[Characteristic ultrastructural features of parathyroid gland cancer. A report on 9 cases (author's transl)].
Authors have studied 9 parathyroid carcinomas under electron microscope (3% of their parathyroid lesions). Two types of the ultrastructural features were significant: 1) architectural: basal membrane abnormalities, sparse desmosomes, absence of nerve fiber; 2) cytological: nuclei atypism and abnormal mitochondria in tumors cells resembling dark chief cells. Also noticed were signs of cell hyperactivity and/or trouble in parathormon production or regulation.
D000230:Adenocarcinoma / Q000648:ultrastructure; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006056:Golgi Apparatus / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008928:Mitochondria / Q000648:ultrastructure; D010282:Parathyroid Neoplasms / Q000648:ultrastructure*
Particularités ultrastructurales du cancer des glandes parathyroïdes. A propos de 9 observations.