Absence of a direct chronotropic effect of vasopressin on the myocardial cell.
The direct effect of arginine vasopressin on the rat myocardial cell automaticity was examined in tissue culture. No significant changes in contraction frequency were observed at concentrations ranging from 10 microunits to 10 milliunits/ml vasopressin in culture medium.
D000818:Animals; D000831:Animals, Newborn; D001127:Arginine Vasopressin / Q000494:pharmacology; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D051381:Rats; D014667:Vasopressins / Q000494:pharmacology*
D014667:Vasopressins; D001127:Arginine Vasopressin