title: B-cells of the synovial membrane. III. Relationship with the specific collagenous structure of the intimal interstitium in the mouse.
abstract: An ultrastructural study of the synovial membrane in mice revealed that, in addition to specific polypeptide-producing secretory cells (B-cells), the intima is characterized by a specific differentiation of the interstitium adjacent to the synovial cavity. Scattered collagen fibrils are embedded in a fine fibrillar material, which often appears as cross-striated strands resembling long-spacing-collagen (periodicity from 90 to 120 nm). Similar material was found along the synovial cavity in the rat, guinea pig, rabbit and man. The close relationship between this material and B-cells observed in the mouse suggests that the maintenance of the specialized intimal interstitium may depend on the secretory function of B-cells.
mesh_terms: D000818:Animals; D003094:Collagen; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D011817:Rabbits; D051381:Rats; D013583:Synovial Membrane / Q000166:cytology* / Q000502:physiology
chemical_list: D003094:Collagen