title: Structure, energetics and dynamics of ligand binding to dihydrofolate reductase.
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003201:Computers; D008727:Methotrexate / Q000378:metabolism*; D011485:Protein Binding; D011487:Protein Conformation; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism*; D013816:Thermodynamics
chemical_list: D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate