Studies on a new antibiotic M-92 produced by Micromonospora. I. Taxonomy of M-92 producing Micromonospora and antibiotic production therefrom.
An isolate (strain MCRL 0404) producing a new antibiotic, M-92, was identified as a new strain of Micromonospora for which the name Micromonospora verruculosa sp. nov. was proposed. A water-infusion of dried sea tangle and dried shiitake was utilized for the production of M-92. When this strain was fermented in the medium containing this infusion, M-92 accumulated in the mycelium at about 10 times that in the broth at the peak level.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D005285:Fermentation; D008847:Micromonospora / Q000145:classification* / Q000302:isolation & purification / Q000378:metabolism; D008854:Microscopy, Electron; D009285:Naphthoquinones / Q000096:biosynthesis
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C036968:M 92