title: Complete amino acid sequences of bovine thymopoietins I, II, and III: closely homologous polypeptides.
abstract: Complete amino acid sequences were determined for thymopoietins I and II (revision), isolated from bovine thymus, and for thymopoietin III, a newly identified polypeptide isolated from bovine spleen. Thymopoietin III (TP-III) is a 49 amino acid monomeric peptide that shows minor microheterogeneity at residue 34. The three thymopoietins have largely identical sequences yet some distinct differences, suggesting very recent evolution from a common gene. The complete amino acid sequences are (Formula: see text).
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001322:Autoanalysis; D005075:Biological Evolution; D002417:Cattle; D005796:Genes; D013154:Spleen / Q000032:analysis*; D013329:Structure-Activity Relationship; D013946:Thymopoietins / Q000302:isolation & purification; D013950:Thymus Gland / Q000032:analysis; D013951:Thymus Hormones / Q000302:isolation & purification
chemical_list: D013946:Thymopoietins; D013951:Thymus Hormones; C032841:thymopoietin III