[In-vitro action of manganese on platelet aggregation. Hints on prevention].
The AA. carried out some researches on PAT by adding to the plasma the manganic chloride in mu molar, c molar and m molar solution. The platelet aggregation induced by ADP, adrenaline, collagen and thrombofax, makes powerful in presence of manganese salt. The presence of manganic chloride modifies the platelet aggregation in a hyper-aggregated way, slowly and tardly, but clearly. The practical application of experimental results in vitro is certainly very important for prevention planning.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D003094:Collagen / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology; D006801:Humans; D008345:Manganese / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D013925:Thromboplastin / Q000494:pharmacology
C005515:Thrombofax; D008345:Manganese; D000244:Adenosine Diphosphate; D003094:Collagen; D013925:Thromboplastin; D004837:Epinephrine
Azione in vitro del manganese sull'aggregazione piastrinica. Spunti di prevenzione.