title: [Ischemic bone necrosis in Itsenko-Cushing disease].
abstract: X-ray alterations of the type ischemic osseous necrosis were established in three patients (two females and one male) with Icenko-Cushing disease. In the first case--the haed of femur was unilaterally affected: in the second--bilateral lesions with the same localization; and in the third--a combination of changes in the head of femur and the heads of some metatarsal bones. In all patients, secondary ostheoarthrosis alterations were also observed. The tomographic study enabled the visualization of details, characterizing the stage of the progress of the process. The similarity in the roentgenological images, with a substrate of ischemic osseous necrosis in case of exogenous and endogenous hypercortisolism, provide grounds to admit a similarity in the pathogenesis of those states.
mesh_terms: D000328:Adult; D003480:Cushing Syndrome / Q000150:complications*; D005260:Female; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008684:Metatarsus; D008875:Middle Aged; D010020:Osteonecrosis / Q000209:etiology*; D011859:Radiography
chemical_list: D006854:Hydrocortisone
vernacular_title: Kum vuprosa za iskhemichnite kostni nekrozy pri bolestta na Itsenko--Cushing.