Bicuculline blocks diazepam-induced feeding in Syrian hamsters.
Bicuculline antagonizes diazepam induced feeding in Syrian hamsters in a dose dependent manner using doses which do not affect running wheel activity. These results suggest that diazepam-induced feeding can be completely and specifically blocked by antagonizing GABA.
D000818:Animals; D001640:Bicuculline / Q000494:pharmacology*; D006224:Cricetinae; D003975:Diazepam / Q000037:antagonists & inhibitors*; D005247:Feeding Behavior / Q000187:drug effects*; D008297:Male; D008647:Mesocricetus; D009043:Motor Activity / Q000187:drug effects
D003975:Diazepam; D001640:Bicuculline