Regional arm-brain mean transit time in the diagnostic evaluation of patients with cerebral vascular disease.
By analyzing time-activity curves over selected brain regions, following intravenous administration of non-diffusible radionuclide, it is possible to assess regional arm-brain mean transit time (rABmtT). By evaluating this parameter in normal subjects a relatively small range of differences between asymmetrical regions can be found (0.30 +/- 0.14 sec, mean +/- SD). An increase of this difference above statistical limits was found in 82% of patients with acute complete stroke, in 56% of patients with chronic complete stroke in 21% of patients with transient ischemic attacks.
D001132:Arm / Q000000981:diagnostic imaging*; D001921:Brain / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000503:physiopathology; D002543:Cerebral Hemorrhage / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D002546:Ischemic Attack, Transient / Q000503:physiopathology; D011877:Radionuclide Imaging; D012016:Reference Values; D013997:Time Factors