The effect of insulin-induced hypoglycemia with and without atropine on plasma GIP in man.
Insulin-induced hypoglycemia caused a modest but significant (p = 0.031) increase in plasma GIP. This increase was significantly (p = 0.031) attenuated when atropine was given together with insulin, indicating that the vagal nerves play a major role in the release of plasma GIP during hypoglycemia.
D000328:Adult; D001285:Atropine / Q000494:pharmacology*; D001786:Blood Glucose / Q000378:metabolism*; D005215:Fasting; D005744:Gastric Acid / Q000378:metabolism; D005749:Gastric Inhibitory Polypeptide / Q000097:blood*; D005768:Gastrointestinal Hormones / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000494:pharmacology*; D008297:Male; D011187:Posture; D013997:Time Factors
D001786:Blood Glucose; D005768:Gastrointestinal Hormones; D007328:Insulin; D005749:Gastric Inhibitory Polypeptide; D001285:Atropine