[Carcinoma of the pancreas with amyloid stroma and calcitonin secretion : ultrastructural study (author's transl)].
The authors report a case of anaplastic carcinoma with amyloid stroma, accompanied by the secretion of calcitonin, detected in a cervical lymph node and initially interpreted as being a metastasis from a medullary carcinoma of the thyroid. The actual pancreatic origin of the malignant tumour was proved only during the advanced stages. Ultrastructural study confirmed the endocrine nature of the tumour (neurosecretory granules). Despite its exceptional character, the existence of such a tumour is not surprising, if one accepts the concept of a diffuse endocrine system.
D002116:Calcitonin / Q000378:metabolism*; D002277:Carcinoma / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure*
D002116:Calcitonin
Carcinome pancréatique à stroma amyloïde avec sécrétion de calcitonine. Etude ultrastructurale.