[Correlation between the stress-protective and vegetotropic action of mebikar].
Mebicar, a tranquilizer of the group of tetra-N-alkyl bicyclic bis-ureas, under acute emotional stress in cats (confrontation with a dog), simultaneously with tranquilizing effect on behavior also improves central baroreflex control and reduces hypertensive reaction of the arterial pressure. In rats, it normalizes disorders of individual and intraspecies behavior induced by the stress of a long-term social isolation. It decreases the degree of ulcer injury of the stomach during the immobilization stress.
D000818:Animals; D000897:Anti-Ulcer Agents; D000959:Antihypertensive Agents; D001736:Biureas / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D001952:Bridged-Ring Compounds / Q000627:therapeutic use*; D002415:Cats; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000517:prevention & control; D011311:Pressoreceptors / Q000187:drug effects; D051381:Rats; D012018:Reflex / Q000187:drug effects; D013276:Stomach Ulcer / Q000517:prevention & control; D013315:Stress, Psychological / Q000188:drug therapy*
D000897:Anti-Ulcer Agents; D000959:Antihypertensive Agents; D001736:Biureas; D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; C015979:mebikar
Korreliatsiia stress- protektivnogo i vegetotropnogo deĭstviia mebikara.