Treatment of palmoplantar pustulosis with Tigason.
In a double-blind, cross-over trial with Tigason and placebo, the parameters of palmoplantar pustulosis underwent significant changes during the retinoid therapy. A hand-over effect was clearly indicated during the placebo period and several patients experienced long-lasting remissions.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005050:Etretinate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy*; D006229:Hand Dermatoses / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D011701:PUVA Therapy; D012536:Scalp Dermatoses / Q000188:drug therapy; D013492:Suppuration; D014212:Tretinoin / Q000031:analogs & derivatives*
D003879:Dermatologic Agents; D014212:Tretinoin; D005050:Etretinate