title: A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects.
abstract: A noncontact tonometer was used to demonstrate in normal human volunteers the ocular hypotensive effects of single instillations of pindolol (1%) and timolol (0.25 and 0.5%) eye drops. Falls in intraocular pressure were significantly correlated with resting intraocular pressure. Evidence of systemic cardiovascular effects was seen in reductions in resting heart rate.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D010869:Pindolol / Q000008:administration & dosage / Q000494:pharmacology*; D011412:Propanolamines / Q000494:pharmacology*; D011674:Pulse / Q000187:drug effects; D013999:Timolol / Q000008:administration & dosage / Q000494:pharmacology*; D014065:Tonometry, Ocular / Q000379:methods
chemical_list: D011412:Propanolamines; D013999:Timolol; D010869:Pindolol