The influence of aging on intestinal absorption of vitamin B12 and niacin in rats.
The intestinal absorption of doses of vitamin B12 and of niacin was examined in 6, 12, and 24 months old female Wistar rats. Rats were dosed via stomach tube with radioactive forms of the vitamins and were killed 16 hours later. Percent of the dose remaining in the stomach and gastrointestinal tract and in the collected feces was determined. Absorption of the two vitamins was not influenced by the age of the animals.
D000284:Administration, Oral; D000375:Aging; D000818:Animals; D005260:Female; D007408:Intestinal Absorption; D009539:Nicotinic Acids / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014805:Vitamin B 12 / Q000378:metabolism*
D009539:Nicotinic Acids; D014805:Vitamin B 12