Fine needle aspiration biopsy: a useful tool in tumor cytogenetics with special reference to malignant lymphomas.
A methods for chromosome analysis of malignant cells by means of fine needle aspiration biopsy has been developed. The method has some obvious advantages compared to conventional surgical biopsy. During a 1-year period 25 consecutive non-Hodgkin, non-Burkitt lymphoma biopsies from 19 patients have been studied. In 14 out of 21 lymph node biopsies chromosome analysis was successful; whereas, four biopsies of subcutaneous lymphomas were unsuccessful.
D001707:Biopsy, Needle; D003582:Cytogenetics; D006801:Humans; D007621:Karyotyping / Q000379:methods*; D008223:Lymphoma / Q000235:genetics*; D008677:Metaphase