[Urokinase (in situ) in the case of acute ischemia of the lower limbs (author's transl)].
Eighteen patients with severe, acute ischemia of the lower limbs were treated with an arterial perfusion of the ischemic leg with Urokinase. This was associated, in thirteen patients, with a limited attempt of revascularization. The result of this treatment was an immediate improvement in twelve cases, which lasted, more than six months, in six patients. The authors insist on the interest of the arteriography performed after the fibrinolytic treatment in order to complete the revascularization.
D000208:Acute Disease; D000368:Aged; D000792:Angiography; D010450:Endopeptidases / Q000627:therapeutic use*; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D007511:Ischemia / Q000188:drug therapy* / Q000601:surgery; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*
D010450:Endopeptidases; D014568:Urokinase-Type Plasminogen Activator
L'urokinase in situ dans l'ischémie aiguë des membres inférieurs.