Inhibitory effect of 5-bromo-6-azauracil on growth and cell division of Saccharomyces cerevisiae.
The most marked effect of 5-bromo-6-azauracil (BrAzU) on yeast cells is to cause cell lysis. The inhibition of the lytic process is delayed and this delay coincides in time with the capacity of preformed pyrimidines to reverse the effect of BrAzU.
D000963:Antimetabolites / Q000494:pharmacology; D001976:Bromouracil / Q000031:analogs & derivatives* / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007700:Kinetics; D011743:Pyrimidines / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects*
D000963:Antimetabolites; D011743:Pyrimidines; C029228:5-bromo-6-azauracil; D001976:Bromouracil