[Sodium azide--an activator of serum lipoproteins peroxidation].
Addition of even small amounts of sodium azide to preparations of blood serum lipoproteins of various classes, isolated by ultracentrifugation, intensified peroxidation of their lipids. At the same time, physical structure of blood serum lipoproteins was impaired as shown by activation of chemoluminescence using fluorescent probes pyrene and I-aniline naphthalene-8-sulphonate simultaneously with an increase in content of malonic dialdehyde. The data obtained suggest that the results of studies of protein-lipid structures in media containing azides have to be interpreted very carefully to avoid unwarranted conclusions.
D000818:Animals; D001386:Azides / Q000494:pharmacology*; D005456:Fluorescent Dyes; D006801:Humans; D066298:In Vitro Techniques; D008054:Lipid Peroxides / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D008079:Lipoproteins, VLDL / Q000097:blood*; D010084:Oxidation-Reduction; D011817:Rabbits; D019810:Sodium Azide
D001386:Azides; D005456:Fluorescent Dyes; D008054:Lipid Peroxides; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D019810:Sodium Azide
Azid natriia--aktivator perekisnogo okisleniia syvorotochnykh lipoproteidov.