The role of carbohydrate and protein level in the regulation of lipogenesis by the turkey poult.
Three and 8-week feeding trials were conducted with Large White turkey poults to determine the role of dietary protein and carbohydrate levels on in vitro lipogenesis. In vitro lipogenesis was measured as nanomoles of sodium acetate incorporated into fatty acids per 100 mg of liver. A 23% protein-51% carbohydrate energy diet was selected as a lipogenic diet. Antilipogenic diets were formulated by adding fat at the expense of carbohydrate while the protein level (23%) was held constant. Antilipogenic diets were also formulated by holding the carbohydrate energy level at approximately 45% and increasing the protein level. When the carbohydrate energy level was held between 45 and 51% of the total energy content, increasing the protein level was held constant, decreasing carbohydrate energy decreased (P less than .05) in vitro lipogenesis. Dietary reversals were also conducted with 3 and 8-week-old poults. Poults consumed either the lipogenic diet (23% protein-51% carbohydrate energy) or the antilipogenic diets (24% protein-33% carbohydrate energy) for 3 and 8 weeks. At the end of each period, poults were switched for 3-day periods from lipogenic to antilipogenic diets and vice versa. At both age periods, the switch from lipogenic to antilipogenic diets decreased (P less than .05) lipogenesis whereas the opposite switch increased (P less than .05) lipogenesis. Diets containing 33% carbohydrate energy were more effective repressors of lipogenesis after 3 days than was the 30% protein-45% carbohydrate energy diet.
D000818:Animals; D001835:Body Weight; D004032:Diet; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D005227:Fatty Acids / Q000096:biosynthesis; D005260:Female; D066298:In Vitro Techniques; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism; D008297:Male; D014422:Turkeys / Q000378:metabolism*
D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D005227:Fatty Acids; D008055:Lipids