title: Nissen-Rossetti fundoplication for the treatment of gastro-oesophageal reflux.
abstract: During 1978 and 1979 20 patients were subjected to fundoplication. All these patients had abnormal oesophageal acid reflux as demonstrated by 18-hour pH-monitoring of the distal oesophagus. They had also complications of this reflux, i.e. oesophageal ulcerations or stricture formation. The patients were reexamined two months postoperatively and 5-22 (mean 13.3) months after operation. The patients' satisfaction was high after operation and the oesophagitis was cured in all. The oesophagus was lengthened from 35.8 +/- S.D. 1.85 cm to 38.7 +/- S.D. 2.25 cm after fundoplication (p less than 0.05) as measured by endoscopy. The mechanism of success of this operation may be related to the return of LES to the intra-abdominal compartment, but also a flutter valve mechanism may be operative.
mesh_terms: D000328:Adult; D003258:Consumer Behavior; D003680:Deglutition Disorders / Q000209:etiology; D003967:Diarrhea / Q000209:etiology; D004945:Esophagoscopy; D005069:Evaluation Studies as Topic; D005260:Female; D005414:Flatulence / Q000209:etiology; D005764:Gastroesophageal Reflux / Q000150:complications / Q000601:surgery*; D006356:Heartburn / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications