Effect of the type of diet on the distribution of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in rat small intestine.
The jejunoileal gradient for the HMG-CoA reductase activity in the microsomal fraction of the epithelial cells of the small intestine of rats given commercial pellets was reserved within a few days after changing the ration to a semipurified diet. The response of the reductase was essentially the same in villus and crypt cells.
D000818:Animals; D004032:Diet; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism*; D007082:Ileum / Q000201:enzymology; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D007583:Jejunum / Q000201:enzymology; D008861:Microsomes / Q000201:enzymology; D051381:Rats; D013997:Time Factors
D006903:Hydroxymethylglutaryl CoA Reductases