Gentamicin-resistant Serratia marcescens endophthalmitis.
In a case of metastatic Gram-negative endophthalmitis caused by Serratia marcescens, the bacterial isolate was resistant to gentamicin sulfate and tobramycin but sensitive to amikacin sulfate, a new semisynthetic aminoglycoside approved for systemic use. The importance of antibiotic-resistant S marcescens as a systemic and ocular pathogen is reviewed.
D000583:Amikacin / Q000008:administration & dosage / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001431:Bacteriological Techniques; D004352:Drug Resistance, Microbial; D009877:Endophthalmitis / Q000188:drug therapy* / Q000209:etiology; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007612:Kanamycin / Q000031:analogs & derivatives*; D008875:Middle Aged; D012706:Serratia marcescens / Q000187:drug effects*; D014031:Tobramycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D007612:Kanamycin; D000583:Amikacin; D014031:Tobramycin