Orogenital ulcers, SLE and hydralazine.
The case is reported of a man developing drug-induced systemic lupus erythematosus while taking hydralazine. The illness was characterized by arthritis and a purpuric rash particularly in the light-sensitive areas as well as orogenital and cutaneous ulceration. Anti-nuclear antibody and DNA binding were positive. All clinical manifestations disappeared on withdrawal of hydralazine.
D006801:Humans; D006830:Hydralazine / Q000009:adverse effects* / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced*; D010409:Penile Diseases / Q000139:chemically induced*; D012883:Skin Ulcer / Q000139:chemically induced; D014456:Ulcer / Q000139:chemically induced
D006830:Hydralazine