Aromatase enzyme catalysis is involved in the potent inhibition of estrogen biosynthesis caused by 4-acetoxy- and 4-hydroxy-4-androstene-3, 17-dione.
D000735:Androstenedione / Q000031:analogs & derivatives* / Q000494:pharmacology; D047072:Aromatase Inhibitors; D002384:Catalysis; D004967:Estrogens / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008861:Microsomes / Q000378:metabolism; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D013997:Time Factors
D047072:Aromatase Inhibitors; D004967:Estrogens; D000735:Androstenedione; C022569:4-acetoxy-4-androstene-3,17-dione; D010088:Oxidoreductases; C014594:formestane