title: [Sodium phosphocreatine and the cardiovascular and respiratory systems].
abstract: In the dog, rat and chick, phosphocreatine-Na has not caused, from an experimental point of view, significative modifications of the cardiovascular- and respiratory-apparatus, of the reactivity of the cardio-regulator centers, of the baroreceptorial carotid-sinus and glomus reactivity, of the gangliar-, muscarinic-, histaminergic-, dopaminergic-, beta-adrenergic- and serotoninergic- vasomotor reactivity; only the vasomotor reactivity of a constrictive-type induced by epinephrine, nor-epinephrine, occlusion of the two common carotid arteries, hypertension and by BaCl2 is moderately reduced. It is interesting to note that the hypotensive response evoked by adenosine was augmented.
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002319:Cardiovascular System / Q000187:drug effects*; D002645:Chickens; D004285:Dogs; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D010725:Phosphocreatine / Q000494:pharmacology*; D011652:Pulmonary Circulation / Q000187:drug effects; D051381:Rats; D012137:Respiratory System / Q000187:drug effects*
chemical_list: D010725:Phosphocreatine
vernacular_title: Fosfocreatina sodica ed apparato cardiovascolare e respiratorio.