[Evaluation of the effect of a high-protein diet in combination with hormone and drug preparations on immunological homeostasis indices in rheumatism patients with a low degree of activity of the disease process].
High protein diet coupled with drugs was used for the treatment of patients with protracted and latent recurrent rheumocarditis. The mean daily doses of the drugs administered were as follows: 2 g of aspirin and 15 mg of prednisolone. With clinical improvement most patients showed a decrease in the amount of blast transformed lymphocytes in stained smears of the cultures of peripheral leukocytes incubated in the presence of cardial antigen, collagen and group C streptococcal nucleoprotein. They also manifested the diminished ability on in vitro sensitized lymphocytes to produce the leukocyte migration inhibition factor.
D000328:Adult; D000917:Antibody Formation / Q000187:drug effects; D001241:Aspirin / Q000627:therapeutic use*; D004044:Dietary Proteins / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007961:Leukocyte Migration-Inhibitory Factors / Q000096:biosynthesis; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use*; D012214:Rheumatic Heart Disease / Q000276:immunology / Q000628:therapy*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D004044:Dietary Proteins; D007961:Leukocyte Migration-Inhibitory Factors; D011239:Prednisolone; D001241:Aspirin
K otsenko vliianiia vysokobelkovoĭ diety v sochetanii s gormonal'no-medikamentoznymi preparatami na nekotorye pokazateli immunologicheskogo gomeostaza u bol'nykh revmatizmom s maloĭ stepen'iu aktivnosti protsessa.