title: Simple method for the screening of polymeric Bence Jones proteins.
abstract: The author tested the electropherograms of previously identified, concentrated urine samples in agarose gel. Before electrophoresis, the gel plate containing the samples was covered with a cellulose-acetate membrane soaked with 0.1 M 2-mercaptoethanol, and it was incubated for 10 min in a moist chamber, at room temperature. If the polymeric Bence Jones protein is present, the electropherogram of the sample changes. In the following, a quick and easy method of recognizing this rare structural anomaly is recommended.
mesh_terms: D001536:Bence Jones Protein / Q000652:urine*; D004587:Electrophoresis, Agar Gel; D006801:Humans; D008623:Mercaptoethanol / Q000494:pharmacology; D010954:Plasmacytoma / Q000175:diagnosis
chemical_list: D008623:Mercaptoethanol; D001536:Bence Jones Protein