Analysis and formation of nitrosamines in the human intestine.
The method employed for nitrosamine analysis gave high recovery values and did not produce artefactual nitrosamines. Nitrosation reactions are not catalysed by the microbial ecosystem of human feces. Rapid loss of nitrate and nitrite in feces also precludes nitrosamine formation, unless very high concentrations of precursors are present. These concentrations are not physiological and it is therefore unlikely that N-nitroso compounds form in the lower gastrointestinal tract of man.
D005243:Feces / Q000032:analysis; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism*; D009602:Nitrosamines / Q000032:analysis* / Q000378:metabolism
D009602:Nitrosamines