title: The theory of sets as a tool in systematic drug design.
abstract: A strategy of practical drug design is developed on the basis of the theory of sets. This strategy accounts for the fact that new drugs are required to optimally approach a certain activity profile rather than showing maximal intrinsic activity. In addition, modern structure selection techniques as well as qualitative and quantitative structure-activity relationships are incorporated in the strategy so as to optimally contribute to an economical use of experimental capacity.
mesh_terms: D002626:Chemistry, Pharmaceutical; D007093:Imidazoles; D008433:Mathematics; D008954:Models, Biological; D013329:Structure-Activity Relationship
chemical_list: D007093:Imidazoles; C029758:sulmazole