linkage between residues and a free amino terminus. Transport was followed by the accumulation inside the cell of intact peptides and component amino acids. After transport of glycyl-[U-14C]phenylalanine the radioactive material was accumulated inside the cell and subsequently leaked into the medium under certain conditions.
D000596:Amino Acids / Q000378:metabolism; D001693:Biological Transport, Active; D002176:Candida albicans / Q000201:enzymology / Q000378:metabolism*; D004151:Dipeptides / Q000378:metabolism; D007700:Kinetics; D026901:Membrane Transport Proteins / Q000378:metabolism; D010455:Peptides / Q000378:metabolism*
D000596:Amino Acids; D004151:Dipeptides; D026901:Membrane Transport Proteins; D010455:Peptides