Correlation between the placental and fetal body weight and size of the rat fetuses affected by intra-uterine administration of neuromuscular blocking agents.
The data from previous experimental work were analysed and indicated a positive correlation between the placental weight and fetal weight and placental size and fetal size of the rat fetuses affected by intra-uterine administration of neuromuscular blocking agents. Various factors capable of affecting the fetal size and weight were considered. The results tend to support the view that a transient period of reduction in placental blood flow, during the temporary paralysis of affected fetuses, caused their growth retardation and corresponding decrease in the size and weight of their placentae.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D005260:Female; D005317:Fetal Growth Retardation / Q000139:chemically induced; D005333:Fetus / Q000033:anatomy & histology / Q000187:drug effects*; D007511:Ischemia / Q000139:chemically induced; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects*; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology* / Q000098:blood supply; D011247:Pregnancy; D051381:Rats
D009466:Neuromuscular Blocking Agents