Mercurial toxicity in the liver of a freshwater teleost Channa punctatus.
Alterations in the activities of alkaline phosphatase, acid phosphatase, glucose-6-phosphatase, succinic dehydrogenase, pyruvic dehydrogenase and lactic dehydrogenase in liver a teleost fish, Channa punctatus were examined after 7, 15 and 30 days treatments with 5 micrograms/l mercuric chloride. Observations have shown specific effects of Hg on these enzymes for a particular period. However, alkaline phosphatase, acid phosphatase, glucose-6-phosphatase were progressively inhibited by this element. Greater accumulation of Hg in liver after a longer treatment and the respective change in enzyme activity clearly showed a dose-response relationship.
D000818:Animals; D005399:Fishes / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008628:Mercury / Q000378:metabolism / Q000633:toxicity*; D013997:Time Factors
D008628:Mercury