Determination of labetalol in a post mortem case using HPLC.
A case report involving low levels of labetalol is presented. Samples of post mortem stomach contents, liver, kidney, urine, and blood were flocculated with aluminium hydroxide before the labetalol was extracted by using Sep-pakTM C18 cartridges. Quantification of the extracts was performed by HPLC with an ultraviolet detector. The significant of relatively low drug levels found in a patient suffering from a respiratory disease is discussed.
D000368:Aged; D002102:Cadaver; D002851:Chromatography, High Pressure Liquid; D004983:Ethanolamines / Q000032:analysis*; D006801:Humans; D007741:Labetalol / Q000032:analysis* / Q000633:toxicity; D008297:Male
D004983:Ethanolamines; D007741:Labetalol