title: Epithelial invasion and secretion of banded collagen in the regenerating lens capsule of the rat.
abstract: The invasion of large areas of the anterior lens capsule by epithelial cells occurs during regeneration of this basement membrane, in the 3 to 4 months after the capsule has been thinned by collagenase enzyme. The regenerated capsule in these areas is grossly abnormal; it contains up to 15 alternating layers of banded collagen and apparently normal capsular material. The epithelial cells within the laminated capsule, which may secrete the banded collagen, are fibroblast-like and may migrate from the lens epithelium. Banded collagen in the lens capsule has a much smaller periodicity (approximately 5.3nm) than that found in other parts of the eye and may be composed of the same type of filament as normal lens capsule.
mesh_terms: D000818:Animals; D003094:Collagen / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism / Q000502:physiology; D007908:Lens, Crystalline / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D051381:Rats; D012038:Regeneration
chemical_list: D003094:Collagen