[Toxic properties of rabbit and dog sera in controlled hyperthermia].
Toxic properties of rabbit and dog serum were studied in mice with reticuloendothelial system blockade under controlled hyperthermia. A study was also made of mast cell degranulation in rats during hyperthermia. The controlled hyperthermia led to the appearance of toxic properties that were more pronounced in rabbits. On heating the response of mast cell degranulation in rats got intensified. The toxic properties correlated with the rate of degranulation. The latter circumstance evidences the systemic pattern of the pathogenesis of hyperthermia.
D000818:Animals; D001831:Body Temperature; D004285:Dogs; D005334:Fever / Q000401:mortality / Q000503:physiopathology*; D007106:Immune Sera / Q000633:toxicity*; D008407:Mast Cells / Q000187:drug effects; D051379:Mice; D012157:Mononuclear Phagocyte System / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D013997:Time Factors
D007106:Immune Sera
Toksicheskie svoĭstva syvorotki krolikov i sobak pri upravliaemoĭ gipertermii.