[Drug therapy of mansoni schistosomiasis].
The various presentations of schistosomiasis mansoni are discussed, stressing the indications of parosites elimination. Parasitologic cure is necessary, although, when the infestation is recent (acute), the drug efficacy is lower than in the chronic forms. Surgery may be pertension, special care must be taken, and in the pseudotumoral form there is not enough diet regarding progression of the disease after treatment. Contraindications are linked to associated illness, and are due to toxic effects of the available drugs. The mechanism of action of such drugs are discussed, as well as the historical background. Hycantone, Oxamniquine and Praziquantel are detailed in separate, with the proposed drug schedules and possible side effects.
D005243:Feces / Q000469:parasitology; D006801:Humans; D006826:Hycanthone / Q000627:therapeutic use*; D007546:Isoquinolines / Q000627:therapeutic use*; D009600:Nitroquinolines / Q000627:therapeutic use*; D010073:Oxamniquine / Q000627:therapeutic use*; D011223:Praziquantel / Q000627:therapeutic use*; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000188:drug therapy*; D012556:Schistosomicides / Q000009:adverse effects / Q000494:pharmacology*; D013892:Thioxanthenes / Q000627:therapeutic use*
D007546:Isoquinolines; D009600:Nitroquinolines; D012556:Schistosomicides; D013892:Thioxanthenes; D010073:Oxamniquine; D006826:Hycanthone; D011223:Praziquantel
Tratamento medicamentoso da esquistossomose mansoni.