Cleavage of aspartyl beta-phenacyl esters by selenophenol under neutral conditions.
Neutral selenophenol in DMF accomplished the removal of the beta-phenacyl protecting group of aspartic acid in solution, on the peptide Boc-Asp (beta-OPac)- Phe amide and on the resin peptide Boc-Trp(Nin-For)-Met-Asp (beta-OPac)-P (CCK 30-33) without alpha, beta-rearrangement.
D001224:Aspartic Acid / Q000031:analogs & derivatives*; D001555:Benzene Derivatives; D002855:Chromatography, Thin Layer; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007202:Indicators and Reagents; D007931:Leucyl Aminopeptidase; D016566:Organoselenium Compounds; D012643:Selenium
D001555:Benzene Derivatives; D007202:Indicators and Reagents; D016566:Organoselenium Compounds; D001224:Aspartic Acid; C018846:benzeneselenol; D007931:Leucyl Aminopeptidase; D012643:Selenium