Coffee consumption during pregnancy: subsequent behavioral abnormalities of the offspring.
Offspring of rats fed coffee during pregnancy had reduced body, liver, and brain weight at birth. By 30 days postnatally these animals had recovered in size but exhibited increased locomotion, decreased grooming time, and decreased time spent with a novel object. Offspring of dams fed decaffeinated coffee demonstrated reduced liver weight at birth and similar behavioral characteristics at 30 days of age.
D000818:Animals; D000831:Animals, Newborn; D001522:Behavior, Animal / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002110:Caffeine / Q000633:toxicity*; D003069:Coffee / Q000633:toxicity*; D005260:Female; D005333:Fetus / Q000187:drug effects; D008297:Male; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains
D003069:Coffee; D002110:Caffeine