[Increase in gentamicin- and tobramycin-resistant Staphylococcus aureus isolates from hospital patients (author's transl)].
The increase, during a 5-year period (1975-79), in staphylococcal infections resistant to gentamicin and tobramycin has been evaluated in various units of a large Parisian hospital. Out of 3,788 infections, 539 were due to staphylococci that were resistant to gentamicin, tobramycin and kanamycin (GKTo phenotype). All isolates were methicillin-resistant strains, and 53% belonged to serotype 18. Depending upon individual hospital units two patterns of resistance were observed: a progressive one extending to 1979, with an annual average of 9% resistant strains, and a rapid one, which culminated in 1978 with 34% resistant strains.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003428:Cross Infection / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005602:France; D005839:Gentamicins / Q000494:pharmacology*; D006748:Hospital Departments; D006801:Humans; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D013997:Time Factors; D014031:Tobramycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D014031:Tobramycin
Progression de la résistance à la gentamicine et à la tobramycine des souches de Staphylococcus aureus isolées d'infections hospitalières.