[Cytogenetic studies for detection of tumour strain lines of ovarian cancer cells (author's transl)].
Reported in this paper are cytogenetic studies into cell cultures of tumour material, ascites, and pleural effusion obtained from 15 cases of histologically secured ovarian carcinoma. Identification of tumour cell strain lines was the purpose of those studies. Hypodiploid to hypertetraploid chromosome counts were established. Clearly pronounced peaks were recordable between 43 and 65 chromosomes, while smaller peaks were additionally established between 85 and 92 chromosomes. Numerical chromosome deviations were relating primarily to the C group. Marker chromosomes were established from six of 15 tumours. Different strain lines of tumour cells were recorded from twelve of 15 ovarian tumours. The number of cell strain lines was found to be in good agreement in 60 per cent of all findings, as compared with the oncobiograms.
D002460:Cell Line; D002877:Chromosomes, Human; D005260:Female; D006801:Humans; D007621:Karyotyping; D010051:Ovarian Neoplasms / Q000235:genetics*
Zytogenetische Untersuchungen zum Nachweis von Tumorzellstammlinien an Ovarialkarzinomzellen.