[Effect of sex hormones on carbohydrate metabolic indices in the lungs of hypoxic rats].
Experiments were carried out to reveal changes in the content of glucose, glycogen, pyruvate and lactate and in the activity of hexokinase and lactate dehydrogenase in the lungs of white rats exposed to 7- and 35-day hypoxia (rise to 9000 m for 6 hours daily) and treated with progesterone and testosterone. Treatment with the steroid hormones during chronic hypoxia increased the pulmonary content of glucose, glycogen, pyruvate, and decreased hexokinase activity and lactate accumulation.
D000818:Animals; D050260:Carbohydrate Metabolism; D002369:Castration; D004734:Energy Metabolism / Q000187:drug effects; D000860:Hypoxia / Q000188:drug therapy* / Q000378:metabolism; D008168:Lung / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011374:Progesterone / Q000008:administration & dosage*; D051381:Rats; D013739:Testosterone / Q000008:administration & dosage*; D013997:Time Factors
D013739:Testosterone; D011374:Progesterone
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