[Morphology and cytodynamics of oxazolone-induced cellular immune response].
Dynamics of lymphoid tissue changes induced by oxazolone, a contact allergen responsible for immune reaction of delayed type was studied. Basing on light-and electron microscopic findings and morphometrical analysis the following components of the reaction may be distinguished: an early active lymphocytic migration, a delayed paracortex proliferation and a following follicular response. In the regulation of the outflow of lymphocytes a primary role may be attributed to the endothelial lining of the postcapillary venules. For the morphological changes of endothelial cells an effect of circulating antigen specific lymphocytes may be responsible.
D000818:Animals; D002465:Cell Movement; D007111:Immunity, Cellular / Q000187:drug effects*; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology / Q000648:ultrastructure; D008213:Lymphocyte Activation; D008297:Male; D010080:Oxazoles / Q000276:immunology*; D010081:Oxazolone / Q000276:immunology*; D051381:Rats
D010080:Oxazoles; D010081:Oxazolone
Az oxazolon által kovăltott celluláris immunválasz morfológiája és citodinamikája.