Interactions between inosine and adenosine: experimental researches.
Experimental investigations have shown that inosine enhances purinergic reactivity. This was examined with adenosine at the level of the cardiovascular, intestinal and uterine musculature. The mechanism of this activity may probably be inhibition of uptake without significantly altering serum adenosinase.
D000241:Adenosine / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D004347:Drug Interactions; D004386:Duodenum / Q000187:drug effects / Q000378:metabolism; D005260:Female; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007288:Inosine / Q000378:metabolism / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009206:Myocardium / Q000378:metabolism; D009699:N-Glycosyl Hydrolases / Q000097:blood; D011898:Ranidae; D051381:Rats; D014599:Uterus / Q000187:drug effects / Q000378:metabolism
D007288:Inosine; D009699:N-Glycosyl Hydrolases; C019599:adenosine nucleosidase; D000241:Adenosine