Malakoplakia of the larynx.
The first case of malakoplakia of the larynx in the world literature is reported. The soft raised plaques were removed from a 61-year-old white male, who was a heavy smoker and complained of hoarseness, but was otherwise in good general condition. From the follow-up of our patient, it is concluded that malakoplakia is not of particularly bad prognosis when affecting the larynx, and that simple local excision seems to be enough to produce cure. On these grounds, the laryngologists should be aware of the entity and consider it when dealing with raised nodules or plaques in the larynx, while the pathologists should be alert to look for the Michaelis-Gutman bodies, when encountered with peculiar histiocytic reactions anywhere in the body, even in the larynx.
D006685:Hoarseness / Q000209:etiology; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications / Q000473:pathology*; D008287:Malacoplakia / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012907:Smoking