Preliminary studies on experimentally induced calcification of femoral arteries in the rat.
Ligatured segments of femoral artery were incubated in vivo and examined after 15 days. Microscopic observation of these arterial segments showed medial calcification. Initial deposition of calcium occurs in the internal elastic lamina. Invasion of the tunica media occurs along the deep elastic fibres and in the fibrillar substances.
D000818:Animals; D002114:Calcinosis / Q000209:etiology / Q000473:pathology*; D005263:Femoral Artery / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D051381:Rats