title: Dissolution of retained duct stones by perfusion with monooctanoin via a Teflon catheter introduced endoscopically.
abstract: Retained bile duct stones in patients who have undergone prior cholecystectomy are removed by operation or endoscopic sphincterotomy. We achieved dissolution of cholesterol duct stones by perfusion with monooctanoin, a commercially available mixture of medium chain glycerides. Sixteen patients were treated in whom endoscopic sphincterotomy was impossible or unsuccessful. In 12 patients, 16 stones were dissolved within 6 to 25 days (mean, 15.6 days). In all successfully treated patients elevated serum liver enzymes became normal during therapy.
mesh_terms: D000368:Aged; D002210:Caprylates; D002404:Catheterization / Q000379:methods*; D002758:Cholangiography; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005989:Glycerides / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002210:Caprylates; D005989:Glycerides; C025343:monooctanoin