Incidence of R-plasmids in fecal flora of healthy household dogs.
Rectal swabs were taken from healthy household dogs that, insofar as could be determined, had not received antimicrobial drugs. Tetracycline-resistant coliforms comprised 80 to 100% of the total number of coliforms in 61 (65%) of the 94 dogs sampled. The median number of other resistance determinants possessed by these tetracycline-resistant coliforms was 5.1. Of the tetracycline-resistant strains studied, 97% were resistant to streptomycin; 76% were resistant to sulfonamides; 59% were resistant to ampicillin; 59% were resistant to kanamycin/neomycin; and 40% were resistant to chloramphenicol. A total of 64% of the strains was shown to transfer resistance by conjugation or by the aid of the sex factor F. Of the strains transferring resistance, 33% were found to transfer all of their resistance determinants.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002140:California; D003227:Conjugation, Genetic; D004285:Dogs / Q000382:microbiology*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005243:Feces / Q000382:microbiology*; D011815:R Factors; D013752:Tetracycline / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D013752:Tetracycline