title: Antigen-induced non-specific suppressor factor in sheep efferent lymph is prostaglandin E2.
abstract: Efferent lymph from the popliteal node of sheep challenged with antigen was found to suppress the in vitro transformation of sheep peripheral blood lymphocytes to a variety of antigens. The suppressor factor appeared 6-20 hr after challenged of the node and was shown to be prostaglandin E2, probably complexed to albumin.
mesh_terms: D000818:Animals; D000941:Antigens / Q000276:immunology; D005591:Chemical Fractionation; D002846:Chromatography, Affinity; D007165:Immunosuppression Therapy; D008196:Lymph / Q000032:analysis / Q000276:immunology*; D008213:Lymphocyte Activation; D011458:Prostaglandins E / Q000032:analysis / Q000276:immunology*; D012756:Sheep; D014373:Tuberculin / Q000276:immunology
chemical_list: D000941:Antigens; D011458:Prostaglandins E; D014373:Tuberculin