Circadian variation in plasma prolactin, gonadotropins, and testosterone in diabetic male patients with and without impotence.
The circadian variation in plasma levels of prolactin, gonadotropins, testosterone, and glucose were studied in 10 young diabetic male patients. Four patients were asymptomatic without sexual dysfunction and six patients had organic impotence. The results of this study indicate that diurnal levels of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone are similar in diabetic patients with and without impotence. During the nocturnal period, a sleep-related increase in plasma prolactin levels was noted in diabetic patients without impotence. In diabetic patients with impotence, plasma prolactin levels were similar during the diurnal and nocturnal periods. These results further support previous findings that diabetic patients with organic impotence do not have abnormal gonadotropin and testosterone levels.
D000328:Adult; D000375:Aging; D001786:Blood Glucose; D002940:Circadian Rhythm; D003920:Diabetes Mellitus / Q000097:blood; D007172:Erectile Dysfunction / Q000097:blood; D006062:Gonadotropins / Q000097:blood*; D006801:Humans; D008297:Male; D011388:Prolactin / Q000097:blood*; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D001786:Blood Glucose; D006062:Gonadotropins; D013739:Testosterone; D011388:Prolactin