Identification of the cap binding protein of influenza virus.
The presence of a cap binding protein in influenza virus PR8 has recently been demonstrated by photoaffinity labelling with the cap-analogue (gamma [3 2P]-[4-(benzoylphenyl)methylamido]-7-methylguanosine 5'-triphosphate). This paper describes the identification of the labelled protein using two-dimensional gel electrophoresis. The protein is shown to be PB2, the smaller of the two basic P proteins in the polymerase complex.
D002352:Carrier Proteins / Q000235:genetics*; D003432:Cross-Linking Reagents; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D007700:Kinetics; D009975:Orthomyxoviridae / Q000235:genetics*; D039381:RNA Cap-Binding Proteins; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics
D002352:Carrier Proteins; D003432:Cross-Linking Reagents; D039381:RNA Cap-Binding Proteins; D014764:Viral Proteins; D012321:DNA-Directed RNA Polymerases