Characteristic features of the smooth muscle cell migration in vascular wall injury.
Characteristic features of the smooth muscles cell migration and ghost body formation observed in vascular lesions induced by intravenous administration of Lipofundin-S (Braun, Melsungen) were studied and compared to lesions seen in other models. Phenomena revealed can be explained by alterations of the cell environment. The cell, producing ghost body looses a part of the cytoplasm and complies with the new environment. Thus ghost bodies play an active part in maintaining the equilibrium between the cell and its environment.
D000818:Animals; D001011:Aorta / Q000473:pathology* / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000139:chemically induced / Q000473:pathology*; D002465:Cell Movement; D004195:Disease Models, Animal; D004338:Drug Combinations / Q000009:adverse effects; D004655:Emulsions / Q000009:adverse effects; D008854:Microscopy, Electron; D009131:Muscle, Smooth, Vascular / Q000473:pathology* / Q000648:ultrastructure; D010743:Phospholipids / Q000009:adverse effects; D011817:Rabbits; D051381:Rats; D013012:Sorbitol / Q000009:adverse effects
D004338:Drug Combinations; D004655:Emulsions; D010743:Phospholipids; C008288:Lipofundin; D013012:Sorbitol