The use of indomethacin in the treatment of idiopathic bladder instability.
55 patients suffering from voiding disorders associated with primary detrusor instability, have been treated with indomethacin. All patients have remained resistant to conventional medical treatment. 7 patients did not complete the clinical trial. After a 6-week trial period, the patients' symptom changes and side-effects were assessed. Only 17% of the patients who completed the trial, benefited from the treatment. Side-effects were encountered in 42% of the cases.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011453:Prostaglandins / Q000096:biosynthesis; D014555:Urination Disorders / Q000188:drug therapy*
D000893:Anti-Inflammatory Agents; D011453:Prostaglandins; D007213:Indomethacin