[Intestinal absorption of zinc during gravidity and lactation (author's transl)].
In two experimental series the absorption of zinc was continuously studied during gravidity and lactation with Sprague-Dawley rats of the same age. The absorption was measured in vitro with isolated, everted intestinal sacs. During the first third of gravidity the absorption of zinc--based on the intestinal Zn transfer to the serosal solution and the Zn uptake into the intestinal wall--rose at first slightly, during the second third it continued to increase, whereas there was a highly significant increase during the last third of gravidity in comparison to nongravid, nonlactating control animals (P less than 0.001). Shortly before parturition the absorption already started to fall and continued to do so during lactation. Therefore, Zn absorption was higher only in the first days of lactation in comparison to the controls (P less than 0.05). Reasons were discussed for these changes in the absorption during gravidity and lactation.
D000818:Animals; D005260:Female; D005865:Gestational Age; D007408:Intestinal Absorption; D007774:Lactation; D011247:Pregnancy; D051381:Rats; D015032:Zinc / Q000378:metabolism*
D015032:Zinc
Zur intestinalen Absorption von Zink während der Gravidität und Laktation.