title: Acceleration stress-induced Wolff-Parkinson-White Syndrome with marked ST-segment depression.
abstract: Exercise can affect preexcitation in several ways. The possible presence of catecholamine-sensitive bypass, stimulated during periods of high stress, was recently reported. In addition to a direct effect on the preexcitation, when the preexcitation pattern exists, exercise-induced ST-segment changes may occur which preclude stress testing for coronary artery disease detection. Current high-performance fighter pilots, flying new generation aircraft, are under severe stress during aerial combat maneuvering when they are exposed to high sustained +Gz (head-to-foot) acceleration stress. We report the occurrence of a +Gz acceleration-induced episode of preexcitation with marked ST-segment depression in a healthy asymptomatic aircrewman. Autonomic imbalance, with high catecholamine levels developed during +Gz stress, may be the etiology of this preexcitation episode.
mesh_terms: D000054:Acceleration / Q000009:adverse effects*; D000328:Adult; D004562:Electrocardiography; D006112:Gravitation; D006801:Humans; D008297:Male; D013312:Stress, Physiological / Q000150:complications*; D014927:Wolff-Parkinson-White Syndrome / Q000209:etiology* / Q000503:physiopathology