Aetiology and management of non-specific vaginitis.
In a study of 100 women with non-specific vaginitis, characterised by a vaginal discharge which was malodorous and pruritic in most cases and caused dyspareunia and dysuria in some, Gardnerella vaginalis was isolated in 46% of patients. When present, G vaginalis was significantly associated with Mycoplasma hominis and Bacteroides species. Isolation of G vaginalis was unrelated to the presenting symptoms. Treatment with povidone-iodine pessaries for two weeks produced no pronounced benefit, either clinically or microbiologically, compared with a placebo. Nevertheless, 68% of all patients followed reported improvement four weeks after the start of treatment. The findings suggest that G vaginalis is one cause of non-specific vaginitis, which is more likely to be seen in women using oral contraceptives and is usually cured spontaneously.
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003276:Contraceptives, Oral / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D006192:Haemophilus Infections / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D011206:Povidone-Iodine / Q000627:therapeutic use; D014627:Vaginitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology
D003276:Contraceptives, Oral; D011206:Povidone-Iodine