[Age characteristics of glycolipid distribution in rat tissues depending on the functional state of the thyroid gland].
Distribution of the content of cerebrosides in the rat tissues is established to be nonuniform for the series brain greater than spleen greater than lungs greater than liver greater than kidneys greater than heart greater than muscles. In the new born animals only traces of cerebrosides and considerable amounts of gangliosides are found. In the process of the morphological and functional maturing all the tissues get enriched by cerebrosides (till 45 days) and gangliosides (by 15 days) with their content decrease in certain tissues in the process of ageing. Experimental hypothyrosis is accompanied by a fall of the total content and a decrease in the amount of hormonal iodine in the tissues, the decrease being more significant in young animals. The age dynamics of the glycolipid content inthe tissues is maintained, but their highest accumulation is delayed and does not reach the maximum characteristics of the intact animals.
D000818:Animals; D001921:Brain / Q000378:metabolism; D002554:Cerebrosides / Q000378:metabolism; D005732:Gangliosides / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism*; D007037:Hypothyroidism / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D013154:Spleen / Q000378:metabolism; D013961:Thyroid Gland / Q000254:growth & development / Q000502:physiology*; D014018:Tissue Distribution
D002554:Cerebrosides; D005732:Gangliosides; D006017:Glycolipids
Vozrastnye osobennosti raspredeleniia glikolipi v tkaniakh krys v zavisimosti ot funktsionalvnogo sostoianiia shchitovidnoi zhelezy.