Immunological parameters in Alzheimer's pre-senile dementia.
Serum immunoglobulin levels and C3 and C4 complement concentrations were assayed and serum tested for the presence of autoantibodies in 17 patients with pre-senile Alzheimer's disease. The majority of patients showed  a reduced level of one or more of immunoglobulins IgG, IgA or IgM. No significant abnormality was found to indicate an autoimmune disorder.
D000368:Aged; D000544:Alzheimer Disease / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003704:Dementia / Q000276:immunology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007072:Immunoglobulin D / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged
D001323:Autoantibodies; D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007072:Immunoglobulin D; D007074:Immunoglobulin G; D007075:Immunoglobulin M