Primary leptomeningeal melanoma with epipharyngeal invasion.
A case of primary leptomeningeal malignant melanoma in a 45-year-old woman is reported. The tumour was located at the basal aspect of the brain with a larger aggregation in the left parasellar and cerebello-pontine angle regions. The tumour showed not only spinal meningeal dissemination but also infiltration into the petrous bone and along the trigeminal nerve till it reached the submucosal tissue of epipharynx. There are a few reported cases of primary leptomeningeal melanoma which invaded areas outside the central nervous system.
D001099:Arachnoid; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000556:secondary; D009305:Nasopharynx / Q000473:pathology*; D009361:Neoplasm Invasiveness; D010841:Pia Mater; D014057:Tomography, X-Ray Computed