[Experimental retinal detachment on the isolated retina-sclera-preparation and measurement of the subretinal pressure (author's transl)].
It is possible to produce a local retinal detachment on the isolated retina-sclera-preäparation of a rabbit eye by aid of a micropipette, which is placed into the retinal pigment epithelial interface. A Ringer's solution, stained with fluorescein was infused by a micropump with constant infusionsrate. Thereby the retina was separated from the pigment-epithelium in form of a small vesicle. A second micropipette, inserted into the vesicle allowed the measurement of the subretinal pressure. A relationship between pressure level and the time post enucleation could be found. The pressure level during constant infusion seems to be a parameter of the adhesive force between retina and pigmentepithelium.
D000818:Animals; D004195:Disease Models, Animal; D007429:Intraocular Pressure; D011817:Rabbits; D012163:Retinal Detachment / Q000473:pathology*
Artefizielle Ablatio am isolierten Retina-Sklera-Präparat des Kaninchens, mit Druckmessungen im subretinalen Raum.