The estimation of phenotype distributions from pedigree data.
A method is described to estimate from pedigree data that probability density function of a quantitative phenotype, given a specific genotype. Theoretically, pedigrees of any size or complexity that are segregating for conditions of known Mendelian inheritance can be used. Under certain circumstances, the estimates are unbiased by the method of ascertainment.
D005817:Genetic Counseling; D006801:Humans; D008433:Mathematics; D008957:Models, Genetic; D010375:Pedigree; D010641:Phenotype; D011336:Probability