Unusual presentation of head and neck neoplasm.
We have a 67-year-old Caucasian male presenting with a (T4, N1b, Mo) Stage III squamous cell carcinoma of the larynx. He subsequently underwent a total laryngectomy and right radical neck dissection. It was only determined by the pathology report that the cervical nodes in the neck specimen obtained the associated disease, Hodgkin's (mixed cellular lymphoma), rather than the expected well differentiated squamous cell carcinoma found in the larynx. Metastatic work-up was unrevealing. Reviewing the English literature fails to reveal a similar case report of squamous cell carcinoma of the larynx with Hodgkin's disease in the associated neck dissection. It was unfortunate that this patient died of a third pathology, cerebral hemorrhage, in the immediate post-op period.
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology*; D006689:Hodgkin Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D009333:Neck