Open heart surgery in a patient with homozygous sickle cell disease.
A child in heart failure with homozygous sickle cell disease underwent corrective surgery on cardiopulmonary bypass. The use of early intra-operative exchange transfusion produced a rapid fall in the level of HbS. Postoperatively she developed falciparum malaria which responded to treatment. She was eventually discharged home to Nigeria 8 weeks after her operation.
D000755:Anemia, Sickle Cell; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D002675:Child, Preschool; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans
D006451:Hemoglobin, Sickle