title: The effect of vagotomy on the distribution of sulphomucin-containing cells in the rat pyloric antrum.
abstract: The present histological investigation showed that bilateral truncal vagotomy (with accompanying pyloroplasty) reduced the sulphomucin-containing cell population of the pyloric antral mucosa of the rat stomach. Although this did not reach statistical significance (95% confidence limits), study of the absolute distribution of the sulphomucin-containing cells showed that significantly fewer of these cells were situated in the basal third of the mucosa as a result of the operation. A study of the percentage distribution revealed that a much higher percentage of sulphomucin-containing cells was present in the middle third of the mucosa in vagotomized rats than in the corresponding regions of the control stomachs. Thus, vagotomy and pyloroplasty had effected a redistribution of the sulphomucin-containing cells in the pyloric antrum. The possible explanation and significance of this finding are discussed.
mesh_terms: D000818:Animals; D002452:Cell Count; D005753:Gastric Mucosa / Q000032:analysis / Q000166:cytology*; D006651:Histocytochemistry; D008297:Male; D009077:Mucins / Q000032:analysis; D011706:Pyloric Antrum / Q000032:analysis / Q000166:cytology*; D051381:Rats; D013270:Stomach / Q000033:anatomy & histology; D014628:Vagotomy
chemical_list: D009077:Mucins; C012564:sulfomucin