Factors influencing the success of artificial insemination.
Factors influencing the probability of conception following artificial insemination with donor semen (AID) have been investigated in a series of 124 married females. Overall, 79 conceptions were achieved, for a cumulative rate of conception of 85.1% at the end of 1 year and an average fecundability of 15%, using life-table analysis. Women aged 30 or over or those with evidence of tubal or ovulatory problems had decreased probability of conception, although not to a significant extent. Women whose husbands were azoospermic had 20% fecundability in response to AID, significantly better than the 10% fecundability after AID observed in the women whose mates were oligospermic. Cycles during which AID was successful were significantly more likely to have had a positive postcoital test observed, compared with unsuccessful AID cycles.
D000328:Adult; D000367:Age Factors; D001831:Body Temperature; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D007316:Insemination, Artificial, Heterologous; D008297:Male; D011247:Pregnancy; D011379:Prognosis