title: Acute leukemia as a natural sequel to primary thrombocythemia.
abstract: A 70-year-old woman had primary thrombocythemia for three years. She received no specific therapy, but developed acute leukemia. The progression of primary thrombocythemia to leukemia is rare and has not been well-documented in the absence of preceding therapy.
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D007938:Leukemia / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D009196:Myeloproliferative Disorders / Q000150:complications*; D013997:Time Factors