Acute renal failure, contrast media, and computer tomography.
Acute renal failure (ARF) is recognized as a potential hazard of intravenous administration of radiologic contrast media (RCM). We present a case of contrast-induced ARF which was first detected on an unenhanced computed tomographic examination of the abdomen. A number of postulated mechanisms in the pathogenesis of ARF are discussed. Multiple factors are associated with an increased probability of ARF when contrast material is given intravenously. The significance of advanced age as a risk factor is discussed. Certain predisposing circumstances are amenable to correction by the radiologist, thereby diminishing the chance of causing contrast-induced ARF.
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000000981:diagnostic imaging; D000367:Age Factors; D000368:Aged; D003287:Contrast Media / Q000009:adverse effects* / Q000378:metabolism; D005260:Female; D006207:Half-Life; D006801:Humans; D007275:Injections, Intravenous; D011860:Radiography, Abdominal; D012306:Risk; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014528:Uricosuric Agents / Q000378:metabolism
D003287:Contrast Media; D014528:Uricosuric Agents