title: Mutagenic activity of caffeinated and decaffeinated coffee.
abstract: Two types of coffee (caffeinated and decaffeinated) were tested for their mutagenicity using bacterial strains using TA98 and TA100 in Ames Salmonella/Microsome test. According to the Ames criteria, both were found to be mutagenic in the absence of S-9. The mutagens did not require liver enzymes to be activated.
mesh_terms: D002110:Caffeine / Q000633:toxicity*; D003069:Coffee / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D009153:Mutagens; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics
chemical_list: D003069:Coffee; D009153:Mutagens; D002110:Caffeine