Effect of flubendazole on Cysticercus cellulosae in pigs.
The effect of flubendazole on Cysticercus cellulosae was tested in 15 pigs. In doses o 8.3 mg/kg body weight or more daily for 10 days the drug was lethal to the cysticerci, causing both macroscopic and microscopic morphological alterations. An in vitro test showed 0% viability of cysticerci in most of the treated pigs, whereas in 90-100% of 11 control pigs they were viable.
D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D001921:Brain / Q000469:parasitology; D003551:Cysticercosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D003552:Cysticercus / Q000187:drug effects; D008463:Mebendazole / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use*; D009132:Muscles / Q000469:parasitology; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy* / Q000469:parasitology
D000969:Antinematodal Agents; D001562:Benzimidazoles; D008463:Mebendazole; C018945:flubendazole