Contact allergy to propylene oxide and isopropyl alcohol in a skin disinfectant swab.
Two laboratory assistants developed contact dermatitis from a disposable swab for pre-injection use, containing isopropyl alcohol 70% and propylene oxide 1%. Patch testing gave position allergic reactions to propylene oxide in both patients, one of whom also reacted to isopropyl alcohol. Testing of 25 control persons gave negative results.
D000433:1-Propanol / Q000009:adverse effects*; D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D004852:Epoxy Compounds / Q000009:adverse effects*; D000431:Ethanol / Q000009:adverse effects; D004988:Ethers, Cyclic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male
D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D000431:Ethanol; D000433:1-Propanol; C009068:propylene oxide