Systemic infection with Trichosporon cutaneum in a patient with acute leukemia: report of a case.
A case of disseminated infection with Trichosporon cutaneum, a fungus that causes white piedra, is described. The patient, a 58-year-old barber with acute leukemia, had fever, myalgias and skin lesions. He was receiving cytotoxic drug therapy and prednisone, was severely neutropenic and was being treated with broad spectrum antibiotics. Blood cultures and a biopsy of the skin lesion grew T. cutaneum. He died despite amphotericin B therapy. At autopsy, widespread infection with T. cutaneum was present. T. cutaneum is another fungus capable of causing widespread systemic disease in the immunocompromised host.
D000666:Amphotericin B / Q000627:therapeutic use; D004848:Epithelium / Q000382:microbiology; D006801:Humans; D007938:Leukemia / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D012867:Skin / Q000382:microbiology
D000666:Amphotericin B