title: [The effect of hemoperfusion with XAD-4 resin on biological constituents of the blood].
abstract: 13 patients who had undergone a haemoperfusion therapy with Amberlite XAD-4 resin (Haemoresin, Braun, F.R.G.) because of acute intoxication were examined for adsorption of biological material from the blood. Treatment lasting on average 4 hours at a blood-circulation rate of 200 ml/min resulted in a 43% reduction of thrombocytes and in changes in the concentrations of proteins, complement factors, triglycerides, aldosterone and testosterone. Low-molecular substances and electrolytes were however, except for sodium, only slightly influenced. Thus this haemoperfusion system is only suitable for shortterm application and cannot be used without substitution for chronic treatment of terminal renal insufficiency.
mesh_terms: D000293:Adolescent; D000327:Adsorption; D000328:Adult; D000368:Aged; D001769:Blood; D001773:Blood Cells / Q000187:drug effects; D001774:Blood Chemical Analysis; D001798:Blood Proteins / Q000032:analysis; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007475:Ion Exchange Resins / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000628:therapy; D011137:Polystyrenes / Q000494:pharmacology*; D011145:Polyvinyls / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D001798:Blood Proteins; D007475:Ion Exchange Resins; D011137:Polystyrenes; D011145:Polyvinyls; C012101:XAD-4 resin
vernacular_title: Einfluss der Hämoperfusion mit XAD-4 Resin auf biologische Bestandteile des Blutes.