Immunological competence of children with pyogenic meningitis.
A broad range of immunological tests was performed on 9 consecutive children with pyrogenic meningitis. Two were found to have combined IgG and IgA deficiency. One had a combination of IgG deficiency and impaired neutrophil chemotaxis. Primary immunodeficiency disorders as a predisposing cause of pyogenic meningitis may be more common than previously suspected.
D002634:Chemotaxis, Leukocyte; D002675:Child, Preschool; D004406:Dysgammaglobulinemia / Q000276:immunology*; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D017099:IgG Deficiency; D007223:Infant; D008297:Male; D008581:Meningitis / Q000276:immunology*