title: The relative accuracy and reliability of histological aging methods.
abstract: Histological aging methods of Kerley and of Ahlqvist and Damsten were applied to bone samples from thirteen individuals of known age at death. Relative accuracy and reliability were determined for six of Kerley's predicting formulas for the femur, fibula and tibia, and his profile method, Ahlqvist and Damsten's femoral predicting formulas, and age determined by averaging ages predicted by Kerley's six formulas. Averaging age estimates by Kerley's six formulas (mean regression) was found to produce the overall greatest accuracy and reliability. Dividing the sample into two age groups (13 - 51 and 60 - 102 years) altered the results only slightly. Kerley's femoral intact osteon formula produced the greatest accuracy for individuals in the younger age category, while his fibular osteon fragment formula was most accurate for older ages. Mean regression produced the greatest reliability for all age classes. Based upon both accuracy and reliability, averaging age predictions by Kerley's regression formulas appears to be the method of choice for broad application of histological aging.
mesh_terms: D000293:Adolescent; D000328:Adult; D000365:Age Determination by Skeleton; D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D005269:Femur / Q000033:anatomy & histology; D005360:Fibula / Q000033:anatomy & histology; D005554:Forensic Medicine; D006253:Haversian System / Q000033:anatomy & histology; D006652:Histological Techniques; D006801:Humans; D008297:Male; D008875:Middle Aged; D013977:Tibia / Q000033:anatomy & histology