Metabolism of C-terminal pentapeptide of gastrin in the rat. Part IV. Catabolic pathways of the N-terminal BOC-14C-glycine fragment.
The catabolism of the 14C-labelled pentagastrin was investigated in rats. The following results were found: -- the labelled BOC-glycine fragment is split off the pentagastrin in the small intestine -- it is absorbed through the intestinal wall, and -- enters first the portal and then the systemic circulation.
D000818:Animals; D001646:Bile; D002250:Carbon Radioisotopes; D005998:Glycine / Q000031:analogs & derivatives / Q000378:metabolism; D007408:Intestinal Absorption; D008099:Liver / Q000378:metabolism; D008297:Male; D010418:Pentagastrin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism; D051381:Rats
D002250:Carbon Radioisotopes; C029052:BOC-glycine; C029051:rat gastrin C-terminal pentagastrin; D010418:Pentagastrin; D005998:Glycine