title: Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22.
abstract: The segregation of the chromosome 22 markers ACO2, ARSA, and NAGA was studied in somatic cell hybrid clones. These hybrids were isolated following fusion of Chinese hamster (E36 or a3) cells with leucocytes of donors carrying an (X;22) or (1;22) translocation. The results suggest the assignment of ARSA and NAGA to the region 22q13 leads to 22qter and of ACO2 to the region 22q11 leads to 22q13.
mesh_terms: D000116:Acetylgalactosamine / Q000235:genetics; D000154:Aconitate Hydratase / Q000235:genetics*; D000818:Animals; D001192:Arylsulfatases / Q000235:genetics*; D002874:Chromosome Mapping; D002904:Chromosomes, Human, 21-22 and Y / Q000648:ultrastructure*; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D005796:Genes; D006596:Hexosaminidases / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure; D013429:Sulfatases / Q000235:genetics*; D014178:Translocation, Genetic; D014960:X Chromosome; D048809:alpha-N-Acetylgalactosaminidase
chemical_list: D013429:Sulfatases; D001192:Arylsulfatases; D006596:Hexosaminidases; C482722:NAGA protein, human; D048809:alpha-N-Acetylgalactosaminidase; D000154:Aconitate Hydratase; D000116:Acetylgalactosamine