Inhibition of phosphatidylethanolamine N-methylation by 3-deazaadenosine stimulates the synthesis of phosphatidylcholine via the CDP-choline pathway.
D000818:Animals; D002794:Choline / Q000031:analogs & derivatives* / Q000378:metabolism; D003566:Cytidine Diphosphate Choline / Q000378:metabolism*; D007536:Isomerism; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008715:Methionine / Q000378:metabolism; D008745:Methylation; D010713:Phosphatidylcholines / Q000096:biosynthesis*; D010714:Phosphatidylethanolamines / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012263:Ribonucleosides / Q000494:pharmacology*; D014372:Tubercidin / Q000494:pharmacology*
D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D012263:Ribonucleosides; C018258:3-deazaadenosine; D003566:Cytidine Diphosphate Choline; D008715:Methionine; D014372:Tubercidin; D002794:Choline