Infection prophylaxis with silastic sponge explants in retinal detachment surgery.
In our animal model, silastic scleral sponges retained bactericidal levels of neomycin sulfate for at least 1 week, when thoroughly infiltrated prior to episcleral placement. This would provide an effective protection against acute buckle infections caused by bacteria contaminating the surgical field. Our clinical experience in 1,081 consecutive scleral buckling procedures substantiates the validity of this conclusion.
D000818:Animals; D001424:Bacterial Infections / Q000517:prevention & control*; D006801:Humans; D009355:Neomycin / Q000008:administration & dosage / Q000032:analysis; D019736:Prostheses and Implants; D011817:Rabbits; D012163:Retinal Detachment / Q000601:surgery*; D012591:Scleral Buckling / Q000009:adverse effects*; D012826:Silicone Elastomers; D013530:Surgical Wound Infection / Q000517:prevention & control*
D012826:Silicone Elastomers; D009355:Neomycin