Effect of prazosin on renal function in chronic congestive cardiac failure.
Prazosin was used as additional therapy in seven patients with severe chronic congestive cardiac failure. The effect on renal function in this situation was measured. Renal function improved in four of the seven patients, and this improvement was associated with improvement in their clinical condition; in two other patients, modest improvement in renal function was not associated with symptomatic relief which may have been the result of a gain in weight.
D000328:Adult; D000368:Aged; D001835:Body Weight / Q000187:drug effects; D003404:Creatinine / Q000097:blood; D006073:Gout / Q000139:chemically induced; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011224:Prazosin / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D011799:Quinazolines / Q000494:pharmacology*; D013610:Tachycardia / Q000139:chemically induced; D014508:Urea / Q000097:blood; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology
D011799:Quinazolines; D014665:Vasodilator Agents; D014508:Urea; D003404:Creatinine; D011224:Prazosin