Circadian rhythm in pineal methionine S-adenosyltransferase.
The circadian rhythm of methionine S-adenosyltransferase, which catalyzes the formation of S-adenosylmethionine, a cosubstrate for melatonin in the pineal gland, follows the pattern of hydroxyindole-O-methyltransferase. Around the middle of the dark period, methionine S-adenosyltransferase and hydroxyindole-O-methyltransferase appear to be elevated by 2.5- and 1.5-fold, respectively, and tend to fall back during the light period.
D000121:Acetylserotonin O-Methyltransferase / Q000502:physiology; D000818:Animals; D002940:Circadian Rhythm; D008297:Male; D008716:Methionine Adenosyltransferase / Q000502:physiology*; D010870:Pineal Gland / Q000201:enzymology*; D051381:Rats; D014166:Transferases / Q000502:physiology*
D014166:Transferases; D000121:Acetylserotonin O-Methyltransferase; D008716:Methionine Adenosyltransferase