title: Quantitative histological studies on the spleen of ducks after neonatal thymectomy and bursectomy.
abstract: The duck spleen was examined histoplanimetrically after neonatal surgical thymectomy, cyclophosphamide treatment, and/or X-ray irradiation. The development of the periarterial lymphoid tissues, which consisted mainly of small lymphocytes, was inhibited in the spleen of the Tx and Tx-X ducks. The peri-ellipsoidal lymphoid tissues, consisting of pyroninophilic medium or large sized lymphocytes, was greatly depleted in the Bx and/or CY ducks. The germinal centres also showed probable bursa dependency. On the other hand, the development of the perivenous lymphoid tissue was not inhibited after Tx and Bx. A number of plasma cells was distributed in the red pulp of the Bx and/or CY duck spleen.
mesh_terms: D000818:Animals; D002060:Bursa of Fabricius / Q000502:physiology*; D002452:Cell Count; D003520:Cyclophosphamide / Q000494:pharmacology; D004372:Ducks / Q000033:anatomy & histology*; D008214:Lymphocytes; D009929:Organ Size; D010950:Plasma Cells; D013154:Spleen / Q000166:cytology* / Q000187:drug effects / Q000528:radiation effects; D013934:Thymectomy
chemical_list: D003520:Cyclophosphamide