title: Historical notes on breast cancer, with emphasis on the Netherlands. I. Pathological and therapeutic concepts in the seventeenth century.
abstract: The history of carcinoma was for many centuries mainly the history of breast cancer. Only when in the second half of the 19th century anaesthesia and antisepsis had enabled surgery to treat certain internal carcinomas as well, interest in malignancies other than those of the breast sprang into being.
mesh_terms: D001943:Breast Neoplasms / Q000266:history* / Q000601:surgery; D005260:Female; D049670:History, 17th Century; D006801:Humans; D008408:Mastectomy / Q000266:history* / Q000295:instrumentation; D009426:Netherlands; D013525:Surgical Instruments / Q000266:history