title: [Use of the radial hemolysis method for determining influenza virus antibodies in human sera].
abstract: Radial hemolysis was used for detection of influenza virus antibody in sera from children and adults in various epidemic outbreaks of 1977-1979. RH is highly sensitive, and the presence of inhibitors does not affect the titration results. The results of RH correlate well with those of the HI and CF tests. The 7S immunoglobulins were active in RH, 19S produced no hemolysis zone. In sera from children under 3 years no correlation between antibody titers by H1 and RH tests was observed in the acute period of the disease but it appeared within 2-3 weeks.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis*; D003168:Complement Fixation Tests / Q000379:methods; D006385:Hemagglutination Inhibition Tests / Q000379:methods; D006462:Hemolytic Plaque Technique; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000276:immunology / Q000517:prevention & control; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines
vernacular_title: Primenenie metoda radial'nogo gemoliza dlia opredeleniia antitel k virusam grippa v syvorotkakh liudeĭ.