[Dose-effect relationship of glucagon on the stomach, pylorus and duodenum].
The effect of glucagon on the stomach, pylorus and duodenum was evaluated within the first 30 minutes p.i. Glucagon was administered intravenously in a dose of 0.1, 0.2, 0.4, 0.6 and 1 mg. The hypotonic effect was greater on the duodenum than on the stomach. The dose response of the pylorus was not uniform. It was possible to point out a direct relationship between the intensity and duration of the hypotonic effect and the administered dosage.
D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D004386:Duodenum / Q000187:drug effects*; D005769:Gastrointestinal Motility / Q000187:drug effects*; D005934:Glucagon / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D011708:Pylorus / Q000187:drug effects; D013270:Stomach / Q000187:drug effects*
D005934:Glucagon
Dosis-Wirkungsbeziehung von Glukagon an Magen, Pylorus und Duodenum.