[Changes in the rhythm of cardiac activity in hyperactivation of the anterior amygdaloid nucleus].
It was shown in experiments on random-bred rats that the creation of the generator of pathologically enhanced excitation (GPEE) in the anterior amygdaline nucleus causes abnormalities of cardiac rhythm (bradysystole). These effects are realized via the vagus nerves. Discharges of the epileptic activity in the GPEE correlate with breaks of electric activity in the vagus (the central terminal) and cardiac complex loss. Coagulation of the GPEE area in the amygdala and brain cooling which entails the disappearance of GPEE activity lead to the recovery of normal cardiac rhythm. The data obtained are discussed from the standpoint of the general concepts of the role of the central hyperactive determinant structures in the pathology of visceral function regulation.
D000679:Amygdala / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D004558:Electric Stimulation; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D010406:Penicillins / Q000494:pharmacology; D051381:Rats; D014630:Vagus Nerve / Q000502:physiology
D010406:Penicillins
Izmenenie ritma serdechnoĭ deiatel'nosti pri giperaktivatsii perednego amigdaliarnogo iadra.