Use of saralasin to detect renovascular hypertension in childhood.
Current methods to evaluate renovascular hypertension in the pediatric population often requires a general anesthetic. Saralasin, an angiotensin II competitive inhibitor, is a safe, noninvasive technique which can be utilized at the bedside in a salt-depleted child off antihypertensive medication. Two illustrative cases are presented.
D000450:Aldosterone / Q000097:blood; D000804:Angiotensin II / Q000031:analogs & derivatives*; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D006801:Humans; D006977:Hypertension, Renal / Q000175:diagnosis*; D006978:Hypertension, Renovascular / Q000175:diagnosis*; D007263:Infusions, Parenteral; D008297:Male; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging; D012083:Renin / Q000097:blood; D012504:Saralasin / Q000008:administration & dosage
D000804:Angiotensin II; D000450:Aldosterone; D012083:Renin; D012504:Saralasin