Frequency of Candida albicans serotypes in patients with denture-induced stomatitis and in normal denture wearers.
A comparison has been made between the serotypes of oral Candida albicans taken from patients  with denture-induced stomatitis and from a group of age and sex-matched controls. C albicans isolates were obtained from the fitting surface of the denture, the palatal mucosa supporting the denture, and the buccal mucosa. Twenty-nine of the 30 patients samples in the group affected by denture-induced stomatitis had only C albicans serotype A on their palatal mucosa and denture surface, while mixtures of serotypes were obtained from the buccal mucosa of these patients. Only one patient had serotype B isolates from the palatal mucosa and denture surface. In contrast, the control group had mixture of A and B serotypes from both the denture surface and the palatal mucosa, as well as from the buccal sites sampled. It would appear from these results that denture-induced stomatitis is associated with the proliferation of a single C albicans serotype, usually serotype A.
D002180:Candidiasis, Oral / Q000382:microbiology*; D003824:Denture, Complete / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D012703:Serotyping; D013280:Stomatitis / Q000382:microbiology*; D013282:Stomatitis, Denture / Q000382:microbiology*