Rat embryonic and foetal erythrocytes. High 2,3-bisphosphoglycerate and ATP and low oxygen affinity in vitro for nucleated embryonic cells.
Embryonic nucleated red cells of the rat have high ATP and 2,3-bisphosphoglycerate and relatively low oxygen affinity. During foetal life they are replaced by large non-nucleated red cells with high ATP, low bisphosphoglycerate and high oxygen affinity. After birth, small non-nucleated red cells with high bisphosphoglycerate and low oxygen affinity rapidly predominate.
D000255:Adenosine Triphosphate / Q000097:blood*; D000367:Age Factors; D000818:Animals; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004622:Embryo, Mammalian / Q000502:physiology; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D011247:Pregnancy; D051381:Rats
D004163:Diphosphoglyceric Acids; D000255:Adenosine Triphosphate; D010100:Oxygen