The type of current frequency used in transurethral resection of prostate (TURP) affects the androgen receptor.
Blended Bovie current No. 2 destroys androgen receptor in both cytosol and nuclear extracts of prostate tissue. No significant difference was noted in either nuclear or cytosol receptor concentrations between openly resected and electroresected specimens when Bovie current No. 1 was used with cutting loops No. 26 or larger, although total androgen receptor (cytosol plus nuclear) was significantly reduced in the electroresected specimens. The androgen receptor method used is highly reliable for prostate obtained by either open resection or electroresection using pure cutting currents, although receptor concentrations in samples obtained by the two methods probably should not be combined or compared.
D001424:Bacterial Infections; D002467:Cell Nucleus / Q000032:analysis; D003600:Cytosol / Q000032:analysis; D004598:Electrosurgery; D006801:Humans; D008297:Male; D011467:Prostate / Q000032:analysis / Q000601:surgery*; D011472:Prostatitis / Q000601:surgery*; D011944:Receptors, Androgen / Q000032:analysis*; D011987:Receptors, Steroid / Q000032:analysis*; D014521:Urethra / Q000601:surgery*
D011944:Receptors, Androgen; D011987:Receptors, Steroid