title: Yeast viral RNA polymerase is a transcriptase.
abstract: ScV-L is a simple double-stranded RNA virus of yeast, consisting of a 4.8 kilobase pair double-stranded RNA (L) encapsidated in isometric particles composed mainly of one polypeptide (ScV-Pl) of 88,000 daltons. L encodes ScV-Pl. There is a capsid-associated RNA polymerase that synthesizes in vitro predominantly single-stranded RNA. We show that this polymerase activity is a transcriptase, at the least one product of which is the mRNA for ScV-Pl. The transcript, like its template, is uncapped.
mesh_terms: D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D009693:Nucleic Acid Hybridization; D014176:Protein Biosynthesis; D012330:RNA, Double-Stranded / Q000096:biosynthesis; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D013698:Templates, Genetic; D014158:Transcription, Genetic; D014780:Viruses / Q000201:enzymology*
chemical_list: D012330:RNA, Double-Stranded; D012321:DNA-Directed RNA Polymerases