Hemostatic abnormalities following Echis carinatus (saw-scaled viper) envenomation in the rhesus monkey.
Hemostatic abnormalities following lethal and sublethal doses of Echis carinatus venom were studied in a subhuman primate model. The observations suggest the occurrence of disseminated intravascular coagulation of varying magnitude within a few hours of envenomation. A procoagulant effect of the venom of Echis carinatus is likely to be the major cause of the disturbance in the hemostatic mechanism.
D000818:Animals; D001778:Blood Coagulation Disorders / Q000209:etiology*; D004195:Disease Models, Animal; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D006470:Hemorrhage; D006487:Hemostasis; D008253:Macaca mulatta; D013997:Time Factors; D014757:Viper Venoms / Q000494:pharmacology*
D014757:Viper Venoms