[Ornidazole in digestive surgery and surgical intensive care (author's transl)].
The authors test the effectiveness of ornidazole in digestive surgery and surgical reanimation. They emphasize the increased frequency of anaerobic bacteria and the role of beta-lactamine and aminoside antibiotics in the selection of these pathogens. Ornidazole was used for a one year period as either a curative or prophylactic treatment. The product is very well tolerated. During the year the authors noted a decreased frequency of bacteroides bacteremia. They highly recommend the association of penicillin G in traumatology to fight gram negative anaerobic bacilli and numerous gram positive bacteria. The association with gentamycin is justified in the presence of an anaerobic gram negative digestive flora. The use of third generation antibiotics has often proved to be futile. It is recommended that they be reserved for the most resistant organisms seen in primary extra-hospital infections. The prescription of ornidazole must procede and follow the surgical eradication of focal intra-abdominal infections, especially if it is an infection of appendicular origine.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000517:prevention & control*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D006801:Humans; D009593:Nitroimidazoles / Q000008:administration & dosage*; D009950:Ornidazole / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D009593:Nitroimidazoles; D009950:Ornidazole
L'ornidazole en chirurgie et en réanimation chirurgicale.