[Clinical trial of isaxonine in alcoholic polyneuritis (author's transl)].
Forty six confirmed cases of polyneuritis were treated in a double-blind survey for 4 to 5 months. The results were evaluated in terms of clinical examinations and electrophysiological tests. There was a clearly significant difference in favour of isaxonin. Tolerance was good, in particular insofar as the liver was concerned. The dosage of 1175 to 1500 mg/day for adults seemed adequate.
D000437:Alcoholism / Q000150:complications*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004594:Electrophysiology; D006801:Humans; D011115:Polyneuropathies / Q000188:drug therapy* / Q000209:etiology; D011743:Pyrimidines / Q000009:adverse effects / Q000627:therapeutic use*
D011743:Pyrimidines; C020375:isaxonine
Essai de l'isaxonine dans les polynévrites éthyliques.