A method for stereotaxic implantation in neonatal rats.
Presented are methods of implanting chronically indwelling electrodes or cannulas into brain infant rats. Anesthesized pups are restrained in a flexible alginate mold that is place in the stereotaxic instrument. Details of electrode implant are given. We routinely use these methods to accurately place electrodes into subcortical structures of 3- to 15-day-old pups with less than 2% loss of the implant.
D000818:Animals; D000831:Animals, Newborn; D001931:Brain Mapping; D002408:Catheters, Indwelling; D004567:Electrodes, Implanted; D051381:Rats; D013238:Stereotaxic Techniques