[Steroid-responsive nephrotic syndrome in infants: 2 familial case reports ].
Two cases of nephrotic syndrome discovered respectively at the ages of 3 and 7 weeks in 2 siblings are reported. Nephrosis was of the optically normal glomeruli-type in both cases. In spite of the very young age of the patients a good result of steroid-therapy was obtained after 6 and 8 weeks of treatment, respectively. Both children were not HLA-identical but had in common the A2-B12-DR4 haplotype.
D005260:Female; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis
D006680:HLA Antigens; D011241:Prednisone
Syndrome néphrotique infantile corticosensible. Deux observations familiales.