title: The treatment of severe Raynaud's phenomenon with verapamil.
abstract: Verapamil was evaluated in 16 patients with severe Raynaud's phenomenon. Fifty per cent of patients experienced subjective improvement by history, but only one patient had a substantial reduction in the frequency of Raynaud's phenomenon as assessed by diary analysis. We conclude that verapamil is not effective in most patients with severe Raynaud's phenomenon.
mesh_terms: D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006439:Hemodynamics; D006801:Humans; D011928:Raynaud Disease / Q000188:drug therapy* / Q000503:physiopathology; D014700:Verapamil / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D014700:Verapamil