Relative afferent pupillary defects in optic neuritis.
We measured relative afferent pupillary defects in 105 patients with various stages of optic neuritis. We detected pupillary defects in 96% of acute unilateral cases, 92% of recovered unilateral cases 91.7% of acute cases with evidence of optic neuropathy in the other eye, and 65.8% of recovered bilateral cases. With careful testing, one can find relative afferent pupillary defects in nearly all patients with unilateral optic neuritis and in most patients with bilateral disease. A patient without a pupillary defect after apparent unilateral optic neuritis frequently has evidence of disease in the other eye when visual-evoked potentials are tested.
D005074:Evoked Potentials, Visual; D006801:Humans; D009902:Optic Neuritis / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D012021:Reflex, Abnormal / Q000175:diagnosis*; D012025:Reflex, Pupillary; D014786:Vision Disorders / Q000209:etiology