title: Histology of the stroma in developing rat subcutaneous adipose tissue.
abstract: Microscopic changes in the stroma of developing adipose tissues were studied. An organized arrangement of collagen fibers was associated with spindle-shaped cells with basophilic cytoplasm. An unorganized arrangement of collagen fibers was associated with cells of irregular shape, little cytoplasmic basophilia and a large pale-staining nucleus. Adipocyte development was apparent only in unorganized collagen fibers. The unorganized stroma was located near muscle-tendon junctions. Other aspects of muscle were surrounded by organized stroma. Physical interactions between expanding muscle and connective tissue cells may prevent or delay collagen maturation, resulting in a matrix suitable for adipocyte development.
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology* / Q000648:ultrastructure; D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D003094:Collagen; D009132:Muscles / Q000033:anatomy & histology; D051381:Rats / Q000033:anatomy & histology*; D011919:Rats, Inbred Strains / Q000033:anatomy & histology
chemical_list: D003094:Collagen