title: [Recent nutrition biochemical findings on the importance of vitamion E and selenium in man and animal].
abstract: Recent knowledge concerning the importance of vitamin E and selenium for the health and functional capacity are demonstrated. A lack of vitamin E in man was up to now proved only in immaturely born children, in whom the application of a water-soluble vitamin E preparation is to be recommended. In adults in endangiitis obliterans a favourable influence by higher dosage of vitamin E was established. The need of vitamin E depends on the supply with selenium, with unsaturated fatty acids and with S-containing aminoacids. Selenium is necessary for the synthesis of glutathion peroxidase. The vitamin E is mainly effective in the degradation of fatty acid-peroxide compounds in the membranes, the glutathion peroxidase in the soluble proportions of the cells. By numerous works of animals experiments importance of the two essential nutrition factors for the preservation of structure and function in the molecular region was clarified. The vitamin E is, among others, important for the detoxication processes in the liver and for the immune defense.
mesh_terms: D000740:Anemia / Q000209:etiology; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D002462:Cell Membrane / Q000502:physiology; D005979:Glutathione Peroxidase / Q000096:biosynthesis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008099:Liver / Q000502:physiology; D051379:Mice; D011200:Poultry; D012643:Selenium / Q000378:metabolism / Q000502:physiology*; D014810:Vitamin E / Q000494:pharmacology / Q000502:physiology*; D014811:Vitamin E Deficiency / Q000150:complications
chemical_list: D014810:Vitamin E; D005979:Glutathione Peroxidase; D012643:Selenium
vernacular_title: Neuere ernährungsbiochemische Erkenntnisse zur Bedeutung des Vitamin E und des Selens bei Mensch und Tier.