Synthesis of dermorphins, a new class of opiate-like peptides.
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (dermorphin) and H-Tyr-D-Ala-Phe-Gly-Tyr-Hyp-Ser-NH2 (Hyp6-dermorphin) are two members of a new class of opiate-like peptides present in the amphibian skin. Their syntheses and that of the L-Ala2-analogue of dermorphin have been accomplished by conventional segment condensation in solution.
D000595:Amino Acid Sequence; D000818:Animals; D001001:Anura; D008722:Methods; D009294:Narcotics / Q000032:analysis / Q000138:chemical synthesis*; D009842:Oligopeptides / Q000032:analysis / Q000138:chemical synthesis*; D018847:Opioid Peptides; D010446:Peptide Fragments
D009294:Narcotics; D009842:Oligopeptides; D018847:Opioid Peptides; D010446:Peptide Fragments; C030058:dermorphin; C030059:dermorphin, 4-Hyp(6)-