[Cellular immunity factors in the pathogenesis of recurrences of chronic herpetic infection].
Comparative studies of various factors of cellular immunity in human chronic herpetic stomatitis (CHS) in periods of relapses and remission of the infection revealed no significant changes in specific cellular immune response, blasttransformation of lymphocytes to herpes simplex virus antigen. At the same time, the indices of nonspecific cellular responsiveness: the rosette-forming activity of T-lymphocytes and the level of leukocyte interferon were markedly reduced in the period of recurrence of the infection and increased as remission developed. The role of immune factors in the pathogenesis of herpes relapses is discussed.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D007111:Immunity, Cellular; D007113:Immunity, Innate; D007370:Interferon Type I / Q000276:immunology; D008213:Lymphocyte Activation; D008875:Middle Aged; D012008:Recurrence; D012397:Rosette Formation; D013283:Stomatitis, Herpetic / Q000209:etiology / Q000276:immunology*
D007370:Interferon Type I
Faktory kletochnogo immuniteta v patogeneze retsidivov khronicheskoĭ gerpeticheskoĭ infektsii.