[Possible conformations of nucleic acid fragments containing the base pair guanine:uracil].
By using classical potential functions, nonbound interaction energy calculations are carried out on the deoxydinucleoside phosphate complexes dUpdA:dUpdG and dUpdU:dGpdA. All dihedral and bond angles, except those of the nitrogen bases, are varied. On the basis of the calculations possible conformations of nucleic acid fragments containing G:U base pair are proposed. Dihedral angles of the conformations are close to those of regular Watson-Crick helices while interaction energies are 3-4 kcal/mole higher than that of A:U containing fragment conformations.
D001482:Base Composition; D006147:Guanine; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D014498:Uracil
D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D014498:Uracil; D006147:Guanine
Vozmozhnye konformatsii uchastkov nukleinovykh kislot, soderzhashchikh paru guanin-uratsil.