Radioautographic analysis of [14C]2-deoxyglucose uptake in hippocampal formation of the rat during enforced locomotor activity-induced theta.
The [14C]2-deoxyglucose ( [14C]2-DG) uptake in the hippocampal formation of the rat was studied following enforced locomotor activity-induced theta (M theta). M theta was found to be essentially associated with an increase in 2-DG uptake in the stratum oriens of the hippocampal CA1-CA2 areas. These data contrast with our previous findings that physostigmine-induced theta (I theta) is specifically associated with a decrease in 2-DG uptake in the stratum lacunosum moleculare of hippocampal CA1-CA2 areas. When both of our sets of radioautographic data are considered together, M theta and I theta appear to have a distinct neurophysiological basis.
D000818:Animals; D001345:Autoradiography; D001693:Biological Transport, Active; D002250:Carbon Radioisotopes; D003837:Deoxy Sugars / Q000378:metabolism*; D003847:Deoxyglucose / Q000378:metabolism*; D004569:Electroencephalography; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D009043:Motor Activity; D051381:Rats; D011919:Rats, Inbred Strains; D013826:Theta Rhythm
D002250:Carbon Radioisotopes; D003837:Deoxy Sugars; D003847:Deoxyglucose