Delayed (cellular) hypersensitivity in mice during experimental ancylostomiasis. III. Effect of longer latent period for immobilisation of challenged larvae in the adoptively immunized host.
Sensitized and normal mesenteric lymph node cells were transferred separately into three groups of recipient female swiss albino mice. Recipients that received sensitized cells and challenged at 28 days after cell transfer produced rapid and early expulsion of larvae from the gastrointestinal tract and also destroyed them in muscles. Allergic immobilisation and death of the larvae may be due to the primary role of delayed type hypersensitivity response in this mouse model.
D000724:Ancylostomiasis / Q000276:immunology*; D000818:Animals; D004064:Digestive System / Q000469:parasitology; D005260:Female; D006968:Hypersensitivity, Delayed; D007116:Immunization, Passive; D051379:Mice; D009132:Muscles / Q000469:parasitology; D013997:Time Factors