[Islet cell antibodies in diabetic patients with other autoimmune diseases (author's transl)].
The presence of antibodies directed against pancreatic islet cells was investigated in 18 insulin pendent diabetic patients with autoimmune disease (Group 1), in 8 insulin-independent diabetic patients with autoimmune disease (Group 2), in 42 non-diabetic patients with thyroid antibodies (Group 3), in 18 patients with antibodies against gastric parietal cells (Group 4) and in 100 healthy subjects (controls). Islet cell antibodies were found in 46% of group 1 patients and in only 1 patient of group 3 and 1 control. This would suggest the existence of a special form of autoimmune insulin-dependent diabetes characterized by a high incidence of islet cell antibodies and associated with other autoimmune diseases.
D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000150:complications*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000276:immunology; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007515:Islets of Langerhans / Q000276:immunology*; D008297:Male; D013961:Thyroid Gland / Q000276:immunology
D001323:Autoantibodies; D007328:Insulin
Anticorps anti-cellules des îlots pancréatiques chez des malades atteints d'autres maladies auto-immunes.