[Effect of the inhibition of thyroid function on gastric juice ionometric indices in dogs].
It has been established in experiments on dogs that inhibition of thyroid function decreases the concentration and the rate of secretion of active hydrogen and sodium ions with gastric juice excreted during histamine stimulation of gastric secretion. It has been revealed in the course of acid formation by the stomach that changes in the concentration and rate of secretion of active hydrogen and sodium ions in gastric juice were in good agreement and manifested unidirectional trends. These findings allow a conclusion about a close relationship between active hydrogen and sodium ions in acid formation by the stomach both in health and disease of thyreogenic origin. It is recommended that the characteristics of the activity, concentration of active ions in gastric juice and their secretion rate be used as criteria for gastric function.
D000818:Animals; D003864:Depression, Chemical; D004285:Dogs; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000032:analysis / Q000187:drug effects / Q000502:physiology*; D006632:Histamine / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D008713:Methimazole / Q000494:pharmacology; D012636:Secretory Rate / Q000187:drug effects; D012964:Sodium / Q000032:analysis; D013961:Thyroid Gland / Q000187:drug effects / Q000502:physiology*
D008713:Methimazole; D006632:Histamine; D012964:Sodium
Vliianie ingibirovaniia funktsii shchitovidnoĭ zhelezy na nekotovye pokazateli ionometrii zheludochnogo soka sobak.