Chemical, physical, and biologic properties of biosynthetic human insulin.
Human insulin derived via recombinant DNA technology was tested extensively by a complex battery of analytic procedures. This product, which is designated biosynthetic human insulin, was found to be chemically, physically, and immunologically equivalent to pancreatic human insulin and biologically equivalent to both pancreatic human insulin and purified pork insulin.
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D003460:Crystallization; D004274:DNA, Recombinant; D006801:Humans; D007328:Insulin / Q000096:biosynthesis; D007515:Islets of Langerhans / Q000032:analysis; D011487:Protein Conformation; D011863:Radioimmunoassay; D013056:Spectrophotometry, Ultraviolet; D013552:Swine
D000596:Amino Acids; D004274:DNA, Recombinant; D007328:Insulin