A comparative study of the morbidity associated with sickle cell anemia among patients in Ibadan (Nigeria) and Oakland (U.S.A.).
A cohort of 60 matched pairs of sickle cell anemia patients from Ibadan (Nigeria) and Oakland CA., USA, were compared in a follow up study. The null hypothesis tested was that there was no significant difference in the morbidity associated with sickle cell anemia among Ibadan SS patients receiving antimalaria prophylaxis, and Oakland SS patients. Proportions of outpatient clinic visits due to "crisis"; "SS-associated-infections"; "infections not associated with sickle cell anemia"; "routine follow up"; and "others" were used as measures of morbidity. The results showed that the proportion of clinic visits due to "crisis" and "SS associated infections" were not significantly different (p greater than 0.05) among both groups of patients. Occasional variations were found between mean proportions of the clinic visits due to "infections not associated with SS"; "follow up" and "others".
D000755:Anemia, Sickle Cell / Q000453:epidemiology*; D002140:California; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007239:Infections / Q000453:epidemiology; D008297:Male; D009017:Morbidity; D009549:Nigeria