Molecular requirements of the active sites of the cholinergic receptors. XVIII-Correlation between activity and double bond position among cyclopentene derivatives.
Some cyclopentene derivatives lacking the oxygenated functions have been synthesized and tested as cholinergic compounds. Their good muscarinic potency seems to confirm that such compounds interact with a receptor area which is not coincident with that recognized by other cholinergic agents such as muscarine and deoxamuscarine.
D001665:Binding Sites / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D003517:Cyclopentanes / Q000378:metabolism / Q000494:pharmacology*; D011950:Receptors, Cholinergic / Q000187:drug effects* / Q000378:metabolism
D003517:Cyclopentanes; D011950:Receptors, Cholinergic