[Determination of the probability of thrombocyte aggregation for evaluation of their functional state].
Basing on an analysis of the initial area of the aggregatogram a method has been suggested for determining the probability of platelet aggregation on collision. Calculation was performed in terms of a kinetic equation of coagulation according to the Smolukhovsky's approximation method and in terms of own experimental data. Good agreement of a theoretical depiction with experimental facts indicates the efficacy of the approach suggested to the appraisal of the probability of platelet aggregation, enabling the comparison of the results obtained with different plasma specimens. In contradistinction to a routine analysis of the aggregatograms (determination of the aggregation amplitude, and the time from the onset of the maximum aggregation), the probability of aggregation is determined only from platelet function.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D010974:Platelet Aggregation; D011817:Rabbits; D012701:Serotonin / Q000494:pharmacology
D012701:Serotonin; D000244:Adenosine Diphosphate
Opredelenie veroiatnosti agregatsii trombotsitov dlia otsenki ikh funktsional'nogo sostoianiia.