Hypertensive crisis resulting from an MAO inhibitor and an over-the-counter appetite suppressant.
We present the case of a 28-year-old man being treated with Nardil for chronic depression who developed a hypertensive crisis and a severe occipital headache one hour after ingesting an over-the-counter appetite suppressant. The adverse reactions between MAO inhibitors and phenylpropanolamine and discussed, as are the dangers of using Demerol to treat the headache and Aldomet to treat the hypertension.
D000208:Acute Disease; D000328:Adult; D001067:Appetite Depressants / Q000009:adverse effects; D004347:Drug Interactions; D006261:Headache / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D008614:Meperidine / Q000627:therapeutic use; D008750:Methyldopa / Q000627:therapeutic use; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects*; D004366:Nonprescription Drugs; D010665:Phenylpropanolamine / Q000009:adverse effects*
D001067:Appetite Depressants; D008996:Monoamine Oxidase Inhibitors; D004366:Nonprescription Drugs; D010665:Phenylpropanolamine; D008750:Methyldopa; D008614:Meperidine