Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey.
Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D005552:Forelimb / Q000294:innervation; D006614:Hindlimb / Q000294:innervation; D008252:Macaca fascicularis; D008253:Macaca mulatta; D009412:Nerve Fibers / Q000502:physiology*; D009619:Nociceptors / Q000502:physiology*; D012867:Skin / Q000294:innervation; D012881:Skin Temperature