The effects of vitamin A toxicity on calcium and lipid metabolism in chronic renal failure.
Serum vitamin A levels were high in haemodialysis patients, and were found to correlate with plasma calcium, triglyceride, cholesterol and insulin levels. Vitamin A containing multivitamin supplements were found to contribute to increased serum vitamin A levels, and their withdrawal in seven patients caused a significant decrease in serum vitamin A and calcium levels, with no effect on lipid levels. Vitamin A containing preparations should therefore be prescribed with caution in these patients.
D000328:Adult; D002118:Calcium / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced; D007328:Insulin / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood*; D008055:Lipids / Q000097:blood*; D014280:Triglycerides / Q000097:blood; D014801:Vitamin A / Q000009:adverse effects* / Q000097:blood
D007328:Insulin; D008055:Lipids; D014280:Triglycerides; D014801:Vitamin A; D002784:Cholesterol; D002118:Calcium