[Alpha-1-antitrypsin and fibrinogen levels in chronic renal failure and after kidney transplantation (author's transl)].
In ten non dialyzed patients with chronic renal failure, 18 patients on regular dialysis treatment and 70 renal transplant recipients alpha-1-antitrypsin and fibrinogen levels were investigated. Alpha-1-antitrypsin and fibrinogen concentrations were highest in dialyzed patients with values of 314 +/- 98 and 485 +/- 127 mg/dl respectively. In renal transplant recipients a significant positive correlation between alpha-1-antitrypsin and fibrinogen concentration was found (p less than 0.001). High alpha-1-antitrypsin and fibrinogen levels seem to be a possible consequence of reactive processes due to underlying disease or complications. Our results seem to indicate that both alpha 1-antitrypsin and fibrinogen can be classified as "acute phase protein".
D003404:Creatinine / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006084:Graft Rejection; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D016030:Kidney Transplantation; D008297:Male; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
D000515:alpha 1-Antitrypsin; D005340:Fibrinogen; D003404:Creatinine
Alpha-1-Antitrypsin und Fibrinogenspiegel bei chronischer Niereninsuffizienz und nach Nierentransplantation.