Amyloidosis of the stomach. Report of a case with ultrastructure.
The author reports on a rare case of local amyloidosis (amyloid tumour) of the stomach. The first electron-microscopic study of such case was performed by her. She observed a large number of microfilaments in the mucus producing cells of the stomach mucosa, and assumed this to be indicative of a pathologic mucus secretion. The epithelial cells involved also changes indicating the disorder of protein secretion. She treats in detail the electron-microscopic characteristics of cellular elements found in amyloid. The closest relationship to amyloid deposits was shown by myofibroblasts. They probably play an important role in the formation of local amyloid.
D000368:Aged; D000686:Amyloidosis / Q000473:pathology*; D003599:Cytoskeleton / Q000648:ultrastructure; D005347:Fibroblasts / Q000648:ultrastructure; D005753:Gastric Mucosa / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D013272:Stomach Diseases / Q000473:pathology*