[Body lipid removal by means of continuous plasma extraction].
A method of continuous extraction of hydrophobic compounds from blood plasma is described. It is based on the passing of plasma through a column containing styrenedivinylbenzene copolymer-swollen in chloroform. Lipids are extracted from donor's plasma and in vivo from animal blood (dogs). The animal operations consisted of the following stages: taking arterial blood, separation of plasma and blood cells, extraction of lipids from plasma, mixing of plasma and cells after treatment and returning of the processed blood into the body. It was found that extraction does not influence the plasma protein content but reduces the lipid content, particularly that of triglycerides. It is suggested that lipids weakly connected with proteins are mainly extracted. The follow-up for a week has shown that the animals satisfactorily tolerated the operations.
D000818:Animals; D004285:Dogs; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood / Q000302:isolation & purification*; D008297:Male; D010956:Plasmapheresis / Q000295:instrumentation / Q000379:methods*
D008055:Lipids
Delipidizatsiia organizma metodom nepreryvnoĭ plazmoékstraktsii.