Effect of a delta 5-homo-aza-steroidal ester in P388 and L1210 murine leukemias.
3 beta-Hydroxy-13 alpha-amino-13,17-seco-5-androsten-17-oic-13,17-lactam P-N,N-bis-(2-chloroethyl)-amino phenylacetate gives results in P388 and L1210 leukemias in mice, by the intraperitoneal route of administration.
D000818:Animals; D000970:Antineoplastic Agents; D001378:Azasteroids / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D005260:Female; D007274:Injections, Intraperitoneal; D007928:Lethal Dose 50; D007939:Leukemia L1210 / Q000188:drug therapy*; D007941:Leukemia P388 / Q000188:drug therapy*; D007942:Leukemia, Experimental / Q000188:drug therapy*; D008017:Life Expectancy; D051379:Mice; D008815:Mice, Inbred Strains; D009588:Nitrogen Mustard Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D010648:Phenylacetates / Q000494:pharmacology; D013260:Steroids, Heterocyclic / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D001378:Azasteroids; D009588:Nitrogen Mustard Compounds; D010648:Phenylacetates; D013260:Steroids, Heterocyclic; C008826:phenacid; C033499:3-(((4-(bis(2-chloroethyl)amino)phenyl)acetyl)oxy)-17a-aza-D-homoandrost-5-en-17-one