[New data on the participation of beta-endorphin in the neuroendocrine control of luteinizing hormone release].
In the experiments on rats the influence of the endogenic opioid beta-endorphine on the blood and hypophysis luteinizing hormone levels was studied after microiontophoretic injection of the hormone into diencephalon preoptic region. beta-Endorphine was shown to induce a significant decrease in blood hormone level and its increase in the hypophysis. No correlation was found between the changed hormone levels in the blood and hypophysis and beta-endorphine action. It is suggested that beta-endorphine participates in the mechanism, controlling luteinizing hormone release at the level of the cyclic center that regulates hypophyseal gonadotropic function.
D000818:Animals; D004723:Endorphins / Q000494:pharmacology / Q000502:physiology*; D005260:Female; D007986:Luteinizing Hormone / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects; D010902:Pituitary Gland / Q000378:metabolism; D011247:Pregnancy; D011301:Preoptic Area / Q000187:drug effects; D011359:Proestrus / Q000187:drug effects; D051381:Rats
D004723:Endorphins; D007986:Luteinizing Hormone
Novye dannye ob uchastii beta-éndorfina v neĭroéndokrinnom kontrole osvobozhdeniia liuteiniziruiushchego gormona.