Interactions between tryptophan and multilamellar liposomes. Effect of n-butanol on tryptophan fluorescence.
The fluorescence of indole ring of tryptophan is sensitive to the characteristics of the solvent in which it is located. So that is can be used as a probe of its microenvironment. In the present report we have studied fluorescence changes of tryptophan molecule located in multilamellar liposome of dipalmitoyl-lecithin (DPL). The temperature dependence of tryptophan fluorescence intensity shows increase related to the phase changes in DPL-liposomes. n-Butanol, a fluidizing agent, induces a linear dependence of tryptophan fluorescence from temperature.
D020001:1-Butanol; D000440:Butanols / Q000494:pharmacology*; D008081:Liposomes / Q000378:metabolism*; D010713:Phosphatidylcholines; D013050:Spectrometry, Fluorescence; D013696:Temperature; D014364:Tryptophan / Q000378:metabolism*
D000440:Butanols; D008081:Liposomes; D010713:Phosphatidylcholines; D014364:Tryptophan; D020001:1-Butanol