[Topographic aspects of the progression of diabetic retinopathy (an experimental set-up for the evaluation of medical influencability) (author's transl)].
Within the past five years fluorescein angiography of six different fundus areas was performed at intervals of six months on a total of 365 patients exhibiting non-proliferative diabetic retinopathy without diabetic maculopathy. Within that period, diabetic maculopathy was observed to develop in 195 eyes, vasoproliferation in 20 eyes. Within the general scope of fluctuation of the angiographic picture of retinal capillary perfusion disturbance, zones of continuous progression were encountered in 246 eyes. In 183 out of 195 eyes which developed diabetic maculopathy the distinct areas of relentless progression were located 2--6 PD's temporal to the macula; in the total 20 eyes which had advanced to the proliferative stage similar areas were encountered, located nasally 2--6 PD's above and below the optic disk.
D002199:Capillary Permeability; D003930:Diabetic Retinopathy / Q000188:drug therapy / Q000473:pathology*; D005451:Fluorescein Angiography; D006801:Humans; D007511:Ischemia / Q000473:pathology; D008266:Macula Lutea / Q000473:pathology; D012160:Retina / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology
Topographische Aspekte der Progredienz der diabetischen Retinopathie. Versuchsanordnung zur Beurteilung medikamentöser Beeinflussbarkeit.