[Testicular atrophy and gonadotropin activity in rats with portacaval anastomosis].
Rats subjected to porto-caval shunt present, even after a rather long period since the operation (5 months), a moderate atrophy of the testicles. This phenomenon occurs because of a reduced gonadotropic activity of the pituitary gland, consequent upon a more or less increased inhibition of the hypothalamic GTH-RF production. The abnormal depression of the hypothalamic activity is due to a scarce metabolism of the sexual hormones following the operation.
D000818:Animals; D001284:Atrophy; D006065:Gonadotropins, Pituitary / Q000096:biosynthesis*; D008297:Male; D010906:Pituitary Hormone-Releasing Hormones / Q000378:metabolism; D011167:Portacaval Shunt, Surgical / Q000009:adverse effects*; D011183:Postoperative Complications; D051381:Rats; D013737:Testis / Q000473:pathology*
D006065:Gonadotropins, Pituitary; D010906:Pituitary Hormone-Releasing Hormones
Atrofia testicolare e attività gonadotropa in ratti con anastomosi porto-cava.