[Interaction of cholesterol with apoprotein E - an arginine-rich protein of very low density lipoproteins].
Apoprotein E was isolated from delipidated lipoproteins of very low density obtained from blood plasma of rabbits with experimental hypercholesterinemia. The protein, whose molecular weight is 45000, produces a single hand during polyacrylamide gel electrophoresis and contains 10% of arginine. The formation of an apoprotein E -- cholesterol complex and participation of guanidine groups of guanidine groups of arginine residues of apoprotein E in cholesterol binding have been postulated.
D000818:Animals; D001053:Apolipoproteins / Q000097:blood; D002784:Cholesterol; D008079:Lipoproteins, VLDL / Q000097:blood; D008970:Molecular Weight; D011485:Protein Binding; D011817:Rabbits
D001053:Apolipoproteins; D008079:Lipoproteins, VLDL; D002784:Cholesterol
Vzamideĭstvie kholesterina a apoproteinom E - argininbogatym belkom lipoproteidov ochen' nizkoĭ plotnosti.