Ferritin: a reliable indicator of iron supplementation in patients on chronic hemodialysis/hemofiltration treatment?
Four hundred and forty-two serum ferritin determinations were performed in 144 patients on chronic intermittent hemodialysis treatment with intravenous iron substitution and/or oral iron substitution. Iron substitution should be done individually according to regular serum ferritin determinations. Intravenous iron substitution is easier to regulate. Iron substitution exceeding 100 mg per month normally leads to a slowly progressing iron overload except in those patients with additional blood loss or on chronic hemofiltration treatment. Iron administration should not be evaluated according to ferritin levels in patients with additional complications such as active hepatitis, tumors, infectious diseases, and operations. In these cases evaluation of iron storage can only be estimated by bone marrow examination.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D001769:Blood; D005260:Female; D005293:Ferritins / Q000378:metabolism*; D006801:Humans; D007275:Injections, Intravenous; D007501:Iron / Q000008:administration & dosage / Q000627:therapeutic use*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014462:Ultrafiltration
D005293:Ferritins; D007501:Iron