Iohexol compared to urografin meglumine in cerebral angiography. A randomized, double blind cross-over study.
In a double blind cross-over study the non ionic, water soluble contrast medium iohexol has been compared to Urografin Meglumine by angiography in common carotid artery and vertebral artery. More subjective adverse effects were generally seen with Urografin than with iohexol and statistically there were significantly less changes in heart rate after iohexol but no significant changes in the intra-arterial recorded blood pressure.
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D001921:Brain / Q000502:physiology; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine; D004311:Double-Blind Method; D005260:Female; D006339:Heart Rate; D006801:Humans; D007463:Iodobenzoates; D007472:Iohexol; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D014283:Triiodobenzoic Acids; D014711:Vertebral Artery / Q000000981:diagnostic imaging
D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D007472:Iohexol