The influence of hyperosmotic stress on the blood-retinal barrier effects on the electroretinogram.
Electroretinographic recordings were obtained from cat eyes before and after an intracarotid injection of a hypertonic NaCl-solution. It was found that after the injection the c-wave decreased in amplitude or disappeared, but reappeared within a period of four to six hours, suggesting that there is a reversible opening of the tight junctions following osmotic stress.
D000818:Animals; D001794:Blood Pressure; D002199:Capillary Permeability / Q000187:drug effects*; D002415:Cats; D004596:Electroretinography; D009997:Osmotic Pressure; D012161:Retinal Artery / Q000503:physiopathology*; D012462:Saline Solution, Hypertonic / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology*
D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride