title: [Pancreatic B cell peptides: kinetic behaviour and concentrations of proinsulin, insulin and C-peptide in plasma and urine, problems of assay methods, clinical significance and literature review (author's transl)].
abstract: The kinetics and the concentrations of B-cell peptides in plasma and urine are reviewed. Methodical problems in the determination of proinsulin, free and antibody-bound insulin and C-peptide are discussed, together with the possible application of these methods in the control of insulin-dependent diabetics.
mesh_terms: D000595:Amino Acid Sequence; D002096:C-Peptide / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000378:metabolism; D007328:Insulin / Q000378:metabolism* / Q000627:therapeutic use; D007330:Insulin Antibodies / Q000032:analysis; D007515:Islets of Langerhans / Q000378:metabolism*; D007700:Kinetics; D010455:Peptides / Q000378:metabolism*; D011384:Proinsulin / Q000378:metabolism*
chemical_list: D002096:C-Peptide; D007328:Insulin; D007330:Insulin Antibodies; D010455:Peptides; D011384:Proinsulin
vernacular_title: Pankreatische B-Zellen-Peptide: Kinetik und Konzentration von Proinsulin, Insulin und C-Peptid in Plasma und Urin, Probleme der Messmethoden, klinische Aussage und Literaturübersicht.