[Malignant mediastinal embryoma. A case with pulmonary metastasis. Complete remission after chemotherapy].
Rapid increase in growth of a pulmonary metastasis following incomplete excision of a malignant mediastinal embryoma was treated by multiple chemotherapy combining platinum derivatives, actinomycin B, bleomycin, and vincaleucoblastin. Complete remission was obtained. These extremely rare tumours have a histological appearance close to that of testicular tumours. Until recently, their prognosis was such that therapy appeared to be of no avail, but this has been modified by new chemotherapy schedules including, more particularly, the use of platinum.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D011379:Prognosis; D013724:Teratoma / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary
D000970:Antineoplastic Agents
Embryome malin du médiastin. Une observation avec métastase pulmonaire. Rémission complète après chimiothérapie.