Jk(a-b-) red blood cells resist urea lysis.
Falsely high automated platelet counts in a patient with aplastic anemia were found to be due to increased resistance of the red blood cells to urea lysis. The patient's blood group Jk(a-b-). Further investigation revealed that this phenomenon occurred with all of eight bloods of the phenotype Jk(a-b-) but not with red blood cells of other phenotypes tested. We therefore report an association of a rare blood group phenotype with unusual red blood cell behavior in vitro.
D000328:Adult; D001789:Blood Group Antigens; D004906:Erythrocyte Count / Q000295:instrumentation; D004912:Erythrocytes / Q000187:drug effects*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D007667:Kidd Blood-Group System; D008297:Male; D010139:Pacific Islands / Q000208:ethnology; D010976:Platelet Count / Q000295:instrumentation; D014508:Urea / Q000494:pharmacology*
D001789:Blood Group Antigens; D007667:Kidd Blood-Group System; D014508:Urea