[Application of change-over designs in human pharmacology demonstrated by reaction-time measurements (author's transl)].
Reaction-time measurements were used to demonstrate the application of change-over designs, known as Berenblut schedules. They are especially useful when improving trial accuracy is merely possible by raising the number of test entities rather than using greater numbers of healthy subjects, which normally are not readily available.
D006801:Humans; D010600:Pharmacology / Q000379:methods*; D010634:Phenobarbital / Q000494:pharmacology; D010672:Phenytoin / Q000494:pharmacology; D011930:Reaction Time / Q000187:drug effects*; D012107:Research Design
D010672:Phenytoin; D010634:Phenobarbital
Die Anwendung balancierter Periodenversuchspläne in der Humanpharmakologie am Beispiel von Reaktionszeitmessungen.