Propranolol and depression.
The authors report the cases of 3 patients who had depressive episodes after administration of propranolol for medical illnesses. The depressive episodes were severe, occurred in a dose-dependent manner, and promptly remitted when propranolol was discontinued. Physicians' awareness of this complication, especially in cases of patients with a history of depression, may reduce the occurrence of this drug reaction.
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D003866:Depressive Disorder / Q000139:chemically induced*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D011433:Propranolol / Q000008:administration & dosage / Q000009:adverse effects*
D011433:Propranolol