Transient anuria following administration of angiotensin I-converting enzyme inhibitor (SQ 14225) in a patient with renal artery stenosis of the solitary kidney successfully treated with renal autotransplantation.
We report on a patient with renal artery stenosis who had only 1 kidney and in whom acute renal impairment developed with transient anuria after the administration of captopril. Although inhibition of the angiotensin-converting enzyme is considered to be efficient treatment for hypertension associated with chronic renal failure, care should be taken when captopril is administered initially to a patient with decreased renal function, under the conditions of sodium and water depletion. The renovascular hypertension in this patient was treated successfully by renal autotransplantation.
D000328:Adult; D001002:Anuria / Q000209:etiology* / Q000628:therapy; D002216:Captopril / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D016030:Kidney Transplantation; D008297:Male; D011392:Proline / Q000031:analogs & derivatives*; D012078:Renal Artery Obstruction / Q000188:drug therapy* / Q000628:therapy; D013997:Time Factors
D011392:Proline; D002216:Captopril