title: Nerve conduction studies in patients treated with cis-diamminedichloroplatinum(II): a preliminary report.
abstract: We performed serial histories, physical examinations, and nerve conduction studies on seven cancer patients who were treated with cis-diamminedichloroplatinum(II). Total cumulative doses ranged from 200 to 350 mg/m2. In nerve conduction studies, three of seven patients showed subclinical, predominantly sensory, changes compatible with a peripheral neuropathy.
mesh_terms: D000328:Adult; D002945:Cisplatin / Q000494:pharmacology*; D006801:Humans; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects*; D010525:Peripheral Nerves / Q000187:drug effects
chemical_list: D002945:Cisplatin