Hb Belfast (beta 15 Trp replaced by Arg) in an Italian family.
An uncommon abnormal hemoglobin, Hb Belfast (beta 15 Trp replaced by Arg) was discovered in a patient of Italian origin. The patient was a 42-year-old man who developed two episodes of jaundice after a prolonged administration of an antituberculous drugs. Family studies revealed that several members were asymptomatic carriers of Hb Belfast.
D000328:Adult; D001120:Arginine; D055598:Chemical Phenomena; D002621:Chemistry; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006455:Hemoglobins, Abnormal / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007558:Italy; D008297:Male; D010375:Pedigree; D014364:Tryptophan
D006454:Hemoglobins; D006455:Hemoglobins, Abnormal; C036392:hemoglobin Belfast; D014364:Tryptophan; D001120:Arginine