Nonhormonal adrenocortical tumor in childhood: case report.
The case of a 4-year-old boy with a large, clinically nonhormonal adrenocortical tumor is presented. The tumor was judged to be malignant and treated with excision radiotherapy, and combination chemotherapy. At 47 months from diagnosis the patient remains free of disease. Review of the literature reveals the extreme rarity of such tumors in childhood. An abdominal mass is the usual presentation and the prognosis is very poor. The degree of malignancy is often difficult to determine but large tumors are more likely to metastasize.
D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis