Mathematical model of muscular fatigue. I. Metabolite level changes during exercises of different intensities.
To quantify muscular fatigue we study by a mathematical modelization the changes of the levels of ATP and various metabolites, and of the oxygen uptake with the intensity of a requested muscular exercise. The proposed model is consistent with the main phenomena experimentally observed during exercises; it allows also one to extrapolate these experimental results to any condition and to simulate exercise-complete and/or incomplete recovery cycles. The lactate kinetics allows one particularly to justify the empirical optimization of rest rhythms during exercises of long duration. Equations are solved using a 4th order Runge-Kutta method; computations are performed on an IRIS 80 CII computer.
D000255:Adenosine Triphosphate / Q000378:metabolism; D003201:Computers; D004734:Energy Metabolism; D005221:Fatigue / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007773:Lactates / Q000378:metabolism; D008954:Models, Biological; D009119:Muscle Contraction; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D005082:Physical Exertion
D007773:Lactates; D000255:Adenosine Triphosphate; D005947:Glucose