On the interaction between anthralin and DNA: a revision.
The interaction between anthralin and DNA in vitro was examined. According to our data, there is no evidence for a specific interaction between these substances. However, we found that the addition of small quantities of DNA or albumin significantly enhanced the stability of aqueous solutions of anthralin and markedly affected the rate of anthralin decomposition.
D000818:Animals; D000873:Anthracenes / Q000494:pharmacology*; D000875:Anthralin / Q000008:administration & dosage / Q000494:pharmacology*; D002417:Cattle; D003470:Culture Media; D004247:DNA / Q000008:administration & dosage / Q000494:pharmacology*; D004347:Drug Interactions; D004355:Drug Stability; D005399:Fishes; D066298:In Vitro Techniques; D008297:Male; D012710:Serum Albumin, Bovine / Q000008:administration & dosage / Q000494:pharmacology; D012996:Solutions; D013094:Spermatozoa
D000873:Anthracenes; D003470:Culture Media; D012996:Solutions; D012710:Serum Albumin, Bovine; D004247:DNA; D000875:Anthralin