The measurement of clonidine in human plasma and urine by combined gas chromatography mass spectrometry with ammonia chemical ionization.
The dimethyl derivatives of clonidine and [2H4]clonidine give good chemical ionization mass spectra when ammonia is used as reagent gas. A gas chromatographic mass spectrometric selected ion monitoring assay for the estimation of clonidine in plasma and urine using ammonia chemical ionization is described.
D003000:Clonidine / Q000097:blood* / Q000652:urine; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D012016:Reference Values
D003000:Clonidine