title: [Hematological toxicity of ticlopidine? (author's transl)].
abstract: Four cases of bone marrow aplasia, with temporary agranulocytosis (one of them fatal) are described in patients treated with Ticlopidine, an anti-aggregating drug prescribed for prevention of thromboembolic disease. These data suggest that a systematic hematological assessment would be required in the first three months after initiation of Ticlopidine therapy.
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000139:chemically induced*; D010974:Platelet Aggregation / Q000187:drug effects*; D013876:Thiophenes / Q000009:adverse effects*; D013988:Ticlopidine
chemical_list: D013876:Thiophenes; D013988:Ticlopidine
vernacular_title: Toxicité hématologique de la ticlopidine?