Kernicterus 1980: problems and practices viewed from the perspective of the practicing clinician.
An understanding of the pathophysiologic factors causing kernicterus, the determination of infants at greatest risk for developing kernicterus, even the cornerstone of therapy for kernicterus--controlling the bilirubin level--are in a current (and continuous) state of revision. These changing concepts are discussed in light of recent research.
D001663:Bilirubin / Q000378:metabolism; D001927:Brain Diseases / Q000209:etiology; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007647:Kernicterus / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D010634:Phenobarbital / Q000627:therapeutic use; D010789:Phototherapy
D001663:Bilirubin; D010634:Phenobarbital