Reversal by bethanechol of sexual dysfunction caused by anticholinergic antidepressants.
The anticholinergic properties of currently available antidepressants sometimes cause sexual dysfunction. Bethanechol, a cholinergic drug, was found to give total relief of impotence in two men and of anorgasmy in one woman; none of the subjects suffered side effects.
D000328:Adult; D000657:Amoxapine / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects*; D001626:Bethanechol Compounds / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007520:Isocarboxazid / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced* / Q000188:drug therapy; D014191:Tranylcypromine / Q000009:adverse effects
D000928:Antidepressive Agents; D001626:Bethanechol Compounds; D007520:Isocarboxazid; D014191:Tranylcypromine; D000657:Amoxapine