On the signal for activation of tubuloglomerular feedback.
nl/min), EDT fluid Osm (203 +/- vs. 235 +/- 10 mOsm/kg), distal Cl delivery (304 +/- 69 vs. 662 +/- 101 pEq/min), distal solute delivery (1186 +/- 312 vs. 2934 +/- 407 pOsm/min) and net solute reabsorption (3314 +/- 364 vs. 1566 +/- 401 pOsm/min) were significantly different. It is concluded that tubuloglomerular feedback is activated by EDT fluid chloride concentration in the region of the macula densa.
D000818:Animals; D001826:Body Fluids / Q000502:physiology; D002712:Chlorides / Q000502:physiology; D005246:Feedback; D005919:Glomerular Filtration Rate; D007678:Kidney Glomerulus / Q000502:physiology*; D007684:Kidney Tubules / Q000502:physiology*; D007686:Kidney Tubules, Distal / Q000502:physiology*; D008297:Male; D009994:Osmolar Concentration; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains
D002712:Chlorides