title: How multiple sclerosis is related to animal illness, stress and diabetes.
abstract: At the University of Alberta's multiple sclerosis research clinic 100 patients with multiple sclerosis were matched to control patients for age, sex, race and zone of residence before the age of 15 years. Case and control subjects were interviewed and information was collected by questionnaire on factors that might play a role in the development of multiple sclerosis. The only factors found to be significantly associated with the development of this disorder were a history of leisure time spent in physical activities before the onset of symptoms, exposure to animal illness -- specifically canine distemper -- and a history of severe or prolonged emotional stress. The study also confirmed a familial predisposition to multiple sclerosis and suggested a relation between the disorder and a personal or family history of diabetes mellitus.
mesh_terms: D000293:Adolescent; D000328:Adult; D000416:Alberta; D000704:Analysis of Variance; D000820:Animal Diseases / Q000635:transmission*; D000818:Animals; D003625:Data Collection; D048909:Diabetes Complications; D004216:Distemper / Q000635:transmission; D004285:Dogs; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007899:Leisure Activities; D008297:Male; D009103:Multiple Sclerosis / Q000209:etiology* / Q000235:genetics; D005082:Physical Exertion; D012189:Retrospective Studies; D012306:Risk; D013315:Stress, Psychological / Q000150:complications*