title: Cell culture studies on patients with extreme insulin resistance. I. Receptor defects on cultured fibroblasts.
mesh_terms: D000052:Acanthosis Nigricans / Q000378:metabolism*; D000293:Adolescent; D000328:Adult; D001667:Binding, Competitive; D002478:Cells, Cultured; D004392:Dwarfism / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007223:Infant; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance; D007335:Insulin-Like Growth Factor II; D007700:Kinetics; D010455:Peptides / Q000378:metabolism; D011972:Receptor, Insulin / Q000276:immunology / Q000378:metabolism*; D013002:Somatomedins / Q000378:metabolism; D013577:Syndrome
chemical_list: D007328:Insulin; D010455:Peptides; D013002:Somatomedins; D007335:Insulin-Like Growth Factor II; D011972:Receptor, Insulin