[Lysozyme: basic facts and diagnostic importance].
The determination of lysozyme has been shown to be more relevant than assumed until now. It can be used as a marker in the therapy of acute and chronic urinary tract infections. The determination of lysozyme in cerebro spinal fluid and blood serum are helpful to differentiate between bacterial and aseptic meningitides or infections. Elevated fecal lysozyme excretion in adolescents are an indicator for a chronic inflammatory bowel disease. Control of fecal lysozyme excretion can be used as a marker for a relapse and to monitor therapeutic efficiency in patients with inflammatory bowel disease. A consistent high level of fecal lysozyme excretion in adults over the age of 40 is an indicator for possible colorectal tumors and warrants further thorough investigation.
D000293:Adolescent; D000328:Adult; D001500:BCG Vaccine / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis; D003110:Colonic Neoplasms / Q000201:enzymology; D003424:Crohn Disease / Q000201:enzymology; D003937:Diagnosis, Differential; D005243:Feces / Q000201:enzymology; D006801:Humans; D008264:Macrophages / Q000201:enzymology / Q000276:immunology; D008581:Meningitis / Q000175:diagnosis; D009000:Monocytes / Q000201:enzymology; D009113:Muramidase / Q000134:cerebrospinal fluid / Q000378:metabolism*
D001500:BCG Vaccine; D009113:Muramidase
Lysozym: Grundlagen und diagnostische Bedeutung.