Cinoxacin for treatment and prevention of recurrent urinary tract infection.
Cinoxacin, an orally administered synthetic antimicrobial agent, is highly effective in the treatment of urinary tract caused by most urinary tract pathogens. Its high prolonged urinary concentration, low incidence of adverse reactions, low fecal concentration, infrequent induction of resistant bacterial strains, and broad antimicrobial spectrum are valuable attributes. Its efficacy for prolonged low-dose preventive therapy of frequently recurring infections adds to this new drug's importance.
D000658:Amoxicillin / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000517:prevention & control; D002937:Cinoxacin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D011724:Pyridazines / Q000627:therapeutic use*; D011897:Random Allocation; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000517:prevention & control
D011724:Pyridazines; D000658:Amoxicillin; D002937:Cinoxacin