title: [Current therapeutic problems in the Zollinger-Ellison syndrome. Personal cases].
abstract: The topical nature of the treatment of Zollinger-Ellison syndrome arises from the alternatives to total gastrectomy, namely medical management with cimetidine, and tumorectomy. The various stages in the history of the syndrome are described with reference to a personal series of 16 cases, and various observations are made with regard to the clinical aspects of its diagnosis, treatment, and emergency surgical management. A detailed account is given of several illustrative cases. Detailed assessment of the various factors on which the current indications for surgery are based suggests that a certain degree of eclecticism should be adopted, though the results offered by total gastrectomy must be regarded as sound in the long term.
mesh_terms: D000328:Adult; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D005743:Gastrectomy; D005755:Gastrins / Q000097:blood; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D015043:Zollinger-Ellison Syndrome / Q000097:blood / Q000601:surgery / Q000628:therapy*
chemical_list: D005755:Gastrins; D006146:Guanidines; D002927:Cimetidine
vernacular_title: Attualità dei problemi terapeutici nella sindrome di Zollinger-Ellison. Casistica personale.