Neuroexcitatory properties of kainic acid. I) Electroencefalographic changes following intracerebral microinjections in behavioural rats. Preliminary note.
Microdoses of kainic acid injected into dorsal hippocampus, into striatum and into substantia reticularis pontis cause specific epileptic-like patterns associated with neuronal degeneration. Epileptic patterns seem to be dose-related and depend on the injected brain areas.
D000818:Animals; D001921:Brain / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography; D007276:Injections, Intraventricular; D007608:Kainic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008845:Microinjections; D011759:Pyrrolidines / Q000494:pharmacology*; D051381:Rats
D011759:Pyrrolidines; D007608:Kainic Acid