Effects of common analgesics on the in vitro suppression of lymphocyte mitogen responses by cephalosporins.
Acetaminophen and indomethacin either did not alter or partially reversed the inhibition of lymphocyte mitogenic responses by cephalosporins. Aspirin at concentrations of >/=100 mug/ml in cultures containing cephalosporins reduced the response below the level with either drug alone.
D000082:Acetaminophen / Q000494:pharmacology; D000700:Analgesics / Q000494:pharmacology*; D001241:Aspirin / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology; D007700:Kinetics; D008214:Lymphocytes / Q000187:drug effects*; D008934:Mitogens / Q000494:pharmacology*; D010835:Phytohemagglutinins / Q000494:pharmacology
D000700:Analgesics; D002511:Cephalosporins; D008934:Mitogens; D010835:Phytohemagglutinins; D000082:Acetaminophen; D001241:Aspirin; D007213:Indomethacin