title: Advanced carcinoma of the cervix treated by continuous pelvic arterial infusion with cytostatics and radiation therapy.
abstract: Regional chemotherapy by infusion of cytostatic drugs (methotrexate and adriamycin) into the hypogastric arteries has been used in 25 cases of advanced carcinoma of the cervix (IIIB and IV stage). A method for the percutaneous introduction of catheters into these arteries and their permanence for a period of time of 8-12 days is described. After chemotherapy there was such a satisfactory reduction in size of the tumour that patients could then be treated with radiotherapy and/or surgery.
mesh_terms: D004317:Doxorubicin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008727:Methotrexate / Q000008:administration & dosage*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy
chemical_list: D004317:Doxorubicin; D008727:Methotrexate