Evaluation of urinary elimination of N-acetyl-beta-glucosaminidase in healthy volunteers treated with dibekacin or gentamicin.
The urinary excretion of N-acetyl-beta-glucosaminidase was studied in healthy subjects during and after treatment with aminoglycosides. In terms of this parameter dibekacin appeared to be less nephrotoxic than gentamicin.
D000118:Acetylglucosaminidase / Q000652:urine*; D000328:Adult; D003982:Dibekacin / Q000009:adverse effects / Q000494:pharmacology*; D005839:Gentamicins / Q000009:adverse effects / Q000494:pharmacology*; D006596:Hexosaminidases / Q000652:urine*; D006801:Humans; D007612:Kanamycin / Q000031:analogs & derivatives*; D007674:Kidney Diseases / Q000139:chemically induced; D008297:Male
D005839:Gentamicins; D003982:Dibekacin; D007612:Kanamycin; D006596:Hexosaminidases; D000118:Acetylglucosaminidase