["Beat to beat" variations in diabetic patients].
Our aim is to find a way to test the autonomic nervous dysfunction in diabetes mellitus by performing maximal deep-breathings during ECg recording. The subjects underwent ECG recording continously for 2 minutes: during the first minute they breathed regularly, in the second minute they accomplished 6 maximal deep breathings. The R-R intervals in the 1st, as well as the shortest R-R intervals during inspiration and the longest ones during expiration in the second minute were measured and expiration-inspiration ratio (E:I ratio) was calculated. A decreased variation of the R-R intervals from deep-breathings reveals the autonomic nervouis dysfunction . Our data suggest that in diabetes mellitus, R-R intervals show a decreased variation, able to demonstrate earlier autonomic neuropathy.
D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology*; D003920:Diabetes Mellitus / Q000628:therapy; D003929:Diabetic Neuropathies / Q000175:diagnosis*; D003927:Diet, Diabetic; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests
D007004:Hypoglycemic Agents; D007328:Insulin
Variazioni del "Beat to Beat" in pazienti diabetici.