[Effect of the nutrient medium composition on biotin biosynthesis by an Actinomyces species 313-152 culture].
The effect of the composition of the nutrient medium on the biosynthesis of biotin by the culture Actinomyces species 313-152 was investigated. This microorganism can synthesize biotin on simple and complex media. The biotin synthesis is stimulated by oleic acid and Tween-80 utilized by the culture as a carbon source. The exogenous biotin added at concentrations of 1 x 10(-8) M to 1 x 10(-6) M to the medium containing fodder yeast hydrolyzate and Tween-80 did not inhibit the synthesis by the culture Actinomyces species 313-152.
D000190:Actinomyces / Q000187:drug effects / Q000378:metabolism*; D001710:Biotin / Q000096:biosynthesis*; D003470:Culture Media / Q000378:metabolism*; D019301:Oleic Acid; D009829:Oleic Acids / Q000378:metabolism; D011136:Polysorbates / Q000378:metabolism
D003470:Culture Media; D009829:Oleic Acids; D011136:Polysorbates; D019301:Oleic Acid; D001710:Biotin
Vliianie sostava pitatel'noĭ sredy na biosintez biotina kul'turoĭ Actinomyces species 313-152.