[Cerebrospinal fluid protein levels and blood-cerebrospinal fluid ratio of glucose and electrolytes in infants and children].
The cell and protein content of the cerebrospinal fluid (CSF) and the CSF/serum ratio of glucose, sodium, potassium, calcium, phosphate and chloride were investigated in 71 children without cerebromeningeal illness and aged 0-4 weeks, 5-8 weeks, 3-6 months, 7-12 months, 1-6 years and 7-14 years. The protein content of the CSF was 730 +/- 146 (530-950) mg/l for the age group 0-4 weeks, and 530 +/- 221 (270-950) mg/l for the age group 5-8 weeks. It was significantly higher than for all subsequent age groups. The CSF glucose accounted for 68-82% of the blood glucose. The serum/CSF ratio for sodium ranged from 101 to 104%, for potassium from 55 to 64%, for calcium from 48 to 70%, for phosphate from 24-29%, and for chloride from 106 to 114%. The decrease in serum and CSF potassium and phosphate concentrations from infancy to school age was significant. The greatest difference was evident in the serum/CSF calcium ratio which was significantly higher in the age groups up to 8 weeks than in the subsequent age groups. The electrolyte concentration of CSF with elevated protein and cell values did not differ significantly from CSF of children without cerebromeningeal disorders.
D000293:Adolescent; D000367:Age Factors; D001786:Blood Glucose / Q000378:metabolism*; D001798:Blood Proteins / Q000378:metabolism; D001812:Blood-Brain Barrier; D002452:Cell Count; D002555:Cerebrospinal Fluid / Q000166:cytology; D002556:Cerebrospinal Fluid Proteins / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D004573:Electrolytes / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008581:Meningitis / Q000378:metabolism
D001786:Blood Glucose; D001798:Blood Proteins; D002556:Cerebrospinal Fluid Proteins; D004573:Electrolytes
Eiweissgehalt des Liquors und Blut-Liquor-Relation der Gluykose und Elektrolyte im Säuglings- und Kindesalter.