The value of intraoperative antibiotics in preventing renal transplant wound infections.
In a 3-year period 179 renal transplant operations were performed, during which time a uniform regimen for preventing wound infections was used. The incidence of primary renal transplant wound infections was reduced to 1 per cent by administering a single high dose of broad-spectrum antibiotics intraoperatively as an adjunct to this regimen. Intraoperative antibiotic coverage has been a safe and effective measure for preventing primary transplant wound infections.
D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002102:Cadaver; D002981:Clindamycin / Q000627:therapeutic use; D006801:Humans; D007430:Intraoperative Care; D016030:Kidney Transplantation; D009254:Nafcillin / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014019:Tissue Donors; D014031:Tobramycin / Q000627:therapeutic use; D014184:Transplantation, Homologous
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D009254:Nafcillin; D000667:Ampicillin; D014031:Tobramycin