title: Androgen levels in the lipid of the canine vas deferens and peripheral plasma.
abstract: Radioimmunoassays were used for the measurement of several androgens in canine plasma and in the liquid of the vas deferens. Large variations in the plasma concentrations of androstenedione, testosterone and 5 alpha-dihydrotestosterone occurred during a period of 24 h, but there was no evidence of a circadian rhythm. The ratios of the androgen concentration in the liquid of the vas deferens compared with that in the peripheral plasma were: androstenedione, 4.6; testosterone, 1.9; 5 alpha-dihydrotestosterone, 13.6; 5 alpha-androstane-3 alpha, 17 beta-diol, 17.0; 5 alpha-diol, 22.4. These high levels of androgens in the liquid of the vas deferens could play a role in the development of prostatic hypertrophy.
mesh_terms: D000728:Androgens / Q000097:blood / Q000378:metabolism*; D000735:Androstenedione / Q000378:metabolism; D000818:Animals; D013196:Dihydrotestosterone / Q000378:metabolism; D004285:Dogs; D008297:Male; D011863:Radioimmunoassay; D013739:Testosterone / Q000378:metabolism; D014649:Vas Deferens / Q000378:metabolism*
chemical_list: D000728:Androgens; D013196:Dihydrotestosterone; D013739:Testosterone; D000735:Androstenedione