Effects of sympathetic nerve stimulation on intra-oral mechanoreceptor activity in the cat.
1. Micro-electrode recordings were made from intra-oral mechanoreceptor neurones in the trigeminal ganglion and mesencephalic nucleus of the fifth nerve in the cat.2. The effect of cervical sympathetic trunk stimulation on the discharge of the mechanoreceptors to a controlled force was observed.3. Almost half of the mechanoreceptor neurones studied were modulated by sympathetic stimulation. Sympathetic stimulation both decreased the impulse frequency to a controlled force application and raised the threshold in these receptors. The remainder were unaffected by sympathetic stimulation.4. In previous studies involving recordings from either the trigeminal ganglion or mesencephalic nucleus no spontaneously active slowly adapting intra-oral mechanoreceptors have been observed, yet in peripheral alveolar nerve studies many workers have reported spontaneously discharging neurones. In the present study spontaneous activity has been recorded from intra-oral mechanoreceptors both in the trigeminal ganglion and in the mesencephalic nucleus after cutting the cervical sympathetic trunk. The spontaneous activity could be abolished in all cases but one, by sympathetic stimulation. It is suggested that reported spontaneous activity from intra-oral mechanoreceptors could be due to cutting the peripheral nerve and therefore the sympathetic supply, thus removing an inhibitory influence from the sensory unit. The means by which the sympathetic supply inhibits the sensory unit has not been resolved.
D000200:Action Potentials; D000818:Animals; D001931:Brain Mapping; D002415:Cats; D004558:Electric Stimulation; D008465:Mechanoreceptors / Q000502:physiology*; D008636:Mesencephalon / Q000502:physiology; D010519:Periodontium / Q000294:innervation*; D013564:Sympathetic Nervous System / Q000502:physiology; D014276:Trigeminal Nerve / Q000502:physiology