[Experimental chemotherapeutic activity of sisomycin sulfate].
The chemotherapeutic activity of sisomicin was studied in comparison to that of gentamicin with respect to the experimental infection caused by grampositive and gram-negative organisms in albino mice. It was shown that sisomicin was 2-3 times more effective than gentamicin. The higher chemotherapeutic activity of sisomicin was confirmed by the data on the pathogen isolation from the animals.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D005839:Gentamicins / Q000627:therapeutic use*; D051379:Mice; D008826:Microbial Sensitivity Tests; D011014:Pneumonia / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy; D012853:Sisomicin / Q000627:therapeutic use*
D005839:Gentamicins; D012853:Sisomicin
Khimioterapevticheskaia aktivnost' sizomitsina sul'fata v éksperimente.