[Proliferative activity of human aortic cells normal and in atherosclerosis].
By the method of enzymatic tissue dispersing cells were taken from the intima of the normal sites of human aorta and from the sites with atherosclerotic injuries (lipid stripes and lipofibrous plaques). Under the standard conditions of primary culture, proliferative activity of these cells was compared, which was judged by the thymidine index (percentage of cells labelled by 3H-thymidine) in the culture on the 7th and 14th day. The proliferative activity of cells from the lipid stripes is higher than of cells from the normal intima. It might be suggested that lipid stripes contain cells with an increased proliferative activity.
D000328:Adult; D001011:Aorta / Q000166:cytology*; D001161:Arteriosclerosis / Q000473:pathology*; D002455:Cell Division; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
Proliferativnaia aktivnost' kletok aorty v norme i pri ateroskleroza u cheloveka.