Correlation between serum calcitonin and calcium levels and bone calcium contents in rats.
The serum calcium and calcitonin levels and the calcium content of femora were measured in rats from the time of birth till 1.5 years of age. The serum calcium level was within the normal range of variation all over the measuring period with a high on the 10th day and a low on the 50th day of age. The serum calcitonin level was the highest in newborn animals, the lowest in 50-day old animals and reached a steady level with a slow rise on 120th day of age. The bone mineralisation abruptly increased in young animals and reached a constant value on the 20th day of age. The correlation of these values with the number of C cells determined previously in different ages is discussed.
D000375:Aging; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D002116:Calcitonin / Q000097:blood*; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D008297:Male; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000166:cytology / Q000254:growth & development
D002116:Calcitonin; D002118:Calcium