Successful chemotherapy of transfusion babesiosis.
We describe babesiosis transmitted by transfusion. The infected blood donor was identified and a minimum period of infectivity of the donor's blood was established. We report a new modality for chemotherapy consisting of quinine plus clindamycin, and a new endemic focus for this zoonosis on Fire Island, New York. There are insufficient data to establish a reasonably safe period after which visitors and residents of Babesia-endemic foci can become blood donors. Screening of such persons by a rapid serologic test, such as the ELISA or immunofluorescent antibody tests, is suggested.
D000328:Adult; D000818:Animals; D001404:Babesiosis / Q000188:drug therapy / Q000635:transmission*; D001733:Bites and Stings; D001782:Blood Donors; D002353:Carrier State; D002981:Clindamycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000635:transmission; D008297:Male; D011803:Quinine / Q000627:therapeutic use; D013987:Ticks; D013997:Time Factors; D065227:Transfusion Reaction
D002981:Clindamycin; D011803:Quinine