Deformation of transforming red cells in various pH solutions.
Centrifugation into a rapid cell fixative is used to determine the conformation of red cells at various pH-values as a measure of red cell deformability. Discocytes show a good deformation into handbag-like forms; echinocytes and stomatocytes have reduced deformability with characteristic shapes of deformation.
D002021:Buffers; D002498:Centrifugation; D004910:Erythrocyte Membrane / Q000502:physiology*; D004912:Erythrocytes / Q000166:cytology* / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration
D002021:Buffers