title: Delayed monensin sodium toxicity in horses.
abstract: Thirty-two horses were examined with a history of poor performance and unthriftiness several months after the ingestion of feed containing monensin sodium. Cardiac abnormality was diagnosed in 8 cases and suspected in 4 others. Necropsy examinations were performed on 6 cases with marked clinical symptoms and evidence of circulatory failure was found. Marked cardiac myopathy and fibrosis was a consistent feature. It is concluded that ingestion of monensin sodium by horses may cause either acute death or delayed cardiac circulatory failure as a result of specific cardiac myodegeneration.
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D005663:Furans / Q000009:adverse effects*; D006734:Horse Diseases / Q000139:chemically induced* / Q000473:pathology; D006736:Horses; D008985:Monensin / Q000009:adverse effects*
chemical_list: D005663:Furans; D008985:Monensin