title: [Experimental data on the toxicology of the esters of ethylcarbitol and fatty acids].
abstract: It was established in acute experiments on white rats and mice that the ester of ethylcarbitol and fatty acids is virtually not toxic. LD50 intragastrically is 36.5 g/kg for rats and 22.75 g/kg for mice. The threshold and subthreshold doses equal to 1.825 g/kg and 0.730 g/kg, respectively were determined in subacute experiments on rats. The ester of ethylcarbitol and fatty acids is a moderately cumulative substance.
mesh_terms: D000818:Animals; D001769:Blood / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004971:Estrus / Q000187:drug effects; D005026:Ethylene Glycols / Q000633:toxicity*; D005227:Fatty Acids / Q000633:toxicity*; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010053:Ovary / Q000187:drug effects; D011247:Pregnancy; D051381:Rats; D013091:Spermatogenesis / Q000187:drug effects; D013997:Time Factors
chemical_list: D005026:Ethylene Glycols; D005227:Fatty Acids
vernacular_title: Eksperimental'nye dannye o toksikologii éfira étilkarbitola i zhirnykh kislot.