Equivalence of topical clobetasone and dexamethasone in experimental corneal allograft rejection.
We produced experimental immune reactions by exchanging peripheral corneal transplants between rabbits. Clobetasone butyrate 0.1% and dexamethasone phosphate 0.1% eye drops were equally effective in delaying corneal allograft rejection.
D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002990:Clobetasol / Q000031:analogs & derivatives / Q000494:pharmacology; D003315:Cornea / Q000276:immunology; D016039:Corneal Transplantation; D003907:Dexamethasone / Q000494:pharmacology; D006084:Graft Rejection / Q000187:drug effects*; D011817:Rabbits
D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; C010893:clobetasone butyrate; D002990:Clobetasol