title: Ventricular septal defects in three familially-related female Saanen goats.
abstract: Ventricular septal defects were diagnosed in 3 familially-related Saanen goats, a 4-year-old doe and 2 female kids aged 18 weeks, by clinical examination, electrocardiography, phonocardiography and thoracic radiography. Findings were contrasted with those from 3 clinically normal goats. Cardiac catheterisation was attempted on the 2 affected kids before euthanasia. Blood pressure tracings and selective contrast cardioangiography successfully demonstrated the defect in one case, but the other died shortly after anaesthetic induction. The adult goat, suspected paternal grand-dam of the affected twins, died without premonitory signs at 4.5 years of age. Necropsy confirmed the diagnosis in all 3 cases.
mesh_terms: D000818:Animals; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D006041:Goats / Q000235:genetics; D006345:Heart Septal Defects, Ventricular / Q000000981:diagnostic imaging / Q000235:genetics / Q000662:veterinary*; D010701:Phonocardiography / Q000662:veterinary; D011859:Radiography