[The dynamics of the drug release from tablets. Part 6: Liberation of glaucine from Tussiglauzin Dragées (author's transl)].
The liberation of glaucine hydrobromide from Tussiglauzin dragées has been verified. The release to artificial gastric juice was determined by three different procedures: method using the apparatus according to Grzesiczak, stationary-basket method and rotating-basket method. All three methods showed that the largest proportion of the drug (greater than 90%) is released within 2.5 h, the maximum amount determined by means of the rotating-basket method being 99.2%.
D001060:Aporphines; D002626:Chemistry, Pharmaceutical; D004058:Diffusion; D007700:Kinetics; D013607:Tablets
D001060:Aporphines; D013607:Tablets; C005004:glaucine
Dynamik der Arzneimittelabgabe aus Tabletten. 6. Mitteilung: Liberation von Glaucin aus Tussiglauzin-Dragees.