title: [Course of enzymopenic hemolytic anemia (glutathione reductase deficiency) simulating chronic polyarthritis].
abstract: Enzymopenic haemolytic anaemias are rare diseases in which there is an excess iron turnover. The iron is mainly deposited in many tissues giving rise to fibrosis and tissue damage. There is always a specific arthropathy; by involving a number of joints at the same time the clinical picture may resemble active rheumatoid arthritis, and therefore an erroneous treatment with gold, chloroquine, D-penicillamine or corticosteroids is possible. The diagnostic procedure in a patient suffering from enzymopenic haemolytic anaemia and pathogenetic mechanisms are discussed.
mesh_terms: D000743:Anemia, Hemolytic / Q000175:diagnosis* / Q000201:enzymology; D000745:Anemia, Hemolytic, Congenital / Q000175:diagnosis* / Q000201:enzymology; D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005980:Glutathione Reductase / Q000172:deficiency*; D006801:Humans; D007501:Iron / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D007501:Iron; D005980:Glutathione Reductase
vernacular_title: Verlauf einer enzymopenischen, hämolytischen Anämie (Glutathionereductase-mangel) unter dem Bild einer "chronischen Polyarthritis".