Multicentric giant pigmented nevi of the scalp with local invasion of the cranium and dura mater.
A giant pigmented nevus grew rapidly as several discrete tumors at different locations in the scalp of a 5-mo-old child. One tumor located beneath the skin in the occipital calvarium invaded bone and dura mater. Five years after the excision of the larger tumors, the child was asymptomatic having no further evidence of recurrence or continued growth of the neoplasma. In view of the propensity for giant pigmented nevi to concomitantly involve the central nervous system (leptomeningeal melanocytosis) and to rarely give rise to melanomas, this case is reported as demonstrating the subsequent benign behavior of a tumor that at first presented alarming growth, suggesting malignancy.
D006801:Humans; D007223:Infant; D008297:Male; D009361:Neoplasm Invasiveness; D009508:Nevus, Pigmented / Q000151:congenital / Q000473:pathology* / Q000601:surgery; D012535:Scalp; D012878:Skin Neoplasms / Q000151:congenital / Q000473:pathology* / Q000601:surgery