[A double blind trial : oxprenolol/diazepam (author's transl)].
This double blind trial oxprenolol/diazepam has been realised after open comparative trials performed with three other drugs and involving about one hundred ambulatory patients. Anxiety, mainly of somatic kind, seems to be the most regularly sensitive symptom. Results are in some cases better than those obtained with bensodiazepines, but without their side effects: drowsiness, alcohol's interaction, etc.. Symptomatic changes were evaluated using the Hamilton rating scale for anxiety, and statistical analysis of scores was performed. In this study no psychotic patient was included. In previous trials of beta-blockers the author pointed out some positives changes in anxious psychotics.
D001008:Anxiety Disorders / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003975:Diazepam / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010096:Oxprenolol / Q000009:adverse effects / Q000627:therapeutic use*
D010096:Oxprenolol; D003975:Diazepam
Essai en double aveugle (oxprénolol/diazépam) dans l'anxiété.