title: Modelling decipherment of the genetic codes.
abstract: A pocket on the complex of four nucleotides (C4N), three anticodon bases and a discriminator base, has a lock and key relation to the corresponding amino acids. This relation can explain various general features of the universal and mitochondrian genetic codes, and therefore, could be the real molecular model of the genetic code. A beautiful matching among the amino acid- C4N complex, the hypermodified base next to the third anticodon base, and the ACC chain may be the good direct evidence for the existence of the C4N, as well as other various experimental evidences, which can easily be interpreted in terms of the C4N model.
mesh_terms: D000595:Amino Acid Sequence; D000926:Anticodon; D001483:Base Sequence; D004272:DNA, Mitochondrial / Q000235:genetics; D005815:Genetic Code; D008958:Models, Molecular; D008961:Models, Structural; D009690:Nucleic Acid Conformation
chemical_list: D000926:Anticodon; D004272:DNA, Mitochondrial