title: [Autoantibodies in advanced old-age].
abstract: A variety of autoantibodies (anti-nuclear, anti-mitochondrial, anti-smooth muscle, anti-gastric parietal cell) were measured by indirect immunofluorescence. At least one of such autoantibodies was detected in 65.2% of 46 old people sera (ranging from 76 to 95). Both a decrease in the efficiency of the immune response and a failure of the immunoregulatory mechanisms occurring with age may account for the above findings.
mesh_terms: D000368:Aged; D000375:Aging; D001323:Autoantibodies / Q000096:biosynthesis*; D006801:Humans
chemical_list: D001323:Autoantibodies
vernacular_title: Autoanticorpi nell'eta' avanzata.