title: Heterozygosity and segregation in Candida albicans.
abstract: Strain FC18 of the pathogenic yeast Candida albicans is heterozygous at a gene required for synthesis of methionine and cysteine, and yields auxotrophic derivatives by induced mitotic segregation. Derivatives of FC18 are heterozygous at other genes. Genetic analysis of C. albicans is feasible using induced mitotic recombination.
mesh_terms: D002176:Candida albicans / Q000235:genetics*; D003545:Cysteine / Q000235:genetics*; D005796:Genes; D006580:Genetic Carrier Screening / Q000379:methods*; D008715:Methionine / Q000235:genetics*; D008938:Mitosis; D011995:Recombination, Genetic
chemical_list: D008715:Methionine; D003545:Cysteine