[Transient hypothyroidism after amniofetography in preterm and newborn infants (author's transl)].
Excessive iodine application before delivery produces a transient hypothyroidism in preterm and newborn babies. We report about 6 preterm and newborn babies, who developed a transient hypothyroidism after amniofetography with a combined water and fat soluble radiopaque dye. Two preterm babies died with severe cardio-respiratory insufficiency and in five babies' pulmonary function was inadequate at birth. Since we presume a relation between pulmonary function disorder and hypothyroidism in preterm babies especially, and with regard to the hazards for normal brain development, amniofetography should be avoided in pregnancy. Treatment with l-thyroxine was started on the 1 to 12th day of life and discontinued after a period of three to six weeks.
D003287:Contrast Media / Q000009:adverse effects; D005260:Female; D005333:Fetus / Q000000981:diagnostic imaging*; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000209:etiology*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000209:etiology*; D007235:Infant, Premature, Diseases / Q000188:drug therapy / Q000209:etiology; D008297:Male; D011247:Pregnancy; D011859:Radiography; D013974:Thyroxine / Q000627:therapeutic use
D003287:Contrast Media; D013974:Thyroxine
Transitorische Hypothyreose bei Früh- und Neugeborenen nach Amniofetografie während der Schwangerschaft.