[Modulation of the functioning of muscarinic and nicotinic cholinoreceptors of dialyzed snail neurons by opiate peptides and morphine].
A modulating effect of morphine and enkephalins on the functioning of muscarinic and nicotinic cholinoreceptors of the snail neurons was studied by intracellular dialysis technique under voltage clamp conditions. It is found that different effects of these agents on acetylcholine responses of isolated neurons are due to their selective modulating influence on M- and N-cholinoreceptors.
D000109:Acetylcholine / Q000008:administration & dosage; D000818:Animals; D004347:Drug Interactions; D004743:Enkephalin, Leucine / Q000494:pharmacology; D004744:Enkephalin, Methionine / Q000494:pharmacology; D004745:Enkephalins / Q000494:pharmacology*; D006372:Helix, Snails; D066298:In Vitro Techniques; D009020:Morphine / Q000494:pharmacology*; D009474:Neurons / Q000187:drug effects; D011950:Receptors, Cholinergic / Q000187:drug effects*; D011976:Receptors, Muscarinic / Q000187:drug effects*; D011978:Receptors, Nicotinic / Q000187:drug effects*
D004745:Enkephalins; D011950:Receptors, Cholinergic; D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine; D009020:Morphine; D000109:Acetylcholine
Moduliatsiia funktsionirovaniia muskarinovykh i nikotinovykh kholinoretseptorow dializirovannykh neĭronov ulitki opiatnymi peptidami i morfinom.