Vascular effects of vasopressin an oxytocin in the pig mesenteric bed.
The influence of intraarterial infusions of lysine-vasopressin and oxytocin on mesenteric vascular resistance has been studied in anaesthetized young pigs. Vasopressin provokes a pronounced vasoconstrictor effect, whereas oxytocin induces a biphasic response: a transient vasodilation, followed by a more pronounced and sustained vasoconstriction. The comparison of the plasma concentrations of these hormones during parturition and hemorrhage in the pig with the minimal effective doses infused, suggests a possible mesenteric vasoconstrictor effect of oxytocin during parturition and of lysine-vasopressin during hemorrhage.
D000818:Animals; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D007261:Infusions, Intra-Arterial; D007743:Labor, Obstetric / Q000187:drug effects; D008236:Lypressin / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D010121:Oxytocin / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy; D013152:Splanchnic Circulation / Q000187:drug effects*; D013552:Swine; D014655:Vascular Resistance / Q000187:drug effects; D014661:Vasoconstriction / Q000187:drug effects; D014664:Vasodilation / Q000187:drug effects
D010121:Oxytocin; D008236:Lypressin