Genetics of immunodeficiency diseases.
Immunodeficiency syndromes in childhood are partly congenital and due to metabolic errors. A majority are inherited, and from this group examples are presented of autosomal-recessive, X-linked, and dominant transmission. Reliable carrier identification and prenatal diagnosis are possible in a minority of these diseases, but clinical immunologists hope that new techniques will soon offer these possibilities to all families with hereditary forms of IDS.
D002648:Child; D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D006580:Genetic Carrier Screening; D008040:Genetic Linkage; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012729:Sex Chromosome Aberrations; D014960:X Chromosome