Establishment and characterization of a murine hybridoma secreting monoclonal anti-DNA autoantibody.
Twenty-five clones of hybridoma cells secreting anti-DNA autoantibodies were isolated after fusions between plasmacytoma cells (P3-x 63 Ag 8.653) and spleen cells from nonimmunized autoimmune NZB/NZW F1 (B/W) mice. A monoclonal anti-DNA autoantibody was immunochemically analyzed.
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D001323:Autoantibodies; D001345:Autoradiography; D002417:Cattle; D002459:Cell Fusion; D002460:Cell Line; D002999:Clone Cells / Q000276:immunology; D004247:DNA / Q000276:immunology*; D005260:Female; D006822:Hybrid Cells / Q000276:immunology* / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy
D001323:Autoantibodies; D004247:DNA