Histopathology reporting in large bowel cancer.
A review of histopathology reports on 2046 patients in the large bowel cancer project showed considerable observer variation in histological grading. Dukes staging, and lymph node harvest. These parameters have a well-established relationship to prognosis, but, if they are to be applied for both clinical and research purposes, they must be assessed consistently. A minimal level of information which should be recorded from a resection specimen is suggested, with a description of the methods by which this information can be obtained.
D000230:Adenocarcinoma / Q000473:pathology; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology*; D007420:Intestine, Large; D008207:Lymphatic Metastasis; D008722:Methods; D009367:Neoplasm Staging / Q000379:methods; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology; D013048:Specimen Handling