Prevention of the hepatotoxic action of N-hydroxy-2-acetylaminofluorene in the rat by inhibition of N-O-sulfation by pentachlorophenol.
D015073:2-Acetylaminofluorene / Q000031:analogs & derivatives*; D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology / Q000517:prevention & control*; D002733:Chlorophenols / Q000494:pharmacology*; D005260:Female; D006881:Hydroxyacetylaminofluorene / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000633:toxicity*; D008099:Liver / Q000473:pathology; D010416:Pentachlorophenol / Q000494:pharmacology*; D051381:Rats; D013431:Sulfates / Q000378:metabolism
D002733:Chlorophenols; D013431:Sulfates; D006881:Hydroxyacetylaminofluorene; D015073:2-Acetylaminofluorene; D010416:Pentachlorophenol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase