Synthesis and pharmacological activity of modified leu-enkephalin derivatives. III.
The synthesis and pharmacological activity of Leu-enkephalins carrying a free or substituted carboxymethyl group at glycine-2-nitrogen are described.
D000818:Animals; D004723:Endorphins / Q000138:chemical synthesis*; D004743:Enkephalin, Leucine; D004745:Enkephalins / Q000138:chemical synthesis*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects
D004723:Endorphins; D004745:Enkephalins; D004743:Enkephalin, Leucine