title: Failure of naloxone to alter exercise-induced growth hormone and prolactin release in normal men.
abstract: Growth hormone and prolactin levels during standardized exercise tests were measured in ten normal male volunteers, with and without previous intravenous administration of 4 mg naloxone. No significant influence of naloxone on hormone release could be observed. The lack of effect indicates that an opioid pathway is not involved in exercise-induced growth hormone and prolactin release in humans, in contrast to that in rats.
mesh_terms: D000328:Adult; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D005082:Physical Exertion; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D012636:Secretory Rate / Q000187:drug effects
chemical_list: D009270:Naloxone; D011388:Prolactin; D013006:Growth Hormone