Long-term evaluation of the treatment of Menière's disease with betahistine HCl.
Long-term evaluation of patients treated continuously for a period of 12-14 years with betahistine HCl shows a success rates of more than 80%. Many of these patients had various other kinds of therapy before betahistine HCl treatment to no avail. It seems to us that betahistine HCl is only a basic long-term treatment which has no habituation and still is active in controlling Menière's disease even after a long-term period. Other drugs such as antihistamine, phenothiazines, vitamins and tranquilizers only produce a symptomatic treatment. Betahistine HCl produces no modification or effect on the evolution of deafness.
D001299:Audiometry; D001621:Betahistine / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000188:drug therapy*; D011725:Pyridines / Q000627:therapeutic use*; D011897:Random Allocation; D013997:Time Factors; D014724:Vestibular Function Tests
D011725:Pyridines; D001621:Betahistine