title: [Use of highly concentrated human fibrinogen in paediatric surgery - a new therapeutic principle (author's transl)].
abstract: When using fibrin glue we must distinguish, on the basis of the clinical results obtained, between an obsolute and a relative indication for glueing. Glueing of the oesophageal anastomosis in atresia effected by means of three of four fibres only definitely produces better results than suturing alone. Likewise, fixation of skin grafts and treatment of ruptured spleen are an exclusive indication for fibrin glueing. Endoscopic glueing of oesophagotracheal fistulas and treatment of rupture of the kidneys, liver and pancreas are essential indications for glueing, alone or together with suturing. Intestinal anastomoses which are in danger of becoming detached can be secured by means of fibrin, thus improving the results. This applies equally to all fields of plastic surgery. In bone surgery, small detached parts of cartilage or of bone can be fixed atraumatically by glueing. Finally, improved and accelerated reconstruction e.g. of removed bone cysts can be expected by inserting fibrin-spongiosa fillings.
mesh_terms: D001166:Arteriovenous Shunt, Surgical / Q000379:methods; D004933:Esophageal Atresia / Q000601:surgery; D004937:Esophageal Fistula / Q000601:surgery; D005340:Fibrinogen / Q000627:therapeutic use*; D006801:Humans; D016038:Skin Transplantation; D013161:Splenic Rupture / Q000601:surgery; D013518:Surgery, Plastic / Q000379:methods; D014014:Tissue Adhesives
chemical_list: D014014:Tissue Adhesives; D005340:Fibrinogen
vernacular_title: Anwendung von hochkonzentriertem Human-Fibrinogen in der kinderchirurgie - ein neues Therapieprinzip.