Familial occurrence of multiple intracranial aneurysms. Case reports and review of the literature.
The authors report a family in which two members had multiple intracranial aneurysms. This is the third reported family with more than one member affected by multiple cerebral aneurysms. The congenital nature and the patterns of inheritance of the disease are discussed. The indications for elective investigation of the asymptomatic relatives are surgical prophylaxis on asymptomatic aneurysms are also briefly discussed.
D000328:Adult; D002343:Carotid Artery, Internal; D002941:Circle of Willis; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000235:genetics* / Q000601:surgery; D008297:Male