title: [Drug side effects as the probable cause of death. Results of the Berne Comprehensive Hospital Drug Monitoring Program].
abstract: During the years 1974-1980, 19 of 17,285 inpatients of the divisions of internal medicine of two teaching hospitals showed a probable or definite adverse drug reaction (ADR) which was considered to be a major cause of death. In 7 patients the decisive ADR occurred during the hospital stay. The overall mortality from ADR is 0.040%. For each therapeutic group of drugs the following rate of drug-related death was calculated: for anticoagulants 0.047% (3/6378 inpatients), for cardiac glycosides 0.016% (1/6368), for analgesic/antirheumatic drugs 0.014% (1/7112) and for cytostatic drugs 0.38% (2/531). In 12 patients the ADR was already present on hospital admission.
mesh_terms: D000368:Aged; D003643:Death; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D011358:Product Surveillance, Postmarketing; D013557:Switzerland
vernacular_title: Medikamentnebenwirkungen als wahrscheinliche Todesursache. Ergebnisse aus dem Komprehensiven Spital Drug Monitoring Bern (CHDMB).