Tumor rejection in rats after inescapable or escapable shock.
Rats experienced inescapable, escapable, or no electric shock 1 day after being implanted with a Walker 256 tumor preparation. Only 27 percent of the rats receiving inescapable shock rejected the tumor, whereas 63 percent of the rats receiving escapable shock and 54 percent of the rats receiving no shock rejected the tumor. These results imply that lack of control over stressors reduces tumor rejection and decreases survival.
D000818:Animals; D002279:Carcinoma 256, Walker / Q000276:immunology*; D006084:Graft Rejection; D006801:Humans; D051381:Rats; D013315:Stress, Psychological / Q000150:complications* / Q000276:immunology