Cerebrospinal fluid IgE and the diagnosis of cerebral cysticercosis.
Cerebral cysticercosis (CC) is a common cause of seizures and other central nervous system disorders in the Mexican-American population. The elevation of serum IgE in many parasitic diseases led us to study CSF and serum IgE in patients with CC diagnosed by pathologic, radiologic or clinical criteria. A paper disc radioimmunoassay, sensitive to 0.01 IU/ml, was used to measure CSF and serum IgE in 69 patients. The mean CSF IgE level in Mexicans with CC was 0.44 IU/ml compared to 0.28 IU/ml in Mexicans without CC and 0.07 IU/ml in non-Mexicans without CC.
D001927:Brain Diseases / Q000175:diagnosis* / Q000276:immunology; D003551:Cysticercosis / Q000175:diagnosis* / Q000276:immunology; D006630:Hispanic or Latino; D006801:Humans; D007073:Immunoglobulin E / Q000134:cerebrospinal fluid*; D011864:Radioimmunosorbent Test / Q000379:methods
D007073:Immunoglobulin E