Congenital hypoplastic anaemia developed in acute megakarioblastic leukaemia. A case report.
A 14-month-old child with congenital hypoplastic anemia, in temporary remission after steroid therapy, developed an acute megakarioblastic leukemia. After complete remission due to immunosuppressive treatment, the leukemia rapidly relapsed, and the child died at 23 months of age. The rapid development of leukemia puts some doubt on the initial diagnosis.
D000208:Acute Disease; D000741:Anemia, Aplastic / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D001803:Blood Transfusion; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013920:Thrombocythemia, Essential / Q000175:diagnosis*
D011241:Prednisone