[Inactivation of choline receptors induced by membrane depolarization].
It was found that membrane depolarization of Lymnaea stagnalis neurons inhibited the conductance induced by acetylcholine (ACh). This phenomenon (cholinoreceptor inactivation) was shown to be connected with a potential influence on none of the following characteristics: reversal potential (Er) of the ACh-induced currents, affinity of ACh to the receptors, ACh concentration near the receptive membrane surface, and desensitization rate.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D007700:Kinetics; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D011950:Receptors, Cholinergic / Q000502:physiology*
D011950:Receptors, Cholinergic; D000109:Acetylcholine
Inaktivatsiia kholkinoretseptorov, vyzyvaemaia membrannoĭ depoliarizatsieĭ.