The effect of spironolactone pretreatment on the biliary excretion of digitoxin and its metabolites in male and female rats.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology; D004074:Digitoxin / Q000378:metabolism*; D005260:Female; D006900:Hydroxylation; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D013148:Spironolactone / Q000494:pharmacology*
D013148:Spironolactone; D003577:Cytochrome P-450 Enzyme System; D004074:Digitoxin