Changes of essential metal levels in lungs of rats acutely exposed to ozone.
Male Wistar rats were exposed to 2 ppm ozone (O3) for 4, 8, and 12 h. Wet and dry weights and water content of the lung increased with exposure time. The changes of six essential metal contents in the lung were simultaneously determined by inductively coupled plasma-atomic emission spectrometry. The contents of calcium (Ca) and sodium (Na) increased progressively. Copper (Cu) content showed a significant increase after exposure for 8 h. Iron (Fe) and magnesium (Mg) contents showed significant increases at 4 and 12 h, respectively. Zinc (Zn) showed no significant increases at any exposure times.
D000818:Animals; D002118:Calcium / Q000032:analysis; D003300:Copper / Q000032:analysis; D008168:Lung / Q000032:analysis / Q000187:drug effects*; D008297:Male; D008670:Metals / Q000032:analysis*; D010126:Ozone / Q000506:poisoning*; D011188:Potassium / Q000032:analysis; D011654:Pulmonary Edema / Q000139:chemically induced; D051381:Rats; D012964:Sodium / Q000032:analysis
D008670:Metals; D010126:Ozone; D003300:Copper; D012964:Sodium; D011188:Potassium; D002118:Calcium