[Components of the creatine kinase system in the myocardium with experimental disturbance of coronary blood flow].
Certain key parameters of energy metabolism in a complex mechanism of energy transport in the myocardium cells were studied in experiments on dogs with dosed limitation of the coronary blood flow (by 90%) as well as in experiments on rabbits with the intravenous injection of vasopressin (0.2 units per 1 kg of mass). Animals of all groups under study revealed essential changes in the content of creatine phosphate and in the activity of creatine phosphokinase as compared with the control groups. A possible role of creatine phosphokinase is discussed in the processes of myocardium function energy supply under conditions of creatine phosphate deficiency during a slightly pronounced ischemia.
D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects; D003402:Creatine Kinase / Q000378:metabolism*; D004285:Dogs; D004734:Energy Metabolism; D006321:Heart / Q000503:physiopathology; D007511:Ischemia / Q000503:physiopathology*; D010725:Phosphocreatine / Q000378:metabolism; D014667:Vasopressins / Q000494:pharmacology*
D010725:Phosphocreatine; D014667:Vasopressins; D003402:Creatine Kinase
Komponenty kreatinkinaznoĭ sistemy v miokarde pri éksperimental'nom narushenii koronarnogo krovotoka.