title: Thyrotropes in the pituitary are target cells for 1,25 dihydroxy vitamin D3.
abstract: In the anterior pituitary of the rat, target cells of 1,25 (OH)2 vitamin D3 are identified as those that secrete thyroid stimulating hormone by means of a combined technique of thaw-mount autoradiography and immunohistochemistry. The results for the first time provide evidence that suggests a central effect of 1,25 (OH)2 vitamin D3 on the modulation of thyrotropin secretion in a manner similar to that of other steroid hormones at the level of the pituitary.
mesh_terms: D000818:Animals; D001345:Autoradiography; D004100:Dihydroxycholecalciferols / Q000494:pharmacology*; D006651:Histocytochemistry; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D007158:Immunologic Techniques; D008297:Male; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D013972:Thyrotropin / Q000378:metabolism*
chemical_list: D004100:Dihydroxycholecalciferols; D006887:Hydroxycholecalciferols; D013972:Thyrotropin