Insulin degradation in human erythrocyte. Effects of reduced glutathione on insulin degradation by hemolysate.
In this study the Authors have evaluated the effects of reduced glutathione on insulin-degrading activity of hemolysate. The GSH increases, in a manner proportional to its concentration, the insulin degradation and this effect is due to the increase the Vmax of the same enzymatic system responsible of insulin degradation observed in absence of exogenous glutathione.
D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005978:Glutathione / Q000494:pharmacology*; D006461:Hemolysis; D006801:Humans; D007328:Insulin / Q000097:blood*
D007328:Insulin; D005978:Glutathione