title: [About the value of adjuvant chemotherapy in advanced cervical cancer. First results of a prospective randomised study (author's transl)].
abstract: It was reported on a prospective randomised study of cervical cancer with lymphonodus involvement. After operation and radiotherapy twenty three women were treated with an additional adjuvant chemotherapy by using cyclophosphamide, methotrexate and vincristine for a period of 30 weeks. According to the first results obtained there is no significant difference as against the control group. In this publication the generally unsatisfactory results of the chemotherapy of cervical cancer have been outlined.
mesh_terms: D002584:Cervix Uteri / Q000601:surgery*; D002986:Clinical Trials as Topic; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D011897:Random Allocation; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014750:Vincristine / Q000627:therapeutic use*
chemical_list: D014750:Vincristine; D003520:Cyclophosphamide; D008727:Methotrexate
vernacular_title: Zum Wert einer adjuvanten Chemotherapie beim fortgeschrittenen Zervixkarzinom. Erste Ergebnisse einer prospektiv-randomisierten Studie.