[Electron microscopic findings during hypothermic storage. Preservation of the liver. I. (author's transl)].
Porcine livers were preserved by simple hypothermic storage for 6 h using plasma-protein-fraction 5%, albumin 5%, Collins C2, and Ringer-lactate. Electron-microscopic alterations primarily consist of aggregations of nuclear chromatin, marginal chromatin condensation, swelling and destruction of cristae mitochondriales, swelling and degranulation of the endoplasmic reticulum. These signs of cell damage are of varying intensity depending on the different preservation methods. The best condition of hepatocytes on the whole is guaranteed by using Collins C2-solution.
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D007036:Hypothermia, Induced; D008099:Liver / Q000473:pathology*; D008854:Microscopy, Electron; D008933:Mitochondrial Swelling; D009926:Organ Preservation / Q000379:methods*; D013552:Swine; D014021:Tissue Preservation / Q000379:methods*
D002843:Chromatin
Elektronenmikroskopische Befunde während hypothermer Lagerungskonservierung der Leber. I. Qualitative Beurteilung der Hepatocyten.