Studies on the K antibody response in rabbits immunized with a pool of five different K antigen-containing Escherichia coli.
The Escherichia coli K antibody response in rabbits which were immunized with a mixture of E. coli O1K1H7, O6K2a2cH1, O4K12, O6K13H1 and O6K53, or with only one of these strains, was analyzed using indirect hemagglutination. Some K antigens gave generally high antibody response, while others did not. There were not statistically significant difference concerning K antibody response for each of the K antigens when the rabbits were immunized with one strain or a mixture of strains. The information is important for the composition of a future E. coli vaccine containing several K antigens.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000942:Antigens, Bacterial; D004926:Escherichia coli / Q000276:immunology*; D007114:Immunization; D011817:Rabbits; D014552:Urinary Tract Infections / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial