[Profound granulocytopenia in a patient treated with propafenon ].
A case report concerning a 75 year old female patient whose treatment of multifocal ventricular extrasystoles and a ventricular tachycardia after an acute myocardial infarction consisted of multiple drugs, one of them being the antiarrhythmic substance Propafenon, is given. The patient developed a profound, but reversible, granulocytopenia, which disappeared nine days after discontinuing of most of the drugs. With the exemption of Propafenon all of the drugs were reinstituted after the remission: The not anymore needed ones only for a few days, all others until now, without ill effect. The patient is doing fairly well one year after this episode.
D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D011405:Propafenone; D011427:Propiophenones / Q000009:adverse effects*
D000889:Anti-Arrhythmia Agents; D011427:Propiophenones; D011405:Propafenone
Fallbericht einer schweren, möglicherweise propafenonverursachten Granulozytopenie.