[Relationship of insulin-stimulated ATP formation to insulin action on creatine accumulation in plasma membrane-enriched particles of rat skeletal muscles].
ATP accumulated in the enriched with cytoplasmic membranes particles, isolated from rat skeletal muscles, after incubation of the particles in the medium containing insulin. After boiling in a water-bath of the particulate fraction supernatants, incubated in the presence of insulin, total content of creatine was increased in the particles and the content of 1-14C creatine in the medium was decreased.
D000042:Absorption; D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D003401:Creatine / Q000378:metabolism*; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D009132:Muscles / Q000187:drug effects* / Q000378:metabolism; D051381:Rats
D007328:Insulin; D000255:Adenosine Triphosphate; D003401:Creatine
Sviaz' stimuliruemogo insulinom obrazovaniia ATF s deistviem insulina na nakoplenie kreatina v obogashchennykh plazmaticheskimi membranami chastitsakh iz skeletnykh myshts krysy.