Determination of mutagens, amino-alpha-carbolines in grilled foods and cigarette smoke condensate.
The amounts of 2 mutagens, 2-amino-9H-pyrido[2,3-b]indole (AC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAC), in grilled foods and cigarette smoke condensate wer3e determined by analysis system composed of HPLC and spectrofluorometer. The AC and MeAC contents of 1 g of grilled beef were 650.8 ng and 63.5 ng, respectively. They were equivalent to those of about 8 cigarettes. The smoke condensate of a blended cigarette (A) contained 79.7 ng of AC and 6.2 ng of MeAC.
D000818:Animals; D002243:Carbolines / Q000032:analysis*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D003296:Cooking; D005504:Food Analysis; D006358:Hot Temperature; D007211:Indoles / Q000032:analysis*; D008460:Meat / Q000032:analysis; D009153:Mutagens / Q000032:analysis*; D012907:Smoking
D002243:Carbolines; D007211:Indoles; D009153:Mutagens; C017821:2-amino-3-methyl-9H-pyrido(2,3-b)indole; C017822:2-amino-9H-pyrido(2,3-b)indole