Study of the efficacy of compound Go.9333 (Ciba-Geigy) in hookworm infestation.
50 cases with hookworm infestation were studied to find out the species of the parasite, 25 of them were included for a double-blind trial of compound Go.9333 (Ciba-Geigy)/placebo. Results of the study revealed predominance of Necator americanus (96%) in and around Pondicherry, South India. Compound Go.9333 was found to very effective in the treatment of hookworm infestation. Side effects were minor and were not of much significance. The drug was well accepted and tolerated by most of the cases. On the basis of the present study, compound Go.9333 can be recommended for the treatment of hookworm infestation.
D000814:Aniline Compounds / Q000627:therapeutic use*; D000969:Antinematodal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004159:Diphenylamine / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use*; D004311:Double-Blind Method; D006725:Hookworm Infections / Q000188:drug therapy* / Q000469:parasitology / Q000503:physiopathology; D006801:Humans; D017879:Isothiocyanates; D013861:Thiocyanates / Q000009:adverse effects / Q000627:therapeutic use*
D000814:Aniline Compounds; D000969:Antinematodal Agents; D017879:Isothiocyanates; D013861:Thiocyanates; D004159:Diphenylamine; C012391:amoscanate