[Comparative study of 2 combined treatment regimens in stage-III to -IV ovarian cancer].
The results of the treatment of 75 patients with ovarian carcinoma of epithelial origin are reported. The authors give a randomised clinical comparison of the efficacy of two schemes of complex treatment of 54 patients with ascitic ovarian carcinoma and 21 patients with non-ascitic ovarian carcinoma. The first scheme included cytoxan chemotherapy plus surgery plus polychemotherapy (25 patients); the second--surgery plus polychemotherapy (29 patients). Patients with non-ascitic carcinoma (21) received the second type of treatment. Polychemotherapy consisted of two alternating schedules: 5 fluorouracil plus cyclophosphamide and hexamethylamine plus cyclophosphamide after a two week interval. Better results were obtained in the group of patients treated surgically at the initial stage of treatment.
D002369:Castration; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D011182:Postoperative Care / Q000379:methods; D011379:Prognosis; D013997:Time Factors
Sravnitel'noe izuchenie rezhimov kombinirovannogo lecheniia raka iaichnikov III-IV stadii.