title: [Alcoholism and depression (author's transl)].
abstract: Alcoholism and depression have always been in intricated. A lot of studies try presently to precise this relation:--Clinical studies about episodic alcoholism.--Genetical studies showing a debatable relation between alcoholism and unipolar depression.--Biological studies essentialy attesting a depressive action of ethanol among the serotoninergic system: ethanol would deviate the serotonin metabolism. Likewise it would induce a depletion of catecholamines in the brain. More, biochemical researches point out an inheritance of ethanol preference which would be correlated with a decrease of the brain level of serotonin. Is is a genetical transmission of alcoholism: these perturbations could manifest themselves by the ethanol dependence, or by depressive trends?
mesh_terms: D000437:Alcoholism / Q000150:complications* / Q000235:genetics / Q000378:metabolism; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology; D001923:Brain Chemistry; D002395:Catecholamines / Q000502:physiology; D003863:Depression / Q000150:complications* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D012701:Serotonin / Q000502:physiology
chemical_list: D000928:Antidepressive Agents; D002395:Catecholamines; D012701:Serotonin
vernacular_title: Alcoolisme et dépression.