Chromosome 8-14 translocation in a non-African Burkitt's lymphoma with leukemic conversion.
A specific chromosome translocation, t(8q-; 14q+), was observed in a 43-year-old female with non-African Burkitt's lymphoma in which leukemic conversion had occurred. The chromosome studies used cells from ascites. The ascites was apparently the result of a primary tumor involving the ovaries and contained 68% of lymphoma cells. The frequent occurrence of abnormalities related to chromosomes 1, 8 and 14 in African and non-African Burkitt's lymphomas was emphasized.
D000328:Adult; D002051:Burkitt Lymphoma / Q000235:genetics*; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007938:Leukemia / Q000209:etiology*; D014178:Translocation, Genetic