Therapeutic value of indomethacin in threatened abortion.
One hundred cases of threatened abortion were randomly allocated to four lines of treatment namely, long acting progesterone, antispasmodic, indomethacin and placebo. The lowest success rate was encountered in the indomethacin treated group; symptoms of intolerance were common and three cases out of sixteen turned into missed abortion. Indomethacin does not offer any advantage over other lines of treatment in threatened abortion.
D000077713:17 alpha-Hydroxyprogesterone Caproate; D000030:Abortion, Missed / Q000209:etiology; D000033:Abortion, Threatened / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000627:therapeutic use; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use*; D010276:Parasympatholytics / Q000627:therapeutic use; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second
D006908:Hydroxyprogesterones; D010276:Parasympatholytics; D000077713:17 alpha-Hydroxyprogesterone Caproate; D007213:Indomethacin