Doxorubicin hypogastric artery infusion combined with hyperthermia therapy for transitional cell carcinoma of the bladder.
Six patients with bulky state C bladder cancer underwent doxorubicin hypogastric artery infusion combined with local bladder hyperthermia as a preoperative adjunct to radical cystectomy. The regimen was well-tolerated. Extensive tumor necrosis on the bladder luminal surface was seen during histopathologic examination.
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D004317:Doxorubicin / Q000008:administration & dosage*; D005260:Female; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*
D004317:Doxorubicin