GH3 rat pituitary tumor cells are deficient in hypoxanthine-guanine phosphoribosyl transferase activity.
D000630:Aminopterin / Q000494:pharmacology; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D002999:Clone Cells; D004261:DNA Replication; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency*; D007700:Kinetics; D009374:Neoplasms, Experimental / Q000201:enzymology / Q000235:genetics; D010911:Pituitary Neoplasms / Q000201:enzymology* / Q000235:genetics; D051381:Rats; D013866:Thioguanine / Q000494:pharmacology
D007041:Hypoxanthine Phosphoribosyltransferase; D013866:Thioguanine; D000630:Aminopterin