Determinants of high density lipoprotein and total cholesterol in women.
An epidemiological study was carried out among a random sample of women aged 18 to 69 years to examine possible determinants of plasma high density lipoprotein and total cholesterol (HDL-C and T-C). In a multiple regression analysis consumption of alcohol, fatty fish, and parental longevity showed positive associations with HDL-C, which were statistically significant. Smoking habit, sucrose consumption, and a family history of ischaemic heart disease showed significantly negative associations. In contrast, T-C was associated significantly only with age and Quetelet's index of body mass. Five variables having significant associations with HDL-C explained only 8% of the total variance; in the case of T-C 17% of the variance was explained by age and body mass.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL; D003327:Coronary Disease / Q000235:genetics; D004032:Diet; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood*; D008136:Longevity; D008875:Middle Aged; D010290:Parents; D010808:Physical Examination; D012907:Smoking
D008076:Cholesterol, HDL; D008075:Lipoproteins, HDL; D002784:Cholesterol