Serum levels of myoglobin and creatine kinase in Duchenne muscular dystrophy.
Using a sensitive myoglobin-radioimmunoassay (Mb-RIA) serum Mb was measured in 50 patients with Duchenne muscular dystrophy (DMD) and compared with the serum creatine kinase (CK) activities. The Mb concentrations (normal range 4-60 ng/ml) measured ranged between 160-6,000 ng/ml and did not only show a significant correlation to the CK but also an inverse relationship to the age of the patients. It is suggested that Mb is an essential adjunct in the diagnosis of DMD.
D000293:Adolescent; D000375:Aging; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D009136:Muscular Dystrophies / Q000097:blood*; D009211:Myoglobin / Q000097:blood*; D011863:Radioimmunoassay
D009211:Myoglobin; D003402:Creatine Kinase