Evaluation of bone marrow granulocyte reserves in neutropenic and nonneutropenic Yemenite Jews.
The bone marrow granulocyte reserves of 10 Yemenite Jews with hereditary neutropenia were estimated by measuring the maximum peripheral blood granulocyte increment after the administration of 40 mg prednisone. The control group consisted of 11 nonneutropenic Yemenites and 15 non-Yemenite Jews with normal peripheral blood neutrophil counts. The mean peripheral blood granulocyte increment in the neutropenic and nonneutropenic Yemenites was significantly less than in the non-Yemenite Jews. There was no significant difference in the response of the two Yemenite groups.
D000328:Adult; D000368:Aged; D000380:Agranulocytosis / Q000097:blood*; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D005260:Female; D006098:Granulocytes; D006801:Humans; D007585:Jews; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000494:pharmacology; D044469:Racial Groups; D015006:Yemen
D011241:Prednisone