Prenatal detection of Turner's syndrome in conjunction with trisomy 20 mosaicism (45,X/46, X, +0).
A case of Turner's syndrome, detected antenatally and complicated by the finding of trisomy 20 mosaicism in 50% of cells from each of two amniotic fluid cultures, is described. Cultures from seven fetal tissues in the subsequent abortus showed a predominance of 45,X cells, but nevertheless suggested the existence of a very low level of trisomy 20 mosaicism in three fetal tissues. The diagnostic dilemma in interpreting trisomy 20 mosaicism is discussed.
D000328:Adult; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D002903:Chromosomes, Human, 19-20; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014314:Trisomy; D014424:Turner Syndrome / Q000175:diagnosis*