Influence of hormones on testicular lipids of adult rats.
Testosterone, oestradiol-17 beta, progesterone and prolactin were administered for 1 and 7 days to adult rats to study the short- and long-term effects of these hormones on testicular lipids. Testosterone administration induced a marked increase in testicular phospholipids and a significant fall in glycerides. Oestrogen, on the other hand, provoked a significant increase in total lipids and glycerides with no marked changes in testicular phospholipids. Progesterone elicited significant changes in cholesterol fractions; a marked increase in esterified cholesterol with a concurrent fall in free cholesterol was observed. Prolactin treatment resulted in a significant fall in total lipids and phospholipids with no marked change in tissue weight. It also induced a marked fall in total and free cholesterol with a significant increase in esterified cholesterol.
D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D002788:Cholesterol Esters / Q000378:metabolism; D004958:Estradiol / Q000494:pharmacology*; D005989:Glycerides / Q000378:metabolism; D050356:Lipid Metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D011374:Progesterone / Q000494:pharmacology*; D011388:Prolactin / Q000494:pharmacology*; D051381:Rats; D013737:Testis / Q000187:drug effects / Q000378:metabolism*; D013739:Testosterone / Q000494:pharmacology*
D002788:Cholesterol Esters; D005989:Glycerides; D010743:Phospholipids; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D002784:Cholesterol