title: Silicone granuloma of the penis.
abstract: Injectable silicones have been applied to an undetermined number of men for penile augmentation. The practitioners of this art, whether lay or medical, have allegedly long discontinued treating penile size. In the literature to date, four men have been identified as having complications from this mode of therapy; three have had excisions of granulomatous masses secondary to the silicone; the third refused surgery. This paper reports an additional case of silicone granuloma of the penis, documented by biopsy, which necessitated two excisions to obtain a satisfactory size for copulation. Moreover, because of impotence, a Dow-Corning (Gerow design) penile prosthesis was inserted. The inflammatory response in this new case is identical to that found in other parts of the body, namely, multiple silicone droplets surrounded by multinucleated giant cells and chronic inflammatory cells.
mesh_terms: D000328:Adult; D005549:Foreign-Body Reaction / Q000150:complications; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D010409:Penile Diseases / Q000209:etiology* / Q000473:pathology; D010413:Penis / Q000601:surgery; D019736:Prostheses and Implants / Q000009:adverse effects*; D012828:Silicones
chemical_list: D012828:Silicones