[Specificity characteristics of estrogen interaction with the cytoplasmic receptors of the uterus and oviducts in green monkeys (Cercopithecus griseus)].
The specificity of interaction in Cercopithecus griseus uterus and oviduct cytosol receptor systems with 14 estrogenic substances has been characterized. It was shown that the activity of steroid-receptor interaction was mainly due to presence of hydroxyl groups in C3- and C17b-positions. The nearest environment of these functional groups in molecules affected also the affinity of steroids to the systems investigated. Analysis of the cytosol estrogen-receptor system specificity from Cercopithecus griseus, guinea pig, human uterus and oviduct showed the general pattern of the estrogen binding to the above-mentioned systems. Similarity was also noted between these Cercopithecus griseus and human estrogen-receptor systems.
D000818:Animals; D002521:Cercopithecus; D003593:Cytoplasm / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D004347:Drug Interactions; D045166:Estradiol Congeners / Q000378:metabolism*; D004967:Estrogens / Q000378:metabolism*; D005187:Fallopian Tubes / Q000378:metabolism*; D005260:Female; D011960:Receptors, Estrogen / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism*
D045166:Estradiol Congeners; D004967:Estrogens; D011960:Receptors, Estrogen
Kharakteristika spetsifichnosti vzaimodeĭstviia éstrogenov s tsitoplazmaticheskimi retseptorami matki i iaĭtsevodov zelenykh martyshek (Cercopithecus griseus).