[Amyloid of islets of Langerhans and its relation to diabetes mellitus (author's transl)].
After grading into 4 groups of severity the extent of amyloidosis of the islets of Langerhans was investigated in 60 patients with diabetes and in 60 without. Distinction of 3 stages of diabetes according to clinical parameters showed clear connections between the stage of diabetes and the extent of amyloidosis. Development of amyloid locally may be evidence for progressive B cell insufficiency in diabetes of adults.
D000328:Adult; D000368:Aged; D000682:Amyloid / Q000032:analysis*; D000686:Amyloidosis / Q000150:complications*; D001344:Autopsy; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000473:pathology*; D006801:Humans; D007515:Islets of Langerhans / Q000032:analysis*; D008875:Middle Aged
D000682:Amyloid
Das Amyloid der Langerhansschen Inseln und seine Beziehung zum Diabetes mellitus.