title: [Dynamics and factors regulating the humoral immune response to Staphylococcus].
abstract: After repeated immunization of CBA mice with corpuscular staphylococcal antigen the titer of serum antibodies to staphylococci was the same as after single immunization, irrespective of the duration of the interval between injections. The increase of the interval between injections contributed to an increase in the titer of antibodies resistant to 2-mercaptoethanol. Mouse serum obtained 6 days after immunization suppressed humoral immune response to staphylococci. When injected intravenously into syngeneic mice, splenocytes taken from immune mice 3, 6 and 10 days after their immunization with staphylococcal antigen enhanced humoral immune response to staphylococci.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000942:Antigens, Bacterial / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D007114:Immunization; D007117:Immunization, Secondary; D051379:Mice; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology; D013211:Staphylococcus aureus / Q000276:immunology*; D013997:Time Factors
chemical_list: D000942:Antigens, Bacterial
vernacular_title: Dinamika i faktory reguliatsii gumoral'nogo immunnogo otveta na stafilokokk.