[Renal siderosis in cardiac hemolysis].
Renal siderosis caused by intravasal haemolysis has been studied in 202 autopsy cases, which based on the origin of the intravasal haemolysis have been divided into three groups: 1. patients deceased months or years after artificial valve implantation; 2. patients with congenital or acquired defective heart valves without surgical treatment; 3. patients deceased several days after open heart surgery. Renal siderosis has been detected by prussian-blue staining method. In 1/3 of the cases quantitative determination of the iron content has also been carried out. In cases of chronic defective heart valves without an operation renal siderosis has not developed. Among patients, who underwent open-heart operation it has been observed only in one case. After valvular replacement-except one case-renal siderosis developed only in patients with valvular failure. These findings seem to indicate that unless rare exceptions renal siderosis develops only in cases of long lasting intravasal haemolysis.
D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006461:Hemolysis; D006485:Hemosiderin / Q000032:analysis; D006652:Histological Techniques; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D007687:Kidney Tubules, Proximal / Q000032:analysis / Q000648:ultrastructure; D012806:Siderosis / Q000209:etiology* / Q000473:pathology
D006485:Hemosiderin
Renalis siderosis cardialis haemolysisben.