Effect of various doses of cerium on the serum level of ornithine-carbamyltransferase in rats.
The relationships between different cerium doses administered intravenously as CeCl3 and the mortality of rats and their serum OCT level were studied. The LD50/30 value for cerium given intravenously to rats was 5.56 mg Ce/kg. A directly proportional correlation was demonstrated between intravenously administered Ce doses and the serum OCT level above a threshold dose.
D000818:Animals; D002563:Cerium / Q000008:administration & dosage* / Q000633:toxicity; D056486:Chemical and Drug Induced Liver Injury / Q000401:mortality; D005260:Female; D006520:Hepatitis, Animal / Q000139:chemically induced / Q000401:mortality; D007275:Injections, Intravenous; D008099:Liver / Q000187:drug effects; D008452:Maximum Allowable Concentration; D009954:Ornithine Carbamoyltransferase / Q000097:blood*; D051381:Rats; D013268:Stimulation, Chemical
D002563:Cerium; D009954:Ornithine Carbamoyltransferase