Neurophysiological mechanism of shrinkage of nasal mucosa induced by exercise.
Change of serum norepinephrine level and nasal patency were measured in 10 normal volunteers during exercise and effect of unilateral cervical sympathetic ganglion block on exercise-induced shrinkage of nasal mucosa was evaluated. Serum norepinephrine elevated markedly after 10-min exercise. Unilateral blocking of cervical ganglion completely inhibited mucosal shrinkage induced by exercise in 8 of 10 subjects. Mucosal shrinkage during exercise in these subjects was assumed to be mediated through cervical sympathetic ganglion, and not by increase in circulating cathecolamine. However, in 2 subjects, moderate shrinkage of the nasal mucosa was observed in 10-min after initiation of exercise. It was impossible to rule out some effect of circulating cathecolamine on the capacitance vessels of the nasal mucosa completely.
D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D000818:Animals; D001340:Autonomic Nerve Block; D001794:Blood Pressure; D004285:Dogs; D005728:Ganglia, Sympathetic / Q000502:physiology; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000502:physiology*; D009638:Norepinephrine / Q000097:blood; D005082:Physical Exertion
D009638:Norepinephrine