The mesothelium: its fibrinolytic properties.
We have investigated the fibrinolytic properties of the mesothelium by developing a test system in which standard tissue samples can be assessed in a comparative and semi-quantitative manner. The problem whether plasminogen activators were generated by the mesothelium itself or were transported from a subserosal site was also studied. A standard system was developed by using a uniform gelatin disc to obtain a monolayer imprint of mesothelium and subsequently incorporating several of these samples on a fibrin plate. Pure cultures of mesothelial cells were able to induce fibrinolysis.
D000818:Animals; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology* / Q000648:ultrastructure; D005342:Fibrinolysis; D005780:Gelatin; D006652:Histological Techniques; D006801:Humans; D010960:Plasminogen Activators / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D005780:Gelatin; D010960:Plasminogen Activators