Effect of hydroxynitrobenzylation of tryptophan-177 on reactivity of active site cysteine-25 in papain.
D000081:Acetamides / Q000494:pharmacology; D000085:Acetates / Q000494:pharmacology; D000477:Alkylating Agents / Q000494:pharmacology; D001665:Binding Sites / Q000187:drug effects; D003545:Cysteine / Q000378:metabolism*; D005033:Ethylmaleimide / Q000494:pharmacology; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007700:Kinetics; D009596:Nitrophenols / Q000494:pharmacology*; D010206:Papain / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014364:Tryptophan / Q000378:metabolism*
D000081:Acetamides; D000085:Acetates; D000477:Alkylating Agents; D009596:Nitrophenols; C013874:chloroacetamide; C007008:2-chloromethyl-4-nitrophenyl(N-carbobenzoxy)glycinate; C006972:chloroacetic acid; D014364:Tryptophan; D010206:Papain; D003545:Cysteine; D005033:Ethylmaleimide; D005998:Glycine