Disophrol syrup versus Rinomar syrup in the treatment of allergic rhinitis in children.
In this single-blind study, the efficacy and safety of Disophrol Syrup was compared to Rinomar Syrup in seventy-eight paediatric patients with seasonal allergic rhinitis. Patients took 5-10 ml of the randomly assigned medication three to four times daily for a 2-week period. Severity of nasal obstruction, nasal secretion and mucosal swelling was graded and patient response to each week of therapy evaluated. An overall favourable response to Disophrol Syrup was observed in thirty-one out of thirty-five (89%) patients and in thirty out of thirty-five (86%) patients in the Rinomar group. No statistically significant difference in patient response to therapy between treatment groups was noted and no mentionable adverse reactions were reported.
D001977:Brompheniramine / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002936:Cinnarizine / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D004809:Ephedrine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D010665:Phenylpropanolamine / Q000008:administration & dosage / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*
D004338:Drug Combinations; D010879:Piperazines; D011725:Pyridines; D010665:Phenylpropanolamine; D002936:Cinnarizine; C015121:dexbrompheniramine; D004809:Ephedrine; D001977:Brompheniramine