[Effect of synthetic hormones of the neurohypophysis on the mammary glands of sheep].
The influence of intravenous injection of various doses of synthetic oxytocin, arginine-vasopressin and lysine-vasopressin on intramammary pressure of ewes was tested. A single injection caused a short-term intramammary pressure increase. The intramammary pressure curves for the tested hormones were similar. However, big doses of oxytocin resulted in a different type of response, consisting in successive contractions of decreasing magnitude. A positive relationship between lg oxytocin doses and intramammary pressure at doses from 10 to 100 mU was shown. This relationship for arginine-vasopressin was at 200 to 500 mU, and that of lysine-vasopressin at 200 to 1 000 mU. The latency period between the moment of hormone injections and the rise in intramammary pressure decreased when bigger doses were used. The milk-ejection activity of arginine-vasopressin was only 14,5% of oxytocin activity. The activity of lysine-vasopressin was 10,2% respectively.
D000818:Animals; D001127:Arginine Vasopressin / Q000494:pharmacology; D005260:Female; D006728:Hormones / Q000494:pharmacology; D007774:Lactation / Q000187:drug effects*; D008236:Lypressin / Q000494:pharmacology; D008321:Mammary Glands, Animal / Q000378:metabolism*; D010121:Oxytocin / Q000494:pharmacology; D010909:Pituitary Hormones, Posterior / Q000494:pharmacology*; D011247:Pregnancy; D012756:Sheep / Q000502:physiology*; D013268:Stimulation, Chemical
D006728:Hormones; D010909:Pituitary Hormones, Posterior; D001127:Arginine Vasopressin; D010121:Oxytocin; D008236:Lypressin
Efekt działania syntetycznych hormonów nerwowej cześci przysadki mózgowej na gruczoł mlekowy u owcy.