[Experimental research on the toxicity of PVC administered orally].
The AA. report the results of two experiments carried out on 24 rats Wistar treated with PVC dust ingestion. A group received 1 g of PVC dust in distilled water for only 15 days; the second group received PVC dust mixed with standard food almost 5 months till to 15 months. Pathological findings consist in marked hyperplasia of gastro-enteric mucosa, with polipoidfigures, and in a marked activation of pulmonary linforeticular tissue with cellular atipias. In one case a subcutaneous histiocytic lymphoma was observed.
D000284:Administration, Oral; D000818:Animals; D005753:Gastric Mucosa / Q000473:pathology; D006965:Hyperplasia / Q000139:chemically induced; D007413:Intestinal Mucosa / Q000473:pathology; D011143:Polyvinyl Chloride / Q000008:administration & dosage / Q000633:toxicity*; D011145:Polyvinyls / Q000633:toxicity*; D051381:Rats
D011145:Polyvinyls; D011143:Polyvinyl Chloride
Ricerche sperimentali sulla tossicita' del PVC per via alimetare.