[Distribution of a cross-reacting antigen common to group A streptococcal polysaccharide and multilayer squamous epithelium in different human organs].
Indirect immunofluorescence with the use of antibodies) to group A streptococcal polysaccharide (A-polysaccharide has shown cross-reacting antigen (CRA) common for A-polysaccharide and the squamous epithelium to be localized, apart from the skin and thymus, in basal layer cells of oral mucosa epithelium, esophagus, inferior portion of the rectum, in salivary and mammary ducts. These tissue carriers of CRA are united by common ectodermal origin. The evidence obtained may be of use in the devising of a method for differential diagnosis of tumors of different genesis. In the course of organogenesis CRA appears early in the monolayer embryonic epithelium. The data presented correlate with those obtained before during study of animal tissues.
D000293:Adolescent; D000328:Adult; D000941:Antigens / Q000032:analysis*; D002648:Child; D003429:Cross Reactions; D004475:Ectoderm / Q000276:immunology; D004848:Epithelium / Q000276:immunology*; D005333:Fetus / Q000276:immunology; D006801:Humans; D009928:Organ Specificity; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013297:Streptococcus pyogenes / Q000276:immunology*; D014018:Tissue Distribution
D000941:Antigens; D011135:Polysaccharides, Bacterial
Rasprostranenie v razlichnykh organakh cheloveka perekrestno reagiruiushchego antigena, obshchego dlia polisakharida streptokokka gruppy A i mnogosloĭnogo ploskogo épiteliia.