title: Yeast ochre suppressor SUQ5-ol is an altered tRNA Ser UCA.
abstract: Ochre suppressor tRNA was partially purified from strains of Saccharomyces cerevisiae containing the serine-inserting class III suppressor SUQ5-ol. RNA sequence analysis of this tRNA indicated that the suppressor is derived from a UCA-decoding tRNA Ser by a G leads to U substitution in the middle position of the anticodon. The suppressor further differs from the wild-type UCA-decoding tRNA Ser in that the mutant anticodon lacks the modified uridine found in the wobble position of the wild-type tRNA and contains instead another modification in or near the anticodon.
mesh_terms: D000926:Anticodon / Q000235:genetics; D001483:Base Sequence; D009154:Mutation; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000235:genetics*; D009843:Oligoribonucleotides / Q000235:genetics*; D012343:RNA, Transfer / Q000235:genetics; D012346:RNA, Transfer, Amino Acyl / Q000235:genetics*; D012260:Ribonucleases; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D013045:Species Specificity; D013489:Suppression, Genetic
chemical_list: D000926:Anticodon; D009841:Oligonucleotides; D009843:Oligoribonucleotides; D012346:RNA, Transfer, Amino Acyl; D012343:RNA, Transfer; D012260:Ribonucleases