Congenital hemihypertrophy: oncogenic potential of the hypertrophic side.
Congenital hemihypertrophy is a rare condition, occasionally associated with neoplasms on the affected side of the body. Investigation of three cases disclosed increased growth rate of cultured skin keratinocytes and fibroblasts and high skin temperature on the hypertrophic side. These observations suggest the oncogenic potential of the affected side in the condition.
D000328:Adult; D001132:Arm / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D002528:Cerebellar Neoplasms / Q000209:etiology; D005147:Facial Bones / Q000473:pathology*; D005260:Female; D006130:Growth Disorders / Q000151:congenital*; D006394:Hemangiosarcoma / Q000209:etiology; D006801:Humans; D006984:Hypertrophy; D007866:Leg / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology*; D009506:Nevus / Q000209:etiology; D012878:Skin Neoplasms / Q000209:etiology