Amphetamine-induced rotation in normal cats.
Amphetamine elicited dose-related rotation (circling behavior) in 9 naive cats; all cats also rotated, at lower rates, during non-drug sessions. The direction of rotation was consistent for each cat, with 6 cats rotating to the right and 3 to the left. The results extend the generality of previous findings involving rodents and suggest that an endogenous asymmetry in striatal dopamine activity may be a common characteristic of many animal species.
D000818:Animals; D002415:Cats; D003913:Dextroamphetamine / Q000494:pharmacology*; D004292:Dominance, Cerebral / Q000187:drug effects; D004298:Dopamine / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D013239:Stereotyped Behavior / Q000187:drug effects*
D003913:Dextroamphetamine; D004298:Dopamine