[Catecholamine and renin-angiotensin system in blood pressure control in patients with liver cirrhosis].
The changes induced by active tilting in arterial pressure, plasma renin activity, norepinephrine and its precursors phenylalanine and tyrosine were evaluated in 8 patients with liver cirrhosis and 6 healthy controls. The results suggest the inability of the adrenergic system, though hyperstimulated, to maintain arterial pressure homeostasis in cirrhosis with a compensatory hyperactive renin-angiotensin system. Derangements in catecholamine synthesis, possibly due to altered utilisation of precursors to alternative final products (weak neurotransmitters?) can be taken into account.
D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D010649:Phenylalanine / Q000097:blood; D011187:Posture; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System; D014443:Tyrosine / Q000097:blood
D014443:Tyrosine; D010649:Phenylalanine; D012083:Renin; D009638:Norepinephrine
Catecolamine e sistema renina-angiotensina nel controllo della pressione arteriosa in pazienti con cirrosi epatica.