[Effect of proteolysis inhibitors on the phagocytic activity and leukocyte cytoplasmic enzyme activity of white mice with streptococcal peritonitis].
The functional and metabolic properties of neutrophils in white mice were studied in the course of streptococcal peritonitis and after treatment by the intraperitoneal injection of normal rabbit serum, antitryptic and antikallikrein immune sera and inhitryl. Protease inhibitors were shown to activate the bactericidal and phagocytic activity of neutrophils, to normalize oxidation processes and to enhance the metabolism of glycogen.
D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D004353:Drug Evaluation, Preclinical; D006003:Glycogen / Q000097:blood; D007962:Leukocytes / Q000201:enzymology*; D051379:Mice; D009504:Neutrophils / Q000201:enzymology; D010088:Oxidoreductases / Q000097:blood; D010538:Peritonitis / Q000188:drug therapy* / Q000201:enzymology; D010587:Phagocytosis / Q000187:drug effects*; D011480:Protease Inhibitors / Q000627:therapeutic use*; D013290:Streptococcal Infections / Q000188:drug therapy* / Q000201:enzymology
D011480:Protease Inhibitors; D006003:Glycogen; D010088:Oxidoreductases
Vliianie ingibitorov proteoliza na fagotsitarnuiu aktivnost' i aktivnost' tsitoplazmaticheskikh fermentov leĭkotsitov belykh mysheĭ pri streptokokkovom peritonite.