Two new slow-moving variants of human serum albumin.
Two new slow-moving variants of human serum albumin were found in members of two unrelated Japanese families. These variants, different from each other and from the slow-moving variants described previously, were designated albumin "Okinoerabu' and albumin "Akasaka'. The mode of inheritance of each variant was consistent with an autosomal codominant trait. A very rare type, homozygote for a variant, albumin "Okinoerabu', was also detected. The segregation data of albumin and Gc showed no discrepancy from the postulation of a linkage between these two loci.
D004587:Electrophoresis, Agar Gel; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007564:Japan; D008297:Male; D010375:Pedigree; D010641:Phenotype; D012709:Serum Albumin / Q000235:genetics* / Q000302:isolation & purification
D012709:Serum Albumin