[Resistance to the Venezuelan equine encephalomyelitis virus in immunization with live tularemia vaccine].
Guinea pigs immunized with live tularemia vaccine have been found to possess pronounced resistance to Venezuelan equine encephalomyelitis virus infection. Antiviral resistance induced by the vaccine has been found to persist for 1 month. One of the possible mechanisms, though not the only one, of this resistance is the stimulation of macrophages by tularemia vaccine, which results in the enhancement of their resistance to the cytotoxic action of the virus.
D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D004666:Encephalitis Virus, Venezuelan Equine / Q000276:immunology*; D005604:Francisella tularensis / Q000276:immunology*; D006168:Guinea Pigs; D007113:Immunity, Innate / Q000187:drug effects; D007114:Immunization; D008264:Macrophages / Q000276:immunology; D051379:Mice; D013997:Time Factors
D001428:Bacterial Vaccines
Rezistentnost' k virusu venesueél'skogo éntsefalomielita loshadeĭ pri immunizatsii zhivoĭ tuliaremiĭnoĭ vaktsinoĭ.