Results of kidney transplantation in relation to HLA-A, B, DR matching and quality of donor organ.
The influence of HLA compatibility as well as immediate postoperative function on survival rates was investigated in 203 cadaver kidney transplants. HLA compatibility, especially DR compatibility, improved transplant survival significantly. A direct correlation was found between primary transplant function and long-term results. HLA compatibility and quality of the donor organ had a cumulative effect on kidney transplant survival. Our results are a further indication that besides HLA compatibility, optimal quality of donor organs has crucial significance for the results of transplantation.
D005500:Follow-Up Studies; D006085:Graft Survival; D006680:HLA Antigens / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D007511:Ischemia / Q000175:diagnosis; D007668:Kidney / Q000098:blood supply / Q000276:immunology; D016030:Kidney Transplantation; D011183:Postoperative Complications; D014184:Transplantation, Homologous
D006680:HLA Antigens; D000949:Histocompatibility Antigens Class II