title: DNA and its precursors might interact with the food preservatives, sodium sulphite and sodium benzoate.
abstract: The interaction of sodium sulphite and sodium benzoate with nucleosides and DNA has been studied in vitro. Reduction in UV-absorbance was consistently noticed. However, no new products result from such interaction. It is likely that our previous observations of the effects of the 2 food preservatives on DNA synthesis and mitotis in Vicia faba root meristems is not due to direct action of the chemicals at the level of genetic material.
mesh_terms: D000241:Adenosine; D000818:Animals; D001565:Benzoates; D019817:Benzoic Acid; D002417:Cattle; D004247:DNA; D005520:Food Preservatives; D013056:Spectrophotometry, Ultraviolet; D013447:Sulfites; D013950:Thymus Gland
chemical_list: D001565:Benzoates; D005520:Food Preservatives; D013447:Sulfites; D019817:Benzoic Acid; D004247:DNA; D000241:Adenosine; C025026:sodium sulfite