title: Anti-diarrhoeal drugs.
abstract: Drugs that have been used or investigated in the treatment of diarrhoea in infancy were presented, such as stool thickening agent kaolin-pectin, anti-motility agent loperamide, anti-secretory agents such as chlorpromazine, aspirin, indomethacin, and antibiotics. Also treatment with oral rehydration solution was discussed from studies carried out. The present clinical studies demonstrate that most of anti-diarrhoeal drugs are not superior than the usual mode of fluid therapy in the treatment of infantile diarrhoea. The use of these anti-diarrhoeal drugs in the community, therefore, should be considered carefully since they may distract from the essential treatment--oral rehydration.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000930:Antidiarrheals / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use; D002746:Chlorpromazine / Q000627:therapeutic use; D002792:Cholestyramine Resin / Q000627:therapeutic use; D003968:Diarrhea, Infantile / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007616:Kaolin / Q000627:therapeutic use; D008139:Loperamide / Q000627:therapeutic use; D010368:Pectins / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000930:Antidiarrheals; D002792:Cholestyramine Resin; D007616:Kaolin; D008139:Loperamide; D010368:Pectins; D001241:Aspirin; D002746:Chlorpromazine