An update on the holoprosencephalic disorders.
Holoprosencephaly is an etiologically heterogeneous condition. Recently a number of new causes have come to light, several syndromes have been delineated or partially delineated, and a few associations have become apparent. This article updates the nosology of human holoprosencephaly.
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000235:genetics; D001921:Brain / Q000002:abnormalities*; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005145:Face / Q000002:abnormalities*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications; D007180:Incisor / Q000002:abnormalities; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000150:complications