title: An investigation into some of the factors concerned in the surgical removal of the impacted lower wisdom tooth, including a double blind trial of chymoral.
abstract: During the surgical extraction of 102 impacted lower wisdom teeth the following factors were studied: the amount of trauma applied during tooth removal; the duration of the operation; post-operative swelling; post-operative trismus; sex differences; the relationship between swelling and trismus; the pattern of development and subsidence of swelling and trismus. This study was combined with a clinical 'double-blind' trial of the drug Chymoral.
mesh_terms: D002918:Chymotrypsin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003748:Dental Equipment; D004311:Double-Blind Method; D004338:Drug Combinations / Q000627:therapeutic use; D004487:Edema / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008963:Molar / Q000601:surgery*; D010497:Pericoronitis / Q000209:etiology; D010780:Photogrammetry / Q000295:instrumentation; D011183:Postoperative Complications / Q000188:drug therapy; D014081:Tooth Extraction / Q000379:methods*; D014095:Tooth, Impacted / Q000601:surgery*; D014313:Trismus / Q000209:etiology; D014357:Trypsin / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; C007059:chymotrypsin, trypsin drug combination; D002918:Chymotrypsin; D014357:Trypsin