Role of viral glycoproteins in haemolysis by influenza B virus.
Influenza B virus exhibited haemolytic activity at low pH, but the pH profile for its activity varied from strain to strain. The results of selective heat-inactivation of the enzyme activity of neuraminidase (NA) or elimination from virions of the enzyme-active portion of the NA molecule by trypsin digestion, suggest that proteolytically cleaved haemagglutinin, but not enzyme activity of NA, is essential for haemolysis by influenza B virus.
D000818:Animals; D002645:Chickens / Q000097:blood; D006389:Hemagglutinins, Viral; D006461:Hemolysis; D006863:Hydrogen-Ion Concentration; D009439:Neuraminidase / Q000502:physiology*; D009975:Orthomyxoviridae / Q000201:enzymology / Q000502:physiology*
D006389:Hemagglutinins, Viral; D009439:Neuraminidase