A double-blind comparative trial of dothiepin and imipramine for the treatment of depressive inpatients.
Thirty-six inpatients took part in a double-blind comparative study of dothiepin and imipramine; objective and subjective ratings were completed weekly for a four week period. Dothiepin was as effective as imipramine in its antidepressive effect with less side effects statistically demonstrated.
D000328:Adult; D002986:Clinical Trials as Topic; D003863:Depression / Q000188:drug therapy*; D003988:Dibenzothiepins / Q000627:therapeutic use*; D004308:Dothiepin / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007099:Imipramine / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male
D003988:Dibenzothiepins; D007099:Imipramine; D004308:Dothiepin