Plasma insulin and C-peptide in normal and glucose intolerant males: the role of hepatic insulin uptake.
Plasma immunoreactive insulin and peptide were measured in the basal and glucose-stimulated state in middle-age males. Normals were compared with individuals with mild to moderate glucose intolerance. Ths results demonstrate the value of C-peptide measurements in the assessment of "true" insulin secretion and suggest that a reduced hepatic insulin extraction is a feature of the glucose intolerant state.
D002096:C-Peptide / Q000097:blood*; D003920:Diabetes Mellitus / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood* / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000097:blood*
D002096:C-Peptide; D007328:Insulin; D010455:Peptides