[Quantitative thin-layer chromatographic estimation of aminophenazone (I.N.N.), 4-methylaminophenazone and 4-aminophenazone in plasma (author's transl)].
A TLC method for measurement of aminophenazone (1) and of its degradation products 4-methylaminophenazone (2) and 4-aminophenazone (3) in plasma was described. After chloroform extraction amd separation on Silufol plates the substances were stained by ferric chloride/potassium hexacyanotoferrate(III) and the area of the spots was measured. Concentrations from 1 to 25 micrograms 1, 2 and 3 per ml plasma could be estimated.
D000632:Aminopyrine / Q000031:analogs & derivatives* / Q000097:blood*; D000675:Ampyrone / Q000097:blood*; D000983:Antipyrine / Q000031:analogs & derivatives*; D002855:Chromatography, Thin Layer / Q000379:methods; D004177:Dipyrone / Q000031:analogs & derivatives* / Q000097:blood; D006801:Humans; D047069:Pyrazolones; D013997:Time Factors
D047069:Pyrazolones; D000632:Aminopyrine; D000675:Ampyrone; D004177:Dipyrone; C008667:noramidopyrine; D000983:Antipyrine
Quantitative dünnschichtchromatografische Bestimmung von Aminophenazon (I.N.N.), 4-Methylaminophenazon und 4-Aminophenazon im Plasma.