Reduction of feeding in rats by calcitonin.
Administration of parenteral and intracerebroventricular calcitonin resulted in suppression of stress-induced and spontaneous eating in rats. Calcitonin also reversed calcium chloride-induced eating and reduced 45Ca2+-uptake in a hypothalamic explant system. The mechanism of calcitonin-induced food suppression may be related to an alteration in calcium flux by neuronal tissue.
D000818:Animals; D001066:Appetite / Q000187:drug effects; D002116:Calcitonin / Q000494:pharmacology*; D004435:Eating / Q000187:drug effects*; D007276:Injections, Intraventricular; D051381:Rats; D011919:Rats, Inbred Strains
D002116:Calcitonin