[Analysis of results in studies on anti-erythrocyte auto-sensitization in 2400 patients].
The authors report their experience since 1970 in the laboratory investigation of anti-erythrocyte auto-immunization. 2400 tests were performed, and the positive results were divided into 2 groups: --341 patients with a positive direct antiglobulin test; --502 patients without positive direct antiglobulin test, but with various abnormalities: positive elution, increased titer of cold agglutinin, auto-agglutinability of protease treated red cells... The immunohaematological and etiological data are described for each group. It appears: --that there is no significant difference in etiological data between the two groups; --that the direct antiglobulin test is not sufficient in investigation of anti-erythrocyte auto-immunization, but some other immunohaematologic tests are indispensable.
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis*; D001323:Autoantibodies / Q000302:isolation & purification*; D003080:Cold Temperature; D003165:Complement System Proteins / Q000276:immunology; D003298:Coombs Test; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007158:Immunologic Techniques
D001323:Autoantibodies; D007074:Immunoglobulin G; D003165:Complement System Proteins
Analyse des résultats observés au cours de la recherche d'une auto-sensibilisation anti-érythrocytaire chez 2400 malades.