[Mesangial lipidosis associated with cholesterol polycoria].
Accumulation of glomerular foam cells were seen in a kidney biopsy of a 59-years old patient with persistent proteinuria and mild renal insufficiency. Further investigations revealed hypercholesterolemia, hypertriglyceridemia, normal activity of LCAT, absence of lipoprotein x. Foam cells which were shown by histochemical methods to be loaded with intracytoplasmic cholesterol were found in bone marrow. These findings strongly suggest cholesterol-ester-storage disease with glomerular involvement.
D002784:Cholesterol / Q000378:metabolism*; D006801:Humans; D007674:Kidney Diseases / Q000378:metabolism* / Q000473:pathology; D007678:Kidney Glomerulus / Q000648:ultrastructure; D008064:Lipidoses / Q000150:complications*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged
D002784:Cholesterol
Lipidose mésangiale associée à une polycorie cholestérolique.