[Plasma catecholamines, insulin and glucose in the postoperative phase. Cause and duration of the post-stress syndrome after abdominal surgery].
Plasma catecholamine, insulin secretion, and serum glucose levels were measured to determine the extent and duration of the postaggression syndrome following major abdominal surgery: 1. There was a significant increase in plasma catecholamine levels (epinephrine and norepinephrine) during the first postoperative week. -2. Glucose dependent insulin secretion remained elevated for more than 6 days following major abdominal surgery. -3. Postoperative glucose assimilation was reduced for more than 1 week. -4. There is a negative correlation between plasma catecholamine levels and reduced insulin secretion following the administration of glucose in the postoperative phase. -5. Inhibition of insulin secretion should be included in the therapeutic considerations for the first postoperative week in all patients undergoing major abdominal surgery.
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D004837:Epinephrine / Q000097:blood*; D005260:Female; D005767:Gastrointestinal Diseases / Q000601:surgery*; D005770:Gastrointestinal Neoplasms / Q000601:surgery; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D011183:Postoperative Complications / Q000097:blood*; D013312:Stress, Physiological / Q000503:physiopathology*
D001786:Blood Glucose; D007328:Insulin; D009638:Norepinephrine; D004837:Epinephrine
Plasmacatecholamine, Insulin und Glucose in der postoperativen Phase. Untersuchungen zur Ursache und Dauer des Postaggressionssyndroms nach Bauchoperationen.