Mollaret meningitis: report of a case with recovery after colchicine.
A 13-year-old boy developed closely spaced episodes of recurrent febrile meningitis that persisted for 22 months despite antibiotic therapy. During exacerbations the cerebrospinal fluid contained up to 2,500 leukocytes per cubic millimeter, including up to 20% activated monocytoid cells, with high IgM and IgG levels. No cause for the disorder was found, but steroids improved the condition and colchicine therapy apparently cured it.
D000293:Adolescent; D003078:Colchicine / Q000627:therapeutic use*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007964:Leukocytosis / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D008297:Male; D008581:Meningitis / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D008775:Methylprednisolone / Q000627:therapeutic use*; D013577:Syndrome
D007136:Immunoglobulins; D003078:Colchicine; D008775:Methylprednisolone