Myxoedema and Raynaud's phenomenon.
Cold hands is a common complaint in myxoedema and were reported by 15 of 17 patients before treatment of myxoedema with 4 having Raynaud's phenomenon. An increased cold sensitivity of the digital arteries could be demonstrated during finger cooling in about half of the patients and Raynaud's phenomenon was verified in the 4 patients as digital arterial closure. The cold sensitivity decreased significantly after treatment with L-thyroxine. The increased cold sensitivity in untreated myxoedema is probably due to an increased sympathetic discharge to the hands that might disclose a predisposition for Raynaud's phenomenon.
D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003080:Cold Temperature; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009230:Myxedema / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D011674:Pulse; D011928:Raynaud Disease / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D013974:Thyroxine / Q000627:therapeutic use
D013974:Thyroxine