Dilated fixed pupils due to administration of high doses of dopamine hydrochloride.
Five patients were treated with dopamine in doses over 30 micrograms/kg . min in severe circulatory shock and developed fixed dilated pupils. This phenomenon was most likely attributed to the use of dopamine. Further neurological examination gave no support to cerebral damage. Therefore, dilated pupils, unreactive to light, bear no relation to the neurological status during treatment with high doses of dopamine.
D000328:Adult; D000368:Aged; D004106:Dilatation; D004298:Dopamine / Q000008:administration & dosage* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011680:Pupil / Q000187:drug effects*
D004298:Dopamine