Effect of cold exposure on peroxidase and iodinase activities of rat submandibulary gland.
Exposure of rats to 6 +/- 2 degrees C for 3 h caused an increase in peroxidase activity (55%) and tyrosine iodinase activity (40%) of the submandibulary glands. Thiocyanate, hydrogen peroxide and formation of triiodide from iodide were also elevated under the same conditions. Administration of alpha-receptor blockers and indomethacin prevented the rise of peroxidase activity during cold stress whereas beta-receptor blockers were less effective.
D000818:Animals; D003080:Cold Temperature; D066298:In Vitro Techniques; D007453:Iodide Peroxidase / Q000378:metabolism*; D008297:Male; D010544:Peroxidases / Q000378:metabolism*; D011448:Prostaglandin Antagonists / Q000494:pharmacology; D051381:Rats; D013363:Submandibular Gland / Q000201:enzymology*
D011448:Prostaglandin Antagonists; D010544:Peroxidases; D007453:Iodide Peroxidase