title: Specific red cell adherence test and unspecific immune response in patients with superficial bladder cancer.
abstract: ABH antigenicity and unspecific immune response were evaluated in 31 patients with superficial transitional cell carcinoma. 26% of these patients showed a reduced dinitrochlorobenzene (DNCB) reaction. There was no significant difference in the monocyte chemotaxis of patients with benign urological diseases and patients with superficial bladder cancer. However, a significant difference exists versus patients with deeply infiltrating carcinomas. 20 patients revealed a loss of ABH antigens on the initial tumor. During the follow-up of at least 1 year, patients with negative DNCB skin test, reduced monocyte chemotaxis and negative specific red cell adherence test demonstrated a high rate of recurrent tumors and in 1 of 7 a progressive tumor developed.
mesh_terms: D000368:Aged; D002278:Carcinoma in Situ / Q000276:immunology*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D002634:Chemotaxis, Leukocyte; D004137:Dinitrochlorobenzene / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D009000:Monocytes / Q000276:immunology; D012882:Skin Tests; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
chemical_list: D004137:Dinitrochlorobenzene