Successful treatment of inorganic mercury neurotoxicity with N-acetyl-penicillamine despite an adverse reaction.
A man developed tremor after prolonged occupational exposure to metallic mercury. Treatment with N-acetyl-penicillamine resulted in marked clinical improvement despite untoward side effects. These side effects resolved after antihistamine treatment and conclusion of therapy. The decision to complete the therapeutic regimen despite an adverse reaction was justified by the striking clinical improvement.
D000368:Aged; D006801:Humans; D008297:Male; D008630:Mercury Poisoning / Q000188:drug therapy*; D009784:Occupational Diseases / Q000139:chemically induced / Q000188:drug therapy*; D010396:Penicillamine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
C010005:N-acetylpenicillamine; D010396:Penicillamine