Rapid thin-layer chromatography of various weak analgesics in saliva.
A thin-layer chromatographic method was developed to analyze phenacetin, 4-amino-phenazone and N-methyl-4-aminophenazone (5 and 1.25 micrograms/ml); bucetin (4-ethoxy-beta-hydroxybutyranilide), propyphenazone and N-acetyl-4-aminophenazone (2.5 and 1.25 micrograms/ml); phenazone (15 and 1.25 micrograms/ml); and N-acetylsalicylamide (0.25 micrograms/ml). The method was designed to study the bioavailability of different commercial tablets from salivary concentration data.
D000700:Analgesics / Q000032:analysis*; D000983:Antipyrine / Q000032:analysis; D002855:Chromatography, Thin Layer; D006801:Humans; D010615:Phenacetin / Q000032:analysis; D012463:Saliva / Q000032:analysis*
D000700:Analgesics; D010615:Phenacetin; D000983:Antipyrine