title: Quantitation of the interaction of EScherichia coli RNA polymerase holoenzyme with double-helical DNA using a thermodynamically rigorous centrifugation method.
mesh_terms: D001665:Binding Sites; D004279:DNA, Viral; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D004926:Escherichia coli / Q000201:enzymology*; D006493:Heparin / Q000494:pharmacology; D007700:Kinetics; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D013816:Thermodynamics; D014461:Ultracentrifugation / Q000379:methods
chemical_list: D004279:DNA, Viral; D006493:Heparin; D012321:DNA-Directed RNA Polymerases