title: [Studies on adenocarcinoma and mixed carcinoma of the uterine cervix (author's transl)].
abstract: It is known that among the types of cervical cancers three are those which were usually called mixed cancers that indicate various transitional images between pure adenocarcinoma and pure epidermoid carcinoma. No definition for such cancer but mechanism of its histogenesis or its biological nature has been established. From this stand point of view I investigated the tissue and cytological specimens of 284 cases of cervical cancer, and obtained results as follow. 1) The number of tumors showing glandular structure, even if only to a very minor degree, accounted for 32.8% of all frank invasive cancers. On the other hand, tumors with positive mucous reaction made up 61.7%. 2) The frequency of positive mucous reaction increased in relation to the invasion depth. 3) It seems that mixed cancers are derived from three mechanisms--the acanthomatous change from pure adenocarcinoma, the collision of two types cancer and the bipotential differentiation of the same original cells. 4) It may be said that the detailed classification and investigation of cancer cells as observed in cytological specimens may serve to some extent as a clue to the estimation of glandular characteristics of cancer tissues.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears