Chronic granulomatous disease and McLeod syndrome in a black child.
A 3-year-old black male child with X-linked chronic granulomatous disease and red cells of the rare McLeod phenotype is presented. The red cells showed acanthocytosis and did not react with anti-KL. Similarly the leukocytes were nonreactive with anti-Kx. The Xk and Xg linkage could not be investigated since all members of his family were Xg (a+).
D000050:Acanthocytes / Q000473:pathology; D001741:Black or African American; D001789:Blood Group Antigens / Q000235:genetics*; D002675:Child, Preschool; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000097:blood* / Q000235:genetics / Q000473:pathology; D006801:Humans; D007626:Kell Blood-Group System / Q000235:genetics*; D008297:Male; D013577:Syndrome; D014960:X Chromosome
D001789:Blood Group Antigens; D007626:Kell Blood-Group System