title: Clinical trials, reviews, and the Journal of Negative Results.
abstract: 1 Eighteen our of twenty non-significant placebo controlled trials are shown to have trends favouring imipramine and are consistent with a further ten significant at 0.05. 2 The problems of falsely positive and falsely negative results are discussed. A plea is made to medical journal editors to publish 'negative' or null difference trials by title only; rather than not at all.
mesh_terms: D002986:Clinical Trials as Topic; D004358:Drug Therapy; D006801:Humans; D010919:Placebos; D012107:Research Design; D013223:Statistics as Topic
chemical_list: D010919:Placebos