Generalized dermal melanocytosis.
A female infant was born with generalized blue-gray discoloration of the skin. Light microscopy demonstrated the diffuse distribution of dihydroxyphenylalanine-positive, dermal melanocytes. Electron microscopy confirmed the identification of the pigment-bearing cells as melanocytes and demonstrated individual melanocytes to be invested with a filamentous extracellular sheath. To our knowledge, comparable, generalized, dermal melanocytosis has not previously been reported in a newborn.
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008544:Melanocytes / Q000473:pathology; D010859:Pigmentation Disorders / Q000151:congenital* / Q000473:pathology; D012867:Skin / Q000473:pathology