Dacarbazine-induced photosensitivity reaction.
Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should instruct patients to avoid solar exposure following infusions of this drug.
D000368:Aged; D003606:Dacarbazine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000188:drug therapy; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy
D003606:Dacarbazine