[Inducing action of hydrocortisone on mitotic rhythm in the epithelium of rat cornea and esophagus].
Circadian rhythms of mitoses were studied in the epithelium of the cornea and esophagus of rats given hydrocortisone. The hormone was injected daily during 7 days at 4-5 p.m., i.e. at the height of the blood glucocorticoid content within the circadian rhythm. The tissues of experimental rats, manifested biphasic rhythms of mitoses as compared with monophasic rhythms seen in intact animals. The amplitude and daily average magnitudes of the mitotic index were unchanged.
D000818:Animals; D002940:Circadian Rhythm / Q000187:drug effects; D003315:Cornea / Q000187:drug effects*; D004848:Epithelium / Q000187:drug effects; D004947:Esophagus / Q000187:drug effects*; D006854:Hydrocortisone / Q000494:pharmacology*; D008297:Male; D008938:Mitosis / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D006854:Hydrocortisone
Indutsiruiushchee deĭstvie gidrokortizona na ritm mitozov v épitelii rogovitsy i pishchevoda krys.