IgE antibody levels to ingested soya protein determined in a normal adult population.
Levels of soy protein-specific IgE were measured in a normal adult population (seventy-four males, and fifteen females) who ingested soya-containing and control diets during two 4-week periods. Increases in soya-specific IgE were observed for some individuals following ingestion of the soya-containing diet, and for the female group the increase in soya-specific IgE was statistically significant (P = 0.02). The increase of soya-specific IgE was small and led to lower levels than that associated with adverse effects. The increase in soya-specific IgE in the female group was accompanied by a significant increase (P = 0.02) in total immunoglobulin A. Changes in the level of soy-specific haemagglutinating antibody, soya-specific IgG, IgA and IgM as measured by ELISA and the immunoconglutinin titre could not be related to ingestion of the soya-containing diet.
D000918:Antibody Specificity; D003168:Complement Fixation Tests; D004032:Diet; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000096:biosynthesis* / Q000502:physiology; D008297:Male; D012275:Oryza / Q000276:immunology; D006109:Poaceae / Q000276:immunology; D011852:Radioallergosorbent Test; D012737:Sex Factors; D013025:Glycine max / Q000276:immunology*; D014908:Triticum / Q000276:immunology
D007073:Immunoglobulin E