The construction, surgical implantation, and use of gastric catheters and a pyloric cuff.
Surgically implantable gastric catheters and a pyloric cuff have been developed for the rat for experimentation on the regulation of food intake. The implants are suitable for chronic or acute use. The catheters allow for the infusion of solutions directly into the lumen of the stomach as well as for the evacuation or sampling of contents. Intraluminal pressure and motility may also be monitored through the catheters. The pyloric cuff permits the experimental occlusion of the pylorus for selected periods of time. These devices are of importance when elucidating the peripheral and central regulation of food intake in the rat.
D000818:Animals; D001362:Avoidance Learning; D002408:Catheters, Indwelling / Q000009:adverse effects / Q000295:instrumentation*; D005247:Feeding Behavior; D051381:Rats; D013270:Stomach; D013530:Surgical Wound Infection / Q000209:etiology; D013649:Taste