title: Effects of pyridoxine-pyrrolidon-carboxylate on hepatic and cerebral ATP levels in ethanol treated rats.
abstract: ATP levels were measured in the liver and brain of rats acutely intoxicated with ethanol. The pretreatment of the animals with pyridoxine-pyrrolidon carboxylate (Metadoxine) prevented the marked fall in ATP concentration caused by ethanol in both organs.
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis*; D000435:Alcoholic Intoxication / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D004338:Drug Combinations; D006801:Humans; D008099:Liver / Q000032:analysis* / Q000187:drug effects; D008297:Male; D011736:Pyridoxine / Q000494:pharmacology*; D011760:Pyrrolidinones / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D011760:Pyrrolidinones; D000255:Adenosine Triphosphate; D011736:Pyridoxine; D011761:Pyrrolidonecarboxylic Acid