Changes in systemic arterial pressure during sleep in Shy-Drager syndrome.
Polygraphic findings during spontaneous nocturnal sleep of 2 patients suffering from Shy-Drager syndrome are reported. In both patients, total sleep time was reduced--sleep latency and awakening periods during the night being increased. Considerable reductions of rapid eye movement (REM) stage and, in 1 patient, also of deep non-REM (NREM; stages 3-4) were found. No apneas were recorded. In normal subjects, systemic systolic and diastolic pressure decreases during all the sleep stages; in our patients, arterial pressure values rose progressively during NREM sleep stages and showed a further increase in REM sleep. In all the sleep stages, sudden phasic swings of systemic arterial pressure were observed.
D000368:Aged; D001284:Atrophy; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis*; D001794:Blood Pressure; D001933:Brain Stem / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D004569:Electroencephalography; D004576:Electromyography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009410:Nerve Degeneration; D012791:Shy-Drager Syndrome / Q000175:diagnosis* / Q000473:pathology; D012894:Sleep Stages