title: [The effect of tiofedrine on brain perfusion in patients with cerebrovascular insufficiency].
abstract: The influence of intravenous tinofedrine (0.12 to 0.17 mg/kg body-weight) on cerebral blood flow has been investigated in 23 patients (mean age 65 years) with subacute cerebral infarction. The mean cerebral blood flow increased significantly by 20% in the infarcted hemisphere during a treatment period of 12 days. Clinically an improvement of an initially depressed vigilance level was established which was quantified psychopathometrically in 4 patients.
mesh_terms: D000368:Aged; D002544:Cerebral Infarction / Q000188:drug therapy*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D013876:Thiophenes / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D013876:Thiophenes; C018159:tinofedrine
vernacular_title: Die Wirkung von Tinofedrin auf die Hirndurchblutung bei Patienten mit zerebrovaskulärer Insufffizienz.