Petite-negative mutants of Saccharomyces cerevisiae.
A series of yeast mutants has been isolated with the inability to grow on fermentable carbon sources whilst growing normally on ethanol media. One of the mutants, namely MC16/206 lacks pyruvate decarboxylase activity and does not grow on glucose at 37 degrees C but grows on both ethanol and glucose at 27 degrees C. In this strain rho- petites are non-viable.
D000429:Alcohol Oxidoreductases / Q000235:genetics; D002262:Carboxy-Lyases / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics; D004734:Energy Metabolism; D005796:Genes; D009154:Mutation; D011767:Pyruvate Decarboxylase / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics*
D004272:DNA, Mitochondrial; D000429:Alcohol Oxidoreductases; D002262:Carboxy-Lyases; D011767:Pyruvate Decarboxylase