title: Validation of cardiac output estimates by digital video subtraction angiography in dogs. Correlation with thermodilution values.
abstract: To determine the validity of cardiac output estimates obtained by digital video subtraction angiography (DVSA), they were compared with thermodilution values in 6 anesthetized dogs. Multiple levels of cardiac output were produced in each dog by graded openings of peripheral arteriovenous fistulas. Both direct contrast and mask-mode images were evaluated. There was good correlation between thermodilution and direct contrast values (r = 0.88) as well as between thermodilution and mask-mode values (r = 0.89), though the mask-mode outputs were 12 +/- 1.1% less than the direct contrast values (p less than 0.05). Direct contrast and mask-mode values correlated well (n = 6; r greater than or equal to 0.95). Digital outputs exhibited little variation, indicating excellent reproducibility. These results demonstrate the validity of area-length estimates of cardiac output by DVSA.
mesh_terms: D000790:Angiocardiography / Q000379:methods*; D000818:Animals; D001164:Arteriovenous Fistula / Q000503:physiopathology; D002302:Cardiac Output; D004285:Dogs; D006339:Heart Rate; D009200:Myocardial Contraction; D013318:Stroke Volume; D013382:Subtraction Technique; D013815:Thermodilution