[Juvenile and familial amyotrophic lateral sclerosis. 2 case reports (author's transl)].
The case report of two brothers who evidenced neurological disorders with peripheral nerve syndrome, pyramidal deficit and bulbar symptoms is described. The diagnosis of amyotrophic lateral sclerosis was assumed upon the association of these clinical features. Seven and nine years respectively after the beginning of the disease, an increase of the clinical features was noticed in the 2 children, more pronounced in the second one. The possibility of true juvenile and familial amyotrophic lateral sclerosis is discussed in this study; different aspects of this disease are described. A final classification of these 2 cases will not be possible until histological features are available.
D000690:Amyotrophic Lateral Sclerosis / Q000145:classification / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008297:Male; D013997:Time Factors
La sclérose latérale amyotrophique juvénile et familiale. Place nosologique, á propos de deux observations.