Variation of urinary melatonin excretion in humans during the first 30 years of life.
Urinary melatonin variation in humans were demonstrated to be a function of age. A radioimmunological assay was used. The values obtained, expressed as nmol x 24 h-1 x kg-1, progressively decreased from birth onwards, with a more accentuated and momentary inflection at the moment of the genital crisis in newborns and at puberty. The results obtained concern only melatonin and not its metabolites, as a result of the high specificity of the antibodies employed.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000652:urine; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007700:Kinetics; D008550:Melatonin / Q000652:urine*
D003404:Creatinine; D008550:Melatonin