Does cervix conization increase the risk of complications in subsequent pregnancies?
In a series of 414 patients who underwent cervix conization because of cancer in situ, the risk of complications in subsequent pregnancies was analyzed by studying the outcome of their 923 pregnancies before and after cone biopsy. After conization the incidence of late spontaneous abortion was seven times higher than before. Moreover, 20.5% of pregnancies following cone biopsy required cervix cerclage because of suspected cervical insufficiency, or cesarean section because of a scarred cervix stenosis.
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D012306:Risk; D002581:Uterine Cervical Incompetence / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000601:surgery*