Electrocochleographic study of Ménière's disease.
Auditory nerve action potential (AP), cochlear microphonics (CM), and summating potential (SP) were recorded from 32 patients with Ménière's disease. Patients were classified into three groups according to the degree of their hearing impairment. The group of patients that had a mild to moderate hearing loss and whose hearing was reversible showed notably satisfactory responses for AP, CM, and negative SP (-SP), and also showed a high incidence of positive SP (+SP). Low responses for AP and CM with an increase of detection thresholds and a high -SP/AP ratio were obtained from patients with moderate hearing impairment, whose hearing fluctuated slightly. These electrocochleographic findings were suggestive of the pathophysiologic differences at the various stages of Ménière's disease.
D001300:Audiometry, Evoked Response; D001309:Auditory Threshold; D003055:Cochlear Microphonic Potentials; D005072:Evoked Potentials, Auditory; D006198:Hair Cells, Auditory / Q000503:physiopathology; D034381:Hearing Loss / Q000503:physiopathology; D006801:Humans; D008575:Meniere Disease / Q000503:physiopathology*; D011930:Reaction Time; D000159:Vestibulocochlear Nerve / Q000503:physiopathology