[Do fixed combinations of digoxin and nitrates have a therapeutic advantage?].
The results of this study with 102 patients, suffering from cardiac insufficiency and coronary heart disease are that a fixed combination of digoxin with nitrate-compositions is not convenient. In 45 cases the digoxin dose had to be altered, partly even several times, whilst only in 23 patients an alteration of the dosage of the nitrate compositions had to be done, independently from the digoxin dose.
D003327:Coronary Disease / Q000188:drug therapy; D004077:Digoxin / Q000097:blood / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D009566:Nitrates / Q000627:therapeutic use*
D009566:Nitrates; D004077:Digoxin
Bringen fixe Kombinationen von Digoxin und Nitraten einen therapeutischen Vorteil?