[Oxidative and antioxidative system of the blood in mechanisms of erythrocyte protection and damage upon invasion by Plasmodium berghei].
In the course of experimental infection with Pl. Berghei, the mice demonstrated an abrupt lowering in the activity of blood enzymes (superoxide dismutase and glutathione peroxidase) and a rise in the concentration of the lipid peroxidation product (malonic dialdehyde) with the growth of parasitemia. The evidence obtained are discussed in the light of the defence and injury blood mechanisms of red cell membranes.
D000818:Animals; D004912:Erythrocytes / Q000378:metabolism* / Q000469:parasitology; D005979:Glutathione Peroxidase / Q000097:blood; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008288:Malaria / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D051379:Mice; D008807:Mice, Inbred BALB C; D010962:Plasmodium berghei; D013482:Superoxide Dismutase / Q000097:blood
D008054:Lipid Peroxides; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
Okislitel'naia i antiokislitel'naia sistema krovi v mekhanizmakh zashchity i povrezhdeniia éritrotsitov myshi pri invazii Plasmodium berghei.