Levels of transcobalamins I, II, and III during pregnancy and in cord blood.
The levels of unsaturated serum transcobalamins (TC I, TC II, and TC III) of 193 women at various stages of pregnancy and the puerperium, and of 33 specimens of cord blood, have been measured. In addition, seven subjects were studied serially through pregnancy. The pattern of changes was similar in both groups. TC I and TC III rose steadily during pregnancy and fell in the puerperium, while TC II decreased in the 2nd trimester, rose sharply in the 3rd and fell in the puerperium. The changes in the individual TCs probably result from a complex of hormonally induced changes in binder production, release, or catabolism, and the effect of hydraemia.
D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D049590:Postpartum Period; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D014155:Transcobalamins / Q000032:analysis*; D014805:Vitamin B 12 / Q000097:blood
D001798:Blood Proteins; D014155:Transcobalamins; D014805:Vitamin B 12