Successful passive transfer of resistance to Fasciola hepatica infection in rats by immune serum and transfer factor.
Resistance to Fasciola hepatica was shown by a 64 per cent reduction in fluke recovery compared with control rats was recorded in rats inoculated with serum from sheep experimentally infected with F hepatica. A comparable reduction (55.6 per cent) was obtained using transfer factor prepared from lysed leucocytes of infected rats. No significant reduction was obtained using transfer factor prepared from sheep or calves.
D000818:Animals; D005211:Fascioliasis / Q000276:immunology / Q000662:veterinary*; D007106:Immune Sera / Q000276:immunology*; D007112:Immunity, Maternally-Acquired; D051381:Rats; D012376:Rodent Diseases / Q000276:immunology*; D012756:Sheep / Q000276:immunology; D014165:Transfer Factor / Q000276:immunology*
D007106:Immune Sera; D014165:Transfer Factor