Conformational transitions in serum high density apoproteins of hypercholesterolemic monkeys.
Conformational transitions in serum high density apolipoproteins of normal and hypercholesterolemic monkeys have been studied by circular dichroism. This study has revealed that under hypercholesterolemic conditions the secondary structure of apolipoproteins suffers permanent changes which could be observed even after a lengthy procedure of isolation, purification and delipidation of high density lipoprotein.
D000595:Amino Acid Sequence; D000818:Animals; D001053:Apolipoproteins / Q000097:blood*; D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D006863:Hydrogen-Ion Concentration; D006937:Hypercholesterolemia / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood*; D008253:Macaca mulatta; D008297:Male
D001053:Apolipoproteins; D008075:Lipoproteins, HDL