Abscopal effects of local fractionated X-irradiation of face and jaw region.
The abscopal effects of high doses of X-irradiation, 6000 R given in 12 fractions locally on rat face and jaw region, upon the haematopoietic and lymphatic tissues, were studied. Haematological and pathophysiological studies were performed. Peripheral blood samples were taken after the 7th, 17th and 27th day during the course of the irradiation. 24 hours after the last irradiation the smears of femur bone-marrow were done. In the smears, the cells of erythrocyte and leukocyte series, as well as their mitotic index were determined. 24 hours after the irradiation the pieces of lymph nodes and salivary glands were taken for histological analysis. A significant depression of peripheral leukocyte counts was found in all observation intervals as well as the change in mitotic index of granulocyte series in bone marrow. No significant histological changes on the lymph nodes and salivary gland section were found 24 hours after the last irradiation.
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects*; D005145:Face / Q000528:radiation effects; D007568:Jaw / Q000528:radiation effects; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000473:pathology; D008221:Lymphoid Tissue / Q000528:radiation effects*; D011829:Radiation Dosage; D051381:Rats; D012469:Salivary Glands / Q000473:pathology / Q000528:radiation effects; D013997:Time Factors