H4-isozyme of lactate dehydrogenase in the solution of sodium chloride--II. The effect of ADP-ribose on the molecular weight.
1. Large tetramer fractions were formed when ADP-ribose was added to H4-isozyme of lactate dehydrogenase. 2. In the presence of ADP-ribose, not only the increase in tetramers was observed but also the existence of octamers and aggregates. 3. The dimer fraction decreased markedly. 4. Two pathways in the formation of aggregates were suggested; one starting from monomers and the other from octamers.
D000246:Adenosine Diphosphate Ribose; D055598:Chemical Phenomena; D002621:Chemistry; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D008970:Molecular Weight; D009702:Nucleoside Diphosphate Sugars; D012965:Sodium Chloride; D012996:Solutions
D007527:Isoenzymes; D009702:Nucleoside Diphosphate Sugars; D012996:Solutions; D000246:Adenosine Diphosphate Ribose; D012965:Sodium Chloride; D007770:L-Lactate Dehydrogenase