title: [Myocardial pathomorphology in exotoxic shock].
abstract: Morphological, including electron microscopic, examinations of the hearts from 49 patients dying in the stage of shock after acute poisoning revealed general structural alterations in the myocardium typical of shock of any etiology as well as some specific features of the heart involvement related to the kinds of toxicity. The general alterations include damage of microcirculation vessels, rheological blood disorders, interstitial edema, leading to disorders in cardiomyocyte metabolism and development in some of them of dystrophic and necrotic lesions. In acetic acid poisoning, fatty degeneration of cardiomyocytes is more marked; dichlorethane poisoning is characterized by contractural lesions, and that with cardiotoxic substances by diffuse edema of sarcoplasm with "disconnected" organelles.
mesh_terms: D001344:Autopsy; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D009206:Myocardium / Q000201:enzymology / Q000473:pathology*; D011041:Poisoning / Q000201:enzymology / Q000473:pathology*; D012769:Shock / Q000201:enzymology / Q000473:pathology*
vernacular_title: Patomorfologiia miokarda pri ékzotoksicheskom shoke.