Neonatal jaundice: the surgical viewpoint.
There is good evidence that neonatal hepatitis, biliary hypoplasia, biliary atresia and choledochal cyst are different stages of one disease process for which the term infantile obstructive cholangiopathy has been suggested. Thanks to the work of Kasai and the operation of hepatic portoenterostomy the surgical outlook has greatly improved, although in North America it still leaves much to be desired. One cannot procrastinate too long in the hope that the patient's condition will improve spontaneously, because the surgical results are much better when the operation is performed before the patient is 10 weeks old. This article outlines the steps that should be followed in investigating neonatal jaundice, the nonsurgical measures that can be taken in an attempt to reverse or alleviate the underlying condition, and the specific role of the pediatric surgeon in the management of choledochal cyst and biliary atresia.
D001652:Bile Ducts / Q000002:abnormalities* / Q000601:surgery; D002780:Cholestasis, Intrahepatic / Q000150:complications / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D007583:Jejunum / Q000601:surgery; D008111:Liver Function Tests; D016031:Liver Transplantation; D011379:Prognosis; D014184:Transplantation, Homologous