Development of sexual dimorphism in the suprachiasmatic nucleus of the rat.
Synapses develop at similar rates in the suprachiasmatic nucleus of rats of both sexes, but values are higher in male than in female animals from birth to maturity. Male-type development cannot be mimicked by neonatal androgenization but results suggest that female-type development can be induced by neonatal castration of males. The results suggested that both prenatal and postnatal androgens are essential to normal male development.
D000818:Animals; D002369:Castration; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012733:Sex Differentiation; D013493:Suprachiasmatic Nucleus / Q000187:drug effects / Q000502:physiology*; D013569:Synapses / Q000502:physiology; D013739:Testosterone / Q000494:pharmacology
D013739:Testosterone