[Immunoglobulins and hyperlipoproteinemias].
With the objective of detecting autoimmune hyperlipidemias (AIH) we looked for the immunoglobulins bound to the low-density lipoproteins (test Ig-Lp): in 50 normolipidemic subjects and, in 133 hyperlipoproteinemic patients: 43 of type IIa, 34 of type IIb, 36 of type IV and 20 of Type V. The Ig-Lp was negative in the 50 normolipidemic subjects. It was positive in 26 hyperlipoproteinemic cases, including; 5 of type IIA, 3 of type IIb, 7 of type IV and 11 of type V. These results were compared to those of a previous smaller study, which had not been randomized. The present work confirms the interest of such a test. Although it does not allow to ascertain that the tested hyperlipoproteinemias are AIH, it suggests that there is a specific relation between immunoglobulins and lipoproteins.
D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood / Q000276:immunology*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008077:Lipoproteins, LDL / Q000097:blood*; D011485:Protein Binding
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D008077:Lipoproteins, LDL
Immunoglobulines et hyperlipoprotèinèmies.