The cloacin receptor of ColV-bearing Escherichia coli is part of the Fe3+-aerobactin transport system.
Escherichia coli strains which contain the Fe3+-aerobactin transport system specified by the ColV plasmid became deficient in aerobactin-dependent iron transport when they were converted to cloacin-resistant derivatives. An outer membrane protein with a molecular mass of 74,000 daltons was overproduced under iron-limiting growth conditions and was absent in cloacin-resistant mutants. Fe3+-aerobactin protected cells against cloacin. These results suggest that the cloacin receptor protein, controlled by the colV plasmid, also participates in Fe3+-aerobactin transport.
D001425:Bacterial Outer Membrane Proteins; D003086:Bacteriocin Plasmids; D001430:Bacteriocins / Q000494:pharmacology*; D001692:Biological Transport; D002989:Cloacin / Q000494:pharmacology*; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D005290:Ferric Compounds / Q000378:metabolism*; D006877:Hydroxamic Acids / Q000378:metabolism*; D007501:Iron / Q000378:metabolism*; D011971:Receptors, Immunologic / Q000502:physiology*
D001425:Bacterial Outer Membrane Proteins; D001430:Bacteriocins; D005290:Ferric Compounds; D006877:Hydroxamic Acids; D011971:Receptors, Immunologic; C034506:aerobactin receptor; C031819:aerobactin; D002989:Cloacin; D007501:Iron