Gallstone dissolution using mono-octanoin infusion through an endoscopically placed nasobiliary catheter.
Endoscopic sphincterotomy is widely being used for the treatment of common bile duct stones. In a small group of patients the gallstones are large in size and, hence, difficult to be extracted after a successful endoscopic sphincterotomy. We used a constant infusion of mono-octanoin through a nasobiliary catheter in nine such patients. This method was successful in partial or complete dissolution of the stones in 74% of the patients. In the remaining 36% of the patients, the stones were noted to be soft allowing easy extraction by crushing.
D002210:Caprylates; D002404:Catheterization; D004724:Endoscopy; D042882:Gallstones / Q000188:drug therapy*; D005989:Glycerides / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007263:Infusions, Parenteral; D012995:Solubility
D002210:Caprylates; D005989:Glycerides; C025343:monooctanoin