Incorporation in vivo of radioisotopic precursors into seromucoid proteins in streptozotocin diabetic rats.
In vivo incorporations of (14)C-leucine and (3)H-galactose into the seromucoid proteins are decreased in streptozotocin diabetic rats. The decrease in galactose incorporation is greater than that of leucine, and suggests that streptozotocin diabetes influences the metabolism of both the protein and sugar moieties of seromucoid glycoproteins.
D000818:Animals; D002250:Carbon Radioisotopes; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005690:Galactose / Q000378:metabolism*; D007700:Kinetics; D007930:Leucine / Q000378:metabolism*; D008297:Male; D009961:Orosomucoid / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
D002250:Carbon Radioisotopes; D009961:Orosomucoid; D014316:Tritium; D007930:Leucine; D005690:Galactose