[Changes in vessels of the microcirculatory bed following parenteral administration of xenogeneic cerebrospinal fluid obtained in vivo to normal animals and animals with experimental hypercholesterolemia].
Effect of parenteral administration of xenogenic liquor, vitally obtained, on the state of the microcirculatory bed, as well as its biostimulating action for cellular metabolism activation have been studied. The number of actively functioning capillaries increases, microvessels dilate, vascular permeability intensifies not only under normal conditions, but under experimental hypercholesteremia, as well. How the changes observed in the microcirculatory bed depend on various doses and total amount of the preparation administered, as well as means of its conservation have been analysed and stated. The dynamics of indices on lipid metabolism have been studied.
D000818:Animals; D002199:Capillary Permeability; D002555:Cerebrospinal Fluid; D002784:Cholesterol / Q000097:blood; D006937:Hypercholesterolemia / Q000473:pathology / Q000628:therapy*; D008055:Lipids / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008833:Microcirculation / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D011817:Rabbits; D051381:Rats
D008055:Lipids; D008077:Lipoproteins, LDL; D002784:Cholesterol
Izmeneniia sosudov mikrotsirkuliatornogo rusla pri parenteral'nom vvedenii prizhiznenno poluchennoĭ ksenogennoĭ spinnomozgovoĭ zhidkosti v usloviiakh normy i pri éksperimental'nom giperkholesterinemii.