Aminophylline in ureterolithiasis: preliminary report.
Aminophylline (3 mg/kg i.v.) was injected in six patients with colicky pain caused by a ureter stone. In all but one this theophylline derivative caused a prompt and subjectively clear decrease in pain lasting from 30 min to 2 h. Serum levels over 12 microgram/ml were associated with good pain relief. A controlled study with an intravenous aminophylline infusion is warranted, because the pain-decreasing effect was too short-lasting after a single injection.
D000328:Adult; D000368:Aged; D000628:Aminophylline / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy; D013806:Theophylline / Q000097:blood; D013997:Time Factors; D014514:Ureteral Calculi / Q000188:drug therapy*
D000628:Aminophylline; D013806:Theophylline