title: Ultrastructural analysis of human penile corpus cavernosum. Its significance in tumescence and detumescence.
abstract: The erectile tissue from 15 normal and impotent male patients was studied by electron microscopy to determine if any ultrastructural features could contribute to the basic understanding of the physiology of penile erection and detumescence. It was found that the endothelium lining the cavernous lacunae contained both contractile elements and Weibel-Palade bodies which have a possible role in vasoconstriction. Within the trabeculae of the cavernous body there was an abundance of elastin as well as oxytalan and elaunin fibers around bundles of smooth muscle. With these elements affording an anchorage system for contraction of smooth muscles within the trabeculae, an alternate contraction of smooth muscles and endothelium could account for the erectile and detumescent states.
mesh_terms: D000328:Adult; D000368:Aged; D003593:Cytoplasm / Q000648:ultrastructure; D004549:Elastin / Q000032:analysis; D004727:Endothelium / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000648:ultrastructure; D009210:Myofibrils / Q000648:ultrastructure; D009940:Organoids / Q000648:ultrastructure; D010413:Penis / Q000502:physiology / Q000648:ultrastructure*
chemical_list: D004549:Elastin