title: In vivo and in vitro studies on the binding nature of terreic acid with macromolecules such as protein and nucleic acids.
abstract: The binding of terreic acid to macromolecules such as nucleic acids and protein was examined. In vivo studies using [14C]terreic acid showed that radioactivity was incorporated into the protein and nucleic acid fractions of the liver mice. In vitro experiments with human serum showed that [14C]terreic acid bound to the albumin component and spectral studies indicated that terreic acid also combined with hepatic DNA.
mesh_terms: D000818:Animals; D005260:Female; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D009183:Mycotoxins / Q000378:metabolism*; D009696:Nucleic Acids / Q000378:metabolism*; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism*; D011809:Quinones / Q000378:metabolism
chemical_list: D009183:Mycotoxins; D009696:Nucleic Acids; D011506:Proteins; D011809:Quinones; C009400:terreic acid