Rebound gentamicin levels after hemodialysis.
After observing the phenomenon clinically, seven post-hemodialysis patients were studied for a rebound effect of gentamicin levels. Serum gentamicin levels were obtained immediately after dialysis and 1 hr postdialysis. An average 25.7% rebound occurred in the serum levels. A slow redistribution of gentamicin out of tissue into the serum is the probable mechanism. This data suggests that a short time period should be allowed before postdialysis levels are obtained to determine gentamicin replacement doses.
D058186:Acute Kidney Injury / Q000097:blood; D000328:Adult; D005260:Female; D005839:Gentamicins / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
D005839:Gentamicins