Evidence for ganglion cell death during development of the ipsilateral retinal projection in the rat.
When one eye of a rat is removed at birth an increased projection to the brain is found from the remaining eye. This projection arises from the whole retina and mainly from ganglion cells which project to only one hemisphere of the brain. In the normal course of development many of these cells die and the uncrossed projection diminishes to form the normal adult pattern.
D000818:Animals; D002452:Cell Count; D004292:Dominance, Cerebral / Q000502:physiology*; D009115:Muridae; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D051381:Rats; D012160:Retina / Q000166:cytology*; D014795:Visual Pathways / Q000166:cytology