[Experimental study of the possibility of passage of staphylococcal toxoid from mother to fetus].
After the immunization of pregnant rats with purified adsorbed staphylococcal toxoid the antigen could be detected 2-48 hours later in the parenchymatous organs (the liver, the spleen), but not in the blood serum and the amniotic fluid. The rats immunized at an early period of pregnancy showed the presence of the antigen in their placenta and fetuses, while after the immunization at a late period of pregnancy the antigen could be only seldom detected in the placenta and practically never in the fetuses. There are grounds to believe that staphylococcal toxoid does not pass from the mother to the fetus through the completely formed placenta.
D000818:Animals; D005260:Female; D007279:Injections, Subcutaneous; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control; D051381:Rats; D013203:Staphylococcal Infections / Q000517:prevention & control; D013208:Staphylococcal Toxoid / Q000008:administration & dosage*; D014018:Tissue Distribution; D014611:Vaccination
D013208:Staphylococcal Toxoid
Eksperimental'noe izuchenie vozmozhnosti perekhoda stafilokokkovogo anatoksina ot materi k plodu.