title: Thymic hypoplasia, auto-immune haemolytic anaemia and juvenile pemphigoid in an infant.
abstract: A female infant developed auto-immune haemolytic anaemia and juvenile pemphigoid, and died at the age of 10 months. Autopsy showed evidence of thymic hypoplasia and T lymphocyte deficiency. It was concluded that the two rare auto-immune diseases occurring in this child probably resulted from a lack of T cell regulation of antibody-producing B lymphocytes.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D007223:Infant; D008231:Lymphopenia / Q000150:complications; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000276:immunology; D012872:Skin Diseases, Vesiculobullous / Q000150:complications*; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000002:abnormalities* / Q000276:immunology