[Sensitivity in vitro of some bacterial strains to procaine].
The action range of procaine, this multipotent substance, may also be extended to the domain of bacteriology due to its bacteriostatic, bactericide, fungistatic and fungicide properties. The antibacterial activity of Höechst procaine hydrochlorate powder was determined on 15 bacterial strains and 2 Candida strains isolated from various human infections. The in vitro antibacterial effect of the powder was demonstrated by the diffusimetric and the dilution methods, determining the minimal inhibitory concentration and minimal bactericide concentration. Procaine had a high antibacterial activity against Streptococcus B hemolyticus gr. A and viridans, and against certain enterobacteria (E. coli Proteus). THe results show the possibility of using procaine also in the local treatment of infections caused by these agents.
D001419:Bacteria / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011343:Procaine / Q000494:pharmacology*
D011343:Procaine
Sensibilitatea in vitro a unor tulpini bacteriene faţă de procaină.