title: Dna repair pathways.
abstract: Our knowledge about DNA repair mechanisms in mammalian cells is reviewed. Ways of measuring excision repair are summarized, and various modes of excision repair are described in terms of mechanisms that yield patch sizes of 0, 1, and few (short patch), and many (long patch) bases. The biological and molecular ways of measuring the effects of replication on a damaged template are presented, as are various models of postreplication repair.
mesh_terms: D000818:Animals; D004247:DNA / Q000378:metabolism / Q000528:radiation effects; D004260:DNA Repair; D004261:DNA Replication; D004279:DNA, Viral / Q000378:metabolism / Q000528:radiation effects; D005057:Eukaryotic Cells / Q000378:metabolism / Q000528:radiation effects; D008957:Models, Genetic; D011740:Pyrimidine Dimers / Q000378:metabolism; D013698:Templates, Genetic; D014466:Ultraviolet Rays
chemical_list: D004279:DNA, Viral; D011740:Pyrimidine Dimers; D004247:DNA