2-Hydroxylation of estrogens in the brain participates in the initiation of the preovulatory LH surge in the rat.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D019363:Cytochrome P-450 CYP1A1; D004967:Estrogens / Q000378:metabolism*; D004971:Estrus; D005260:Female; D007986:Luteinizing Hormone / Q000378:metabolism*; D008861:Microsomes / Q000201:enzymology; D008928:Mitochondria / Q000201:enzymology; D011247:Pregnancy; D051381:Rats; D013250:Steroid Hydroxylases / Q000378:metabolism*; D013574:Synaptosomes / Q000201:enzymology
D004967:Estrogens; D007986:Luteinizing Hormone; D013250:Steroid Hydroxylases; D019363:Cytochrome P-450 CYP1A1; C020120:estrogen 2-hydroxylase