[Effect of emotional stress on the frequency of chromosome aberrations in the bone marrow cells of mice].
The chromosome aberration rate was studied in bone marrow cells of C57BL/6, CBA and BALB/c mice before and after emotional stress. After "the opened field" experiment the chromosome aberration rate in C57BL/6 and CBA mice increased while that in BALB/c mice remained unchanaed. The mutagenic effect was prevented by phenazepam.
D000818:Animals; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000627:therapeutic use; D001853:Bone Marrow / Q000648:ultrastructure*; D002869:Chromosome Aberrations / Q000187:drug effects; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013315:Stress, Psychological / Q000188:drug therapy / Q000235:genetics*
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D001569:Benzodiazepines; C017928:phenazepam
Vliianie émotsional'nogo stressa na chastotu khromosomnykh aberratsiĭ v kletkakh kostnogo mozga mysheĭ.