A simple operative technique for chronically severing te cerebellar peduncles in neonatal rats.
The method of anaesthesia and a new operative approach to allow chronic cutting of the cerebellar peduncles in neonatal rats by a relatively atraumatic method is described in detail. The operation allows a very quick postoperative recovery time, does not cause necrosis of the cerebellum, allows choice of partial or complete pedunclectomy, and there is no incidence of infection. A postoperative regime which has yielded a very low incidence of savaging by the mother is also discussed.
D000758:Anesthesia; D000818:Animals; D000831:Animals, Newborn; D002531:Cerebellum / Q000502:physiology* / Q000601:surgery; D008722:Methods; D010424:Pentobarbital; D051381:Rats; D013525:Surgical Instruments
D010424:Pentobarbital