title: [Neurological complications in drug dependence with special reference to the development of epileptic syndromes].
abstract: 33 drug abusers were examined and all of them were addicts to several drugs and always to heroin. Neurological complications occurred rather frequently. One patient had subarachnoid hemorrhage and angiography showed no arteriovenous malformations nor other pathology. Polyneuropathy has been found in one case. 7 patients (21,2%) developed psychotic episodes. Epileptic attacks were found in 5 cases (15,1%). Latency between the onset of drug-abusing and occurrence of the attacks was found to be at least 1 year in two cases and 3 years in the other three. 4 cases suffered from partial complex seizures with secondary generalization and one patient had generalized tonic-clonic attacks. Fits occurred rarely in all cases; one patient had two episodes of partial status. Further research is required because there are few clinical reports in comparison with the experimental ones.
mesh_terms: D000293:Adolescent; D000328:Adult; D004827:Epilepsy / Q000139:chemically induced*; D005260:Female; D006556:Heroin Dependence / Q000150:complications; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000139:chemically induced*; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D019966:Substance-Related Disorders / Q000150:complications*; D013577:Syndrome; D013997:Time Factors
vernacular_title: Complicanze neurologiche nelle tossicodipendenze, con particolare riguardo all'insorgenza di sindromi epilettiche.