The evolution of a valved hepatoduodenal intestinal conduit.
Ascending cholangitis remains among the most serious complications following operations for biliary disorders. The bacterial count of refluxing intestinal contents can be reduced by using an enteric conduit from the biliary tract to the relatively sterile duodenum. A valvular conduit prohibits reflux of intestinal contents and permits unobstructed antegrade flow of bile. This can be created by intussuscepting approximately 1 cm of intestine in the midportion of the conduit. During the last 3 yr, valvular conduits were created in 11 patients. Seven of these children were treated for biliary atresia, and 4 had operations for choledochal duct cysts. There have been no deaths or morbidity resulting from the use of the valvular conduits. The postoperative courses in these patients indicate that the use of an intussusception valve may be beneficial in the prevention of ascending cholangitis.
D000818:Animals; D001652:Bile Ducts / Q000002:abnormalities / Q000601:surgery; D001660:Biliary Tract Diseases / Q000151:congenital / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D002761:Cholangitis / Q000209:etiology; D004285:Dogs; D005260:Female; D006801:Humans; D008722:Methods; D011183:Postoperative Complications