[Cutaneous mastocytosis in twins].
The case of a pair of fraternal twins of seven months of age with cutaneous Mastocyte disease is presented. A brief historical survey of this condition is made. The histological picture is described with special emphasis on the mastocyte and its physiopathology. A description of the clinical aspect of the Pigmentous Urticaria in children and a brief reference to the other clinical forms of Mastocyte disease in its localized and systemic manifestations are presented. The different etio-pathogenic genetic theories related to this disease are considered, on account of the occurrence of this condition in members of a same family and in identical and fraternal twins. A revision of cases available up to date is made. The conclusion is that the etio-pathogenic problem is not solved yet, although the Mastocyte disease is considered as depending on a hereditary factor, not clearly defined yet, predisposing to this condition.
D004200:Diseases in Twins; D005260:Female; D006801:Humans; D011247:Pregnancy; D012867:Skin / Q000473:pathology; D014429:Twins, Dizygotic; D014582:Urticaria Pigmentosa / Q000473:pathology
Mastocitosis cutánea en gemelos.