title: Use of subcutaneous deferoxamine in a child with hemochromatosis associated with congenital dyserythropoietic anemia, type I.
abstract: A 12-year-old girl with congenital dyserythropoietic anemia, type I, was diagnosed as having hemochromatosis. Deferoxamine was given subcutaneously for 14 months. Iron overload, as measured by liver iron and serum ferritin levels, was reduced substantially, liver function tests improved, and hepatomegaly decreased. Toxicity was negligible.
mesh_terms: D000742:Anemia, Dyserythropoietic, Congenital / Q000150:complications*; D000745:Anemia, Hemolytic, Congenital / Q000150:complications*; D001706:Biopsy; D002648:Child; D003676:Deferoxamine / Q000008:administration & dosage*; D005260:Female; D005293:Ferritins / Q000032:analysis; D006432:Hemochromatosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007263:Infusions, Parenteral; D008099:Liver / Q000032:analysis / Q000473:pathology
chemical_list: D005293:Ferritins; D003676:Deferoxamine