Adrenal cortical carcinoma in a 4-year-old child: temporal changes in steroid secretion.
A case is reported of a 4-year-old female with an adrenal cortical carcinoma that developed at the site of a previously removed adrenal gland. Initially, the tumor was only virilizing, but with time, it also became the source of a large secretion of glucocorticoids and, to a lesser degree, mineralocorticoids. It is one of the largest and most functional tumors described in a child.
D000306:Adrenal Cortex Neoplasms / Q000097:blood / Q000378:metabolism*; D002277:Carcinoma / Q000378:metabolism*; D002675:Child, Preschool; D005260:Female; D005938:Glucocorticoids / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D013739:Testosterone / Q000097:blood
D005938:Glucocorticoids; D013739:Testosterone; D006854:Hydrocortisone