Two-month follow-up of the changes in vitreal constituents after argon laser coagulation of the retina in rabbits.
The response of the vitreous after panretinal argon laser photocoagulation was followed over a period of 60 days. Two phases can be discerned. An an immediate reaction to the disturbance of the blood-retinal barrier at the site of the pigment epithelium the total protein content and malate dehydrogenase activity rise sharply within 3 days, 4- to 5-fold above a normal. The more protracted increase of lysosomal enzyme activities which reach their peak heigh after 14 days only, can be attributed to the action and proliferation of phagocytic cells. 2 months after treatment all parameters have returned to their normal levels.
D000110:Acetylcholinesterase / Q000032:analysis; D000135:Acid Phosphatase / Q000032:analysis; D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis; D002402:Cathepsin D; D002403:Cathepsins / Q000032:analysis; D005136:Eye Proteins / Q000032:analysis; D005500:Follow-Up Studies; D005696:Galactosidases / Q000032:analysis; D006603:Hexuronic Acids / Q000032:analysis; D053685:Laser Therapy; D007834:Lasers; D008291:Malate Dehydrogenase / Q000032:analysis; D008361:Mannosidases / Q000032:analysis; D011817:Rabbits; D012160:Retina / Q000601:surgery*; D013997:Time Factors; D014822:Vitreous Body / Q000032:analysis*
D005136:Eye Proteins; D006603:Hexuronic Acids; D008291:Malate Dehydrogenase; D000110:Acetylcholinesterase; D000135:Acid Phosphatase; D005696:Galactosidases; D008361:Mannosidases; D002403:Cathepsins; D002402:Cathepsin D; D001205:Ascorbic Acid