The Crithidia luciliae immunofluorescent test for the detection of antibodies to native DNA.
The Crithidia luciliae test was compared with the radioimmunoassay technique for n DNA antibodies on 93 randomly selected sera submitted for antibody testing, and was found to be a highly specific, reproducible and economical test. It appeared to be less sensitive than the radio-immunoassay technique in sera from some of the patients, but analysis of the clinical findings showed that the C. luciliae test correlated better with the clinical assessment of these patients.
D000974:Antibodies, Antinuclear / Q000032:analysis*; D003421:Crithidia / Q000276:immunology*; D004247:DNA / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000175:diagnosis*; D011863:Radioimmunoassay
D000974:Antibodies, Antinuclear; D004247:DNA