Enhanced saliva-mediated bacterial aggregation and decreased bacterial adhesion in caries-resistant versus caries-susceptible individuals.
A study of saliva-mediated aggregation and adhesion has been carried out in a group of caries-resistant (CR) and caries-susceptible (CS) individuals. The submandibular saliva of the CS group had a much greater potency, as determined by dilution, in promoting adherence to hydroxyapatite beads than did the saliva of CR group. In contrast, the CR group demonstrated a twofold enhancement of saliva-mediated aggregation compared with the CS group. These observations support the hypothesis that saliva-mediated aggregation and adherence are important factors in caries resistance.
D000268:Adhesiveness; D000328:Adult; D000368:Aged; D003731:Dental Caries / Q000276:immunology*; D004198:Disease Susceptibility; D006801:Humans; D006882:Hydroxyapatites; D007113:Immunity, Innate; D008875:Middle Aged; D012463:Saliva / Q000502:physiology*; D013295:Streptococcus mutans / Q000502:physiology*; D013298:Streptococcus sanguis / Q000502:physiology*
D006882:Hydroxyapatites