Super-active enkephalin analogues. Simple tripeptide hydroxyalkylamides exhibit surprisingly high and long-lasting opioid activities.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001681:Biological Assay; D004723:Endorphins / Q000494:pharmacology*; D004745:Enkephalins / Q000494:pharmacology*; D005260:Female; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009842:Oligopeptides / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D004723:Endorphins; D004745:Enkephalins; D009842:Oligopeptides