[Collodion baby and harlequin fetus. Comparison of 2 cases].
Two cases of severe congenital ichthyosis are presented: "collodion baby" and "harlequin fetus". The collodion baby is no clinical entity, but a symptom occurring in several forms of ichthyosis. In our patient the collodion skin was a symptom of ichthyosis congaenita (lamellar ichthyosis). Treatment with orally administered steroids was life-saving. The harlequin fetus represents a distinct entity characterized by a lethal genotype. There is a molecular defect of keratinization.
D005260:Female; D005315:Fetal Diseases / Q000473:pathology*; D006801:Humans; D007057:Ichthyosis / Q000188:drug therapy / Q000473:pathology*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy
D011241:Prednisone
Kollodiumbaby und Harlekinfetus.