title: Early pregnancy factor: its role in mammalian reproduction--research review.
abstract: An immunosuppressive early pregnancy factor associated with mammalian reproduction is currently attracting considerable interest. Research into its detection, site of production, distribution, immunosuppressive property, characterization, and application is in progress in a number of laboratories. This review aims to crystallize the current research findings and to identify significant areas for further investigation and application.
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D018835:Chaperonin 10; D005260:Female; D005306:Fertilization; D006801:Humans; D007108:Immune Tolerance; D007166:Immunosuppressive Agents / Q000032:analysis / Q000276:immunology / Q000502:physiology*; D007434:Intrauterine Devices; D010455:Peptides; D011247:Pregnancy; D011257:Pregnancy Proteins; D011270:Pregnancy, Animal; D012397:Rosette Formation; D013491:Suppressor Factors, Immunologic
chemical_list: D018835:Chaperonin 10; D007166:Immunosuppressive Agents; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor