Mesenchymal cells from the human embryonic palate are highly responsive to epidermal growth factor.
An established line of mesenchymal cells from the human embryonic palate is highly sensitive to the stimulatory effect of epidermal growth factor on growth, labeled thymidine incorporation, and ornithine decarboxylase activity. The results suggest that epidermal growth factor may play a key role in development of various human embryonic and fetal tissues.
D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D004261:DNA Replication / Q000187:drug effects; D004622:Embryo, Mammalian; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D007700:Kinetics; D009928:Organ Specificity; D009955:Ornithine Decarboxylase / Q000378:metabolism; D010159:Palate / Q000187:drug effects / Q000502:physiology*; D010455:Peptides / Q000494:pharmacology*; D011247:Pregnancy
D007328:Insulin; D010455:Peptides; D004815:Epidermal Growth Factor; D009955:Ornithine Decarboxylase