Metabolic fate of [14C]dieldrin in Schistocerca gregaria with particular reference to the nervous system.
1. In the metabolism of [14C]dieldrin in Schistocerca gregaria, four metabolites of dieldrin were detected. Three of these have been identified as cis-aldrindiol, trans-aldrindiol and seco-aldrin dicarboxylic acid. 2. Apart from the formation of cis and trans-aldrindiol, another metabolite, M1, was detected in the nervous system. 3. The uptake of the dose of dieldrin was maximal in nerve cords followed by thoracic muscles and gut. Degradation of dieldrin was, however, not detected in thoracic muscles.
D000818:Animals; D001711:Biotransformation; D004026:Dieldrin / Q000378:metabolism*; D004149:Dioxoles / Q000494:pharmacology; D005243:Feces / Q000032:analysis; D006110:Grasshoppers / Q000378:metabolism*; D008297:Male; D009420:Nervous System / Q000378:metabolism*; D013997:Time Factors; D014018:Tissue Distribution
D004149:Dioxoles; C100180:sesamex; D004026:Dieldrin