[Secondary immune blood transfusion shock in calves due to the donor immune erythrocyte isoantibodies].
Experiments were carried out on 2 cows, used as donors and 10 calves at the age from 1 to 6 months, taken in the experiment as recipients. The calves were made a blood-transfusion in a dose of 9 cm(3)/kg T. from donors whose serum contained immune erythroantibodies with a titer of 1:4--1:64, directed against their erythrocytes. The recipients had not had antibodies, directed against the donors' erythrocytes. For the purposes of the investigations were used a hemalitic test and an agglutination in a vidal test-tube. The post-transfusional immune reactions and complications observed were related to the hematransfusional shock as a result of a collision between the donor's immune isoerythroantibodies and their corresponding erythrocytic antigens in the recipients. This shock is of great practical value for transfusional hematology in calves. The immune isoerythroantibodies, built up after blood transfusion of immunized, in advance, donors, were formed in 60% of the cases on the 7th--9th days afer the blood-transfusion and disappeared from peripheral blood on the 30ieth day afterwards.
D000707:Anaphylaxis / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D001803:Blood Transfusion / Q000662:veterinary*; D002417:Cattle / Q000276:immunology*; D002418:Cattle Diseases / Q000276:immunology*; D003937:Diagnosis, Differential; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D007114:Immunization / Q000662:veterinary; D007518:Isoantibodies / Q000276:immunology*; D013997:Time Factors; D065227:Transfusion Reaction
D007518:Isoantibodies
Vtorichnoimunen khemotransfuzionen shok u teleta, predizvikan ot imunite izoeritroantitela na donorite.