[Pain reduction in peripheral arteriographies of the upper and lower extremities in a double blind test. Lidocain/ioglicinate versus metrizamide (author's transl)].
36 aortofemoral and 18 brachial angiographies effected under standardized conditions in a double blind test in approximately two equal parts with Lidocain/Ioglicinate and Metrizamide, respectively, were evaluated with regard to vascular pain and sensation of heat during the examination. With the femoralis angiograms reduction of vascular pain was on the average somewhat greater, although this could not be established statistically when using Metrizamide. In the case of the angiogram of the arm, pain was on the average equally low in both cases. Of the 14 patients who had received injections of both contrast media in varying succession at intervals of 20 minutes, 6 patients considered the Metrizamide injection to be more agreeable, whereas 2 preferred the Lidocain/Ioglicinate injection and 6 patients did not notice any significant difference. The average sensation of heat during contrast medium visualisation of the legs and arms was equal with both substances. Lidocain/Ioglicinate and Metrizamide are approximately equally well suited for peripheral angiography of arms and legs, rendering narcosis and strapping down of the extremities unneccessary in normal cases.
D000772:Anesthesia, Local / Q000592:standards; D000792:Angiography; D001132:Arm / Q000098:blood supply* / Q000000981:diagnostic imaging; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000592:standards; D004311:Double-Blind Method; D006801:Humans; D007463:Iodobenzoates / Q000008:administration & dosage*; D007471:Ioglycamic Acid / Q000008:administration & dosage*; D007866:Leg / Q000098:blood supply* / Q000000981:diagnostic imaging; D008012:Lidocaine / Q000008:administration & dosage*; D008793:Metrizamide / Q000008:administration & dosage*
D003287:Contrast Media; D007463:Iodobenzoates; D008012:Lidocaine; D007471:Ioglycamic Acid; D008793:Metrizamide
Schmerzreduktion bei peripheren Arteriographien der oberen und unteren Extremität im Doppelblindversuch. Lidocain/loglicinat gegen Metrizamid.