Hepatitis following cimetidine administration.
There have been only two reports of cimetidine-induced hepatitis. Such a low incidence suggests a hypersensitivity type of reaction. The case of an adult who developed both hepatic dysfunction and an impaired macrophage migration after exposure to cimetidine is discussed.
D000368:Aged; D002464:Cell Migration Inhibition; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000209:etiology*; D002927:Cimetidine / Q000009:adverse effects* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000276:immunology; D004381:Duodenal Ulcer / Q000188:drug therapy; D006146:Guanidines / Q000009:adverse effects*; D006801:Humans; D008264:Macrophages / Q000276:immunology; D008297:Male; D008655:Mesterolone / Q000627:therapeutic use; D000637:Transaminases / Q000032:analysis
D006146:Guanidines; D008655:Mesterolone; D002927:Cimetidine; D000637:Transaminases