A canine model of gastric and colonic polyps.
Polyps were produced in the canine stomach and colon by a surgical technique. In a total of 18 dogs 26 polyps were produced in the stomach or colon. Twenty of the 26 polyps were viable when endoscopically and microscopically examined. Polyps of approximately 1 cm in diameter and 3 to 4 cm in length can be produced without sloughing. The gross and microscopic characteristics of the canine polyp are quite similar to the human condition. Obviously the adenomatous tissue of the polyp head was not reproduced, but this area is not generally cut during polypectomy. The surgical produced polyps appear to be useful as a model to study the effects of electrosurgical cutting and for training in the technique of polypectomy.
D000818:Animals; D003110:Colonic Neoplasms / Q000473:pathology; D004195:Disease Models, Animal; D004285:Dogs; D004598:Electrosurgery; D007417:Intestinal Polyps / Q000473:pathology; D008722:Methods; D011127:Polyps / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology