title: Epileptic discharges produced in monkeys by injection of spleen cells from rabbits immunised with monkey brain.
abstract: Cell suspension from the spleen of rabbits immunised with monkey brain gave rise to epileptic discharges in the monkey when injected intracortically, except in the case of one injection from a rabbit not recently given a booster treatment. In contrast, cell suspensions from the spleen of unimmunised rabbits, or of a rabbit immunised with a non-brain material, in all cases failed to be effective. The epileptic discharges began about 2 weeks after injection, were variable in frequency, and lasted throughout the period of recording.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D002540:Cerebral Cortex / Q000276:immunology; D005071:Evoked Potentials; D007106:Immune Sera / Q000276:immunology*; D008253:Macaca mulatta; D011817:Rabbits; D012640:Seizures / Q000276:immunology*; D013154:Spleen / Q000276:immunology*
chemical_list: D007106:Immune Sera