Prolonged survival after cerebral metastasis of testicular carcinoma.
A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotomy a large mass of choriocarcinomatous tissue was incompletely removed. Further chemotherapy resulted in a complete remission. The patient remains free of disease more than 16 years later. The treatment of cerebral metastasis is discussed, with emphasis on the possibility of long-term survival and the role of surgery.
D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary*; D002822:Choriocarcinoma / Q000473:pathology / Q000556:secondary*; D004407:Dysgerminoma / Q000473:pathology*; D006801:Humans; D008297:Male; D011379:Prognosis; D013724:Teratoma / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*