title: Malignant epithelial tumors of the anal canal.
abstract: A simplified staging for malignant epithelial tumors of the anal canal is presented. The pattern of recurrence in males is pelvic and perineum, in females pelvis and posterior vaginal wall. Concomitant posterior vaginectomy is advocated. The disease is more common in females than males (4:1). There is little difference between histologic types, i.e. cloacagenic or squamous cell type. Recurrence and survival depend upon depth of invasion and extent of spread rather than histologic cell type. The tumors respond to well-designed surgery, radiotherapy and probably chemotherapy.
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality*; D000328:Adult; D000368:Aged; D001005:Anus Neoplasms / Q000401:mortality*; D002294:Carcinoma, Squamous Cell / Q000401:mortality*; D002295:Carcinoma, Transitional Cell / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies