title: Effects on visual acuity of neonatal or adult tectal ablation in rats.
abstract: Tectal ablation in neonatal rats leads to retrograde degeneration of retinal ganglion cells whereas similar damage in adults does not. We show here that the behavioral effects are comparably different. When rats with neonatal tectal ablation are tested as adults they are impaired in learning a discrimination between vertical and horizontal stripes and their visual acuity for square-wave gratings is slightly but significantly reduced.
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D004193:Discrimination Learning / Q000502:physiology; D008297:Male; D009897:Optic Chiasm / Q000502:physiology; D009900:Optic Nerve / Q000502:physiology; D051381:Rats; D012165:Retinal Ganglion Cells / Q000502:physiology; D013477:Superior Colliculi / Q000502:physiology*; D014792:Visual Acuity; D014795:Visual Pathways / Q000502:physiology; D014796:Visual Perception / Q000502:physiology