Achalasia in siblings.
The occurrence of achalasia in two brothers who were successfully treated by oesophagomyotomy is reported. There was no evidence of oesophageal motor dysfunction in their parents or two other siblings who were also studied. The possibility that genetic factors may be important in the aetiology of achalasia is discussed.
D000293:Adolescent; D000328:Adult; D004931:Esophageal Achalasia / Q000235:genetics* / Q000503:physiopathology / Q000601:surgery; D004947:Esophagus / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged