Es-6, a further polymorphic esterase in the rat.
A further polymorphic rat esterase with broad tissue expression and restricted substrate specificity is described and tentatively called Es-6. Inbred rat strains have either fixed allele Es-6F or fixed allele Es-6S. Es-6 is not linked to the established esterase cluster consisting of the eight esterase loci Es-1, Es-2, Es-3M, Es-4M, Es-4W, Es-5 (= Es-3W), Es-7, and Es-8 in LG V of the rat or to RT1, Gc, c, a, and h. Esterases with apparently identical biochemical and genetical characteristics are Es-17 of the mouse and Es-A4 of humans.
D000483:Alleles; D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004950:Esterases / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D010053:Ovary / Q000201:enzymology; D011110:Polymorphism, Genetic; D051381:Rats / Q000235:genetics*; D013379:Substrate Specificity; D013737:Testis / Q000201:enzymology
D004791:Enzyme Inhibitors; D004950:Esterases