Hereditary neurologic disorders, characterized by ataxia. Immunological in vitro parameters and HLA.
Nineteen untreated patients with hereditary ataxia, hereditary spastic paraplegia and Charcot-Marie-Tooth's syndrome were investigated for immunological in vitro parameters (lymphocyte transformation with PHA, con A, PWM, antigens, determination of T- and B-lymphocytes and HLA-typing). When compared with normal controls, no significant deviation was found.
D000293:Adolescent; D000328:Adult; D001259:Ataxia / Q000235:genetics / Q000276:immunology*; D002607:Charcot-Marie-Tooth Disease / Q000235:genetics / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005838:Genotype; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation; D008875:Middle Aged; D009128:Muscle Spasticity / Q000235:genetics / Q000276:immunology; D009133:Muscular Atrophy / Q000276:immunology*; D010264:Paraplegia / Q000235:genetics / Q000276:immunology*; D010641:Phenotype
D006680:HLA Antigens