Arrest reaction with concomitant spike and wave afterdischarge following thalamic stimulation in conscious juvenile monkeys with Al (OH)3 focal premotor lesions.
The behavioural and electroencephalographic responses resulting from stimulation of a specific area in the nucleus medialis dorsalis (nMD) of unanaesthetized juvenile Rhesus monkeys is described. A behavioural arrest reaction, lack of awareness and motor inhibition with concomitant 2 1/2 to 3Hz spike and wave EEG afterdischarge patterns were obtained by stimulation of the nMD in monkeys with bilaterally symmetrical aluminium hydroxide Al (OH)3 lesions in anterior premotor cortical areas.
D000536:Aluminum Hydroxide / Q000633:toxicity*; D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology; D004558:Electric Stimulation; D004562:Electrocardiography; D004569:Electroencephalography; D004585:Electrooculography; D008253:Macaca mulatta; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D013787:Thalamic Nuclei / Q000502:physiology; D013788:Thalamus / Q000502:physiology*
D000536:Aluminum Hydroxide