Identification of a cytotoxin produced by Legionella pneumophila.
Culture filtrates of Legionella pneumophila were cytotoxic for Chinese hamster ovary cells. The cytotoxin was found to be methanol soluble, heat stable, and stable from pH 5 through 8.
D000818:Animals; D001419:Bacteria / Q000378:metabolism*; D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D006224:Cricetinae; D003603:Cytotoxins / Q000096:biosynthesis* / Q000494:pharmacology; D005260:Female; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D007877:Legionnaires' Disease / Q000382:microbiology; D010053:Ovary; D010447:Peptide Hydrolases / Q000494:pharmacology
D001427:Bacterial Toxins; D003603:Cytotoxins; D010447:Peptide Hydrolases