[Cytofluorimetric study of small, intensely fluorescing cells in the atria of rats following a single injection of guanethidine].
The fluorescence intensity of small high-fluorescent (SHF) cells of rat auricles was measured after the treatment by the modified Falk method in health and 3,14 and 72 hours after a single injection of guanethidine. No significant changes in the fluorescence intensity were found on analysis of the entire pool of SHF auricular cells and of individual SHF cells, while SHF cells of the clasters of the superior caval vein and interauricular septum manifest counterphasic deviations from the basal line of fluorescence, with these deviations being most remarkable 14 hours after the injection. The changes in the fluorescence intensity of SHF cells, which were seen within the periods of time corresponding with the minimum noradrenaline content in the heart allow the conclusion that SHF cell function is in good agreement with the heart noradrenaline level. The line of changes in the catecholamine content of SHF cells in the areas under consideration is likely to attest to the regional principle of the SHF cell pool organization in auricular tissue.
D000818:Animals; D005453:Fluorescence; D006145:Guanethidine / Q000494:pharmacology*; D006346:Heart Septum / Q000166:cytology; D008297:Male; D009206:Myocardium / Q000032:analysis / Q000166:cytology*; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D014683:Vena Cava, Superior / Q000166:cytology
D009638:Norepinephrine; D006145:Guanethidine
Tsitofliuorimetricheskoe issledovanie melkikh, intensivno fliuorestsiruiushchikh kletok predserdiĭ krys posle odnokratnoĭ in"ektsii guanetidina.