[Creatine kinase isoenzymes in severe head injury (author's transl)].
We measured the c.s.f. and serum creatine kinase activities in the first hours following the trauma, for 24 severe head injury patients. We found a good correlation between total CK and CKBB isoenzymes levels in the c.s.f. only. The c.s.f. values are a quantitative index of brain dysfunction assessed by the Liège coma scale, associating the Glasgow coma scale and the study of the brain stem reflexes. There is no relationship between CK activity and intracranial pressure.
D000293:Adolescent; D000328:Adult; D002648:Child; D003128:Coma / Q000201:enzymology* / Q000209:etiology; D006259:Craniocerebral Trauma / Q000150:complications / Q000201:enzymology*; D003402:Creatine Kinase / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged
D007527:Isoenzymes; D003402:Creatine Kinase
Etude isoenzymatique de la créatine kinase chez les traumatisés crâniens en coma.