Inhibition of tRNA aminoacylation by ethidium dimer and several other bifunctional intercalators with or without antitumor activity.
D000604:Amino Acyl-tRNA Synthetases / Q000037:antagonists & inhibitors; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001665:Binding Sites; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D004926:Escherichia coli / Q000378:metabolism; D004996:Ethidium / Q000031:analogs & derivatives* / Q000494:pharmacology; D012346:RNA, Transfer, Amino Acyl / Q000096:biosynthesis*; D012441:Saccharomyces cerevisiae / Q000378:metabolism
D000970:Antineoplastic Agents; D003432:Cross-Linking Reagents; D012346:RNA, Transfer, Amino Acyl; C018533:ethidium homodimer; D000604:Amino Acyl-tRNA Synthetases; D004996:Ethidium