A multicenter clinical investigation employing ethinyl estradiol combined with dl-norgestrel as postcoital contraceptive agent.
Six hundred ninety-two women were enrolled in a multicenter clinical trial to evaluate a combination of ethinyl estradiol and dl-norgestrel as a postcoital contraceptive. When compared with various formulas predicting the probability of pregnancy in this group, the number of pregnancies observed appears to be reduced by approximately 84%. The combination of 200 micrograms of ethinyl estradiol and 2 mg of dl-norgestrel seems to be effective as a postcoital contraceptive with several advantages over estrogens alone.
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003277:Contraceptives, Oral, Combined; D003281:Contraceptives, Postcoital; D004997:Ethinyl Estradiol / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008598:Menstruation; D009644:Norgestrel / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*
D003277:Contraceptives, Oral, Combined; D003281:Contraceptives, Postcoital; D009644:Norgestrel; D004997:Ethinyl Estradiol