title: Intravenous cholescintigraphy using Tc-99m-labeled agents in the diagnosis of choledochal cyst.
abstract: Twelve patients with choledochal cyst have undergone intravenous radionuclide cholescintigraphy (IVRC) with Tc-99m-labeled HIDA or PG before surgery. The most characteristic findings are: (1) A round or ovoid photon-deficient area in the region of the gallbladder in the early images; (2) progressive accumulation of radioactivity in the same region in later images, especially at 2 hr after injection; (3) the long axis of this particular area directed downward and to the patient's left from the right midclavicular line, suggesting the direction of the common bile duct; and (4) persistent pooling of the tracer up to 24 hr, even after a fatty meal. By these criteria, correct diagnoses have been made preoperatively in ten of 12 cases (83.3%). We conclude that IVRC using Tc-99m HIDA or Tc-99m PG is an excellent first-line diagnostic tool for choledochal cyst.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003135:Common Bile Duct / Q000000981:diagnostic imaging; D003137:Common Bile Duct Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D003560:Cysts / Q000000981:diagnostic imaging* / Q000601:surgery; D005069:Evaluation Studies as Topic; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging; D005971:Glutamates; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011730:Pyridoxal / Q000031:analogs & derivatives*; D011877:Radionuclide Imaging; D013667:Technetium; D019780:Technetium Tc 99m Lidofenin; D013997:Time Factors
chemical_list: D005971:Glutamates; D007098:Imino Acids; D015609:Organotechnetium Compounds; C011551:technetium Tc 99m pyridoxylidene glutamate; D011730:Pyridoxal; D019780:Technetium Tc 99m Lidofenin; D013667:Technetium