The isolation and chemical characterization of skeletal muscle microsomes from swine susceptible to malignant hyperpyrexia.
1. The anaesthetic complication malignant hyperpyrexia (MH) occurs in individuals and swine with a muscle membrane abnormality. 2. In an attempt to characterize this abnormality, the lipid and protein composition of muscle membranes from MH-susceptible swine was examined and compared with controls. 3. No significant abnormality in the membrane protein or lipid content of MH-susceptible muscle was detected.
D000818:Animals; D008305:Malignant Hyperthermia / Q000503:physiopathology*; D008563:Membrane Lipids / Q000032:analysis; D008565:Membrane Proteins / Q000032:analysis; D008861:Microsomes / Q000032:analysis; D009132:Muscles / Q000032:analysis*; D013552:Swine
D008563:Membrane Lipids; D008565:Membrane Proteins