title: [Mesangial kidney cells: structure and function under normal and pathological conditions].
abstract: A review of the data on the structure and functions of mesangial cells (MC) and mesangial matrix of the kidneys in normal subjects under experimental conditions and in human pathology is presented. An important role of MC in purification of the glomerular filter is emphasized, their participation in regulation of the glomerular blood flow, the possibility of renin production by them and other functions are considered. Most frequent lesions of MC and their importance in the development of glomerular pathology of the kidneys are described. The nature of MC is discussed.
mesh_terms: D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D002463:Cell Membrane Permeability; D005919:Glomerular Filtration Rate; D005921:Glomerulonephritis / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D007678:Kidney Glomerulus / Q000166:cytology* / Q000473:pathology; D012083:Renin / Q000378:metabolism
chemical_list: D012083:Renin
vernacular_title: Mezangial'nye kletki pochki: struktura i funktsiia v norme i patologii.