Symmetrical fibro-osseous dysplasia of rib--post-traumatic dysplasia?
We describe two patients with a distinctive histological condition which clinically and radiologically mimics fibrous dysplasia of the rib. Both patients presented with chronic pain confined to one rib. In each case their radiographs showed a solitary, fusiform expansion of a rib with variable calcification. Histologically the lesions were characterized by a central core of xanthomatous macrophages surrounded by cancellous bone that showed symmetrical and progressive maturation centrifugally towards the cortex, a pattern which distinguishes these lesions from the irregular pattern of fibrous dysplasia.
D000368:Aged; D001847:Bone Diseases / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis* / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012272:Ribs / Q000293:injuries* / Q000473:pathology