On the mechanism of intercellular adhesion.
Using a 2 X 2 design, the collection rates of cells from radioactively labelled single-cell suspension on cell-coated collecting surfaces were tested for a possible H-2 effect on intercellular adhesiveness. In five donor-host combinations differing in the H-2 complex, no straight advantage of syngeneic over allogeneic relationship could unequivocally be proved. Trypsin was deliberately omitted in preparing the single-cell suspension; it was shown that the cell suspension processed in this way affected the mechanism of intercellular adhesiveness to a degree at least comparable to the role played by the properties of the collecting layer cells.
D000818:Animals; D001853:Bone Marrow / Q000502:physiology; D002448:Cell Adhesion; D002478:Cells, Cultured; D005347:Fibroblasts / Q000502:physiology; D006183:H-2 Antigens / Q000235:genetics*; D008214:Lymphocytes / Q000502:physiology; D008264:Macrophages / Q000502:physiology; D051379:Mice; D008815:Mice, Inbred Strains
D006183:H-2 Antigens