Perioperative heparin prophylaxis of deep venous thrombosis in patients with peripheral vascular disease.
Perioperative low dose heparin was administered to 24 patients who were compared with 19 control patients undergoing peripheral vascular surgical procedures. This prophylactic measure was ineffective in reducing the incidence of subclinical, postoperative deep venous thrombosis, as indicated by iodine-125 fibrinogen scanning. The data suggest that patients undergoing vascular surgery will not benefit from the routine application of this prophylactic regimen.
D005340:Fibrinogen; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D007457:Iodine Radioisotopes; D007866:Leg / Q000098:blood supply*; D011183:Postoperative Complications / Q000517:prevention & control; D011446:Prospective Studies; D011897:Random Allocation; D013924:Thrombophlebitis / Q000175:diagnosis / Q000517:prevention & control*; D014656:Vascular Surgical Procedures
D007457:Iodine Radioisotopes; D005340:Fibrinogen; D006493:Heparin