title: [Acute lung embolism: pathophysiology, clinical aspects and therapy].
abstract: Cautious estimates reveal that the diagnosis of pulmonary embolism is missed in approximately 60-70% of cases. The outcome in these patients is poor, mainly due to a tendency to relapsing embolism. Knowledge of pathophysiological contexts is important for clinical diagnosis and for evaluating degree of embolism. In most cases consistent conservative treatment is sufficient. Emergency embolectomy is indicated in cases with severe central pulmonary embolism. Operation mortality has dropped considerably since the introduction of cardiopulmonary bypass.
mesh_terms: D001920:Bradykinin / Q000502:physiology; D004417:Dyspnea / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D008168:Lung / Q000000981:diagnostic imaging; D011379:Prognosis; D011655:Pulmonary Embolism / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D011859:Radiography; D013300:Streptokinase / Q000627:therapeutic use; D013924:Thrombophlebitis / Q000150:complications; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator; D001920:Bradykinin
vernacular_title: Akute Lungenembolien: Pathophysiologie, Klinik und Therapie.