A transient deficit in neutrophilic chemotaxis in a dog with recurrent staphylococcal pyoderma.
A transient neutrophilic chemotactic deficit was confirmed in a 3 1/2-year-old castrated male dog with recurrent staphylococcal pyoderma accompanied by a persistent eosinophilia and intermittent basophilia. Neutrophilic chemotaxis was quantitatively assessed over the next seven months, and the disappearance of the chemotactic deficit correlated with complete clinical remission of the skin lesions. Aberrations of the complement system were not discovered, and the dog's serum showed increased chemoattractiveness for control neutrophil preparations.
D000818:Animals; D001681:Biological Assay; D002634:Chemotaxis, Leukocyte / Q000187:drug effects; D004283:Dog Diseases / Q000276:immunology / Q000503:physiopathology*; D004285:Dogs; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D009504:Neutrophils / Q000502:physiology*; D011711:Pyoderma / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*; D012008:Recurrence; D013203:Staphylococcal Infections / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*
D007136:Immunoglobulins