[In vitro study of the interaction of rubeola virus with the peritoneal macrophages of unimmunized and immunized rats].
In vitro peritoneal macrophage cultures of rats with no immunization against rubella virus and inoculated with these viral agents are prone to permit its intracellular proliferation and suffer a cytopathogenic effect and lysis. Peritoneal macrophages of immune rats do not permit intracellular proliferation and prevent harmful viral action. In the in vivo studies, peritoneal macrophages of non-immune rats eventually show a resistance to rubella virus during the infection. Our results suggest that macrophages require the co-operation of other elements involved in the living animal immunity in order to show resistance to rubella virus.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002455:Cell Division; D003588:Cytopathogenic Effect, Viral; D007114:Immunization; D008264:Macrophages / Q000166:cytology / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D051381:Rats; D014779:Virus Replication
Estudio in vitro de la interacción del virus de la rubéola con los macrófagos peritoneales de ratas no inmunizadas e inmunizadas.