Neostigmine-responsive weakness and glomerulonephritis associated with heartworm Dirofilaria immitis infestation in a dog.
Microfilariae of Dirofilaria immitis were found in blood smears of a Dalmation which showed clinical signs of muscle weakness and membranous glomerulonephritis. The muscle weakness responded to treatment with neostigmine and the microfilariae disappeared after treatment with levamisole.
D000818:Animals; D003937:Diagnosis, Differential; D004183:Dirofilaria immitis / Q000302:isolation & purification; D004184:Dirofilariasis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000469:parasitology*; D004285:Dogs; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology / Q000469:parasitology / Q000662:veterinary*; D007978:Levamisole / Q000627:therapeutic use; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000662:veterinary; D009388:Neostigmine / Q000494:pharmacology*
D007978:Levamisole; D009388:Neostigmine