Response to transient haemorrhage after acute and chronic section of the carotid sinus nerves.
Adaptation to denervation of the carotid sinus region was studied on cats during hypotension induced by a controlled haemorrhage. After denervation, the fall in arterial pressure in response to haemorrhage was increased, but rhe partial recovery of blood pressure was preserved. In chronic animals, this pattern of response was also seen, but a resting hypertension developed and ensured that the minimal blood pressure and the recovery reached during the haemorrhage were similar to those of intact animals. The studies suggest that the primary role of the carotid receptors is to minimize the effect of stresses which lead to hypotension, rather than to set the level of the resting blood pressure.
D000818:Animals; D001012:Aorta, Abdominal / Q000502:physiology; D001794:Blood Pressure; D002346:Carotid Sinus / Q000502:physiology*; D002415:Cats; D003714:Denervation; D006470:Hemorrhage / Q000503:physiopathology*; D012146:Rest