title: [Asplenia: a study of 21 subjects splenectomized during childhood for spleen injury (author's transl)].
abstract: Clinical and biological studies were carried out in 21 subjects one to twenty-three years after the injured spleen had been removed. Asplenia did not give rise to clinical symptoms, did not facilitate infections and had no effect on growth. Laboratory investigations revealed a decrease in IgM in 6 subjects and minor quantitative and qualitative platelet abnormalities. The absence of Jolly's bodies in 7 subjects was suggestive of spleen regeneration, which was confirmed by scintigraphy in 2 cases. The significance of these findings in discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D001791:Blood Platelet Disorders / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007075:Immunoglobulin M / Q000172:deficiency; D008297:Male; D011877:Radionuclide Imaging; D012141:Respiratory Tract Infections / Q000517:prevention & control; D013154:Spleen / Q000000981:diagnostic imaging / Q000276:immunology / Q000293:injuries*; D013156:Splenectomy / Q000009:adverse effects*
chemical_list: D007075:Immunoglobulin M
vernacular_title: L'asplénie. Etude de 21 sujets splénectomisés dans l'enfance pour traumatisme.