[Treatment of intestinal nematode infections with albendazole. Preliminary results (author's transl)].
A randomized double-blind study, in order to evaluate effectiveness and tolerance of albendazole, was carried out in 186 african subjects presenting intestinal nematode infections in Mali and Senegal. The drug, well tolerated, given as a single dose of 0.4 g (adolescents and adults) or 0.2 g (children) is curative in more than 90% for ascariasis. For ancylostomiasis and trichuriasis, the effectiveness is less satisfactory in children, probably due to insufficient dosage in this age group.
D000293:Adolescent; D000328:Adult; D000368:Aged; D015766:Albendazole; D000724:Ancylostomiasis / Q000188:drug therapy; D000871:Anthelmintics / Q000627:therapeutic use*; D001196:Ascariasis / Q000188:drug therapy; D001562:Benzimidazoles / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy / Q000469:parasitology*; D008297:Male; D008875:Middle Aged; D009349:Nematode Infections / Q000188:drug therapy*; D010270:Parasite Egg Count; D011897:Random Allocation; D014257:Trichuriasis / Q000188:drug therapy
D000871:Anthelmintics; D001562:Benzimidazoles; D015766:Albendazole
Traitement des nématodoses intestinales par l'albendazole. Résultats préliminaires.