Serotoninergic agents in the treatment of isolated sleep paralysis.
The authors report three cases of isolated sleep paralysis controlled by L-tryptophan with or without amitriptyline. Both agents increase CNS 5-hydroxytryptamine availability, whereas imipramine, which was ineffective in the one case in which it was tried, affects predominantly norepinephrine reuptake.
D000328:Adult; D000639:Amitriptyline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010243:Paralysis / Q000188:drug therapy*; D012890:Sleep / Q000187:drug effects; D012893:Sleep Wake Disorders / Q000188:drug therapy*; D014364:Tryptophan / Q000627:therapeutic use*
D000639:Amitriptyline; D014364:Tryptophan