title: Lack of specific IgE against house-dust and Dermatophagoides pteronyssinus in aspirin-sensitive asthmatics with positive skin and inhalation test.
abstract: We studied 28 atopic asthmatics with aspirin intolerance, sensitive to house dust confirmed by positive skin tests and in some patients inhalatory challenge with house dust allergen. Specific IgE against house dust and Dermatophagoides pteronyssinus was determined by RAST in all patient twice, at 6-month intervals. Only one patient presented antibodies against these allergens in serum RAST class 1.
mesh_terms: D000293:Adolescent; D000328:Adult; D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000276:immunology*; D001985:Bronchial Provocation Tests; D004342:Drug Hypersensitivity / Q000276:immunology*; D004391:Dust; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis*; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*
chemical_list: D004391:Dust; D007073:Immunoglobulin E; D001241:Aspirin