Rewarding effects of hypothalamic self-stimulation altered by unilateral lesions of superior colliculus in rats.
The effects of unilateral lesions of the superior colliculus were determined on self-stimulation of the medial forebrain bundle. It was found that the lesions had different effects depending upon the precise location of the stimulating electrode: self-stimulation on far-laterally located electrodes was abolished while on more medially placed electrodes this behaviour was enhanced. These data are inconsistent with explanations of intracranial self-stimulation which treat it as a unitary phenomenon.
D000818:Animals; D004558:Electric Stimulation; D007839:Functional Laterality; D007031:Hypothalamus / Q000502:physiology*; D051381:Rats; D012653:Self Stimulation; D013477:Superior Colliculi / Q000033:anatomy & histology / Q000502:physiology*