Effect of cimetidine on basal and betazole-stimulated gastric acid secretion in peptic ulcer.
The effect of cimetidine, a histamine H2-receptor antagonist, on basal and beta-zole-stimulated gastric acid secretion was studied in 28 patients with peptic ulcer. The results demonstrate that cimetidine (300 mg IM), is a potent inhibitor of both basal and betazole-stimulated gastric acid secretion.
D000328:Adult; D001625:Betazole / Q000494:pharmacology*; D002927:Cimetidine / Q000494:pharmacology*; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism*; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000503:physiopathology*; D011720:Pyrazoles / Q000494:pharmacology*
D006146:Guanidines; D011720:Pyrazoles; D001625:Betazole; D002927:Cimetidine