[Correlative role of genetic and environmental factors in the cholesterol variability of high-density lipoproteins and their subclasses].
The correlative contribution of environmental and genetic factors in determining the levels of cholesterol (CS) of high density lipoproteins (HDLP) and their subfractions (HDLP2 and HDLP3) was studied on a twin model. The predominant role of the genetic component in the interindividual variability of CS HDLP3 both in females and in males and a relatively greater contribution of the environmental component in CS HDLP2 variability were revealed. This explains the greater lability of CS HDLP2 concentrations under different environmental effects.
D000328:Adult; D002784:Cholesterol / Q000235:genetics*; D004777:Environment; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008075:Lipoproteins, HDL / Q000145:classification / Q000235:genetics*; D008297:Male; D010641:Phenotype; D011247:Pregnancy; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic
D008075:Lipoproteins, HDL; D002784:Cholesterol
Issledovanie sootnositel'nĭ roli geneticheskikh i sredovykh faktorov v izmenchivosti kholesterina lipoproteidov vysokoĭ plotnosti i ikh podklassov.