Androgen transport proteins: physical properties, hormonal regulation, and possible mechanism of TeBG and ABP action.
The physical properties and hormonal regulation of testosterone estradiol binding globulin (TeBG) and androgen binding protein (ABP) are reviewed. Brief mention is made of prostatic binding protein. The discussion focuses on the mechanism of action for these proteins in androgen secretion, transport, and absorption and androgen binding models. Speculations are presented for the functional significance of these proteins.
D000367:Age Factors; D000727:Androgen-Binding Protein / Q000097:blood / Q000378:metabolism*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D005260:Female; D006801:Humans; D007526:Isoelectric Point; D008297:Male; D008593:Menopause; D008958:Models, Molecular; D008970:Molecular Weight; D011247:Pregnancy; D012671:Seminiferous Tubules / Q000254:growth & development; D012738:Sex Hormone-Binding Globulin / Q000097:blood / Q000378:metabolism*; D013045:Species Specificity; D013256:Steroids / Q000378:metabolism; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D000727:Androgen-Binding Protein; D002352:Carrier Proteins; D012738:Sex Hormone-Binding Globulin; D013256:Steroids