title: Alimentary induced changes in the plasma and the liver lipoproteins.
abstract: The object of the present study are the quantitative and qualitative changes of the main plasma and liver lipoproteins (LP) under the influence of diets rich in: pure cholesterol (A); egg yolk (CEY); both cholesterol and egg yolk (AEY). The experiments were made on Wistar rats for 6 1/2 months. The data obtained indicated: 1. The A resulted in an increase of plasma VLDL-cholesterol, but the most considerable changes took place in the liver LDL, whose contents of cholesterol (Ch) and triacylglycerols (TG1) was higher than that of control group. The liver VLDL-Ch and VLDL-TG1 were quite low. In plasma and liver FFA and bulk of saturated and monounsaturated FA was increased; 2. The CEY resulted in a significant increase of the plasma LDL and VLDL-Ch as well as in a decrease of HDL-Ch without influencing significantly of FA-pattern of FFA as esterified Ch; 3. The AEY resulted in changes of plasma and liver LP which resembled either A or CEY groups, but in some cases and entirely new station was reached (e.g. a considerable decrease of HDL-Ch). However AEY-induced changes though more expressed, were more susceptible to a regression than those induced by pure cholesterol.
mesh_terms: D000818:Animals; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D004530:Egg Yolk; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008099:Liver / Q000032:analysis*; D008297:Male; D051381:Rats; D014280:Triglycerides / Q000097:blood
chemical_list: D002791:Cholesterol, Dietary; D005230:Fatty Acids, Nonesterified; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides