[Recurrent meningococcal meningitis associated with complement C6 deficiency (author's transl)].
In a young West-Indian woman recurrent meningococcal meningitis was found to be associated with hereditary deficiency of the C6 component of complement. Such an association has already been reported in 8 patients, all black. Measuring the total haemolytic complement would provide an easy way of detecting high risk subjects, who would benefit from immunization.
D000328:Adult; D044383:Black People; D001770:Blood Bactericidal Activity; D003183:Complement C6 / Q000172:deficiency* / Q000235:genetics; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D008585:Meningitis, Meningococcal / Q000235:genetics / Q000276:immunology* / Q000517:prevention & control; D008875:Middle Aged; D012008:Recurrence
D003183:Complement C6; D003165:Complement System Proteins
Méningite à méningocoques récidivante associée à un déficit en 6e composant du complément.