IgG and other proteins associated with human carcinomas and cancer-free tissue from the same organs.
Eluates of different were prepared at 56 degrees C using a continuous flow technique. More IgG and other serum proteins were found in liver from patients with non-malignant diseases than in liver tissue from healthy control individuals. Cancer-free liver tissue from patients with carcinomas was similar to that of patients with non-malignant diseases, but liver metastases contained twice the amount of IgG. No differences were found between non-perfused carcinomas of the kidney and cancer-free renal tissue, whereas more IgG was present in perfused carcinomas of the kidney than in cancer-free renal tissue. Most eluates of the malignant tissues and of the cancer-free renal tissue showed a reduced ratio of albumin IgG compared to that of serum or extracts, indicating a binding of IgG to antigens and/or receptors.
D001798:Blood Proteins / Q000032:analysis / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007668:Kidney / Q000276:immunology; D007680:Kidney Neoplasms / Q000276:immunology; D008099:Liver / Q000276:immunology; D008113:Liver Neoplasms / Q000276:immunology; D009363:Neoplasm Proteins / Q000032:analysis*; D009369:Neoplasms / Q000276:immunology*
D001798:Blood Proteins; D007074:Immunoglobulin G; D009363:Neoplasm Proteins