[A comparison of cinoxacin and nalidixic acid in the treatment of chronic urinary tract infections].
A total of 60 patients with chronic urinary tract infections were included in this comparative study. 29 patients received cinoxacin and 31 nalidixic acid for a period of ten days. There were five therapy failures in the cinoxacin group and nine in the nalidixic acid group. Drug-related side-effects were reported by 11 patients in the cinoxacin group and by 13 patients in the nalidixic acid group. Gastrointestinal and central nervous disturbances were the adverse reactions which occurred most frequently. In all cases side-effects disappeared quickly after therapy was discontinued.
D001437:Bacteriuria / Q000188:drug therapy; D002908:Chronic Disease; D002937:Cinoxacin / Q000009:adverse effects / Q000627:therapeutic use*; D003556:Cystitis / Q000188:drug therapy; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D009268:Nalidixic Acid / Q000009:adverse effects / Q000627:therapeutic use*; D009422:Nervous System Diseases / Q000139:chemically induced; D011704:Pyelonephritis / Q000188:drug therapy; D011724:Pyridazines / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy*
D011724:Pyridazines; D009268:Nalidixic Acid; D002937:Cinoxacin
Vergleich von Cinoxacin und Nalidixinsäure bei der Behandlung von chronischen Harnwegsinfektionen.