Antagonism between nafcillin or oxacillin and rifampin against Staphylococcus aureus.
By the time-kill method, the combinations of nafcillin plus rifampin and oxacillin plus rifampin were antagonistic against 20 strains of Staphylococcus aureus. No synergism was demonstrated.
D004359:Drug Therapy, Combination; D008826:Microbial Sensitivity Tests; D009254:Nafcillin / Q000037:antagonists & inhibitors*; D010068:Oxacillin / Q000037:antagonists & inhibitors*; D012293:Rifampin / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects*
D009254:Nafcillin; D010068:Oxacillin; D012293:Rifampin