title: The clinical diagnosis of dapsone resistant leprosy.
abstract: For the early recognition of dapsone resistance, it is essential to regularly examine patients at risk for suspicious new lesions, backed by regular clinical treatment records including smear results. The earlier the recognition and starting on alternative treatment, the better is the response. However, it is not advisable to change treatment without attempting at least clinical confirmation, and endorsing the chart so that the problem is not missed on subsequent occasions.
mesh_terms: D003622:Dapsone / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D006801:Humans; D007918:Leprosy / Q000188:drug therapy* / Q000473:pathology; D009166:Mycobacterium leprae / Q000187:drug effects*; D012867:Skin / Q000473:pathology
chemical_list: D003622:Dapsone