Neuropathology of the brain stem in psychiatric disorders.
The brain stem was examined in a series of 27 autopsy cases for a possible association of microscopic changes and primary psychiatric disorder. Seven cases were found to have brain stem microglial nodules or perivascular infiltrates in association with a range of CNS pathological conditions. One of eight schizophrenic and none of four primary affective disorder patients showed brain stem pathology. While evident in many forms of coarse brain disease, brain stem microscopic changes do not appear related to primary psychiatric disorder.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000473:pathology; D001925:Brain Damage, Chronic / Q000473:pathology; D001933:Brain Stem / Q000473:pathology*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000473:pathology*; D008875:Middle Aged; D019964:Mood Disorders / Q000473:pathology; D019965:Neurocognitive Disorders / Q000473:pathology; D009457:Neuroglia / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure; D012559:Schizophrenia / Q000473:pathology