title: Augmentation of cyclopropane fatty acid synthesis under stringent control in Escherichia coli.
abstract: An abrupt increase of cyclopropane fatty acid (CFA) occurred concomitant with a decrease of the corresponding unsaturated fatty acids in CP78 (rel+) of Escherichia coli at the onset of the stationary growth phase, whereas such variations were slight in CP79 (rel-). When the cells were starved for isoleucine, the CFA content increased in CP78 but not in CP79. The rate of 14C-incorporation from [methyl-14C]methionine into CFAs increased in CP78 abut two-fold due to the starvation. The apparent level of CFA synthase also increased due to the starvation. These results that the CFA formation is augmented under stringent control.
mesh_terms: D002453:Cell Cycle; D003521:Cyclopropanes; D004926:Escherichia coli / Q000166:cytology / Q000235:genetics / Q000378:metabolism*; D005227:Fatty Acids / Q000096:biosynthesis*; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D007532:Isoleucine / Q000502:physiology; D008780:Methyltransferases / Q000378:metabolism; D009154:Mutation
chemical_list: D003521:Cyclopropanes; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; C028775:cyclopropane fatty acids; D007532:Isoleucine; D008780:Methyltransferases; C019964:cyclopropane synthetase