Synthesis of 7-[7-(2-thienylacetamido)-cephalosporanamido]cephalosporanic and 6-[7-(2-thienylacetamido)cephalosporanamido]-penicillanic acids.
The synthesis of some molecules containing two moieties with potential antibiotic activity is described. These compounds were obtained by acylation of esters of 7-aminocephalosporanic and 6-aminopenicillanic acids with beta-lactam antibiotics.
D001419:Bacteria / Q000187:drug effects; D002511:Cephalosporins / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D010406:Penicillins / Q000138:chemical synthesis* / Q000494:pharmacology
D002511:Cephalosporins; D010406:Penicillins