Antidepressants inhibit enkephalin binding to synaptosome-enriched fractions of rat brain.
D000639:Amitriptyline / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D002997:Clomipramine / Q000494:pharmacology; D003891:Desipramine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004723:Endorphins / Q000378:metabolism*; D004744:Enkephalin, Methionine; D004745:Enkephalins / Q000378:metabolism*; D007099:Imipramine / Q000494:pharmacology; D008297:Male; D009661:Nortriptyline / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013574:Synaptosomes / Q000378:metabolism; D014745:Viloxazine / Q000494:pharmacology
D000928:Antidepressive Agents; D004723:Endorphins; D004745:Enkephalins; D000639:Amitriptyline; D004744:Enkephalin, Methionine; D014745:Viloxazine; D009661:Nortriptyline; D002997:Clomipramine; D007099:Imipramine; D003891:Desipramine