Diazepam impairs lateral position control in highway driving.
Nine expert drivers operated an instrumented vehicle in tests over a highway at night after being treated with diazepam (5 and 10 milligrams), a placebo, and nothing. They reacted to 10 milligrams of diazepam with increased lateral position variability. Potentially dangerous impairment was inferred from the reactions of some subjects.
D000328:Adult; D001334:Automobile Driving; D003975:Diazepam / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D007839:Functional Laterality; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects*; D010919:Placebos
D010919:Placebos; D003975:Diazepam