[Effects of fenoterol on blood pressure, heart rate, and cardiotocogram of hypertensive and normotensive women in advanced pregnancy (author's transl)].
Two doses of fenoterol (Partusisten), a beta-mimetic drug were administered by continuous intravenous infusion over 90 minutes to 20 women in advanced pregnancy, ten of them with hypertension and the other ten with normal blood pressure. Blood pressure and maternal heart rate were measured in two-minute intervals. Foetal heart rate, short term irregularity, accelerations, and foetal movements were recorded by external cardiotocography. Decrease in diastolic blood pressure in response to fenoterol in pregnant women with hypertension was more strongly pronounced than it was in normotensive women. Hence, mean pressure was reduced in the first group. while the rise in maternal heart rate was one and the same in either group. While foetal heart rates went up in both groups. the rise started earlier and with higher intensity in the normotensive group. Pregnant women with normal blood pressure also exhibited a trend to more foetal movements. Short term irregularity and area of accelerations and acceleration remained unchanged in both groups.
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D004562:Electrocardiography; D004983:Ethanolamines / Q000494:pharmacology*; D005260:Female; D005280:Fenoterol / Q000494:pharmacology* / Q000627:therapeutic use; D005318:Fetal Heart / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011263:Pregnancy Trimester, Third; D014590:Uterine Contraction / Q000187:drug effects
D004983:Ethanolamines; D005280:Fenoterol
Der Einfluss von Fenoterol auf Blutdruck, Herzfrequenz und Kardiotokogramm bei hyper- und normotensiven Spätgraviden.