Activity of adenosine deaminase allelic forms in intact erythrocytes and in lymphocytes.
The distribution of ADA activity has been studied for ADA 1 and ADA 2-1 individuals in intact and lysed erythrocytes and in lymphocyte lysates. ADA activity in intact RBC is 20-30% lower than in lysates, in lymphocytes it is 10 times higher. The difference between ADA 1 and ADA 2-1 mean enzyme activities which we previously described in RBC lysates has been found also in intact RBC and in lymphocyte lysates.
D000243:Adenosine Deaminase / Q000097:blood* / Q000235:genetics; D000328:Adult; D000483:Alleles; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006461:Hemolysis; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*; D008297:Male; D009700:Nucleoside Deaminases / Q000097:blood*
D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase