The Weibel-Palade Body in the diagnosis of endothelial tumors.
The Weibel-Palade body (WPB), a cytoplasmic marker for endothelial cells, was utilized in this ultrastructural study to confirm the light microscopic diagnosis in four different neoplasms of suspected endothelial origin. The WPB was prominent in benign endothelial neoplasms but was less so or absent in the malignant counterpart.
D000293:Adolescent; D000368:Aged; D002528:Cerebellar Neoplasms / Q000175:diagnosis; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D004727:Endothelium / Q000648:ultrastructure; D005260:Female; D006391:Hemangioma / Q000175:diagnosis* / Q000648:ultrastructure; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000648:ultrastructure; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis; D014625:Vaginal Neoplasms / Q000175:diagnosis