Chest pain and rate-dependent left bundle branch block in patients with normal coronary arteriograms.
A triad of exertional chest discomfort, transient rate-dependent left bundle branch block (LBBB), and normal coronary arteries is presented in seven consecutive patients. Although the clinical symptoms resembled effort angina, qualities atypical of classic angina pectoris were commonly noted: 1) the onset was always abrupt; and 2) the pain was local, never radiating; 3) palpitation; and 4) "walk through" phenomenon were often present. The abrupt pain took place simultaneously with the appearance of LBBB induced by physical exercise in all seven patients. Atrial pacing or spontaneous resting heart rate changes produced similar sensations and LBBB in four of the five patients examined in this way. Similarly, in the same four patients kinetocardiographic recordings disclosed a sudden occurrence of paradoxic cardiac movement at the moment LBBB and chest pain appeared. The paradoxic systolic motion disappeared at reversion to normal conduction.
D000328:Adult; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002037:Bundle-Branch Block / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial; D017023:Coronary Angiography; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007702:Kinetocardiography; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion