title: [Exoprotease biosynthesis by an Actinomyces spheroides culture on a medium with limited carbon, nitrogen and sulfur sources].
abstract: The biosynthesis of exoproteases by Actinomyces spheroides 35 was studied in the conditions of limitation of the growth medium with the source of carbon, nitrogen and sulfur. The absence of these sources from the medium was found to induce the synthesis of exoproteases by the washed mycelium of Actinomyces spheroides. The enzymes were synthesized at a highest rate in the absence of nitrogen and sulfur sources. Protein as a sole source of carbon, nitrogen or sulfur in the medium suppressed rather than induced the biosynthesis of exoproteases by the culture.
mesh_terms: D002244:Carbon / Q000378:metabolism*; D003470:Culture Media; D004790:Enzyme Induction / Q000187:drug effects; D009584:Nitrogen / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D013302:Streptomyces / Q000201:enzymology*; D013455:Sulfur / Q000378:metabolism*
chemical_list: D003470:Culture Media; D013455:Sulfur; D002244:Carbon; D010447:Peptide Hydrolases; D009584:Nitrogen
vernacular_title: Biosintez ékzoproteaz kul'turoĭ Actinomyces spheroides v usloviiakh limitatsii sredy istochnikami ugleroda, azota i sery.