Multiple cutaneous focal mucinoses with hypothyroidism.
A 54-year-old woman with myxedema had hundreds of discrete cutaneous mucinous papules, which responded dramatically to appropriate replacement therapy with L-thyroxine. Each lesion both clinically and histologically resembled a cutaneous focal mucinosis (cutaneous myxoma). Multiple cutaneous focal mucinoses are a previously undescribed manifestation of hypothyroidism that can be differentiated from other syndromes that have cutaneous mucinous deposits.
D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D009077:Mucins / Q000032:analysis; D009230:Myxedema / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000032:analysis; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology; D013974:Thyroxine / Q000627:therapeutic use
D009077:Mucins; D013974:Thyroxine