[Determination of the labeling index in stomach tumors (preliminary report)].
The results of measurement of labelling index in tumor tissues and the so-called "normal" gastric mucosa, used as a cell kinetics parameter, were compared in 21 cases of stomach cancer. A procedure of double labeling DNA-synthesizing cells with different concentrations of 3H-thymidine was applied. Tumor tissue samples and specimens of gastric mucosa obtained at a distance of 5-10 cm from the visible boundary of tumor were labeled simultaneously, and a significant difference in labeling index in the tissue samples was observed. Mean labeling index in tumor tissue was 29.66% +/- 1.32, while in normal mucosa - 5.76% +/- 0.76. The procedure may be recommended for early diagnosis of cancer.
D000328:Adult; D000368:Aged; D001345:Autoradiography; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013936:Thymidine; D014316:Tritium
D014316:Tritium; D013936:Thymidine
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