[Changes in rat behavior after glutethimide exposure in various stages of antenatal neurogenesis].
After administration to rats in a dose of 200-400 mg/kg on days 14 and 15 of the pregnancy the hypnotic drug glutethimide induces in the rat progeny variations in the orienting-motor activity, latent period of runnings and raises the frequency of urinations upon training in a maze. The effect of glutethimide on the orienting-motor behavior was seen only in the first generation of the animals and was absent from the second generation animals.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005865:Gestational Age; D005984:Glutethimide / Q000494:pharmacology*; D006613:Higher Nervous Activity / Q000187:drug effects; D008297:Male; D009420:Nervous System / Q000187:drug effects* / Q000196:embryology; D011247:Pregnancy; D051381:Rats; D011930:Reaction Time / Q000187:drug effects
D005984:Glutethimide
Izmenenie povedeniia krys posle vozdeĭstviia glutetimidom na stadiiakh antenatal'nogo neĭrogeneza.