[Acrobullous photodermatitis caused by PUVA: measurement of dermo-epidermal adhesion].
In 65 patients suffering from psoriasis treated with photochemotherapy and 32 healthy controls the dermo-epidermal junction was measured by experimental blistering. A significantly shortened blistering time was shown in PUVA-patients. The reasons in discussion are the increase of activated melanocytes (clear cells) in the basal membrane region and changes in the connective tissue by long term PUVA-therapy.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001768:Blister / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D011701:PUVA Therapy / Q000009:adverse effects*; D010778:Photochemotherapy / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology
Akrobullöse Photodermatose bei PUVA: Messung der dermoepidermalen Kohäsion.