[Cytochrome P450 inactivation on a cathode].
It was concluded on the grounds of spectrophotometric analysis of cytochrome P450 electrolysis products that cytochrome P450 unlike other hem-containing proteins is not reduced on the cathode. At the potential -1.5V it is reduced simultaneously with the transformation into cytochrome P420. Inactivation in the electric field on the electrode surface is irreversible. When the potential is above -1.4V no inactivation of cytochrome P450 takes place.
D055598:Chemical Phenomena; D002621:Chemistry; D003577:Cytochrome P-450 Enzyme System; D003580:Cytochromes; D004572:Electrolysis; D006900:Hydroxylation; D007700:Kinetics
D003580:Cytochromes; C013464:cytochrome P420; D003577:Cytochrome P-450 Enzyme System
Inaktivatsiia tsitokhroma P450 na katode.