In vitro study of lysosomal particles in corneal epithelium cultures after type I herpes virus infection.
The lysosomal cycle has been studied in the primary cultures of corneal epithelium infected with type I herpes virus. Immediately after the infection, the lysosomal system develops. There is a great dispersion in the morphometric analysis of the lysosomal particles. They represent a heterogeneous population with regard to their size. The number of lysosomal particles increases very rapidly during the first hours after the herpetic infection. Finally, many cells become round and die.
D000818:Animals; D002478:Cells, Cultured; D003315:Cornea / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D007635:Keratitis, Dendritic / Q000473:pathology*; D008247:Lysosomes / Q000473:pathology*; D011817:Rabbits