[Effect of iodoacetamide on cell-cell adhesion of fibroblasts in the rat].
The -SH groups of rat fibroblasts of cell-coat were blocked with Iodacetamide. This substance interferes negatively on the homologous intercellular adhesion of the tested cells, with a proportional effect related to the concentration used. The meaning of -SH groups on the cell-cell interactions is discussed.
D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000187:drug effects; D007460:Iodoacetamide / Q000494:pharmacology*; D007461:Iodoacetates / Q000494:pharmacology*; D051381:Rats; D013438:Sulfhydryl Compounds / Q000502:physiology
D007461:Iodoacetates; D013438:Sulfhydryl Compounds; D007460:Iodoacetamide
Effetto della iodoacetmide sull'adesione cellula-cellula di fibroblasti di ratto.