title: Induction of labour: a comparison of a single prostaglandin E2 vaginal tablet with amniotomy and intravenous oxytocin.
abstract: In a randomized controlled study of 100 women of low parity and favourable induction features, induction of labour by means of a single vaginal tablet containing 3 mg of prostaglandin E2 (PGE2) was compared with the conventional method of amniotomy and intravenous oxytocin. Four of the patients (8%) who received the prostaglandin tablet required additional intravenous oxytocin to achieve delivery. The prostaglandin group had a longer mean overall induction-delivery interval but a shorter amniotomy-delivery interval than the oxytocin group. One patient in the PGE2 group and two in the oxytocin group required caesarean section. The PGE2 treated patients expressed a higher level of satisfaction with their method of induction, they required less analgesia, had less blood loss at delivery and their babies had a lower incidence of neonatal jaundice.
mesh_terms: D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D015232:Dinoprostone; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007751:Labor, Induced / Q000379:methods*; D010121:Oxytocin / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage / Q000627:therapeutic use*; D011897:Random Allocation; D013607:Tablets; D014621:Vagina
chemical_list: D011458:Prostaglandins E; D013607:Tablets; D010121:Oxytocin; D015232:Dinoprostone