[Prevention of stress injuries to the heart by using preliminary adaptation to altitude hypoxia].
Reduced contractile function of the isolated heart and increased flow of CPK from it into the perfusate were observed in animals who had suffered an emotional-pain stress in the form of anxiety neurosis; the hupoxic test caused more marked changed in these animals. Preliminary adaptation to high altitude hypoxia prevented the damaging effect of stress according to the criterion of enzyme escape; there was no deficiency of contractile function.
D000222:Adaptation, Physiological; D000532:Altitude Sickness / Q000503:physiopathology*; D000818:Animals; D001273:Atmosphere Exposure Chambers; D003402:Creatine Kinase / Q000378:metabolism; D004789:Enzyme Activation; D006335:Heart Injuries / Q000517:prevention & control*; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D009200:Myocardial Contraction; D009206:Myocardium / Q000201:enzymology; D051381:Rats; D013315:Stress, Psychological / Q000517:prevention & control*; D013997:Time Factors
D003402:Creatine Kinase
Preduprezhdenie stressornykh povrezhdeniĭ serdtsa s pomoshch'iu predvaritel'noĭ adaptatsii k vysotnoĭ gipoksii.