[Chronic, septic granulomatosis (author's transl)].
A case report is presented on an 18-month-old boy who suffered from recurrent infections from early infancy. He was hospitalised for osteomyelitis in the left elbow; differential diagnosis also raised the possibility of a Ewing sarcoma. We were, however, able to eliminate this possibility on the basis of clinical data. Together with the immunologist, we discovered a malfunction of the granulocytes, consisting essentially in the fact that certain bacteria, although phagocytised, cannot be killed off within the cells. This has therapeutic consequences, which are discussed in this paper together with questions of prognosis.
D003937:Diagnosis, Differential; D006105:Granulomatous Disease, Chronic / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008297:Male; D010019:Osteomyelitis / Q000209:etiology / Q000382:microbiology; D012512:Sarcoma, Ewing / Q000175:diagnosis; D012706:Serratia marcescens / Q000302:isolation & purification
Zur chronischen septischen Granulomatose.