Golgi apparatus and acid phosphatase in mammary gland and kidney cells under the influence of diethylstilbestrol (DES).
It is commonly accepted that hormonal disturbances in experimental animals produce pathological changes in several organs namely in mammary glands and kidney. Taking into consideration the close relationship between acid phosphatase and Golgi apparatus, the present study was undertaken, to study the relationship in kidney and mammary gland cells under the influence of DES. The observation indicate, that acid phosphatase and Golgi apparatus were localized in the cytoplasm of mammary gland and kidney cells. It has also been found a parallel change in the activity of acid phosphatase and the degree of development of Golgi apparatus after DES administration.
D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D004054:Diethylstilbestrol / Q000494:pharmacology*; D005260:Female; D006056:Golgi Apparatus / Q000187:drug effects* / Q000648:ultrastructure; D007668:Kidney / Q000187:drug effects* / Q000201:enzymology / Q000648:ultrastructure; D008297:Male; D008321:Mammary Glands, Animal / Q000187:drug effects* / Q000201:enzymology / Q000648:ultrastructure; D051381:Rats
D004054:Diethylstilbestrol; D000135:Acid Phosphatase