HLA and psoriasis in the Chinese.
The HLA locus A, B and C antigen frequency of 70 unrelated Chinese patients with psoriasis were compared to that of 330 normal subjects. The frequency of 1, Aw30 and B13 were significantly elevated among patients compared to normals, even after correction for the number of antigens typed for. The joint occurrence of Aw30, B13 was observed in 20/70 (37.1%) patients compared to 8/330 /2.4%) normals (chi 2 = 60.7, RR = 16.1). Aw30 and B13 were found to be in significant linkage disequilibrium in patients as well as normals.
D002681:China / Q000208:ethnology; D006680:HLA Antigens; D006801:Humans; D011565:Psoriasis / Q000235:genetics / Q000276:immunology*; D012846:Singapore
D006680:HLA Antigens