Minimal deviation melanoma with epidermotropic metastases arising in a congenital nevus.
A congenital nevus removed from a 20-year-old woman was found to contain a minimum deviation melanoma. Subsequently, there were multiple nodular recurrences in the region of the excision as well as in the grafted skin. Microscopically the recurrent lesions closely resembled the original nevus, including the junctional activity and even the grafted skin. Lymph node metastasis occurred 5 1/2 years after excision of the nevus. This is the first report of a minimal deviation melanoma arising in a congenital nevus with epidermotropic metastases.
D000328:Adult; D004817:Epidermis / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000473:pathology* / Q000556:secondary / Q000648:ultrastructure; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009506:Nevus / Q000151:congenital* / Q000473:pathology / Q000556:secondary; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary* / Q000648:ultrastructure; D016038:Skin Transplantation; D014182:Transplantation, Autologous