title: The effects of severe thermal injury on the glycosaminoglycans of guinea pig skin.
abstract: The central purpose of the present investigation was the qualitatively and quantitatively analyze the glycosaminoglycans of guinea pig skin at 2 hr after a third-degree burn injury. The data obtained from uronic acid determinations, fractionation by column chromatography and cellulose acetate electrophoresis indicate no significant alterations in the glycosaminoglycans at 2 hr postburn. The data presented in this study support the concept that the glycosaminoglycans are not immediately damaged by the heat of the burn.
mesh_terms: D000818:Animals; D002056:Burns / Q000378:metabolism*; D002845:Chromatography; D004588:Electrophoresis, Cellulose Acetate; D006025:Glycosaminoglycans / Q000032:analysis*; D006168:Guinea Pigs; D006909:Hydroxyproline / Q000032:analysis; D008297:Male; D012867:Skin / Q000032:analysis*; D014574:Uronic Acids / Q000032:analysis
chemical_list: D006025:Glycosaminoglycans; D014574:Uronic Acids; D006909:Hydroxyproline