[Delay of early rejection of intrasplenic pancreatic allotransplants by fractional splenic irradiation in dogs (author's transl)].
The influence of local irradiation of the spleen and immunosuppressive drugs (cyclophosphamide and azathioprine) on the rejection of intrasplenic pancreatic allotransplants was studied. Fractional splenic irradiation (once 4000-5000 rad before, twice 500-1000 rad after transplantation) prolonged transplant function from 4,1 to 6,5 days, in combination with immunosuppressive therapy to 8,5 days.
D000818:Animals; D004285:Dogs; D006084:Graft Rejection / Q000528:radiation effects*; D016035:Pancreas Transplantation; D013154:Spleen / Q000528:radiation effects* / Q000601:surgery; D014184:Transplantation, Homologous
Verzögerung der Frühabstossung von intralienalen Pankreas-Allotransplantaten durch fraktionierte Milzbestrahlung beim Hund.