[Nosology of contraceptives: hematological and ultrastructural observations after experimental administration of low dosage contraceptives (author's transl)].
A further experimental study on changes produced in rabbits by low dosage contraceptives is presented. The administration has been continued for six months. Serum biochemical and hepatic ultrastructural findings are in agreements with literature data. On the contrary the early changes of cardiac microcirculation and chiefly renal glomerular tuft seem to be rather unusual. The weight to be attached to the knowledges descending from the presented data in assessing allowance of contraceptive treatments in human subjects and aiming preventive medicine purposes is emphasized.
D000818:Animals; D001663:Bilirubin / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003276:Contraceptives, Oral / Q000494:pharmacology*; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000494:pharmacology*; D003326:Coronary Circulation / Q000187:drug effects; D003404:Creatinine / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006321:Heart / Q000187:drug effects; D007668:Kidney / Q000187:drug effects / Q000648:ultrastructure*; D008099:Liver / Q000187:drug effects / Q000648:ultrastructure*; D009206:Myocardium / Q000648:ultrastructure*; D011817:Rabbits
D003276:Contraceptives, Oral; D003277:Contraceptives, Oral, Combined; D005340:Fibrinogen; D002784:Cholesterol; D003404:Creatinine; D001663:Bilirubin
Nosografismo iatrogeno da contraccettivi: rilievi ematochimici ed ultrastrutturali dopo somministrazione sperimentale di estroprogestinici a basso dosaggio.