Ampliative medicament allergy: concomitant sensitivity to multiple medicaments including yellow soft paraffin, white soft paraffin, gentian violet and Span 20.
A patient developed multiple rare medicament contact allergies including sensitivities to gentian violet, yellow and white soft paraffin, and Span 20 (sorbitan monolaurate). Nickel sensitivity antedated these medicament allergies. The possibility that nickel sensitivity is a marker of predilection to develop multiple medicament allergies was tested. We were unable to demonstrate an increased incidence of nickel sensitivity in a group of patients with 2 or more medicament allergies.
D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D005260:Female; D005840:Gentian Violet / Q000009:adverse effects*; D006601:Hexoses / Q000009:adverse effects*; D006801:Humans; D009532:Nickel / Q000009:adverse effects; D010232:Paraffin / Q000009:adverse effects*; D012882:Skin Tests
D006601:Hexoses; C014822:sorbitan monolaurate; D009532:Nickel; D010232:Paraffin; D005840:Gentian Violet