title: [Early behavioral and neurofunctional deviations following prenatal carbon disulfide exposure].
abstract: The effect of prenatal carbon disulphide exposure with a concentration 10 and 0.33 mg/m3 is studied (MAC for a working zone and atmospheric air resp.) upon the behavioural and neurofunctional development of the generation. A neurotoxicological screening was employed for the assessment of the early postnatal development. It was established that carbon disulphide with a MAC level of the working zone, disturbed the postnatal development without inducing congenital malformations, inducing buit sensory, neurofunctional and behavioural deviations. The results stress upon the high sensitivity of the central nervous system of the growing fetus to carbon disulphide and confirm the expedience of the utilization of neurobehavioural testing as a sensitive method for detecting of sequelae of the effect of prenatal stress with low intensity.
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002246:Carbon Disulfide / Q000633:toxicity*; D002490:Central Nervous System / Q000187:drug effects* / Q000254:growth & development; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D005260:Female; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D012018:Reflex / Q000187:drug effects
chemical_list: D002246:Carbon Disulfide
vernacular_title: Ranni povedencheski i nevrofunktsionalni otkloneniia sled prenatalna serovŭglerodna espozitsiia.