A new approach to compartmental analysis.
When recirculation of compounds and/or mixing transients are appreciable, traditional compartment analysis can lead to erroneous results. In this paper, a novel approach that overcomes many of these difficulties is presented. It unifies classical compartment analysis and indicator-dilution theory. It is conceptually simple and can be easily extended to many situations. Several examples for the case of a single compartment demonstrate the superiority of the suggested model to more traditional approaches.
D000818:Animals; D002451:Cell Compartmentation; D007444:Inulin / Q000097:blood; D008433:Mathematics; D008954:Models, Biological; D013997:Time Factors
D007444:Inulin