[Bronchodilation in childhood asthma bronchiale (author's transl)].
The bronchodilation in childhood asthma bronchiale was studied by means of the suitable form of administration for that age, the paediatric syrup. We have chosen as active substance the hexoprenaline which has a long standing as a modern beta-2-selective bronchodilator. 2 different doses confirm a good effect and provide some margin, which is highly welcome, especially so in paediatry. The paper corroborates the importance of the measurement of the obstruction even in this age to confirm the diagnosis and the proposed therapy, we have used the optimal body plethysmography for that purpose. The plotting of the obstruction-pressure curve, which is a prerequisite for the calculation of the resistance, however, presents some methodical difficulties in infantile patients. The former statement of a possible sole information on the obstruction via the beta-flow curve was confirmed in a regression equation, it allows an about 80% significant determination of the resistance even without the alpha-curve.
D000284:Administration, Oral; D000403:Airway Resistance; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy*; D002648:Child; D005260:Female; D006594:Hexoprenaline / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010627:Phenethylamines / Q000627:therapeutic use*; D010993:Plethysmography, Whole Body; D012996:Solutions
D010627:Phenethylamines; D012996:Solutions; D006594:Hexoprenaline
Broncholyse beim kindlichen Asthma.