Treatment of acute uncomplicated urinary tract infections by cephalexin, with special reference to the antibody-coated bacteria.
In 68 college-age females with acute uncomplicated urinary tract infections (UTI), ACB testing revealed that 36.8% of the infections were localized in the kidney and 63.2% in the urinary bladder. Sixty-two patients who completed 10 days of therapy with cephalexin showed a clinical and bacteriologic cure on the last day of therapy. Ninety-seven percent of patients were free of UTI at 1 week post therapy. Cephalexin appeared to be equally effective in treatment of both ACB-positive and ACB-negative infections. Antibody-coated bacteria did not correlate with symptoms, response to therapy, or rate of recurrences.
D000328:Adult; D000919:Antibody-Coated Bacteria Test, Urinary; D002506:Cephalexin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000276:immunology / Q000382:microbiology
D002506:Cephalexin