title: Effectiveness of Cf 252-neutrons at low dose rates.
abstract: Californium-252, an isotope emitting neutrons, gamma photons and alpha particles, is being investigated for its practical use in interstitial Curie therapy. After an introduction in which the history of Californium-252 and its application in industry are described, a review of results concerning RBE values of Cf-neutrons for tolerance of different types of normal tissues and for responses of experimental tumors as a function of dose rate is given. In addition, a review of clinical results is presented.
mesh_terms: D000818:Animals; D001918:Brachytherapy; D002142:Californium / Q000627:therapeutic use*; D005214:Fast Neutrons; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D009502:Neutrons; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness
chemical_list: D002142:Californium