[Protective properties of antigenic complexes of Proteus].
To determine the possibility of the specific therapy and prevention of Proteus infection, the protective activity of antigenic complexes extracted from Pr. mirabilis cells by various methods was studied. Immunization of mice with these antigens rendered the animals resistant to challenge with a virulent Proteus strain, and the therapeutic injection of the antigens alleviated the infectious process developing as a result of intradermal infection. The blood sera of the treated rabbits acquired capacity of protecting mice from the Proteus infection.
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001428:Bacterial Vaccines / Q000276:immunology / Q000627:therapeutic use; D007116:Immunization, Passive; D051379:Mice; D011512:Proteus Infections / Q000517:prevention & control* / Q000628:therapy; D011513:Proteus mirabilis / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D014611:Vaccination
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines
Protektivnye svoĭstva antigennykh kompleksov proteia.