[The rate of bone tissue deposition in the spongiosa of long bones subjected to mechanical overload].
In three dogs of various age (8-11 months, 3 years), injected twice with Alizarin red (20 mg/Kg) 27 and 7 days before sacrifice, the linear appositional growth rate of bone tissue have been studied in the distal metaphysis and epiphysis of the right radius submitted to mechanical overload by removing a piece of the ulnar shaft. The normally loaded left radius was used as control. In the overloaded metaphysis the linear appositional growth rate appeared significantly increased in the peripherally located spongiosa; no change in the linear appositional accretion of bone tissue as compared to the control was observed in the deep-seated spongiosa and in the epiphysis. These findings are briefly discussed in connection with the role presumably played by the mechanical stresses on osteogenesis.
D000818:Animals; D001846:Bone Development; D004285:Dogs; D010012:Osteogenesis; D011884:Radius / Q000254:growth & development; D013314:Stress, Mechanical
La velocità di deposizione del tessuto osseo nella spugnosa di ossa lunghe sottoposte a sovraccarico (1).