[The HbA1c-determination with the aid of isoelectrofocusing method in the out patient control of juvenile diabetics (author's transl)].
In juvenile diabetics treated on an outpatient basis, the HbA1c value was determined by means of isoelectric focusing. This method proved to be relatively simple and reproducible. Approximately 24 samples can be examined simultaneously after capillary withdrawal. The following correlations were found: 1. with the average urinary glucose excretion - a) measured by the clinitest method, measurement being effected several times daily over a period of 4 weeks (R = 0.5063), as well as b) with the 24-hour urinary glucose excretion of the day of withdrawal, 4 weeks, 8 weeks and 12 weeks previously. Best agreement was found between the HbA1c value and the sum of urinary glucose excretion on the day of withdrawal, 4 weeks and 8 weeks previously (correlation coefficient R = 0.6022). 2. a relationship was also found in the current blood sugar levels (correlation coefficient R = 0.5061). The results are discussed with regard to the significance of the HbA1c measurement.
D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D006029:Glycosuria / Q000276:immunology; D006441:Hemoglobin A / Q000032:analysis*; D006801:Humans; D007525:Isoelectric Focusing
D001786:Blood Glucose; D006441:Hemoglobin A
Die HbA1c-Bestimmung mit der Methode der Isoelektrofokussierung in der ambulanten Uberwachung juveniler Diabetiker.