A comparison between aerosol and inhaled powder administration of fenoterol in adult asthmatics.
Eleven adult asthmatics were given fenoterol either as a metered aerosol dose or as an inhaled powder with appropriate controls, in a randomised double-blind fashion. The increase in FEV1 was the same after both dosage forms and no side effects occurred indicating that powder inhalation is a safe and effective alternative to aerosol inhalation in the treatment of asthma with sympathomimetics.
D000293:Adolescent; D000328:Adult; D000336:Aerosols; D000368:Aged; D001249:Asthma / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004983:Ethanolamines / Q000008:administration & dosage*; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage*; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D011208:Powders; D011897:Random Allocation
D000336:Aerosols; D003692:Delayed-Action Preparations; D004983:Ethanolamines; D011208:Powders; D005280:Fenoterol