[Coronary vascular reactions of dogs to hypothalamic stimulation in acute and chronic experiments].
Stimulation of emotiogenic zones of the dog hypothalamus in acute and chronic experiments evoked the same responses in the heart and coronary vessels: an increase of the coronary vessels resistance occurred within first 5 sec of the stimulation. Acceleration of cardiac activity involved coronary vessels dilatation. Hypothalamic stimulation against the background of adrenergic betareceptor block caused an increase of coronary vessels resistance alone. Changes of arterial pressure were the same as before the block, and the change of the heart rate was less obvious. The neurogenic vasoconstriction of coronary vessels and their metabolic vasodilatation are interrelated in a complicated way: adrenergic influences activating smooth muscles of coronary vessels maintain their extravascular effects during vasodilatation of metabolic nature.
D000818:Animals; D003331:Coronary Vessels / Q000187:drug effects / Q000502:physiology*; D004285:Dogs; D004558:Electric Stimulation; D006439:Hemodynamics / Q000187:drug effects; D007026:Hypothalamic Area, Lateral / Q000502:physiology; D007031:Hypothalamus / Q000187:drug effects / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D014655:Vascular Resistance / Q000187:drug effects; D014661:Vasoconstriction / Q000187:drug effects
D011433:Propranolol
Reaktsii koronarnykh sosudov u sobak pri razdrazhenii gipotalamusa v ostrom i khronicheskom opytakh.