title: Isolation of drugs from post mortem specimens with the automated sample processor. Part I. Barbiturate derivatives.
abstract: Employing an automated sample processor, barbiturate positive tissue homogenates were analyzed to yield gas and liquid chromatographic data. Excellent quality extracts were produced that could be assayed by either GC/NPD or HPLC. Good precision and accuracy was found (CV 2-5%) with approximately 200 mg of tissue sample. The technique has been applied to authentic post mortem tissues and fluids.
mesh_terms: D001322:Autoanalysis / Q000295:instrumentation; D001463:Barbiturates / Q000097:blood / Q000302:isolation & purification*; D001923:Brain Chemistry; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D008099:Liver / Q000032:analysis
chemical_list: D001463:Barbiturates