title: [Impact of synthetic sexual steroids on blood volume (author's transl)].
abstract: The isotope dilution technique was used to study the oestrogen component of "Deposiston", a long-acting contraceptive, and its effects on blood volume. Blood volume increased by about ten per cent within 15 days from administration of 3 mg of ethinyloestradiol-sulphonate (1 mg/week). Haematocrit was reduced, at the same time. This haemodynamic initial effect should be always taken into account for any assessment of biochemical parameters in response to hormonal contraception.
mesh_terms: D000293:Adolescent; D000328:Adult; D001810:Blood Volume / Q000187:drug effects*; D003276:Contraceptives, Oral / Q000494:pharmacology*; D003277:Contraceptives, Oral, Combined / Q000494:pharmacology*; D004338:Drug Combinations; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives* / Q000494:pharmacology; D005260:Female; D006400:Hematocrit; D006801:Humans; D009640:Norethindrone / Q000494:pharmacology*; D011865:Radioisotope Dilution Technique; D013997:Time Factors
chemical_list: D003276:Contraceptives, Oral; D003277:Contraceptives, Oral, Combined; D004338:Drug Combinations; D004997:Ethinyl Estradiol; C011436:Deposiston; D009640:Norethindrone
vernacular_title: Zum Einfluss synthetischer Sexualsteroide auf das Blutvolumen.