title: Disabling errors of skin keratinization. Ichthyosiform erythrodermas and the 'half-baby syndrome' treated with an aromatic retinoid.
abstract: The congenital ichthyosiform erythrodermas have become readily treatable with an aromatic retinoid. Satisfactory initial results over the first few months of treatment were achieved when the new preparation was given to Transvaal patients known to have these disorders and hitherto treated in vain. The pharmacology of the drug and therapeutic experiences in 6 cases are described.
mesh_terms: D000328:Adult; D002648:Child; D005050:Etretinate / Q000008:administration & dosage* / Q000009:adverse effects / Q000378:metabolism; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D012867:Skin / Q000187:drug effects; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy* / Q000473:pathology; D014212:Tretinoin / Q000031:analogs & derivatives*
chemical_list: D014212:Tretinoin; D005050:Etretinate