Paradoxical increase in aminoglycoside body clearance in renal disease when volume of distribution increases.
D000617:Aminoglycosides / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D004285:Dogs; D005919:Glomerular Filtration Rate; D006801:Humans; D007674:Kidney Diseases / Q000378:metabolism*; D007700:Kinetics; D012756:Sheep
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents