[Several indices of the functional state of the adrenals of white rats during a prescribed course of sulfadimezine and sulfamonomethoxine combined with UV-irradiation].
Chronic treatment with sulfadimesin or sulfamonomethoxin combined with UV irradiation leads to potentiation of adrenocortical function. As the observation period increases, the weight ratios of the adrenals grow which is accompanied by the decreased content of ascorbic acid in them and by the reduced weight ratios of the goiter and spleen. Combined chronic use of sulfanilamides and UV irradiation results in an increase of the total acetylating capacity of the body, especially in the day time.
D000107:Acetylation; D000311:Adrenal Glands / Q000187:drug effects* / Q000528:radiation effects; D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis; D005260:Female; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D013154:Spleen / Q000187:drug effects / Q000528:radiation effects; D013418:Sulfamethazine / Q000008:administration & dosage*; D013422:Sulfamonomethoxine / Q000008:administration & dosage*; D013424:Sulfanilamides / Q000008:administration & dosage*; D013961:Thyroid Gland / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays
D013424:Sulfanilamides; D013418:Sulfamethazine; D001205:Ascorbic Acid; D013422:Sulfamonomethoxine
Nekotorye pokazateli funktsional'nogo sostoianiia nadpochechnikov belykh krys pri kursovom naznachenii sul'fadimezina i sul'famonometoksina v sochetanii s UF-oblucheniem.