[Exercise-induced platelet aggregation: in vitro and ex-vivo aggregation of human platelets after administration of crystalline adrenaline and after ergometric exercise (author's transl)].
Even at an adrenaline concentration of 10(-9) mol/l, using strictly defined in-vitro flow conditions at 37 degrees C and physiological pH levels, there is a significant rise in platelet aggregation above control values (nine subjects, P lesser than 0.025). According to published reports, this concentration range is reached during physical exercise. Accordingly, there was also a rise in platelet number and spontaneous aggregation (P lesser than 0.01) in eleven healthy male subjects (average age 25, range 22-33, years) during ergometric exercise. These results and published reports indicate the potential danger of untrained elderly persons with vascular disease developing an increase in platelet aggregation during exercise.
D000328:Adult; D000367:Age Factors; D004837:Epinephrine / Q000494:pharmacology*; D006801:Humans; D008297:Male; D005082:Physical Exertion; D010974:Platelet Aggregation; D010976:Platelet Count; D012306:Risk; D013696:Temperature
D004837:Epinephrine
Belastungsinduzierte Plättchenaggregation. In-vitro- und Ex-vivo-Aggregation menschlicher Blutplättchen nach Zufuhr kristallinen Adrenalins und nach ergometrischer Belastung.