Two different modes of membrane damaging action by bacterial thiol-activated haemolysins.
The mode of action to cause membrane damage to human diploid fibroblasts by streptolysin 0 is not typical for that of all thiol-activated cytolysins. Theta-toxin and alveolysin, on the other hand, share all properties investigated and may thus, with regard to mechanisms of membrane damaging action, constitute a subgroup among thiol-activated haemolysins.
D000327:Adsorption; D001419:Bacteria; D001427:Bacterial Toxins / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects*; D005347:Fibroblasts / Q000187:drug effects / Q000502:physiology; D006460:Hemolysin Proteins / Q000494:pharmacology*; D006801:Humans; D013045:Species Specificity
D001427:Bacterial Toxins; D006460:Hemolysin Proteins