title: Radical surgery in the management of clear cell adenocarcinoma of the cervix and vagina in young women.
abstract: The treatment of clear cell adenocarcinoma of the cervix and vagina in young women has varied widely from one institution to another. Since 1956, 16 such patients have been treated primarily with radical surgery at the University of California, San Francisco. The operations have ranged from radical hysterectomy and bilateral pelvic lymph node dissection with preservation of the ovaries to total pelvic exenteration, depending upon the location and extent of the disease. Vaginal reconstruction has been carried out in most of the patients who required vaginectomy. Eleven of the 16 patients are living and well. The remaining five have died of disease, two of them after relatively long disease-free intervals.
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008722:Methods; D011788:Quality of Life; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D014625:Vaginal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*