Structural changes of mitochondria in Chlamydomonas reinhardii after chloramphenicol treatment.
Ultrastructural and morphological alterations of mitochondria in the phytoflagellate Chlamydomonas reinhardii have been studied by use of serial sections after treatment with chloramphenicol. Remarkable volume changes could be observed as well as alterations in the internal fine structure of mitochondria. Under certain conditions, megamitochondria are formed with volumes exceeding 1 mum3. The changes, probably due to inhibition of mitochondrial protein synthesis, are described in some detail.
D002478:Cells, Cultured; D002696:Chlamydomonas / Q000254:growth & development / Q000502:physiology* / Q000648:ultrastructure; D002701:Chloramphenicol / Q000494:pharmacology*; D008928:Mitochondria / Q000187:drug effects*
D002701:Chloramphenicol