Reproductive performance of DES-exposed female progeny.
The reproductive performance of 106 patients exposed in utero to diethylstilbestrol by maternal ingestion is described. Fetal wastage is high, apparently because of spontaneous abortion during the first and second trimesters. Recommendations are made for preconception counseling of exposed progeny to increase fetal salvage.
D000022:Abortion, Spontaneous / Q000453:epidemiology; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D003376:Counseling; D004054:Diethylstilbestrol / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011261:Pregnancy Trimester, First; D011272:Pregnancy, Multiple
D004054:Diethylstilbestrol