title: [Prevention of aspiration pneumonia with cimetidine].
abstract: Aspiration of gastric acid is one of the most feared narcosis complications. The currently practiced methods of prophylaxis did not reduce the frequency of aspiration pneumonitis. In a prospective randomised study orally and intramuscularly given Cimetidine significantly reduced the toxicity of stomach contents. The intramuscular route proved to be superior. Preoperative prophylactic use of Cimetidine can be a useful method to reduce the frequency of Mendelson's syndrome without disadvantages.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002927:Cimetidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011015:Pneumonia, Aspiration / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control
chemical_list: D006146:Guanidines; D002927:Cimetidine
vernacular_title: Prophylaxe der Aspirationspneumonie mit Cimetidin.