[Effect of gamma therapy on liver function in the combined treatment of cancer of the cardia and esophagus].
The effects of preoperative gamma-therapy and gastrostomy performed in Dobromyslov-Torek's operation on the function of the liver were studied by histological and histochemical examination of material obtained in biopsy of liver and biochemical assays of blood in a study group including 40 patients with cardial cancer and 9 cases of esophageal tumor. It was shown that both preoperative irradiation and gastrostomy-mediated nutrition cause pronounced morphological lesions of liver tissue. Although biochemical indices remain within norm, the compensatory capability of liver in such patients is lower than in unexposed ones.
D000328:Adult; D000368:Aged; D001706:Biopsy; D002299:Cardia; D004938:Esophageal Neoplasms / Q000503:physiopathology / Q000628:therapy*; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008099:Liver / Q000503:physiopathology / Q000528:radiation effects*; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D013274:Stomach Neoplasms / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
Vliianie gamma-terapii na funktsional'noe sostoianie pecheni pri kombinirovannom lechenii bol'nykh rakom kardii i pishchevoda.