[Microtubule-independent cell surface stabilization in normal and transformed connective tissue cells].
Effects of colcemid on the distribution of pseudopodial activity in both normal and transformed connective tissue cells was studied by means of phase contrast microscopy and time-lapse cinematography. It was shown that normal as well as transformed fibroblasts are able to stabilize their surface independently on the presence of colcemid, however, in transformed cells this ability is more expressed. Possible mechanisms of this stabilization of cellular surface, independent on microtubules is discussed.
D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology*; D002478:Cells, Cultured; D003078:Colchicine / Q000494:pharmacology*; D005347:Fibroblasts / Q000187:drug effects*; D007739:L Cells / Q000187:drug effects*; D051379:Mice; D008809:Mice, Inbred C3H; D008870:Microtubules / Q000502:physiology
D003078:Colchicine
Nezavisimaia a ot mikrotrubochek stabilizatsiia kletochnoĭ poverkhnosti u normal'nykh i transformirovannykh soedinitel'notkannykh kletok.