Post-transfusion purpura.
Two cases of post-transfusion purpura in multiparous women are described. Anti-PIA1 antibody was detected in both patients who subsequently recovered. This alloantibody causes the destruction of autologous platelets. The role of steroids and plasma exchange in therapy of this condition remains controversial, but they should probably be used in combination.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001792:Blood Platelets / Q000276:immunology; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000032:analysis; D008875:Middle Aged; D010956:Plasmapheresis; D010974:Platelet Aggregation; D011696:Purpura, Thrombocytopenic / Q000209:etiology* / Q000628:therapy; D065227:Transfusion Reaction; D014181:Transplantation Immunology
D000305:Adrenal Cortex Hormones; D007518:Isoantibodies