title: Diurnal fluctuation in striatal choline acetyltransferase activity and strain difference in brain protein content of the rat.
abstract: Choline acetyltransferase (CAT) activity was measured in two brain regions of rat at different times of the day. A diurnal fluctuation of the CAT activity was found in the striatum with a high activity during the light period and a low activity during the dark period. In the hippocampus + cortex the CAT activity remained constant. A marked difference in the brain protein content was found between two strains of Sprague-Dawley rats. This finding emphasizes the importance of expressing enzyme activity both per g tissue and g protein especially when comparing data between different research groups.
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000378:metabolism; D002540:Cerebral Cortex / Q000201:enzymology; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D002940:Circadian Rhythm; D003342:Corpus Striatum / Q000201:enzymology; D006624:Hippocampus / Q000201:enzymology; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
chemical_list: D009419:Nerve Tissue Proteins; D002795:Choline O-Acetyltransferase