Individual differences in blood and breath acetaldehyde levels and urinary excretion of catecholamines after alcohol intake.
Sixty three male Japanese, aged 20-40 yr were evaluated as to the degree of facial flushing following a controlled dose of ethanol either as Japanese rice wine or ethanol 0.4 g kg body weight. Thirty four subjects responded with overt facial flushing. The acetaldehyde levels in blood and expired air were significantly higher in the flushing group without a change in ethanol elimination rate. Urinary excretion of Vanilmandelic acid (VMA) and 3 methyoxy-4-Hydroxyphenylglycol (MHPG) are reported.
D000079:Acetaldehyde / Q000097:blood / Q000378:metabolism*; D000328:Adult; D001944:Breath Tests; D002395:Catecholamines / Q000652:urine*; D004298:Dopamine / Q000652:urine; D004837:Epinephrine / Q000652:urine; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000652:urine; D009638:Norepinephrine / Q000652:urine; D014642:Vanilmandelic Acid / Q000652:urine
D002395:Catecholamines; D000431:Ethanol; D008734:Methoxyhydroxyphenylglycol; D014642:Vanilmandelic Acid; D000079:Acetaldehyde; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine