title: Trichohyaline granules in hair cortex.
abstract: A granular structure was found in the keratogenous zone of the cortex in human hair follicles. This granule was a round, relatively electron-dense, homogeneous structure 0.1-0.3 micron in diameter and not membrane-limited. It appeared in cortical cells in the keratogenous zone, fused to the tonofilaments, and disappeared before the complete keratinization of the cortex. Thus, this granule was considered to be a trichohyaline granule. Similar granules were found in the nuclei of cortical cells in the keratogenous zone. A comprehensive survey of various human hairs confirmed this observation. Trichohyaline granules were also present in the cortical cells of guinea pig hair in the keratogenous zone. However, a similar survey on mouse hair cortex did not reveal trichohyaline granules in this species.
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D006197:Hair / Q000648:ultrastructure*; D006801:Humans; D007381:Intermediate Filament Proteins; D051379:Mice; D008854:Microscopy, Electron; D011498:Protein Precursors / Q000032:analysis*; D013045:Species Specificity
chemical_list: D007381:Intermediate Filament Proteins; D011498:Protein Precursors; C016159:trichohyalin