Structural and functional studies of hemoglobin Barcelona (alpha 2 beta 2 94 Asp (FG1) replaced by His). Consequences of altering an important intrachain salt bridge involved in the alkaline Bohr effect.
D000596:Amino Acids / Q000032:analysis; D004220:Disulfides; D006455:Hemoglobins, Abnormal; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing; D010108:Oxyhemoglobins / Q000378:metabolism; D010446:Peptide Fragments; D010833:Phytic Acid / Q000494:pharmacology; D011086:Polycythemia / Q000097:blood; D011485:Protein Binding; D011725:Pyridines; D013056:Spectrophotometry, Ultraviolet
D000596:Amino Acids; D004220:Disulfides; D006455:Hemoglobins, Abnormal; D010108:Oxyhemoglobins; D010446:Peptide Fragments; D011725:Pyridines; C007542:4,4'-dipyridyl disulfide; D010833:Phytic Acid; C033535:hemoglobin Barcelona