[Pathomorphology of abortive rabies].
White random-bred mice inoculated intraperitoneally with street rabies virus were found to have numerous Babes-Negri bodies in cerebral neurons very frequently up to 5 days of the disease. On the 7-11th days of the disease the inclusions were found in some neurons in 11 of 17 mice examined. Among 24 mice with abortive rabies (recovering completely or surviving with residual symptoms such as pareses or paralysis) examined on the 20-240th days after the onset occasional Babes-Negri bodies were found either in the brain or in the spinal cord in 6 animals only. The central nervous system of these animals showed weak degenerative and inflammatory lesions; the animals had high antibody titers but yielded no virus. It is concluded that in some cases abortive infection becomes a latent one.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001921:Brain / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D005260:Female; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D009500:Neutralization Tests; D011818:Rabies / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D011820:Rabies virus / Q000302:isolation & purification; D013116:Spinal Cord / Q000473:pathology*
D000914:Antibodies, Viral
Patomorfologiia abortivnogo beshenstva.