[The influence of prostacyclin on gastrointestinal blood flow during hypovolemic shock (author's transl)].
The influence of a continuous PGI 2 infusion on blood flow of various organs was tested in normovolemia and in hemorrhagic shock. PGI 2 increased the blood flow of stomach, pancreas and jejunum in normovolemic animals. The reduced blood flow due to hemorrhagic shock was increased to preshock values in stomach, pancreas, and jejunum. A linear correlation was found between the dose of PGI 2 and mucosal blood flow of the stomach.
D000818:Animals; D004064:Digestive System / Q000098:blood supply*; D011464:Epoprostenol / Q000494:pharmacology*; D011453:Prostaglandins / Q000494:pharmacology*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects; D012769:Shock / Q000503:physiopathology*
D011453:Prostaglandins; D011464:Epoprostenol
Wirkung von Prostacyclin auf die gastrointestinale Durchblutung im hypovolämischen Schock.