In-vivo studies on C2 organic acids in the tissues of rats injected with xylitol and glucose.
Oxalic, glyoxylic, and glycollic acid were determined in rat liver and kidney after injection with [U-14C]-xylitol or [U-14C]-glucose. Neither glucose nor xylitol led to the formation of oxalic and glyoxylic acid, yet glycollic acid was found in both tissues after injection with xylitol. Possible pathways leading from xylitol to glycollic acid are discussed.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001921:Brain / Q000378:metabolism; D005947:Glucose / Q000494:pharmacology*; D006016:Glycolates / Q000096:biosynthesis*; D006038:Glyoxylates / Q000096:biosynthesis*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D010070:Oxalates / Q000096:biosynthesis*; D051381:Rats; D014993:Xylitol / Q000378:metabolism*
D000596:Amino Acids; D006016:Glycolates; D006038:Glyoxylates; D010070:Oxalates; D005947:Glucose; D014993:Xylitol