title: [Comparison of 2 protocols of polychemotherapy in the treatment of invasive carcinoma of the breast].
abstract: Two protocols, namely VAME (VCR, ADR, MTX, DEDX) and CMF (CTX, MTX, 5 FU), were used in the treatment of 77 menopausal patients with invasive breast cancer at the Savona Oncological Hospital between December 1976 and November 1980. CR + PR was obtained in 81.25% of those treated with VAME (group 1) and 55.18% of those treated with CMF (group B). The median and overall percentage of survival was higher in group A, and the free interval was longer, especially in patients with PR. This protocol also caused fewer subjective and objective disturbances and is thus regarded as more satisfactory, particularly since the main aim of antiblastic management is to improve and length and the quality of life.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000401:mortality; D002277:Carcinoma / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Raffronto comparativo tra due protocolli polichemioterapici nel trattamento del carcinoma invasivo della mammella.