BCG-induced inhibition and destruction of Taenia taeniaeformis in mice.
Pretreatment of mice with BCG induced a high level of protection against infection with Taenia taeniaeformis. Protection was manifested both during and after establishment by the parasite suggesting that two separate mechanisms were stimulated by BCG. The first inhibits initial establishment by the parasite and may be antibody mediated. The second is responsible for the destruction of developing strobilocerci in the liver and may require the involvement of cellular defence mechanisms.
D000818:Animals; D001500:BCG Vaccine / Q000494:pharmacology*; D006099:Granuloma / Q000473:pathology; D008099:Liver / Q000469:parasitology / Q000473:pathology; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D013154:Spleen / Q000276:immunology; D013621:Taenia / Q000254:growth & development; D013622:Taeniasis / Q000276:immunology* / Q000473:pathology
D001500:BCG Vaccine