Synthesis and biological activities of quinoline hydrochlorides as anthelmintics.
In the present paper twenty five benzene substituted-4-amino quinoline derivatives were synthesized by condensation of 4-chloroquinolines with alkyl p-aminobenzoate or salicylate. The compounds were screened for antiacetylcholinesterase activity and also anthelmintic activity against Hymenolepis nana. Some of these compounds have shown interesting results.
D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D002800:Cholinesterase Inhibitors; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D000871:Anthelmintics; D002800:Cholinesterase Inhibitors; D011804:Quinolines