[Role of membrane structure in the formation of the myofibrillar system in myogenesis].
The leading role of membranes in the formation of the myofibrillar system at different stages of chick embryo development (on the 8th, 12th, 15th day) was considered. At the early stages the myofibrillar assembly depends mainly on the plasma membrane (myofibrils are located beneath the sarcolemma) and later on it depends on the developing sarcoplasmic reticulum and T-system. It was shown that transverse tubules invaginating from the plasma membrane are the framework for the forming myofibrillar system, and thin filaments are attached to the transverse tubules at the sites of future Z-lines. These results support the idea that Z-lines originate from the membrane. Destruction of the membrane elements provokes disorganization of myofibrillar contractile material.
D000818:Animals; D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D002642:Chick Embryo; D008854:Microscopy, Electron; D009132:Muscles / Q000196:embryology* / Q000648:ultrastructure; D009210:Myofibrils / Q000502:physiology* / Q000648:ultrastructure; D012519:Sarcoplasmic Reticulum / Q000502:physiology
O roli membrannykh struktur v formirovanii miofibrilliarnogo apparata v miogeneze.