title: Investigations into some pharmacological actions of ergometrine.
abstract: In contrast to the classical dopaminergic agonist, Eg did not stimulate ACh output from the cerebral cortex of anaesthetized rat. The effect of the drug on guinea-pig and rat vas deferens was mediated by alpha-adrenoceptors and the same is true for arterial blood pressure of rats. In the cardiovascular system of guinea-pig Eg behaved like Histamine.
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D004874:Ergonovine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D006168:Guinea Pigs; D008297:Male; D051381:Rats; D014649:Vas Deferens / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000109:Acetylcholine; D004874:Ergonovine