Sodium and chloride transport across the isolated rabbit ciliary body.
Unidirectional Na+ and Cl- fluxes were determined in the isolated rabbit ciliary body under short-circuited conditions. A statistically significant net Cl- flux towards aqueous was detected in the standard bathing solution (HCO3- = 115 mM), but no net Na+ flux was demonstrated in this solution. The net Cl- flux exceeded the short-circuit current, suggesting the existence of a net flux of other ion(s). In a bathing solution containing 5 mM HCO3-, the net Cl- flux was abolished, suggesting that HCO3- in the bathing solution enhances the net Cl- flux.
D000200:Action Potentials; D000818:Animals; D001082:Aqueous Humor / Q000502:physiology; D001692:Biological Transport; D002713:Chlorine; D002924:Ciliary Body / Q000502:physiology*; D005260:Female; D066298:In Vitro Techniques; D007477:Ions; D008297:Male; D011817:Rabbits; D012964:Sodium / Q000502:physiology*
D007477:Ions; D002713:Chlorine; D012964:Sodium