Concomitant analysis of normetanephrine and 3-methoxytyramine in brain: a new gas-liquid chromatography procedure.
A novel gas chromatographic procedure utilizing a glass capillary column and electron-capture detection is described for the simultaneous assay in brain of normetanephrine and 3-methoxytyramine, the 3-0-methylated metabolites or noradrenaline and dopamine respectively. The procedure has been used to quantitate these amines in whole rat brain and to demonstrate their post-mortem accumulation.
D000818:Animals; D001923:Brain Chemistry; D055598:Chemical Phenomena; D002621:Chemistry; D002849:Chromatography, Gas / Q000379:methods; D004298:Dopamine / Q000031:analogs & derivatives* / Q000032:analysis; D008297:Male; D009647:Normetanephrine / Q000032:analysis*; D051381:Rats
D009647:Normetanephrine; C001746:3-methoxytyramine; D004298:Dopamine