[Mechanisms of development of pneumonia after burns].
Experiments in rats (burns followed by intratracheal infection with a staphylococcus suspension) were used to study association between disorders in phagocytosis of polymorphonuclear leukocytes and alveolar macrophages and histological manifestations of the inflammatory-infectious process in the lungs. Different resistance of micro- and macrophage cells to burn trauma was demonstrated. Disorders in the phagocytic properties of the cells were shown to precede the development of the inflammatory-infectious process documented at the tissue level.
D000818:Animals; D002056:Burns / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D009504:Neutrophils / Q000276:immunology*; D010585:Phagocyte Bactericidal Dysfunction / Q000150:complications; D010587:Phagocytosis; D011023:Pneumonia, Staphylococcal / Q000209:etiology* / Q000473:pathology; D051381:Rats
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