title: [Rubella epidemic in Piemonte in 1977: assay of specific antibodies in the umbilical cord blood and clinical follow-up (author's transl)].
abstract: Following a rubella epidemic in 1977; 1,133 samples of umbilical cord blood and 532 samples of maternal blood were assayed for specific anti-rubella haemoagglutino-inhibiting antibodies and IgM. Clinical follow-up failed to show either any increase in number of malformations and of IgM values in the malformed, or variations of mean weight and of the number of small-for-date infants. In none out of 1.031 newborns the virus was isolated from the pharynx, urine and faeces. The Authors conclude that the epidemic may have been caused by a poorly virulent virus and/or the mothers were possibly already immunized by previous infections.
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D004196:Disease Outbreaks / Q000453:epidemiology*; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007231:Infant, Newborn; D007558:Italy; D012409:Rubella / Q000151:congenital / Q000453:epidemiology*; D012412:Rubella virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M
vernacular_title: Epidemia di rosolia in Piemonte nel 1977: ricerca di anticorpi specifici nel sangue del cordone ombelicale di neonati e controllo clinico.