[Comparative studies on perioperative infusion therapy in infants].
Four different infusion solutions, consisting of various amounts of sodium, potassium, chloride, phosphate and carbohydrates, were administered to infants from ten days to six months of age. The effects of these infusions on different parameters in the blood serum and on the urinary excretion were measured. It could be demonstrated that even major variations of electrolyte administration could be compensated by the infants' renal function resulting in almost constant serum parameters and adequate water balances. The administration of sodium and chloride ranged from 5-7 mmol/kg per day or from 4.44-7.55 mmol/kg per day respectively, the substitution of potassium varied between 0.25 an 2.4 mmol/kg per day and the substitution of phosphate between 0 and 0.7 mmol/kg per day. Variations of any clinical importance could only be detected for serum phosphate concentrations if phosphate-free infusion solutions had been administered. The postoperative blood glucose concentrations did not show any alterations which could be related to the glucose or glucose-xylitol contents of the infusion solutions. Following these results and according to previously reported studies in children recommendations for the sodium, potassium, chloride, phosphate and carbohydrate contents of the infusion solutions can be made as well as suggestions for the perioperative dosage of these solutions in infants and children.
D001786:Blood Glucose / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004573:Electrolytes / Q000008:administration & dosage / Q000097:blood; D005950:Glucose Solution, Hypertonic; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007263:Infusions, Parenteral / Q000379:methods*; D011182:Postoperative Care; D011300:Preoperative Care; D014994:Xylose / Q000008:administration & dosage
D001786:Blood Glucose; D004573:Electrolytes; D005950:Glucose Solution, Hypertonic; D014994:Xylose
Vergleichende Untersuchungen zur perioperativen Infusionstherapie im Säuglingsalter.