Diuretic action of BTS 39542 (dihydrophthalazin-1-ylacetic acid) is consistent with inhibition of Na + K + Cl cotransport.
D001693:Biological Transport, Active / Q000187:drug effects; D002712:Chlorides / Q000378:metabolism*; D004232:Diuretics / Q000494:pharmacology*; D004848:Epithelium / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D005665:Furosemide / Q000494:pharmacology; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D010042:Ouabain / Q000494:pharmacology; D010793:Phthalazines / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism*; D011724:Pyridazines / Q000494:pharmacology*; D012964:Sodium / Q000378:metabolism*
D002712:Chlorides; D004232:Diuretics; D010793:Phthalazines; D011724:Pyridazines; C033364:BTS 39542; D010042:Ouabain; D005665:Furosemide; D012964:Sodium; D011188:Potassium