Metronidazole treatment of bypass-enteropathy after jejunoileal shunt-operation for obesity.
In 5 patients with bypass-enteropathy following jejunoileal shunt-operation for morbid obesity, bacterial overgrowth was demonstrated in the functioning small bowel. The symptoms were effectively relieved during treatment with metronidazole in the 3 patients, who completed the treatment. Bacterial cultures revealed no anaerobic growth during 3 of 4 periods of treatment. Anaerobic overgrowth in the small bowel is probably the cause of bypass-enteropathy following jejunoileal shunt-operation.
D000328:Adult; D001442:Bacteroides Infections / Q000188:drug therapy; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011183:Postoperative Complications
D008795:Metronidazole