A pharmacological study of cefaclor in the newborn infant.
The absorption and excretion of cefaclor were studied in 10 newborn infants. A mean peak serum concentration of 7.7 microgram/ml was achieved at 1 hour after an oral dose of 7.5 mg/kg. It is concluded that cefaclor is a well absorbed and tolerated cephalosporin for use in newborn infants.
D001424:Bacterial Infections / Q000382:microbiology; D002433:Cefaclor / Q000009:adverse effects / Q000378:metabolism*; D002506:Cephalexin / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000378:metabolism*; D007408:Intestinal Absorption; D007700:Kinetics; D011247:Pregnancy
D002433:Cefaclor; D002506:Cephalexin