Corticosteroid-induced ocular hypertension. I. Prevalence in closed-angle glaucoma.
Forty-eight eyes with closed-angle glaucoma and 31 eyes at risk were subjected to corticosteroid provocative tests. 65% and 9.7% respectively responded with a change in pressure greater than or equal to 6 mmHg. The responses of the 2 groups were compared with each other and also with the corticosteroid pressure response in normal eyes. The differences in behaviour between the eyes with closed-angle glaucoma and eyes at risk, and the eyes with closed-angle glaucoma and normal eyes, are statistically highly significant. The implication of this are discussed. The prevalence of corticosteroid-induced ocular hypertension in closed-angle glaucoma is higher than previously reported.
D000368:Aged; D003907:Dexamethasone; D005260:Female; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D012306:Risk; D013268:Stimulation, Chemical
D003907:Dexamethasone