Effect of salbutamol on the non-pregnant human uterus in vivo. A hysterometric study in dysmenorrheic women.
Uterine tonicity has been determined by means of hysterometry on the first day of menstruation in 5 women with severe primary dysmenorrhea. The effect of intravenous infusion of salbutamol in a dose of 10 microgram/min was evaluated. The results indicate that this beta 2-receptor stimulating agent is capable of eliciting a marked decrease in uterine tonicity in dysmenorrheic women. The diminished uterine tonicity was closely associated with pain relief.
D000328:Adult; D000420:Albuterol / Q000008:administration & dosage / Q000627:therapeutic use*; D004412:Dysmenorrhea / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D014590:Uterine Contraction / Q000187:drug effects*
D000420:Albuterol