Human intracranial tumors: effect of autologous serum addition on leucocyte migration inhibition.
42 human intracranial tumours were investigated by the leucocyte migration inhibition technique at various antigen concentration with and without autologous serum addition. A correlation was found between migration rate and antigen concentration. Autologous serum addition resulted in a non-specific stimulation of migration, however, stimulation by immune complexes was also present. Migration stimulation, as an in-vitro-equivalent of immunologic tumor enhancement, is discussed.
D000951:Antigens, Neoplasm / Q000276:immunology*; D001254:Astrocytoma / Q000276:immunology; D001798:Blood Proteins / Q000276:immunology*; D001932:Brain Neoplasms / Q000276:immunology*; D002464:Cell Migration Inhibition; D005910:Glioma / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology*; D008577:Meningeal Neoplasms / Q000276:immunology; D008579:Meningioma / Q000276:immunology; D012509:Sarcoma / Q000276:immunology
D000951:Antigens, Neoplasm; D001798:Blood Proteins