Emperipolesis by megakaryocytes in patients with non-Hodgkin's lymphoma and megaloblastic anemia.
Emperipolesis, i.e. engulfment of blood cells by megakaryocytes, was observed in one patient with non-Hodgkin's lymphoma and in one patient with megaloblastic anemia. In the first patient, the engulfed cells were lymphocytes, whereas in the second one they were granulocytes. Transmission (TEM) and scanning electron microscopic (SEM) examinations showed that blood cells tend to make a rosette-like formation around the megakaryocytes engaged in this phenomenon.
D000368:Aged; D000748:Anemia, Macrocytic / Q000473:pathology*; D000749:Anemia, Megaloblastic / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000502:physiology*; D008223:Lymphoma / Q000473:pathology*; D008533:Megakaryocytes / Q000502:physiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged