title: Kinetics of IgM and IgG responses in neonatally thymectomized Swiss mice under persistent immunization with sheep red blood cells.
abstract: The kinetics of IgM and IgG responses (direct and indirect PCF) in the Swiss mice, neonatally thymectomized, injected three times a week with 5 X 10(8) sheep erythrocytes at the age of two months, were exactly the same as the controls from the same litters. The thymectomized animals showed a statistically significant decrease in both responses (18.6 and 30.2%, respectively). The kinetics of the switch from IgM to IgG and of the latter response inhibition, is the same in both the control and the thymectomized animals.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000917:Antibody Formation; D004912:Erythrocytes / Q000276:immunology; D007114:Immunization; D007074:Immunoglobulin G / Q000276:immunology*; D007075:Immunoglobulin M / Q000276:immunology*; D051379:Mice / Q000276:immunology; D012756:Sheep / Q000276:immunology; D013934:Thymectomy
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M