[Interaction of monomeric components of nucleic acids with histone and polylysine in the presence of formaldehyde].
The ability of various nucleosides and nucleotides to bind to histone and polylysin upon formaldehyde treatment was investigated. It was shown that in protein or polypeptide preparations the guanine derivatives are present in much greater amounts than other nucleic base derivatives. No synthesis of stable products was observed thereby. It was assumed that the formation of the DNA - histone complex upon nuclear histone treatment with formaldehyde depends on the formaldehyde-induced reaction between the histone and guanine bases of DNA.
D004247:DNA; D005557:Formaldehyde; D006657:Histones; D007700:Kinetics; D010455:Peptides; D011107:Polylysine; D011485:Protein Binding; D012263:Ribonucleosides; D012265:Ribonucleotides; D013329:Structure-Activity Relationship
D006657:Histones; D010455:Peptides; D012263:Ribonucleosides; D012265:Ribonucleotides; D005557:Formaldehyde; D011107:Polylysine; D004247:DNA
Vzaimodeĭstvie monomernykh komponentov nukleinovykh kislot s gistonom i polilizinom v prisutstvii formal'degida.