[Prevalence of diabetes mellitus and glucose tolerance abnormality in Melanesians and subjects of Polynesian descent in the rural areas of New Caledonia and at Ouvea (Loyalty Islands)].
The screening of different ethnic groups who live in the same natural system have enabled the authors to study interaction between genetic and environmental factors as a part of etiology of diabetes mellitus. In New Caledonian country areas, the prevalences of glucose tolerance abnormality (GTA) and diabetes mellitus (DM) have been higher with people of polynesian descent than with Melanesians. GTA 7.6 p. ct. versus 5.1 p. ct. DM 6.5 p. ct. versus 2.2 p. ct. The prevalence of these combined diseases have been 14 p. ct. with the Polynesians and 7.2 p. ct. with Melanesians. These two ethnic groups have shown mean ages and obesity rates similar enough to lead the authors to deny these two factors a major part in the difference between the ethnic prevalences of DM. Besides, the mean plasmatic glycemia two hours after a dose of glucose and the relative risk of DM and GTA according to age and obesity rate have shown that the slight differences between these groups are not involved in the different prevalences of DM. This inter-ethnic difference may be due to genetic factors. However, some environment linked factors besides obesity (such as diet and daily life activity) may share a major part in this difference.
D000328:Adult; D000368:Aged; D044383:Black People; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008542:Melanesia; D008875:Middle Aged; D009510:New Caledonia; D009765:Obesity / Q000453:epidemiology; D011114:Polynesia / Q000208:ethnology; D012424:Rural Population; D044465:White People
D001786:Blood Glucose
Prévalence du diabète sucré et de l'anomalie de la tolérance au glucose chez les Mélanésiens et les sujets d'origine polynésienne dans les zones rurales de Nouvelle-Calédonie et à Ouvea (Iles Loyauté).