A long-term follow-up study of the arterial pressure dynamics after nephrectomy in patients with renal hypertension.
For periods of 3 to 15 years after unilateral nephrectomy the arterial pressure dynamics was studied in 131 patients. In 18 patients with and 12 patients without remission of hypertension the renal haemodynamics was studied before and after nephrectomy. The functional compensatory mechanisms of the remaining kidney are assessed on the basis of preoperative checkings of selective renal haemodynamics and of the activities of the renin-angiotensin and prostaglandin systems in 10 patients with absent and 15 patients with decreased excretory function of one kidney. In the authors' opinion, the blood flow in the contralateral kidney increases, at lacking excretory function of the other kidney, owing to enhanced prostaglandin A2 synthesis in the contralateral kidney.
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006977:Hypertension, Renal / Q000503:physiopathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy