Plasma fibrinogen concentration in ABO-hemolytic disease of the newborn.
Plasma fibrinogen and total serum proteins were measured in infants affected by ABO-hemolytic disease and in normal infants' cord blood and blood taken 48 h after birth. The average plasma fibrinogen concentrations in the blood of infants with ABO-hemolytic disease was 447.36 mg/dl as compared with 267.09 mg/dl (p less than 0.005) in cord blood and 313.82 mg/dl (p less than 0.005) in blood samples taken 48 h after birth. A simple 'autoagglutination' test is found to be helpful when establishing the diagnosis of ABO-hemolytic disease.
D000017:ABO Blood-Group System; D000372:Agglutination Tests; D001323:Autoantibodies; D001663:Bilirubin / Q000097:blood; D001798:Blood Proteins; D003298:Coombs Test; D004899:Erythroblastosis, Fetal / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005340:Fibrinogen; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
D000017:ABO Blood-Group System; D001323:Autoantibodies; D001798:Blood Proteins; D005340:Fibrinogen; D001663:Bilirubin