Distribution of blood group antigens A, B and H in ameloblastomas.
The histologic distribution of blood group antigens, A, B and H was examined in ameloblastomas and normal mucosa from 15 patients. The blood group antigens were demonstrated with a semiquantitative immunofluorescence staining method. Blood group antigens A and B were absent in the ameloblastomas, whereas the spinous cells of the oral mucosal epithelium showed a positive reaction in correspondence with the patient's blood group. Blood group antigen H was demonstrated in 14 of 15 ameloblastomas from patients belonging to blood group A, B, AB or O. In the oral mucosal epithelium from these patients blood group antigen H in all cases was located to the cell membranes of the spinous cells. The present findings suggest that a difference in ability to synthesize blood groups antigen H and the blood group antigens A and B exists in the ameloblastoma.
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000368:Aged; D000564:Ameloblastoma / Q000097:blood*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000032:analysis; D009062:Mouth Neoplasms / Q000097:blood*
D000017:ABO Blood-Group System