[Use of liposome-bound x-ray contrast substances for the diagnosis of splenic lesions in generalized lymphoma in SJL/J mice].
An X-ray procedure for diagnosis of splenic lesions in sjl/j mice with generalized lymphoma, using verographin contained in liposomes, is discussed. Intravenous injections of the preparation were followed by changes in X-ray pictures of the spleen in 9 out of 21 mice aged 11-13 weeks which were interpreted as total or local lesions. The X-ray diagnoses were confirmed by histological examination. Due to application of the method lesions with diameters down to 1 mm may be detected.
D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage*; D003974:Diatrizoate Meglumine / Q000008:administration & dosage; D004353:Drug Evaluation, Preclinical; D006689:Hodgkin Disease / Q000000981:diagnostic imaging*; D008081:Liposomes / Q000008:administration & dosage*; D051379:Mice; D008815:Mice, Inbred Strains; D011859:Radiography; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary
D003287:Contrast Media; D008081:Liposomes; D003974:Diatrizoate Meglumine
Primenenie rentgenokontrastnykh veshchestv, sviazannykh s liposomam, dlia diagnostiki porazheniĭ selezenki pri generalizovannoĭ limfome mysheĭ SJL/J.