Beta-lactamase production and antibiotic sensitivity pattern in community strains of Staphylococcus aureus.
A study of 193 strains of Staphylococcus aureus with respect to beta-lactamase/penicillinase activity and antibiotic sensitivity pattern is reported. Eighty-eight strains were obtained from clinical material from patients treated by physicians in a suburban community. The remaining strains were obtained from healthy military recruits. In the clinical material nearly three out of four strains were beta-lactamase/penicillinase producing as compared to approximately 50% in the recruit material. Six strains were beta-lactamase positive and fully sensitive to penicillin, judged by the disc diffusion technique. Aspects of these findings are discussed.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001431:Bacteriological Techniques; D006801:Humans; D008826:Microbial Sensitivity Tests; D010405:Penicillinase / Q000096:biosynthesis; D010406:Penicillins / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000201:enzymology*; D001618:beta-Lactamases / Q000096:biosynthesis*
D000900:Anti-Bacterial Agents; D010406:Penicillins; D010405:Penicillinase; D001618:beta-Lactamases