Contact dermatitis to estradiol benzoate.
Three patients developed facial dermatitis after contact with preparations containing estradiol benzoate. Patch tests were positive to estradiol benzoate 0.1% in MEK but negative to other related estrogens including estradiol. All three patients also had positive tests to resorcinol monobenzoate and two out of three to balsam of Peru. Most likely estradiol benzoate was the primary sensitizer.
D000328:Adult; D001453:Balsams / Q000009:adverse effects; D004958:Estradiol / Q000009:adverse effects*; D004967:Estrogens / Q000009:adverse effects*; D005148:Facial Dermatoses / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010328:Patch Tests; D012118:Resorcinols / Q000009:adverse effects
D001453:Balsams; D004967:Estrogens; D012118:Resorcinols; D004958:Estradiol