Oral mebeverine in barium enema preparation.
A double blind controlled trial to determine the effect of mebeverine (Colofac) pre-medication on the incidence of spasm, pain and discomfort during examination of the colon by double contrast barium enema was carried out. There was a significant reduction in spasm on fluoroscopy and reported pain and discomfort in the mebeverine group. The number of segments of spasm on the radiographs was not significantly reduced.
D001466:Barium Sulfate / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004733:Enema / Q000009:adverse effects; D006801:Humans; D010276:Parasympatholytics / Q000627:therapeutic use*; D010627:Phenethylamines / Q000627:therapeutic use*; D013035:Spasm / Q000517:prevention & control
D010276:Parasympatholytics; D010627:Phenethylamines; D001466:Barium Sulfate; C005096:mebeverine