[Collagen colitis. A new disease picture or merely a histological abnormality?].
"Collagenous colitis" has been recently defined as a new entity characterized by protracted diarrhoea, associated with subepithelial broadening of the collagen layer. A report is presented on two patients fulfilling the above criteria. Based on a critical analysis of these two cases and on prospective study of biopsies in 50 consecutive coloscopies it is concluded that a causal relationship between the enlarged collagen layer and the diarrhoea cannot be unequivocally established and hence "collagenous colitis" should not yet be considered a new entity.
D000328:Adult; D000368:Aged; D003092:Colitis / Q000473:pathology*; D003095:Collagen Diseases / Q000473:pathology*; D012809:Colon, Sigmoid / Q000473:pathology; D005260:Female; D006801:Humans; D008286:Malabsorption Syndromes / Q000473:pathology; D012007:Rectum / Q000473:pathology
Die "Kollagenkolitis". Ein neues Krankheitsbild oder blosse histologische Abnormität?