Peripheral factors as limitations to exercise capacity.
The paper focuses on two aspects of the peripheral limitations to exercise: (a) intracellular and extracellular substrates used for energy transduction and (b) the metabolic potential of muscle. The major substrates used to support contractile activity have been discussed in reference to high-intensity, short-term exercise and moderately-intense, long-term exercise. It has been suggested that substrate availability is a prime candidate as a limiting factor to prolonged exercise, whereas, it is clearly not a limiting factor in short-term maximal efforts. Consideration of the metabolic potential of muscle as a possible limiting factor to exercise has been divided into anaerobic metabolism, aerobic metabolism and regulatory factors. It appears that the enzymatic capacity of the energy transducing pathways is not a limiting factor to any type of exercise.
D000693:Anaerobiosis; D050260:Carbohydrate Metabolism; D004734:Energy Metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D010710:Phosphates / Q000378:metabolism; D005082:Physical Exertion; D013178:Sports Medicine
D008055:Lipids; D010710:Phosphates; D005947:Glucose