Perinatal methylmercury intoxication: behavioral effects in rats.
Sprague-Dawley rats were subjected to perinatal (4th gestational day until Postnatal Day 21) methylmercury intoxication to determine the long-term behavioral effect of the mercury poisoning. Experimental and control animals were evaluated at 110-140 days of age. Compared to controls, the methylmercury animals demonstrated significant behavioral deficits characterized by hypoactivity and by reduced appetitive, escape, and avoidance learning.
D000818:Animals; D001362:Avoidance Learning; D001835:Body Weight; D003216:Conditioning, Operant; D004644:Emotions; D005106:Exploratory Behavior; D005239:Fear; D005260:Female; D008431:Maternal-Fetal Exchange; D008767:Methylmercury Compounds / Q000506:poisoning*; D009043:Motor Activity; D011247:Pregnancy; D051381:Rats
D008767:Methylmercury Compounds; C004925:methylmercuric chloride