[Capacity of some streptococcal strains to absorb in a specific manner, fractions of human blood].
We valued the capacity to bind immunoglobulins (Ig) G, M and A, albumin, haptoglobin and beta-lipoproteins of human serum by 80 strains of Streptococcus pyogenes and 30 other Streptococci groups. Specific binding were observed between Streptococci belonging to group A, C and G and some serum proteins. The binding varied remarkably among strains. The elevated capacity demonstrated by some strains to absorb IgG and IgA (and in poor degree (IgM) seems particularly interesting. It seems that this binding does not depend on the growth phase of microorganisms, also if the absorption in some cases can be greater in fixed time.
D001798:Blood Proteins / Q000378:metabolism*; D006242:Haptoglobins / Q000378:metabolism; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism; D013291:Streptococcus / Q000378:metabolism*
D001798:Blood Proteins; D006242:Haptoglobins; D007136:Immunoglobulins; D008077:Lipoproteins, LDL; D012709:Serum Albumin
Capacita' di alcuni ceppi di streptococchi di assorbire in modo specifico frazioni del siero umano.