title: The significance of luminance on visual evoked potentials in diagnosis of MS.
abstract: In view of the fact that with psychophysical methods monocular luminance changes may increase the detection rate of pathological interocular-latency differences in MS patients, we studied the influence of stimulus luminance on the detection rate of MS using checkerboard visual evoked potentials. Decrements of stimulus luminance covering a range of three log units were unable to increase the detection rate of VEP. Regression coefficients of the luminance-latency functions did not differ in MS patients and normals. Contrary to the hypothesis tested, the diagnostic significance of VEP decreases with decreasing stimulus intensity.
mesh_terms: D000328:Adult; D004292:Dominance, Cerebral; D005074:Evoked Potentials, Visual; D006801:Humans; D008027:Light; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000523:psychology