[Irregular anti-P1 allo-antibodies and sinensis clonorchiasis].
A parasitological and immuno-hematological study was undertaken simultaneously in fifty South-East asian refugees at the time of their arrival in France. --in this series the frequency of individuals having a P2 erythrocyte phenotype is 80%. --54 % of these immigrants were found to be carriers of Clonorchis sinensis, a parasite rarely found in Europe. --in 40,7 % of these subjects infested by Clonorchis sinensis, the following properties were disclosed concerning the P1 allo-antibody: slow-P1 red cell agglutination at 22 degrees C, no hemolysis of P1 red cells in vitro, IgM antibody, in weak titers. The immuno-hematological study of the immuno-serums with respect to distomian antigens coupled with adsorption-elution using P1+++ red cells shows a close immunological relationship between the antibody of parasite origin and the anti-P1 allo-antibody.
D000871:Anthelmintics / Q000627:therapeutic use; D000906:Antibodies / Q000276:immunology; D001789:Blood Group Antigens / Q000276:immunology*; D003003:Clonorchiasis / Q000097:blood* / Q000188:drug therapy; D003004:Clonorchis sinensis / Q000276:immunology; D006801:Humans; D007122:Immunoelectrophoresis; D007518:Isoantibodies / Q000276:immunology*; D008463:Mebendazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D010127:P Blood-Group System / Q000235:genetics / Q000276:immunology*; D010641:Phenotype
D000871:Anthelmintics; D000906:Antibodies; D001789:Blood Group Antigens; D007518:Isoantibodies; D010127:P Blood-Group System; D008463:Mebendazole; C018945:flubendazole
Allo-anticorps irréguliers anti-P1 et clonorchiase á Clonorchis sinensis.