title: The nature of negative cooperativity in alkaline phosphatase. Kinetic patterns contrary to the flip-flop model.
mesh_terms: D000249:Adenosine Monophosphate; D000469:Alkaline Phosphatase / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology; D007700:Kinetics; D008433:Mathematics; D010761:Phosphorus Radioisotopes; D011865:Radioisotope Dilution Technique
chemical_list: D010761:Phosphorus Radioisotopes; D000249:Adenosine Monophosphate; D000469:Alkaline Phosphatase