[Aspects of liver damage after experimental administration of some drugs. Preliminary note].
Rabbits treated with therapeutical dosages of five widely prescribed drug (indomethacin, isoniazid, lorazepam, tolbutamide, clofibrate) show ultrastructural changes within live cells which are inhibited by concomitant administration of silymarin.
D000818:Animals; D002994:Clofibrate / Q000009:adverse effects; D005419:Flavonoids / Q000494:pharmacology*; D007213:Indomethacin / Q000009:adverse effects; D007538:Isoniazid / Q000009:adverse effects; D008099:Liver / Q000187:drug effects* / Q000648:ultrastructure; D008140:Lorazepam / Q000009:adverse effects; D011817:Rabbits; D012838:Silymarin / Q000494:pharmacology*; D014044:Tolbutamide / Q000009:adverse effects
D005419:Flavonoids; D012838:Silymarin; D014044:Tolbutamide; D002994:Clofibrate; D008140:Lorazepam; D007538:Isoniazid; D007213:Indomethacin
Aspetti del danno epatico dopo somministrazione sperimentale di alcuni farmaci. Nota preliminare.