Progress toward a potentially implantable, enzyme-based glucose sensor.
Our efforts toward the development of a potentially implantable, enzyme-based glucose sensor have concentrated on understanding in sufficient detail the most important component, the enzyme-containing membrane. We describe here some features that this membrane must have to operate as a constituent of a chronically implanted sensor. A model of reaction and diffusion within the membrane is outlined and methods of membrane characterization are reviewed.
D001692:Biological Transport; D001786:Blood Glucose / Q000032:analysis; D004567:Electrodes, Implanted; D004800:Enzymes, Immobilized; D005947:Glucose / Q000032:analysis*; D008567:Membranes, Artificial; D008956:Models, Chemical; D010100:Oxygen / Q000097:blood
D001786:Blood Glucose; D004800:Enzymes, Immobilized; D008567:Membranes, Artificial; D005947:Glucose; D010100:Oxygen