Inhibition of hepatic gluconeogenesis and lipogenesis by benzoic acid, p-tert.-butylbenzoic acid, and a structurally related hypolipidemic agent SC-33459.
D000818:Animals; D001565:Benzoates / Q000494:pharmacology*; D019817:Benzoic Acid; D005215:Fasting; D005227:Fatty Acids / Q000096:biosynthesis; D005260:Female; D005502:Food; D005943:Gluconeogenesis / Q000187:drug effects*; D005947:Glucose / Q000096:biosynthesis; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism*; D011714:Pyrans / Q000494:pharmacology*; D011753:Pyrones / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D001565:Benzoates; D005227:Fatty Acids; D000960:Hypolipidemic Agents; D008055:Lipids; D011714:Pyrans; D011753:Pyrones; C034290:4-tert-butylbenzoic acid; C034291:SC 33459; D019817:Benzoic Acid; D005947:Glucose