title: [Drug therapy of neurogenic bladder with the alpha-receptor blocker phenoxybenzamine].
abstract: A report is given on the results of therapy with the alpha-adrenolytic phenoxybenzamine in 36 patients in a rehabilitation centre for paraplegics. The sole indication for using the preparation was neurogenously disturbed micturition with large quantities of residual urine. The best therapeutic results--i.e. reduction of residual urine to 60 ml or less--were achieved in patients with lesions of the lower motoric neuron (15 patients) and the upper motoric neuron in the region L2-S2 (1 patient). The results in cases of lesion in the region Th10-L2 (3 patients) were so bad that the application of the preparation cannot be recommended in such cases. In cases of paralysis of the thoracic cord and the cervical part of the medulla (14 patients) 50% of the results were good and 35% were bad.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008875:Middle Aged; D010264:Paraplegia / Q000150:complications; D010643:Phenoxybenzamine / Q000627:therapeutic use*; D013119:Spinal Cord Injuries / Q000150:complications; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*
chemical_list: D010643:Phenoxybenzamine
vernacular_title: Medikamentöse Therapie der neurogenen Blase mit dem alpha-Rezeptorenblocker Phenoxybenzamin.