[Effect of immunodepressive therapy with azathioprine and prednisolone on the individual serum protein content in chronic kidney failure patients after a kidney allograft].
The immunodepressants azathioprine and prednisolone given to patients after kidney transplantation decreased the concentration of IgG, IgA, and IgM. Azathioprine and prednisolone did not affect the content of C3c and C4 components of complement in patients after kidney transplantation. Prednisolone coupled with azathioprine reduced the toxic action of the latter and raised the concentration of alpha 1-glycoprotein, alpha 2-macroglobin, transferrin, haptoglobin which are responsible for nonspecific defence factors.
D000293:Adolescent; D000328:Adult; D001379:Azathioprine / Q000276:immunology / Q000627:therapeutic use*; D001798:Blood Proteins / Q000032:analysis*; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D016030:Kidney Transplantation; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods; D011239:Prednisolone / Q000276:immunology / Q000627:therapeutic use*
D001798:Blood Proteins; D011239:Prednisolone; D001379:Azathioprine
Vliianie immunodepressivnoĭ terapii azatioprinom i prednizolonom na soderzhanie individual'nykh syvorotochnykh belkov u bol'nykh khronicheskoĭ pochechnoĭ nedostatochnost'iu posle allotransplantatsii pochki.