Irreversible inhibitors of GABA transaminase induce antinociceptive effects and potentiate morphine.
D000612:4-Aminobutyrate Transaminase / Q000037:antagonists & inhibitors*; D000480:Alkynes; D000614:Aminocaproates / Q000494:pharmacology; D000818:Animals; D001259:Ataxia / Q000139:chemically induced; D001923:Brain Chemistry / Q000187:drug effects; D004357:Drug Synergism; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D009020:Morphine / Q000494:pharmacology*; D009021:Morphine Dependence / Q000503:physiopathology; D009270:Naloxone / Q000494:pharmacology; D010146:Pain / Q000188:drug therapy*; D051381:Rats; D013237:Stereoisomerism; D000637:Transaminases / Q000037:antagonists & inhibitors*; D020888:Vigabatrin; D005680:gamma-Aminobutyric Acid / Q000032:analysis
D000480:Alkynes; D000614:Aminocaproates; D009270:Naloxone; D005680:gamma-Aminobutyric Acid; C013785:4-amino-5-hexynoic acid; D009020:Morphine; D000637:Transaminases; D000612:4-Aminobutyrate Transaminase; D020888:Vigabatrin