title: Fatal agranulocytosis attributable to cimetidine.
abstract: There exist some 12 reported cases of agranulocytosis or pancytopenia occurring after the use of cimetidine to reduce gastric acidity. Reported here is the case of a 74-year-old man with renal failure who, 21 days after treatment with cimetidine for peptic oesophagitis, developed severe granulocytopenia followed by fatal septicaemia.
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced* / Q000401:mortality; D002927:Cimetidine / Q000009:adverse effects*; D006146:Guanidines / Q000009:adverse effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D007958:Leukocyte Count; D008297:Male
chemical_list: D006146:Guanidines; D002927:Cimetidine