[Dibekacin: diffusion in bronchial mucus].
The study of the bronchial concentration of dibekacin has shown a different degree of activity than that of gentamicin. This activity resembles that of amikacin with a three hour time lag from the appearance of the bronchial peak in relationship to the serum peak. In addition there seems to be a special passage mechanism for the antibiotic from the blood into the bronchial secretions since we observed an increase in the mucus/serum ratio through time.
D000328:Adult; D000368:Aged; D001980:Bronchi / Q000378:metabolism*; D003982:Dibekacin / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007612:Kanamycin / Q000031:analogs & derivatives*; D007700:Kinetics; D008875:Middle Aged; D009093:Mucus / Q000378:metabolism*; D012141:Respiratory Tract Infections / Q000378:metabolism*
D003982:Dibekacin; D007612:Kanamycin
Dibékacine: diffusion dans le mucus bronchique.