title: [Influence of adrenaline on the transmembrane potential changes in developing loach embryos].
abstract: Changes of transmembrane potential (TMP) in loach embryos developing for 7--8 hours in the medium supplemented with different adrenalin concentrations and in its mixtures with insulin or actinomycin D are studied. It was shown that value and mode of TMP changes, and its depolarizing effect and removal of periodic TMP oscillations in particular, which coincided with normal cycles of synchronous blastomere divisions depended on adrenalin level in the medium. Actinomycin D gradually eliminated the adrenalin influence on embryos only in the second half of the above mentioned period of their development, whereas insulin exerted its effect already at the early stages of embryogenesis.
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D003609:Dactinomycin / Q000494:pharmacology; D004625:Embryo, Nonmammalian / Q000187:drug effects / Q000502:physiology*; D004837:Epinephrine / Q000494:pharmacology*; D005399:Fishes; D007328:Insulin / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects
chemical_list: D007328:Insulin; D003609:Dactinomycin; D004837:Epinephrine
vernacular_title: Vliianie adrenalina na dinamiku transmembrannogo petentsiala razvivaiushchikhsia zarodysheĭ v'iuna.