Ectopic human placental lactogen and beta-human chorionic gonadotropin in gastric fluid of patients with malignant and non-malignant conditions of the stomach.
Human placental lactogen (hPL) and beta-human chorionic gonadotropin (beta-hCG) in gastric aspirates and sera of 24 patients with malignant (12 patients) and non-malignant (12 patients) conditions of the stomach were studied. In patients with cancer of the stomach, hPL and beta-hCG were found to be present in gastric aspirate at higher frequency than in serum. The concentration of these hormones in gastric aspirate was higher than in serum. In 2 patients with duodenal ulcer beta-hCG was found to be present in gastric aspirate, 1 of them having the hormone in circulation as well, while none of the 12 patients with non-malignant conditions of the stomach showed presence of hPL in their gastric aspirate or serum.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000032:analysis*; D004381:Duodenal Ulcer / Q000378:metabolism; D005260:Female; D005750:Gastric Juice / Q000032:analysis*; D005753:Gastric Mucosa / Q000378:metabolism*; D006729:Hormones, Ectopic / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010928:Placental Lactogen / Q000032:analysis*; D013274:Stomach Neoplasms / Q000378:metabolism*
D006063:Chorionic Gonadotropin; D006729:Hormones, Ectopic; D010928:Placental Lactogen