Effects of one- and two-stage lesions of the posterior hypothalamus on temperature regulation in the rat.
Rats received 1-stage bilateral and sequential unilateral (serial) lesions of the posterior hypothalamus and were tested for the ability to regulate body temperature after a lengthy recovery period. The groups with lesion differed from the sham-operated groups in the cold, although not under ambient or warm conditions. The fact that the serial lesion group performed the same as the 1-stage lesion groups in the cold is significant because earlier tests on these same animals revealed much better recovery after serial lesions in swimming, and a partial serial lesion effect in open field performance.
D000818:Animals; D001833:Body Temperature Regulation; D004292:Dominance, Cerebral / Q000502:physiology*; D007031:Hypothalamus / Q000502:physiology*; D007034:Hypothalamus, Posterior / Q000502:physiology; D008297:Male; D051381:Rats