title: Computed tomography in Hallervorden-Spatz disease.
abstract: Computed tomography (CT) in a 34-year-old woman with Hallervorden-Spatz disease (established on the basis of clinicopathologic findings in a sister, and a typical clinical course) showed severe diffuse cerebral atrophy and ventricular enlargement. Ratios between the intercaudate distance and the width of the frontal horns (FH:CC) or the outer tables of the skull (CC:OTcc) exceeded those found in patients with Huntington disease. CT may be helpful diagnostically in progressive cerebral disorders of late childhood or adolescence.
mesh_terms: D000328:Adult; D001284:Atrophy; D001480:Basal Ganglia Diseases / Q000000981:diagnostic imaging*; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology; D014057:Tomography, X-Ray Computed