[Proximo-distal gradient of the paramucosal pH in the digestive tract of normal rats and at different times after bilateral truncal vagotomy].
Membrane pH (mpH) of the stomach, duodenum, jejunum, caecum and rectum was measured in intact and vagotomized rats 1--220 days after operation. It was ascertained that in the digestive canal of control and experimental rats there is a proximodistal gradient of mpH that is marked by two local pH drops: gastroduodenal and ileocaecal. Vagotomy results in changes of the mpH-relief of the gastrointestinal tract. The most pronounced changes were detected in the early period (days 1 and 7) after operation. After 14 days there sets in a temporary and relative normalization of the mpH gradient of the digestive canal. In the later periods (60--220 days) after vagotomy the changes in mpH could be seen only in the stomach.
D000818:Animals; D004064:Digestive System / Q000294:innervation / Q000378:metabolism; D013505:Digestive System Surgical Procedures; D006863:Hydrogen-Ion Concentration; D008297:Male; D051381:Rats; D013997:Time Factors; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology
Proksimo-distal'nyĭ gradient pristenochnogo pH v pishchevaritel'nom kanale krys v norme i v razlichnye sroki posle dvustoronneĭ stvolovoĭ vagotomii.