[Reaction of cytidylic acid with O-delta-aminooxybutylhydroxylamine].
The reaction of cytidylic acid with O-delta-aminooxybuthylhydroxylamine H2NO(CH2)4ONH2 (delta-HA) was studied. The reaction occurs in agreement with the mechanism of the cytidine and hydroxylamine or O-methylhydroxylamine interaction and results in appearance of two compounds: 4-O-delta-aminooxybuthyloxyme of 6-O-delta-aminooxybuthoxyamino-5,6-dihydrouridine-5'-phosphate and 4-O-delta-aminooxybuthyloxyme of uridine-5'-phosphate. These products are produced in pure form by gel-chromatography and these structures are evidenced by UV- and PMR-spectroscopy and by reaction with acetone. The kinetics of correspondent reaction was studied by UV-spectroscopy.
D055598:Chemical Phenomena; D002621:Chemistry; D003568:Cytidine Monophosphate; D003597:Cytosine Nucleotides; D006898:Hydroxylamines; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
D003597:Cytosine Nucleotides; D006898:Hydroxylamines; C035006:O-delta-aminooxybutylhydroxylamine; D003568:Cytidine Monophosphate
Produkty vzaimodeĭstviia tsitidilovoĭ kisloty s O-del'ta-aminooksibutilgidroksilaminom.