Regulation of the immune response to bacterial lipopolysaccharide by adherent cells.
Immune response to bacterial lipopolysaccharide is usually short lived, but it often reappears without additional stimulus in a cyclic fashion. Activated adherent cells, presumably macrophages, were found to have a role in the reduction of the immune response to Escherichia coli O127 lipopolysaccharide. The suppressive activity of the adherent cells was abrogated before renewal of the responsiveness.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D002351:Carrageenan / Q000494:pharmacology; D005260:Female; D006462:Hemolytic Plaque Technique; D007108:Immune Tolerance; D007114:Immunization; D008070:Lipopolysaccharides / Q000276:immunology*; D008213:Lymphocyte Activation; D008264:Macrophages / Q000276:immunology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008819:Mice, Nude
D000907:Antibodies, Bacterial; D008070:Lipopolysaccharides; D002351:Carrageenan