Allergic perennial and non-allergic, vasomotor rhinitis treated with budesonide nasal spray.
A recently synthetized, highly active, non-halogenated steroid, budesonide, in the form of a nasal spray was tested on 21 patients with an allergy demonstrated by means of cutaneous or RAST tests and 15 patients without allergy; these patients were further divided into two groups, 22 with nasal eosinophillia and 14 patients without. There was a significant effect on both patients with vasomotor as well as allergic rhinitis, and in patients with nasal eosinophilia, while this was not the case in the group without eosinophilia. Nasal eosinophilia must be considered an inexpensive and important diagnositic tool for the clarification of perennial rhinitis.
D000293:Adolescent; D000328:Adult; D019819:Budesonide; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004802:Eosinophilia / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011282:Pregnenediones / Q000627:therapeutic use*; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000097:blood / Q000188:drug therapy*; D012223:Rhinitis, Vasomotor / Q000097:blood / Q000188:drug therapy*
D011282:Pregnenediones; D019819:Budesonide