title: Human growth hormone: 1974-1981.
abstract: Chemical investigations of the human growth hormone (HGH) molecule were briefly reviewed for th period between 1974 and 1981. These include chemical modification, selective enzymic cleavage, the 20K HGH, synthetic peptide fragments, complementation of the natural NH2-terminal 134-amino acid fragment with natural or synthetic COOH-terminal fragments of various chain lengths, covalent reconstitution of two contiguous fragments of HGH with thrombin and bacterially synthesized methionyl-HGH.
mesh_terms: D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D004926:Escherichia coli / Q000378:metabolism; D013006:Growth Hormone / Q000096:biosynthesis / Q000494:pharmacology; D006801:Humans; D008970:Molecular Weight; D010446:Peptide Fragments
chemical_list: D010446:Peptide Fragments; D013006:Growth Hormone