[About the antimicrobial activity of substituted aromatic aldehydes (author's transl)].
The MIC-values and the antimicrobial activity in the paper disc diffusion method of 86 resp. 79 substituted aromatic aldehydes have been investigated. Antibacterial activity has been tested against Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris and Klebsiella pneumoniae, the antifungal activity against Trichophyton mentagrophytes, Aspergillus niger and Candida albicans. 13 classes of substituents have been investigated. The most active compounds are substituted with nitro-, hydroxy- and halogen groups.
D000447:Aldehydes / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001547:Benzaldehydes / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004352:Drug Resistance, Microbial; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D013045:Species Specificity
D000447:Aldehydes; D001547:Benzaldehydes
Zur antimikrobiellen Wirksamkeit substituierter aromatischer Aldehyde.