title: [Recovery from anesthesia with enflurane and neuroleptanesthesia. Quantitative assessment with the aid of psychopathometric tests].
abstract: Methodological differences between techniques used to examine recovery from anesthesia prevent direct comparison of results. Also psychological tests are not validated for certain anaesthesiological considerations. The two tests presented here combine ease of use for a bedside test with the advantage that the results are expressed as absolute values of cerebral depression. Based on Wieck's concept of symptomatic or functional psychosis they were developed to document the course of neuropsychiatric illness. Their application following anaesthesia seems to be justified as anaesthesia may be regarded as being a deliberately induced functional psychosis characterized by extremely compressed dynamics. The target of a first pilot study were 60 patients following neuroleptanalgesia with and without antagonization with naloxone, or enflurane anaesthesia, respectively. Psychopathometric evaluation yielded an obvious post-operational decline in the SKT-scores which clearly remained below the pre-operative values even after three hours. All the patients revealed a severe transient syndrome after thirty minutes, a moderate syndrome after one and two hours and a mild syndrome after three hours. The only exception were patients antagonized with naloxone who initially showed an improvement but who afterwards did not behave any better. Neither duration of anaesthesia nor total dose of drugs administered showed any significant correlation to the extent of postoperative cerebral depression. Being uninfluenced by moderating variables such as age and IQ, the psychopathometric tests presented here seem to provide a sensitive and reliable method for quantification of recovery from anaesthesia.
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D000758:Anesthesia / Q000009:adverse effects; D004737:Enflurane / Q000009:adverse effects; D006801:Humans; D007361:Intelligence Tests; D008875:Middle Aged; D009270:Naloxone / Q000494:pharmacology; D009458:Neuroleptanalgesia / Q000009:adverse effects; D011184:Postoperative Period; D011569:Psychiatric Status Rating Scales; D011605:Psychoses, Substance-Induced / Q000209:etiology
chemical_list: D009270:Naloxone; D004737:Enflurane
vernacular_title: Das Aufwachverhalten nach Enflurane-Narkose und Neurolept-Anaesthesie. Quantitative Bewertung mit Hilfe psychopathometrischer Teste.