Spongiform encephalopathy of long duration: a family study.
Seven members of a family succumbed to prolonged dementing illnesses. In two, those dementia lasted 10 years, spongiform encephalopathy was found at autopsy. This duration of illness has not been a feature in other instances of familial Creutzfeldt-Jakob disease.
D000328:Adult; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000235:genetics; D003704:Dementia / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome