Helium ion therapy for choroidal melanoma.
Forty patients with choroidal melanomas received radiation therapy with helium ion-charged particles. Thirty-six of 30 patients either remained stable or demonstrated tumor shrinkage. Seventeen of 18 patients followed up for at least one year after therapy demonstrated tumor regression, with a mean tumor shrinkage of approximately 40%. The most effective method of choroidal melanoma management is unclear. Charged-particle external-beam irradiation may be more applicable and have less ocular morbidity than either radioactive plaques or photocoagulation.
D000328:Adult; D000368:Aged; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D005260:Female; D006371:Helium / Q000627:therapeutic use*; D006801:Humans; D007477:Ions; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000532:radiotherapy*; D008875:Middle Aged; D011879:Radiotherapy Dosage; D014463:Ultrasonography
D007477:Ions; D006371:Helium