title: Cerebellar atrophy in epilepsy and headache: lack of relationship to phenytoin.
abstract: CT scans of 70 patients with seizures and 48 patients with headaches were studied. Using accepted CT criteria for the diagnosis of cerebellar atrophy, the films were analyzed in a blind, unbiased fashion to evaluate possible relationship between cerebellar atrophy and phenytoin use or epilepsy itself. We found no evidence that either phenytoin or epilepsy caused cerebellar atrophy.
mesh_terms: D000293:Adolescent; D000328:Adult; D001284:Atrophy; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology*; D004827:Epilepsy / Q000473:pathology*; D005260:Female; D006261:Headache / Q000473:pathology*; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D010672:Phenytoin