title: [The influence of the thickness of the epidermis on transcutaneous PO2 (author's transl)].
abstract: It was the aim of the study to investigate the influence of the thickness of the epidermis determined by histological technique on transcutaneous pO2 measured with a commercial device (Transoxode, Hellige), The epidermis was found to be significantly thicker in human adults and guinea pigs as compared with babies and sheep fetuses. There is a good correlation between epidermal thickness and the transcutaneous-arterial pO2-difference. With increasing epidermal thickness (i.e. increasing diffusion distance) in transcutaneous pO2 decreases. Accordingly, the difference between arterial and transcutaneous pO2 is much smaller in babies and sheep fetuses as compared with adults and guinea pigs under physiological conditions.
mesh_terms: D000328:Adult; D000818:Animals; D006168:Guinea Pigs; D006801:Humans; D007231:Infant, Newborn; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D012756:Sheep; D012867:Skin / Q000166:cytology / Q000378:metabolism*
chemical_list: D010100:Oxygen
vernacular_title: Der Einfluss der Epidermisdicke auf die transkutane PO2-Messung.