title: [Asparaginase and adenosine deaminase activities in rat liver under different conditions of protein and protein-free diet].
abstract: The activities of asparaginase and adenosine desaminase were determined in the liver tissue and that of adenosine desaminase--in blood serum of rats under different conditions of protein and protein-free diet. The asparaginase activity is shown to decrease significantly in the liver tissue under conditions of protein-free diet and increases under long complete protein and complete caloric diet as well as under complete fasting. The adenosine desaminase activity in the liver tissue lowers significantly as compared to the control under conditions of both the 20-day complete protein diet and protein diet and increases to some extent as compared to its level in the animals under conditions of protein deficiency and complete fasting. In blood serum the adenosine desaminase activity decreases under the 20-day complete protein diet and when transferring rats from the 10-day protein-free diet to the 10-day complete protein diet. It is supposed that the unidirectional change in the adenosine desaminase activity in the liver tissue under different conditions of feeding is associated with the diversity of ways stimulating the production of adenosine in the decomposition processes.
mesh_terms: D000243:Adenosine Deaminase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001215:Asparaginase / Q000378:metabolism*; D004044:Dietary Proteins / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D009700:Nucleoside Deaminases / Q000378:metabolism*; D011488:Protein Deficiency / Q000201:enzymology*; D051381:Rats
chemical_list: D004044:Dietary Proteins; D001215:Asparaginase; D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase
vernacular_title: Asparaginaznaia i adenozindezaminaznaia aktivnosti v tkani pecheni krys pri razlichnykh usloviiakh belkovogo i bezbelkovogo pitaniia.