Pemphigoid nodularis.
We here report the unusual occurrence of bullous pemphigoid mimicking prurigo nodularis in a 59-year-old woman. Direct immunofluorescence studies of a nodular lesion revealed linear deposition of IgG and C3 at the epidermal basement membrane zone (EBMZ). Indirect immunofluorescence studies of serum revealed IgG pemphigoid antibasement membrane zone antibodies in 1:1,280 titer. This entity can be distinguished from other bullous pemphigoid variants.
D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*