title: Thymidine triphosphate dephosphorylating activity in regenerating rat liver.
abstract: The enzyme activity of dephosphorylation of thymidine triphosphate was found in microsomal fraction of rat liver. The enzyme activity decreased at the time when [3H]thymidine incorporation into DNA of regenerating liver increased. When the [3H]thymidine incorporation was suppressed by 1,3-diaminopropane, the enzyme activity remained elevated. These results suggest that the enzyme activity appears to be closely linked to DNA synthesis.
mesh_terms: D000818:Animals; D003600:Cytosol / Q000201:enzymology; D004261:DNA Replication; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D008930:Mitochondria, Liver / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D013942:Thymine Nucleotides / Q000378:metabolism*
chemical_list: D013942:Thymine Nucleotides; C024157:thymidine 5'-triphosphate