Fluproquazone for osteoarthritis.
Fluproquazone (100 mg t.d.s.) was compared in a double-blind cross-over trial with indomethacin (25 mg t.d.s.) and placebo. Fluproquazone and indomethacin were both superior to placebo. The active drugs were comparable in most measures of efficacy though significantly more patients preferred indomethacin to fluproquazone. Side-effects were few and did not lead to withdrawal of treatment.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010146:Pain / Q000188:drug therapy; D011799:Quinazolines / Q000009:adverse effects / Q000627:therapeutic use*; D052999:Quinazolinones; D011897:Random Allocation
D011799:Quinazolines; D052999:Quinazolinones; C023491:fluproquazone; D007213:Indomethacin