A critical efficacy test of cambendazole in equids: the use of the geometric means to assess efficacy.
The anthelmintic efficacy of a 44.5% paste formulation of cambendazole was evaluated in a critical trial performed on 5 horses and a donkey. A dosage of 20 mg/kg showed reduction of mean parasite burdens as follows: Strongylinae greater than 99%; Cyathostominae 94%; immature and adult Oxyuris equi 89 and greater than 99%; Probstmayria vivipara greater than 99% and Habronema muscae 97%. Parascaris equorum and Anoplocephala perfoliata were present in small numbers in individual animals only, and while all were removed by treatment, the small numbers did not justify calculation of a percentage efficacy for these 2 parasites.
D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage*; D002159:Cambendazole / Q000008:administration & dosage*; D002986:Clinical Trials as Topic / Q000662:veterinary; D005243:Feces / Q000469:parasitology; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses / Q000469:parasitology; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D009824:Ointments; D010270:Parasite Egg Count; D010527:Perissodactyla / Q000469:parasitology*
D001562:Benzimidazoles; D009824:Ointments; D002159:Cambendazole