Relationship between foreign H-2-like antigens on MCG4 sarcoma and the in vivo rejection of this tumor by syngeneic and semisyngeneic mice.
MCG4, a BALB/c sarcoma (H-2d), that abnormally expresses H-2k and h-2b-like antigens, regressed spontaneously when inoculated in BALB/c and in BALB/c hybrids F1. A relationship was found between the anti-H-2k and/or anti-H-2b activity detected in the sera and spleen cells of the regressor mice and their capacity to reject the tumor.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000276:immunology; D000951:Antigens, Neoplasm / Q000276:immunology*; D003433:Crosses, Genetic; D006084:Graft Rejection; D006183:H-2 Antigens / Q000276:immunology*; D007157:Immunologic Surveillance; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D012513:Sarcoma, Experimental / Q000276:immunology*
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D006183:H-2 Antigens