title: Biotransformation of the pesticide sodium arsenate.
abstract: Biotransformation is an important parameter in assessing the environmental impact and fate of pesticides since metabolites produced may be either more or less toxic than the parent compound. Sodium arsenate (+5 inorganic), the wood preservative and insecticide, may be converted to both inorganic (+3) and organic compounds (-3) by microorganisms in soil, sediment and water bodies. Biotransformation of sodium arsenate was studied in pure cultures of 5 bacterial species using a mineral salt and limited carbon source medium. Arsenate concentrations were 10 microgram/ml and 100 microgram/ml of arsenic respectively. The rate of biodegradation of the parent compound was described by a first order composite exponential equation of the form Ct = C1e-k1t+C2e-k2t. Rates of production of metabolites (arsenite, monomethylarsine, dimethylarsine and trimethylarsine) were described by a first order exponential equation of the form Ct = Co (1-e-kt).
mesh_terms: D001149:Arsenates / Q000378:metabolism*; D001151:Arsenic / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001711:Biotransformation; D003352:Corynebacterium / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000378:metabolism; D005417:Flavobacterium / Q000378:metabolism; D006207:Half-Life; D007700:Kinetics; D011511:Proteus / Q000378:metabolism; D011549:Pseudomonas / Q000378:metabolism; D013045:Species Specificity
chemical_list: D001149:Arsenates; C009277:sodium arsenate; D001151:Arsenic