Occurrence of lipoprotein-X associated with intravenous administration of lipid emulsion in adults.
The intravenous lipid emulsion, Intralipid, both in vivo and in vitro causes a false-positive lipoprotein-X (LP-X) by immunoelectrophoresis and the electrophoresis-polyanion precipitation (EPAP) technic. The in vivo phenomenon has been shown to occur in adults, previously reported only in neonates. The false-positive LP-X may persist in the blood stream for some time following cessation of administration of the "Intralipid". This phenomenon should be taken into consideration when interpreting results of LP-X tests by these technics. It also has been shown that the presence of apolipoprotein-C is not necessary for LP-X like cathodal mobility and precipitation by the EPAP technic of complexes of albumin and Intralipid.
D000328:Adult; D011232:Chemical Precipitation; D002779:Cholestasis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005217:Fat Emulsions, Intravenous / Q000032:analysis*; D006801:Humans; D007122:Immunoelectrophoresis; D008073:Lipoprotein-X / Q000097:blood*
D005217:Fat Emulsions, Intravenous; D008073:Lipoprotein-X