title: Protocol for delayed contrast enhancement in computed tomography of cerebral neoplasia.
abstract: One hundred cranial computed tomograms of adults with known or suspected intracranial neoplasm were analyzed retrospectively. Rapid high-dose intravenous contrast infusion (84.6 g l) was followed by immediate and 1 1/2-hour delayed scans. Delayed images afforded more information than the initial series in 67% of cases. 11.5% false-negative examinations (i.e., no tumor reported) would have resulted if studies were terminated after the immediate post-infusion scans. No patient experienced clinically detectable renal compromise.
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D003974:Diatrizoate Meglumine / Q000008:administration & dosage; D005188:False Negative Reactions; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement; D008297:Male; D013724:Teratoma / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003974:Diatrizoate Meglumine