title: Effect of blue light on the urinary excretion of tryptophan metabolites in adult heterozygous and homozygous Gunn rats.
abstract: Tryptophan metabolism along the kynurenine pathway has been studied in male and female heterozygous and homozygous adult Gunn rats after load of amino acid before and after exposure to blue light. The percentage of tryptophan metabolites in each group of rats was slightly higher in females than in males. Before irradiation the excretion of metabolites was larger in male and female heterozygous groups than the corresponding groups of the homozygotes. After irradiation only the groups of male and female heterozygous Gunn rats showed a decrease in the total excretion of the metabolites. Therefore blue light exposure dose not seem to influence the metabolism of tryptophan in homozygous Gunn rats.
mesh_terms: D000818:Animals; D005260:Female; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D010775:Photic Stimulation; D051381:Rats; D011911:Rats, Gunn / Q000235:genetics / Q000652:urine*; D011922:Rats, Mutant Strains / Q000652:urine*; D014364:Tryptophan / Q000652:urine*
chemical_list: D014364:Tryptophan