Investigation of circulating immune complexes in patients with breast cancer.
Circulating immune-complex (IC) levels of patients with breast cancer were measured before and after surgery using a complement-consumption technique. 16 of 26 patients showed raised pre-operative IC values. In 15 out of 16 patients the pathological IC levels decreased within 2--10 days following surgery. Suggestions about the applicability of this test not only for prognosis, but also for monitoring the course of breast cancer need to be confirmed by further investigations.
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D003165:Complement System Proteins / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008722:Methods; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors
D000936:Antigen-Antibody Complex; D003165:Complement System Proteins