The effects of increased penetration of betamethasone dipropionate in a propylene glycol base (Diprolene) for psoriasis.
The efficacy and safety of betamethasone dipropionate, 0.05% in a propylene glycol base (Diprolene), was investigated in an open, fixed-dose study of thirty-one patients with resistant psoriasis. Clearing of lesions or marked improvement occurred in 97% (thirty out of thirty-one) of patients. Increased penetration of corticosteroid did not cause adrenal suppression or other adverse reactions.
D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D011409:Propylene Glycols; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*
D011409:Propylene Glycols; D006854:Hydrocortisone