Queuine, a modified base incorporated posttranscriptionally into eukaryotic transfer RNA: wide distribution in nature.
Queuine, a modified base found in transfer RNA, appears to be a new dietary factor because (i) previous studies have shown that mice require it for the expression of queuine-containing transfer RNA's but apparently do not synthesize it, and (ii) significant amounts of free queuine are present in common plant and animal food products.
D000818:Animals; D004032:Diet; D005057:Eukaryotic Cells / Q000378:metabolism; D005856:Germ-Free Life; D006147:Guanine / Q000031:analogs & derivatives* / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism*
D006147:Guanine; C019549:queuine; D012343:RNA, Transfer