Age, senile dementia and ventricular enlargement.
Necropsy measurements of cerebral ventricular volume and pericerebral space in senile dementia patients and age-matched controls indicate that ventricular enlargement is not an accurate diagnostic marker for cerebral atrophy. Furthermore, ventricles are of normal size for age in about 40% of all senile dementia patients including those with Alzheimer's disease.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D000544:Alzheimer Disease / Q000175:diagnosis / Q000473:pathology; D002552:Cerebral Ventricles / Q000033:anatomy & histology* / Q000473:pathology; D003704:Dementia / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged