Effect of SQ 80,338 (1-(3-phenyl-2-propenyl)-1H-imidazole) on thromboxane synthetase activity and arachidonic acid-induced platelet aggregation and bronchoconstriction.
D000818:Animals; D001095:Arachidonic Acids / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects / Q000201:enzymology*; D006168:Guinea Pigs; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008168:Lung / Q000187:drug effects / Q000502:physiology*; D008297:Male; D010088:Oxidoreductases / Q000378:metabolism*; D010974:Platelet Aggregation / Q000187:drug effects*; D012129:Respiratory Function Tests; D013930:Thromboxane-A Synthase / Q000378:metabolism*
D001095:Arachidonic Acids; D007093:Imidazoles; C025092:1-(3-phenyl-2-propenyl)-1H-imidazole; D010088:Oxidoreductases; D013930:Thromboxane-A Synthase