[State of the insular apparatus in experimental thyrotoxicosis].
The oral intravenous glucose tolerance tests revealed an increase in the rate of glucose utilization in rabbits fed high thyroidine doses. Hypoglycemia and hypoinsulinemia on fasting stomach, as well as a reduction of insulin reaction to intravenous glucose load were seen in such animals. A fall of insulin secretion in thyrotoxicosis is considered to be a compensatory reaction permitting glucose output from the liver to meet increased tissue demands in the oxidative substrates.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D005947:Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D006980:Hyperthyroidism / Q000378:metabolism*; D007328:Insulin / Q000097:blood / Q000378:metabolism; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats
D001786:Blood Glucose; D007328:Insulin; D005947:Glucose
O sostoianii insuliarnogo apparata pri éksperimental'nom tireotoksikoze.