Cranial blood flow and blood pressure changes during sleep in the human neonate.
The purpose of this study was to evaluate the relation between cranial blood flow (CBF) and arterial blood pressure (BP) in the human newborn. In 29 healthy term neonates simultaneous measurements of CBF using jugular venous occlusion plethysmography and BP using the neonatal Dinamap 847 were performed during active sleep (AS) and quiet sleep (QS) at least 1 h from th end of the last feed. In AS as compared to QS there  was significant rise in CBF (P less than 0.001), mean arterial (P less than 0.001), systolic (P less than 0.001), diastolic (P less than 0.005) and pulse pressure (P less than 0.027). There was a significant correlation between change in the mean arterial pressure (MAP) and change in CBF (r=0.37, P less than 0.05). No correlation, however, was found between changes in CBF and changes in systolic, diastolic or pulse pressures.
D001794:Blood Pressure; D001921:Brain / Q000098:blood supply*; D006801:Humans; D007231:Infant, Newborn; D012890:Sleep / Q000502:physiology*