[Hyperinsulinism probably caused by diffuse pancreatic hyperplasia].
A case history of a two years seven months old boy with hyperinsulinism and marked psychomotor retardation is presented. In this patient, biochemical analysis revealed persistent hypoglycemia. Basal insulin levels (RIA) were consistently superior to 10 mU/ml. and were higher than would be expected from the child's glycemias. Angiographic study of the celiac trunk revealed diffuse pancreatic enlargement. Therapy was initiated with oral diazoxide normalizing and stabilizing the patient's glycemia. The importance of an early diagnosis of this condition and the necessary biochemical analyses involved are discussed as well as the use of diazoxide in the medical treatment of hypoglycemia.
D002675:Child, Preschool; D003981:Diazoxide / Q000627:therapeutic use; D006801:Humans; D006946:Hyperinsulinism / Q000188:drug therapy / Q000209:etiology*; D006965:Hyperplasia; D007003:Hypoglycemia / Q000209:etiology; D008297:Male; D010179:Pancreas / Q000473:pathology*; D011596:Psychomotor Disorders / Q000209:etiology
D003981:Diazoxide
Hiperinsulinismo por probable hiperplasia difusa pancreática.