title: Experimental atherosclerosis in rabbits fed cholesterol-free diets. Part 9. Beef protein and textured vegetable protein.
abstract: Rabbits were fed a semipurified diet containing 40% sucrose, 25% protein, 15% fiber and 14% tallow. The proteins fed were beef (B), textured vegetable protein (TVP) and casein (C). One diet contained beef-TVP (1 : 1) and in another a soy carbohydrate fraction, spent flakes, was added to the diet; it provided 2.2% protein and 10.5% fiber. TVP provided 6.4% soluble carbohydrate and 10.5% fiber. The diets were fed from 8 months. Diets containing beef protein or casein gave significantly higher serum cholesterol levels and atherosclerosis and significantly lower serum HDL-cholesterol than did the other 3 diets. The beef-TVP (1 : 1) diet gave low serum cholesterol (67% below beef) levels and atherosclerosis (47% below beef). This effect is probably due to the protein. The diet containing spent flakes gave low serum cholesterol levels (44% below beef) and atherosclerosis (45% below beef). This effect is attributed to the different fiber. The lowest serum cholesterol levels and least severe atherosclerosis were observed in the rabbits fed TVP.
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology*; D001835:Body Weight; D002364:Caseins / Q000008:administration & dosage; D002417:Cattle; D002482:Cellulose; D002784:Cholesterol / Q000172:deficiency*; D008099:Liver / Q000032:analysis / Q000033:anatomy & histology; D008297:Male; D008460:Meat; D009929:Organ Size; D014674:Plant Proteins, Dietary / Q000008:administration & dosage; D011817:Rabbits; D013025:Glycine max
chemical_list: D002364:Caseins; D014674:Plant Proteins, Dietary; D002482:Cellulose; D002784:Cholesterol