Hexsyn trileaflet valve: application to temporary blood pumps.
A trileaflet valve, compression molded of Hexsyn rubber, was evaluated as a component in temporary blood pumps. A pair of valves was integrated into an LVAD which was tested in vitro and in vivo. The valve's hemodynamic performance was satisfactory and the blood compatibility was excellent in a three-week, in vivo experiment conducted to demonstrate performance in a short-term application. Hexsyn, which has excellent properties and produces high quality, complex components with ease of fabrication, offers a potential for low-cost blood pump valves.
D000475:Alkenes / Q000494:pharmacology; D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002417:Cattle; D005069:Evaluation Studies as Topic; D006350:Heart Valve Prosthesis / Q000191:economics; D006354:Heart, Artificial / Q000191:economics*; D008297:Male; D011108:Polymers / Q000494:pharmacology*; D013997:Time Factors; D014261:Tricuspid Valve
D000475:Alkenes; D001672:Biocompatible Materials; D011108:Polymers; C009889:hexsyn