[Study on phototoxicity and photoallergy of a preparation containing 10 p. 100 benzoyl peroxide after topical application on guinea-pigs (author's transl)].
Attention is focused on benzoyl peroxide as a possible phototoxic derivate. To ascertain this activity, the compound, in a pharmaceutical composition, was tested by skin painting on guinea-pigs. The preparation, containing 10 p. 100 benzoyl peroxide, was applied topically. Irradiation was carried out by an artificial source of UVA and UVB.
D000818:Animals; D001585:Benzoyl Peroxide / Q000008:administration & dosage / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced; D004890:Erythema / Q000139:chemically induced; D006168:Guinea Pigs; D008297:Male; D010545:Peroxides / Q000494:pharmacology*; D010787:Photosensitivity Disorders / Q000139:chemically induced; D012867:Skin / Q000187:drug effects*; D014466:Ultraviolet Rays
D010545:Peroxides; D001585:Benzoyl Peroxide
Recherche chez le cobaye des pouvoirs phototoxique et photoallergique du peroxyde de benzoyle à 10 P. 100 appliqué localement.