title: Results of single-dose treatment of vaginal mycoses with 500 mg Canesten vaginal tablets.
abstract: 212 patients with cultural evidence of yeast-induced vaginal mycosis were treated with a single vaginal tablet of 500 mg clotrimazole. A diagnosis of infection due to a Candida species had been established before therapy in 95% of the patients studied. From the total group of 212 patients a further group was formed who had appeared at the check-ups as scheduled in the trial protocol and whose data were complete. This group included 83 cases. There was no therapeutic difference between the two patient groups. 89% of the patients of the total patient group evaluable were found to be mycologically cured at both check-ups. In the reduced patient group the rates of mycological cure at the times of examination were 87 and 89%, respectively. The clinical results obtained in the total patient group indicated a therapeutic success of 90% at both check-ups. In the reduced patient group the rate of therapeutic success was 93% at the first and 88% at the second check-up. The local tolerability of the Canesten vaginal tablet was good. The side effects observed were rare and mild.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003022:Clotrimazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy*; D013607:Tablets; D013997:Time Factors; D014623:Vaginal Diseases / Q000188:drug therapy*
chemical_list: D007093:Imidazoles; D013607:Tablets; D003022:Clotrimazole