[Signification of fibrinogen degradation (FDP) product in CSF during the neonatal period (author's transl)].
Results of a prospective study on neonatal brain damage are reported. 57 full term newborns were subjected to clinical examination with a one year follow-up. Blood and CSF were sampled for FDP determinations on days J1, J3, J8 and when necessary, J15. Traumatic punctures do not alter results. FDP measurement were negative in the whole blood samples and most CSF ones. High FDP values in early samples are linked to brain damage and values above 4 micrograms/ml are significantly correlated to neurological sequelae.
D001925:Brain Damage, Chronic / Q000097:blood / Q000134:cerebrospinal fluid*; D005338:Fibrin Fibrinogen Degradation Products / Q000134:cerebrospinal fluid*; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies
D005338:Fibrin Fibrinogen Degradation Products
Signification de la présence des produits de dégradation de la fibrine et du fibrinogène dans le liquide céphalo-rachidien à la période néonatale.