title: Sclerosing stromal tumor of the ovary.
abstract: This case study of a sclerosing stromal tumor of the ovary in a 29-year-old woman demonstrates that the tumor was a functioning lesion that secreted estradiol, progesterone, and testosterone. Clinically, there was anovulation with resultant infertility, which was resistant to therapy with clomiphene citrate. Removal of the tumor was followed by reversal of these abnormalities.
mesh_terms: D000328:Adult; D000858:Anovulation / Q000209:etiology; D002996:Clomiphene / Q000031:analogs & derivatives / Q000627:therapeutic use; D004715:Endometriosis / Q000150:complications; D004958:Estradiol / Q000378:metabolism; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy / Q000209:etiology; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D010053:Ovary / Q000601:surgery; D011374:Progesterone / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism
chemical_list: D002996:Clomiphene; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol