title: Glucose sensor characteristics for miniaturized portable closed-loop insulin delivery: a step toward implantation.
abstract: An implantable glucose sensor must be free of baseline and sensitivity drift. To our knowledge, a drift-free glucose sensor with fast response time is not currently available. We are therefore proposing a miniature extracorporeal glucose sensor with access to the vascular system as a practical step toward implantation. This sensor could use existing technology to form the basis of a patient-wearable closed-loop system.
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D004567:Electrodes, Implanted; D004800:Enzymes, Immobilized; D005949:Glucose Oxidase; D007332:Insulin Infusion Systems; D011048:Polarography / Q000295:instrumentation
chemical_list: D001786:Blood Glucose; D004800:Enzymes, Immobilized; D005949:Glucose Oxidase