[The problem of preoperative radiotherapy of renal adenocarcinomas from the viewpoint of tumor biology].
Tumour biological examinations were carried out on 26 patients with pulmonary metastases of renal adenocarcinomas; growth functions were used to calculate the point in time at which metastases began to grow, in relation to the time of operation. The aim was to derive information on the indications for pre-operative radiation therapy. In 3 patients out of 26 (11.5%) there is an indication for pre-operative irradiation. For comparative clinical tests on the value of pre-operative irradiation a minimum of 871 patients are needed in each group for comparison to evaluate the 3-year survival rate and 489 patients to evaluate the 5-year survival rate in order to be certain of the positive effect of pre-operative irradiation with 1% statistical probability. Our examinations are to be considered as a model.
D000230:Adenocarcinoma / Q000401:mortality / Q000503:physiopathology / Q000532:radiotherapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy*; D008175:Lung Neoplasms / Q000556:secondary; D011300:Preoperative Care
Zum Problem der präoperativen Stahlentherapie renaler Adenokarzinome aus tumorbiologischer Sicht.