Analysis of a follow-up study: an example from asbestos-exposed insulation workers.
An 11-a follow-up study was carried out on a working population of asbestos insulation workers to investigate the possible progression of symptoms and signs. A total of 166 men had repeat radiology, and the 43 men who had progressed in radiography category of profusion of small irregular opacities (as determined by the ILO U/C International Classification of Radiographs of Pneumoconioses, 1980) comprised 37 (32%) of the 117 smokers, 3 (17%) of the 18 exsmokers, and 3 (10%) of the 31 nonsmokers. For 148 men over 20 a of age at the time of original study, and with lung function measured in both surveys, smoking was associated with a significantly reduced transfer factor (TLCO). For smokers in category 0 at first survey, a low TLCO was associated with subsequent progression to higher radiographic categories.
D000328:Adult; D000704:Analysis of Variance; D001194:Asbestos / Q000009:adverse effects; D004812:Epidemiologic Methods; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009660:Northern Ireland; D009784:Occupational Diseases / Q000503:physiopathology; D012907:Smoking
D001194:Asbestos