Determination of adhesive rate constant in normal and neoplastic homogeneic cells.
The adhesive rate constant (ARC) of neoplastic SGS-2 cells which have a low contact inhibition, is remarkably higher than that of normal homogeneic fibroblasts. This is in contrast with the mutual adhesion theory which states that the loss of contact inhibition is strictly related to the loss of cell recognition and consequently to the loss of cell adhesion capacity.
D000818:Animals; D002448:Cell Adhesion; D002478:Cells, Cultured; D005347:Fibroblasts / Q000502:physiology; D007700:Kinetics; D051381:Rats; D012513:Sarcoma, Experimental / Q000503:physiopathology*