[Experimental test of two tissue adhesives (GRF and IBC 2) in vascular microsurgery in the rat (author's transl)].
Tissues adhesives have been evaluated on rats, during microvascular surgery: the IBC 2 and the GRF glues. The short and long term evolution is studied. The patency rate of the anastomosis is analyzed and the histological aspect is studied. The GRF glue exhibits a rapid resorption rate, but the long term results show a high toxicity against the muscular layers of the artery. The IBC 2 glue has a slower resorption rate and its long term effect are restricted to a foreign body reaction.
D000818:Animals; D001012:Aorta, Abdominal / Q000473:pathology / Q000601:surgery; D002015:Bucrylate / Q000633:toxicity; D003487:Cyanoacrylates / Q000633:toxicity; D004338:Drug Combinations / Q000633:toxicity; D005557:Formaldehyde / Q000633:toxicity; D005780:Gelatin / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D012118:Resorcinols / Q000633:toxicity; D014014:Tissue Adhesives / Q000633:toxicity; D014656:Vascular Surgical Procedures / Q000379:methods*
D003487:Cyanoacrylates; D004338:Drug Combinations; D012118:Resorcinols; D014014:Tissue Adhesives; C027813:gelatin-resorcinol-formaldehyde tissue adhesive; D005557:Formaldehyde; D002015:Bucrylate; D005780:Gelatin
Utilisation expérimentale des colles biologiques gélatine résorcine formol (GRF) et isobutyl 2 cyanoacrylate (IBC 2) en microchirurgie vasculaire chez le rat.