Secretion of gastric acid and serum gastrin following antral exclusion in man.
Serum gastrins and secretion of gastric acid were determined in one patient with recurrent ulcer following a Billroth II gastrectomy with incomplete excision of gastric antrum. Antral exclusion resulted in a modest rise in serum gastrin from 86 pg/ml to 141 pg/ml. This rise in gastrin seemed responsible for an augmented Basal production of acid and the ulcer diathesis as excision of the antral remnant 18 months later resulted in normogastrinaemia, normal gastric acid secretion and disappearance of the ulcer diathesis.
D000328:Adult; D005743:Gastrectomy / Q000379:methods; D005744:Gastric Acid / Q000378:metabolism*; D005755:Gastrins / Q000097:blood*; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000503:physiopathology / Q000601:surgery*; D011706:Pyloric Antrum / Q000503:physiopathology / Q000601:surgery*; D012008:Recurrence; D012636:Secretory Rate
D005755:Gastrins