title: [Immunoglobulin levels at different ages in the healthy child population].
abstract: In this study, we report the IgE, IgA, IgM and IgG levels in the serum and the secretory IgA obtained from a group of children of different ages with normal morphgram, with no personal or family history of allergies and without recurrent infectious diseases. The IgG, IgA and IgM and salivary secretory IgA were determined by the immunonephelometry technique, using specific anti-serum for heavy chains obtained form rabbits and purified by affinitive chromatography. The IgE was determined by radioimmunoassay, using the PRIST technique. If we look at all published works about normal levels of immunoglobulins in serum, we can see many differences among the results obtained by different authors. Our results are different as well; however, there is no difference in IgE levels. In our work, the secretory IgA level cannot be compared as we do not have any other study available for comparison. We think that our results differ from those obtained by other authors because of differences in laboratory and statistical techniques and other factors such as environment, constitution, nutrition, etc.
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D007223:Infant; D009391:Nephelometry and Turbidimetry; D011864:Radioimmunosorbent Test; D012016:Reference Values; D012463:Saliva / Q000032:analysis*
chemical_list: D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D007073:Immunoglobulin E
vernacular_title: Niveles de inmunoglobulinas a distintas edades en la población infantil sana.