[Does the fibrin glue accelerate the healing of tendons? (author's transl)].
The question of an accelerating influence of the fibrin adhesive (Immuno AG, Vienna) on healing has been investigated in the suture of heel tendons of 69 rabbits. The achilles-tendon cut through was anastomosed in typical way, but besides in the one group a homologous fibrinogen-cryoprecipitate was applied. The histological and biomechanical evaluations of the anastomosis were carried out after one, two and four weeks. By means of the fibrin adhesive the loading capacity of the healing tendons could not be accelerated. The data of rupture stress were in the control group after one week 1.65 kg (+/- 1.14) and after two weeks 8.66 kg (+/- 1.38) and in the fibrin group 2.13 kg (+/-1.28) respectively 7.76 kg (+/-2.19). The difference between the two groups is not significant. Four weeks postoperatively the test could not be carried out, for the anchorage of the tendons at the material testing machine was not possible for over 15 kg stress-strain. Histologically a distinct difference of the repair process of the tendons operated on could not be seen in the two groups either.
D000125:Achilles Tendon / Q000503:physiopathology / Q000601:surgery*; D000818:Animals; D001696:Biomechanical Phenomena; D005337:Fibrin / Q000627:therapeutic use*; D011817:Rabbits; D014014:Tissue Adhesives; D014945:Wound Healing / Q000187:drug effects*
D014014:Tissue Adhesives; D005337:Fibrin
Beschleunigt das Fibrinklebesystem (FKS) die Heilungsvorgänge von Sehnengewebe?