Amphetamine addiction and pregnancy. II. Pregnancy, delivery and the neonatal period. Socio-medical aspects.
The adverse effects of amphetamine addiction during pregnancy and the neonatal period were studied in 69 Swedish women. Almost one-third of the women (Group I) succeeded in overcoming their addiction in early pregnancy. The women in Group I (n = 17), unlike those in Group II (n = 53), received the same amount of prenatal care as the average Swedish woman. An increased rate of preterm deliveries (25%) as well as a higher perinatal mortality (7.5%) was found in Group II. During the neonatal period an increased incidence of mother-infant separation was found since many of the infants (46%) were transferred to pediatric wards for medical and social reasons. All newborns in Group I and 74% of infants born to mothers with continuous amphetamine addiction throughout pregnancy remained in their mother's custody following discharge from the maternity clinic.
D000014:Abnormalities, Drug-Induced; D000661:Amphetamine / Q000009:adverse effects*; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007743:Labor, Obstetric / Q000187:drug effects*; D008431:Maternal-Fetal Exchange; D007752:Obstetric Labor, Premature / Q000139:chemically induced; D011247:Pregnancy / Q000187:drug effects*; D011248:Pregnancy Complications / Q000139:chemically induced; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders / Q000150:complications*; D013548:Sweden
D000661:Amphetamine