Computer simulation of the dynamics of cell populations.
A modified version of the program of Valleron and Friendel is presented for the computer simulation of growing populations of cells. The method effects a sizable reduction of the storage requirement and allows one to follow the growth and division of cell clones for a large number of generations. Moreover, it is particularly useful to simulate specific biological events assumed to occur in the cell under various hypotheses and to compare them. Examples of this are also given.
D000818:Animals; D002453:Cell Cycle; D002455:Cell Division; D002468:Cell Physiological Phenomena; D002477:Cells / Q000378:metabolism; D002999:Clone Cells; D003201:Computers; D004261:DNA Replication; D008954:Models, Biological