title: Changes in the activity of aspartate and alanine aminotransferase caused by aseptic inflammatory reaction and ionizing radiation in the liver, kidney and spleen of mice.
abstract: The activity of aspartate aminotransferase and alanine aminotransferase and the content of soluble proteins were determined in mice irradiated with single dose of 100 R or injected with turpentine and in mice subjected to both these stress factors. The aim of this study was determination of changes in the activity of both these enzymes in the liver, kidney and spleen within 48 hours). It was found that the action of both these stress factors caused significant changes in the activity of AspAT and A1AT in the first phase of the response of the organism to stress and caused statistically significant changes of this activity on the second day of the experiment.
mesh_terms: D000410:Alanine Transaminase / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology; D007249:Inflammation; D007668:Kidney / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D008297:Male; D051379:Mice; D009393:Nephritis / Q000139:chemically induced / Q000201:enzymology; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D013154:Spleen / Q000201:enzymology*; D013158:Splenic Diseases / Q000139:chemically induced / Q000201:enzymology; D014425:Turpentine
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D014425:Turpentine