The effectiveness of antihistamines in the common cold.
A randomized, double-blind, placebo-controlled study was done on 106 volunteers to assess the effectiveness of chlorpheniramine maleate against the common cold. The results suggest that this antihistamine is significantly effective in relieving the symptoms of a cold if used four times daily for one week, and that relief was gained with no significant increase in side effects.
D000328:Adult; D002744:Chlorpheniramine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003139:Common Cold / Q000150:complications / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D012894:Sleep Stages / Q000187:drug effects; D012907:Smoking
D002744:Chlorpheniramine