Modifications in the aminoether side chain of clomiphene influence affinity for a specific antiestrogen binding site in MCF 7 cells cytosol.
D001667:Binding, Competitive; D001943:Breast Neoplasms / Q000378:metabolism*; D002460:Cell Line; D002996:Clomiphene / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D003600:Cytosol / Q000378:metabolism; D004965:Estrogen Antagonists / Q000378:metabolism*; D005260:Female; D006801:Humans; D007700:Kinetics; D013329:Structure-Activity Relationship; D013629:Tamoxifen / Q000378:metabolism
D004965:Estrogen Antagonists; D013629:Tamoxifen; D002996:Clomiphene