title: [Evolutionary changes in the genetic code, predictable on basis of the hypothesis of physical predetermination of the structure of codon bases].
abstract: According to the earlier proposed hypothesis on the structural correspondence between amino acids and doublets from the first codon bases (Sukhodolets 1980), the UGA triplet corresponds to tryptophan and the AGX triplets - to the termination codons. It is notably this sense of the UGA and AGA, AGG, respectively, that was reported for mitochondrial codes. Thereby, a proposal is indirectly confirmed that meanings of the UGA (nonsense) and AGA, AGG (arginine) in the normal cytoplasmic code is the result of evolutionary changes.
mesh_terms: D000596:Amino Acids / Q000235:genetics; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D003062:Codon / Q000235:genetics*; D005815:Genetic Code; D008928:Mitochondria / Q000648:ultrastructure; D009491:Neurospora / Q000235:genetics; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics*; D015003:Yeasts / Q000235:genetics
chemical_list: D000596:Amino Acids; D003062:Codon; D012333:RNA, Messenger
vernacular_title: Evoliutsionnye preobrazovaniia geneticheskogo koda, predskazyvaemye iskhodia iz gipotezy o fizicheskom predopredelenii naborov osnovaniĭ v sostava kodonov.