Effects of inhibitors of passive Na+ and HCO3- fluxes on electrical potential and fluid transport across rabbit corneal endothelium.
We found that amiloride and SITS, which are inhibitors of passive movements of Na+ and HCO3- across cell membranes, inhibited but did not abolish the electrical potential difference and net fluid transport across the rabbit corneal endothelium.
D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / Q000494:pharmacology*; D000200:Action Potentials / Q000187:drug effects; D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D001693:Biological Transport, Active / Q000187:drug effects; D003315:Cornea / Q000187:drug effects* / Q000378:metabolism; D004727:Endothelium / Q000187:drug effects; D066298:In Vitro Techniques; D011719:Pyrazines / Q000494:pharmacology*; D011817:Rabbits; D012964:Sodium / Q000378:metabolism; D013267:Stilbenes / Q000494:pharmacology*
D001639:Bicarbonates; D011719:Pyrazines; D013267:Stilbenes; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; D000584:Amiloride; D012964:Sodium