Clostridial myonecrosis after resection of skin tumours in an immunosuppressed patient.
This paper reports a case of clostridial myonecrosis (gas gangrene) which occurred in a vegetable gardener receiving immunosuppression therapy with prednisolone and azathioprine for renal allograft preservation. The infection developed after the excision of crusted squamous-cell carcinomata from the dorsum of the hand, the circulation of which was compromised by the presence of a radial artery/cephalic vein arteriovenous fistula. Amputation, followed by treatment with hyperbaric oxygen, was successful.
D000328:Adult; D000671:Amputation, Surgical; D005738:Gas Gangrene / Q000209:etiology* / Q000628:therapy; D006225:Hand; D006801:Humans; D006931:Hyperbaric Oxygenation; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications; D012878:Skin Neoplasms / Q000601:surgery*