[Use of clomiphene in congenital adrenal cortical dysfunction].
The study of the functional state of the hypothalami-hypophyseal-ovarian system, using dexamethazone and clomiphene tests, has shown its ability to release gonadotropic hormones in response to stimulation and maintained relationship between the hypothalamus, hypophysis and ovaries in patients with congenital adrenocortical dysfunction. Further clomiphene administration was effective in patients, who suffered from congenital adrenocortical dysfunction with disturbed ovarian function, in spite of glucocorticoid treatment.
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis / Q000188:drug therapy*; D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D010053:Ovary / Q000187:drug effects; D010062:Ovulation Induction; D013997:Time Factors
D005938:Glucocorticoids; D002996:Clomiphene; D003907:Dexamethasone
Primenenie klomifena pri vrozhdennoĭ disfunktsii kory nadpochecknikov.