Plasma lipoproteins with bioregulatory properties including the capacity to regulate lymphocyte function and the immune response.
Consideration of the effects of nutrition and of lipids on the immune competence and the characteristics of host resistance to neoplasia requires consideration of the plasma lipoproteins. A wide variety of regulatory effects of lipoproteins on the immune response, immune mediation pathways, cellular metabolism of the immune system, and antigen-nonspecific host resistance mediated by the lymphoid and reticuloendothelial systems has recently been recognized. Observations coupled with initial evidence for differences in lipoproteins in cancer patients suggest that lipids or lipid metabolism may be of significance in the biology of neoplasia.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D004198:Disease Susceptibility; D005354:Fibrosarcoma / Q000276:immunology; D008074:Lipoproteins / Q000008:administration & dosage / Q000276:immunology* / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D051379:Mice; D008811:Mice, Inbred DBA; D009369:Neoplasms / Q000276:immunology* / Q000473:pathology; D009747:Nutritional Physiological Phenomena; D012513:Sarcoma, Experimental / Q000276:immunology
D008074:Lipoproteins