Five-hour half-life of mouse liver gap-junction protein.
The half-life of a gap-junction polypeptide band migrating at 21,000 Mr on SDS polyacrylamide gels isolated from mouse liver is measured to be 5 h. Two low-molecular wight bands, probably related to the 21,000 Mr material by proteolysis, have measured half-lives of 4.6 and 5.2 h. Gap junctions are labeled in vivo using the 14C-bicarbonate labeling procedure, followed by quantitative fluorography.
D000818:Animals; D006207:Half-Life; D007365:Intercellular Junctions / Q000378:metabolism*; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure*; D051379:Mice; D008970:Molecular Weight; D011506:Proteins / Q000378:metabolism*
D011506:Proteins