Pig neutrophil adherence in experimentally induced salmonellosis.
In vitro neutrophil adherence was characterized in healthy newly weaned pigs following experimentally induced infection with Salmonella choleraesuis, A typhimurium, and S anatum. The adherence of pig neutrophils to nylon fiber columns was shown to be reproducible on a day-to-day basis. Neutrophil adherence was significantly increased in a group of pigs at 6, 30, and 48 hours after S choleraesuis was inoculated (orally). Neutrophil adherence was not significantly altered in groups of pigs inoculated with S typhimurium and S anatum, although individual pigs did show an apparent increase in adherence after S typhimurium was inoculated. An association between increased neutrophil adherence and acute inflammatory disease was made.
D000818:Animals; D002448:Cell Adhesion; D005260:Female; D008297:Male; D009504:Neutrophils / Q000502:physiology*; D012481:Salmonella Infections, Animal / Q000097:blood*; D013552:Swine; D013553:Swine Diseases / Q000097:blood*