Microcomputer-based spike train analysis.
A system has been developed to analyse statistically the information contained within neuronal spike trains in the central nervous system. The system consists of a microprocessor development system, together with the peripheral components and transducers. Suitable software packages have been developed to analyse statistical parameters including the mean, variance, entropy, conditional entropy, serial correlation coefficients, Markov dependency and Markov order. By linking up the required routines, the system is capable of responding in real-time and plotting the desired results from the spike train obtained. Such system has been used to study the neuronal spike trains recorded from central vestibular neurons which could be affected by positional changes, anaesthetics and various drugs for the relief of motion sickness.
D000818:Animals; D002415:Cats; D003201:Computers; D004594:Electrophysiology; D008390:Markov Chains; D008838:Microcomputers; D009474:Neurons / Q000502:physiology*; D014726:Vestibular Nuclei / Q000502:physiology*