title: Effects of copper on the sabellid polychaete, Eudistylia vancouveri. II. Copper accumulation and tissue injury in the branchial crown.
abstract: Copper in seawater caused injury to the radioles (gills) of the sabellid polychaete, Eudistylia vancouveri. Light and electron microscopy showed the loss of cellular adhesion and the structural derangement that lead to cell necrosis and death. The progression of injury was related to the uptake of copper into the tissues. Copper was found by X-ray microanalysis to be localized subcellularly in membrane-bound vesicles that are similar to lysosomes. Cell breakdown may result from lysosomal labilization.
mesh_terms: D000818:Animals; D003300:Copper / Q000378:metabolism / Q000494:pharmacology*; D005880:Gills / Q000187:drug effects* / Q000378:metabolism; D008854:Microscopy, Electron; D011077:Polychaeta / Q000187:drug effects* / Q000648:ultrastructure
chemical_list: D003300:Copper