[Effect of fetoplacental factors on in vitro proliferation of lymphocytes and non-lymphoid cells].
The effect of extracts of placenta, amniotic fluid, serum of pregnant women and newborn infants on PHA-stimulated proliferative activity of lymphocytes and proliferation of non-lymphoid cells (L-cells) was studied. The inhibiting effect decreased in the series: placenta -- amniotic fluid -- serum of pregnant women. The effect on L-cells was similar to that on lymphocytes. It is suggested that the biological samples under study contained factors having non-specific immunosuppressive effect.
D000653:Amniotic Fluid; D002823:Chorion; D005260:Female; D005865:Gestational Age; D006801:Humans; D007166:Immunosuppressive Agents / Q000032:analysis; D007231:Infant, Newborn; D007739:L Cells; D008214:Lymphocytes; D008938:Mitosis; D010835:Phytohemagglutinins / Q000494:pharmacology; D010924:Placental Extracts / Q000494:pharmacology; D011247:Pregnancy; D014020:Tissue Extracts / Q000494:pharmacology*; D014470:Umbilical Cord
D007166:Immunosuppressive Agents; D010835:Phytohemagglutinins; D010924:Placental Extracts; D014020:Tissue Extracts
Vliianie fetoplatsentarnykh faktorov na proliferatsiiu in vitro limfotsitov i nelimfoidinykh kletok.