title: Comparison of bupivacaine, etidocaine, and saline for trigger-point therapy.
abstract: Injections of local anesthetics, saline, "dry needling," or other stimuli at specific, tender loci (trigger or acupuncture points) are reportedly efficacious in treatment of chronic pain syndromes. In a randomized, double-blind crossover study, subjective responses of 15 patients with myofascial syndrome to trigger-point injections of either bupivacaine 0.5%, etidocaine 1%, or physiologic saline without preservative were compared. Responses in six pain-related categories were determined before treatment and 15 minutes, 24 hours, and 7 days after treatment. Trigger-point injections with bupivacaine and etidocaine were generally preferred over saline in several pain-tested categories. Implications and possible mechanisms are discussed.
mesh_terms: D000083:Acetanilides / Q000008:administration & dosage; D002045:Bupivacaine / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005041:Etidocaine / Q000008:administration & dosage; D006801:Humans; D007267:Injections; D009209:Myofascial Pain Syndromes / Q000503:physiopathology*; D059408:Pain Management; D011897:Random Allocation; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000083:Acetanilides; D012965:Sodium Chloride; D005041:Etidocaine; D002045:Bupivacaine