title: VIP (vasoactive intestinal polypeptide)--immunoreactive innervation of the portal vein.
abstract: Nerve fibres displaying immunoreactivity for vasoactive intestinal polypeptide (VIP) were found in the wall of the portal vein in cats, guinea pigs, rats and mice. In whole-mount preparations a sparse network of VIP fibres was seen in the vessel wall. Electrical field stimulation of the rat portal vein in vitro caused a significant release of VIP. The results suggest that VIP ergic nerve fibres play a role in the regulation of portal blood flow.
mesh_terms: D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005768:Gastrointestinal Hormones / Q000378:metabolism*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009474:Neurons / Q000378:metabolism*; D011169:Portal Vein / Q000294:innervation*; D051381:Rats; D013045:Species Specificity; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*; D014664:Vasodilation
chemical_list: D005768:Gastrointestinal Hormones; D014660:Vasoactive Intestinal Peptide