title: [Restless legs and nocturnal leg spasms--forgotten facts in diagnosis--new facts for therapy].
abstract: An angiologist's experience with the symptom of restless legs is reported. The condition was diagnosed in 103 patients presenting with pain in their legs occurring predominantly at rest and vanishing with walking. Organic lesions could not be identified (in 76%) or were not responsible for the discomfort (in 24%). A depressive state, most often masked, was recognized in 67%. In 42% anxiety was present alone, and in 49% frank depression was diagnosed. In 9% psychiatric treatment was mandatory. Patients with no depression were either not treated (33%) or were given type I-antiarrhythmic drugs (mostly disopyramide) with good results. These drugs were only transiently effective in depressed patients since anxiety was often intensified when the symptom of restless legs disappeared. Antidepressant agents, though ineffective when given alone, were most helpful when administered together with disopyramide.
mesh_terms: D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D001007:Anxiety / Q000150:complications; D003863:Depression / Q000150:complications; D004206:Disopyramide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000175:diagnosis*; D012148:Restless Legs Syndrome / Q000175:diagnosis*
chemical_list: D000889:Anti-Arrhythmia Agents; D000928:Antidepressive Agents; D004206:Disopyramide
vernacular_title: Restless legs und nächtliche Beinkrämpfe - Vergessenes zur Diagnose - Neues zur Therapie.