Immunofluorescent studies in filariasis: antibody levels in rats infected with the Malayan forest filaria, Breinlia booliati.
Antibody levels were investigated in rats infected with Breinlia booliati using the indirect immunofluorescent antibody technique. Sonicated antigens were prepared from microfilariae and adult worms. Adult worm antigen was rather unsatisfactory. The sonicated microfilarial antigen was useful in detecting antibodies in various groups of rat sera. Very high antibody levels were seen in amicrofilaraemic rats harbouring unisexual infections or varying worm loads. The significance of these observations are discussed.
D000818:Animals; D000906:Antibodies / Q000032:analysis*; D005260:Female; D005368:Filariasis / Q000097:blood / Q000276:immunology*; D005370:Filarioidea / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D008297:Male; D051381:Rats
D000906:Antibodies