Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver.
D000983:Antipyrine / Q000378:metabolism; D003647:Debrisoquin / Q000378:metabolism*; D006801:Humans; D006900:Hydroxylation; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000378:metabolism*; D008862:Microsomes, Liver / Q000201:enzymology*; D010084:Oxidation-Reduction; D010641:Phenotype
D007546:Isoquinolines; D000983:Antipyrine; D003647:Debrisoquin