[The success and complications of antenatal corticosteroid treatment to improve pulmonary maturity: a question of the dosage? (author's transl)].
From January 1978 to December 1979 cortico-steroids to improve prenatal pulmonary maturity were administered to 174 patients. Patients with additional factors to accelerate pulmonary maturity or patients with additional factors to pre-dispose to pulmonary asphyxia during labor were not evaluated. 43 patients who delivered 47 children were studied. The cortico-steroid treatment and delay of delivery for over 48 hours improved the survival chances of the pre-mature infants. Following the administration of 4 times 2 mg beta-methasone-phosphate 26.7% of the infants had respiratory distress syndrome whereas no respiratory distress syndrome was found after 4 times 4 mg of beta-methasone-phosphate.
D001623:Betamethasone / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control*
D001623:Betamethasone
Erfolg und Komplikationen bei pränataler Lungenreifeförderung mit Kortikosteroiden; eine Fragea der Dosierung?