Cyclohexyl analogues of some antiinflammatory drugs.
Some new compounds containing cyclohexyl substituents, with a structure similar or analogous to that of traditional antiinflammatory drugs, were synthesized and their antiinflammatory activity was investigated. The strongest activity was shown by alpha-(p-cyclohexylphenyl)-gamma-valerolactone W 8.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis*; D003510:Cyclohexanes / Q000138:chemical synthesis / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
D000893:Anti-Inflammatory Agents; D003510:Cyclohexanes