Interpretation of clinical symptoms in Hodgkin's disease.
The finding of general symptoms in Hodgkin's disease is accepted as bad prognostic sign and expression of disease activity. Results of clinical and histological classification analysis indicate the possibility of different interpretation of the presence and absence of symptoms in generalized disease. Asymptomatic generalized disease can be prognostically more serious than that of symptomatic one as it may express immunological tolerance of the tumor or acquired depression of defensive mechanisms. This conclusion is supported by preliminary data on survival of our patients in given classification groups.
D006689:Hodgkin Disease / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D006801:Humans