Genome size and DNA complexity of Plasmodium falciparum.
Plasmodium falciparum DNA was prepared from cells cultured in vitro in human erythrocytes. The P. falciparum DNA was mixed with a tritium-labeled Escherichia coli DNA standard, and the kinetics of reassociation were measured using hydroxyapatite chromatography. It was found that the P. falciparum genome size is equal to 3.8 . 10(8) nucleotide pairs, and that a repetitive component is present which contains about 10% of the DNA. The average repetition frequency in this component is 95 copies of each sequence.
D000818:Animals; D004247:DNA / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D004912:Erythrocytes; D004926:Escherichia coli; D005796:Genes; D006801:Humans; D007700:Kinetics; D009695:Nucleic Acid Renaturation; D010963:Plasmodium falciparum / Q000032:analysis*; D013045:Species Specificity
D004269:DNA, Bacterial; D004247:DNA