Effectivity of oral vaccination of foxes against rabies with Flury HEP strain 675.
A group of 14 adult foxes was orally vaccinated with 2 ml Flury HEP strain 675, titre 10(8.2 TCID50. Each fox seroconverted neutralizing antibody titres ranging between 1:40 and 1:640. These foxes survived an intramuscular challenge with 8000 mouse LD50 pathogenic rabies virus, whereas six out of seven unprotected control foxes died within 28 days. This study was accompanied by virus isolation, fluorescence microscopic examination and neutralization tests.
D000284:Administration, Oral; D000818:Animals; D005589:Foxes / Q000276:immunology*; D011818:Rabies / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000008:administration & dosage* / Q000627:therapeutic use; D011820:Rabies virus / Q000276:immunology; D013045:Species Specificity
D011819:Rabies Vaccines