Renin precursor from mouse kidney identified by cell-free translation of messenger RNA.
1. The biosynthetic precursor of renin (preprorenin) from mouse kidney is a single chain polypeptide with a molecular weight of 50 000. 2. This is the same value as previously found for mouse submaxillary gland pre-prorenin. 3. Mouse kidney pre-prorenin (mol. wt. 50 000) is larger than the enzymatically active renin (mol. wt. 40 000).
D000818:Animals; D001345:Autoradiography; D002474:Cell-Free System; D004591:Electrophoresis, Polyacrylamide Gel; D004792:Enzyme Precursors / Q000096:biosynthesis*; D007668:Kidney / Q000378:metabolism*; D051379:Mice; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism*; D012083:Renin / Q000096:biosynthesis*
D004792:Enzyme Precursors; D012333:RNA, Messenger; D012083:Renin