Orbital aspergillosis: report of a case in a child.
A child developed eyelid swelling that was diagnosed in succession as an abscess, eosinophilic granuloma, malignancy, and inflammatory pseudotumor. Treatment modalities included antibiotics, radiation and corticosteroids. Repeated histologic examination finally provided the diagnosis of orbital mycosis, most consistent with aspergillosis. Despite six weeks of therapy with Amphotericin B, an exenteration was required. Amphotericin B was continued for another six weeks, and there has been no evidence of recurrent disease after two years of follow-up. The problems encountered in the diagnosis and management of this unusual infectious disease of the orbit in children are discussed in detail.
D000038:Abscess / Q000175:diagnosis; D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D002648:Child; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009916:Orbital Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D009918:Orbital Neoplasms / Q000175:diagnosis
D000900:Anti-Bacterial Agents; D000666:Amphotericin B