title: Lymphocyte subpopulations in multiple sclerosis: variations in rosette tests using erythrocytes from different sheep.
abstract: Lymphocytes from 34 patients with active and with stable multiple sclerosis (MS) were examined by rosetting techniques. Patients with active disease had a relative lymphopenia (35 +/- 9%). When tested with erythrocytes (E) from one out of three sheep used, patients with active MS had a decrease in E-rosette forming cells (E-RFC) compared to patients with stable disease and with healthy controls. Other tests (active E-, EAET-, EA-, and EAC-RFC) did not disclose any differences between patients and controls. The results suggest that the origin of the E may be of importance in E-RFC tests.
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D009103:Multiple Sclerosis / Q000276:immunology*; D012397:Rosette Formation / Q000379:methods; D012756:Sheep