title: Epidural block with chloroprocaine during labour.
abstract: Lumbar epidural block was performed during labour in 50 healthy women, with 2% chloroprocaine in an initial dose of about 6 ml. Pain relief was achieved within 5 min and the mean duration of action was 43 min. The frequency of instrumental deliveries was lower than earlier obtained with bupivacaine. No specific adverse reactions were found in the infants. In 20 cases, serum cholinesterase activity was analysed in mothers as well as infants and found to be normal.
mesh_terms: D000293:Adolescent; D000328:Adult; D000767:Anesthesia, Epidural; D000773:Anesthesia, Obstetrical; D005260:Female; D006801:Humans; D011247:Pregnancy; D011343:Procaine / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D011343:Procaine; C004616:chloroprocaine