title: Atenolol pretreatment in fiberoptic bronchoscopy. Effect on cardiac arrhythmias, heart rate and arterial blood pressure.
abstract: Fifty one patients undergoing fiberoptic bronchoscopy were premedicated with atropine and anesthetised with thiopental, nitrous oxide and succinylcholine as a muscle relaxant. Twenty-six patients consisted the control group while twenty-five were given alcohol orally for three consecutive days before the procedure. The treatment group had no cardiac arrhythmias during bronchoscopy while six of the control subjects developed arrhythmias. Heart rate and mean arterial pressure were maintained significantly lower in the treatment group, thus the hypertensive response to tracheal intubation and bronchoscopy was significantly attenuated by atenolol.
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control*; D001262:Atenolol / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D001999:Bronchoscopy / Q000009:adverse effects*; D005260:Female; D005336:Fiber Optic Technology; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*
chemical_list: D011412:Propanolamines; D001262:Atenolol