Cooperativity of enzymatic reactions and molecular aspects of energy transduction.
This theoretical article concerns the basic principles of enzymatic conversion at the molecular level. The high rate of enzymatic reactions can be explained by a concept of collective substrate conversion of a cooperative nature. The proposed mechanism of charge separation in electron transport includes two aspects: electron tunnelling and coupled proton transfer. Energy transduction in muscle contraction and oxidative phosphorylation is outlined.
D000818:Animals; D004579:Electron Transport; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008433:Mathematics; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism; D010084:Oxidation-Reduction; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption
D004798:Enzymes