Translocation of hepatic cytosol androgen receptor to the nucleus in vivo in male rats.
Testosterone, which was injected s.c. into adult male rats castrated 15 h prior to the injection, decreased the number of androgen-specific binding sites in the cytosol at 30 min. Coincidentally, a substantial increase was observed in the nucleus. The decreased number of the sites in the cytosol was restored to the initial level at 60 min; on the contrary, a decrease was observed in the nucleus.
D000818:Animals; D002369:Castration; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D011944:Receptors, Androgen / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism; D013997:Time Factors
D011944:Receptors, Androgen; D011987:Receptors, Steroid; D013739:Testosterone