Phosphorylation inhibits guanine nucleotide exchange on eukaryotic initiation factor 2.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D015852:Eukaryotic Initiation Factor-2; D006153:Guanosine Diphosphate / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism*; D006427:Hemin / Q000378:metabolism; D051379:Mice; D010448:Peptide Initiation Factors / Q000378:metabolism*; D010766:Phosphorylation; D011485:Protein Binding; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D013329:Structure-Activity Relationship; D019892:eIF-2 Kinase
D015852:Eukaryotic Initiation Factor-2; D010448:Peptide Initiation Factors; D006153:Guanosine Diphosphate; D006427:Hemin; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D017346:Protein Serine-Threonine Kinases; D019892:eIF-2 Kinase