Dibromodulcitol in the treatment of metastatic hemangiopericytoma.
Hemangiopericytoma is an uncommon sarcoma arising from the pericapillary cells. While the rarity of this lesion precludes randomized investigation, metastatic hemangiopericytoma has been noted to respond to a variety of agents, including vincristine, adriamycin, actinomycin, and high-dose methotrexate. We wish to report an unusual case of this disease which failed to respond to the above but then exhibited a marked response to dibromodulcitol. In light of the unusual nature of this response, we would like to suggest a controlled trial of the use of dibromodulcitol in patients with this rare tumor.
D000368:Aged; D005260:Female; D006393:Hemangiopericytoma / Q000188:drug therapy* / Q000556:secondary; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008936:Mitolactol / Q000627:therapeutic use*; D009362:Neoplasm Metastasis; D013848:Thigh
D008936:Mitolactol