Toxic effects of chromium in a freshwater teleost fish, Channa punctatus.
The effect of in vivo exposure to a sublethal concentration of hexavalent chromium for 30 days on blood glucose, blood liver and muscle lactic acid; haemoglobin, liver and muscle glycogen; and activities of lactate dehydrogenase (LDH), pyruvate dehydrogenase (PHD) and succinate dehydrogenase (SDH) in liver, muscle, kidney, gills and brain has been studied. Blood glucose and lactic acid levels were elevated. Liver glycogen was depleted but muscle glycogen content increase. The activities of LDH and SDH in liver were elevate. Elevation was also observed in muscle LDH and PDH activities, showing that the rate of glycolysis is increased. No change was noted in haemoglobin content of blood or in the activities of the three dehydrogenases in kidney and gills.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002857:Chromium / Q000633:toxicity*; D005399:Fishes / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D013385:Succinate Dehydrogenase / Q000378:metabolism
D001786:Blood Glucose; D006454:Hemoglobins; D007773:Lactates; D011768:Pyruvate Dehydrogenase Complex; D002857:Chromium; D019344:Lactic Acid; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase