Histological examination of the effect of differently fractionated irradiations in rat and mouse organs. I. Observations after 60Co-gamma whole-body irradiation.
After 60Co-gamma whole-body irradiation with a total dose of 4 Gy, fractionated in different manners, radiation injury is less after five fractions given daily than after two fractions given in 3-day intervals. This can histologically be shown on radiosensitive organs of rats and mice in some significant minority of the cases. After daily three, altogether 15 radiation fractions, only rarely can be observed further tissue sparing effect.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology / Q000528:radiation effects*; D003037:Cobalt Radioisotopes; D008198:Lymph Nodes / Q000473:pathology / Q000528:radiation effects*; D008297:Male; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D051381:Rats; D013154:Spleen / Q000473:pathology / Q000528:radiation effects*; D013950:Thymus Gland / Q000473:pathology / Q000528:radiation effects*
D003037:Cobalt Radioisotopes