Enhanced fusion capacity of malaria (Plasmodium berghei)-infected mouse red cells.
The capacity of normal and malaria-infected mouse red cells to undergo fusion was investigated by phase contrast microscopy. The fusion of mouse red cells induced by 50% w/w poly(ethylene glycol)-6000 in the presence of Ca+2 is enhanced by P. berghei infection. Cells carrying parasites in the ring form stage and early trophozoite stage show slightly higher fusion induced by dimethyl sulphoxide and Ca+2 than those carrying parasites in trophozoite and schizont stages.
D000818:Animals; D002118:Calcium / Q000097:blood; D002459:Cell Fusion / Q000187:drug effects; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism / Q000469:parasitology / Q000473:pathology*; D066298:In Vitro Techniques; D008288:Malaria / Q000097:blood*; D051379:Mice; D010962:Plasmodium berghei; D011092:Polyethylene Glycols / Q000494:pharmacology
D011092:Polyethylene Glycols; D002118:Calcium; D004121:Dimethyl Sulfoxide