[Characteristics of the electrophysical parameters of the growing mycelium of Act. nodosus, a producer of amphotericin B].
The dielectric constants E1 and impedance Z of the growing mycelium of Act. nodosus producing amphotericin B were determined with the method of dielectric estimations at 10(3)-10(8), the concentrations of the biomass and antibiotic being determined simultaneously. It was found that the values of the dielectric permeability and impedance may be indicative of the biomass volume and antibiotic accumulation respectively. It is suggested that standard curves be plotted and the electrophysic parameters be used for automatic and continuous control of the Act. nodosus growth. Calculation of the viability coefficient according to B. N. Tarusov showed that it directly correlated with the economic coefficient. It is concluded that additional information on the medium such as the dipole moment, Z-potential and others, may be obtained using the electrophysic parameters.
D000666:Amphotericin B / Q000096:biosynthesis*; D055592:Biophysical Phenomena; D001703:Biophysics; D004553:Electric Conductivity; D008433:Mathematics; D013302:Streptomyces / Q000502:physiology*
D000666:Amphotericin B
Osobennosti élektrofizicheskikh parametrov rastushchego mitseliia Act. nodosus--produtsent amfoteritsina B.