Establishment of normal synaptic density in deafferented olfactory cortex.
The piriform cortex has been examined in rats following neonatal deafferentation produced by olfactory bulb removal. The denervated molecular layer of the piriform cortex grows to nearly its full adult thickness and the removal olfactory bulb axons are replaced by intracortical axons. The synaptic density of the molecular layer following this rearrangement is the same as that in the normal cortex.
D000375:Aging; D000818:Animals; D002540:Cerebral Cortex / Q000254:growth & development / Q000502:physiology*; D003714:Denervation; D007839:Functional Laterality; D009830:Olfactory Bulb / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000502:physiology*