title: [The radioimmunological assaying of the luteinizing hormone-releasing hormone (LH-RH) in human beings. A general review (author's transl)].
abstract: The authors attempted to work out a synthesis of the known factors about the specifications required for the levels of LH-RH and for finding this hormone in different human biological milieux. Searching for endogenous LH-RH in women, men and children has given very different results. The disparity between the levels that have been found, which are often at the very limits of detection by the methods used, can be explained by the type of specification of the level and by the effects of the biological milieu used and by the breakdown of endogenous LH-RH in the living organism. The conclusion is that the values that have been found up to now are not really reliable and of no great use in human clinical work.
mesh_terms: D000918:Antibody Specificity; D003429:Cross Reactions; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000032:analysis* / Q000097:blood / Q000276:immunology; D006801:Humans; D008593:Menopause; D008598:Menstruation; D011863:Radioimmunoassay / Q000379:methods; D012737:Sex Factors
chemical_list: D007987:Gonadotropin-Releasing Hormone
vernacular_title: Dosage radioimmunologique de la gonadolibérine (LH-RH) chez l'être humain. Revue générale.