title: Conversion of 15 alpha-hydroxy-11-oxo-progesterone to 3 beta, 11 alpha, 15 beta-trihydroxy-5-pregnen-20-one.
abstract: 3 beta, 11 alpha, 15 beta-Trihydroxy-5-pregnen-20-one, an intermediate required for the synthesis of the oogoniols, has been prepared from 15 alpha-hydroxy-11-oxoprogesterone in an overall yield of 16%. The three isomers (at C-11, C-15) of the pregnene were also prepared.
mesh_terms: D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008722:Methods; D011284:Pregnenolone / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D011374:Progesterone / Q000031:analogs & derivatives*; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
chemical_list: D011374:Progesterone; D011284:Pregnenolone; C029978:3 beta,11 alpha,15 beta-trihydroxy-5-pregnen-20-one; C029979:15 alpha-hydroxy-11-oxoprogesterone