[Use of the basophil degranulation test and the leukocyte migration inhibition test to characterize mycogenic sensitization].
The results of experiments in using the basophil degranulation test and the leukocyte migration inhibition test for the characterization of mycogenous sensitization are presented. The model of mycogenous sensitization was created in guinea pigs by 3 injections of homogenized Candida albicans cells. Immediate allergic reaction is shown to develop earlier, as indicated by the results of the determination of homocytotropic antibody tites in passive skin anaphylaxis and by the results of the basophil degranulation test, than the appearance of delayed hypersensitivity detected by the leukocyte migration inhibition test.
D000485:Allergens / Q000032:analysis*; D000818:Animals; D001491:Basophils / Q000648:ultrastructure; D002176:Candida albicans / Q000276:immunology*; D003594:Cytoplasmic Granules; D006168:Guinea Pigs; D006967:Hypersensitivity / Q000175:diagnosis / Q000276:immunology*; D007111:Immunity, Cellular; D007518:Isoantibodies / Q000032:analysis; D007961:Leukocyte Migration-Inhibitory Factors / Q000032:analysis; D010323:Passive Cutaneous Anaphylaxis; D012698:Serologic Tests
D000485:Allergens; D007518:Isoantibodies; D007961:Leukocyte Migration-Inhibitory Factors
Ispol'zovanie testa degranuliatsii bazofilov i reaktsii ingibitsii migratsii leĭkotsitov dlia kharakteristiki mikogennoĭ sensibilizatsii.