title: Adhesion, phagocytosis and cell surface energy. The binding of fixed human erythrocytes to rat macrophages and polymethylpentene.
abstract: Fixed human erythrocytes were used as model particles for the study of adhesion and phagocytosis by rat peritoneal macrophages. Erythrocytes were fixed with various concentrations of glutaraldehyde or tannic acid, or were treated with neuraminidase. Adhesion and phagocytosis of these cells were measured. In addition, the surface energy of these erythrocytes and macrophages was estimated by the contact angle technique. Free energies of adhesion, based on the cell surface energies, were correlated with both adhesion and phagocytosis.
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002462:Cell Membrane / Q000502:physiology; D004912:Erythrocytes / Q000502:physiology*; D005404:Fixatives / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D008264:Macrophages / Q000502:physiology*; D009439:Neuraminidase / Q000494:pharmacology; D010587:Phagocytosis / Q000187:drug effects; D011090:Polyenes / Q000378:metabolism; D051381:Rats; D013816:Thermodynamics
chemical_list: D005404:Fixatives; D011090:Polyenes; C021245:poly(methylpentene); D009439:Neuraminidase