Glutathione S-transferase activity in liver, lung and intestinal mucosa of aging female mice.
1. Changes in the activity of glutathione S-transferase (GST) in liver, lungs and intestinal mucosa of female Swiss-Webster mice with age were determined. 2. GST activity increased with age from 1 to 9 months, reached a maximum activity at 9 months and decreased thereafter with advanced age in all three tissues. 3. GST activity decreased by approximately 75% in liver between 9 and 18 months, with decreases of 65 and 64% occurring over the same time period for lung and intestinal mucosa, respectively.
D000375:Aging; D000818:Animals; D001835:Body Weight; D003600:Cytosol / Q000201:enzymology; D005260:Female; D005982:Glutathione Transferase / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008168:Lung / Q000378:metabolism*; D051379:Mice; D009929:Organ Size
D005982:Glutathione Transferase