Extractive alkylation of prostaglandins.
The simultaneous extraction and esterification of prostaglandins in aqueous solution is described. High yield of esters can be achieved in a one minute reaction time. The specificity of the alkylation can be controlled by the counterion. Thus, a long chain carboxylic acid can be selectively extracted and derivatized in the presence of PGF2 alpha.
D015121:6-Ketoprostaglandin F1 alpha; D000478:Alkylation; D004537:Eicosanoic Acids; D011464:Epoprostenol; D004951:Esterification; D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D013929:Thromboxane B2
D004537:Eicosanoic Acids; D011453:Prostaglandins; D011458:Prostaglandins E; D011460:Prostaglandins F; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D011464:Epoprostenol