[Content of 17 beta éstradiol, progesterone and glucocorticoid receptors in patients with benign breast diseases].
The levels of estradiol-17 beta, progesterone and glucocorticoids were assayed in tumor tissues from 41 patients with benign breast tumors. Histologically, 21 tumors were identified as fibroadenomas of various types, 14--as fibrous-cystic non-proliferative mastopathy and 6--proliferative mastopathy. Tumor tissue contained estradiol receptors in 51% of cases, all three types of receptors--in 7% and none of the receptors was found in 29% of tumors. The levels of estrogen and glucocorticoids in cases of benign tumors were lower than those in cancer patients. However, in proliferative fibrous-cystic mastopathy group, estrogen receptor level was higher than in the other two groups.
D000232:Adenofibroma / Q000032:analysis*; D000328:Adult; D001940:Breast / Q000032:analysis; D001941:Breast Diseases; D001943:Breast Neoplasms / Q000032:analysis*; D004958:Estradiol / Q000032:analysis*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000032:analysis*; D011965:Receptors, Glucocorticoid / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D011987:Receptors, Steroid / Q000032:analysis*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011965:Receptors, Glucocorticoid; D011980:Receptors, Progesterone; D011987:Receptors, Steroid; D004958:Estradiol
Soderzhanie retseptorov éstradiola-17 beta, progesterona i gliukokortikoidov u bol'nykh dobrokachestvennymi zabolevaniiami molochnoĭ zhelezy.