title: [Essential mixed cryoglobulinaemia and hepatitis B virus (author's transl)].
abstract: Essential mixed cryoglobulinaemia is a nosological entity described by Meltzer and Franklin in 1966 and characterized by asthenia, arthralgias, purpura, glomerulonephritis and mixed IgM-IgG cryoglobulinaemia. Hepatitis B virus (HBV) markers were studied in the sera and cryoprecipitates of 6 patients with the syndrome. Five (83,3%) had at least one HBV marker and three (50%) had HBsAg either in the serum or in the cryoprecipitate. HBV therefore seems to be involved in the pathogenesis of essential mixed cryoglobulinaemia in a large number of cases.
mesh_terms: D003449:Cryoglobulinemia / Q000209:etiology* / Q000276:immunology; D005260:Female; D006509:Hepatitis B / Q000097:blood*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000209:etiology*; D011863:Radioimmunoassay
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Cryoglobulinémie mixte essentielle: relations avec le virus de l'hépatite B.