title: Contact urticaria from nickel and plastic additives (butylhydroxytoluene, oleylamide).
abstract: In two patients urticaria was elicited by contact with nickel-containing objects. Chamber-prick test with nickel sulfate 2.5% in pet. evoked a strong urticarial reaction in both patients. In one of the patients contact with plastic articles also provoked urticaria. A 20-min patch test with several articles of plastic (polyethylene and PVC) and with butylhydroxytoluene (BHT) 1% in ethanol elicited urticarial reactions. BHT is used as an antioxidant in plastic. Furthermore, open patch test with oleylamide (amide of oleic acid) 0.1% in ethanol elicited a strong urticarial reaction in 20 min. This chemical is used as a slipping agent in plastic.
mesh_terms: D000328:Adult; D002084:Butylated Hydroxytoluene / Q000009:adverse effects*; D004485:Eczema / Q000139:chemically induced; D005260:Female; D006801:Humans; D009532:Nickel / Q000009:adverse effects*; D009829:Oleic Acids / Q000009:adverse effects*; D010969:Plastics / Q000009:adverse effects; D014581:Urticaria / Q000139:chemically induced*
chemical_list: D009829:Oleic Acids; D010969:Plastics; D002084:Butylated Hydroxytoluene; C029407:oleylamide; D009532:Nickel