Effect of infarct location on the in-hospital prognosis of patients with first transmural myocardial infarction.
We studied the in-hospital prognosis of 1105 patients who had their first transmural myocardial infarction; 611 patients (55.3%) had anterior myocardial infarction (AMI) and 494 (44.7%) had inferior myocardial infarction (IMI). Patients with IMI had a significantly lower in-hospital mortality rate (9.1% vs 15.6%, p = 0.0014) and significantly lower prevalences of congestive heart failure (39.4% vs 47.6%, p = 0.0066), cardiogenic shock ( 8.7% vs 12.6%, p = 0.0384) and conduction defects (left anterior hemiblock, right bundle branch block and intraventricular conduction defect). The patients with AMI had significantly higher peak enzyme levels, and a greater percentage of them (40.1% vs 25.9%) had SGOT greater than 240 IU/l, whereas more patients with IMI (34.6% vs 27.8%) had SGOT less than 120 IU/l (p = 0.0001). When the parallel subgroups were compared according to the peak SGOT levels (less than 120, 120-240, and greater than 240 IU/l, the differences in the mortality and morbidity between the two infarct locations diminished. However, patients with AMI still had a less favorable outcome. Logistic regression analysis demonstrated that both the peak enzyme level and the infarct location had an independent influence on the in-hospital prognosis of patients with first transmural infarction.
D000368:Aged; D001219:Aspartate Aminotransferases / Q000097:blood; D048909:Diabetes Complications; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000401:mortality*; D011379:Prognosis; D012770:Shock, Cardiogenic / Q000150:complications
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases