title: Ammonia and amino acid metabolism y the portal-vein-drained viscera in chronic renal insufficiency.
abstract: Arterial portal-venous differences (A-PV) of ammonia (NH3) and amino acids (AA) were measured in patients with chronic renal insufficiency (CRI) and in controls. In CRI, NH3 release by the portal-vein-drained viscera (PDV) is not different from controls, Gln uptake decreases, Glu extraction occurs, Pro and Thr output increases and Ser release becomes evident; one third of N released as NH3 and AA can be accounted for by Gln and Glu uptake. The N exchange across the PDV is similar in CRI and in controls.
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000097:blood*; D000641:Ammonia / Q000097:blood*; D001158:Arteries; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D008875:Middle Aged; D011169:Portal Vein
chemical_list: D000596:Amino Acids; D000641:Ammonia