Large differences in metabolic activation and inactivation of chemically closely related compounds: effects of pure enzymes and enzyme induction on the mutagenicity of the twelve monomethylated benz[a]anthracenes, 7,12-dimethylbenz[a]anthracene and benz[a]anthracene in the Ames test.
D000818:Animals; D001140:Aroclors / Q000494:pharmacology; D001551:Benz(a)Anthracenes / Q000378:metabolism / Q000633:toxicity*; D001711:Biotransformation; D020111:Chlorodiphenyl (54% Chlorine); D004790:Enzyme Induction / Q000187:drug effects; D004798:Enzymes / Q000378:metabolism; D004851:Epoxide Hydrolases / Q000494:pharmacology; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D008809:Mice, Inbred C3H; D009152:Mutagenicity Tests; D009153:Mutagens / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology
D001140:Aroclors; D001551:Benz(a)Anthracenes; D004798:Enzymes; D009153:Mutagens; D020111:Chlorodiphenyl (54% Chlorine); D008748:Methylcholanthrene; D004851:Epoxide Hydrolases; D010634:Phenobarbital