Covalent binding of methotrexate to immunoglobulins and the effect of antibody-linked drug on tumor growth in vivo.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000008:administration & dosage; D004952:Esters / Q000138:chemical synthesis; D007074:Immunoglobulin G / Q000378:metabolism; D007136:Immunoglobulins / Q000276:immunology / Q000378:metabolism*; D008223:Lymphoma / Q000188:drug therapy / Q000276:immunology; D008727:Methotrexate / Q000378:metabolism* / Q000627:therapeutic use; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy; D011379:Prognosis; D011485:Protein Binding; D011786:Quality Control; D013678:Technology, Pharmaceutical
D000912:Antibodies, Neoplasm; D004952:Esters; D007074:Immunoglobulin G; D007136:Immunoglobulins; D008727:Methotrexate