Absorption of isosorbide dinitrate by PVC infusion bags and administration sets.
Isosorbide dinitrate is shown to be absorbed onto PVC bags and administration sets, resulting in a fall in potency to about 70-80% of its initial value in the first 15-30 min of an i.v. infusion. The drug was not absorbed by glass or polypropylene.
D000042:Absorption; D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D007263:Infusions, Parenteral / Q000295:instrumentation; D007548:Isosorbide Dinitrate / Q000032:analysis*; D011143:Polyvinyl Chloride; D011145:Polyvinyls; D013997:Time Factors
D011145:Polyvinyls; D011143:Polyvinyl Chloride; D007548:Isosorbide Dinitrate