title: Metabolic neural mapping in neonatal rats.
abstract: Functional neural mapping by 14C-deoxyglucose autoradiography in adult rats has shown that increases in neural metabolic rate that are coupled to increased neurophysiological activity are more evident in axon terminals and dendrites than neuron cell bodies. Regions containing architectonically well-defined concentrations of terminals and dendrites (neuropil) have high metabolic rates when the neuropil is physiologically active. In neonatal rats, however, we find that regions containing well-defined groupings of neuron cell bodies have high metabolic rates in 14C-deoxyglucose autoradiograms. The striking difference between the morphological appearance of 14C-deoxyglucose autoradiograms obtained from neonatal and adult rats is probably related to developmental changes in morphometric features of differentiating neurons, as well as associated changes in type and locus of neural work performed.
mesh_terms: D020155:3-Hydroxybutyric Acid; D000818:Animals; D000831:Animals, Newborn; D001345:Autoradiography; D001921:Brain / Q000378:metabolism*; D002250:Carbon Radioisotopes; D002540:Cerebral Cortex / Q000378:metabolism; D003847:Deoxyglucose / Q000378:metabolism; D006885:Hydroxybutyrates / Q000378:metabolism; D007700:Kinetics; D009474:Neurons / Q000378:metabolism*; D051381:Rats
chemical_list: D002250:Carbon Radioisotopes; D006885:Hydroxybutyrates; D003847:Deoxyglucose; D020155:3-Hydroxybutyric Acid