Cytotoxicity of a hybrid prepared by coupling diphtheria toxin A-chain with immunoglobulin Fab' with N,N'-o-phenylenedimaleimide.
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D004167:Diphtheria Toxin / Q000494:pharmacology; D004220:Disulfides; D007140:Immunoglobulin Fab Fragments; D007939:Leukemia L1210 / Q000503:physiopathology; D008301:Maleimides; D008623:Mercaptoethanol; D051379:Mice; D055503:Protein Multimerization
D004167:Diphtheria Toxin; D004220:Disulfides; D007140:Immunoglobulin Fab Fragments; D008301:Maleimides; D008623:Mercaptoethanol; C023860:N,N'-2-phenylenedimaleimide