A bactericidal activity of microsomal preparations.
Exposure of suspension of Salmonella typhimurium tester strains TA1535, TA1537 and TA98 to mouse hepatic post-mitochondrial supernatants (S9) resulted in appreciable loss of bacterial viability. This lethal activity was destroyed by heating at 56 degrees C for 30 min. The toxic component of the S9 has not been identified.
D000818:Animals; D000900:Anti-Bacterial Agents; D004353:Drug Evaluation, Preclinical; D005821:Genetic Techniques; D006358:Hot Temperature; D051379:Mice; D008809:Mice, Inbred C3H / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000378:metabolism*
D000900:Anti-Bacterial Agents