Dietary manipulation of prostaglandin and thromboxane synthesis in heart, aorta and blood platelets of the rat.
We conclude that dietary changes can have a profound influence on prostaglandin and thromboxane synthesis of organ systems. A better insight into underlying mechanisms is necessary before more definite advice with respect to feeding a linolenic acid and very long-chain polyunsaturated fatty acids as found in fish oils can be given.
D000818:Animals; D001011:Aorta / Q000378:metabolism*; D001792:Blood Platelets / Q000378:metabolism*; D003060:Cod Liver Oil / Q000378:metabolism; D004041:Dietary Fats / Q000378:metabolism*; D011464:Epoprostenol / Q000096:biosynthesis; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D008041:Linoleic Acids / Q000378:metabolism; D008042:Linolenic Acids / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011453:Prostaglandins / Q000096:biosynthesis*; D011460:Prostaglandins F / Q000096:biosynthesis; D051381:Rats; D013931:Thromboxanes / Q000096:biosynthesis*
D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated; D008041:Linoleic Acids; D008042:Linolenic Acids; D011453:Prostaglandins; D011460:Prostaglandins F; D013931:Thromboxanes; D008315:Malondialdehyde; D003060:Cod Liver Oil; D011464:Epoprostenol