Improved NMR contrast for mouse mammary cancer by safe physiological agents.
Common safe physiological agents such as diuretics, hormones, and oral lipids can increase differences in NMR parameters between uninvolved breast tissue in tumor bearing animals and mammary carcinomas. The differential response of the normal tissue to such agents, and the relative unresponsiveness of tumors, increased NMR distinction by as much as 250%.
D000818:Animals; D002996:Clomiphene / Q000494:pharmacology; D005260:Female; D005665:Furosemide / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000502:physiology; D008325:Mammary Neoplasms, Experimental / Q000503:physiopathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy
D002996:Clomiphene; D005665:Furosemide