Membrane:buffer partition coefficient for ethanol in dimyristoylphosphatidylcholine.
Phase transitions of dimyristoylphosphatidylcholine (DMPC) are followed using optical density measurements, as a function of aqueous ethanol concentration. The shift of the phase transition to lower temperatures is interpreted in terms of the thermodynamics of freezing point depressions. This analysis provides a partition coefficient of ethanol into DMPC of 0.07 liter of solution/kg membrane or 2.64 moles of solvent/mole of DMPC.
D002021:Buffers; D004134:Dimyristoylphosphatidylcholine; D000431:Ethanol; D008081:Liposomes; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D012995:Solubility; D013696:Temperature; D013816:Thermodynamics
D002021:Buffers; D008081:Liposomes; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D000431:Ethanol; D004134:Dimyristoylphosphatidylcholine