[Comparison of two methods of evaluation of gentamicin in man : bioassay and enzyme immunoassay (author's transl)].
This study compares two methods of gentamicin determination in blood : bioassay and enzyme immunoassay. Results for 145 patients serums showed a correlation coefficient of 0,895 between the two methods. The accuracy and reproducibility were tested on 10 known samples. Each sample was titrated 10 times. Values obtained and real values are near between 0 and 5 mcg/ml and significantly move away between 6 and 10 mcg/ml by the two methods. Advantages and disadvantages are discussed for each method.
D001681:Biological Assay / Q000379:methods; D005839:Gentamicins / Q000097:blood*; D006801:Humans; D007124:Immunoenzyme Techniques
D005839:Gentamicins
Comparaison de deux techniques de dosage de la gentamicine chez l'homme. Méthodes microbiologique et immunoenzymatique.