An unusual pontine mass lesion.
A 27-year-old Puerto Rican man presented to Yale-New Haven Hospital with a six-week history of left-sided headache, diplopia, and drooping of the left side of his face. Cerebrospinal fluid examination showed a lymphocytic pleocytosis and a CT scan of the brain revealed an unusual intrapontine mass lesion requiring systemic antifungal therapy. This case emphasizes many of the diagnostic and therapeutic considerations required for effective therapy of fungal disease in the central nervous system.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000792:Angiography; D001921:Brain / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000473:pathology*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002555:Cerebrospinal Fluid / Q000382:microbiology; D003453:Cryptococcosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D003937:Diagnosis, Differential; D004357:Drug Synergism; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011149:Pons / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D000666:Amphotericin B; D005437:Flucytosine