Experimental studies on a new hair dyeing ingredient 2-(2', 4'-diaminophenoxy) ethanol : lack of genotoxic properties.
A benzene metadiamine derivative, 2-(2', 4' diaminophenoxy) ethanol proved to be interesting in hairdyeing. Its genotoxicity was investigated in various tests. The ingredient showed no mutagenicity in the different assays which indicates a correlation among the battery of tests. It also appears that within a chemical category, similarity of structure does not always imply similar genetic response.
D000818:Animals; D002869:Chromosome Aberrations; D004260:DNA Repair / Q000187:drug effects; D005796:Genes / Q000187:drug effects; D006202:Hair Dyes / Q000633:toxicity*; D006203:Hair Preparations / Q000633:toxicity*; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens; D010655:Phenylenediamines / Q000633:toxicity*; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics
D006202:Hair Dyes; D006203:Hair Preparations; D009153:Mutagens; D010655:Phenylenediamines; C032556:2-(2',4'-diaminophenoxy)ethanol