The lack of toxicity of intravitreally administered triamcinolone acetonide.
We gave one eye of each 21 rabbits an intravitreal injection of 1 mg of triamcinolone acetonide; the other eye received an injection of an equal volume of saline solution as a control. Results of slit-lamp examinations, ophthalmoscopy, intraocular pressure, electroretinography, and light electron microscopy all remained normal throughout the three-month course of the experiment, demonstrating the lack of ocular toxicity of triamcinolone acetonide in the rabbit.
D000818:Animals; D004596:Electroretinography; D005451:Fluorescein Angiography; D007429:Intraocular Pressure / Q000187:drug effects; D009887:Ophthalmoscopy; D011817:Rabbits; D014222:Triamcinolone Acetonide / Q000633:toxicity*; D014822:Vitreous Body / Q000187:drug effects*
D014222:Triamcinolone Acetonide