Widespread marrow necrosis during pregnancy.
Recently, a 22-year-old Caucasian female was referred to our Hospital two days post-partum. She had been feeling unwell during the last few days of her pregnancy and complained of multiple aches and pains, worst in the abdomen and lower back. Her admission platelet count was severely depressed and a bone biopsy showed extensive marrow necrosis with viable bony trabeculae. There was no evidence of vasculitis, vascular thrombosis, or malignancy. Widespread marrow necrosis in pregnancy followed by recovery, to our knowledge, has not been previously reported.
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D001855:Bone Marrow Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010976:Platelet Count; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*