title: [Changes in specific and nonspecific immunity factors in saliva and serum of patients with different clinical variants of meningococcal infection].
abstract: Local and humoral immunity factors have been studied in 152 patients with different forms of meningococcal infection. The peculiar pattern of the time course of changes in these factors, depending on the clinical form of the disease, has been revealed. In the generalized form of infection changes in the immunological characteristics of the saliva and blood serum (lysozyme, secretory immunoglobulin, immunoglobulins of the main classes and specific antimeningococcal antibodies) have been shown to be more essential than in the localized form.
mesh_terms: D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008585:Meningitis, Meningococcal / Q000097:blood / Q000276:immunology; D008589:Meningococcal Infections / Q000097:blood / Q000276:immunology*; D009113:Muramidase / Q000032:analysis*; D009304:Nasopharyngitis / Q000097:blood / Q000209:etiology / Q000276:immunology*; D010612:Pharyngitis / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000276:immunology; D012463:Saliva / Q000276:immunology*; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D007136:Immunoglobulins; D011135:Polysaccharides, Bacterial; D009113:Muramidase
vernacular_title: Dinamika spetsificheskikh i nespetsificheskikh faktorov immuniteta v sliune i syvorotke krovi bol'nykh s razlichnymi klinicheskimi formami meningokokkovoi infektsii.