Copper iontophoresis in male contraception.
Copper was deposited by iontophoresis into vasa deferentia of animals, using 1 m. amp. current for 30-90 sec. in rat and 3 m. amp. current for 60 sec. in rabbits. The method was effective for a period of 9 months as a contraceptive. The effect of the metal was localised at the site of deposition and there was no effect on other reproductive organs. The mating behaviour and testosterone levels did not change. The utility of the technique in male contraception is discussed.
D000818:Animals; D003272:Contraceptive Agents, Male / Q000008:administration & dosage*; D003300:Copper / Q000008:administration & dosage*; D007478:Iontophoresis; D008297:Male; D009929:Organ Size; D011817:Rabbits; D051381:Rats; D013094:Spermatozoa / Q000187:drug effects
D003272:Contraceptive Agents, Male; D003300:Copper