[Metabolic and hematologic changes in the northern red-backed vole Clethrionomys rutilus and the large-toothed red-backed vole Clethrionomys rufocanus during short-term starvation and refeeding].
The effect of starvation has been investigated on the content of glucose and lipids in the blood plasma, on the level of leucocytes in the peripheral blood and on the concentration of total lipids and glycogen in the liver. It was found that in both species of the voles, starvation within 20-22 hours sharply decreases glucose content and increases lipid content of the blood plasma. The liver glycogen becomes almost completely exhausted. These changes are more significant than those observed under similar conditions in laboratory rodents (albino mice and rats). During starvation of the voles, the level of leucocytes drastically decreases, whereas lipid content of the liver significantly increased. These changes are absent in laboratory rodents. The decrease in the content of glucose and in the level of leucocytes in the blood is more significant in C. rufocanus than in C, rutilis. On the contrary, accumulation of the lipids in the liver is more intense in the latter. The recovery of the investigated indices after refeeding is very slow. Possible significance of these re-arrangements for temperature and immune homeostases, as well as for regulation of other functions in the organism, is discussed.
D000818:Animals; D003411:Arvicolinae / Q000378:metabolism*; D001786:Blood Glucose / Q000378:metabolism; D005247:Feeding Behavior / Q000502:physiology*; D007958:Leukocyte Count; D050356:Lipid Metabolism; D008112:Liver Glycogen; D013217:Starvation / Q000378:metabolism*; D013997:Time Factors
D001786:Blood Glucose; D008112:Liver Glycogen
Metabolicheskie i gematologicheskie sdvigi u krasnoĭ Clethrionomys rutilus i krasno-seroĭ Clethrionomys rufocanus polevok pri neprodolzhitel'nom golodanii i vozobnovlenii pitaniia.