Glycosylated hemoglobin in Mystromys albicaudatus: a diabetic animal model.
Glycosylated hemoglobin was measured in Mystromys albicaudatus, a rodent model of diabetes mellitus, using a newly developed colorimetric assay. The mean glycosylated hemoglobin for non-diabetic Mystromys (n = 321) was 14.8 nmol hydroxymethylfurfural / 10 mg hemoglobin which is similar to that obtained in non-diabetic humans. Animals with a glycosylated hemoglobin value greater than 19 nmol hydroxymethylfurfural / 10 mg hemoglobin were characterized as diabetics. Significant correlations were found between glycosylated hemoglobin and both plasma glucose and urine glucose levels.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003124:Colorimetry / Q000379:methods; D003920:Diabetes Mellitus / Q000097:blood / Q000662:veterinary*; D004195:Disease Models, Animal; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006029:Glycosuria; D008297:Male; D012376:Rodent Diseases / Q000097:blood*; D012377:Rodentia
D001786:Blood Glucose; D006442:Glycated Hemoglobin