[Direct relation between the significantly increased IgG specific antibody titer and the clinico-evolutive form in respiratory infections in infants and children. IgA and IgD levels in the evolution].
Of 69 children suffering from acute respiratory infections, with increased IgG titers 34 presented normal or high IgAs titers in the laryngotracheal exudate. All these patients had a favourable evolution. The other children with low IgAs levels or absent IgAs in the laryngotracheal exudate had a prolonged relapsing evolution, regardless of serum IgG levels. The presence of IgA 7S in the laryngotracheal exudate did not influence the course of the disease. As a conspicuous parallelism was observed between laryngotracheal exudate IgAs and serum IgA it was assumed that IgAs participates in the formation of serum IgA "mixtures". Increased IgD values were found in 34 of these patients, ten of whom presented respiratory allergy and recurrent infections.
D000293:Adolescent; D000906:Antibodies / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007072:Immunoglobulin D / Q000032:analysis*; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000276:immunology*
D000906:Antibodies; D007070:Immunoglobulin A; D007072:Immunoglobulin D; D007136:Immunoglobulins
Relaţii directe între titrul anticorpilor specifici IgG crescuţi semnificativ şi forma clinico-evolutivă în infecţiile respiratorii la sugar şi copil. Nivelurile IgAs şi IgD legate de evoluţie.