title: Melanoma.
abstract: Melanoma most often occurs on the leg in women and on the head or neck in men. The appearance of the lesion should suggest the diagnosis, but pathologic examination and classification based on depth of skin penetration are essential for optimal therapy. Wide surgical excision should be followed by lymph node dissection, chemotherapy and/or immunotherapy depending on classification.
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D007866:Leg; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology