Reaction spectrum of HBe antibodies.
Significant differences concerning the in vitro reaction spectrum were found between two groups of 30 anti-HBe samples, one from apparently healthy HBsAg carriers, the other from HBsAg-positive acute viral hepatitis (AVH) patients : the mean number of positive reactions per anti-HBe sample was of 7.00 +/- 2.25 in the former and of 3.60 +/- 1.42 in the latter group. The broader reaction spectrum of anti-HBe from apparently healthy subjects (overall positivity percentage--54%, as against 26% in AVH patients) suggests some explanations regarding the different evolution modalities of hepatitis B virus infection in terms of the organism's capacity to develop a specific response.
D000914:Antibodies, Viral / Q000032:analysis*; D000915:Antibody Affinity; D000937:Antigen-Antibody Reactions; D002353:Carrier State / Q000276:immunology*; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006511:Hepatitis B Antigens / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000032:analysis / Q000276:immunology*; D006801:Humans
D000914:Antibodies, Viral; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens