A method for multiple intraarterial injections in the allogeneic or isogeneic transplanted rat kidney by use of a long term catheter in the renal artery.
An experimental model using a permanent catheter in the artery of a transplanted rat kidney is presented. The experimental set-up allows selective infusion or injection into the renal circulation of unrestrained non anesthetized rats. It is also possible to make repeated studies of the renal circulation in a rejecting rat kidney transplant. Preliminary investigations and future applications are discussed.
D000818:Animals; D002404:Catheterization; D002408:Catheters, Indwelling; D007269:Injections, Intra-Arterial / Q000379:methods*; D016030:Kidney Transplantation; D008297:Male; D051381:Rats; D011920:Rats, Inbred WF; D012077:Renal Artery; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic