title: Genetic variation in Cumbrians.
abstract: Regional variation in the genetic constitution of the Cumbrian population is demonstrated in a survey of blood groups, red cell enzymes, and secretor status in a large sample of schoolchildren. In particular, the south and centre appear to be distinct from the remainder of Cumbria, but in different directions. The features of the central Lake District, tending towards gene frequencies observed in Norway, suggest that it may be a region in which the presence of a relict population is still detectable.
mesh_terms: D000293:Adolescent; D001789:Blood Group Antigens / Q000235:genetics*; D002648:Child; D004739:England; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D007070:Immunoglobulin A / Q000235:genetics*; D007071:Immunoglobulin A, Secretory / Q000235:genetics*; D008297:Male; D010641:Phenotype; D012463:Saliva / Q000276:immunology; D044465:White People
chemical_list: D001789:Blood Group Antigens; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory