Measles and measles vaccine isolated amerindian tribes. I. The 1971 Trio ((Tiriyo) epidemic.
Measles in an unvaccinated virgin population exacted a death toll of 4.2% which fell particularly hard on the age groups which would ordinarily be protected by maternal antibody. The organ system most affected was quite variable. When the virus spread to a largely vaccinated village it caused only one death. Herd immunity seemed to protect many who were not vaccinated. Vaccine failed to protect 7.7% of the recipients. Some of these failures may have been due to erroneous record, vaccination in the presence of maternal antibody or inactivated vaccine, but most occurred in a few family groups related by genetics and similar past immunological experience.
D000328:Adult; D001938:Brazil; D002648:Child; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007199:Indians, South American; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D008458:Measles Vaccine / Q000276:immunology*; D014611:Vaccination
D008458:Measles Vaccine