title: Determinants of tissue aluminum concentration.
abstract: These data taken together might indicate that increased tissue burdens of aluminum begin early in chronic renal disease as a consequence of oral aluminum administration. The initiation of dialysis leads to additional aluminum exposure via dialysate. Elevated endogenous parathyroid hormone levels could further enhance the absorption of orally ingested aluminum and alter tissue distribution of aluminum resulting in high brain aluminum concentration.
mesh_terms: D000535:Aluminum / Q000032:analysis* / Q000097:blood / Q000378:metabolism; D000818:Animals; D001923:Brain Chemistry; D004285:Dogs; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D007674:Kidney Diseases / Q000378:metabolism*; D008824:Michigan; D010281:Parathyroid Hormone / Q000502:physiology; D051381:Rats; D006435:Renal Dialysis / Q000009:adverse effects; D014881:Water Supply / Q000032:analysis
chemical_list: D010281:Parathyroid Hormone; D000535:Aluminum