title: Alkylating activity of processed fish products treated with sodium nitrite in simulated gastric juice.
abstract: The alkylating activity of extracts from several fish products with or without sodium nitrite in simulated gastric juice has been investigated. Some of the extracts had strong alkylating potency which may be due to the action of the formed N-nitrosamides. These compounds were not derived from nitrosation of methylguanidine and agmatine or from pyrolysis products of the processed fish. The results suggest an urgent need for a comprehensive investigation of nitrosation of various foods in simulated gastric juice.
mesh_terms: D000477:Alkylating Agents / Q000378:metabolism*; D000818:Animals; D005396:Fish Products; D005511:Food Handling; D005750:Gastric Juice / Q000378:metabolism*; D006358:Hot Temperature; D009573:Nitrites / Q000378:metabolism*; D012977:Sodium Nitrite / Q000378:metabolism*; D013274:Stomach Neoplasms / Q000209:etiology
chemical_list: D000477:Alkylating Agents; D009573:Nitrites; D012977:Sodium Nitrite