Glucose utilization increases in choroid plexus during slow wave sleep. A [14C] deoxyglucose study in the cat.
Glucose utilization (GU) was measured during spontaneous waking and slow-wave sleep (SWS) by adaptation of the [14C]deoxyglucose method to the unrestrained cat. In sleeping animals a greater autoradiographic signal between choroid plexus (CP) and the rest of brain was noticed. Quantification provided an index of the metabolic rate of CP and confirmed that mean values for GU were significantly higher in "sleeping' than in "awake' cats.
D000818:Animals; D001345:Autoradiography; D002250:Carbon Radioisotopes; D002415:Cats; D002831:Choroid Plexus / Q000378:metabolism*; D003837:Deoxy Sugars / Q000378:metabolism*; D003847:Deoxyglucose / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D012894:Sleep Stages / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology
D002250:Carbon Radioisotopes; D003837:Deoxy Sugars; D003847:Deoxyglucose; D005947:Glucose