Colony formation in agarose gels containing 2-deoxyglucose: its relationship with malignant transfusion.
At the light of the increasing evidence that malignant transformation is a multistep process the wide correlation between growth in soft agar and various degrees of tumorigenicity suggests that this could be a property of the early stages of malignant transformation. In the present paper we give evidence indicating that colony formation in agarose gels containing deoxyglucose can operate as a more restrictive criterium than growth in soft agar for malignant transformation in vitro, possibly associated to advanced stages in this process.
D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D006224:Cricetinae; D003470:Culture Media; D003847:Deoxyglucose; D007700:Kinetics; D008647:Mesocricetus; D012685:Sepharose
D003470:Culture Media; D012685:Sepharose; D003847:Deoxyglucose