Triamterene nephrolithiasis complicating dyazide therapy.
A case of triamterene nephrolithiasis is reported in a man after 4 years of hydrochlorothiazide-triamterene therapy for hypertension. The stone passed spontaneously and was found to contain a triamterene metabolite admixed with uric acid salts. Factors affecting triamterene nephrolithiasis are discussed and 2 previously reported cases are reviewed.
D004338:Drug Combinations; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D007669:Kidney Calculi / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D014223:Triamterene / Q000009:adverse effects* / Q000627:therapeutic use
D004338:Drug Combinations; D006852:Hydrochlorothiazide; D014223:Triamterene