48-hour cephradine and post-prostatectomy bacteriuria.
In a randomised, controlled trial of intramuscular cephradine given in a dose of 1 g 6-hourly for 48 h, there was a significant reduction in the incidence of significant bacteriuria after transurethral resection. In contrast, the incidence of significant bacteriuria after open prostatectomy was unchanged. Post-operative complications were reduced in patients who received cephradine. The use of short-term cephradine would appear to be justified.
D000368:Aged; D001437:Bacteriuria / Q000209:etiology / Q000517:prevention & control*; D002511:Cephalosporins / Q000627:therapeutic use*; D002515:Cephradine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011468:Prostatectomy / Q000379:methods*; D011469:Prostatic Diseases / Q000150:complications; D014546:Urinary Catheterization
D002511:Cephalosporins; D002515:Cephradine