[Status of the coagulant and anticoagulant systems of the blood in experimental acute intestinal dehydration of the body].
Acute intestinal dehydration induced in rabbits by administration into the stomach of 50 ml of castor oil produced hypercoagulation in all stages of dehydration. Hypercoagulation increased as the degree of body dehydration rose. In the first and second stages of dehydration (body mass loss from 1 to 5 and from 6 to 10%, respectively), the development of hypercoagulation was accompanied by the activation of anticoagulative system function: the increase in the total and non-enzymatic fibrinolytic activity and reduction in the activity of antiplasmins. At a stronger degree of dehydration (body mass loss from 11 to 15%) the increase of the enzymatic fibrinolytic activity was negligible, while the activation of non-enzymatic fibrinolysis was absent.
D000208:Acute Disease; D000818:Animals; D001777:Blood Coagulation; D002368:Castor Oil; D003681:Dehydration / Q000097:blood* / Q000209:etiology; D003967:Diarrhea / Q000139:chemically induced / Q000150:complications*; D004195:Disease Models, Animal; D005342:Fibrinolysis; D011817:Rabbits
D002368:Castor Oil
Sostoianie svertyvaiushcheĭ i protivosvertyvaiushcheĭ sistem krovi pri éksperimental'nom ostrom kishechnom obezvozhivanii organizma.