The prophylactic use of metronidazole in caesarean section.
A double-blind study of 73 patients was undertaken to evaluate the prophylactic effect of short-term metronidazole in caesarean section. Metronidazole, 500 mg, given intravenously prior to making the incision, followed by 2 g, rectally, on completion of surgery failed to reduce the incidence of infection post-operatively. There was no reduction in the number of patients requiring antibiotics or in the quantity of post-operative pyrexia, as assessed by the fever index. The incidence of post-operative pyrexia was not affected by the duration of ruptured membranes or the use of a fetal scalp electrode.
D001424:Bacterial Infections / Q000517:prevention & control*; D002585:Cesarean Section; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D011247:Pregnancy; D011292:Premedication
D008795:Metronidazole