title: Epidemiological study and comparison of pyrantel and levamisole in the treatment of roundworm and hookworm infestations.
abstract: Stool examined for presence of nematodes from 467 school students in Dacca city showed 48% ova positive cases with 22% among them cases of mixed nematode infection. Highest prevalence of 58% was observed with roundworm and 5% was hookworm infestations. Among hookworm cases, Necator americana (68%) appears to be the predominant species. Two anthelmintics-pyrantel and levamisole achieved similar high cure rate (around 97%) and Egg reduction rate of 99% in roundworm infection. However, pyrantel was observed to be more effective in hookworm infestation (87% against 60%) particularly in Necator americana cases.
mesh_terms: D000293:Adolescent; D000328:Adult; D001459:Bangladesh; D002648:Child; D006725:Hookworm Infections / Q000188:drug therapy*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D010270:Parasite Egg Count; D011715:Pyrantel / Q000627:therapeutic use*
chemical_list: D007978:Levamisole; D011715:Pyrantel