Studies on prolactin. 46. Preferential cleavage of the Arg125-Leu126 peptide bond of ovine hormone with immobilized trypsin.
Insoluble trypsin has been shown to attack preferentially some peptide bonds of ovine prolactin, within the large disulfide loop. The peptide bond most susceptible to immobilized trypsin was identified as the Arg125-Leu126 of the ovine prolactin structure.
D000818:Animals; D001120:Arginine; D004800:Enzymes, Immobilized / Q000378:metabolism*; D007930:Leucine; D011388:Prolactin; D012756:Sheep; D013379:Substrate Specificity; D014357:Trypsin / Q000378:metabolism*
D004800:Enzymes, Immobilized; D011388:Prolactin; D001120:Arginine; D014357:Trypsin; D007930:Leucine