Alimentary induced changes in the plasma and the liver lipoproteins.
The object of the present study are the quantitative and qualitative changes of the main plasma and liver lipoproteins (LP) under the influence of diets rich in: pure cholesterol (A); egg yolk (CEY); both cholesterol and egg yolk (AEY). The experiments were made on Wistar rats for 6 1/2 months. The data obtained indicated: 1. The A resulted in an increase of plasma VLDL-cholesterol, but the most considerable changes took place in the liver LDL, whose contents of cholesterol (Ch) and triacylglycerols (TG1) was higher than that of control group. The liver VLDL-Ch and VLDL-TG1 were quite low. In plasma and liver FFA and bulk of saturated and monounsaturated FA was increased; 2. The CEY resulted in a significant increase of the plasma LDL and VLDL-Ch as well as in a decrease of HDL-Ch without influencing significantly of FA-pattern of FFA as esterified Ch; 3. The AEY resulted in changes of plasma and liver LP which resembled either A or CEY groups, but in some cases and entirely new station was reached (e.g. a considerable decrease of HDL-Ch). However AEY-induced changes though more expressed, were more susceptible to a regression than those induced by pure cholesterol.
D000818:Animals; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D004530:Egg Yolk; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008099:Liver / Q000032:analysis*; D008297:Male; D051381:Rats; D014280:Triglycerides / Q000097:blood
D002791:Cholesterol, Dietary; D005230:Fatty Acids, Nonesterified; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides