[The diagnosis of the Pendred syndrome in children by the perchlorate discharge test with 123I (author's transl)].
A modified method for the diagnosis of the Pendred Syndrome in children by the Perchlorate discharge test using 123I is described. The older child, who has the Pendred Syndrome and the obligatory hearing deficit, frequently has neither a goitre nor hypothyroidism, but other investigations (bone growth, scars and function tests) can also show changes. However a more certain diagnosis of this disorder in children is possible by the Perchlorate discharge test using 123I. The test using 131I is no longer justified in the face of more recent radiobiological knowledge.
D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006042:Goiter / Q000000981:diagnostic imaging* / Q000235:genetics; D034381:Hearing Loss / Q000000981:diagnostic imaging*; D006314:Hearing Loss, Conductive / Q000000981:diagnostic imaging* / Q000235:genetics; D006801:Humans; D007037:Hypothyroidism / Q000000981:diagnostic imaging* / Q000235:genetics; D007457:Iodine Radioisotopes; D008297:Male; D011877:Radionuclide Imaging
D007457:Iodine Radioisotopes
Die Diagnose des Pendred-Syndroms bei Kindern mit Hilfe des Depletions-Testes mit 123Jod.