Transport of D-fructose and D-galactose into isolated rat hepatocytes.
Transport of D-fructose and D-galactose across the plasma membrane of isolated rat hepatocytes was followed for the net entry of sugars into sugar-free cells at 20 degrees C. Initial rates of transport showed a Michaelis-Menten dependency on sugar concentration, and transport was inhibited by 3-O-methyl-D-glucose in the external medium.
D019325:3-O-Methylglucose; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002462:Cell Membrane; D005632:Fructose / Q000378:metabolism*; D005690:Galactose / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008757:Methylglucosides / Q000494:pharmacology; D051381:Rats
D008757:Methylglucosides; D019325:3-O-Methylglucose; D005632:Fructose; D005690:Galactose