Thyrotoxicosis and dyspnoea.
Shortness of breath is a common symptom in thyrotoxicosis and it may have a number of causes. We have studied dyspnoea, skeletal muscle power and respiratory muscle power in eleven patients who had thyrotoxicosis with no evidence of heart failure. Four patients (36.4%) had a marked improvement with treatment in the maximal inspiratory pressure developed at the mouth. All four were breathless and had a proximal myopathy before treatment. This confirms the existence of a group of thyrotoxic patients with a reversible respiratory muscle myopathy which may explain the frequent finding of breathlessness on exertion in such patients.
D000328:Adult; D000368:Aged; D002231:Carbimazole / Q000627:therapeutic use; D004417:Dyspnea / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology*; D012129:Respiratory Function Tests; D013960:Thyroid Function Tests
D002231:Carbimazole