Malignant angioendotheliomatosis proliferans treated with doxorubicin.
An 84-year-old man was examined for progressive pain, edema, and infiltrating skin lesions on his lower extremities. A skin biopsy specimen confirmed the suspected diagnosis of angioendotheliomatosis proliferans. The clinical course and histologic changes suggested the malignant form of this disease. Treatment with intravenous doxorubicin hydrochloride caused a complete clinical remission.
D000368:Aged; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D006390:Hemangioendothelioma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007263:Infusions, Parenteral; D007866:Leg; D008297:Male; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology
D004317:Doxorubicin