Clearance of intravenously injected colloidal carbon from peripheral blood in mice, rats, rabbits and dogs.
The clearance of intravenously injected colloidal carbon from the peripheral blood was investigated in mice, rats, rabbits and dogs. The blood clearance of carbon was more rapid in the young than in the old for all the species examined. A biphasic clearance curve was observed in the dogs of all age groups tested, and in the rabbits of 8 and 16 weeks old. The rate of colloidal carbon clearance was slower in the rabbits than in other three species.
D000375:Aging; D000818:Animals; D002244:Carbon; D003102:Colloids / Q000008:administration & dosage / Q000378:metabolism*; D004285:Dogs; D007275:Injections, Intravenous; D051379:Mice; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
D003102:Colloids; D002244:Carbon