Congenital aneurysms adjacent to the anuli of the aortic and/or mitral valves.
The unusual occurrence of non-infected submitral and aortic aneurysms developing sequentially in an adult prompted us to review the pathogenesis of congenital aneurysms adjacent to the aortic and mitral valves. The findings support the suggestion that subvalvular aneurysms, like aortic sinus aneurysms, are a result of a congenital defect at the valve anulus. Submitral aneurysms occur only subjacent to the posterior leaflet. Whereas aortic sinus aneurysms may arise from any of the three sinuses, subaortic aneurysms occur only under the intermediate portion of the left aortic sinus. In the absence of rupture, the clinical presentation of these aneurysms results from valvular insufficiency or compression of the left coronary artery or of the conduction system.
D001014:Aortic Aneurysm / Q000151:congenital* / Q000473:pathology; D001021:Aortic Valve / Q000002:abnormalities; D006322:Heart Aneurysm / Q000151:congenital* / Q000473:pathology; D006801:Humans; D008943:Mitral Valve / Q000002:abnormalities