title: The exclusion of patients from a clinical trial.
abstract: In designing a clinical trial, the investigator must often decide whether or not to exclude certain patients from randomization. Using Bayesian analysis this paper proposes a criterion for making this decision, based on an extension of Colton's model for the choice between two medical treatments.
mesh_terms: D001499:Bayes Theorem; D002986:Clinical Trials as Topic; D006801:Humans; D008954:Models, Biological; D010361:Patients; D011336:Probability; D011897:Random Allocation