Interaction between vancomycin and rifampin against Staphylococcus aureus.
By the time-kill method, vancomycin and rifampin were antagonistic against 43 of 50 strains of Staphylococcus aureus, whether susceptible or resistant to methicillin.
D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D012293:Rifampin / Q000494:pharmacology*; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology*
D014640:Vancomycin; D008712:Methicillin; D012293:Rifampin