Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.
A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats. Amounts of 11 mg/kg of body weight/day or 22 mg/kg/day were given for 2, 3, or 4 days. Feces were collected for 7 days and were examined for expelled parasites. Cats were necropsied to recover retained parasites. A regimen of 22 mg/kg/day for 3 days was determined to be optimal with efficacies of 100%, 99%, and 50% against T cati, A tubaeforme, and Taenia taeniaeformis, respectively.
D000724:Ancylostomiasis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001196:Ascariasis / Q000662:veterinary*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D005243:Feces / Q000469:parasitology; D008463:Mebendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary*; D014120:Toxocariasis / Q000188:drug therapy / Q000662:veterinary*
D001562:Benzimidazoles; D008463:Mebendazole