[Idiopathic orthostatic hypotension and the Shy-Drager syndrome: hemodynamic and pharmacological studies in seven patients (author's transl)].
Idiopathic orthostatic hypotension (IOH) is a slowly progressive disease of the autonomic nervous system. The association of central lesions with those of IOH is characteristic of the Shy-Drager syndrome, which follows a rapidly unfavorable course, and can be distinguished from IOH, according to some authors, by anatomical and pharmacological features. Hemodynamic and pharmacological studies were conducted in 4 cases of IOH and 3 cases of the Shy-Drager syndrome in order to determine the localization and extent of the orthostatic regulatory disorder. No differences were found between the two groups and a common physiopathological mechanism for the two affections is suggested.
D000328:Adult; D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000150:complications*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008722:Methods; D008875:Middle Aged; D012083:Renin / Q000097:blood; D012791:Shy-Drager Syndrome / Q000150:complications* / Q000175:diagnosis; D014636:Valsalva Maneuver
D012083:Renin
Hypotension orthostatique idiopathique et syndrome de Shy-Drager. Etudes hémodynamiques et pharmacodynamiques chez sept sujets. Limites nosologiques.