title: The prevention of pain on injection. A study of the effect of intravenous lignocaine before methohexitone.
abstract: The effect of pre-injection of lignocaine 10 mg or physiological saline was assessed in a double blind trial on 100 unpremedicated day cases having a methohexitone induction. The incidence of pain was reduced from 64% to 22% using lignocaine.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008012:Lidocaine / Q000627:therapeutic use*; D008297:Male; D008723:Methohexital / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control*; D011229:Preanesthetic Medication; D011897:Random Allocation; D013997:Time Factors
chemical_list: D008012:Lidocaine; D008723:Methohexital