[Predictive value of 99m-Tc-Sn(II) methylene diphosphonate in the study of acute myocardial infarction].
Myocardial scintigraphy with 99mTc-Sn (II)-Methylenediphosphonate (MDP) was performed in 90 patients with proven acute myocardial infarction (AMI), and in 37 subjects with acute chest pain of a different etiology, during the first five days after the onset of their illness. The procedure was 82.2% sensitive, 86.5% specific, and 83.5 accurate for the diagnosis of AMI. Based on the usual clinical, electrocardiographic and biochemical criteria, the likelihood of AMI in this population was of 70.9% before the scintigraphic test. Application of Bayes' Theorem showed an increase in the likelihood of AMI, from 70.9% to 93.7%, when myocardial scintigraphy was positive, an incremental ruling-in-gain of 22.8%. A normal scintigraphy, on the other hand, reduced the likelihood of AMI, from 70.9% to 33.4%, an incremental ruling-out gain of 37.5%. It is concluded that myocardial scintigraphy with MDP is an important clinical procedure for the study of patients with acute chest pain: a positive test tends to confirm AMI, while a normal image, although it reduces the likelihood of this disease, is not particularly helpful in ruling it out.
D001499:Bayes Theorem; D004164:Diphosphonates; D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D010146:Pain / Q000175:diagnosis*; D011877:Radionuclide Imaging; D013667:Technetium; D013669:Technetium Tc 99m Medronate; D013909:Thorax
D004164:Diphosphonates; C023568:technetium Tc 99m (Sn)methylenediphosphonate; D013667:Technetium; D013669:Technetium Tc 99m Medronate
Los valores predictovos de la centelleografía con 99m Tc-Sn (II) metilendifosfonato en el estudio del infarto agudo del miocardio.