Juvenile psoriatic arthritis--an analysis of 60 cases.
Sixty children who were considered to have juvenile psoriatic arthritis were analyzed retrospectively; the mean length of follow-up was 10.8 years. There was a female predominance of 3:2. The mean age at onset for both the psoriasis and the arthritis was between 8 and 9 years. A family history of psoriasis was present in almost half, and was a valuable clue in diagnosing the 26 of 60 who presented with arthritis first. The majority had a monarticular presentation, usually of the knee. Additional joints usually became involved sporadically in an asymmetric pattern, in both upper and lower limbs, so that 87% ultimately had polyarticular disease. This course is unlike the usual one of childhood arthritis. Although 40% were asymptomatic at follow-up, six patients required bilateral hip replacement, four within the first five years following the onset of arthritis. Sixteen patients received slow-acting drugs, usually gold; eight of these had had a polyarticular onset and seven a positive test for ANA.
D000367:Age Factors; D001171:Arthritis, Juvenile / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D002648:Child; D005260:Female; D005385:Fingers / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011379:Prognosis; D011565:Psoriasis / Q000150:complications* / Q000473:pathology / Q000628:therapy; D011859:Radiography; D012189:Retrospective Studies; D012446:Sacroiliac Joint / Q000000981:diagnostic imaging; D012737:Sex Factors; D014606:Uveitis, Anterior / Q000150:complications