title: Electrophoresis of CSF proteins.
abstract: In this review we have tried to indicate the potential importance and interest of the proteins of the CSF and have argued that only by electrophoresis can these be examined in context. Without the need for expensive or elaborate equipment, a small volume of CSF can be used to demonstrate the pattern of proteins present, various qualitative changes, and the amounts of some individual proteins. For routine work this is of practical help in the diagnosis of certain neurological conditions, and as a research tool it can be utilized to investigate changes in protein structure and function occurring as part of immune or other responses. Access to neural tissue is necessarily restricted, but there is a great deal to be learned from the CSF.
mesh_terms: D001812:Blood-Brain Barrier; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D003937:Diagnosis, Differential; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods*; D004660:Encephalitis / Q000134:cerebrospinal fluid; D006801:Humans; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D008180:Lupus Erythematosus, Systemic / Q000134:cerebrospinal fluid; D008581:Meningitis / Q000134:cerebrospinal fluid; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid; D009494:Neurosyphilis / Q000134:cerebrospinal fluid; D011115:Polyneuropathies / Q000134:cerebrospinal fluid; D012507:Sarcoidosis / Q000134:cerebrospinal fluid; D013344:Subacute Sclerosing Panencephalitis / Q000134:cerebrospinal fluid
chemical_list: D002556:Cerebrospinal Fluid Proteins; D007136:Immunoglobulins