Catalytic role of some phenolic substances in endogenous formation of N-nitroso compounds.
N-nitrosation can be catalysed or inhibited in vivo by different naturally-occurring polyphenolic compounds. The catalytic effect is particularly affected by pH. Thus, individual dietary habits can be expected to have marked effects on endogenous formation of N-nitroso compounds because of catalysis by polyphenols in foodstuffs, in addition to individual differences in pH.
D000818:Animals; D002384:Catalysis; D005247:Feeding Behavior; D006863:Hydrogen-Ion Concentration; D009603:Nitroso Compounds / Q000378:metabolism*; D010636:Phenols / Q000494:pharmacology*; D051381:Rats
D009603:Nitroso Compounds; D010636:Phenols