On the intracardiac use of combined adrenaline, isoprenaline and noradrenaline in the resuscitation of the heart beat - A review of resuscitation, Part II.
A combination of three cardiokinetics - adrenaline, isoprenaline, and noradrenaline, ("AIN") - have been rather widely used in certain hospitals of the People's Republic of China since the beginning of the 1970s. "AIN" was initially used by intracardiac injection in an attempt to restart the asystolic heart when other therapies failed. Fifty-nine cases of restoration of the heart action with various therapies were analyzed. It was concluded that "AIN" could be recommended as first-aid drugs in the restoration of difficult cases with asystolic hearts, but not under any condition or in every case. In the patients with potential arrhythmias, such as may occur in myocardial infarction, "AIN" may induce refractory ventricular fibrillation.
D002648:Child; D002681:China; D004338:Drug Combinations; D004837:Epinephrine / Q000627:therapeutic use*; D006323:Heart Arrest / Q000188:drug therapy*; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000627:therapeutic use*; D012151:Resuscitation / Q000379:methods*; D014693:Ventricular Fibrillation / Q000139:chemically induced*
D004338:Drug Combinations; D007545:Isoproterenol; D009638:Norepinephrine; D004837:Epinephrine