The activity of plasma phosphatases in rats treated with single doses of dichlorvos and trichlorphon.
Intoxication of rats with single doses of Dichlorvos or Trichlorphon corresponding to 50% of the LD50 led to striking changes of blood plasma phosphatase activities. The complex pattern of these changes was not related to the observed inhibition of plasma cholinesterase. The tested pesticides did not inhibit plasma phosphatases in vitro.
D000135:Acid Phosphatase / Q000097:blood*; D000469:Alkaline Phosphatase / Q000097:blood*; D000818:Animals; D002802:Cholinesterases / Q000097:blood; D003864:Depression, Chemical; D004006:Dichlorvos / Q000008:administration & dosage* / Q000633:toxicity; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D013268:Stimulation, Chemical; D013997:Time Factors; D014236:Trichlorfon / Q000008:administration & dosage* / Q000633:toxicity
D004006:Dichlorvos; D014236:Trichlorfon; D002802:Cholinesterases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase