Sarubicin b, a new quinone antibiotic, isolated from the fermentation broth of a streptomyces strain.
Sarubicin B, isolated from the culture filtrate of a Streptomyces strain JA 2861, is a new quinone antibiotic. The compound was isolated as an orange crystalline powder, mp 282 approximately 284 degrees C. In vitro sarubicin B was found to inhibit Gram-positive bacteria. It was not active against Gram-negative microorganisms.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005285:Fermentation; D013058:Mass Spectrometry; D009285:Naphthoquinones / Q000096:biosynthesis / Q000494:pharmacology; D013302:Streptomyces / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C037256:sarubicin B