Aging of the erythrocyte. XVII. Binding of autologous immunoglobulin G.
Increased amounts of autologous immunoglobulin (Ig) G were found on older bovine erythrocytes employing 125I-labelled Protein A, 125I-labelled anti(bovine IgG) antibodies and hemolysis in the presence of anti(bovine IgG) antibodies + complement. In vitro, desialylation, proteolysis and action of an O2-. source but not glycosylation induced binding of extraneous IgG to the erythrocytes.
D000818:Animals; D001323:Autoantibodies / Q000378:metabolism; D002417:Cattle; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000276:immunology; D006461:Hemolysis; D007074:Immunoglobulin G / Q000378:metabolism*; D011485:Protein Binding
D001323:Autoantibodies; D007074:Immunoglobulin G