Immunoreactive glucagon and insulin C-peptide in man after resection of the pancreas and total pancreatectomy.
Pancreatic-type glucagon (PTG) has been found in the plasma of totally pancreatectomized human beings. Arginine infusion, however, caused no increase in PTG. Pancreas-resected patients had a normal response of PTG to arginine and a subnormal increase in C peptide. Gut glucagon-like immunoreactants (gut GLI) were increased in resected patients and further increased in totally pancreatectomized patients. Gut GLI showed no change during arginine stimulation.
D000328:Adult; D000368:Aged; D001120:Arginine; D002096:C-Peptide / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D005934:Glucagon / Q000097:blood*; D004763:Glucagon-Like Peptides / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000502:physiology*; D010180:Pancreatectomy; D010195:Pancreatitis / Q000601:surgery; D010455:Peptides / Q000097:blood*; D011863:Radioimmunoassay
D002096:C-Peptide; D007328:Insulin; D010455:Peptides; D004763:Glucagon-Like Peptides; D005934:Glucagon; D001120:Arginine