title: [The effects of metoprolol on systolic times in patients with systemic arterial hypertension. Polygraphic study].
abstract: 10 patients with systemic essential arterial hypertension have been treated with 200 mg/die of Metoprolol. The systolic times have been valued before and after the treatment. It has been observed a reduction of the pre-ejection period simultaneously and proportionally to the reduction of the arterial pressure and the cardiac frequence. These last parameters and the indices of consumption of oxygen and heart frequence have undergone a significant decrease since the first week of therapy. The bloodless indices which express the myocardic contractility demonstrated instead not to be particularly influenced.
mesh_terms: D000328:Adult; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use*; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D011412:Propanolamines / Q000627:therapeutic use*; D013599:Systole / Q000187:drug effects*
chemical_list: D011412:Propanolamines; D008790:Metoprolol
vernacular_title: Effetti del metoprololo sui tempi sistolici di soggetti con ipertensione arteriosa sistemica. Studio poligrafico.