title: The clinical significance of large lymphoid follicles of the colon.
abstract: In 17 patients, large colonic lymphoid follicles were visible on air-contrast barium-enema examination (ACBE). They varied in size but were at least 4 mm in diameter and located predominantly in the rectosigmoid region. Inflammatory bowel disease was found in 13 patients (73%) and lymphoma in 1. In 100 controls without signs or symptoms of inflammatory bowel disease, the lymphoid follicles did not exceed 3 mm; they were visible radiographically in 52% of patients under 30 and 17% of those over 30. Lymphoid follicles which measure greater than or equal to 4 mm on ACBE should suggest inflammatory bowel disease or, less likely, lymphoma or dysgammaglobulinemia.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000388:Air; D001466:Barium Sulfate; D002648:Child; D003093:Colitis, Ulcerative / Q000000981:diagnostic imaging; D003106:Colon / Q000000981:diagnostic imaging*; D003108:Colonic Diseases / Q000000981:diagnostic imaging*; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging; D003424:Crohn Disease / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008221:Lymphoid Tissue / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography
chemical_list: D001466:Barium Sulfate