title: Metabolism of mutagenic amino-gamma-carbolines in tryptophan pyrolysates.
mesh_terms: D000818:Animals; D001579:Benzopyrene Hydroxylase / Q000378:metabolism; D001711:Biotransformation; D002243:Carbolines / Q000378:metabolism*; D019388:Cytochrome P-450 CYP1A2; D003580:Cytochromes / Q000378:metabolism; D008401:Gas Chromatography-Mass Spectrometry; D007211:Indoles / Q000378:metabolism*; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000378:metabolism*; D009154:Mutation; D010634:Phenobarbital / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects; D013045:Species Specificity
chemical_list: D002243:Carbolines; D003580:Cytochromes; D007211:Indoles; D009153:Mutagens; D008748:Methylcholanthrene; C019133:3-amino-1-methyl-5H-pyrido(4,3-b)indole; D006899:Mixed Function Oxygenases; C027686:tryptophan pyrolysate N-hydroxylase; D001579:Benzopyrene Hydroxylase; C017170:Cyp1a2 protein, rat; D019388:Cytochrome P-450 CYP1A2; C019132:3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; D010634:Phenobarbital