The pH dependence of the mutagenicity of methyl benzimidazol-2-yl carbamate (MBC) towards Aspergillus nidulans (Eidam) Winter and Cladosporium cucumerinum Ellis & Arth.
The ability of methyl benzimidazol-2-yl carbamate (MBC) to induce point mutations to carboxin and MBC resistance in Aspergillus nidulans (Eidam) Winter and Cladosporium cucumerinum Ellis & Arth. was dependent upon the pH value of the agar medium into which it had been incorporated. The relevance of this in relation to testing chemicals for a possible mutagenic activity with microorganisms is discussed.
D000935:Antifungal Agents / Q000378:metabolism / Q000494:pharmacology*; D001233:Aspergillus nidulans / Q000235:genetics; D002963:Cladosporium / Q000235:genetics; D003470:Culture Media / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009153:Mutagens; D009154:Mutation
D000935:Antifungal Agents; D003470:Culture Media; D009153:Mutagens