[The use of fibrin tissue adhesive in parenchymal organs of the abdomen. An experimental study in rabbits and dogs (author's transl)].
In rabbits and dogs standardized lesions of the liver, kidney, and spleen were treated by application of human fibrinogen tissue adhesive. In all cases this procedure resulted in a complete control of bleeding as well as a stable and lasting closure of the wounds. During the postoperative observation time of one month, the fibrinogen tissue adhesive was initially infiltrated by leucocytes and macrophages and subsequently resorbed by a granulating tissue, characterized by the early appearance of numerous fibroblasts. Our clinical experience, until now, confirms these promising experimental results.
D000818:Animals; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D005340:Fibrinogen / Q000627:therapeutic use; D007668:Kidney / Q000601:surgery*; D008099:Liver / Q000601:surgery*; D008297:Male; D011817:Rabbits; D013154:Spleen / Q000601:surgery*; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects
D014014:Tissue Adhesives; D005337:Fibrin; D005340:Fibrinogen
Fibrinklebung an parenchymatösen Oberbauchorganen. Tierexperimentelle Untersuchungen.