Proliferative activity of capillary wall cells in skeletal muscle of rats during long-term treatment with dipyridamole.
Cellular proliferation in skeletal muscle of Sprague-Dawley rats studied by incorporation of 3H-thymidine during administration of dipyridamole (Persantin). The proliferative activity was restricted to capillary wall cells, and the increase during dipyridamole treatment was highly significant (p less than 0.0005).
D000375:Aging; D000818:Animals; D001345:Autoradiography; D001835:Body Weight / Q000187:drug effects; D002196:Capillaries / Q000166:cytology / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis; D004176:Dipyridamole / Q000494:pharmacology*; D005260:Female; D008297:Male; D009132:Muscles / Q000098:blood supply*; D051381:Rats; D012039:Regional Blood Flow / Q000187:drug effects
D004176:Dipyridamole; D004247:DNA