Multifactorial etiology of nasal polyps.
Forty patients with nasal polyps were assessed. Elevated serum total IgE levels in nine patients did not correlate with skin testing. Increased serum immune complexes were detected in 11 patients but did not correlate with depressed complement (five patients). Multiple immunological mechanisms may be involved in nasal polyp formation.
D000402:Airway Obstruction / Q000276:immunology; D000936:Antigen-Antibody Complex; D001241:Aspirin / Q000009:adverse effects; D003165:Complement System Proteins / Q000172:deficiency; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis; D008173:Lung Diseases, Obstructive / Q000276:immunology; D009298:Nasal Polyps / Q000209:etiology* / Q000276:immunology; D012882:Skin Tests
D000936:Antigen-Antibody Complex; D007073:Immunoglobulin E; D003165:Complement System Proteins; D001241:Aspirin