Homologous controlled-viscosity fibrin for endovascular embolization. Part I. Experimental development of the medium.
The author used a two-component adhesive (homologous fibrinogen and thrombin) to develop a medium with controllable rate and extent of setting and coagulation. After mixing with the radiopaque substance metrizamide, the material meets the criteria postulated for an endoarterial embolization medium: variable and controllable viscosity, elasticity after setting, absence of toxicity, radio-opacity, and adequate sterilizability. After setting, the fibrin medium is a clear, solid, but soft elastic substance clearly visible on the X-ray film even in fine structures.
D001164:Arteriovenous Fistula / Q000628:therapy; D002340:Carotid Artery Diseases / Q000628:therapy*; D002426:Cavernous Sinus; D004621:Embolization, Therapeutic / Q000379:methods*; D005337:Fibrin / Q000627:therapeutic use*; D006801:Humans; D014783:Viscosity
D005337:Fibrin