The effect of platelet poor plasma serum on endothelial cell spreading.
In this study the effects of platelet poor plasma serum (PPPS) on the in-vitro spreading of trypsinized procine aortic endothelial cells (EC) was investigated. EC cultured in porcine PPPS spread more slowly on glass coverslips than did cells cultured in procine whole blodd serum (WBS). EC cultured in PPPS adhered to the glass as well as those in WBC and grew equally well in PPPS and in WBS. The results suggest that PPPS may be deficient in a substance which is necessary for prompt spreading of EC.
D000818:Animals; D001011:Aorta / Q000166:cytology*; D001790:Blood Physiological Phenomena; D001792:Blood Platelets / Q000502:physiology*; D002465:Cell Movement; D004727:Endothelium / Q000166:cytology; D066298:In Vitro Techniques; D013552:Swine