Genetic heterogeneity and population structure in north-west India.
Genetic markers consisting of 11 blood group and red cell enzyme systems were investigated in 14 endogamous groups of north-west India. Genetic differentiation among the samples as indicated by FST is appreciable, reflecting the ethnic diversity characteristic of this region. Local variation within each state is lower, indicating a geographical component to the total variation. This variation is refined by calculations of genetic distances, which show that the tribals and low-caste groups are closer together but well separated from high-caste Brahmins and other non-tribal middle castes. There is a slight possibility of disruptive selection, but the analyses suggest that the differences in genetic structure in north-west India are more likely to be due to their breeding structure, differential migration and ethnic affiliation.
D000483:Alleles; D001789:Blood Group Antigens / Q000235:genetics*; D003710:Demography; D004912:Erythrocytes / Q000201:enzymology; D005799:Genes, Dominant; D014644:Genetic Variation; D005826:Genetics, Medical; D005828:Genetics, Population; D006801:Humans; D007194:India; D007527:Isoenzymes / Q000235:genetics; D010641:Phenotype
D001789:Blood Group Antigens; D007527:Isoenzymes