Essential fatty acid deficiency and evidence for arachidonate synthesis in the cat.
1. There is controversy regarding the capacity of the cat to convert 18: 2 omega 6 to 20: 4 omega 6 and the ability of the essential fatty acid (EFA)-deficient cat to produce 20: 3 omega 9. 2. This paper reports the isolation and identification of 20: 3 omega 9 from kidney phospholipids of EFA-deficient cats. 3. The results suggest that the cat is capable of limited synthesis of 20: 4 omega 6 using a delta 5- and delta 8-desaturase.
D000818:Animals; D001095:Arachidonic Acids / Q000096:biosynthesis*; D002415:Cats / Q000378:metabolism*; D005228:Fatty Acids, Essential / Q000172:deficiency*; D005231:Fatty Acids, Unsaturated / Q000096:biosynthesis; D007668:Kidney / Q000378:metabolism
D001095:Arachidonic Acids; D005228:Fatty Acids, Essential; D005231:Fatty Acids, Unsaturated