Fulminant amebic meningoencephalitis due to Acanthamoeba.
A 57-year-old chronically immunosuppressed woman with systemic lupus erythematosus developed fulminant meningoencephalitis due to Acanthamoeba castellanii. Amebic trophozoites were also found in the lungs, suggesting a primary pulmonary focus of infection. This case illustrates that Acanthamoeba can cause a fulminant, rapidly fatal meningoencephalitis, as well as the previously reported chronic granulomatous meningoencephalitis.                                                                                 X
D000562:Amebiasis / Q000382:microbiology / Q000473:pathology; D005260:Female; D006249:Hartmannella / Q000382:microbiology; D006801:Humans; D008590:Meningoencephalitis / Q000382:microbiology / Q000473:pathology*; D008875:Middle Aged