Effective radiotherapy in one case of dermatofibrosarcoma protuberans.
A case of dermatofibrosarcoma protuberans is presented where radiotherapy had been part of the management of multiple recurrent lesions. Over a course of 46 years, complete response occurred in 2 out of 3 lesions after medium-and high-dose radiation therapy and in 1 out of 5 lesions after interstitial therapy. Regression of the lesions took several months. In the literature, 5 additional cases of local control and 2 of partial control after high-dose radiotherapy are reported. When failure of radiotherapy was reported, the dose had been low and the observation time short in many cases. High-dose radiotherapy used with patience might be tried in selected cases.
D000328:Adult; D005260:Female; D005354:Fibrosarcoma / Q000532:radiotherapy*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000532:radiotherapy*; D013997:Time Factors