Effects of hypophysectomy and of LH administration on luteal phase plasma progesterone levels in the beagle bitch.
Luteal-phase progesterone levels in 5 beagle bitches fell to 0.3-0.4 ng/ml within 3-17 days after hypophysectomies on Day 10-50 of the cycle. Plasma progesterone in 6 bitches increased (P < 0.01) within 3 h after LH (100 microgram/kg) injection between Days 35 and 55 of the cycle. Normal luteal function in the bitch appears to require continuous pituitary trophic support perhaps involving LH.
D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects / Q000502:physiology*; D004285:Dogs; D005260:Female; D007016:Hypophysectomy; D007986:Luteinizing Hormone / Q000494:pharmacology*; D011247:Pregnancy; D011359:Proestrus; D011374:Progesterone / Q000097:blood*
D011374:Progesterone; D007986:Luteinizing Hormone