A clinical and immunological study of allergy to hen's egg white. III. Allergens in hen's egg white studied by crossed radio-immunoelectrophoresis (CRIE).
Allergens in hen's egg white were studied in crossed radio-immunoelectrophoresis (CRIE). Specific IgE-antibodies against different proteins in the egg white were examined in sera from 70 atopic patients with clinical hypersensitivity, and RAST greater than or equal to 2 to egg white. Ovalbumin, ovomucoid and an unidentified protein, antigen 22, were classified as major allergens. Specific IgE-antibodies against 10 more proteins in hen's egg white were detected. IgE-antibodies against lysozyme could not be detected.
D000293:Adolescent; D000485:Allergens / Q000032:analysis*; D000818:Animals; D002645:Chickens; D002648:Child; D002675:Child, Preschool; D004529:Egg White / Q000009:adverse effects*; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis; D007123:Immunoelectrophoresis, Two-Dimensional; D007223:Infant; D009113:Muramidase / Q000032:analysis; D010047:Ovalbumin / Q000032:analysis; D010059:Ovomucin / Q000032:analysis; D011817:Rabbits; D011852:Radioallergosorbent Test; D012882:Skin Tests
D000485:Allergens; D010059:Ovomucin; D010047:Ovalbumin; D009113:Muramidase