Maintenance of 3T3-L1 cells in culture media containing saturated fatty acids decreases insulin binding and insulin action.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D003470:Culture Media; D003907:Dexamethasone / Q000494:pharmacology; D005227:Fatty Acids / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism / Q000494:pharmacology*; D051379:Mice; D011972:Receptor, Insulin / Q000187:drug effects / Q000378:metabolism*; D013329:Structure-Activity Relationship
D003470:Culture Media; D005227:Fatty Acids; D007328:Insulin; D003907:Dexamethasone; D011972:Receptor, Insulin