title: Latent expression of group c allotypes in rabbits.
abstract: Rabbits deficient in both c7 and c21 allotypes were found in a certain colony of partially inbred rabbits and appeared to lack IgG with gamma light chain. In this colony, the gamma-chain level in the serum was low as an inherited character, and the mode of hereditary transmission of group c allotype expression was not apparent from available breeding data. These rabbits and other random-bred rabbits under conditions of suppressed T-cell functions produced group c allotypes which otherwise never appeared.
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006824:Hybridization, Genetic; D007126:Immunoglobulin Allotypes / Q000096:biosynthesis / Q000235:genetics*; D007074:Immunoglobulin G / Q000032:analysis; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007178:Inbreeding; D011817:Rabbits
chemical_list: D007126:Immunoglobulin Allotypes; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents