Genetic variation of pepsinogen 1 in the rat.
A pepsinogen (Pg 1) polymorphism was observed in gastric mucosal samples of Wistar rats by polyacrylamide slab gel electrophoresis. Three phenotypes were observed: S (a slow-moving band), F (a fast-moving band), and FS (both bands). Pg 1 variation was controlled by a pair of codominant alleles at a single autosomal locus. Interstrain variation of Pg 1 was studied in five strains of laboratory rats. Genetic variation of Pg 1 was detected only in the Wistar strain.
D000483:Alleles; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005753:Gastric Mucosa / Q000032:analysis; D014644:Genetic Variation; D010435:Pepsinogens / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*
D010435:Pepsinogens