Prostaglandins do not modulate the positive chronotropic and inotropic effects of sympathetic nerve stimulation and injected norepinephrine in the isolated blood perfused canine atrium.
D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology; D016275:Atrial Function; D004285:Dogs; D011464:Epoprostenol / Q000494:pharmacology*; D006321:Heart / Q000502:physiology*; D006325:Heart Atria / Q000187:drug effects; D006329:Heart Conduction System / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D007213:Indomethacin / Q000494:pharmacology; D009200:Myocardial Contraction / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology*; D011453:Prostaglandins / Q000494:pharmacology*; D011458:Prostaglandins E / Q000494:pharmacology*; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000502:physiology*
D001095:Arachidonic Acids; D011453:Prostaglandins; D011458:Prostaglandins E; D011464:Epoprostenol; D009638:Norepinephrine; D007213:Indomethacin