title: [Adaptative effect of methyltestosterone on the protective behavior of male rats].
abstract: It was shown that male rats castrated one month before the experiment, were not able to pass into a dark cage from a light one, if the excitation, produced by the electrode floor between dark and light parts, was slightly higher than that of the pain threshold. Neither affiliation nor sexual desire change their passing ability. Methyltestosterone injections in doses of 25 mg/kg intraperitoneally 30 minutes before castration markedly enhance the capacity of the same male rats to realize the passage into a dark cage, owing to an almost double fall of the pain threshold and increased pain tolerance. Methyltestosterone affiliation and sexual desire stimulate the pain barrier overcoming at the moment of passing into a dark cage. Methyltestosterone analgesic activity was found to be 5 times more powerful when studied in the cage, allowing the passage into a dark cage, in contrast to the similar test performed under a bell glass. The results obtained illustrate an adaptive methyltestosterone role in the form studied in non-sexual specific protective behaviour.
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002369:Castration; D005260:Female; D008297:Male; D008777:Methyltestosterone / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology; D051381:Rats; D012684:Sensory Thresholds / Q000187:drug effects; D012726:Sexual Behavior, Animal / Q000187:drug effects
chemical_list: D008777:Methyltestosterone
vernacular_title: Adaptivnoe vliianie metiltestosterona na zashchitnoe povedenie samtsov krys.