title: Fly ash lung: a new pneumoconiosis?
abstract: A laborer who worked in a steel mill and in a shipyard developed a nonspecific pulmonary interstitial fibrosis. Postmortem samples of his lung were digested, and the inorganic material present was extracted and examined using transmission electron microscopy, electron diffraction, and electron microprobe analysis. Uncoated asbestos fibers were present (1.4 X 10(5)/g wet lung), but the surprising finding was the presence of a large number of fly ash particles (6 X 10(6)/g wet lung). Fly ash, the particulate material produced during coal combustion, has not previously been reported to be present in human lung tissue. Although the contribution of the asbestos to this man's lung disease is uncertain, we believe, based on previous studies implicating aluminum silicates in pneumoconiosis, that the fly ash, an aluminum silicate, may be a contributing factor.
mesh_terms: D000368:Aged; D002244:Carbon / Q000009:adverse effects*; D003031:Coal; D060729:Coal Ash; D004391:Dust; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008669:Metallurgy; D052638:Particulate Matter; D011009:Pneumoconiosis / Q000209:etiology* / Q000473:pathology
chemical_list: D003031:Coal; D060729:Coal Ash; D004391:Dust; D052638:Particulate Matter; D002244:Carbon