[Liver lysosome enzyme in rat ontogeny].
The dynamics of changes in the activity of 8 lysosomal hydrolases (acid DNAse, RNAse, phosphatase, arylsulphatases A and B, catepsins A, B1, C and D) was studied in the liver of rats from the 16th day of development till the 720th day of life. The marked activity of acid DNAse, RNAse, phosphatase and catepsins A, B1 and D was found already during the embryonic period. For the most hydrolases under study the peak of activity during the early postnatal life was established (10th day of life) which exceeded 5-7 times the level characteristic for the adult animals. The role of lysosomes in the reaction of biochemical adaptation of the organism to the changes of environmental conditions during ontogenesis is discussed.
D000375:Aging; D000818:Animals; D005260:Female; D005865:Gestational Age; D006867:Hydrolases / Q000378:metabolism*; D008099:Liver / Q000196:embryology / Q000201:enzymology* / Q000254:growth & development; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D006867:Hydrolases
Fermenty lizosom pecheni v ontogeneze krys.