title: Conversion of reactions to leprolin and lepromin in patients with lepromatous leprosy by the transfer factor.
abstract: Conversion of leprolin and early lepromin reactions was achieved by two injections of transfer factor made of lymphocytes from lepromin-positive tuberculoid leprosy patients. However, the late reaction to lepromin remained unchanged. The importance of the degree of sensitivity of the cell donor was demonstrated, and a booster dose was also found to be useful. The feasibility of using transfer factor in treatment of lepromatous leprosy is briefly discussed.
mesh_terms: D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007916:Lepromin / Q000276:immunology*; D007918:Leprosy / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009166:Mycobacterium leprae / Q000276:immunology*; D014165:Transfer Factor / Q000276:immunology*; D014373:Tuberculin / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D014165:Transfer Factor; D014373:Tuberculin; D007916:Lepromin