Secondary alpha-hydrogen isotope effects on the interaction of 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase.
D003856:Deoxyuracil Nucleotides / Q000378:metabolism*; D005468:Fluorodeoxyuridylate / Q000378:metabolism*; D006859:Hydrogen / Q000494:pharmacology*; D007700:Kinetics; D008780:Methyltransferases / Q000378:metabolism*; D013763:Tetrahydrofolates / Q000378:metabolism*; D013940:Thymidylate Synthase / Q000378:metabolism*
D003856:Deoxyuracil Nucleotides; D013763:Tetrahydrofolates; C013123:5,10-methylenetetrahydrofolic acid; D005468:Fluorodeoxyuridylate; D006859:Hydrogen; D008780:Methyltransferases; D013940:Thymidylate Synthase