[Stress-protective effect of diazepam and its combinations with adrenergic and dopaminergic substances in rats according to the operant activity test].
Experiments on rats trained active avoidance according to Sidman have shown that optimal correction of the operative activity disorders induced by immobilization of the animals and diazepam administration is provided by administering midantan, apomorphine, dopamine and nuredal rather than by amphetamine, sydnocarb and clonidin. The results obtained favour the administering of dopaminomimetics as correctors of psychodepressant effects of diazepam.
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D003216:Conditioning, Operant / Q000187:drug effects*; D003975:Diazepam / Q000494:pharmacology*; D004298:Dopamine / Q000031:analogs & derivatives*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D006801:Humans; D008297:Male; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000517:prevention & control*; D013566:Sympathomimetics / Q000494:pharmacology*
D013566:Sympathomimetics; D003975:Diazepam; D004298:Dopamine
Stress-protektivnyĭ éffekt diazepama i ego kombinatsiĭ s adrenergicheskimi i dofaminergicheskimi veshchestvami u krys po testu operantnoĭ deiatel'nosti.