Dietary sodium, erythrocyte sodium concentration, sodium-stimulated lithium efflux and blood pressure.
1. There was a significant positive relationship between sodium-stimulated lithium efflux and systolic blood pressure (r = 0.512) in erythrocytes of black school children. Weight was also positively and significantly correlated with blood pressure. Although erythrocyte sodium concentration did not bear any significant relationship with blood pressure, it did bear significant inverse relationship with urinary sodium excretion. 2. High-school students were randomly assigned to either the experimental or the control group. In the former a reduction of about 70% in salt intake was achieved. After 24 days, the erythrocyte sodium concentration was significantly reduced in the experimental group. A non-significant decline in systolic blood pressure was observed in the experimental group; no change was detectable in the control group for either erythrocyte sodium concentration or systolic blood pressure.
D000293:Adolescent; D001794:Blood Pressure / Q000187:drug effects*; D002648:Child; D004039:Diet, Sodium-Restricted; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D008094:Lithium / Q000097:blood*; D012964:Sodium / Q000097:blood*; D012965:Sodium Chloride / Q000009:adverse effects
D012965:Sodium Chloride; D008094:Lithium; D012964:Sodium