[Histologic investigations of PTFE-surface acting for direct tissue contact on implants (author's transl)].
Generally, implants give rise to toxic reactions and favour the formation and propagation of local infections. Adherance of the soft tissue to the implant prevents the development of fluid filled cavities, thus being of particular interest as a prophylactic measure in arresting spread of infections. Teflon cylinders with an etched surface have been investigated by optical and electron microskopic means following subcutane implantation in mice. We were able to demonstrate closed tissue contact. Signs of toxic tissue reactions were completely absent.
D000818:Animals; D001672:Biocompatible Materials; D005549:Foreign-Body Reaction / Q000517:prevention & control*; D051379:Mice; D008854:Microscopy, Electron; D011138:Polytetrafluoroethylene / Q000633:toxicity*; D019736:Prostheses and Implants; D012867:Skin / Q000166:cytology* / Q000276:immunology / Q000648:ultrastructure; D013530:Surgical Wound Infection / Q000517:prevention & control
D001672:Biocompatible Materials; D011138:Polytetrafluoroethylene
Histologische Untersuchung eines PTFE-Oberflächenbelages zur Erreichung eines direkten Gewebskontaktes am Implantat.