title: [Prognosis and clinical course in patients with advanced, inoperable coronary heart disease].
abstract: The clinical course, factors of prognostic significance and the quality of life in 128 patients with coronary heart disease rejected for revascularization surgery between 1970 and 1981 and followed up for 1-135 months (mean 43 months) were evaluated. The reason for rejection for bypass surgery was poor left ventricular function in 15 patients, diffusely diseased coronaries in 82 patients and both of the above in 31 patients. The actuarial 5-year survival rate in the entire population amounted to 53%, resulting in an average annual mortality rate of 9.4%. Left ventricular ejection fraction and end-diastolic pressure at rest were the only parameters of prognostic significance. Neither age, history of myocardial infarction, physical working capacity nor the number of diseased vessels were of prognostic value. Despite having "inoperable" coronary artery disease, many patients were able to continue gainful employment (61%) and were not severely restricted by angina (50% NYHC I-II).
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000209:etiology; D003327:Coronary Disease / Q000150:complications / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013557:Switzerland
vernacular_title: Prognose und Verlauf bei Patienten mit fortgeschrittener, inoperabler koronarer Herzkrankheit.