title: [Thrombotic obstruction with tilting disc valves (author's transl)].
abstract: Valve thromboses were observed in nine patients, seven females and two males, aged 46 years on average, between 1/2 and 5 1/2 years after replacement of a mitral valve (n = 6) or an aortic valve (n = 3) by a tilting disc valve (Björk-Shiley, n = 6; Lillehei-Kaster n = 3). In eight cases reoperation was necessary, mainly as an emergency. One patient died preoperatively, five died intra- or postoperatively. Besides the adequate valve type, prophylaxis of valve thrombosis by conscientious anticoagulation is the most important measure. Should leading symptoms - disappearance of valve click and increasing cardiac insufficiency during irregular anticoagulation - occur, immediate referral to cardiac surgery is required.
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001021:Aortic Valve; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D011183:Postoperative Complications; D013927:Thrombosis / Q000209:etiology* / Q000517:prevention & control; D013997:Time Factors
chemical_list: D000925:Anticoagulants
vernacular_title: Thrombotische Obstruktion von Kippscheibenklappen. Diagnostik und Therapie.