[Possible role of muscle receptors in regulating arterial pressure during shifts in acid-base balance in muscles].
It has been shown on anesthetized cats that perfusion of the gastrocnemius muscle with a solution simulating metabolic acidosis (pH 7.1, [HCO3-]-12.7 mM, PCO2- 38 mmHg) produces a threshold reflex increase in the arterial blood pressure. The relationship between the magnitude of the pressor reflexes and the decreased bicarbonate concentration and pH is depicted by a curve that consists of two areas: an initial progressive rise of the blood pressure is replaced after pH 6.6 by a more abrupt increase in the intensity of the pressor reflexes. The results indicate that the muscle receptors may take part in arterial blood pressure regulation during acid-base changes in the skeletal muscle.
D000138:Acidosis / Q000503:physiopathology*; D000818:Animals; D001794:Blood Pressure; D002415:Cats; D006863:Hydrogen-Ion Concentration; D009132:Muscles / Q000294:innervation* / Q000378:metabolism; D012018:Reflex
O vozmozhnoĭ roli myshechnykh retseptorov v reguliatsii arterial'nogo davleniia pri sdvigakh kislotno-shchelochnogo ravnosesiia v myshtse.