title: Meiotic nondisjunction in male Snell dwarf mice.
abstract: Male hypopituitary Snell dwarf mice showed significantly more autosomal univalents in diakinesis-metaphase I (7.75 percent) and more anaphase I nondisjunction (2.68 percent) than normal mice (autosomal univalents: 4.9 percent; nondisjunction: 1.00 percent). The values of male dwarf mice, artificially made hyperthyroid, were between values of untreated dwarfs and normals (autosomal univalents: 5.25 percent; nondisjunction: 2.25 percent), but could not be shown to differ significantly from either value.
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000648:ultrastructure; D004392:Dwarfism / Q000235:genetics; D007018:Hypopituitarism / Q000235:genetics*; D008297:Male; D008540:Meiosis; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D009630:Nondisjunction, Genetic; D013094:Spermatozoa / Q000648:ultrastructure; D013577:Syndrome; D013974:Thyroxine / Q000494:pharmacology
chemical_list: D013974:Thyroxine