Metabolism of limonene-1,2-epoxide in the rat.
1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, p-mentha-2,8-dien-1-alpha and -beta-ol and p-mentha-1,8-dien-6-alpha and -beta-ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.
D000818:Animals; D000081005:Cyclohexane Monoterpenes; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D039821:Monoterpenes; D051381:Rats; D013729:Terpenes / Q000378:metabolism*
D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes; D013729:Terpenes; C028940:limonene-1,2-epoxide