The behaviour of immunoglobulins in children and adolescents hyposensitized for pollinosis and pollen asthma.
The levels of immunoglobulins E, G, A and M in pre- and post-hyposensitized sera were determined in 28 children and adolescents (aged from 5 to 19 years) with pollinosis and pollen asthma. "Pollinex" was used for hyposensitization. The treatment was begun before the pollen season, successively over 1 to 3 years. The following results were obtained IgE increased in 46.7% of the patients, IgG and IgA were normal in 75% and 85.7% respectively. IgG increased after hyposensitization, but the values remained within normal limits. IgM exceeded normal values in 53.6% of the patients before treatment. Following successive hyposensitization, a statistically significant increase in IgE and a statistically insignificant increase in IgG were observed. IgA values increased only slightly.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003888:Desensitization, Immunologic; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000628:therapy*; D007136:Immunoglobulins / Q000032:analysis*; D011058:Pollen / Q000276:immunology*
D007136:Immunoglobulins