title: [Pericentric inversions of chromosomes 1, 9 and 16 in patients with sex chromosome anomalies].
abstract: Studies on C-heterochromatin in chromosomes 1, 9, 16 in 83 patients with the Shereshevsky-Turner syndrome and in 23 patients with the Klinefelter syndrome revealed the highest number of inversions in chromosome 9 and no inversions in chromosome 16. The inversion frequency in chromosomes 1 and 9 did not significantly differ from the control. Complete inversions were found only in the patients with isochromosome Xq, their frequency being increased in this group. A significant rise of complete inversions in chromosome 9 was found in a group of patients with Klinefelter syndrome. A tendency to inversion concentrations in chromosome 9 under human autosome anomalies, reported in the literature, was also detected in patients with sex chromosome anomalies.
mesh_terms: D007446:Chromosome Inversion; D002900:Chromosomes, Human, 1-3 / Q000648:ultrastructure*; D002902:Chromosomes, Human, 16-18 / Q000648:ultrastructure*; D002906:Chromosomes, Human, 6-12 and X / Q000648:ultrastructure*; D005260:Female; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics*; D008297:Male; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014424:Turner Syndrome / Q000235:genetics*
chemical_list: D006570:Heterochromatin
vernacular_title: Peritsentricheskie inversii khromosom 1, 9, 16 u bol'nykh s anomaliiami polovykh khromosom.