Serum level of alpha-N-acetyl-D-glucosaminidase in myocardial infarction in man.
alpha-N-acetyl-D-glucosaminidase, a lysosomal enzyme essential for the degradation of heparin sulfate, was measured in the sera of normal individuals and of 19 patients with myocardial infarction (MI). Normal individuals maintained a constant level of this enzyme from day to day. In contrast, patients with MI had a 2-3 fold elevation of this enzyme as early as 2 hr after MI. This elevation persisted at least until the creatine phosphokinase-MB had attained maximum activity, usually 6-23 hr after MI and then gradually decreased, returning to normal levels 3-5 days later.
D000118:Acetylglucosaminidase / Q000097:blood* / Q000378:metabolism; D000328:Adult; D044383:Black People; D006596:Hexosaminidases / Q000097:blood*; D006801:Humans; D009203:Myocardial Infarction / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology; D044465:White People
D006596:Hexosaminidases; D000118:Acetylglucosaminidase