The influence of progesterone treatment on the course and outcome of pregnancies following suture of the cervix for cervical incompetence.
In this work, we have been studying the effects of Progesterone treatment on the outcome of pregnancy and its influence on the newborn, in a group of women who have undergone cerclage as a treatment of cervical insufficiency, in comparison with a group of women who have had cerclage and have not been treated with Progesterone. The results may be summarized as follows: 1) Preventive Progesterone treatment after cerclage does not influence abortion rate, but reduces significantly the hospitalization due to threatened abortion (uterine contractions). 2) In the group treated with Progesterone, lower newborn birth weight and Apgar score were observed.
D000022:Abortion, Spontaneous / Q000517:prevention & control; D000328:Adult; D001034:Apgar Score; D001724:Birth Weight; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay; D011247:Pregnancy; D011374:Progesterone / Q000627:therapeutic use*; D013537:Sutures; D002581:Uterine Cervical Incompetence / Q000628:therapy*; D014590:Uterine Contraction / Q000187:drug effects*
D011374:Progesterone