Effect of 11-oxahomofolate and its reduced derivatives on human dihydrofolate reductase and on human cells having different amounts of dihydrofolate reductase.
D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008727:Methotrexate / Q000494:pharmacology; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*
C100117:homofolic acid; C023461:11-oxahomofolic acid; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate