title: [Cimetidine for preventing the adverse effects of aspiration during anaesthesia (author's transl)].
abstract: The aspiration of gastric contents into the bronchial tree is a serious complication in both anaesthetic practice and obstetrics. The main factor in the pathophysiology of this syndrome is the degree of acidity of the aspirated material. A reliable and effective way of preventing its occurrence is to raise the pH of the gastric secretion by administration of the histamine H2 antagonist cimetidine.
mesh_terms: D000293:Adolescent; D000328:Adult; D000768:Anesthesia, General / Q000379:methods*; D002927:Cimetidine / Q000627:therapeutic use*; D005260:Female; D005750:Gastric Juice / Q000032:analysis; D005773:Gastroscopy; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D011015:Pneumonia, Aspiration / Q000517:prevention & control*
chemical_list: D006146:Guanidines; D002927:Cimetidine
vernacular_title: Prophylaxe des Säure-Aspirationssyndroms mittels Cimetidin.