Biological properties of Trimeresurus mucrosquamatus venom and its fractions.
Trimeresurus mucrosquamatus venom was separated into two principle fractions by Sephadex G-100 gel filtration. Fraction I (FI) contained the main part of lethal and hemorrhagic activities and minor part of proteolytic activity on casein. The lethal dose of FI determined by the i. v. injection was significantly smaller than that of the i. p. injection, while the result of fraction II (FII) was reversed. The venom was susceptible to heat, pH and cysteine-HCl but not to albumin, sodium glutamate, sorbitol and glycine.
D000818:Animals; D002850:Chromatography, Gel; D003435:Crotalid Venoms / Q000032:analysis / Q000633:toxicity*; D006863:Hydrogen-Ion Concentration; D051379:Mice; D008813:Mice, Inbred ICR; D013696:Temperature
D003435:Crotalid Venoms