Antibody response of swine experimentally infected with Mycoplasma hyosynoviae.
Antibody responses of swine inoculated intranasally with M. hyosynoviae were determined using complement-fixation, latex-agglutination, metabolic-inhibition, and mycoplasmacidal tests. The infected swine developed latex-agglutinating antibodies by 6 days postinoculation, complement-fixing and metabolic-inhibiting antibodies by 9-12 days, and mycoplasmacidal antibodies which were first detected from 12 days to 8 weeks postinoculation. Antibody titers persisted for as long as 6 months postinoculation. Complement-fixing and mycoplasmacidal antibodies were mainly IgG, and latex-agglutinating antibodies were IgM. Early metabolic-inhibiting antibodies were IgM while later antibodies were mainly IgG. None of the pigs had detectable complement-fixing antibodies to Mycoplasma hyorhinis.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D001170:Arthritis, Infectious / Q000276:immunology / Q000662:veterinary; D002850:Chromatography, Gel; D003168:Complement Fixation Tests / Q000662:veterinary; D007841:Latex Fixation Tests; D009174:Mycoplasma / Q000276:immunology; D009175:Mycoplasma Infections / Q000276:immunology / Q000662:veterinary*; D013552:Swine / Q000276:immunology; D013553:Swine Diseases / Q000276:immunology*
D000907:Antibodies, Bacterial