title: Relapse of Paragonimus westermani lung infection after bithionol therapy.
abstract: Clinical trials of bithionol in treating Paragonimus westermani lung infection have been conducted in areas of endemic infection. Bithionol has been reported to cure over 90% of infected patients. We report a case of a 32-year-old Laotian man residing in Connecticut who relapsed with P. westermani pneumonitis 4 months after apparent eradication of infection with bithionol (40 mg/kg by mouth every other day for 10 doses). He was successfully treated with a second course of bithionol (40 mg/kg by mouth every other day for 15 doses). The mechanism of relapse of P. westermani infection following bithionol therapy should be evaluated.
mesh_terms: D000328:Adult; D001735:Bithionol / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008174:Lung Diseases, Parasitic / Q000188:drug therapy*; D008297:Male; D010237:Paragonimiasis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D010636:Phenols / Q000627:therapeutic use*; D011859:Radiography; D012008:Recurrence
chemical_list: D010636:Phenols; D001735:Bithionol