Isotope-exchange evidence for allosteric regulation of hexokinase II by glucose 6-phosphate and for an obligatory addition of substrates.
D000494:Allosteric Regulation; D000818:Animals; D002250:Carbon Radioisotopes; D005958:Glucosephosphates / Q000494:pharmacology*; D006593:Hexokinase / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology; D010761:Phosphorus Radioisotopes; D011865:Radioisotope Dilution Technique; D051381:Rats
D002250:Carbon Radioisotopes; D005958:Glucosephosphates; D010761:Phosphorus Radioisotopes; D006593:Hexokinase