Concentration of dimethylnitrosamine in the air of smoke-filled rooms.
In order to evaluate the contribution of volatile nitrosamines from tobacco smoke to indoor air pollution, N-nitroso-dimethylamine (NDMA) and N-nitroso-diethylamine (NDEA) were measured in indoor air under artificial and natural conditions. In controlled experiments under extreme conditions, we found that tobacco smoke-related NDMA levels above 0.07 ng/liter were associated with a highly irritating atmosphere which was scarcely tolerable to those present. In smoke-filled rooms under natural conditions NDMA levels ranged from 0.02 to 0.05 ng/liter except a minimum value of less than 0.01 ng/liter in a restaurant and a maximum of 0.07 ng/liter in a dancing bar. These NDMA levels are thus below comparable values reported by others. The NDMA/NDEA ratios found in air samples taken from some rooms under conditions of everyday life are quite different from those found in sidestream smoke of cigarettes. Irritation was not reported under natural conditions. From the results it is concluded that NDMA levels, measured under real life conditions, are usually not caused by tobacco smoke alone. Evidence for other sources of volatile nitrosamines is discussed.
D000388:Air / Q000032:analysis*; D000393:Air Pollutants / Q000032:analysis*; D004128:Dimethylnitrosamine / Q000032:analysis*; D006801:Humans; D014028:Tobacco Smoke Pollution
D000393:Air Pollutants; D014028:Tobacco Smoke Pollution; D004128:Dimethylnitrosamine