Comparative in vivo kinetics of some new 99mTc-labelled acetanilido iminodiacetates.
The in vivo kinetics of five new 99mTc-labelled acetanilido iminodiacetates, analogous to 99mTc-p-butyl IDA, were studied in experimental animals by means of their distribution in mice and scintigrams of rabbits. The new compounds were specifically eliminated via the hepatobiliary system with various rates of hepatic extraction. Urinary excretion of the complexes was minimal.
D000818:Animals; D005704:Gallbladder / Q000000981:diagnostic imaging*; D007098:Imino Acids / Q000378:metabolism / Q000633:toxicity; D008099:Liver / Q000000981:diagnostic imaging*; D008297:Male; D051379:Mice; D015609:Organotechnetium Compounds; D011817:Rabbits; D011877:Radionuclide Imaging; D013667:Technetium / Q000378:metabolism / Q000633:toxicity; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid
D007098:Imino Acids; D015609:Organotechnetium Compounds; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; C030758:technetium Tc 99m (meta-butoxy)iminodiacetic acid; C030757:technetium Tc 99m (ortho-butyl)iminodiacetic acid; C030759:technetium Tc 99m (ortho-hexyloxy)iminodiacetic acid; C024340:technetium Tc 99m (para-butyl)iminodiacetic acid; C030760:technetium Tc 99m (para-hexyloxy)iminodiacetic acid; C030761:technetium Tc 99m (para-tert-butyl)iminodiacetic acid; D013667:Technetium