Effectiveness of generic acetazolamide.
Comparisons were made between the ocular hypotensive effects and blood levels achieved with the single-dose administration of either generic acetazolamide or brand-name acetazolamide (Diamox). The relative cost of the two products was surveyed. The effect of food on the absorption of acetazolamide was also evaluated. The generic and brand-name acetazolamide were equivalent in their effects on intraocular pressure. Comparable blood levels of acetazolamide were obtained with the two products. The cost of generic acetazolamide was 37% less than brand-name acetazolamide, when available. Food intake did not appear to influence the absorption of acetazolamide.
D000086:Acetazolamide / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D001682:Biological Availability; D003365:Costs and Cost Analysis; D004305:Dose-Response Relationship, Drug; D005502:Food; D005901:Glaucoma / Q000097:blood / Q000188:drug therapy; D006801:Humans; D013810:Therapeutic Equivalency
D000086:Acetazolamide