The action of S-adenosyl-L-methionine on the levels of triglyceride and phospholipid precursors in ethanol-intoxicated rat liver.
Acute ethanol intoxication (7 g/kg body wt) produces modifications of rat liver lipid metabolism. The effect of S-adenosyl-L-methionine (SAM) on hepatic triglyceride accumulation and on some hydrosoluble phospholipid precursors (phosphorylcholine, phosphorylethanolamine, CDP-choline, CDP-ethanolamine) has been examined in this work. The administration of SAM improves the removal of triacylglycerol from ethanol-intoxicated livers and produces modifications of the pools of some hydrosoluble phospholipid precursors.
D000435:Alcoholic Intoxication / Q000378:metabolism*; D000818:Animals; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012436:S-Adenosylmethionine / Q000494:pharmacology*; D014280:Triglycerides / Q000378:metabolism*
D010743:Phospholipids; D014280:Triglycerides; D012436:S-Adenosylmethionine