Changes in thyroid hormones in obese women following jejuno-ileal bypass surgery.
The serum concentrations of thyroxine (T4), 3,5,3'-triiodothyronine (T3) and 3,3'5'-triiodothyronine (reverse T3) in 10 massively obese women were studied before and at intervals for one year after jejuno-ileal bypass operation. A significant rise in T3 (P less than 0.01) over the immediately preoperative value, a significant fall in rT3 (P less than 0.01) but no significant change in T4 was found during the post-recovery follow-up period. It is concluded that maintaining a relatively high T3 level following jejuno-ileal bypass surgery may contribute to the substantial weight reduction achieved by patients after this operation.
D000328:Adult; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000628:therapy*; D013963:Thyroid Hormones / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014285:Triiodothyronine, Reverse / Q000097:blood
D013963:Thyroid Hormones; D014284:Triiodothyronine; D014285:Triiodothyronine, Reverse; D013974:Thyroxine