title: Nitrous oxide decreases motility of human neutrophils in vitro.
abstract: The effect of 80 per cent nitrous oxide on motility of human neutrophils obtained from six volunteers was studied in vitro. In every case, random migration through the pores of 3 micrometer-millipore filter paper, was reduced (mean value 16 per cent). Chemotaxis toward casein also was reduced in every case (mean value 22 per cent). These results contrast with a previous study in which mean rates of migration were found to increase following exposure to 2 per cent halothane.
mesh_terms: D002465:Cell Movement / Q000187:drug effects; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D006221:Halothane / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils / Q000187:drug effects*; D009609:Nitrous Oxide / Q000494:pharmacology*
chemical_list: D009609:Nitrous Oxide; D006221:Halothane