title: Immunotoxicology in the pharmaceutical industry.
abstract: Development of an immunotoxicology program within the pharmaceutical industry is described. With few guidelines in the area and a multitude of factors to consider, a basic screen for evaluating immune competence in species routinely used in toxicologic studies has been proposed. The future of immunotoxicology depends upon the ability of the selected immune function tests to be predictive of human risk.
mesh_terms: D000818:Animals; D003520:Cyclophosphamide / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004345:Drug Industry; D007109:Immunity / Q000187:drug effects*; D007121:Immunocompetence / Q000187:drug effects; D007136:Immunoglobulins / Q000032:analysis; D007158:Immunologic Techniques; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D051381:Rats; D014116:Toxicology
chemical_list: D007136:Immunoglobulins; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide