Cross-reactivity between Acacia (wattle) and rye grass pollen allergens. Detection of allergens in Acacia (wattle) pollen.
Immunoglobulin E (IgE), directed against components of Acacia (wattle) pollen, has been detected by radioallergosorbent tests (RAST) in the sera of some children and adults who develop allergic symptoms in the presence of flowering Acacia trees in Australia. All these subjects also had high levels of IgE directed against Lolium perenne (rye grass) pollen. Inhibition by RAST showed that most of the IgE molecules which bound to Acacia pollen components also bound to L. perenne pollen extracts, and to Glycoprotein 1, the major allergen of L. perenne pollen. In these assays, the allergens have been immobilized on polyvinyl chloride microtitre trays: the sensitivity of this approach is compared to that of commercial RAST kits.
D000045:Acacia / Q000276:immunology*; D000328:Adult; D001666:Binding Sites, Antibody; D001667:Binding, Competitive; D002648:Child; D003231:Conjunctivitis / Q000175:diagnosis / Q000276:immunology; D003429:Cross Reactions; D002523:Edible Grain / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000032:analysis / Q000096:biosynthesis; D010936:Plant Extracts / Q000276:immunology; D011058:Pollen / Q000032:analysis / Q000276:immunology*; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000276:immunology; D012434:Secale / Q000276:immunology*; D012882:Skin Tests
D007074:Immunoglobulin G; D010936:Plant Extracts; D007073:Immunoglobulin E