A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury.
A double-blind, non-crossover, randomized trial was carried out in 50 patients suffering from pain following trauma to compare the therapeutic effectiveness and tolerance of 200 mg tiaprofenic acid and 600 mg aspirin given 3-times daily for 7 days. Both drugs were found to be equally effective in relieving pain but side-effects were significantly fewer in the tiaprofenic acid-treated group.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D011422:Propionates / Q000627:therapeutic use*; D013876:Thiophenes / Q000627:therapeutic use*; D014947:Wounds and Injuries / Q000150:complications
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011422:Propionates; D013876:Thiophenes; C021270:tiaprofenic acid; D001241:Aspirin