Ultrastructure of the regenerating growth cones of catecholamine nerve terminals in rat hypothalamic nuclei after 5,7-dihydroxytryptamine administration.
Ultrastructure of the regenerating growth cones of catecholamine axons is examined in the paraventricular nucleus and median eminence of the rat. Growth cones are observed during 1 to 4 months, and most frequently at 2 months, after the administration of 300 microgram of 5,7-DHT in the lateral ventricle. The growth cones of catecholamine axons are characterized by an accumulation of branching smooth endoplasmic reticula which contain dense material.
D015116:5,7-Dihydroxytryptamine / Q000494:pharmacology*; D000818:Animals; D001369:Axons / Q000187:drug effects; D002799:Cholinergic Fibers / Q000187:drug effects*; D004102:Dihydroxytryptamines / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism; D007031:Hypothalamus / Q000187:drug effects*; D008297:Male; D008473:Median Eminence / Q000187:drug effects; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D009416:Nerve Regeneration / Q000187:drug effects*; D009638:Norepinephrine / Q000378:metabolism; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000187:drug effects
D004102:Dihydroxytryptamines; D015116:5,7-Dihydroxytryptamine; D004298:Dopamine; D009638:Norepinephrine