Diagnosis of meconium in amniotic fluids by nuclear magnetic resonance spectroscopy.
Some 40 samples of amniotic fluids were studied by nuclear magnetic resonance (NMR) spectroscopy as the first step in developing techniques for analysis of amniotic fluids in vivo without amniocentesis. It was found possible to distinguish amniotic fluids containing meconium (fetal feces) from all other kinds of amniotic fluids (hydramnios or normal fluids) by proton NMR, but precise chemical or cytological analysis seemed unavailable. Also reported are results of in vitro analysis of amniotic fluids, and of measurements performed in vivo on other biologic fluids to investigate possible in situ detection of pathological amniotic fluids.
D000653:Amniotic Fluid / Q000032:analysis*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D009682:Magnetic Resonance Spectroscopy; D008470:Meconium / Q000032:analysis*; D006831:Polyhydramnios / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis