Resistance of Haemonchus contortus to thiophanate.
The occurrence of a field strain of Haemonchus contortus which was resistant to thiophanate and susceptible to thiabendazole and levamisole is reported. The LD95 of thiophanate for the strain was found to be 156.1 mg/kg and its resistance factor was 6.7. In possessing specific thiophanate resistance it differed from previously reported thiophanate resistant strains of H contortus which have been benzimidazole resistant worms that have possessed cross resistance to thiophanate.
D000818:Animals; D002219:Carbamates / Q000494:pharmacology*; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D006188:Haemonchiasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects*; D007978:Levamisole / Q000627:therapeutic use; D008297:Male; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology; D013827:Thiabendazole / Q000627:therapeutic use; D013875:Thiophanate / Q000494:pharmacology* / Q000627:therapeutic use; D014251:Trichostrongyloidea / Q000187:drug effects*; D014252:Trichostrongyloidiasis / Q000662:veterinary*
D002219:Carbamates; D007978:Levamisole; D013875:Thiophanate; D013827:Thiabendazole