[Absence of effect of ethanol and apple brandy on the upper digestive tract and esophagus of the Wistar rat. Part of a research project to assess etiological factors of cancer of the esophagus in the west of France (author's transl)].
Epidemiological studies have shown the role of alcohol in esophageal cancer in the West of France. Experiments were undertaken on Wistar rats to study the effect of locally consumed alcoholic beverages on the esophagus. Neither histological modifications, precancerous lesions nor cancer were observed in the animals. There was no significant excess of benign or malignant tumours in treated animals when compared with controls.
D000434:Alcoholic Beverages; D000818:Animals; D004064:Digestive System / Q000187:drug effects; D004938:Esophageal Neoplasms / Q000453:epidemiology / Q000209:etiology*; D004947:Esophagus / Q000033:anatomy & histology / Q000187:drug effects*; D000431:Ethanol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005602:France; D005638:Fruit; D006801:Humans; D008297:Male; D051381:Rats
D000431:Ethanol
Absence d'effet de l'éthanol et des eaux de vie de cidre sur le tractus digestif supérieur et l'oesophage du rat Wistar. Suite des recherches concernant les facteurs étiologiques du cancer de l'oesophage dans l'ouest de la France.