Positive and negative aggregation responses to cultured human tumor cell lines among different normal individuals.
Platelets from approximately 50% (7/16) of normal individuals have been shown to have greater sensitivity to aggregation induced by critical threshold concentrations of three human tumor cell lines. These results may have implications for the genetics and epidemiology of human neoplastic disease.
D000230:Adenocarcinoma / Q000503:physiopathology; D002460:Cell Line; D005910:Glioma / Q000503:physiopathology; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology; D008654:Mesothelioma / Q000503:physiopathology; D009369:Neoplasms / Q000503:physiopathology*; D009447:Neuroblastoma / Q000503:physiopathology; D010974:Platelet Aggregation; D012016:Reference Values