Bone marrow transplantation in a child with acute lymphoblastic leukaemia.
A caucasian female infant with acute lymphoblastic leukaemia in second remission received a bone marrow transplantation. Engraftment was confirmed at 14 days following infusion of bone marrow from a sex-matched, ABO and HLA compatible sibling. 171 days posttransplantation the patient is clinically well and in haematological remission. A mild transient skin rash and hepatocellular disturbance, the only manifestations of graft versus host disease, responded successfully to high dose prednisone.
D016026:Bone Marrow Transplantation; D002675:Child, Preschool; D005260:Female; D006087:Graft vs Host Reaction / Q000187:drug effects; D006801:Humans; D007945:Leukemia, Lymphoid / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D014184:Transplantation, Homologous
D011241:Prednisone