Medical treatment of chronic hepatitis. Results of a retrospective study.
A retrospective study on 247 cases of chronic hepatitis was made. 177 patients with chronic aggressive hepatitis (CAH) were treated with prednisolone, azathioprine, the combination of prednisolone and azathioprine, or D-penicillamine. Prednisolone and the combined therapy was significantly more effective than azathioprine or D-penicillamine. It seems questionable, however, whether the addition of azathioprine to prednisolone is of real advantage.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006505:Hepatitis / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010396:Penicillamine / Q000008:administration & dosage / Q000627:therapeutic use*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies
D011239:Prednisolone; D010396:Penicillamine; D001379:Azathioprine