A densitometric study of the effects of free fatty acids on the phase transition of dimyristoylphosphatidylcholine bilayers.
The technique of scanning densitometry was applied to a study of the effect of fatty acids on the packing and phase transition properties of dimyristolyphosphaticylcholine (DMPC). It was observed that the three fatty acids studied, i.e. palmitic, palmitoleic and behenic, had the effect of broadening the phase transition and increasing the extent of the change in volume which occurs at the phase transition. Palmitic and behenic acids broaden the phase transition toward higher temperatures while palmitoleic broadens it toward lower temperatures.
D003720:Densitometry; D004134:Dimyristoylphosphatidylcholine; D005230:Fatty Acids, Nonesterified; D008051:Lipid Bilayers; D008968:Molecular Conformation; D010713:Phosphatidylcholines; D013329:Structure-Activity Relationship
D005230:Fatty Acids, Nonesterified; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D004134:Dimyristoylphosphatidylcholine