title: Comparison of histologic subtypes of multiple biopsies of malignant lymphoma.
abstract: This is a retrospective study of 163 patients with Hodgkin disease and 364 patients with other lymphomas who were admitted to one Cancer Hospital (1940--1971). All the histological slides were reviewed and reclassified by one pathologist. In patients who had multiple and sequential biopsies (16 with Hodgkin disease and 97 with non-Hodgkin lymphomas), the histological subtypes remained the same in over 60% of the cases. When changes did occur, the neoplasms progressed toward histologically more malignant forms.
mesh_terms: D001706:Biopsy; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D012189:Retrospective Studies