Sister chromatid exchange frequencies in Progeria and Werner syndrome patients.
An analysis of the baseline and mitomycin-C-induced sister chromatid exchange (SCE) frequencies in peripheral lymphocytes derived from three patients with progeria and three Werner syndrome patients is presented. SCE frequencies did not differ significantly between the two groups of patients and their normal controls.
D000328:Adult; D001973:Bromodeoxyuridine / Q000494:pharmacology; D003434:Crossing Over, Genetic / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008677:Metaphase; D008937:Mitomycins / Q000494:pharmacology; D011371:Progeria / Q000235:genetics*; D012854:Sister Chromatid Exchange / Q000187:drug effects; D014898:Werner Syndrome / Q000235:genetics*
D008937:Mitomycins; D001973:Bromodeoxyuridine