title: Preliminary studies on the use of an oral progestogen to induce oestrus and ovulation in seasonally anoestrous Thoroughbred mares.
abstract: Daily oral administration of 30 mg allyl trenbolone (Regumate) for 10 to 15 days to 61 barren, maiden and lactating Thoroughbred mares which were exhibiting either deep anoestrus, shallow anoestrus, prolonged spring oestrus or lactation anoestrus, resulted in 54 mares (88 per cent) showing oestrous behaviour within 8 days, and 51 mares (84 per cent) ovulating within 18 days, after the last dose of compound. Response rate was lowest in mares in deep anoestrus. Of the 38 Regumate-treated mares which were covered during the induced oestrus, 21 (55 per cent) conceived. The practical value of this form of progesterone withdrawal therapy as a method for hastening the onset of the breeding season in Thoroughbred mares is discussed.
mesh_terms: D000780:Anestrus; D000818:Animals; D004963:Estrenes / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects*; D005260:Female; D006736:Horses; D010060:Ovulation / Q000187:drug effects*; D011247:Pregnancy; D012621:Seasons; D014204:Trenbolone Acetate / Q000031:analogs & derivatives / Q000494:pharmacology*
chemical_list: D004963:Estrenes; C023445:altrenogest; D014204:Trenbolone Acetate