[Effect of noradrenaline and angiotensin II on the brain and kidney blood supply with changes in systemic arterial pressure].
Hydrogen clearance was used in experiments on anesthetized cats to demonstrate that intravenous infusions of noradrenaline induced an increase in cerebral blood supply and reduction of renal blood flow both in anesthetized animals and in the presence of hypotension. In these conditions, angiotensin II lowered the cerebral and renal blood flow. Hypotension enhanced the reactions of the cerebral and renal blood flow to the action of vasopressor agents. The intensity of the reactions was consistent with the degree of vascular autocontrol preservation in the brain and kidneys.
D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000098:blood supply* / Q000187:drug effects; D002415:Cats; D003000:Clonidine / Q000494:pharmacology; D007022:Hypotension / Q000139:chemically induced / Q000503:physiopathology; D007668:Kidney / Q000098:blood supply* / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology*
D000804:Angiotensin II; D003000:Clonidine; D009638:Norepinephrine
Vliianie noradrenalina i angiotenzina II na krovosnabzhenie golovnogo gozga i pochek pri izmeneniiakh sistemnogo arterial'nogo davleniia.