Malignant catarrhal fever virus infectivity in rabbit macrophages and monocytes.
Malignant catarrhal fever virus (MCFV) infectivity was demonstrated in macrophages/monocytes collected from MCFV-infected rabbits. Thus, in addition to lymphocytes, macrophages and monocytes are probably involved in the pathogenesis of MCFV and could account for the widespread dissemination of MCFV, the very high mortality rate and the immunosuppression observed in MCFV-infected animals.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002417:Cattle; D002448:Cell Adhesion; D005260:Female; D006564:Herpesviridae / Q000472:pathogenicity*; D008264:Macrophages / Q000382:microbiology* / Q000637:transplantation; D008297:Male; D008304:Malignant Catarrh / Q000382:microbiology* / Q000635:transmission; D009000:Monocytes / Q000382:microbiology* / Q000637:transplantation; D010996:Pleural Effusion / Q000166:cytology; D011817:Rabbits