Postirradiation sarcomatous transformation of a pituitary adenoma: a combined pituitary tumor. Case report.
A case is reported in which a fibrosarcoma developed 20 years after irradiation of a pituitary chromophobe adenoma. This rare lesion, like most of the other documented postirradiation pituitary sarcomas, was a combination of fibrosarcoma and pituitary adenoma. These lesions tend to behave in a characteristic fashion, with onset after a long latent interval following irradiation, growth to a large size, and failure to metastasize.
D000238:Adenoma, Chromophobe / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced; D010911:Pituitary Neoplasms / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D012509:Sarcoma / Q000209:etiology* / Q000473:pathology