Behavioral effects of kainic acid injection into substantia nigra after ablation of the telencephalon.
Unilateral intranigral injection of kainic acid induced long-lasting contraversive turning and hyper-reactivity in rats. Surgical removal of the telencephalic forebrain failed to curtail said elicited effects, indicating that the critically involved output pathways from the substantia nigra do not invoke the telencephalon.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D007267:Injections; D007608:Kainic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D011759:Pyrrolidines / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013378:Substantia Nigra; D013687:Telencephalon / Q000502:physiology*; D013997:Time Factors
D011759:Pyrrolidines; D007608:Kainic Acid