[Capillary hypoperfusion in diabetes mellitus: a comparative microscopic study on its pathogenesis and temporal manifestation in in vivo animal experiments].
In animal experimental alloxan diabetes changes the distribution of microcirculation with reduction of the nutritive capillary perfusion and simultaneous formation of hyperperfused functional microshunts. The nutritive capillary hypoperfusion is due to an increased precapillary vasoconstriction and a changed rheological behaviour of the blood with increase of the cohesive forces between the erythrocytes (aggregation of erythrocytes) and the intravascular cellular swellings.
D000818:Animals; D002196:Capillaries / Q000503:physiopathology*; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D004903:Erythrocyte Aggregation; D008643:Mesentery / Q000098:blood supply; D008833:Microcirculation / Q000503:physiopathology; D010179:Pancreas / Q000098:blood supply; D011817:Rabbits; D051381:Rats; D012039:Regional Blood Flow
Die kapilläre Unterperfusion beim Diabetes mellitus: Eine tierexperimentelle vitalmikroskopische Vergleichsstudie zu deren Pathogenese und zeitlicher Manifestation.