Assessment of ileal function by abdominal counting of the retention of a gamma emitting bile acid analogue.
In eight patients without gastrointestinal complaints and 30 patients with various gastrointestinal disorders ileal bile acid conservation was assessed by oral administration of 75Se 23-selena-25-homocholic acid (SeHCAT) followed by abdominal gamma counting (SeHCAT-test). The results of the test correlated fairly well with the clinical features and with the [1-14C]-cholylglycine breath test including faecal 14C measurements (breath test). Of the two bile acid absorption tests the new is perhaps the more sensitive and is the one most easily performed.
D000328:Adult; D000368:Aged; D001647:Bile Acids and Salts / Q000378:metabolism; D001944:Breath Tests; D005260:Female; D005767:Gastrointestinal Diseases / Q000503:physiopathology*; D006801:Humans; D007082:Ileum / Q000503:physiopathology*; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D012588:Scintillation Counting; D013656:Taurocholic Acid / Q000031:analogs & derivatives*
D001647:Bile Acids and Salts; D013656:Taurocholic Acid; C033638:23-seleno-25-homotaurocholic acid