Selective inhibition of ribonucleotide reductase by the monofunctional alkylating agent 5(1-aziridinyl)-2,4-dinitrobenzamide (CB 1954).
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D001388:Aziridines / Q000494:pharmacology*; D001389:Azirines / Q000494:pharmacology*; D002279:Carcinoma 256, Walker / Q000378:metabolism; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D051381:Rats; D012264:Ribonucleotide Reductases / Q000037:antagonists & inhibitors*; D013936:Thymidine / Q000378:metabolism
D000970:Antineoplastic Agents; D001388:Aziridines; D001389:Azirines; D004247:DNA; D012264:Ribonucleotide Reductases; D004259:DNA-Directed DNA Polymerase; D013936:Thymidine