Experience with the induction of second-trimester abortion by extra-amniotic physiological saline infusion. Report of 127 cases.
In 127 women with normal second-trimester pregnancy we induced abortion by extraamniotic (EA) physiological saline infusion. All women aborted within 72 h, most of them during the first 24 h. Besides a transient fever in one case, no complications or side effects were recorded. This method is safe and cheap, and entirely without contraindications. Therefore, it may be used in cases when other methods would have been dangerous or failed. As for the mechanism of action of this method, it is probably by the secretion of intrinsic prostaglandins, produced by the decidual cells. But this hypothesis remains to be proved.
D000028:Abortion, Induced / Q000379:methods*; D000293:Adolescent; D000328:Adult; D000650:Amnion; D005260:Female; D006801:Humans; D010121:Oxytocin / Q000627:therapeutic use; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012965:Sodium Chloride / Q000008:administration & dosage*; D013997:Time Factors
D012965:Sodium Chloride; D010121:Oxytocin