Improved characterization of healthy and malignant tissue by NMR line-shape relaxation correlations.
We performed a relaxation-line-shape correlation NMR experiment on muscle, liver, kidney, and spleen tissues of healthy mice and of mouse tumor tissue. In each tissue studied, five spin groups were resolved and characterized by their relaxation parameters. We report a previously uncharacterized semi-solid spin group and discuss briefly the value of this method for the identification of malignant tissues.
D000818:Animals; D005354:Fibrosarcoma / Q000473:pathology*; D007668:Kidney / Q000033:anatomy & histology; D008099:Liver / Q000033:anatomy & histology; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D051379:Mice; D008807:Mice, Inbred BALB C; D009132:Muscles / Q000033:anatomy & histology; D013154:Spleen / Q000033:anatomy & histology