Human semen aspartate aminotransferase and alanine aminotransferase activity in male fertility studies.
The enzymatic activities of aminotransferases AST and ALT have been measured in the semen of a group of 98 subjects undergoing fertility studies, correlated with spermatic density and motility. An AST/ALT ratio was obtained for all patients. The results indicate that there exists a correlation between both enzymes' activities and spermatic density and motility. In two cases of excretory azoospermia, an elevated AST/ALT relation was obtained, while in two cases f secretory azoospermia a low AST/ALT ratio was seen. Aminotransferase values can thus be considered a useful piece of data in the evaluation of seminal quality, and the AST/ALT ratio used more specifically in te discrimination of the various types of azoospermia.
D000410:Alanine Transaminase / Q000378:metabolism*; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D006801:Humans; D007248:Infertility, Male / Q000201:enzymology*; D008297:Male; D009845:Oligospermia / Q000201:enzymology; D012016:Reference Values; D012661:Semen / Q000201:enzymology*
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase