Bone marrow phagocytosis in sarcoidosis.
The phagocytic activity of the bone marrow monocytes and macrophages was studied in 22 patients with sarcoidosis, 28 patients with Hodgkin's and non-Hodgkin's malignant neoplasms, and 14 controls. Although phagocytosis of RBCs and WBCs and platelets were seen in all bone marrow specimens, the activity was considerably increased in some patients with stage I and stage II sarcoidosis. This observation may reflect the presence of an unusual host response to unknown antigens in patients with sarcoidosis.
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000503:physiopathology*; D001854:Bone Marrow Cells; D001856:Bone Marrow Examination; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000503:physiopathology; D006801:Humans; D008171:Lung Diseases / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology; D010587:Phagocytosis; D012507:Sarcoidosis / Q000473:pathology / Q000503:physiopathology*