[Albendazole. Evaluation of tolerance and efficacy in oxyuriasis, trichocephaliasis, ankylostomiasis, ascaridiasis, anguilluliasis].
Albendazole was given to some men for the first time. 131 patients (43 children) received different dosages, without clinical intolerance. Biological parameters were normal. Each study was made in two parts: - determination of the good dosage, - administration in a double-blind study (except for Strongyloides Stercoralis). Albendazole has a good efficiency against Enterobius Vermicularis, Trichuris trichiura, Ascaris lumbricoides and Necator americanus. Strongyloides Stercoralis seems to be killed by this drug, but complementary studies will be necessary.
D000328:Adult; D015766:Albendazole; D000724:Ancylostomiasis / Q000188:drug therapy; D000871:Anthelmintics / Q000009:adverse effects / Q000627:therapeutic use*; D001198:Ascaridiasis / Q000188:drug therapy; D001562:Benzimidazoles / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006801:Humans; D009349:Nematode Infections / Q000188:drug therapy*; D010123:Oxyuriasis / Q000188:drug therapy; D013322:Strongyloidiasis / Q000188:drug therapy; D014257:Trichuriasis / Q000188:drug therapy
D000871:Anthelmintics; D001562:Benzimidazoles; D015766:Albendazole
L'albendazole. Evaluation de la tolérance et de l'efficacité dans l'oxyurose, la trichocéphalose, l'ankylostomose, l'ascaridiose, l'anguillulose.