Constituents of West African medicinal plants. XXX. Tridictyophylline, a new morphinan alkaloid from Triclisia dictyophylla.
Triclisia dictyophylla Diels (Menispermaceae) is a woody climber indigenous to West Africa which has been used natively as a medicinal in the treatment of several ailments. Chromatography of an extract of the whole plant afforded tridictophylline (3), a new morphinan alkaloid whose structure was established by a consideration of spectral data and confirmed by x-ray crystallographic analysis. The bisbenzylisoquinoline dibenzodioxin alkaloids cocsuline (1) and trigilletimine (2) were also isolated from the same extract.
D000354:Africa, Western; D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D000700:Analgesics; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000032:analysis*
D000470:Alkaloids; D000700:Analgesics; C030377:tridictyophylline