[Immunological monitoring of patients operated on for epidermoid bronchogenic carcinoma].
Sequential monitoring of non specific immunity has been carried out in 16 patients with squamous cell bronchogenic carcinoma undergoing radical surgery. At the time of diagnosis total lymphocyte counts, T-lymphocyte counts and the blastogenic response of lymphocytes to PHA were only slightly depressed; on the contrary C3c and C4 serum levels were significantly increased (P less than 0.01). Sequential determinations of the immunologic profile at monthly intervals up to the 12th postoperative month showed a transient increase of total lymphocyte and T-lymphocyte levels; the lymphocyte blastogenic response to PHA and also C3c and C4 serum levels progressively decreased. Delayed hypersensitivity response to cutaneous antigens, neutrophil chemotaxis, serum levels of IgG, IgA, IgM and B-lymphocyte counts were constantly found within normal range.
D000328:Adult; D000368:Aged; D000917:Antibody Formation; D002283:Carcinoma, Bronchogenic / Q000276:immunology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000601:surgery; D002634:Chemotaxis, Leukocyte; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008175:Lung Neoplasms / Q000276:immunology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D009504:Neutrophils / Q000276:immunology; D011013:Pneumonectomy
Monitoraggio immunologico di pazienti operati per carcinoma broncogeno epidermoidale.