Clinical toxicology of clotrimazole when administered vaginally.
Clotrimazole, a tritylimidazole and a new antimicrobial agent, produced itching and irritation of the vulva and vaginal area in less than 1% of the population (N = 131) studied. No abdominal cramps, headache or lightheadedness, nausea, vomiting, and diarrhea were observed when 200 mg of clotrimazole was inserted deep in the vagina for several days.
D002177:Candidiasis / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003022:Clotrimazole / Q000008:administration & dosage / Q000009:adverse effects / Q000633:toxicity*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000633:toxicity*; D014621:Vagina / Q000187:drug effects*; D014627:Vaginitis / Q000188:drug therapy
D007093:Imidazoles; D003022:Clotrimazole