[Value of deliberate normovolemic hemodilution associated with a capillary vasoconstrictor, ornipressin, in surgery of the spine].
This study of sixty-seven children divided in two groups compared the blood loss and the amount of blood transfused during and after the operation. The operations were carried out without haemodilution nor the local injection of vasoconstrictor (twenty-four patients) and following haemodilution and the local injection of vasoconstrictor (forty-three patients). The blood loss during operation was 344 +/- 455 ml per vertebra in the first group, and 151 +/- 54 ml in the second. The blood loss in the post operative period did not seem to be modified by haemodilution, as the level of hemoglobulin was virtually the same in the two groups eleven days after the operation. A mean of seven units of blood were transfused to the first group, whilst only three in the second group. In the post-operative period, both groups received a mean of one unit each. Associating haemodilution and a vasoconstrictor, ornipressin, reduced very significantly the need for homologous blood.
D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D002648:Child; D005260:Female; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D008297:Male; D009951:Ornipressin / Q000008:administration & dosage*; D011184:Postoperative Period; D013123:Spinal Fusion; D014667:Vasopressins / Q000008:administration & dosage*
D014667:Vasopressins; D009951:Ornipressin
Intérêt de l'hémodilution normovolémique intentionnelle associée à un vaso-constricteur capillaire, l'ornipressine, dans la chirurgie du rachis.