Chronic administration of chloramphenicol, a protein synthesis inhibitor, selectively decreases REM sleep.
D000818:Animals; D002415:Cats; D002701:Chloramphenicol / Q000494:pharmacology*; D006801:Humans; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors*; D012895:Sleep, REM / Q000187:drug effects*; D013375:Substance Withdrawal Syndrome / Q000523:psychology
D009419:Nerve Tissue Proteins; D002701:Chloramphenicol