Sickle-delta beta thalassemia: mild sickling disorder with serious morbidity in pregnancy.
Two patients with sickle-delta gamma thalassemia are reported who experienced the typical complications of sickling disorders in the last 2 months of 4 pregnancies. The diagnosis, genetics, and management of pregnancy in this rare hematologic disease, which causes minimal morbidity in the nonpregnant woman, are discussed.
D000208:Acute Disease; D000328:Adult; D000755:Anemia, Sickle Cell / Q000175:diagnosis*; D005260:Female; D006451:Hemoglobin, Sickle / Q000032:analysis / Q000235:genetics; D006801:Humans; D008297:Male; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000235:genetics; D013789:Thalassemia / Q000175:diagnosis*
D006451:Hemoglobin, Sickle