[Phenogenetic analysis of recessive epistasis of the or gene over the Bld gene in mice].
Results concerning interaction between the genes blind (Bld) and ocular retardation (or) during mouse embryogenesis are presented. It was established that in Bld/+ or/or mice the Bld gene effects are not expressed, as a result of the pronounced eye reduction caused by the or gene action. In Bld/+ or/or embryos the phenocritic stage of the Bld gene action is deplaced to more early embryogenesis period than that in the Bld/+ +/+ embryos. This leads to the recessive epistasis of the or gene over the Bld gene. The analysis of gene interaction has also indicated that the lid mesodermal component growth is the primary target process affected by the Bld/+ constitution.
D000818:Animals; D003433:Crosses, Genetic; D004843:Epistasis, Genetic; D005123:Eye / Q000196:embryology; D005143:Eyelids / Q000201:enzymology; D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D006720:Homozygote; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D010641:Phenotype
Fenogeneticheskiĭ analiz retsessivnogo épistaza gena or nad genom Bld u myshi.