7 beta -hydroxycardenolide glycosides.
The microbial transformation of digitoxin (I) by Streptomyces sp. yielded digoxin (III) as main product along with the by-products 7beta -hydroxydigitoxin (II) and 7beta -hydroxydigoxin (IV). The present paper is concerned with the structure elucidation of 7beta-hydroxycardenolides as well as with the formation of some of their derivatives.
D001711:Biotransformation; D002855:Chromatography, Thin Layer; D004074:Digitoxin / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D004077:Digoxin / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013302:Streptomyces / Q000378:metabolism*
C031853:7-hydroxydigitoxin; C031852:7-hydroxydigoxin; D004077:Digoxin; D004074:Digitoxin