Globin gene mapping in normal Hb A2 types of beta-thalassaemia.
Globin-gene mapping of DNA from 13 families with normal Hb A2 beta-thalassaemia (both type 1 and type 2) failed to detect any difference from normal in their globin-gene arrangement. We conclude that deletions such as those responsible for gamma beta-thalassaemia or a 'silent' Hb Lepore are not responsible for this type of beta-thalassaemia in Greece.
D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics; D005914:Globins / Q000235:genetics*; D006441:Hemoglobin A / Q000235:genetics*; D006443:Hemoglobin A2 / Q000235:genetics*; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D013789:Thalassemia / Q000235:genetics*
D005914:Globins; D004247:DNA; D006441:Hemoglobin A; D006443:Hemoglobin A2