title: Delayed separation of the umbilical cord, severe widespread infections, and immunodeficiency.
abstract: Three of 4 children in a family died from infection before age one year. All 3 had delayed separation of the umbilical cord in the third week. One child was found to have defects both in specific antibody production and in neutrophil function; these were not improved by treatment with ascorbic acid or levamisole.
mesh_terms: D000917:Antibody Formation; D001424:Bacterial Infections / Q000235:genetics*; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000235:genetics* / Q000276:immunology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics*; D009504:Neutrophils / Q000276:immunology; D014470:Umbilical Cord