[Radical surgical correction of tetralogy of Fallot: comparison between the effects of isoproterenol in IPPV and spontaneous-ventilation after surgical treatment (author's transl)].
The AA. studied 7 patients affected by Tetralogy of Fallot; their ages were between 4 and 20 years. At the end of the radical surgical correction we studied their haemodynamics. From the analysis of the data we found that using beta-agonist drugs (Isuprel 0.05 mcg x Kg x min) there were no change in the haemodynamic data when the patients were kept under positive pressure ventilation. In spontaneous ventilation we observed that the same data can raise the cardiac index of 22%, lower the total peripheral resistances (20%) and the pulmonary vascular resistances (8%) and the intrapulmonary shunt (8%).
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation; D007545:Isoproterenol / Q000008:administration & dosage*; D008297:Male; D011175:Positive-Pressure Respiration; D011182:Postoperative Care; D012119:Respiration / Q000187:drug effects*; D013771:Tetralogy of Fallot / Q000601:surgery*
D007545:Isoproterenol
Correzione radicale di tetralogia di Fallot: confronto degli effetti dell'isoproterenolol in IPPV e respiro spontaneo nel trattamento postoperatorio immediato.