title: Antimicrobial activity of phenolic constituents of Magnolia grandiflora L.
abstract: Three phenolic constituents of Magnolia grandiflora L. were shown to possess significant antimicrobial activity using an agar well diffusion assay. Magnolol, honokiol, and 3.5'-diallyl-2'-hydroxy-4-methoxybiphenyl exhibited significant activity against Gram-positive and acid-fast bacteria and fungi. The minimum inhibitory concentrations were determined for each compound using a twofold serial dilution assay.
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification; D001419:Bacteria / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D010944:Plants / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010636:Phenols; D010936:Plant Extracts