Changes in body temperature after administration of adrenergic and serotonergic agents and related drugs including antidepressants.
This survey, the third in a series, presents extensive tabulations of literature, primarily since 1965, on thermoregulatory effects of adrenergic and serotonergic agonists and their antagonists including ergot alkaloids, amphetamines, tryptamines, monoamine oxidase inhibitors, tricyclic and other antidepressants, a variety of other agents which alter presynaptic aminergic mechanisms including reserpine, 6-hydroxydopamine, p-chlorophenylalanine, alpha-methyltyrosines, cocaine, guanethidine and bretylium. The information listed includes the species used, route of administration and dose of drug, the environmental temperature at which the experiments were performed, the number of tests, the direction and magnitude of body temperature change and remarks on the presence of special conditions, such as age or lesions, or on the influence of other drugs, such as antagonists, on the response to the primary drug.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001679:Biogenic Amines / Q000502:physiology; D001831:Body Temperature / Q000187:drug effects*; D005277:Fenfluramine / Q000494:pharmacology; D006801:Humans; D008774:Methylphenidate / Q000494:pharmacology; D011814:Quipazine / Q000494:pharmacology; D012701:Serotonin / Q000502:physiology*; D012702:Serotonin Antagonists / Q000494:pharmacology; D013566:Sympathomimetics / Q000494:pharmacology*; D014363:Tryptamines / Q000494:pharmacology
D000928:Antidepressive Agents; D001679:Biogenic Amines; D012702:Serotonin Antagonists; D013566:Sympathomimetics; D014363:Tryptamines; D008774:Methylphenidate; D005277:Fenfluramine; D012701:Serotonin; D011814:Quipazine; D000661:Amphetamine