Urinary virulence of Proteus mirabilis in two experimental mouse models.
Two experimental mouse models were tested for their suitability in measuring urinary virulence of Proteus mirabilis. In the first model, the kidney-infecting dose and lethal dose were measured. In the second model, the kinetics of the numbers of bacteria in the kidneys and other organs of the mouse were monitored for 13 h after injection.
D000818:Animals; D004195:Disease Models, Animal; D007668:Kidney / Q000382:microbiology; D008099:Liver / Q000382:microbiology; D051379:Mice; D011512:Proteus Infections / Q000382:microbiology*; D011513:Proteus mirabilis / Q000472:pathogenicity*; D013154:Spleen / Q000382:microbiology