Comparative stability of newly introduced beta-lactam antibiotics to renal dipeptidase.
Renal dipeptidase purified from swine kidney hydrolyzed N-formimidoyl thienamycin, carpetimycins A and B, and Sch29482, but not azthreonam, penicillin G, or cephaloridine.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D004150:Dipeptidases / Q000378:metabolism*; D006868:Hydrolysis; D066298:In Vitro Techniques; D007668:Kidney / Q000201:enzymology*; D007700:Kinetics; D013552:Swine; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D004150:Dipeptidases