title: Purification and characterization of a mouse serum glycoprotein increased in level by administration of an antitumor polysaccharide, lentinan.
abstract: One of the three kinds of mouse serum proteins increased in level by the administration of lentinan, designated LA, was found to be ceruloplasmin (p-diphenol:O2:oxidoreductase; EC 1.14.18.1) which contains copper atoms and has amine oxidase activity. This mouse ceruloplasmin is a glycoprotein with a molecular weight of approximately 135,000, and its chemical composition is very similar to that of human ceruloplasmin.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001798:Blood Proteins / Q000032:analysis*; D002570:Ceruloplasmin / Q000032:analysis; D003300:Copper / Q000032:analysis; D005260:Female; D006023:Glycoproteins / Q000032:analysis / Q000097:blood*; D007912:Lentinan / Q000494:pharmacology*; D051379:Mice; D008970:Molecular Weight; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000097:blood; D011134:Polysaccharides / Q000494:pharmacology*
chemical_list: D000596:Amino Acids; D000972:Antineoplastic Agents, Phytogenic; D001798:Blood Proteins; D006023:Glycoproteins; D011134:Polysaccharides; D007912:Lentinan; D003300:Copper; D002570:Ceruloplasmin; D000587:Oxidoreductases Acting on CH-NH Group Donors