Calcium and calmodulin in the regulation of blood cell functions (a mini-review).
A great deal of cellular functions are regulated by changes in intracellular calcium concentration. Calmodulin, a low molecular weight cytoplasmic protein is basically involved in this regulation through a calcium-dependent interaction with various enzyme systems. The review discusses the chemical and physiological basis of calcium and calmodulin actions in the cell interior. Describes calcium-regulation of various functions in red cells, platelets and leukocytes.
D001692:Biological Transport; D001773:Blood Cells / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D001792:Blood Platelets / Q000502:physiology; D002118:Calcium / Q000494:pharmacology* / Q000502:physiology; D002135:Calcium-Binding Proteins / Q000494:pharmacology*; D002147:Calmodulin / Q000494:pharmacology* / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D055598:Chemical Phenomena; D002621:Chemistry; D004247:DNA / Q000096:biosynthesis; D004912:Erythrocytes / Q000502:physiology; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D008213:Lymphocyte Activation
D002135:Calcium-Binding Proteins; D002147:Calmodulin; D004247:DNA; D002118:Calcium