title: Aggression and open-field activity of lead-exposed mice.
abstract: Blood lead levels were increased 11 to 18 times in mice that ingested a 5 mg/ml solution of lead acetate for 2 or 4 weeks, with no effect on weight gain. Although the lead treatment produced neither mortality nor obvious abnormalities, it nevertheless inhibited the development of isolation-induced aggression which was characteristic on the basis of changes in motor activity.
mesh_terms: D000374:Aggression / Q000187:drug effects*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D006801:Humans; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000523:psychology*; D008297:Male; D051379:Mice; D012934:Social Isolation; D013997:Time Factors
chemical_list: D007854:Lead