title: [New class of bacterial translation mutants].
abstract: Two suppressor mutations of phage T4, which specifically suppress different opal mutations in the same phage T4 genome, have been obtained. One of these mutations possessed suppressor activity at 27 degrees C but not at 42 degrees C. It is shown that these suppressor mutations operate on the level of translation and probably localize in one of the genes determining the synthesis of phage T4 tRNA. Two strains of Escherichia coli B which were able to restrict this opal suppressor and did not affect amber or ochra suppressor activity of phage T4, were obtained. Possible mechanism of phage T4 opal suppressor activity and the nature of their restriction in bacterial mutants are discussed.
mesh_terms: D004926:Escherichia coli / Q000235:genetics*; D014176:Protein Biosynthesis; D012343:RNA, Transfer / Q000235:genetics; D013489:Suppression, Genetic; D013604:T-Phages / Q000235:genetics*
chemical_list: D012343:RNA, Transfer
vernacular_title: Novyi klass transliatsionnykh mutantov u bakteriĭ.