title: [The Steel Richardson Olszewski-syndrome. A report on 3 further cases (author's transl)].
abstract: In this report we are describing 3 further cases of progressive supranuclear palsy, all displaying the typical clinical features (first described by Steele, Richardson and Olszewski, 1964): Ophthalmoplegia (affecting chiefly vertical gaze), pseudobulbar palsy, dysarthria, dystonic rigidity of the neck and upper trunk and dementia. Clinical symptoms started between 49 and 51 years of age with slow progression during 2 to 4 years. One patient died 2 years after the first clinical symptoms began. The purpose of this paper is, to describe a further group of 3 cases of progressive supranuclear palsy and to point out in detail the clinical symptoms, that all correspond to supranuclear localisation of this disease and to report about some differences in the development of the disease and the fully developed disorder. The use of treatment with Adamantin and Akineton was not (very) satisfying.
mesh_terms: D000547:Amantadine / Q000627:therapeutic use; D001712:Biperiden / Q000627:therapeutic use; D010244:Bulbar Palsy, Progressive / Q000175:diagnosis; D003704:Dementia / Q000175:diagnosis; D004401:Dysarthria / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000188:drug therapy; D013577:Syndrome
chemical_list: D001712:Biperiden; D000547:Amantadine
vernacular_title: Progressive supranukleäre Blicklähmung. Klinischer Verlauf von drei weiteren Fällen.