title: Percutaneous absorption of chlorhexidine in neonatal cord care.
abstract: The percutaneous absorption of chlorhexidine during its routine use in topical antiseptic preparations used in umbilical cord care was investigated by determining plasma chlorhexidine concentrations at ages 5 and 9 days. These showed that percutaneous absorption of chlorhexidine occurred in preterm neonates treated with a 1% solution of chlorhexidine in ethanol, but not in term infants similarly treated, or in preterm infants treated only with a dusting powder containing 1% chlorhexidine and 3% zinc oxide.
mesh_terms: D002710:Chlorhexidine / Q000378:metabolism*; D006801:Humans; D007224:Infant Care / Q000379:methods; D007231:Infant, Newborn; D007234:Infant, Premature; D012869:Skin Absorption; D014470:Umbilical Cord
chemical_list: D002710:Chlorhexidine