Haemolytic transfusion reaction due to ABO incompatible plasma in a platelet concentrate.
A patients of blood type A1 developed brisk, but transient haemolysis after receiving a platelet transfusion derived from 4 group 0 donors. Anti-A was detected on his red cells and in his plasma. 2 of the platelet donor were found to have very high titers (1:10240) of anti-A and positive haemolysin tests. Thus, a haemolytic reaction can result from transfusion of incompatible plasma in a platelet concentrate.
D001789:Blood Group Antigens / Q000276:immunology*; D001787:Blood Group Incompatibility; D001803:Blood Transfusion; D003298:Coombs Test; D006460:Hemolysin Proteins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D017713:Platelet Transfusion
D001789:Blood Group Antigens; D006460:Hemolysin Proteins