Comparative study of reticuloendothelial system pools of the normal and immunologically activated rabbit synovium with radiocolloids.
A quantitative study of the uptake of radiocolloids by the joint synovium relative to other reticuloendothelial system organs was performed in the rabbit model. The radiocolloids of 198Au and 99mTc-sulfide colloid were administered intravenously and distribution in synovial pad, liver, spleen, bone marrow, blood, lung, and other tissues was determined in a gamma counter. The uptake of radiocolloids by both normal and immunologically activated synovial pad was very small in comparison with the reticuloendothelial cells in liver, spleen, and bone marrow.
D000818:Animals; D007275:Injections, Intravenous; D012157:Mononuclear Phagocyte System / Q000032:analysis*; D011817:Rabbits; D013455:Sulfur / Q000008:administration & dosage* / Q000032:analysis; D013583:Synovial Membrane / Q000032:analysis / Q000276:immunology*; D013667:Technetium / Q000008:administration & dosage* / Q000032:analysis; D013671:Technetium Tc 99m Sulfur Colloid
D013671:Technetium Tc 99m Sulfur Colloid; D013455:Sulfur; D013667:Technetium