Linkage of an acetylenic secosteroid suicide substrate to the active site of delta 5-3-ketosteroid isomerase. Isolation and characterization of a tetrapeptide.
D000596:Amino Acids / Q000032:analysis; D001665:Binding Sites; D004963:Estrenes / Q000494:pharmacology*; D007535:Isomerases / Q000037:antagonists & inhibitors*; D007700:Kinetics; D009842:Oligopeptides / Q000032:analysis; D010446:Peptide Fragments / Q000032:analysis; D010447:Peptide Hydrolases; D011485:Protein Binding; D011549:Pseudomonas / Q000201:enzymology*; D012632:Secosteroids / Q000494:pharmacology*; D013251:Steroid Isomerases / Q000037:antagonists & inhibitors*; D013820:Thermolysin
D000596:Amino Acids; D004963:Estrenes; D009842:Oligopeptides; D010446:Peptide Fragments; D012632:Secosteroids; C024783:5,10-secoestr-5-yne-3,10,17-trione; D010447:Peptide Hydrolases; D013820:Thermolysin; D007535:Isomerases; D013251:Steroid Isomerases; C022660:steroid delta-isomerase