title: Bifurcation and resonance in a model for bursting nerve cells.
abstract: In this paper we consider a model for the phenomenon of bursting in nerve cells. Experimental evidence indicates that this phenomenon is due to the interaction of multiple conductances with very different kinetics, and the model incorporates this evidence. As a parameter is varied the model undergoes a transition between two oscillatory waveforms; a corresponding transition is observed experimentally. After establishing the periodicity of the subcritical oscillatory solution, the nature of the transition is studied. It is found to be a resonance bifurcation, with the solution branching at the critical point to another periodic solution of the same period. Using this result a comparison is made between the model and experimental observations. The model is found to predict and allow an interpretation of these observations.
mesh_terms: D000200:Action Potentials; D000818:Animals; D006801:Humans; D008954:Models, Biological; D009431:Neural Conduction; D009474:Neurons / Q000502:physiology*