Esophageal function in esophageal atresia.
In order to determine the spectrum of esophageal dysfunction in repaired esophageal atresia, 14 patients were evaluated with esophageal manometry, intraluminal pH recording, and radiology. Nine patients had no difficulty in swallowing but six had symptoms suggestive of gastroesophageal (GE) reflux. On pH recording, six had evidence of GE reflux. Basal sphincter pressure was 22 mm Hg in both reflux and nonreflux patients. No patient had manometric evidence of peristalsis in the proximal esophagus, but six had peristalsis in the distal esophagus. On radiology all had a normal peristaltic stripping wave in the cervical esophagus, and peristalsis was absent in the proximal thoracic esophagus in all patients but present in the distal esophagus in five of the 10 patients studied. Esophageal dysfunction is present in all patients with repaired esophageal atresia even when symptoms are absent.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003679:Deglutition; D004933:Esophageal Atresia / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D004943:Esophagogastric Junction / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D005471:Fluoroscopy; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D001239:Inhalation; D008297:Male; D008365:Manometry; D010528:Peristalsis; D014138:Tracheoesophageal Fistula / Q000601:surgery