title: Cryptococcus neoformans serotype groups encountered in Oklahoma.
abstract: Eighty clinical and 28 soil isolates of C. neoformans obtained in Oklahoma were separated into A-D and B-C serotype groups utilizing creatinine-dextrose agar with bromthymol blue. Previously, serotype B-C clinical isolates have been frequent only in patients from Southern California where as many as 50% of the isolates are of this type. In contrast, in patients from the rest of the United States the B-C frequency has been only 6%. Of the 80 C. neoformans isolates from Oklahoma patients, 12 (15%) were serotype B-C. One-half of these 12 Oklahoma patients with serotype B-C isolates had no history of any travel to California, and were long-time residents of Oklahoma. All 28 soil isolates of C. neformans from Oklahoma in this study were serotype A-D. Since serotype B-C recovery from a soil sample has never been reported, attempts are in progress to isolate serotype B-C from the environments of these patients from Oklahoma.
mesh_terms: D000328:Adult; D000368:Aged; D001979:Bromthymol Blue; D003404:Creatinine; D003453:Cryptococcosis / Q000453:epidemiology / Q000382:microbiology; D003454:Cryptococcus / Q000145:classification*; D003455:Cryptococcus neoformans / Q000145:classification*; D005260:Female; D005947:Glucose; D006801:Humans; D008297:Male; D008828:Microbiological Techniques; D008875:Middle Aged; D009825:Oklahoma; D012703:Serotyping / Q000379:methods*; D012988:Soil Microbiology
chemical_list: D003404:Creatinine; D005947:Glucose; D001979:Bromthymol Blue