Adjuvant chemotherapy in colon and gastric cancer.
The adjuvant chemotherapy of colorectal and gastric cancer is being actively investigated. Studies of both single antineoplastic agents and combinations of several drugs have been used. In colorectal cancer, single-agent therapy has not resulted in improved survival. Combination chemotherapy studies are at too early a stage to be evaluated. In gastric cancer, single-agent chemotherapy has not been effective as adjunctive treatment to surgery. Combinations of active agents in gastric cancer hold promise as effective surgical adjuvant therapy.
D001500:BCG Vaccine / Q000276:immunology; D002986:Clinical Trials as Topic; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000628:therapy; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007167:Immunotherapy; D009163:Mycobacterium bovis / Q000276:immunology; D012673:Semustine / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000188:drug therapy*
D001500:BCG Vaccine; C011499:methanol extraction residue (MER) tubercle bacillus fraction; D012673:Semustine; D005472:Fluorouracil