Failure of phorbol myristate acetate to damage DNA in leukocytes from patients with chronic granulomatous disease.
Unlike leukocytes from normal donors, leukocytes from patients with chronic granulomatous disease do not suffer DNA damage on exposure to the tumor promoter, phorbol myristate acetate.
D004247:DNA; D006105:Granulomatous Disease, Chronic / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000187:drug effects* / Q000378:metabolism; D010704:Phorbols / Q000494:pharmacology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*
D010704:Phorbols; D004247:DNA; D013755:Tetradecanoylphorbol Acetate