[In vitro variations of hepatic glycogenolysis after incubation of rat liver slices in the presence of polyamines].
If rat liver histological sections, cut by cryostat, incubated in presence of different putrescine concentrations (diluted in Hanks medium) and stained with P.A.S. show no real changes in glycogenolysis, others in a medium containing spermidine or better spermine, proportionally to the concentration in polyamine and duration of incubation, show an increase in the staining of the hepatic cytoplasms compared with the relative controls which are sections incubated in Hanks medium during the same time. So, in these conditions, putrescine doesn't seem to have an influence on glycogenolysis, but spermidine and spermine have a protective effect on hepatic glycogen.
D000818:Animals; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008112:Liver Glycogen / Q000378:metabolism*; D008115:Liver Regeneration / Q000187:drug effects; D008297:Male; D011073:Polyamines / Q000494:pharmacology*; D011700:Putrescine / Q000494:pharmacology; D051381:Rats; D013095:Spermidine / Q000494:pharmacology; D013096:Spermine / Q000494:pharmacology
D008112:Liver Glycogen; D011073:Polyamines; D013096:Spermine; D013095:Spermidine; D011700:Putrescine
Variations in vitro de la glycogènolyse hépatique après incubation de coupes de foie de rat en présence de polyamines.