title: [Hemodynamics of the gastroduodenal circulation (author's transl)].
abstract: The regional blood flow of the dog's stomach and upper part of the duodenum is measured by radioactive microspheres. A complete surgical interruption of vascular connections between antrum and corpus changes blood flow distribution, as measured 2 weeks after operation. We find a significant fall of flow to the mucosa of the corpus and the muscular layer of the antrum. Mucosa and muscularis of the canine stomach are supplied by different sources: The arteries of the muscularis, which show extramural origin, are mainly supplied by the left gastric vessels. The gastric mucosa--even of the corpus--shows main blood supply from the arteries of the gastroduodenal region. Gastric secretion shows normal response on stimulation by Pentagastrin. Thus an accidental vagotomy is excluded as a possible cause of the registered flow changes. The effect of Pentagastrin on the gastroduodenal circulation is interpreted an an occlusion of arteriovenous shunts.
mesh_terms: D000818:Animals; D004285:Dogs; D004386:Duodenum / Q000098:blood supply*; D005750:Gastric Juice / Q000378:metabolism; D005753:Gastric Mucosa / Q000098:blood supply; D006439:Hemodynamics / Q000187:drug effects; D009130:Muscle, Smooth / Q000098:blood supply; D010418:Pentagastrin / Q000494:pharmacology; D012039:Regional Blood Flow / Q000187:drug effects; D013270:Stomach / Q000098:blood supply*
chemical_list: D010418:Pentagastrin
vernacular_title: Zur Hämodynamik der gastroduodenalen Zirkulation. Eine tierexperimentelle Studie am Hundemagen.