Kinetics of Craviten decomposition in aqueous solutions.
A method has been evolved for determination of Craviten and its degradation products making possible qualitative investigations on the hydrolysis process of this drug. Using this method studies were carried out on the stability of the aqueous solutions of Craviten in the pH range from 1.1 to 5.9, with calculation of the basic kinetic parameters. The aqueous solutions of Craviten have insufficient stability (t10% at 20 degrees C was 331 hrs).
D000889:Anti-Arrhythmia Agents; D002855:Chromatography, Thin Layer; D004355:Drug Stability; D005029:Ethylenediamines; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D012996:Solutions; D013053:Spectrophotometry; D013696:Temperature
D000889:Anti-Arrhythmia Agents; D005029:Ethylenediamines; D012996:Solutions; C030706:butobendin