Cytapheresis in a patient with Sezary syndrome.
A patient with Sezary syndrome underwent cytapheresis on the IBM 2997 cell separator. Four procedures were performed over a 12-day period. A total of 8.3 x 10(10) Sezary cells were removed. The patient's skin lesions and lymphadenopathy regressed. Transient thrombocytopenia occurred, requiring platelet transfusion. Although a significant number of platelets were removed by pheresis, this was not sufficient to explain the thrombocytopenia. The patient subsequently died of causes unrelated to the cytapheresis.
D002469:Cell Separation; D005260:Female; D006801:Humans; D008875:Middle Aged; D012751:Sezary Syndrome / Q000473:pathology / Q000628:therapy*; D013997:Time Factors