[Phagocyte characteristics in acute suppurative surgical infection].
The chemotaxis of PMN against E. coli filtrate, as well as the adherence and phagocytosis of bovine RBC, both uncoated and IgM-, IgG- or C'-coated, were studied in 10 healthy donors, 15 patients with local infections, 22 patients with the onset of the generalized infection and 25 patients with sepsis (including 7 patients with the lethal process). In patients with local infections the above-mentioned factors remained unchanged during treatment. In patients wit the onset of generalization chemotaxis and immune phagocytosis increased after the beginning of treatment. In septic patients showing a good response to treatment immune adherence and nonimmune, phagocytosis were stimulated. In patients with lethal sepsis a high level of immune adherence, but at the same time suppressed immune phagocytosis were observed.
D000208:Acute Disease; D002634:Chemotaxis, Leukocyte; D003165:Complement System Proteins / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D010586:Phagocytes / Q000276:immunology*; D010587:Phagocytosis; D011951:Receptors, Complement / Q000276:immunology; D011971:Receptors, Immunologic / Q000276:immunology; D013530:Surgical Wound Infection / Q000276:immunology*
D007136:Immunoglobulins; D011951:Receptors, Complement; D011971:Receptors, Immunologic; D003165:Complement System Proteins
Kharakteristika fagotsitov pri ostroĭ gnoĭnoĭ khirurgicheskoĭ infektsii.