Exposure indices for epidemiological surveillance of carcinogenic agents in an industrial chemical environment.
A prospective system for establishing chemical exposure indices was developed and implemented for 22 chemicals used at a Louisville chemical plant. Validation of the indices was done statistically using industry-related cancer (liver angiosarcoma) and worker-matched controls. A rank ordered system for exposures was used to identify a relationship between the occurrence of disease and the presence of a suspect chemical used in the industrial environment.
D002273:Carcinogens / Q000032:analysis* / Q000633:toxicity; D002617:Chemical Industry; D004812:Epidemiologic Methods; D006394:Hemangiosarcoma / Q000139:chemically induced; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced*; D014752:Vinyl Chloride / Q000032:analysis
D002273:Carcinogens; D014752:Vinyl Chloride