Dantrolene sodium in the treatment of malignant hyperthermia. A case report.
The pharmacogenetic syndrome of malignant hyperthermia (MH) in response to general anaesthesia, though rare, is usually fatal when it does occur. A case of anaesthetic-induced MH arising in a 10-year-old girl during intranasal antrostomy and successfully treated with dantrolene sodium (Dantrium; SKF) is described. A treatment protocol for MH is appended. The importance of an awareness on the part of the clinician together with prompt reaction to early tell-tale signs is stressed.
D002648:Child; D003620:Dantrolene / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008305:Malignant Hyperthermia / Q000188:drug therapy*
D003620:Dantrolene