Development of the chick embryo following PGE1 treatment.
Chick embryos were treated with prostaglandin E1 (10, 20, 30, and 50 micrograms) at 48 and 72 hours incubation. Live embryos were recovered on day 9, staged, and examined for external malformations after weighing. There was no significant increase in embryonic mortality and malformation rates compared to the controls. Embryonic growth was also not affected.
D000818:Animals; D002642:Chick Embryo / Q000187:drug effects / Q000254:growth & development*; D011458:Prostaglandins E / Q000494:pharmacology*
D011458:Prostaglandins E