Molecular cloning and characterization of cDNA sequences coding for rat relaxin.
Using a synthetic oligonucleotide primer, cloned DNA fragments, each containing the entire coding sequence of rat relaxin, have been isolated from a clone 'bank' of ovarian mRNA sequences. The nucleotide sequence of these clones demonstrates that relaxin is synthesized as a preprorelaxin molecule with an unexpectedly large connecting peptide of 105 amino acid residues.
D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular / Q000379:methods*; D005260:Female; D005796:Genes; D010053:Ovary / Q000378:metabolism; D011247:Pregnancy; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D012065:Relaxin / Q000096:biosynthesis / Q000235:genetics*
D012333:RNA, Messenger; D012065:Relaxin