Effects of stimulation on the multiquantal spontaneous synaptic potentials in guinea pig hypogastric ganglia.
Loss frequency (0.5-2 Hz) stimulation of the preganglionic nerve produced calcium ion (Ca2+)-dependent increases in the frequency of spontaneous synaptic potentials recorded from guinea-pig hypogastric ganglion cells. The increased frequency was accompanied by a marked increase in the proportion of multiquantal spontaneous potentials and this was also dependent on extracellular Ca2+. The latter effect was interpreted as an increase in the degree of bursting within the spontaneous release process, supporting the hypothesis that the bursting is related to the cytoplasmic Ca2+ concentration.
D000818:Animals; D002118:Calcium / Q000494:pharmacology; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D005724:Ganglia / Q000187:drug effects / Q000502:physiology*; D006168:Guinea Pigs; D007001:Hypogastric Plexus / Q000187:drug effects / Q000502:physiology*
D002118:Calcium