Selective migration of T-cell subset in pleural fluid from non-Hodgkin's lymphoma.
Pleural fluid from a patient with non-Hodgkin's lymphoma was examined for lymphocyte subpopulations and their proliferative response to PHA, Con A, and PWM. T lymphocytes were present in a high proportion; in contrast only few B lymphocytes were present when compared to peripheral blood T and B lymphocytes. Among T-cell subsets, Tmu cells were present in high numbers. By contrast Tgamma cells were lacking. Proliferative response to PHA and Con A were normal; however, PWM-induced proliferation was subnormal. This study demonstrates selective migration of a subset of T cells in pleural fluid.
D000293:Adolescent; D002464:Cell Migration Inhibition; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation; D016403:Lymphoma, Large B-Cell, Diffuse / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D010996:Pleural Effusion / Q000276:immunology*; D011043:Pokeweed Mitogens / Q000494:pharmacology; D013601:T-Lymphocytes / Q000145:classification*
D010835:Phytohemagglutinins; D011043:Pokeweed Mitogens; D003208:Concanavalin A