Surface membrane proteins and glycoproteins of red blood cells from normal and anaemic mice.
1. The surface membrane proteins of red blood cells from normal, hyperbled or acetylphenylhydrazine-treated BALB/c mice and NZB mice of different ages were labelled by lactoperoxidase-catalyzed radioiodination. Sialoglyoproteins were labelled by periodate/NaB3H4 or galactose oxidase +/- neuraminidase/Na3H4 treatments. 2. Anaemia produced several changes in radioiodinated proteins. 3. Sialoglycoprotein radiolabelling was unchanged, even with over 90% reticulocytosis. 4. Decreased periodate/NaB3H4-dependent labelling of red blood cells from Plasmodium berghei-infected BALB/c mice (Howard et al., 1980; Howard & Day, 1981) cannot therefore be due to anaemia per se, but must be related more specifically with infection.
D000375:Aging; D000740:Anemia / Q000097:blood*; D000818:Animals; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D006023:Glycoproteins / Q000097:blood*; D008565:Membrane Proteins / Q000097:blood*; D051379:Mice; D008807:Mice, Inbred BALB C; D010659:Phenylhydrazines; D012016:Reference Values; D012795:Sialoglycoproteins / Q000097:blood
D006023:Glycoproteins; D008565:Membrane Proteins; D010659:Phenylhydrazines; D012795:Sialoglycoproteins; C006384:N(1)-acetylphenylhydrazine