[Sensitivity to chemotherapeutic preparations of microflora isolated in chronic posttraumatic osteomyelitis].
Chronic post-traumatic osteomyelitis was mainly caused (59.3 per cent) by various gramnegative bacteria. Staphylococcus, Proteus and P. aeruginosa was most frequent. Bacteria were most frequently isolated from associations of 2-5 species and not from monocultures. However, when the patient microflora was studied in dynamics, the whole associations could not be detected in every of the cases. Sensitivity of the causative agents to 23 antibacterial drugs was tested and it was found that the majority of the organisms were sensitive to gentamicin, rifampicin, biseptol, hydroxyquinolines (5-NOK, enteroseptol), furazolidon (except P. aeruginosa). P. aeruginosa was in addition sensitive to polymyxin. Proteus and other enterobacteria were sensitive to nevigramon, staphylococci and other grampositive bacteria were sensitive to oxacillin, lincomycin, novobiocin and fusidin.
D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D002908:Chronic Disease; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D010019:Osteomyelitis / Q000382:microbiology*
Chuvstvitel'nost' k khimioterapevticheskim preparatam mikroflory, vydeliaemoĭ u bol'nykh khronicheskim posttavmaticheskim osteomielitom.