Maternal ethanol consumption and fetal development in the rat: a comparison of ethanol exposure techniques.
Comparison of the polydipsia and liquid diet procedures for ethanol exposure were used in female rats, either before and/or during gestation. Autopsy of the fetuses on day 20 of gestation found a significant weight reduction in the polydipsia-exposed animals that could be attributed to ethanol. No such effect was found in the liquid diet-exposed animals. The data are discussed in relation to the human fetal alcohol syndrome.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004326:Drinking; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D005317:Fetal Growth Retardation / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D051381:Rats; D013997:Time Factors
D000431:Ethanol