Actions of cholera toxin and the prevention and treatment of cholera.
The drastic intestinal secretion of fluid and electrolytes that is characteristic of cholera is the result of reasonably well understood cellular and biochemical actions of the toxin secreted by Vibrio cholerae. Based on this understanding it is possible to devise new techniques for the treatment and prophylaxis of cholera to complement those based on fluid replacement therapy and sanitation.
D000262:Adenylyl Cyclases / Q000378:metabolism; D002771:Cholera / Q000188:drug therapy / Q000517:prevention & control*; D002772:Cholera Toxin / Q000494:pharmacology; D022121:Cholera Vaccines / Q000627:therapeutic use; D004789:Enzyme Activation / Q000187:drug effects; D005677:G(M1) Ganglioside / Q000378:metabolism; D006801:Humans; D011487:Protein Conformation
D022121:Cholera Vaccines; D005677:G(M1) Ganglioside; D002772:Cholera Toxin; D000262:Adenylyl Cyclases