An immunization method using antigen entrapped in erythrocyte ghosts.
Intraperitoneal injection into mice of dinitrophenol-conjugated ovalbumin entrapped in autologous erythrocyte ghosts gave rise to an increase of anti-dinitrophenol antibody production without use of artificial adjuvants. This technique could be useful for vaccination or other immuno-therapeutic purposes.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D002417:Cattle; D004136:Dinitrobenzenes / Q000276:immunology; D004910:Erythrocyte Membrane / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D006386:Hemagglutination Tests; D007106:Immune Sera / Q000494:pharmacology; D007114:Immunization / Q000379:methods*; D008297:Male; D051379:Mice; D010047:Ovalbumin / Q000276:immunology; D012710:Serum Albumin, Bovine / Q000276:immunology
D000941:Antigens; D004136:Dinitrobenzenes; D007106:Immune Sera; D012710:Serum Albumin, Bovine; D010047:Ovalbumin