Precise mapping of the gene for Ly-21.2 on the 7th chromosome.
We have recently described a murine lymphocyte alloantigen, Ly-21.2, and showed that the gene which controls Ly-21.2 expression is linked to albinism on the 7th chromosome. In order to map the gene more precisely, we have studied the linkage of Ly-21.2 with two other genetic markers on the 7th chromosome, the electrophoretic variant of the beta chain of haemoglobin and glucose phosphate isomerase, in (A/J x C57BL/10)F2 mice. The results of these 3-point cross studies show that the gene encoding Ly-21.2 maps 27 units distal to albinism.
D000417:Albinism / Q000235:genetics; D000818:Animals; D000950:Antigens, Ly / Q000235:genetics*; D002874:Chromosome Mapping; D005796:Genes; D008040:Genetic Linkage; D005956:Glucose-6-Phosphate Isomerase / Q000235:genetics; D006454:Hemoglobins / Q000235:genetics; D007519:Isoantigens; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*
D000950:Antigens, Ly; D006454:Hemoglobins; D007519:Isoantigens; D005956:Glucose-6-Phosphate Isomerase