[Population-genetic examination of the glyoxalase I (GLO) red-cell isoenzyme system in the inhabitants of Szeged and its environment (South-Hungary) (author's transl)].
The authors have examined the gene frequency and phenotype distribution of GLO isoenzyme system in the blood samples from 1,288 randomized, unrelated persons and from 151 mother-child pairs by horizontal starch-gel electrophoresis. The observed gene frequencies (GLO1 = 0.3990, GLO2 = 0.6009) and phenotype distributions (GLO 1 = 18.1%; GLO 2-1 = 43.79%; GLO 2 = 38.20%) were in good accordance with that of the Caucasian population. The authors did not find any difference from the genetic model of two codominant alleles at an autosomal locus. The theoretical exclusion rate in paternity cases based on the GLO gene frequencies is 18.23%.
D000328:Adult; D002648:Child; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D006814:Hungary; D007527:Isoenzymes / Q000097:blood / Q000235:genetics*; D007791:Lactoylglutathione Lyase / Q000235:genetics*; D008190:Lyases / Q000235:genetics*; D008297:Male; D010334:Paternity; D010641:Phenotype
D007527:Isoenzymes; D008190:Lyases; D007791:Lactoylglutathione Lyase
Populationsgenetische Untersuchung des glyoxalase I (GLO)-Erythrozyten-Isoenzymsystems bein der Bevölkerung der Umgebung von Szeged (Süd-Ungarn).