Novel pyrene-containing organophosphates as fluorescent probes for studying aging-induced conformational changes in organophosphate-inhibited acetylcholinesterase.
D000110:Acetylcholinesterase; D000818:Animals; D001665:Binding Sites; D002800:Cholinesterase Inhibitors; D004593:Electrophorus; D004793:Enzyme Reactivators; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D066298:In Vitro Techniques; D007700:Kinetics; D010755:Organophosphates / Q000138:chemical synthesis / Q000494:pharmacology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D011487:Protein Conformation; D011721:Pyrenes / Q000138:chemical synthesis / Q000494:pharmacology*; D013997:Time Factors
D002800:Cholinesterase Inhibitors; D004793:Enzyme Reactivators; D005456:Fluorescent Dyes; D010755:Organophosphates; D009943:Organophosphorus Compounds; D011721:Pyrenes; D000110:Acetylcholinesterase