Age differences in blood pressure and norepinephrine concentration in normotensive rats after higher doses of estrogen.
1. Normotensive rats (3 months old) showed 6-9% increases in blood pressure (B.P.) after high doses of estrogen, with increases in hypothalamic and adrenal norepinephrine (NE). 2. Older normotensive rats (6 months old) showed 4-11% increases in B.P. after high doses of estrogen with a decrease in brainstem NE.
D000311:Adrenal Glands / Q000378:metabolism; D000375:Aging; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000378:metabolism; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D008656:Mestranol / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D004967:Estrogens; D008656:Mestranol; D009638:Norepinephrine