[Chemotherapy of head and neck squamous cell cancer with vindesine (Eldesine) and cis-platinum (Platinex) (author's transl)].
25 patients with advanced head-neck-squamous cell carcinoma were treated with a combination of Vindesine and Cis-Platinum. 12 patients were treated before surgery and/or radiation therapy. 25% achieved complete remission. 13 patients were treated for tumour recurrency after prior surgery and/or radiation therapy. 15% achieved C.R. Vindesine/Cis-Platinum is an alternativ scheme to Bleomycin combinations; even after prior RT and CT tumorreduction is frequent. Prior chemotherapy with following surgery and/or radiation therapy is recommended for the treatment of advanced head and neck tumours.
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D014747:Vinblastine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014751:Vindesine
D014747:Vinblastine; D002945:Cisplatin; D014751:Vindesine
Chemotherapeutische Behandlung von Plattenepithel-Karzinomen im Kopf-Hals-Bereich mit einer Kombination von Vindesine (Eldisine) und Cis-Platin (Platinex).