[Can ischemia-induced wall motion abnormalities of the left ventricle be predicted by non-invasive thallium-201 scintigraphy? Comparison with the ventriculography test].
To assess the relation between stress-induced perfusion defects and wall motion abnormalities (WMA), 20 patients were studied by thallium-201 (201Tl) scintigraphy and cineventriculography at rest and during exercise. Of 100 analyzed segments, 63 were normal while 13 showed constant (scar) and 24 reversible (ischemia) perfusion defects. At peak exercise, 85% of the scar and 80% of the ischemic segments corresponded to abnormally contracting wall segments. There was a marked correlation between the extent of ischemia and the degree of WMA. The increase in abnormal scintigraphic and angiographic segments from rest to exercise was parallel by a significant deterioration in left ventricular function. It is concluded that (1) ischemic perfusion defects detected by 201Tl scintigraphy correlate well with exercise induced wall motion abnormalities, and (2) the localization, extent and degree of WMA can be predicted by non-invasive 201Tl scintigraphy.
D003327:Coronary Disease / Q000000981:diagnostic imaging*; D006334:Heart Function Tests; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011859:Radiography; D011868:Radioisotopes; D011877:Radionuclide Imaging; D012146:Rest; D013793:Thallium
D011868:Radioisotopes; D013793:Thallium
Können ischämie-bedingte Motilitäts-störungen des linken Ventrikels nicht-invasiv mit der Thallium-201-Szintigraphie diagnostiziert werden? Vergleich mit der Belastungs-Ventrikulographie.