An infant with chronic, relapsing polyneuropathy responsive to steroids.
A seven-week-old infant presented with an acute flaccid paraparesis. Her subsequent course was punctuated by numerous exacerbations, in association with minor intercurrent illness and remissions produced by corticosteroid treatment. Postmortem examination revealed a chronic inflammatory polyradiculopathy. She represents the youngest patient yet described with a chronic, relapsing, steroid-responsive polyneuropathy.
D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D005799:Genes, Dominant; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009133:Muscular Atrophy / Q000235:genetics; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure; D009431:Neural Conduction / Q000187:drug effects; D010264:Paraplegia / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D010375:Pedigree; D010543:Peroneal Nerve / Q000187:drug effects; D011115:Polyneuropathies / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use*; D013497:Sural Nerve / Q000473:pathology
D011241:Prednisone