title: [Creatininphosphokinase isoenzymes in anaesthesia-induced myoglobinuria (AIM) (author's transl)].
abstract: During a three year period, pediatric patients 4 to 16 years old were post-operatively screened for anaesthesia-induced myoglobinuria. All investigated cases had general anaesthesia and received succinylcholine prior to intubation. Anaesthetics were predominantly performed for tonsillectomies and/or adenoidectomies. Of a total of 1704 anaesthetics, 7 (0.4%) resulted in postoperative myoglobinuria without hyperthermia. Anaesthesia-induced myoglobinuria occurs more often than previously presented. This abnormal reaction to succinylcholine is not harmless in all cases. The possible genetic influence on total CPK and its isoenzymes is discussed.
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D009212:Myoglobinuria / Q000139:chemically induced* / Q000201:enzymology / Q000235:genetics; D010375:Pedigree; D013390:Succinylcholine / Q000009:adverse effects
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase; D013390:Succinylcholine
vernacular_title: CK Isoenzyme bei anaesthesie-induzierter Myoglobinurie (AIM).