[Carbon 13 nuclear magnetic resonance conformation studies of peptides with analgesic activity].
13C Nuclear magnetic resonance studies of proline peptides with central antalgic activity (Pro-Arg, Arg-Pro, Pro-Arg-Pro, Pro-Lys-Pro) indicate a predominance of trans conformation at all pH values; but their physiological activities appear to be related to the ability of the C-terminal proline peptides to assume the cis conformation.
D000700:Analgesics / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D009842:Oligopeptides / Q000032:analysis*; D011392:Proline / Q000032:analysis*; D011487:Protein Conformation
D000700:Analgesics; D009842:Oligopeptides; D011392:Proline
Etude conformationnelle par résonance magnétique nucléaire du carbone 13 de peptides à activité antalgique.