Hyperostosing meningiomas of the sphenoid ridge--clinical features, surgical therapy, and long-term observations: review of 49 cases.
Thirty-three patients with en plaque, 9 with en masse (but with extensive bone involvement), and 7 with recurrent hyperostosing meningiomas of the sphenoid ridge were operated on. All patients underwent large extradural resection of the base of the skull as well as extirpation of the intradural tumors or adjacent plaques. The periorbita was involved in 13 patients (26.5%). Seventeen patients (34.7%) needed reconstruction of the base of the skull. This was achieved with autogenous bone grafts. In all but 3 patients, invasion of the bone by meningiomatous tissue was demonstrated histologically. Operative mortality was 4%. Total removal was possible in 91% of the patients with meningiomas located at the pterion or middle third of the sphenoid ridge. More difficult was the total removal of meningiomas of the inner third or of the entire sphenoid ridge (47%). However, long-term results have proved to be satisfying. Early surgical therapy should always be considered as the treatment of choice for such meningiomas.
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008579:Meningioma / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D011859:Radiography; D013100:Sphenoid Bone