Intestinal pharmacomanometry and glucose tolerance: evidence for two antagonistic dopaminergic mechanisms in the human.
In this article cumulative data are presented dealing with the existence of more than one dopamine receptor in mammals. In addition, evidence is presented for the existence of two antagonistic dopamine-functional expressions in the human. This fact, along with the disclosure of new dopaminergic agonistic and antagonistic drugs, should prove useful in the management of diseases in which these drugs have proven to be good therapeutic tools.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003106:Colon / Q000294:innervation*; D004298:Dopamine / Q000502:physiology*; D018492:Dopamine Antagonists; D005769:Gastrointestinal Motility / Q000187:drug effects; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D008365:Manometry; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*; D012007:Rectum / Q000294:innervation*; D012701:Serotonin / Q000097:blood; D013469:Sulpiride / Q000494:pharmacology
D001786:Blood Glucose; D018492:Dopamine Antagonists; D011954:Receptors, Dopamine; D012701:Serotonin; D013469:Sulpiride; D006220:Haloperidol; D004298:Dopamine