Effect of LH-RH, gonadotrophins or sex hormones on protein synthesis in hypothalamus and pituitaryof immature female rat in vitro.
Protein synthesis in cerebral cortex, hypothalamus and pituitary of immature female rats was studied after treatment with 5 doses of LH-RH, gonadotrophins or sex hormones. None of the hormonal doses affected protein synthesis in cortex. Sex hormones and gonadotrophins increased protein synthesis in hypothalamus. These effects are attributed to positive feed-backs of these hormone on immature female rat hypothalamus. All treatments increased protein synthesis in pituitary. The direct effect of LH-RH on pituitary and the feed-back effect of sex hormones or gonadotrophins are compared and discussed.
D000818:Animals; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D006062:Gonadotropins / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D066298:In Vitro Techniques; D014176:Protein Biosynthesis; D051381:Rats
D012739:Gonadal Steroid Hormones; D006062:Gonadotropins; D007987:Gonadotropin-Releasing Hormone