Preliminary studies on the carcinogenic effects of Penicillium roqueforti toxin (PR toxin) on rats.
Preliminary results on the carcinogenic activity of a mycotoxin of Penicillium roqueforti (PR toxin) are reported. A squamous epithelioma and a uterine sarcoma were histologically confirmed in 2 of 10 albino rats fed PR toxin in a relatively short time (449 and 551 days respectively). Only an adenocarcinoma was histologically proven within a control group of 10 rats in a significantly longer (931 days) time span.
D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced*; D005260:Female; D006258:Head and Neck Neoplasms / Q000139:chemically induced; D008297:Male; D009183:Mycotoxins / Q000494:pharmacology*; D010407:Penicillium; D051381:Rats; D012509:Sarcoma / Q000139:chemically induced*; D014594:Uterine Neoplasms / Q000139:chemically induced
D009183:Mycotoxins