Effect of jejunoileal bypass operation and Billroth II resection on postprandial plasma pancreatic polypeptide release.
In five jejunoileal bypass-opeated subjects mean plasma pancreatic polypeptide (PP) values were significantly higher 15, 30, and 60 min. after start of a meal 2 weeks postoperatively, and 15 min. after start of a meal 6 weeks postoperatively, as compared with preoperative values. In a group of eight obese subjects, operated on with jejunoileal bypass 2-5 years ago, the postprandial plasma PP release tended to be higher than in an age-matched control group, the difference, however, being significant at 15 min. only. On the other hand, the postprandial plasma PP release in a group of six Billroth-II-resected patients was almost identical to that seen in an age-matched control group. It appears as though neither the antrum nor the small intestine is a prerequisite for a normal PP response to a mixed liquid test meal.
D000328:Adult; D005260:Female; D005502:Food; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy; D010191:Pancreatic Polypeptide / Q000097:blood*; D011184:Postoperative Period; D013270:Stomach / Q000601:surgery*; D013997:Time Factors
D010191:Pancreatic Polypeptide