Auditory intensity discrimination after selective loss of cochlear outer hair cells.
The contributions of the inner and outer hair cells of the mammalian cochlea to auditory intensity discrimination were evaluated in a combined behavioral-anatomical study of the guinea pig. Intensity difference thresholds were unchanged from baseline values after selective destruction of outer hair cells, suggesting that those cells are unnecessary for normal intensity discrimination.
D000161:Acoustic Stimulation; D000818:Animals; D001309:Auditory Threshold / Q000187:drug effects; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000502:physiology*; D006199:Hair Cells, Auditory, Inner / Q000187:drug effects / Q000502:physiology; D006309:Hearing / Q000187:drug effects; D007612:Kanamycin / Q000494:pharmacology; D008297:Male
D007612:Kanamycin