title: Prophylactic use of metronidazole in preventing wound sepsis after elective cholecystectomy.
abstract: The effect of intravenous metronidazole as prophylaxis against postoperative wound infection was studied in a prospective, randomized, double-blind controlled trial of 116 patients undergoing elective cholecystectomy. No significant difference was found in the infection rate between the treated and the control groups.
mesh_terms: D000368:Aged; D001419:Bacteria / Q000302:isolation & purification; D001646:Bile / Q000382:microbiology; D002763:Cholecystectomy; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D011897:Random Allocation; D012306:Risk; D018805:Sepsis / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D008795:Metronidazole