title: Routine focal mollusciciding after chemotherapy to control Schistosoma mansoni in Cul de Sac valley, Saint Lucia.
abstract: Concluding results of a 10-year schistosomiasis control programme in Cul de Sac valley, Saint Lucia, are described. After an area-wide mollusciciding campaign (1970-75), and a surveillance/treatment programme supplemented with selective population chemotherapy in 1975 and 1976, prevalence rates of Schistosoma mansoni were reduced to low levels. To prevent a resurgence of transmission a cost effective routine focal mollusciciding programme, suitable for public health implementation was evaluated from 1977 to 1981. Streams and main collector drains in banana fields, considered to be potential S. mansoni transmission sites, were treated every four weeks with Bayluscide 6076 emulsifiable concentrate (Clonitralide). Snail populations were effectively controlled in the treated areas but large numbers were present where no treatment was given. Only 0 X 06% of sentinel snails became infected. Prevalence of infection in the human population remained low (over-all 5%) and intensity of infection at a level not normally associated with schistosomal disease. Since control started 10 years earlier the level of potential contamination has fallen by 92% in high transmission areas. The four-year programme cost US+12,909 of which 54% was for molluscicide, 27% for labour and 19% for transport, equipment and sundries. The average annual cost per head of population was US+0 X 46.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001700:Biomphalaria; D002648:Child; D002675:Child, Preschool; D003365:Costs and Cost Analysis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D008975:Molluscacides; D009534:Niclosamide / Q000031:analogs & derivatives*; D010571:Pest Control / Q000191:economics / Q000379:methods*; D012499:Sanitation; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D014881:Water Supply; D014900:West Indies
chemical_list: D008975:Molluscacides; D009534:Niclosamide