Trisomy 10p produced by recombination involving maternal inversion inv(10)(pllq26).
An infant with features of trisomy 10p syndrome was found to have an abnormal chromosome 10: 46, XY, rec(10), dup p, inv(10) (p11q26) mat. The infant's mother was heterozygous for a pericentric inversion involving chromosome 10 (46, XX, inv (10) (p11q26). The infant's derivative chromosome was apparently produced by meiotic recombination between the inversion chromosome and its normal homologue.
D000015:Abnormalities, Multiple / Q000235:genetics; D007446:Chromosome Inversion; D002877:Chromosomes, Human / Q000648:ultrastructure; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D010641:Phenotype; D014314:Trisomy