[Changes in methotrexate pharmacokinetics by inclusion in liposomes and the different effects on experimentally induced tumors].
Encapsulation of methotrexate in liposomes does not only alter--as is generally known--the pharmacokinetics of the drug, but reduces the growth of some experimentally induced tumors in rats.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D008081:Liposomes / Q000008:administration & dosage*; D008727:Methotrexate / Q000097:blood / Q000494:pharmacology*; D051379:Mice
D008081:Liposomes; D008727:Methotrexate
Anderung der Pharmakokinetik von Methotrexat durch Einschluss in Liposomen und die unterschiedliche Wirkung auf experimentell induzierte Tumoren.