Canine parvovirus infections in a colony of dogs.
A serological study of canine parvovirus (CPV) infections in a colony of dogs was conducted over a period of 8 months. Twenty-two of 24 adults samples initially had significant antibody titres to CPV. Nine litters of puppies were bled at fortnightly intervals and the sera tested for antibodies to CPV. Twenty-nine of 35 naturally PV infections observed were subclinical. A puppy in one litter developed vomiting and diarrhoea during the same period as seroconversion to CPV. Four puppies from a further litter developed histologically confirmed myocarditis. Serological testing of this latter litter indicated that the virus infections occurred between 2 weeks prior to and 1 week post whelping, and that clinical disease developed 20-40 days after viral infection. The mean half life of the decline of passively derived immunity to CPV was 8.3 days.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D006385:Hemagglutination Inhibition Tests; D009205:Myocarditis / Q000209:etiology / Q000662:veterinary*; D010321:Parvoviridae / Q000276:immunology; D014777:Virus Diseases / Q000662:veterinary*
D000914:Antibodies, Viral