Familial midgut anomalies--a spectrum of defects due to the same cause?
We report three familial cases with congenital midgut anomalies: a father and his daughter with congenital midgut volvulus and a consequent intestinal obstruction and father's female sib with atresia of the ascending colon. A common hypothetical cause operating at different gestational periods will be discussed along with the possible genetic implications.
D003106:Colon / Q000002:abnormalities; D005260:Female; D006801:Humans; D007082:Ileum / Q000002:abnormalities; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics*; D007415:Intestinal Obstruction / Q000235:genetics*; D007422:Intestines / Q000002:abnormalities*; D008297:Male; D010375:Pedigree