The effect of lentinan on pregnancy of the New Zealand white rabbit.
Lentinan at 0.1, 0.3 and 1.0 mg/kg/day was administered i.v. to the New Zealand White rabbit, once daily, on days 6--18 of gestation. There were no significant treatment-related effects of post implantation loss, mean litter size and weight, mean foetal weight or the incidence of minor skeletal or visceral anomalies.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D005333:Fetus / Q000187:drug effects; D007912:Lentinan / Q000633:toxicity*; D011134:Polysaccharides / Q000633:toxicity*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D011817:Rabbits; D013154:Spleen / Q000187:drug effects
D011134:Polysaccharides; D007912:Lentinan