title: Effects of phenol, 2,4-dimethylphenol, 2,4-dichlorophenol, and pentachlorophenol on embryo, larval, and early-juvenile fathead minnows (Pimephales promelas).
abstract: Embryos of fathead minnows were more resistant to phenol, 2,4-dimethylphenol (2,4-DMP), 2,4-dichlorophenol (2,4-DCP), and pentachlorophenol (PCP) than were larval or juvenile life stages. Growth of 28-day-old fish was the most sensitive indicator of stress during exposures to phenol, 2,4-DMP, and PCP, whereas survival was the most sensitive indicator of toxic effects from 2,4-DCP exposure. Based on these effects, the estimated maximum acceptable toxicant concentration for fathead minnows in Lake Superior water lies between 1,830 and 3,570 micrograms/L for phenol; 1,970 and 3,110 micrograms/L for 2,4-DMP; 290 and 460 micrograms/L for 2,4-DCP; and 44.9 and 73.0 micrograms/L for PCP.
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000633:toxicity*; D002733:Chlorophenols / Q000633:toxicity*; D004625:Embryo, Nonmammalian / Q000187:drug effects; D005399:Fishes; D007814:Larva / Q000187:drug effects; D010416:Pentachlorophenol / Q000633:toxicity*; D010636:Phenols / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity; D014992:Xylenes
chemical_list: D000890:Anti-Infective Agents; D002733:Chlorophenols; D010636:Phenols; D014874:Water Pollutants, Chemical; D014992:Xylenes; C027804:2,4-dimethylphenol; D010416:Pentachlorophenol; C004762:2,4-dichlorophenol