Membrane IgM of bovine lymphocytes.
The membrane immunoglobulins of peripheral blood lymphocytes (PBL) obtained from four bovine-leukemia-virus infected calves and from a normal cow were isolated and characterized. They were found to consist of an IgM exhibiting a mu-chain of an apparent molecular weight (AMW) of 95,000 daltons, which is 10,000 daltons more than found for the mu-chain of serum IgM. It thus seems that this is a property of membrane-bound IgM of bovine origin.
D000818:Animals; D002417:Cattle / Q000276:immunology*; D002418:Cattle Diseases / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007075:Immunoglobulin M / Q000276:immunology*; D007938:Leukemia / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D008970:Molecular Weight; D011947:Receptors, Antigen, B-Cell / Q000276:immunology*
D007075:Immunoglobulin M; D011947:Receptors, Antigen, B-Cell