title: [Spasmolytic and contractile effects of a combination product from plants on the smooth muscle of the guinea pigs].
abstract: The study of the actions of Urol, (Extr. Rad. Rubiae tinct. spir., Extr. Sem. Ammeos visnagae spir, Extr, Herb. Virgaureae spir., Extr. Rad. Taraxaci c. Herb. spir., escin) on guinea pig ileum revealed two different effects: In ileum not pretreated, Urol, particularly the Rad, taraxaci ingredients, increased motility. In contrast, in acetylcholine-pretreated ileum, Urol, particularly the Herba virgaurea and Ammi visnaga ingredients, exhibited spasmolytic activity. The significance of these results, particularly with respect to the expulsion of urinary crystals by Urol, is discussed.
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects*; D010276:Parasympatholytics; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D010276:Parasympatholytics; D010936:Plant Extracts; D000109:Acetylcholine
vernacular_title: Spasmolytische und kontraktile Einflüsse eines pflanzlichen Kombinationspräparates auf die glatte Muskulatur des isolierten Meerschweinchendarms.