[Magnetic proton relaxation of aqueous solutions of ribonuclease in the temperature region of intramolecular melting].
Thermal denaturation of ribonuclease at NMR frequencies 22, 75, and 90 MHz was studied by proton magnetic relaxation. It has been found that the pattern of proton relaxation in denaturated macromolecule is determined by slow exchange tau M approximately 10(-2)--10(-3) sec of "rigidly bound" water molecules and the solvent as a whole.
D000818:Animals; D002417:Cattle; D004722:Endoribonucleases; D009682:Magnetic Resonance Spectroscopy; D008433:Mathematics; D010179:Pancreas / Q000201:enzymology; D011489:Protein Denaturation; D012259:Ribonuclease, Pancreatic; D013696:Temperature
D004722:Endoribonucleases; D012259:Ribonuclease, Pancreatic
Magnitnaia protonnaia relaksatsiia vodnykh rastvorov ribonukleazy v oblasti temperatur vnutrimolekuliarnogo plavleniia.