Re-evaluation of the lymphocyte migration through the high-endothelial venules. Light and electron microscopic studies on the opossum's lymph node.
We have described two types of lymphocyte migration through the HEV. In the first case the lymphocytes do not show constriction ring during the diapedesis. 97% of lymphocytes migrate in this manner. In this migration pattern the lymphocyte gets through the endothelium by means of flexibility and pliability of the endothelium. It is suggested that these lymphocytes migrate into the blood from the lymph node. In the second case the lymphocytes undergo morphological changes, they form constriction ring and they migrate from the blood into the lymph node.
D000818:Animals; D002465:Cell Movement; D003238:Connective Tissue / Q000502:physiology / Q000648:ultrastructure; D004727:Endothelium / Q000502:physiology / Q000648:ultrastructure; D008198:Lymph Nodes / Q000502:physiology* / Q000648:ultrastructure; D008214:Lymphocytes / Q000502:physiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009893:Opossums