[Viral sequences in the genomes of rat and hamster cells transformed by simian adenovirus SA7(C8) and its DNA].
Four cell lines transformed by simian adenovirus SA7 and its DNA were analysed by means of molecular hybridization. Content of viral DNA sequences in different lines varied from 10% (the left end) of the molecule to the entire genomes. Transcription of the D BglII fragment (coordinates 1.8--10) was observed in all examined lines. The integration type of highly oncogenic simian adenovirus SA7 DNA differed from the pattern of integration of the highly oncogenic human adenovirus type 12 and was similar to that of the non-oncogenic adenoviruses in adenovirus-transformed cells.
D000256:Adenoviridae / Q000235:genetics*; D000260:Adenoviruses, Human / Q000235:genetics; D000261:Adenoviruses, Simian / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002472:Cell Transformation, Viral; D006224:Cricetinae; D004279:DNA, Viral / Q000235:genetics*; D006367:HeLa Cells / Q000502:physiology; D006801:Humans; D007700:Kinetics; D051381:Rats; D013045:Species Specificity; D014158:Transcription, Genetic
D004279:DNA, Viral
Virusnye posledovatel'nosti v genome kletok krys i khomiakov, transformirovannykh adenovirusom obez'ian SA7(C8) i ego DNK.