title: [Local immunity in acute dysentery. II. The content of antibody-forming cells in the large intestine mucosa in acute Flexner dysentery in the dynamics of the disease].
abstract: Antibody-forming cells were detected in the large intestine of patients with acute Flexner's dysentery by means of the modified Jerne - Nordin method of hemolysis in agar. This method allowed one to determine the classes of immunoglobulins produced by the cells contained in tissue microspecimens obtained by the biopsy of the intestinal mucosa. The maximum amount of antibody-containing cells could be detected on days 7-12 of the disease. The content of antibody-forming cells was shown to depend on the severity of dysentery, the duration of the disease and the therapeutic methods used in the process of treatment. IgA was found to be the most frequent antigen type.
mesh_terms: D000208:Acute Disease; D000921:Antibody-Producing Cells / Q000276:immunology*; D002452:Cell Count; D004405:Dysentery, Bacillary / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007413:Intestinal Mucosa / Q000276:immunology*; D007420:Intestine, Large / Q000276:immunology*; D012763:Shigella flexneri; D013997:Time Factors
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: O mestnom immunitete pri ostroĭ dizenterii. Soobshchenie II. Soderzhanie antiteloobrazuiushchikh kletok v slizistoĭ tolstoĭ kishki u bol'nykh ostroĭ dizenterieĭ Fleksnera v dinamike zabolevaniia.