The protein tolerance of very low birth weight infants fed human milk protein enriched mother's milk.
Pooled breast milk was ultra-filtrated and freeze-dried to give a product with a protein content of 60 g/100 g powder. More than half of the secretory IgA activity against E. coli O antigen was preserved. This concentrated protein was added to the mother's fresh milk providing a protein supply of 3.0-3.5 g/kg/24 hours in four VLBW infants, at a calorie supply of 110 kcal/kg/24 hours. Growth followed the intrauterine rate. Free amino acid levels, acid-base balance and urea concentrations of peripheral whole blood indicated tolerance of the increased supply of human milk protein.
D000596:Amino Acids / Q000097:blood; D001806:Blood Urea Nitrogen; D005527:Food, Fortified; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008894:Milk Proteins / Q000008:administration & dosage*; D008895:Milk, Human; D011188:Potassium / Q000032:analysis; D012964:Sodium / Q000032:analysis
D000596:Amino Acids; D008894:Milk Proteins; D012964:Sodium; D011188:Potassium