[Automatic cytodiagnostic of bladder cancer (author's transl)].
Searching for bladder cancer, 1268 flow-through-cytophotometric determinations of DNA in nuclei of cells were done using the ICP 11. 134 urines (36.2%) and 15 bladder washings (2.9%) could not be evaluated. The examination of urines led to a right positive diagnosis in 56.7%. The corresponding values in wash-out material and biopsy specimen were 61.2% and 75.3%. False positive results were found of 32.5% of the urines, 6.2% of the wash-out fluid and 9.1% in the biopsy specimens. The results are slightly less advantageous than those of conventional cytodiagnostic. Using a special way in selecting the results, false positive values could be eliminated. By this the tentative diagnosis of cancer gained by flow-through-cytophotometry, could be estimated to be correct in a high percentage. It seems that the flow-through-cytophotometry carried out as additional morphological test is an improvement in diagnosis and grading as well as in estimating prognosis and therapeutic results of urological cancer.
D001322:Autoanalysis; D003584:Cytological Techniques; D004273:DNA, Neoplasm / Q000032:analysis; D005069:Evaluation Studies as Topic; D005189:False Positive Reactions; D006801:Humans; D010783:Photometry / Q000379:methods; D007507:Therapeutic Irrigation; D001743:Urinary Bladder / Q000166:cytology*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*; D014556:Urine / Q000166:cytology
D004273:DNA, Neoplasm
Untersuchungen zur Automatisierung der Zytodiagnostik des Harnblasenkarzinoms.