[Prevention of myalgias caused by succinylcholine with a small dose of a non-depolarizing muscle relaxant].
Precurarisation with 1 mg/15 kg d-tubocurarine was given before 1.5 mg/kg succinylcholine to obtain muscle relaxation for tracheal intubation in 100 patients, whereas 1 mg/kg succinylcholine only was administered to 100 controls. Serious postoperative myalgia fell from 8% to 0%, and forms of average intensity from 21% to 8% in the curarised group. Muscle resolution was regarded as satisfactory in 96% (98% in the controls). The effectiveness and degree of safety of this combination are discussed, together with the indications and contraindications for the employment of the technique in the prevention of myalgia induced by succinylcholine.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009132:Muscles; D010146:Pain / Q000139:chemically induced* / Q000517:prevention & control; D011229:Preanesthetic Medication / Q000009:adverse effects; D013390:Succinylcholine / Q000009:adverse effects*
D009125:Muscle Relaxants, Central; D013390:Succinylcholine
La prevenzione delle mialgie da succinilcolina con una piccola dosse di miorilassante non depolarizzante.