Covalent binding of a neurotoxic n-hexane metabolite: conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione.
D000588:Amines / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002645:Chickens; D002863:Chromogenic Compounds; D005260:Female; D006586:Hexanes / Q000378:metabolism / Q000633:toxicity*; D006588:Hexanones / Q000378:metabolism*; D007659:Ketones / Q000378:metabolism*; D009422:Nervous System Diseases / Q000139:chemically induced*; D011506:Proteins / Q000378:metabolism; D011758:Pyrroles / Q000378:metabolism*
D000588:Amines; D000596:Amino Acids; D002863:Chromogenic Compounds; D006586:Hexanes; D006588:Hexanones; D007659:Ketones; D011506:Proteins; D011758:Pyrroles; C026385:n-hexane; C011269:2,5-hexanedione; C027764:2,4-hexanedione