[Neonatal meningitis (personal contribution)].
The authors, after a review of the literature about etiology, pathogenesis, epidemiology, pathological anatomy and clinic of newborn meningitis, report a personal experience of 15 cases. The more frequent etiological agents were Gram-positive bacteria (60%) and in particular Listeria monocytogenes type 4 and Streptococcus agalactiae. Gram-negative bacteria were isolated in 40% of cases and E. coli presented the highest ratio. All patients were treated with ampicillin-CAF association intravenous for the first 3-5 days and then i.m. or oral. The survival ratio was 77% in case of Gram-positive meningitis and 83% in case of Gram-negative meningitis. Sequeles were observed only among patients with Gram-negative meningitis; it's important to remark that in these cases the etiological agent was CAF-resistant.
D002701:Chloramphenicol / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008581:Meningitis / Q000150:complications / Q000188:drug therapy / Q000209:etiology*
D002701:Chloramphenicol
Meningite neonatale (contributo personale).