[The treatment of Schistosomiasis mansoni with RP 35972 (Oltipraz). Preliminary results (author's transl)].
First in Madagascar, a new drug the RP 35972 (Oltipraz) was used for the treatment of Schistosomiasis mansoni. clinical investigations confirm that any toxic action by this drug was observed. Oltipraz in doses of 25-35 mg/kg body weight was tried in 123 bilharzial patients. The authors obtained a percentage of cure of 90% in the 109 controlled cases and concluded Oltipraz to have been the most satisfactory treatment.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D008875:Middle Aged; D011719:Pyrazines / Q000008:administration & dosage / Q000627:therapeutic use*; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000188:drug therapy*; D012556:Schistosomicides / Q000627:therapeutic use*; D013871:Thiones; D013876:Thiophenes
D011719:Pyrazines; D012556:Schistosomicides; D013871:Thiones; D013876:Thiophenes; C026209:oltipraz
Traitement de la bilharziose à Schistosoma mansoni par le RP 35972 (Oltipraz). Résultats préliminaires des premiers traitements à Madagascar.