HLA antigens in Stevens-Johnson syndrome with ocular involvement.
Fifteen white patients and three black patients with Stevens-Johnson syndrome (SJS) with ocular involvement had HLA typing performed. The HLA-Bw44 antigen was found to have an increased frequency of 66.7% in white patients with SJS with ocular involvement, which was statistically significant when compared with a frequency of 20.4% in the white control population. The results of this study suggest that there is an immunogenetic susceptibility to the development of SJS with ocular manifestations in white patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D044383:Black People; D002648:Child; D002675:Child, Preschool; D005128:Eye Diseases / Q000235:genetics / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013262:Stevens-Johnson Syndrome / Q000235:genetics / Q000276:immunology*; D044465:White People
D006680:HLA Antigens