[Possibility of studying lipoperoxidation processes in surviving tissues].
A study was made of postmortem changes in the activity of "antioxidative" enzymes and in the content of primary and secondary products of lipid peroxidation in rabbit tissues (aorta, liver). It was found that the content of primary and secondary products of lipid peroxidation in the liver sharply rises already 1.5 h after the animals were sacrificed whereas no significant changes developed in the aorta over 9 hours. The activity of the "antioxidative" enzymes in the aorta or liver remains unchanged during these hours. Possibilities are discussed of studying the activity of superoxide dismutase and glutathion peroxidase, and the products of lipid peroxidation in cadaveric material obtained on rapid autopsy of suddenly deceased people.
D000818:Animals; D001011:Aorta / Q000201:enzymology / Q000378:metabolism*; D002682:Chinchilla; D007511:Ischemia / Q000201:enzymology; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008099:Liver / Q000098:blood supply / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010544:Peroxidases / Q000378:metabolism; D011180:Postmortem Changes; D011817:Rabbits; D013482:Superoxide Dismutase / Q000378:metabolism
D008054:Lipid Peroxides; D010544:Peroxidases; C027585:glutathione peroxidase II; D013482:Superoxide Dismutase
O vozmozhnosti issledovaniia protsessov lipoperoksidatsii v perezhivaiushchikh tkaniakh.