The effect on blood pressure, ECG and heart rate of psychological stress, static and dynamic muscle work. A study on members of families with known aggregation of essential hypertension.
A total of 195 relatives of patients from families with essential hypertension in at least two generations have been examined in regard to blood pressure (BP) and heart rate (HR) during muscle work and psychological stress. They were compared to controls without heredity for hypertension. The differences in BP and HR at rest between the groups were maintained throughout all tests, but during heavy dynamic muscle work systolic BP rose less in relatives than in controls. When relatives and controls were divided into subgroups, we found that BP was more related to age in relatives than in controls, both at rest and during the provocation tests. The differences in BP between the groups could thus depend on a genetic factor with greater penetration with increasing age.
D000328:Adult; D000367:Age Factors; D001794:Blood Pressure; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D013315:Stress, Psychological / Q000503:physiopathology*