Optic nerve components may not be equally susceptible to damage by acrylamide.
Cells in the lateral geniculate nucleus of rats treated with the neurotoxin acrylamide were classified as X or Y according to the criterion of linear summation. Compared with control animals, they had a lower ratio of X to Y cells. It is argued that this effect may be related to differences in axon diameter, the thinner fibres in the optic nerve being more susceptible to damage.
D000178:Acrylamides / Q000494:pharmacology*; D000818:Animals; D009474:Neurons / Q000502:physiology; D009900:Optic Nerve / Q000187:drug effects / Q000502:physiology*; D010775:Photic Stimulation; D051381:Rats; D012160:Retina / Q000502:physiology; D014796:Visual Perception / Q000187:drug effects*
D000178:Acrylamides