Juvenile osteochondritis dissecans of the knee: etiology.
Of 73 patients in whom 122 lesions of osteochondritis dissecans of the knee developed, nearly half had multiple lesions and 30% were of short stature. Endogenous and exogenous traumas play a minor role in the etiology of this disorder. Over half of the children with a history of trauma had bilateral and symmetrical lesions. Constitutional factors, such as hereditary predisposition, endocrine dysfunction, collagen and epiphyseal abnormalities, are frequently associated with juvenile osteochondritis dissecans of the knee.
D000293:Adolescent; D004838:Epiphyses / Q000002:abnormalities; D005260:Female; D006801:Humans; D007511:Ischemia / Q000150:complications; D007717:Knee / Q000002:abnormalities / Q000098:blood supply; D007718:Knee Injuries / Q000150:complications; D008297:Male; D010007:Osteochondritis / Q000209:etiology* / Q000235:genetics / Q000378:metabolism