Solvent abuse associated cortical atrophy.
Eleven of 42 toluene inhalers were evaluated with computed tomography scans because of neurologic abnormalities. Six of the 11 were found to have cerebral cortical atrophy. In addition, two of the six had cerebellar atrophy. All six had been exposed to toluene for at least 10 years. This study suggests that atrophy of the central nervous system may occur in chronic toluene abusers.
D000293:Adolescent; D000328:Adult; D001284:Atrophy; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002493:Central Nervous System Diseases / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male; D019966:Substance-Related Disorders / Q000150:complications*; D014050:Toluene; D014057:Tomography, X-Ray Computed
D014050:Toluene