title: [Interaction of catecholamines and the renin-angiotensin system in regulating sodium reabsorption in the rat kidney].
abstract: It has been established that the catecholamine-induced increase in renin secretion by juxtaglomerular apparatus cells and sodium reabsorption stimulation in the rat kidney are consequent on the excitation of renal beta-adrenoreceptors. Strophanthin K interferes with the renin-secreting action of adrenaline and perverts its activating effect on sodium transport by renal tubules. When given in a dose inhibiting angiotensin II formation and renin-secreting effect of catecholamines, heparin also diminishes their activating effect on tubular sodium transport. It is suggested that the renin-angiotensin system may be directly involved into the mechanism of catecholamine-stimulated sodium reabsorption by the rat kidney.
mesh_terms: D000042:Absorption; D000804:Angiotensin II / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002395:Catecholamines / Q000494:pharmacology*; D066298:In Vitro Techniques; D007606:Juxtaglomerular Apparatus / Q000187:drug effects / Q000502:physiology; D007668:Kidney / Q000187:drug effects* / Q000502:physiology; D008297:Male; D009318:Natriuresis / Q000187:drug effects; D051381:Rats; D012083:Renin / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*; D013268:Stimulation, Chemical
chemical_list: D002395:Catecholamines; D000804:Angiotensin II; D012964:Sodium; D012083:Renin
vernacular_title: Vzaimodeĭstvie katekholaminov i sistemy renin-angiotenzin v reguliatsii reabsorbtsii natriia v pochke krysy.