Metastasis of intracranial germinoma through a ventriculoperitoneal shunt.
A young man developed a tumor in the pineal region that grew along ventricular surfaces and caused obstructive hydrocephalus. Cytologic examination of cerebrospinal fluid demonstrated malignant cells consistent with germinoma. Following a ventriculoperitoneal shunt and radiotherapy, the tumor and the hydrocephalus regressed. Three years later, an intraperitoneal tumor appeared that was diagnosed by transcutaneous biopsy specimen as a germinoma. The abdominal germinoma also regressed after radiotherapy. While extracranial metastases of intracranial germinomas via shunts are probably rare, their occurrence, as exemplified by this case, argues for including protective filters in the shunts.
D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000556:secondary*; D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D004407:Dysgerminoma / Q000000981:diagnostic imaging / Q000209:etiology / Q000556:secondary*; D006801:Humans; D008297:Male; D010529:Peritoneal Cavity; D014057:Tomography, X-Ray Computed