title: Effects of exposure to cold and catecholamines on the respiratory quotient and plasma levels of free fatty acids, glucose and urea in rats acclimated to 15 degrees C.
abstract: The reported experiments were carried out on 95 male Wistar rats weighing 300 to 360 g kept for 3 weeks in separate cages in a room at an ambient temperature of 15 degrees C. The rats normally fed or fasted for 24 hours were injected at 24-26 degrees C with adrenaline or noradrenaline (400 micrograms/kg s.c.) or injected at 15 degrees C with propranolol (1 mg/kg s.c.). The metabolic rate (MR), respiratory quotient (RQ) and plasma levels of free fatty acids (FFA), glucose (G) and urea (U) were determined. Similarly as in the non-acclimated rats, the determined parameters considered separately were insufficient for estimating the changes in the catabolism of lipids, carbohydrates and proteins, but a simultaneous determination of the RQ and plasma levels of FFA, G or U with MR measurement indicated the degree of lipid, carbohydrate or protein participation in cold-induced thermogenesis.
mesh_terms: D000064:Acclimatization; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D003080:Cold Temperature; D004837:Epinephrine / Q000494:pharmacology*; D005215:Fasting; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012119:Respiration / Q000187:drug effects*; D014508:Urea / Q000097:blood*
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D014508:Urea; D011433:Propranolol; D009638:Norepinephrine; D004837:Epinephrine