title: Iron nutrition in Indian women at different ages.
abstract: The iron status of 320 Indian women living in Chatsworth, Durban, who had volunteered for iron absorption studies, was assessed using a number of measurements. These included: radio-iron absorption, the transferrin saturation, the serum ferritin concentration and the haemoglobin concentration. In the sample as a whole, the prevalence of iron deficiency anaemia (haemoglobin concentration less than 12 g/dl, with two or more abnormal measurements of iron status) was 14,4%. A further 26% had depleted iron stores (serum ferritin less than 12 micrograms/l) and 8,4% also had evidence of iron-deficient erythropoiesis (serum ferritin less than 12 micrograms/l and transferrin saturation below 16%). A profile of iron status based on the cumulative frequency distribution of iron stores showed that the sample, with calculated median iron stores of 150 mg and lower and upper 10 percentiles of -355 mg and 655 mg respectively, was significantly more iron deficient than a sample of women studied in Washington State, USA. Of interest was the observation that all measurements of iron status were better in the older age groups, presumably as a result of the cessation of menstruation. In addition, there was evidence that the duration of menstruation, as volunteered in a brief history, had a significant effect on several measurements of iron status. This was particularly true of the serum ferritin concentration and radio-iron absorption, both of which reflect the size of the iron stores.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D000747:Anemia, Hypochromic / Q000503:physiopathology*; D005260:Female; D005293:Ferritins / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007194:India / Q000208:ethnology; D007501:Iron / Q000097:blood / Q000378:metabolism*; D007504:Iron Radioisotopes / Q000032:analysis; D008598:Menstruation; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D013019:South Africa
chemical_list: D006454:Hemoglobins; D007504:Iron Radioisotopes; D005293:Ferritins; D007501:Iron