title: Ophthalmic fluorophotometry: a new solid state fluorophotometer.
abstract: A new low-voltage ophthalmic fluorophotometer is described. A solid state photodetector has been combined with a high-gain, low-noise amplification and synchronous detection system to develop a stable, relatively inexpensive instrument. Reliable measurements of sodium fluorescein concentration in the eye can be made down to 100 ng/ml (0.26 mumol/l) which allows the estimation of corneal permeability and tear flow rates. Preliminary measurements of tear turnover rate using the fluorophotometer are presented.
mesh_terms: D003315:Cornea / Q000502:physiology*; D004581:Electronics; D019793:Fluorescein; D005452:Fluoresceins; D006801:Humans; D019721:Ophthalmoscopes; D010539:Permeability; D013053:Spectrophotometry; D013666:Tears / Q000502:physiology*
chemical_list: D005452:Fluoresceins; D019793:Fluorescein