[Effect of ampicillin and oxacillin on fetal and neonatal development].
Ampicillin administration during pregnancy exerted no toxic effect on the developing fetus. However, it decreased the body weight of the progeny and the weight of the placenta. Oxacillin had an adverse effect on the pregnancy, labor, fetus and newborn. It is inferred that ampicillin can be used for treatment purposes at any time of the pregnancy whilst oxacillin administration might involve a high risk for the mother, fetus and newborn.
D000667:Ampicillin / Q000633:toxicity*; D000818:Animals; D001724:Birth Weight; D005260:Female; D005313:Fetal Death / Q000139:chemically induced*; D005315:Fetal Diseases / Q000139:chemically induced*; D005317:Fetal Growth Retardation / Q000139:chemically induced; D008431:Maternal-Fetal Exchange; D007744:Obstetric Labor Complications / Q000139:chemically induced*; D009929:Organ Size; D010068:Oxacillin / Q000633:toxicity*; D010922:Placenta Diseases / Q000139:chemically induced; D011247:Pregnancy; D051381:Rats
D000667:Ampicillin; D010068:Oxacillin
Vliianie ampitsillina i oksatsillina na razvitie ploda i novorozhdennogo v éksperimente.