[Changes in salivary immunoglobulin levels after cryosurgery of benign and malignant lesions of the oral cavity].
The authors have evaluated variations in salivary IgA, IgG, IgM levels after cryosurgical treatment of benign and malignant oral lesions. Salivary immunoglobulin levels were measured by radial immunodiffusion before a single cryotreatment 7 and 14 days after. Seven days after cryosurgery of the lesions, there was a statistically significant increase in salivary IgG and IgM levels (p less than 0,02). These results suggest that, at the time of maximal oral cavity inflammation, 7 days after cryotreatment, there was a transudation of these immunoglobulins from serum into saliva. Salivary IgA levels decrease in a significant way (p less than 0,02) on the 14th day; this behaviour seems to be strictly connected with tumor regression after cryosurgery.
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000601:surgery; D003452:Cryosurgery; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000276:immunology* / Q000601:surgery; D012463:Saliva / Q000276:immunology*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Variazioni del tasso delle immunoglobuline salivari dopo criochirurgia di lesioni benigne e maligne del cavo orale.