Determination of thio compounds in urine of workers exposed to carbon disulfide.
Metabolites of carbon disulfide excreted into the urine of viscose workers are detectable by application of a nonselective assay for the determination of thio compounds. Enhanced secretion of thio compounds occurred especially at the end of the workday in exposed workers. A classification of urine samples according to the degree of exposure gave evidence for a relation between exposure to carbon disulfide and excretion of thio compounds in urine. The presence of 2-thiothiazolidine-4-carboxylic acid in urine of viscose workers was indicated by TLC, UV-spectrometry, and HPLC.
D000393:Air Pollutants / Q000032:analysis*; D000395:Air Pollutants, Occupational / Q000032:analysis*; D002246:Carbon Disulfide / Q000652:urine*; D003404:Creatinine / Q000652:urine; D006801:Humans; D008297:Male; D013455:Sulfur / Q000652:urine*; D013783:Textile Industry; D013844:Thiazoles / Q000652:urine; D053778:Thiazolidines
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D013844:Thiazoles; D053778:Thiazolidines; C031677:2-thioxo-4-thiazolidinecarboxylic acid; D013455:Sulfur; D003404:Creatinine; D002246:Carbon Disulfide