title: Massive air embolism during cardiopulmonary bypass: successful treatment with immediate hypothermia and circulatory support.
abstract: Two patients experienced an episode of massive air embolism during extracorporeal circulation. Several emergency measures were taken. (1) The roller pump was reversed to take out air from the aorta. (2) The circuit was disconnected and recirculated to eliminate air bubbles. (3) Perfusion was restarted and the patient cooled to 24 degrees C for 40 minutes. (4) Pentothal (thiopental), steroids, and assisted ventilation were administered. The outcome was favorable in both patients, and there were no neurological sequelae. Immediate cooling and prolonged circulation seem to be a satisfactory approach to this problem.
mesh_terms: D000328:Adult; D001243:Assisted Circulation; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D004618:Embolism, Air / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D007431:Intraoperative Complications; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D012121:Respiration, Artificial; D013874:Thiopental / Q000627:therapeutic use
chemical_list: D013874:Thiopental; D008775:Methylprednisolone