title: Complications of surgery for radiotherapy skin damage.
abstract: Complications of modern surgery for radiotherapy skin damage reviewed in 28 patients who had 42 operations. Thin split-thickness skin grafts for ulcer treatment had a 100 percent complication rate, defined as the need for further surgery. Local flaps, whether delayed or not, also had a high rate of complications. Myocutaneous flaps for ulcers had a 43 percent complication rate, with viable flaps lifting off radiated wound beds. Only myocutaneous flaps for breast reconstruction and omental flaps with skin grafts and Marlex mesh had no complications. The deeper tissue penetration of modern radiotherapy techniques may make skin grafts and flaps less useful. In reconstruction of radiation ulcers, omental flaps and myocutaneous flaps are especially useful, particularly if the radiation damage can be fully excised. The pull of gravity appears detrimental to myocutaneous flap healing and, if possible, should be avoided by flap design.
mesh_terms: D001940:Breast / Q000601:surgery; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D012086:Reoperation; D012867:Skin / Q000503:physiopathology / Q000528:radiation effects*; D016038:Skin Transplantation; D012883:Skin Ulcer / Q000209:etiology / Q000601:surgery*; D013524:Surgical Flaps; D014945:Wound Healing / Q000528:radiation effects