Hypocalcaemia increases the narcotic effect of codeine.
Severe narcosis occurred in a patient with hypoparathyroidism given therapeutic doses of codeine phosphate.
D001921:Brain / Q000187:drug effects; D003061:Codeine / Q000009:adverse effects*; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000150:complications*; D007011:Hypoparathyroidism / Q000150:complications; D008875:Middle Aged; D014474:Unconsciousness
D003061:Codeine