title: [Closure of recurrent perforations of the tympanic membrane by means of cialit-conserved fascia and human fibrin tissue adhesive (author's transl)].
abstract: In 20 patients with recurrent perforations of the tympanic membrane after tympanoplasties the membrane defect was closed by using cialit-conserved temporal fascia and human fibrin tissue adhesive. The defects differed in size from 2 mm up to a subtotal defect. In 19 cases there was increasing vascularisation from the perforation margins towards the transplant centre after 4 weeks. After 8 weeks the connection between the transplant and the surrounding tissue was so tight that tympanometry could be performed using pressures up to 300 mmWS without any damage. Only in 1 case there was an infection. We had to remove the transplant. In comparison with the method of using only human fibrin tissue adhesive to close recurrent perforations, this method has the advantage that even bigger perforations of the tympanic membrane can be closed. The number of recurrencies of perforation also is lessened.
mesh_terms: D005205:Fascia / Q000637:transplantation*; D005337:Fibrin / Q000627:therapeutic use*; D006801:Humans; D011183:Postoperative Complications / Q000601:surgery; D012008:Recurrence; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014182:Transplantation, Autologous; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D014014:Tissue Adhesives; D005337:Fibrin
vernacular_title: Verschluss von Rezidivperforationen des Trommelfelles mit cialit-konservierter Faszie und humanem Fibrinkleber.