[Electroosmotic superstability in living cells. Unified model of the morphologically active membrane cell-unit with electrogenic K+, Na+-transport].
A mathematical model of electroosmotic homeostasis in mammalian cells is developed. The need for the transmembrane ionic heterogeneity follows the requirement of the system's stability under varying conditions. The quantitative stability criterion is proposed, useful for estimating the physiological state of cells in experiment. The membrane growth in the case of stable cell-units promotes the development of surface invaginations into the internal volume. An invasive metastatic growth suggests the loss of stability.
D001693:Biological Transport, Active; D002462:Cell Membrane / Q000378:metabolism; D008433:Mathematics; D008954:Models, Biological; D009994:Osmolar Concentration; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D012964:Sodium; D011188:Potassium
K analizu elektroosmoticheskoĭ usto=56ichivosti v zhivotnykh kletkakh. Unifitsirovannaia model' morfoligicheski aktivnoĭ membrannoĭ oblockhi s electrogennym K+, Na+-transportem.