Activity of alkaline phosphatase in the serum of normal and ascorbic-acid-deficient guinea pigs.
Guinea pigs well supplied with vitamin C show a linear relation between serum alkaline phosphatase activity and body weight. Investigations in guinea pigs induced to low ascorbic-acid levels by two different procedures (complete and partial deprivation of vitamin C) demonstrated that the activity of the alkaline phosphatase is not generally decreased in the serum of ascorbic-acid-deficient guinea pigs. Decreases of the serum enzyme levels reported in guinea pigs completely deprived of vitamin C, i.e. in acute deficiency, may be due to stress factors.
D000375:Aging; D000469:Alkaline Phosphatase / Q000097:blood*; D000818:Animals; D001206:Ascorbic Acid Deficiency / Q000201:enzymology*; D001835:Body Weight; D006168:Guinea Pigs / Q000378:metabolism*
D000469:Alkaline Phosphatase