Myocardial infarction in familial hyper-alpha and hypo-beta-lipoproteinaemia.
This is the documentation of an acute myocardial infarction in a 45-year-old woman with familial hyper-alpha- and hypo-beta-lipoproteinaemia. This dyslipoproteinaemia has been rarely associated with clinical evidence of ischaemic heart disease. Documentation of angiographically normal coronary arteries in this patient is consistent with the concept that increased alpha-lipoprotein (HDL) and low beta-lipoprotein (LDL) may prevent atherosclerosis. Thus, myocardial infarction in patients with this dys-lipoproteinaemia should be attributable to factors other than coronary atherosclerosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D006951:Hyperlipoproteinemias / Q000235:genetics*; D006995:Hypobetalipoproteinemias / Q000235:genetics*; D007009:Hypolipoproteinemias / Q000235:genetics*; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*
D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL