The effects of age on the kindling phenomenon.
Repeated unilateral electrical stimulation of the amygdala in adult rats produces generalized seizures (kindling). New data indicate that kindling can be induced in both suckling rats between 15 and 18 days old and in rats, 34 to 72 days old. However, the expression of kindling differs in the suckling rats, but not in the 34-day-old rat, perhaps as a result of the immaturity of the central nervous system.
D000367:Age Factors; D000679:Amygdala / Q000502:physiology; D000818:Animals; D004558:Electric Stimulation / Q000009:adverse effects; D051381:Rats; D012640:Seizures / Q000209:etiology*