Vaccination of broiler chicks from breeder flocks immunized with a live or inactivated oil emulsion Newcastle disease vaccine.
One-day-old chicks used in this study were from breeder flocks vaccinated with live (B1 and LaSota) or inactivated oil emulsion Newcastle disease (ND) vaccine. Chicks were vaccinated against ND by various procedures. The vaccination response was evaluated by hemagglutination-inhibition antibody titers and by challenge. Chicks from breeder flocks vaccinated with live virus vaccine had a geometric mean hemagglutination-inhibition antibody titer (GMT) for Newcastle of 7 (low maternal antibody titer) at 1 day of age, whereas those chickens derived from breeder flocks vaccinated with inactivated oil emulsion ND vaccine had a GMT of 84 (high maternal antibody titer). One-day-old chicks injected with live B1 vaccine were not immunized against ND regardless of breeder flock source. However, chickens with low maternal antibody titers were effectively immunized against ND when injected at 1 day of age with an inactivated or inactivated plus live ND vaccine. Chicks with high maternal antibody titers were not effectively protected when vaccinated with inactivated vaccine at 1 day of age; however, these chicks were protected when injected with a combined live and inactivated ND vaccine. Chicks from both breeder flocks were effectively immunized against ND when injected at 1 day of age with a live or inactivated ND vaccine and revaccinated by aerosol at 21 days of age with live B1 ND vaccine. Even though they were protected against ND, there appears to have been an interference phenomenon in chicks derived from breeder flocks vaccinated with the live ND vaccine. Beak-O-Vac vaccinated chickens were not effectively protected against ND when compared with chicks vaccinated by aerosol at 1 day of age. Water vaccination at 7, 14, or 21 days of age was as effective as aerosol vaccination when administered to chicks with low maternal antibody titers. However, water vaccination was not as effective as aerosol vaccination when administered to chicks with high maternal antibody titers.
D000284:Administration, Oral; D000336:Aerosols; D000818:Animals; D000831:Animals, Newborn; D000914:Antibodies, Viral / Q000096:biosynthesis; D002645:Chickens; D006385:Hemagglutination Inhibition Tests / Q000662:veterinary; D007279:Injections, Subcutaneous / Q000662:veterinary; D009521:Newcastle Disease / Q000517:prevention & control*; D009522:Newcastle disease virus / Q000276:immunology*; D014611:Vaccination / Q000379:methods / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
D000336:Aerosols; D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines