Evaluation of the clinical electrophysiological effects of antianginal drugs without specific antiarrhythmic properties.
The authors have studied the electrophysiological effects of four antianginal drugs: oxyfedrine, nifedipine, dipyridamole and carbochromene. These drugs demonstrated different and sometimes contrasting effects on sinus node function, atrial refractoriness and atrioventricular conduction. These effects may constitute an indication or a contraindication in different clinical pictures and should be considered in the choice of treatment of patients with coronary artery disease.
D000787:Angina Pectoris / Q000188:drug therapy; D002317:Cardiovascular Agents / Q000494:pharmacology*; D002866:Chromonar / Q000494:pharmacology; D004176:Dipyridamole / Q000494:pharmacology; D004558:Electric Stimulation; D004569:Electroencephalography; D004594:Electrophysiology; D006321:Heart / Q000502:physiology; D006329:Heart Conduction System / Q000187:drug effects; D006801:Humans; D009543:Nifedipine / Q000494:pharmacology; D010099:Oxyfedrine / Q000494:pharmacology
D002317:Cardiovascular Agents; D004176:Dipyridamole; D010099:Oxyfedrine; D009543:Nifedipine; D002866:Chromonar