Potentiation of acrylate ester toxicity by prior treatment with the carboxylesterase inhibitor triorthotolyl phosphate (TOTP).
D000179:Acrylates / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000037:antagonists & inhibitors*; D003408:Cresols / Q000494:pharmacology*; D004357:Drug Synergism; D006868:Hydrolysis; D008297:Male; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism; D014317:Tritolyl Phosphates / Q000494:pharmacology*
D000179:Acrylates; D003408:Cresols; D011506:Proteins; D013438:Sulfhydryl Compounds; D014317:Tritolyl Phosphates; D002265:Carboxylic Ester Hydrolases; C025541:tri-o-cresyl phosphate