title: A study to determine the effect of Betadine Vaginal Cleansing Kit on cervical flora after insertion of an intra-uterine contraceptive device.
abstract: Twenty-four women with negative high vaginal swabs, who attended for insertion of an intra-uterine contraceptive device, were randomly allocated to two groups. One group used the Betadine Vaginal Cleansing Kit before and after insertion of the intra-uterine device; the other group did not use any cleansing agent. After 4 to 6 weeks, the patients were re-examined and a cervical swab was taken. The bacteriological findings were of interest and significance. In the study group there was bacterial in only one patient out of the twelve, whereas in the control group there was bacterial growth in ten out of the twelve. The bacteria grown were of doubtful clinical significance, but in certain circumstances they could take a pathogenic role. The marked absence of bacterial growth in the study group is significant because, during a 4 to 6 week period, the cervical mucus remained sterile thus minimizing the risk of pelvic infection during and immediately after insertion. Whether is has any significant effect in the long-term reduction of the incidence of pelvic infection remains to be seen, and further studies are needed.
mesh_terms: D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000517:prevention & control*; D002584:Cervix Uteri / Q000382:microbiology*; D005260:Female; D006801:Humans; D007434:Intrauterine Devices; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000494:pharmacology*; D011897:Random Allocation; D007507:Therapeutic Irrigation; D014626:Vaginal Smears
chemical_list: D011206:Povidone-Iodine; D011205:Povidone