title: [Studies into specificity for dye test (DT), complement fixation (CF), and intradermal test (ST) in diagnosis of toxoplasmosis (author's transl)].
abstract: Reference is made to an earlier study into the usefulness of the intradermal test. Now, an account is given of the specificities of tests used at present for the detection of toxoplasmosis, with reference being made to 4,341 intradermal tests, 1,332 dye tests, and 880 complement fixations. -- The three methods are qualitatively and quantitatively compared in great detail, with the close correlations between them explained. Reference is also made to the different origins of the antibody types detectable by the methods concerned. -- It seems to be quite obvious that the production of those antibody types differs in time and site, just as their lives are different in length. These findings actually are used as a point of departure for more detailed methodical proposals that should be followed in the search for an acute infection with Toxoplasma gondii. -- Various effects which might lead to unspecific tests are described in some length. -- All the above studies and findings have been used to compile a diagnosis diagram which may be a good basis for clinical decision-making on therapy.
mesh_terms: D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D008751:Methylene Blue; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D012882:Skin Tests; D014123:Toxoplasmosis / Q000175:diagnosis*
chemical_list: D008751:Methylene Blue
vernacular_title: Untersuchungen zur Spezifität des Serofarbtests (SFT), der Komplementbindungsreaktion (KBR) und des Instradermaltests (IDT) in der Toxoplasmosediagnostik.