Chlorpropamide-induced optic neuropathy.
A 65-year-old woman with adult-onset diabetes treated with chlorpropamide (Diabenese) had a toxic optic neuropathy that resolved with discontinuation of chlorpropamide therapy. Visual loss occurs in diabetics for a variety of reasons, and accurate diagnosis is necessary to institute appropriate therapy. The possibility of a drug-induced optic neuropathy should be considered in the differential diagnosis of visual loss in diabetics.
D000368:Aged; D002747:Chlorpropamide / Q000009:adverse effects*; D003118:Color Perception / Q000187:drug effects; D005260:Female; D006801:Humans; D014786:Vision Disorders / Q000139:chemically induced*; D014792:Visual Acuity / Q000187:drug effects
D002747:Chlorpropamide