[Renocortical oxygen supply after kidney transplantation. Renocortical oxygen supply and kidney circulation after autologous kidney transplantation in the dog; its value for human kidney transplantation].
Determination of the viability of a transplanted kidney is still an unsolved problem. Apart from immunological effects hemodynamic and microcirculatory changes in the kidney are important. Thus in 39 mongrel dogs renal floow flow (electromagnetic and local renocortical oxygen supply) and microcirculation (by meaning local tissue pO2) were determined before nephrectomy, immediately after revascularization and before sacrification in experiments with autologous transplantation. Whole kidney blood flow decreased by 30-40%. Measurements of tissue pO2 revealed distinct changes in renocortical oxygen supply. Graft function concomitantly was reduced. Hypotension during revascularization is followed by a strong decrease in renal blood flow and renocortical oxygen supply. Even short periods of hypotension should be avoided.
D000818:Animals; D004285:Dogs; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D007672:Kidney Cortex / Q000378:metabolism*; D016030:Kidney Transplantation; D009929:Organ Size; D010101:Oxygen Consumption
Renokortikale Sauerstoffversorgung nach Nierentransplantation. Renokortikale Sauerstoffversorgung und Nierendurchblutung nach autologer Nierentransplantation beim Hund; ihre Bedeutung für die Nierentransplantation beim Menschen.