title: Structural organization of nascent transcripts and hnRNA molecules in amphibian oocytes.
abstract: Comparisons of relative lengths of lampbrush loops, nascent RNP transcripts and hnRNA molecules from oocytes of amphibia with different C-values show that there is an increasing trend in loop, and transcriptional unit, length with increase in genome size but no increasing trend with respect to RNA contour length. The formation of duplex regions and circles in RNP fibrils indicates that RNA processing may occur within the nascent fibrils. The hnRNA molecules from oocytes of the various amphibia readily form intermolecular duplex structures. These complementary sequences have a low kinetic complexity and are transcribed from highly repetitive sequences distributed throughout the genome. Their possible function is considered.
mesh_terms: D000818:Animals; D005260:Female; D009865:Oocytes / Q000378:metabolism*; D009866:Oogenesis; D010063:Ovum / Q000378:metabolism*; D012332:RNA, Heterogeneous Nuclear / Q000378:metabolism*; D014158:Transcription, Genetic; D014562:Caudata; D014982:Xenopus laevis
chemical_list: D012332:RNA, Heterogeneous Nuclear