Effect of electroanesthesia on local cerebral glucose utilization in the cat.
An autoradiographic method using tracer amounts of [14C]2-deoxy-D-glucose was used to detect areas of the brain in which glucose consumption was altered under extracranial electroanesthesia, as compared with ether-anesthetized cats. All brain structures studied exhibited higher glucose consumption rates than the homologous controls, by amounts varying from 14 to 174%. In 20 out of 31 structures, the increase was statistically significant. Brain structures were heterogeneous regarding the magnitude of their glucose metabolism and could be scaled accordingly; EA changed the scaling hierarchy. The periaqueductal gray (ventral part) and the red nucleus changed from moderately to highly active structures, and the cerebellar cortex became the most active of all.
D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000378:metabolism*; D001931:Brain Mapping; D002415:Cats; D003847:Deoxyglucose / Q000378:metabolism; D004580:Electronarcosis; D005947:Glucose / Q000378:metabolism*
D003847:Deoxyglucose; D005947:Glucose