[Microspectrophotometric method of studying the nuclear DNA of lymphoid cells in the lymph nodes in systemic blood diseases].
Basing on studies into nuclear DNA of lymphoid cells in histological sections of lymph nodes from patients with malignant non-Hodgkin's lymphoma, chronic lymphatic leukemia and myeloma, a modified scanning integrating digital microspectrophotometer enables one to differentiate between these diseases in terms of the content of nuclear DNA in lymphoid cells. The minimal content of nuclear DNA was found in malignant non-Hodgkin's lymphoma, the maximal during myeloma, with this content ranking intermediate in chronic lymphatic leukemia. The data obtained might be used as additional criteria in diagnosing the diseases in question.
D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D007945:Leukemia, Lymphoid / Q000032:analysis* / Q000175:diagnosis; D008198:Lymph Nodes / Q000032:analysis*; D008214:Lymphocytes / Q000032:analysis*; D008223:Lymphoma / Q000032:analysis* / Q000175:diagnosis; D009101:Multiple Myeloma / Q000032:analysis* / Q000175:diagnosis; D013053:Spectrophotometry / Q000379:methods*
D004273:DNA, Neoplasm
Mikrospektrofotometricheskiĭ metod issledovaniia iadernoĭ DNK limfoidnykh kletok limfaticheskikh uzlov pri sistemnykh zabolevaniiakh krovi.