title: Novel topical fluoride delivery system I: remineralization of ground bovine teeth.
abstract: Laboratory studies were carried out on a newly conceived fluoride-containing remineralizing system with bovine teeth. The prototype fluoride delivery device involved micronized calcium fluoride maintained at the tooth surface with a cellulose film. Together with salivary calcium and phosphate (or simulated saliva), this system was able to generate and maintain the appropriate thermodynamic activity driving force for significant fluorapatite deposition in a reasonably short time (approximately 48 hr).
mesh_terms: D000818:Animals; D002417:Cattle; D004058:Diffusion; D005459:Fluorides / Q000378:metabolism*; D066298:In Vitro Techniques; D010316:Particle Size; D014070:Tooth / Q000378:metabolism*
chemical_list: D005459:Fluorides