title: Chromosome variants in children referred for cytogenetic examination from two paediatric departments during a 12-year-period.
abstract: The present study deals with frequency and clinical signs of children with chromosome variants. Previous studies of the possible effect of different chromosome variants on phenotype and risk of congenital abnormalities are controversial.
mesh_terms: D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D002877:Chromosomes, Human / Q000648:ultrastructure*; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D007621:Karyotyping; D008297:Male; D010641:Phenotype; D012189:Retrospective Studies