Stickler's syndrome.
During recent years a new syndrome involving degenerations of the corpus vitreum and retina, and dysplastic abnormities of the bones, Sticklers Syndrome, has been evaluated. The patients have a bad visual prognosis because of a tendency to often uncurable retinal detachment. Several patients have glaucoma simplex, but only few descriptions of the angles of the anterior chamber have been published. Two patients with typical malformations and abnormal angles of the anterior chamber are described. Gonoidysgenesis is assumed to be part of the syndrome, which seems to be more common than earlier assumed.
D000015:Abnormalities, Multiple / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000473:pathology; D002386:Cataract / Q000235:genetics*; D005128:Eye Diseases / Q000235:genetics; D005799:Genes, Dominant; D005901:Glaucoma / Q000235:genetics*; D006801:Humans; D008297:Male; D012162:Retinal Degeneration / Q000235:genetics*; D012163:Retinal Detachment / Q000235:genetics; D013577:Syndrome; D014822:Vitreous Body / Q000473:pathology*