Increase in colony-forming units of Candida albicans after treatment with polyene antibiotics.
Polyene antibiotics, at concentrations which do not cause detectable toxic effect, induce an increase in the number of colon-forming units of yeast cells of Candida albicans. This effect, which we attribute to an increase in plating efficiency, is probably caused by binding of the polyenes to fatty acids in the cell wall of fungi.
D000666:Amphotericin B / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D002473:Cell Wall / Q000187:drug effects; D005227:Fatty Acids / Q000378:metabolism; D011090:Polyenes / Q000378:metabolism / Q000494:pharmacology; D013696:Temperature
D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D011090:Polyenes; D000666:Amphotericin B