title: Effects of hypotonic treatment on human metaphase chromosome length.
abstract: The effects of hypotonic treatment on the structure and length of chromosomes were studied using cell cultures from human blood and skin. A strong correlation of chromosomal prolongation following treatment with solutions of increasing hypotonicity was demonstrated. This may be a suitable tool to prepare chromosomes for banding technique.
mesh_terms: D002478:Cells, Cultured; D002871:Chromosome Banding; D002877:Chromosomes, Human / Q000648:ultrastructure*; D005260:Female; D005347:Fibroblasts; D006801:Humans; D007038:Hypotonic Solutions / Q000494:pharmacology*; D008214:Lymphocytes; D008297:Male; D011189:Potassium Chloride / Q000494:pharmacology
chemical_list: D007038:Hypotonic Solutions; D011189:Potassium Chloride