title: Pattern formation along the anteroposterior axis of the chick wing: the increase in width following a polarizing region graft and the effect of X-irradiation.
abstract: A study is made of the widening of the chick limb bud that occurs after a graft of an additional polarizing region. Such buds are about 50% wider than controls, after 36 h. By contrast, growth along the proximodistal axis in unaffected. This widening is reduced by treating the host embryo with 10 Gy X-irradiation and the altered pattern of digits is consistent with a diffusible morphogen model for the specification of positional information along the anteroposterior axis.
mesh_terms: D000818:Animals; D002642:Chick Embryo; D009024:Morphogenesis / Q000528:radiation effects; D011784:Quail; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous; D014921:Wings, Animal / Q000196:embryology* / Q000528:radiation effects / Q000637:transplantation