Treatment of recurrent antibiotic-associated pseudomembranous colitis.
Eleven patients with relapses of antibiotic-associated pseudomembranous colitis were treated with a tapering dose schedule of vancomycin and cholestipol. All patients responded and have continued to be asymptomatic for follow-up periods of at least 6 wk. This tapering dose of vancomycin in conjunction with cholestipol appears to be warranted in patients with relapses of antibiotic-associated pseudomembranous colitis.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003015:Clostridium Infections / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014640:Vancomycin / Q000008:administration & dosage / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D014640:Vancomycin