title: Structure of bovine milk calcium phosphate determined by X-ray absorption spectroscopy.
abstract: Calcium in cow's milk is mainly in the form of calcium phosphate-phosphoprotein complexes known as casein micelles. These micelles, in contrast to other phosphoprotein complexes in bone and other tissues, can be readily isolated and studied, but conventional techniques have given ambiguous and conflicting evidence on the structure of milk calcium phosphate. Extended X-ray absorption fine structure and near-edge structure measurements at the newly commissioned Synchrotron Radiation Source at Daresbury indicate that it closely resembles brushite, CaHPO4 X 2H2O. This result, and chemical analysis, requires that phosphate groups from the matrix phosphoproteins be incorporated in the brushite lattice, probably in the surface, suggesting that these organic phosphate groups act as heterogeneous nucleation sites for phase separation of the calcium phosphate from solution.
mesh_terms: D000818:Animals; D002130:Calcium Phosphates / Q000032:analysis*; D002364:Caseins; D002417:Cattle; D003461:Crystallography; D005260:Female; D008823:Micelles; D008892:Milk / Q000032:analysis*; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D002130:Calcium Phosphates; D002364:Caseins; D008823:Micelles