Regional left ventricular ejection fraction from real-time two-dimensional echocardiography.
We studied regional left ventricular contraction patterns and ejection fraction from real-time two-dimensional echocardiograms in 8 normal subjects, 11 patients with coronary artery disease and 2 with congestive cardiomyopathy. The ventricle was divided into 12 regions and for each region, we calculated ejection fraction using a method which integrated the incremental volumes of a series of hemicylinders constructed within that region. The data obtained were displayed graphically to provide a detailed picture of regional ventricular function. Normal subjects had a uniform regional ventricular pattern (regional ejection fraction 54-74%). In patients with coronary disease, we found varying degrees of regional ventricular contraction abnormalities. In congestive cardiomyopathy global hypokinesis was present, and regional ejection fraction was reduced in all areas (11-39%). The study showed that two-dimensional echocardiography is a useful non-invasive bedside technique which may provide detailed quantitative information relating to regional left ventricular contraction abnormalities.
D000293:Adolescent; D000328:Adult; D002302:Cardiac Output; D003327:Coronary Disease / Q000175:diagnosis*; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006333:Heart Failure / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009203:Myocardial Infarction / Q000175:diagnosis; D009205:Myocarditis / Q000175:diagnosis; D013318:Stroke Volume