Value of the minimum bactericidal concentration of antibiotics in the management of a case of recurrent Streptococcus bovis septicaemia.
After prostatectomy a 60-year-old man developed Streptococcus bovis septicaemia. The patient did not respond to treatment with a combination of ampicillin and erythromycin and in vitro antagonism between these antibiotics was demonstrated by minimum bactericidal concentration (MBC). The value of determining the MBC of antibiotics used in the treatment of septicaemia is emphasised.
D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004917:Erythromycin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012008:Recurrence; D018805:Sepsis / Q000188:drug therapy*; D013290:Streptococcal Infections / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D004917:Erythromycin; D000667:Ampicillin