title: [Changes in immune reactivity of the organism and content of monoaminodicarboxylic acid and their derivatives in brain and spleen].
abstract: It is established in experiments with mice that the contrary effects on the immune system caused different changes in the level of monoaminodicarboxylic acids and their derivatives in the brain and spleen structures. While immunostimulation was accompanied by an increase in monoaminocarboxylic acids, immunodepression, on the contrary, was characterized by a decrease in their contents up to the level, which is lower than the initial one. The main task of the investigation was to find out if this correlation is of causal character, which might be indicative of the significance of maintaining the definite level of monoaminodicarboxylic acids and their derivatives in the brain immunocompetent organs for normal functioning of the immune system.
mesh_terms: D000600:Amino Acids, Dicarboxylic / Q000032:analysis*; D000818:Animals; D001921:Brain / Q000276:immunology*; D001923:Brain Chemistry; D007121:Immunocompetence; D007165:Immunosuppression Therapy; D051379:Mice; D013154:Spleen / Q000032:analysis / Q000276:immunology*
chemical_list: D000600:Amino Acids, Dicarboxylic
vernacular_title: Izmenenie immunologicheskoĭ reaktivnosti organizma i soderzhanie monoaminodikarbonovykh kislot i ikh proizvodnykh v golovnom mozge i selezenke.