Aplastic anemia associated with estrus in pet ferrets.
Aplastic anemia in association with estrus was diagnosed in 6 pet ferrets. The ferrets had been examined because of anorexia, depression, and lethargy of 2-5 days' duration. Consistent clinical findings were pale mucous membranes and enlargement of the vulva. Hemorrhages were found in 3 ferrets. Hematologic findings included severe anemia, thrombocytopenia, granulocytopenia, and hypocellularity of the bone marrow. The aplastic anemia was attributed to prolonged estrogenic exposure in ferrets with protracted estrus.
D000741:Anemia, Aplastic / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D000829:Animals, Domestic; D001853:Bone Marrow / Q000473:pathology; D002335:Carnivora / Q000502:physiology*; D004971:Estrus; D005260:Female; D005289:Ferrets / Q000097:blood / Q000502:physiology*; D011247:Pregnancy