[Study of immunosuppressive effect of measles virus. In vitro effect of the leukocyte migration inhibition test (author's transl)].
The effects of the influence of the measles virus, further-attenuated measles virus, autoclaved measles virus, mumps virus and polio virus were investigated on the direct leukocyte migration inhibition test by agarose-droplet method using purified protein derivative as the antigen. It was found that the measles virus either inhibited the production of the leukocyte migration inhibition factor or inhibited the effect thereof. From this discovery, the mechanism of the suppression of delayed type hypersensitivity by measles virus was discussed.
D000818:Animals; D002464:Cell Migration Inhibition; D006168:Guinea Pigs; D006801:Humans; D007165:Immunosuppression Therapy; D066298:In Vitro Techniques; D007961:Leukocyte Migration-Inhibitory Factors / Q000096:biosynthesis; D007962:Leukocytes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology; D008459:Measles virus / Q000276:immunology*
D007961:Leukocyte Migration-Inhibitory Factors