Change in auditory asymmetry with amobarbital: evidence of cerebral pharmacological asymmetry?
Eleven right-handed subjects were administered a dichotic listening test to assess cerebral hemispheric dominance, both under a drug-free condition and following systemic injection of the barbiturate, amobarbital. The finding of increased right ear advantage during the drug period reflects increased left cerebral dominance, and suggests that amobarbital may have an asymmetric, pharmacological effect on the two cerebral hemispheres.
D000328:Adult; D000654:Amobarbital / Q000494:pharmacology*; D001307:Auditory Perception / Q000187:drug effects*; D004292:Dominance, Cerebral / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D013067:Speech Perception / Q000187:drug effects
D000654:Amobarbital