title: Effect of linoleic acid on digitalis cardiotoxicity.
abstract: Adult male guinea pigs were anesthetized, catheterized and i.v. infused with either saline and then ouabain or with linoleic acid salt and then ouabain. The linoleic acid pretreatment produced a significant delay until the onset of digitalis induced cardiac arrhythmias.
mesh_terms: D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002301:Cardiac Glycosides / Q000633:toxicity*; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D008041:Linoleic Acids / Q000494:pharmacology*; D008297:Male; D010042:Ouabain / Q000633:toxicity
chemical_list: D002301:Cardiac Glycosides; D008041:Linoleic Acids; D010042:Ouabain