Modification of photocarcinogenesis by chemical agents.
The evidence is long standing and compelling that chemical agents can modify the carcinogenic effects of light. Various types of chemical-light interaction are discussed, and events in chemical photocarcinogenesis, chemically enhanced photocarcinogenesis, and promotion of photocarcinogenesis are described. Specific examples of each type of process are given, and the importance of interaction of various wavelengths of UV radiation for these processes is stressed.
D000818:Animals; D002273:Carcinogens; D004307:Dose-Response Relationship, Radiation; D008466:Mechlorethamine / Q000633:toxicity; D008730:Methoxsalen / Q000633:toxicity; D009369:Neoplasms / Q000209:etiology* / Q000276:immunology; D010787:Photosensitivity Disorders / Q000150:complications*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014916:Whole-Body Irradiation
D002273:Carcinogens; D008466:Mechlorethamine; D008730:Methoxsalen