title: [Experimental basis for associated subcutaneous jet injection immunization against plague and smallpox].
abstract: Experiments in guinea-pigs have indicated that combined immunization with the mixture of live plague and smallpox vaccines introduced subcutaneously by means of a jet injector are safe and faintly reactogenic. Highly intense immunity, as revealed by serological shifts and by the degree of protection of the vaccinated animals challenge with the virulent cultures of the corresponding infective agents, allows the recommendation that combined subcutaneous immunization against plague and smallpox by means of a jet injector be further studied on humans.
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D007277:Injections, Jet; D007279:Injections, Subcutaneous; D010930:Plague / Q000517:prevention & control*; D010931:Plague Vaccine / Q000008:administration & dosage*; D011817:Rabbits; D012899:Smallpox / Q000517:prevention & control*; D012900:Smallpox Vaccine / Q000008:administration & dosage*
chemical_list: D010931:Plague Vaccine; D012900:Smallpox Vaccine
vernacular_title: Eksperimental'noe obosnovanie assotsiirovannoĭ podkozhno-bezygol'noĭ immunizatsii protiv chumy i natural'noĭ ospy.