title: Low dose subcutaneous heparin and wound hematoma formation in inguinal hernia operations--a double-blind randomized clinical trial.
abstract: Postoperative wound bleeding and wound hematoma formation were studied in a prospective double-blind randomized clinical trial in selected patients undergoing surgery for inguinal hernia. With careful surgical technique, prophylactic administration of low dose subcutaneous heparin did not result in a significant increase in wound hematoma formation or wound bleeding. The postoperative decrease in the hemoglobin concentration, resulting from operative and postoperative blood loss, was -0.59 mmol/l, +/- 0.54 SD, in the control group and -0.60 mmol/l, +/- 0.57 SD, in the heparin group.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006406:Hematoma / Q000139:chemically induced*; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D011897:Random Allocation
chemical_list: D006493:Heparin