title: [Severe course of a hemolytic-uremic syndrome].
abstract: After an upper respiratory tract infection an eight months old infant developed a severe hemolytic uremic syndrome with anemia, thrombocytopenia and anuria. Remarkable was a lesion of the erythrocytes by neuraminidase producing microorganisms. By early hemodialysis, blood transfusions and accurate fluid therapy the acute stage could be managed. The proceeding course was complicated by hypertension, seizures, coma, abdominal pain attacks and a fibrinous hemorrhagic pericarditis, which made an incomplete pericardectomy necessary. Although it came again to diuresis a severe chronic renal failure with its concluding effects as anemia, acidosis, hypertension and inanition resulted. After a four months period the patient died of biventricular congestive heart failure.
mesh_terms: D003128:Coma / Q000209:etiology; D004912:Erythrocytes / Q000201:enzymology; D006333:Heart Failure / Q000209:etiology; D006463:Hemolytic-Uremic Syndrome / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007223:Infant; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D009439:Neuraminidase / Q000097:blood; D010493:Pericarditis / Q000209:etiology; D012640:Seizures / Q000209:etiology
chemical_list: D009439:Neuraminidase
vernacular_title: Schwerer Verlauf eines hämolytisch-urämischen Syndroms.