The effects of short periods of fasting on the absorption of heavy metals.
1. Rats were deprived of food for periods of from 0 to 40 h and then given 203Pb, 203Hg, 59Fe, 64Cu, 65Zn or 45Ca by stomach tube. The absorption and retention of these metals in tissues was measured 1 h and 2 d after dosing. 2. After 16-24 h of food deprivation between two and ten times more metal was retained than after 0-12 h. 3. The effects of length of fast on metal uptake by the intestinal mucosa were greatest in the duodenum. 4. Lactate production by duodenal mucosa was halved after 12 h of food deprivation but galactose absorption was little changed after a 40 h fast.
D000818:Animals; D005215:Fasting; D005690:Galactose / Q000378:metabolism; D007408:Intestinal Absorption; D007773:Lactates / Q000378:metabolism; D008297:Male; D008670:Metals / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D007773:Lactates; D008670:Metals; D005690:Galactose