Heterotransplantation of human esophageal carcinoma to nude mice.
Transplantation to nude mice of 38 tumors originating from 36 human esophageal carcinomas was attempted. Growth of the grafts was obtained in 17 cases and 3 to 11 serial passages were performed in 4 cases. Tumors inoculated into subcutaneous tissue grew locally, but no metastasis nor local invasions were observed. The histological appearances of the grafts were similar to original tumors.
D000230:Adenocarcinoma / Q000473:pathology; D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D004938:Esophageal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008875:Middle Aged; D009368:Neoplasm Transplantation; D014183:Transplantation, Heterologous