[Duodenal absorption of calcium in rats treated with 25 OHD3, diphosphonates and synthetic anabolics].
In this study the authors developed new technics of study of duodenal absorption of calcium in rats: atomic absorption spectrophotometry, and dialysis to equilibrium. We considered that the main factors necessary for evaluation of duodenal absorption of calcium are the serum calcium, the calcium and alkaline phosphatase present in the duodenal cells and the calcium-binding proteins. The authors demonstrate that these factors are highest in rats treated with 25 OHD3 and norandrostenolone decanoate, than in control rats. In rats treated with diphosphonate, on the contrary, they obtained a reduction in the values of calcium and alkaline phosphatase contained in the duodenal cells.
D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D002112:Calcifediol; D002118:Calcium / Q000378:metabolism*; D004164:Diphosphonates / Q000494:pharmacology*; D004386:Duodenum / Q000378:metabolism*; D005260:Female; D006887:Hydroxycholecalciferols / Q000494:pharmacology*; D007408:Intestinal Absorption / Q000187:drug effects; D051381:Rats
D045930:Anabolic Agents; D004164:Diphosphonates; D006887:Hydroxycholecalciferols; D002112:Calcifediol; D002118:Calcium
Etude de l'absorption duodénale du calcium chez des rats traités avec 25 OHD3, avec diphosphonates et avec anabolisants de synthése.