Assignment of the gene for cytosolic alanine aminotransferase (AAT1) to human chromosome 8.
The segregation of human cytosolic alanine aminotransferase (AAT1) and the individual human chromosomes has been studied in 27 secondary and tertiary rat hepatoma-human (liver) fibroblast hybrids. The staining solution used to visualize AAT activity on starch gels was specific for AAT since it was visualized only when all components of the stain were present. The locus for human AAT1 has been assigned to chromosome 8.
D000410:Alanine Transaminase / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D002906:Chromosomes, Human, 6-12 and X; D003600:Cytosol / Q000201:enzymology; D004592:Electrophoresis, Starch Gel; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000201:enzymology; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D008114:Liver Neoplasms, Experimental / Q000201:enzymology; D051381:Rats
D007527:Isoenzymes; D000410:Alanine Transaminase