title: A rapid procedure to efficiently clean blenders repeatedly used to prepare dosed feed for bioassays.
abstract: An effective and economical procedure is described to clean blending equipment repeatedly used to prepare dosed feed for animal bioassays. The cleanup procedure was evaluated with 2 types of blenders against 10 test chemicals with a broad spectrum of polarities by separately spiking the agents into feed at various levels. Analytical data illustrating the level of contamination at each interval of the multi-step cleanup procedure are presented for each test chemical. Analytical chemical methods and efficiencies of the cleaning steps with the feed admixtures are discussed. The procedure was tested and adopted for use at the National Center for Toxicological Research (NCTR).
mesh_terms: D000821:Animal Feed / Q000592:standards*; D055598:Chemical Phenomena; D002621:Chemistry; D004396:Coloring Agents; D005506:Food Contamination / Q000517:prevention & control*; D014116:Toxicology / Q000295:instrumentation*
chemical_list: D004396:Coloring Agents