title: Ethanol-Metrecal diets: I. effects of different levels of ethanol-derived kilocalories on consumption of diet, body weight and grams of ethanol ingested.
abstract: Three experiments investigated the relationship between ethanol consumption and the percentage of ethanol-derived kilocalories contained in liquid diets. Rats were chronically maintained on diets where different concentrations of ethanol (10%, 12%, 14%) were added to Metrecal so that 41%, 49% and 57% of all kilocalories consumed were derived from ethanol. The ethanol-Metrecal diet served as the sole source of calories. Results demonstrated that rats can be maintained for extended time periods on diets where ethanol contributed approximately 50% of the daily kilocalories. Inspection of consummatory profiles revealed that an initial decrease occurred in volume of diet consumed when levels of ethanol were increased. This was followed by a gradual increase in the level of consumption until a new asymptotic level was established. Grams of ethanol/kg of body weight remained relatively constant over the range of ethanol concentrations employed. The results were discussed in respect to three factors controlling consummatory behavior--sensory stimuli, caloric intake and quantity of ethanol ingested.
mesh_terms: D000161:Acoustic Stimulation; D000428:Alcohol Drinking; D000437:Alcoholism / Q000523:psychology; D000818:Animals; D001522:Behavior, Animal; D001835:Body Weight; D004032:Diet; D002149:Energy Intake; D000431:Ethanol / Q000097:blood; D005247:Feeding Behavior; D005260:Female; D005526:Food, Formulated; D006801:Humans; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000175:diagnosis
chemical_list: D000431:Ethanol