title: [Inhibitory analysis of the luminescent electron transport chain of Photobacterium fischeri].
abstract: The quenching of luminescence of bacterial luciferase from Photobacterium fischeri by non-specific electron acceptors and inhibitors of dehydrogenases was studied. The inhibition of the luminescent reaction obeys the non-competitive mechanism with NADH, FMN and aliphatic aldehyde. The inhibitors compete with cytochrome c for NADH -- cytochrome c oxido-reductase. It is concluded that lumiredoxin, a FeS-containing protein, is the most sensitive component of the luminescent electron transport chain.
mesh_terms: D000447:Aldehydes / Q000494:pharmacology; D004579:Electron Transport / Q000187:drug effects; D005486:Flavin Mononucleotide / Q000494:pharmacology; D007700:Kinetics; D008156:Luciferases / Q000378:metabolism*; D008163:Luminescent Measurements; D009243:NAD / Q000494:pharmacology; D010084:Oxidation-Reduction; D010776:Photobacterium / Q000201:enzymology*
chemical_list: D000447:Aldehydes; D009243:NAD; D005486:Flavin Mononucleotide; D008156:Luciferases
vernacular_title: Ingibitornyĭ analiz liuminestsentnoí elektrontransportnoĭ tsepi Photobacterium fischeri.