title: [On the calculation and the evaluation of combinations of active substances (author's transl)].
abstract: A survey is given of publications on the calculation of the combined effects of bioactive substances and on the statistical analysis of the results from combination studies. The dose-response relationships for the two essential types of combination, the independent and the equivalent mode of action, are stated and explained by typical classes of dose-response equations.
mesh_terms: D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004341:Drug Evaluation; D013223:Statistics as Topic
chemical_list: D004338:Drug Combinations
vernacular_title: Zur Berechnung und Bewertung von Wirkstoffkombinationen.