[Radioimmunologic determination of circulating parathyroid hormone in patients with primary and secondary hyperparathyroidism].
A radioimmunological evaluation was made of plasma parathormone (PTH), using an antibody against the C-terminal fraction, in 14 subjects with primary parahyperthyroidism, and in 19 anuric subjects with secondary forms on three-weekly dialysis. In all cases, values were significantly higher (p less than 0.01) than in a group of normal controls. In secondary forms, the same significance was also apparent on comparison with primary forms, probably due to an absence of renal clearance of the hormone.
D000328:Adult; D000368:Aged; D000536:Aluminum Hydroxide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood*; D006962:Hyperparathyroidism, Secondary / Q000097:blood* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood*; D011863:Radioimmunoassay; D006435:Renal Dialysis
D010281:Parathyroid Hormone; D000536:Aluminum Hydroxide
Determinazione radioimmunologica del paratormone circolante in pazienti con iperparatiroidismo primitivo e secondario.