title: Structure-activity relationships in the destruction of cytochrome P-450 mediated by certain ethynyl-substituted compounds in rats.
mesh_terms: D000480:Alkynes / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001711:Biotransformation; D002219:Carbamates / Q000378:metabolism / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005638:Fruit; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D010293:Pargyline / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D000480:Alkynes; D002219:Carbamates; C028997:5-decyne; C004359:barban; D003577:Cytochrome P-450 Enzyme System; D010293:Pargyline; C100198:ethinamate