Interactions of 2-ppm lead in the water supply with food deprivation upon maze-swimming behavior of mice.
Mice that had been given either tap water or 2 ppm lead in their drinking water and either severely food deprived (3 days before testing) or allowed food ad libitum demonstrated significant interactions of lead treatment by day by food condition and lead by block. Although not statistically significant, the food deprived-lead treated mice displayed more errors and longer latencies than the ad libitum-water controls. The food deprived-water controls and ad libitum-lead-treated mice displayed intermediate values. The importance of using multivariate statistical techniques that can evaluate dynamic repeated behavioral measurements is emphasized.
D000818:Animals; D004193:Discrimination Learning / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects; D004924:Escape Reaction / Q000187:drug effects; D005260:Female; D005508:Food Deprivation; D007855:Lead Poisoning / Q000523:psychology*; D008297:Male; D009115:Muridae; D009949:Orientation / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects; D013550:Swimming