Interaction between human neutrophils and group B streptococci (GBS) and group antigens, monitored by Luminol-dependent chemiluminescence.
Interaction between the five serotypes of GBS and human neutrophils was investigated using Luminol-dependent chemiluminescence. A considerable variation in response, and a variable dependence pre-opsonisation was demonstrated both for while bacteria and HCl-extracts. These preliminary results may have relevance to clinical infection with GBS and demonstrate hitherto unrecognised differences in the nature of "group-specific" antigen extracts from GBS serotypes.
D000942:Antigens, Bacterial / Q000276:immunology*; D006801:Humans; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology; D009504:Neutrophils / Q000276:immunology / Q000378:metabolism*; D009895:Opsonin Proteins / Q000276:immunology; D013292:Streptococcus agalactiae / Q000145:classification / Q000276:immunology*
D000942:Antigens, Bacterial; D009895:Opsonin Proteins; D008165:Luminol