Local regulation of blood flow and the occurrence of edema after arterial reconstruction of the lower limbs.
The relation between edema after arterial reconstruction of the lower limbs and various potential etiologic factors, including disturbances in local blood flow regulating mechanisms, was investigated in 22 patients with occlusive arterial disease. The occurrence of edema was unrelated to the severity of symptoms as well as to the perioperative changes in distal arterial blood pressure. Postreconstructive edema developed independently of postreconstructive hyperemia and of disturbances in the local vasoconstrictor response to increased venous pressure. The decisive factor for development of edema was the extensive dissection in the thigh and in the popliteal region required for femoropopliteal bypass surgery. Edema developed after nine of nine femoropopliteal bypass operations, and only after one of 12 reconstructions in the aorto-iliac or in the profound femoral segments (p = 0.001). It is concluded that the postreconstructive edema is a lymphedema due to surgical trauma, rather than the result of microvascular derangement.
D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D005260:Female; D005263:Femoral Artery; D005528:Foot / Q000098:blood supply; D006801:Humans; D006940:Hyperemia / Q000209:etiology; D007866:Leg / Q000098:blood supply*; D008209:Lymphedema / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery; D011183:Postoperative Complications; D012039:Regional Blood Flow; D014661:Vasoconstriction