Experimental arterial aneurysms:modification of the production technique.
Vein pouches obtained from the external jugular vein were used to create experimental aneurysms on the carotid arteries of 13 rabbits and the abdominal aortas of 18 rabbits. Eighteen of these vein pouch aneurysms were grafted onto a linear incision in the artery; 13 of the aneurysms were grafted onto an elliptical incision. In 4 of the rabbits in which the vein pouch was grafted onto an elliptical arteriotomy in the carotid, a new approach for producing an intracranial aneurysm was attempted by relocating the aneurysm segment to the subarachnoid space at the cranial vertex. The results indicate that the aneurysms grafted onto an elliptical arteriotomy had a higher patency rate than the aneurysms grafted onto a linear arteriotomy in both the aortic and carotid models. Also, the attempt to produce an intracranial model demonstrated that short-term patency of the aneurysms could be achieved and that a two-stage approach to creating such aneurysms would be more appropriate than a one-stage approach.
D000783:Aneurysm / Q000000981:diagnostic imaging*; D000818:Animals; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging / Q000601:surgery; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging*; D002339:Carotid Arteries / Q000601:surgery; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging*; D004195:Disease Models, Animal; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D007601:Jugular Veins / Q000637:transplantation; D011817:Rabbits; D011859:Radiography; D013346:Subarachnoid Space; D014182:Transplantation, Autologous