The origin of telocentric chromosomes in man: a girl with tel(Xq).
A mentally retarded girl with several Turner symptoms had the chromosome constitution 46,Xtel(Xq). The abnormal X chromosome appeared to be completely telocentric and stable. It was late-replicating and formed a smaller than normal Barr body. The origin of telocentric chromosomes is discussed.
D002675:Child, Preschool; D002871:Chromosome Banding; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology; D012729:Sex Chromosome Aberrations; D014424:Turner Syndrome / Q000235:genetics*; D014960:X Chromosome