A case of contact dermatitis, erythema multiforme, and toxic epidermal necrolysis.
A young adult female patient, on prolonged corticosteroid therapy for nephrotic syndrome, developed erythema multiforme and toxic epidermal necrolysis following a double exposure to a locally applied perfume. We believe that this route of exposure should be re-emphasized. Toxic epidermal necrolysis, or the scalded skin syndrome, has become a well-recognized entity which may be divided into three distinct subgroups: the staphylococcal scalded skin syndrome, nonstaphylococcal or drug-induced scalded skin syndrome, and idiopathic. We present a patient who developed a dermatitis on her chest and abdomen after using a spray cologne, which resulted in the development of erythema multiforme with progression toxic epidermal necrolysis and, ultimately, her death.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D004892:Erythema Multiforme / Q000209:etiology*; D005260:Female; D006801:Humans; D009404:Nephrotic Syndrome / Q000188:drug therapy; D010476:Perfume / Q000633:toxicity*; D013262:Stevens-Johnson Syndrome / Q000145:classification / Q000209:etiology*
D000305:Adrenal Cortex Hormones; D010476:Perfume