A case-control study of cancer of the endometrium.
A hospital-based case-control study of the epidemiology of endometrial cancer in women aged 45-74 years was carried out in Connecticut from 1977 to 1979. In total, 167 cases and 903 controls were included. Elevated risks were associated with the following factors: overweight, nulliparity, few pregnancies, use of estrogen replacement therapy, older age at menopause, and a history of ovarian or endometrial cancer in mother or a sister. Whites were more frequently affected than blacks, and better-educated women more often than less-educated women. Use of oral contraceptives was associated with a decreased risk, although the decrease did not reach statistical significance.
D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D001835:Body Weight; D003237:Connecticut; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D010298:Parity; D012306:Risk; D011795:Surveys and Questionnaires; D013997:Time Factors; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000209:etiology*
D003276:Contraceptives, Oral