Noonan syndrome. A report of male-to-male transmission.
A report of three generations of Noonan syndrome, affecting one female and two males, is described. This is the ninth family in which male-to-male transmission has been reported, suggesting an autosomal dominant trait.
D000293:Adolescent; D000368:Aged; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005260:Female; D006330:Heart Defects, Congenital / Q000235:genetics; D006801:Humans; D008297:Male; D009634:Noonan Syndrome / Q000235:genetics*; D010375:Pedigree