The early arterial effects of renovascular hypertension in rats.
Experimental hypertension in rats increases vascular permeability to tracers such as Trypan blue or colloidal iron. The amount of tracer which enters the tissues examined : brain, skin and aortic wall is proportional to the damage of the vascular wall. The highest permeability increase was seen in the aortic wall, then in the skin. Brain vessels seem to be the most resistant to permeability increase induced by experimental hypertension.
D000818:Animals; D001158:Arteries / Q000166:cytology / Q000503:physiopathology*; D001794:Blood Pressure; D001834:Body Water / Q000378:metabolism; D002199:Capillary Permeability; D004247:DNA / Q000096:biosynthesis; D006977:Hypertension, Renal / Q000503:physiopathology*; D006978:Hypertension, Renovascular / Q000473:pathology / Q000503:physiopathology*; D007501:Iron; D008297:Male; D011392:Proline / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014343:Trypan Blue
D004247:DNA; D011392:Proline; D007501:Iron; D014343:Trypan Blue