Preservation of neutrophils in CPD-adenine.
Human neutrophils were stored in vitro in CPD or CPD-adenine plasma under conditions designed to simulate those of leukapheresis followed by short-term preservation. Viability, morphology by light microscopy, and phagocytic ability of cells stored in either anticoagulant were similar when studied sequentially during 72 hours of storage. Thus, CPD-adenine offered no advantage, under the conditions employed, over standard CPD without adenine.
D000225:Adenine / Q000494:pharmacology*; D001793:Blood Preservation; D002951:Citrates / Q000494:pharmacology*; D004905:Erythrocyte Aging; D005947:Glucose; D005958:Glucosephosphates / Q000494:pharmacology*; D006801:Humans; D009504:Neutrophils / Q000166:cytology; D010587:Phagocytosis
D002951:Citrates; D005958:Glucosephosphates; C007077:citrate phosphate dextrose; D005947:Glucose; D000225:Adenine