[The effect of ethacrynic acid and ouabain on the endolymphatic space of the frog (author's transl)].
Ethacrynic acid, but not ouabain, administered into the endolymph entails a decrease in the endolymphatic potential of frogs. Injection of either ouabain or ethacrynic acid into the perilymph causes a decrease in the DC-potential. Intraperitoneal administration of ethacrynic acid (750 mg/kg) and ouabain (0.5 mg/kg) has no effect on the endolymphatic potential of the frog.
D000818:Animals; D007758:Ear, Inner / Q000187:drug effects*; D004712:Endolymphatic Sac / Q000187:drug effects*; D004976:Ethacrynic Acid / Q000494:pharmacology*; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D010042:Ouabain / Q000494:pharmacology*; D011898:Ranidae
D010042:Ouabain; D004976:Ethacrynic Acid
Uber die Wirkung von Etacrynsäure und Ouabain auf das Endolymphsystem des Froschohres.