Lysozyme, intradermal diffusion of india ink and peritoneal capillary permeability in mice.
Hen egg white lysozyme injected intracutaneously into mice inhibits the intradermal diffusion of India Ink. The effect of lysozyme persists in presence of hyaluronidase. Lysozyme injected i.p. into mice inhibits acetic acid (i.p.) induced leakage of Pontamine Sky Blue into the abdominal cavity. The data suggest that lysozyme might be tried for applications outside the microbiological field.
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D002244:Carbon; D004396:Coloring Agents / Q000378:metabolism; D004058:Diffusion; D004529:Egg White; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology; D008297:Male; D051379:Mice; D009113:Muramidase / Q000494:pharmacology*
D004396:Coloring Agents; C028433:chinese ink; D002244:Carbon; D009113:Muramidase; D006821:Hyaluronoglucosaminidase