A glutamate-activated chloride conductance on a crustacean muscle.
A glutamate-activated inhibitory response on a 'crustacean neuromuscular preparation that receives cholinergic excitatory innervation is described. Glutamate produced a dose-dependent conductance increase to C1-ions. The response was mimicked by ibotenic acid, but not by quisqualic acid, and was blocked by picrotoxin.
D000818:Animals; D002712:Chlorides / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005971:Glutamates / Q000494:pharmacology*; D007051:Ibotenic Acid / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects; D008121:Nephropidae; D009433:Neural Inhibition / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects*; D010852:Picrotoxin / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D002712:Chlorides; D005971:Glutamates; D007051:Ibotenic Acid; D010852:Picrotoxin; D005680:gamma-Aminobutyric Acid