title: Kernicterus 1980: problems and practices viewed from the perspective of the practicing clinician.
abstract: An understanding of the pathophysiologic factors causing kernicterus, the determination of infants at greatest risk for developing kernicterus, even the cornerstone of therapy for kernicterus--controlling the bilirubin level--are in a current (and continuous) state of revision. These changing concepts are discussed in light of recent research.
mesh_terms: D001663:Bilirubin / Q000378:metabolism; D001927:Brain Diseases / Q000209:etiology; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007647:Kernicterus / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D010634:Phenobarbital / Q000627:therapeutic use; D010789:Phototherapy
chemical_list: D001663:Bilirubin; D010634:Phenobarbital