title: A high pressure liquid chromatographic procedure for monitoring 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea levels in body fluids.
abstract: A reverse phase high pressure liquid chromatographic method has been developed for the analysis of 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) levels present in body fluids. A value obtained for the plasma half-life for a single patient indicates that this may be larger than hitherto expected.
mesh_terms: D001826:Body Fluids / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D009607:Nitrosourea Compounds / Q000032:analysis*; D012673:Semustine / Q000032:analysis* / Q000097:blood / Q000652:urine
chemical_list: D009607:Nitrosourea Compounds; D012673:Semustine