title: Population genetical aspects of primary congenital glaucoma. I. Incidence, prevalence, gene frequency, and age of onset.
abstract: This paper presents some characteristics of the population genetics of primary congenital glaucoma in Slovakia. The overall incidence in Slovakia is 1:10,500, while being 1:1,250 in the Gypsy subpopulation of Slovakia and 1:22,000 in the non-Gypsy population. For a special type of congenital primary glaucoma, transmitted by autosomal recessive inheritance in Gypsies the gene frequency may be estimated to reach 2.8%. Early onset of the disease enabling diagnosis soon after birth in 82% of patients may be considered another characteristic of this type of primary congenital glaucoma.
mesh_terms: D000367:Age Factors; D003604:Czechoslovakia; D005006:Ethnicity; D005787:Gene Frequency; D005828:Genetics, Population; D005901:Glaucoma / Q000151:congenital* / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D006178:Romani People