Total hip replacement in Gaucher's disease.
We performed seven total hip replacements in six patients with the adult form of Gaucher's disease. Excessive perioperative hemorrhage was a common complication, and three patients have required revision of loosened components. Two of these were young patients with a more severe form of the disease. Total hip replacement is feasible and likely to be successful in the older patient with Gaucher's disease and osteonecrosis or failed prior hip surgery.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D005776:Gaucher Disease / Q000150:complications*; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D011183:Postoperative Complications; D011859:Radiography