[Granulomatous placentitis in toxoplasmosis (author's transl)].
A case is reported of granulomatous placentitis due to Toxoplasma infection, which led, like two similar cases reported in the literature to abortion within the first half of pregnancy. The author tries to interpret the pathogenesis of this rare type of reaction. In view of the early onset of infection a complete immune response of the fetus in this state of development appears unlikely. The question arises whether maternal immuno-competent cells might be responsible for this mature immune reaction, which took the form of granulomatous inflammation of the placenta. A prerequisite for this type of reaction is considered to be prolonged retention of vital placental tissue in the uterus in intra-uterine death of the fetus or complete abortion.
D000022:Abortion, Spontaneous / Q000473:pathology; D000328:Adult; D005260:Female; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006801:Humans; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D014123:Toxoplasmosis / Q000473:pathology*
Granulomatöse Plazentitis bei Toxoplasmose.