Chronic intestinal ischemia associated with oral contraceptive use.
A 48-yr-old woman with chronic intestinal ischemia and a long history of oral contraceptive use is reported. She presented with a 6-month history of severe diarrhea, abdominal pain, and weight loss. Abdominal arteriography revealed occlusion of the celiac axis at its origin and 90% stenosis of the superior mesenteric artery. This chronic arterial lesion has not been previously noted in association with the use of oral contraceptive agents in otherwise healthy women. The patient's isolated arterial lesions proved amenable to successful surgical bypass. Postoperatively she became completely asymptomatic and has remained so on long-term follow-up.
D000328:Adult; D002445:Celiac Artery / Q000473:pathology; D002908:Chronic Disease; D003251:Constriction, Pathologic; D003276:Contraceptives, Oral / Q000009:adverse effects*; D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007422:Intestines / Q000098:blood supply*; D007511:Ischemia / Q000139:chemically induced*; D008638:Mesenteric Arteries; D008641:Mesenteric Vascular Occlusion / Q000139:chemically induced; D008656:Mestranol / Q000009:adverse effects*; D008875:Middle Aged; D009641:Norethynodrel / Q000009:adverse effects*
D003276:Contraceptives, Oral; D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal; C008124:Infecundin; D009641:Norethynodrel; D008656:Mestranol