title: [Diagnosis and therapy of hirsutism].
abstract: In ten of 12 patients with non-progressive hirsutism a pathologic pattern of androgens was assessed by hormone determinations. Using a new test procedure increased androgen production could be tentatively associated with an impaired function of either ovaries or adrenals. Androgen-producing tumors could be excluded. With differential therapy (progestins, estrogens, corticosteroids, antiandrogens) pathologic androgen serum levels subsided already prior to antiandrogen medication. Definite clinical success was, however, observed only it antiandrogen therapy. As long-term therapy a low-dose antiandrogen-estrogen combination proved valuable.
mesh_terms: D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000728:Androgens / Q000378:metabolism; D003276:Contraceptives, Oral / Q000627:therapeutic use; D003907:Dexamethasone; D005260:Female; D006628:Hirsutism / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans
chemical_list: D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D000305:Adrenal Cortex Hormones; D000728:Androgens; D003276:Contraceptives, Oral; D003907:Dexamethasone
vernacular_title: Diagnostik und Therapie des Hirsutismus.