The biological activity of the synthetic polyanion, pyran copolymer (diveema, MVE, 46015) and the heterocyclic bis DEAE fluorenone derivative, tilorone and congeners: clinical and laboratory effects of these agents as modulators of host resistance.
D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000925:Anticoagulants / Q000494:pharmacology; D002467:Cell Nucleus / Q000187:drug effects; D003593:Cytoplasm / Q000187:drug effects; D005449:Fluorenes / Q000494:pharmacology*; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects*; D007369:Interferon Inducers / Q000494:pharmacology; D008262:Macrophage Activation / Q000187:drug effects; D009369:Neoplasms / Q000188:drug therapy; D009696:Nucleic Acids / Q000378:metabolism; D011108:Polymers / Q000494:pharmacology*; D011713:Pyran Copolymer / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D013994:Tilorone / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity
D000276:Adjuvants, Immunologic; D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D005449:Fluorenes; D007369:Interferon Inducers; D009696:Nucleic Acids; D011108:Polymers; D011713:Pyran Copolymer; D013994:Tilorone