title: Tracheobronchial mucus: abnormalities related to asthma and its treatment.
abstract: The presence of mucociliary dysfunction in bronchial asthma is suggested by clinical observations and has been confirmed by pathologic and physiologic studies. Since mucociliary dysfunction may play a considerable role in the pathophysiology of bronchial asthma, currently available therapeutic measures which enhance mucous transport should be included in the treatment plan. It is expected that a better understanding of the underlying mechanisms will ultimately result in the development of more potent pharmacologic agents capable of improving abnormal mucociliary function.
mesh_terms: D000402:Airway Obstruction / Q000503:physiopathology; D000818:Animals; D001249:Asthma / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D001692:Biological Transport; D001980:Bronchi / Q000503:physiopathology*; D002923:Cilia / Q000502:physiology / Q000503:physiopathology; D003251:Constriction, Pathologic; D006801:Humans; D009093:Mucus / Q000502:physiology; D014132:Trachea / Q000503:physiopathology*