[Craniofacial amniogenic malformations within the Adam complex (author's transl)].
Four children are described with amniotic deformities in the craniofacial region. Besides encephaloceles, hydrocephalus, facial clefts, amniotic bands and furrows we observed in three of these children the deformities of the extremities which are characteristic of amniogenic malformations, such as syndactylias and mutilations, associated with ring constructions. The article describes the state of knowledge with regard to pathogenesis. Epidemiology of the disease permits to assume a very low risk of repeat occurrence with the parents concerned.
D000015:Abnormalities, Multiple / Q000196:embryology*; D000650:Amnion; D002675:Child, Preschool; D002971:Cleft Lip / Q000196:embryology; D002972:Cleft Palate / Q000196:embryology; D003394:Craniofacial Dysostosis / Q000196:embryology*; D004677:Encephalocele / Q000196:embryology; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D006849:Hydrocephalus / Q000196:embryology; D007223:Infant; D007231:Infant, Newborn; D017880:Limb Deformities, Congenital; D008297:Male; D008588:Meningocele / Q000196:embryology
Kraniofaziale, amniogene Fehlbildungen im Rahmen des ADAM-Komplexes.