Leukoembolization in ocular vascular occlusion.
The occurrence of complement-induced white blood cell aggregation and embolization has previously been little suspected. This may be a mechanism which underlies certain occlusive vascular diseases. It is possible that the fundus picture which has been described as Purtscher's Retinopathy following severe trauma and acute pancreatitis may be explained by this mechanism. A further case of Purtscher's type Retinopathy associated with acute pancreatitis is reported.
D000208:Acute Disease; D000328:Adult; D003182:Complement C5 / Q000032:analysis / Q000502:physiology; D004617:Embolism / Q000150:complications*; D006801:Humans; D007962:Leukocytes; D008297:Male; D009896:Optic Atrophy / Q000209:etiology*; D010195:Pancreatitis / Q000150:complications*; D012164:Retinal Diseases / Q000209:etiology*; D014652:Vascular Diseases / Q000209:etiology
D003182:Complement C5