Effect of benzaldehyde on the proliferation of HeLa cells.
The effect of benzaldehyde on the proliferation of HeLa cells was studied in the present work. Benzaldehyde caused a dose-dependent reduction of the proliferation of HeLa cells in vitro. This effect of benzaldehyde might be caused principally by a reversible and mild growth modulation, since no serious morphological damage was observed. Delay of the S and G2 periods in the cell cycle upon addition of benzaldehyde was observed by the pulse-labeling technique using 3H-thymidine.
D001547:Benzaldehydes / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D006367:HeLa Cells / Q000187:drug effects*; D006801:Humans; D013936:Thymidine / Q000494:pharmacology; D014316:Tritium
D001547:Benzaldehydes; D014316:Tritium; D013936:Thymidine