Further studies with an inactivated oil emulsion Newcastle disease vaccine in broiler breeders.
Chickens vaccinated with a live Newcastle disease (ND) vaccine and subsequently revaccinated with an inactivated oil emulsion ND vaccine had higher and more persistent hemagglutination-inhibition (HI) antibody titers than birds vaccinated with live ND vaccine. The geometric mean HI antibody titers of flocks vaccinated with the inactivated ND vaccine ranged from 121 to 172, whereas the titers of flocks vaccinated every 90 days with a live ND vaccine ranged from 18 to 54. Breeder flocks revaccinated with live LaSota ND vaccine had lower egg production than the flocks vaccinated with inactivated vaccine. The average egg production per hen for the 40-week laying cycle was 174 and 170 eggs per hen for hens in the two houses vaccinated with the inactivated vaccine. Hens vaccinated with the live virus vaccine averaged 167 and 164 eggs per hen. The increase in egg production would more than offset the additional cost of the oil emulsion ND vaccine as well as the cost of injecting each individual bird at 18 weeks of age. Between 8 and 32 weeks after onset of egg production, geometric mean maternal antibody titers in 1-day-old chickens derived from breeders vaccinated with live ND vaccine ranged from 7 to 24, whereas, chicks from breeders vaccinated with the inactivated oil emulsion vaccine had maternal antibody titers that ranged from 64 to 89.
D000818:Animals; D002645:Chickens / Q000276:immunology*; D004655:Emulsions / Q000008:administration & dosage; D006389:Hemagglutinins, Viral / Q000032:analysis; D009521:Newcastle Disease / Q000276:immunology*; D009821:Oils / Q000008:administration & dosage; D011200:Poultry; D011201:Poultry Diseases / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000008:administration & dosage; D014765:Viral Vaccines / Q000008:administration & dosage*
D004655:Emulsions; D006389:Hemagglutinins, Viral; D009821:Oils; D014613:Vaccines, Attenuated; D014765:Viral Vaccines