Hemoglobin polymorphism in inbred strains of rats (Rattus norvegicus).
Hemoglobin phenotypes A and B were determined by polyacrylamide gel electrophoresis of erythrocyte lysates from 29 inbred strains of rats. Fourteen strains have phenotype A and fifteen have phenotype B, which are characterized by five and six hemoglobin bands, respectively. Breeding studies showed that the phenotypes are codominant and that they segregate in a simple Mendelian fashion in the (A x B) F1 x A backcross. Sex and hemoglobin phenotype assort independently, and the hemoglobin phenotype is not linked to the major histocompatibility complex (RT1) and to two erythrocyte alloantigenic systems (RT2 and RT3).
D000818:Animals; D003433:Crosses, Genetic; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D008040:Genetic Linkage; D006454:Hemoglobins / Q000235:genetics*; D008297:Male; D010641:Phenotype; D011110:Polymorphism, Genetic; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D012727:Sex Characteristics
D006454:Hemoglobins