title: Insecticide levels in tissues associated with toxicity: a literature review.
abstract: Extensive residue studies have been done with most of the organochlorine insecticides. The brain is a reliable tissue to determine lethal or exposure residues of the persistent organochlorine insecticides. Fewer studies have been done with organophosphate residues. residues of organophosphate insecticides are useful indicators of poisoning in tissues of exposed animals. Metabolite determination and identification is a necessary consideration since metabolic activation is required for several of the organophosphate insecticides. No studies of tissue residue evaluation of carbamate insecticides are available.
mesh_terms: D000818:Animals; D001717:Birds; D001921:Brain / Q000378:metabolism; D002219:Carbamates; D002706:Chlordan / Q000378:metabolism; D003634:DDT / Q000378:metabolism; D004026:Dieldrin / Q000378:metabolism; D004732:Endrin / Q000378:metabolism; D005260:Female; D007306:Insecticides / Q000378:metabolism* / Q000633:toxicity*; D008297:Male; D009943:Organophosphorus Compounds; D051381:Rats; D014018:Tissue Distribution; D014112:Toxaphene / Q000378:metabolism
chemical_list: D002219:Carbamates; D007306:Insecticides; D009943:Organophosphorus Compounds; D002706:Chlordan; D014112:Toxaphene; D003634:DDT; D004026:Dieldrin; D004732:Endrin