title: Reassessment of the human chorionic gonadotropin stimulation test in hypogonadal males.
abstract: Eight normal and 17 hypogonadal males were injected with human chorionic gonadotropin (hCG). In normal males at 48 hr testosterone and estradiol became, respectively, 160% and 338% of basal values. In hypogonadal males at 48 hr testosterone and estradiol became respectively, 211% and 127% of basal values. No changes occurred in serum thyroid stimulating hormone (TSH), serum thyroxine (T4), and tri-iodothyronine (T3). The success of long-term therapy with hCG in five patients was predicted by the test.
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D013196:Dihydrotestosterone / Q000097:blood; D004958:Estradiol / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007006:Hypogonadism / Q000097:blood* / Q000188:drug therapy; D008297:Male; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D006063:Chorionic Gonadotropin; D012739:Gonadal Steroid Hormones; D014284:Triiodothyronine; D013196:Dihydrotestosterone; D013739:Testosterone; D004958:Estradiol; D013972:Thyrotropin; D013974:Thyroxine