[Detection and identification of irregular anti-erythrocyte antibodies with the Groupamatic G 360. Adaptation to the routine].
The screening of irregular red-cell antibodies on 20.200 recipient samples was carried out simultaneously on continuous flux AUTO-ANALYZER (LIP-bromeline) and GROUPAMATIC (TPC-bromeline). From results it appears: --an equivalent sensibility of both technologies to detect Rh, Kell, Duffy and Kidd antibodies; --a higher sensibility of Groupamatic to detect particularly Lewis and P1 antibodies; --a clear superiority of TPC compared to bromeline technique which is commonly used with Groupamatic. Small modifications of the standard TPC system allow to associate, in routine work, detection of irregular red-cell antibodies with other analyses, such as ABO Rh grouping and phenotyping. From this last point of view, a restricted test of coagglutination phenotyping has revealed to be very promising.
D000906:Antibodies / Q000032:analysis*; D001322:Autoanalysis / Q000295:instrumentation*; D001788:Blood Grouping and Crossmatching / Q000295:instrumentation*; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans
D000906:Antibodies
Dépistage et identification des anticorps irréguliers antiérythrocytaires sur Groupamatic G 360. Adaptation à la routine.