Further studies on the interaction of ethanol and nicotine in the pregnant rat.
Because alcohol and cigarette smoking are considered to be deleterious to the fetus, the combined effect of ethanol and nicotine during pregnancy was investigated. Pregnant Sprague-Dawley rats receiving a liquid alcohol diet at moderate dose-levels from gestational day 1 through 12, and a continuous subcutaneous infusion of nicotine from gestational day 6 through 12, revealed no significant reproductive and developmental disturbances.
D000818:Animals; D004032:Diet; D004347:Drug Interactions; D004622:Embryo, Mammalian / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005327:Fetal Resorption / Q000188:drug therapy; D009538:Nicotine / Q000494:pharmacology*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
D000431:Ethanol; D009538:Nicotine