Impaired clot retraction in thrombocytopenia due to methyldopa.
We have described a case of thrombocytopenic purpura caused by methyldopa. A methyldopa-dependent antiplatelet antibody as the mechanism of the patient's thrombopenia was suggested by a positive clot retraction inhibition test. This simple in vitro test should be done more often in suspected cases of drug-induced thrombocytopenia.
D003018:Clot Retraction; D005260:Female; D006801:Humans; D008750:Methyldopa / Q000009:adverse effects*; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis
D008750:Methyldopa