Bronchial secretion concentrations of tobramycin.
The mean concentrations of tobramycin in bronchial secretions from patients with pneumonia were almost two times greater than secretions from patients free of lung infection. Mean tobramycin bronchial secretion to serum concentration ratios also were higher when obtained from infected lungs (0.66 versus  0.17) These data suggest that lung infection enhances the concentrations of tobramycin in bronchial secretions.
D000368:Aged; D000900:Anti-Bacterial Agents / Q000032:analysis*; D001826:Body Fluids / Q000032:analysis; D001980:Bronchi / Q000378:metabolism*; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000378:metabolism; D012016:Reference Values; D014031:Tobramycin / Q000032:analysis* / Q000097:blood
D000900:Anti-Bacterial Agents; D014031:Tobramycin