Liquid preservation of baboon red blood cells in acid-citrate-dextrose or citrate-phosphate-dextrose anticoagulant: effects of washing liquid-stored red blood cells.
Autologous baboon RBC stored at 4 C in acid-citrate-dextrose (ACD) or in citrate-phosphate-dextrose (CPD) for 3 weeks after collection had 24-hour 51Cr posttransfusion survival values of about 77%. When 20-day-old ACD and CPD baboon RBC were washed and then stored at 4 C for 24 hours before autotransfusion, the 24-hour 51Cr posttransfusion survival values were about 81%. These values were similar to those seen in studies of human RBC preserved in an identical manner. Our results indicated that the baboon can be used to evaluate RBC preservation techniques before human volunteers are studied.
D000818:Animals; D001793:Blood Preservation / Q000379:methods*; D001804:Blood Transfusion, Autologous; D002951:Citrates; D019343:Citric Acid; D004912:Erythrocytes; D005947:Glucose / Q000031:analogs & derivatives*; D005958:Glucosephosphates; D008297:Male; D010215:Papio / Q000097:blood
D002951:Citrates; D005958:Glucosephosphates; C002113:acid citrate dextrose; D019343:Citric Acid; C007077:citrate phosphate dextrose; D005947:Glucose