Pneumonia and bacteremia caused by a previously undescribed Moraxella-like bacterium.
Immunocompromised patients are frequently subject to unusual infections. We recently treated a renal allograft recipient for pneumonia due to a hitherto undescribed Moraxella-like bacterium which most closely resembles M-5. M-5 has previously been associated in humans only with dog bites and wound infections. The patient responded well to treatment with aminoglycosides and cephalosporins. Susceptibility to these drugs was demonstrated in vitro by a broth dilution technique. On the basis of the known ability of Moraxella species to colonize the oropharynx and the patient's lack of animal exposure, we propose that our patient's illness was secondary to aspiration of colonized oropharyngeal contents.
D000328:Adult; D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008826:Microbial Sensitivity Tests; D009016:Moraxella / Q000302:isolation & purification* / Q000502:physiology; D011014:Pneumonia / Q000382:microbiology*; D018805:Sepsis / Q000382:microbiology*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002511:Cephalosporins