[Prognosis of acute psychotropic drug poisoning. The Lausanne experience].
366 charts are reviewed of patients admitted to the ICU of the Lausanne University Department of Medicine during 5 consecutive years for psychotropic drug overdose and treated by supportive management. 25% were severely intoxicated and 46 patients required ventilatory support either for aspiration pneumonia or CNS depression. The mortality rate was 0.5% and mean stay in the ICU 2.8 days. Neither the two deaths nor the complications (already established upon admission or within 6 hours of presentation) could have been prevented by hemoperfusion. The efficiency of conservative management raises questions about the value of extrarenal clearance technics in the absence of concurrent renal failure.
D000328:Adult; D002037:Bundle-Branch Block / Q000139:chemically induced; D005260:Female; D006327:Heart Block / Q000139:chemically induced; D006439:Hemodynamics; D006801:Humans; D007040:Hypoventilation / Q000139:chemically induced; D007362:Intensive Care Units; D008297:Male; D008991:Monitoring, Physiologic; D011015:Pneumonia, Aspiration / Q000628:therapy; D011379:Prognosis; D011619:Psychotropic Drugs / Q000506:poisoning*; D012119:Respiration; D012121:Respiration, Artificial; D012125:Respiratory Center / Q000187:drug effects; D013557:Switzerland; D013610:Tachycardia / Q000139:chemically induced; D014882:Water-Electrolyte Balance
D011619:Psychotropic Drugs
Pronostic des intoxications aiguës par les psychotropes. Expérience lausannoise.