Podophyllin 10% and 25% in the treatment of ano-genital warts. A comparative double-blind study.
One hundred and forty male patients with ano-genital warts were randomly allocated to a double-blind study of 10% and 25% podophyllin in tincture of benzoin compound. One hundred and nine patients attended for a three-month period of surveillance. Only 24 (22%) patients were free of warts after having podophyllin treatment alone, 12 each after treatment with 10% and 25% podophyllin. There was no significant difference in the number of applications needed with each treatment. Neither hypersensitivity nor chemical ulceration occurred.
D001004:Anus Diseases / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005832:Genital Diseases, Male / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011033:Podophyllin / Q000627:therapeutic use*; D011897:Random Allocation; D014860:Warts / Q000188:drug therapy*
D011033:Podophyllin