Cytogenetic effects of epoxy, phenolformaldehyde and polyvinylchloride resins in man.
The cytogenetic analysis of persons occupationally exposed to synthetic resins has revealed a true increase in the average frequency of cells with chromosome aberrations: 5.5% for epoxy resin (146 persons), 6.1% for polyvinylchloride (52 persons), and 5.0% for phenolformaldehyde (31 persons). An incidence of 2.4% was observed in the control (74 persons). The average frequency of aberrant chromosomes per cell for all the synthetic resins (0.054-0.065) differed from the control. The average frequency of chromosome breaks per chromosome did not differ significantly from the control. Acentric fragments (single and paired) was the prevalent type of aberration.
D002478:Cells, Cultured; D002869:Chromosome Aberrations; D004781:Environmental Exposure; D004853:Epoxy Resins / Q000494:pharmacology; D005557:Formaldehyde / Q000494:pharmacology; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D009153:Mutagens; D009787:Occupational Medicine; D010636:Phenols / Q000494:pharmacology; D011108:Polymers; D011143:Polyvinyl Chloride / Q000494:pharmacology; D012117:Resins, Synthetic / Q000494:pharmacology*
D004853:Epoxy Resins; D009153:Mutagens; D010636:Phenols; D011108:Polymers; D012117:Resins, Synthetic; D005557:Formaldehyde; D011143:Polyvinyl Chloride; C011529:phenol-formaldehyde resin