Urinary free cortisol excretion in endogenously depressed and schizophrenic patients.
In 8 endogenously depressed and 9 schizophrenic patients, the excretion of urinary free cortisol was measured. The endogenous depressives exhibited a significantly (p less than 0.01) higher excretion of free cortisol (X = 122 microgram/24 h or X = 68 microgram/24 h) when compared to schizophrenics. This finding, earlier reported by others, suggests a hypothalamic-pituitary-adrenocortical activation in endogenously depressed patients.
D003866:Depressive Disorder / Q000652:urine*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D008297:Male; D012559:Schizophrenia / Q000652:urine*; D012737:Sex Factors
D006854:Hydrocortisone