Application of cellulose acetate electrophoresis to globin chain separation for antenatal diagnosis of beta thalassemia.
Application of cellulose acetate electrophoresis to globin chain separation for antenatal diagnosis of beta thalassemia has been studied. A good correlation between an electrophoretic and a chromatographic method on carboxymethylcellulose was found and the diagnoses suggested by both methods were always coincident. The electrophoretic method was also utilized for HbS/beta-thalassemia diagnosis.
D019411:Clinical Laboratory Techniques; D004588:Electrophoresis, Cellulose Acetate / Q000379:methods; D005260:Female; D005914:Globins / Q000302:isolation & purification*; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013789:Thalassemia / Q000175:diagnosis*
D006451:Hemoglobin, Sickle; D005914:Globins