Recurrence rate of ABO hemolytic disease of the newborn.
ABO hemolytic disease of the newborn is a common and potentially severe disease. It can cause hyperbilirubinemia and anemia in the infant. A review of 230 primigravid mothers of affected offspring is presented. Evaluation of their subsequent pregnancies showed a recurrence rate of 88% in those infants at risk for the disease (of same blood type as their index sibling), with 62% of the affected infants requiring therapy. Guidelines for antenatal counseling are presented.
D000017:ABO Blood-Group System; D001663:Bilirubin / Q000097:blood; D001788:Blood Grouping and Crossmatching; D003298:Coombs Test; D004899:Erythroblastosis, Fetal / Q000097:blood* / Q000628:therapy; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D010789:Phototherapy; D011247:Pregnancy; D012008:Recurrence
D000017:ABO Blood-Group System; D001663:Bilirubin