[The treatment of certain cases of sterility of infertility associated with an abnormal rise in urinary 17-ketosteroids by using cortisone derivatives (author's transl)].
45 women who were infertile with primary or secondary infertility were studied. The only abnormality that was found was biological, and it was a 24-hour excretion of urinary 17-ketosteroids higher than 35 micromoles. Treatment with cortisone derivatives resulted in 56 pregnancies, which were studied to their term whether it was abortion or delivery. The theoretical and practical aspects, as well as the diagnoses and treatments, are discussed.
D015068:17-Ketosteroids / Q000652:urine*; D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000652:urine; D011241:Prednisone / Q000627:therapeutic use*; D011247:Pregnancy; D013739:Testosterone / Q000097:blood
D015068:17-Ketosteroids; D013739:Testosterone; D003907:Dexamethasone; D011241:Prednisone
Traitement par les dérivés cortisoniques de certains cas de stérilité ou d'infécondité liés à une augmentation anormale des 17-cétostéroïdes urinaires.