Studies on live attenuated mumps vaccine. III. Long-term follow-up study on the efficacy of Biken vaccine.
Clinical and serological follow-ups were made on 24 children for 8 years after immunization against mumps with attenuated mumps vaccine, Biken vaccine. To evaluate the protective efficacy of the vaccine, matched controls were studied during the same period. Serological examination revealed that 91% of the controls were infected with mumps and 83% of them contracted the disease during the studied period. However, none of the vaccinees developed clinical infection after close contact with mumps patients. There was no substantial decrease in the antibody titers in unexposed vaccines after vaccination.
D000914:Antibodies, Viral / Q000032:analysis; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan; D009107:Mumps / Q000453:epidemiology; D009108:Mumps Vaccine / Q000592:standards / Q000627:therapeutic use*; D014613:Vaccines, Attenuated / Q000627:therapeutic use
D000914:Antibodies, Viral; D009108:Mumps Vaccine; D014613:Vaccines, Attenuated