title: Surgical management of Peyronie's disease.
abstract: Various forms of treatment have been advocated for Peyronie's disease but none has been entirely satisfactory. Recent reports in the literature indicate that surgical management consisting of excision and dermal grafting may not be the perfect cure suggested in the original report of Devine and Horton. The authors therefore review their experience in the use of the Devine-Horton technique emphasizing factors thought to be important for success. These include careful selection of patients for operation (patients should be potent, have undergone at least 6 months of conservative treatment, have non-inflammatory painless disease and a resectable localized fibrotic plaque), use of a circumferential incision to allow adequate operative exposure and use of a dermal graft 25% larger than the defect.
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D010411:Penile Induration / Q000188:drug therapy / Q000601:surgery*; D016038:Skin Transplantation; D014182:Transplantation, Autologous; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D014810:Vitamin E