Complete remission of idiopathic pure red cell aplasia. Case reports.
Two patients with pure red cell aplasia of undetermined aetiology are in sustained, complete remission after immunosuppressive therapy. In the first, short-term supplementary plasmapheresis was used during initial chemotherapy, and in the second, anabolic androgens were administered. In both patients haematopoietic recovery was temporally related to the withdrawal of the cyclophosphamide used to cause immunosuppression in the patients over a 4- and 6-month period respectively.
D000293:Adolescent; D000741:Anemia, Aplastic / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D010110:Oxymetholone / Q000627:therapeutic use; D010956:Plasmapheresis; D011241:Prednisone / Q000627:therapeutic use*; D013997:Time Factors
D003520:Cyclophosphamide; D010110:Oxymetholone; D011241:Prednisone