Midtrimester intrauterine exchange transfusion of the fetus.
Thirty-seven fetuses, 15 to 23 weeks' gestation, were subjected to intrauterine exchange transfusion under direct vision with a fetoscope prior to therapeutic abortion. A maximum of 30 ml of blood was exchanged, so that as much as 95% of the blood in the fetoplacental circulation was of donor origin. The technique clearly has potential value in the management of severe rhesus-hemolytic disease of newborn infants.
D001805:Blood Transfusion, Intrauterine / Q000379:methods*; D004899:Erythroblastosis, Fetal / Q000517:prevention & control / Q000628:therapy; D004906:Erythrocyte Count; D004909:Erythrocyte Indices; D005078:Exchange Transfusion, Whole Blood / Q000379:methods*; D005260:Female; D005312:Fetal Blood / Q000502:physiology; D005332:Fetoscopy; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second