The influence of early weight-bearing on experimental total hip arthroplasties in dogs.
The bone-cement interface is an area of concern in the long-term fixation of endoprostheses. The effect of early weight-bearing on the interface has been discussed as an important parameter influencing the characteristics of the interface. In this study, a total hip arthroplasty was performed in two groups of six dogs each. One group was allowed immediate weight-bearing, while in the other, a knee disarticulation amputation was done to prevent weight-bearing. Three animals of each group were killed at three months and three of each group at six months, and a histological study of the interface was done. No morphologic difference was observed between weight-bearing and nonweight-bearing animals in the interface area. Endosteal bone remodeling occurred regardless of weight-bearing stresses. A fibrous membrane was found between the cement and the endosteal surface of the femur, and membrane thickness was similar in all animals. The membrane between the cement and acetabular bone, however, was consistently thicker. Quantitative studies revealed increased femoral cortical bone resorption in the nonweight-bearing animals.
D000077:Acetabulum / Q000473:pathology; D000818:Animals; D001843:Bone Cements; D001862:Bone Resorption / Q000473:pathology; D004285:Dogs; D004434:Early Ambulation; D005269:Femur / Q000473:pathology; D006622:Hip Prosthesis; D008297:Male; D008566:Membranes / Q000473:pathology; D011184:Postoperative Period
D001843:Bone Cements