title: Major developments in clinical chemical instrumentation.
abstract: The introduction of instrumentation into the clinical chemistry laboratory is reviewed for the period extending from about 1890 to 1960. Topics covered, from a historical point of view, include the microscope, analytical balance, and centrifuge, colorimetry and spectrophotometry, flame photometry, gasometric analysis, pH, electrophoresis, chromatography, radioisotopes, and automation.
mesh_terms: D002624:Chemistry, Clinical / Q000266:history* / Q000295:instrumentation*; D004586:Electrophoresis / Q000295:instrumentation; D049672:History, 19th Century; D049673:History, 20th Century; D006863:Hydrogen-Ion Concentration; D008853:Microscopy / Q000266:history; D010783:Photometry / Q000266:history; D013053:Spectrophotometry / Q000295:instrumentation; D014894:Weights and Measures / Q000266:history