[PFC syndrome (persistent fetal circulation). Central cyanosis in a full-term newborn infant without congenital heart defect].
In a case report the main features of the PFC-syndrome (persistent fetal circulation) are demonstrated: 1. general central cyanosis, 2. pulmonary hypertension, 3. right-to-left shunting via foramen ovale and (or) ductus arteriosus. At postmortem analysis in some of these patients the muscular thickness of the pulmonary vessels was found to be increased: primary PFC-syndrome. Hypoxia, shock, and many pulmonary disturbances of the newborn can produce the clinical picture of "persistent fetal circulation": secondary PFC-syndrome. Under adequate therapy with O2-insufflation, vasodilatory drugs, and if necessary mechanical ventilation the prognosis in the majority of cases is good.
D003490:Cyanosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010547:Persistent Fetal Circulation Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D011247:Pregnancy; D011859:Radiography
PFC-Syndrom (Persistenz der fetalen Zirkulation). Zentrale Zyanose eines reifen Neugeborenen ohne angeborene Herzmissbildung.