title: Circadian timing of sleepiness in man and woman.
abstract: Men and women living contentedly in long-term isolation from the usual time-of-day cues have revealed surprising new regularities about the timing of human sleep/wake alternations. Contemporary effort to ferret out and articulate these regularities in quantitative terms lead to a diversity of mathematical models. If these eventually acquire predictive competence then we may expect practical improvements of therapy for insomnia, jet lag, and some kinds of psychiatric depression.
mesh_terms: D001831:Body Temperature; D002490:Central Nervous System / Q000502:physiology; D002940:Circadian Rhythm; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000378:metabolism; D008954:Models, Biological; D010775:Photic Stimulation; D012890:Sleep / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000150:complications; D013997:Time Factors; D014851:Wakefulness
chemical_list: D008550:Melatonin