Dantrolene sodium suspension in treatment of spastic cerebral palsy.
A double-blind study was carried out on 20 children with spasticity secondary to cerebral palsy, in order to compare the effects of dantrolene sodium suspension and a placebo. The drug was found to be physiologically active in reducing the force of muscle contraction, but objective functional improvement, as measured by multiple performance tests, was irregular and probably not significant.
D000203:Activities of Daily Living; D000284:Administration, Oral; D000293:Adolescent; D002547:Cerebral Palsy / Q000175:diagnosis / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003620:Dantrolene / Q000008:administration & dosage* / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009068:Movement; D009128:Muscle Spasticity / Q000175:diagnosis / Q000188:drug therapy; D013535:Suspensions
D013535:Suspensions; D003620:Dantrolene