title: Benign macro-orchidism in a pubescent boy.
abstract: We report on a 12 1/2-year-old boy with bilateral testicular enlargement. After an extensive evaluation we eliminated precocious puberty, hypothyroidism, congenital adrenal hyperplasia, X-linked mental retardation and bilateral malignant testicular neoplasms from consideration. Diagnosis was benign macro-orchidism. The clinical and laboratory features of this condition are sufficiently distinct from the other causes of testicular enlargement to allow a diagnosis to be made without testicular biopsy or orchiectomy.
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006728:Hormones / Q000097:blood; D006801:Humans; D006984:Hypertrophy; D008297:Male; D013733:Testicular Diseases / Q000175:diagnosis; D013737:Testis / Q000473:pathology*
chemical_list: D006728:Hormones