Changes in acid phosphatase activity in the substantia gelatinosa in response to pain.
Two-day and 15-day-old offspring of capsaicin-pretreated Wistar rats were given subcutaneous injections of a 5% formalin solution to the dorsal aspect of the right forepaw. One hour after injection, acid phosphatase activity of the substantia gelatinosa of formalin/capsaicin cervical sections was significantly greater bilaterally than in saline/capsaicin 15-day-old animals. In 2-day-old animals the formalin/control right cervical sections had significantly higher acid phosphatase activity than saline/control. These results are further support for a direct functional relation between activity in the substantia gelatinosa and chemogenic pain stimulus.
D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn; D002211:Capsaicin / Q000633:toxicity; D005260:Female; D005552:Forelimb / Q000294:innervation; D005557:Formaldehyde / Q000633:toxicity; D009619:Nociceptors / Q000187:drug effects / Q000201:enzymology*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000201:enzymology*; D013376:Substantia Gelatinosa / Q000187:drug effects / Q000201:enzymology*
D005557:Formaldehyde; D000135:Acid Phosphatase; D002211:Capsaicin