title: Viability of Salmonella typhimurium in metabisulphite-treated bone meal: effect of inocula and moisture variation on the lethal potency of metabisulphite.
abstract: The susceptibility of different inocula of Salmonella typhimurium to the antimicrobial action of various concentrations of metabisulphite in rehydrated bone meal has been investigated. Furthermore, the lethal potency of metabisulphite in the presence of various metabisulphite and moisture concentrations has been examined. It has been shown that the lethal potency of metabisulphite was dependent upon the inocula used in the simulated contamination and the moisture content of the bone meal. A study of the longevity of the potency of metabisulphite has revealed that such a potency could be maintained without a decrease in efficacy for 14--28 days depending on the metabisulphite level in the bone meal.
mesh_terms: D000821:Animal Feed; D001842:Bone and Bones; D004305:Dose-Response Relationship, Drug; D005506:Food Contamination; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000254:growth & development; D012964:Sodium / Q000494:pharmacology; D013447:Sulfites / Q000494:pharmacology*; D013997:Time Factors; D014867:Water
chemical_list: D013447:Sulfites; D014867:Water; C005200:sodium metabisulfite; D012964:Sodium