Metabolic activation of 1-methyl-3-amino-5H-pyrido[4,3-b]indole and several structurally related mutagens.
D000818:Animals; D001711:Biotransformation; D002243:Carbolines / Q000378:metabolism / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA; D007211:Indoles / Q000494:pharmacology*; D008715:Methionine; D008722:Methods; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009152:Mutagenicity Tests; D009153:Mutagens; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D013329:Structure-Activity Relationship
D002243:Carbolines; D007211:Indoles; D009153:Mutagens; D008748:Methylcholanthrene; C019133:3-amino-1-methyl-5H-pyrido(4,3-b)indole; D004247:DNA; D008715:Methionine