title: Cryotherapy in the treatment of cervical intraepithelial neoplasia.
abstract: Cryotherapy was used to treat 516 patients with various degrees of dysplasia and carcinoma in situ over a 7-year period. Seventy-one percent of patients had either severe dysplasia or carcinoma in situ. In 88% of the patients treated, a single treatment session was successful in eradicating the lesion. Treatment was defined as successful when cytologic and colposcopic findings were negative 1 year after treatment. Five percent of patients were lost to follow-up. The criteria for selection of patients and possible causes of treatment failure are discussed.
mesh_terms: D000328:Adult; D001706:Biopsy; D002278:Carcinoma in Situ / Q000628:therapy; D003127:Colposcopy; D003452:Cryosurgery; D005260:Female; D006801:Humans; D002578:Uterine Cervical Dysplasia / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*