title: [Hypothyroidism acquired in childhood. Apropos of case].
abstract: Authors present a patient who, when three years old, was studied because of weight and psychic retardation. Physical data were as following: weight, 9.9 Kg (less than 93); height, 90 cm (P 10-25); head circumference, 43,5 cm (less than P3); bone age, 2 3/12 years, and the thyroid function, normal. I131 uptake, 43.5% after 24 h. TBI: T3 index, 1.07; T4, 7.7 gamma %. FT4 index, 7.2. Thyroid scan, normal. Diagnosis was: intrauterine dwarfism and iron-deficiency anemia. At 6 6/12 years old, he had measles and at this time his mother noted rapid weight gain, decrease in the grow rate, besides a coarse, cold skin and constipation, that did-not previously exist. Thyroid study showed typical primary hypothyroidism: I131 uptake, 14% after 24 h. TBI: T3 index, 1.2; T4, 1.2 micrograms/100. TSH in the test of TRH of 165 micro U/ml base and 245 maximum. Anti-thyroidal antibodies were negative. In view of the time coincidence, authors speculate that measles virus is perhaps the aetiologic agent of the hypothyroidism either directly or through an autoimmune reaction.
mesh_terms: D001835:Body Weight; D002675:Child, Preschool; D006130:Growth Disorders / Q000150:complications; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000209:etiology*; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D008457:Measles / Q000150:complications*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones
vernacular_title: Hipotiroidismo adquirido en la infancia. A propósito de una observación.