[Generative function in experimental exposure to polyvinylpyridine N-oxide].
A Soviet low-molecular weight polymeric preparation polyvinylpyridine-N-oxide in doses producing a marked antisilicotic effect (1 g/kg bw, 5 injections for 2 weeks or inhalations at a concentration of 57.9 +/- 4.11 mg/m3 for one hour a day 5 times a week over 8 months or throughout the entire pregnancy) does not affect generative function of rats or mice and progeny of two generations.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D006128:Growth / Q000187:drug effects; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D010053:Ovary / Q000187:drug effects; D011144:Polyvinylpyridine N-Oxide / Q000633:toxicity*; D011145:Polyvinyls / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000187:drug effects; D013997:Time Factors
D011145:Polyvinyls; D011144:Polyvinylpyridine N-Oxide
Izuchenie generativnoĭ funktsii v éksperimente pri vozdeĭstvii polivinilpiridin-N-oksida.