Intestinal antisepsis.
The role of antibiotics in large bowel surgery was established by experimental studies indicating that antibiotics could protect a colonic anastomosis subjected to unusual stress. A number of different agents were studied to patients to determine which ones significantly altered the bacterial flora of the colon. Clinical studies were conducted with the agent of choice on the basis of these results. This paper describes a program for preparing patients for elective surgery of the colon.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000985:Antisepsis / Q000379:methods*; D003106:Colon / Q000601:surgery; D004285:Dogs; D006801:Humans; D007410:Intestinal Diseases / Q000517:prevention & control*; D007422:Intestines / Q000382:microbiology; D007612:Kanamycin / Q000627:therapeutic use; D011182:Postoperative Care; D011292:Premedication; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D007612:Kanamycin