Primary gastric choriocarcinoma. An immunohistological study.
Two cases of extragenital choriocarcinoma arising in association with gastric adenocarcinoma are described. Using immunohistochemical methods, cells containing human chorionic gonadotropin, beta-subunit (hCG-beta) were localized exclusively to the choriocarcinomatous portion of the tumor. One patient whose tumor appeared to confined to the stomach at the time of surgery, had elevated serum hCG-beta postoperatively. Metastases became evident subsequently.
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D002822:Choriocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D011247:Pregnancy; D013274:Stomach Neoplasms / Q000473:pathology*