Chromosomal aberrations in Chinese hamster cells exposed in vitro to tritium-labelled thymidine or x-rays at--196 degrees C.
A comparison was made between the incidence of chromosomal aberrations in G2-phase first division Chinese hamster cells exposed to tritium labelled thymidine (dose range 54-522 rad) or to 250 kV X-rays (dose range 98-711 rad) at--196 degrees C. The dose-response relationship for chromatid aberrations, expressed as breaks per cell, appeared to be linear for intranuclear tritium whereas that for X-rays was curvilinear. For the dose range studied, cells exposed to X-rays were markedly less sensitive than tritium-incorporated cells where a transmutation effect may operate.
D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002875:Chromosomes / Q000528:radiation effects*; D003080:Cold Temperature; D006224:Cricetinae; D004307:Dose-Response Relationship, Radiation; D005260:Female; D007399:Interphase; D010053:Ovary; D012854:Sister Chromatid Exchange; D014316:Tritium; D014965:X-Rays
D014316:Tritium