[Pressure-volume relation in the craniospinal cavity in the presence of supra- and subtentorial pathology. II. Changes in local intracerebral pressure subsequent to cerebrospinal fluid compression and decompression of the brain].
Comparative measurements of cerebrospinal fluid pressure (FP) and local intracerebral pressure of the interstitial fluid (ICPIF) both during their spontaneous changes and during artificial changes in cerebrospinal fluid volume were conducted in 15 neuro-oncological patients in the postoperative period. ICPIF pressure was measured by means of a double-layer perforated capsule perceiving pressure of the surrounding interstitial fluid. In patients who underwent removal of a tumor from the posterior cranial fossa ICPIF ranged from -15.8 to +9.5 mm Hg, and FP from 15 to 37.5 mm Hg. In patients subjected to removal of meningioma of the chiasmal-sellar area ICPIF ranged from -11.2 to +0.4 mm Hg, while FP ranged from 4 to 18.7 mm Hg. In artificial decrease in FP to 5 mm Hg and subsequent increase to 35-50 mm Hg, ICPIF changed as a rule, though only slightly (from 0.5 to 10 mm Hg), and often the changes in FP and ICPIF were opposite in direction. In approximately 1/3 of cases ICPIF did not change while the changes in FP ranged from 5 to 50 mm Hg. The possible causes of changes in intracerebral pressure in dosaged FP changes are discussed and a conclusion is drawn that the changes in ICPIF are not a simple reflection of FP dynamics but are linked with the effect exerted on the interstitial fluid by some factors among which are changes in intra-capillary pressure and tension in the cerebral tissue.
D001696:Biomechanical Phenomena; D001932:Brain Neoplasms / Q000601:surgery*; D003388:Cranial Fossa, Posterior; D005110:Extracellular Space; D006801:Humans; D007427:Intracranial Pressure; D008579:Meningioma / Q000601:surgery*; D009897:Optic Chiasm; D011184:Postoperative Period; D011312:Pressure; D012658:Sella Turcica
Sootnoshenie ob"em-davlenie v kraniospinal'noĭ polosti pri supra- i subtentorial'noĭ polosti pri supra- i subtentorial'noĭ patologii. Soobshchenie II. Izmenenie lokal'nogo vnutrimozgovogo davleniia pri likvornoĭ kompressii i dekompressii golovnogo mozga.