Results of surgical and conservative therapy on patients with nephrolithiasis and chronic renal insufficiency.
In a series of 264 inpatients with nephrolithiasis and chronic renal insufficiency, 159 received follow-up care between 1 and 14 years (4.3 years on the average) after primary hospitalization. 59 of these 159 patients had to undergo nephrectomy in the course of calculus disease. Follow-up examinations showed no deterioration in 60 patients and a further 64 showed clear symptoms of improved renal function. In 23 patients renal function deteriorated and 11 of them had to be accepted in chronic dialysis. Special emphasis is placed on the relevance of thorough metaprophylaxis after calculus removal. Stone analyses of patients with renal insufficiency showed a high share of infectious stones (struvite and carbonic apatite) as well as of uric acid calculi. For that reason especially these patients require an intensive follow-up treatment.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002951:Citrates / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000601:surgery*; D007669:Kidney Calculi / Q000150:complications / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D006435:Renal Dialysis
D000900:Anti-Bacterial Agents; D002951:Citrates; D000493:Allopurinol