Bowen's disease at the limbus.
Ten cases of Bowen's disease at the limbus have been clinicopathologically studied and followed up for 1 1/2 to 9 years. The clinical appearance might be classified into 3 principal forms; i.e., papillomatous, leukoplakic and gelatinous forms. However, histopathological differences could not be detected in the respective forms. In the follow-up study no recurrence was observed in the 8 cases treated with excision and cryotherapy, though recurrence and malignant change took place in one case of the remaining 2 cases, treated with excision only.
D000328:Adult; D000368:Aged; D001913:Bowen's Disease / Q000473:pathology* / Q000628:therapy; D002278:Carcinoma in Situ / Q000473:pathology / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000628:therapy; D003316:Corneal Diseases / Q000473:pathology* / Q000628:therapy; D003452:Cryosurgery; D005134:Eye Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis