[Histo- and biochemical characteristics of rat skeletal muscle after prolonged static loading].
For 100 days the rats were kept in vertical position, and after histo- and biochemical characteristics of the musc. gastrocnemius (fast) and musc. soleus (slow) were studied. A prolonged static loading was stated to produce increasing number of white and intermediate fibres in the m. gastrocnemius and intermediate fibres in the m. soleus. The fast and slow muscles reacted differently to the static loading; this was evident from a decreased content of glycogen in muscle fibers. A statistically important decrease in lactate dehydrogenase (LDH) activity in blood serum and the m. gastrocnemius was found, while in the m. soleus its level remained unchanged. It was found for certain that lactic acid content increased in the muscles studied, and its content did not change in blood serum. As to pyruvic acid content, it increased in blood serum, decreased in the m, gastrocnemius and did not differ from the control in the m. soleus. In the m. gastrocnemius an increased activity of slowly migrating LDH isoenzymes was noted, while in the m. soleus--that of fast migrating ones. At a prolonged static loading there was normalization in histo- and biochemical characteristics as it is at the dynamic loading.
D000818:Animals; D006003:Glycogen / Q000378:metabolism; D006651:Histocytochemistry; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D007773:Lactates / Q000032:analysis; D019344:Lactic Acid; D008297:Male; D009132:Muscles / Q000032:analysis / Q000378:metabolism*; D009928:Organ Specificity; D005082:Physical Exertion; D011187:Posture; D011773:Pyruvates / Q000032:analysis; D019289:Pyruvic Acid; D051381:Rats; D011919:Rats, Inbred Strains; D013385:Succinate Dehydrogenase / Q000378:metabolism
D007527:Isoenzymes; D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; D006003:Glycogen; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase
Gisto- i biokhimicheskaia kharakteristika skeletnykh myshts krys posle dlitel'noĭ staticheskoĭ nagruzki.