Preoperative treatment of hydatid cysts with mebendazole.
Mebendazole--an anthelmintic drug which is known to have a lethal effect on hydatid cysts--was administered preoperatively to patients affected by Echinococciasis, in order to sterilize cysts and prevent surgical contamination. Our results suggest that mebendazole treatment (1500 mg/die for 25 days) was effective in ten out of eleven cases; no major toxic effect was observed.
D001562:Benzimidazoles / Q000627:therapeutic use*; D004443:Echinococcosis / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D008463:Mebendazole / Q000627:therapeutic use*; D011292:Premedication
D001562:Benzimidazoles; D008463:Mebendazole