Early and later replication patterns of increased resolution in human lymphocyte chromosomes.
High resolution patterns of DNA replications in human lymphocyte chromosomes during early and late S-phases were studied by means of the BrdU-Hoechst-Giemsa technique. The late replicating bands were found to be identical with highly detailed G-bands. Between early replicating bands and R-bands subtile differences were observed. A possible correlation between a replication band seen on the chromosomal level and a replication cluster observed after fiber autoradiography is discussed.
D002875:Chromosomes / Q000378:metabolism / Q000648:ultrastructure*; D004261:DNA Replication; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure