The effect of skim milk, yoghurt, and full cream milk on human serum lipids.
The hypothesis that certain milk products contain a cholesterol-lowering "milk factor" was tested in adolescent schoolboys whose diets were complemented with 2 L of skim milk, yoghurt, or full cream milk daily for 3 wk. After a fall in all serum lipids during the precomplementation wk, serum total cholesterol and low-density lipoprotein cholesterol continued to fall on skim milk; in contrast, it rose for the first 2 wk on yoghurt or full cream milk. These changes correlated with dietary fat and cholesterol intakes. Total cholesterol returned to base-line values during the 3rd wk on yoghurt or full cream milk. High-density lipoprotein cholesterol and percentage high-density lipoprotein/total cholesterol rose transiently in all three groups, with the highest levels being recorded on full cream milk. Serum triglycerides tended to decrease in all groups. No convincing evidence of a milk factor could be found, but skim milk appeared to have a cholesterol-lowering effect at least partly due to its low lipid content.
D000293:Adolescent; D000818:Animals; D000924:Anticholesteremic Agents; D002417:Cattle; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL; D003611:Dairy Products / Q000032:analysis; D004041:Dietary Fats / Q000008:administration & dosage* / Q000032:analysis; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008892:Milk / Q000032:analysis; D013997:Time Factors; D014280:Triglycerides / Q000097:blood; D015014:Yogurt / Q000032:analysis
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D004041:Dietary Fats; D008055:Lipids; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol