[Immunomorphological and ultrastructural characteristics of hypophyseal adenomas in prolactinemia patients].
It was shown by means of electron microscopy and immunohistochemical study that in 11 of 15 patients with high preoperative prolactinemia the tumor consisted mainly of prolactin-containing cells. Small groups of them occurred in the tumors of 2 patients, whereas in 2 other cases prolactin was not detected in the tumor cells by immunohistochemical method. Electron microscopy demonstrated hypophyseal oncocytomas in these 2 cases. Appreciable differences in the blood prolactin concentration, depending on the tumor ultrastructure, were not observed.
D000238:Adenoma, Chromophobe / Q000276:immunology* / Q000378:metabolism / Q000648:ultrastructure; D000328:Adult; D005260:Female; D005455:Fluorescent Antibody Technique; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000276:immunology* / Q000378:metabolism / Q000648:ultrastructure; D011388:Prolactin / Q000097:blood* / Q000276:immunology / Q000378:metabolism
D011388:Prolactin
Immunomorfologicheskaia i ul'trastrukturnaia kharakteristika adenom gipofiza u bol'nykh s prolaktinemieĭ.