[Hereditary drusen of Bruch's membrane. I. Clinical and light microscopical study ].
The authors describe a family with autosomal-dominant inheritance of hereditary Bruch's membrane drusen. After the death of the proband who was kept under clinical observation with fluorescein-angiographic examination over a period of seven years, the authors obtained the bulbus for histopathologic study. Light microscopic changes in the boundary-line structures of the retina and choroid and the occurrence of an intraretinal membrane in the maculopapillary bunch area are described. This membrane is thought to represent a "predisciform stage" in the development of this hereditary dystrophy.
D000293:Adolescent; D000328:Adult; D002829:Choroid / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D010375:Pedigree; D014603:Uveal Diseases / Q000235:genetics
Hereditäre Drusen der Bruchschen Membran I. Klinische und lichtmikroskiopische Beobachtungen.