Genetic effects of vinylcyclohexene diepoxide in yeast.
Using D7 strain of S. cerevisiae where we can consider three genetic effects such as mitotic gene conversion, mitotic cross over and reverse mutation we tested vinylcyclohexene diepoxide "in vitro" without metabolic activation. In this condition VCD is very toxic and induces both three genetic effects namely mitotic gene conversion, mitotic cross over and reverse mutation.
D003434:Crossing Over, Genetic / Q000187:drug effects; D003510:Cyclohexanes / Q000009:adverse effects*; D005785:Gene Conversion / Q000187:drug effects; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics; D014753:Vinyl Compounds / Q000009:adverse effects*
D003510:Cyclohexanes; D014753:Vinyl Compounds