Xerostomia in Sjögren's syndrome treated with Sali-Synt. A double-blind cross-over trial.
In a double-blind cross-over trial, a new synthetic saliva Sali-Synt was compared with placebo for the treatment of xerostomia in Sjögren's syndrome. Sali-Synt may soothe the pain in the mouth and reduces sleep disturbances better than placebo, but no statistically significant differences were found. Seven patients of 12 preferred Sali-Synt to placebo in helping xerostomia.
D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D012463:Saliva; D012859:Sjogren's Syndrome / Q000150:complications*; D012996:Solutions / Q000627:therapeutic use*; D014987:Xerostomia / Q000188:drug therapy* / Q000209:etiology
C033867:Sali-synt; D012996:Solutions