title: Oxytocin, vasopressin, and estrogen-stimulated neurophysin: daily patterns of concentration in cerebrospinal fluid.
abstract: The concentrations of oxytocin, arginine vasopressin, and estrogen stimulated neurophysin in cerebrospinal fluid of monkeys showed a daily fluctuation with high concentrations occurring during the light period. The patterns of oxytocin and estrogen-stimulated neurophysin in the cerebrospinal fluid were not observed in the plasma nor were they altered after the administration of a dose of estradiol that increased concentrations of estrogen-stimulated neurophysin in plasma. The disassociation between these cerebrospinal fluid and plasma patterns and values suggests that the secretory activity of neurons that release estrogen-stimulated neurophysin and oxytocin into the cerebrospinal fluid is controlled by mechanisms different from those that control their release into the plasma.
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000097:blood / Q000134:cerebrospinal fluid*; D002940:Circadian Rhythm; D004958:Estradiol / Q000494:pharmacology; D008253:Macaca mulatta; D008297:Male; D009476:Neurons, Efferent / Q000378:metabolism; D009481:Neurophysins / Q000134:cerebrospinal fluid*; D010121:Oxytocin / Q000097:blood / Q000134:cerebrospinal fluid*
chemical_list: D009481:Neurophysins; D001127:Arginine Vasopressin; D004958:Estradiol; D010121:Oxytocin