Field vaccination trials against turkey coryza using a temperature-sensitive mutant of Alcaligenes faecalis.
In field trials, 14 flocks of turkeys were vaccinated against coryza (rhinotracheitis) with a temperature-sensitive mutant of Alcaligenes faecalis via drinking water. Vaccine doses of 5 to 250 million bacteria per turkey were used. Turkeys ranged in age from 2.5 to 13 weeks. Doses of 5 to 7 million bacteria did not induce complete protection. Doses of 50 million bacteria or more appeared to induce substantial immunity in most flocks. Six-week-old birds receiving doses of 90 million bacteria developed a high degree of protection against challenge with virulent A. faecalis.
D000284:Administration, Oral; D000421:Alcaligenes / Q000276:immunology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001424:Bacterial Infections / Q000517:prevention & control* / Q000662:veterinary*; D001428:Bacterial Vaccines / Q000008:administration & dosage; D009154:Mutation; D011201:Poultry Diseases / Q000517:prevention & control*; D013696:Temperature; D014422:Turkeys; D014611:Vaccination / Q000662:veterinary*
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines