Regeneration of peripheral nerve through a polyglactin tube.
Polyglactin 910, a resorbable synthetic material, was used as a mesh-tube to bridge defects (7 to 9 mm in length) in a sectioned rabbit tibial nerve. After absorption of the mesh a new nerve sheath was formed which enclosed numerous minute fascicles of regenerating axons. The polyglactin tube influenced the direction taken by the regenerating axons and guided them into the distal segment. The tube also reduced the formation of neuromas and the growth of scar tissue from surrounding structures.
D000818:Animals; D001369:Axons / Q000502:physiology; D008866:Microsurgery / Q000295:instrumentation*; D009416:Nerve Regeneration; D010525:Peripheral Nerves / Q000033:anatomy & histology / Q000502:physiology*; D011098:Polyglactin 910; D011108:Polymers; D011817:Rabbits; D013997:Time Factors
D011108:Polymers; D011098:Polyglactin 910