title: Evolution of the Hong Kong influenza A sub-type. Structural relationships between the haemagglutinin from A/duck/Ukraine/1/63 (Hav 7) and the Hong Kong (H3) haemagglutinins.
abstract: The relationship between the haemagglutinin from the influenza virus A/duck/Ukraine/1/63 (Hav 7) and the human Hong Kong variants (H3) has been investigated. Amino-acid-sequence analysis shows that the Hav 7 haemagglutinin closely resembles the 1968 human H3 haemagglutinin in structure. However, the number of amino-acid-sequence differences (23) suggest that the Hong Kong haemagglutinin gene did not come directly from A/duck/Ukraine/1/63 but from a virus derived from it by antigenic drift during the period 1963-1968.
mesh_terms: D000595:Amino Acid Sequence; D005787:Gene Frequency; D006389:Hemagglutinins, Viral / Q000235:genetics; D009980:Influenza A virus / Q000032:analysis* / Q000235:genetics; D009844:Oligosaccharides / Q000032:analysis
chemical_list: D006389:Hemagglutinins, Viral; D009844:Oligosaccharides