Changes in free amino acid nitrogen concentration and transaminases in lead treated rats.
Intraperitoneal administration of lead acetate for a period of 4 days in albino rats caused an increase of free amino acid nitrogen level in plasma, liver and kidney. There was diminution of glycogen content in both liver and kidney. The activities of plasma alanine-glutamic transaminase and aspartic-glutamic transaminase were increased with reduction in the activities of alanine-glutamic transaminase and aspartic-glutamic transaminases in liver and kidney.
D000410:Alanine Transaminase / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D007854:Lead / Q000008:administration & dosage*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009584:Nitrogen / Q000378:metabolism*; D009942:Organometallic Compounds; D051381:Rats
D000596:Amino Acids; D009942:Organometallic Compounds; D007854:Lead; D006003:Glycogen; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D009584:Nitrogen; C008261:lead acetate