Warfarin embryopathy in siblings.
Two siblings were noted to have the physical stigmata of the fetal warfarin syndrome. Their mother had received warfarin sodium for thrombophlebitis during both pregnancies but not during that of an unaffected sibling. Teratogens may produce syndromes that mimic genetic disease in both phenotype and familial aggregation.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D002386:Cataract / Q000139:chemically induced; D002675:Child, Preschool; D002806:Chondrodysplasia Punctata / Q000139:chemically induced; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D009666:Nose / Q000196:embryology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy; D013723:Teratogens; D013924:Thrombophlebitis / Q000188:drug therapy; D014859:Warfarin / Q000009:adverse effects*
D013723:Teratogens; D014859:Warfarin