[Protein turnover of subcellular rat liver fractions in a varying protein supply of the body].
Experiments on rats were made to study turnover and the content of total proteins of rat liver subcellular fractions under isocaloric diets with different amounts of protein. As a result of receiving low-protein diets (9 and particularly 4.5% as regards protein), the half-life of 14 C-lysine decreases apart from a certain reduction in the protein content in all the fractions. Upon unchanged protein content in respect of the control (18% protein), high-protein diet also leads to the half-life diminution. An increase in protein turnover by 4.5% as regards protein in the diet correlates with overall and specific activities of cytochromooxidase in the inner membranes of mitochondria.
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage*; D006207:Half-Life; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D014176:Protein Biosynthesis; D051381:Rats; D011919:Rats, Inbred Strains; D013347:Subcellular Fractions / Q000378:metabolism; D013997:Time Factors
D004044:Dietary Proteins
Obnovlenie belkov subkletochnykh fraktsiĭ pecheni krys pri razlichnom snabzhenii organizma belkom.