Measles-specific antibodies in sera and cerebrospinal fluids of patients with multiple sclerosis.
Immunoprecipitation methods were used to analyze sera and cerebrospinal fluids from patients with multiple sclerosis for measles virus-specific antibodies. The sera contained antibodies against all virus antigens except the matrix polypeptide. Of the nine cerebrospinal fluids investigated, two contained undetectable levels of measles-specific antibodies, four contained antibodies against the nucleocapsid and another internal antigen, and three contained antibodies against the surface antigens as well as the internal antigens.
D000914:Antibodies, Viral / Q000032:analysis* / Q000134:cerebrospinal fluid; D000956:Antigens, Viral; D002213:Capsid / Q000276:immunology; D006801:Humans; D007158:Immunologic Techniques; D008459:Measles virus / Q000276:immunology*; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000276:immunology*; D014764:Viral Proteins / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral; D014764:Viral Proteins