Sensitivity of chromatin to heparin in chromic atrophic gastritis in carcinoma free and carcinoma bearing stomach as revealed by flow cytometry.
Heparin, a natural polyanion, was applied to human gastric mucosal cells in chronic atrophic gastritis originating from the carcinoma free and the carcinoma bearing stomach. Both groups showed a different sensitivity to heparin expressed as different accessibility of the chromatin to the fluorochrone, as revealed by flow cytometry.
D001706:Biopsy; D002843:Chromatin / Q000187:drug effects*; D004247:DNA / Q000032:analysis; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005756:Gastritis / Q000188:drug therapy*; D005757:Gastritis, Atrophic / Q000188:drug therapy* / Q000473:pathology; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology
D002843:Chromatin; D006493:Heparin; D004247:DNA