Conversion of isopenicillin N into penicillin N in cell-free extracts of Cephalosporium acremonium.
In a cell-free system prepared by osmotic lysis of protoplasts of Cephalosporium acremonium, isopenicillin N is converted into penicillin N. The epimerase activity of the system is labile.
D000164:Acremonium / Q000201:enzymology / Q000378:metabolism*; D010406:Penicillins / Q000378:metabolism*; D019998:Racemases and Epimerases / Q000378:metabolism
D010406:Penicillins; D019998:Racemases and Epimerases; C006414:penicillin N