title: The effect of surgical drainage materials on colonic healing.
abstract: The effect of surgical drainage materials on rat colonic healing has been investigated in a prospective randomized and controlled study. Latex, silicone rubber (Silastic), polyvinylchloride (PVC) and polytetrafluoroethylene (Teflon) tubes were implanted alongside a colonic anastomosis and compared with a 'no drain' group using mechanical and histological assessments. There was a significant increase in anastomotic leakage in the latex group in which there appears to be a local inhibition of healing. Silastic, PVC and Teflon were not found to interfere with healing. The continued use of latex drains in colonic surgery is therefore questioned.
mesh_terms: D000818:Animals; D003106:Colon / Q000601:surgery*; D004322:Drainage / Q000009:adverse effects / Q000295:instrumentation*; D007840:Latex / Q000009:adverse effects; D008297:Male; D008954:Models, Biological; D011138:Polytetrafluoroethylene / Q000009:adverse effects; D011143:Polyvinyl Chloride / Q000009:adverse effects; D011446:Prospective Studies; D011897:Random Allocation; D051381:Rats; D012826:Silicone Elastomers / Q000009:adverse effects; D014945:Wound Healing
chemical_list: D007840:Latex; D012826:Silicone Elastomers; D011138:Polytetrafluoroethylene; D011143:Polyvinyl Chloride