title: The influence of splenic tissue implantation upon platelet population in rabbits after splenectomy.
abstract: An investigation of the behavior of the blood platelet population following splenectomy and autologous splenic tissue implantation has been done on the rabbit. A bimodal rise in platelet size and count is observed in the postoperative period. After splenectomy, a 722 per cent increase in the platelet count and a 21.9 percent rise in the platelet size are found. These increases are abolished by the implantation of splenic tissue. The existence of a splenic humoral factor that controls platelet production in the bone marrow is possible.
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D001853:Bone Marrow / Q000502:physiology; D008099:Liver / Q000502:physiology; D010976:Platelet Count; D011817:Rabbits; D013154:Spleen / Q000502:physiology / Q000637:transplantation*; D013156:Splenectomy; D013922:Thrombocytosis / Q000209:etiology