title: [Study of induction of mitochondrial mutations in Saccharomyces cerevisiae yeasts following exposure to ethyl alcohol].
abstract: The kinetics of the killing and petite-inducing effects of ethanol has been studied at 6-30% concentrations. The results obtained indicate that the ploidy of cells or holding them under no-growth conditions do not influence on their survival. Ethanol increased the number of respiration-deficient cells from spontaneous level (0.46%) up to nearly half of all survivors at 24% and 30% ethanol concentrations. The genetic analysis has shown the mitochondrial nature of induced respiration deficiency.
mesh_terms: D004272:DNA, Mitochondrial / Q000235:genetics*; D000431:Ethanol / Q000494:pharmacology*; D008928:Mitochondria / Q000378:metabolism; D009153:Mutagens; D010101:Oxygen Consumption; D011003:Ploidies; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism
chemical_list: D004272:DNA, Mitochondrial; D009153:Mutagens; D000431:Ethanol
vernacular_title: Izuchenie induktsii mitokhondrial 'nykh mutatsiĭ u drozhzheĭ Saccharomyces cerevisiae pri deĭstvii étilovogo spirta.