title: Neonatal decortication and adult female sexual behavior.
abstract: Neonatal lesions of the cerebral cortex in female rats did not eliminate female sexual behavior as measured by lordosis. However, lordosis in response to prolonged low levels of estradiol benzoate (1.0 micrograms/day for 6 days) was attenuated in lesioned females. Following estradiol benzoate plus progesterone (0.5 mg) treatment the probability of lordosis increased markedly in the decorticate females, but still remained below control levels. Decorticate females were mounted by the male at least as often as control females. Hopping and darting and rejection behaviors on the part of the female were virtually eliminated in the decorticate group. However, these females continued to direct sniffing behavior toward the male at levels above those of the controls.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002369:Castration; D002540:Cerebral Cortex / Q000502:physiology*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D009115:Muridae; D011374:Progesterone / Q000494:pharmacology; D012726:Sexual Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D012919:Social Behavior
chemical_list: D011374:Progesterone; D004958:Estradiol