Efficacy of orally administered salbutamol and theophylline in pre-schoolchildren with asthma.
Oral administration of salbutamol and theophylline has been shown to be effective in relieving bronchoconstriction in asthmatic children aged between 3 and 5 years. Changes in respiratory function were monitored using a Wright's low range peak flow meter and a modification of the forced oscillation technique. A combination of both drugs in half doses was as effective as either alone. Nebulised salbutamol produced considerable further improvement in lung function.
D000284:Administration, Oral; D000403:Airway Resistance / Q000187:drug effects; D000420:Albuterol / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D010366:Peak Expiratory Flow Rate; D013806:Theophylline / Q000008:administration & dosage / Q000627:therapeutic use*
D013806:Theophylline; D000420:Albuterol