title: [Characteristics of the infectious process in animals susceptible and resistant to glanders].
abstract: Combined bacteriological, pathomorphological, luminescent-serological, and electron microscopic studies were used to elucidate some aspects of pathogenesis of glanders in animals with different susceptibility to this infection. The animals highly susceptible to glanders (golden hamsters) were shown to develop the infection of the sepsis type with granulomas of the exudative nature. In the animals highly susceptible to glanders the bacteria were proved experimentally to parasitize in a rod-shaped form within macrophages of the spleen, liver, and lungs as well as extracellularly. In white mice resistant to glanders the infection developed as chronic septicemia with granulomas of the exudative-proliferative nature. Glanders bacteria in this animal species undergo L-transformation.
mesh_terms: D000818:Animals; D006224:Cricetinae; D004198:Disease Susceptibility; D005896:Glanders / Q000473:pathology*; D006168:Guinea Pigs; D006736:Horses; D008099:Liver / Q000473:pathology* / Q000648:ultrastructure; D008198:Lymph Nodes / Q000473:pathology*; D008647:Mesocricetus; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D013154:Spleen / Q000473:pathology* / Q000648:ultrastructure
vernacular_title: Osobennosti infektsionnogo protsessa u chuvstvitel'nykh i rezistentnykh k sapu zhivotnykh.