Nodular regenerative hyperplasia of the liver in a patient with diabetes mellitus.
Diffuse nodular regenerative hyperplasia of the liver (NRH) is a rare cause of portal hypertension. It is characterized by diffuse nodularity of the liver without cirrhosis. NRH is usually associated with other diseases, most commonly Felty's syndrome. A case is reported in which maturity-onset diabetes mellitus was accompanied by elevated serum insulin levels. Hepatotrophic hormones such as insulin or glucagon may play a role in the development of some cases of NRH.
D001706:Biopsy; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000209:etiology*; D008875:Middle Aged