Patch test sensitization to D & C yellow No. 11 and simultaneous reaction to quinoline yellow.
The quinoline color D & C Yellow No. 11 was added to a standard test series. Of 88 patients tested with 1% in PEG, four showed unexplained positive test reactions. One patient had a "flare-up" reaction after 14 days. At rechallenge he reacted to a dilution down to 0.00001%. Simultaneous reaction with the chemically related commonly used food color Quinoline Yellow (E 104) suggests cross-sensitivity.
D000328:Adult; D003877:Dermatitis, Contact / Q000276:immunology; D005505:Food Coloring Agents / Q000009:adverse effects / Q000276:immunology*; D006801:Humans; D008297:Male; D010328:Patch Tests; D011804:Quinolines / Q000276:immunology*; D012882:Skin Tests
D005505:Food Coloring Agents; D011804:Quinolines; C019303:quinoline yellow; C027012:2-((2'-quinolinyl)-1,3-indandione)