Suprasellar germinoma: an unusual clinical presentation.
A case is described of suprasellar tumor with diabetes insipidus, diminishing visual acuity, inferior bitemporal quadrantanopia, and hypopituitarism in a 19-year-old man. Computerized tomographic scan of the brain after contrast injection demonstrated periventricular enhancement. Diagnosis of germinoma was made on the basis of clinical and radiographic information and a biopsy that revealed malignant cells. The tumor responded well to radiation therapy. Diagnostic difficulties were created by systemic manifestations unrelated to endocrinopathy. Pertinent literature is reviewed.
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000532:radiotherapy; D003919:Diabetes Insipidus / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D008297:Male; D010870:Pineal Gland; D010871:Pinealoma / Q000150:complications / Q000175:diagnosis* / Q000532:radiotherapy; D014786:Vision Disorders / Q000209:etiology