title: Neurophysiological mechanism of shrinkage of nasal mucosa induced by exercise.
abstract: Change of serum norepinephrine level and nasal patency were measured in 10 normal volunteers during exercise and effect of unilateral cervical sympathetic ganglion block on exercise-induced shrinkage of nasal mucosa was evaluated. Serum norepinephrine elevated markedly after 10-min exercise. Unilateral blocking of cervical ganglion completely inhibited mucosal shrinkage induced by exercise in 8 of 10 subjects. Mucosal shrinkage during exercise in these subjects was assumed to be mediated through cervical sympathetic ganglion, and not by increase in circulating cathecolamine. However, in 2 subjects, moderate shrinkage of the nasal mucosa was observed in 10-min after initiation of exercise. It was impossible to rule out some effect of circulating cathecolamine on the capacitance vessels of the nasal mucosa completely.
mesh_terms: D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D000818:Animals; D001340:Autonomic Nerve Block; D001794:Blood Pressure; D004285:Dogs; D005728:Ganglia, Sympathetic / Q000502:physiology; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000502:physiology*; D009638:Norepinephrine / Q000097:blood; D005082:Physical Exertion
chemical_list: D009638:Norepinephrine