An intravasal non-occlusive contraceptive device in rats.
An implantable miniature biogalvanic cell was developed to kill the spermatozoa in the vas deferens by an electric current. Experiments in vitro and in vivo showed that a combination of aluminum/silver electrodes connected with platinum wires with the vas deferens fluid as n electrolyte is effective in killing spermatozoa. Female rats paired with males having biogalvanic devices in the vas deferens, which remained patent, did not produce any young.
D000535:Aluminum; D000818:Animals; D001674:Bioelectric Energy Sources; D003275:Contraceptive Devices, Male; D004567:Electrodes, Implanted; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012834:Silver; D013094:Spermatozoa; D013997:Time Factors; D014649:Vas Deferens
D012834:Silver; D000535:Aluminum