The blood volume and splenic red cell pool in hairy cell leukemia.
Investigating the splenic red cell pool in 7 patients with hairy cell leukemia we have found unusually high values of retained erythrocytes (means 527 ml, SD 264) with a range from 300 to 998 ml. This amount represents on average 26% of the total red cell mass. The blood volume in these patients ws 26% greater than predicted by NADLER et al. Following splenectomy, the hemoglobin improved with 49.3% (SD 29.1).
D000328:Adult; D004911:Erythrocyte Volume; D005260:Female; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000097:blood* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013154:Spleen / Q000503:physiopathology*; D013156:Splenectomy