"T's and B's"-Midwestern heroin substitute.
"T's and B's" is the street name for the combination of pentazocine and tripelennamine. This combination of drugs has emerged as a major intravenous substitute for heroin in recent years, especially in the Midwest. 104 cases involving 82 patients over a 9-month period were seen at St. Elizabeth Medical Center in Dayton, Ohio. Abscesses and cellulitis were seen in 39% of cases. A characteristic drug reaction involved 38% of cases, and consisted of chest pain, agitation, anxiety, muscle spasms, dizziness, diaphoresis, and nausea as well as other symptoms. Seizures, syncope, and near-syncope were seen in 15% of cases, and a previously described pulmonary reaction involved 38% of cases, and consisted of chest pain syndrome was seen in 4% of the cases.
D000293:Adolescent; D000328:Adult; D004338:Drug Combinations; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D010423:Pentazocine / Q000506:poisoning*; D014309:Tripelennamine / Q000506:poisoning*
D004338:Drug Combinations; D013287:Illicit Drugs; D014309:Tripelennamine; D010423:Pentazocine