[Closure of pleura and lung lesions with fibrin adhesive. Experimental studies].
The effect of the fibrin adhesive on the gas density of pleura-lung-sutures was investigated in 28 male Wistar rats. Standardized pleura-lung-lacerations were closed by additional fibrin adhesive application in combination with fibrinolytic inhibitors. 30 minutes and 5 days after operation the animals were sacrificed and manometric and micromorphological examinations performed. In good histo-compatibility the additional application of the fibrin adhesive proved to be a proper technique in elevating the pressure tolerance of pleura-lung-sutures significantly.
D000818:Animals; D005337:Fibrin / Q000627:therapeutic use*; D006648:Histocompatibility; D006801:Humans; D008168:Lung / Q000601:surgery*; D055370:Lung Injury; D008297:Male; D010994:Pleura / Q000293:injuries / Q000601:surgery*; D051381:Rats; D011919:Rats, Inbred Strains; D013529:Surgical Wound Dehiscence / Q000453:epidemiology; D013537:Sutures; D014014:Tissue Adhesives
D014014:Tissue Adhesives; D005337:Fibrin
Verschluss von Pleura-Lungen-Läsionen mittels Fibrinklebung. Experimentelle Untersuchungen.