Difference in thermal stability of type-I and type-II collagen from rat skin.
Type-I and type-III collagens were obtained by differential salt fractionation of neutral-salt-soluble collagen from rat skin. Their thermal stabilities were determined by u.v. difference spectroscopy. The ;melting' temperature (T(m)) in 5mm-acetic acid of type-III collagen was almost 2 degrees C above that of type-I collagen. Intramolecular covalent cross-linking had no effect on the thermal stability.
D000818:Animals; D003094:Collagen / Q000378:metabolism; D006358:Hot Temperature; D007842:Lathyrism / Q000378:metabolism; D008297:Male; D011489:Protein Denaturation; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D003094:Collagen