Photochemotherapy in psoriasis and other skin diseases.
Oral psoralen-ultraviolet A (PUVA) therapy is one of the most effective treatment methods available for psoriasis. The combination of psoralen and ultraviolet A radiation inhibits DNA synthesis. Its usefulness in treating other skin conditions such as mycosis fungoides and vitiligo is being explored. While PUVA seems relatively safe, long-term risks associated with this therapy are unclear. Special training and careful dosimetry are important.
D006801:Humans; D009182:Mycosis Fungoides / Q000188:drug therapy*; D011701:PUVA Therapy / Q000009:adverse effects; D010778:Photochemotherapy; D011565:Psoriasis / Q000188:drug therapy*; D012306:Risk; D013997:Time Factors; D014820:Vitiligo / Q000188:drug therapy*