[Use of the conditioned avoidance reflex for detecting potential stimulants of higher nervous activity and their comparative characteristics].
Comparative research has been made of the influence of psychostimulants (amphetamine, sydnocarb, centedrin), neurotropic agents (neutrophil, mefexamide, tonibral, acephen), analeptics (ethimizole), alpha-adrenoblockers (pyrroxane), glutamine and its analogues on the forming in rats of the avoidance conditioned reflex in a Y-shaped labyrinth and its reproduction (repeated learning) after 24 hours. The time of learning, the number of mistakes and runnings until the criterion of learning is attained, emotional status, motor activity, elements of individual and group behavior of the animals have been studied to reveal the drugs having the most pronounced effect on the characteristics examined.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D003214:Conditioning, Classical / Q000187:drug effects*; D006613:Higher Nervous Activity / Q000187:drug effects*; D011619:Psychotropic Drugs / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical; D013997:Time Factors
D011619:Psychotropic Drugs
Ispol'zovanie oboronitel'nogo uslovnogo refleksa dlia vyiavleniia potentsial'nykh stimuliatorov vyssheĭ nervnoĭ deiatel'nosti i ikh sravnitel'noĭ kharakteristiki.