Expression of beneficial blood transfusion effect in dogs is dependent upon immunosuppressants used.
To achieve the beneficial blood transfusion effect, postoperative immunosuppression with Aza/Pred is mandatory. When CY-A is used for immunosuppression during a limited time, the transfusion effect is not manifested; however CY-A does not lessen the effect in animals given Aza/Pred. In nontransfused recipients, the combination of Aza/Pred and CY-A did not give better graft survival than CY-A alone.
D000818:Animals; D001379:Azathioprine / Q000627:therapeutic use; D001803:Blood Transfusion; D003524:Cyclosporins / Q000627:therapeutic use; D004285:Dogs; D004306:Dose-Response Relationship, Immunologic; D004359:Drug Therapy, Combination; D006085:Graft Survival / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation; D011182:Postoperative Care; D011239:Prednisolone / Q000627:therapeutic use
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine