title: [Adult respiratory distress syndrome (ARDS) after poisoning by local anesthetics].
abstract: Two children who received an overdose of nupercaine (cinchocainium chloratum) showed severe neurological and cardiovascular disturbances and developed adult respiratory distress syndrome (ARDS). Following initial cardiovascular resuscitation they underwent invasive neurointensive care and required controlled ventilation for a period of 6-15 days, initially with high positive end expiratory pressure (PEEP) for treatment of the ARDS. However, both survived and made a complete recovery.
mesh_terms: D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002675:Child, Preschool; D003992:Dibucaine / Q000506:poisoning*; D005260:Female; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects; D008012:Lidocaine / Q000627:therapeutic use; D008478:Mediastinal Emphysema / Q000139:chemically induced; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000139:chemically induced* / Q000628:therapy; D012151:Resuscitation; D012640:Seizures / Q000139:chemically induced; D012770:Shock, Cardiogenic / Q000139:chemically induced; D014693:Ventricular Fibrillation / Q000139:chemically induced
chemical_list: D008012:Lidocaine; D003992:Dibucaine
vernacular_title: Adult Respiratory Distress Syndrome (ARDS) nach Intoxikation durch Lokalanästhetika.