A study comparing indapamide with cyclopenthiazide in geriatric patients.
The efficacy of indapamide was compared with cyclopenthiazide in geriatric hypertensive patients. On admission to the study patients were randomly allocated following a placebo run-in period before therapy commenced. Indapamide produced a greater fall in blood pressure which was well maintained in contrast to cyclopenthiazide. Both drugs were well tolerated.
D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003518:Cyclopenthiazide / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007190:Indapamide / Q000627:therapeutic use*; D008297:Male; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D007190:Indapamide; D003518:Cyclopenthiazide