[Contribution to importance of asbestos in the epidemiology of bronchial cancer].
Today asbestos is the most important professional carcinogenic agent of the respiratory tract. Asbestos caused bronchial cancer doesn't differ from its well-known morphology, progress and prognosis, but almost it is starting earlier. Fibrous form of asbestos represents its determinant potency. Carcinogenic fibres are about or below 1 micron in diameter and part of them can't be seen in light optical systems. Curious bodies may be missed sometimes also. A cancerogenic limit of asbestos concentration can't be quoted exactly now. Asbestos exposition during 60 contacting days or more are able to induce cancer. Cancerogenesis itself is during 20-30 years until clinical manifestation on an average. If the exposition is started in the youth, the period of latency is shortened distinctly. Tobacco smoke inhalations increase the carcinogenic effectiveness multiplicatively. In the districts of Magdeburg and Halle (GDR) more than 10% of the bronchial cancers are expected to be induced by asbestos. On the other hand only about 3% of the adults have had asbestos contacts at any former time. This is a raising of risk to at least triple rate.--It is necessary to realize all demands on technical prophylaxis of occupational asbestos exposition.
D000328:Adult; D000368:Aged; D001194:Asbestos / Q000009:adverse effects*; D002283:Carcinoma, Bronchogenic / Q000209:etiology*; D004781:Environmental Exposure; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology*; D008875:Middle Aged; D012306:Risk; D012907:Smoking; D013997:Time Factors
D001194:Asbestos
Beitrag zur Bedeutung des Asbestes für die Epidemiologie des Bronchialkarzinoms.