[Studies on the reaction of plastics with drug solutions. Part 3: The effects of the pigment content and of the colouring techniques (author's transl)].
The effects of the pigment content and of the colouring technique on stress-cracking are demonstrated by the example of the low-density polyethylene Mirathen A 13 EA. A 99% aqueous nikethamide solution was used as the drug solution. The sorption increased as the pigment content increased, which testifies to a relationship between the amount of the medium sorbed and the pharmaceutical ageing.
D000327:Adsorption; D004349:Drug Packaging; D004355:Drug Stability; D009552:Nikethamide / Q000032:analysis; D010860:Pigments, Biological; D010969:Plastics; D011095:Polyethylenes
D010860:Pigments, Biological; D010969:Plastics; D011095:Polyethylenes; D009552:Nikethamide
Untersuchungen zum Verhalten von Kunststoffen gegenüber Arzneistofflösungen. 3. Mitteilung: Einfluss des Pigmentgehaltes und der Einfärbetechnologie. 48. Mitteilung: Beiträge zur Problematik des Einsatzes von Kunststoffbehältnissen für flüssige Arzneizubereitungen.