Alterations of acidic and neutral glycopeptides during the post-natal growth period of the mouse.
We have examined the electrophoretic pattern of mannose-labelled glycopeptides derived from liver, pancreas, heart, brain, lung and kidney. The various organs were removed from white Swiss mice of 4-5, 20 and 40 days of age as well as from adult animals. Our data demonstrated that each organ had a characteristic ratio of acidic to neutral glycopeptides and that this ratio, in some cases, was substantially modified as the animal grew, consistent with the hypothesis that these changes might play an important role in the development and physiological function of organs.
D000375:Aging; D000818:Animals; D001921:Brain / Q000254:growth & development; D006020:Glycopeptides / Q000096:biosynthesis*; D006321:Heart / Q000254:growth & development; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000254:growth & development; D008099:Liver / Q000254:growth & development; D008168:Lung / Q000254:growth & development; D008358:Mannose; D051379:Mice; D010179:Pancreas / Q000254:growth & development; D011865:Radioisotope Dilution Technique; D014316:Tritium
D006020:Glycopeptides; D014316:Tritium; D008358:Mannose