title: Comparison of a microbicidal povidone-iodine gel and a placebo gel as catheter lubricants.
abstract: A comparison of povidone-iodine to a placebo gel as urinary catheter lubricants focused on the effects of urethral bacterial counts and on patient comfort. The 50 patients were divided into 2 parallel groups in a single blind study. Both lubricants lowered the bacterial counts, with the reduction achieved by povidone-iodine gel significantly greater than the reduction associated with the placebo (p less than 0.02). The numbers of patients experiencing discomfort from the 2 preparations did not differ nor was there any difference in the degree of discomfort, which was minimal for both groups. No other adverse side effects were reported for either lubricant.
mesh_terms: D000328:Adult; D000368:Aged; D000892:Anti-Infective Agents, Urinary; D002404:Catheterization / Q000379:methods*; D002986:Clinical Trials as Topic; D005782:Gels; D006801:Humans; D008153:Lubrication; D008297:Male; D008875:Middle Aged; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage* / Q000009:adverse effects; D013210:Staphylococcus / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects
chemical_list: D000892:Anti-Infective Agents, Urinary; D005782:Gels; D011206:Povidone-Iodine; D011205:Povidone