Amphetamine-induced dysphoria in postmenopausal women.
Dextroamphetamine (0.15 mg/kg) intravenously administered to a group of normal postmenopausal women induced a dysphoric reaction with drowsiness, annoyance, sadness and anger. Young normal men, receiving the same dosage, responded with elation of mood and alertness. It is suggested that age and hypoestrogenism may alter the behavioural response to amphetamine.
D000328:Adult; D000342:Affective Symptoms / Q000139:chemically induced*; D000367:Age Factors; D003913:Dextroamphetamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008593:Menopause; D008875:Middle Aged
D003913:Dextroamphetamine