Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation.
By microbial transformation of tylosin (I), the following eight new acyl derivatives were obtained: 3-acetyltylosin (II), 3-propionyltylosin (III), 4"-butyryltylosin (IV), 4"-isovaleryltylosin (V), 3-acetyl-4"-butyryltylosin (VI), 3-acetyl-4"-isovaleryltylosin (VII), 3-propionyl-4"-butyryltylosin (VIII) and 3-propionyl-4"-isovaleryltylosin (IX).
D001711:Biotransformation; D055598:Chemical Phenomena; D002621:Chemistry; D002627:Chemistry, Physical; D007933:Leucomycins / Q000032:analysis / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013302:Streptomyces / Q000378:metabolism*
D007933:Leucomycins