The effect of squalane on the absorption of dietary cholesterol by the rat.
Replacement of dietary triglyceride by a saturated hydrocarbon, squalane, resulted in a significant reduction (up to 50%) of cholesterol absorption of control values. Squalane may be useful in the treatment of dietary hypercholesterolemia.
D000818:Animals; D002791:Cholesterol, Dietary / Q000378:metabolism*; D007408:Intestinal Absorption / Q000187:drug effects*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013185:Squalene / Q000494:pharmacology*
D002791:Cholesterol, Dietary; D013185:Squalene