[Effect of 60Co gamma rays and fast neutrons on intravascular platelet aggregation and vessel wall prostacyclin activity].
The influence of gamma-rays 60Co and fast neutrons on intravascular platelet aggregation and prostacyclin activity of the vascular wall has been studied. It has been shown that 1-6 hours after irradiation of CBA mice, a great number of bone marrow platelets clump to form fibrin fibrils that often close completely the vascular lumen. Experiments with irradiated rats and guinea-pigs have demonstrated the reduction of prostacyclin-like activity in the abdominal aorta wall.
D000818:Animals; D001011:Aorta / Q000528:radiation effects; D001808:Blood Vessels / Q000528:radiation effects*; D003037:Cobalt Radioisotopes; D011464:Epoprostenol / Q000528:radiation effects*; D005214:Fast Neutrons; D005720:Gamma Rays; D006168:Guinea Pigs; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009502:Neutrons; D010974:Platelet Aggregation / Q000528:radiation effects*; D011453:Prostaglandins / Q000528:radiation effects*
D003037:Cobalt Radioisotopes; D011453:Prostaglandins; D011464:Epoprostenol
Vliianaie gamma-lucheĭ 60Co i bystrykh neĭtronov na vnutrisosudistuiu agregatsiiu trombotsitov i prostatsiklinovuiu aktivnost' stenki sosudov.