Insulin-lecithin interaction in non-aqueous solvents and its change after application of a static electric field.
The interaction between dipalmitoyl lecithin and egg lecithin with insulin was studied in a non-aqueous solvent such as dioxane-chloroform (1:1) by dielectric constant measurements and absorption spectra. The electrostatic character of the interaction results from the dielectric measurements and the effect of an external application of a static electric field (F = 30 kV/cm) is apparently related to the strength of such an interaction. The different strength of interaction of insulin with the two types of lecithins results also from experiments with a two-phase system.
D000818:Animals; D002645:Chickens; D002725:Chloroform; D004146:Dioxanes; D004560:Electricity; D007328:Insulin; D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D012997:Solvents; D013053:Spectrophotometry
D004146:Dioxanes; D007328:Insulin; D010713:Phosphatidylcholines; D011663:Pulmonary Surfactants; D012997:Solvents; D002725:Chloroform