Histiocytic lymphoma presenting with extrahepatic biliary obstruction: a report of three cases.
Three patients with histiocytic lymphoma presented with jaundice due to extrahepatic biliary obstruction. Two had widespread disease, but one had a primary lymphoma of the head of the pancreas simulating pancreatic cancer. Biliary bypass surgery was avoided in two patients, both of whom showed resolution of jaundice following treatment with cytotoxic chemotherapeutic drugs.
D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000175:diagnosis*; D001651:Cholestasis, Extrahepatic / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007565:Jaundice / Q000209:etiology* / Q000628:therapy; D008223:Lymphoma / Q000150:complications / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis*