Colposcopy, conization, and hysterectomy practices: a current perspective.
Data from the provincial cytology program has shown a progressive increase in the number of cases of cervical carcinoma in situ detected in the general population and a doubling of disease rate in third decade women, with most of the cases now in the 25- to 29-year-old age group. The introduction of a colposcopy service has led to a significant decrease in the number of diagnostic conizations performed over a 5-year period. Conization was still used for therapy in a substantial number of women despite the availability of cryotherapy and laser surgery. Eighty-five percent of all patients undergoing cone biopsy had sever dysplasia or carcinoma in situ (CIN III) on pathological examination. In 25% of patients, the conization specimen revealed either dysplasia or carcinoma in situ extending to resection margins. During review of 2249 patients, 1174 were spared a conization and were treated by either hysterectomy, cryotherapy, or laser surgery. It would appear that, although colposcopy can reduce dramatically the number of diagnostic cone biopsies, conization will still be required for therapy in a substantial number of patients.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001706:Biopsy; D001955:British Columbia; D002278:Carcinoma in Situ / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D002584:Cervix Uteri / Q000166:cytology / Q000473:pathology / Q000601:surgery*; D003127:Colposcopy; D003452:Cryosurgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D053685:Laser Therapy; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery