Relationships between the extent of ileal lesion of resection and vitamin B12, bile salt and fat absorption.
Vitamin B12 Urinary excretion, stool weight, fecal fat excretion, fecal 14C glycocholate excretion and 14CO2 output after I-14C glycocholate ingestion, were measured in 13 patients with non-operated ileal Crohn's disease (NOC), 14 patients with ileal resection for ileal Crohn's disease, with or without right colectomy (RC), and 11 patients with ileal resection with or without right colectomy for pathology other than Crohn's disease (RNC). A positive linear relationship was found between stool weight and 14C glycocholate fecal excretion. The logs of fecal fat and 14C glycocholate excretions were related to the extent of the ileal lesion of resection; a similar but negative relationship was observed for vitamin B12 urinary excretion. Fecal fat excretion and respiratory 14CO2 output were significantly higher in patients with right colectomy.
D001944:Breath Tests; D003082:Colectomy; D003424:Crohn Disease / Q000378:metabolism / Q000601:surgery; D005223:Fats / Q000032:analysis; D005243:Feces / Q000032:analysis*; D006000:Glycocholic Acid / Q000032:analysis; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007408:Intestinal Absorption; D014805:Vitamin B 12 / Q000652:urine*
D005223:Fats; D006000:Glycocholic Acid; D014805:Vitamin B 12