Intraoperative use of nifedipine for hemodynamic collapse due to coronary artery spasm following myocardial revascularization.
Sudden hemodynamic collapse in the perioperative period following myocardial revascularization may be due to coronary artery spasm. Nitroglycerin has been the standard treatment for this; however, it is not always effective, and the resultant morbidity and mortality are high. We present the case of a patient in whom sudden hemodynamic collapse due to coronary artery spasm was refractory to intravenously administered nitroglycerin but was relieved quickly with sublingually administered nifedipine. In certain selected patients in whom coronary artery spasm is responsible for myocardial collapse, the drug nifedipine may be effective in relieving this spasm and allowing for myocardial recovery.
D003329:Coronary Vasospasm / Q000150:complications / Q000188:drug therapy*; D006323:Heart Arrest / Q000188:drug therapy / Q000209:etiology; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000188:drug therapy / Q000209:etiology; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization; D009543:Nifedipine / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*
D011725:Pyridines; D009543:Nifedipine