Clinical trial of amitriptyline and fluphenazine in diabetic peripheral neuropathy.
Ten adult insulin-dependent diabetics with symptomatic peripheral neuropathy were treated with amitriptyline alone or in combination with fluphenazine hydrochloride. Nine of the subjects had a good result within 48 to 72 hours. Two patients reacted adversely to the medication. These medications appear effective in treating the discomfort associated with diabetic peripheral neuropathy.
D000639:Amitriptyline / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003929:Diabetic Neuropathies / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005476:Fluphenazine / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans
D000639:Amitriptyline; D005476:Fluphenazine