Twenty-four- and 48-hour canine liver preservation by simple hypothermia with prostacyclin.
Canine livers were preserved by simple hypothermic storage using modified Sacks' solution and prostacyclin. Orthotopic liver transplantation was then carried out. Five of six and three of five livers preserved for 24 and 48 hours, respectively, were able to sustain life for more than five days.
D000818:Animals; D004285:Dogs; D011464:Epoprostenol / Q000494:pharmacology*; D005260:Female; D006982:Hypertonic Solutions; D007036:Hypothermia, Induced; D007552:Isotonic Solutions / Q000494:pharmacology; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation; D008297:Male; D009926:Organ Preservation / Q000379:methods*; D009929:Organ Size; D011453:Prostaglandins / Q000494:pharmacology*; D000077325:Ringer's Lactate; D014021:Tissue Preservation / Q000379:methods*
D006982:Hypertonic Solutions; D007552:Isotonic Solutions; D011453:Prostaglandins; D000077325:Ringer's Lactate; C027821:Sack's solution; D011464:Epoprostenol