title: The lactate dehydrogenase activity and isoenzyme pattern of normal and hypokinetic human tendons.
abstract: The LDH specific activity and the LDH isoenzyme pattern of eleven pairs of different normal tendons were compared with hypokinetic tendons. The LDH specific activity of hypokinetic tendons was 13--66% of the specific activity of normal tendons. The isoenzyme pattern of hypokinetic tendons altered in such a way that--with one exception--the ratio of LDH-5 and LDH-4 decreased and the ratio of LDH-1, LDH-2, and LDH-3 increased and, as a consequence, the amount of the M subunit decreased.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000201:enzymology*; D013710:Tendons / Q000201:enzymology*; D014018:Tissue Distribution
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase