title: Intraspinal tumors in children.
abstract: Thirty cases of intraspinal neoplasms occurring during the first two decades of life are reviewed. Histologic examination showed 13 of these to be astrocytomas, 6 neuroblastomas, 5 sarcomas, 3 ependymomas, 2 neurofibromas and 1 a schwannoma. Orthopedic deformities developed or worsened in 60 percent of patients surviving longer than a year after diagnosis. In five patients some form of endocrine deficiency developed after irradiation. For treatment of radiosensitive extradural malignant lesions, biopsy followed by irradiation is advocated.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001254:Astrocytoma / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D004806:Ependymoma / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009442:Neurilemmoma / Q000175:diagnosis; D009447:Neuroblastoma / Q000175:diagnosis; D009455:Neurofibroma / Q000175:diagnosis; D012509:Sarcoma / Q000175:diagnosis; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000453:epidemiology