[Results of treatment of adult acute leukemias: critical analysis in an unselected group of patients].
58 adult patients with acute leukemia were analyzed in respect to the rate of first remission induction, remission duration, survival, and treatment of relapse. A selection of subgroups has been avoided to reflect clinical reality. Although our results of remission induction were slightly under those reported from other groups, the duration of remission and survival was favorably comparable. The prognostic value of LDH and systemic infection on admission for the outcome of the disease has been evaluated. Selective decontamination of the G.I.-tract reduced the rate of life-threatening infections and increased the rate of complete remissions significantly. LDH was of no importance in predicting the likelihood of achieving complete remission or duration of complete remission.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003106:Colon / Q000382:microbiology; D003666:Decontamination; D005334:Fever / Q000209:etiology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007938:Leukemia / Q000188:drug therapy*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy; D011379:Prognosis
D000970:Antineoplastic Agents; D007770:L-Lactate Dehydrogenase
Behandlungsergebnisse akuter Leukämien im Erwachsenenalter: Kritische Analyse eines unselektionierten Krankengutes.