The lipid composition of human testis in patients with bilateral varicocele as cause of infertility.
The lipid composition of human testis in patients with bilateral varicocele as cause of infertility is presented. The total lipids formed 1.90 percent of the total wet weight of the tissue. Testicular cholesterol formed 26.50 percent, glycerides 28.50 percent and phospholipids 45 percent of the total lipids. The increase observed in total cholesterol, glycerides in the testis of patients with bilateral varicocele compared to the control group appears to suggest that non-utilization of cholesterol esters for androgen biosynthesis. Androgen deficiency would result in inhibition of spermatogenesis as shown by the histological examination of the bilateral testicular biopsy specimens. Testicular neutral lipids get altered whenever there is imparied steroidogenesis and spermatogenesis. Thus, testicular lipids may taken as one of the important indices of testicular function.
D000328:Adult; D002784:Cholesterol / Q000378:metabolism; D005989:Glycerides / Q000378:metabolism; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D050356:Lipid Metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D013737:Testis / Q000378:metabolism*; D014646:Varicocele / Q000150:complications / Q000378:metabolism*
D005989:Glycerides; D010743:Phospholipids; D002784:Cholesterol