Effect of oral terbutaline on exercise-induced asthma.
Spirometry before and after a treadmill exercise two hours after oral administration of 2.5-5.0 mg of terbutaline or placebo disclosed that terbutaline produced a highly significant protective effect against exercise-induced asthma. In 14 asthmatic youngsters decreases in FEV1, PEFR or FEF25-75 of at least 15% followed exercise after placebo.
D000284:Administration, Oral; D001249:Asthma / Q000188:drug therapy*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy*; D001794:Blood Pressure / Q000187:drug effects; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume; D006339:Heart Rate / Q000187:drug effects; D049668:History, 15th Century; D006801:Humans; D006813:Humidity; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D010366:Peak Expiratory Flow Rate; D011674:Pulse / Q000187:drug effects; D013726:Terbutaline / Q000008:administration & dosage / Q000627:therapeutic use*
D013726:Terbutaline