title: The composition of tuberous sclerosis grey matter.
abstract: The chemical analysis of grey matter from a tuberous sclerosis subject indicated the presence of two different types of grey matter based on two distinctly different ganglioside concentrations. Both samples had gangliosides of reduced concentration with an abnormal composition compared to normal grey matter as evidenced from their thin-layer chromatography profiles. Analyses of the glycoprotein fraction from both samples revealed increased glycoprotein content, particularly in total carbohydrate. This observation was consistent with previous studies of angiofibromas and angiomyolipomas.
mesh_terms: D001921:Brain / Q000473:pathology; D001923:Brain Chemistry; D005732:Gangliosides / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis*; D006801:Humans; D007223:Infant; D008055:Lipids / Q000032:analysis*; D008297:Male; D014402:Tuberous Sclerosis / Q000378:metabolism* / Q000473:pathology
chemical_list: D005732:Gangliosides; D006023:Glycoproteins; D008055:Lipids