title: Sensitive gas chromatographic determination of trifluoperazine in human plasma.
abstract: Plasma trifluoperazine levels of patients taking a single 20 mg dose of trifluoperazine were measured by a sensitive and linear method. The low detection limit of 0.1 ng/ml plasma was obtained through use of a highly sensitive nitrogen-phosphorus detector combined with an efficient extraction method. Recovery of trifluoperazine to human plasma was 96%. Data are presented on the stability of trifluoperazine in refrigerated human plasma.
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D006801:Humans; D013997:Time Factors; D014149:Tranquilizing Agents / Q000097:blood; D014268:Trifluoperazine / Q000097:blood* / Q000627:therapeutic use
chemical_list: D014149:Tranquilizing Agents; D014268:Trifluoperazine