Chemiluminescence assay for detection of anti-platelet antibodies.
A chemiluminescence (CL) assay for detection of antiplatelet antibodies was developed. Platelets sensitized with a xenogeneic antiplatelet serum or a potent anti-Pla1 serum stimulated granulocytes to produce CL. Other antibodies detectable by 51chromium release and immunofluorescent assays were not discerned by the CL assays.
D000906:Antibodies / Q000032:analysis*; D001792:Blood Platelets / Q000276:immunology*; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D008165:Luminol; D009895:Opsonin Proteins; D010587:Phagocytosis
D000906:Antibodies; D009895:Opsonin Proteins; D008165:Luminol