[Hypolipidemic action of beta-D-glycoside beta-sitosterol in the rat].
In normal animals, administration of beta-D-glycoside does not lead to a decrease in the content of cholesterol and beta-lipoproteins in blood plasma. At the same time the content of phospholipids drops by 38%. During hypercholesterolemia, the drug reduces the content of blood cholesterol by 31% and that of beta-lipoproteins by 46%, as well as normalizes the cholesterol/phospholipid ratio. It is suggested that the drug activates the synthesis of phospholipids in experimental hypercholesterolemia.
D000818:Animals; D002784:Cholesterol / Q000097:blood; D004353:Drug Evaluation, Preclinical; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008077:Lipoproteins, LDL / Q000097:blood; D010743:Phospholipids / Q000097:blood; D051381:Rats; D012855:Sitosterols / Q000627:therapeutic use*
D000960:Hypolipidemic Agents; D008077:Lipoproteins, LDL; D010743:Phospholipids; D012855:Sitosterols; D002784:Cholesterol; C011015:lyoniside
Gipolipidemicheskoe deĭstvie beta-D-glikozida beta-sitosterina u krys.