title: Lupus erythematosus.
abstract: Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been emphasized. Management of the LE patient, including appropriate diagnostic studies and therapy relevant to the dermatologist, is discussed in the review.
mesh_terms: D000936:Antigen-Antibody Complex; D002921:Cicatrix / Q000209:etiology; D003165:Complement System Proteins / Q000172:deficiency; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000628:therapy; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000628:therapy; D008297:Male; D010201:Panniculitis, Nodular Nonsuppurative / Q000175:diagnosis; D011164:Porphyrias / Q000175:diagnosis; D012867:Skin / Q000473:pathology; D014466:Ultraviolet Rays / Q000009:adverse effects; D014657:Vasculitis / Q000276:immunology; D014777:Virus Diseases / Q000150:complications
chemical_list: D000936:Antigen-Antibody Complex; D003165:Complement System Proteins