[Various amniotic studies in the assessment of fetal pulmonary maturity].
The need for knowledge concerning foetal pulmonary maturity has led biochemists to develop a number of techniques based upon knowledge of amniotic phospholipids. Study of these phospholipids of foetal pulmonary origin is possible using biochemical and physical methods. The former include the L/S (Lecithin/sphingomyelins) ratio, as well as the measurement of total lecithins, or the palmitic acid/stearic acid ratio (P/S). Physical methods are based upon surface tension (Clements test) or fluidity (measurement of microviscosity by polarization of fluorescence) properties of phospholipids. Combination of several reproducible, sensitive and reliable tests (E/S ratio, microviscosity, Clements test) provides adequate information concerning foetal pulmonary maturity.
D000653:Amniotic Fluid / Q000032:analysis*; D002845:Chromatography / Q000379:methods; D003720:Densitometry; D005325:Fetal Organ Maturity; D006801:Humans; D008168:Lung / Q000196:embryology*; D010169:Palmitic Acids / Q000032:analysis; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis*; D013109:Sphingomyelins / Q000032:analysis; D013229:Stearic Acids / Q000032:analysis; D014783:Viscosity
D010169:Palmitic Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D013109:Sphingomyelins; D013229:Stearic Acids
Etude critique de quelques tests amniotiques d'appréciation de la maturité pulmonaire foetale.