[Clinical observation of serous ferritin levels in obstetrics and gynecology--relation between maternal, fetal and neonatal sera (author's transl)].
a. By the 2-site radioimmunoassay, maternal, umbilical and neonatal sera of human were measured. b. Non-heme iron contents of some organs of maternal, fetal and neonatal mice were analysed and each segment was measured. The results were as follows. 1) The serous ferritin levels of early, mid and late pregnancy were 34.1 +/- 19.0 ng/ml, 22.9 +/- 12.2 ng/ml and 19.4 +/- 11.7 ng/ml respectively in non-anemic group, while 15.1 +/- 7.8 ng/ml, 10.2 +/- 6.7 ng/ml and 5.2 +/- 2.2 ng/ml in anemic group, both decreasing in the course of the pregnancy. 2) The serous ferritin levels of umbilical cords were significantly higher than those of mothers, and no relationship was found between them. According to the maternal serous ferritin levels, grouped into (a) less than 15 ng/ml, (b) over 15 ng/ml and less than 30 ng/ml, (c) more than 20 ng/ml, significant difference of umbilical serous ferritin levels was found between in (a) (b) and in (c). 3) Serous ferritin levels of neonate increased to peak on the 4th to 5th day after birth, as the serous bilirubin levels did. 4) Non-heme iron contents of some organs of pregnant mice varied a great deal, but the SII (containing the ferritin) segment increased in the course of pregnancy and during the puerperium.
D000818:Animals; D005260:Female; D005293:Ferritins / Q000097:blood*; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D007501:Iron / Q000032:analysis; D011247:Pregnancy; D011863:Radioimmunoassay; D051381:Rats; D014018:Tissue Distribution
D005293:Ferritins; D007501:Iron