Succinimides with oxyacetate side chain as potential anticonvulsant agents.
Two new compounds, ethyl N-succinimidoxyacetate and methyl N-succinimidoxyacetate, were prepared by reacting a solution of freshly recrystallized N-hydroxysuccinimide in tetrahydrofuran with a mixture of the corresponding halogenated ester and triethylamine. The compounds possessed some anticonvulsant properties.
D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis*; D002645:Chickens; D013388:Succinimides / Q000138:chemical synthesis* / Q000494:pharmacology
D000927:Anticonvulsants; D013388:Succinimides; C032990:methyl N-succinimidoxyacetate; C032989:ethyl N-succinimidoxyacetate