title: Bone formation and impedance of electrical current flow.
abstract: The impedance to current flow to an electrically stimulated cathode did not change appreciably over a 12-week measurement period and did not support the hypothesis of a temporal relationship between bone formation and impedance to current flow in the region of the cathode. The use of an electrically stimulated titanium cathode at a current density of 0.33 microA/mm2 in this model of canine delayed union resulted in a significant bone formation when analyzed by quantitative and qualitative methods. Sequential quantitative radionuclide scanning correlated well with histologic appearance of bone formation and was a sensitive indicator of electrically induced osteogenesis.
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D004285:Dogs; D004553:Electric Conductivity; D004558:Electric Stimulation; D004566:Electrodes; D010012:Osteogenesis; D013977:Tibia / Q000502:physiology; D013997:Time Factors; D014025:Titanium
chemical_list: D014025:Titanium