Effects of estradiol on uptake of folate in isolated intestinal epithelial cells.
Estradiol 17 beta caused significant changes in the time course of 3H-folate uptake into isolated chick-intestinal epithelial cells. The radioactivity within the cells initially increased reaching a level of 1.5-2 times that of the control thereafter decreased to somewhat below the control levels. These changes were prevented by sodium azide but not by inhibitors of protein synthesis.
D000818:Animals; D002369:Castration; D002645:Chickens; D004848:Epithelium / Q000378:metabolism; D004958:Estradiol / Q000494:pharmacology*; D005492:Folic Acid / Q000378:metabolism*; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000187:drug effects; D014176:Protein Biosynthesis
D004958:Estradiol; D005492:Folic Acid