[Kinetics of the reaction between formaldehyde and proteins].
The reaction between formaldehyde and protein has been studied with the use of a radioactive indicator. In the presence of excess formaldehyde the reaction is kinetically of the first order. The accordance of experimental results to the kinetic scheme of a biphasic process was shown. On this basis experimental and veritable rate constants, equilibrium constants of mono- and dimetilol derivatives formation, the energy of activation and pseudothermodynamic parameters were determined. The dependence of reaction rate and degree of protein modification from formaldehyde concentration and temperature are discussed. Given results permit to optimize and control the process of interaction between formaldehyde and proteins.
D005557:Formaldehyde; D007700:Kinetics; D008433:Mathematics; D011485:Protein Binding; D011506:Proteins; D013696:Temperature; D013816:Thermodynamics
D011506:Proteins; D005557:Formaldehyde
Kineticheskoe issledovanie vzaimodeĭstviia formal'degida s belkami.