[A new and quick method for determination of allopurinol and oxipurinol in serum (author's transl)].
A method is described for allopurinol and oxipurinol assay in human serum for concentrations reached after usual therapy. The HPLC-method is based on a quick preparation of the serum samples including protein precipitation, evaporation to dryness, dissolving of the residue in citric acid and injecting the final solution on to the HPLC column. Detection limits for allopurinol are 0.05 microgram/ml serum and for oxipurinol 0.2 microgram/ml serum.
D000493:Allopurinol / Q000097:blood*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D066298:In Vitro Techniques; D010117:Oxypurinol / Q000097:blood*; D011743:Pyrimidines / Q000097:blood*
D011743:Pyrimidines; D000493:Allopurinol; D010117:Oxypurinol
Eine neue, rasche Bestimmungsmethode für Allopurinol und Oxipurinol im Serum.