[Ability to redistribute surface receptors in transplantable cell lines].
The ability of cultured lymphoid, erythroid and fibroblastic cells for ligand-induced redistribution of their surface receptors proved to be lower than that of lymphocytes. The process of surface receptors redistribution can be inhibited by low temperature and sodium azide in all the cells under study. Pretreatment with trypsin increased the ability for redistribution of surface receptors in some types of cultured cells, but had no such effect on lymphocytes. These differences between lymphocytes and cultured cells seem to be due to differences in organization of the surface and contractile systems of the respective cells.
D000818:Animals; D001386:Azides / Q000494:pharmacology; D002460:Cell Line; D002478:Cells, Cultured; D003208:Concanavalin A / Q000378:metabolism; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D008024:Ligands; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D011952:Receptors, Concanavalin A / Q000187:drug effects / Q000378:metabolism; D011971:Receptors, Immunologic / Q000187:drug effects / Q000378:metabolism*; D019810:Sodium Azide; D013696:Temperature; D014357:Trypsin / Q000494:pharmacology
D001386:Azides; D007106:Immune Sera; D008024:Ligands; D011952:Receptors, Concanavalin A; D011971:Receptors, Immunologic; D003208:Concanavalin A; D019810:Sodium Azide; D014357:Trypsin
Sposobnost' k pereraspredeleniiu poverkhnostnykh retseptorov u kletok perevivaemykh liniĭ.