Circadian variation of aldosterone urinary excretion in idiopathic hypertension.
Daily variations of the urinary aldosterone excretion have been studied in 8 hypertensive and in 4 normotensive women. The examined subjects did not receive any drug for at least two weeks before the study and were under the same standardized life-conditions. The urine samples were collected every 3 h for two consecutive days. Population mean cosinor analysis by Halberg did not yield a statistically significant rhythm of aldosterone urinary excretion in the hypertensive group. Further investigation of the temporal structure of the renin-angiotensin-aldosterone system is therefore necessary.
D000450:Aldosterone / Q000652:urine*; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008954:Models, Biological; D012016:Reference Values
D000450:Aldosterone