Halothane hepatitis in a young child.
A 4-year-old girl developed severe hepatitis following the fourth administration of halothane in a period of 5 months. She was shown to have a circulating antibody which acted specifically against rabbit hepatocyte previously sensitized to halothane. The patient made a full recovery from the hepatitis, but 5 months later, developed diabetes mellitus.
D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D000906:Antibodies / Q000032:analysis; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000276:immunology; D002675:Child, Preschool; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D006801:Humans
D000906:Antibodies; D006221:Halothane