Hydroa vacciniforme: diagnosis and therapy.
Hydroa vacciniforme is a rare, chronic photodermatosis with onset in childhood. Multiple exposures to UV-A reproduced the symptoms and the vesicular and scarring lesions typical of the sun-induced disease in our patient. Treatment with hydroxychloroquine sulfate, but not indomethacin, reduced the photosensitivity both to sunlight and to artificial UV-A light. Serum complement levels were low while the disease was active and returned to normal after treatment of the patient with hydroxychloroquine.
D000293:Adolescent; D003176:Complement C3 / Q000172:deficiency; D006801:Humans; D006837:Hydroa Vacciniforme / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008297:Male; D012882:Skin Tests; D014466:Ultraviolet Rays / Q000009:adverse effects
D003176:Complement C3; D006886:Hydroxychloroquine