Early pregnancy factor: its role in mammalian reproduction--research review.
An immunosuppressive early pregnancy factor associated with mammalian reproduction is currently attracting considerable interest. Research into its detection, site of production, distribution, immunosuppressive property, characterization, and application is in progress in a number of laboratories. This review aims to crystallize the current research findings and to identify significant areas for further investigation and application.
D000822:Animal Husbandry; D000818:Animals; D018835:Chaperonin 10; D005260:Female; D005306:Fertilization; D006801:Humans; D007108:Immune Tolerance; D007166:Immunosuppressive Agents / Q000032:analysis / Q000276:immunology / Q000502:physiology*; D007434:Intrauterine Devices; D010455:Peptides; D011247:Pregnancy; D011257:Pregnancy Proteins; D011270:Pregnancy, Animal; D012397:Rosette Formation; D013491:Suppressor Factors, Immunologic
D018835:Chaperonin 10; D007166:Immunosuppressive Agents; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor