title: Sperm studies in anesthesiologists.
abstract: Semen samples were collected from 46 anesthesiologists each of whom had worked a minimum of one year in hospital operating rooms ventilated with modern gas-scavenging devices. Samples collected from 26 beginning residents in anesthesiology served as controls. Concentrations of sperm and percentages of sperm having abnormal head shapes were determined for each sample. No significant differences were found between anesthesiologists and beginning residents. Limiting the analyses to men having no confounding factors (varicocele, recent illness, medications, heavy smoking, frequent sauna use) did not change the results. The sperm concentration and morphology in 13 men did not change significantly after one year of exposure to anesthetic gases. However, the group of mean who had one or more confounding factors (excluding exposure to anesthetic gases) showed significantly higher percentages of sperm abnormalities than did the group of men without such factors. These results suggest that limited exposure to anesthetic gases does not significantly affect sperm production as judged by changes in sperm concentration and morphology. These data are reassuring, but since the hospitals surveyed used modern gas-scavenging devices, men who are occupationally exposed to anesthetic gases without this protection should be studied for fuller assessment of the possible human spermatotoxic effects.
mesh_terms: D000328:Adult; D000375:Aging; D000776:Anesthesiology / Q000193:education; D000777:Anesthetics / Q000009:adverse effects*; D004781:Environmental Exposure; D006801:Humans; D007396:Internship and Residency; D008297:Male; D009873:Operating Rooms; D013076:Sperm Count; D013094:Spermatozoa / Q000002:abnormalities / Q000187:drug effects*
chemical_list: D000777:Anesthetics