title: Protein transport across membranes: an introduction.
abstract: A characteristic feature of all cells is the transport of proteins across membranes. Biochemical studies with isolated subcellular components have revealed two types of proteins transport: co-translational, in which transport and synthesis are simultaneous, and post-translational, where transport occurs after the protein has been released form the ribosomes. Both types of transport involve interactions between particular regions of the protein and the membrane to be traversed. The details of this interaction are obscure. This review introduces the subject with emphasis on genetic studies with bacteria and biochemical studies with isolated chloroplasts.
mesh_terms: D000595:Amino Acid Sequence; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D002736:Chloroplasts / Q000378:metabolism; D004270:DNA, Circular; D004274:DNA, Recombinant; D004591:Electrophoresis, Polyacrylamide Gel; D008565:Membrane Proteins / Q000378:metabolism; D010047:Ovalbumin / Q000378:metabolism; D014176:Protein Biosynthesis; D011498:Protein Precursors; D011506:Proteins / Q000378:metabolism*; D012333:RNA, Messenger
chemical_list: D004270:DNA, Circular; D004274:DNA, Recombinant; D008565:Membrane Proteins; D011498:Protein Precursors; D011506:Proteins; D012333:RNA, Messenger; D010047:Ovalbumin