Metabolic depletion of erythrocytes is accompanied by a decrease of sialic acid during blood bank storage: a reply.
Erythrocytes lose about 10% of their sialic acid during banking in ACD-AG medium. In contrast to these findings, Pessina et al. could not detect a significant banking-related sialic acid decrease. The present paper explains this discrepancy. The vesiculation of erythrocytes is mainly responsible for the observed sialic acid loss during blood preservation.
D001793:Blood Preservation; D004905:Erythrocyte Aging; D004910:Erythrocyte Membrane / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism* / Q000502:physiology; D006801:Humans; D010743:Phospholipids / Q000097:blood; D012794:Sialic Acids / Q000097:blood*; D013997:Time Factors
D010743:Phospholipids; D012794:Sialic Acids