[Radioimmunological determination of the serum level of folic acid in healthy persons and patients treated by periodic hemodialysis].
Folic acid serum level was assayed in 31 patients with chronic renal insufficiency, hemodialysis-treated. Decreased level was established in 9 patients (30%). The average value of serum folic acid was 5.24 ng/ml (11.8 nmol/l) with a norm of 5.79 ng/ml (13.1 nmol/l) in the control group. No statistically significant difference was found between the healthy subjects and the patients. A low correlation dependence was found between serum folic acid level and the duration of hemodialysis treatment and diuresis. No statistically significant difference was established in the value of the folic acid in the patients on dialysis two or three times weekly. The irrational nutrition was concluded by the authors, to play a more significant role in the present disturbed folic homeostasis than the hemodialysis treatment per se.
D004231:Diuresis; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D005492:Folic Acid / Q000097:blood*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D008297:Male; D011863:Radioimmunoassay; D012016:Reference Values; D006435:Renal Dialysis; D013997:Time Factors
D005492:Folic Acid
Radioimunologichno opredeliane na serumnoto nivo na folievata kiselina pri zdravi litsa i bolni, lekuvani s periodichna khemodializa.