title: [Megalocytic interstitial nephritis. A contribution to the differential diagnosis of the large insufficient kidney].
abstract: After a female patient had presented with advanced renal failure, bilateral enormous increase in kidney size radiologically, urinary tract infection (E. coli) and septicemia, autopsy disclosed megalocytic interstitial nephritis (MIN). Clinical and pathological differentiation from renal parenchymal malakoplakia (RPM) is discussed. A literature survey of 15 cases of MIN and 35 observations of RPM points to certain differences between the two entities, i.e. an increased incidence of bilateral pathology in MIN, mor frequent extrarenal localizations in RPM, absent Michaelis-Gutmann bodies and a predominantly cortical distribution in MIN. The similarities, however, suggest that the two conditions might represent different stages of one and the same disease process.
mesh_terms: D003937:Diagnosis, Differential; D004927:Escherichia coli Infections / Q000473:pathology; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000175:diagnosis* / Q000473:pathology; D018805:Sepsis / Q000473:pathology
vernacular_title: Grosszellige interstitielle Nephritis. Ein Beitrag zur Differentialdiagnose der grossen insuffizienten Niere.