Autorosette formation of erythrocytes on peripheral blood mononuclear cells in dogs vaccinated with canine distemper live-virus vaccine.
A time course study of the peripheral blood leukocytes of dogs vaccinated with canine distemper live virus (a paramyxovirus) vaccines showed that autorosette-forming leukocytes appeared from day 3 to day 10 after vaccination. The number of these cells peaked at day 7 when as many as 35% of mononuclear cells formed rosettes with autologous erythrocytes. In contrast, in nonvaccinated dogs, only 0.6 +/- 0.3% (standard error of the mean) of mononuclear cells formed rosettes throughout the 2-week period.
D000818:Animals; D004217:Distemper Virus, Canine / Q000276:immunology*; D007700:Kinetics; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology*; D012397:Rosette Formation; D014611:Vaccination; D014613:Vaccines, Attenuated / Q000494:pharmacology; D014765:Viral Vaccines / Q000494:pharmacology*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines