[Experimentally induced tumors used for angiographic estimation of embolisation and cytostatic treatment (author's transl)].
In 12 rats tumors have been induced chemically by intraperitoneal application of dimethylnitrosamine. This method is simple and reliable and the effect of tumor embolisation can be followed easily. Thymus aplastic nude mice with transplanted human tumors deserve strict care. Tumor microangiograms of 48 animals demonstrate a close similarity with angiograms of corresponding human tumors. The vascular pattern does not alterate after several transplantations, after cytostatic therapy a slight hypervascularisation develops.
D000792:Angiography / Q000379:methods*; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004128:Dimethylnitrosamine / Q000633:toxicity; D004359:Drug Therapy, Combination; D004621:Embolization, Therapeutic; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000628:therapy; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging* / Q000628:therapy; D051381:Rats; D011919:Rats, Inbred Strains
D000970:Antineoplastic Agents; D004128:Dimethylnitrosamine
Experimentelle Tumoren zur angiographischen Beurteilung therapeutischer Eingriffe.