title: The diuretic phase of respiratory distress syndrome and its relationship to oxygenation.
abstract: To determine the relationship between improvement in pulmonary function and diuresis in respiratory distress syndrome, ten consecutive premature infants requiring mechanical ventilation for severe RDS were studied. Every infant had a diuresis (output/intake greater than 80%), which began at 26 to 34 hours of life and which lasted for an additional 64-72 hours. The diuresis preceded significant improvement in AaDo2 and ventilator settings (IMV, PIP, PEEP) by 52 hours. There was a significant decrease in body weight among all study infants during the first four days of life despite an increase in fluid intake. This study suggests a relationship in RDS between improvement in oxygenation and removal of interstitial lung edema.
mesh_terms: D001835:Body Weight; D004231:Diuresis; D006801:Humans; D007231:Infant, Newborn; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000503:physiopathology* / Q000628:therapy; D013997:Time Factors