Protein adsorption in vitro onto biomaterial surfaces covered with ULTI carbon.
A study is presented which describes the adsorption in vitro of albumin and fibrinogen onto a mini-shunt oxygenation unit. The unit is characterized by flow through 10 etched microchannel conduits with a microporous membrane and conduits are pretreated with a uniform layer of ULTI carbon and evaluated for the steady-state and time varying kinetics of protein adsorption. Corresponding results for oxygenator components not pretreated with ULTI carbon are also included.
D000327:Adsorption; D001672:Biocompatible Materials / Q000494:pharmacology*; D001777:Blood Coagulation; D002244:Carbon / Q000378:metabolism*; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D010107:Oxygenators, Membrane; D012709:Serum Albumin / Q000378:metabolism*; D013997:Time Factors
D001672:Biocompatible Materials; D012709:Serum Albumin; D002244:Carbon; D005340:Fibrinogen