The effects of maternal carbohydrate (sucrose) supplementation on the growth of offspring of pregnancies with habitual caffeine consumption.
Reduced offspring growth was found following introduction of caffeine into the normal diet of rats during pregnancy and lactation. When maternal caffeine (10 mg/kg/day) was consumed together with supplementary sucrose (7 g/kg/day) the expected offspring growth reduction attributed to caffeine did not occur. It is concluded that maternal nutritional status may determine the outcome of caffeine exposure at low concentrations which mimic human usage.
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D002110:Caffeine / Q000494:pharmacology*; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D005260:Female; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D013395:Sucrose / Q000494:pharmacology*
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D002110:Caffeine; D013395:Sucrose