The effects of severe thermal injury on the glycosaminoglycans of guinea pig skin.
The central purpose of the present investigation was the qualitatively and quantitatively analyze the glycosaminoglycans of guinea pig skin at 2 hr after a third-degree burn injury. The data obtained from uronic acid determinations, fractionation by column chromatography and cellulose acetate electrophoresis indicate no significant alterations in the glycosaminoglycans at 2 hr postburn. The data presented in this study support the concept that the glycosaminoglycans are not immediately damaged by the heat of the burn.
D000818:Animals; D002056:Burns / Q000378:metabolism*; D002845:Chromatography; D004588:Electrophoresis, Cellulose Acetate; D006025:Glycosaminoglycans / Q000032:analysis*; D006168:Guinea Pigs; D006909:Hydroxyproline / Q000032:analysis; D008297:Male; D012867:Skin / Q000032:analysis*; D014574:Uronic Acids / Q000032:analysis
D006025:Glycosaminoglycans; D014574:Uronic Acids; D006909:Hydroxyproline