Cardiovascular reflexes and interrelationships between sympathetic and parasympathetic activity.
Simultaneous recordings from vagal and sympathetic nerve fibers innervating the heart have enabled us to study relationships between activity in these two autonomic nerves. Our recent studies, as well as those of others, are reviewed with respect to tonic activity and reflex actions in these two autonomic efferents. Discharges of the two nerves in relation to blood pressure pulses and to respiratory cycles are reciprocal. During slower fluctuations of hemodynamic changes which occur spontaneously, such as during Mayer waves, a reciprocal relationship between activity in the two autonomic nerves is also observed. On the other hand, in reflex responses both reciprocal and non-reciprocal patterns of reactions produced by stimulations of the hypothalamus showed varied relationships between responses in the two autonomic outflows. The functional significance of the interrelationships of the activity pattern observed in vagal and sympathetic nerves is discussed with respect to control of cardiac functions.
D000818:Animals; D001921:Brain / Q000502:physiology; D002319:Cardiovascular System / Q000294:innervation*; D002628:Chemoreceptor Cells / Q000502:physiology; D004285:Dogs; D005071:Evoked Potentials; D006321:Heart / Q000294:innervation; D006439:Hemodynamics; D009046:Motor Neurons / Q000502:physiology; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011311:Pressoreceptors / Q000502:physiology; D012018:Reflex / Q000502:physiology*; D012119:Respiration; D013564:Sympathetic Nervous System / Q000502:physiology*; D013569:Synapses / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology