[The influence of premature rupture of the membranes on fetal lung maturity (author's transl)].
In 19 cases of premature rupture of the membranes between the 30th and 37th week of gestation amniotic fluid was collected immediately after rupture of the membranes and within 72 hours for surface tension measurement in the Wilhelmy-balance. The initial values predicted lung immaturity for the fetus in all cases. Surface activity of the amniotic fluid increased in 17 women, in 2 cases however there was no difference in the surface tension values 48 hours after rupture of the membranes. These two infants developed a respiratory distress syndrome (RDS), one of them died. The pulmonary function of all neonates could be predicted correctly on the basis of the surface tension measurement of the amniotic fluid samples collected before birth. The findings support the positive effect of premature rupture of the membranes on induction of pulmonary maturity in the newborn, which leads to a reduction of RDS frequency after premature rupture of the membranes.
D000649:Amniocentesis; D000653:Amniotic Fluid / Q000032:analysis; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000150:complications*; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011379:Prognosis; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology*; D013500:Surface Tension
Der Einfluss des vorzeitigen Blasensprunges auf die fetale Lungenreifung.