A rare blood group antigen, Rla (Rosenlund).
A "new' rare blood group antigen Rla (Rosenlund) is reported. The antigen is present in about 1 in 900 Norwegians. Nine unrelated Rl(a+) people were found. Studies of seven families, leading to the discovery of 20 additional Rl(a+) people, indicated the antigen is inherited as a Mendelian dominant character. Independent segregation was demonstrated between Rla and the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems, the ABH secretor genes, and sex. The Rla antigen is inactivated by papain treatment. The corresponding antibody, anti-Rla, has so far been found in three sera that also contain antibodies to other rare blood group antigens.
D000906:Antibodies; D001789:Blood Group Antigens; D006801:Humans; D007983:Lewis Blood Group Antigens; D008951:MNSs Blood-Group System; D009664:Norway; D010206:Papain / Q000494:pharmacology; D010375:Pedigree; D012709:Serum Albumin / Q000494:pharmacology; D013696:Temperature
D000906:Antibodies; D001789:Blood Group Antigens; D007983:Lewis Blood Group Antigens; D008951:MNSs Blood-Group System; D012709:Serum Albumin; D010206:Papain