The use of surface spreading in the pachytene analysis of a human t (Y;17) reciprocal translocation.
This paper describes a human Y;17 reciprocal translocation in an azoospermic male ascertained through infertility. Meiotic studies made on both air-dried and surface-spread preparations are reported in addition to a somatic chromosome analysis carried out by high resolution R-banding on pro-metaphase chromosomes. The possible cause of spermatogenic disturbance in Y-autosome heterozygotes is discussed.
D002869:Chromosome Aberrations / Q000473:pathology*; D025063:Chromosome Disorders; D002875:Chromosomes / Q000648:ultrastructure; D002902:Chromosomes, Human, 16-18; D006801:Humans; D007248:Infertility, Male / Q000235:genetics / Q000473:pathology; D008297:Male; D008540:Meiosis; D014178:Translocation, Genetic