Evidence for in vivo methylation of the secondary amino antidepressant desipramine to imipramine in humans.
D000639:Amitriptyline / Q000097:blood; D001711:Biotransformation; D003866:Depressive Disorder / Q000097:blood* / Q000188:drug therapy; D003891:Desipramine / Q000097:blood* / Q000627:therapeutic use; D006801:Humans; D007099:Imipramine / Q000097:blood*; D008745:Methylation; D009661:Nortriptyline / Q000097:blood
D000639:Amitriptyline; D009661:Nortriptyline; D007099:Imipramine; D003891:Desipramine