[Transport of cytidinediphosphocholine in different biological models. II - Transport of (5 3H, Met 14C) cytidinediphosphocholine in isolated and perfused rat liver].
The uptake of double labeled CDP-choline by isolated and perfused rat liver has been investigated. The time course of CDP-choline uptake is different for 3H and 14C, showing the existence of the degradation process of the molecule. The identification and characterization of CDP-choline and its metabolites, in the perfusate and in the hepatic extract are performed by high pressure liquid chromatography.
D000818:Animals; D002250:Carbon Radioisotopes; D002794:Choline / Q000031:analogs & derivatives*; D002851:Chromatography, High Pressure Liquid; D003566:Cytidine Diphosphate Choline / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
D002250:Carbon Radioisotopes; D014316:Tritium; D003566:Cytidine Diphosphate Choline; D002794:Choline
Trasporto della citidindifosfocolina in differenti modelli biologici. II - Trasporto della (5 3H, Met 14C) citidindifosfocolina nel fegato di ratto isolato e perfuso.