Gastric acid secretion (GAS) and hiatal hernia. I. Relationship between GAS and oesophageal reflux complications.
The relationship between GAS and oesophageal reflux complications in patients with hiatal hernia and incompetent antireflux mechanism is a matter of controversy. In a study of 70 patients operated upon for hiatal hernia, BAO and PAO after betazole stimulation were studied preoperatively in relation to oesophageal reflux complications, age and oesophageal motility. No correlation was found between BAO and oesophageal reflux complications. There was no association between PAO and such complications in patients with oesophageal hypomotility whereas PAO was clearly correlated to these complications in patients with normal oesophageal motility. Oesophageal reflux complications were closely correlated to oesophageal hypomotility and age.
D000328:Adult; D000367:Age Factors; D000368:Aged; D001625:Betazole / Q000494:pharmacology; D004947:Esophagus / Q000503:physiopathology; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000209:etiology; D006548:Hernia, Diaphragmatic / Q000150:complications*; D006551:Hernia, Hiatal / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012636:Secretory Rate / Q000187:drug effects
D001625:Betazole