title: Responses of fluke-infected and fluke-free cattle to experimental reinfection with Salmonella dublin.
abstract: Cattle, aged nine to 18 months, were given sublethal doses of Salmonella dublin either intravenously, orally on two occasions, or by contact for 19 to 22 weeks with a persistent excretor. When challenged by intravenous injection of 10(9) S dublin at 10 to 22 weeks after their first exposure to S dublin 22 out of 36 animals survived. All similarly challenged cattle, which had not been previously exposed to S dublin, died. Infection with Fasciola hepatica did not alter the ability of cattle to survive reinfection with S dublin but the bacteria persisted in the tissues and were excreted in the faeces of fluke-infected animals for longer than in fluke-free animals. The ability to survive reinfection and to eliminate S dublin from the tissues was apparently unrelated to agglutinating antibody titres or delayed hypersensitivity.
mesh_terms: D000373:Agglutinins / Q000032:analysis; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000382:microbiology; D005211:Fascioliasis / Q000150:complications / Q000276:immunology / Q000662:veterinary*; D005243:Feces / Q000382:microbiology; D005260:Female; D005334:Fever / Q000662:veterinary; D008297:Male; D012475:Salmonella / Q000302:isolation & purification; D012481:Salmonella Infections, Animal / Q000150:complications / Q000276:immunology* / Q000382:microbiology; D012882:Skin Tests / Q000662:veterinary
chemical_list: D000373:Agglutinins