Gallbladder emptying with ceruletide in oral cholecystography.
In a consecutive series of 148 patients the gallbladder emptying in oral cholecystography was investigated after administration of ceruletide given in doses of 0.3 microgram/kg body weight intramuscularly and 0.03 and 0.05 microgram/kg intravenously. No essential side effects occurred. The effect of ceruletide seems to be on a par with that of cholecystokinin. A dose of 0.3 microgram/kg was found to be sufficient to assess the gallbladder emptying, but then in a few instances the emptying is delayed--up to one hour. The bile ducts are best demonstrated after intravenous administration of 0.05 microgram/kg.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002108:Ceruletide / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002765:Cholecystography / Q000379:methods; D005260:Female; D005704:Gallbladder / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects
D002108:Ceruletide