title: Development of statistical analysis for single dose bronchodilators.
abstract: When measurements developed for the diagnosis of patients are used to detect treatment effects in clinical trials with chronic disease, problems in definition of response and in the statistical distributions of those measurements within patients have to be resolved before the results of clinical studies can be analyzed. An example of this process is shown in the development of the analysis of single-dose bronchodilator trials.
mesh_terms: D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic / Q000379:methods; D004983:Ethanolamines / Q000627:therapeutic use; D005541:Forced Expiratory Volume; D006801:Humans; D012107:Research Design; D013147:Spirometry; D013223:Statistics as Topic
chemical_list: D001993:Bronchodilator Agents; D004983:Ethanolamines; C009118:pirbuterol