Faecal excretion of entero-pathogens in a Pakistani family returning to the U.K. after a visit to Rawalpindi.
The family consisted of two parents and five children. While the father remained in Cardiff, the mother and all the children visited Rawalpindi, Pakistan, for 6 weeks to stay with relatives. Travel was by flight from Heathrow airport to Pakistan and by a short road journey to Rawalpindi. Mrs M. - the mother - as a guest, did no cooking on the holiday. The house which they were living in had a piped water supply, thought to be treated. There was no flush toilet but a commode was available and was emptied daily. All the children had gastro-enteritis symptoms for 2-3 days after arrival. Ru M. - a daughter - had the most severe illness and was treated by a local doctor. Diarrhoea in the three girls persisted on return to U.K. A faecal swab from Ru M. showed her to be excreting S. typhi (degraded Vi phage type). She was admitted to hospital. Faecal samples from the remaining members of the family were taken and examined for entero-pathogens. The father, Fa. M., who had not left Cardiff, had negative stools and remained free from infection. All other family members were excreting one or more entero-pathogens, including a Campylobacter sp., three types of Sh. flexneri and one type of Sh. boydii. A subsequent faecal sample revealed that one of the male children, A.M., was excreting S. typhi phage type B2. The two typhoid infections were apparently unconnected.The media used for microbiological diagnosis in this incident are discussed and contrasted with those employed for routine Salmonella examination of environmental samples. The advantages of selenite F in clinical diagnosis are noted.Antibiotic therapy was used for both typhoid cases but was not employed for the Shigella infections. The clinical condition of those involved in this incident might well have failed to arouse suspicion and the question arises whether food handlers returning from holiday in tropical and subtropical areas should have bacterological investigations before going back to their employment.
D000328:Adult; D002169:Campylobacter Infections / Q000175:diagnosis / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003470:Culture Media; D004405:Dysentery, Bacillary / Q000175:diagnosis / Q000235:genetics / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010154:Pakistan / Q000208:ethnology; D012485:Salmonella typhi / Q000302:isolation & purification; D012761:Shigella boydii / Q000302:isolation & purification; D012763:Shigella flexneri / Q000302:isolation & purification; D014435:Typhoid Fever / Q000175:diagnosis* / Q000235:genetics / Q000382:microbiology; D006113:United Kingdom
D003470:Culture Media