Assessment of hypokinesia in Parkinsonism.
The measurement of movement time provides a satisfactory objective measure of hypokinesia in parkinsonism. It is relatively constant in normal subjects, and it is often greatly prolonged in parkinsonism and correlates with clinical disability. The reaction time is only of limited value, because of small difference from normal values and wide individual variations.
D000328:Adult; D000368:Aged; D001971:Bromocriptine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004873:Ergolines / Q000627:therapeutic use*; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008090:Lisuride / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009068:Movement; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology; D010919:Placebos; D011187:Posture; D013997:Time Factors
D004873:Ergolines; D010919:Placebos; D001971:Bromocriptine; D007980:Levodopa; D008090:Lisuride