[Complement-binding capacity of aggregated immunoglobulins of different molecular weights].
The complement-fixing capacity of aggregated immunoglobulins with varying molecular weights has been explored. It has been demonstrated that as the molecular weight of a complex rises, the complement-fixing capacity increases. The amount of unfixed complement depends nonlinearly on the concentration of complement added and aggregated complexes in solution. The size of the complexes rather than their concentration plays the key role in the measurement of the complement-fixing capacity of aggregated immunoglobulins.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000378:metabolism; D001667:Binding, Competitive; D003165:Complement System Proteins / Q000378:metabolism*; D006168:Guinea Pigs; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007136:Immunoglobulins / Q000378:metabolism*; D008970:Molecular Weight
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D007136:Immunoglobulins; D003165:Complement System Proteins
Komplementsviazyvaiushchaia sposobnost' agregirovannykh immunoglobulinov razlichnykh molekuliarnykh mass.