[Effect of aeroions on the relationship between direct and reversed electron transfer in mitochondria under stress].
Opposite changes of direct (respiration) and reversed (from succinate on pyridin nucleotides) energy dependent electron transfer was revealed in rat liver mitochondria under stress. An increase of respiration using added and especially endogenous succinate is observed with corresponding acceleration of phosphorylation. The reversed electron transfer is weaker. This interconversion of the electron flow occurs without the coupling loss and represents a physiological control of the relationship between the external work of mitochondria (ATP synthesis and ion transport) being realized at the expense of direct electron transfer and regenerative synthetic processes with the use of protons supplied by reversed electron transfer. The influence of aeroions on animal after stress resulted in a decrease of the changes described, restricting the excess of direct electron transfer and elevating reductive reactions of reversed electron transfer.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004579:Electron Transport / Q000187:drug effects; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*
D000255:Adenosine Triphosphate
Deĭstvie aéroinov na sootnoshenie priamogo i obratnogo perenosa élektronov v mitokhondriiakh pri stresse.