title: Design, development and test results of a horizontal flow inhalation toxicology facility.
abstract: A horizontal flow chamber was developed for the purposes of conducting inhalation toxicology research. The chamber utilizes a unique diffuser system and pre-mixing of contaminants to achieve uniform exposure. The use of fecal catch pans eliminates exposure of animals to fecal debris from overhead animals. The chamber performance shows a rapid equilibrium in startup and shutdown.
mesh_terms: D000392:Air Movements; D000818:Animals; D001273:Atmosphere Exposure Chambers; D004058:Diffusion; D005243:Feces; D051381:Rats; D011916:Rats, Inbred F344; D014116:Toxicology / Q000295:instrumentation* / Q000379:methods