Self-catalysed, O2-independent inactivation of NADPH- or dithionite-reduced microsomal cytochrome P-450 by carbon tetrachloride.
D000693:Anaerobiosis; D000818:Animals; D002248:Carbon Monoxide / Q000378:metabolism; D002251:Carbon Tetrachloride / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004227:Dithionite / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000201:enzymology*; D009249:NADP / Q000378:metabolism*; D010084:Oxidation-Reduction; D010100:Oxygen; D051381:Rats; D011919:Rats, Inbred Strains; D013447:Sulfites / Q000378:metabolism*
D013447:Sulfites; D004227:Dithionite; D009249:NADP; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D002251:Carbon Tetrachloride; D010100:Oxygen