Effect of neuroactive material on neurosecretion in adult cockroach. Periplaneta americana (L).
The neurosecretory material is found depleted in the medial neurosecretory cells in adult cockroaches poisoned with insecticide. It is, however, scanty in the neurosecretory pathway but abundant in the corpora cardiaca of these insects. The administration of toxicated haemolymph in the normal cockroach results in scanty material in medial neurosecretory cells, but the accumulation of the neurosecretory material in corpora cardiaca. The toxicated tissue extracts have also caused depletion of neurosecretory material from the medial neurosecretory cells as well as from the axonal tract and its accumulation in the corpora cardiaca. Thus effect is comparatively more pronounced by the extract from the Malpighian tubules and nerve cord than than of brain extract. Thus the effect produced by insecticide on the stimulation--secretion coupling mechanism of neurosecretion is comparable to the produced by the toxicated haemolymph and tissue extract. The possibility of involvement of the adrenergic system in regulating the action of neuroactive material on neurosecretory cells is suggested in the insects.
D000818:Animals; D003058:Cockroaches / Q000502:physiology*; D005278:Fenitrothion / Q000494:pharmacology; D006458:Hemolymph / Q000502:physiology; D009489:Neurosecretion; D009490:Neurosecretory Systems / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D010243:Paralysis / Q000503:physiopathology
D005278:Fenitrothion