Effects of corticospinal lesions upon treadmill locomotion by cats.
We studied the pattern of stepping in cats, before and after the placement of lesions in the corticospinal system. We found a deficit after the lesions, which was characterized by increased extension of the involved hindlimbs during the stance (E2--E3) phase of the step cycle. This deficit lasted two weeks or less. It may reflect loss of inhibitory influences upon extensor motoneuron pools.
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000502:physiology*; D006614:Hindlimb / Q000294:innervation; D007596:Joints / Q000294:innervation; D008124:Locomotion; D009044:Motor Cortex / Q000502:physiology; D011434:Proprioception; D011712:Pyramidal Tracts / Q000502:physiology; D013003:Somatosensory Cortex / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*