Distribution of six TF C (transferrin) subtypes in cord bloods and blood donors.
Isoelectric focusing was used to subtype the common TF C phenotype into C1, C2 and C3, increasing the proportion of heterozygotes from virtually zero to 0.31. Five of the six subtypes of TF C were found in a series of 200 blood donors and 200 cord bloods. The frequencies of the three alleles were: TF*C1 = 0.80, TF*C2 = 0.17 and TF*C3 = 0.03 from cord bloods; and TF*C1 = 0.84, TF*C2 = 0.13 and TF*C3 = 0.03 from blood donors. These frequencies were comparable with estimates from other Caucasian populations. The average probability of detecting non-paternity for this population is increased to 11% by subtyping C into C1 and C2, and further increased to 15% by subtyping C into C1, C2 and C3.
D000483:Alleles; D001315:Australia; D001788:Blood Grouping and Crossmatching; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D005828:Genetics, Population; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010334:Paternity; D014168:Transferrin / Q000235:genetics* / Q000302:isolation & purification
D014168:Transferrin