[Effect of phenamine and haloperidol on stereotyped behavior in response to electric stimulation of the substantia nigra in cats].
On being given in low doses (0.25 mg/kg) amphetamine potentiates stereotyped behavior induced in cats by stimulation of substantia nigra. As the dose is raised the effect increases eventuating in the formation of the typical amphetamine-induced stereotypy. Little doses of haloperidol (0.03-0.06 mg/kg) reduce the behavioral and electroencephalographic signs of nigral stereotypy. Amphetamine potentiates, while haloperidol reduces the impairment of the restrained function of the caudate nucleus which occurs in the presence of nigral stereotypy.
D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D001931:Brain Mapping; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects; D004558:Electric Stimulation; D004569:Electroencephalography; D005260:Female; D006220:Haloperidol / Q000494:pharmacology*; D006801:Humans; D008297:Male; D013239:Stereotyped Behavior / Q000187:drug effects* / Q000502:physiology; D013378:Substantia Nigra / Q000502:physiology
D000661:Amphetamine; D006220:Haloperidol
Vliianie fenamina i galoperidola na stereotipnoe povedenie, voznikaiushchee u koshek pri élektricheskom razdrazhenii chernoĭ substantsii.