title: [Symptomatic treatment of ichtyosarcotoxic disease by associated dexamethasone, cobalamine and tiapride (author's transl)].
abstract: Ciguatera is an ichtyosarcotoxic disease observed in South Pacific after consuming some species of fish. Common symptoms in benign forms are: asthenia, itching, subjective troubles of sensibility and digestive disorders. Rarer acute form lasts 2/6 days and then symptoms recede slowly. Symptoms might be reproduced if the same toxic fish is eaten again. A dinoflagellate seems responsible for this disease which has no specific treatment. The authors have added tiapride to dexamethasone and cobalamine, already used as symptomatic treatment. They report their experience and think that tiapride brought a noticeable improvement to the neurologic disorders.
mesh_terms: D000818:Animals; D001549:Benzamides / Q000008:administration & dosage*; D036841:Ciguatera Poisoning; D003907:Dexamethasone / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005400:Fishes, Poisonous; D006801:Humans; D008387:Marine Toxins / Q000506:poisoning*; D013976:Tiapamil Hydrochloride / Q000008:administration & dosage*; D014805:Vitamin B 12 / Q000008:administration & dosage*
chemical_list: D001549:Benzamides; D008387:Marine Toxins; D003907:Dexamethasone; D014805:Vitamin B 12; D013976:Tiapamil Hydrochloride
vernacular_title: Traitement symptomatique de l'ichtyosarcotoxisme par l'association dexaméthasone, cobalamine et tiapride.