Evidence against an abstraction or direct insertion mechanism for cytochrome P-450 catalysed meta hydroxylations.
D000818:Animals; D001571:Benzoflavones / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003903:Deuterium; D006900:Hydroxylation; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D014859:Warfarin / Q000378:metabolism*; D019324:beta-Naphthoflavone
D001571:Benzoflavones; D014859:Warfarin; D019324:beta-Naphthoflavone; D003577:Cytochrome P-450 Enzyme System; D003903:Deuterium; D010634:Phenobarbital