title: Amino acid substitutions far from the active site of bacteriophage T4 lysozyme reduce catalytic activity and suggest that the C-terminal lobe of the enzyme participates in substrate binding.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001665:Binding Sites; D004355:Drug Stability; D007700:Kinetics; D008958:Models, Molecular; D009113:Muramidase / Q000235:genetics* / Q000378:metabolism; D009154:Mutation; D011487:Protein Conformation; D013604:T-Phages / Q000201:enzymology* / Q000235:genetics; D014961:X-Ray Diffraction
chemical_list: D000596:Amino Acids; D009113:Muramidase