Faecal bile acids and the irritable colon syndrome.
Faecal bile acid excretion and rectosigmoid myoelectrical activity were measured on three separate occasions over a 12-month period in 21 patients with the irritable colon syndrome. The results were compared with those of a group of normal subjects. Deoxycholic acid excretion was statistically significantly lower in patients with the irritable colon syndrome. In addition, these patients had a persistently high incidence of 0.03-0.06 Hz (2-4 c/m) rectosigmoid slow-wave electrical activity. These abnormal values persisted throughout the period of the study.
D001647:Bile Acids and Salts / Q000378:metabolism*; D002635:Chenodeoxycholic Acid / Q000378:metabolism; D002793:Cholic Acids / Q000378:metabolism; D003106:Colon / Q000503:physiopathology; D003109:Colonic Diseases, Functional / Q000378:metabolism* / Q000503:physiopathology; D003840:Deoxycholic Acid / Q000378:metabolism; D004576:Electromyography; D005243:Feces / Q000032:analysis*; D006801:Humans; D008095:Lithocholic Acid / Q000378:metabolism
D001647:Bile Acids and Salts; D002793:Cholic Acids; D003840:Deoxycholic Acid; D002635:Chenodeoxycholic Acid; D008095:Lithocholic Acid