Brain monoamine oxidase activity in schizophrenics and controls.
Postmortem samples of caudate nucleus and frontal cortex from schizophrenic, schizophrenic-like, and control subjects were examined for monoamine oxidase activity using dopamine, phenylethylamine, and 5-hydroxytryptamine as substrates. There were no significant differences between the diagnostic groups with any of the three substrates. Neither was there a difference between the sexes, nor a consistent relationship of enzyme activity to age.
D000368:Aged; D001921:Brain / Q000201:enzymology*; D002421:Caudate Nucleus / Q000201:enzymology; D005260:Female; D005625:Frontal Lobe / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000378:metabolism*; D010627:Phenethylamines / Q000378:metabolism; D012559:Schizophrenia / Q000201:enzymology*; D012701:Serotonin / Q000378:metabolism
D007527:Isoenzymes; D010627:Phenethylamines; D012701:Serotonin; D008995:Monoamine Oxidase