A comparative in vitro study of thienamycin.
The in vitro activity of thienamycin was compared to that of other antibiotics against a large panel of bacteria obtained in blood cultures from cancer patients. This compound was the most active against gram-positive cocci and also proved to be extremely active against the gram-negative bacteria. It was also very active against multi-resistant gram-negative bacilli. Because of its broad spectrum of activity including Pseudomonas spp., thienamycin deserves clinical testing in the future.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004755:Enterobacteriaceae / Q000187:drug effects; D007769:Lactams / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013845:Thienamycins
D000900:Anti-Bacterial Agents; D007769:Lactams; D013845:Thienamycins; C015537:thienamycin