title: Applications of 13C NMR to metabolic studies.
abstract: It is our view that the above examples, most of which have been published in the last two years, represent the beginnings of a new field and that in spite of major problems in instrumentation and programming, the essential feasibility of using enriched 13C substrates for metabolic processes as a noninvasive technique has been firmly established. With the caveat that a rigorous protocol for signal assignment must be devised, we can look forward to many applications of this method in a wide range of biological systems.
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D004926:Escherichia coli / Q000378:metabolism; D005943:Gluconeogenesis; D006019:Glycolysis; D008099:Liver / Q000378:metabolism; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D051379:Mice; D055585:Physical Phenomena; D010825:Physics; D011166:Porphyrins / Q000096:biosynthesis; D012441:Saccharomyces cerevisiae / Q000378:metabolism
chemical_list: D002247:Carbon Isotopes; D046911:Macromolecular Substances; D011166:Porphyrins