Studies on human Laryngeal papilloma. Degeneration of lymphocytes within the neoplastic cells.
Biopsies from 5 cases of Juvenile Laryngeal Papilloma were studied by electron microscopy. In 2 cases, phagocytosed neutrophils were seen in various stages of degeneration and disintegration within the neoplastic cells. The possible phenomenon of "emperiopolesis' and "phagocytosis' in a benign neoplasm is described, and it is suggested that all cases of Juvenile Laryngeal Papilloma must be carefully examined by light- and electron microscopy in an attempt to locate any phagocytic activity in the neoplastic cells which may provide evidence for the early detection of malignancy.
D001706:Biopsy; D002648:Child; D006801:Humans; D007822:Laryngeal Neoplasms / Q000648:ultrastructure*; D007830:Larynx / Q000473:pathology; D008854:Microscopy, Electron; D009504:Neutrophils / Q000648:ultrastructure*; D010212:Papilloma / Q000648:ultrastructure*; D010587:Phagocytosis