[Comparative immunologic studies in PUVA and SUP (selected ultraviolet phototherapy) treatments].
10 PUVA and 13 SUP-treated psoriatic patients were examined immunologically. The proportion of sheep and mouse erythrocyte rosette forming lymphocytes, the leucocyte migration inhibitory assay, the lymphocyte transformation test were carried out and the suppressor function of peripheral blood mononuclear cells was measured before and 48 hours after the clearing of lesions. The results observed before and after the treatment were compared to each other and to the values of healthy volunteers. No significant difference was observed between the results obtained before and after the treatment, meaning that the immune alterations, which have been observed by several authors immediately after PUVA therapy or UV light irradiation, were not detectable if the tests wer made 48 hours later than the last treatment. The significantly decreased suppressor function of peripheral blood mononuclear cells was not changed during the therapy either.
D002464:Cell Migration Inhibition; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D011701:PUVA Therapy / Q000379:methods; D010778:Photochemotherapy / Q000379:methods; D011565:Psoriasis / Q000188:drug therapy* / Q000276:immunology; D012397:Rosette Formation
Vergleichende immunologische Untersuchungen bei PUVA- und SUP-Behandlungen.