title: Reproduction study in rats or ginseng extract G115.
abstract: The effect of ginseng extract G115 on reproductive performance was studied in two generations of Sprague-Dawley rats. Animals of both sexes were fed wither control diet or diet supplemented with ginseng extract G115 at dose levels of 1 . 5, 5 or 15 mg/kg body weight/day. Parameters of reproduction and lactation in the treated groups were comparable to those of the controls for two generations of dams and pups. For F1 males and females, no treatment-related effects were seen in weekly body weights and food consumption, haematological and clinical chemical data, and ophthalmic, gross and histopathological examinations. The gross autopsies of F1 and F2 animals also revealed no significant treatment-related findings.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005260:Female; D008297:Male; D005894:Panax; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012098:Reproduction / Q000187:drug effects*
chemical_list: D010936:Plant Extracts