title: Growth hormone and isolation-induced aggression in wild male mice.
abstract: Aggressive behavior, motor activity and defecation were examined simultaneously in wild male mice following daily growth hormone (GH) administration. GH was found to increase isolation-induced aggression by increasing fighting duration and decreasing latency to fight. There was no influence on non-aggressive motor activity nor on the defecation rate, a presumed parameter of emotionality. The results provide evidence of behavioral properties of GH. The mechanism of this action is discussed in terms of a possible direct central action of GH, not mediated by glucagon, insulin, secretin and gastrin.
mesh_terms: D000374:Aggression / Q000187:drug effects*; D000818:Animals; D000835:Animals, Wild; D003672:Defecation / Q000187:drug effects; D013006:Growth Hormone / Q000494:pharmacology*; D006801:Humans; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D012934:Social Isolation
chemical_list: D013006:Growth Hormone