[Nomographic representation of McLachlan's statistics for the analysis of local similarity between amino acid sequence].
Using McLachlan's method of probability calculation and amino acid compositions of 108 protein families, the changeability of probability distribution of local similarity of amino acid sequences on the composition of the sequences has been investigated. Probability distributions were shown to have high degrees of constancy and nearly coincide with the distribution corresponding to the composition averaged upon all families. Using this average composition, cumulative probability distributions corresponding to sequence regions compared (of 3, 4, ..., 50 residues long) have been calculated and draws for "unitary", "genetic", "physico-chemical" and "evolutionary" matrices of amino acid similarity. These statistical nomogramms may be employed for quick non-computer evaluation of the significance of local amino acid similarity.
D000595:Amino Acid Sequence; D005075:Biological Evolution; D011336:Probability; D011506:Proteins; D013329:Structure-Activity Relationship
D011506:Proteins
Normograficheskoe predstavlenie statistiki Maklaklana dlia analiza lokal'nogo skhodstva aminokislotnykh posledovatel'nosteĭ.