A typical presenile dementia. Report of an anatomo-clinical case and review of the literature.
A clinico-pathological report is given of a case of dementia of frontal type with EEG changes, associated with a diffuse neuronal loss, subcortical gliosis and laminar spongiosis in the superficial part of the 2nd cortical layer. The authors discuss the cortical biopsy and the post-mortem findings in their case. They draw a comparison between their case an two conditions known as "progressive sub-cortical gliosis" and "Kraepelin's disease" which might be a single entity "atypical presenile dementia".
D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology / Q000648:ultrastructure; D003704:Dementia / Q000473:pathology*; D003712:Dendrites / Q000648:ultrastructure; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged