Prolactin secretion in Cushing's disease.
PRL secretion was evaluated in 11 patients with Cushing's disease (7 women, 4 men). Basal morning levels were elevated when compared to normal subjects. PRL reactivity to TRH and hypoglycemia was normal in most patients. The 24-h mean PRL levels were elevated, with partial or total alteration of the nyctohemeral rhythm. Cure of Cushing's disease by selective pituitary adenomectomy restored a normal PRL secretion.
D000236:Adenoma / Q000601:surgery; D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003480:Cushing Syndrome / Q000378:metabolism* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery; D011388:Prolactin / Q000378:metabolism*; D012890:Sleep
D001786:Blood Glucose; D011388:Prolactin