Ornidazole in the prevention of infections after abdominal hysterectomy.
Following informed consent, 226 consecutive patients scheduled to undergo abdominal hysterectomy entered a randomized double-blind clinical trial to determine the efficacy of ornidazole versus placebo in the prevention of postoperative infections. Postoperative abscesses occurred in 2 patients (1.8%) in the ornidazole group compared to 5 patients (4.4% in the placebo group. Febrile episodes occurred in 6 patients (5.3% receiving ornidazole and in 13 patients (11.4%) receiving placebo.
D000038:Abscess / Q000517:prevention & control; D001424:Bacterial Infections / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009593:Nitroimidazoles / Q000627:therapeutic use*; D009950:Ornidazole / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control*; D011897:Random Allocation
D009593:Nitroimidazoles; D009950:Ornidazole