title: Nephrotic syndrome due to preeclamptic nephropathy associated with a transitional mole with coexistence fetus.
abstract: An unusual case of nephrotic syndrome secondary to preeclamptic nephropathy is documented. The preeclampsia was associated with a transitional mole with coexistent fetus. A review of the literature revealed only one similar case reported previously. Immuno-pathologic examination of the renal biopsy revealed abundant IgM and fibrinogen within the glomeruli; electron microscopy showed numerous subendothelial and occasional intramesangial deposits of electron-dense material. The significance of these findings with regard to the pathogenesis of preeclamptic nephropathy is briefly discussed.
mesh_terms: D000328:Adult; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications*; D007075:Immunoglobulin M; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000473:pathology; D010920:Placenta / Q000473:pathology; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000150:complications*
chemical_list: D007075:Immunoglobulin M