Microbial conversion of saframycin A to 25-dihydrosaframycin A and 21-decyano-25-dihydrosaframycin A (25-dihydrosaframycin B) and their biological activities.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology; D007546:Isoquinolines / Q000378:metabolism / Q000494:pharmacology; D051379:Mice; D012244:Rhodospirillaceae / Q000378:metabolism*; D013329:Structure-Activity Relationship
D000903:Antibiotics, Antineoplastic; D007546:Isoquinolines; C034620:25-dihydrosaframycin A; C034621:21-decyano-25-dihydrosaframycin A; C026925:saframycin A