The effect of age on cadmium retention in organs of hamsters.
Age difference of cadmium retention was investigated in hamsters after a short term cadmium exposure. Three types of organs were identified in relation to cadmium retention, i. e., the liver and testes retained an increasing amount of cadmium with increasing age, the kidney and heart showed a gradual decrease in the retention after a transient increase in young ages and the bone showed no retention. These changes seemed to be related to the de novo synthesis of metallothionein in the organ.
D000375:Aging; D000818:Animals; D002104:Cadmium / Q000378:metabolism*; D006224:Cricetinae; D008297:Male; D008668:Metallothionein / Q000378:metabolism; D014018:Tissue Distribution
D002104:Cadmium; D008668:Metallothionein