Induction of prostate adenocarcinomas in Lobund Wistar rats by testosterone.
Prostate adenocarcinomas were induced in Lobund Wistar rats following subcutaneous implants of silastic chambers containing testosterone propionate. The tumors resembled those that developed spontaneously in the Lobund Wistar rats. Tumors were not induced in ACI rats by the same treatment schedule.
D000230:Adenocarcinoma / Q000139:chemically induced* / Q000473:pathology; D000818:Animals; D008297:Male; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology; D011471:Prostatic Neoplasms / Q000139:chemically induced* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D013739:Testosterone / Q000009:adverse effects*
D013739:Testosterone