title: Intraindividual stability and extent of genetic determination of platelet monoamine oxidase activity.
abstract: Intraindividual stability and extent of genetic determination of platelet MAO activity with tryptamine as substrate was evaluated. Repeated determinations on the same days as well as during an interval of 1-30 days show a high intraindividual stability of MAO. Reexamination of subjects who had formerly been selected because of either low or high MAO activity led to a "regression to the mean", thus pointing to a certain influence of environmental factors on the enzyme values. Twin and family studies, however, show a remarkable influence of genetic factors.
mesh_terms: D001792:Blood Platelets / Q000201:enzymology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008722:Methods; D008995:Monoamine Oxidase / Q000097:blood* / Q000235:genetics; D011247:Pregnancy; D014427:Twins
chemical_list: D008995:Monoamine Oxidase