title: Red blood cell susceptibility to hydrogen peroxide (H2O2) lysis in chronic hemodialysis patients.
abstract: To assess susceptibility to oxidant induced membrane damage, the red blood cell H2O2 hemolysis test was performed in fifty-three chronic hemodialysis patients. Uremic red blood cells were not more susceptible to 2.5% H2O2 lysis pre or postdialysis than were control red blood cells. Oxidant induced red blood cell lysis is a function of the strength of the oxidant and not a testable intrinsic defect of the uremic red blood cell.
mesh_terms: D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D006861:Hydrogen Peroxide; D066298:In Vitro Techniques; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy; D006435:Renal Dialysis
chemical_list: D006861:Hydrogen Peroxide