title: Pharmacokinetic studies: their role in determining therapeutic efficacy of agents designed to prevent sudden death.
mesh_terms: D000284:Administration, Oral; D000889:Anti-Arrhythmia Agents / Q000097:blood / Q000627:therapeutic use*; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D003645:Death, Sudden / Q000209:etiology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007263:Infusions, Parenteral; D007700:Kinetics; D008012:Lidocaine / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000401:mortality; D010880:Piperidines / Q000097:blood / Q000627:therapeutic use; D011433:Propranolol / Q000031:analogs & derivatives / Q000097:blood / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D010880:Piperidines; C001422:4-hydroxypropranolol; D008012:Lidocaine; D011433:Propranolol; C024318:pirmenol