title: Continuous measurement of DTPA-clearance in extracorporeal detoxification circuits.
abstract: A new method for investigating clearances is described. DTPA labelled with technetium 99m (MW: 496 daltons) is used as an agent to be measured. Continuous determination of the DTPA-clearance is possible in extracorporeal detoxification circuits including dialyzers, hemofilters and hemoperfusion columns. As an example, DTPA-clearances are given for two different dialyzers. In comparison to clearance measurements of peak 7, DTPA-clearance was very similar to that obtained for peak 7.
mesh_terms: D001322:Autoanalysis; D006801:Humans; D004369:Pentetic Acid; D006435:Renal Dialysis; D013667:Technetium; D014118:Toxins, Biological / Q000097:blood / Q000302:isolation & purification*; D014511:Uremia / Q000097:blood / Q000628:therapy*
chemical_list: D014118:Toxins, Biological; C026865:uremia middle molecule toxins; D013667:Technetium; D004369:Pentetic Acid