[The influence of acetylosalicyclic acid on the cutaneous effect of UV-A (author's transl)].
This study deals with the influence of acetylosalicyclic acid (Colfarit Bayer) on the cutaneous effect of UV-A. Each of 24 volunteers received UV-A doses from 5 J/cm2 to 50 J/cm2. The immediate and the delayed UV-A erythema were reduced by prophylactic application of acetylosalicylic acid, 3 g daily three days before exposure and three days afterwards. 72 h after exposure to UV-A the reduction of delayed erythema formation was most obvious. Acetylosalicyclic acid had no influence, however, on the pigmentation caused by UV-A radiation.
D001241:Aspirin / Q000627:therapeutic use*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D012880:Skin Pigmentation / Q000187:drug effects; D013471:Sunburn / Q000517:prevention & control; D014466:Ultraviolet Rays / Q000009:adverse effects*
D001241:Aspirin
Der Einfluss von Azetylsalizylsäure auf die biologische Wirksamkeit von UV-A-Strahlen.