Aspergillus nidulans as a test organism for chemical mutagens.
In the 3 strains of Aspergillus nidulans used, BC reduced survival most and 4HMB least. Similar trends were found when the effect on gene conversion was studied in a diploid strain and point mutation was scored in a haploid strain. None of the compounds had any effect on mitotic segregation.
D001233:Aspergillus nidulans / Q000187:drug effects*; D001593:Benzyl Compounds / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology*; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology*; D009154:Mutation; D013329:Structure-Activity Relationship
D001593:Benzyl Compounds; D001713:Biphenyl Compounds; D009153:Mutagens; C033488:4-hydroxymethylbiphenyl; C033487:4-chloromethylbiphenyl; C021292:benzyl chloride