[Quantitative criteria of radiation pathomorphosis in focal irradiation of rectal cancer].
One study group consisting of 22 patients received 4-5 focal doses of 6 Gy every other day (total dose--24-30 Gy, 1,400-1,600 NSD). There was a 15-20 day interval between radiation therapy commencement and surgery. Another 12 patients received 4 daily doses of 5 Gy (total dose--20 Gy, 1,140 NSD) and were operated on 24-48 hrs after irradiation. The oncolytic index was 36% plus or minus 4.8 in study group 1 and 21% plus or minus 4.4--in group 2 (P less than 0.05). Mitotic index in group 1 fell from 6.7 to 3.1%, while in group 2--to zero.
D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008940:Mitotic Index / Q000528:radiation effects; D011300:Preoperative Care; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D012007:Rectum / Q000473:pathology; D013997:Time Factors
O kolichestvennykh kriteriiakh luchevogo patomorfoza pri kontsentrirovannom obluchenii raka priamoĭ kishki.