[Structural differences of C-terminal fragment of the alpha-subunits of rabbit muscle aldolase in normal animals and in experimental atherosclerosis].
The COOH-terminal BrCN fragment of the aldolase alpha-subunit from muscles of rabbits in norm and under atherosclerosis was studied by the method of dansyl-fingerprints in a silicagel and polyamide thin layer. It is shown that under atherosclerosis the amount of peptides in the fragment under study increases and the topography of two of them changes. The content of lysine, serine and valine enhances in it. The results evidence for structural differences in C-terminal fragment of aldolase alpha-subunits in muscles of rabbits in norm and under experimental atherosclerosis.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001161:Arteriosclerosis / Q000201:enzymology*; D003488:Cyanogen Bromide; D004195:Disease Models, Animal; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology*; D010446:Peptide Fragments / Q000032:analysis; D011817:Rabbits
D000596:Amino Acids; D010446:Peptide Fragments; D005634:Fructose-Bisphosphate Aldolase; D003488:Cyanogen Bromide
O strukturnykh razlichiiakh C-kontsevogo fragmenta al'fa-sub"edinitsy al'dolazy myshts krolikov v norme i pri'eksperimental'nom ateroskleroze.