Prostaglandin formation in bacteria : a reevaluation.
We report here that production and release of PGE2 do not occur in common bacteria. The apparent production in the presence of arachidonic acid, previously reported (1) may be explained by PGE2 contamination and autooxidation of the AA used. The presence of PGE2 like material in some but not all isolates of Propionibacterium acnes is confirmed.
D001095:Arachidonic Acids / Q000378:metabolism; D007213:Indomethacin / Q000494:pharmacology; D011425:Propionibacterium acnes / Q000187:drug effects / Q000378:metabolism*; D011458:Prostaglandins E / Q000378:metabolism*; D011863:Radioimmunoassay
D001095:Arachidonic Acids; D011458:Prostaglandins E; D007213:Indomethacin