title: [Early diagnosis of thyroid cancer in endemic goitre area reflections and management based on the epidemiological situation in Tyrol (author's transl)].
abstract: Until recently the prognosis of thyroid cancer has been poor in this endemic goitre area due to the predominance of aggressive tumour types and belated diagnosis of the carcinoma. Iodine prophylaxis has changed this epidemiological profile: the mortality of goitre has generally decreased and there has been a relative increase in differentiated carcinomas. Preoperative diagnosis and operability have been favourably influenced by this new situation. Thus, whereas from 1960 to 1967 radical operation was impossible in 78.6% of thyroid cancers, between 1978 and 1981 only 12.4% of all cases had invasive tumours of distant metastases at the time of operation and 79.3% of all patients were staged as To-2N0Mo. An improvement in survival rate can be expected with early diagnosis of thyroid cancer. Nevertheless, individual prognostic statements can be made only after evaluation of these findings according to "prognostic systems", for in thyroid cancer--as in no other kind of carcinoma--prognosis is determined by a combination of the patient's age and sex, cell type and histological tumour pattern and TNM status.
mesh_terms: D000236:Adenoma / Q000473:pathology; D001317:Austria; D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology; D006043:Goiter, Endemic / Q000175:diagnosis*; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D011877:Radionuclide Imaging; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013997:Time Factors
vernacular_title: Die Früherfassung des Schilddrüsenkarzinoms im Strumaendemiegebeit. Uberlegungen und Vorgehen auf der Basis der epidemiologischen Verhältnisse in Tirol.