Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE.
A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.
D000328:Adult; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid / Q000276:immunology*; D000918:Antibody Specificity; D003429:Cross Reactions; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007163:Immunosorbent Techniques; D008457:Measles / Q000134:cerebrospinal fluid / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D010455:Peptides / Q000276:immunology*; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D010455:Peptides