title: GTG banding is not sufficient for the localization of breakpoints in translocations.
abstract: This study demonstrated that the GTG banding technique is not sufficient for the precise localization of breakpoints in translocations. Multiple banding techniques are required in cases with complex rearrangements before describing a so called "new syndrome'. Nevertheless, it is concluded that each banding technique has certain advantages, but GTG technique is the poorest choice.
mesh_terms: D000328:Adult; D001399:Azure Stains; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000175:diagnosis; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014178:Translocation, Genetic; D014357:Trypsin
chemical_list: D001399:Azure Stains; D014357:Trypsin