The mycolic acids of Mycobacterium leprae harvested from experimentally infected nine-banded armadillos.
Mycolic acid methyl esters were prepared from defatted cells of armadillo-derived Mycobacterium leprae and analysed by thin-layer and high-performance liquid chromatography, proton magnetic resonance spectrometry and mass spectroscopy. The first type of mycolic acid characterized was an "alpha-mycolate" having two cis-cyclopropane rings, a 78-carbon main component and an overall size-range of 72 to 83 carbons. Ketomycolates, with an 83-carbon main component, were the only other type of mycolate isolated; the major 79- to 87-carbon series of ketomycolates apparently contained a single trans-cyclopropane and the minor 80- to 86-carbon series had a cis-cyclopropane function.
D000818:Animals; D001135:Armadillos / Q000382:microbiology; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009166:Mycobacterium leprae / Q000032:analysis*; D009171:Mycolic Acids / Q000032:analysis*
D009171:Mycolic Acids