Effect of dihydroxydibutylether on the lithogenic index of patients with cholesterol gallstones.
Daily administration of 900 mg dihydroxydibutylether (DHBE) produced a significant reduction of lithogenic index in patients with cholesterol gallstones. After treatment with placebo, in the same subjects the lithogenic index rises significantly. The activity of DHBE is not casual.
D000328:Adult; D001646:Bile / Q000032:analysis / Q000187:drug effects*; D000440:Butanols / Q000494:pharmacology*; D002756:Cholagogues and Choleretics / Q000494:pharmacology*; D002769:Cholelithiasis / Q000188:drug therapy*; D002784:Cholesterol / Q000378:metabolism*; D004987:Ethers / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis; D008297:Male; D008875:Middle Aged
D000440:Butanols; D002756:Cholagogues and Choleretics; D004987:Ethers; D008055:Lipids; D002784:Cholesterol; C000987:4,4'-oxydi-2-butanol