Kinetics of the spread of the Yoshida ascites hepatoma cancer cells through various organs of the rat.
In the present paper the attempt is pursued to provide a self-consistent interpretation for the quantitative measurements of the amount of neoplastic cells found at different anatomic sites and at various times after intraperitoneal injection. The model, employing a system of 8 linear differential equations with constant coefficients, can be fitted by means of a special program for a small processing system equipped with an 8-bit microprocessor and 48 KB of central memory.
D000818:Animals; D004195:Disease Models, Animal; D007700:Kinetics; D008114:Liver Neoplasms, Experimental / Q000473:pathology*; D008433:Mathematics; D009362:Neoplasm Metastasis / Q000473:pathology*; D051381:Rats; D012517:Sarcoma, Yoshida / Q000473:pathology*