[Mechanism of the stimulating effect of furosemide, ethacrynic acid and novurit on renin secretion by the kidneys].
It was shown in chronic experiments on dogs that denervation of the kidneys does not eliminate the stimulant action of furosemid, etacrinic acid and novurit. Stoppage of the urine flow in dogs with a denervated single kidney did not lead to a complete removal of the stimulant effect of the diuretics on renin secretion.
D000479:Alkylmercury Compounds / Q000494:pharmacology*; D000818:Animals; D003714:Denervation; D004231:Diuresis / Q000187:drug effects; D004285:Dogs; D004338:Drug Combinations / Q000494:pharmacology; D004976:Ethacrynic Acid / Q000494:pharmacology*; D005260:Female; D005665:Furosemide / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects* / Q000294:innervation / Q000378:metabolism; D008297:Male; D009941:Organomercury Compounds / Q000494:pharmacology*; D012083:Renin / Q000097:blood / Q000378:metabolism*; D013268:Stimulation, Chemical; D013806:Theophylline / Q000494:pharmacology*
D000479:Alkylmercury Compounds; D004338:Drug Combinations; D009941:Organomercury Compounds; C021054:mercurophylline; D005665:Furosemide; D013806:Theophylline; D012083:Renin; D004976:Ethacrynic Acid
Mekhanizm stimuliruiushchego vliianiia furosemida, étakrinovoĭ kosloty i novurita na sekretsiiu renina pochkami.