title: An Indian family with postaxial polydactyly in four generations.
abstract: An Indian family was observed with postaxial polycactyly in four generations. Of the twelve affected cases, eleven were male and one was female. The affected males showed postaxial polydactyly Type A in both hands and feet. The affected female showed polysyndactyly and both Types A and B postaxial polydactyly. Study of this family strongly suggests a common causal factor for postaxial polydactyly Types A and B and polysyndactyly. The observations also support an autosomal dominant pattern of inheritance and a high degree of genetic heterogeneity in ths malformation.
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D010375:Pedigree; D014034:Toes / Q000002:abnormalities*