[Combined treatment of non-small cell carcinoma of the lung with radiotherapy and moderate whole-body hyperthermia (author's transl)].
Nine patients suffering from non oat cell carcinoma bronchial carcinomas were treated with extended-field irradiations. The treatment was executed under the conditions of whole-body hyperthermia. All patients had inoperable but not yet disseminated carcinomas, seven among them a squamous cell carcinoma and two an undifferentiated carcinoma. The hyperthermia was produced by a Siemens cabin (chamber of Pomp) with preheated air of 55 to 60 degrees C and a radio frequency of 27 MHz, 400 W. A temperature of body cavities of 40 to 40.5 degrees C was reached within 40 to 60 minutes. Fifteen minutes after having reached this temperature, the patient was irradiated. The nominal standard dose of 18 to 18.5 Gy was fractioned into three times three Gy per week. Three to thirteen single doses were combined with whole-body hyperthermia. The initial tumor regression seemed increased. One patient became operable; he was submitted to pneumonectomy. All patients showed partial remissions. Compared to radiotherapy alone, there is no improvement of remission period and survival time until now. Better results could possibly be reached by an additional systemic chemotherapy.
D000328:Adult; D000368:Aged; D001984:Bronchial Neoplasms / Q000532:radiotherapy* / Q000601:surgery / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000628:therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage
Kombinierte Behandlung nichtkleinzelliger Bronchialkarzinome mit Strahlentherapie und moderater Ganzkörper-Hyperthermie.