Cochlear responses to dynamic click patterns in the guinea pig.
Fast cochlear adaptation, expressed as percent inhibition of the summed action potential, is studied from the guinea pig cochlea responses to click trains, ramps, and steps in both directions. The transition time function of adaptation to constant click trains does not depend on click strength, but rather on click interval. On the background of steady state adaptation, click steps produce only transient changes of the adaptive state, opposite to step direction. Compared to constant train stimulation, adaptation is enhanced by descending click ramps, and diminished or reversed (near threshold) by ascending ramps.
D000161:Acoustic Stimulation; D000222:Adaptation, Physiological; D000818:Animals; D001307:Auditory Perception / Q000502:physiology*; D003051:Cochlea / Q000502:physiology*; D003055:Cochlear Microphonic Potentials; D004193:Discrimination Learning / Q000502:physiology*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000502:physiology; D008144:Loudness Perception / Q000502:physiology; D009433:Neural Inhibition