title: [Use of the dynamics of central moments of statistical distributions to analyze muscle fiber differentiation].
abstract: The aim of the work is to demonstrate how it is possible to get informations of differentiation in muscle fibres by means of evaluating the dynamics of statistical distribution moments. Combinations of various directions of time changes of the standard deviations, asymmetry and excess give the possibility to construct tables in order to get immediate informations on changes occurring in different parts of the distribution (and, hence, on the course of the muscle fibres development) during the whole time of observation (age dynamics of NAD-H-D activity in fibres of musculus serratus ventralis in Wistar rats is studied as an example). Analysing dynamics, as well as real distribution features of the muscle fibres, we got doubtful on the presence of muscle fibre types that could be considered as independent (though possibly as over-lapping) populations. Various differentiation rates of the muscle fibres with different optic density do not mean development of a certain population, but rather reflect an increasing process of development of a part of a single muscle fibres complex, where separate members have various properties and in the course of development they smoothly change them in such a way that uninterruption and continuation of possible intermediate conditions is kept along the whole variational curve. This method could be applied to analyse any other objects after any quantitative sign.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006651:Histocytochemistry; D006652:Histological Techniques; D009132:Muscles / Q000166:cytology* / Q000201:enzymology; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D051381:Rats; D013223:Statistics as Topic / Q000379:methods*
chemical_list: D009247:NADH, NADPH Oxidoreductases
vernacular_title: Ispol'zovanie dinamiki tsentral'nykh momentov statisticheskikh raspredeleniĭ dlia analiza differentsiatsii myshechnykh volokon.