[Use of a synchronous Chlorella population for studying the effect of low-dose stimulation of N-Ninitroso-N-methylurea].
The cycle of Chlorella cells development is shortened under the action of NMU. The effect of stimulation is dependent on the cell developmental stage at the time of treatment with the mutagen. This effect is absent in cells being at the first and final stages of the development. The maximum stimulation is observed after treatment of the 14 hours old culture (the mutagen concentration being 35.10(-7) M) and proceeds during several generations.
D002453:Cell Cycle / Q000187:drug effects; D002708:Chlorella / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008770:Methylnitrosourea / Q000494:pharmacology*; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013997:Time Factors
D009607:Nitrosourea Compounds; D008770:Methylnitrosourea
Ispol'zovanie sinkhronnoĭ populiatsii khlorelly dlia izucheniia éffekta stimuliatsii nizkimi dozami N-nitrozo-N-metilmocheviny.