Effects of Etretinate on the neutrophil chemotaxis in pustular psoriasis.
The chemotactic activity and other functional parameters both granulocytic and seroimmunologic are evaluated in patients with pustular psoriasis before and after treatment with Etretinate. Before treatment these parameters, and in particular the chemotactic activity of neutrophil granulocyte do not reach statistical difference from control subjects. Etretinate determines in all the cases a dramatic and statistically significant reduction of the chemotactic activity of neutrophil chemotaxis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000187:drug effects; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*; D014212:Tretinoin / Q000031:analogs & derivatives*
D014212:Tretinoin; D005050:Etretinate