Nucleolar specific acidic phosphoprotein C23 is highly methylated.
Protein C23 (Mr = 110,000; pI, 5.5) is the major phosphoprotein in the nucleolus of Novikoff hepatoma cells and comprises 9.5% of the total nucleolar protein. In addition to being highly phosphorylated (1.2 mol % of phosphoserine), it is also highly methylated. Protein C23 contains 1.3 mol % of NG,NG-dimethylarginine and a trace of NG-monomethylarginine.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives / Q000032:analysis; D002466:Cell Nucleolus / Q000032:analysis*; D008114:Liver Neoplasms, Experimental / Q000032:analysis*; D008745:Methylation; D008970:Molecular Weight; D010750:Phosphoproteins / Q000302:isolation & purification*; D051381:Rats
D000596:Amino Acids; D010750:Phosphoproteins; C036825:phosphoprotein C23; C024917:symmetric dimethylarginine; C012427:2-methylarginine; D001120:Arginine