title: Malignant granular cell tumour (myoblastoma) of the vulva: report of a case and review of the literature.
abstract: A case of malignant granular cell tumour (myoblastoma) which metastasized from the vulva to the regional lymph nodes is presented. Electron microscopy of the metastases demonstrated the presence of numerous intra-cytoplasmic lysosomes, a feature characteristic of these neoplasms, and the neoplasm was shown to stain strongly for carcinoembryonic antigen (CEA) using the immunoperoxidase technique. Previous reports in the literature of malignant granular cell tumours are reviewed and discussed.
mesh_terms: D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008247:Lysosomes / Q000648:ultrastructure; D008854:Microscopy, Electron; D011247:Pregnancy; D011248:Pregnancy Complications; D012509:Sarcoma / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D014846:Vulvar Neoplasms / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure
chemical_list: D002272:Carcinoembryonic Antigen