[Certain features of the immune response in the presence of a tumor process].
Animal experiments have shown that in the presence of tumor growth immunological stimuli can produce shifts in some reactivity characteristics of the affected organism, which are the reverse of the shifts occurring in a healthy organism under similar conditions. This is attributed to the fact that the immunological stimulus used in these experiments (complete Freund adjuvant) was excessively strong for the affected organism, thus causing the suppression of certain components of reactivity instead of their stimulation. This mechanism is supposed to induce the suppression of the ptocesses lying at the basis of enhanced tumor growth; nevertheless, this suppression is not considered to have a significant positive effect.
D000818:Animals; D001169:Arthritis, Experimental / Q000150:complications; D003165:Complement System Proteins / Q000032:analysis; D005620:Freund's Adjuvant; D006462:Hemolytic Plaque Technique; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D008221:Lymphoid Tissue / Q000276:immunology; D008748:Methylcholanthrene; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000150:complications / Q000276:immunology* / Q000382:microbiology; D051381:Rats; D012867:Skin / Q000382:microbiology
D008748:Methylcholanthrene; D003165:Complement System Proteins; D005620:Freund's Adjuvant
Nekotorye osobennosti immunologicheskogo otveta pri opukholevom protsesse.