Cadaveric kidneys for transplantation. A paradox of shortage in the face of plenty.
The number of cadaveric kidneys currently available for transplantation is insufficient; therefore, the Center for Disease Control (CDC) undertook a collaborative pilot project to increase the number of cadaveric kidneys available for transplantation. In phase one, a retrospective review of medical records of in-hospital deaths was done to determine the potential number of cadaveric kidney donors and to define the characteristics of potential donors. The medical records of 10,420 (43.1%) of the 24,164 patients who died in 67 acute-care hospitals in Georgia, Kansas, and Missouri were retrieved. In addition to determining suitability for donorship, criteria were developed to reflect the broadest range of criteria in use. By center-specific criteria there were 1.7 potential donors/100 in-hospital deaths, which could make available 109 kidneys/million population. By broad intercenter criteria there were 3.5 potential donors/100 in-hospital deaths, which could provide 232 kidneys/million population. During 1975, by center-specific criteria, kidneys from 19.3% of the suitable potential donors were retrieved. The small number of transplantable cadaveric kidneys retrieved was not attributable to lack of suitable organs but rather the failure to identify suitable donors, obtain consent, and retrieve the kidneys.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002102:Cadaver; D002648:Child; D002675:Child, Preschool; D006259:Craniocerebral Trauma / Q000401:mortality; D005260:Female; D006470:Hemorrhage / Q000401:mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016030:Kidney Transplantation; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009423:Nervous System Neoplasms / Q000401:mortality; D014019:Tissue Donors; D014652:Vascular Diseases / Q000401:mortality