[Megaloblastic maturation disorder of erythropoiesis in plasmacytoma and chronic lymphatic leukemia].
Quantitative and qualitative investigations of the erythropoiesis in the sternal marrow of untreated 52 patients with a plasmacytoma and 46 patients with a chronic lymphatic leukaemia resulted in about half the cases in an indicated or more distinct megaloblastic disturbance of maturation in a part of the erythroblasts. These changes of the erythroblastic cells might be the expression of a neoplastic transformation and of a disturbance of the differentiation of the pluripotent stem cells in these diseases.
D000368:Aged; D000748:Anemia, Macrocytic / Q000150:complications*; D000749:Anemia, Megaloblastic / Q000150:complications*; D001856:Bone Marrow Examination; D002471:Cell Transformation, Neoplastic; D004920:Erythropoiesis; D005260:Female; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010954:Plasmacytoma / Q000150:complications*
Megaloblastische Reifungsstörung der Erythropoese beim Plasmozytom und der chronischen lymphatischen Leukämie.