Self-replication with errors. A model for polynucleotide replication.
A model for polynucleotide replication is presented and analyzed by means of perturbation theory. Two basic assumptions allow handling of sequences up to a chain length of v approximately 80 explicitly: point mutations are restricted to a two-digit model and individual sequences are subsumed into mutant classes. Perturbation theory is in excellent agreement with the exact results for long enough sequences (v greater than 20).
D004261:DNA Replication; D008433:Mathematics; D008957:Models, Genetic; D009154:Mutation; D011119:Polynucleotides; D014158:Transcription, Genetic
D011119:Polynucleotides