[Reorganization patterns in the synaptic architectonics of the neocortex in the postresuscitation period].
Staining of brain tissue with phosphotungstic acid was used to assay interneuronal contacts in the molecular layer of the cerebral cortex of rats with a history of clinical death because of hemorrhage and asphyxia. Common regularities of reconstruction of neocortical architectonics during the resuscitation period were defined. Marked reduction in the number of synapses was discovered in the neocortex. The main form of destruction of the contacts was the light type of destruction. Hypertrophy of the remaining synapses occurs in the early periods. The processes of neosynaptogenesis get activated on day 7. Both the types of structural recovery of the synaptic pool (hypertrophy and neoformation of the contacts) were fairly marked in the long-term period.
D000818:Animals; D001237:Asphyxia / Q000473:pathology; D002540:Cerebral Cortex / Q000648:ultrastructure*; D006470:Hemorrhage / Q000473:pathology; D007395:Interneurons / Q000648:ultrastructure; D008854:Microscopy, Electron; D051381:Rats; D012151:Resuscitation; D013569:Synapses / Q000648:ultrastructure*; D013997:Time Factors
Zakonomernosti reorganizatsii sinapsoarkhitektoniki neokorteksa v postreanimatsionnom periode.