[Evaluation of an experimental rabies vaccine by the oral and intestinal route with inactivated vaccines, concentrated or non-concentrated].
Application of beta-propiolactone inactivated rabies vaccine prepared in bovine embryo kidney cells, concentrated or non concentrated, by intestinal or oral route resulted in antibody production in rats and cats. 80-100% of vaccinated rats were protected against challenge with street rabies virus. The same vaccines (lyophilized in gelatin capsules) stimulated antibody production in more than 50% (5/8) cats which received the vaccine by the oral route.
D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation; D002415:Cats; D002417:Cattle; D002478:Cells, Cultured; D005069:Evaluation Studies as Topic; D007408:Intestinal Absorption; D007668:Kidney; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000627:therapeutic use*; D051381:Rats
D011819:Rabies Vaccines
Evaluation d'une vaccination rabique expérimentale par la voie orale et intestinale avec des vaccins tues, concentrés et non concentrés.