[Treatment of chronic osteomyelitis with Taurolin-Gel (author's transl)].
A study was made to ascertain the effect of Taurolin [Bis-(1-dioxo-perhydro-1, 2, 4-thiadiazinyl-4)-methan]*-Agarose resp. Taurolin -Collagen, using as model a chronic osteomyelitis in a dog's femur. The result was verified by means of X-rays, bone scans, intermittent bacteriological checks and, finally, histology. Taurolin, a chemotherapeuticum derived from the aminosulfonic acid, Taurin, was proven to be compatible. It led to regression of the osteomyelitis.
D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D004285:Dogs; D005264:Femoral Fractures / Q000601:surgery; D005593:Fracture Fixation, Internal; D010019:Osteomyelitis / Q000188:drug therapy*; D013530:Surgical Wound Infection / Q000188:drug therapy; D013654:Taurine / Q000031:analogs & derivatives*; D013829:Thiadiazines / Q000627:therapeutic use*; D013843:Thiazines / Q000627:therapeutic use*
D000891:Anti-Infective Agents, Local; D013829:Thiadiazines; D013843:Thiazines; D013654:Taurine; C012566:taurolidine
Behandlung der chronischen Osteomyelitis mit Taurolin-Gel-Stäben.