[Reversible changes in the volume of isolated mitochondria in the course of ion flux oscillations between the mitochondria and the medium].
Glutaraldehyde has been used for electron microscopic studies of mitochondrial volume fluctuation during Sr2+--induced oscillation of ion fluxes. It has been shown that the observed ultrastructural and fluctuations of mitochondria is reversible to correlate with light-scattering value as well as to the direction of ion transfer. Determination of the intramitochondrial volume at different stages of oscillatory cycle shows the increase in the volume during the process of swelling up to 2.4-5.6 times compared with the shrihkate state.
D000818:Animals; D066298:In Vitro Techniques; D007474:Ion Exchange; D008027:Light; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects; D008930:Mitochondria, Liver / Q000187:drug effects / Q000502:physiology*; D008933:Mitochondrial Swelling / Q000187:drug effects; D011188:Potassium / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012542:Scattering, Radiation; D013324:Strontium / Q000378:metabolism / Q000494:pharmacology; D014634:Valinomycin / Q000494:pharmacology
D014634:Valinomycin; D011188:Potassium; D013324:Strontium
Obratimye izmeneniia ob"ema izolirovannykh mitokhondriĭ v khode kolebaniĭ ionnykh potokov mezhdu mitokhondriiami i sredoĭ.