Detection of ligand-induced and syncatalytic conformational changes of enzymes by differential chemical modification.
D000345:Affinity Labels; D001051:Apoenzymes / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D001665:Binding Sites; D002250:Carbon Radioisotopes; D002384:Catalysis; D055598:Chemical Phenomena; D002621:Chemistry; D003432:Cross-Linking Reagents / Q000494:pharmacology; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004798:Enzymes / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D007553:Isotope Labeling; D007700:Kinetics; D010447:Peptide Hydrolases; D010782:Photolysis; D011485:Protein Binding; D011487:Protein Conformation / Q000187:drug effects; D011730:Pyridoxal; D011733:Pyridoxamine; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D014316:Tritium
D000345:Affinity Labels; D001051:Apoenzymes; D002250:Carbon Radioisotopes; D003432:Cross-Linking Reagents; D004791:Enzyme Inhibitors; D004798:Enzymes; D007202:Indicators and Reagents; D013439:Sulfhydryl Reagents; D014316:Tritium; D011730:Pyridoxal; D011733:Pyridoxamine; D001219:Aspartate Aminotransferases; D010447:Peptide Hydrolases