title: Colon perforation during attempted barium enema reduction of intussusception.
abstract: In reviewing the records of almost 1000 infants and children with intussusception in two children's hospitals over the last 25 yr, there have been seven bowel perforations during attempted hydrostatic barium enema reduction of an intussusception. Except for one instance, these have all occurred during the last 6 yr. The infants were all 6 mo old or less and most had a preceeding viral illness. Only 4 of the 7 had pain, all vomited, in only 2 was a mass felt and all but 1 had rectal bleeding. The duration of these signs and symptoms was longer than 36 hr with most ill for 3 or 4 days. All seven infants had abdominal x-rays that showed complete small bowel obstruction. Once the intussusception was suspected, barium enema reduction was attempted without excessive hydrostatic pressure and not for a prolonged time; all the ileocolic intussusceptions were met in the transverse colon with only a minimal reduction produced. It was at this time that a perforation was suddenly noted. All infants required immediate right hemicolectomy for the area (s) of colonic necrosis. Postoperatively, there were two wound infections, a volvulus which left the child with a short gut and another infant suffered severe brain damage. These babies seem to fit a pattern in which they are younger and sicker longer than the average infant with an intussusception, and have a complete small bowel obstruction. These facts may be a warning that such infants are at increased risk for a barium enema bowel perforation.
mesh_terms: D001466:Barium Sulfate / Q000627:therapeutic use; D003106:Colon / Q000293:injuries*; D004733:Enema / Q000009:adverse effects*; D006801:Humans; D007077:Ileal Diseases / Q000628:therapy*; D007223:Infant; D007416:Intestinal Perforation / Q000209:etiology*; D007443:Intussusception / Q000628:therapy*; D008297:Male; D012306:Risk
chemical_list: D001466:Barium Sulfate