Effect of pindolol and propranolol on renal function of patients with hypertension.
1 Pindolol and propranolol were administered orally in equipotent antihypertensive doses to 14 subjects with mild to moderate hypertension in an open cross-over study. 2 Pindolol caused a smaller decrease in plasma renin activity and heart rate than propranolol. 3 Glomerular filtration rate and effective renal plasma flow remained unchanged during therapy with either agent.
D000328:Adult; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007674:Kidney Diseases / Q000139:chemically induced*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000009:adverse effects* / Q000627:therapeutic use; D011433:Propranolol / Q000009:adverse effects* / Q000627:therapeutic use; D012079:Renal Circulation / Q000187:drug effects; D013997:Time Factors
D011433:Propranolol; D010869:Pindolol