Estimation of P50 from a single venous blood sample.
The oxygen tension at 50% saturation of haemoglobin, or P50 was calculated from a single O2 tension and saturation measurement on a venous blood sample by means of the proportional displacement assumption of Severinghaus and a parallel displacement assumption. These calculations were compared with a two-point technique, based on Hill's formula, which was assumed to be accurate. The results obtained from the simpler, one-point techniques correlated well with the more complex two-point estimation. This correlation remained for subjects with normal, high, and low P50.
D000740:Anemia / Q000097:blood; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000097:blood; D008297:Male; D008433:Mathematics; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000378:metabolism*; D014680:Veins
D010108:Oxyhemoglobins; D010100:Oxygen