Symptomatological classification in the development of stroke in stroke-prone spontaneously hypertensive rats.
The developmental course of cerebrovascular diseases was examined by comparative neurological and pathological studies in stroke-prone SHR (SHRSP) which died spontaneously or were sacrificed. Behavioral status during their life span could be simply divided into 4 patterns, i.e., "no abnormalities", "irritable", "lethergic" and "akinetic" named Grades 0, I, II and III, respectively (Yamori's Classification). Grades I, II and III of behavioral status corresponded well to symptomato-pathoanatomically divided 3 stages (relating to brain edema), i.e., Stages I, II and III, respectively.
D000818:Animals; D001921:Brain / Q000473:pathology; D001929:Brain Edema / Q000150:complications / Q000401:mortality; D002561:Cerebrovascular Disorders / Q000145:classification* / Q000175:diagnosis / Q000209:etiology; D004195:Disease Models, Animal; D004569:Electroencephalography; D004677:Encephalocele / Q000150:complications; D006801:Humans; D006948:Hyperkinesis / Q000150:complications; D006973:Hypertension / Q000150:complications*; D008297:Male; D009461:Neurologic Manifestations; D051381:Rats; D011919:Rats, Inbred Strains; D012894:Sleep Stages