Excessive hypertriglyceridemia and pancreatitis in pregnancy. Association with deficiency of lipoprotein lipase.
Acute pancreatitis verified at laparotomy occurred in the 37th week in 1 of 4 women who developed excessive hypertriglyceridemia (type V hyperlipoproteinemia) during pregnancy. The hypertriglyceridemia was associated with and possibly caused by deficiency of lipoprotein lipase, measured as the NaCl sensitive component of post-heparin lipase activity. A severely fat-restricted diet controlled the hypertriglyceridemia in 1 of the patients, followed during a second pregnancy.
D000328:Adult; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D006954:Hyperlipoproteinemia Type V / Q000097:blood*; D007231:Infant, Newborn; D008071:Lipoprotein Lipase / Q000172:deficiency*; D008297:Male; D010195:Pancreatitis / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides; D002784:Cholesterol; D008071:Lipoprotein Lipase