Malondialdehyde production by erythrocytes from alcoholic and non-alcoholic subjects.
A survey of the capacity of erythrocyte suspensions to handle a standard hydrogen peroxide oxidative load was made in a population of white male hospitalized alcoholics and non-hospitalized, non-alcoholic subjects. As measured by malondialdehyde (MDA) production, the capacity to handle this oxidation load was decreased in a significant percentage of individuals with a positive family history of alcoholism and who have experienced problems with alcohol sufficient to produce cytopathological changes and to require hospitalization.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D005609:Free Radicals; D006801:Humans; D008297:Male; D008314:Malonates / Q000378:metabolism*; D008315:Malondialdehyde / Q000378:metabolism*; D008875:Middle Aged; D013315:Stress, Psychological / Q000378:metabolism
D005609:Free Radicals; D008314:Malonates; D008315:Malondialdehyde