[Evaluation of pituitary functional periodicity by harmonic analysis. II) Circadian prolactin secretion in acromegaly].
PRL levels over 24 hours have been studied in 9 acromegalic patients (4 men and 4 women). Hormone levels were found significantly higher than age and sex matched normal subjects in 4 cases (2 males and 2 females). PRL and STH levels were significantly correlated in men, but not in women. A 24-hour periodicity of PRL secretion was found in 4 cases, however in 2 of them the phase was anticipated in respect to the control group. In 4 of the remaining subjects the hormone secretion is made up by a succession of episodes with higher frequency than in the control group. Only in one case no significant periodicity of secretion was observed.
D000172:Acromegaly / Q000097:blood*; D000328:Adult; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D011388:Prolactin / Q000097:blood / Q000378:metabolism*
D011388:Prolactin
Valutazione della periodicitià' funzionale dell'ipofisi mediante analisi armonica. - II) La secrezione circadiana di prolattina nell'acromegalia.