title: [Blood coagulation in immersion in high altitudes].
abstract: At sea level, a group of four volunteers performed 20 m dives, three more hyperventilated on 12% O2 in N2 for 12 min and held their breaths for the longest time possible. All subjects were civilian sport divers. Hematocrit, hemoglobin, 2,3-DPG, plasma fibrinogen, prothrombin, alfa 1-antitrypsin, antithrombin III, plasminogen and whole-Blood Coagulation Time (BCT) were measured. 2,3-DPG was increased during high altitude permanence. Post-dive BCT was lenghtened (39%) at high altitude and shortened (30%) at sea level. No difference in BCT was detected after hypoxia hyperventilation. The results suggest that in chronic hypoxia biochemical and functional modifications take place in the blood affecting the length of BCT.
mesh_terms: D000328:Adult; D000531:Altitude; D001777:Blood Coagulation; D004242:Diving; D006801:Humans; D007101:Immersion; D008297:Male; D013550:Swimming
vernacular_title: La coagulazione del sangue nell'immersione alle grandi altezze.