title: Prevention of hepatitis B virus transmission by the gastrointestinal fibrescope. Successful disinfection with an aldehyde liquid.
abstract: In a prospective study we examined the efficacy of a standardized disinfection method in preventing the transmission of hepatitis B virus by the gastrointestinal fibrescope. Four HBSAg- and Dane particle-positive patients who have been endoscoped served as possible sources of hepatitis B virus infection. We cleaned the instrument with a 10% aldehyde liquid and used it immediately thereafter in 10 HBSAg-negative patients. Eight of them were followed-up for 7 months after the endoscopic procedure. None of them showed serological evidence of an endoscopically transmitted hepatitis B virus infection. It is concluded that disinfection with an aldehyde liquid is effective in preventing the transmission of hepatitis B virus by the fibrescope.
mesh_terms: D000447:Aldehydes; D003428:Cross Infection / Q000517:prevention & control*; D004203:Disinfection / Q000379:methods*; D004724:Endoscopy / Q000009:adverse effects; D005336:Fiber Optic Technology; D006509:Hepatitis B / Q000517:prevention & control*; D006801:Humans; D011446:Prospective Studies; D013242:Sterilization / Q000379:methods*
chemical_list: D000447:Aldehydes