Selenium and myocardial infarction: glutathione peroxidase in platelets.
The activity of the selenoenzyme glutathione peroxidase (EC 1.11.1.9) was determined in platelets of 15 patients with acute myocardial infarction and 13 control subjects. The platelets of the patients had significantly lower activities of the enzyme (P(t) greater than 0.99). This may be related to the pathogenesis of the disease.
D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000201:enzymology* / Q000209:etiology; D010544:Peroxidases / Q000378:metabolism*; D012643:Selenium / Q000378:metabolism*
D010544:Peroxidases; D005979:Glutathione Peroxidase; D012643:Selenium