Studies on neplanocin A, new antitumor antibiotic. II. Structure determination.
The structure and stereochemistry of neplanocin A was determined on the basis of its spectral and chemical evidences as [1R-(la,2a,3b)]-3-(6-amino-9-yl)-5-(hydroxy-methyl)-4-cyclopentene-1,2-diol. For the final proof of the structure, X-ray crystallographic analysis of neplanocin A was carried out.
D000241:Adenosine / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D003461:Crystallography / Q000379:methods; D008968:Molecular Conformation; D013057:Spectrum Analysis
C031096:neplanocin A; D000241:Adenosine