[Chronic hypernatremia. A study of plasma neurophysins and action of morphine].
The hypothalamo-neurohypophyseal function was evaluated in a patient with the chronic hypernatremia syndrome. By dosing plasmatic neurophysins, a selective loss of the osmoreceptor function was demonstrated. Morphine administration was followed by a reduction of the diuresis and a slight elevation of plasmatic neurophysins. The mechanism of morphine action is discussed.
D002908:Chronic Disease; D006801:Humans; D006955:Hypernatremia / Q000097:blood / Q000503:physiopathology*; D009020:Morphine / Q000494:pharmacology*; D009481:Neurophysins / Q000097:blood*
D009481:Neurophysins; D009020:Morphine
Hypernatrémie chronique. Etude des neurophysines plasmatiques et effet de la morphine.