The role of Candida albicans in the pathogenesis of angular cheilosis.
It was concluded from the results of this study that: 1. The incidence of chronic C. albicans infection is greater than previously believed. 2. Angular cheilosis and denture sore mouth are often found together. The etiology of both lesions is C. albicans. 3. Systemic factors may be responsible for intraoral candidiasis, but they are of secondary importance in the etiology of angular cheilosis. The primary etiologic agent is C. albicans. 4. Nutritional deficiency or reduced vertical dimension of occlusion are contributing factors in the pathogenesis of angular cheilosis, but C. albicans is the agent primarily responsible for the lesions.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002176:Candida albicans / Q000302:isolation & purification; D002180:Candidiasis, Oral / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008047:Lip Diseases / Q000382:microbiology* / Q000473:pathology; D008875:Middle Aged