[Intensified capacity of the lymphocytes of mice with repeated liver resection to transfer "regenerative information"].
It has been found that after extirpation of one liver lobe the lymphocytes of CBA mice did not stimulate the mitotic activity in the liver cells of non-operated syngeneic recipients. On the other hand, following single extirpation of 2/3 of the liver and after two-stage (with a 20-day break) removal of 2 liver lobes, mouse lymphocytes significantly stimulated the proliferative activity in the recipients' hepatocytes and Kupffer cells. The stimulation was organ-specific, since there was no variation in the mitotic index of renal cells in the experimental groups compared with controls. These data agree with the concept of the immune character of the capacity of lymphocytes to transfer "regenerative information".
D000818:Animals; D006498:Hepatectomy; D008115:Liver Regeneration; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008938:Mitosis; D012086:Reoperation
Usilenie sposobonosti limfotsitov mysheĭ s povtornoĭ rezektsieĭ pecheni k perenosu "regeneratsionnoĭ informatsii".