title: [Effect of naloxone on the exploratory activity of mice].
abstract: The authors after going carefully over the specific bibliography on the matter, report their results relating to exploratory behaviour in mice after administration of naloxone (0, 05 mg/Kg i.p.). Exploratory behaviour was evaluated using an automatic recording hole-board, that simultaneously registered the locomotor activity. At the utilized doses, naloxone produced a significant decrease of exploring activity and a significant increase of motility, in comparison with drug-naive subjects. At the end, some possible interpretations are proposed about obtained results.
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D005106:Exploratory Behavior / Q000187:drug effects*; D008297:Male; D051379:Mice; D009270:Naloxone / Q000494:pharmacology*
chemical_list: D009270:Naloxone
vernacular_title: Effetto del naloxone sull'attivita' esplorativa di topi.