[Comparison of the antibacterial effects of gentamycin, tobramycin, dibekacin and amikacin in urinary germs].
We isolated 491 pathogens of urinary tract infections of our urological in-patients. Sensitivity against gentamycin, tobramycin, dibekacin and amikacin was tested in vitro. Our data were compared with the statements of the medical literature. It should be pointed out the great fraction of grampositive staphylococci. Their sensitivity rate of 40% against the tested aminoglycosides was remarkably small. Enterococci had a sensitivity rate of 70% against gentamycin, tobramycin and dibekacin. Their sensitivity rate against amikacin was only 20% as expected, because enterococci do not belong to the proper antibiotic spectrum. The four aminoglycosides are highly effective against gramnegative organisms with with no appreciable differences.
D000583:Amikacin / Q000494:pharmacology; D000617:Aminoglycosides / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004755:Enterobacteriaceae / Q000187:drug effects; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects; D014031:Tobramycin / Q000494:pharmacology
D000617:Aminoglycosides; D005839:Gentamicins; D000583:Amikacin; D014031:Tobramycin
Vergleich der antibakteriellen Wirksamkeit von Gentamycin, Tobramycin, Dibekacin und Amikacin bei Harnkeimen.