Ocular complications of systemic steroid after renal transplantation and their association with HLA.
The eyes of 62 patients who had received allogenic renal transplants were examined for eye disease. Thirty-six patients were found to have steroid induced cataract. Six patients had ocular hypertension. Twelve patients showed arteriosclerotic changes in their fundi relating to their previous hypertensin. There was no significant difference in HLA type in patients who developed cataract and those who did not. 83.3% of the 6 patients with ocular hypertension had HLA B12 in common. None of the patients had cytomegalic retinitis.
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D002386:Cataract / Q000139:chemically induced; D005128:Eye Diseases / Q000139:chemically induced*; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000276:immunology / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000009:adverse effects*
D006680:HLA Antigens; D011239:Prednisolone; D001379:Azathioprine