The fate of germ cells in the testis of fetal Sex-reversed mice.
XX germ cells in the fetal testes of XX Sex-reverse male mice were observed mostly to develop in the same manner as do XY germ cells in a normal fetal testis; but some, in the vicinity of the mesonephric rete region, entered the prophase of meiosis at the same time as do XX germ cells in a normal fetal ovary. No germ cells in meiosis were found in the fetal testes of XY males, nor of XO Sex-reversed males. It is suggested that a second X chromosome renders a germ cell more susceptible to the meiosis-inducing influence of the mesonephric rete.
D000818:Animals; D005260:Female; D005854:Germ Cells / Q000502:physiology*; D008297:Male; D008540:Meiosis; D051379:Mice; D008817:Mice, Mutant Strains / Q000196:embryology*; D010053:Ovary / Q000196:embryology; D011418:Prophase; D012729:Sex Chromosome Aberrations; D013737:Testis / Q000196:embryology*; D014960:X Chromosome