Thiopyronine sensitized photodynamic effect on ribosome synthesis and ribosome content in Saccharomyces cells.
The content and the synthesis of membrane bound and free ribosomes in growing yeast cells was investigated after photodynamic treatment of the cells with thiopyronine and visible light. It was shown that the synthesis of ribosomes is inhibited after photodynamic treatment and that as a consequence, the content of ribosomes in the cell is diminished.
D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D007202:Indicators and Reagents / Q000494:pharmacology*; D007700:Kinetics; D008027:Light; D011754:Pyronine / Q000031:analogs & derivatives / Q000494:pharmacology*; D012270:Ribosomes / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D012440:Saccharomyces / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D014966:Xanthenes / Q000494:pharmacology*
D007202:Indicators and Reagents; D014966:Xanthenes; C005792:thiopyronine; D011754:Pyronine