[Concentration of neuraminic acid in the serum of tumor patients (author's transl)].
The neuraminic acid level in the serum of 588 patients was determined. The patients suffered from bronchial carcinomas other malignant diseases (mastocarcinoma, carcinoma of the cervix and the body of the uterus, Hodgkin's lymphoma, non-Hodgkin's lymphoma), and benign pulmonary diseases (tuberculosis of the lungs and chronic obstructive pulmonary diseases). The average level of 162 patients with bronchial carcinomas is 3,449 mumol/ml of serum; thus it is significantly higher than the average level of 98 sound control persons (2,336 mumol/ml) and 88 patients with benign pulmonary diseases (2,733) mumol/ml). The other patients with malignant diseases also presented an increased concentration of neuraminic acid in the serum, however, this increase was not as significant as for the patients with bronchial carcinomas. The possible role of neuraminic acid as biological "marker" is discussed.
D001943:Breast Neoplasms / Q000097:blood; D001984:Bronchial Neoplasms / Q000097:blood; D005260:Female; D006689:Hodgkin Disease / Q000097:blood; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood; D008223:Lymphoma / Q000097:blood; D008297:Male; D009369:Neoplasms / Q000097:blood*; D009438:Neuraminic Acids / Q000097:blood*; D012016:Reference Values; D014397:Tuberculosis, Pulmonary / Q000097:blood; D002583:Uterine Cervical Neoplasms / Q000097:blood; D014594:Uterine Neoplasms / Q000097:blood
D009438:Neuraminic Acids
Neuraminsäure-Konzentration im Serum von Tumorpatienten.