title: [Dynamics of the immunological indices in lymphogranulomatosis following splenectomy and radiation therapy].
abstract: The dynamics of immune indices in 38 patients with Hodgkin's disease, following splenectomy and radiation therapy is discussed. The early stage of the disease is found to involve changes in immune response which become more pronounced in the course of generalization of tumor process and development of intoxication symptoms. Correlations between the frequency of spleen and lymph nodes lesions below the diaphragm, histological pattern of tumor and decline in immunological vigor are shown. Also, indications for splenectomy are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007109:Immunity; D007136:Immunoglobulins / Q000032:analysis; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D012397:Rosette Formation; D013156:Splenectomy
chemical_list: D007136:Immunoglobulins
vernacular_title: Dinamika immunologicheskikh pokazatelei u bol'nykh limfogranulomatozom posle splenéktomii i luchevoĭ terapii.