Vitamin E does not modify HDL-cholesterol.
Vitamin E has been reported to increase serum high-density lipoprotein (HDL) cholesterol. Given the known inverse relationship between HDL-cholesterol and risk of developing coronary artery disease, these preliminary results require verification or refutation. In the present study, 39 volunteers were given 600 U of vitamin E daily for 30 days. Serum vitamin E, cholesterol, HDL-cholesterol, and triglycerides were measured at appropriate intervals. No significant change in serum HDL-cholesterol with vitamin E therapy could be documented.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D014810:Vitamin E / Q000097:blood / Q000494:pharmacology*
D008076:Cholesterol, HDL; D008075:Lipoproteins, HDL; D014280:Triglycerides; D014810:Vitamin E; D002784:Cholesterol