Influence of levamisole treatment in old people.
Eight hospitalized people, over 77 years old, have been treated during one month with Levamisole at the dose of 150 mg a day, once a week. They have been compared to 18 controls matched for age. Levamisole raised the number of E rosettes in aged patients. This effect was found to be significant. However the increase of the percentage of E rosettes was not comparable to the percentage found in young healthy subjects. In three subjects the administration of the drug resulted in a fall of auto-antibodies noted before therapy.
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007958:Leukocyte Count; D007978:Levamisole / Q000494:pharmacology*; D012397:Rosette Formation
D001323:Autoantibodies; D007978:Levamisole