title: Effect of gelatin infusion on urinary excretion of water and electrolytes in rats.
abstract: The effect of gelatin infusion on water and electrolyte excretion in urine was studied by measuring the volume of excreted urine and the urinary excretion of Na+, K+, Ca++ and Mg++ in a group of male rats before and after receiving infusions of a 5% autoclaved gelatin solution containing 1% glycine (1 ml/100 g body). A similar group of rats received the diluent only (control group). The results obtained showed that the diluent had a diuretic and natriuretic effect but with a less marked degree than gelatin solution which caused marked diuresis, natriuresis and increased excretion of Ca++ and Mg++ in the urine. The K+ excretion was significantly decreased following gelatin infusion. All of these measurements returned to the base-line level after 72 h following gelatin infusion.
mesh_terms: D000818:Animals; D001834:Body Water / Q000378:metabolism*; D002118:Calcium / Q000652:urine; D004573:Electrolytes / Q000652:urine*; D005780:Gelatin / Q000494:pharmacology*; D007700:Kinetics; D008274:Magnesium / Q000652:urine; D008297:Male; D011188:Potassium / Q000652:urine; D051381:Rats; D012964:Sodium / Q000652:urine
chemical_list: D004573:Electrolytes; D005780:Gelatin; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium