[State of the nonspecific protection factors of the body in chronic parotitis treated with penicillin].
The factors of host nonspecific protection (FHNP) in patients with chronic parotiditis treated and not treated with penicillin were studied. 81 patients with chronic parotiditis and 25 healthy persons were examined for comparison of the values of FHNP. 38 patients with chronic parotiditis in the phase of exacerbation were treated with penicillin in doses of 500000 units 4 times a day for 7 days. The following FHNP were determined 7 days after the exacerbation start: bactericidal activity of blood serum, lysozyme activity of saliva and blood, phagocytosis, immune adhesion test, complement. The investigation showed a significant decrease in FHNP in the patients with chronic parotiditis in the phase of exacerbation (P less than 0.01, less than 0.05). The treatment with penicillin resulted in a further decrease in the levels of FHNP which suggests inclusion of stimulating therapy into the combined treatment of patients with chronic parotiditis.
D000328:Adult; D002648:Child; D002908:Chronic Disease; D003864:Depression, Chemical; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects*; D010309:Parotitis / Q000188:drug therapy / Q000276:immunology*; D010406:Penicillins / Q000276:immunology*
D010406:Penicillins
Sostoianie faktorov nespetsificheskoĭ zashchity organizma u bol'nykh khronicheskim parotitom pri lechenii penitsillinom.