[The kidney in shock. A new experimental method for the induction of controlled shock. I].
In this research we identify a new experimental model to study the shock-kidney, since this complication occurs with discreet frequency during high surgery operation. The model that better reproduce the surgical shock-kidney is the controlled hypovolemic shock. We used for this experiment five pigs of weight between 40 and 50 kg and were studied the following data: Ecg, arterial pressure, central venous pressure, diuresis (by incannulation of both ureters), renal arterial flow, levels of the renin in the renal vein. The measurements were made before, during and after the shock. The hypovolemic shock was induced by removing from carotid artery a sufficient quantity of blood to bring the pressure to 45-50 mmHg. This pressure level was kept constant for 120 min and then was reported to normal level by introducing the blood previously removed. During the experiment no kind of drugs were used.
D000818:Animals; D001794:Blood Pressure; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology*; D012039:Regional Blood Flow; D012083:Renin / Q000097:blood; D012769:Shock / Q000503:physiopathology*; D013552:Swine
D012083:Renin
Il rene da shock. Nuova tecnica sperimentale per l'induzione dello shock controllato. Nota I.