title: Dietary, caging and temperature factors in the ageing of collagen fibres in rat tail tendon.
abstract: The effect of dietary fat, carbohydrate and protein on tail tendon collagen ageing was studied in male Wistar rats. When rats were fed low-calorie diets there was no evidence that the content of carbohydrate, fat or protein affected the ageing of collagen. However, on high-calorie diets there was evidence that high-fat diets (21%) either saturated or unsaturated aged collagen fibres at a faster than low-fat diets (7%). Isolated housing of rats, which is necessary to control food intake, was found to slow the rate of collagen ageing. This effect was associated with reduced tail tendon temperatures.
mesh_terms: D000375:Aging; D000818:Animals; D003094:Collagen / Q000378:metabolism*; D004032:Diet; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D051381:Rats; D012931:Social Environment; D013696:Temperature; D013710:Tendons / Q000378:metabolism*
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D003094:Collagen