Immunological monitoring of a patient with Guillain-Barré syndrome successfully treated with plasma exchange.
A patient with Guillain-Barré syndrome was successfully treated by plasma exchange (without any other therapy), and the relationship between changes in his peripheral blood lymphocyte subpopulations and the clinical improvement induced by plasma-pheresis was studied. At the recovery, the most interesting findings were an increase in T suppressor lymphocytes, and in Fc receptor-bearing lymphocytes (above normal values), together with a decrease in B lymphocytes. In this patient, plasma exchange not only removed toxic humoral factors, but also restored a normal balance among peripheral lymphocytes.
D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis; D006801:Humans; D008214:Lymphocytes / Q000145:classification; D008297:Male; D010951:Plasma Exchange; D011129:Polyradiculoneuropathy / Q000276:immunology* / Q000628:therapy
D000936:Antigen-Antibody Complex