[Incidence of the 9qh+ variant in subjects with occupational exposure to radiation and in cases of reproductive pathology].
The frequency of the 9qh+ variant was fond to be significantly increased (as compared to controls) in the following classes of subjects: R)professionally radioexposed individuals; P)patients with chromosomal aberrations; PP)parents of P; Cs)sterile or pluriabortive couples. While the increase of 9qh+ in P and PP individuals was already known, the findings in professionally radioexposed individuals and sterile or pluriabortive couples appear to be relatively new. Occurrence of 9qh+ might prove to be a useful indicator of chromosomal damage, while confirmation of these findings would entail stringent limitation of professional and diagnostic radioexposure.
D000026:Abortion, Habitual / Q000209:etiology*; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects*; D002906:Chromosomes, Human, 6-12 and X; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology*; D008297:Male; D011247:Pregnancy; D011830:Radiation Effects; D011831:Radiation Genetics
Incidenza della variante 9qh+ in soggetti professionalmente radioesposti ed in casi di patologia reproduttiva.