Bactericidal activity in fractionated granule contents from human polymorphonuclear leukocytes: studies with leukocytes from normal individuals.
Sephadex G-100 chromatographic fractions of granule extracts from normal human polymorphonuclear leukocytes, exhibiting differences from fractions previously obtained from leukemic polymorphonuclear leukocytes, possessed cationic proteins with distinct bactericidal activity against cell wall mutants of Salmonella typhimurium LT2.
D001770:Blood Bactericidal Activity; D001798:Blood Proteins / Q000494:pharmacology*; D002850:Chromatography, Gel; D003594:Cytoplasmic Granules / Q000032:analysis; D006801:Humans; D007938:Leukemia / Q000097:blood; D009154:Mutation; D009504:Neutrophils / Q000032:analysis* / Q000648:ultrastructure; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics
D001798:Blood Proteins