title: Focal giant papillary conjunctivitis from retained contact lenses.
abstract: Three cases of retained contact lenses leading to focal papillary conjunctivitis of the upper lids reminiscent of the more diffuse changes of lens or suture-induced giant papillary conjunctivitis are reported. One silicone and two cabufocon lenses were responsible. Corneal changes occurred in two of the three cases. Secondary infection with Staphylococcus aureus was found in one patient. In two, conjunctival cytology suggested a hypersensitivity mechanism. In all three patients the simple removal of the retained lens was sufficient to reverse pathology. The focal nature of the papillary changes observed in these patients as well as in those cases occurring post-operatively from exposed suture edges would point towards an important direct mechanical etiologic factor in addition to the proposed hypersensitivity basis for the similar diffuse upper lid papillary hypertrophy characteristic of giant papillary conjunctivitis.
mesh_terms: D000328:Adult; D000368:Aged; D002482:Cellulose / Q000009:adverse effects / Q000031:analogs & derivatives; D003231:Conjunctivitis / Q000209:etiology* / Q000473:pathology; D003261:Contact Lenses / Q000009:adverse effects*; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology; D005143:Eyelids / Q000473:pathology; D005260:Female; D005490:Focal Infection / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006984:Hypertrophy / Q000209:etiology; D008297:Male; D012828:Silicones / Q000009:adverse effects; D013203:Staphylococcal Infections / Q000209:etiology
chemical_list: D012828:Silicones; D002482:Cellulose; C014396:cellulose acetate-butyrate