[Osteomalacia caused by hypovitaminosis with moderate secondary hyperparathyroidism (so-called intestinal osteopathy) on the basis of endemic sprue in a condition of post-celiac disease 1948 and insufficient ultraviolet exposure].
Painful sacro-iliac joints and hips in a 37 year old male patient caused difficulties in differential diagnosis because of scintigraphic positive scans over the sacro-iliac joints: intestinal hypovitaminotic osteomalacia or ankylosing spondylitis? Laboratory findings with low serum calcium, low urine calcium, high alkaline phosphatase and low 25-Hydroxy-vitamin D levels together with high levels of parathormone led to the final diagnosis of osteomalacia. Typical x-ray changes were also present. Prompt relief of clinical symptoms was achieved by high dose vitamin-D therapy.
D000328:Adult; D002446:Celiac Disease / Q000150:complications*; D003937:Diagnosis, Differential; D006615:Hip / Q000000981:diagnostic imaging; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology*; D008297:Male; D010018:Osteomalacia / Q000175:diagnosis / Q000209:etiology*; D013167:Spondylitis, Ankylosing / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014466:Ultraviolet Rays; D014808:Vitamin D Deficiency / Q000150:complications*
Hypovitaminotische Osteomalazie mit mässiggradigem sekundärem Hyperparathyreoidismus (sog. intestinale Osteopathie) auf dem Boden einer endemischen Sprue bei Zustand nach Zöliakie 1948 und insuffizienter UV-Insolation.