Chromosome changes in lymphocytes after occupational exposure to pentachlorophenol (PCP).
Chromosome analyses were carried out on peripheral lymphocytes from 22 male workers employed at a pentachlorophenol (PCP) producing factory. As compared with a group of 22 matched controls a small, but significant, increase in the frequency of dicentrics and acentrics was observed. There was no significant increase of sister-chromatid exchange (SCEs) in smoking PCP workers, as compared with smoking controls. Within the control group, smokers had a higher incidence of SCEs than non-smokers.
D000393:Air Pollutants / Q000009:adverse effects*; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D002733:Chlorophenols / Q000009:adverse effects*; D002869:Chromosome Aberrations; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000502:physiology*; D008297:Male; D010416:Pentachlorophenol / Q000009:adverse effects*; D012854:Sister Chromatid Exchange / Q000187:drug effects; D012907:Smoking
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D002733:Chlorophenols; D010416:Pentachlorophenol