title: [Diagnosis, treatment and follow-up of a patient with pseudohypoaldosteronism (author's transl)].
abstract: We report about a girl, 22 months old, with pseudohypoaldosteronism. The clinical course was characterized mainly by renal salt loosing syndrome, complicated by suddenly occurring hyperkalemic phases and a complete inability of renal electrolyte and acid-base regulation. Congenital adrenal hyperplasia was excluded and the diagnosis based on renal salt wasting despite hyperaldosteronaemia and increased plasma renin activity. Diagnosis and therapy of pseudo-hypoaldosteronism are discussed as well as the problems of long-term oral sodium chloride substitution and long-term therapy with sodium-polystyrol-sulfonate, a cation-exchange resin.
mesh_terms: D000136:Acid-Base Equilibrium; D000450:Aldosterone / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006929:Hyperaldosteronism / Q000151:congenital* / Q000175:diagnosis / Q000378:metabolism; D007223:Infant; D011188:Potassium / Q000378:metabolism; D012083:Renin / Q000097:blood; D012964:Sodium / Q000378:metabolism; D012965:Sodium Chloride / Q000008:administration & dosage; D014882:Water-Electrolyte Balance
chemical_list: D012965:Sodium Chloride; D000450:Aldosterone; D012964:Sodium; D012083:Renin; D011188:Potassium
vernacular_title: Diagnose, Therapie und Verlaufsbeobachtung einer Patientin mit Pseudohypoaldosteronismus.