title: Improved detection and identification of basic drugs extracted from tissue using TLC.
abstract: Improved separation of methaqualone, lidocaine, cocaine, phencyclidine, phenacetin and methadone was achieved by a double development technique using dichloromethane:methyl ethyl ketone:ammonia (90:10:1.5 and 30:70:2). Improved identification of spots for some basic drugs was achieved after the traditional detection spray sequence with successive topical applications of: Marquis reagent, Mandelin reagent and a special ammonium molybdate fuming sulfuric acid reagent.
mesh_terms: D002855:Chromatography, Thin Layer; D003124:Colorimetry; D005554:Forensic Medicine; D006801:Humans; D008099:Liver / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000032:analysis*; D012997:Solvents
chemical_list: D004364:Pharmaceutical Preparations; D012997:Solvents