[ds-DNA- and denaturized ds-DNA auto-antibodies in old age and their pathological determination (author's transl)].
The antibodies of 50 old people of the age over 70 years were determined against ds-DNA and denaturized ds-DNA by the immune-fluorescence method, and it can be stated that denaturized ds-DNA antibodies are traceable in 16% of these sera. Such antibodies could not be found in control tests of seras of young people. However, the old people did not show may clinical symptom typical of the disease caused by these antibodies. In particular, there were no indications of an auto-immune disease, for that reason, these antibodies are to be considered as optional pathological ones.
D000368:Aged; D000375:Aging; D000906:Antibodies / Q000032:analysis*; D004247:DNA / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans
D000906:Antibodies; D004247:DNA
Nachweis von ds-DNS- und UV-denaturierten ds-DNS-Autoantikör-pern bei alten Menschen und ihre pathogentische Bedeutung.