title: Postcoital antifertility effect of Mentha arvensis.
abstract: A uterotonic fraction of Mentha arvensis (UM-fraction) was tested for antifertility effect in rats. Subcutaneous administration of the UM-fraction to rats pregnant from day 1 to day 10 caused a significant interruption in pregnancy. The effect was pronounced during the post-implantation period. At the effective dose, the UM-fraction did not exhibit significant estrogenic or antigonadotropic activities. However, it enhanced the estrogenic effect of estradiol when administered concurrently.
mesh_terms: D000818:Animals; D003281:Contraceptives, Postcoital; D005260:Female; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011247:Pregnancy; D011467:Prostate / Q000187:drug effects; D051381:Rats; D012669:Seminal Vesicles / Q000187:drug effects; D013737:Testis / Q000187:drug effects; D014590:Uterine Contraction / Q000187:drug effects; D014599:Uterus / Q000187:drug effects / Q000502:physiology
chemical_list: D003281:Contraceptives, Postcoital; D010936:Plant Extracts