Reduction of Brucella species and Francisella tularensis cross-reacting agglutinins by dithiothreitol.
Cross-reaction agglutinin titers to Brucella abortus antigen were found in 42 of 128 tularemia serum specimens, and cross-reaction titers to Francisella tularensis antigen were found in 8 of 34 brucellosis serum specimens. The cross-reaction titers were reduced to 10 or less by dithiothreitol, suggesting that the titers are due to immunoglobulin M antibody.
D000373:Agglutinins / Q000032:analysis*; D002002:Brucella / Q000276:immunology*; D003429:Cross Reactions; D004229:Dithiothreitol / Q000494:pharmacology*; D005604:Francisella tularensis / Q000276:immunology*
D000373:Agglutinins; D004229:Dithiothreitol