The development of neurogenic vesical dysfunction after experimental spinal cord injury or sacral rhizotomy in non-human primates.
Vesical and urethral function were studied urodynamically before and after spinal cord or sacral root injury in non-human primates. Detrusor sphincter discoordination developed in animals with complete suprasacral spinal cord injury. Animals subjected to complete intradural sacral rhizotomy developed hypertonic areflexic vesical dysfunction while those subjected to dorsal root ganglionectomy developed a high compliance low pressure bladder.
D000818:Animals; D005260:Female; D005727:Ganglia, Spinal / Q000502:physiology; D008252:Macaca fascicularis; D008297:Male; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000502:physiology; D011312:Pressure; D013119:Spinal Cord Injuries / Q000150:complications*; D013126:Spinal Nerve Roots / Q000502:physiology; D013562:Sympathectomy; D001743:Urinary Bladder / Q000294:innervation; D001750:Urinary Bladder, Neurogenic / Q000209:etiology*; D014563:Urodynamics