Transcatheter electrocoagulation of the pulmonary artery: an experimental model in dogs for studying pulmonary thrombosis.
Transcatheter electrocoagulation (TCEC) has been shown to produce permanent arterial occlusion. This study was performed to evaluate the potential of using TCEC of the pulmonary artery as an experimental model of pulmonary thromboembolism. Fourteen lobar or first-order pulmonary arteries were occluded in ten dogs in the acute studies. Eight pulmonary arteries were occluded in eight dogs that were sacrificed 25 to 85 days after TCEC. There were permanent occlusions in seven, and all seven evidence of pulmonary infarction. The animals tolerated the procedure well. The technique may have merit as an experimental model for studying pulmonary thrombosis and infarction.
D000818:Animals; D002404:Catheterization; D004285:Dogs; D004564:Electrocoagulation; D011651:Pulmonary Artery / Q000601:surgery; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography