Determinants of ventricular refractory periods in children with congenital heart disease: effects of cycle length and age.
Ventricular effective refractory periods (ERP) and functional refractory periods (FRP) were determined by programmed ventricular extrastimulation in 53 pediatric patients with a spectrum of congenital heart disorders. Of these 63 children (ages 8 months to 18 years), 38 were preoperative, 17 had repair of their cardiac lesion via right ventriculotomy, and eight were postoperative without a ventriculotomy. We demonstrated that there was a linear relationship between the cycle length and ventricular refractory periods. The regression equations 73 + 0.29 x cycle length (msec) for the ventricular ERP (msec) and 80 + 0.30 x cycle length (msec) for ventricular FRP (msec) were found to define the determined properties of ventricular refractory periods (VRP) in children. These VRP characteristics were independent of age in children less than 13 years of age.
D000200:Action Potentials; D000293:Adolescent; D000375:Aging; D006328:Cardiac Catheterization; D002648:Child; D004594:Electrophysiology; D006330:Heart Defects, Congenital / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D007223:Infant