title: Renal scintigraphy: quantitative assessment of upper urinary tract dilatation in children.
abstract: A standard method of Tc-DTPA renal scintigraphy has been used to examine 426 dilated upper urinary tracts in children aged 2 days-16 yr. The method provides an accurate estimate of individual kidney function and defines the extent of dilatation. Renogram analysis and frusemide-induced diuresis have been applied in an attempt to distinguish between the obstructed upper tract and the dilated upper tract without obstruction. In 304 upper tracts, obstruction was predicted with an overall sensitivity of 0.87. The sensitivity for diagnosis of pelviureteric junction obstruction was 0.93. The value of scintigraphy in excluding significant obstruction and in follow-up studies is emphasized. This is a noninvasive, low-radiation investigation which plays an important role in the assessment of obstructive uropathy in childhood and represents a major advance in diagnostic facilities.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004231:Diuresis; D005665:Furosemide; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008722:Methods; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D014551:Urinary Tract / Q000000981:diagnostic imaging*
chemical_list: D004369:Pentetic Acid; D005665:Furosemide