TIQs block the development of environment dependent tolerance to ethanol.
D000437:Alcoholism / Q000503:physiopathology; D000818:Animals; D001921:Brain / Q000378:metabolism; D004195:Disease Models, Animal; D004361:Drug Tolerance; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007546:Isoquinolines / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D012890:Sleep / Q000187:drug effects; D019966:Substance-Related Disorders; D044005:Tetrahydroisoquinolines
D007546:Isoquinolines; D044005:Tetrahydroisoquinolines; D000431:Ethanol; C014843:1,2,3,4-tetrahydroisoquinoline