title: Effect of systemic indomethacin on corneal graft survival in rabbits.
abstract: We investigated the effect of systemic indomethacin on corneal graft survival in rabbits. Two weeks following corneal transplants, skin grafts were exchanged between donor-recipient pairs. Indomethacin was started one day prior to transplant and was continued for the duration of the study. Mean graft survival was twice as long in the indomethacin-treated group (P less than 0.001) than in the untreated rabbits.
mesh_terms: D000818:Animals; D016039:Corneal Transplantation; D006085:Graft Survival / Q000187:drug effects*; D007213:Indomethacin / Q000494:pharmacology*; D011817:Rabbits; D016038:Skin Transplantation; D014184:Transplantation, Homologous
chemical_list: D007213:Indomethacin