IgA nephropathy associated with myasthenia gravis and scleritis.
A 29-year-old male patient with IgA nephropathy developed scleritis and myasthenia gravis during the follow-up period. No lymphocytic infiltration or atrophy in muscle fibers was observed in muscle biopsy specimens. However, an immunofluorescent study on the same specimens showed deposits of immunoglobulin A in muscular vessels. The development of scleritis and myasthenia gravis in a patient with IgA nephropathy suggests a common immunologic basis for these disorders.
D000328:Adult; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A; D007249:Inflammation; D008297:Male; D009132:Muscles / Q000473:pathology; D009157:Myasthenia Gravis / Q000150:complications*; D012590:Sclera
D007070:Immunoglobulin A