title: Free jejunal mucosal patch graft reconstruction of the oropharynx.
abstract: We used microvascular anastomoses to transpose free pedicle jejunal mucosal patch grafts in seven patients. The procedure has been particularly helpful in rebuilding large intra-oral mucosal defects created by extensive resections for advanced carcinomas. Some of the benefits of this technique have included a one-stage procedure, which requires two to three weeks for healing; abundant donor tissue with characteristics similar to oral mucosa; near-normal facial appearance; and preservation of maximum tongue function. An unexpected benefit has been relief of annoying xerostomia by the jejunal mucous secretion. The most severe complication, which resulted in one death, was the excessive oral jejunal mucous secretion in the early postoperative period. It led to significant aspiration pneumonitis. To prevent this problem, we recommend a routine tracheostomy combined with rigorous pulmonary care whenever a jejunal patch graft is used.
mesh_terms: D000368:Aged; D006085:Graft Survival; D006257:Head / Q000601:surgery; D006801:Humans; D007413:Intestinal Mucosa / Q000098:blood supply / Q000637:transplantation*; D007583:Jejunum / Q000098:blood supply / Q000637:transplantation*; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000601:surgery; D009960:Oropharynx / Q000601:surgery*; D014140:Tracheotomy; D014656:Vascular Surgical Procedures