Effects of bilateral and unilateral neocortical lesions on schedule-induced polydipsia in rats.
Fifteen adult female rats were subjected to one of the following surgical procedures: (1) bilateral neocortical ablation; (2) unilateral neocortical ablation; or (3) sham surgery. Following recovery, all rats were tested on a fixed-time 1-min food schedule for acquisition of schedule-induced polydipsia. Contrary to a previous report by Bigler, Fleming and Shearer [1], no attenuation of polydipsia was seen in either group of rats with neocortical damage.
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology*; D004326:Drinking; D004435:Eating; D005260:Female; D051381:Rats; D011919:Rats, Inbred Strains; D012055:Reinforcement Schedule