[Effect of the quality of regenerated butanol on the process of producing the potassium salt of benzylpenicillin].
The effect of water and butylacetate contained in butanol used in production of potassium benzylpenicillin on the yield and quality of the latter was studied. It was found that normal butyl alcohol with the moisture level not more than 0.2 per cent provided the optimal conditions for the antibiotic production. Butyl acetate contained in butanol in an amount of 25 per cent was shown also to have practically no effect on the yield and quality of benzylpenicillin.
D000085:Acetates / Q000494:pharmacology; D000440:Butanols / Q000032:analysis / Q000494:pharmacology*; D002849:Chromatography, Gas; D010400:Penicillin G / Q000138:chemical synthesis*; D011786:Quality Control; D012995:Solubility; D014867:Water / Q000494:pharmacology
D000085:Acetates; D000440:Butanols; D014867:Water; C006848:butyl acetate; D010400:Penicillin G
Issledovanie vliianiia kachestva regenerirovannogo butanola na protsess polucheniia kalievoĭ soli benzilpenitsillina.