Juvenile rheumatoid arthritis with renal amyloidosis: a 23-year survival.
A 14-year-old girl with juvenile rheumatoid arthritis developed severe renal amyloidosis and presented with nephrosis and renal failure. Renal function returned to normal in a year and over 23 years, serial biopsies showed remarkable, biopsy-proven regression of amyloid deposits. Amyloid was not found in skin, gum or rectal biopsies. This case demonstrates an improved prognosis and apparent reversibility.
D000293:Adolescent; D000686:Amyloidosis / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D001171:Arthritis, Juvenile / Q000150:complications*; D001706:Biopsy; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D013997:Time Factors