[Effect of digitalis on hemodynamics during rest in patients with arterial occlusive diseases, stage II, without cardiac insufficiency].
In 6 patients without clinical symptoms of myocardia insufficiency and with stage II occlusive disease of the femoral artery, blood flow volume at rest, arterial blood pressure and heart rate were measured before, during and for two hours after an iv. infusion of 1.0 mg desacetyl-lanatoside. Blood flow at rest decreased by 23% and peripheral vascular resistance increased by 34%. The increase in the blood pressure amplitude was compensated by a decrease in heart rate. The mechanism of action is discussed. It is concluded that patients suffering from stage II arterial occlusive disease do not benefit at rest from the prophylactic administration of digitalis.
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D001775:Blood Circulation / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D003892:Deslanoside / Q000627:therapeutic use*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007799:Lanatosides / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012146:Rest; D014655:Vascular Resistance / Q000187:drug effects
D007799:Lanatosides; D003892:Deslanoside
Digitaliseffekt auf die Ruhedurchblutung nicht herzinsuffizienter Kranker mit arterieller Verschlusskrankheit Stadium II.