Separation and spread of nuclear fragments ("nucleotesimals") in colonic neoplasms.
After multiple fragmentation of neoplastic nuclei into "nucleotesimals," a recently discovered variety of amitosis, some fragments appear to be inflated to full nuclear size; other probably lyse, releasing nucleic acid, which may assist in the synthesis of new cytoplasm around newly formed nuclei. This observation may be useful in elucidating one mechanism of neoplastic growth.
D002455:Cell Division; D002467:Cell Nucleus / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology*; D006801:Humans