Blockade by clonidine of negative pressure breathing-induced diuresis in the dog.
The effects of clonidine and dl-propranolol on negative pressure breathing-induced diuresis in chloralose-anaesthetized dog were studied. Clonidine (10 microgram/kg i.v.) suppressed the diuretic response, whereas dl-propranolol (1 mg/kg i.v.) was inactive.
D000818:Animals; D003000:Clonidine / Q000494:pharmacology*; D004231:Diuresis / Q000187:drug effects*; D004285:Dogs; D005260:Female; D008297:Male; D011312:Pressure; D011433:Propranolol / Q000494:pharmacology; D012119:Respiration
D011433:Propranolol; D003000:Clonidine