title: [Transplantation of pancreas and kidney in diabetic nephropathy (author's transl)].
abstract: In juvenile diabetics with diabetic nephropathy transplantation of the pancreas at the time of renal transplantation is thought to improve the progression of diabetic complications. Between 1. 7. 1980 and 31. 12. 1981, nine kidney and pancreas transplants were performed for this reason. Five pancreas transplantations failed for non-immunological causes. Of four successful transplantations, two transplants were later rejected through non-reversible immunological cause. The function of both organs has remained normal in two patients after 18 and 9 months, respectively. These patients are normoglycaemic on a normal diet and, despite prednisone medication, do not require insulin administration.
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D003928:Diabetic Nephropathies / Q000601:surgery*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008722:Methods; D008875:Middle Aged; D016035:Pancreas Transplantation; D011241:Prednisone / Q000627:therapeutic use; D014184:Transplantation, Homologous
chemical_list: D001379:Azathioprine; D011241:Prednisone
vernacular_title: Pankreas- und Nierentransplantation bei diabetischer Nephropathie.