Mutagenic activity in foundry air.
Organic, cyclohexane soluble foundry air contaminants were assayed for their mutagenic activity with the Ames test. The samples studied were also analyzed for benzo(a)pyrene (BaP) concentrations by glass capillary gas chromatography. All the samples showed mutagenicity towards the strains Salmonella typhimurium TA 98 and TA 100 after metabolic activation. Correlations between the amount of BaP and the mutagenicity were calculated and then compared to the corresponding dose response correlations of known BaP concentrations.
D000393:Air Pollutants / Q000633:toxicity*; D000395:Air Pollutants, Occupational / Q000032:analysis / Q000633:toxicity*; D001580:Benzopyrenes / Q000032:analysis; D007501:Iron; D008669:Metallurgy; D009153:Mutagens; D012486:Salmonella typhimurium / Q000235:genetics
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D001580:Benzopyrenes; D009153:Mutagens; D007501:Iron