Glutathione peroxidase activity in whole blood of patients with sickle cell anaemia.
Whole blood glutathione peroxidase was found significantly increased relative to controls in a group of 21 black patients with sickle cell anaemia. One control group consisted of 15 normal black subjects. A second control group, consisting of 21 black patients with various abnormal haemoglobins including alpha-thalassaemia, also showed a tendency to enhanced glutathione peroxidase activity, confirming previous reports that elevated glutathione peroxidase levels are secondary to a variety of haemolytic conditions, rather than typical of sickle cell anaemia.
D000755:Anemia, Sickle Cell / Q000201:enzymology*; D044383:Black People; D004912:Erythrocytes / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000097:blood*; D006455:Hemoglobins, Abnormal / Q000378:metabolism; D006801:Humans; D010544:Peroxidases / Q000097:blood*; D013789:Thalassemia / Q000201:enzymology
D006455:Hemoglobins, Abnormal; D010544:Peroxidases; D005979:Glutathione Peroxidase