Epiglottic enlargement following radiation treatment of head and neck tumors.
This article describes delayed noninfectious epiglottic enlargement in two children, one with rhabdomyosarcoma of nasopharynx and the other with undifferentiated anaplastic carcinoma of the neck. The pathogenesis is assumed to be delayed laryngeal injury following radiotherapy alone or combined with chemotherapy. The radiographic findings in these cases were identical to those of acute epiglottitis.
D000293:Adolescent; D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy; D002648:Child; D004825:Epiglottis / Q000528:radiation effects*; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology*; D012208:Rhabdomyosarcoma / Q000188:drug therapy / Q000532:radiotherapy