[Experimental infection by "Salmonella typhi-murium": protective role of homologous ribosomal extracts in calves (author's transl)].
Eleven calves, 6 months old, vaccinated or not, have been infected experimentally with 10(7) Salmonella typhi-murium, administered by oral route. The control calves had a serious illness, characterized by a severe diarrhoea, hepatic and renal symptoms and a heavy infestation of the main organs. The other five calves, which were orally and subcutaneously vaccinated with ribosomal extracts of S. typhi-murium and S. dublin showed only a moderate alteration of their health while biochemical disorders at the level of liver and kidneys disappeared. However, salmonella were found in mesenteric lymph nodes, but in much lower amounts than in controls.
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D002462:Cell Membrane / Q000276:immunology; D007711:Klebsiella pneumoniae / Q000276:immunology; D011509:Proteoglycans / Q000276:immunology; D012270:Ribosomes / Q000276:immunology*; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D012486:Salmonella typhimurium; D014611:Vaccination
D011509:Proteoglycans
Etude chez le veau, de l'infection expérimentale par Salmonella typhi-murium: rôle protecteur d'extraits ribosomaux homologues.