title: Investigations into the in vitro and in vivo immunosuppressant activity of N-acetyl-3-sulphonamoyl-L-alanine methyl ester, a potential L-asparagine antimetabolite.
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000963:Antimetabolites / Q000494:pharmacology*; D001215:Asparaginase / Q000494:pharmacology; D001216:Asparagine / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects; D004926:Escherichia coli / Q000201:enzymology; D007166:Immunosuppressive Agents; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D051379:Mice; D013449:Sulfonamides / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism
chemical_list: D000963:Antimetabolites; D007166:Immunosuppressive Agents; D013449:Sulfonamides; C025973:N-acetyl-3-sulfonamoyl-L-alanine methyl ester; D001216:Asparagine; D001215:Asparaginase; D000409:Alanine; D013936:Thymidine