[Size of the area of test-culture growth suppression with polyene antibiotic diffusion into the infected gel as a function of time].
The process of inhibition growth zone formation due to diffusion of polyenic antibiotics into inoculated gel was studied. Variability of the zone size with time was traced as a continuation of the mathematical model of zone formation described earlier. Differences in the zone size variability are shown in case the drug inactivation level is so low that it may be neglected and in case the drug inactivation level is considered. An equation for determination of the maximum zone size for the latter case is presented. The experimental data qualitatively correlate with the theoretical propositions and may be explained within the frames of the mathematical models used.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D004058:Diffusion; D005782:Gels; D008433:Mathematics; D008954:Models, Biological; D011090:Polyenes / Q000494:pharmacology*; D013997:Time Factors
D000900:Anti-Bacterial Agents; D005782:Gels; D011090:Polyenes
Razmer zony podavleniia rosta test-kul'tury pri diffuzii polienovykh antibiotikov v zarazhennyĭ gel' kak funktsiia vremeni.