Experimental microsurgical model in rats preventing duodenogastric reflux. A preliminary report.
For the purpose of studying the significance of the bile and duodenal reflux into the stomach in rats we present an experimental animal model which--in contrast to the procedures reported until now--can exactly be reproduced due to the advantage of microsurgical techniques, thus reducing the operative trauma and accidental results during experimentation. The surgical procedure consists of a pylorojejunostomy with a Roux-en-y loop. This experimental model offers the possibility to discern a great deal of the problems and conditions which may be responsible in the adverse effect of bile and/or duodenal juice on the gastric mucosa.
D000818:Animals; D001655:Bile Reflux / Q000517:prevention & control*; D001660:Biliary Tract Diseases / Q000517:prevention & control*; D004195:Disease Models, Animal; D004378:Duodenal Diseases / Q000517:prevention & control*; D007583:Jejunum / Q000601:surgery; D008297:Male; D008866:Microsurgery; D011183:Postoperative Complications / Q000517:prevention & control; D011708:Pylorus / Q000601:surgery; D051381:Rats; D013272:Stomach Diseases / Q000209:etiology / Q000517:prevention & control*