Spontaneous uterine neoplasms in the fat sand rat (Psammomys obesus).
Sacrifice of 69 fat sand rats (Psammomys obesus) bred at the Hebrew University--Hadassah Medical School, yielded 19 cases with spontaneous uterine tumours. These consisted of 5 leiomyomas, 3 endometrial polyps, 10 adenofibromas and one possibly malignant mixed mesodermal tumour. The relatively high incidence of adenofibromas histologically resembling the human neoplasm, could make this animal a useful model for further study of Müllerian mixed tumours.
D000232:Adenofibroma / Q000473:pathology; D000818:Animals; D003411:Arvicolinae; D005260:Female; D007889:Leiomyoma / Q000473:pathology; D011127:Polyps / Q000473:pathology; D012376:Rodent Diseases / Q000473:pathology*; D014594:Uterine Neoplasms / Q000662:veterinary*