Occlusion of the digital arteries -- A model for pathogenesis of navicular disease.
The digital arteries of 10 horses suffering from navicular disease, and 7 horses from a control group, were examined angiographically. The horses from the disease group showed complete or partial occlusion of the digital arteries in all cases. In the control group of 7 healthy horses, isolated vessel obstructions were also found but these were limited to narrowing of part of an artery only. Histological investigations showed that total occlusion of a vessel involved an organised thrombus but that partial occlusion generally involved changes to the vascular wall, similar to those caused by endarteritis obliterans. The vessel changes are discussed, with particular reference to their possible significance as a cause of navicular disease.
D000818:Animals; D001847:Bone Diseases / Q000209:etiology / Q000662:veterinary*; D004692:Endarteritis / Q000150:complications / Q000662:veterinary; D005534:Foot Diseases / Q000209:etiology; D005552:Forelimb; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D013927:Thrombosis / Q000150:complications / Q000662:veterinary; D014034:Toes / Q000098:blood supply*; D014652:Vascular Diseases / Q000662:veterinary*