Age resistance in bovine babesiosis: role of blood factors in resistance to Babesia bovis.
In vitro cultivation of Babesia bovis in erythrocyte cultures demonstrated that blood from young animals contains a factor(s) responsible for their resistance to severe babesiosis. This factor is independent of antibody, is present in the serum of all young animals tested, and is dialyzable. The presence of this factor results in inhibition of parasite multiplication and the eventual death of the parasite while inside the erythrocyte.
D000375:Aging; D000818:Animals; D001403:Babesia / Q000254:growth & development*; D001404:Babesiosis / Q000097:blood / Q000503:physiopathology*; D001790:Blood Physiological Phenomena; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000503:physiopathology*; D002478:Cells, Cultured; D004912:Erythrocytes / Q000469:parasitology; D007113:Immunity, Innate