Primordial transport of sugars and amino acids via Schiff bases.
Experimental support is given for a model concerning the origin of a primordial transport system. The model is based on the facilitated diffusion of amino acids stimulated by aliphatic aldehyde carriers and sugars stimulated by aliphatic amine carriers. The lipid-soluble diffusing species is the Schiff base. The possible role of this simple transport system in the origin of an early protocell is discussed.
D000596:Amino Acids / Q000378:metabolism*; D005075:Biological Evolution; D001692:Biological Transport; D050260:Carbohydrate Metabolism; D004058:Diffusion; D005947:Glucose / Q000378:metabolism; D007700:Kinetics; D008051:Lipid Bilayers / Q000378:metabolism; D050356:Lipid Metabolism; D008954:Models, Biological; D012545:Schiff Bases / Q000378:metabolism*; D012995:Solubility
D000596:Amino Acids; D008051:Lipid Bilayers; D012545:Schiff Bases; D005947:Glucose