title: [Measurement of plasma 1,25 dihydrovitamin D. Normal and pathological values in adults (author's transl)].
abstract: Plasma levels of 1,25 dihydrovitamin D (1,25 (OH)2D) were measured in normal subjects and in patients with various diseases, using a radiocompetition method. Mean values of 89 +/- 58 pmol/l (1 s.d.) were found in normal adults, irrespective of sex. Plasma 1,25 (OH)2D values were high in 12/31 patients with lithiasis and hypercalciuria, in 1/7 patients with lithiasis and normal calciuria and in 2/4 patients with idiopathic parathyroid adenoma; they were normal in 2 patients with essential hypoparathyroidism. 1,25(OH)2D was undetectable in 5 patients with chronic renal failure, low in 7 and normal in 4. Following successful kidney transplantation (serum creatinine less than 120 mumol/l) one-half of the patients had normal values and the other half high values.
mesh_terms: D002117:Calcitriol; D002137:Calculi / Q000097:blood; D004100:Dihydroxycholecalciferols / Q000097:blood*; D004872:Ergocalciferols / Q000031:analogs & derivatives* / Q000097:blood; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood*; D007676:Kidney Failure, Chronic / Q000097:blood; D016030:Kidney Transplantation; D008297:Male; D010279:Parathyroid Diseases / Q000097:blood; D011184:Postoperative Period; D012016:Reference Values
chemical_list: D004100:Dihydroxycholecalciferols; D004872:Ergocalciferols; D006887:Hydroxycholecalciferols; C003564:1,25-dihydroxyergocalciferol; D002117:Calcitriol
vernacular_title: Dosage plasmatique de la 1,25 dihydroxyvitamine D. Valeurs normales et pathologiques chex l'adulte.