title: [10 years - investigations of lipid-metabolism-parameters in the longitudinal study of Leipzig (author's transl)].
abstract: As part of the longitudinal gerontological study conducted in Leipzig, cholesterol and the fatty acid spectrum in the serum were determined (by gas chromatography) in 158 cases (46 men, 112 women) at intervals between 2 and 4 years over the period from 1968 to 1978. During the 10-year period the statistical values showed a definite increase in the percentage of cholesterol and linoleic acid. As a result of the significant decrease in the palmitic acid values, the saturated fatty acid percentages as a whole dropped despite an increase in stearic acid. The general trend was toward the elimination of differences between men and women and overweight persons and those with normal weights. There were definite correlations between a reduction in relative weight and a drop or reduced increase of cholesterol on the one hand an increase in linoleic acid on the other. This is most probably due to the fat-reduced and -modified diet to which especially the older test persons changes over during the 10-year period. This diet contained many polyene fatty acids. The changeover can therefore be suspected to lead to antiatherogenic fatty acid constellations in the serum.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D008041:Linoleic Acids / Q000097:blood; D008055:Lipids / Q000097:blood*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged
chemical_list: D005230:Fatty Acids, Nonesterified; D008041:Linoleic Acids; D008055:Lipids; D002784:Cholesterol
vernacular_title: 10-Jahres-Beobachtungen von Fettstoffwechselparametern in der Leipziger Längsschnittstudie.