title: Teratogenic effects of Nicotiana glauca and concentration of anabasine, the suspect teratogen in plant parts.
abstract: Nicotiana glauca consumption by pregnant cows or sows produced arthrogryposis and other congenital deformities in their offspring. The plant material administered contained 0.11% anabasine, the suspect teratogen. But concentration varied among various plant parts; woody material was very low but leaves and bark were high. The anabasine was identified by mass spectral fragmentation analysis.
mesh_terms: D000691:Anabasine / Q000032:analysis*; D000818:Animals; D001176:Arthrogryposis / Q000209:etiology / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology*; D000013:Congenital Abnormalities / Q000662:veterinary*; D005260:Female; D010880:Piperidines / Q000032:analysis*; D010939:Plant Poisoning / Q000150:complications / Q000662:veterinary*; D010947:Plants, Toxic / Q000032:analysis; D011247:Pregnancy; D013552:Swine; D013553:Swine Diseases / Q000209:etiology*; D013723:Teratogens / Q000032:analysis*
chemical_list: D010880:Piperidines; D013723:Teratogens; D000691:Anabasine