Actin depolymerising activity in tumour-bearing rats.
The actin depolymerising activity in plasma, liver and gastrocnemius muscle of normal and tumour-bearing rats and in Walker 256 carcinoma grown in the solid and ascitic form was measured. Similar levels of actin depolymerising activity were observed in solid and ascitic forms of the tumour. No alteration in actin depolymerising activity was found to accompany the increased levels of unpolymerised actin found in the plasma and tissues of the tumour-bearing rat. It was concluded that changes in the state of polymerisation of actin in the tissues of the tumour-bearing host could not be attributed to an effect of the tumour on actin depolymerising activity.
D000199:Actins / Q000097:blood / Q000378:metabolism*; D000818:Animals; D002279:Carcinoma 256, Walker / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D000199:Actins