title: Combination of ketamine and xylazine for effective anaesthesia of juvenile chimpanzees (Pan troglodytes).
abstract: Intramuscular administration of ketamine at 15-20 mg/kg bodyweight provided effective levels of anaesthesia for venipuncture in 23 chimpanzees aged 12-36 months. For procedures such as plasmaphereses or percutaneous needle biopsy requiring longer anaesthetic times, xylazine (1 mg/kg) was given with the ketamine. More than 1600 procedures were performed under anaesthesia on the 23 chimpanzees over a period of 18 months with no mortality. Recovery was smooth and uneventful.
mesh_terms: D000758:Anesthesia / Q000662:veterinary*; D000818:Animals; D004338:Drug Combinations; D007273:Injections, Intramuscular; D007649:Ketamine / Q000008:administration & dosage; D002679:Pan troglodytes / Q000502:physiology*; D013843:Thiazines / Q000008:administration & dosage; D014991:Xylazine / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D013843:Thiazines; D014991:Xylazine; D007649:Ketamine