[In vivo interactions of Rubella virus with peritoneal macrophages in immunized and non immunized rats].
The pathogenicity of rubella virus for macrophages of immune and non-immune rats was studied using not a natural route of inoculation and studying the sequence of morphologic changes in cells as well as virus growth in the peritoneal cavity, the development of viremia and the neutralizing antibody response against the infectious agent. Non-immune rats evidenced a possible development of cell immunity in the course of the process. Immune rats had acquired a cell immunity in addition to a specific secondary response manifested early at the beginning of infection.
D000818:Animals; D007111:Immunity, Cellular; D007114:Immunization; D008264:Macrophages / Q000276:immunology*; D010529:Peritoneal Cavity / Q000276:immunology*; D051381:Rats; D012412:Rubella virus / Q000276:immunology*; D014779:Virus Replication
Estudio in vivo de la interacción del virus de la rubéola con macrófagos peritoneales en ratas inmunizadas y no inmunizadas.