title: Cerebrospinal fluid rhinorrhoea in pituitary tumours.
abstract: Three cases of CSF rhinorrhoea due to pituitary tumours are reported and the literature reviewed. The treatment of choice appears to be trans-sphenoidal exploration of the pituitary fossa with insertion of a free muscle graft followed by radiotherapy. The probability of the tumour being a prolactin-secreting adenoma is discussed.
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000532:radiotherapy / Q000601:surgery; D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D001284:Atrophy / Q000150:complications; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology*; D003388:Cranial Fossa, Posterior; D007172:Erectile Dysfunction / Q000209:etiology; D005004:Ethmoid Bone / Q000002:abnormalities; D005260:Female; D005402:Fistula / Q000175:diagnosis; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000637:transplantation; D010911:Pituitary Neoplasms / Q000150:complications* / Q000532:radiotherapy / Q000601:surgery; D011388:Prolactin / Q000097:blood; D014182:Transplantation, Autologous
chemical_list: D011388:Prolactin