title: Protein synthesis results in guanosine-5'-diphosphate-3'-diphosphate synthesis in Escherichia coli minicells.
abstract: Minicells of Escherichia coli DS410 synthesized guanosine-5'-diphosphate-3'-diphosphate and guanosine-5'-triphosphate-3'-diphosphate when synthesizing proteins in response to phage T7 infection. The guanosine-5'-diphosphate-3'-diphosphate synthesis was found to be relA+ dependent and inhibited by chloramphenicol.
mesh_terms: D004926:Escherichia coli / Q000235:genetics* / Q000648:ultrastructure; D005786:Gene Expression Regulation; D006150:Guanine Nucleotides / Q000096:biosynthesis*; D006159:Guanosine Tetraphosphate / Q000096:biosynthesis*; D010957:Plasmids; D014176:Protein Biosynthesis; D012343:RNA, Transfer / Q000378:metabolism; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism
chemical_list: D006150:Guanine Nucleotides; D012346:RNA, Transfer, Amino Acyl; D006159:Guanosine Tetraphosphate; D012343:RNA, Transfer