The diffusion coefficient of oxygen in respiring kidney and tumour tissue.
The diffusion coefficient and permeability, together with the oxygen uptake rate, have been measured in slices of respiring tissue. Values of these quantities are given for mouse kidney cortex and for implanted tumours of Lewis lung carcinoma in the mouse, and the fibrosarcoma SSB1a in the rat. The diffusion coefficient at 22 degrees C is 1.3 . 10(-5) . cm2 . s(-1) in the kidney, and has the higher value of 1.6 . 10(-5) . cm2 . s(-1) in both tumours. The solubility in all three tissues is similar to that in saline.
D000818:Animals; D002277:Carcinoma / Q000473:pathology; D004058:Diffusion; D005354:Fibrosarcoma / Q000473:pathology; D007668:Kidney / Q000378:metabolism*; D008175:Lung Neoplasms / Q000473:pathology; D008433:Mathematics; D051379:Mice; D009374:Neoplasms, Experimental / Q000378:metabolism*; D010101:Oxygen Consumption; D010539:Permeability; D051381:Rats; D012995:Solubility