Asynchronous maturation of Plasmodium berghei exo-erythrocytic forms in rats.
Sporozoites of Plasmodium berghei berghei (NK-65 strain) were inoculated intravenously into four-week-old CFN rats. Liver biopsies were taken at intervals and the density of exo-erythrocytic forms per mm3 of liver were estimated. Results demonstrated asynchronous maturation and the gradual disappearance of exo-erythrocytic forms during the period 48 to 72 hours after infection.
D000818:Animals; D008099:Liver / Q000469:parasitology*; D008288:Malaria / Q000469:parasitology*; D010962:Plasmodium berghei / Q000254:growth & development*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors