title: Effects of selective injection of contrast media on coronary artery diameter.
abstract: The purpose of this study was to quantify the effect of Renografin-76 on epicardial coronary artery diameters, during selective coronary angiography. Using 105 mm-photospot angiograms taken at 0, 1, and 5 min, 99 coronary segments from ten patients were measured. Comparing the angiograms at 1 and 5 min to the control angiograms, a 7 +/- 7% and 6 +/- 7% (both p = NS) change in diameter respectively was noted. Comparing the 1 and 5 min angiograms, there was no significant change (-1 +/- 7%). Measurements were found to be very reproducible. This study shows that there is a trend toward dilation of the coronary arteries during selective coronary angiography, but this did not reach statistical significance and probably is not clinically important.
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D006328:Cardiac Catheterization / Q000009:adverse effects; D003326:Coronary Circulation / Q000187:drug effects; D003331:Coronary Vessels / Q000187:drug effects*; D003973:Diatrizoate / Q000008:administration & dosage* / Q000031:analogs & derivatives* / Q000494:pharmacology; D003974:Diatrizoate Meglumine / Q000008:administration & dosage* / Q000494:pharmacology; D004338:Drug Combinations / Q000008:administration & dosage / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D013268:Stimulation, Chemical
chemical_list: D004338:Drug Combinations; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; C027278:urovision