Renal function during acute and long term pindolol treatment in hypertensive patients with normal and decreased glomerular filtration.
1 In an acute study in hypertensive patients with normal and decreased renal function the i.v. administration of pindolol (0.1 mg/kg) caused a decrease in inulin clearance and a concomitant but not significant decrease in PAH clearance with a constant filtration fraction. 2 The long-term administration of pindolol (5--20 mg/day) to hypertensive patients with normal renal function was not associated with changes in renal function but in patients with a decreased renal function, pindolol caused an increase in PAH clearance but no change in inulin clearance.
D000284:Administration, Oral; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007275:Injections, Intravenous; D007674:Kidney Diseases / Q000139:chemically induced* / Q000503:physiopathology; D010869:Pindolol / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors
D010869:Pindolol