[Treatment of Morbus Menière with intratympanally applied Gentamycin (author's transl)].
Since 1974 we have treated 59 patients suffering from unilateral and bilateral (two patients) Morbus Menière with intratympanal application of gentamycin-sulfate. In contrast to earlier attempts using  this method, we did not try to destroy the vestibular apparatus, but taking into our considerations the recent findings about the pathophysiological mechanism of Morbus Menière, only to damage the secretory epithelium, thus preventing the endolymphatic hydrops. Releave from symptoms could be obtained in more than 90% of our patients.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004432:Ear, Middle; D005839:Gentamicins / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008575:Meniere Disease / Q000188:drug therapy*; D008875:Middle Aged
D005839:Gentamicins
Behandlung des Morbus Menière mit intratympanal appliziertem Gentamycin-Sulfat.