Use of sclera in tympanic membrane reconstruction.
Because of its high density, high tensile strength, and low antigenicity, sclera appears to be an appropriate grafting material for tympanic membrane reconstruction. I have used preserved donor sclera in 100 such cases over a three-year period with an overall success rate for complete closure of the perforation of 96%. Most of the procedures were done without hospitalization. The adults had local anesthesia; the children, general.
D000328:Adult; D002648:Child; D006085:Graft Survival; D006314:Hearing Loss, Conductive / Q000601:surgery; D006801:Humans; D009225:Myringoplasty / Q000379:methods*; D012590:Sclera / Q000637:transplantation*; D014184:Transplantation, Homologous