[Ultrastructure, metabolism and function of white blood cells during the development of an immune response and exposure to glucocorticoids. III. Effect of immunization on the number and ultrastructure of rabbit bone marrow cells].
The characteristic features of the early period after the immunization of rabbits with bovine serum albumin are the decreased content of ripe neutrophil forms, the increased numbers of eosinophils and basophils, as well as changes in the ultrastructure of granulocytes in the bone marrow. The destruction of the primary and secondary granules, vacuolization and an increase in acidic phosphatase activity can be observed in neutrophils. Each stage of immunogenesis has its characteristic ratio of various kinds of lymphocytes. In 14 days an increase in the number of lymphocyte-like mononuclear cells occurs. In their ultrastructure these cells are similar to the hypothetical colony-forming cells of the bone marrow in mice.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure; D001854:Bone Marrow Cells; D002452:Cell Count; D002682:Chinchilla; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D007114:Immunization; D008297:Male; D008854:Microscopy, Electron; D011817:Rabbits; D012710:Serum Albumin, Bovine / Q000276:immunology*; D013997:Time Factors
D012710:Serum Albumin, Bovine; D000135:Acid Phosphatase
Ul'trastruktura, metabolizm i funktsiia kletok beloĭ krovi v protsesse formirovaniia immunnogo otveta i pri vozdestvii na nego gliukokortikoidov. Soobshchenie III. Vliianie immunizatsii na chislo i ul'trastrukturu kletok kostnogo mozga krolikov.