A method for monitoring drug effects on male sexual response: the effect of single dose labetalol.
1 A method for monitoring the effect of drugs on the genital response to stimulation provided by vibration is described. 2 Using this method, the effect on male sexual response of two oral doses (100 mg and 300 mg) labetalol were studied and compared with placebo in six subjects. 3 Labetalol did not affect the attainment or maintenance of erection. 4 Labetalol delayed ejaculation in a dose-related manner. 5 Labetalol treatment resulted in a significant dose-related delay in detumescence.
D004305:Dose-Response Relationship, Drug; D004983:Ethanolamines / Q000494:pharmacology*; D006801:Humans; D007741:Labetalol / Q000494:pharmacology*; D008297:Male; D009948:Orgasm / Q000187:drug effects*; D014732:Vibration
D004983:Ethanolamines; D007741:Labetalol