Tetramethyl substitution on succinonitrile confers pentylenetetrazol-like activity and blocks cyanide release in mice.
D000818:Animals; D001921:Brain / Q000187:drug effects; D003292:Convulsants; D003486:Cyanides / Q000097:blood*; D000431:Ethanol / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D051379:Mice; D009570:Nitriles / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000633:toxicity*; D013329:Structure-Activity Relationship; D013861:Thiocyanates / Q000097:blood
D003292:Convulsants; D003486:Cyanides; D009570:Nitriles; D013861:Thiocyanates; C036591:tetramethylsuccinonitrile; C010337:succinonitrile; D000431:Ethanol