[Effect of L-DOPA on the emotional, behavioral and autonomic manifestations of acute nociceptive exposure].
Experiments on conscious cats have demonstrated that L-DOPA (25-50 mg/kg) does not change behavioral reactions evoked by dental pulp stimulation. L-DOPA (50 mg/kg) causes bradycardia accompanied by the increase in the cardiochronotropic baroreceptor reflex, inhibits the pressor and enhances heart rate nociceptive reactions. The effect of L-DOPA on the heart rate and baroreceptor reflexes is reversed by preliminary inhibition of peripheral DOPA-decarboxylase with benserazide (30 mg/kg).
D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects*; D001522:Behavior, Animal / Q000187:drug effects*; D002415:Cats; D003782:Dental Pulp / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D004644:Emotions / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D007980:Levodopa / Q000494:pharmacology*; D009619:Nociceptors / Q000187:drug effects*
D007980:Levodopa
Vliianie L-DOFA na émotsional'no-povedencheskie i vegetativnye proiavleniiia ostrogo notsitseptivnogo vozdeĭstviia.