title: Dominant lethal mutations in Tilapia mossambica (Peters) elicited by myleran.
abstract: Tilapia mossambica (Peters) Teleostei, Cichlidae, is of commercial importance being farmed for human consumption. An effective means of sterilization would be of value since prolific breeding under farming conditions reduces growth rate. The possibility of using the antileukaemic drug myleran as a chemosterilant has been investigated previously, however the present study indicated that it can induce dominant lethal mutations in this species.
mesh_terms: D000818:Animals; D002066:Busulfan / Q000494:pharmacology*; D005260:Female; D005399:Fishes / Q000235:genetics*; D005799:Genes, Dominant; D005804:Genes, Lethal; D008297:Male; D009152:Mutagenicity Tests; D009154:Mutation
chemical_list: D002066:Busulfan