'Loads' alert.
"Loads," a combination of glutethimide and codeine, are a relatively new form of drug abuse that is increasing in popularity in the Los Angeles area as a heroin-substitute. Preliminary findings based on interviews and treatment of a group of preferential Loads abusers seen over a one-year period suggest that this combination has a potential for serious intoxications and withdrawal complications. The common withdrawal symptoms include those produced by both a sedative-hypnotic and a major narcotic and necessitate a detoxification plan based on the pharmacologic rationale of the abused combination.
D000328:Adult; D002140:California; D003061:Codeine; D005260:Female; D005984:Glutethimide; D006801:Humans; D008658:Inactivation, Metabolic; D008297:Male; D010343:Patient Admission; D013375:Substance Withdrawal Syndrome / Q000209:etiology; D019966:Substance-Related Disorders / Q000150:complications / Q000453:epidemiology* / Q000628:therapy
D005984:Glutethimide; D003061:Codeine