Ibuprofen versus placebo in the relief of post-episiotomy pain.
Thirty post-partum patients, aged 19 to 37 years, were treated for episiotomy pain and inflammation with either 1600 mg ibuprofen (400 mg every 6 hours) or placebo daily for 7 days in a completely randomized, double-blind study. Pain intensity, movement restriction and extent of swelling in the episiotomy were recorded prior to treatment and at intervals of 1, 3, 5 and 7 days. The difference scores of pain intensity, movement restriction and extent of swelling were calculated from the differences between pretreatment and post-treatment values. By all methods of evaluation, ibuprofen was significantly more effective than placebo at 1 and 3 days after the initiation of the treatment. Only 2 minor side-effects were recorded, both in the placebo group.
D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004841:Episiotomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D010919:Placebos; D011247:Pregnancy; D011644:Puerperal Disorders / Q000188:drug therapy*; D011897:Random Allocation
D010919:Placebos; D007052:Ibuprofen