The potentiation effect of citric acid in aureomycin in turkeys.
Citric acid was used to potentiate Aureomycin by administering both materials through the drinking water of turkeys. Treatment groups receiving citric acid consistently had higher blood levels of Aureomycin than corresponding treatments receiving Aureomycin alone. Highly significant differences in tetracycline blood levels were obtained at 24 hr in one experiment and at 48 hr in a second experiment favoring citric acid treated birds.
D000284:Administration, Oral; D000818:Animals; D002751:Chlortetracycline / Q000008:administration & dosage* / Q000494:pharmacology; D002951:Citrates / Q000008:administration & dosage* / Q000494:pharmacology; D019343:Citric Acid; D004357:Drug Synergism; D013752:Tetracycline / Q000008:administration & dosage / Q000494:pharmacology; D013997:Time Factors; D014422:Turkeys / Q000097:blood / Q000378:metabolism*
D002951:Citrates; D019343:Citric Acid; D013752:Tetracycline; D002751:Chlortetracycline