Cause and course of acute myocardial infarction.
A complete discussion of factors involved in causing acute myocardial infarcts is contained in ths review, and a detailed discussion of various complications of acute myocardial infarction is also provided. Interventions that are capable of reducing infarct size in animal models with experimentally produced acute myocardial infarcts are discussed, and factors that might alter infarct size in patients are reviewed. Prognostic factors that allow one to identify high risk patients with acute myocardial infarction following their hospital admission and in the follow-up period after hospital discharge are identified. The need to develop more accurate measurements of the extent of myocardial infarction and myocardial ischemia, and to develop additional prognostic markers that allow one to separate patients most at risk for sudden death and new myocardial infarction from those with ongoing chronic ischemic heart disease and those without additional complications from their ischemic heart disease is also emphasized in this review.
D000208:Acute Disease; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001161:Arteriosclerosis / Q000150:complications; D002784:Cholesterol / Q000378:metabolism; D003327:Coronary Disease / Q000150:complications; D006327:Heart Block / Q000209:etiology; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000209:etiology* / Q000628:therapy; D011379:Prognosis; D012306:Risk
D002784:Cholesterol