Methyl derivatives of 2-acetamido-2-deoxy-3-O-(beta-D-glucopyranosyluronic acid)-D-glucose (hyalobiouronic acid) from methylated hyaluronic acid.
Methanolysis of methylated hyaluronic acid, followed by acetylation, gave, in 70% yield, crystalline methyl 2-acetamido-2-deoxy-4,6-di-O-methyl-3-O-(methyl 4-O-acetyl-2,3-di-O-methyl-beta-D-glucopyranosyluronate) -alpha-D-glucopyranoside. Removal of the O-acetyl and methyl ester groups gave compounds that are useful in the investigation, by 1H-n.m.r. spectroscopy, of interaction within chains of hyaluronic acid in solution.
D002236:Carbohydrate Conformation; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D011247:Pregnancy; D014470:Umbilical Cord
D006820:Hyaluronic Acid