Relationship between preoperative basal serum gastrin concentration and acid secretion after proximal gastric vagotomy.
In 81 patients with duodenal ulcer, the preoperative basal serum gastrin concentration was positively correlated to basal acid output after proximal gastric vagotomy and negatively correlated to the decrease in basal acid output exerted by the operation. The preoperative basal concentration of gastrin in serum was found to distinguish between high and low basal acid output after operation, 40 pg/ml being the discriminatory level.
D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000097:blood / Q000628:therapy; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005745:Gastric Acidity Determination; D005755:Gastrins / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014628:Vagotomy; D014629:Vagotomy, Proximal Gastric
D005755:Gastrins