title: Plasma zinc in psoriatic in-patients treated with local zinc applications.
abstract: Zinc is a major component of many local skin applications. An investigation into its systemic absorption in thirty-one psoriatic hospital in-patients is reported. Plasma zinc, copper and whole blood delta-aminolaevulinic acid dehydratase were followed before and during in-patient treatment over 14 days. No significant alteration in these parameters was detected. Significantly reduced plasma zinc levels were found in the patients compared to a matched control population.
mesh_terms: D000287:Administration, Topical; D002940:Circadian Rhythm; D003300:Copper / Q000097:blood; D004339:Drug Compounding; D006801:Humans; D007854:Lead / Q000097:blood; D000623:Porphobilinogen Synthase / Q000097:blood; D011565:Psoriasis / Q000097:blood* / Q000188:drug therapy / Q000201:enzymology; D015032:Zinc / Q000008:administration & dosage / Q000097:blood*
chemical_list: D007854:Lead; D003300:Copper; D000623:Porphobilinogen Synthase; D015032:Zinc