Diurnal variation of rat liver enzymes catalyzing bile acid conjugation and sulfation.
This study investigated the diurnal variation in the activity of the hepatic enzymes catalyzing conjugation and sulfation of bile acids. A circadian rhythm was noted in cholic acid : CoA ligase and glycolithocholate sulfotransferase activity. There was no diurnal variation in lithocholate sulfotransferase activity raising the possibility of multiple bile acid sulfotransferases in liver.
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism*; D002793:Cholic Acids / Q000378:metabolism; D002855:Chromatography, Thin Layer; D002940:Circadian Rhythm; D008025:Ligases / Q000378:metabolism; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D014166:Transferases / Q000378:metabolism
D001647:Bile Acids and Salts; D002793:Cholic Acids; D014166:Transferases; D008025:Ligases