Differentiation between the genera Mycobacterium, Rhodococcus and Nocardia by susceptibility to 5-fluorouracil.
A test for susceptibility to 5-fluorouracil was useful for differentiating between species of rapidly growing mycobacteria, and for differentiating the genus Rhodococcus from the genus Nocardia. The majority of rhodococci tested were susceptible to 5-fluorouracil (20 micrograms ml-1), whereas the majority of nocardiae tested were resistant to it. Strains of Nocardia asteroides sensu stricto could be divided into two subgroups by their reaction to 5-fluorouracil.
D005472:Fluorouracil / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000145:classification* / Q000187:drug effects; D009615:Nocardia / Q000145:classification* / Q000187:drug effects; D009616:Nocardia asteroides / Q000145:classification / Q000187:drug effects
D005472:Fluorouracil