[Abortive activity of mimosine and its prevention (author's transl)].
18 out of 19 female mice treated orally with different levels of mimosine in the drinking water were fertile. Subcutaneous injection of mimosine (400 mg/kg) to 23 pregnant mice, in a single dose on days 5, 10, 15 or 17, resulted in death and resorption or expulsion of dead embryos, except in one, early inoculated. L-Phenylalanine (600 mg/kg) injected subcutaneously on day 17 prevented abortion in 4 out of 5 mice subsequently injected with mimosine.
D000019:Abortifacient Agents / Q000037:antagonists & inhibitors*; D000020:Abortifacient Agents, Nonsteroidal / Q000037:antagonists & inhibitors*; D000284:Administration, Oral; D000818:Animals; D005260:Female; D005327:Fetal Resorption / Q000139:chemically induced; D007279:Injections, Subcutaneous; D051379:Mice; D008898:Mimosine / Q000037:antagonists & inhibitors*; D010649:Phenylalanine / Q000494:pharmacology; D011247:Pregnancy; D011728:Pyridones / Q000037:antagonists & inhibitors*
D000019:Abortifacient Agents; D000020:Abortifacient Agents, Nonsteroidal; D011728:Pyridones; D010649:Phenylalanine; D008898:Mimosine
Acción abortiva de la mimosina y su prevención.