Heinz-body haemolysis in haemodialysed patients caused by chloramines in Sydney tap water.
In August 1981, there was an outbreak of Heinz-body-positive haemolytic anaemia among patients who were undergoing dialysis in Sydney Hospital. This appeared to be due to excessive chloramines in and inadequate carbon filtration of, the water used for haemodialysis. After improvement of the carbon filtration system, there have been no further cases of anaemia.
D000743:Anemia, Hemolytic / Q000139:chemically induced* / Q000453:epidemiology; D001315:Australia; D002244:Carbon / Q000494:pharmacology; D002700:Chloramines / Q000009:adverse effects*; D003300:Copper / Q000032:analysis; D005374:Filtration; D006366:Heinz Bodies / Q000187:drug effects*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D009566:Nitrates / Q000032:analysis; D006435:Renal Dialysis / Q000009:adverse effects*; D014874:Water Pollutants, Chemical / Q000009:adverse effects; D014881:Water Supply / Q000592:standards
D002700:Chloramines; D009566:Nitrates; D014874:Water Pollutants, Chemical; D002244:Carbon; D003300:Copper