Biochemical and biological characteristics of leucocyte proteinase inhibitors.
Pig leucocytes contain inhibitors of neutral and thiol proteinases. These proteins could be isolated from post-granule supernatant fraction as well as from nuclear extract using ion exchange chromatography, gel chromatography and affinity chromatography. Inhibitors differ in molecular weight, isoelectric point, immunologically and their inhibition ability against tested enzymes.
D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007962:Leukocytes / Q000201:enzymology* / Q000648:ultrastructure; D011480:Protease Inhibitors / Q000097:blood* / Q000302:isolation & purification; D013347:Subcellular Fractions / Q000201:enzymology; D013379:Substrate Specificity
D011480:Protease Inhibitors