Gastro-Conray does not alter resting lower oesophageal sphincter pressure in normal human subjects.
The effect of ingestion of 60 ml sodium iothalamate (Gastro-Conray; Maybaker)--a radiographic contrast medium--on resting lower oesophageal sphincter (LOS) pressure was studied in 10 normal human volunteers. Compared with a barium meal, which does cause a fall in LOS pressure, Gastro-Conray did not affect the sphincter tone. The importance of this is discussed.
D000293:Adolescent; D000328:Adult; D003287:Contrast Media / Q000494:pharmacology*; D004943:Esophagogastric Junction / Q000187:drug effects*; D005189:False Positive Reactions; D006801:Humans; D007483:Iothalamic Acid / Q000494:pharmacology*
D003287:Contrast Media; D007483:Iothalamic Acid