title: [Osteonecroses in children with chronic renal diseases before and after kidney transplantation (author's transl)].
abstract: From 1969 to 1980 202 children suffering from chronic renal insufficiency underwent treatment in the Children's Hospital of Heidelberg University. In 36 patients kidney transplantation were performed. Two children developed femoral head necroses before transplantation without corticosteroid therapy. Three patients developed femoral head necroses in one or both sides within one to 24 months after kidney transplantation. All children with femoral head necrosis were suffering from congenital renal disease and had a history of severe renal osteodystrophy which was followed by severe coxa vara. Coxa vara and the resulting faulty loading seem to be essential factors for the development of femoral head necrosis in patients with renal insufficiency before and after kidney transplantation.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D005260:Female; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000209:etiology*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000151:congenital; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D011859:Radiography
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Osteonekrosen bei Kindern mit chronischen Nierenerkrankungen vor und nach Nierentransplantation.