Formulation and clinical introduction of low osmolality contrast media.
Side-effects like pain or nausea are caused by contrast media of high osmolality. Therefore new compounds of low osmolality (1/3 of old Compounds) have been formulated. Clinical introduction has revealed better tolerance and very low rates of side-effects. Angiographies with Ioxaglate, Iopamidol or Metrizamide have become almost painless Procedures.
D000328:Adult; D000790:Angiocardiography; D000792:Angiography; D001808:Blood Vessels / Q000187:drug effects; D001812:Blood-Brain Barrier / Q000187:drug effects; D003287:Contrast Media / Q000009:adverse effects; D004912:Erythrocytes / Q000187:drug effects; D006801:Humans; D007223:Infant; D007463:Iodobenzoates / Q000009:adverse effects; D007479:Iopamidol; D007483:Iothalamic Acid / Q000031:analogs & derivatives; D007485:Ioxaglic Acid; D008793:Metrizamide; D009192:Myelography; D009994:Osmolar Concentration; D014283:Triiodobenzoic Acids
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007483:Iothalamic Acid; D007479:Iopamidol; D008793:Metrizamide; D007485:Ioxaglic Acid