[Myocardial DNA damage and repair in emotional-painful stress].
[Partial depolymerization of myocardial DNA was found to ensue within the first hours after termination of stress exposure. The depolymerization was accompanied by DNA synthesis repair manifesting both in in-vivo and in-vitro experiments. With time the repair of DNA synthesis decreased while its polymerism got recovered. The data obtained provide evidence in favour of the relationship between the stress-induced free radical activation and damage and subsequent DNA synthesis repair.
D000818:Animals; D004247:DNA / Q000378:metabolism*; D004260:DNA Repair; D006801:Humans; D009206:Myocardium / Q000378:metabolism*; D010146:Pain / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000378:metabolism*; D013942:Thymine Nucleotides / Q000378:metabolism
D013942:Thymine Nucleotides; D004247:DNA; C024157:thymidine 5'-triphosphate
Povrezhdenie i reparatsiia DNK serdechnoĭ myshtsy pri émotsional'no-bolevom stresse.