[Use of the edema test of the extremities in white mice for studying purulent Proteus infection].
The injection of non-enterotoxigenic Proteus strains into the paw pad of white mice caused paw edema, its intensity being proportional to the dose used for the test. The exudate consisted of granulocytes. Immunization with isolated Proteus antigens prevented the development of edema. This test is recommended as a model of local purulent infection. The optimal methods for the statistical analysis of the results thus obtained is proposed.
D000818:Animals; D000942:Antigens, Bacterial / Q000008:administration & dosage; D004195:Disease Models, Animal; D004306:Dose-Response Relationship, Immunologic; D004487:Edema / Q000276:immunology / Q000382:microbiology*; D005534:Foot Diseases / Q000276:immunology / Q000382:microbiology*; D051379:Mice; D011512:Proteus Infections / Q000276:immunology / Q000382:microbiology*; D011513:Proteus mirabilis / Q000276:immunology
D000942:Antigens, Bacterial
Primenenie testa oteka konechnosteĭ belykh mysheĭ dlia izucheniia proteĭnoĭ gnoerodnoĭ infektsii.