title: Flow measurement of blood radioactivity in animals.
abstract: In order to permit flow measurement of blood radioactivity in an animal after establishing extracorporeal circulation, counting cells were constructed of various plastic scintillator materials. The cell was placed in a liquid scintillation spectrometer replacing the sample vial. Stable and reproducible counting rates were obtained only with cells made of blue Altustipe plastic. The counting efficiency was 1.8%. Using this detection system, continuous records were produced of blood radioactivity in miniature pigs after administration of 14C-urethane and [14C]methyl-piperazinyl pyrazino benzoxazepine maleate.
mesh_terms: D000818:Animals; D002250:Carbon Radioisotopes; D006993:Hypnotics and Sedatives / Q000097:blood; D007700:Kinetics; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D012588:Scintillation Counting / Q000379:methods*; D013552:Swine; D014520:Urethane / Q000097:blood
chemical_list: D002250:Carbon Radioisotopes; D006993:Hypnotics and Sedatives; D004364:Pharmaceutical Preparations; D014520:Urethane