title: [Use of electrodense metals in transmission electron microscopy technology].
abstract: Metalloboranes could serve perspectively as carriers of electrodense metals for electron microscopy, because they penetrate into tissues and are linked to them. The tested brominated cobaltacarborane anion, however, did not by far meet the demands of standard quality electronograms, as in combination with aldehyde fixation they give a low contrast of protein and nucleoprotein structures and contrary to osmium tetroxide they does not mark membrane lipids; it did not prove useful for contrasting of epoxide sections. The results, however, stimulate the seeking of more suitable boranes substituted with metals with a higher atomic number and a different molecular configuration.
mesh_terms: D000818:Animals; D001896:Boron Compounds; D003035:Cobalt; D006652:Histological Techniques; D008099:Liver / Q000648:ultrastructure; D008854:Microscopy, Electron / Q000379:methods*; D051381:Rats; D000098851:Carboranes
chemical_list: D001896:Boron Compounds; D003035:Cobalt; C013590:bis(tribromocarboranyl)cobaltate; D000098851:Carboranes
vernacular_title: Nové moznosti aplikace elektrodenzních kovů pro technologii transmisní elektronové mikroskopie.