Gentamicin-polymethyl-methacrylate beads in the treatment of chronic bone sepsis.
Eighteen cases of chronic bone infection were treated by implantation of gentamicin-polymethyl-methacrylate beads together with surgery. Healing by primary or secondary intention occurred in 14 cases, and the method is considered effective, safe and convenient.
D001424:Bacterial Infections / Q000188:drug therapy*; D001826:Body Fluids / Q000032:analysis; D001847:Bone Diseases / Q000188:drug therapy* / Q000382:microbiology; D002908:Chronic Disease; D004343:Drug Implants; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008768:Methylmethacrylates / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D014945:Wound Healing / Q000187:drug effects
D004343:Drug Implants; D005839:Gentamicins; D008768:Methylmethacrylates; C030159:gentamicin-polymethylmethacrylate bead