[Effect of alcohol on glial cells].
The reaction of the cerebral cortex glia to alcohol was studied in rats subjected to alcoholic intoxication. Use was made of the Nissl and Golgi method. In 20 days of alcohol intoxication (a 35% solution) the amount of the perineuronal and total glia, as calculated in stratum V of the sensomotor cortex, was found to increase, this increase being statistically significant. This was accompanied by changes of the glia cell metabolism (as was indicated by intensification of the glia impregnation properties) and by formation of compensatory glia-dendrite "contacts", probably, for maintaining the vital activity of the alcohol-affected neurons. Later (in 2, 4, 8, 12, and 15 months), along with the decrease of the number of neurons and the proliferation of the glia, there appeared signs of the latter's dystrophic changes. This is undoubtedly reflected on the cerebral cortex function.
D000437:Alcoholism / Q000473:pathology*; D000818:Animals; D001253:Astrocytes; D002452:Cell Count; D006801:Humans; D009044:Motor Cortex / Q000473:pathology*; D009457:Neuroglia; D009474:Neurons; D009836:Oligodendroglia; D051381:Rats; D013003:Somatosensory Cortex / Q000473:pathology*
O vliianii alkogolia na glial'nye kletki.