title: [Changes in intestinal transit time induced by bromopride in functional diseases of the colon].
abstract: Intestinal transit time was studied in two groups of 8 patients with irritable colon. In the first group, the time was longer than normal, whereas in the second it was accelerated. Three subjects in each group received a placebo, while the other five received 60 mg/day bromopride for 15 days. No change in transit time was noted in the controls. Two subjects in Group I displayed a significant reduction in transit time after bromopride, while deceleration and normalisation were observed in 4/5 patients in Group II.
mesh_terms: D000328:Adult; D002214:Capsules; D002986:Clinical Trials as Topic; D003109:Colonic Diseases, Functional / Q000188:drug therapy*; D004064:Digestive System / Q000187:drug effects* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D013997:Time Factors
chemical_list: D002214:Capsules; C013855:bromopride; D008787:Metoclopramide
vernacular_title: Modificazioni indotte dalla bromopride su tempo di transito intestinale nelle colopatie funzionali.