A comparison of the cell-free protein synthetic activities of testicular tissue obtained from rats and mice of various ages.
1. The cell-free protein synthetic activity of the post-mitochondrial supernatant from the testes of 6-, 14-, and 30-month-old Sprague-Dawley rats and C57 B1/6J mice was determined. 2. An age-related decrease in cell-free protein synthesis was observed in both groups of rodents and was similar to the decrease previously reported for Fischer F344 rats. 3. The decrease in cell-free protein synthesis by testicular tissue from rodents occurs primarily after 14 months of age.
D000375:Aging; D000818:Animals; D007700:Kinetics; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D014176:Protein Biosynthesis; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains; D013737:Testis / Q000254:growth & development* / Q000378:metabolism