Ichthyosis vulgaris palmaris et plantaris dominans: a peculiar form of ichthyosis vulgaris localized on the palms and soles.
4 cases with congenital hyperkeratotic lesions localized on the palms and soles, occurring in three generations of one family, were observed. The atrophic, hyperkeratotic lesions accompanied by anhidrosis were dirty yellowish-brown coloured, with an ill-defined border but without any erythematous or pigmented halo. Further clinical findings were conspicuous dryness, adherent scale formation, fissurings and parchment paper-like luster. Histological findings were identical to those of ichthyosis vulgaris, with an absence of eccrine sweat glands. Hence, this type of hyperkeratosis can be distinguished from other types of inherited palmoplantar keratosis. For this peculiar form of dominantly inherited palmoplantar keratosis, the author proposed the new name 'ichthyosis vulgaris palmaris et plantaris dominans'.
D000328:Adult; D002648:Child; D005260:Female; D005533:Foot Dermatoses / Q000235:genetics* / Q000473:pathology; D005799:Genes, Dominant; D006229:Hand Dermatoses / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007057:Ichthyosis / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012867:Skin / Q000473:pathology; D009626:Terminology as Topic