title: A practical approach to management of lithium concurrent with hyponatremia, diuretic therapy and/or chronic renal failure.
abstract: Lithium therapy concurrent with hyponatremia, thiazides and possibly other diuretics and/or chronic renal failure has generally been avoided. However, despite greater risk for lithium toxicity, such combinations are feasible with appropriate precautions, especially lower lithium dosage and closer follow-up. Under the right circumstances hyponatremia, diuretics, and/or chronic renal failure are only relative lithium contraindications.
mesh_terms: D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy*; D004232:Diuretics / Q000627:therapeutic use*; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000150:complications / Q000188:drug therapy*; D007676:Kidney Failure, Chronic / Q000150:complications / Q000188:drug therapy*; D008094:Lithium / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D004232:Diuretics; D008094:Lithium