title: Glucagon and infusion cholangiography.
abstract: It has been previously suggested that glucagon improves the bile duct and gall-bladder opacification obtained by infusion cholangiography. One hundred and ninety consecutive patients referred for intravenous cholangiography were entered into a double-blind study designed to see if glucagon would in fact significantly improve bile duct opacification. All patients received a one hour intravenous infusion of iotroxamide at a rate of 3.15 mg/kg body weight/min. Glucagon did not enhance bile duct opacification, the mean post-injection scores for the two groups being 2.47 +/- 1.11 and 2.29 +/- 1.15 respectively. On the basis of the present study we cannot recommend the routine use of glucagon following infusion cholangiography.
mesh_terms: D001652:Bile Ducts / Q000187:drug effects*; D002758:Cholangiography / Q000379:methods*; D002986:Clinical Trials as Topic; D003287:Contrast Media / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D005704:Gallbladder / Q000187:drug effects; D005934:Glucagon / Q000494:pharmacology*; D006801:Humans; D007458:Iodipamide / Q000031:analogs & derivatives / Q000494:pharmacology; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; C012386:meglumine iotroxinate; D005934:Glucagon; D007458:Iodipamide