Polycystic ovarian syndrome; a retrospective study of the therapeutic effect of ovarian wedge resection after unsuccessful treatment with clomiphene citrate.
The therapeutic effect of ovarian wedge resection (OWR) was evaluated in a study of 92 patients with polycystic ovarian syndrome who did not conceive after clomiphene treatment. The frequency of ovulation was significantly higher after OWR than before (0.02 less than P less than 0.05). Postoperatively, 58 of the patients (63%) attained pregnancy one or more times, either spontaneously or after induction of ovulation. The beneficial effect of OWR on menstrual irregularities was significant (P less than 0.001).
D000328:Adult; D002996:Clomiphene / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000209:etiology; D008722:Methods; D010053:Ovary / Q000601:surgery*; D010060:Ovulation; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D012189:Retrospective Studies
D002996:Clomiphene