title: [Protective effect of ketotifen, investigations in allergic children with bronchial asthma (author's transl)].
abstract: 23 children with perennial allergic bronchial asthma were treated with ketotifen syrup/capsules. The required therapeutic dose was 0,03 mg/kg body weight twice daily. Improvement was observed in 16 of the 23 patients in part associated with decreased allergic manifestations in the eyes, nose and skin. Steroids could be discontinued in 3 of 7 patients. In 6 children transient tiredness resulted however only in one was a dose reduction necessary.
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D001249:Asthma / Q000188:drug therapy* / Q000276:immunology; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003371:Cough / Q000188:drug therapy; D004417:Dyspnea / Q000188:drug therapy*; D006801:Humans; D007665:Ketotifen; D010880:Piperidines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013256:Steroids / Q000627:therapeutic use; D013876:Thiophenes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D001993:Bronchodilator Agents; D010880:Piperidines; D013256:Steroids; D013876:Thiophenes; D007665:Ketotifen
vernacular_title: Untersuchungen zum protektiven Effekt von Ketotifen bei allergischen Kindern mit Asthma bronchiale.