title: The value of zinc protoporphyrin in equine lead poisoning: a case report.
abstract: A diagnosis of lead poisoning in a foal was established based on clinical signs and the presence of an elevation in the concentration of blood lead (40 microgram/dl). Additionally, ZPP was determined in whole blood and found to be significantly elevated compared to 10 normal horses not exposed to lead (634 vs 73 microgram/dl). An elevation in ZPP in man has been found to be a sensitive biochemical indicator of lead toxicity even before overt clinical signs are present. This report suggests that ZPP may be a useful screening test for evaluating biological toxicity due to lead in horses and possibly other species.
mesh_terms: D000818:Animals; D002417:Cattle; D006734:Horse Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D007855:Lead Poisoning / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D011166:Porphyrins / Q000097:blood*; D011524:Protoporphyrins / Q000097:blood*; D015032:Zinc / Q000097:blood*
chemical_list: D011166:Porphyrins; D011524:Protoporphyrins; D015032:Zinc