Histological and meiotic evaluation of infertile men.
A meiotic analysis in a group of 90 infertile men was carried out and also histological examination. In one third of patients there were no cells in divisions and Sertoli cells were only seen in most of them. In 30% of patients the process of spermatogenesis stopped at pachytene or between the first and second meiotic division. In 38% of patients all stages of spermatogenesis and of meiosis were present. Chromosomal translocations were detected in three patients in diakinesis. The testicular biopsy is an important tool in diagnosis and management of male infertility. The histological and meiotic investigations of the testicular tissue specimen give us the information obtainable in no other way. These both investigations are essential for prognosis and treatment of infertile men.
D006801:Humans; D007248:Infertility, Male / Q000473:pathology*; D008297:Male; D008540:Meiosis; D012671:Seminiferous Tubules / Q000473:pathology; D012708:Sertoli Cells / Q000473:pathology; D013091:Spermatogenesis; D013737:Testis / Q000473:pathology* / Q000648:ultrastructure; D014178:Translocation, Genetic