[Quantitative immunoenzyme method of analyzing embryonal prealbumin (EPA-1) in biological fluids].
A quantitative immunoenzymatic method (ELISA) has been developed for detection of embryonic prealbumin (EPA-1). This method allows EPA-1 to be detected in human serum in an amount of 4 to 100 ng/ml. The high levels of EPA-1 (over 4 ng/ml) were observed in all cases (27 patients) of tumors of connective tissues, in 50 of 51 in brain tumors, in 39 of 341 in gastrointestinal tract tumors, in 4 of 13 in breast tumors, and in 21 of 51 tumors of the respiratory tract. The levels of EPA-1 in donors and pregnant woman sera normally did not exceed 4 ng/ml. However, about 3% of the samples of these sera had the levels of EPA-1 from 4 to 12 ng/ml.
D001859:Bone Neoplasms / Q000097:blood; D001932:Brain Neoplasms / Q000097:blood; D002357:Cartilage Diseases / Q000097:blood; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D009369:Neoplasms / Q000097:blood*; D011228:Prealbumin / Q000032:analysis*; D011247:Pregnancy; D012142:Respiratory Tract Neoplasms / Q000097:blood; D012709:Serum Albumin / Q000032:analysis*; D012983:Soft Tissue Neoplasms / Q000097:blood
D011228:Prealbumin; D012709:Serum Albumin
Kolichestvennyĭ immunofermentnyĭ metod opredeleniia émbrional'nogo preal'bumina (EPA-1) v biologicheskikh zhidkostiakh.