title: Endodermal sinus tumor (yolk-sac carcinoma) of the orbit.
abstract: A 15-month-old boy with rapidly progressive proptosis had an unusual malignant germ-cell tumor of the orbit and nasopharynx identified as an endodermal sinus tumor (yolk-sac carcinoma). Endodermal sinus tumors arising in extra gonadal locations are highly malignant and generally lethal. The boy was treated with radiation and three-drug chemotherapy and has survived more than eight years.
mesh_terms: D005094:Exophthalmos / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D008649:Mesonephroma / Q000473:pathology* / Q000628:therapy; D009303:Nasopharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009918:Orbital Neoplasms / Q000473:pathology* / Q000628:therapy