[Morphometric characteristics of the blood vessels of the pulmonary circulation in the lung following unilateral pneumonectomy].
In 29 mongrel dogs with the body mass of 20-27 kg a left-sided pulmonectomy was performed. The right lung was examined 1, 3, 7, 15 days and 1, 2, 4, 6 months after the operation. Postmortem injection of its circulatory bed with roentgen-opaque dyes was performed, then total cleared preparations and histotopograms were made. Morphometrical analysis of branches running off the pulmonary arteries of the muscular type was carried out in the reconstructed vessels. The animals' hearts were subjected to certain macro-morphometrical methods of investigation. A complex analysis of the macro-microscopic and morphometrical investigation of the pulmonary circulation vessels revealed a definite tendency in the dynamics of the vascular changes. In large branches of the pulmonary artery belonging to the muscular-elastic and elastic types, a predominant dilatatory reaction was noted in the whole course of the experiment, while for the branches of the muscular type morphological signs of spasm were specific during the first 3 days after the operation. Only after 7-60 days dilatation in the branches of the muscular type was observed with a subsequent normalization of their tonus. In tributaries of the pulmonary veins and capillaries, the dilatatory reactions were revealed to predominate. An increased loading on the right cardiac parts could be considered as a mechanism ensuring a maximal effective functioning of the pulmonary circulation after a unilateral pulmonectomy.
D000818:Animals; D001163:Arteriovenous Anastomosis / Q000033:anatomy & histology; D004285:Dogs; D006321:Heart / Q000033:anatomy & histology; D009929:Organ Size; D011013:Pneumonectomy; D011651:Pulmonary Artery / Q000033:anatomy & histology*; D011652:Pulmonary Circulation; D011667:Pulmonary Veins / Q000033:anatomy & histology*; D014664:Vasodilation
Morfometricheskaia kharakteristika sosudov malogo kruga krovoobrashcheniia v legkom posle odnostoronneĭ pul'monéktomii.