title: Tray drying of pharmaceutical wet granulations.
abstract: It is shown that in tray drying wet granulated materials, the expected log-linear plots give slopes that are inversely proportional to the bed depth, rather than to the depth squared. A model is proposed for this giving diffusion coefficients of the order of magnitude expected fro liquid-water diffusion. The temperature dependence also suggests that this is the rate-limiting process rather than vapor diffusion.
mesh_terms: D003890:Desiccation; D007700:Kinetics; D008956:Models, Chemical; D011208:Powders; D013678:Technology, Pharmaceutical
chemical_list: D011208:Powders