Dietary influences on the development of sucrose acceptability in rats.
Weanling rats were placed on a high-fat diet or chow. Beginning at 5 weeks of age, they were tested for acceptability of 4 sucrose solutions of different concentrations once a week until they showed the previously established adult pattern of acceptability. Subjects on the chow diet showed a gradual transition from a juvenile to adult pattern of acceptability, that is, a progressive downward shift in the concentration of solution that is most acceptable. Subjects on the high-fat diets never showed the adult pattern but continued to display a juvenile pattern of acceptability throughout the experiment. The data obtained from the subjects on the high-fat diets are similar to those on taste preferences in obese humans.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000821:Animal Feed; D000818:Animals; D002648:Child; D004041:Dietary Fats / Q000008:administration & dosage / Q000378:metabolism; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D051381:Rats; D012737:Sex Factors; D013395:Sucrose / Q000494:pharmacology; D013649:Taste / Q000187:drug effects / Q000502:physiology*
D004041:Dietary Fats; D013395:Sucrose