The haemostatic system components of neointima forming in polyester aortic grafts in the early postoperative period.
The aim of the studies was to determine the content of certain components of the haemostatic system in the neointima of a polyester graft implanted in the dog abdominal aorta over a 7-day period of observation. The neointima of an aortic polyester graft in the early postoperative period possesses a high thromboplastic activity, greater than that of the artery or vein, and containing prothrombin, active thrombin, platelet aggregating substances and heparin neutralizing substances. The plasminogen activator activity in the neointima of the polyester graft is also considerably higher than in the intima of arteries and veins.
D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery*; D001158:Arteries / Q000032:analysis / Q000201:enzymology; D001777:Blood Coagulation; D001807:Blood Vessel Prosthesis; D004285:Dogs; D008297:Male; D010960:Plasminogen Activators / Q000096:biosynthesis; D010974:Platelet Aggregation; D010978:Platelet Factor 4 / Q000096:biosynthesis; D011091:Polyesters / Q000627:therapeutic use*; D011184:Postoperative Period; D011516:Prothrombin / Q000096:biosynthesis; D013917:Thrombin / Q000096:biosynthesis; D013925:Thromboplastin / Q000096:biosynthesis; D014680:Veins / Q000032:analysis / Q000201:enzymology
D011091:Polyesters; D010978:Platelet Factor 4; D011516:Prothrombin; D013925:Thromboplastin; D010960:Plasminogen Activators; D013917:Thrombin