Versatile semiautomated sample processor and gamma counter to increase radioimmunoassay efficiency.
We describe a semiautomated batch-assay system designed to increase the speed and ease of performing radioimmunoassays while maintaining good accuracy and precision. The main components are a programmable pipetting unit (sample processor) and a gamma counter capable of simultaneously counting radioactivity in 12 samples. The processor uses prearranged sets of as many as 24 disposable pipette tips, which eliminates carryover between samples, and features a horizontal shaker and magnetic stirrer; 50 different assay protocols can be selected. Batches of tubes are easily transferred from the sample processor to the incubator and centrifuge. The gamma counter is controlled by a microprocessor, which is also used for data processing. Because the system is based on discrete rather than continuous-flow analysis and because of the ease with which consecutive samples can be processed, more than one operation and several different assays can be accommodated simultaneously, which saves time considerably.
D004964:Estriol / Q000097:blood; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008838:Microcomputers; D010928:Placental Lactogen / Q000097:blood; D011247:Pregnancy; D011863:Radioimmunoassay / Q000295:instrumentation*; D013997:Time Factors
D010928:Placental Lactogen; D004964:Estriol