[Effect of determinant on formation of the complexes of hyperactivity foci in rabbit cerebral cortex].
With the use of weak strychnine solutions foci of enhanced excitability working in independent modes were created in the brain cortex of rabbits during acute experiments. The hyperactive excitability focus induced by concentrated solutions of strychnine played the role of a determinant structure. It enhanced the activity of other foci, united them into a single functional complex and determined the activity pattern of the entire complex. This complex of foci could be destroyed by depression of the determinant focus activity. Disconnection of any other (dependent) focus failed to destroy the complex. The results derived during the research on the new model confirm the general concept of the role played by the determinant structures in the activity of the central nervous system.
D000200:Action Potentials; D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000503:physiopathology*; D011817:Rabbits; D051381:Rats; D012640:Seizures / Q000503:physiopathology*; D013045:Species Specificity; D013331:Strychnine / Q000494:pharmacology
D013331:Strychnine
Obrazovanie kompleksov ochagov giperaktivnosti v kore mozga u krolikov pod vliianiem determinanty.