Stimulatory effect of chlorpromazine on prolactin secretion in anencephalic infants.
The effect of chlorpromazine on serum levels of PRL was studied in two anencephalic infants without identifiable hypothalamic tissue. After a single im injection of chlorpromazine, serum concentrations of PRL rose about 3-fold. This result indicates that chlorpromazine stimulates PRL release by directly acting on the pituitary gland in humans.
D000757:Anencephaly / Q000097:blood*; D002746:Chlorpromazine; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011388:Prolactin / Q000097:blood*
D011388:Prolactin; D002746:Chlorpromazine