title: A clinical evaluation of xenon enhancement for computed tomography.
abstract: Xenon increases the attenuation coefficients of tissues in which it dissolves and, therefore, enhances lipid-rich material. The authors evaluated xenon enhancement for computed tomography. Patients and normal subjects were given xenon in subanesthetic concentrations and were scanned in a large aperture CT scanner. Patients tolerated 30-50% inhaled xenon well. Cerebral tissues and lung were enhanced by this concentration of xenon. Xenon inhalation in subanesthetic concentrations will be a useful technique for characterizing abnormal lipid tissues and for estimating cerebral blood flow.
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging; D002545:Brain Ischemia / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D005069:Evaluation Studies as Topic; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging; D011856:Radiographic Image Enhancement; D012119:Respiration; D014057:Tomography, X-Ray Computed; D014978:Xenon / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D014978:Xenon