Platelet activation by non-coagulant snake venom components.
Platelet activation by non-coagulant components of snake venoms is reviewed, with particular emphasis on the effects of convulxin. The latter is present in the venom of Crotalus durissus cascavella, and induces ADP and thromboxane - independent platelet aggregation. Convulxin and similar proteins are tools for the study of platelet functions.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000371:Agglutination; D000818:Animals; D001792:Blood Platelets / Q000502:physiology; D003435:Crotalid Venoms / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects*; D012910:Snake Venoms / Q000494:pharmacology*; D013045:Species Specificity; D013931:Thromboxanes / Q000494:pharmacology
D003435:Crotalid Venoms; D012910:Snake Venoms; D013931:Thromboxanes; D000244:Adenosine Diphosphate; D007213:Indomethacin