title: [Incidence of immune reactions following penetrating keratoplasty (report on 100 consecutive interventions) (author's transl)].
abstract: The outcome of 100 consecutive penetrating keratoplasties was investigated. At present, inadequate surgical technique does not appear to be the major cause of graft failure; instead, immunologic reactions are largely responsible for graft failure. Taking corneal disease and the degree of vascularization as criteria, the prognosis was judged to be favourable in 38 of the 100 keratoplasties, less favorable in 56, and poor in six. In the first group, graft failure occurred only five times (about 13%), whereas in the second group graft reactions of variable degrees were found in about 64%. As expected, the group with a poor prognosis showed the poorest results. Postoperative follow-up over a long period of time and adequate local steroid therapy are necessary.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003315:Cornea / Q000098:blood supply; D016039:Corneal Transplantation; D005260:Female; D005500:Follow-Up Studies; D006087:Graft vs Host Reaction; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D014181:Transplantation Immunology; D014184:Transplantation, Homologous
vernacular_title: Die Häufigkeit von Immunreaktionen nach perforierenden Keratoplastiken. Bericht über 100 aufeinanderfolgende Eingriffe.