A comparative study of the efficacy of indapamide and bendrofluazide given in combination with atenolol.
In a double blind crossover double dummy study, 17 hypertensive patients who were not adequately controlled on atenolol alone were additionally given either bendrofluazide 5 mg or indapamide 2.5 mg for 12 weeks. Both drugs produced a similar modest improvement in blood pressure. No differences were seen on either treatment in body weight, plasma electrolytes, urea or uric acid.
D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001262:Atenolol / Q000627:therapeutic use*; D001539:Bendroflumethiazide / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007190:Indapamide / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D011412:Propanolamines / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D004232:Diuretics; D011412:Propanolamines; D001262:Atenolol; D001539:Bendroflumethiazide; D007190:Indapamide