title: A simple restraining device for chronic pharmacokinetic and metabolism studies in rats.
abstract: The construction of a simple Plexiglas restraining device for chronically cannulated rats is described. The apparatus is ideally suited for blood sampling and the collection of urine and feces during chronic pharmacokinetic and drug metabolism studies.
mesh_terms: D000818:Animals; D007700:Kinetics; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D051381:Rats / Q000378:metabolism*; D012149:Restraint, Physical / Q000379:methods / Q000662:veterinary*
chemical_list: D004364:Pharmaceutical Preparations