Vasomotor dynamics associated with cardiac operations. II. Effect of cardiopulmonary bypass on venous tone.
The effect of cardiopulmonary bypass on venous tone was evaluated in 19 patients undergoing coronary artery bypass graft operations. The use of cardiopulmonary bypass with reduction of mean arterial pressure, nonpulsatile blood flow, and emptying of the heart maximally stimulates the sympathoadrenal system and would be expected to cause intense venous constriction. Venous capacitance, however, was reduced by the general effects of the operation, including anesthesia and surgical trauma, while cardiopulmonary bypass was a minor factor in the venous constriction response.
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002302:Cardiac Output; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D003327:Coronary Disease / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D014661:Vasoconstriction