[Therapeutic trials in schizophrenia with dialysis. State of the art and one case study (author's transl)].
The literature reveals 184 cases of chronic schizophrenia treated with dialysis, of which 51 with a good result. Success seems more frequent in women. Methodologies are often not well controlled, with poor clinical description. No confirmation of endorphin secretion can be found. However, positive results in some centers should stimulate more researches. Retrospective studies of available cases should be done to determine characteristics of responders. We have elaborated a questionnaire to select such responder patients and design controlled or cross-over studies. A placebo effect is possible in light of the magic and suggestive impact of such procedure. A mean aged 27 years, delusional for 9 years despite high doses of neuroleptics, was not helped by dialysis.
D000328:Adult; D006801:Humans; D008297:Male; D006435:Renal Dialysis; D012189:Retrospective Studies; D012559:Schizophrenia / Q000628:therapy*
Les essais de traitment de la schizophrénie par dialyse. Etat de la question, préntation d'un cas.