Pulmonary candidiasis complicating a severe burn treated with miconazole.
A 33/4-year-old boy received a 50 per cent body surface area burn in a house fire. On the eighteenth day post burn he was moribund and a diagnosis of pulmonary candidiasis was made following tracheal cultures and X-ray changes after a period of progressive deterioration during which he had received multiple antibiotics and assisted ventilation. Treatment of this pulmonary candidiasis was with intravenous miconazole. The child's clinical condition rapidly improved over the following 24-48 hours and the X-ray changes resolved. He was subsequently discharged fully healed.
D002056:Burns / Q000150:complications*; D002177:Candidiasis / Q000188:drug therapy* / Q000209:etiology; D002675:Child, Preschool; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008172:Lung Diseases, Fungal / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008825:Miconazole / Q000627:therapeutic use*
D007093:Imidazoles; D008825:Miconazole