Effect of guar gum on blood lipids.
The effect of guar gum in capsule form on serum total cholesterol, triglycerides, and lipoprotein cholesterol (very low-density lipoproteins, low-density lipoproteins, and high-density lipoproteins) was studied in healthy volunteers in this double-blind study. Twenty-four subjects equally divided into treatment and placebo groups, received 9.0 g/day of guar and glucose in 600 mg identical capsules, respectively, for 4 wk under conditions of constant body weight and dietary stability. Guar significantly lowered serum total cholesterol (16.6% p less than 0.05) and low-density lipoprotein cholesterol (25.6% p less than 0.05) but had no significant effect (p less than 0.05) on serum triglycerides, high-density lipoproteins and very low-density-lipoprotein cholesterol. No significant changes (p greater than 0.05) were seen in blood lipids in the placebo group.
D000328:Adult; D002214:Capsules; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL; D004311:Double-Blind Method; D005260:Female; D005685:Galactans / Q000008:administration & dosage*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008351:Mannans / Q000008:administration & dosage*; D008875:Middle Aged; D053149:Plant Gums; D011134:Polysaccharides / Q000008:administration & dosage*
D002214:Capsules; D008078:Cholesterol, LDL; D005685:Galactans; D008055:Lipids; D008077:Lipoproteins, LDL; D008351:Mannans; D053149:Plant Gums; D011134:Polysaccharides; D002784:Cholesterol; C007894:guar gum