[Colony-forming activity of stromal precursors of bone marrow mechanocytes in leukemia and hematopoietic hypoplasia].
The colony-forming precursors of stromal mechanocytes do not remain intact in blood diseases affecting hemopoietic stem cells (acute leukemia and hemopoiesis hypoplasia). These cells are deranged to the greatest degree in hemopoiesis hypoplasia. The drug-induced hempoiesis hypoplasia (cytostatic therapy) is characterized by a greater inhibition of the stromal precursors of mechanocytes with the same degree of myeloid hemopoiesis inhibition as in an idiopathic one.
D000208:Acute Disease; D000741:Anemia, Aplastic / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology*; D002648:Child; D003114:Colony-Forming Units Assay; D006801:Humans; D007938:Leukemia / Q000473:pathology*
Kolonieobrazuiushchaia aktivnost' stromal'nykh predshestvennikov mekhanotsitov kostnogo mozga pri leĭkozakh i gipoplaziiakh krovetvoreniia.