[Interrelation between gastrin and insulin in a group of normal subjects].
The insulin secretory action of gastrin during O.G.T.T. has been assessed. The insulinaemic and gastrinaemic curves were evaluated in a group of normal subjects submitted to oral glucose load, using radioimmunological measurement techniques. At a later stage, the insulinaemic values were considered in the same subjects after administration of a gastrin analogue (pentagastrin) by the subcutaneous route in a dose such as to provoke a maximal gastric acid response. The data suggest that any participation of gastrin in the regulation of insulin secretion following a glucose meal can be excluded.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D005755:Gastrins / Q000097:blood*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D010418:Pentagastrin
D001786:Blood Glucose; D005755:Gastrins; D007328:Insulin; D010418:Pentagastrin
Studio delle interrelazioni tra gastrina ed insulina in un gruppo di soggetti normali.