[The age-dependent influence of diet on lipid metabolism (author's transl)].
In contrast to 3 months old rats of the Wistar strain show 18 months old animals an elevation of the serum triglyceride level under the conditions of a sucrose diet (25% of the energy uptake). Clinical investigations with women show a similar age difference. These results may not be explained by the age-dependent behavior of the activity of several lipogenic enzymes of liver and adipose tissue and of their adaptation to a sucrose diet, but the age-dependent decrease of the lipoprotein lipase activity may be of special importance.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000818:Animals; D002784:Cholesterol / Q000097:blood; D004040:Dietary Carbohydrates; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D050356:Lipid Metabolism; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008292:Malate Synthase / Q000378:metabolism; D008875:Middle Aged; D051381:Rats; D014280:Triglycerides / Q000097:blood
D004040:Dietary Carbohydrates; D014280:Triglycerides; D006493:Heparin; D002784:Cholesterol; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D008292:Malate Synthase; D008071:Lipoprotein Lipase
Zur Molekularbiologie des Alterns. 21. Mitteilung. Alimentäre Beeinflussung des Lipidstoffwechsels in Abhängigkeit vom Alter.