title: [Preparation and study of the antimycotic activity of 2-substituted 1,3-benzodithiols].
abstract: A series of 1,3-benzodithiols substituted at position 2, obtained by condensation of benzene 1,2-dithiols with aldehydes and ketones, was studied for antifungal activity. The fungistatic activity of the compounds [Table I, II; (I leads to XXV)] was tested in vitro against the four strains: Candida albicans, Candida tropicalis, Saccharomyces cerevisiae and Trichophyton mentagrophytes. The results indicate at the 2-monosubstituted 1,3-benzodithiols are an interesting class of antifungal substances, the 2-phenyl substituted derivative (1) being of particular interest.
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis*; D013876:Thiophenes / Q000138:chemical synthesis
chemical_list: D000935:Antifungal Agents; D013876:Thiophenes
vernacular_title: Preparazione e studio dell'attività antimicotica di 1,3-benzoditioli 2-sostituiti.