Synchronization of double asymmetrical epileptogenic foci in the cerebral cortex of the rat.
Discharges of two asymmetrical penicillin foci progressively synchronized during 25 min after creation of these foci. Section of the corpus callosum seriously impaired but did not completely block this synchronization. Thalamic spreading depression did not significantly change the synchronization in rats with intact corpus callosum. Noncallosal component of synchronization is probably realized through brain stem structures.
D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects*; D003337:Corpus Callosum / Q000187:drug effects; D003344:Cortical Synchronization; D004292:Dominance, Cerebral / Q000187:drug effects*; D004569:Electroencephalography; D008297:Male; D009434:Neural Pathways / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000139:chemically induced*; D013787:Thalamic Nuclei / Q000187:drug effects