Scleromyxedema associated with esophageal aperistalsis and dermal eosinophilia.
Scleromyxedema (generalized lichen myxedematosus) is a rare variant of papular mucinosis characterized clinically by generalized waxy papules and marked cutaneous induration. Histologically, there is fibromucinous infiltration of the superficial dermis. Most patients also have had a monoclonal serum protein of cathodal mobility. The case to be presented is remarkable for the following reasons: 1. the presence of esophageal aperistalsis; 2. the presence of prominent dermal eosinophilia; and 3. the absence of a serum monoclonal paraprotein.
D000328:Adult; D003680:Deglutition Disorders / Q000150:complications*; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D008558:Melphalan / Q000627:therapeutic use; D010266:Paraproteins; D012871:Skin Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D010266:Paraproteins; D008558:Melphalan