title: Metal content ratio as a sensitive indicator of pulmonary edema.
abstract: The sensitivity to detect edema fluid in the lungs of rats exposed to 4, 2, 0.8, and 0.4 ppm O3 was estimated using the metal content ratio (Ca/Mg) and wet/dry weight ratio methods. Metal content ratios were determined by inductively coupled plasma-atomic emission spectrometer (ICP-AES). The detection limits were 0.8 and 2.0 ppm for the former and latter methods, respectively. A transitory increase of edema fluid was observed at day 1 in 0.8 and 0.4 ppm experiments by the Ca/Mg ratio method.
mesh_terms: D000818:Animals; D001826:Body Fluids / Q000032:analysis; D002118:Calcium / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D008297:Male; D008670:Metals / Q000378:metabolism*; D010126:Ozone / Q000633:toxicity; D011654:Pulmonary Edema / Q000139:chemically induced / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D008670:Metals; D010126:Ozone; D008274:Magnesium; D002118:Calcium