[Transformation of the cholinonegative effect of atropine to a cholinopositive one on denervated human salivary gland under reflex stimulation].
The possibility of inducing a special status of the salivary gland function has been demonstrated in 20 subjects with its denervation. This status is characterized by an immediate transformation of the cholinolytic response to atropine administration to the cholinomimetic one, extremely intense and durable, as a result of minimal reflex stimulation playing a role of the inducing agent.
D000328:Adult; D001285:Atropine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000008:administration & dosage*; D010277:Parasympathomimetics / Q000008:administration & dosage*; D010862:Pilocarpine / Q000008:administration & dosage; D012018:Reflex / Q000502:physiology*; D012469:Salivary Glands / Q000187:drug effects* / Q000294:innervation; D012472:Salivation / Q000187:drug effects
D010276:Parasympatholytics; D010277:Parasympathomimetics; D010862:Pilocarpine; D001285:Atropine
Prevrashchenie kholinonegativnogo éffekta atropina v kholinopozitivnyĭ na denervirovannoĭ sliunnoĭ zheleze cheloveka pri reflektornom razdrazhenii.