Avoidance of surgical hyperglycemia in diabetic patients.
Strict intraoperative glucose level control was accomplished with constant low-dose glucose infusion of 100 mg/kg/hr and variable infusion rates of insulin to control serum glucose levels as follows: 20 units/hr for serum glucose levels greater than 200 mg/dL, 1 unit/hr for levels between 80 and 200 mg/dL, and no insulin for levels less than 80 mg/dL. Using this technique, eight diabetic patients with serum glucose levels greater than 250 mg/dL before surgery had their serum glocose levels brought rapidly under control (ie, glucose level less than 200 mg/dL), which continued postoperatively.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D048909:Diabetes Complications; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control*; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000517:prevention & control; D007328:Insulin / Q000008:administration & dosage; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care; D012306:Risk; D013514:Surgical Procedures, Operative / Q000009:adverse effects*
D001786:Blood Glucose; D007328:Insulin; D005947:Glucose