Exocrine protein secretion from human parotid glands during aging: stable release of the acidic proline-rich proteins.
Exocrine protein secretion from stimulated human parotid glands was examined in 220 adults, 20 to 88 years old. A group of parotid proteins, the anionic proline-rich proteins (PRP), was used as a marker for studying protein exocytosis. Data were evaluated as the salivary concentration of PRP (mg%), the percentage of total parotid salivary protein represented by the PRP and as total PRP output (mg/min). No differences were observed in the ability of different-aged males and females to secrete this group of exocrine secretory proteins.
D000328:Adult; D000368:Aged; D000375:Aging; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*; D011392:Proline / Q000378:metabolism*; D055232:Proline-Rich Protein Domains; D012471:Salivary Proteins and Peptides / Q000378:metabolism*
D010455:Peptides; D012471:Salivary Proteins and Peptides; D011392:Proline