Granulomatous inflammatory reaction to degenerating Desçemet's membrane.
Granulomatous inflammatory reaction to degenerating Desçemet's membrane was found in histopathologic study of a keratoplasty specimen from a case of disciform keratitis following childhood varicella infection. The histologic findings suggest acquired autosensitivity to degenerating Desçemet's membrane as a likely cause for the chronic keratitis. Such a reaction may persist for many years in a corneal leukoma that, clinically, appears free of inflammation.
D000293:Adolescent; D002908:Chronic Disease; D003886:Descemet Membrane / Q000276:immunology / Q000473:pathology*; D006084:Graft Rejection; D006801:Humans; D007634:Keratitis / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D008297:Male