Preliminary pharmacological data on synthetic peptides related to dermorphin.
The preliminary pharmacological data on synthetic peptides related to dermorphin (opiate-heptapeptide) are reported. The tetrapeptide, corresponding to the N-terminal sequence of dermorphin is a minimum requirement for significant opiate-activity in vitro.
D000818:Animals; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009842:Oligopeptides / Q000494:pharmacology*; D018847:Opioid Peptides; D014649:Vas Deferens / Q000187:drug effects
D009842:Oligopeptides; D018847:Opioid Peptides; C030058:dermorphin