Valine-resistant Escherichia coli K-12 strains with mutations in the ilvB operon.
Escherichia coli K-12 mutants resistant to growth inhibition by valine were isolated. These strains contained mutations in the ilvB operon effecting either the regulation of acetohydroxy acid synthase I or the sensitivity of the enzyme to end product inhibition by valine.
D000095:Acetolactate Synthase / Q000235:genetics* / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D005809:Genes, Regulator; D009154:Mutation; D009876:Operon; D007652:Oxo-Acid-Lyases / Q000235:genetics*; D014633:Valine / Q000494:pharmacology*
D000095:Acetolactate Synthase; D007652:Oxo-Acid-Lyases; D014633:Valine