[Catecholamines in the myocardium of growing rats after pharmacological sympathectomy].
Examination of the myocardium of 7-, 30-day and 3--5-month-old rats has shown that the content of noradrenaline and adrenaline increased with age. The sympatholytics, reserpine and ornid diminished more markedly the content of catecholamines in the myocardium of 7- and 30-day-old animals. Dopegyt produced a greater catecholamine-reducing effect in 3--5-month-old animals. It is inferred that in the early postnatal ontogenesis, the myocardial response to the sympatholytics is determined by age-associated features of adrenergic control and metabolism.
D000375:Aging / Q000187:drug effects*; D000818:Animals; D004837:Epinephrine / Q000378:metabolism*; D005260:Female; D006321:Heart / Q000187:drug effects*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D013563:Sympathectomy, Chemical; D013565:Sympatholytics / Q000494:pharmacology*
D013565:Sympatholytics; D009638:Norepinephrine; D004837:Epinephrine
Katekholaminy v miokarde rastushchikh krys pri farmakologicheskoĭ desimpatizatsii.