[Membranous glomerulonephritis during rheumatoid arthritis. Probable toxicity of diclofenac (author's transl)].
The development of membranous glomerulonephritis in a 51 year old patient suffering from rheumatoid arthritis suggested drug toxicity, and particularly of a recently developed anti-inflammatory agent, diclofenac. The toxicity is discussed in relationship to the biochemical and pharmacological properties of the molecule, the therapeutic setting and the positivity of serological tests for rheumatoid arthritis in this particular case.
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D004008:Diclofenac / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D010648:Phenylacetates / Q000009:adverse effects*
D010648:Phenylacetates; D004008:Diclofenac
Glomérulonéphrite extra-membraneuse. Toxicité probable du diclofénac au cours d'une polyarthrite rhumatoïde.