HLA segregation of human T-cell subpopulation markers.
Antisera recognizing subsets of human T lymphocytes can be produced by planned immunizations involving HLA-A and HLA-B compatible donors. The reactivity of these antisera against some individuals of a population, but not others, show that they recognize a polymorphic cell surface component. The study of informative families shows the HLA linkage of at least some of these alloantigenic determinants.
D000918:Antibody Specificity; D002469:Cell Separation; D005190:Family; D005455:Fluorescent Antibody Technique; D005838:Genotype; D006680:HLA Antigens / Q000235:genetics*; D006238:Haploidy; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D007114:Immunization; D013601:T-Lymphocytes / Q000276:immunology*
D006680:HLA Antigens; D007106:Immune Sera