title: Real-time ultrasound of the placenta in assessment of fetal pulmonic maturity.
abstract: The use of ultrasound is a noninvasive method of assessing fetal maturity. However, in order for it to be a substitute for amniocentesis, a high degree of accuracy is required. Static ultrasound examination of placental development has revealed certain patterns of maturity which have suggested to be predictors of fetal pulmonary maturity. This study analyzes 100 patients near term for the accuracy of placental grade in predicting pulmonary maturity when measured by the lecithin/sphingomyelin ratio and by clinical development of the respiratory distress syndrome in the neonate. A mature placental grade (Grade III) determined by real-time sonography corresponded to fetal lung maturity in all cases (n = 15). Placental grade as determined by this methodology appeared to be an accurate predictor of fetal maturity in the population examined.
mesh_terms: D000653:Amniotic Fluid / Q000032:analysis; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology*; D010713:Phosphatidylcholines / Q000032:analysis; D010920:Placenta / Q000502:physiology*; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis; D013109:Sphingomyelins / Q000032:analysis; D014463:Ultrasonography
chemical_list: D010713:Phosphatidylcholines; D013109:Sphingomyelins