Juvenile insulin-dependent diabetes: a possible susceptibility gene in interaction with HLA.
A model with a susceptibility gene unlinked to HLA but in interaction with this system is shown to fit the data on familial distribution in 30 multiplex families of juvenile insulin-dependent diabetes.
D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005799:Genes, Dominant; D008040:Genetic Linkage; D005838:Genotype; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008126:Lod Score; D008957:Models, Genetic; D011995:Recombination, Genetic
D006680:HLA Antigens