Hemoperfusion for organic mercury detoxication?
A case is reported with suicidal ingestion of 125 g Ceresan, a fungicide containing 3.5% Hg2=s methoxyethylmercury-chloride. Final absorption of mercury was approximately 706 to 977 mg, as extrapolated from mercury eliminated in urine. Activated charcoal hemoperfusion removed only 1% to 2% of the amount absorbed. During treatment with D-penicillamine and dimercaprol, which were alternated fortnightly, the mercury elimination half life was 25 days, as calculated from blood concentrations and 23 days as calculated from urine data. Except for local cauterization of the mouth and throat, no signs of liver, kidney or central nervous system intoxication were seen within a 3-month follow-up period.
D005260:Female; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D008628:Mercury / Q000097:blood; D008630:Mercury Poisoning / Q000097:blood / Q000628:therapy*; D008875:Middle Aged
D008628:Mercury