The development of metastases within a field of previous irradiation: a case report.
The development of metastatic chest wall growths from a primary nasopharyngeal carcinoma is described. The growths developed only in areas previously irradiated prophylactically and sharply outlined the treatment portals. The adjacent skin appeared completely normal. The possible mechanisms underlying this phenomenon are reviewed.
D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008482:Mediastinum; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D009381:Neoplasms, Radiation-Induced / Q000209:etiology / Q000473:pathology / Q000556:secondary*; D011878:Radiotherapy / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology / Q000556:secondary*