Analysis of hepatitis virus DNA in the liver and serum of HBe antigen positive chimpanzee carriers.
Hepatitis B viral DNA present in the liver of HBe antigen positive chimpanzee carriers is in the form of viral molecules (3.2 Kb) and no integration into host DNA was observed. The 3.2 Kb form was not detected in the serum. Other discrete HBV DNA species with faster mobilities than the major 3.2 Kb were consistently detected both in the liver and in the serum and their possible significance is discussed.
D000818:Animals; D002353:Carrier State / Q000382:microbiology*; D004279:DNA, Viral / Q000032:analysis* / Q000097:blood; D006509:Hepatitis B / Q000382:microbiology*; D006513:Hepatitis B e Antigens / Q000276:immunology; D006515:Hepatitis B virus / Q000235:genetics*; D008099:Liver / Q000032:analysis*; D009693:Nucleic Acid Hybridization; D011995:Recombination, Genetic
D004279:DNA, Viral; D006513:Hepatitis B e Antigens