Myocardial oxygen extraction rate under general anesthesia.
Myocardial oxygen extraction rates (R) were measured in dogs anesthetized with eight kinds of anesthetic agents to study the balance between myocardial oxygen consumption and its supply under general anesthesia. The R value for basal anesthesia (pentobarbital), original neuroleptanesthesia (Thalamonal), modified neuroleptanesthesia (droperidol and pentazocine), morphine anesthesia or halothane anesthesia was not significantly different from each other, and similar to those for conscious dogs reported by Merin or Spencer. On the other hand, the R values for ether anesthesia, methoxyflurane anesthesia and enflurane anesthesia were significantly lower than those for the above mentioned anesthesia.
D000768:Anesthesia, General; D000818:Animals; D003326:Coronary Circulation; D004285:Dogs; D009206:Myocardium / Q000378:metabolism*; D010101:Oxygen Consumption