[Idiopathic hemochromatosis: a study of pituitary function in patients and potentially affected relatives (author's transl)].
Anterior pituitary function, particularly the hypothalamus-pituitary gonadal axis, has been investigated in four patients with idiopathic hemochromatosis and in two potentially affected family members (sons) of one patient. All the patients presented a hypogonadotrophic hypogonadism. In one patient there was an associated primary testicular failure. Gonadotropin secretion was intact in the family members. The remaining pituitary functions were usually preserved, except a probable decrease of the glandular reserve of TSH in two patients, and of prolactin in one of them.
D000293:Adolescent; D000328:Adult; D006432:Hemochromatosis / Q000150:complications / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D007006:Hypogonadism / Q000209:etiology*; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010903:Pituitary Gland, Anterior / Q000503:physiopathology*; D010908:Pituitary Hormones, Anterior / Q000097:blood; D011388:Prolactin / Q000172:deficiency; D013737:Testis / Q000503:physiopathology*; D013972:Thyrotropin / Q000172:deficiency
D010908:Pituitary Hormones, Anterior; D011388:Prolactin; D013972:Thyrotropin
Hemocromatosis idiopática: estudio de la función hipofisaria en enfermos y familiares potencialmente hemocromatósicos.