The effect of ceruloplasmin on the multiplication and on some biological and physico-chemical characteristics of influenza virus A/PR8/34 (H0N1) cultivated on chorioallantoic membrane fragments. Note 1. Kinetics of virus multiplication and of some biological characteristics in the presence and absence of ceruloplasmin.
The presence of ceruloplasmin in the inoculum inhibits the multiplication of influenza virus A/PR8/34 (H0N1) in chorioallantoic membrane fragments. Virus corpuscles that remain uncoupled to ceruloplasmin infect the host cells and their replication results in progens whose properties differ from those of controls inoculated in the absence of ceruloplasmin. The variation in time of the characteristics of the respective virus progens is discussed.
D000482:Allantois / Q000382:microbiology; D000818:Animals; D002570:Ceruloplasmin / Q000494:pharmacology*; D002642:Chick Embryo; D002823:Chorion / Q000382:microbiology; D006389:Hemagglutinins, Viral / Q000032:analysis; D009980:Influenza A virus / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D007700:Kinetics; D009439:Neuraminidase / Q000032:analysis; D014764:Viral Proteins / Q000032:analysis; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects
D006389:Hemagglutinins, Viral; D014764:Viral Proteins; D002570:Ceruloplasmin; D009439:Neuraminidase