[Electrophysiologic and neurochemical characteristics of cultured cortical neuroblasts from newborn rats].
The neuroblasts of the newborn rat cortex continued to be differentiated in cultured tissue judging by growth of the MP, the possibility of its recording during a longer time (10--15 min) and the transmitter sensitivity. At a certain stage of the differentiation the heterogeneity of the morphologically uniform neuroblasts is manifested by the obvious difference between MP values and patterns, by the presence of neuroblasts with stable and fluctuating MPs, and by the variety of responses to application of ACh and GABA. The neuroblasts at a rather early stage of their development revealed absence of AP, lesser MPs, reduced sensitivity to ions, no transmitter sensitivity.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D000831:Animals, Newborn; D002454:Cell Differentiation; D002465:Cell Movement; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology* / Q000187:drug effects; D008564:Membrane Potentials / Q000187:drug effects; D011188:Potassium / Q000494:pharmacology; D051381:Rats; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D005680:gamma-Aminobutyric Acid; D000109:Acetylcholine; D011188:Potassium
Elektrofiziologicheskie i neĭrokhimicheskie kharakteristiki neĭroblastov kory golovnogo mozga novorozhdennykh krys v usloviiakh kul'tivirovaniia.