[Aneuploidia in malignant tumors of testis and their lymphatic metastases (author's transl)].
DNA-estimations, done by flow-through-cytophotometry, were performed in 18 malignant tumors of testis. Aneuploid stemlines which are specific for cancers were found in 17 cases. The only exception was a so called "occult seminoma". It showed only a small difference between the stem-line of tumor and normal cells of testis. So, by using DNA-estimation, it was possible to make a correct diagnosis all 18 patients, suffering from tumor of the testis. The aneuploid stem-lines of seminomas did not differ from those of other cancers. The type of proliferative behavior seems to be a criterion for prognosis. Lymphatic nodes with and without formation of metastases very clearly showed differences in the DNA-content of their nuclei.
D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000378:metabolism; D006801:Humans; D008207:Lymphatic Metastasis / Q000648:ultrastructure; D008297:Male; D013736:Testicular Neoplasms / Q000648:ultrastructure*
D004273:DNA, Neoplasm
Aneuploidie bei malignen Hodentumoren und ihren Lymphknotenmetastasen.