Tuberculosis and lung cancer risk in nonsmoking women.
We ascertained prior pulmonary tuberculosis infection in 211 non-Caucasian female lung cancer patients and 419 sex, race, ape, smoking history and birthplace-matched control subjects by searching the Hawaii State Tuberculosis Branch patient records. Among never-smokers we found a significant increase in risk associated with prior tuberculous infection (odds ratio, 8.2; 95% confidence limits = 1.3 to 54.4). No such association was found among smokers. Prior tuberculous infection was identified in only 5.5% of never-smoking lung cancer patients, however, suggesting that this factor is a relatively unimportant contributor to the etiologic aspects of lung cancer in persons who have never smoked.
D002681:China / Q000208:ethnology; D005260:Female; D006254:Hawaii; D006801:Humans; D007564:Japan / Q000208:ethnology; D008175:Lung Neoplasms / Q000150:complications / Q000453:epidemiology*; D012306:Risk; D012907:Smoking; D014397:Tuberculosis, Pulmonary / Q000150:complications*