A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins.
The complexing of furocoumarins with DNA in aqueous solution has been investigated using the fast-reaction technique of pulse radiolysis. Association constants are given for 8-methoxypsoralen, psoralen, khellin, angelicin, 5,7-dimethoxycoumarin, 5-methoxypsoralen and 4'-aminomethyl-4,5',8-trimethylpsoralen. In addition, the complexing of some furocoumarins to the protein, bovine serum albumin, has also been studied.
D000818:Animals; D001665:Binding Sites; D002417:Cattle; D004247:DNA; D011564:Furocoumarins; D007700:Kinetics; D010315:Particle Accelerators; D011485:Protein Binding; D012710:Serum Albumin, Bovine; D013329:Structure-Activity Relationship; D013950:Thymus Gland
D011564:Furocoumarins; D012710:Serum Albumin, Bovine; D004247:DNA