Investigations on the synthesis and properties of new derivatives of methyl 3H-2-imino-7-methyl-4-oxopyrido [3,2-e]-1,3-thiazine-5-carboxylate.
Condensation of dimethyl 2-chloro-6-methylpyridine-3,4-dicarboxylate with thiourea and its N-substituted derivatives is described. It has been found that depending on the kind of substituents in the starting thiourea derivatives, pyrido [3,2-e]-1,3-thiazine or pyrido [2,3-d] pyrimidine derivatives were formed.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D000927:Anticonvulsants / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D006591:Hexobarbital / Q000494:pharmacology; D007928:Lethal Dose 50; D051379:Mice; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors; D012702:Serotonin Antagonists / Q000138:chemical synthesis*; D012890:Sleep / Q000187:drug effects; D013843:Thiazines / Q000138:chemical synthesis* / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D012702:Serotonin Antagonists; D013843:Thiazines; D012110:Reserpine; D006591:Hexobarbital