[Effects of acute ingestion of ethanol on several metabolic parameters (blood sugar, triglycerides, non-esterified fatty acids, lactic acid and uric acid) in subjects with type I diabetes mellitus].
7 diabetic type I patients and 17 normal subjects underwent to acute ethanol oral load (0,8 g/Kg), in order to investigate the modifications produced on glucose, triglycerides, FFA, lactate and uric acid plasma values. Our results show basal differences between diabetics and controls in all these parameters; furthermore, acute ethanol ingestion produces no significant variations of blood glucose in both groups, a significant decrease in FFA levels, an increase of triglyceridemic levels, more evident in diabetics and an increase of lactate, earlier in normals. On the other hand, there is no significant modification in uric acid plasma levels in controls, whereas in diabetics there is an increase, probably due to more elevated lactacidemic values in the late phase of the test.
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D000431:Ethanol / Q000009:adverse effects*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007773:Lactates; D014280:Triglycerides; D014527:Uric Acid; D019344:Lactic Acid; D000431:Ethanol
Effetti dell'ingestione acuta di etanolo su alcuni parametri metabolici (glicemia, trigliceridemia, NEFAemia, lattacidemia, uricemia) in soggetti con diabete mellito di tipo I.