Chemical screening of radiation protecting agents.
An aqueous solution of 2-propanol was chosen as chemical system for fundamental study of the chemical screening of organic compounds on the responsibility for ionizing radiation. The effect of additives on the yield of acetone was investigated by subjecting this system on gamma-radiolysis. The results show that this system is suitable for the estimation of radiation protecting character of the known radiation protecting agents and compounds which act as a OH scavenger. On the basis of these results, various nitrogen-containing additives having free amino group, guanidine group and hetero-cyclic amine were examined first of all in expectation of improvement for the toxicity of sulfur-containing compounds.
D000433:1-Propanol / Q000528:radiation effects*; D000096:Acetone / Q000032:analysis; D000588:Amines; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005720:Gamma Rays; D011837:Radiation-Protective Agents
D000588:Amines; D011837:Radiation-Protective Agents; D000096:Acetone; D000433:1-Propanol