Anterior chamber metastasis from neuroblastoma.
An apparently normal 10-day-old girl had, since birth, a gray-white vascularized tumor in the inferior quadrants of the right anterior chamber. General physical examination revealed abdominal distension, hepatomegaly, splenomegaly, and a deeply located abdominal mass. Multiple subcutaneous nodules scattered all around the body's surface could be palpated. Surgical exploration confirmed the presence of a left adrenal neuroblastoma. Six months after a complete resection of the abdominal tumor and general radiotherapy and chemotherapy, the right anterior chamber mass regressed almost completely, leaving only a calcified residue. The child is living and well six years after the diagnosis of neuroblastoma. This is the first case known to us in the literature of a congenital anterior chamber metastasis, as well as the first case reported of an anterior segment metastasis from a neuroblastoma.
D000310:Adrenal Gland Neoplasms / Q000151:congenital / Q000473:pathology*; D000867:Anterior Chamber; D005134:Eye Neoplasms / Q000151:congenital / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009447:Neuroblastoma / Q000151:congenital / Q000473:pathology*