[Effect of salicylic acid on the blanching effect of flumethasone pivalate (author's transl)].
Test results are reported of the effect of salicylic acid on the vasoconstrictive effect of flumethasone pivalate. In specific, the depigmentation of the skin (identical with increase in lightness of the skin) following topical application of flumethasone pivalate was investigated with the aid of an improved spectrophotometric method. Using numeric lightness evaluation it was possible to demonstrate that salicylic acid increases the vasoconstriction.
D000328:Adult; D005443:Flumethasone / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D008297:Male; D012459:Salicylates / Q000494:pharmacology*; D020156:Salicylic Acid; D012867:Skin / Q000098:blood supply; D012880:Skin Pigmentation / Q000187:drug effects*; D014661:Vasoconstriction / Q000187:drug effects
D012459:Salicylates; C005565:flumethasone pivalate; D005443:Flumethasone; D020156:Salicylic Acid
Der Einfluss der Salicylsäure auf den Abblassungseffekt von Corticosteroid-Dermatica, dargestellt am Beispiel des Flumetason-pivalat.