Correcting the phenotype of the epidermis from chick embryos homozygous for the gene scaleless (sc/sc).
Scutate scales are completely missing in the scaleless (sc/sc) mutant chicken. Organ cultures consisting of epidermis from sc/sc embryos combined with normal (+/+) scale dermis of the same developmental age produce the scaleless phenotype, but the same scaleless epidermis in combination with normal dermis from more differentiated embryonic scales forms perfectly normal scales.
D000818:Animals; D002642:Chick Embryo; D005241:Feathers / Q000502:physiology; D006720:Homozygote; D010641:Phenotype; D012867:Skin / Q000196:embryology; D016038:Skin Transplantation