Angiomorphometry in malignant tumors and inflammatory disease.
Angiographic differentiation of malignant and inflammatory lesions is occasionally impossible, since certain criteria for malignancy also apply to benign lesions. The authors analyzed samples of microangiographic specimens of kidneys with inflammation, tumor, and normal control organs to define mathematically the frequency of such angiographic parameters as caliber fluctuation, vascular avulsion, change of direction and diameter, and change in predominant vascular structure. The described method is transferred to clinical angiograms, and results of both groups are compared. In this preliminary analysis, caliber fluctuation appears to be the single most important criterion for differentiation of malignant and benign angiographic alterations.
D000230:Adenocarcinoma / Q000098:blood supply / Q000000981:diagnostic imaging; D000792:Angiography; D001808:Blood Vessels / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D009393:Nephritis / Q000000981:diagnostic imaging* / Q000473:pathology