title: Apparent inactivity of several antiparasitic compounds against the eyeworm Thelazia lacrymalis in equids.
abstract: Activity of 15 compounds, given alone or in mixtures [butamisole, cambendazole, caviphos, febantel (alone or with trichlorfon), fenbendazole, ivermectin, levamisole-piperazine, oxfendazole, oxibendazole, pyrantel pamoate (alone or with piperazine-carbon disulfide complex), thiabendazole (alone or with piperazine or with trichlorfon), tioxidazole, and trichlorfon], against Thelazia lacrymalis was evaluated in 102 equids. Determination of activity was based on comparison of infection rate in treated animals examined at necropsy with infection rate of dead equids in our contemporary surveys. None of the compounds appeared to be active against T lacrymalis.
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology; D006736:Horses / Q000469:parasitology; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D013151:Spiruroidea / Q000187:drug effects*; D013802:Thelazioidea / Q000187:drug effects*
chemical_list: D000969:Antinematodal Agents