title: [Menstrual cycle changes during consecutive artificial insemination therapy and their treatment].
abstract: Emotional stress-induced problems generated by the application of artificial insemination therapy by donor (AID) are considerable. After 6 months of frustrane insemination treatment, 54% of the women exhibited irregular or anovulatory cycles. Especially the persistent late ovulation often leads to a failure of the mechanisms of conception. An early ovulation timing with high dosages of synthetic LH-releasing hormone or a stimulating LH-RH-analogue (HOE 766) lead to an increasing pregnancy rate after application in the third insemination cycle from 34,0% untreated to 51,1% treated. The early application of ovulation inducing or timing substances is underlined in a program of artificial insemination therapy to eliminate possible stress-induced failures at an early point of treatment. As the spontaneous pregnancy rate is high in the first treatment cycles, LH-RH or its analogue should be administered after two frustrane insemination cycles.
mesh_terms: D001007:Anxiety; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use*; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D007315:Insemination, Artificial / Q000009:adverse effects*; D008599:Menstruation Disturbances / Q000188:drug therapy* / Q000209:etiology; D011247:Pregnancy; D013315:Stress, Psychological / Q000150:complications
chemical_list: D006728:Hormones; D007987:Gonadotropin-Releasing Hormone
vernacular_title: Zyklusstörungen während konsekutiver artefizieller Inseminationstherapie und ihre Behandlung.