title: Age-related differences in healing of superficial skin wounds in humans.
abstract: The healing response of human volunteers was measured by monitoring the reestablishment of skin surface markings in unroofed blisters induced by brief exposure to a 1:1 aqueous solution of ammonium hydroxide. At all stages of repair, older individuals (ages 65-75 years) as a group lagged behind young adults (ages 18-25 years). Although individuals differed appreciably, especially in the older cohort, there was a good correlation between the rate of repair at two protected sites, the inner upper arm and the volar forearm. This suggests that healing response may a reliable measure of the physiologic status of the skin.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D064753:Ammonium Hydroxide; D001768:Blister / Q000139:chemically induced / Q000503:physiopathology; D006801:Humans; D006878:Hydroxides; D012867:Skin / Q000503:physiopathology*; D014945:Wound Healing
chemical_list: D006878:Hydroxides; D064753:Ammonium Hydroxide