title: Twin-family studies of perceptual speed ability. II. Parameter estimation.
abstract: Offspring of monozygotic (MZ) twins form half-ships that permit a direct test of maternal effects and differentiate several sources of between-family environmental variance. Combined with conventional twin data, these genetic half-sibships provide a unique data set for estimating sources of variation in quantitative traits. To illustrate, genetic and environmental parameters were estimated for Identical Pictures Test data obtained from children of MZ twin parents and an (approximate) age-matched cohort of like-sex twins. Analyses of variance of the data, standardized for age and sex, yield 12 mean squares to which gene-environment models were fit. Maximum-likelihood estimation revealed a complete absence of maternal influences and shared environmental effects; a simple two-parameter model, assuming random mating and attributing variation in test scores to additive genes and within-family environment, adequately accounts for the familial data.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004193:Discrimination Learning; D005260:Female; D005556:Form Perception; D014644:Genetic Variation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010364:Pattern Recognition, Visual; D011247:Pregnancy; D011930:Reaction Time; D012931:Social Environment; D014427:Twins; D014430:Twins, Monozygotic