Virus capping on mycoplasma cells and its effect on membrane structure.
The capping of mycoplasmavirus L3 on the surface of Acholeplasma laidlawii was investigated. In electron microscope studies we observed a reduced capping after treatment of the host cell with energy-blocking agents. Other drugs inhibiting ligand capping on eucariotic cells had no effect. Changes in membrane structure after virus adsorption were observed spectroscopically using the excimer fluorescence technique. The results are interpreted in terms of a lipid-protein phase separation in connection with virus capping.
D000128:Acholeplasma laidlawii / Q000502:physiology*; D001435:Bacteriophages / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology*; D003208:Concanavalin A / Q000494:pharmacology; D003571:Cytochalasin B / Q000494:pharmacology; D004705:Endocytosis; D004734:Energy Metabolism; D008560:Membrane Fluidity; D013050:Spectrometry, Fluorescence
D003208:Concanavalin A; D003571:Cytochalasin B