The treatment of severe Raynaud's phenomenon with verapamil.
Verapamil was evaluated in 16 patients with severe Raynaud's phenomenon. Fifty per cent of patients experienced subjective improvement by history, but only one patient had a substantial reduction in the frequency of Raynaud's phenomenon as assessed by diary analysis. We conclude that verapamil is not effective in most patients with severe Raynaud's phenomenon.
D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D006439:Hemodynamics; D006801:Humans; D011928:Raynaud Disease / Q000188:drug therapy* / Q000503:physiopathology; D014700:Verapamil / Q000009:adverse effects / Q000627:therapeutic use*
D014700:Verapamil