[Lipid peroxidation and retinal damage in stress].
It is shown that in rats exposed to emotional-pain stress, the electric activity of the retina is inhibited (the magnitude of electroretinogram waves is lowered). At the same time the products of lipid peroxidation accumulate and the content of the natural antioxidant alpha-tocopherol decreases in the retina. Preliminary administration to the animals of synthetic antioxidants (4-methyl-2,6-ditretbutylphenol, OP-6 belonging to the hydroxypyridine series) prevents the accumulation of lipid peroxidation products and protects the electric activity of the retina.
D000818:Animals; D004596:Electroretinography; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism*; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000378:metabolism*; D013315:Stress, Psychological / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D013997:Time Factors; D014810:Vitamin E / Q000378:metabolism
D008054:Lipid Peroxides; D014810:Vitamin E; D013482:Superoxide Dismutase
Perekisnoe okislenie lipidov i povrezhdenie setchatki pri stresse.