title: Influence of spasmolytic treatment and amniotomy on delivery times: a factorial clinical trial.
abstract: In a double-blind factorial clinical trial in 300 patients (150 primiparae and 150 multiparae), the effects of amniotomy, rociverine, and butylscopolamine bromide administration on the course of labor were investigated. Rociverine significantly reduced the dilatation time and had no effect on the delivery time. Butylscopolamine bromide had no appreciable effect on the dilatation and expulsion times. Amniotomy resulted in a lengthening of the dilatation time and no significant change in the expulsion time.
mesh_terms: D000650:Amnion / Q000601:surgery*; D001643:Bridged Bicyclo Compounds / Q000627:therapeutic use; D002086:Butylscopolammonium Bromide / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003509:Cyclohexanecarboxylic Acids; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007743:Labor, Obstetric / Q000187:drug effects; D010276:Parasympatholytics / Q000627:therapeutic use*; D011247:Pregnancy; D013997:Time Factors
chemical_list: D001643:Bridged Bicyclo Compounds; D003509:Cyclohexanecarboxylic Acids; D010276:Parasympatholytics; D002086:Butylscopolammonium Bromide; C021082:rociverine