title: Nonsurgical management of focal intracranial infection.
abstract: Fourteen patients with focal suppurative intracranial inflammatory disease were initially treated nonsurgically. Eleven received antibiotics and corticosteroids, and three received only antibiotics. In 12, there was both clinical and computerized tomography (CT) resolution. In two patients, evolution to ring-enhancing encapsulated lesion was subsequently proved to be an encapsulated abscess that required surgical drainage, after which there was a good clinical outcome. In four patients, complete CT resolution was not evident for 2 to 6 months after completion of antibiotic therapy, although the patients had become neurologically asymptomatic prior to this.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005490:Focal Infection / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents