title: [Identification of estrogen-binding proteins in the human liver].
abstract: Several properties of estradiol (E2)-binding cytosol macromolecules in the liver of females with cholecystitis and of males with hepatic cirrhosis were studied by means of comparatively delicate methods of free- and bound hormone separation. E2-binding macromolecules with Stokes' radius of approximately 5 nm were found in the hepatic samples under study, formed with E2 complexes, similar to estrogen receptors, according to hormonal specificity of affinity and stability. Protein, similar to a specific estrogen-binding protein of the rat and guinea pig liver, was not found in the preparations examined.
mesh_terms: D000328:Adult; D002352:Carrier Proteins / Q000032:analysis*; D002764:Cholecystitis / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008103:Liver Cirrhosis / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011485:Protein Binding; D011960:Receptors, Estrogen / Q000032:analysis*
chemical_list: D002352:Carrier Proteins; D004967:Estrogens; D011960:Receptors, Estrogen; C010140:estrophilin
vernacular_title: Identifikatsiia éstrogensviazyvaiushchikh belkov v pecheni cheloveka.