[Heterozygote thalassemias screening. Contribution of data analysis methods (author's transl)].
In order to reduce the cost of a systematic heterozygote thalassemias screening, and using a discriminant analysis, the authors propose a pre-selection performed on the erythrocytometric data. In the present conditions of applicability, the methodology we used appears to be very efficient in the pre-screening process. An electrophoresis with the determination of hemoglobin A2 is then carried out on the pre-selected individuals as a confirmation of the diagnosis.
D000293:Adolescent; D001797:Blood Protein Electrophoresis / Q000191:economics; D004906:Erythrocyte Count; D005260:Female; D014943:Global Health; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D008297:Male; D013789:Thalassemia / Q000097:blood* / Q000235:genetics
D006454:Hemoglobins
Le dépistage des thalassémies hétérozygotes. Apport de méthodes d'analyse de données.