Erythrocyte catechol-O-methyltransferase activity in a Swedish population.
Erythrocyte catechol-O-methyltransferase (COMT) activity has been analyzed in 185 individuals. The activities showed a trimodal frequency distribution. This suggests an autosomal codominant inheritance of the human erythrocyte COMT activity. The mean male COMT activity was 18.9 +/- 7.0 (S.D.) nmol/ml RBC/h. The mean female activity was 16.1 +/- 6.3 nmol/ml RBC/h and the frequency distribution pattern for women was shifted towards lower values.
D000328:Adult; D002394:Catechol O-Methyltransferase / Q000097:blood* / Q000235:genetics; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008875:Middle Aged; D013548:Sweden
D002394:Catechol O-Methyltransferase