Mapping of the neural activity in the cerebellum of the mouse during stepping by means of 2-deoxyglucose autoradiography.
Incorporation of radioactive 2-deoxy-D-glucose (2-DG) into the cerebellum of mice which were resting in a cage or stepping on a treadmill was examined by means of autoradiography. In the cerebellum of the mouse resting in the cage, a large amount of 2-DG was incorporated into the posterior vermis, the flocculus, cerebellar nuclei and vestibular nuclei. On the other hand, during stepping, incorporation of 2-DG was increased remarkably in the anterior vermis, the pyramis, the anterior part of the ansiform lobule and the paraflcculus, indicating that these regions are functionally involved in locomotor movements.
D000818:Animals; D001345:Autoradiography; D001786:Blood Glucose / Q000378:metabolism*; D001931:Brain Mapping; D001933:Brain Stem / Q000502:physiology; D002529:Cerebellar Nuclei / Q000502:physiology; D002531:Cerebellum / Q000502:physiology*; D003847:Deoxyglucose / Q000097:blood; D008124:Locomotion; D051379:Mice; D008809:Mice, Inbred C3H; D009043:Motor Activity / Q000502:physiology*; D009474:Neurons / Q000502:physiology
D001786:Blood Glucose; D003847:Deoxyglucose