title: Proton cycling through the mitochondrial phosphate transporter in energy transduction.
abstract: The molecular structure of the phosphate carrier of mitochondria is probably controlled by the H+ ion concentration within the matrix. It is supposed that changes in molecular structure affect the H+- and H2PO4- ion transporting function and may be part of the "gating" mechanism in phosphate transport.
mesh_terms: D000818:Animals; D001419:Bacteria / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D004228:Dithionitrobenzoic Acid / Q000494:pharmacology; D005033:Ethylmaleimide / Q000494:pharmacology; D007700:Kinetics; D008928:Mitochondria / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D028044:Phosphate-Binding Proteins; D011188:Potassium / Q000494:pharmacology; D051381:Rats; D014634:Valinomycin / Q000494:pharmacology
chemical_list: D002352:Carrier Proteins; D028044:Phosphate-Binding Proteins; D014634:Valinomycin; D004228:Dithionitrobenzoic Acid; D005033:Ethylmaleimide; D011188:Potassium