Interconversion of valine and leucine by Clostridium sporogenes.
Clostridium sporogenes has been found to require L-leucine and L-valine for growth in a minimal medium, although valine can be replaced by isobutyrate and leucine by isovalerate. Cells grown in minimal media incorporated significant 14C from [14C]valine into leucine and from [14C]leucine into valine. Growth with [4,5-3H]leucine also resulted in the incorporation of 3H into valine. These results indicate that these bacteria can interconvert leucine and valine.
D000596:Amino Acids / Q000378:metabolism; D002250:Carbon Radioisotopes; D003013:Clostridium / Q000254:growth & development / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism*; D014633:Valine / Q000378:metabolism*
D000596:Amino Acids; D002250:Carbon Radioisotopes; D007930:Leucine; D014633:Valine