[Aminoglycoside for the infectious disease associated with acute leukemia. Gentamicin intravenous drip administration (author's transl)].
In 29 patients of infection diseases associated with acute leukemia, 60 to 160 mg/day of gentamicin was injected intravenously drip infusion. The results showed that 69.0% of the cases were clinically effective (excellent+good+fair), and 31% ineffective. Abnormal GOT and GPT level was temporarily noted in 2 cases and audiovestibular dysfunction in 1 case, which improved after the discontinuation of the injection. Safety of the intravenous drip administration of gentamicin was discussed. The patients with acute leukemia might easily have opportunistic infection by Gram negative rods and it is more advantageous to administer intravenously drip infusion than intramuscularly because of hemorrhagic tendency.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D004341:Drug Evaluation; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007263:Infusions, Parenteral; D007938:Leukemia / Q000150:complications*; D008297:Male; D008875:Middle Aged
D005839:Gentamicins