[Lactate dehydrogenase activity and isoenzyme spectrum in the transplanted sensory and sympathetic ganglia of the rat].
Total activity, isoenzyme pattern of lactate dehydrogenase (LDH), morphological peculiarities of normal and transplanted in the mesentery for 1-7 and 30 days dorsal root and superior cervical sympathetic ganglia of the adult rats, were analysed. About 30% neurons in sensory ganglia and 5% in sympathetic ganglia were viable 30 days after transplantation. Total LDH activity was 3 times higher in normal sympathetic ganglia compared with that in spinal ganglia. Transplantation leads to a slight rising in total LDH activity in sensory root ganglia and to a slight fall in sympathetic ganglia. Five fractions of LDH in normal sensory ganglia and four fractions in sympathetic ganglia were revealed. Significant rising of M4 isoenzyme activity was characteristic of both sensory and sympathetic ganglia after transplantation for 7 days. Functional significance of the changes observed is discussed.
D000693:Anaerobiosis; D000818:Animals; D005727:Ganglia, Spinal / Q000201:enzymology* / Q000473:pathology / Q000637:transplantation; D005728:Ganglia, Sympathetic / Q000201:enzymology / Q000473:pathology / Q000637:transplantation; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D008643:Mesentery; D051381:Rats; D011919:Rats, Inbred Strains
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Aktivnost' i izofermentnyĭ spektr laktatdegidrogenazy transplantirovannykh sensornykh i simpaticheskikh gangliev krysy.