Skeletal-muscle alpha-glucosidases in bovine generalized glycogenosis type II.
The skeletal muscle of cattle suffering from generalized glycogenosis type II was shown to lack acid alpha-glucosidase (EC 3.2.1.3) activity. Furthermore, there was no evidence of enzymically inactive proteins that cross-reacted with antibodies raised against acid alpha-glucosidase from the muscle of normal animals.
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000201:enzymology*; D002852:Chromatography, Ion Exchange; D005959:Glucosidases / Q000378:metabolism*; D006008:Glycogen Storage Disease / Q000662:veterinary*; D006009:Glycogen Storage Disease Type II / Q000201:enzymology / Q000662:veterinary*; D007106:Immune Sera; D009132:Muscles / Q000201:enzymology*; D000520:alpha-Glucosidases / Q000276:immunology / Q000378:metabolism*
D007106:Immune Sera; D005959:Glucosidases; D000520:alpha-Glucosidases