Comparison of cephazolin and gentamicin in the prophylactic treatment of infection in out-patient urinary tract endoscopy.
Previous studies have shown that the incidence of rigors following urinary tract endoscopy in out-patients may be as high as 16% and that this incidence can be significantly lowered to about 7% by the administration of intramuscular cephazolin sodium at the time of endoscopy. In order to reduce further the rigor rate, a comparison of intramuscular cephazolin with gentamicin has been carried out with 200 patients in each group. There was a rigor rate correlation between an infected urine and the occurrence of a rigor. Cephazolin sodium remains the drug of choice in this situation because of its low toxicity.
D002437:Cefazolin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003558:Cystoscopy; D004311:Double-Blind Method; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D014552:Urinary Tract Infections / Q000517:prevention & control*
D005839:Gentamicins; D002437:Cefazolin