[Influence of adriamycin upon the radiation effect on Chinese hamster cells (author's transl)].
During combined treatment of Chinese hamster cells in vitro with adriamycin and irradiation, there appear interactions between the two treatment modalities, V79 cells showing interaction in an additive sense, B14 cells in the sense of synergistic interaction. The capacity for interaction can persist for a long while, and even may be transmitted to the offspring of surviving cells. Treatment with adriamycin does not influence the fractionation effect or the recovery from sublethal radiation damage in the case of following fractionated irradiation.
D000818:Animals; D002477:Cells / Q000528:radiation effects*; D006224:Cricetinae; D004317:Doxorubicin / Q000494:pharmacology*; D011829:Radiation Dosage; D013997:Time Factors
D004317:Doxorubicin
Die Beeinflussung der Strahlenwirkung auf chinesische Hamsterzellen durch Adriamycin.