Metabolism of phencyclidine by microorganisms.
A number of microorganisms were screened for their ability to metabolize phencyclidine. Two microorganisms, Beauveria sulfurescens and Cunninghamella echinulata, produced hydroxylated metabolites, which were identified as 1-(1-phenylcyclohexyl)-4-hydroxypiperidine and 4-phenyl-4-piperidinocyclohexanol by high-pressure liquid chromatographic analysis.
D001487:Basidiomycota / Q000378:metabolism; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D005285:Fermentation; D005658:Fungi / Q000378:metabolism*; D009090:Mucorales / Q000378:metabolism; D010622:Phencyclidine / Q000378:metabolism*
D010622:Phencyclidine