The development of ordered structure in neonate rat epidermis.
The establishment of a columnar pattern of organization in rat backskin and earskin was examined by using frozen sections expanded in alkaline buffer and by labeling with 3H-TdR and autoradiography. An adult columnar pattern of organization was established earlier in backskin than earskin. In both tissues the appearance of cell columns was related to a decreasing rate of cell proliferation and, for ear, to a decreasing rate of lateral growth of the epidermis.
D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology*; D001345:Autoradiography; D001415:Back; D002455:Cell Division; D004423:Ear; D051381:Rats; D012867:Skin / Q000166:cytology*