Fourier-analysis of peristaltic pressure variations in the oesophagus during a 12-hour investigation. A study in normal subjects.
Long-term measurements have been made of peristaltic pressure variations 8 and 23 cm proximally to the gastro-oesophageal sphincter. The investigation was performed using perfused catheter systems and results of the 12-h measuring period were recorded on tape recorder. The peristaltic pressure variations were frequency analysed using a Fast Fourier Transform analyser. Nineteen normal subjects took part in the study. One subject was tested seven times. The investigation showed that the significant information regarding the pressure variations can be registered by recording systems with an upper frequency limit of at least 2 Hz. The pressure variations were built up more rapidly proximally in the organ than distally. Repeated investigations on a single subject showed that the intravariation lies within the intervariation in the subjects tested.
D000328:Adult; D004943:Esophagogastric Junction / Q000502:physiology; D004947:Esophagus / Q000502:physiology*; D005260:Female; D005583:Fourier Analysis; D005764:Gastroesophageal Reflux / Q000503:physiopathology; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D010528:Peristalsis; D011312:Pressure; D013997:Time Factors; D014160:Transducers, Pressure