title: Renal function of the pony and the horse.
abstract: Simultaneous renal clearances of inulin (CIN), p-aminohippurate (CPAH), and creatinine (CCR) were measured in hydrated mares (6 ponies and 2 horses). The CIN and CPAH were determined during steady-state infusion at 3 different infusion rates. A 6-fold change in plasma IN concentration did not produce alteration in CIN, nor was there a difference between the ponies and horses (P greater than 0.2). The overall average (mean +/- SEM) was 190.6 +/- 5.89 ml . min-1 . 100 kg of body weight-1. There was no difference noted between simultaneous CIN and CPAH. Clearance of PAH remained essentially constant during the change in plasma PAH from 0.33 mg/dl to 5.27 mg/dl. The extraction ratio of PAH for the nonanesthetized pony was 0.966. Effective renal plasma flow (CPAH) of the pony exceeded that of the horse.
mesh_terms: D000618:Aminohippuric Acids / Q000378:metabolism*; D000818:Animals; D003404:Creatinine / Q000097:blood / Q000378:metabolism* / Q000652:urine; D005260:Female; D006736:Horses / Q000502:physiology*; D007444:Inulin / Q000097:blood / Q000378:metabolism* / Q000652:urine; D007668:Kidney / Q000502:physiology*; D010130:p-Aminohippuric Acid / Q000097:blood / Q000378:metabolism* / Q000652:urine
chemical_list: D000618:Aminohippuric Acids; D007444:Inulin; D003404:Creatinine; D010130:p-Aminohippuric Acid