[Single-dose gentamicin treatment and simultaneous localization of urinary-tract infections (author's transl)].
Single-dose gentamicin (80--120 mg; Refobacin) can be used successfully to treat significant bacteriuria in women, while at the same time differentiating between upper and lower urinary tract infection. Localization was achieved by demonstrating antibody-carrying bacteria in urine by immunofluorescence. In all 31 women with lower urinary-tract infection so treated urinary sample continued to be bacteria-free when retested one to for weeks later. On the other hand, in 22 of 25 women with renal bacteriuria the original bacteria were repeatedly isolated after treatment. Using single-dose gentamicin and subsequently re-testing urine samples, renal infections in four women were correctly diagnosed in this manner, although the initial immunofluorescence test was negative.
D000907:Antibodies, Bacterial / Q000652:urine; D001437:Bacteriuria / Q000276:immunology; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy*
D000907:Antibodies, Bacterial; D005839:Gentamicins
Einmaltherapie mit Gentamicin und gleichzeitige Lokalisation von Harnwegsinfekten.