Decreased feeding associated with acute hypoxia in rats.
Rats obtained less food than normal on a cyclic-ratio schedule during brief, 1-hr exposure to either moderate hypobaric hypoxia (BP = 435 Torr, PO2 approximately equal to 91 Torr) or to hypoxic hypoxia (BP = 750 Torr, PO2, approximately equal to 90 Torr), but not during hypobaric exposure with 36.5% oxygen (BP = 435 Torr, PO2 approximately equal to 159 Torr). The depressed rate of feeding associated with hypoxia was nevertheless well regulated. Interpreted in terms of a regulatory model, these results suggest that hypoxia suppresses eating because it degrades the taste of food, not because it impairs feeding regulation or general activity.
D000531:Altitude; D000818:Animals; D001835:Body Weight; D003216:Conditioning, Operant / Q000502:physiology; D004435:Eating; D005260:Female; D000860:Hypoxia / Q000378:metabolism*; D008954:Models, Biological; D010100:Oxygen / Q000097:blood; D051381:Rats
D010100:Oxygen