Drug-induced esophagitis.
We report two patients with quinidine-induced esophagitis along with a review which reveals drug-induced esophagitis to be uncommon. Certain drugs implicated time and again include tetracycline, doxycycline KCl, quinidine, clindamycin, and a British drug, emepronium. Other drugs are mentioned in isolated case reports. Most patients have a benign course, responding well to antacids and discontinuation of the responsible medication, with the exception of KCl-induced injury, which may be fatal. Taking medication with a drink of water and avoiding medications just before retiring may help prevent drug-induced esophagitis.
D000368:Aged; D002981:Clindamycin / Q000009:adverse effects; D004318:Doxycycline / Q000009:adverse effects; D004629:Emepronium / Q000009:adverse effects; D004941:Esophagitis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011189:Potassium Chloride / Q000009:adverse effects; D011802:Quinidine / Q000009:adverse effects; D013754:Tetracyclines / Q000009:adverse effects
D013754:Tetracyclines; D004629:Emepronium; D002981:Clindamycin; D011189:Potassium Chloride; D011802:Quinidine; D004318:Doxycycline