Glycosylated haemoglobin levels in a colony of spontaneously diabetic rabbits.
Elevated glycosylated haemoglobin values have been observed in overtly diabetic animals from a colony of spontaneously diabetic rabbits. Chemically diabetic and normal animals did not show elevated levels. Overtly diabetic animals averaged 12.2% glycosylated haemoglobin versus 4.3% for chemically diabetic and 3.9% for normal animals. Increased levels did not correlate with plasma glucose concentration. Some chemically diabetic and normal animals progressed with time to a more severe diabetic classification. Glycosylated haemoglobin levels at the high end of the range of values for normal animals are predictive of this progression especially in certain litters.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood / Q000662:veterinary*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D006027:Glycosides / Q000032:analysis*; D006441:Hemoglobin A / Q000031:analogs & derivatives* / Q000032:analysis; D011817:Rabbits; D012016:Reference Values
D001786:Blood Glucose; D006027:Glycosides; D006441:Hemoglobin A