Conversion of the prosthetic moieties of glutathione pathway conjugates to the corresponding S-acetates.
A simple acetylation procedure was shown to from S-acetates of the xenobiotic moieties of mercapturic acid pathway metabolites. The S-acetates that were produced were characterized by mass spectrometry or by gas chromatography mass spectrometry.
D000107:Acetylation; D000111:Acetylcysteine / Q000032:analysis* / Q000378:metabolism; D000818:Animals; D001646:Bile / Q000032:analysis / Q000378:metabolism; D005243:Feces / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D005978:Glutathione / Q000378:metabolism*; D051381:Rats
D005978:Glutathione; D000111:Acetylcysteine