In vitro induction of resistance to erythromycin by its metabolite.
Of the metabolites isolated from urine samples of patients treated with erythromycin, the 8,9-anhydroerythromycin A 6,9-hemiketal induced in vitro resistance to the parent drug and to carbomycin in the test strain Staphylococcus aureus RN 1389.
D003470:Culture Media; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D013211:Staphylococcus aureus / Q000187:drug effects*
D003470:Culture Media; D004917:Erythromycin