Synthesis and pharmacological evaluation of some 2,3-dihydro-3-phenyl-1,4-benzodioxin derivatives.
The synthesis and some pharmacological properties of five 2,3-dihydro-3-phenyl-1,4-behzodioxin derivatives (II d-h) are reported. The new compounds generally result more active as local anaesthetics, but less effective as anti-arrhythmic agents than the corresponding 1,3-benzodioxole derivatives.
D000779:Anesthetics, Local / Q000138:chemical synthesis*; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis*; D004147:Dioxins / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice
D000779:Anesthetics, Local; D000889:Anti-Arrhythmia Agents; D004147:Dioxins