[Age-related changes in the cholin- and adrenergic innervation of the human heart].
The hearts of 35 patients of different age have been studied. The cholinergic innervation reaches full differentiation by the age of 30, its involution begins after 50. The adrenergic innervation is most manifest in children, its involution begins from 30. After 60 the nervous plexuses of the heart are fully devoid of catecholamines. The sensitivity of the myocardium to adrenalin at different age levels is roughly the same.
D000293:Adolescent; D000328:Adult; D000375:Aging; D002648:Child; D006321:Heart / Q000033:anatomy & histology / Q000294:innervation*; D006325:Heart Atria / Q000294:innervation; D006346:Heart Septum / Q000294:innervation; D006352:Heart Ventricles / Q000294:innervation; D006801:Humans; D008875:Middle Aged; D011941:Receptors, Adrenergic / Q000502:physiology*; D011950:Receptors, Cholinergic / Q000502:physiology*
D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic
Vozrastnye izmeneniia kholi- i adrenergicheskoĭ innervatsii serdtsa cheloveka.