title: Cognitive deficit and the unity of brain organization: Goldstein's perspective updated.
abstract: Goldstein's ideas resolve the paradox of functional specialization within an integrated brain. Conceiving the human brain as a differentiated network, we show how some of his generalizations can be operationalized, and we review some experimental tests. The results encourage us to view cerebral symptomatology as often representing not loss but suppression of abilities by lesion-induced bias in brain organization. We discuss remedial methods that might help latent abilities reassume control over behavior.
mesh_terms: D000375:Aging; D001041:Aphasia, Wernicke / Q000503:physiopathology; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000293:injuries; D002561:Cerebrovascular Disorders / Q000503:physiopathology; D003071:Cognition / Q000502:physiology*; D005246:Feedback; D007839:Functional Laterality; D006801:Humans; D008569:Memory Disorders / Q000503:physiopathology / Q000628:therapy; D008606:Mental Processes / Q000502:physiology*; D008959:Models, Neurological; D009433:Neural Inhibition