title: Dibutyltin oxide--phenyl isocyanate system for regioselective phenylcarbamoylation of the hydroxy-groups of ribonucleosides.
abstract: For partial phenylcarbamoylation of the hydroxy-groups of ribonucleosides, dibutyltin oxide--phenyl isocyanate system was found to be surperior to the bis(tributyltin) oxide--phenyl isocyanate system from the standpoint of reaction procedures including isolation of the products; the reaction was proved to occur with similar regioselectivity and to give the corresponding 5'-, 3'-, and 2'-O-phenylcarbamoyl derivatives in good yields, respectively, due to the conditions used.
mesh_terms: D003485:Cyanates; D007202:Indicators and Reagents; D017953:Isocyanates; D008722:Methods; D009947:Organotin Compounds; D012263:Ribonucleosides / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
chemical_list: D003485:Cyanates; D007202:Indicators and Reagents; D017953:Isocyanates; D009947:Organotin Compounds; D012263:Ribonucleosides; C025319:phenyl isocyanate; C031078:dibutyltin oxide