title: Lymphatic absorption of nonvolatile oxidation products of heated oils in the rat.
abstract: The lymphatic absorption of nonvolatile oxidation products (NVOP) formed during heating of fats was studied. Heated colza or soybean oils or synthetic triglycerides containing a definite aromatic or alicyclic fatty acid were fed to thoracic duct-cannulated rats. Tritium-labeled triolein was added to each dietary fat, as an internal standard, in order to calculate the percentage of lymphatic absorption of the ingested NVOP. Results show that 4% of the total polymeric acids, 53% of the total oxidized monomeric acids and 96% of the total cyclic monomeric acids were recovered in the lymphatic lipids. Gas liquid and quantitative thin layer chromatography of these 3 classes indicated that, within a NVOP class, the various constituents did not present the same absorption rate. The lymphatic absorptions of individual oxidized monomers were between 25 and 93%. Concerning the polymer fraction, the lymphatic recoveries were 1% (nonpolar dimers), 6.8% (polar dimers) and 12% (polar oligomers). Aromatic acids were absorbed to a lesser degree (50-60%) than cyclohexenic acids (91-98%).
mesh_terms: D000818:Animals; D053138:Cyclohexenes; D004041:Dietary Fats / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D006358:Hot Temperature; D007408:Intestinal Absorption; D007536:Isomerism; D008196:Lymph / Q000378:metabolism*; D008297:Male; D009821:Oils / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D013329:Structure-Activity Relationship; D014280:Triglycerides / Q000378:metabolism*; D014835:Volatilization
chemical_list: D053138:Cyclohexenes; D004041:Dietary Fats; D005227:Fatty Acids; D009821:Oils; D014280:Triglycerides; C029619:9-(2'-propylcyclohex-4'-en-1'-yl)nonanoic acid