Elevated amounts of protein in C6 glial cells during the growth-inhibitory response elicited by dexamethasone.
Dexamethasone suppresses C6 glial cell proliferation in vitro. This growth-inhibitory response is accompanied by elevated amounts of acid-insoluble protein in the steroid-treated cells relative to controls. These results provide additional evidence that the glucocorticoid acts to arrest C6 cell proliferation in G2.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D003907:Dexamethasone / Q000494:pharmacology*; D007700:Kinetics; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009457:Neuroglia / Q000378:metabolism; D051381:Rats
D009419:Nerve Tissue Proteins; D003907:Dexamethasone