The origin of hemopoietic cells in ectopic implants of spleen and marrow.
Spleen and marrow tissues were cross-transplanted between CBA and CBA/HT6 mice. The majority of karyotypes in the regenerated implants were of recipient origin indicating that these implants are chimeric structures with the stroma of donor origin providing a framework for the proliferation of the recipient's hemopoietic stem cell.
D000818:Animals; D016026:Bone Marrow Transplantation; D005260:Female; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D007621:Karyotyping; D008677:Metaphase; D051379:Mice; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D013154:Spleen / Q000637:transplantation*; D014185:Transplantation, Isogeneic