Clara cell carcinoma of the lung.
A peripheral scar adenocarcinoma of the lung was found to be composed of cells with the ultrastructural features of Clara cells. It is suggested that malignant change occurred during hyperplastic and regenerative changes of the bronchiolar epithelium in which the Clara cell was the progenitor.
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged