title: Two additional cases of coexisting polycythaemia vera and chronic lymphocytic leukaemia.
abstract: 2 patients with coexistent polycythaemia vera and chronic lymphocytic leukaemia are described. A 61-year-old man presented with an increased packed cell volume (PCV) and a leucoerythroblastic blood picture, which was reversible upon treatment, neutrophil leucoytosis, bone marrow lymphocyte infiltration and splenomegaly, and subsequently developed lymphomas, blood lymphocytosis and thrombocytosis. The second case was a 58-year-old female presenting with increased PCV and leucocyte alkaline phosphatase score. She later had neutrophil leucocytosis, thrombocytosis, lymphocytosis, lymphomas and splenomegaly. These cases, together with 6 cases published by others, suggest that an association exists between the two diseases.
mesh_terms: D004921:Erythropoietin / Q000096:biosynthesis; D005260:Female; D006400:Hematocrit; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D011087:Polycythemia Vera / Q000097:blood / Q000150:complications* / Q000175:diagnosis
chemical_list: D004921:Erythropoietin