Hematoporphyrin photosensitization of epidermal microsomes results in destruction of cytochrome P-450 and in decreased monooxygenase activities and heme content.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004307:Dose-Response Relationship, Radiation; D004817:Epidermis / Q000201:enzymology / Q000528:radiation effects; D005260:Female; D006415:Hematoporphyrins / Q000633:toxicity*; D008861:Microsomes / Q000201:enzymology* / Q000528:radiation effects; D010787:Photosensitivity Disorders / Q000201:enzymology*; D011247:Pregnancy; D051381:Rats; D014466:Ultraviolet Rays
D006415:Hematoporphyrins; D003577:Cytochrome P-450 Enzyme System