Petroleum refinery wastewater induction of the hepatic mixed-function oxidase system in Pacific staghorn sculpin.
Induction of hepatic microsomal cytochrome P450 and aldrin epoxidase was observed in the estuarine sculpin (Leptocottus armatus), following in vivo exposure to Class B petroleum refinery effluent from two West Coast refineries. The data demonstrate the presence and inducibility of the mixed-function oxidase system in Leptocottus armatus. Differences in the extent of mixed-function oxidase induction between the two effluents may be related to differences in wastewater chemistry.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004790:Enzyme Induction; D005399:Fishes / Q000378:metabolism*; D007220:Industrial Waste; D008099:Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000096:biosynthesis*; D010088:Oxidoreductases / Q000096:biosynthesis*; D010578:Petroleum / Q000633:toxicity*
D007220:Industrial Waste; D010578:Petroleum; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases