Thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome in HLA-identical siblings.
Thrombotic thrombocytopenic purpura and hemolytic-uremic syndrome occurred 6 1/2 years apart in HLA-identical brothers. This unique occurrence supports the concept that the two disorders may be varieties of a basic disease process and suggests the possibility of an inherited predisposition for them.
D000328:Adult; D006680:HLA Antigens; D006463:Hemolytic-Uremic Syndrome / Q000235:genetics*; D006801:Humans; D008297:Male; D011697:Purpura, Thrombotic Thrombocytopenic / Q000235:genetics*
D006680:HLA Antigens