title: [Iodine-induced hyperthyroidism in the aged. 2. Pathomechanism, differential diagnosis and therapy problems].
abstract: The occurrence of multiple processes in elderly patients brings a high risk for diagnostic or therapeutic induced iodine-hyperthyroidism. Often an atypical form of hyperthyroidism without classical symptoms is induced. The cause of iodine-induced hyperthyroidism exists mostly in autonomous tissue beyond a "critical volume" in localized or disseminated form. If the deficiency of iodine in endemic goitre areas is substituted by iodine-application, hypermetabolism of autonomous tissue causes hyperthyroidism. The pathomechanism of autonomy and iodine-induced hyperthyroidism is not completely known. General iodine salt prophylaxis will bring less amounts of autonomous goitres. Some differential diagnostic possibilities for avoiding iodine-contamination in the elderly patients and therapeutic consequences after unavoidable iodine-application are described.
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006042:Goiter / Q000188:drug therapy; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000532:radiotherapy; D007455:Iodine / Q000009:adverse effects* / Q000172:deficiency / Q000627:therapeutic use; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D011379:Prognosis
chemical_list: D007457:Iodine Radioisotopes; D007455:Iodine
vernacular_title: Jod-induzierte Hyperthyreose im Alter. Teil 2: Pathomechanismus, differentialdiagnostische und therapeutische Probleme.