Idiopathic hypertrophic subaortic stenosis.
IHSS is a familial illness with a significant and frequently lethal effect on cardiac function. Diagnosis can be made on clinical grounds and by echocardiography, and is confirmed by cardiac catheterization. High-dose beta -adrenergic blockade may control symptoms but does not give complete protection against fatal arrhythmias. Surgery may be required. A new class of drugs, calcium antagonists, will soon be marketed in this country and could provide more effective therapy for IHSS.
D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000517:prevention & control; D002118:Calcium / Q000037:antagonists & inhibitors; D006328:Cardiac Catheterization; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D004071:Digitalis Glycosides / Q000009:adverse effects; D004452:Echocardiography; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D011433:Propranolol / Q000627:therapeutic use; D014463:Ultrasonography; D014700:Verapamil / Q000627:therapeutic use
D004071:Digitalis Glycosides; D011433:Propranolol; D014700:Verapamil; D002118:Calcium