Chromosome evaluation of Angus calves with unilateral congenital cleft lip and jaw (cheilognathoschisis).
Two purebred Angus calves with unilateral cleft lip and jaw were karyotyped and anatomically described. Both calves, 1 male and 1 female, were from the same farm and were born in March and April 1980. The defect was most pronounced in the female calf. Both calves exhibited an elevated midline of the hard palate. The female calf also manifested characteristics indicative of proportionate dwarfism. Karyotypes were constructed after a 72-hour culture of peripheral blood. The 2N number was 60 with no apparent chromosome abnormality. The coefficient of relationship between the 2 affected calves was calculated to be 0.78%. The cause of the defect could not be ascertained from the limited data available.
D000014:Abnormalities, Drug-Induced / Q000662:veterinary; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D002971:Cleft Lip / Q000235:genetics* / Q000473:pathology; D005260:Female; D007569:Jaw Abnormalities / Q000235:genetics* / Q000473:pathology; D007621:Karyotyping / Q000662:veterinary*; D008297:Male; D010375:Pedigree