Coagulopathy associated with peritoneovenous shunting.
Le Veen shunts successfully alleviated ascites in 19 of 24 patients (79 percent). Clinical clotting typical of disseminated intravenous coagulation occurred in nine of these patients (37 percent) and was fatal in seven (78 percent). Laboratory findings suggesting disseminated intravenous clotting were present in five other patients (21 percent) but were not associated with troublesome bleeding. Coagulopathy was reversed in 7 of 14 patients (50 percent), if the shunt was ligated and supportive measures were taken early in the postoperative course. Failure to recognize or take immediate action resulted in progressive disseminated intravenous clotting associated with a mortality of 50 percent (7 of 14 patients).
D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005337:Fibrin / Q000378:metabolism; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010536:Peritoneovenous Shunt; D011183:Postoperative Complications / Q000209:etiology* / Q000628:therapy; D014656:Vascular Surgical Procedures
D005338:Fibrin Fibrinogen Degradation Products; D005337:Fibrin