The leukocyte adherence inhibition test in tumor patients using 3M KCl extracts of fetal tissues as antigens.
The sensitization of tumor patients was evaluated with the LAI test to 3M KCl extracts of human fetuses derived from abortion in the 1st-3rd month, 5th month and 7th month of pregnancy. Positive responses were seen against preparations from fetuses at different developmental stages: reactivity was found among 12/18 (1st-3rd month), 13/15 (5th month) and 14/16 (7th month) of the tumor patients. In total, 80% (39/49) of the patients were sensitized to fetal extracts. In contrast, only 19% (10/54) of the control group reacted positively in the LAI test.
D000941:Antigens / Q000302:isolation & purification; D004622:Embryo, Mammalian; D005260:Female; D005333:Fetus / Q000276:immunology*; D005865:Gestational Age; D006801:Humans; D007957:Leukocyte Adherence Inhibition Test; D009369:Neoplasms / Q000276:immunology*; D009928:Organ Specificity; D011189:Potassium Chloride; D011247:Pregnancy
D000941:Antigens; D011189:Potassium Chloride