Coagulation studies for severe liver disease detection in a gastroenterologic department.
15 patients with clinical, histological and laboratory findings of cirrhosis were investigated. When the results of routine hemostasis tests--thrombin time, reptilase time and fibrinogen quantitation by clotting methods--were prolonged, further immunological determinations were done. Normal results in the immunological determinations together with prolonged ones obtained by clotting methods are suggestive of dysfibrinogenemic states. A possible survey of the treatment with the help of these determinations is proposed.
D000347:Afibrinogenemia / Q000175:diagnosis; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D006501:Hepatic Encephalopathy / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000150:complications; D011379:Prognosis