Case study: complications associated with anticoagulant therapy.
A 42 year old male with gram negative pneumonia complicated by deep venous thrombosis was followed throughout his hospital stay and for two weeks following discharge. The treatment course is divided into five treatment periods, each with accompanying commentary. Drug interactions and neutralizations as well as dietary factors contributed to a complicated course. Laboratory determinations were used to directly evaluate therapeutic anticoagulant effects, and dosage regimens were adjusted to achieve desired anticoagulant levels.
D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects; D004347:Drug Interactions; D006470:Hemorrhage / Q000139:chemically induced; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008297:Male; D013924:Thrombophlebitis / Q000188:drug therapy*; D014859:Warfarin / Q000008:administration & dosage / Q000009:adverse effects
D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin; D001241:Aspirin