A comparison of coulometric detectors for catecholamine analysis by LC-EC.
An ion-pairing chromatographic method which uses a controlled potential coulometric detector is described. Two coulometric detectors with different electrolytic cell designs have been investigated. The resulting sensitivity can be comparable to the conventional amperometric detector. This technique has been applied to the analysis of catecholamines.
D002395:Catecholamines / Q000032:analysis*; D004298:Dopamine / Q000031:analogs & derivatives / Q000032:analysis; D004563:Electrochemistry / Q000295:instrumentation*; D004566:Electrodes; D004572:Electrolysis; D004837:Epinephrine / Q000032:analysis / Q000097:blood; D006801:Humans; D009638:Norepinephrine / Q000032:analysis / Q000097:blood
D002395:Catecholamines; C022133:3,4-dihydroxybenzylamine; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine