A possible mechanism for "tachyphylaxis' to prazosin in heart failure.
D000804:Angiotensin II / Q000097:blood; D006331:Heart Diseases / Q000188:drug therapy; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D011224:Prazosin / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D011799:Quinazolines / Q000009:adverse effects*; D012083:Renin / Q000097:blood; D013610:Tachycardia / Q000139:chemically induced*
D011799:Quinazolines; D000804:Angiotensin II; D012083:Renin; D011224:Prazosin