Metabolic modification by insulin enhances methotrexate cytotoxicity in MCF-7 human breast cancer cells.
D001943:Breast Neoplasms / Q000378:metabolism*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects*; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D006801:Humans; D007328:Insulin / Q000494:pharmacology*; D008727:Methotrexate / Q000633:toxicity*; D009374:Neoplasms, Experimental / Q000378:metabolism
D007328:Insulin; D008727:Methotrexate