Artificial insemination with fresh donor semen using the cervical cap technique: a review of 278 cases.
Two hundred twenty-six patients received artificial insemination with fresh donor semen (AID) using the cervical cap technique; 52 patients underwent the procedure for 2 conceptions. Using life-table analysis to adjust for uneven patient follow-up, the cumulative pregnancy rate was 62.5% after 6 months of AID, and 82.4% after 10 months. Moreover, using a mathematical model of cumulative pregnancy following AID, the estimated cure rate was not significantly different from 100%, and the estimated monthly probability of pregnancy among those cured was 15.5%. Age was found to be inversely related to pregnancy success, while parity had no effect. For those who continued to undergo AID beyond 6 months, the monthly probability of pregnancy did not decline. Patients can be advised that their chance of conception with AID should approach that of normal fertile couples.
D000328:Adult; D000367:Age Factors; D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000628:therapy; D007315:Insemination, Artificial / Q000379:methods*; D007316:Insemination, Artificial, Heterologous / Q000379:methods*; D008297:Male; D010060:Ovulation; D011247:Pregnancy; D013223:Statistics as Topic; D013997:Time Factors