title: Carcinosarcoma of prostate.
abstract: A case of carcinosarcoma of the prostate is described. Review of the literature revealed few cases, only 2 being well documented. The tumor presented as a urethral polypoid obstruction of the bladder neck and proved to involve bilaterally, the prostate and the seminal vesicles with metastases to the regional lymph nodes. Light microscopic findings are described as a multimorphic tumor with simultaneous presence of sarcoma, characteristically being malignant cartilage, rhabdomyosarcomatous component, and poorly differentiated carcinomatous areas. Controversy of this morphologic entity is discussed briefly. These tumors are highly anaplastic and rapidly fatal.
mesh_terms: D000328:Adult; D002296:Carcinosarcoma / Q000473:pathology*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*