The effect of hemolyzed erythrocytes in the virulence of Escherichia coli and of normal human oral flora in a mouse model.
Hemoglobin enhances the virulence of E. coli in the peritoneum. This study investigates the effect of blood on the virulence of E. coli and human oral anaerobes in the mouse neck. E. coli neck infectivity is significantly enhanced by blood. Oral anaerobic infections are not affected.
D000818:Animals; D001769:Blood; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000209:etiology* / Q000401:mortality; D006257:Head / Q000601:surgery; D006461:Hemolysis; D007928:Lethal Dose 50; D051379:Mice; D009055:Mouth / Q000382:microbiology*; D009333:Neck / Q000601:surgery; D013530:Surgical Wound Infection / Q000209:etiology*