Treatment of Trichuris trichiura infection with a single dose of oxantel pamoate.
166 patients with trichuriasis have been treated at the Department of Tropical Diseases, Aurora Hospital, Helsinki, from January 1975 to October 1979. Final results could be confirmed in 141 patients. Thiabendazole was found discouraging, because of frequent side effects and low cure rate (29% of 24 in-patients). In contrast, a single dose of oxantel pamoate gave minimal side effects in 37 in-patients and in 80 outpatients with a high overall cure rate of 98%. Neither allergic nor adverse haematological reactions were encountered during 3 years and 10 months' experience of treatment with oxantel pamoate.
D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000008:administration & dosage; D000969:Antinematodal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011715:Pyrantel / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011716:Pyrantel Pamoate / Q000031:analogs & derivatives*; D013827:Thiabendazole / Q000627:therapeutic use; D014257:Trichuriasis / Q000188:drug therapy*
D000871:Anthelmintics; D000969:Antinematodal Agents; D011715:Pyrantel; D011716:Pyrantel Pamoate; D013827:Thiabendazole; C037225:oxantel pamoate