title: [Effect of laxative measures on the serum concentration of digoxin in the human].
abstract: Plasma digoxin levels were measured in patients on laxatives during the initial phase and during the steady state of digoxin intake. Plasma digoxin levels were significantly lower during intake of laxatives. Reduced intestinal resorption may be due to accelerated passage through the intestinal tract and to alteration of distribution volumes.
mesh_terms: D000113:Acetyldigoxins / Q000097:blood; D000328:Adult; D000368:Aged; D001726:Bisacodyl / Q000627:therapeutic use*; D002400:Cathartics / Q000627:therapeutic use*; D003408:Cresols / Q000627:therapeutic use*; D004077:Digoxin / Q000097:blood*; D006801:Humans; D007700:Kinetics; D008875:Middle Aged
chemical_list: D000113:Acetyldigoxins; D002400:Cathartics; D003408:Cresols; D001726:Bisacodyl; D004077:Digoxin
vernacular_title: Einfluss von abführmassnahmen auf die Serumkonzentration von Digoxin beim Menschen.