title: In vitro migration of potential hemopoietic precursors from the murine fetus.
abstract: An in vitro migration system demonstrated the presence in murine fetal tissues of cells that migrate to thymus, spleen or lymph node. Preincubation of these cells with facteur thymique sérique, a factor derived from the thymus, produced changes in the migration patterns, suggesting a maturation sequence in fetal hemopoietic precursor-cell migration capacity, with migration to the thymus as the initial potential homing target, followed in order by a potential to migrate to the spleen, than to lymph-node tissue.
mesh_terms: D000818:Animals; D002465:Cell Movement; D005260:Female; D005333:Fetus / Q000166:cytology*; D008099:Liver / Q000196:embryology*; D008297:Male; D051379:Mice; D011247:Pregnancy; D013154:Spleen / Q000196:embryology; D013935:Thymic Factor, Circulating / Q000494:pharmacology*; D013950:Thymus Gland / Q000196:embryology; D013951:Thymus Hormones / Q000494:pharmacology*
chemical_list: D013951:Thymus Hormones; D013935:Thymic Factor, Circulating