Epithelial second malignant tumours in retinoblastoma survivors. A review and report of a case.
The first case of epidermoid carcinoma of the tongue found in a retinoblastoma survivors is described. The patient, 10-year-old girl, had been treated successfully for bilateral retinoblastoma 9 years earlier. According to the literature, second malignant epithelial tumours are, in contrast to mesenchymal tumours such as osteosarcoma, very rare in retinoblastoma survivors. Initially one eye of the patient was treated with irradiation using Stallard's disk (radioactive cobalt), but we consider that Stallard's disk was unconnected with the genesis of the carcinoma of the tongue.
D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary*; D005134:Eye Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D011379:Prognosis; D012175:Retinoblastoma / Q000401:mortality / Q000473:pathology*; D014062:Tongue Neoplasms / Q000473:pathology / Q000556:secondary*