Bilateral encephaloclastic lesions in a 26 week gestation fetus: effect on neuroblast migration.
A 26 week gestation fetus with bilaterally symmetrical encephaloclastic lesions in the cerebral hemispheres is described. Information about gestation allows dating of the cerebral insult to the 3-4th fetal month. The history and morphology in this case suggest that insults occurring at or before the 3-4th fetal month interfere with normal neuroblast migration, producing a cerebral scar containing a band of neuroblasts arranged without order or lamination.
D000328:Adult; D001921:Brain / Q000473:pathology*; D002465:Cell Movement; D002540:Cerebral Cortex / Q000196:embryology / Q000473:pathology; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology*; D008831:Microcephaly / Q000473:pathology*; D009474:Neurons / Q000473:pathology