Prediction of urinary excretion of 131I-orthoiodohippurate.
A new formula is presented for the prediction of urinary excretion at approximately 35 min after injection of 131I-orthoiodohippurate, derived from a large series of normal kidney donors, before and after unilateral nephrectomy, and a few patients with diseases in which there was no evidence of urinary tract obstruction. The best formula was: Expected percent dose excretion at 35 min = 79.3[1-e--(0.004798 X ERPF)] with a standard error of estimate (Sy.x) of 5.2% dose. This value has been particularly useful in clinical practice in the calculation of an excretion index (actual/expected percent dose excretion) which separates various post-transplantation entities and various nephrourologic processes.
D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine; D007668:Kidney / Q000378:metabolism*; D016030:Kidney Transplantation; D008954:Models, Biological; D013997:Time Factors; D014570:Urologic Diseases / Q000378:metabolism*
D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid