Content of a cross-reactive idiotype in nonimmune A/J sera.
The anti-p-azophenylarsonate antibodies of A/J mice express a major intrastrain cross-reactive idiotype (CRIA). Using a sensitive radioimmunoassay we were unable to detect significant quantities of molecules bearing CRIA in nonimmune A/J sera. The upper limit is 140 ng/ml. Possible reasons for variability of such data in the published literature are discussed.
D000818:Animals; D003429:Cross Reactions; D007130:Immunoglobulin Idiotypes / Q000276:immunology*; D051379:Mice; D008805:Mice, Inbred A / Q000276:immunology*; D010132:p-Azobenzenearsonate / Q000276:immunology
D007130:Immunoglobulin Idiotypes; D010132:p-Azobenzenearsonate