Cellular origin of prealbumin in the rat.
The synthetic rate of prealbumin and albumin in primary monolayer cultures of rat hepatocytes was measured by immunochemical methods. The isolated hepatocytes synthesized these proteins in the same ratio as that previously found for the whole body synthesis in vivo. It is concluded that the hepatocytes synthesize the main part of prealbumin in the rat.
D000818:Animals; D002478:Cells, Cultured; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D011228:Prealbumin / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D012709:Serum Albumin / Q000096:biosynthesis*
D011228:Prealbumin; D012709:Serum Albumin