Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma.
In vitro in vivo reproterol showed intense spasmolytic effects upon the trachea and bronchi against various spasm-including agents (histamine, acetylcholine, acetyl-beta-methylcholine, 5-hydroxytryptamine, BaCl2). A comparative study with various drug used in the treatment of asthma (isoprenaline, metaproterenol, salbutamol, clenbuterol, papaverine and atropine) has been conducted.
D000818:Animals; D001249:Asthma / Q000188:drug therapy*; D001285:Atropine / Q000494:pharmacology; D001980:Bronchi; D001993:Bronchodilator Agents / Q000494:pharmacology; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D006168:Guinea Pigs; D008297:Male; D009921:Metaproterenol / Q000031:analogs & derivatives* / Q000494:pharmacology; D009132:Muscles / Q000187:drug effects*; D010208:Papaverine / Q000494:pharmacology; D013806:Theophylline / Q000031:analogs & derivatives* / Q000494:pharmacology; D014132:Trachea
D001993:Bronchodilator Agents; D004338:Drug Combinations; C014792:reproterol; D009921:Metaproterenol; D001285:Atropine; D013806:Theophylline; D010208:Papaverine