Colicin A receptor: role of two Escherichia coli outer membrane proteins (OmpF protein and btuB gene product) and lipopolysaccharide.
ompF cells were completely resistant to colicin A, whereas btuB cells were partially resistant. The OmpF protein, in the presence of added lipopolysaccharide, inactivated colicin A. This inactivation was enhanced by added btuB gene product, btuB gene product with lipopolysaccharide did not inactivate colicin A. These data, together with the observation that vitamin B12 protected btuB+ cells from the killing effect of colicin A, suggest that the colicin A receptor in Escherichia coli K-12 is composed of the OmpF protein, the btuB gene product, and lipopolysaccharide.
D000327:Adsorption; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000032:analysis*; D003087:Colicins / Q000378:metabolism / Q000494:pharmacology; D004926:Escherichia coli / Q000032:analysis*; D029968:Escherichia coli Proteins; D008070:Lipopolysaccharides / Q000032:analysis*; D008565:Membrane Proteins / Q000032:analysis*; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic / Q000032:analysis*; D014805:Vitamin B 12 / Q000494:pharmacology
D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D003087:Colicins; D029968:Escherichia coli Proteins; D008070:Lipopolysaccharides; D008565:Membrane Proteins; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic; C028593:colicin receptor, E coli; D014805:Vitamin B 12