Restoration of the impaired lymphocyte stimulation in old people by thymopoietin pentapeptide.
The number of E-rosette forming cells was normal in old people with minor pathology, but the lymphocyte stimulation by concanavalin A was decreased. A single administration of thymopoietin pentapeptide 10 mg I.M. enhanced the impaired lymphocyte stimulation.
D000368:Aged; D000375:Aging; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D010446:Peptide Fragments / Q000494:pharmacology*; D012397:Rosette Formation; D016305:Thymopentin; D013946:Thymopoietins / Q000494:pharmacology*; D013951:Thymus Hormones / Q000494:pharmacology*
D010446:Peptide Fragments; D013946:Thymopoietins; D013951:Thymus Hormones; D003208:Concanavalin A; D016305:Thymopentin