Liver production of N-alkylated porphyrins caused in mice by treatment with substituted dihydropyridines. Evidence that the alkyl group on the pyrrole nitrogen atom originates from the drug.
D000478:Alkylation; D000818:Animals; D005294:Ferrochelatase / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010860:Pigments, Biological / Q000378:metabolism; D011166:Porphyrins / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology; D013329:Structure-Activity Relationship
D010860:Pigments, Biological; D011166:Porphyrins; D011725:Pyridines; D005294:Ferrochelatase