Diabetes insipidus in pregnancy as a first sign of a craniopharyngioma.
A patient is described who developed diabetes insipidus during pregnancy. During a revised Carter test performed at 36 wk gestation using DDAVP (1-desamino-8-D-arginine-vasopressin), uterine activity was recorded with a maximum activity of 120 Montevideo Units. The induction of uterine activity by DDAVP in our patient might be related to the high endogenous oxytocin levels or to the far advanced state of amenorrhea. Post partum, the patient reported decreased vision, and the visual fields were found to be abnormal. A neurosurgical procedure followed, and the diagnosis of craniopharyngioma was made.
D000328:Adult; D003397:Craniopharyngioma / Q000150:complications* / Q000601:surgery; D003894:Deamino Arginine Vasopressin / Q000097:blood / Q000494:pharmacology / Q000627:therapeutic use; D003919:Diabetes Insipidus / Q000209:etiology*; D005260:Female; D006801:Humans; D010121:Oxytocin / Q000097:blood / Q000502:physiology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D014590:Uterine Contraction / Q000187:drug effects
D010121:Oxytocin; D003894:Deamino Arginine Vasopressin