[Effectiveness of surgical and radiotherapeutic action on cervical carcinoma, stages I and II (T1 N0 M0 and T2 N0 M0). First communication].
Reported in this paper are therapeutic results obtained from 855 patients with cervical carcinoma, Category T1 (557 patients) and Category T2 (298 patients), between 1967 and 1976. -- Metastasization of lymph nodes was recorded from 9.9 per cent of the patients in Category T1 and from 18.4 per cent in T2. --Abdominal radical surgery (Wertheim's operation) was applied to 87.3 per cent, while vaginal radical surgery (modified according to Schauta) was performed on 8.2 per cent, and the socalled "minor Wertheim", a modification devised at the authors' hospital, to 4.5 per cent. Complementary postoperative irradiation was used on 497 of 855 patients, with 93.6 per cent of these patients receiving postoperative irradiation under orthovolt conditions and 6.4 per cent under telecobalt conditions. -- Five-year survival rates were 87.5 per cent without postoperative irradiation and 83 per cent with postoperative irradiation in Category T1 or 78.1 per cent without irradiation and 73.2 per cent with irradiation in Category T2. Survival rates declined by about 30 per cent in cases with lymph node metastases. Manifestation of local recurrence was found to be delayed by about one to one-a-half year by postoperative irradiation, an effect, however, which was no longer detectable after five years had passed. Differentiation of radiation doses had no bearings at all on healing. Adjuvant postoperative irradiation of patients in Category p T1 N0 M0 proved ineffective. Mortality following primary therapy amounted to 2.1 per cent. Morbidity accounted for 36.8 per cent of all patients, with due consideration being given to all intercurrent complications.
D000328:Adult; D000368:Aged; D005260:Female; D005859:Germany, East; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*
Zur Effektivität operativer und strahlentherapeutischer massnahmen beim Zervixkarzinom im Stadium I und II (T1 N0 M0 und T2 N0 M0).