Biochemical evidence for an interaction of ethanol and stress: preliminary studies.
Studies were carried out to examine the interaction of stress and ethanol. Ethanol (0.5 g/kg)-treated, stressed (electric foot shocks) rats exhibited less marked elevations in plasma levels of nonesterified fatty acids and of corticosterone compared to saline-treated stressed subjects. Stress alone markedly elevated these two parameters in plasma. Ethanol treatment alone also resulted in small elevations in both parameters. Results provide support for a significant interaction of ethanol and stress, and might provide some basis for the purported stress-relieving effect of low doses of ethanol.
D000818:Animals; D003345:Corticosterone / Q000097:blood; D004597:Electroshock; D000431:Ethanol / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D008297:Male; D051381:Rats; D013312:Stress, Physiological / Q000503:physiopathology*
D005230:Fatty Acids, Nonesterified; D000431:Ethanol; D003345:Corticosterone