Binding of heme by glutathione S-transferase: a possible role of the erythrocyte enzyme.
Human erythrocyte glutathione S-transferase activity is inhibited, probably competitively, by hemin with a Ki of 10(-7) M. It is postulated that glutathione S-transferase functions physiologically as a hemin-binding and/or transport protein in developing erythroid cells.
D002352:Carrier Proteins / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology*; D005982:Glutathione Transferase / Q000097:blood*; D006418:Heme / Q000378:metabolism*; D006801:Humans; D008722:Methods; D011485:Protein Binding
D002352:Carrier Proteins; D006418:Heme; D005982:Glutathione Transferase