[Comparative evaluation of the therapeutic effectiveness of drugs of different mechanisms of action in cerebral atherosclerosis].
The author describes the results of treatment of 299 patients with clinical evidence of cerebral atherosclerosis receiving three groups of antiatherosclerotic agents: improving cerebral blood flow (naftidrofuryl, cinnarazine, pyridinol carbamate, low-molecular dextran), normalizing lipid metabolism (clofibrate, heparinoid, alpha-tocopherol, Procetophen) and improving the metabolism of nerve cells (piracetam, pyritinol). After a statistical analysis of the results of the author evaluated the effectiveness of these drugs in various groups and suggested practical conclusions and treatment schedules in various forms of cerebral atherosclerosis.
D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001921:Brain / Q000166:cytology*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D002936:Cinnarizine / Q000627:therapeutic use; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D002537:Intracranial Arteriosclerosis / Q000188:drug therapy*; D050356:Lipid Metabolism; D009257:Nafronyl / Q000627:therapeutic use; D010889:Piracetam / Q000627:therapeutic use; D011746:Pyrithioxin / Q000627:therapeutic use
D000924:Anticholesteremic Agents; D000960:Hypolipidemic Agents; D002936:Cinnarizine; D009257:Nafronyl; D011746:Pyrithioxin; D010889:Piracetam
Porównawcza ocena skuteczności terapeutycznej leków z róznymi mechanizmami działania w miazdzycy mózgu.