Modification of in vivo methotrexate antitumor effect in L1210 leukemia by induced impairment of purine salvage.
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004351:Drug Resistance; D007939:Leukemia L1210 / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D015122:Mercaptopurine / Q000494:pharmacology; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D009154:Mutation; D011687:Purines / Q000378:metabolism*; D013936:Thymidine / Q000494:pharmacology
D011687:Purines; D015122:Mercaptopurine; D013936:Thymidine; D008727:Methotrexate