[Blood supply and oxygen consumption in cat musculus gastrocnemius during isometric tetanus and intra-arterial infusion of norepinephrine].
In anesthetized cats with maximal isometric tetanus induced by the n. ischiadicus stimulation, the initial oxygen consumption depended on the 2--fold reduction of initial blood flow, the anaerobic metabolism index remaining the same, at that. Stimulation of the nerve induces practically the same mechanical activity of the muscle in control and after i. a. administration of noradrenaline, but the working hyperemia with concomitant changes of the metabolism indices becomes weaker than in control. A correlation of muscle blood supply changes with oxygen consumption changes was revealed whereas there was no correlation between changes of these indices and changes of oxygen extraction from the blood. A possibility of effects of the primary increase in blood flow occurring in hyperemia following the mechanical factor action, on the oxygen consumption is discussed as well as effect of willed decrease in blood flow within non-hypoxic range upon the oxidated metabolism.
D000818:Animals; D002415:Cats; D006940:Hyperemia / Q000378:metabolism; D007261:Infusions, Intra-Arterial; D007537:Isometric Contraction; D007773:Lactates / Q000097:blood; D009132:Muscles / Q000098:blood supply* / Q000378:metabolism; D009638:Norepinephrine / Q000502:physiology*; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D005082:Physical Exertion; D012039:Regional Blood Flow; D014680:Veins
D007773:Lactates; D010100:Oxygen; D009638:Norepinephrine
Krovosnabzhenie i potreblenie kisloroda ikronozhnoĭ myshtseĭ koshki pri izometricheskom tetanuse v usloviiakh vnutriarterial'noĭ infuzii noradrenalina.