Dysmaturation in infants of mothers with myotonic dystrophy.
We examined the pathologic findings in four infants of mothers with myotonic dystrophy. Four of the anomalies present in these infants (nesidioblastosis, renal blastema, cryptorchidism, and patent ductus arteriosus) represent persistence of fetal organ structures or configurations. We suggest that a maturational defect may be present not only in muscle, but also in other tissues.
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D004576:Electromyography; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000503:physiopathology; D008297:Male; D009132:Muscles / Q000196:embryology* / Q000503:physiopathology; D009223:Myotonic Dystrophy / Q000235:genetics / Q000503:physiopathology*; D010179:Pancreas / Q000503:physiopathology; D014057:Tomography, X-Ray Computed