[Pure red cell aplasia and chronic leukemia. Usefulness of ferrokinetic measurements (author's transl)].
Erythroblastopenia is probably not rare in chronic lymphocytic leukemia (CLL) but the diagnosis could be difficult. It produces a severe and rapidly developing anemia, without evidence of hemolysis. The chief differential diagnosis is the common bone marrow insufficiency of end-stage CLL. Iron kinetics measurements are typical, showing a total erythropoietic insufficiency, and a red cell utilization of radio-iron that is practically zero. Erythroblastopenia could be cured with corticosteroid or sometimes with immunosuppressive treatment.
D000328:Adult; D000741:Anemia, Aplastic / Q000175:diagnosis / Q000209:etiology*; D004900:Erythroblasts; D004912:Erythrocytes; D005260:Female; D006801:Humans; D007504:Iron Radioisotopes; D007700:Kinetics; D007945:Leukemia, Lymphoid / Q000150:complications*; D008297:Male; D008875:Middle Aged
D007504:Iron Radioisotopes
Les érythroblastopénies de la leucémie lymphoïde chronique. Intérêt de la cinétique du radiofer.