[Isolated liver perfusion with 5-fluorouracil (5-FU) in the human].
In two patients with liver metastases from colorectal cancer an isolated perfusion of the liver with 5-fluorouracil was performed. The primary tumors had been resected 5 weeks and 11 months before the perfusion treatment. By means of special cannulation system the hepatic artery and the portal vein were both arterialized. The patients recovered well after the operation. Sonographic measurements of the metastases showed colliquation areas in the tumours postoperatively.
D010478:Chemotherapy, Cancer, Regional Perfusion; D003110:Colonic Neoplasms / Q000188:drug therapy*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy*; D012007:Rectum / Q000601:surgery
D005472:Fluorouracil
Die isolierte Leberperfusion mit 5-Fluorouracil (5-FU) beim Menschen.