Experimental investigations into the clinical significance of bone growth at viscerocranial sutures.
The development of a viscerocranial suture under physiological conditions was investigated in a total of 37 pigs and the effects of various traumas on expected sutural bone growth were observed. Different operations were carried out on one side only in the vicinity of the zygomaticotemporal suture in 18-25 day old piglets. The animals were sacrificed six months after the operation. The skulls of some of the animals were macerated and subjected to macroscopic and radiological investigation. Both zygomatic arches were removed from each of the remaining animals and used for the production of undecalcified microtome and ground sections. Intravital fluorochrome labelling was used to determine the asymmetric growth at this suture; this is interpreted as being the formation of new bone following passive expansion of the sutural region. After injury or transplantation of the periosteum and after the healing of a narrow bone defect or fracture we observed either a continuous suture from the outset or the formation of a new fissure after osseous regeneration. Similar findings were also made after the transplantation of compact rib fragments into a sutural defect without subsequent bridging of the defect. Only after the transplantation of autologous pieces of cancellous rib into an osseous defect in the sutural region  was sutural ossification, accompanied by distinct deformation of the skull observed. As a clinical consequence of this it may be presumed that trauma or operation in the region of a suture has a considerable effect on the growth of the visceral cranium only if it results in premature synostosis.
D000818:Animals; D016025:Bone Transplantation; D003393:Cranial Sutures / Q000254:growth & development* / Q000601:surgery; D005260:Female; D008297:Male; D010012:Osteogenesis; D010027:Osteotomy; D010521:Periosteum / Q000637:transplantation; D012886:Skull / Q000254:growth & development*; D013552:Swine; D013701:Temporal Bone / Q000254:growth & development* / Q000601:surgery; D013997:Time Factors; D015050:Zygoma / Q000254:growth & development* / Q000601:surgery