A comparison of the immune response between two lines of chickens selected for differences in the weight of the bursa of Fabricius.
Experiments were designed to compare antibody-mediated immunity in two lines of 5-month-old chickens previously selected for a large or small bursa. After receiving a primary or secondary challenge with sheep-red-blood cells, bovine serum albumin, or dinitrophenyl, birds from the small bursa line (SBL) were significantly more efficient antibody producers than birds from the large bursa line (LBL). However, Immunoglobulin G synthesis by SBL birds was significantly lower than in LBL birds.
D000818:Animals; D000917:Antibody Formation; D002060:Bursa of Fabricius / Q000033:anatomy & histology; D002645:Chickens / Q000235:genetics / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006386:Hemagglutination Tests / Q000662:veterinary; D007114:Immunization / Q000662:veterinary; D007074:Immunoglobulin G / Q000096:biosynthesis; D008297:Male; D008623:Mercaptoethanol / Q000494:pharmacology; D009929:Organ Size; D012710:Serum Albumin, Bovine / Q000276:immunology; D012756:Sheep / Q000276:immunology
D007074:Immunoglobulin G; D012710:Serum Albumin, Bovine; D008623:Mercaptoethanol