[Effect of galascorbin on activity of lactate and malate dehydrogenases and their isoenzymic spectrum in experimental pyelonephritis].
It is shown that per os administration of galascorbin to animals with acute experimental pyelonephritis in a dose of 100 mg/1 kg of mass per day normalizes the total activity of lactate dehydrogenase (EC 1.1.1.27), malate dehydrogenase (EC 1.1.1.37) and their isoenzymic spectrum in kidney tissue and blood serum. The content of pyruvic and lactic acids in blood serum also normalizes, that promotes a favourable course of the disease.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D005419:Flavonoids / Q000494:pharmacology*; D047348:Hydrolyzable Tannins; D007527:Isoenzymes / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008291:Malate Dehydrogenase / Q000378:metabolism*; D011704:Pyelonephritis / Q000201:enzymology*; D011773:Pyruvates / Q000097:blood; D019289:Pyruvic Acid; D011817:Rabbits; D013634:Tannins / Q000494:pharmacology*
D004338:Drug Combinations; D005419:Flavonoids; D047348:Hydrolyzable Tannins; D007527:Isoenzymes; D007773:Lactates; D011773:Pyruvates; D013634:Tannins; D019344:Lactic Acid; C002944:galascorbin; D019289:Pyruvic Acid; D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D001205:Ascorbic Acid
Vlianie galaskorbina na aktivnost' laktat-, malatdegidrogenazy i ikh izofermentnyĭ spektr pri éksperimental'nom pielonefrite.