[Obesity and the nociceptive reflex (author's transl)].
Using electrophysiological methods for studying pain in human, the authors have studied comparatively the sensation of pain and the threshold of a nociceptive flexion reflex of the lower limb, both elicited by electrical stimulation of sural nerve in 20 obese women (weight greater than or equal to 30 p. 100 of ideal weight) and 14 normal weighing women as controls. In obeses, the threshold of the nociceptive flexion reflex is very significantly lower (5,4 +/- 2 mA in obesity, 9,7 +/- 1,6 mA in controls p < 0,0001). The authors suggests an hypothesis of insufficiency of endogenous opiate releasing in human obesity.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004594:Electrophysiology; D004723:Endorphins / Q000502:physiology; D004745:Enkephalins / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology*; D010146:Pain / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology
D004723:Endorphins; D004745:Enkephalins
Obésité et baisse du seuil nociceptif.