title: Synthesis and pharmacological activity of derivatives of exo-trimethylenenorbornane, IV.
abstract: The syntheses of (+/-)-1-(exo-5,6-trimethylenenorbornan--2-yl)2-propanamine (IV) starting from (exo-5-trimethylenenobornan-2-yl)acetic acid (I) or (exo-5,6-trimethylenenorbornan-2-yl)acetonitrile (II), as well as a series of amides (V) described. None of compounds (IV) and (V) showed amphetamine-like activity in mice.
mesh_terms: D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009636:Norbornanes / Q000138:chemical synthesis* / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000138:chemical synthesis*
chemical_list: D009636:Norbornanes; D011619:Psychotropic Drugs; D000661:Amphetamine