title: Effect on the incidence of atrophic rhinitis of vaccination of sows with a vaccine containing Pasteurella multocida toxin.
abstract: Combined experimental infections with Bordetella bronchiseptica and either a toxigenic or a non-toxic strain of P. multocida were carried out in newborn specific pathogen free piglets born to 25 sows. Pigs inoculated with B. bronchiseptica and toxin-producing P. multocida developed severe progressive atrophic rhinitis corresponding to the natural disease. The effect of vaccination of sows with a toxin-containing P. multocida vaccine on the incidence of nasal lesions in the offspring was studied.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology; D001284:Atrophy; D001427:Bacterial Toxins / Q000276:immunology*; D001428:Bacterial Vaccines / Q000276:immunology*; D001885:Bordetella Infections / Q000517:prevention & control / Q000662:veterinary*; D005260:Female; D010325:Pasteurella / Q000276:immunology*; D010326:Pasteurella Infections / Q000517:prevention & control / Q000662:veterinary*; D011247:Pregnancy; D012222:Rhinitis, Atrophic / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000209:etiology / Q000517:prevention & control*; D014420:Turbinates / Q000473:pathology; D014611:Vaccination / Q000662:veterinary*
chemical_list: D001427:Bacterial Toxins; D001428:Bacterial Vaccines