Absorption of anti-Chido from serum using autologous red blood cells coated with homologous C4.
A method is described which absorbs anti-Chido from serum without reducing the strength of other alloantibodies. Autologous red blood cells are coated with homologous C4 by a low-ionic-strength method and then used for the absorption. This is a practical method for removing anti-Chido from serum so that underlying alloantibodies may be identified and compatibility testing performed.
D000042:Absorption; D001789:Blood Group Antigens / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D003181:Complement C4 / Q000378:metabolism*; D006801:Humans; D007158:Immunologic Techniques; D007518:Isoantibodies / Q000276:immunology
D001789:Blood Group Antigens; D003181:Complement C4; D007518:Isoantibodies