title: Assessment of a new device for delivering aerosol drugs to asthmatic children.
abstract: A new device, known as the aero-chamber, for delivering aerosol drugs was compared with a standard aerosol inhaler in asthmatic children aged between 5 years 3 months and 13 years 10 months. The study was conducted under double-blind conditions using fenoterol, a beta 2 stimulant, as the active agent and a placebo. Response to treatment was assessed by measuring the peak expiratory flow rate before and after each inhaler. Seven of 10 children had greater mean improvements in peak expiratory flow rates when receiving the active drug from the aerochamber. The aerochamber offers a method for administering a whole range of canistered packaged drugs to children unable to use the standard inhalers.
mesh_terms: D000293:Adolescent; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004864:Equipment and Supplies; D005280:Fenoterol / Q000627:therapeutic use; D006801:Humans; D010366:Peak Expiratory Flow Rate
chemical_list: D000336:Aerosols; D005280:Fenoterol