title: Synthesis and properties of benzo [d,e]estra-1,3,5(10)-triene-3, 17 beta-diol 17-acetate.
abstract: A new pentacyclic analogue of estradiol, benzo[d,e]estradiol 17-acetate, has been prepared and investigated for its hormonal and antitumor activity. Unlike related testosterone derivatives, the new compound did not display any interesting property.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004958:Estradiol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D004958:Estradiol; C029226:benzo(d,e)estra-1,3,5(10)-triene-3,17 beta-diol 17-acetate