[Effect of acetylcholine and histamine on electrolyte and catecholamine content of vessel walls exposed to x-rays and cystamine].
Experiments on adult rats have shown that a single rectal x-ray irradiation is accompanied by a decrease in the content of adrenaline, noradrenaline and potassium and by a increase in sodium and calcium concentration in vascular tissue. The degree of these shifts depends on the time elapsed after exposure to x-rays. X-Ray injury produces specific changes in the biochemical response of the vascular wall to different doses of acetylcholine and histamine during varying times of x-ray-induced pathology. Pretreatment (before irradiation) with radioprotectors (cistamine) lowers the damaging effect of radiation and promotes the normalization of the vascular tissue response to the administration of mediator agents.
D000818:Animals; D001808:Blood Vessels / Q000528:radiation effects*; D002118:Calcium / Q000528:radiation effects; D002395:Catecholamines / Q000528:radiation effects*; D002415:Cats; D003538:Cystamine / Q000494:pharmacology*; D004573:Electrolytes / Q000528:radiation effects*; D004837:Epinephrine / Q000528:radiation effects; D005260:Female; D008274:Magnesium / Q000528:radiation effects; D008297:Male; D009638:Norepinephrine / Q000528:radiation effects; D011188:Potassium / Q000528:radiation effects; D012007:Rectum / Q000098:blood supply; D012964:Sodium / Q000528:radiation effects; D014965:X-Rays
D002395:Catecholamines; D004573:Electrolytes; D012964:Sodium; D008274:Magnesium; D003538:Cystamine; D011188:Potassium; D002118:Calcium; D009638:Norepinephrine; D004837:Epinephrine
Vliianie atsetilkholina i gistamina na soderzhanie élektrolitov i katekholaminov v stenke sosudov v usloviiakh rentgenooblucheniia i deĭstviia tsistamina.