High performance liquid chromatographic analysis of hydrocortisone acetate ointments: interlaboratory study.
An interlaboratory was carried out on a high performance liquid chromatographic method for determining hydrocortisone acetate in ointments. The method represents an alternative to the colorimetric procedure of the British Pharmacopoeia. Two samples of a commercially available hydrocortisone acetate ointment were analyzed by 14 laboratories. Column performance and precision of the assay were satisfactory. The total error standard deviation for the method was 3.69%.
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006854:Hydrocortisone / Q000031:analogs & derivatives* / Q000032:analysis; D009824:Ointments / Q000032:analysis
D009824:Ointments; C021650:hydrocortisone acetate; D006854:Hydrocortisone