Renal involvement in Gaucher's disease.
A patient with chronic Gaucher's disease is described who developed glomerulopathy 24 years after splenectomy terminating in renal failure. The pathological changes of this very rare complication of Gaucher's disease are described. The few similar cases reported in the literature are reviewed and the possible pathogenetic pathways discussed.
D005260:Female; D005776:Gaucher Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D013997:Time Factors