Pharmacologic effects of a nitrate coronary vasodilator on cardiac perfusion and function, measured semiquantitatively.
Peritrate (pentaerythritol tetranitrate), a nitrate coronary vasodilator, was capable of significantly increasing perfusion and function in ischemic heart muscle. The A2 image-processing computer with software developed by Burow was used to evaluate regional perfusion and segmental wall motion in six patients with ischemic areas in the myocardium. These image-processing techniques were satisfactory for evaluation of ischemic heart muscle.
D000368:Aged; D003326:Coronary Circulation / Q000187:drug effects*; D003327:Coronary Disease / Q000503:physiopathology; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D010417:Pentaerythritol Tetranitrate / Q000494:pharmacology*; D010477:Perfusion; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013318:Stroke Volume / Q000187:drug effects; D013793:Thallium
D011868:Radioisotopes; D010417:Pentaerythritol Tetranitrate; D013793:Thallium