On the origin of biological systems and the role of poly-nucleotides -- the initiation of evolution, the structural basis of the genetic code and the mechanism of protein biosynthesis.
There is much information on the nature and function of biological systems in the structures of the small molecules that affect them and in the biosynthetic and other reactions in which they are involved. Combining this with biochemical and polynucleotide sequence information allows us to derive explanations for a number of biological problems that earlier were unclear or even quite obscure. Thus polynucleotide systems give a good account of the origin of life, of the genetic code and of the function of the ribosomal mechanism of protein biosynthesis. It is apparent that polynucleotides play a more important role than has been fully appreciated.
D005075:Biological Evolution; D055598:Chemical Phenomena; D002621:Chemistry; D003062:Codon / Q000032:analysis; D005815:Genetic Code; D000069497:Origin of Life; D010452:Peptide Biosynthesis; D010441:Peptide Chain Elongation, Translational; D010442:Peptide Chain Initiation, Translational; D011119:Polynucleotides / Q000502:physiology*; D012343:RNA, Transfer / Q000502:physiology; D013329:Structure-Activity Relationship
D003062:Codon; D011119:Polynucleotides; D012343:RNA, Transfer