DNA synthesis in Escherichia coli during a nutritional shift-up.
DNA synthesis in a thymine-requiring Escherichia coli K12 strain was studied by exploiting deoxyguanosine, so simulating the behaviour of Thy+ strains. DNA synthesis is inhibited during the first 24 min after a nutritional shift-up. The new DNA/mass is lower than that predicted by current models for initiation control.
D002455:Cell Division; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004926:Escherichia coli / Q000254:growth & development / Q000378:metabolism*; D013997:Time Factors
D004269:DNA, Bacterial