[Identification of the antibiotic formed by a Str. canulus 106/78 culture with antibiotic CC-1065].
An antibiotic with a melting point of at least 340 degrees C, [alpha]D + 100 degrees (c 1 per cent in dimethylformamide) was isolated from the mycelium of Str. canulus 106/78. Calculated (%): C 60.63, H 4.69, N 13.6. The UV spectrum of the antibiotic (in methanol solution) showed the terminal absorption, shoulder at 265 nm and maximum at 375 nm. In dimethylformamide solution the UV absorption maximum was observed at 370 nm with E1 1% cm 845. The IR, FMR and 13C-NMR spectra of antibiotic 106 are analogous to the respective spectra of antibiotic CC-1065 which is indicative of their identity.
D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000096:biosynthesis; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D000080890:Duocarmycins; D007211:Indoles; D007933:Leucomycins / Q000032:analysis / Q000096:biosynthesis; D009682:Magnetic Resonance Spectroscopy; D012988:Soil Microbiology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000080890:Duocarmycins; D007211:Indoles; D007933:Leucomycins; C018782:CC 1065
Identifikatsiia antibiotika, obrazuemogo kul'turoĭ Str. canulus 106/78, s antibiotikom CC-1065.