title: Chronic bullous dermatosis of childhood. Linear iga bullous dermatosis.
abstract: A 21/2-year-old boy had large, tense bullae on the groin, buttocks, legs and abdomen. A subepidermal vesicle was seen on histological study. Immunofluorescent studies revealed linear IgA at the basement membrane zone. There was no associated gastrointestinal abnormality or any other systemic feature. The patient responded dramatically to sulfapyridine. He has had no recurrence of the disease and negative immunofluorescence study results during two years of follow-up.
mesh_terms: D001485:Basement Membrane / Q000276:immunology; D002675:Child, Preschool; D002908:Chronic Disease; D003874:Dermatitis Herpetiformis / Q000276:immunology; D003937:Diagnosis, Differential; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D008297:Male; D010391:Pemphigoid, Bullous / Q000276:immunology*; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000276:immunology*; D013427:Sulfapyridine / Q000627:therapeutic use; D013450:Sulfones / Q000627:therapeutic use
chemical_list: D007070:Immunoglobulin A; D013450:Sulfones; D013427:Sulfapyridine