Cloning of the regulatory genes (ompR and envZ) for the matrix proteins of the Escherichia coli outer membrane.
We have cloned the regulatory gene cluster of Escherichia coli which is composed of at least two distinct genes, ompR and envZ. These genes are known to regulate the production of the outer membrane matrix proteins. The newly formed plasmids were found to complement not only ompR mutations but also envZ mutations. The ompR gene product was identified as a protein of an apparent molecular weight of 28,500.
D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000235:genetics*; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics*; D005798:Genes, Bacterial; D005809:Genes, Regulator; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D010957:Plasmids; D013489:Suppression, Genetic
D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D008565:Membrane Proteins