T and B lymphocytes in the aqueous humor of patients with uveitis.
Sixteen patients with different types of uveitis (ocular toxoplasmosis, chronic cyclitis, Vogt-Koyanagi-Harada syndrome, Behçet's syndrome, ocular herpes, and a probable nematode) had the aqueous humor withdrawn and had the number of T, B, and null lymphocytes assessed. T and B lymphocytes were identified by rosette formation with sheep erythrocytes and with human erythrocytes sensitized with IgM antibody and complement or zymosan-C3 complexes, respectively. A much higher number of T lymphocytes than B lymphocytes was observed in all cases. The results were not influenced by treatment with steroids or immunosuppressive drugs for local, periocular, or systemic effects.
D001082:Aqueous Humor / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D001528:Behcet Syndrome / Q000276:immunology; D005128:Eye Diseases / Q000276:immunology; D006801:Humans; D007158:Immunologic Techniques; D007635:Keratitis, Dendritic / Q000276:immunology; D009349:Nematode Infections / Q000276:immunology; D012397:Rosette Formation; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology*; D014605:Uveitis / Q000276:immunology*