Ticarcillin-induced immune haemolytic anaemia.
Immune haemolytic anaemia may be induced by high doses of benzylpenicillin. A small number of cases have also followed the administration of semisynthetic penicillins in addition to benzylpenicillin. We have observed immune haemolytic anemia consequent on ticarcillin administration in a patient who had previously received benzylpenicillin. Although the antibody agglutinated penicillin-treated and ticarcillin-treated cells it was demonstrated by serum fractionation to be IgG.
D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000139:chemically induced* / Q000276:immunology; D003429:Cross Reactions; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D008297:Male; D010400:Penicillin G / Q000009:adverse effects; D010406:Penicillins / Q000009:adverse effects*; D013982:Ticarcillin / Q000009:adverse effects* / Q000627:therapeutic use
D007074:Immunoglobulin G; D010406:Penicillins; D013982:Ticarcillin; D010400:Penicillin G