title: Biochemical genetics of Fundulus heteroclitus (L.). IV. Spatial variation in gene frequencies of Idh-A, Idh-B, 6-Pgdh-A, and Est-S.
abstract: The spatial variation in gene frequencies of four unlinked polymorphic loci was studied in the teleost Fundulus heteroclitus. Three loci (Idh-A, Idh-B, and Est-S) exhibit significant north-south clinal variation in allelic frequencies along the Atlantic Coast of North America, while a fourth locus (6-Pgdh-A) shows a modest clinal variation. These data, together with our previous data for Ldh-B, Mdh-A, Gpi-B, and Pgm-A, reveal a pattern of low gene diversity in the colder northern extremes of the species range and high gene diversity in warmer southern latitudes.
mesh_terms: D000483:Alleles; D000818:Animals; D002980:Climate; D004950:Esterases / Q000097:blood / Q000235:genetics*; D005399:Fishes / Q000235:genetics*; D005787:Gene Frequency; D008040:Genetic Linkage; D014644:Genetic Variation; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D007527:Isoenzymes / Q000235:genetics*; D007695:Killifishes / Q000235:genetics*; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics*; D011110:Polymorphism, Genetic
chemical_list: D007527:Isoenzymes; D007521:Isocitrate Dehydrogenase; D010734:Phosphogluconate Dehydrogenase; D004950:Esterases