A comparison of dopamine receptor blocking assay with plasma drug levels of haloperidol in schizophrenic patients.
A comparison of a chemical analytic technique (gas chromatography/mass spectrometry) with that of the dopamine receptor blocking assay in a study involving seven schizophrenic patients being administered a fixed dosage of haloperidol (20 mg) demonstrated a high degree of correspondence in the quantification of the plasma levels of the neuroleptic.
D000328:Adult; D002849:Chromatography, Gas; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000097:blood*; D006801:Humans; D008297:Male; D013058:Mass Spectrometry; D008875:Middle Aged; D011954:Receptors, Dopamine / Q000187:drug effects*; D012559:Schizophrenia / Q000097:blood* / Q000188:drug therapy; D013997:Time Factors
D011954:Receptors, Dopamine; D006220:Haloperidol