Wegener's granulomatosis and relapsing polychondritis: a case report.
Relapsing polychondritis, a rare disorder characterized by inflammation of cartilaginous tissue, is often associated with vasculitic features. Wegener's granulomatosis is an uncommon form of vasculitis, usually responsive to treatment with cyclophosphamide. A 59-yr-old man with relapsing polychondritis, initially well controlled by corticosteroid therapy, developed pulmonary infiltrates and glomerulonephritis. After pathological confirmation of Wegener's granulomatosis, cyclophosphamide therapy was instituted and remission achieved.
D003520:Cyclophosphamide / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000188:drug therapy
D003520:Cyclophosphamide