Gradual occlusion of the portal branch with hepatic artery ligation for unresectable hepatic tumour in children.
For the surgical treatment of unresectable hepatic tumour in children we devised a method whereby the portal vein is gradually occluded. Using this new procedure, combined with ligation of the hepatic artery and intraarterial and systemic anticancer chemotherapy, there was a marked decrease in tumour size and hypertrophy of the contralateral lobe of the liver. For gradual occlusion of the portal vein we used the Ameroid constrictor, which consists of a casein derivative enclosed in a stainless steel jacket, and when applied the vessels will occlude within 7-10 days. The patients tolerated this procedure well; there was no occurrence of shock, the liver dysfunction was temporary and normal ranges were reverted to within 2-3 weeks after surgery. One patient treated in this way lived for 14 months after undergoing such surgery.
D000818:Animals; D002675:Child, Preschool; D004285:Dogs; D006499:Hepatic Artery / Q000601:surgery*; D006801:Humans; D007223:Infant; D008026:Ligation / Q000295:instrumentation; D008111:Liver Function Tests; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D009929:Organ Size; D011169:Portal Vein / Q000601:surgery*