Altered regulation of the recA gene in Escherichia coli strains carrying a recA-linked suppressor of lexA.
A mutant strain of E. coli displaying altered regulation of the recA gene was isolated as a revertant of a lexA3 recA200 double mutant which showed improved DNA repair and recombination functions. The mutant (alc-24) was located between srl and recA200 and caused synthesis of high levels of recA protein in both lexA+ and lexA3 strains. The possibility that alc-24 defines the regulatory site for recA is discussed.
D001426:Bacterial Proteins / Q000096:biosynthesis*; D004260:DNA Repair; D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D005786:Gene Expression Regulation; D005809:Genes, Regulator; D009154:Mutation; D011938:Rec A Recombinases; D011995:Recombination, Genetic; D013489:Suppression, Genetic; D014466:Ultraviolet Rays
D001426:Bacterial Proteins; D011938:Rec A Recombinases