title: Ovarian development in 46,XY gonadal dysgenesis.
abstract: In humans the XY ovary is degenerative, there being scant evidence of persistence of that organ beyond the perinatal period. Here we describe indications of functional ovarian tissue in a 17-year-old female with male karyotype, H-Y+ cellular phenotype, and some signs of the Turner syndrome. Her gonads were removed after the onset of secondary amenorrhea. Histological examination revealed a degenerative right ovary devoid of germ cells and follicles, and a left streak gonad. There was no trace of testicular development in either side.
mesh_terms: D000293:Adolescent; D005260:Female; D006059:Gonadal Dysgenesis / Q000473:pathology*; D006061:Gonadal Dysgenesis, 46,XY / Q000235:genetics / Q000473:pathology*; D006182:H-Y Antigen / Q000032:analysis; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D008214:Lymphocytes / Q000032:analysis; D010053:Ovary / Q000473:pathology; D010641:Phenotype
chemical_list: D006182:H-Y Antigen; D006680:HLA Antigens