Guanfacine and glucose metabolism.
1. The effect of a single dose of guanfacine 1.0 mg intravenously on glucose metabolism was compared with placebo. Six men participated in the cross-over study. 2. An oral glucose tolerance test was performed 90 min after the administration of the medicaments. Guanfacine had no effect on blood glucose, insulin or the 'Insulinogenic index'.
D000959:Antihypertensive Agents / Q000494:pharmacology*; D001786:Blood Glucose / Q000378:metabolism*; D016316:Guanfacine; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D010648:Phenylacetates / Q000494:pharmacology*
D000959:Antihypertensive Agents; D001786:Blood Glucose; D006146:Guanidines; D007328:Insulin; D010648:Phenylacetates; D016316:Guanfacine