Spinal decompression sickness: mechanical studies and a model.
Six experimental investigations of various mechanical aspects of the spinal cord are described relevant to its injury by gas deposited from solution by decompression. These show appreciable resistances to gas pockets dissipating by tracking along tissue boundaries or distending tissue, the back pressure often exceeding the probable blood perfusion pressure--particularly in the watershed zones. This leads to a simple mechanical model of spinal decompression sickness based on the vascular "waterfall" that is consistent with the pathology, the major quantitative aspects, and the symptomatology--especially the reversibility with recompression that is so difficult to explain by an embolic mechanism. The hypothesis is that autochthonous gas separating from solution in the spinal cord can reach sufficient local pressure to exceed the perfusion pressure and thus occlude blood flow.
D000818:Animals; D001696:Biomechanical Phenomena; D003665:Decompression Sickness / Q000209:etiology* / Q000503:physiopathology; D004242:Diving / Q000009:adverse effects*; D004285:Dogs; D005740:Gases / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D012039:Regional Blood Flow; D013118:Spinal Cord Diseases / Q000209:etiology* / Q000503:physiopathology
D005740:Gases