[Characteristics of the immunological response in children to the administration of a live tissue-culture influenza vaccine].
Various immunological tests were used for comprehensive study of vaccination immunity at the cellular level in children inoculated with different strains of influenza A virus. The characteristics of cell-mediated immunity in children vaccinated with a live tissue culture oral influenza vaccine were first obtained. There was a direct relationship between a rise in virus-neutralizing antibody levels and values of blast-transformation reaction. The live tissue culture influenza vaccine was shown to produce in children a short-time decrease in reactivity of lymphocytes, most significant changes occurring in the T-subpopulation of lymphocytes.
D000284:Administration, Oral; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D002648:Child; D006801:Humans; D007111:Immunity, Cellular; D009980:Influenza A virus / Q000276:immunology; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000276:immunology*; D008213:Lymphocyte Activation; D010919:Placebos; D013997:Time Factors
D000914:Antibodies, Viral; D007252:Influenza Vaccines; D010919:Placebos
Osobennosti immunologicheskogo otveta deteĭ na vvedenie zhivoĭ tkanevoĭ grippoznoĭ vaktsiny.