Synthesis of a unique polypeptide in measles virus-infected BGM cells.
In measles virus-infected BGM (African green monkey kidney) cells, a unique polypeptide (84K) was identified. This polypeptide was not found in other cell lines examined and could be immunoprecipitated with anti-NP monoclonal antibody. Peptide mapping studies confirmed that it contained all the peptides of the 60K NP plus several additional ones. Pulse-chase experiments failed to establish it as a precursor of the 60K polypeptide. The possible origin of this protein is discussed.
D000818:Animals; D000911:Antibodies, Monoclonal; D002460:Cell Line; D002522:Chlorocebus aethiops; D008459:Measles virus / Q000378:metabolism*; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis; D014764:Viral Proteins / Q000032:analysis / Q000096:biosynthesis* / Q000276:immunology
D000911:Antibodies, Monoclonal; D010455:Peptides; D014764:Viral Proteins