Microtubule function in leukocytes from umbilical cord blood.
Polymorphonuclear neutrophils and lymphocytes from umbilical cord blood had a normal distribution of concanavalin A receptors on their surfaces and do not show an abnormal sensitivity to the microtubule disrupting drug colchicine. These experiments suggest that leukocytes from úmbilical cord blood do not show any developmental deficiency of the microtubule system.
D000328:Adult; D003078:Colchicine / Q000494:pharmacology; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D007231:Infant, Newborn; D007962:Leukocytes / Q000648:ultrastructure*; D008214:Lymphocytes / Q000648:ultrastructure; D008870:Microtubules / Q000502:physiology*; D009504:Neutrophils / Q000648:ultrastructure; D011952:Receptors, Concanavalin A / Q000378:metabolism*
D011952:Receptors, Concanavalin A; D003078:Colchicine