Microbial transformations of natural antitumor agents. 13. Conversions of 13-blocked anthracyclinones.
Microbial transformation experiments were performed using 13-ketone-blocked daunomycinone derivatives which were converted into the corresponding carminomycinone derivatives by microbial O-demethylation.
D000903:Antibiotics, Antineoplastic / Q000378:metabolism*; D002360:Carubicin / Q000031:analogs & derivatives / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D003630:Daunorubicin; D005285:Fermentation; D003904:Mitosporic Fungi / Q000378:metabolism; D009279:Naphthacenes / Q000378:metabolism*
D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; C015736:carminomycinone; D002360:Carubicin; C019318:daunomycinone; D003630:Daunorubicin