title: Effect of sex steroids on pituitary and serum prolactin level in ovariectomized catfish, Clarias batrachus.
abstract: In bilaterally ovariectomized specimens of Clarias batrachus effects of 17 beta-estradiol and testosterone propionate (TP) treatment on prolactin content of the pituitary gland and blood serum were investigated. Once daily injection of- beta estradiol (100 microgram/fish augmented the release of prolactin without altering its synthesis. Higher dose of this steroid (150 microgram/fish) significantly accelerated the synthesis and release of prolactin. Similar treatment with TP was uneffective in ovariectomized C. batrachus. It was evident from the data that 17 beta-estradiol is one of the effective regulators of prolactin secretion in female C. batrachus.
mesh_terms: D000818:Animals; D002369:Castration; D004305:Dose-Response Relationship, Drug; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D005399:Fishes / Q000502:physiology*; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism*; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D013739:Testosterone; D004958:Estradiol; D011388:Prolactin