Case report. Atypical findings in adrenoleukodystrophy.
Computed tomography (CT) in a child with typical clinical and biochemical features of adrenoleukodystrophy (ALD) revealed striking pathologic enhancement in the centra semiovalia, posterior corpus callosum, and corticospinal tracts within the internal capsules, cerebral peduncles, and basis pontis. Central calcifications were detected within otherwise typical symmetrical low attenuation lesions in the periatrial white matter. These findings further expand the spectrum of CT abnormalities in ALD and may represent a link between the recently described Type 1 and Type 11 CT patterns.
D000311:Adrenal Glands / Q000473:pathology; D000309:Adrenal Insufficiency / Q000150:complications; D001921:Brain / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging; D002675:Child, Preschool; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000000981:diagnostic imaging*; D006801:Humans; D006965:Hyperplasia; D008297:Male; D014057:Tomography, X-Ray Computed