title: A case of prenylamine toxicity showing the torsade de pointes phenomenon in sinus rhythm?
abstract: A case of torsade de pointes attributed to prenylamine is described. In addition, the authors show QRS axis variation of a similar nature in sinus rhythm. It is postulated that these changes of QRS axis direction, seen in ventricular tachycardia and sinus rhythm, are both manifestations of partial refractoriness, within the ventricle, producing gross changes in the mean QRS vector.
mesh_terms: D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D011299:Prenylamine / Q000009:adverse effects*; D013610:Tachycardia / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D011299:Prenylamine