title: Apical changes and scarring in keratoconus as related to contact lens fitting techniques.
abstract: Seven keratoconus patients were fitted with gas-permeable lenses, one eye with a large apical bearing lens and the other with a small apical clearance lens. Within 12 months, 4 of the 7 eyes wearing the large flat technique developed corneal scarring, while no scarring developed in the eyes fitted with the apical clearance technique.
mesh_terms: D002921:Cicatrix / Q000209:etiology; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects* / Q000592:standards; D003316:Corneal Diseases / Q000209:etiology*; D006801:Humans; D007640:Keratoconus / Q000628:therapy*; D008768:Methylmethacrylates; D010100:Oxygen; D010539:Permeability; D011108:Polymers; D012828:Silicones
chemical_list: D008768:Methylmethacrylates; D011108:Polymers; D012828:Silicones; D010100:Oxygen