Naevus comedonicus in homozygous twins.
This is the first case report of bilateral naevus comedonicus seen in a pair of twins in Singapore. 3 other family members were similarly affected. Though both sexes were affected, there were more males affected as compared to females. Recent reports support a familial inheritance. Our pedigree showed an autosomal dominant inheritance. The extensive involvement seen in the twins suggest that they may be homozygous for this condition.
D000293:Adolescent; D004200:Diseases in Twins; D005260:Female; D006720:Homozygote; D006801:Humans; D008297:Male; D009506:Nevus / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D011247:Pregnancy; D012867:Skin / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000235:genetics* / Q000473:pathology; D014427:Twins; D014430:Twins, Monozygotic