Meiosis in Sxr male mice: II. Further absence of cytological evidence for a Y-autosome rearrangement in sex-reversed (Sxr) mice.
If the sex-reversal factor (Sxr) in mice is represented by a segment of the Y chromosome translocated on to an autosome, this segment might be expected to show some evidence of attempted pairing with the normal Y chromosome at the first meiotic division. Our failure to find such evidence in a light microscope study of the silver-stained pachytene spermatocytes from Sxr/4, XY males further supports existing cytological information that the factor is more likely to be represented by an autosomal dominant gene mutation.
D000818:Animals; D002875:Chromosomes / Q000648:ultrastructure*; D003584:Cytological Techniques; D012734:Disorders of Sex Development / Q000235:genetics*; D005260:Female; D008297:Male; D008540:Meiosis; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics; D012730:Sex Chromosomes / Q000648:ultrastructure*; D012834:Silver; D014178:Translocation, Genetic; D014998:Y Chromosome / Q000648:ultrastructure*
D012834:Silver