Receptors to Dolichos biflorus agglutinin. A new cell surface marker common to teratocarcinoma cells and preimplantation mouse embryos.
Dolichos biflorus agglutinin (DBA), a lectin specific to N-acetylgalactosamine residue, identifies cell surface markers on teratocarcinoma cells. These receptors are found in very limited types of adult tissues. In the present investigation, mouse embryos collected on day 1 (2-cell) to 3 (early blastocyst) were shown to be stained with FITC-conjugated DBA. Embryos homozygous for tw32 were also positively stained. These results suggest that receptors for DBA on preimplantation embryos include components distinct from Forssman, F9, and SSEA-1 antigens.
D000818:Animals; D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis*; D005260:Female; D037102:Lectins; D051379:Mice / Q000196:embryology*; D009374:Neoplasms, Experimental / Q000276:immunology; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000032:analysis; D013724:Teratoma / Q000276:immunology*; D015053:Zygote / Q000276:immunology
D000951:Antigens, Neoplasm; D000954:Antigens, Surface; C027654:Dolichos biflorus lectin receptor; D037102:Lectins; D037121:Plant Lectins; D011975:Receptors, Mitogen; C036554:dolichos biflorus agglutinin