[Effect of prolonged chronic stimulation of positive emotionogenic zones of the hypothalamus on blood lipid levels and arterial pressure].
Chronic experiments on rabbits with electrodes implanted into positive affective zones of the hypothalamus, which provided the reaction of self-stimulation during experimentation have shown that prolonged, discrete (over 2 hours daily), chronic (over 2 months stimulation of these zones in unrestrained animals does not cause stable changes in the content of blood lipids but lead to a significant lowering of arterial blood pressure. Continued stimulation (for one month more) together with daily feeding of rabbits with small doses of cholesterol (60 mg/kg bw) produced the same effect as the stimulation of the negative emotiogenic zones, namely, a greater increase of alimentary hypercholesterolemia than in animals of two control groups (non-operated and with implanted electrodes), as well as arterial blood pressure elevation.
D000818:Animals; D001794:Blood Pressure; D001931:Brain Mapping; D002682:Chinchilla; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D004558:Electric Stimulation; D004644:Emotions / Q000502:physiology*; D007031:Hypothalamus / Q000502:physiology*; D008055:Lipids / Q000097:blood*; D008297:Male; D011817:Rabbits; D014280:Triglycerides / Q000097:blood
D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
Vliianie dlitel'nogo khronicheskogo razdrazheniia polozhitel'nykh émotsiogennykh zon gipotalamusa na soderzhanie lipidov v krovi i uroven' arterial'nogo davleniia.