title: Historical aspects of normal and abnormal brain fluids. III. Cerebral edema.
abstract: The early life, death, and revival of the concept of cerebral edema are discussed. This unusual sequence has been related to a clinical syndrome, a vascular hypothesis, a unique brain circulation, and a new investigative technique: electron microscopy.
mesh_terms: D001812:Blood-Brain Barrier; D001929:Brain Edema / Q000266:history* / Q000378:metabolism / Q000473:pathology; D002555:Cerebrospinal Fluid; D002560:Cerebrovascular Circulation; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D010539:Permeability