[Effect of various endotoxin doses on an isolated and extramurally denervated jejunal loop of the dog].
The author examined the role of extramural nervous system in the pathogenesis of the inhibited jejunal motorics under the influence of different doses of endotoxin. He used nonanesthezid dogs with extramuraly denervated loop, prepared from the jejunum in advance by the method of Babkin. The recordings were made by an insertion of a baloon. The motor activity of the loop was inhibited, which did not differ significantly from the inhibition of the normally inervated loop. Our results showed that the extramural nervous system did not play significant role in the inhibition of the jejunal motorics under the influence of endotoxin.
D000818:Animals; D003714:Denervation; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004731:Endotoxins / Q000008:administration & dosage*; D004926:Escherichia coli; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D066298:In Vitro Techniques; D007583:Jejunum / Q000187:drug effects*; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects
D004731:Endotoxins
Vliianie na razlichni dozi endotoksin vŭrkhy izolirana i ekstramuralno denervirana brimka ot ĭeiunuma na kucheta.