Etomidate: a valuable anaesthetic for mice.
Etomidate, a new nonbarbiturate short-acting hypnotic agent, was effective in anaesthetizing laboratory mice at a dose of 23.7 +/- 1.5 mg/kg bodyweight ip. Surgical anaesthesia developed which permitted the performance of operations upon the animals for at least 20 minutes after induction. In these mice (LACA-2 and C57-BL strains), doses up to 33 mg/kg were tolerated. Recovery from anaesthesia was uncomplicated.
D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D000830:Animals, Laboratory; D005045:Etomidate / Q000008:administration & dosage; D007093:Imidazoles / Q000008:administration & dosage; D007274:Injections, Intraperitoneal; D051379:Mice
D007093:Imidazoles; D005045:Etomidate