Changes in blood neutrophil/lymphocyte ratio related to adrenocortical function in the horse.
Blood neutrophil/lymphocyte ratio and plasma cortisol levels were measured before and after (1) the injection of adrenocorticotrophic hormone (ACTH1-24) in 8 Thoroughbreds and (2) exercise in 5 Thoroughbreds in training. Plasma cortisol levels were significantly (P less than 0.01) increased within 60 mins of injection of ACTH1-24 and immediately after exercise. The mean neutrophil/lymphocyte ratio altered significantly (P less than 0.01) at 240 mins after ACTH1-24 administration and at 180 mins after a training gallop. A transient lymphocytosis occurred following exercise.
D000302:Adrenal Cortex / Q000502:physiology*; D000304:Adrenal Cortex Function Tests / Q000662:veterinary; D000818:Animals; D003366:Cosyntropin / Q000494:pharmacology; D005260:Female; D006736:Horses / Q000097:blood / Q000502:physiology*; D006854:Hydrocortisone / Q000097:blood; D008214:Lymphocytes / Q000166:cytology*; D008297:Male; D009504:Neutrophils / Q000166:cytology*; D005082:Physical Exertion
D003366:Cosyntropin; D006854:Hydrocortisone