title: The Sweet syndrome in children.
abstract: Two children are described with the Sweet syndrome (acute febrile neutrophilic dermatosis), a rare skin disorder usually seen in middle-aged women. Typical features include spiking fever, neutrophilic leukocytosis, raised painful erythematous plaques and nodules reflecting a cutaneous dermal infiltrate composed of polymorphonuclear leukocytes and rapid resolution in response to systemically administered corticosteroid. The eruption is believed to represent a hypersensitivity reaction to antecedent infection or concurrent malignancy.
mesh_terms: D002648:Child; D002675:Child, Preschool; D003872:Dermatitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D000078404:Epidermal Cells; D004817:Epidermis / Q000473:pathology; D005148:Facial Dermatoses / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005334:Fever / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007223:Infant; D007964:Leukocytosis / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D010267:Parapsoriasis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D011241:Prednisone