title: Interactions between prolactin and ovarian secretions during mammary tumorigenesis in the mouse.
abstract: The plasma levels of ovarian steroids and the steroid binding capacity in the cytosol of mammary glands have been determined in the low-mammary-tumor C3H/f (XVII) mice. Implantation of a pituitary under the kidney leads to an increase of all these parameters as well as a high mammary tumor incidence. Simultaneous administration of the trans isomer of broparestrol (TBP) leads to a decrease of all the parameters.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000378:metabolism; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism*; D051379:Mice; D010053:Ovary / Q000378:metabolism*; D010902:Pituitary Gland / Q000187:drug effects / Q000637:transplantation; D011374:Progesterone / Q000378:metabolism; D011388:Prolactin / Q000502:physiology*; D011960:Receptors, Estrogen / Q000378:metabolism; D011965:Receptors, Glucocorticoid / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D013267:Stilbenes / Q000494:pharmacology; D014184:Transplantation, Homologous
chemical_list: D011960:Receptors, Estrogen; D011965:Receptors, Glucocorticoid; D011980:Receptors, Progesterone; D013267:Stilbenes; D011374:Progesterone; D004958:Estradiol; C004507:broparoestrol; D011388:Prolactin