Temporal change in the airway resistance following stimulation of the nasal mucosa.
In the present study, the effect of stimulation of the nasal mucosa produced by gauze packing on the lower airway was evaluated in normal subjects by measuring the airway resistance with a body plethysmograph at scheduled intervals for 60 min after packing and 60 min after its removal. In subjects exhibiting rising of the airway resistance after stimulation, the value rose immediately or in 5 min after stimulation, then reverted to the pre-packing level and remained constant thereafter. In those exhibiting lowering of the airway resistance, the value fell immediately or in approximately 20 min after stimulation, rose thereafter but remained constant at a lower level than the pre-packing. The response of the lower airway due to the stimulation of the nasal mucosa has individual differences and shows a variety of patterns.
D000328:Adult; D000403:Airway Resistance; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000502:physiology*; D010812:Physical Stimulation; D010993:Plethysmography, Whole Body; D013997:Time Factors