title: [Squamous cell carcinoma of the skin with bone involvement in hereditary dystrophic epidermolysis].
abstract: A report is given about a patient with a documented case history of hereditary dystrophic epidermiolysis over 43 years. The patient showed the rare malignant mutation resulting from chronic changes of the skin leading to a squamous cell carcinoma of the skin. The tibial bone under the affected skin area was attacked. The X-ray morphological findings of the osteolytic destruction of the tibia resulting in a pathological fracture and the changes in the skin, which are typical for the disease are discussed.
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D004820:Epidermolysis Bullosa / Q000150:complications*; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D012878:Skin Neoplasms / Q000209:etiology*; D013978:Tibial Fractures / Q000209:etiology
vernacular_title: Knochenbefall durch ein Plattenepithelkarzinom der Haut bei Epidermiolysis hereditaria dystrophica.