title: Adverse effects of cardiovascular drug therapy on the fetus and neonate.
abstract: Possible adverse effects of cardiovascular medications on the fetus and the neonate have been reviewed. The major classes discussed were diuretics, antihypertensives, antiarrhythmics, cardiac glycosides, and anticoagulants. The recommendations given must not be considered definitive because they are based on flawed or incomplete information. It is to be hoped that further investigation will improve this situation and will also improve our understanding of the ways in which these drugs act.
mesh_terms: D000014:Abnormalities, Drug-Induced; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000009:adverse effects; D002301:Cardiac Glycosides / Q000009:adverse effects; D002317:Cardiovascular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003374:Coumarins / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005317:Fetal Growth Retardation / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D002301:Cardiac Glycosides; D002317:Cardiovascular Agents; D003374:Coumarins; D004232:Diuretics; D006493:Heparin