Hemorheologic conditions in patients with cerebrovascular disease altered by treatment with pentoxifylline.
In 55 patients with acute or subacute CVD a beneficial but dose dependent effect of PO on human blood rheologic properties has been demonstrated, indicated by a lowering of blood viscosity, a decrease of fibrinogen concentration and inhibition of PA.
D001809:Blood Viscosity / Q000187:drug effects*; D002561:Cerebrovascular Disorders / Q000097:blood*; D004341:Drug Evaluation; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006400:Hematocrit; D006801:Humans; D008297:Male; D010431:Pentoxifylline / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D012212:Rheology; D013805:Theobromine / Q000031:analogs & derivatives*
D005340:Fibrinogen; D013805:Theobromine; D010431:Pentoxifylline