title: The involuting lichenoid plaque.
abstract: Progressive involution and subsequent regression of a plaque that showed the characteristic histologic findings of solitary lichen planus-like keratosis were observed in five patients. In each lesion, involution took place during a four- to eight-week period. In four patients, the lesion arose in a preexisting pigmented macule. Evolution into a plaque-like lesion coincided with the development of the inflammatory process. Origin from a preexisting lesion suggests that the lichenoid plaque is not an independent entity but a stage in the involution of the preexisting pigmented macule. The lichenoid inflammatory process resembles a delayed hypersensitivity reaction and seems to represent a cell-mediated rejection reaction.
mesh_terms: D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007642:Keratosis / Q000276:immunology / Q000473:pathology*; D008010:Lichen Planus / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D012075:Remission, Spontaneous