title: Intravenous infusion of prostaglandin E2 for management of premature rupture of membranes.
abstract: In term with premature rupture of the membranes (PROM) and an unripe cervix who have no contraindications for prostaglandin (PG) administration and vaginal delivery, intravenous (I.V.) infusion of titrated PGE2 is highly effective. In healthy gravidas with dito fetus this treatment appeared perinatally safe and was well tolerated by the mother. To enhance its safety margin and procedure must be conducted under toco-cardiographic control.
mesh_terms: D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D011458:Prostaglandins E