Influence of biological fluids on the release of 125I from povidone-iodine.
A study on the influence of vaginal smear, blood cells and human plasma on the release of 125I from povidone-iodine was conducted. The total amounts of iodine released from povidone-iodine in presence of saliva and vaginal smear are 9.51% and 5.99%, respectively, as compared to 5.9 in normal saline solution. Blood cells and plasma were found to take up 54.2 and 80.1% of iodine released from povidone-iodine. The possible effect of these fluids on the antimicrobial activity of povidone-iodine is discussed.
D001773:Blood Cells / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism; D001826:Body Fluids / Q000378:metabolism*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism*; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000378:metabolism*; D012463:Saliva / Q000378:metabolism; D014626:Vaginal Smears
D001798:Blood Proteins; D007457:Iodine Radioisotopes; D011206:Povidone-Iodine; D011205:Povidone