title: [Preventing postoperative edema with Irritren. Results of a double-blind study].
abstract: In order to inhibit postoperative swelling we compared the new antiphlogistic Lonazolac-Ca with Diclofenac-Na in 20 patients each undergoing knee joint surgery. Leg volume increased in a smaller extent in the Lonazolac-Ca patients and pretreatment values were achieved on the 8th day. On the first day of physiotherapy (4th postoperative day) pain on motion was significantly less marked than before surgery in the Lonazolac-Ca group. No side-effects were observed in the Lonazolac-Ca group. One patient on Diclofenac-Na had to discontinue treatment on the 2nd day because of gastric disturbance and itching. Though both treatments showed good efficiency, Lonazolac-Ca was slightly superior.
mesh_terms: D000085:Acetates / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D004487:Edema / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011720:Pyrazoles / Q000627:therapeutic use*
chemical_list: D000085:Acetates; D011720:Pyrazoles; C017472:lonazolac
vernacular_title: Prophylaxe postoperativer Schwellungen mit Irritren. Ergebnisse einer Dopelblind-Studie.