title: Developmental defects of the lungs.
abstract: Poor lung development was first noted on scintigraphy using 99mTc-phytate in 32 children. They had all been referred for a hepatosplenic scan but the initial circulatory phase of the radiopharmaceutical was also recorded as a routine procedure. In 3 patients it revealed aplasia of an entire lung; bilateral pulmonary hypoplasia was observed in 14 of 16 patients with diaphragmatic herniae. Six patients with congenital heart enlargement showed a poorly developed ipsilateral lung; 5 of 6 patients with dextrocardia without an intracardiac defect had a larger left lung compared with the right lung; both pulmonary beds appeared equal in a patient with mesocardia.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008168:Lung / Q000002:abnormalities* / Q000000981:diagnostic imaging; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging; D013667:Technetium
chemical_list: D015609:Organotechnetium Compounds; C026177:technetium phytate; D013667:Technetium; D010833:Phytic Acid