An interactive computer graphic system for 3-d stereoscopic reconstruction from serial sections: analysis of metastatic growth.
An interactive computer graphic system has been developed for 3-D reconstruction of stained serial sections. The system has been used for 3-D reconstruction of portions of mouse lung containing melanoma nodules. A stereoscopic color picture of a wire model of the reconstructed object is produced. The volume, surface area, and sphericity index of structures such as tumor nodules can be computed.
D000818:Animals; D003201:Computers / Q000379:methods; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology / Q000556:secondary; D008433:Mathematics; D008545:Melanoma / Q000473:pathology; D051379:Mice; D008961:Models, Structural; D009362:Neoplasm Metastasis / Q000473:pathology*; D009374:Neoplasms, Experimental / Q000473:pathology