title: Tradescantia assay system for gaseous mutagens. A report of the U.S. Environmental Protection Agency Gene-Tox Program.
abstract: The hybrid diploid clone 4430- of the plant Tradescantia is heterozygous for a flower color locus. Its blue phenotype is the product of the dominant blue allele, and its pink phenotype is controlled by a recessive pink allele unmasked by mutation or deletion of the blue allele. Somatic cell mutants in the filamentous stamen hair are scored to measure mutagenic effect. The plant is used for tests conducted in the field and laboratory alike, and it is uniquely suited for the detection of gaseous mutagens.
mesh_terms: D002453:Cell Cycle; D004305:Dose-Response Relationship, Drug; D005740:Gases; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology; D010858:Pigmentation; D010944:Plants / Q000235:genetics*; D013997:Time Factors
chemical_list: D005740:Gases; D009153:Mutagens