title: Streptococcal involvement in childhood acute glomerulonephritis: a review of 20 cases at admission.
abstract: Twenty children sequentially admitted to the paediatric ward, Tauranga Hospital, with a diagnosis of acute glomerulonephritis, are reviewed for evidence of recent streptococcal infection as at admission. Sixteen children (80 percent) were shown to have at least one streptococcal antibody titre (ASO and anti-DNase B) elevated above the upper limit of normal for the population. Two children had negligible antibody levels detected. Case histories and/or cultural results provided additional supportive evidence for recent streptococcal infection. Serotypes of recognised nephritogenic potential were isolated from five patients.
mesh_terms: D000293:Adolescent; D000917:Antibody Formation; D000989:Antistreptolysin / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003851:Deoxyribonucleases / Q000276:immunology; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D006801:Humans; D008297:Male; D009520:New Zealand; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D013297:Streptococcus pyogenes / Q000302:isolation & purification
chemical_list: D000989:Antistreptolysin; D003851:Deoxyribonucleases; C020069:deoxyribonuclease B