title: Plasma levels of 8-methoxypsoralen in psoriatic patients receiving topical 8-methoxypsoralen.
abstract: Using a high-pressure liquid chromatographic technique, plasma psoralen levels have been measured in patients receiving total-body topical photochemotherapy (PUVA). Levels comparable with those found during oral 8-MOP) treatment were observed, suggesting that topical therapy has no advantage over the oral route as far as the hazards of systemic therapy are concerned.
mesh_terms: D000287:Administration, Topical; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D008297:Male; D008730:Methoxsalen / Q000008:administration & dosage / Q000097:blood*; D011701:PUVA Therapy; D010778:Photochemotherapy; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*
chemical_list: D008730:Methoxsalen