A foreign body granuloma produced by an injectable collagen implant at a test site.
Zyderm collagen implant, a solubilized, purified, bovine collagen preparation for augmentation of soft tissue, produced a foreign body granuloma in a 37-year-old woman who had no history of immunologic disorders or autoimmune disease. The patient had received a small test implant to determine if she were sensitive to Zyderm. A very slight, borderline response occurred and a second test implant was administered. This second implant resulted in a foreign body granuloma that has persisted for ten months.
D000328:Adult; D003094:Collagen / Q000009:adverse effects; D005260:Female; D005542:Forearm / Q000473:pathology; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000473:pathology; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D019736:Prostheses and Implants / Q000009:adverse effects*
D003094:Collagen