title: The effect of long-term HCG or TP administration on reproductive functions in adult male rabbits. I. Histomorphological changes in the scrotum.
abstract: The effect of long-term treatment with various doses of HCG or TP on the scrotum was studied in 36 adult rabbits of pure Bouscat breed. The epidermis of the scrotum exhibited a more significant dose-related increase in thickness in animals injected with TP than those treated with HCG. The hair follicles in animals injected with higher doses of HCG or TP were thicker in diameter and extended deeper within the dermis where they curved to grow parallel to the surface of the skin. The high dose of HCG was more effective in demonstrating higher glandular activity than that seen in rabbits treated with high doses of TP. The vascularization in the scrotum was more prominent in rabbits treated with higher doses of HCG. The fibers of the Tunica dartos were much thicker in animals treated with high doses of HCG or TP.
mesh_terms: D000818:Animals; D001485:Basement Membrane / Q000187:drug effects; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008297:Male; D011817:Rabbits; D012098:Reproduction / Q000187:drug effects*; D012611:Scrotum / Q000187:drug effects*; D012867:Skin / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D006063:Chorionic Gonadotropin; D013739:Testosterone