Epidemiological study and comparison of pyrantel and levamisole in the treatment of roundworm and hookworm infestations.
Stool examined for presence of nematodes from 467 school students in Dacca city showed 48% ova positive cases with 22% among them cases of mixed nematode infection. Highest prevalence of 58% was observed with roundworm and 5% was hookworm infestations. Among hookworm cases, Necator americana (68%) appears to be the predominant species. Two anthelmintics-pyrantel and levamisole achieved similar high cure rate (around 97%) and Egg reduction rate of 99% in roundworm infection. However, pyrantel was observed to be more effective in hookworm infestation (87% against 60%) particularly in Necator americana cases.
D000293:Adolescent; D000328:Adult; D001459:Bangladesh; D002648:Child; D006725:Hookworm Infections / Q000188:drug therapy*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D010270:Parasite Egg Count; D011715:Pyrantel / Q000627:therapeutic use*
D007978:Levamisole; D011715:Pyrantel