[Protective effect of heparin and phosphatidylserine in exogenous thromboplastinemia].
It was shown in experiments on rats that heparin and phosphatidylserine-containing anticoagulant increase the animals' tolerance to thromboplastin administration to the blood flow. This is manifested by a considerable lowering of the death rate and restriction of fibrinogen consumption caused by thromboplastin. It was ascertained that the protective effects of heparin and phosphatidylserine are drastically potentiated during combined administration, apparently because of the influence of the anticoagulants on different stages of fibrin formation.
D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004357:Drug Synergism; D006493:Heparin / Q000627:therapeutic use*; D010718:Phosphatidylserines / Q000627:therapeutic use*; D051381:Rats; D013925:Thromboplastin / Q000008:administration & dosage*; D013997:Time Factors
D000925:Anticoagulants; D010718:Phosphatidylserines; D006493:Heparin; D013925:Thromboplastin
Zashchitnyĭ éffekt geparina i fosfatidilserina pri ékzogennoĭ tromboplastinemii.