[Cocarcinogen as a factor increasing the incidence of mutation responsible for cellular resistance to antifolates].
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003043:Cocarcinogenesis; D004351:Drug Resistance; D005796:Genes; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D051379:Mice; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology*; D010704:Phorbols / Q000009:adverse effects*; D013755:Tetradecanoylphorbol Acetate / Q000009:adverse effects*; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics
D010704:Phorbols; D013762:Tetrahydrofolate Dehydrogenase; D013755:Tetradecanoylphorbol Acetate; D008727:Methotrexate
Kokancerogen jako czynnik zwiekszajacy czestotliwość mutacji odpowiedzialnej za odporność komórek na antyfoliany.