Loperamide as a symptomatic treatment in pediatric surgery: a double-blind cross-over study.
The effects of oral loperamide, in doses of 2-6 mg per day, on the stool consistency, daily number of bowel movements and general inconvenience was investigated in seven children and juveniles suffering from incontinence and abnormal bowel habits due to congenital abnormalities. The study was conducted as a double-blind, cross-over analysis. According to the data collected loperamide essentially improves the quality of life of these patients.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005242:Fecal Incontinence / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008139:Loperamide / Q000627:therapeutic use*; D008297:Male; D010880:Piperidines / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy
D010880:Piperidines; D008139:Loperamide