Transient hypoglycemia following 25-hydroxycholecalciferol administraton to mice.
A transient hypoglycemia was found 4 hrs after injection of 25-hydroxycholecalciferol (25-HCC) in mice. This was not associated with any significant alteration in the serum insulin concentration, suggesting that the hypoglycemic response is due to extrapancreatic factors. Pretreatment with 25-HCC did not affect the development of alloxan diabetes.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002112:Calcifediol; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D007003:Hypoglycemia / Q000139:chemically induced*; D007328:Insulin / Q000097:blood; D051379:Mice; D008815:Mice, Inbred Strains
D001786:Blood Glucose; D006887:Hydroxycholecalciferols; D007328:Insulin; D002112:Calcifediol