[Comparison between serum ferritin and induced sideruria in the diagnosis of disorders of iron metabolism].
The A. compare the values of serum ferritin and Desferrioxamine (DFO)-induced sideruria on 73 patients affected by different diseases. The results may be divided into three groups: a first one concerning patients with low serum ferritin and low DFO-induced sideruria, a second one of patients with normal serum ferritin and normal DFO-induced sideruria; in the third group of patients the A. found high values of serum ferritin and high or normal values of DFO-induced sideruria. The different behaviour observed in this III group of patients mostly affected by malignancy may be ascribed, in all those cases with high ferritin and normal sideruria, to a direct production of isoferritins by cancer cells.
D000328:Adult; D000368:Aged; D003676:Deferoxamine / Q000494:pharmacology; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007501:Iron / Q000652:urine*; D008297:Male; D008659:Metabolic Diseases / Q000175:diagnosis*; D008875:Middle Aged; D009369:Neoplasms / Q000378:metabolism
D005293:Ferritins; D007501:Iron; D003676:Deferoxamine
Raffronto fra ferritinemia e sideruria provocata nella diagnostica dei dismetabolismi marziali.