title: Volume of polycystic kidneys during reduction of renal function.
abstract: Total renal volume was measured by CT scanning in 43 patients with the adult form of polycystic kidney disease whose 24h endogenous creatinine clearance ranged from 8 to 130 ml/min. The total volume of the 2 kidneys increased from 1,212 (SD +/- 411) cm3 in patients with normal renal function to 2,053 (SD +/-698) cm3 in patients with severely decreased function, as compared to 497 (SD +/- 58) cm3 in persons without evidence of renal disease. Despite progression of the disease, the mean difference in size between the 2 kidneys remained constant and was significant only in patients with well-preserved renal function. In 23 of the 43 patients hepatic cysts and in 2 patients pancreatic cysts were demonstrable by CT scanning.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D007690:Polycystic Kidney Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed