title: Effect of LH-RH, gonadotrophins or sex hormones on protein synthesis in hypothalamus and pituitaryof immature female rat in vitro.
abstract: Protein synthesis in cerebral cortex, hypothalamus and pituitary of immature female rats was studied after treatment with 5 doses of LH-RH, gonadotrophins or sex hormones. None of the hormonal doses affected protein synthesis in cortex. Sex hormones and gonadotrophins increased protein synthesis in hypothalamus. These effects are attributed to positive feed-backs of these hormone on immature female rat hypothalamus. All treatments increased protein synthesis in pituitary. The direct effect of LH-RH on pituitary and the feed-back effect of sex hormones or gonadotrophins are compared and discussed.
mesh_terms: D000818:Animals; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D006062:Gonadotropins / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D066298:In Vitro Techniques; D014176:Protein Biosynthesis; D051381:Rats
chemical_list: D012739:Gonadal Steroid Hormones; D006062:Gonadotropins; D007987:Gonadotropin-Releasing Hormone