[Long-term effects of weight reduction on body weight and metabolic parameters in adipose non-diabetics and adipose maturity-onset diabetics].
In 28 adipose patients (15 females, 13 males) with normal carbohydrate tolerance and in 35 adipose maturity-onset-diabetics (27 females, 8 males) a significant reduction of the ideal weight index was achieved by a stationary zero diet. The serum fasting values of triglycerides. cholesterol and uric acid decreased. The clearest influence was found in pathologically increased values. This also concerns the improvement of the glucose tolerance in diabetics, which is expressed in the change of the antidiabetic regime. 48.5 +/- 11.7 months after the cure in the after-examined patients with normal carbohydrate tolerance (n = 27) a slight decrease of the weight, in the group of diabetics (n = 31) a slight increase was observed. Despite these slight, non-significant changes of weight the situation in the carbohydrate, fat and purin metabolism on an average deteriorated.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D003920:Diabetes Mellitus / Q000378:metabolism*; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D014280:Triglycerides; D014527:Uric Acid; D002784:Cholesterol
Langzeiteffekte einer Gewichtsreduktion auf Körpergewicht und metabolische Parameter bei adipösen Nichtdiabetikern und adipösen Maturity-onset-Diabetikern.