Cysteine in the manganous-isocitrate binding site of pig heart TPN-specific isocitrate dehydrogenase. I. Kinetics of chemical modification and properties of thiocyano enzyme.
D000818:Animals; D001665:Binding Sites / Q000187:drug effects; D003545:Cysteine / Q000378:metabolism*; D004228:Dithionitrobenzoic Acid / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D007521:Isocitrate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007523:Isocitrates / Q000378:metabolism*; D007700:Kinetics; D008345:Manganese / Q000378:metabolism*; D009206:Myocardium / Q000201:enzymology*; D009249:NADP; D009579:Nitrobenzoates / Q000494:pharmacology*; D011190:Potassium Cyanide / Q000378:metabolism; D013552:Swine
D007523:Isocitrates; D009579:Nitrobenzoates; D008345:Manganese; D009249:NADP; D004228:Dithionitrobenzoic Acid; D007521:Isocitrate Dehydrogenase; D003545:Cysteine; D011190:Potassium Cyanide