Serotonin concentrations in brain and blood of scrapie-infected and normal hamsters and mice.
Whole brains and bloods of scrapie-infected and control mice and hamsters were assayed for serotonin content. Late clinical scrapie-infected mice showed a 20% reduction in whole-brain serotonin concentrations but no change in blood concentrations relative to controls. Late clinical scrapie-infected hamsters showed no change in whole-brain serotonin concentrations but a 2.5-fold decrease in blood concentrations relative to controls.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D006224:Cricetinae; D005260:Female; D008647:Mesocricetus; D051379:Mice; D012016:Reference Values; D012608:Scrapie / Q000378:metabolism*; D012701:Serotonin / Q000097:blood / Q000378:metabolism*; D012756:Sheep
D012701:Serotonin