Cellular transplantation in the treatment of experimental hepatic failure.
The survival of Lewis rats with D-galactosamine-induced fulminant hepatic failure was prolonged if they were given intraperitoneal injections of single-cell suspensions of liver or bone marrow cells from normal rats. Suspensions of liver cells were also effective in prolonging the survival of rats with ischemia-induced hepatic necrosis. The liver cells did not act by repopulating the recipient liver.
D000818:Animals; D016026:Bone Marrow Transplantation; D004195:Disease Models, Animal; D005688:Galactosamine; D006498:Hepatectomy; D000860:Hypoxia / Q000150:complications; D008099:Liver / Q000166:cytology; D008107:Liver Diseases / Q000628:therapy*; D016031:Liver Transplantation; D009336:Necrosis; D051381:Rats; D014184:Transplantation, Homologous
D005688:Galactosamine