[The Laferma reflux family, a case of multiple familial reflux].
We substantiate that five of total seven examined members of a family including the mother showed a reflux disease. Two of them had a monolateral, three a bilateral, two a vesicoureteral and three a vesicorenal reflux. Three of the examined members suffered from enuresis nocturna. All of the reflux-positive members of the family endoscopically showed gaping ostia of the ureter at the reflux-positive side. We found no criteria for an intravesical obstruction. All reflux-positive members showed a low-pressure reflux. Interestingly, only the female members exhibited a reflux. We don't know whether this case of an increased incidence of reflux disease within one family will represent a known hereditary pattern.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004775:Enuresis / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D014570:Urologic Diseases / Q000235:genetics* / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000235:genetics
Reflux-Familie "Laferma", ein Fall von gehäuften familiärem Reflux.