Potentiation of acute chloroform nephrotoxicity by the glutathione depletor diethyl maleate and protection by the microsomal enzyme inhibitor piperonyl butoxide.
D000818:Animals; D002725:Chloroform / Q000037:antagonists & inhibitors / Q000633:toxicity*; D004357:Drug Synergism; D005978:Glutathione / Q000378:metabolism; D007672:Kidney Cortex / Q000378:metabolism; D007674:Kidney Diseases / Q000139:chemically induced*; D008297:Male; D008298:Maleates / Q000494:pharmacology*; D051379:Mice; D008813:Mice, Inbred ICR; D008862:Microsomes, Liver / Q000201:enzymology; D010882:Piperonyl Butoxide / Q000494:pharmacology*; D011335:Proadifen / Q000494:pharmacology
D008298:Maleates; D002725:Chloroform; D011335:Proadifen; C014476:diethyl maleate; D005978:Glutathione; D010882:Piperonyl Butoxide