[Results obtained on S. haematobium by Oltipraz in Niger (author's transl)].
Sixty-three outpatients shedding eggs of S. haematobium were treated with 35 mg/kg oltipraz given in two divided doses on a single day (Niamey). 75% of the patients were egg-negative at one month and 88.9% at three months. Urinary egg excretion was markedly reduced (98%) and the mean egg count per 10 ml urine decreased from 33 before dosing to 0.6 at two months. Oltipraz thus appears to be a most interesting drug for urinary schistosomiasis
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009548:Niger; D011719:Pyrazines / Q000627:therapeutic use*; D012548:Schistosoma haematobium; D012552:Schistosomiasis / Q000188:drug therapy*; D012556:Schistosomicides / Q000627:therapeutic use*; D013871:Thiones; D013876:Thiophenes
D011719:Pyrazines; D012556:Schistosomicides; D013871:Thiones; D013876:Thiophenes; C026209:oltipraz
Résultats obtenus sur S. haematobium par l'Oltipraz au Niger.