title: [Thallium-201-myocardial imaging after high dose dipyridamole (author's transl)].
abstract: Biphasic thallium-201-myocardial imaging was performed in 100 patients undergoing coronary angiography. The images were obtained in several views after the administration of dipyridamole (0.50 mg/kg body weight) and 4 hours later. 24 patients had normal coronary arteries or insignificant stenoses, in 74 patients a 70-percent or greater stenosis of one or more coronary arteries was present. 55 transmural myocardial scars were diagnosed by left ventriculography in 53 patients. The described method showed a sensitivity of 93 percent and a specificity of 96 percent in the detection of patients with significant coronary artery stenoses. Irreversible perfusion defects were found in 91 percent of myocardial scars, in additional 7 percent the scintigraphic defects were reversible. In patients with multivessel disease and transmural infarctions, only one third of non-infarction-related stenoses were recognized. The number of angiographically stenotic coronary arteries could be determined scintigraphically only in a minority of the cases. The regional sensitivity in the assessment of LAD and right coronary artery stenoses was higher than for the left circumflex artery (75%, 80%, and 48% resp.), the specificity was equally high for all three vessels (96%, 99%, 100%).
mesh_terms: D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004176:Dipyridamole / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium
chemical_list: D011868:Radioisotopes; D004176:Dipyridamole; D013793:Thallium
vernacular_title: Thallium-201-Myokardszintigraphie nach hochdosierter Dipyridamolgabe.