Structural polypeptides of molluscum contagiosum virus: their variability in various isolates and location within the virion.
The structural polypeptides of molluscum contagiosum virus (MCV) obtained from the skin lesions of patients were examined by SDS-polyacrylamide gel electrophoresis. At least 40 polypedtides from purified virions were detected on SDS-polyacrylamide gel by a highly sensitive silver stain. Two of the structural polypeptides of the nine isolates were different in their migration rate in SDS-polyacrylamide gel. Following controlled degradation virions the two variable polypeptides were shown to be located in the surface or subsurface layers.
D002648:Child; D002675:Child, Preschool; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D008297:Male; D008623:Mercaptoethanol / Q000494:pharmacology; D008854:Microscopy, Electron; D008977:Molluscum contagiosum virus / Q000032:analysis*; D010455:Peptides / Q000032:analysis; D013501:Surface-Active Agents; D014764:Viral Proteins / Q000032:analysis*
D010455:Peptides; D013501:Surface-Active Agents; D014764:Viral Proteins; D008623:Mercaptoethanol