title: [Clinical and experimental study of the hemodynamic effect of gemiton].
abstract: The effect of hemiton (clofelin) on the minute circulation volume, general peripheral resistance to the blood flow, and the mechanisms of the regulation of the vascular neurogenous tonus and heart activity was studied in patients in the clinic and in experiments. It is shown that the hemodynamic effect of the agent depends on the initial parameters of hemodynamics. It is assumed that hemiton influences the capacity of systemic circulation. The expediency of combining hemiton with drugs which reduce the minute circulation volume is discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001810:Blood Volume / Q000187:drug effects; D002415:Cats; D002986:Clinical Trials as Topic; D003000:Clonidine / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006321:Heart / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D003000:Clonidine
vernacular_title: Kliniko-éksperimental'noe izuchenie gemodinamicheskogo éffekta gemitona.