Autoanti-K antibody mimicking an alloantibody.
A patient with pancytopenia and hypercellular bone marrow but without evidence of hemolysis had a positive direct antiglobulin test due to a red blood cell autoantibody. Although the patient was K-negative, eluates made from his erythrocytes contained what seemed to be anti-K antibody. The latter could be adsorbed onto and eluted from both K-positive and K-negative cells. We concluded that this patient is another example of autoanti-K antibody mimicking an alloanti-K antibody.
D000368:Aged; D000918:Antibody Specificity; D001323:Autoantibodies / Q000032:analysis* / Q000276:immunology; D001789:Blood Group Antigens / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D001803:Blood Transfusion; D003298:Coombs Test; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D007518:Isoantibodies / Q000032:analysis* / Q000276:immunology; D007626:Kell Blood-Group System / Q000276:immunology*; D008297:Male; D010198:Pancytopenia / Q000276:immunology
D001323:Autoantibodies; D001789:Blood Group Antigens; D007518:Isoantibodies; D007626:Kell Blood-Group System