Sarcoid granuloma of the choroid.
Two patients were found to have macular choroidal granulomas associated with systemic sarcoidosis. This unusual fundus picture was documented by serial fundus photography and fluorescein angiography. Both patients had a similar clinical picture of decreased vision, chorioretinal granulomas, and overlying neurosensory detachments. Staining of the inflammatory mass with fluorescein and leakage of dye into the neurosensory space was typical. Lymph node biopsies were performed to substantiate the diagnosis. Both patients responded promptly to systemic corticosteroid therapy with dramatic improvement in visual acuity and resolution of the choroidal lesions.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002829:Choroid / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D012163:Retinal Detachment / Q000150:complications; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology
D000305:Adrenal Cortex Hormones