title: Conditional fear, anxiety, and morphine-seeking behavior.
abstract: Two Cebus albifrons monkeys were given discriminative operant conditioning with visual stimuli, with Sidman avoidance and punishment as the components. The instrumental response was an unelicited increase in skin conductance. Both animals had surgically implanted catheters for automatic injection of morphine into the heart. After autonomic conditioning, the animals were given the opportunity to self-administer the morphine by touching the primate press panel that displayed the visual stimuli. One contingency-free segment per session was used for morphine injection, while the contingencies remained in force during the other segments. One of the monkeys made significantly more skin conductance responses during avoidance than during punishment, and this monkey received ten times as many shocks in punishment. This monkey also made more responses overall and had a much higher heart rate than the other animal. The other monkey did not differentiate significantly autonomically and received equal numbers of shocks in avoidance and punishment. The monkey that showed autonomic differentiation made significantly (and increasingly) more panel-presses during punishment than during avoidance. The other animal showed hardly any tendency at all to panel-press.
mesh_terms: D000818:Animals; D001007:Anxiety; D001362:Avoidance Learning; D001522:Behavior, Animal; D002428:Cebus; D003216:Conditioning, Operant; D004558:Electric Stimulation; D005239:Fear; D006339:Heart Rate; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage; D009021:Morphine Dependence; D011678:Punishment; D012054:Reinforcement, Psychology; D012879:Skin Physiological Phenomena
chemical_list: D009020:Morphine