The characterization of the area of rat mitochondrial DNA containing the large ribosomal RNA gene.
The base sequence of the Eco-RI D fragment from rat liver mtDNA, cloned in recombinant plasmid, has been analyzed, This fragment contains the genes for the 16SRNA of the large ribosomal subunit and the tRNA(Leu). Comparisons between these genes and corresponding regions either in other mitochondrial genomes or in E. coli DNA are presented, that allow some interesting evolutionary and phylogenetic considerations.
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004272:DNA, Mitochondrial / Q000032:analysis*; D008930:Mitochondria, Liver / Q000032:analysis*; D010957:Plasmids; D012335:RNA, Ribosomal / Q000235:genetics*; D051381:Rats
D004272:DNA, Mitochondrial; D012335:RNA, Ribosomal