title: Chymopapain chemonucleolysis. A preliminary report.
abstract: Twenty of 26 consecutive patients with sciatica caused by myelographically proven disc protrusions who were treated by chemonucleolysis with chymopapain made useful recovery. There were no major complications attributable to the procedure. Certain diagnostic and clinical criteria are described which appear to be important in producing a favorable result following chemonucleolysis.
mesh_terms: D000328:Adult; D002917:Chymopapain / Q000009:adverse effects / Q000627:therapeutic use*; D010450:Endopeptidases / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000187:drug effects*; D007405:Intervertebral Disc Displacement / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012585:Sciatica / Q000209:etiology*
chemical_list: D010450:Endopeptidases; D002917:Chymopapain