title: Genetic polymorphism of C3 in Papio and Macaca species.
abstract: C3 phenotypes were examined in species of Papio and Macaca. Baboons (P. cynocephalus) showed extensive polymorphism, with estimated gene frequencies of 0.815, 0.174, and 0.011 for C3*S, C3*F, and C3*F1 alleles, respectively. Clear segregation patterns showing codominant inheritance were evident in family studies. Such extensive polymorphism was not observed in M. nemestrina or M. fascicularis. The S gene is the most common allele in all the species studied. The F gene is relatively common in baboons.
mesh_terms: D000818:Animals; D003176:Complement C3 / Q000235:genetics*; D006579:Heterozygote; D008251:Macaca / Q000235:genetics*; D010215:Papio / Q000235:genetics*; D010375:Pedigree; D011110:Polymorphism, Genetic
chemical_list: D003176:Complement C3