[Dynamics of the change in the level of corticosteroids in the blood and tissues and of catecholamines in the urine of rats in the process of developing an adaptation reaction to emotional stress].
Experiments on male rats were carried out. Prolonged emotional stress was produced by periodic pain stimulation with a weak electric current. Examination of 11-hydroxycorticosteroids (11-HOCS) in the blood and tissue levels has shown an increase in the concentration of total and free 11-HOCS during the first 30 days. By the 130th day 11-HOCS content abruptly fell in the blood and tissues despite the fact that the reserve potentialities of the adrenal cortex (ACTH test) were within normal. On the contrary, the catecholamine concentration in the animals' urine sharply rose by the end of the experiments.
D000222:Adaptation, Physiological; D000305:Adrenal Cortex Hormones / Q000378:metabolism*; D000818:Animals; D002395:Catecholamines / Q000652:urine*; D004558:Electric Stimulation; D005609:Free Radicals; D006801:Humans; D008297:Male; D011485:Protein Binding; D051381:Rats; D013315:Stress, Psychological / Q000503:physiopathology*; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D002395:Catecholamines; D005609:Free Radicals
Dinamika izmeneniia urovnia kortikosteroidov v krovi i tkaniakh i katekholaminov v moche krys v protsesse razvitiia reakstii adaptatsii k émotsional'nomu napriazheniiu.