title: [Bromopride: metabolism and urinary elimination in dogs (author's transl)].
abstract: The elimination of bromopride and its metabolites was studied in dogs. The drug was given by mouth in a single dose of 15 mg/kg or 45 mg/kg and assessed by thin-layer or gas chromatography. Bromopride and its metabolites are excreted mainly within the first 8 h after ingestion. Nine metabolites, above all the N-monodeethyl derivative, were encountered, while 10% of the drug was eliminated as such.
mesh_terms: D000818:Animals; D001711:Biotransformation; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D004285:Dogs; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008787:Metoclopramide / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine
chemical_list: C013855:bromopride; D008787:Metoclopramide
vernacular_title: Bromoprid: metabolismus und renale Ausscheidung beim Hund.