Severe and prolonged poisoning by fenthion. Significance of the determination of the anticholinesterase capacity of plasma.
A case of acute poisoning by oral ingestion of fenthion is reported. The different clinical signs, especially the delayed and prolonged symptomatology, are described. The various types of therapeutic measures (gastric lavage with charcoal, administration of atropine, Toxogonine, lyophilized human cholinesterase, and fresh plasma and exchange transfusion) are discussed. Correlation studies between clinical signs and plasma and erythrocyte cholinesterase activities are presented together with plasma fenthion levels and the anticholinesterase capacity of the patient's plasmas.
D000328:Adult; D002606:Charcoal / Q000627:therapeutic use; D002800:Cholinesterase Inhibitors / Q000097:blood / Q000378:metabolism; D002802:Cholinesterases / Q000097:blood / Q000378:metabolism*; D005284:Fenthion / Q000097:blood / Q000506:poisoning*; D006801:Humans; D008297:Male; D013997:Time Factors
D002800:Cholinesterase Inhibitors; D002606:Charcoal; D005284:Fenthion; D002802:Cholinesterases