[Duodenal ulcer. Randomized study with 8 therapeutic schedules].
In the outpatient management of 112 patients with duodenal ulcer, 8 therapeutic regimens were tested, consisting of a combination of a one or more of 3 drugs, and compared with placebo. Regarding the tested drugs (anticholinergics, sulphoglicopeptide and sucralfate) in a randomized fashion for 30 months, no regimen was statistically better than placebo, neither in combination (44,6% in 60 days), nor the more effective regimen (64,2%: anticholinergic plus sucralfate). The placebo group had 42,8% of healing rate.
D000328:Adult; D000368:Aged; D000863:Antacids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D006020:Glycopeptides / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D012959:Socioeconomic Factors
D000863:Antacids; D006020:Glycopeptides; D010276:Parasympatholytics
Ulcera duodenal. Estudo randomizado, com 8 esquemas terapêuticos.