Co-translational insertion of envelope proteins: theoretical consideration and implications.
In this paper we examine some of the quantitative consequences of co-translational insertion of outer membrane proteins (OMP). Due to the linkage of OMP-synthesizing polysomes to the cell envelope, the whole machinery involved in the synthesis of OMP must necessarily be membrane-bound and dynamic. Implications of the model are discussed.
D001426:Bacterial Proteins / Q000096:biosynthesis*; D002462:Cell Membrane / Q000378:metabolism; D004269:DNA, Bacterial / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D008565:Membrane Proteins / Q000096:biosynthesis*; D009154:Mutation; D011132:Polyribosomes / Q000378:metabolism; D014176:Protein Biosynthesis
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D008565:Membrane Proteins