title: Sterile topical lignocaine jelly in plastic surgery: an assessment of its systemic toxicity.
abstract: Topical local anaesthesia offers an important adjunct to several plastic surgery procedures, provided that it does not cause systemic toxicity or prevent the healing process. Absorption of a sterile topical lignocaine jelly was assessed in patients undergoing treatment of skin graft donor sites, flap donor sites and burns. There was a marked degree of absorption only in patients with thermal burns, in which case it depended on the surface area of the wound; although no toxic effects due to absorption were noted, caution in dosage is advisable. No complications of healing attributable to the preparation used were encountered.
mesh_terms: D000772:Anesthesia, Local; D002056:Burns / Q000628:therapy*; D006801:Humans; D008012:Lidocaine / Q000097:blood / Q000378:metabolism* / Q000652:urine; D016038:Skin Transplantation; D013518:Surgery, Plastic
chemical_list: D008012:Lidocaine