Passage through the lymph node. II. Functional dependence on the site of application of antigens.
Following a previous comment on the compartmentalization of lymph nodes by lymphography performed through separate bundles of afferent lymphatics, the authors attempted to prove that sectoral arrangement has its functional equivalent, too. They found an elective uptake of tritiated thymidine and a rather circumscript response in cellular activity, if antigenic stimuli--such as VX-2 carcinoma cells and living BCG  colonies--were transferred through the same bundle of afferent lymphatics which supply the lymph node part investigated.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D002460:Cell Line; D007109:Immunity; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D008220:Lymphography; D009163:Mycobacterium bovis / Q000276:immunology*; D009374:Neoplasms, Experimental / Q000473:pathology; D011817:Rabbits; D013936:Thymidine / Q000378:metabolism
D013936:Thymidine