HLA-B27, arthritis and Yersinia enterocolitica infection.
Over a 3 1/2-yr period 25 cases of Yersinia enterocolitica arthritis were observed. This is a frequency of about 1% of the new patients seen at our Rheumatology Clinic. The histocompatibility antigen HLA-B27 was found in 14 of the 25 patients with Yersinia arthritis (56%). There was no difference in duration of disease, joint symptoms or laboratory data between the HLA-B27 positive or negative group. Six cases had a disease course longer than 1 yr. Four of them had a disease onset before the age of 16 yr and all cases had knee joint involvement. Our findings are discussed in relation to reports from other centers.
D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004487:Edema / Q000150:complications; D005260:Female; D006680:HLA Antigens; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008684:Metatarsus / Q000000981:diagnostic imaging; D008875:Middle Aged; D011859:Radiography; D013585:Synovitis / Q000150:complications; D013997:Time Factors; D014606:Uveitis, Anterior / Q000150:complications; D015009:Yersinia Infections / Q000150:complications*
D006680:HLA Antigens