[Lethal and mutagenic action of UV light on salmonellae carrying wild or mutant alleles of the Escherichia coli lexA-gene].
To elucidate the reasons for the absence of UV-mutability in Salmonella typhimurium, the lexA gene of Escherichia coli has been transduced by phage P1 into S. typhimurium. The functioning of lexA+ allele of E. coli in the chromosome of Salmonella failed to cause UV-mutability of the hybrid. The transfer of pKM101 plasmid into the LexA+ hybrid mediates the expressed UV mutability and UV-protective plasmid effect. This plasmid harboured by the LexA hybrid fails to increase UV-resistance and mutability, thus showing the dependence of plasmid mediated effect on LexA+ phenotype.
D000483:Alleles; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes / Q000528:radiation effects*; D009154:Mutation; D010957:Plasmids / Q000528:radiation effects; D012486:Salmonella typhimurium / Q000235:genetics / Q000528:radiation effects*; D014161:Transduction, Genetic / Q000528:radiation effects; D014466:Ultraviolet Rays
Letal'noe i mutagennoe deĭstvie UF-sveta na sal'monelly, nesushchie dikiĭ ili mutantnyĭ alleli lexA-gena kishechnoĭ palochki.