[The cardiovascular risk profile in patients with disorders of glucose tolerance (borderline diabetes) dependent on the heredity of the diabetes].
In the statement of the profile of the cardiovascular risk of 1,780 persons evaluable data on a probable heredity of diabetes of 1st degree were got. Taking into consideration the same age groups no differences could be found concerning the heredity of diabetes between persons with carbohydrate tolerance lying in the borderline region (oral glucose tolerance test in the modification of the European study group for epidemiology of diabetes) and newly detected diabetics, whereas normal persons showed significantly more infrequently an occurrence of diabetes in near relatives. Taking into consideration the same age and sex of the comparative couples (150 biostatistic twins each) borderline diabetics with and without heredity of diabetes had an identical profile of risk with restriction to 5 generally accepted cardiovascular sizes of influence (overweight, hypertension, hypertriglyceridaemia, hypercholesterolaemia and hyperuricaemia). An existing heredity of diabetes does not increase the signs of risk associated with the carbohydrate intolerance.
D002318:Cardiovascular Diseases / Q000209:etiology*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics*; D005951:Glucose Tolerance Test; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000209:etiology; D009765:Obesity / Q000209:etiology; D012306:Risk; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood
D014280:Triglycerides; D014527:Uric Acid
Das kardiovaskuläre Risikoprofil von Personen mit gestörter Glukosetoleranz (Borderline-Diabetes) in Abhängigkeit von der Diabetesheredität.