Unusual bone marrow visualization with 99mTc-damaged erythrocytes.
A visualization of the bone marrow beside that of the spleen was obtained with 99mTc-labeled N-ethylmaleimide (NEM) damaged erythrocytes in a patient with systemic lupus erythematosus. This phenomenon could be produced both with autologous and homologous red cells. The patient's NEM-damaged erythrocytes given to a healthy patient did not produce a visualization of the marrow. Such an observation was not present in a series of healthy persons and patients with different disorders to whom labeled and damaged erythrocytes were administered, and has not been reported in the literature so far.
D001853:Bone Marrow / Q000000981:diagnostic imaging*; D002648:Child; D004912:Erythrocytes / Q000187:drug effects; D005033:Ethylmaleimide; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging; D013667:Technetium
D013667:Technetium; D005033:Ethylmaleimide