[Lymphocyte serotonin receptors: a radioreceptor study].
The radioreceptor method was used to find high affinity, saturable and partially reversible specific binding of 3H-5HT with a gross membrane fraction of human peripheral blood lymphocytes. The Sketchard analysis demonstrated the presence of two types of the binding sites with equilibrium dissociation constants 2 nM and 66 nM. These characteristics are similar to those of 3H-5HT binding with the brain receptors. The results obtained suggest the existence on human lymphocytes of two types of serotonin receptors.
D001665:Binding Sites; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D011869:Radioligand Assay; D011985:Receptors, Serotonin / Q000032:analysis* / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism*; D014316:Tritium
D011985:Receptors, Serotonin; D014316:Tritium; D012701:Serotonin
Serotoninovye retseptory limfotsitov: radioretseptornoe issledovanie.