Instillation of steroids in the eye: its effect on lymphocytes in regional lymph nodes and in peripheral blood.
The blastogenic response to mitogens by lymphocytes after topical instillation of steroids was studied in rabbits. The effect on lymphocytes from the local draining lymph nodes and peripheral blood was assessed. There was no effect on the lymphocytes of local draining lymph nodes; however, a decrease in phytohaemagglutinin response occurred in peripheral blood lymphocytes.
D000818:Animals; D001623:Betamethasone / Q000494:pharmacology*; D016039:Corneal Transplantation; D005123:Eye / Q000187:drug effects*; D006084:Graft Rejection; D008198:Lymph Nodes / Q000187:drug effects*; D008213:Lymphocyte Activation / Q000187:drug effects; D011817:Rabbits; D014184:Transplantation, Homologous
D001623:Betamethasone