title: Glucose dehydrogenase polymorphism in man.
abstract: An isoelectric focusing method for human GDH is described which reveals seven GDH phenotypes. Family studies demonstrate that the variation is genetically determined by three alleles at an autosomal locus with gene frequencies GDH1 = 0.723, GDH2 = 0.194, GDH3 = 0.083. Linkage analysis shows that GDH may be closely linked to PGD on chromosome 1.
mesh_terms: D000483:Alleles; D002237:Carbohydrate Dehydrogenases / Q000235:genetics*; D005787:Gene Frequency; D008040:Genetic Linkage; D005948:Glucose Dehydrogenases / Q000235:genetics*; D006801:Humans; D007525:Isoelectric Focusing; D010375:Pedigree; D010641:Phenotype; D011110:Polymorphism, Genetic; D014018:Tissue Distribution
chemical_list: D002237:Carbohydrate Dehydrogenases; D005948:Glucose Dehydrogenases