Pharmacotherapeutics of newer penicillins and cephalosporins.
The beta-lactam group of compounds includes a large number of biologically active substances. Some are important as antibiotics (penicillin and cephalosporins) or antibiotic precursors (6-aminopenicillanic acid) and some are important due to their inhibitory action on several beta-lactamases. The pharmacologic features of these compounds are discussed on the basis of their structure, mechanism of action, pharmacokinetics, therapeutics, toxicologic properties, interaction, and incompatibilities.
D000818:Animals; D002511:Cephalosporins / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D004232:Diuretics / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D010406:Penicillins / Q000494:pharmacology* / Q000627:therapeutic use; D011485:Protein Binding
D002511:Cephalosporins; D004232:Diuretics; D010406:Penicillins