Paradoxic hypercalcemia and hypophosphatemia associated with chronic renal failure in horses.
Chronic renal failure associated with hypercalcemia and hypophosphatemia was diagnosed in 6 horses. The renal lesions in 5 of the horses were classified as chronic glomerulonephritis and in the sixth, as chronic interstitial nephritis/pyelonephritis. There was no evidence of primary hyperparathyroidism or pseudohyperparathyroidism, thus suggesting that hypercalcemia associated with advanced renal failure in horses is related to a unique role of the equine kidney in calcium homeostasis.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005260:Female; D005921:Glomerulonephritis / Q000378:metabolism / Q000662:veterinary; D006734:Horse Diseases / Q000378:metabolism*; D006736:Horses; D006934:Hypercalcemia / Q000209:etiology / Q000378:metabolism / Q000662:veterinary*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000378:metabolism / Q000662:veterinary*; D008297:Male; D010710:Phosphates / Q000097:blood*
D010710:Phosphates; D002118:Calcium