[Evaluation of hematometric parameters and plasma ferritin levels in patients treated with ferritin-containing preparations].
Ferritin has been administered in immediately bioavailable solution form, and in solid form, with exclusively duodenal bioavailability, to two groups of patients suffering from sideropenic dyserythropoietic anaemia. The results obtained point to a significant stimulating action on erythropoiesis documented by the increase in reticulocytes and red cells. This increase is certainly relatable to the increase of available iron and to its incorporation in the erythrocytes, as demonstrated by the increase in ferritinaemia, sideraemia, haemoglobin and mean corpuscular haemoglocbin concentration. The data obtained showed the bioavailable fluid form to be more active than the solid.
D000747:Anemia, Hypochromic / Q000097:blood / Q000188:drug therapy*; D001682:Biological Availability; D001772:Blood Cell Count; D004341:Drug Evaluation; D004909:Erythrocyte Indices / Q000187:drug effects; D004911:Erythrocyte Volume / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects; D005293:Ferritins / Q000097:blood* / Q000378:metabolism / Q000627:therapeutic use; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007501:Iron / Q000097:blood; D012156:Reticulocytes / Q000187:drug effects
D006454:Hemoglobins; D005293:Ferritins; D007501:Iron
Valutazione dei parametri ematometrici e dei livelli della ferritina plasmatica in pazienti trattati con preparati contenenti ferritina.