title: Pityriasis rubra pilaris and and retinol-binding protein.
abstract: Serum levels of retinol-binding protein (the specific carrier of vitamin A) were measured in eleven patients with pityriasis rubra pilaris and in some of their close relatives. The level of retinol-binding protein was markedly reduced in every patient, and in some of the relatives. It is postulated that defective synthesis of retinol-binding protein is a biochemical marker for pityriasis rubra pilaris, probably transmitted as a Mendelian dominant.
mesh_terms: D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010916:Pityriasis Rubra Pilaris / Q000097:blood* / Q000235:genetics; D012177:Retinol-Binding Proteins / Q000097:blood*
chemical_list: D012177:Retinol-Binding Proteins