title: The use of 17-epimethyltestosterone radioimmunoassay in following excretion of methandienone metabolites in urine.
abstract: A radioimmunoassay determination method was developed for 17-epimethyltestosterone (17 alpha-hydroxy-17-methyl-4-androstein-3-one). Excretion of metabolites during and after methandienone (17 beta-hydroxy-17-methyl-1,4-androstadien-3-one) administration was followed in human urine samples by RIA tests for methandienone and 17-epimethyltestosterone. While alternating peaks were found in both measured excretion curves, their addition results in a normal curve showing a plateau between the 3rd and 6th day of the drug administration. Furthermore, due to the presence of higher amounts of epi-configurated metabolites, the new test has a higher effectiveness in the detection of the metabolites.
mesh_terms: D000818:Animals; D003429:Cross Reactions; D008297:Male; D008696:Methandrostenolone / Q000652:urine*; D008777:Methyltestosterone / Q000652:urine*; D011817:Rabbits; D011863:Radioimmunoassay / Q000379:methods
chemical_list: D008696:Methandrostenolone; D008777:Methyltestosterone