Haemodynamic changes in essential hypertension in young subjects.
The haemodynamic changes in essential hypertension were investigated in 7 girls and 4 boys under the age of 18 years. The Fick method was used for the estimation of cardiac output (CO). The cardiac indices (CIs) ranged form 2.8 to 6.6 litres/min/m2 and the total peripheral resistance (TPR) from 1,100 to 2,860 dyn/s/cm-5 X m2. Comparison of the results with normal values reported earlier showed that the CIs in the present series were increased in 2 patients and normal in the others. The stroke volume was increased in 3 patients. TPR was elevated in 4 patients. It is proposed that essential hypertension does not always begin with an increase in CO, and that some forms of essential hypertensions can have a high TPR already at the onset of the disease.
D000293:Adolescent; D001794:Blood Pressure; D002302:Cardiac Output; D002648:Child; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption; D014655:Vascular Resistance