Karyotype analysis of leukocytes of gray collie (cyclic neutropenia)-normal bone marrow transplant chimeras six years after transplantation.
Karyotype analysis was made on the leukocytes of 2 gray Collie (cyclic neutropenia)-normal bone marrow transplant chimeras transplanted 6 years previously to correct cyclic neutropenia of the gray Collie syndrome. In a male-to-female transplant chimera, all of the to metaphase spreads showed the karyotype of male donor origin. In this and the male-to-male chimera, the morphology of all chromosomes examined showed no gross anomalies or breaks which might be of recipient origin.
D000380:Agranulocytosis / Q000662:veterinary*; D000818:Animals; D016026:Bone Marrow Transplantation; D002678:Chimera; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs / Q000235:genetics*; D005260:Female; D007621:Karyotyping; D007962:Leukocytes / Q000166:cytology*; D008297:Male; D009503:Neutropenia / Q000235:genetics / Q000662:veterinary*; D014184:Transplantation, Homologous