title: Treatment of stress response to laryngoscopy and intubation with fentanyl.
abstract: The cardiovascular response to laryngoscopy and intubation was investigated in lightly anaesthetised patients admitted to hospital for elective intracranial surgery. One group of patients was given fentanyl 5 microgram/kg body weight before induction with thiopentone and suxamethonium. The other group served as controls. Fentanyl treatment caused a significant attenuation of the blood pressure and pulse response to laryngoscopy and intubation. Different techniques for induction of anaesthesia are discussed in relation to the demands of neuroanaesthesia.
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D001921:Brain / Q000601:surgery; D002986:Clinical Trials as Topic; D005260:Female; D005283:Fentanyl / Q000627:therapeutic use*; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007828:Laryngoscopy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011292:Premedication; D011897:Random Allocation
chemical_list: D005283:Fentanyl