title: Effects of weight reduction on arterial pressure.
abstract: Obesity and hypertension are closely correlated. Weight loss obtained with hypocaloric diet and without reduced sodium intake affected a considerable fall in systolic and diastolic pressures in overweight hypertensive patients. This pressure-weight reduction was maintained for at least 12-18 months. The mechanism(s) for the pressure reduction may be explained by a decreased sympathetic activity associated with a reduced participation of the renin-angiotensin-aldosterone system, natriuresis, contracted plasma volume, and a reversal of the high cardiac output state.
mesh_terms: D001794:Blood Pressure; D001835:Body Weight; D002302:Cardiac Output; D004038:Diet, Reducing; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000178:diet therapy; D009318:Natriuresis; D009765:Obesity / Q000178:diet therapy; D010953:Plasma Volume; D012084:Renin-Angiotensin System; D013564:Sympathetic Nervous System / Q000502:physiology
chemical_list: D004040:Dietary Carbohydrates