The use of prostaglandins as local antithrombotic agents in microvascular surgery.
The effectiveness of Prostaglandin E2 and Prostacyclin as a local antithrombotic agent in microvascular anastomoses was tested experimentally in a controlled double-blind trial in rats. Prostaglandin E2 was found to be ineffective whereas Prostacyclin was found to be very effective.
D000818:Animals; D011464:Epoprostenol / Q000627:therapeutic use*; D005263:Femoral Artery / Q000601:surgery*; D008866:Microsurgery; D011183:Postoperative Complications / Q000517:prevention & control*; D011453:Prostaglandins / Q000627:therapeutic use*; D011458:Prostaglandins E / Q000627:therapeutic use*; D051381:Rats; D013927:Thrombosis / Q000517:prevention & control*; D013997:Time Factors
D011453:Prostaglandins; D011458:Prostaglandins E; D011464:Epoprostenol