title: Should a fixed external reference system be used to analyze left ventricular wall motion?
abstract: To investigate whether a fixed external reference system should be used to most accurately describe regional left ventricular wall motion, we used vectors to analyze a simple model of ventricular contraction. If measured in a fixed external reference system, motion of implanted radiopaque midwall markers may contain translational as well as contractile components. Therefore, comparisons of different reference systems that use marker motion measured in a fixed reference system as a standard will be biased unless proper corrections are included. We conclude that evidence to data does not indicate that the use of a fixed reference system is superior to other methods for analyzing regional ventricular wall motion.
mesh_terms: D006321:Heart / Q000000981:diagnostic imaging; D006331:Heart Diseases / Q000000981:diagnostic imaging; D006352:Heart Ventricles; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D011859:Radiography