[Metabolism of Ca-45 in the blood vessels and heart of rats with spontaneous hypertension].
The uptake of 45Ca was increased in the hypertrophic left ventricle of the heart of young (6-7 week) spontaneously hypertensive rats (SHR) at the prehypertensive stage, while at the stage of persistent hypertension (24-26-week SHR), the 45Ca uptake was only increased in the aorta and tail artery. The rates of 45Ca elimination from the vessels of mature SHR proved to be considerably elevated, and those of young SHR unchanged, as compared to the control animals. The findings obtained point to a close association between disorders in vascular and cardiac 45Ca metabolism and the development of hypertension in SHR.
D000818:Animals; D001011:Aorta / Q000378:metabolism*; D001158:Arteries / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D002132:Calcium Radioisotopes; D005260:Female; D006973:Hypertension / Q000378:metabolism*; D066298:In Vitro Techniques; D008657:Metabolic Clearance Rate; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012447:Sacrum / Q000098:blood supply*
D002132:Calcium Radioisotopes; D002118:Calcium
Obmen 45Ca v sosudakh i serdtse krys so spontannoĭ gipertenzieĭ.