title: Immunoglobulin and complement receptor-bearing cells in cultures of mouse decidual tissue.
abstract: Cells disaggregated from decidual tissue of the pregnant mouse were cultured overnight and examined in erythrocyte-antibody rosetting assays for the presence of cell surface receptors for the Fc region of immunoglobulin. Fc receptor-bearing cells were present from Day 4 post coitum (Day 1 = day of mating) as an increasing proportion of the total number of cells in the cultures, although the precise proportion showed considerable strain-dependent variation. In a similar assay, complement receptor-bearing cells were not detected in cultures of decidual tissue until 14-15 days of pregnancy. The presence of Fc receptor-bearing cells in the decidua supports the suggestion that this tissue may have a role in the immunological interactions between the mother and her antigenically alien embryo.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D003656:Decidua / Q000166:cytology / Q000276:immunology*; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains; D011247:Pregnancy; D011951:Receptors, Complement / Q000032:analysis; D011961:Receptors, Fc / Q000032:analysis*; D012397:Rosette Formation
chemical_list: D011951:Receptors, Complement; D011961:Receptors, Fc