title: [The pathophysiology and immune response to broncho-pulmonary bacterial infections (author's transl)].
abstract: This study is in two parts. The first is devoted to a brief reminder of those situations in which pathogenic microbes invade the respiratory tract and is concerned with: the rapid elimination of the pathogen, thanks to the intervention of the first line of defence of the lung; a delayed elimination which sets in action complementary mechanisms inducing an inflammatory response; the overflow of the defence system with the development of the infectious illness. The second part is devoted to a review of the causes of failure of the defence mechanisms against the microbes. Two series of events are discussed: first constitutional immune deficiency and secondly acquired deficiencies.
mesh_terms: D000917:Antibody Formation; D001424:Bacterial Infections / Q000276:immunology; D002633:Chemotaxis; D003165:Complement System Proteins; D006801:Humans; D007154:Immune System Diseases / Q000150:complications; D007111:Immunity, Cellular; D007249:Inflammation / Q000276:immunology; D008264:Macrophages / Q000502:physiology; D010587:Phagocytosis; D011014:Pneumonia / Q000276:immunology; D012141:Respiratory Tract Infections / Q000150:complications / Q000276:immunology*
chemical_list: D003165:Complement System Proteins
vernacular_title: Bases histophysiologiques et immunitaires de l'infection broncho-pulmonaire bactérienne.