[Antigenic translocation of carcinoembryonic antigen in large intestine epithelial cells].
By an indirect Coons test, a carcinoembryonic antigen (CEA) localization was studied in cells of colon mucosa at various stages of human embryonic development, polyps, and in cases of non-tumoral changes. Laboratory investigations have shown that there are several variants of CEA localization in embryogeny, precancerous tissue, and in cells with inflammatory changes. A comparison of the obtained data and forms of antigenic translocation in malignant tissue leads to a conclusion that the antigenic translocation phenomenon is of biological nature, reflecting the degree of changes in the inner structure of cells under various conditions of existence.
D002272:Carcinoembryonic Antigen / Q000032:analysis*; D004622:Embryo, Mammalian / Q000276:immunology; D004848:Epithelium / Q000276:immunology; D005333:Fetus / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007410:Intestinal Diseases / Q000276:immunology; D007413:Intestinal Mucosa / Q000276:immunology; D007417:Intestinal Polyps / Q000276:immunology; D007420:Intestine, Large / Q000276:immunology*
D002272:Carcinoembryonic Antigen
Antigennaia translokatsiia rakovo-émbrional'nogo antigena v épitelial'nykh kletkakh tolstoĭ kishki.