Confusional paranoid psychosis after withdrawal from sympathomimetic amines: two case reports.
Paranoid psychosis may result from intoxication with, or withdrawal from amphetamines. The authors describe two cases of paranoid confusional psychosis commencing 1 week after the patients' withdrawal from sympathomimetic amines. The pathophysiology for this unusual disorder may be agonist-induced dopamine receptor hypersensitivity.
D000328:Adult; D000368:Aged; D003863:Depression / Q000188:drug therapy; D003913:Dextroamphetamine / Q000009:adverse effects*; D004053:Diethylpropion / Q000009:adverse effects*; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009765:Obesity / Q000188:drug therapy; D010259:Paranoid Disorders / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D011954:Receptors, Dopamine / Q000502:physiology; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
D011954:Receptors, Dopamine; D006220:Haloperidol; D004053:Diethylpropion; D003913:Dextroamphetamine