title: [On the question of interval application of topical corticoids/Practicability and efficacy (author's transl)].
abstract: Therapeutic efficacy and practicability of an interval treatment were investigated in a multi-center study in a total of 1573 patients with psoriasis or eczema, respectively. Fluocortolone monohydrate as Syracort and Syracerin as steroid-free "partner drug" were applied at 4-13-day intervals. The findings and established results substantiate equivalent therapeutic success in comparison with consistent treatment. Starting from the premise that the risk of steroid-induced skin lesions can be reduced, if not avoided, by interval application of topical corticoids one may consider steroid application at intervals as superior to consistent therapy.
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004485:Eczema / Q000188:drug therapy; D005448:Fluocortolone / Q000008:administration & dosage / Q000627:therapeutic use; D005938:Glucocorticoids; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D005448:Fluocortolone
vernacular_title: Zur Frage einer periodisierten Anwendung topischer Corticoide. Praktikabilitäat und Wirksamkeit.