[Structural and functional state of the vascular wall and hemostasis in chronic ischemic heart disease].
Coronarography was used to study the state of haemocoagulation in 83 patients with chronic ischaemic heart disease. No essential differences in the figures of the blood coagulation in patients with intact and slightly sclerosed coronary arteries have been found; certain parameters, the blood heparin, dissolved fibrin were changed towards hypercoagulation with the vessels intact. Marker growth of the haemocoagulation potential was seen only with total lesion of the heart arteries reaching over 50 and 75%. The rise of haemocoagulation activity was noted also as the sensitivity of microvessels to adrenaline rose. It has been concluded that in the development of hypercoagulation not only atherosclerosis of the vascular wall, but changes of its reactivity take part.
D001780:Blood Coagulation Tests; D002908:Chronic Disease; D003228:Conjunctiva / Q000098:blood supply; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003331:Coronary Vessels / Q000503:physiopathology*; D004837:Epinephrine; D006487:Hemostasis; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged
D004837:Epinephrine
Strukturno-funktsional'noe sostoianie sosudistoĭ stenki i gemostaza u bol'nykh khronicheskoĭ ishemicheskoĭ bolezn'iu serdtsa.