[Effect of genetic and environmental factors on the variability of the lipid and lipoprotein concentration in the blood plasma].
Family and twin data (45 parent -- children and 35 MZ and 55 DZ pairs) with average age of 37 years were analysed. The type of zygocity was determined by phenotyping erythrocyte enzymes and serum antigens and by calculating discriminative functions with the use of antropometric, antroposcopic, and dermatoglyphic measurements. The distribution component of phenotypic dispersion was made from correlation between relatives according to the Trubnikov - Gindilis - Finogenova scheme. The following distribution was obtained: with CH the genetic additive Ga = 82%, the genetic dominant Gd = 0%, and the environmental commom Ec = 0%, environmental within Ew = 18%; with TG, Ga = 46%, Gd = 2%, Ec = 21%, and Ew = 31%; with CH-HDL, Ga = 50%, Gd = 0%, Ec = 16%, and Ew = 34%. The importance of genetic and environmental components in the determination of CH, TG, CH-HDL, CH-LDL in plasma is discussed.
D000328:Adult; D000375:Aging; D004782:Environmental Health; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008055:Lipids / Q000097:blood* / Q000235:genetics; D008074:Lipoproteins / Q000097:blood* / Q000235:genetics; D008875:Middle Aged; D008957:Models, Genetic; D010641:Phenotype; D011247:Pregnancy; D012044:Regression Analysis; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic
D008055:Lipids; D008074:Lipoproteins
Vliianie geneticheskikh i sredovykh faktorov na izmenchivost' kontsentratsii lipidov i lipoproteidov v plazme krovi.