title: [Age and morphofunctional characteristics of celiac ganglia chromaffin tissue in normal and hypokinetic animals].
abstract: Accumulation of chromaffin cells (ChC) in the celiac nodes have been studied in young (6-month-old) and old (28-30-month-old) rats; 50 intact and 32 rats kept at hypokinesia for 6 weeks have been used. In the young intact rats accumulation of the ChC have been found in 51% and in the old ones-in 82% of cases. In the young rats 85% of the accumulations are localized inside the nodes, 4%-in their trunks and 12%-near the nodes, and in the old rats-69%, 8% and 23%, respectively. In the young and in the old rats the ChC section area is 133+/-4, 147+/-13 mkm2, nuclei-33.7+/-0.7 and 36.9+/=1.3 mkm2 and nuclear-plasmic relations-0.34 and 0.33, respectively. In the young rats the ChC with a high perikaryon density make 40%, with middle-32%, with low-28%, in the old rats-40%, 36% and 24%, respectively. The greater the ChC, the smaller the nuclear-plasmic ratio and perikaryon density. Low indices on the density and nuclear-plasmic ratio correspond to the excretion phase, and the high indices-to prevalence of synthesis and accumulation. These correlations reflect the morpho-functional profile of the chromaffin component in the nodes. Thus, with aging the chromaffin tissue of the celiac nodes is represented by a greater number of accumulations, while the morpho-functional indices of the ChC accumulations remain unchanged. Under hypokinesia, in the young and old rats mass of the chromaffin tissue decreases. The body and the nuclear area of the ChC decreases and by the end of the experiment it makes: in the young rats 104+/-5 and 30.6+/-1.1 mkm2, and in the old rats-100+/-3 and 29.7+/-2 mkm2. Rearrangement of the morpho-functional profile, manifested in increasing content of the ChC with high density and in decreasing congulatory role in the celiac nodes decrease. By the end of the experiment, in young rats normal function is approaching, in the old rats-the rearrangement is of stable character.
mesh_terms: D000367:Age Factors; D000818:Animals; D002447:Celiac Plexus / Q000166:cytology*; D002838:Chromaffin System / Q000166:cytology*; D009068:Movement; D009457:Neuroglia / Q000166:cytology; D009474:Neurons / Q000166:cytology; D051381:Rats; D012149:Restraint, Physical
vernacular_title: Vozrastnaia morfofunktsional'naia kharakteristika khromaffinnoĭ tkani chrevnykh uzlov v norme i pri gipokinezii.