Inhibition of leukocyte adherence by a 3 M potassium chloride extracts of human malignant melanoma.
The tube leukocyte adherence inhibition (LAI) assay was performed using 3 M KCl extracts of malignant melanoma materials and leukocytes taken from 24 malignant melanoma patients. Of these patients, 21 participated in sequential studies which employed a minimum of 3 time points. An increasing non-adherence index (NAI) was found in 5 of 6 patients who exhibited a favorable disease course. In 5 of 6 patients with an unfavorable disease course, NAI values decreased. In 8 of 9 patients with stable disease, the NAI also was stable. These results indicate that the trend of sequential LAI studies reflects the clinical course of malignant melanoma patients.
D005260:Female; D006801:Humans; D007158:Immunologic Techniques; D007957:Leukocyte Adherence Inhibition Test; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D008545:Melanoma / Q000276:immunology* / Q000473:pathology; D008875:Middle Aged; D011189:Potassium Chloride
D011189:Potassium Chloride