Plasmapheresis decreases neuroelectric blocking activity in multiple sclerosis.
Serum neuroelectric blocking factor activity diminished after plasmapheresis in five of seven patients with MS but returned to baseline levels in 2 to 3 weeks. In the other two patients changes were insignificant. All patients studied had progressing symptoms. Five plasma exchanges of 2 liters were performed in 10 days. Two patients improved clinically, whereas five did not. There was no correlation between the level of neuroelectric blocking activity and changes in clinical status.
D000328:Adult; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D010956:Plasmapheresis; D013126:Spinal Nerve Roots / Q000503:physiopathology; D013997:Time Factors; D014792:Visual Acuity