title: High incidence of sensitivity to yeast killer toxins among Candida and Torulopsis isolates of human origin.
abstract: Among yeast strains of human origin belonging to the genera Candida, Cryptococcus, Torulopsis, and Rhodotorula which were examined for killer and sensitive characteristics with killer and sensitive strains of Cryptococcus, Hansenula, Kluyveromyces, Pichia, Saccharomyces, and Torulopsis as screening organisms, a high incidence of sensitivity to killer toxins was observed within the genera Candida and Torulopsis. Of 142 strains tested, 116 strains distributed over all Candida and Torulopsis species examined were sensitive to one or more killers. Several new intergeneric killer-sensitive relationships are described. Furthermore, killing activity was exhibited by six strains of Candida (C. krusei, C. guilliermondii) and three strains of Torulopsis (T. glabrata).
mesh_terms: D002175:Candida / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D006801:Humans; D009181:Mycoses / Q000382:microbiology; D009183:Mycotoxins / Q000096:biosynthesis / Q000494:pharmacology*; D013045:Species Specificity; D015003:Yeasts / Q000187:drug effects / Q000378:metabolism
chemical_list: D009183:Mycotoxins