title: [Hormonal transformation characteristics of endometrial adenoacanthoma in the process of progestin treatment].
abstract: Changes in the histological structure of endometrial adenoacanthoma, as a result of treatment with 17 alpha-hydroxyprogesterone capronate, are discussed. The biopsy and resected material obtained from 11 patients was studied. It was shown that hormono-therapy results in an increased structural and functional differentiation of the glandular and squamous-cell components of tumor. Sensitivity to 17 alpha-hydroxyprogesterone capronate was established in 81.1% +/- 11.6 of patients.
mesh_terms: D000077713:17 alpha-Hydroxyprogesterone Caproate; D000230:Adenocarcinoma / Q000188:drug therapy / Q000503:physiopathology*; D000328:Adult; D001706:Biopsy; D002471:Cell Transformation, Neoplastic / Q000187:drug effects / Q000473:pathology; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006908:Hydroxyprogesterones / Q000627:therapeutic use*; D008875:Middle Aged; D045167:Progesterone Congeners / Q000627:therapeutic use*; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D006908:Hydroxyprogesterones; D045167:Progesterone Congeners; D000077713:17 alpha-Hydroxyprogesterone Caproate
vernacular_title: Osobennosti gormonal'noĭ transformatsii adenoakantomy éndometriia v protsesse lecheniia progestinami.