Shape of frequency-current curves in CAI pyramidal cells in the hippocampus.
Frequency-current curves for CA1 hippocampal pyramidal neurons are shown to have basically the same shape as those for spinal motoneurones, with a region of shallow slope at low frequencies, preceding a sleep linear or upward convex region at higher frequencies. The frequency range is, however, displaced towards lower frequencies. The results suggest, in a qualitative sense, that the firing behaviour of CA1 pyramidal cells is regulated by the afterhyperpolarization, at least in the low frequency range.
D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials; D006168:Guinea Pigs; D006624:Hippocampus / Q000502:physiology*; D066298:In Vitro Techniques; D009046:Motor Neurons / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D011712:Pyramidal Tracts / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology