Slipped capital femoral epiphysis following radiation and chemotherapy.
Patients who received radiation to the proximal femoral epiphysis and chemotherapy in childhood appear to have an increased risk of subsequently developing epiphyseolysis. Every effort should be made to exclude the proximal femoral epiphysis from the radiation port whenever possible. If the epiphyseal plate is widened and irregular and the adjacent bone is sclerotic, prophylactic pinning may be indicated even in the absence of a grossly visible slip.
D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004839:Epiphyses, Slipped / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000528:radiation effects; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000528:radiation effects; D006801:Humans; D007223:Infant; D008297:Male; D010384:Pelvic Bones / Q000000981:diagnostic imaging / Q000528:radiation effects; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D011859:Radiography; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods; D012189:Retrospective Studies; D012306:Risk; D013997:Time Factors
D000970:Antineoplastic Agents