title: Dissolution of cystine calculi by pelviocaliceal irrigation with tromethamine-E.
abstract: We report 3 cases of cystine calculi. The stones were dissolved by pelviocaliceal irrigation with tromethamine-E, performed either through a percutaneous nephrostomy tube or ureteral catheters. The 25, 27 and 37-day courses of irrigation were well tolerated by all patients. Complications included a single asymptomatic urinary tract infection that required antibiotic therapy and transient hematuria due to catheter irritation. Our experience demonstrates that cystine calculi, including staghorn, can be dissolved by tromethamine-E irrigation, thereby obviating the need for surgical intervention.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003553:Cystine / Q000378:metabolism; D003555:Cystinuria / Q000150:complications; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D007507:Therapeutic Irrigation; D014325:Tromethamine / Q000627:therapeutic use*
chemical_list: D014325:Tromethamine; D003553:Cystine