[Tissue oxygen balance in relatives of diabetic patients and patients in the early stages of diabetes].
The results of clinical and instrumental examinations of microcirculation in diabetics with an early stage of the disease (25) and in the relatives of patients suffering from diabetes mellitus (89) are presented Capillaroscopy (capillaroscope MBC-1) was used for studying capillar circulation. The tissue oxygen balance was evaluated by means of polarography with functional tests. As a result, the capillar destruction and dysfunction were revealed in 2/3 of relatives and in all the patients with diabetes mellitus. The disorder of oxygen utilization and transport, indicating histotoxic and circulatory hypoxia presence, was found in the majority of subjects of both groups examined.
D000293:Adolescent; D000328:Adult; D001485:Basement Membrane / Q000378:metabolism; D002196:Capillaries / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000235:genetics / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000209:etiology; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D010101:Oxygen Consumption; D011236:Prediabetic State / Q000378:metabolism; D013997:Time Factors
Kislorodnyĭ balans tkaneĭ u rodstvennikov bol'nykh sakharnym diabetom i u bol'nykh s rannymi stadiiami diabeta.