title: Whole body surface loss of trace metals in normal males.
abstract: Whole body surface losses of zinc, copper, and iron were measured in 13 male volunteers who lived in a controlled environment for 4 to 9 months. For 88 daily samples, the mean losses for zinc, copper, and iron were 0.50, 0.34, and 0.33 mg/day (3.9, 26, and 2.1% of the mean dietary intakes, respectively). There was a large variance in metal losses with no significant differences in variance within-versus-between subjects or on the same-versus-different diets. The surface losses of zinc and iron increased the apparent dietary requirements determined by balance measurements only 5 and 3%, respectively, while the increase in copper requirement due to surface loss was 25 to 30%.
mesh_terms: D000328:Adult; D001830:Body Surface Area; D003300:Copper / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009751:Nutritional Requirements; D013048:Specimen Handling / Q000379:methods; D013542:Sweat / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism*
chemical_list: D003300:Copper; D007501:Iron; D015032:Zinc