Effects of mitogenic stimulation on the exchangeable pool of calcium in 3T3-cells.
The exchange of calcium between cells and external medium was studied in quiescent and mitogenic stimulated sparse 3T3-cells. It was found that mitogenic stimulation caused a rapid reduction of the size of a calcium containing compartment that is exchangeable with the culture medium. Furthermore the mitogenic stimuli caused a translocation of calcium from this exchangeable compartment to a much less exchangeable compartment that is possibly located intracellularly.
D000818:Animals; D001769:Blood; D002118:Calcium / Q000378:metabolism*; D002460:Cell Line; D003470:Culture Media; D005260:Female; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D008934:Mitogens / Q000494:pharmacology*; D011247:Pregnancy
D003470:Culture Media; D008934:Mitogens; D002118:Calcium