Bilateral symmetrical brain lesions in tricyclic antidepressant overdosage.
The cerebral pathology in a case of tricyclic antidepressant overdose by amitriptyline is described. A review of the literature of similar cases is summarized. The relation of the cerebral lesions to the development of a hypertensive episode possibly induced by amitriptyline is discussed.
D000328:Adult; D000639:Amitriptyline / Q000506:poisoning*; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000139:chemically induced*; D002543:Cerebral Hemorrhage / Q000139:chemically induced; D003342:Corpus Striatum / Q000473:pathology; D005260:Female; D005917:Globus Pallidus / Q000473:pathology; D006801:Humans; D009336:Necrosis
D000639:Amitriptyline