Human alveolar macrophages express Ia-like antigens.
Monoclonal antibody to la-like antigens was used to demonstrate the presence of these antigens on human alveolar macrophages. Immunoprecipitation demonstrated the 27,000 and 34,000 molecular weight peaks that correspond to the la-like antigen subunits. Immunofluorescence confirmed the presence of la-like antigens on alveolar macrophages but not on other bronchoalveolar cells. The presence of alveolar macrophage la-like antigens may be important in cellular interactions.
D000911:Antibodies, Monoclonal; D002450:Cell Communication; D011232:Chemical Precipitation; D005455:Fluorescent Antibody Technique; D000949:Histocompatibility Antigens Class II; D006801:Humans; D008264:Macrophages / Q000276:immunology*; D011650:Pulmonary Alveoli / Q000166:cytology*
D000911:Antibodies, Monoclonal; D000949:Histocompatibility Antigens Class II