[Occurrence of syphilis in blood donors in Dakar and the importance of the new serological detection methods, TPHA and GAST].
The authors examined 2230 blood donors serums with the passive Haemagglutination Test for Syphilis (TPHA) and compared it to routine serology (Kline and VDRL). They found a rather important percentage (10.9%) of positive TPHA in the blood donors of Dakar. As a specific and sensitive test, the TPHA keeps its whole interest in case of false positivity, principally in tropical countries. 142 blood donors serums were also examined with the GAST (Groupamatic Automated Syphilis Test). This test is easy to be done and can be applied to large numbers of serums. It seems more reproductible and specific than Kline and VDRL reactions.
D000328:Adult; D001782:Blood Donors; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D012675:Senegal; D013587:Syphilis / Q000453:epidemiology*; D013588:Syphilis Serodiagnosis
Incidence de la syphilis chez les donneurs de sang à Dakar et intérêt de nouvelles méthodes sérologiques de dépistage, TPHA et GAST.