title: [Sulfalene circulation in kidney disease patients].
abstract: Examinations of patients suffering from chronic nephritis with the nephrotoxic syndrome and amyloidosis of the kidneys with unchanged glomerular filtration showed that the rate of sulfalen excretion in the patients with the kidney diseases was higher than that in the persons of the control group. The sulfalen elimination rate and the plasmatic clearance in such patients were higher. The higher rate of sulfalen elimination was due to increased excretion of the unchanged drug with urine.
mesh_terms: D000328:Adult; D005260:Female; D005609:Free Radicals; D006801:Humans; D007674:Kidney Diseases / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D013415:Sulfalene / Q000032:analysis / Q000378:metabolism*; D013424:Sulfanilamides / Q000378:metabolism*; D013607:Tablets; D013997:Time Factors
chemical_list: D005609:Free Radicals; D013424:Sulfanilamides; D013607:Tablets; D013415:Sulfalene
vernacular_title: Tsirkuliatsiia sul'falena u bol'nykh zabolevaniiami pochek.