title: Absorption of 35S-thiamine in jejunum and its brain and liver content in chickens on different selenium level diets.
abstract: The effect of 0.3, 3 and 10 mg SeO2 added to chicken ration on in vitro absorption of 35S-thiamine and its content in brain and liver have been studied. Addition of SeO2 inhibits thiamine absorption in chicken jejunum. With an increase of SeO2 in the ration thiamine transport decreases. Higher doses of SeO2 (3 and 10 mg) inhibit intestine alkaline phosphatase activity. A dose of 10 mg lowers total thiamine content in brain and liver, whereas 3 mg retains it.
mesh_terms: D000821:Animal Feed; D000818:Animals; D001923:Brain Chemistry; D002645:Chickens / Q000378:metabolism*; D007408:Intestinal Absorption / Q000187:drug effects*; D007583:Jejunum / Q000378:metabolism*; D008099:Liver / Q000032:analysis; D008297:Male; D012643:Selenium / Q000494:pharmacology*; D013831:Thiamine / Q000032:analysis / Q000378:metabolism*
chemical_list: D012643:Selenium; D013831:Thiamine