title: Fc rosette inhibition by serum of patients with infective endocarditis.
abstract: The inhibition of lymphocyte Fc rosette formation was studied in sera of patients with infective endocarditis. The pretreatment value of sensitised chicken erythrocyte (EA) rosette inhibition was 37.9 +/- 7.8%; in controls it was 4.1 +/- 1.3% (P less than 0.001). The posttreatment value was 2.8 +/- 2.1%. Six patients had culture-negative infective endocarditis, and in them the value of EA rosette inhibition was higher than in the others (42.3 +/- 7.1%). The measurement of circulating immune complexes may be a diagnostic tool in patients with culture-negative infective endocarditis.
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis*; D004697:Endocarditis, Bacterial / Q000276:immunology*; D006801:Humans; D012397:Rosette Formation
chemical_list: D000936:Antigen-Antibody Complex