title: [Serum pepsinogen: its value as index of basal and stimulated gastric acid secretion (author's transl)].
abstract: Group I pepsinogen serum levels (PG I) and gastric acid outputs were determined before ("basal") and after pentagastrin or insulin stimulation in 13 patients with active duodenal ulcer and in 4 patients with hyperselective vagotomy. There was a statistically significant correlation between basal PG I serum level and basal acid output (r = 0,88, p less than 0,01) and between PG I serum level 45 min after stimulation and peak acid output (r = 0,68, p less than 0,01). However, the scattering of individual values was such that serum PG I cannot be used as an index of gastric acid secretion in clinical practice.
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000503:physiopathology; D005744:Gastric Acid / Q000378:metabolism*; D005745:Gastric Acidity Determination; D006801:Humans; D007328:Insulin; D008297:Male; D008875:Middle Aged; D010418:Pentagastrin; D010435:Pepsinogens / Q000097:blood*; D014629:Vagotomy, Proximal Gastric
chemical_list: D007328:Insulin; D010435:Pepsinogens; D010418:Pentagastrin
vernacular_title: Le pepsinogène sérique, index de la sécrétion gastrique acide basale et stimulée. Intérêt de son dosage.