[Treatment with captopril of idiopathic edemas (author's transl)].
The angiotensin-converting enzyme inhibitor captopril (SQ 14225, 50 mg tid) was used for treating a patient with idiopathic edema. A marked improvement of clinical condition was achieved as confirmed by the significant decrease in the morning-evening weight difference during treatment. No disturbance of arterial pressure regulation as well as side effects were observed after a 22 month-period of treatment. This observation which needs further studies brings a new approach of the treatment of patients with idiopathic edema.
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002216:Captopril / Q000627:therapeutic use*; D004487:Edema / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007866:Leg; D009318:Natriuresis / Q000187:drug effects; D011392:Proline / Q000031:analogs & derivatives*; D012083:Renin / Q000097:blood
D000450:Aldosterone; D011392:Proline; D002216:Captopril; D012083:Renin
Traitement des oedèmes idiopathiques par le captopril. Une observation.