[Oncologic properties of non-inbred white rats raised at the Petrov Research Institute of the Ministry of Health of the USSR].
The paper discusses the incidence of spontaneous tumors and general morbidity in albino noninbred rats raised at the N. N. Petrov Research Institute of Oncology of the USSR Ministry of Health and used in different chronic experiments. It was found that spontaneous tumors occur, on the average, in 25.7 and malignancies--in 6.2%. Infectious hemorrhagic pneumonia and gastroenteritis (acute capillary toxicosis) are relatively infrequent. The general morbidity patterns in these rats are similar to those in Wistar line, the essential difference being a lower frequency of tumors of the medullar layer of adrenals. Hence, the rats bred at the Institute may be successfully used in various chronic experiments, including those associated with carcinogenic studies.
D000818:Animals; D009115:Muridae; D009369:Neoplasms / Q000401:mortality / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000401:mortality / Q000503:physiopathology*
Onkologicheskaia kharakteristika belykh besporodnykh krys razvodki NII onkologii im. prof. N.N. Petrova Minzdrava SSSR.