title: Cerebrospinal fluid-contacting area in the pineal recess of the vole (Microtus agrestis), guinea pig (Cavia cobaya), and rhesus monkey (Macaca mulatta).
abstract: The ventricular lining in the pineal recess of the vole (Microtus agrestis), guinea pig (Cavia cobaya) and Rhesus monkey (Macaca mulatta) was investigated light and electron microscopically. Deep in the pineal recess of all three species the ependymal lining exhibits interruptions. A varying proportion of pinealocytes penetrates through this ependymal area, so that the surface of the protruding cells is directly exposed to the cerebrospinal fluid (CSF). At their base, these cells are anchored in the hypependymal tissue by means of processes. It is conjectured that these pinealocytes are engaged in secreting pineal substances into the CSF, as various physiological findings appear to indicate.
mesh_terms: D000818:Animals; D003411:Arvicolinae; D001253:Astrocytes / Q000648:ultrastructure; D002555:Cerebrospinal Fluid / Q000502:physiology*; D004805:Ependyma / Q000166:cytology*; D006168:Guinea Pigs; D008253:Macaca mulatta; D008322:Mammals / Q000033:anatomy & histology*; D009940:Organoids / Q000648:ultrastructure; D010870:Pineal Gland / Q000166:cytology*; D013569:Synapses / Q000648:ultrastructure