title: Cancer and the kidney: complications of neoplasms.
abstract: Various renal complications occur during the course of neoplastic disease. The therapeutic and prognostic implications differ according to the reversibility of both the underlying malignancy and the superimposed complications in the kidney. Since the mechanisms of renal failure vary significantly in patients with different types of malignancy, it is essential to avoid generalizations about etiologic factors or likely outcomes of the disease processes. The pathophysiologic abnormalities should be determined in each patient, and the reversibility of both the neoplastic and problems assessed before therapeutic decisions are made. This often requires a team effort by the internist, oncologist, nephrologist, urologist and, most importantly, the patient.
mesh_terms: D000686:Amyloidosis / Q000150:complications; D000970:Antineoplastic Agents / Q000009:adverse effects; D004211:Disseminated Intravascular Coagulation / Q000150:complications; D006801:Humans; D006934:Hypercalcemia / Q000378:metabolism; D007167:Immunotherapy / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D007680:Kidney Neoplasms / Q000150:complications; D007684:Kidney Tubules / Q000378:metabolism; D007938:Leukemia / Q000150:complications; D008223:Lymphoma / Q000150:complications; D009101:Multiple Myeloma / Q000652:urine; D009369:Neoplasms / Q000150:complications*; D009404:Nephrotic Syndrome / Q000150:complications; D010266:Paraproteins / Q000652:urine; D011832:Radiation Injuries / Q000150:complications; D014517:Ureteral Obstruction / Q000150:complications; D014524:Urethral Obstruction / Q000150:complications; D014527:Uric Acid / Q000378:metabolism; D001748:Urinary Bladder Neck Obstruction / Q000150:complications; D014883:Water-Electrolyte Imbalance / Q000150:complications
chemical_list: D000970:Antineoplastic Agents; D010266:Paraproteins; D014527:Uric Acid