Blood fibrinolytic system in rana tigrina.
Fibrinolytic activity as well demonstrable in the blood of Rana tigrina. There occurs prompt lysis of diluted plasma; and the plasma euglobulin fraction shows lysis on both unheated and heated fibrin (human or bovine) plates, implying the presence of plasmin-like enzyme in this fraction. The fibrinolytic activity is remarkably inhibited by the erythrocyte-lysate and is moderately enhanced by leucocytes-thrombocytes. EACA suppresses the lysis of dilute cell-free plasma clots at concentrations of 10(-4) M or more, possibly indicating the presence of plasminogen activator in the plasma. Activation of fibrinolysis by human urokinase and not by streptokinase, shows the probable presence of plasminogen and absence of proactivator.
D015119:Aminocaproic Acid / Q000494:pharmacology; D000818:Animals; D001792:Blood Platelets / Q000502:physiology; D002417:Cattle; D004912:Erythrocytes / Q000502:physiology; D005342:Fibrinolysis; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000502:physiology; D011898:Ranidae / Q000097:blood*; D012712:Serum Globulins; D013696:Temperature; D014568:Urokinase-Type Plasminogen Activator / Q000494:pharmacology
D012712:Serum Globulins; D014568:Urokinase-Type Plasminogen Activator; D015119:Aminocaproic Acid