Different responses of rat endometrial epithelium and stroma to induction of oestradiol binding sites by progesterone.
Rats were ovariectomized for 3 weeks and then treated for 3 days with 4 mg progesterone. The cytosolic oestradiol receptor content in the stroma cells was very high (approximately 21,000 binding sites/cell) as compared with that in the epithelial cells (approximately 3000 binding sites/cell). The nuclear receptor values were low (approximately 500 binding sites/cell) in both types of cell.
D000818:Animals; D002369:Castration; D002467:Cell Nucleus / Q000032:analysis; D003600:Cytosol / Q000032:analysis; D004717:Endometrium / Q000032:analysis / Q000187:drug effects*; D004848:Epithelium / Q000032:analysis; D004958:Estradiol; D005260:Female; D011374:Progesterone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000032:analysis / Q000187:drug effects*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011374:Progesterone; D004958:Estradiol