Influence of carbohydrate intake soon plasma sorbitol concentration in normal subjects.
Nine healthy volunteers received either a normal diet or an isocaloric diet of which the carbohydrate content was reduced to 5% of the total caloric intake. Within 2 days of administration of the carbohydrate-poor diet, the concentration of sorbitol in plasma was decreased by 1.6 +/- 0.2 microM below the initial value (4.1 +/- 0.4 microM). When the subjects were returned to the normal diet, a reascension in plasma sorbitol concentration ws observed within 1 or 2 days. It is proposed tht, in normal subjects, the sorbitol concentration in plasma depends on and can be used as an indication of the carbohydrate intake.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008875:Middle Aged; D013012:Sorbitol / Q000097:blood*
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D013012:Sorbitol