Preparation and ESCA characterization of poly(vinyl chloride) surface-grafted with heparin-complexing poly(amido amine) chains.
By a simple process poly(amido-amine) chains have been grafted on the surface of poly(vinyl chloride). Grafted poly(vinyl chloride) is able to adsorb heparin, thus providing potentially non-thrombogenic surfaces. The grafting of poly(amido-amine), and the heparin adsorption have been studied by ESCA. It has been found that the total amount of grafted poly(amido-amine) depends on the molecular weight of the poly(amido-amine) used in the grafting reaction, but the amount of heparin adsorbed on the grafted material is relatively independent of the length of the poly(amino-amine) grafted chains.
D006493:Heparin; D009757:Nylons; D011108:Polymers; D011143:Polyvinyl Chloride; D011145:Polyvinyls; D013057:Spectrum Analysis; D013499:Surface Properties
D009757:Nylons; D011108:Polymers; D011145:Polyvinyls; D011143:Polyvinyl Chloride; D006493:Heparin