title: Bowed fingers. A helpful sign in the early diagnosis of systemic sclerosis.
abstract: Thirteen patients who had in common the clinical finding of shortened forearm flexors were investigated. Additional findings were Raynaud's phenomenon, arthralgia, reduced pulmonary CO diffusion capacity, abnormal EMG, and histological evidence of myopathy. Clinical and serological features in 2 patients were consistent with features described in the mixed connective tissue disease syndrome. The remainder were regarded as having a limited connective tissue disease syndrome, in all probability, a minimal expression of systemic sclerosis. We suggest that the finding of bowed fingers is a more reliable clinical sign than the assessment of skin texture in determining the presence of minimal connective tissue disease.
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000150:complications; D001323:Autoantibodies; D004576:Electromyography; D005260:Female; D005385:Fingers / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008662:Metacarpophalangeal Joint / Q000503:physiopathology; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000150:complications; D009132:Muscles / Q000473:pathology; D011928:Raynaud Disease / Q000150:complications; D012595:Scleroderma, Systemic / Q000150:complications / Q000175:diagnosis*; D012871:Skin Diseases / Q000150:complications
chemical_list: D001323:Autoantibodies