Seral, uterine and fetal salicylate concentrations after oral administration.
Salicylate concentrations in serum, endometrium, myometrium and fetus were determined 3 h after an oral dose of 1 000 mg of acetylsalicylic acid. The material consisted of 19 females (11 for legal abortion and 8 for operative treatment of fibroids). Tissue salicylate concentrations were at a level at which prostaglandin synthetase is inhibited.
D000284:Administration, Oral; D000328:Adult; D001241:Aspirin / Q000378:metabolism*; D004717:Endometrium / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008431:Maternal-Fetal Exchange; D009215:Myometrium / Q000378:metabolism; D011247:Pregnancy; D014599:Uterus / Q000378:metabolism*
D001241:Aspirin