A double-blind comparison of parenteral dipyrone and pethidine in the treatment of post-operative pain.
A double-blind trial was carried out in 100 patients with moderate to severe post-operative pain to compare the analgesic effectiveness over a 6-hour period of single intramuscular injections of 2.5 g dipyrone and 100 mg pethidine. Maximum pain relief was seen 2 hours after drug administration in both groups and there was no statistically significant difference in responses. No side-effects were reported.
D000328:Adult; D000632:Aminopyrine / Q000031:analogs & derivatives*; D002986:Clinical Trials as Topic; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008614:Meperidine / Q000627:therapeutic use*; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*
D000632:Aminopyrine; D004177:Dipyrone; D008614:Meperidine