title: [Eczematoid dermo-epidermitis].
abstract: A methodic study of 50 cases, had to the discussion of a real clinical well established entity. The lesions start from an initial site, located on the inferior limbs in 2/3rd of the cases; then within a variable period of time extend larger and larger by proliferating in numerous patches. These lesions present as polymorphic, erythemato-squamous or oozing. They often evolve towards recurrence. The disease is more frequently encountered among 50-year-old men. Several factors contribute to the onset of the lesions: chronic alcoholism--lack of sanitary conditions--microbial background--stasis--overweight. A disturbed system of cutaneous protection and a lack of immune defences versus an antigen, probably a bacteria, are at the origin of the pathogenesis of these disorders. Considering the treatment, we wish to underline the benefit of local coal tar applications.
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000437:Alcoholism / Q000150:complications; D000989:Antistreptolysin / Q000032:analysis; D003033:Coal Tar / Q000627:therapeutic use; D004485:Eczema / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D012737:Sex Factors; D012959:Socioeconomic Factors
chemical_list: D003033:Coal Tar; D000989:Antistreptolysin
vernacular_title: Les dermo-épidermites eczématoïdes.