title: Mutagens in larger fungi. II. The mutagenicity of commercial pickled Lactarius necator in the Salmonella assay.
abstract: In the course of an ongoing screening of larger mushrooms for the occurrence of chemical mutagens, 33 out of 48 species tested exhibited a significant direct mutagenic activity in the Salmonella/microsome assay (Sterner et al., 1982). (No mutagens requiring metabolic activation were indicated.) These findings are of some concern, since mushrooms are used extensively as food in many areas, and there are strong indications that carcinogens in food are of considerable importance in cancer aetiology (Sugimura, 1979). A recent communication by Knuutinen and von Wright (1982) on the mutagenicity of 4 Lactarius species collected in Finland prompts us to report our own results from mutagenicity tests with commercially preserved (pickled) Lactarius necator.
mesh_terms: D001487:Basidiomycota / Q000032:analysis*; D005511:Food Handling; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis* / Q000494:pharmacology; D009154:Mutation; D012486:Salmonella typhimurium / Q000187:drug effects; D013045:Species Specificity
chemical_list: D009153:Mutagens