Cerebral blindness and oculomotor nerve palsies in toxoplasmosis.
We studied the clinicopathologic and neuro-ophthalmic manifestations of central nervous system toxoplasmosis in two patients who were being treated with immunosuppressive chemotherapy, one for renal transplantation and the other for systemic lupus erythematosis. Both pateints had oculomotor nerve palsies and later developed visual loss from cerebral involvement. Multifocal central nervous system toxoplasmosis appeared as a complication of their systemic diseases.
D000328:Adult; D001766:Blindness / Q000209:etiology*; D002493:Central Nervous System Diseases / Q000150:complications*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D014123:Toxoplasmosis / Q000150:complications*; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents