Positive pressure ventilation and cranial volume in newborn infants.
The relationship between changes in airways pressure, pleural pressure, and cranial volume was studied in a group of sick newborn infants requiring ventilatory assistance. Cranial volume increased appreciably only when lung compliance was such that more than 20% of the applied airways pressure was transmitted to the pleural space, or if the absolute pleural pressure was greater than 4 cmH2O above atmospheric pressure. The findings stress the need for more-critical monitoring during periods of rapid change in lung compliance.
D001794:Blood Pressure; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000503:physiopathology / Q000628:therapy*; D007427:Intracranial Pressure; D008170:Lung Compliance; D010994:Pleura / Q000503:physiopathology; D011175:Positive-Pressure Respiration; D011312:Pressure; D012120:Respiration Disorders / Q000503:physiopathology / Q000628:therapy*; D012886:Skull / Q000473:pathology*