[Biological variants of a population of strains of the rabies street virus].
Experiments in mice weighing 6-7 g showed that a population of wild street rabies virus strains could contain from 1 to 3 biologic variants determining the clinical characteristics, duration of the incubation period and of the disease, and virus titres in the brain. Fox strains L-1 and L-2 produced only paralytic rabies, the BE strain isolated from a badger induced paralytic and chronic disease, and the population of the Yak strain isolated from a boy bitten by a fox and timely given a complete course of postexposure treatment contained 3 biologic variants: (1) VAR produced acute paralytic rabies throughout 59 passages, (2) VVR induced a disease of the type of "violent" rabies throughout 20 passages, and (3) VCR provoked chronic rabies in 27 passages.
D000818:Animals; D001921:Brain / Q000382:microbiology; D002648:Child; D005589:Foxes / Q000382:microbiology; D006801:Humans; D008297:Male; D051379:Mice; D010243:Paralysis / Q000382:microbiology; D011818:Rabies / Q000145:classification / Q000382:microbiology; D011820:Rabies virus / Q000145:classification / Q000302:isolation & purification / Q000472:pathogenicity*; D013997:Time Factors
Izuchenie biologicheskikh variantov populiatsii riada shtammov ulichnogo virusa beshenstva.