title: [Investigations of the etiology of bradycardial rhythm disturbances (author's transl)].
abstract: As a possible etiology of cardiac conduction disturbances the sclerosis of coronary arteries and an idiopathic fibrosis are considered. In recent time also a diabetes-typical process in the coronary artery system has been discussed. Therefore we studied the distribution of atherosclerotic risk factors in 238 patients with severe cardiac conduction disturbances. The results were: 1. The incidence of risk factors in patients with cardiac conduction disturbances is relatively high. 2. Nearly all risk factors were more frequent in patients with diabetes than in patients without this disease. 3. The average number of risk factors per patient is significantly higher in diabetic than in non diabetic patients. 4. The risk factors associated with diabetes mellitus--as hypertriglyceridaemia and hypercholesterolaemia--follow the same distribution function in diabetic patients and are therefore influenced by the diabetes in a similar fashion. Our results demonstrate that the atherosclerosis is the most probable cause of cardiac conduction disturbances. It seems unlikely that a diabetes-typical vessel disease is the primary cause of conduction disturbances in diabetic patients. Our results rather seem to demonstrate that the diabetes mellitus in general advance the process of atherosclerosis.
mesh_terms: D000328:Adult; D000368:Aged; D001919:Bradycardia / Q000209:etiology*; D003327:Coronary Disease / Q000150:complications; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006943:Hyperglycemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D012306:Risk
vernacular_title: Untersuchungen zur Atiologie bradykarder Herzrhythmusstörungen.