Postural asymmetry and directionality of rotation in rats.
The hypothesis [12] that the direction of postural asymmetry can predict rotational side preferences caused by amphetamine, was tested. Postural asymmetry of male and female Wistar rats was assessed using four tests: (a) tail suspension, (b) tail holding, (c) tail pinch, and (d) walking on a narrow path. The tests were conducted prior to and after (+)-amphetamine (1 mg/kg, IP) administration. Rotational directionality was assessed in a rotometer. None of the tests predicted the direction of circling. The findings suggest that there is a multitude of systems contributing to asymmetric posture.
D000818:Animals; D003913:Dextroamphetamine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D011187:Posture; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects*
D003913:Dextroamphetamine