Screening for penicillin tolerance in viridans streptococci by a simple disk method.
A disk method was developed for demonstrating penicillin tolerance in viridans streptococci. This was achieved by the substitution of the penicillin disk used for susceptibility testing by a disk containing penicillinase. After reincubation, penicillin-tolerant strains exhibited new growth in the area adjacent to this disk, providing a rapid screening test.
D004361:Drug Tolerance; D008826:Microbial Sensitivity Tests / Q000379:methods*; D010406:Penicillins / Q000494:pharmacology*; D013291:Streptococcus / Q000187:drug effects*
D010406:Penicillins