The role of vitamin D metabolites in the osteomalacia of renal disease.
Osteomalacia is commonly found in patients with severe renal impairment. Its aetiology is multifactional and not simply due to deficient production of active metabolites of vitamin D. Decreased availability of calcium and phosphate and the accumulation of aluminium is some dialysis-treated patients are also important aetiological factors. The treatment of osteomalacia depends, in part, upon its accurate diagnosis, and identifying and reversing the underlying cause.
D002118:Calcium / Q000378:metabolism; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000150:complications; D010018:Osteomalacia / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D010710:Phosphates / Q000378:metabolism; D014131:Trace Elements / Q000378:metabolism; D014807:Vitamin D / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis
D010710:Phosphates; D014131:Trace Elements; D014874:Water Pollutants, Chemical; D014807:Vitamin D; D002118:Calcium