[Hemodynamic changes in vasorenal hypertension in rats].
A gradual circulation transition from the hyperkinetic type at the early stage of the disease to the eukinetic and hypokinetic types at the steady stage was observed in rats with progressing renal hypertension. The elevation of arterial pressure on the 3-7th day of renal hypertension in the majority of cases was caused by the increased cardiac output, and at the steady hypertension stage by the increase of specific peripheral resistance. The hypotensive effect of inderal was demonstrated only in the hyperkinetic type of circulation, that gives evidence of the activation of the sympathetic nervous system.
D000818:Animals; D001794:Blood Pressure; D006334:Heart Function Tests; D006439:Hemodynamics / Q000187:drug effects; D006977:Hypertension, Renal / Q000503:physiopathology*; D006978:Hypertension, Renovascular / Q000188:drug therapy / Q000503:physiopathology*; D009638:Norepinephrine / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D011433:Propranolol; D009638:Norepinephrine
Gemodinamicheskie izmeneniia pri vazorenal'noĭ gipertenzii u krys.