[Superficial herpes simplex keratitis. Double-blind comparative trial of acyclovir and idoxuridine (author's transl)].
In a double-blind, randomized trial 52 patients with superficial herpes simplex keratitis were treated with a new antiviral compound, acylclovir (ACV) 3% ointment, or with idoxuridine (IDU) 0.5% ointment. No statistically significant difference was found in the number of patients cured with either drug, but healing was achieved more rapidly with ACV than with IDU.
D000212:Acyclovir; D000328:Adult; D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006147:Guanine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007065:Idoxuridine / Q000008:administration & dosage* / Q000009:adverse effects; D007635:Keratitis, Dendritic / Q000188:drug therapy*; D008297:Male; D009824:Ointments; D011817:Rabbits; D013997:Time Factors
D000998:Antiviral Agents; D009824:Ointments; D006147:Guanine; D007065:Idoxuridine; D000212:Acyclovir
Kératite herpétique superficielle. Traitement comparatif en double insu par acycloriv et idoxuridine.