Human melanoma antigen AH is an autoantigenic ganglioside related to GD2.
AH antigen, initially defined by an antibody present in a melanoma patient, is a cell surface antigen found on approximately 65% of melanoma cell lines. Absorption analysis indicates that AH is a differentiation antigen marking normal and malignant cells of neuroectodermal origin. The AH determinant has been found to be related to GD2 ganglioside.
D000941:Antigens / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis* / Q000276:immunology; D001324:Autoantigens / Q000032:analysis*; D001667:Binding, Competitive; D002460:Cell Line; D005678:G(M2) Ganglioside / Q000276:immunology* / Q000494:pharmacology; D005732:Gangliosides / Q000276:immunology*; D006801:Humans; D008545:Melanoma / Q000276:immunology*; D010641:Phenotype
D000941:Antigens; D000951:Antigens, Neoplasm; D001324:Autoantigens; D005732:Gangliosides; D005678:G(M2) Ganglioside