Normal viability of platelet concentrates obtained from CPDA-1 blood after storage in CL-3000 blood containers.
Platelet concentrates were obtained from blood anticoagulated with CPDA-1 and their viability after storage in CL-3000 containers for 72 h at 22 degrees C and for 24 and 48 h at 4 degrees C was studied using autologous reinfusion of 51Cr-labeled platelets. Yield and t1/2 values after such storage were similar to those previously reported for other containers and anti-coagulants. Survival of platelets stored at 22 degrees C for 3 days was essentially normal with the expected yields for that duration of storage. As has been described for other containers, adenine has no adverse or beneficial effect on platelet viability when assessed with these methods.
D000225:Adenine; D000925:Anticoagulants; D001792:Blood Platelets; D001793:Blood Preservation; D002470:Cell Survival; D002860:Chromium Radioisotopes; D006801:Humans; D013696:Temperature; D013997:Time Factors
D000925:Anticoagulants; D002860:Chromium Radioisotopes; D000225:Adenine