title: [Effect of acetylcholine on gastric secretory function and its vascular tonus].
abstract: Depending on doses, acetylcholine can produce the same effects in respect to activation of the stomach gland secretion either in hypodermic or intramuscular administration or acting from the surface of the stomach mucosa. Combination of acetylcholine and histamine produces the same secretory effect as food irritation. In acute experiments on dogs i.v. administration of acetylcholine causes a temporary contraction of vessels and a decrease of partial oxygen pressure, whereas in chronic experiments the same combination of the agents increases partial oxygen pressure which is suggestive of a decrease in the tone of stomach mucosa vessels.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D003714:Denervation; D004285:Dogs; D005753:Gastric Mucosa / Q000098:blood supply / Q000187:drug effects* / Q000378:metabolism; D006632:Histamine / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D010313:Partial Pressure; D013270:Stomach / Q000294:innervation; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects*
chemical_list: D006632:Histamine; D000109:Acetylcholine
vernacular_title: Vliianie atsetilkholina na sekretornuiu frnktsiiu zheludka i tonus ego sosudov.