title: beta-methylnorleucine, an antimetabolite produced by Serratia marcescens.
abstract: An amino acid was formed by alpha-aminobutyrate-resistant mutants of Serratia marcescens grown in a medium containing norvaline. This amino acid was identified as erythro-beta-methyl-L-norleucine [(2S,3S)-2-amino-3-methylhexanoic acid] by instrumental analyses. beta-Methylnorleucine inhibited the growth of several bacteria in synthetic medium.
mesh_terms: D000614:Aminocaproates / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000963:Antimetabolites / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D009646:Norleucine / Q000031:analogs & derivatives / Q000302:isolation & purification* / Q000494:pharmacology; D012706:Serratia marcescens / Q000378:metabolism*
chemical_list: D000614:Aminocaproates; D000900:Anti-Bacterial Agents; D000963:Antimetabolites; C032957:beta-methylnorleucine; D009646:Norleucine