23, 25, 26-trihydroxycholecalciferol. A 25-hydroxycholecalciferol-26,23-lactone precursor.
(23S)-23,25-Dihydroxycholecalciferol was converted into at least five metabolites in kidney homogenates prepared from 1,25-dihydroxycholecalciferol-treated chickens. One of these has been positively identified as 23,25,26-trihydroxycholecalciferol by u.v.-absorbance analysis, mass spectrometry and chemical formation of derivatives. 23,25,26-Trihydroxycholecaciferol produces 25-hydroxycholecalciferol-26,23-lactone when incubated in chick kidney homogenates.
D000818:Animals; D002112:Calcifediol / Q000031:analogs & derivatives* / Q000378:metabolism; D002645:Chickens; D006887:Hydroxycholecalciferols / Q000378:metabolism*; D066298:In Vitro Techniques; D007668:Kidney / Q000378:metabolism*; D013058:Mass Spectrometry
D006887:Hydroxycholecalciferols; C026396:calcifediol lactone; C034128:23,25,26-trihydroxyvitamin D3; D002112:Calcifediol