[Preparation of eye drops with zinc sulphate and adrenaline (author's transl)].
The preparation of stable composed eye drops with epinephrine, zinc sulfate and procaine was studied. It was proved that the preparation using Adrenalnum solutum Spofa does not guarantee sufficient stability. It follows from the results that the stability of eye drops can be prolonged from 2 or 3 d to 1 month by the addition of 0.05% L-cysteine, N-acetylcysteine and sodium metabisulfite respectively.
D000111:Acetylcysteine; D002626:Chemistry, Pharmaceutical; D003545:Cysteine; D004339:Drug Compounding; D004355:Drug Stability; D004837:Epinephrine / Q000008:administration & dosage*; D009883:Ophthalmic Solutions; D013431:Sulfates / Q000008:administration & dosage*; D013447:Sulfites; D013997:Time Factors; D015032:Zinc / Q000008:administration & dosage*; D019287:Zinc Sulfate
D009883:Ophthalmic Solutions; D013431:Sulfates; D013447:Sulfites; C005200:sodium metabisulfite; D019287:Zinc Sulfate; D015032:Zinc; D003545:Cysteine; D000111:Acetylcysteine; D004837:Epinephrine
Herstellung von Augentropfen mit Zinksulfat und Adrenalin.