Effects of an antiprostaglandin drug on human fallopian tubes in vivo.
The Authors studied 17 patients with patent tubes, normal ovulation and Rubin's test results. In the following cycle, this test was repeated divided into two phases. The first followed the normal procedure; the second started 10' after the e.v. administration of 50 mg of an antiprostaglandin drug (Ketoprophen). The results highlighted the capability of this drug to alter the activity of human tubes. A general increase was observed in the amplitude and frequency of tubal contractions. The Authors finally analyse the possible clinical use of this drug in the treatment of the tubal pathology.
D000328:Adult; D005186:Fallopian Tube Patency Tests; D005187:Fallopian Tubes / Q000187:drug effects*; D005260:Female; D006801:Humans; D007660:Ketoprofen / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010060:Ovulation; D010666:Phenylpropionates / Q000494:pharmacology*; D011448:Prostaglandin Antagonists / Q000494:pharmacology*
D010666:Phenylpropionates; D011448:Prostaglandin Antagonists; D007660:Ketoprofen