title: [Mechanism of changing the cellular composition of the bone marrow during experimental toxic diphtheria].
abstract: Hemopoietic shifts in the bone marrow under experimental diphtheria intoxication have been studied. The number of immature elements of the erythroid series was shown to be lowered in the presence of an increase in the granulocyte pool. Under these conditions the erythroid sprout did not respond to bloodletting and the number of reticulocytes in the peripheral blood significantly dropped. However, there was an increase in the inclusion of 59Fe in red cells. The adrenomimetic ephedrine raised the content of reticulocytes in blood and 59Fe inclusion in red cells in the experimental animals and stimulated the reproduction of the erythroid series cells.
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology*; D002452:Cell Count; D004165:Diphtheria / Q000473:pathology* / Q000503:physiopathology; D004809:Ephedrine; D005260:Female; D006410:Hematopoiesis; D007501:Iron / Q000378:metabolism; D051381:Rats; D012156:Reticulocytes
chemical_list: D007501:Iron; D004809:Ephedrine
vernacular_title: K mekhanizmu izmeneniia kletochnogo sostava kostnogo mozga pri éksperimental'noĭ toksicheskoĭ difterii.