title: Human corticosteroid binding globulin.
abstract: The literature on corticosteroid binding globulin (transcortin) in the human is reviewed under the following headings: physicochemical properties, biosynthesis, measurement, and physiological, pharmacological and pathological variations with particular emphasis of the effects of pregnancy and oral contraceptives. Finally, the physiological implications of corticosteroid binding globulin are discussed.
mesh_terms: D000303:Adrenal Cortex Diseases / Q000378:metabolism; D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000367:Age Factors; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002940:Circadian Rhythm; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D008797:Metyrapone / Q000494:pharmacology; D009401:Nephrosis / Q000378:metabolism; D011247:Pregnancy; D011372:Progestins / Q000494:pharmacology; D012737:Sex Factors; D013739:Testosterone / Q000494:pharmacology; D013959:Thyroid Diseases / Q000378:metabolism; D014156:Transcortin / Q000096:biosynthesis / Q000378:metabolism / Q000494:pharmacology
chemical_list: D000305:Adrenal Cortex Hormones; D004967:Estrogens; D011372:Progestins; D013739:Testosterone; D014156:Transcortin; D006854:Hydrocortisone; D008797:Metyrapone