The 5q - chromosome in a case of erythroid hypoplasia.
A case of erythroid hypoplasia with refractory anemia and an interstitial deletion of the long arm of one chromosome No. 5 is described. This 5q- anomaly has been previously described in cases of refractory anemia with erythroid hypoplasia or hyperplasia, and acute myelogenous leukemia. The relationship between the 5q- chromosome and associated clinical features is discussed together with evidence against a geographical localization.
D000368:Aged; D000748:Anemia, Macrocytic / Q000235:genetics*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002905:Chromosomes, Human, 4-5; D005260:Female; D006801:Humans; D007621:Karyotyping