Quercetin, flavonoids and the life-span of mice.
A dietary supplement of 0.1% quercetin significantly reduced the life span of mice. The effect was predominantly on the 'shorter living' males. A blackcurrant juice extract, containing a mixture of flavonoids in addition to quercetin, prolonged significantly the life span of the 'older dying' females. The significance of these results vis-a-vis aging mechanisms and the dietary intake of quercetin is discussed.
D000818:Animals; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D008136:Longevity / Q000187:drug effects*; D008297:Male; D009115:Muridae; D011794:Quercetin / Q000494:pharmacology*; D012737:Sex Factors
D005419:Flavonoids; D011794:Quercetin