[LDH isoenzyme spectrum of the extramural ganglia of the autonomic nervous system, the working heart, and cardiac conduction system of rabbits during acute experimental emotional stress].
The content of LDH isozymes was studied in extramural ganglions (superior cervical ganglion, stellate ganglion and symphathetic chain at the level of the 4th--6th thoracic segments) of the sympathetic nervous system, of the nodosal ganglion of the vagus nerve, working myocardium and conductive system of the heart of rabbits with acute experimental emotional stress provoked by simultaneous electric stimulation of the negative emotiogenic area of the hypothalamus, ventromedial nuclei, and skin. Under conditions of emotional stress no changes could be recorded in the ratio of LDH isozymic fractions in the ganglions as compared with control. No changes were found in LDH content of the working myocardium in rabbits exposed to stress. The conductive system of the heart (atrioventricular node and His' bundle) demonstrated a certain sensitivity to stress, manifesting in the increased activity of fast-moving fractions in the spectrum of LDH isozymes. The modulated electromagnetic field that exerts a protective action against an adverse effect of emotional stress produced significant shifts in LDH spectrum in the ganglions of the autonomous nervous system. No changes were detected in the spectrum of LDH isozymes in the conductive system. The results obtained suggest that the above structures of the autonomous nervous system are an important link in the bodily response to the concomitant action of the two stressors.
D000208:Acute Disease; D000818:Animals; D005725:Ganglia, Autonomic / Q000201:enzymology*; D005728:Ganglia, Sympathetic / Q000201:enzymology; D006321:Heart / Q000294:innervation*; D006329:Heart Conduction System / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D009206:Myocardium / Q000201:enzymology*; D009620:Nodose Ganglion / Q000201:enzymology; D011817:Rabbits; D013233:Stellate Ganglion / Q000201:enzymology; D013315:Stress, Psychological / Q000201:enzymology*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Spektr izofermentov LDG ékstramural'nykh uzlov avtonomnoĭ nervnoĭ sistemy, rabochego miokarda i provodiashcheĭ sistemy serdtsa krolika pri ostrom éksperimental'nom émotsional'nom stresse.