[The artificial pancreas in the evaluation of insulin sensitivity in healthy subjects].
24-hours peripheral insulin sensitivity was studied in 5 healthy subjects by mean of artificial pancreas (Biostator), using the glycemic clamp technique (100 mg%). A sharp rise of insulin sensitivity (expressed as glucose required/insulin evoked ratio) was obtained in the morning, confirming our previous data observed by insulin tolerance test, but in a more physiological condition. The subjects appeared well synchronized as documented by statistically significant circadian rhythms in both serum cortisol and body temperature.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001831:Body Temperature; D002940:Circadian Rhythm; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007332:Insulin Infusion Systems; D007333:Insulin Resistance; D008297:Male
D001786:Blood Glucose; D007328:Insulin; D006854:Hydrocortisone
Il pancreas artificiale nella valutazione della sensibilita all'insulin nel soggetto sano.