[Prognosis of cerebral ischemia. Significance of the cerebrospinal fluid lactate level and computer tomographic findings].
In patients (n = 120) with supratentorial ischemic cerebral infarction CSF lactate was determined and a CT was carried out on the 1st, 3rd and 7th day after the stroke. On the 3rd and 7th day the comparative investigation revealed a close correlation between the measure of the ischemic edema and the level of CSF-lactate. Thus the lactate-concentration can be regarded as a measure for the spread of the edema after cerebral infarction. Already on the 3rd day CT- and CSF-lactate results allow a relatively reliable prediction for the course of the stroke. An edema grade III in CT and a CSF-lactate concentration more than 4 mmol/l were prognostically critical. On the other hand good chances of survival were indicated by a CSF lactate level under 2,5 mmol/l and an edema grade I.
D001921:Brain / Q000000981:diagnostic imaging; D001929:Brain Edema / Q000209:etiology; D002545:Brain Ischemia / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D006801:Humans; D007427:Intracranial Pressure; D007773:Lactates / Q000134:cerebrospinal fluid*; D011379:Prognosis; D014057:Tomography, X-Ray Computed
D007773:Lactates
Zur Prognose des ischämischen Hirninfarkts. Bedeutung der Liquor-Laktat-Konzentration und des Befundes im Computer-Tomogramm.