A new metabolite of propachlor isolated from germfree rat excreta.
2-[S-(N-Acetyl)cysteine]-isopropylacetanilide sulfoxide was isolated from the excreta of germfree rats given oral doses of 2-chloro-N-isopropylacetanilide. The metabolite was characterized by mass and nuclear magnetic resonance spectrometry on samples isolated from rats dosed with [1-14C]-and [2-13C]-2-chloro-N-iso-propylacetanilide. Artifact formation upon reaction of the sulfoxide with alcoholic HCl is discussed.
D000083:Acetanilides / Q000302:isolation & purification / Q000378:metabolism* / Q000652:urine; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005243:Feces / Q000032:analysis; D005856:Germ-Free Life; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051381:Rats
D000083:Acetanilides; D000900:Anti-Bacterial Agents; C011088:propachlor