Flurbiprofen in dysmenorrhea.
Reports on the efficacy of flurbiprofen for dysmenorrhea conflict. We gave 59 dysmenorrheic patients flurbiprofen (50 mg), aspirin (650 mg), or placebo. Paired drug comparisons showed that patients preferred flurbiprofen and that it was more effective in relief of pain, in allowing patients to pursue normal daily function, and in reducing the need for additional analgesics. Except in patient preference, aspirin was only marginally superior to placebo, There was an increase in minor side effects in the flurbiprofen group, but our results indicate therapeutic utility for flurbiprofen in dysmenorrhea.
D000293:Adolescent; D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D004341:Drug Evaluation; D004412:Dysmenorrhea / Q000188:drug therapy*; D005260:Female; D005480:Flurbiprofen / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D011422:Propionates / Q000627:therapeutic use*
D011422:Propionates; D005480:Flurbiprofen; D001241:Aspirin