Allogenic bone transplantation. Part I. A review of the status of allogenic bone banks.
The various methods of preserving bone for implantation are reviewed. Biological assay systems to determine the physiological and osteogenic potential of the implant are discussed. Sterilization remains the major problem. The influence of high-energy irradiation of freeze-dried bone is still uncertain. Experimentally and clinically it was found that the immunological status of the freeze-dried allo-implant is biocompatible.
D000818:Animals; D001681:Biological Assay; D016025:Bone Transplantation; D005612:Freeze Drying; D005615:Freezing; D006801:Humans; D010215:Papio; D051381:Rats; D014015:Tissue Banks; D014021:Tissue Preservation; D014181:Transplantation Immunology; D014184:Transplantation, Homologous