[Psychopharmacologic approach to studying various problems in slowly progressive schizophrenia].
The therapeutic response to psychotropic drugs was analyzed in 208 patients hospitalized at the Psychiatric Clinic of the Medical Faculty of the Purkinje University (Brno, Czechoslovakia). The patients showed symptoms characteristic of borderline states. The examinations were carried out with the use of modified scale SCL-90 supplemented with 90 additional signs. It was found that the patients with slowly progressing schizophrenia responded to the psychotropic drugs in a way differing from that observed in the patients with the borderline states. It is suggested that patients with slowly progressing schizophrenia have a specific biological background of the disease that determines the type of the response.
D003866:Depressive Disorder / Q000188:drug therapy; D003937:Diagnosis, Differential; D003975:Diazepam / Q000627:therapeutic use*; D003988:Dibenzothiepins / Q000627:therapeutic use*; D004308:Dothiepin / Q000627:therapeutic use*; D006801:Humans; D008728:Methotrimeprazine / Q000627:therapeutic use*; D009440:Neurasthenia / Q000188:drug therapy; D009497:Neurotic Disorders / Q000188:drug therapy*; D012559:Schizophrenia / Q000188:drug therapy*; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000188:drug therapy*
D003988:Dibenzothiepins; D008728:Methotrimeprazine; D003975:Diazepam; D004308:Dothiepin
Psikhofarmakologicheskiĭ podkhod k izucheniiu nekotorykh voprosov malprogredientnoĭ shizofrenii.