[Effect of small dispersed iron powder on the physico-chemical properties of mouse liver lipids].
The changes in the number of natural antioxidants, antioxidative activity, lipid peroxidation products, composition and oxidizing capacity of mouse liver lipids induced by subcutaneous injection of small dispersed iron powder (2 mg/kg) were investigated. During the first 6 hours following the injection the number of natural antioxidants, the antioxidative activity and lipid-oxidizing capacity are decreased, while the number of lipid hydroperoxides is increased, i.e. Fe exerts prooxidant effects on the lipids. All the changes in the physico-chemical parameters of the lipids under study are phasic and time-consuming. A direct correlation between the changes in the oxidizing capacity of the lipids and the content of natural oxidants in the lipids induced by injections of small dispersed iron poweder was established.
D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D007501:Iron / Q000494:pharmacology*; D007700:Kinetics; D050356:Lipid Metabolism; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D011208:Powders
D000975:Antioxidants; D008054:Lipid Peroxides; D011208:Powders; D007501:Iron
Vliianie melkodispersnogo poroshka zheleza na fiziko-khimicheskie kharakteristiki lipidov pecheni mysheĭ.