[Study of the associative activity of schizophrenic patients by the technic of remote synchronization of cortical biopotentials].
To reveal physiological correlates of the schizophrenic thinking peculiarities associated with impaired mechanisms of information selection, spatial synchronization of the cortical biopotentials was studied in 10 healthy probands and 9 patients with continuously progressing schizophrenia. Both the healthy probands and the patients were asked to solve problems of comparing notions in situations where standard or non-standard criteria for the solution could be chosen. The bioelectrical activity was recorded at 48 cortical sites with subsequent estimation of the cross-correlation interconnections between the EEGs. It was found that in the solution of problems with the use of standard criteria the spatial-temporary organization of the biopotentials differed but little in the healthy probands and the patients, whereas in the solution of problems for which secondary, latent features of the subjects were required, these differences were rather marked in a number of characteristics, such as the general level of the synchronism, the character of interhemispheral asymmetries, the topographic distribution of the biopotential synchronization. The data obtained are discussed in the light of the present-day concepts on the functional specialization of the hemispheres.
D000293:Adolescent; D001244:Association; D002540:Cerebral Cortex / Q000502:physiology*; D003344:Cortical Synchronization; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography; D006801:Humans; D012565:Schizophrenic Psychology; D014936:Word Association Tests
Issledovanie assotsiativnoĭ deiatel'nosti bol'nykh shizofrenieĭ metodom distantnoĭ sinkhronizatsii biopotentsialov kory golovnogo mozga.