Receptor interactions of imidazolines. Influence of ionization constant on the diffusion of clonidine and a series of structurally related imidazolidines into and out of the central nervous system.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002490:Central Nervous System / Q000378:metabolism*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003000:Clonidine / Q000008:administration & dosage / Q000378:metabolism*; D004058:Diffusion; D007093:Imidazoles / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012110:Reserpine / Q000494:pharmacology
D007093:Imidazoles; D012110:Reserpine; D003000:Clonidine