[Time course analysis of the effects of intrapeduncular injection of kainic acid on amygdaloid paroxysmal activity].
Intrapeduncolar intrapeduncolar entopeduncolar injection of kainic acid determines an early decrease of the evoked amygdaloid paroxysmal activity, and a later increase of the AD length. The diphasic effect of the injection of kainic acid into the entopeduncular nucleus is likely due to the structural analogy of this drug with a neuroexcitant amino acid, monosodium glutamate. The inhibitory role of the entopeduncolar nucleus on the paroxysmal phenomena evoked in the amygdala is emphasized.
D000818:Animals; D002415:Cats; D003655:Decerebrate State; D007276:Injections, Intraventricular; D007608:Kainic Acid / Q000008:administration & dosage* / Q000494:pharmacology; D008636:Mesencephalon; D011759:Pyrrolidines / Q000008:administration & dosage*; D013997:Time Factors
D011759:Pyrrolidines; D007608:Kainic Acid
Analisi temporale degli effetti dell' inoculazione entopeduncolare di acido kainico sull' attivita' parossistica amigdaloidea.