title: [Resuscitation in the treatment of severe tetanus: clinical experiences].
abstract: Following a brief review of the aetiopathogenesis, symptomatology and treatment of tetanus infection, a personal series of 31 patients (14 males and 17 females aged between 26 and 89) is considered. The patients were admitted between May 1970 and May 1978 to the Alessandria Civil Hospital Resuscitation workers, it is shown that mortality from tetanus increases steadily with the increasing age of patients. It is also observed that the introduction of Ossime therapy has reduced curarizing drugs. As a result of the cholinesterase-restoring effect of Ossime, a normalization in the transit of inhibitor stimuli on muscle tone and hence a reduction in hypertone is hypothesized.
mesh_terms: D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000328:Adult; D000368:Aged; D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D002801:Cholinesterase Reactivators / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007116:Immunization, Passive / Q000379:methods; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D012138:Respiratory Therapy / Q000379:methods; D012151:Resuscitation / Q000379:methods*; D013742:Tetanus / Q000628:therapy*; D013745:Tetanus Toxoid / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D002801:Cholinesterase Reactivators; D013745:Tetanus Toxoid; D000109:Acetylcholine
vernacular_title: La rianimazione nel trattamento del tetano grave; esperienze cliniche.