title: Diagnostic potentialities of enzyme-linked immunosorbent assay in tuberculosis using purified tuberculin antigen.
abstract: Delayed hypersensitivity tests with tuberculin or purified tuberculin (PPD) have been used for detection of tuberculous infection. The present paper describes an enzyme-linked immunosorbent assay (ELISA) for detection of PPD-antibodies in tuberculosis patients. The ELISA test was positive in nearly 80% of cases having bacteriological evidence of tuberculosis. The test could also detect PPD-antibodies in 66% of the cases not showing bacteriological evidence of tuberculosis. The potentiality of the test in the immunodiagnosis of tuberculosis is discussed.
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007124:Immunoenzyme Techniques; D014373:Tuberculin / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis*
chemical_list: D000942:Antigens, Bacterial; D014373:Tuberculin