[Metabolic studies under ergometric loading of patients with total duodenopancreatectomy].
One year after total duodenopancreatectomy a clinical and laboratory evaluation including exhaustive bicycle ergometry was performed in 6 male patients. The insufficiency of the exocrine pancreas can be compensated by at least 10 g pankreatin per day. During physical exercise patients had higher arterial values of lactate and free glycerol after duodenopancreatectomy than 7 healthy individuals and 6 diabetic patients type I. This metabolic overreaction was due to a deficiency of pancreatic glucagon and resulted in an impaired hepatic gluconeogenesis. There was no detectable increase in growth hormones and only a small one in catecholamines. The physical condition of patients after duodenopancreatectomy was clearly worse.
D000328:Adult; D003920:Diabetes Mellitus / Q000378:metabolism; D004386:Duodenum / Q000601:surgery*; D005080:Exercise Test; D010188:Exocrine Pancreatic Insufficiency / Q000378:metabolism*; D006801:Humans; D008297:Male; D010180:Pancreatectomy
Stoffwechseluntersuchungen unter ergometrischer Belastung bei total duodenopankreatektomierten Patienten.