Postoperative pseudomembranous colitis associated with ampicillin therapy.
A case of pseudomembranous colitis in a 66-year-old subject is presented. The disease appeared on the fourth postoperative day following prostatectomy. On the first postoperative day ampicillin was administered intramuscularly (4 g/day). On the seventh postoperative day, toxic megacolon complicated the disease and a diverting ileostomy with decompression colostomies was performed. The patient died two days later due to severe respiratory failure following extensive bronchopulmonary infection.
D000368:Aged; D000667:Ampicillin / Q000009:adverse effects*; D001437:Bacteriuria / Q000188:drug therapy; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy; D011468:Prostatectomy / Q000009:adverse effects
D000667:Ampicillin