[A clinicopathological study on microinvasive carcinoma (stage Ia) of the uterine cervix (author's transl)].
A pathological study of 142 cases of stage I carcinoma of the uterine cervix with a depth of invasion of less than 5 mm showed 119 of them, 104 stage Ia (87.4%) and 15 stage Ib (12.6%), to have a depth of invasion of less than 3 mm. As to the histological pattern of invasion in stage Ia, advanced bulky outgrowth from glands and early stromal invasion were observed at nearly the same frequency. Of 15 cases of stage Ib cervical carcinoma with depth of invasion of less than 3 mm, 10 were of reticular invasion, 4 were of "frühe Stroma-arrosion" and 1 was of vessel permeation. With either pattern of invasion, annular and longitudinal extension of the lesion tended to be wider in stage Ib than in stage Ia. Spread to the ectocervix was also wider in stage Ib. Modalities of treatment used for stage Ia carcinoma of the cervix were extended radical hysterectomy in 28 cases, sub-extended hysterectomy in 68 cases, simple hysterectomy in 3 cases, conization in 1 case and radiotherapy in 4 cases. Lymph node metastasis was noted in none of stage I cervical cancer cases with a radiotherapy in 4 cases. Lymph node metastasis was noted in none of stage I cervical cancer cases with a depth of invasion of less than 5 mm.
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000473:pathology*