The effects of radiotherapy on the integrity of the ureteroileal segment following cystectomy.
Thirty-nine patients treated by cystectomy and ileal loop diversion for carcinoma of bladder were divided into 3 groups: A. cystectomy alone, B. cystectomy combined with pre-operative irradiation, C. Salvage cystectomy following radical radiotherapy. The post-operative complications and subsequent function of the ureteroileal segment of the urinary diversion were compared in the 3 groups. Those having primary cystectomy had the fewest complications and best long-term function, whilst those having surgery within 12 months of radical radiotherapy had the highest incidence of ureteroileal obstruction. The possible aetiology is discussed.
D005260:Female; D006801:Humans; D007082:Ileum / Q000528:radiation effects; D008297:Male; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*; D014513:Ureter / Q000528:radiation effects; D001743:Urinary Bladder / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014547:Urinary Diversion