[Effect of different storage times of blood sera on their hormonal activity].
Hormonal activity of the sera was studied immediately after blood collection and 6 months, one year and 1.5 years following their storage at a temperature of -20 to 25 degrees C in 10 healthy males aged 18 to 20 years. It was found that differently directed changes in immunologic activity of blood serum hormones took place on long-term storage at low temperatures. The data obtained suggest that the adrenocorticotropic hormone, immunoreactive insulin, protein-bound iodine and follicle-stimulating hormone retain the immunologic activity not more than one year, while the hormone, stimulating interstitial cells, thyrotrophic hormone, somatotrophic hormone, 17-HOCS, testosterone and aldosterone up to 1-1.5 years. During this storage of frozen biosubstrates the recurrent freezing out that produces changes in the immunologic activity of some hormones should be excluded.
D000293:Adolescent; D000328:Adult; D001793:Blood Preservation; D001798:Blood Proteins / Q000378:metabolism; D005938:Glucocorticoids / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000097:blood*; D007455:Iodine / Q000097:blood; D008297:Male; D010908:Pituitary Hormones, Anterior / Q000097:blood*; D011485:Protein Binding; D012034:Refrigeration; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D001798:Blood Proteins; D005938:Glucocorticoids; D007328:Insulin; D010908:Pituitary Hormones, Anterior; D013739:Testosterone; D007455:Iodine
Vliianie razlichnykh srokov khraneniia syvorotok krovi na ikh gormonal'nuiu aktivnost'.