C. psittaci 6 BC soluble hemagglutinin: factors influencing the red cell receptor sites.
Human blood-group A, B and O erythrocytes did not possess receptor sites for either crude or ether-ethanol extracted chlamydial soluble hemagglutinin. Sensitive chicken erythrocytes were agglutinated to higher titres by ether-ethanol extracted than by crude chlamydial hemagglutinin. Studies indicated that trypsin-, chymotrypsin-, neuramanidase-sensitive receptor sites were not essential for binding of ether-ethanol extracted chlamydial hemagglutinin; neither were beta-glucuronidase- nor periodate-sensitive receptor sites essential. Since soluble chlamydial hemagglutinin consists of components of host cells and that of chlamydiae purification of hemagglutinin from chlamydiae is required in future studies.
D000017:ABO Blood-Group System; D000818:Animals; D002645:Chickens / Q000097:blood; D002691:Chlamydophila psittaci / Q000276:immunology*; D004912:Erythrocytes / Q000032:analysis*; D000431:Ethanol; D004986:Ether; D006384:Hemagglutination; D006388:Hemagglutinins; D006801:Humans; D009439:Neuraminidase / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000494:pharmacology; D011971:Receptors, Immunologic / Q000502:physiology*
D000017:ABO Blood-Group System; D006388:Hemagglutinins; D011971:Receptors, Immunologic; D004986:Ether; D000431:Ethanol; D009439:Neuraminidase; D010447:Peptide Hydrolases