Forearm exercise increases plasma hypoxanthine.
Plasma hypoxanthine was measured in three normal subjects during aerobic forearm exercise. The comparative increase of hypoxanthine greatly exceeded that of ammonia or lactate. It is proposed that hypoxanthine production reflects ATP breakdown in muscle. The test may prove useful in the investigation of patients with metabolic muscle disease.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000641:Ammonia / Q000097:blood; D005542:Forearm / Q000502:physiology; D006801:Humans; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000097:blood*; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism; D005082:Physical Exertion
D007042:Hypoxanthines; D007773:Lactates; D019271:Hypoxanthine; D019344:Lactic Acid; D000641:Ammonia; D000255:Adenosine Triphosphate