Study of phagocytic function with a quantitative nitroblue-Tetrazolium (NBT) reduction test in diabetes mellitus.
In 40 patients suffering from diabetes mellitus and in 18 healthy volunteers the phagocytic function was investigated using a quantitative NBT test. The NBT reduction was significantly lower in diabetes than in healthy donors irrespective of affliction with other dermatoses. A significant correlation was found between the severity and hence the insulin dependency of diabetics and the NBT-reductive capacity.
D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus; D005260:Female; D006098:Granulocytes / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009580:Nitroblue Tetrazolium; D010084:Oxidation-Reduction; D010587:Phagocytosis; D013778:Tetrazolium Salts; D015054:Zymosan / Q000494:pharmacology
D013778:Tetrazolium Salts; D009580:Nitroblue Tetrazolium; D015054:Zymosan