Energy metabolism in the erythrocytes of thoroughbred horses connected with perinatal physiological hemolysis.
1. The metabolism in the erythrocytes of thoroughbred horses in a sequential study from umbilical cord to the 1st month was investigated. 2. Emphasis was put on hemolytic period at which: (a). PFK, GSH-Px and GSH play a significant role. (b). There is a lower glucose consumption determined by a decreased activity in several enzymatic steps. (c). Singularly high concentrations of 2-3DPG and ATP were detected. 3. It has been suggested that the metabolic adjustments were achieved by an increased activity of the hexose monophosphate shunt, G-3PD and AK.
D000818:Animals; D000831:Animals, Newborn; D004734:Energy Metabolism; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005978:Glutathione / Q000097:blood; D006019:Glycolysis; D006461:Hemolysis; D006736:Horses / Q000097:blood*; D008297:Male
D005978:Glutathione