title: Adverse reactions to myelography with metrizamide in infants, children and adolescents. II. Local injury caused by lumbar puncture and injection of contrast medium.
abstract: A series of 605 myelographies with metrizamide was reviewed to assess the risk of local injury caused by the puncture and injection of metrizamide. A lesion below the normal level of the medullary conus was found in 139 patients, and in 10 of these the needle went into or through the lesion. One patient developed paraplegia due to the puncture and injection, no other patient had any symptoms. It is concluded that in spite of the risk, lumbar puncture should be the routine procedure for myelography with metrizamide in children.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008793:Metrizamide / Q000008:administration & dosage / Q000009:adverse effects*; D009192:Myelography / Q000009:adverse effects*; D009339:Needles / Q000592:standards; D010264:Paraplegia / Q000209:etiology; D012306:Risk; D013115:Spinal Canal; D013129:Spinal Puncture / Q000009:adverse effects*
chemical_list: D008793:Metrizamide