[Immediate effects of dimenhydrinate on uterine contraction and the fetal cardiac rhythm during labor].
The effects of intravenous administration of 100 mg of dimenhydrinate (Gravol) were studied in 20 patients during active spontaneous labour. The uterine activity and the fetal heart rate were monitored by an invasive technique. After administration of the medication the uterine activity increases significantly, and in 20% of the cases decelerations in the fetal heart rate of the hypoxic type occurred. Because of its unpredictable effects, this drug should be used with care during labour.
D004111:Dimenhydrinate / Q000494:pharmacology*; D005260:Female; D005318:Fetal Heart / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D014590:Uterine Contraction / Q000187:drug effects*
D004111:Dimenhydrinate
Effets immédiats du dimenhydrinate sur la contraction utérine e le rythme cardiaque foetal durant le travail.