title: Intestinal bypass surgery produces conditioned taste aversion in rats.
abstract: Intestinal bypass surgery reduced the body weight of obese humans and rats primarily by decreasing food consumption. The present study reports that jejunoileal bypass surgery in rats produces a strong and persistent conditioned taste aversion to a novel-flavored solution with which it is paired. This finding indicates that the jejunioleal bypass produces a long-lasting malaise, which may be an important factor in the anorexia and weight loss produced by the operation.
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001835:Body Weight; D003216:Conditioning, Operant / Q000502:physiology; D005260:Female; D007082:Ileum / Q000502:physiology / Q000601:surgery*; D007583:Jejunum / Q000502:physiology / Q000601:surgery*; D051381:Rats; D013649:Taste / Q000502:physiology*