Changes in serotonin receptors in different brain regions after light exposure of dark-reared rats.
Male rats dark-reared from birth until 50 days of age and then exposed to light for 3 h show significant increases in specific [3H]serotonin (5-[3H]HT) binding to P2 membranes from visual and motor cortex and superior colliculus (25, 65 and 23% respectively) as compared with normal and dark-reared littermates. These increases are transient and return to normal levels after 7 days. The role of 5-HT as a transmitter in the visual system is discussed.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D003623:Dark Adaptation; D008027:Light; D008297:Male; D009044:Motor Cortex / Q000378:metabolism; D009115:Muridae; D011985:Receptors, Serotonin / Q000378:metabolism*; D012683:Sensory Deprivation / Q000502:physiology*; D012701:Serotonin / Q000378:metabolism; D013477:Superior Colliculi / Q000378:metabolism; D014793:Visual Cortex / Q000378:metabolism; D014795:Visual Pathways / Q000378:metabolism; D014796:Visual Perception / Q000502:physiology
D011985:Receptors, Serotonin; D012701:Serotonin