Involvement of radical species in the oxidation of aminopyrine and 4-aminoantipyrine by cumene hydroperoxide in rat liver microsomes.
D000632:Aminopyrine / Q000378:metabolism*; D000675:Ampyrone / Q000378:metabolism*; D000818:Animals; D000983:Antipyrine / Q000031:analogs & derivatives*; D001555:Benzene Derivatives / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005609:Free Radicals; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008797:Metyrapone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000378:metabolism*; D010084:Oxidation-Reduction; D010545:Peroxides / Q000494:pharmacology*; D051381:Rats
D001555:Benzene Derivatives; D005609:Free Radicals; D010545:Peroxides; D000632:Aminopyrine; D000675:Ampyrone; D003577:Cytochrome P-450 Enzyme System; C007164:cumene hydroperoxide; D000983:Antipyrine; D008797:Metyrapone