[Effect of acute furosemide and sodium chloride load on the hormone level of the blood of ischemic heart disease patients].
In group of 43 patients with ischaemic heart disease and coronary atherosclerosis and in 18 practically healthy individuals administration of a single intravenous dose of furosemide (40 mg) in one group, and of 10 ml 10% sodium chloride in the other was employed to study the activity of various hormones in the blood. It was established that in patients with ischaemic heart disease dissociation of the functional state of the hormonal systems, ensuring integration of the main haemodynamic and water-salt parameters takes place. The degree of lesion of these adaptive mechanisms is related to the severity of the disease, its duration, and the initial hormonal background. Furosemide and sodium chloride given in these doses permit to detect more clearly the disorders supervening in these systems.
D000328:Adult; D003327:Coronary Disease / Q000097:blood*; D005260:Female; D005665:Furosemide / Q000008:administration & dosage; D006706:Homeostasis / Q000187:drug effects; D006728:Hormones / Q000097:blood*; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood; D008297:Male; D012965:Sodium Chloride / Q000008:administration & dosage; D013997:Time Factors
D006728:Hormones; D012965:Sodium Chloride; D005665:Furosemide
Vliianie ostrykh nagruzok furosemidom i khloristym natriem na uroven' riada gormonov v krovi bol'nykh ishemicheskoĭ bolezn'iu serdtsa.