Clinical and cerebrospinal fluid findings in lymphocytic meningo-radiculitis (Bannwarth's syndrome).
11 patients with lymphocytic meningo-radiculitis (Bannwarth's syndrome) are described. The disease is characterized by intensive pain, often radiating and migrating, and neurological deficits, i.e. peripheral facial palsies, as well as disseminated radiculopathies. In 4 patients the onset was preceded by an arthropod bite, close to which 3 patients exhibited an erythema chronicum migrans. In the cerebrospinal fluid there was a mononuclear pleocytosis, predominantely by lymphocytes. In the early stages, a plasma cell reaction was frequently encountered. Protein analysis indicated a defect in the blood brain barrier and an intrathecal synthesis of IgG. All patients recovered almost completely from their neurological symptoms within 1-2 months, irrespective of treatment.
D000328:Adult; D000368:Aged; D001812:Blood-Brain Barrier; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008218:Lymphocytosis / Q000134:cerebrospinal fluid*; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid*; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D010950:Plasma Cells / Q000648:ultrastructure; D011843:Radiculopathy / Q000134:cerebrospinal fluid*; D012709:Serum Albumin / Q000134:cerebrospinal fluid; D013548:Sweden; D013577:Syndrome
D007074:Immunoglobulin G; D012709:Serum Albumin