Long-term follow-up of children born after amniocentesis.
Paediatric and neurodevelopmental examinations were made of 122 children between the ages of 5 and 7 years. The mothers of 62 of these children had undergone amniocentesis for prenatal chromosome determination. The other 60 children were controls, matched for time of birth and maternal age. The fact that no difference between the groups was revealed in respect of paediatric and neurodevelopmental disorders, orthopaedic abnormalities, or respiratory problems during the neonatal period indicates that the risk for developmental complications is not increased in children born after amniocentesis in the second trimester.
D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D002648:Child; D002657:Child Development; D005260:Female; D005500:Follow-Up Studies; D006128:Growth; D006801:Humans; D008297:Male; D008423:Maternal Age; D011247:Pregnancy; D012306:Risk; D013997:Time Factors