Maternal morbidity due to beta-adrenergic therapy. Pre-existing cardiomyopathy aggravated by fenoterol.
In the 32nd wk, fenoterol was administered to a patient during her first pregnancy because of premature rupture of the membranes and uterine contractions after 2 wk of medication. At 8 microgram/min of fenoterol, total irregularity of the maternal pulse occurred. In the 35th wk, cesarean section had to be performed because of fetal asphyxia at 5 cm of cervical dilatation. Intensive care treatment of the mother was necessary during the postoperative phase. The diagnosis of pre-existing congestive cardiomyopathy was made. Non-invasive examination of the heart is advised before beta-adrenergic drugs are given.
D000328:Adult; D009202:Cardiomyopathies / Q000139:chemically induced*; D004983:Ethanolamines / Q000009:adverse effects*; D005260:Female; D005280:Fenoterol / Q000009:adverse effects* / Q000378:metabolism; D006801:Humans; D007752:Obstetric Labor, Premature / Q000188:drug therapy / Q000517:prevention & control; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000139:chemically induced*
D004983:Ethanolamines; D005280:Fenoterol