[Changes in superoxide dismutase and glutathione peroxidase activities during the process of intensification of lipid peroxidation in hepatic ischemia].
A study was made of changes in the activity of superoxide dismutase and glutathione peroxidase, in the level of the antioxidant activity and lipid peroxides during development of liver ischemia. It was shown that the intensification of peroxidation in ischemia is determined by the impairment of the systems maintaining the constant low level of peroxide reactions in an intact cells. The level of antioxidants, glutathione peroxidase and superoxide dismutase drastically falls in liver ischemia.
D000818:Animals; D005979:Glutathione Peroxidase / Q000378:metabolism*; D007511:Ischemia / Q000201:enzymology*; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008099:Liver / Q000098:blood supply* / Q000201:enzymology / Q000378:metabolism; D010084:Oxidation-Reduction; D010544:Peroxidases / Q000378:metabolism*; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*
D008054:Lipid Peroxides; D010544:Peroxidases; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
Izmenenie aktivnosti superoksiddismutazy i glutationperoksidazy v protsesse intensifikatsii perekisnogo okisleniia lipidov pri ishemii pecheni.