A poly(HEMA) sponge for restoration of articular cartilage defects.
The properties of poly(HEMA) sponges have been studied after implantation in the weight-bearing articular surfaces of young and adult rabbit knees. Only sponges with small pores (less than 50 micrometer) were able to withstand weight-bearing. After 12 weeks, the implants were overgrown by cartilaginous or fibrocartilaginous tissue, and the ingrowth of chondroid tissue into the sponges was observed.
D000818:Animals; D001672:Biocompatible Materials; D002357:Cartilage Diseases / Q000601:surgery; D002358:Cartilage, Articular / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery; D011102:Polyhydroxyethyl Methacrylate / Q000627:therapeutic use*; D011109:Polymethacrylic Acids / Q000627:therapeutic use*; D019736:Prostheses and Implants; D011817:Rabbits
D001672:Biocompatible Materials; D011109:Polymethacrylic Acids; D011102:Polyhydroxyethyl Methacrylate