[Primary postural hypotension. Physiopathological study of 8 cases (author's transl)].
Physiological tests showed that both branches of the baroreflex arc-vagal cardiomoderator and, predominantly, sympathetic vasoconstrictor--were affected. There was no rise in serum and urinary noradrenaline levels in standing position, and adrenaline concentrations were rarely increased under induced hypoglycaemia. Dopamine beta-hydroxylase activity and reactivity of the renin-angiotensin-aldosterone system remained normal in most cases. Physiopathologically, the two clinical forms described (i.e. with and without central nervous symptoms) cannot be differentiated.
D000368:Aged; D000450:Aldosterone / Q000097:blood; D002395:Catecholamines / Q000652:urine; D004299:Dopamine beta-Hydroxylase / Q000097:blood; D005260:Female; D006339:Heart Rate; D006801:Humans; D007024:Hypotension, Orthostatic / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012018:Reflex / Q000502:physiology; D012083:Renin / Q000097:blood; D013564:Sympathetic Nervous System / Q000503:physiopathology; D014630:Vagus Nerve / Q000503:physiopathology
D002395:Catecholamines; D000450:Aldosterone; D004299:Dopamine beta-Hydroxylase; D012083:Renin
Hypotension orthostatique primitive. Etude physiopathologique de 8 observatins.