title: [Action of UV radiation on the surface of mammalian immunocompetent cells. I. Changes in the antigen and surface receptor expression of mouse spleen lymphocytes].
abstract: Non-lethal and small lethal doses of short-wave (254 nm) and long-wave UV light (365 nm), the SUV and LUV rays, when acting upon the murine spleen cells, induce an increase in expression of the membrane markers of T-lymphocytes [theta-(Thy-I)-antigens] and B-lymphocytes (MBLA-antigens and EAC receptors). The sum of cells with T- and B-lymphocyte markers in an irradiated suspension is even more than the total amount of cells in a non-irradiated suspension (100%), which indicates the possibility of expression of those antigens and receptors of the plasmic membrane which are not revealed in non-irradiated lymphocytes. In the range of isolethal dosages (LD15-LD28) LUV irradiation suppresses, while that of SUV induces further increase of the expression of theta- and MBLA-antigens. From among the membrane markers of B-lymphocytes, the MBLA-antigens are more resistant against LUV and SUV irradiation than EAC-receptors.
mesh_terms: D000818:Animals; D000954:Antigens, Surface / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D008214:Lymphocytes / Q000276:immunology / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D011971:Receptors, Immunologic / Q000528:radiation effects*; D012397:Rosette Formation; D013154:Spleen / Q000276:immunology*; D014466:Ultraviolet Rays
chemical_list: D000954:Antigens, Surface; D011971:Receptors, Immunologic
vernacular_title: Deĭstvie UF izlucheniia na poverkhnost' immunokompetentnykh kletok mlekopitaiushchikh. I. Izmenenie ékspressii nekotorykh antigenov i retseptorov poverkhnosti limfotsitov selezenki myshi.