Kinetics of reactions within single erythrocytes: studies by microspectrophotometry.
Single cell spectroscopy has been applied to red blood cells along three different lines of research: a) distribution of single hemoglobin components among different erythrocytes, b) chemical reaction with ligands and diffusion in the red blood cell c) dynamics of hemoglobin S aggregation in single red blood cell. The results reported here show, in general, the great possibilities of using single-cell spectroscopy in investigating complex integrated systems.
D000755:Anemia, Sickle Cell / Q000097:blood; D000818:Animals; D001665:Binding Sites; D002248:Carbon Monoxide / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D004913:Erythrocytes, Abnormal / Q000378:metabolism; D006451:Hemoglobin, Sickle / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D010100:Oxygen / Q000097:blood; D013057:Spectrum Analysis / Q000295:instrumentation; D014337:Trout
D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D002248:Carbon Monoxide; D010100:Oxygen