title: Nonmutagenicity in vivo of the food flavonol quercetin.
abstract: Mice given quercetin per os at concentrations that were about 10(3) times greater than the estimated average human intake of total flavonols were tested for mutagenicity with 2 complementary in vivo mutagenicity/carcinogenicity screening tests--the micronucleus test and the host-mediated assay employing the Ames Salmonella tester strain TA 98 as indicator organism. No mutagenic effect was detected with either test.
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000633:toxicity*; D005769:Gastrointestinal Motility / Q000187:drug effects; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens; D011794:Quercetin / Q000633:toxicity*
chemical_list: D005419:Flavonoids; D009153:Mutagens; D011794:Quercetin