[Kinetics of radioactive thallium chloride (201TlCl3) transport from the blood to myocardial tissue normally and in cardiac ischemia].
Extraction of 201TlCl3 diffusing into the heart tissue under conditions of its normal functioning and in the presence of ischemia was appraised on a model with isolated coronary perfusion of the myocardium by the dual-tracer method. From analysis of the discharge curve of the tracers used it is concluded whether or not microcirculation of the perfused area of the heart is uniform or heterogeneous. It was established that in myocardial ischemia, 201TlCl3 does not accumulate in the interstitium, which makes it possible to evaluate the zones with diminished inclusion of 201TlCl3 encountered in scanning of the heart as corresponding to diminished blood supply.
D000818:Animals; D001692:Biological Transport; D003327:Coronary Disease / Q000378:metabolism*; D004285:Dogs; D004562:Electrocardiography; D007700:Kinetics; D009206:Myocardium / Q000378:metabolism*; D011865:Radioisotope Dilution Technique; D011868:Radioisotopes; D012711:Serum Albumin, Radio-Iodinated; D013793:Thallium / Q000378:metabolism*
D011868:Radioisotopes; D012711:Serum Albumin, Radio-Iodinated; D013793:Thallium
Kinetika transporta radioaktivnogo khlorida talliia (201TlCl3) iz krovi v tkan' miokarda v norme i pri ishemii serdtsa.