title: Microclot generation (MCG) test in disease. Preliminary report.
abstract: Heparinized blood was taken up into capillary tubes and kept in vertical position at 37 degrees C for 24 hours to allow the red cells to sediment. Microclots appearing as radiant fibrin stars were seen under phase microscopy in the plasma portion of blood from certain patients. Such a positive microclot generation (MCG) test occurred in patients with some inflammatory diseases and cancer as well as in patients with certain skin disorders. The data suggest that the MCG test may serve in the detection of endotoxemia.
mesh_terms: D001799:Blood Sedimentation; D003460:Crystallization; D004731:Endotoxins / Q000097:blood*; D005260:Female; D005337:Fibrin / Q000032:analysis*; D006801:Humans; D007249:Inflammation / Q000097:blood; D008297:Male; D009369:Neoplasms / Q000097:blood; D011247:Pregnancy; D012871:Skin Diseases / Q000097:blood
chemical_list: D004731:Endotoxins; D005337:Fibrin