title: Two equine true hermaphrodites with 64,XX/64,XY and 63,XO/64,XY chimerism.
abstract: The karyotypes of a Welsh pony and a Standardbred were 64,XX/64,XY and 63,XO/64,XY respectively. Both intersexes were true hermaphrodites with bilateral ovotestes. Neither intersex showed stallion-like behaviour. Each one had an underdeveloped penis, bilateral seminal vesicles and uterine tissue. It would appear that the chimerism in these equine intersexes resulted from double fertilization or fusion of blastocysts. Mosaicism in the Standardbred is a possibility, resulting from loss of a Y chromosome by anaphase lag in an early embryonic XY cell.
mesh_terms: D000818:Animals; D002678:Chimera; D012734:Disorders of Sex Development / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000235:genetics* / Q000473:pathology; D006736:Horses / Q000235:genetics; D007621:Karyotyping / Q000662:veterinary; D008297:Male; D012729:Sex Chromosome Aberrations / Q000235:genetics / Q000662:veterinary*; D014960:X Chromosome; D014998:Y Chromosome