title: [Investigation of anomalous growth of heart refractoriness during tachycardia].
abstract: Action potential (AP) characteristics during anomalous growth of refractoriness (R) in rabbit atrium were investigated. Anomalous growth of R arises under the stimulation frequency more than 4-5 s-1. Anomalous R growth is accompanied by AP duration, amplitude and upstroke velocity decrease. These results are in a good agreement with the theoretical model (Pertsov et al., 1981), showing that anomalous R growth can be caused by a decrease of safety factor in propagation of the excitation wave.
mesh_terms: D000200:Action Potentials; D000818:Animals; D016275:Atrial Function; D004558:Electric Stimulation; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D011817:Rabbits
vernacular_title: Issledovanie anomal'nogo rosta refrakternosti serdechnoĭ tkani pri takhikardii.