Effect of homogeneous magnetic fields on responses to toxic stimulation in Spirostomum ambiguum.
Effects of DC magnetic fields, up to 125,000 G, on the survival of the ciliated protozoan Spirostomum ambiguum exposed to the toxic substance 2,2'-dipyridyldisulfide are reported. The magentic field diminishes the ability of the organism to survive the drug, and lengthens the extension phase of the contraction cycle. It is proposed that the magnetic field alters the regulation of intracellular (Ca2+) transients.
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000494:pharmacology*; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D004220:Disulfides / Q000494:pharmacology*; D056890:Eukaryota / Q000187:drug effects / Q000502:physiology*; D007700:Kinetics; D008280:Magnetics; D011725:Pyridines / Q000494:pharmacology*; D013439:Sulfhydryl Reagents / Q000494:pharmacology*
D004220:Disulfides; D011725:Pyridines; D013439:Sulfhydryl Reagents; C001105:2,2'-dipyridyl disulfide; D015082:2,2'-Dipyridyl