title: Effects of progressively longer durations of monocular deprivation on development of visuocortical receptive fields in the rabbit.
abstract: Three groups of rabbits were reared with monocular eyelid suture. Percentages of cells with various receptive field types were determined by recording in the deprived visual cortex of animals 30-35 days, 46-55 days, and 20-36 months old. These results, together with previously published data from two other groups of monocularly deprived rabbits, are described relative to normative data for 9-10-day-old and adult rabbits. During the first postnatal year cells in the deprived visual cortex acquire normal adult proportions of receptive field types, but do so over a longer course than that which is characteristic of cells in non-deprived visual cortex. With continued deprivation for 2-3 years there is a subsequent loss of oriented type cells and a corresponding increase in non-responsive cells.
mesh_terms: D000818:Animals; D004594:Electrophysiology; D011817:Rabbits; D013997:Time Factors; D014786:Vision Disorders / Q000503:physiopathology*; D014793:Visual Cortex / Q000166:cytology / Q000254:growth & development* / Q000502:physiology; D014794:Visual Fields