Alteration of human red blood cells stored in plastic packs. A case report with in vivo and in vitro studies.
An alteration of human red blood cells while stored in certain types of plastic packs occurs to such an extent that some patients' sera are incompatible with these altered cells. This report gives details of in vivo and in vitro studies in one such case. Our results indicate a significantly shortened red blood cell survival and a marked increase in antibody titer.
D000368:Aged; D001789:Blood Group Antigens / Q000276:immunology; D001787:Blood Group Incompatibility / Q000209:etiology*; D001793:Blood Preservation / Q000009:adverse effects*; D001800:Blood Specimen Collection / Q000295:instrumentation*; D003298:Coombs Test; D004905:Erythrocyte Aging / Q000187:drug effects; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis; D008297:Male; D010968:Plasticizers / Q000009:adverse effects*; D013997:Time Factors; D065227:Transfusion Reaction
D001789:Blood Group Antigens; D007518:Isoantibodies; D010968:Plasticizers