[Prostacyclin versus regional heparinisation during haemodialysis (author's transl)].
Ten patients with terminal renal failure underwent two haemodialysis sessions: one with regional heparinisation, the other with prostacyclin (PGI2). The values compared included duration of dialysis, amount of fluid perfused, weight loss, coagulation in the dialyser, side-effects, changes in electrolyte, urea, creatinine and blood gases values and changes in blood count and differential platelet function was included in coagulation studies. The only statistically significant differences recorded concerned weight loss during dialysis (inferior with PGI2) and number of leucocytes after dialysis (superior with PGI2).
D001777:Blood Coagulation / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D011464:Epoprostenol / Q000008:administration & dosage* / Q000009:adverse effects; D006493:Heparin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D007958:Leukocyte Count; D010974:Platelet Aggregation / Q000187:drug effects; D011453:Prostaglandins / Q000008:administration & dosage*; D006435:Renal Dialysis / Q000379:methods*
D011453:Prostaglandins; D006493:Heparin; D011464:Epoprostenol
Comparaison de la prostacycline et de l'heparinisation régionale au cours de la séance d'hémodialyse.