title: A novel method for the rapid bleeding of rats from the tail vein.
abstract: A method for bleeding rats from the tail vein was developed. Sufficient vasodilation of the tail was accomplished by the use of a specially designed warming device. With the help of a physical restrainer, up to 5 ml of blood can be collected from the tail vein and no anaesthesia is required. This bleeding procedure is fast, simple to perform, and imposes practically no risk to the animal.
mesh_terms: D000818:Animals; D001815:Bloodletting / Q000295:instrumentation; D006358:Hot Temperature; D008722:Methods; D051381:Rats; D012149:Restraint, Physical; D013623:Tail / Q000098:blood supply*; D014680:Veins