title: Povidone-iodine irrigation of the subcutaneous tissue to prevent surgical wound infections.
abstract: In a prospective randomized trial, the influence of irrigation of the subcutaneous tissue using povidone-iodine solution upon the development of postoperative wound infection was examined in 592 patients undergoing general surgical operative procedures. No beneficial effect of irrigation with povidone-iodine solution could be demonstrated, nor could it be demonstrated in the group as a whole or in the subgroups according to bacterial contamination.
mesh_terms: D000005:Abdomen / Q000601:surgery; D002986:Clinical Trials as Topic; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D011182:Postoperative Care; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000517:prevention & control*; D007507:Therapeutic Irrigation
chemical_list: D011206:Povidone-Iodine; D011205:Povidone