Monoamine oxidase activities in human brain microvessels.
Microvessels can be easily isolated from human brain samples obtained at autopsy. Human frontal cortex MAO type A and B activities are similar in microvessel and microvessel-free preparations. In microvessels, enzyme activities and the ratio of MAO type A to type B vary among the areas studied and could selectively regulate the passage of certain amines though the blood vessel wall.
D000818:Animals; D001921:Brain / Q000098:blood supply / Q000201:enzymology*; D002196:Capillaries / Q000201:enzymology*; D002531:Cerebellum / Q000201:enzymology; D005625:Frontal Lobe / Q000201:enzymology; D006801:Humans; D007031:Hypothalamus / Q000201:enzymology; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D010627:Phenethylamines / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D013788:Thalamus / Q000201:enzymology
D010627:Phenethylamines; D012701:Serotonin; D008995:Monoamine Oxidase