The ultrastructure of neurilemoma with emphasis on Antoni B tissue.
Ten neurilemomas were studied by electron microscopy. Antoni A and B tissues were identified by light microscopy on semithin sections, and the corresponding areas on adjacent ultrathin sections were studied ultrastructurally. The Antoni B tissue definitely possessed features of degeneration in that the cells showed a detached basal lamina, a disrupted cell membrane, degenerated nuclei, and a significant accumulation of cytoplasmic granules and myelin figures. Added to these was intercellular edema with fibrin. The similarity of the granules in the cells of Antoni B tissue, cells of granular cell tumor, and Schwann cells in wallerian degeneration supports the conclusion that these three are related phenomena.
D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006106:Granulosa Cell Tumor / Q000648:ultrastructure; D006652:Histological Techniques; D006801:Humans; D008853:Microscopy; D008854:Microscopy, Electron; D009442:Neurilemmoma / Q000648:ultrastructure*; D010525:Peripheral Nerves / Q000648:ultrastructure; D012583:Schwann Cells / Q000648:ultrastructure; D014855:Wallerian Degeneration