title: Neurons in the rat dentate gyrus granular layer substantially increase during juvenile and adult life.
abstract: Volumetric estimates of the total number of granule cells in rats 30, 120, 200, and 365 days old increase linearly by approximately 35 to 43 percent between 1 month and 1 year. Total volume of the granular layer also grows linearly during that time. These results demonstrate a numerical increase in a neuronal population during adulthood in the mammalian brain.
mesh_terms: D000367:Age Factors; D000818:Animals; D006624:Hippocampus / Q000166:cytology / Q000254:growth & development*; D008297:Male; D051381:Rats