[Neuropharmacological regulation of pituitary hormones. Role of acetylcholine, gamma-aminobutyric acid, histamine and endorphins (author's transl)].
The secretion of pituitary hormones is controlled by hypothalamic hormones which are synthetized by neurosecreting cells whose activity is modulated by different neurotransmitters as dopamine and serotonin. Centrally acting drugs interfere with the activity of these neurotransmitters. Thus they may influence the secretion of pituitary hormones. Acetylcholine, gamma-aminobutyric acid, histamine and endorphins seem also to influence the pituitary secretion. The endocrine effects of drugs (opiates, antiparkinson, antiepileptic, and antihistaminic agents) acting on these neurotransmitters is reviewed.
D000109:Acetylcholine / Q000502:physiology*; D000818:Animals; D004723:Endorphins / Q000502:physiology*; D006632:Histamine / Q000502:physiology*; D006801:Humans; D010902:Pituitary Gland / Q000187:drug effects; D010907:Pituitary Hormones / Q000378:metabolism*; D051381:Rats; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D004723:Endorphins; D010907:Pituitary Hormones; D005680:gamma-Aminobutyric Acid; D006632:Histamine; D000109:Acetylcholine
Régulation neuropharmacologique des hormones hypophysaires. Rôle de l'acétycholine, du GABA, de l'histamine et des endorphines.