title: Biochemical polymorphism in the rat: genetics of three electrophoretic variants and characterization of inbred strains.
abstract: Nine inbred strains of the rat (Rattus norvegicus) were screened for differences in electrophoretically detectable proteins. Interstrain variation was observed for 7 of 26 proteins. Three of these variants have not been described previously: leucine aminopeptidase (Lap-1), major urinary protein (Mup-1), and seminal vesicle protein (Svp-2). Genetic analysis revealed two autosomal alleles for each of these polymorphisms. The loci Lap=1, Mup-1, and Svp-2 are linked neither to one another nor to the previously described Svp-1 and Es-4 loci. Each of the nine strains can be identified now by a specific set of monogenic markers.
mesh_terms: D000818:Animals; D004798:Enzymes / Q000235:genetics; D008040:Genetic Linkage; D014644:Genetic Variation; D007931:Leucyl Aminopeptidase / Q000235:genetics; D008297:Male; D011110:Polymorphism, Genetic; D029584:Prostatic Secretory Proteins; D011506:Proteins / Q000235:genetics; D011507:Proteinuria; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D029589:Seminal Plasma Proteins; D012669:Seminal Vesicles / Q000032:analysis
chemical_list: D004798:Enzymes; D029584:Prostatic Secretory Proteins; D011506:Proteins; D029589:Seminal Plasma Proteins; C043076:beta-microseminoprotein; D007931:Leucyl Aminopeptidase