Fc and complement receptors on malignant tumor cells.
The Fc-C'-receptor-positive cells were investigated in tumor cell suspensions from 196 malignant tumors. The number of EA (Fc) and EAC' (C') rosettes was determined; the rosette-forming cells were identified cytologically, the cell suspensions were exposed to carbon particles, and they were grown in tissue culture. The results suggest that Fc or C' receptors might be present in malignant tumor cells as well as in host defence (inflammatory) cells invading the tumor.
D002462:Cell Membrane / Q000276:immunology; D046508:Culture Techniques; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D009369:Neoplasms / Q000276:immunology* / Q000648:ultrastructure; D011951:Receptors, Complement / Q000032:analysis*; D011961:Receptors, Fc / Q000032:analysis*; D012397:Rosette Formation
D011951:Receptors, Complement; D011961:Receptors, Fc