title: Controlled tests of pastes of dichlorvos and thiabendazole against induced Strongyloides westeri infections in pony foals in 1973-1974.
abstract: In 1973-1974, 4 controlled tests were performed in pony foals (n = 17) raised parasite-free and experimentally infected with Strongyloides westeri. Administration of infective larvae by stomach tube in 1 test resulted in low-grade infections and tended to invalidate the test. Intraoral and percutaneous (intra-aural) administration of larvae resulted in suitable test infections for 1 and 2 tests, respectively. A paste formulation of dichlorvos at 36.3 mg/kg of body weight removal from 4 ponies. Treatment of 4 the dosage rate of 44 mg/kg was consistently effective (greater than 99% to 100%) for eliminating intestinal infections of S westeri.
mesh_terms: D000818:Animals; D004006:Dichlorvos / Q000008:administration & dosage / Q000627:therapeutic use*; D006736:Horses; D009824:Ointments; D013319:Strongyle Infections, Equine / Q000188:drug therapy*; D013827:Thiabendazole / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009824:Ointments; D004006:Dichlorvos; D013827:Thiabendazole