Intralesional corticosteroid injection for infantile adnexal hemangioma.
I treated ten patients who had adnexal hemangioma with intralesional injections of corticosteroid. A marked and lasting regression of the hemangioma occurred in eight of the patients and one had a moderate response. This treatment also proved effective in preventing amblyopia in infants who had large hemangiomas that occluded the visual axis, and often resulted in a reversal of the astigmatism induced by these tumors. There were no complications. The advantages of intralesional corticosteroid injection include ease of administration, speed of action, apparent freedom from adverse side effects, and repeatability.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000550:Amblyopia / Q000150:complications; D001623:Betamethasone / Q000627:therapeutic use; D002675:Child, Preschool; D005142:Eyelid Neoplasms / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007279:Injections, Subcutaneous; D008297:Male; D014221:Triamcinolone / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D014221:Triamcinolone; D001623:Betamethasone