title: [Flurbiprofen and indomethacin in chronic polyarthritis and gonarthrosis - a comparative multicentric double-blind cross-over study].
abstract: In two multicenter double-blind cross-over studies efficacy and safety of flurbiprofen and indomethacin were compared. Nineteen patients with rheumatoid arthritis and twenty with osteoarthrosis of the knee were treated. Both drugs were effective and almost equal. Also safety was good, however three patients on indomethacin and one on flurbiprofen had to be withdrawn from the trial because of side-effects.
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D007719:Knee Joint / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000187:drug effects; D011422:Propionates / Q000627:therapeutic use*
chemical_list: D011422:Propionates; D005480:Flurbiprofen; D007213:Indomethacin
vernacular_title: Flurbiprofen und Indometacin bei chronischer Polyarthritis und Gonarthrose --eine vergleichende multizentrische Doppelblind-cross-over-Studie.