Thiabendazole-resistant strains of Haemonchus and Ostertagia in California lambs.
Ten parasite-free experimental lambs were inoculated intraruminally with a mixed-larvae inoculum which contained approximately 5,000 Haemonchus contortus infective larvae. Five lambs were treated with thiabendazole (66 mg/kg of body weight) and 5 were untreated controls. All lambs were killed 35 days after inoculations were done, and parasites present were recovered. Reduction in numbers of recovered Haemonchus contortus (25.7%) and Ostertagia spp (26.8%) were not significant (P greater than 0.05).
D000818:Animals; D004351:Drug Resistance; D005069:Evaluation Studies as Topic; D005243:Feces / Q000469:parasitology; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary*; D006189:Haemonchus / Q000302:isolation & purification; D010029:Ostertagiasis / Q000188:drug therapy / Q000662:veterinary*; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D013827:Thiabendazole / Q000627:therapeutic use*; D014251:Trichostrongyloidea / Q000302:isolation & purification; D014252:Trichostrongyloidiasis / Q000662:veterinary*
D013827:Thiabendazole