Distribution of blood antigen H in human buccal epithelium of secretors and non-secretors.
The distribution of blood group antigen H in human buccal epithelium was examined in 22 individuals, 16 secretors and six non-secretors of blood group antigens in the saliva. An extract of Ulex europeus was used as marker of blood group antigen H in a triple layer immunofluorescence technique. The cell membranes of the spinous cell layer stained positively in all individuals, whereas the basal cells reacted negatively. Secretors and non-secretors had similar distributions of blood group antigen H in the buccal epithelium. However, a significantly higher amount of blood group antigen H was found in secretors than in non-secretors. The study indicates that an extract of Ulex europeus is a valuable marker for blood group antigen H in studying the distribution of this antigen in oral epithelium.
D000017:ABO Blood-Group System / Q000276:immunology*; D002462:Cell Membrane / Q000276:immunology; D002610:Cheek; D004848:Epithelium / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000276:immunology*; D014018:Tissue Distribution
D000017:ABO Blood-Group System