New taxanes from Taxus brevifolia.
The isolation of two taxanes from Taxus brevifolia Nutt. is described, together with the isolation of two acetylated taxol derivatives from an acetylated fraction from the same plant. The compounds were identified on the basis of their spectroscopic properties as taxa-4(20),11-diene-2 alpha, 5 alpha, 7 beta, 9 alpha, 10 beta, 13 alpha-hexaol 2,7,9,10,13-pentaacetate (1) (decinnamoyltaxinine J), 10-deacetylbaccatin III (2), taxol 2',7-diacetate (3), and 10-deacetyltaxol 2',7-diacetate (4).
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D001253:Astrocytes / Q000187:drug effects; D002460:Cell Line; D055598:Chemical Phenomena; D002621:Chemistry; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009303:Nasopharyngeal Neoplasms; D009374:Neoplasms, Experimental / Q000188:drug therapy
D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes