Identification and quantification of alpha-methylfentanyl in post mortem specimens.
Alpha-methylfentanyl, a potent and illicit narcotic, was isolated and identified in post mortem tissues of a drug overdose victim. Quantification was performed with a gas chromatograph equipped with a nitrogen-phosphorous detector (GC/NPD). Alpha-methylfentanyl concentrations of 78 ng/g, 3.1 ng/mL, and 6.4 ng/mL were obtained for liver, blood, and bile, respectively. Conclusive identification of methylfentanyl was accomplished by mass spectrometry. Despropionylmethylfentanyl was also detected in the extracts of the victim's tissues.
D000328:Adult; D001646:Bile / Q000032:analysis; D005283:Fentanyl / Q000031:analogs & derivatives* / Q000097:blood / Q000302:isolation & purification / Q000506:poisoning; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D013287:Illicit Drugs / Q000506:poisoning*; D008099:Liver / Q000032:analysis; D008297:Male; D011041:Poisoning
D013287:Illicit Drugs; C031638:alpha-methylfentanyl; C030592:3-methylfentanyl; D005283:Fentanyl