title: Lack of mutagenicity of the fungicide 2,4,5,6-tetrachloroisophthalonitrile in the Ames Salmonella microsome test.
abstract: The fungicide 2,4,5,6-tetrachloroisophthalonitrile was found to be not mutagenic to five Salmonella typhimurium tester strains. Incorporation of either a liver or a kidney activation system did not increase the mutagenic activity of the fungicide.
mesh_terms: D002722:Chlorobenzenes / Q000494:pharmacology*; D005659:Fungicides, Industrial / Q000494:pharmacology*; D009152:Mutagenicity Tests; D009153:Mutagens; D009154:Mutation; D009570:Nitriles / Q000494:pharmacology*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics
chemical_list: D002722:Chlorobenzenes; D005659:Fungicides, Industrial; D009153:Mutagens; D009570:Nitriles; C005806:tetrachloroisophthalonitrile