[Blood lipoprotein cholesterol and liver hydroxylase activity in ischemic heart disease patients with normal blood lipids].
The authors examined specially selected 165 practically healthy males and 373 patients with ischemic heart disease from 20 to 59 years of age. Normolipoproteinemia (total cholesterol (CS) less than or equal to 260 ml/dl, triglycerides (TG) less than or equal to mg/dl, CH of very low density lipoproteins less than or equal to 36 mg/dl, CS of low-density lipoproteins less than or equal to 190 mg/dl) was found in 172 males with ischemic heart disease (46%). The mean content in blood serum of TG and CS of very low density lipoproteins is higher and the concentration of CS of low density lipoproteins is significantly lower in patients than in healthy individuals. Antipyrin half-life in patients is significantly increased, while the amount of bile acids and concentration of CS in bile of individuals with normolipoproteinemia do not differ from the indices in healthy persons. A relationship was shown between the body mass/height index, antipyrin half-life and concentration of CS on low density lipoproteins.
D000328:Adult; D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000378:metabolism*; D004789:Enzyme Activation; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008099:Liver / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood
D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol; D006899:Mixed Function Oxygenases
Kholesterin lipoproteidov krovi i gidroksilaznaia aktivnost' pecheni u bol'nykh ishemicheskoĭ bolezn'iu serdtsa s normolipidemieĭ.