Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits.
D015121:6-Ketoprostaglandin F1 alpha / Q000096:biosynthesis*; D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000378:metabolism; D001013:Aorta, Thoracic / Q000378:metabolism; D001792:Blood Platelets / Q000187:drug effects* / Q000502:physiology; D001808:Blood Vessels / Q000187:drug effects*; D002784:Cholesterol / Q000097:blood; D002866:Chromonar / Q000031:analogs & derivatives*; D003374:Coumarins / Q000494:pharmacology*; D011464:Epoprostenol / Q000378:metabolism; D006937:Hypercholesterolemia / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D013929:Thromboxane B2 / Q000378:metabolism
D003374:Coumarins; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D002784:Cholesterol; C025945:cloricromen; D011464:Epoprostenol; D002866:Chromonar