Human chromosomes control growth of human-Chinese hamster somatic cell hybrids.
Several independent human-Chinese hamster hybrid cell lines have been monitored for growth rate and chromosome composition. The rate of growth, as indicated by doubling time during log phase, was positively correlated with the number of human chromosomes, and human chromosomes 3 and 21 were present in stable hybrid cell lines more frequently than expected.
D000818:Animals; D002455:Cell Division; D002877:Chromosomes, Human; D006224:Cricetinae; D003412:Cricetulus; D006801:Humans; D006822:Hybrid Cells / Q000502:physiology*; D007621:Karyotyping; D013997:Time Factors