The collagen of permanently damaged nerves in human leprosy.
The collagen of nerve biopsies from ten leprosy patients was studied by the Picrosirius-polarization method and electron microscopy. It was observed that leprosy promotes a marked increase in nerve collagen content. Despite the changes induced by this disease, the localization of collagen types I and III in the endo-, peri-, and epineurium remains the same as in normal nerves.
D001706:Biopsy; D003094:Collagen / Q000378:metabolism*; D006801:Humans; D007918:Leprosy / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D009443:Neuritis / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D009474:Neurons / Q000473:pathology / Q000648:ultrastructure*
D003094:Collagen