Liver biopsy diagnosis of unsuspected or unconfirmed lymphoproliferative or myeloproliferative disorders.
Review of 2,400 consecutive percutaneous liver biopsy specimens revealed 3 (0.1%) with morphologically unequivocal but clinically unsuspected or unconfirmed malignant lymphomas and 20 (0.8%) with infiltrates suggestive of or compatible with lymphoproliferative or myeloproliferative disorders. These diagnoses were subsequently confirmed in 7 of the 20 cases, whereas in 4 the nature of the infiltrates and the outcome remain undecided. In the remaining 9 cases, inflammatory sinusoidal infiltrates had been erroneously suspected to represent lymphoproliferative or myeloproliferative disorders.
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006505:Hepatitis / Q000175:diagnosis; D006801:Humans; D008099:Liver / Q000473:pathology*; D008223:Lymphoma / Q000175:diagnosis; D008232:Lymphoproliferative Disorders / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000175:diagnosis*