The influence of spermidine (polyamines) on DNA depurination in vitro.
The influence of the spermidine, spermine and putrescine on the DNA depurination rate was studied. These polyamines protect DNA against depurination. The rate of Col EI DNA depurination at pH 4.3 was decreased over 10-fold by addition of 10 mM polyamines.
D004269:DNA, Bacterial / Q000378:metabolism*; D004926:Escherichia coli; D007700:Kinetics; D010957:Plasmids; D011700:Putrescine / Q000494:pharmacology*; D013095:Spermidine / Q000494:pharmacology*; D013096:Spermine / Q000494:pharmacology*
D004269:DNA, Bacterial; D013096:Spermine; D013095:Spermidine; D011700:Putrescine