Synthesis and properties of 7-hydroxyalkyl- and 7-hydroxyalkylamino-8-benzylaminotheophylline derivatives.
In a search for new compounds with cardiovascular activity several derivatives of 8-benzylaminotheophylline with hydroxyalkyl and hydroxyalkylamino substituents at 7-position have been obtained. Some of these compounds were screened for their hypotensive activity.
D000959:Antihypertensive Agents / Q000138:chemical synthesis*; D001596:Benzylamines / Q000138:chemical synthesis / Q000494:pharmacology; D013806:Theophylline / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D000959:Antihypertensive Agents; D001596:Benzylamines; D013806:Theophylline