title: Radiographic tracheal diameter measurements in acute infectious croup: an objective scoring system.
abstract: The percentage of change in tracheal diameter (TD% change), as assessed by an objective radiological measurement, was used along with a simple subjective clinical score to assess response to therapy in upper airway obstruction in 14 patients with acute infectious croup. Studies were performed on the 14 patients, each of whom was randomly assigned to one of two treatment groups: distilled water or racemic epinephrine (RE), both being nebulized and delivered by manual IPPB. The objective radiological assessment and the subjective clinical score both confirmed that RE is significantly (p less than 0.005) more effective than distilled water in the acute relief of upper airway obstruction. The more precise radiological assessment may be of value in determining objectively better drug therapy for infectious croup.
mesh_terms: D000402:Airway Obstruction / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003440:Croup / Q000628:therapy*; D004837:Epinephrine / Q000627:therapeutic use*; D006801:Humans; D007827:Laryngitis / Q000628:therapy*; D064705:Racepinephrine; D011859:Radiography; D012138:Respiratory Therapy / Q000592:standards*; D014132:Trachea / Q000000981:diagnostic imaging / Q000473:pathology*; D014867:Water / Q000627:therapeutic use*
chemical_list: D014867:Water; D064705:Racepinephrine; D004837:Epinephrine