title: Midazolam, a water-soluble benzodiazepine, for gastroscopy.
abstract: Midazolam, a water-soluble benzodiazepine, was given intravenously in doses of 0.07 mg/kg as sedation prior to oesophago-gastro-duodenoscopy in 40 patients. This was very effective as a sedative in elderly patients but less so in the young, with a large individual variation in response. Pain on injection and venous thrombosis which are common with diazepam were not seen with midazolam.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D001285:Atropine / Q000494:pharmacology; D001569:Benzodiazepines / Q000008:administration & dosage; D005773:Gastroscopy; D006801:Humans; D006993:Hypnotics and Sedatives; D007275:Injections, Intravenous; D008874:Midazolam; D008875:Middle Aged; D011292:Premedication
chemical_list: D006993:Hypnotics and Sedatives; D001569:Benzodiazepines; D001285:Atropine; D008874:Midazolam