Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis.
Administration of normal cecal homogenates decreased numbers of viable Clostridium difficile and prevented cecitis in antibiotic-challenged hamsters. Cecal anaerobes appeared to suppress C. difficile.
D000693:Anaerobiosis; D000818:Animals; D001419:Bacteria / Q000254:growth & development; D002429:Cecal Diseases / Q000209:etiology*; D002432:Cecum / Q000382:microbiology*; D003013:Clostridium / Q000254:growth & development*; D006224:Cricetinae; D004463:Ecology; D007249:Inflammation; D008297:Male; D008647:Mesocricetus; D014640:Vancomycin / Q000009:adverse effects*
D014640:Vancomycin