[Reorganization of the synapsoarchitectonics of the rat red nucleus after destruction of the motor cortex of the cerebral hemispheres].
In 50 white rats the red nucleus synaptic organization both normal and at various time (1, 2, 3, 5, 7, 10, 14, 21, 30 and 60 days) after destruction of the cerebral cortical motor area has been studied electron microscopically. Peculiarities of the synaptic organization in the parvicellular and macrocellular parts of the red nucleus and reorganization of the synapsoarchitectonics are demonstrated after the motor cortex has been destroyed. During the first 2-3 weeks after the destruction, certain degenerative changes are mainly noted in the parvicellular area of the red nucleus. Small axonal terminals with round light synaptic vesicles are subjected to degeneration according to the dark type, they form asymmetric synapses on small, sometimes--on middle dentritic branches. On the 21-30th day, together with the degenerative changes, plastic reorganization of the red nucleus synapsoarchitectonics both in the parvicellular area and in the macrocellular areas adjoining the latter are noted. Evidently, this reorganization takes place at the expense of the cerebello-rubral fibres. The participation of the inter-posito-rubral fibres terminating in the macrocellular part of the red nucleus is definitely stated. Their large terminals form synapses on the soma and the proximal dendrites of the giant and large neurons. It is from these axonal terminals that the growth cones take their origin on the 21st day after the destruction of the motor cortex. Later (on the 30th and the 60th day) new processes and synapses appear in the parvicellular part of the red nucleus. Some dendrites undergo certain changes. Dendro-dendritic synapses and complex synaptic contacts appear.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000293:injuries*; D009410:Nerve Degeneration; D051381:Rats; D012012:Red Nucleus / Q000648:ultrastructure*; D013569:Synapses / Q000648:ultrastructure*
Reorganizatsiia sinapsoarkhitektoniki krasnogo iadra krys posle razrusheniia motornogo polia kory polushariĭ bol'shogo mozga.