Behavioral versus pharmacological treatments for essential hypertension--a needed comparison.
Comparison of mild-to-moderate essential hypertension patients treated for 6 weeks by antihypertensive medication versus metronome-conditioned relaxation versus biofeedback versus a mild exercise control procedure showed that those on medication achieved the greatest decrease in blood pressure. The relaxation and biofeedback groups decreased more than the mild exercise group, as predicted, but not significantly more. The differences in benefits of the groups were not a function of group differences in initial blood pressure levels nor in compliance. Nor did the groups differ in the side effects that are usually associated with medications. A second phase of 6 weeks with another treatment or combination of treatments did not add significantly. Some characteristics of patients moderately predicted treatment benefits, for example, high scores on the Jenkins Activity Survey Scales (1) [Type A, S or H], for the relaxation and biofeedback treated patients predicted which patients received greater benefits.
D000328:Adult; D001521:Behavior Therapy / Q000379:methods*; D001676:Biofeedback, Psychology; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006973:Hypertension / Q000523:psychology / Q000628:therapy*; D008750:Methyldopa / Q000627:therapeutic use*; D008875:Middle Aged; D005082:Physical Exertion; D011433:Propranolol / Q000627:therapeutic use*; D012064:Relaxation Therapy; D013315:Stress, Psychological / Q000523:psychology
D006852:Hydrochlorothiazide; D008750:Methyldopa; D011433:Propranolol