[Insulin receptors in the HL60 human promyelocytic leukemic cells line].
The insulin binding characteristics of human promyelocitic HL60 cell line was studied by the use pf I(125) insulin. The binding activity was found to increase linearily both with the number of cells and with the incubation time. The competition curve with increasing concentration of unlabeled insulin demonstrated of specific receptors. The number of receptors was estimated to be 6.36 . 10(6) per cell.
D002460:Cell Line; D006098:Granulocytes / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D007700:Kinetics; D007951:Leukemia, Myeloid / Q000378:metabolism*; D011972:Receptor, Insulin / Q000378:metabolism
D007328:Insulin; D011972:Receptor, Insulin
Recettori insulinici nelle cellule della linea promielocitaria umana HL60.