The role of zinc ion in the development of gastric ulcers in rats.
The properties of the gastric mucosal barrier and acid output were investigated in zinc deficient rats. A decline in total acid output, a significant diminution in hydrogen and sodium ion fluxes and an increase in gastric lesions suggest a marked breakdown of the gastric mucosal barrier in zinc deficient rats.
D000818:Animals; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D051381:Rats; D012964:Sodium / Q000378:metabolism; D013276:Stomach Ulcer / Q000209:etiology* / Q000378:metabolism; D014316:Tritium / Q000378:metabolism; D015032:Zinc / Q000172:deficiency*
D014316:Tritium; D012964:Sodium; D015032:Zinc