The effect of imipramine and mianserin on the behavior and EEG afterdischarges induced by single electric stimulation of the rabbit amygdala.
The effect of imipramine (10mg/kg) and mianserin (5 or 10mg/kg) on EEG epileptiform discharges, induced by a single amygdala stimulation in rabbits was studied. Imipramine reduced the duration of EEG afterdischarges, while mianserin prolonged it in leads from both amygdala complexes and from the motor cortex.
D000679:Amygdala / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D003984:Dibenzazepines / Q000494:pharmacology*; D004558:Electric Stimulation; D004569:Electroencephalography; D007099:Imipramine / Q000494:pharmacology*; D008297:Male; D008803:Mianserin / Q000494:pharmacology*; D011817:Rabbits
D003984:Dibenzazepines; D008803:Mianserin; D007099:Imipramine