Screening for occupational vitiligo in workers exposed to hydroquinone monomethyl ether and to paratertiary-amyl-phenol.
Two men reported previously with vitiligo after occupational exposure to hydroquinone monomethyl ether (HMME) have been reviewed after eight years. Repigmentation of significant degree was found in one man and of limited degree in the other. One hundred and sixty-nine men in the same works have been screened with Wood's light for evidence of vitiligo. No cases were found in the 148 men exposed to HMME (colleagues who screened 100 men exposed to HMME in two other factories also found no case) or in the 129 who had been exposed to paratertiary-amyl-phenol. Loss of light reflection on Wood's light examination was observed in 13 men due to scars or to other skin disorders.
D000328:Adult; D000840:Anisoles / Q000009:adverse effects*; D002617:Chemical Industry; D006801:Humans; D008297:Male; D008403:Mass Screening; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis*; D010636:Phenols / Q000009:adverse effects*; D014820:Vitiligo / Q000139:chemically induced / Q000175:diagnosis*
D000840:Anisoles; D010636:Phenols; C009760:mequinol; C019566:p-tert-amylphenol