[Direct and induced lymphocytotoxicity to rabbit hepatocytes in chronic active hepatitis].
The lymphocytotoxicity to rabbit hepatocytes either direct or serum induced was evaluated in chronic active hepatitis (CAH). We obtained the following results: a) the direct lymphocytotoxicity obtained in CAH patients significantly correlated with the cytotoxicity induced by CAH sera in normal lymphocytes; b) no difference could be recorded in CAH HBsAG positive or negative; c) the target antigen of the immune reaction seems to be the liver specific lipoprotein.
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology; D002353:Carrier State; D002908:Chronic Disease; D003602:Cytotoxicity, Immunologic; D006505:Hepatitis / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D008099:Liver / Q000276:immunology*; D011817:Rabbits
D000961:Antilymphocyte Serum; D006514:Hepatitis B Surface Antigens
La linfocitotossicità diretta ed indotta verso epatociti di coniglio nell'epatite cronica attiva.