Prostatic cancer with an unusual presentation: polymyositis and mediastinal adenopathy.
A 67-year-old man with prostate cancer presented with acute polymyositis and vocal cord paralysis as a result of mediastinal lymphadenopathy. His clinical course was unusual, with the development of a malignant pleural effusion, supraclavicular adenopathy, and osteolytic bone lesions. Urologic symptoms developed only pre-terminally, and osteoblastic bone metastases were not documented. This case suggests that prostate cancer need not have a simple natural history.
D000230:Adenocarcinoma / Q000150:complications*; D000368:Aged; D001859:Bone Neoplasms / Q000209:etiology / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D009220:Myositis / Q000209:etiology*; D010997:Pleural Neoplasms / Q000556:secondary; D011471:Prostatic Neoplasms / Q000150:complications*; D014826:Vocal Cord Paralysis / Q000209:etiology