Synthesis and evaluation of substituted 4(3H)-quinazolone derivatives for antimicrobial and antiacetylcholinesterase activities. Part 3.
The synthesis of some new 6,8-dibromo-2-N-(N-arylcarbamoyl) carbamoylmethylthio-3-aryl-4(3H)-quinazolone derivatives is described. The synthesized derivatives were screened for their antibacterial, antifungal and antiacetylcholinesterase activities in vitro. Most of the compounds exhibited interesting antimicrobial activities. The relation between this and their chemical structure has been studied.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002800:Cholinesterase Inhibitors; D005658:Fungi / Q000187:drug effects; D011799:Quinazolines / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002800:Cholinesterase Inhibitors; D011799:Quinazolines