title: Depression hostility and anxiety in hyperprolactinemic amenorrhea.
abstract: In order to evaluate the relationship of psychological distress to hyperprolactinemia, 20 patients with secondary amenorrhea were evaluated by a semi-structured research interview and administered the Kellner Symptom Questionnaire. Group A (10 patients with amenorrhea and hyperprolactinemia) reported significantly more symptoms of depression, hostility and anxiety than group B (10 patients with amenorrhea and normal basal levels of plasma prolactin). Both groups were significantly more anxious, depressed and reported more somatic symptoms than a normal control group (n = 10). 6 of the 10 patients in group A reported decrease in libido, while this was found only in 1 of the 10 patients of group B. The findings suggest that the syndrome of depression, hostility and anxiety in a woman complaining of amenorrhea, especially if associated with decreased libido and galactorrhea, can be a manifestation of hyperprolactinemia.
mesh_terms: D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000523:psychology*; D001007:Anxiety; D003863:Depression; D005260:Female; D005687:Galactorrhea / Q000097:blood / Q000523:psychology; D006791:Hostility; D006801:Humans; D007989:Libido; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*; D013577:Syndrome
chemical_list: D011388:Prolactin