[The results of 5 years of ancillary chemotherapy of carcinoma of the breast (author's transl)].
484 women were operated between July 1, 1975 and December 31, 1978 for carcinoma of the breast. At least 18 months of follow-up was available until July 1, 1980. 273 patients were observed. 151 women had ancillary chemotherapy with cyclophosphamide, methotrexate, vinblastinsulphate and fluoro-uracil for six cycles. In an additional 60 patients chemotherapy was interrupted for post-operative radiotherapy after three cycles. The premenopausal patients were most helped by ancillary chemotherapy. This was not explained by more frequent mistakes in the treatment of post-menopausal patients. The post-operative radiotherapy did not bring a discernible additional advantage to ancillary chemotherapy. The best results were obtained in women who had no regional metastases in the lymph nodes independent on the size of the primary tumour.
D001943:Breast Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D002986:Clinical Trials as Topic; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008593:Menopause; D008727:Methotrexate / Q000627:therapeutic use; D011182:Postoperative Care; D014747:Vinblastine / Q000627:therapeutic use
D014747:Vinblastine; D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate
Fünf Jahre adjuvante Chemotherapie beim Mammakarzinom.