Carcinogenicity and mutagenicity of solvents. I. Glycidyl ethers, dioxane, nitroalkanes, dimethylformamide and allyl derivatives.
The carcinogenicity and/or mutagenicity as well as structural features and relationships of the glycidylethers (principally phenyl-, butyl-, allyl-, and isopropyl-), dioxane, nitroalkanes (nitro methane, ethane and propane), dimethylformamide and allyl derivatives (chloride, alcohol and amine) were examined. Additionally, considerations of the production, use patterns, estimated populations at risk, TLV's and metabolism of the above agents were discussed.
D000498:Allyl Compounds / Q000633:toxicity; D000818:Animals; D002273:Carcinogens; D004126:Dimethylformamide / Q000633:toxicity; D004146:Dioxanes / Q000633:toxicity; D004852:Epoxy Compounds / Q000633:toxicity; D009153:Mutagens; D009574:Nitro Compounds / Q000633:toxicity; D012997:Solvents / Q000633:toxicity*
D000498:Allyl Compounds; D002273:Carcinogens; D004146:Dioxanes; D004852:Epoxy Compounds; D009153:Mutagens; D009574:Nitro Compounds; D012997:Solvents; C020344:glycidyl ethers; D004126:Dimethylformamide; C025223:1,4-dioxane