title: Investigation of the mechanism of perforation of an intrauterine device in pigs and dogs.
abstract: In the last few years the risk of perforations in connection with the insertion and later use of intrauterine devices (IUDs) has been the subject of much discussion in Sweden. In this experimental study, which was carried out on five pigs and nine dogs and in which four different types of IUDs were used, the following clinical situations encountered in women were simulated: IUD in correct position in the uterus, IUD in an adverse position in the uterus, and IUD more or less inserted through the uterine wall. The animals were observed for 3 to 6 months. The findings indicate that, when perforation occurs, it is most probably ascribable to the insertion procedure.
mesh_terms: D000818:Animals; D004285:Dogs; D004716:Endometritis / Q000209:etiology; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D007249:Inflammation; D007434:Intrauterine Devices / Q000009:adverse effects*; D007435:Intrauterine Devices, Copper / Q000009:adverse effects; D013552:Swine; D014599:Uterus / Q000378:metabolism