Development of a model for integrated pharmacokinetic and pharmacodynamic studies of intravenous anaesthetic agents: applications to minaxolone.
D000328:Adult; D000777:Anesthetics / Q000378:metabolism / Q000494:pharmacology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007263:Infusions, Parenteral; D007700:Kinetics; D008297:Male; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D011278:Pregnanes / Q000494:pharmacology*; D011280:Pregnanolone / Q000009:adverse effects / Q000031:analogs & derivatives / Q000097:blood / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects
D000777:Anesthetics; D011278:Pregnanes; C020413:minaxolone; D011280:Pregnanolone