[Histoautoradiographic analysis of the liver of albino rats treated with low doses of vinyl chloride].
The authors examined experimental albino rats, treated with low vinyl chloride doses via electronmicroscopic autoradiography by marking with thymidine H3. It was established that no blastic processes developed in liver with the low vinyl chloride doses used. THe authors found a certain inhibition of the plastic functions of hepatocytes, manifested by the diminished marking of thymidine H3 in the nuclei of hepatocytes and Kupffer cells, being of essential importance for an eventual development of the blastic processes in liver.
D000818:Animals; D001345:Autoradiography; D002455:Cell Division; D004305:Dose-Response Relationship, Drug; D008099:Liver / Q000187:drug effects* / Q000473:pathology / Q000648:ultrastructure; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced; D008854:Microscopy, Electron; D051381:Rats; D014752:Vinyl Chloride / Q000633:toxicity*; D014753:Vinyl Compounds / Q000633:toxicity*
D014753:Vinyl Compounds; D014752:Vinyl Chloride
Khistoavtoradiografichni izsledvaniia na cherniia drob na beli plukhove, tretirani s malki dozi vinilkhlorid.