[Characteristics of the ultrastructural alteration in ascitic lymphoma NK/Ly cells as affected by cyclophosphane].
The ultrastructure of cells of mouse ascites lymphoma was studied by transmission electron microscopy. It was established that cyclophosphamide treatment (6 days) reduces cell concentration in ascitic fluid and alters tumor cell ultrastructure. Apart from dystrophic and necrotized ones, there are cells exhibiting the signs of active protein synthesis. Viral bodies in tumor cell cytoplasm were observed both in experimental and control animals.
D000818:Animals; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D008223:Lymphoma / Q000188:drug therapy / Q000648:ultrastructure*; D051379:Mice; D008854:Microscopy, Electron; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000648:ultrastructure
D003520:Cyclophosphamide
Osobennosti izmeneniia ul'trastruktury kletok astsitnoĭ limfomy NK/Ly pod vliianiem tsiklfofosfanom.