Enhancing effect of saccharated ferric oxide on human lymphocyte transformation in serum-free medium.
The effect of saccharated ferric oxide on the response of human peripheral lymphocytes to stimulation by phytohemagglutinin in serum-free medium was studied by measuring the incorporation of [3H]thymidine into DNA. The addition of saccharated ferric oxide resulted in a significant increase in [3H]thymidine uptake not only with mitogen added, but also without mitogen, suggesting that this compound itself was mitogenic.
D002478:Cells, Cultured; D004261:DNA Replication / Q000187:drug effects; D005290:Ferric Compounds / Q000494:pharmacology*; D000077605:Ferric Oxide, Saccharated; D005937:Glucaric Acid; D006801:Humans; D007501:Iron / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects*
D005290:Ferric Compounds; D007501:Iron; D000077605:Ferric Oxide, Saccharated; D005937:Glucaric Acid