title: Adjuvant chemotherapy in colon and gastric cancer.
abstract: The adjuvant chemotherapy of colorectal and gastric cancer is being actively investigated. Studies of both single antineoplastic agents and combinations of several drugs have been used. In colorectal cancer, single-agent therapy has not resulted in improved survival. Combination chemotherapy studies are at too early a stage to be evaluated. In gastric cancer, single-agent chemotherapy has not been effective as adjunctive treatment to surgery. Combinations of active agents in gastric cancer hold promise as effective surgical adjuvant therapy.
mesh_terms: D001500:BCG Vaccine / Q000276:immunology; D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000628:therapy; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007167:Immunotherapy; D009163:Mycobacterium bovis / Q000276:immunology; D012673:Semustine / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000188:drug therapy*
chemical_list: D001500:BCG Vaccine; C011499:methanol extraction residue (MER) tubercle bacillus fraction; D012673:Semustine; D005472:Fluorouracil