title: [The amenorrhea-galactorrhea syndrome. Clinical and therapeutic aspects of 5 treated cases].
abstract: The behaviour of plasma prolactin in response to various pharmacological tests has been examined together with that of other hypophyseal function parameters in five patients suffering from amenorrhoea-galactorrhoea syndrome. Evaluation of plasma prolactin and hypophyseal tropinic reserve levels did not prove sufficient to discriminate between functional and organic forms of hyperprolactinaemia. A woman patient was submitted to neurosurgical operation for removal of a hypophyseal microadenoma. The other patients were treated medically with 2-alpha-bromoergocryptin which produced quick normalization of prolactinaemia with restoration of normal memstrual cycles and cessation of galactorrhoea.
mesh_terms: D000236:Adenoma / Q000150:complications / Q000601:surgery; D000328:Adult; D000568:Amenorrhea / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D001971:Bromocriptine / Q000627:therapeutic use*; D005260:Female; D005687:Galactorrhea / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D007775:Lactation Disorders / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*
chemical_list: D001971:Bromocriptine; D011388:Prolactin
vernacular_title: La sindrome amenorrea-galattorrea. Aspetti clinici e terapeutici in cinque casi osservati.