Metabolism of lipoproteins in rodent malaria, relationship between lipolysis, steatosis and increased biosynthesis of V.L.D.L.
The kinetic study of the seric free fatty acids, total lipids and hepatic triacyglycerides had led us to conclude that the biosynthesis of T.A.G.-rich lipoproteins increases during malaria. It seems that the parasite induces a lipolysis of adipose tissue in order to meet its own needs for fatty acids and that the excess of the latter taken by the liver involves an increased synthesis of the V.L.D.L. The cis-vaccenic acid has also been analysed during the evolution of parasitaemia; these variations by themselves cannot explain the extra parasitic hemolysis.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D002395:Catecholamines / Q000652:urine; D005227:Fatty Acids / Q000378:metabolism; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D008066:Lipolysis; D008079:Lipoproteins, VLDL / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008288:Malaria / Q000378:metabolism*; D051379:Mice; D009829:Oleic Acids / Q000032:analysis; D014280:Triglycerides / Q000378:metabolism
D002395:Catecholamines; D005227:Fatty Acids; D005230:Fatty Acids, Nonesterified; D008079:Lipoproteins, VLDL; D009829:Oleic Acids; D014280:Triglycerides; C065593:cis-vaccenic acid