title: [Morphohistochemical characteristics of tympanosclerosis and problems in its morphogenesis].
abstract: The results of morphological and histochemical examinations of tympanosclerosis performed on the operation materials from 64 patients suffering from conductive hypoacusis are presented. The structure of the tympanosclerotic plaque was shown to reflect the combination of degenerative and fibroplastic alterations of mucoperiosteum with the outcome into petrification and hyalinosis. The location, structure, and histochemical features of the tympanosclerotic plaque prevent considering it to be a derivative of the granulation tissue. At the same time there are reasons to assume the serous nature of the preceeding mucoperiosteum inflammation. The development of tympanosclerosis reflects the reactive features of mucoperiosteum as the bradytrophic tissue possessing osteogenic potentials.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004427:Ear Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D004432:Ear, Middle / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D014432:Tympanic Membrane / Q000378:metabolism / Q000473:pathology
vernacular_title: Morfogistokhimicheskaia kharakteristika timpanoskleroza i nekotorye voprosy ego morfogeneza.