Decrease of thyroid antibodies during pregnancy.
The behavior of serum anti-thyroglobulin (Abs-Tg) and antimicrosomal antibodies (Abs-Mc) was examined during and after normal pregnancies. The antibodies titer decreases as pregnancy progresses; they cross the placenta and are present in the fetal serum. Infants' thyroid function is not affected by this transplacentar transfer. The Abs-Tg titer increases again after delivery.
D000328:Adult; D001323:Autoantibodies / Q000276:immunology*; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D008861:Microsomes / Q000276:immunology*; D011247:Pregnancy; D013954:Thyroglobulin / Q000276:immunology*
D001323:Autoantibodies; D013954:Thyroglobulin