Association between maternal Gm allotype and neonatal septicaemia with group B streptococci.
Thirty-four mothers to infants seriously infected with group B streptococci (GBS) were investigated for G1m (1) and G3m(5) allotype markers. The frequency of Gm (1, -5) was 14.7%, of Gm(1,5) 20.6% and Gm (-1, 5) 64.7%. There was a marked deficit Gm (1) individuals and the distribution significantly differed from that in the normal Swedish populations.
D005260:Female; D005787:Gene Frequency; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000096:biosynthesis / Q000235:genetics* / Q000276:immunology; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000235:genetics* / Q000276:immunology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D018805:Sepsis / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D013290:Streptococcal Infections / Q000453:epidemiology / Q000235:genetics / Q000276:immunology; D013292:Streptococcus agalactiae / Q000235:genetics / Q000276:immunology; D013548:Sweden
D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G