title: Interlaboratory bilirubin variability.
abstract: Stabilized liquid quality control sera, some with elevated bilirubin concentrations, were distributed to laboratories for total and conjugated (direct) bilirubin analyses. Interlaboratory variability was high; for example, results ranged from 10.9 to 24.0 mg/100 ml for a serum with a mean bilirubin concentration of 18.1 mg/100 ml. Coefficients of variation were typically 10% to 12% for total bilirubin ad approximately 24% for conjugated bilirubin analyses. It is believed that these stabilized sera, when used as quality control materials, can help reduce the unacceptably large interlaboratory variability found in this study.
mesh_terms: D001663:Bilirubin / Q000097:blood*; D001774:Blood Chemical Analysis / Q000379:methods / Q000592:standards*; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000097:blood; D007753:Laboratories / Q000592:standards; D011786:Quality Control; D013048:Specimen Handling
chemical_list: D001663:Bilirubin