Gas chromatographic determination of drug levels for the evaluation of a combined hemoperfusion-hemodialysis treatment.
Recently, the use of a prolonged and combined procedure of hemoperfusion (HP) and hemodialysis (HD) was considered as a treatment for severely intoxicated patients caused by drug overdose. Working in cooperation with different hospitals, this laboratory has been involved with the toxicological analysis of biological samples taken during such a treatment. This paper describes the use of a combined HP/HD treatment, especially the evaluation of the system, by giving the analytical results obtained by gas chromatography. The methods utilized enable this application for routine toxicological analysis.
D000328:Adult; D000438:Alcohols / Q000032:analysis; D001463:Barbiturates / Q000032:analysis; D002849:Chromatography, Gas; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000097:blood / Q000652:urine; D011041:Poisoning / Q000378:metabolism / Q000628:therapy*; D006435:Renal Dialysis
D000438:Alcohols; D001463:Barbiturates; D004364:Pharmaceutical Preparations