OmpC and LamB proteins can serve as substitute receptors for host range mutants of coliphage TuIa.
Coliphage TuIa, which uses the OmpF protein as a receptor, can adapt by mutation to using instead the OmpC or LamB protein, or both. Most of the phage mutants retained the ability to use the OmpF protein, when present, but one class of mutants lost this ability and could only use the OmpC protein.
D000327:Adsorption; D001426:Bacterial Proteins / Q000378:metabolism*; D003090:Coliphages / Q000235:genetics / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism; D005814:Genes, Viral; D009154:Mutation; D011991:Receptors, Virus / Q000378:metabolism*
D001426:Bacterial Proteins; D011991:Receptors, Virus