Fatal hepatitis following irradiation and vincristine.
The increasing use of combination therapy with irradiation and cytostatics in malignant disease increases the risk of toxicity. An account is given of a patient with liver toxicity terminating fatally, in whom increased radiosensitivity may have been induced by vincristine.
D000328:Adult; D005260:Female; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000528:radiation effects; D008223:Lymphoma / Q000532:radiotherapy; D011838:Radiation-Sensitizing Agents; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D014750:Vincristine / Q000009:adverse effects*
D011838:Radiation-Sensitizing Agents; D014750:Vincristine