title: [Age-related characteristics of the state of the hypophyseal-gonad-adrenal system in rabbits].
abstract: The time-course of changes in testicular and adrenal secretion as well as hypophyseal gonadotropic activity was studied in experimental rabbits during sexual maturity, maximum sex gland functioning at the advanced reproductive period and in the aged animals with lowered gonadal activity. It was shown that activation of testosterone an androstenedione testicular secretion in the mature animals at the reproductive period is replaced by a sharp inhibition of testicular androgenopoiesis in the aged animals. At the same time adrenal testosterone production remains stable over the whole life. The hypophyseal gonadotrophin level negatively correlates with testicular androgen production, but does not depend on adrenal androgen secretion.
mesh_terms: D000375:Aging; D000728:Androgens / Q000378:metabolism; D000735:Androstenedione / Q000097:blood; D000818:Animals; D006065:Gonadotropins, Pituitary / Q000032:analysis; D008297:Male; D009929:Organ Size; D010913:Pituitary-Adrenal System / Q000378:metabolism*; D011817:Rabbits; D013737:Testis / Q000378:metabolism*
chemical_list: D000728:Androgens; D006065:Gonadotropins, Pituitary; D000735:Androstenedione
vernacular_title: Vozrastnye osobennosti sostoianiia gipobizarno-gonadno-nadpochechnikovoĭ sistemy u krolikov.