title: Retinoids, urinary bladder carcinogenesis, and chemoprevention: a review and synthesis.
abstract: An analysis of the effects of natural (vitamin A) and synthetic retinoids on experimental carcinogenesis of the urinary bladder indicates that inhibitory activity is carcinogen- or carcinogen-class-specific. These findings suggest that there may be more than one pathway for the neo-differentiation of urothelial cells to frank carcinoma and that these pathways may be related to both carcinogen class and dietary vitamin A status.
mesh_terms: D002471:Cell Transformation, Neoplastic; D006801:Humans; D009154:Mutation; D001749:Urinary Bladder Neoplasms / Q000209:etiology* / Q000517:prevention & control; D014801:Vitamin A / Q000494:pharmacology*; D014802:Vitamin A Deficiency / Q000150:complications
chemical_list: D014801:Vitamin A