Eosinophilia of obscure aetiology study of antigenic properties.
A case with a high eosinophilic leukocyte count (100 000/microliter) gradually decreasing to normal in the course of three weeks without any treatment is presented. The highly purified suspension of eosinophilic leukocytes (96 per cent of cells) separated from the peripheral blood following sedimentation with dextran and subsequent centrifugation on 1.148 g/ml density Verografin solution allowed to perform some assays of the presence of membrane antigens. In the complement-mediated cytotoxic reaction using anti T, anti Ia-like and anti AML xenosera we failed to find T, Ia-like antigens and leukaemic antigens on the purified eosinophilic leukocytes.
D000328:Adult; D000954:Antigens, Surface / Q000032:analysis*; D003602:Cytotoxicity, Immunologic; D004802:Eosinophilia / Q000209:etiology / Q000276:immunology*; D004804:Eosinophils / Q000276:immunology*; D006801:Humans; D007958:Leukocyte Count; D008297:Male
D000954:Antigens, Surface