title: Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia.
abstract: In toad and frog urinary bladder, electrophysiological data suggest that inhibition of transepithelial sodium transport by mucosal amiloride results in a decrease in basolateral membrane conductance. These results were confirmed by showing that amiloride addition caused a decrease in basolateral membrane potassium permeability.
mesh_terms: D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D001693:Biological Transport, Active / Q000187:drug effects; D004848:Epithelium / Q000187:drug effects*; D008564:Membrane Potentials / Q000187:drug effects; D011188:Potassium / Q000502:physiology*; D011719:Pyrazines / Q000494:pharmacology*; D012964:Sodium / Q000502:physiology*; D001743:Urinary Bladder
chemical_list: D011719:Pyrazines; D000584:Amiloride; D012964:Sodium; D011188:Potassium