title: Crystalline actin tubes. V. The effect of Th4+ on actin and the role of ionic charge in tube formation.
abstract: NMR and UV spectroscopy reveal that the tetravalent thorium ion interacts with actin in an identical fashion to the trivalent lanthanide ions. UV spectra and viscometry data suggest that the actin-bound Th4+ has an ionic radius of about 110 pm. Th4+ also contributes to the formation of crystalline actin tubes under appropriate conditions. The factors governing whether tubes form appear to be cationic radius and total charge on the actin monomer, rather than the valency of the ion per se.
mesh_terms: D000199:Actins; D000818:Animals; D002412:Cations; D003460:Crystallization; D004563:Electrochemistry; D009682:Magnetic Resonance Spectroscopy; D008674:Metals, Rare Earth; D008854:Microscopy, Electron; D011817:Rabbits; D013056:Spectrophotometry, Ultraviolet; D013552:Swine; D013910:Thorium; D014783:Viscosity
chemical_list: D000199:Actins; D002412:Cations; D008674:Metals, Rare Earth; D013910:Thorium