[Creatine kinase BB with atypical migration. Possible role of IgA in its formation].
We studied the behaviour of an atypical CK in one female patient. Using exclusion-diffusion chromatography of the serum, on Sephadex G 200, we observed the simultaneous elution of a CK-BB and IgA. We demonstrated that this eluate contained the components responsible for this atypical CK. The study of the behaviour of this enzyme complex reveals a resemblance with that of immune complexes.
D000368:Aged; D000936:Antigen-Antibody Complex / Q000302:isolation & purification; D002850:Chromatography, Gel; D003402:Creatine Kinase / Q000097:blood* / Q000276:immunology; D004586:Electrophoresis; D004696:Endocarditis / Q000150:complications; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000302:isolation & purification*; D007527:Isoenzymes; D008944:Mitral Valve Insufficiency / Q000097:blood / Q000209:etiology / Q000276:immunology*
D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A; D007527:Isoenzymes; D003402:Creatine Kinase
Etude d'une créatine-kinase BB de migration atypique. Rôle éventuel des IgA dans sa formation.