On the cytoprotective action of sulfhydryl-containing substances.
Sulfhydryl substances (cysteine, glutathione, cysteamine and BAL) provide protection against experimental gastric ulcer induced by indomethacin while being ulcerogenous in stress-ulcer. Experimental data indicate the necessity to distinguish between "real" and "occasional" cytoprotective drugs.
D000818:Animals; D003543:Cysteamine / Q000494:pharmacology*; D003545:Cysteine / Q000494:pharmacology*; D004112:Dimercaprol / Q000494:pharmacology*; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects*; D005978:Glutathione / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000517:prevention & control*; D013312:Stress, Physiological
D004112:Dimercaprol; D003543:Cysteamine; D005978:Glutathione; D003545:Cysteine