Multiple sclerosis and diabetes mellitus: further evidence of a relationship.
One hundred multiple sclerosis (MS) patients were compared to healthy controls to determine the prevalence of diabetes mellitus in their families. Significantly, more MS patients than controls were diabetic or reported at least one first degree relative (parent, sibling, child) with diabetes. The relationship between MS and diabetes persisted when second degree relatives (grandparents, aunts and uncles) were taken into consideration. A greater percentage of MS patients with another MS relative were diabetic or reported a first degree relative with diabetes mellitus than MS patients without an MS relative. However the difference was not statistically significant. Nor was there a significant difference when percentages reporting either a first or a second degree relative with diabetes were compared.
D000328:Adult; D000367:Age Factors; D003920:Diabetes Mellitus / Q000235:genetics* / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics; D003929:Diabetic Neuropathies / Q000209:etiology; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000235:genetics* / Q000378:metabolism; D012737:Sex Factors; D012959:Socioeconomic Factors