title: Vitamin C in normal human mononuclear and polymorphonuclear leukocytes.
abstract: Human peripheral leukocytes from healthy donors have been isolated by means of a suitable separation method to obtain a high yield of lymphocytes and granulocytes with a very low contamination of platelets and red blood cells. Mononuclear cells so purified contain more than double amounts of vitamin C than polymorphonuclear cells. The difference between lymphocytes and granulocytes content also tends to be larger at increasing vitamin concentrations in total leukocytes. A higher level of vitamin C is displayed by the mononuclear cells obtained from women in respect to men, while no significant difference is found in the polymorphonuclear cells.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001205:Ascorbic Acid / Q000097:blood*; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000378:metabolism*; D009504:Neutrophils / Q000378:metabolism*; D012737:Sex Factors
chemical_list: D001205:Ascorbic Acid