[Ultrastructure of the intraorganic nerve ganglia of the heart in experimental myocardial infarct].
Significant changes of the ultrastructure of all nervous elements develop in nervous ganglia of rabbit hearts in experimental myocardial infarction (EMI) caused by ligation of the anterior descending artery. Changes in the nucleus and cytoplasmic organelles of cardiac neurons within the first few hours postoperation appear to indicate an active state of nerve cells. Subsequently, probably due to overirritation and partial ischemia, degenerative changes begin to appear which may lead to the loss of some neurocytes. Rearrangement of synaptic contacts observed, as a rule, after 3 days of EMI may indicate an interruption of connections between preganglionar fibers and neurocytes. Considerable changes in cholinergic nervous elements of cardiac ganglia are a part of the morphological substrate of disturbed nervous influences on the myocardium in infarction
D000818:Animals; D005724:Ganglia / Q000648:ultrastructure*; D006321:Heart / Q000294:innervation*; D008297:Male; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000648:ultrastructure*; D009411:Nerve Endings / Q000648:ultrastructure; D009412:Nerve Fibers / Q000648:ultrastructure; D011817:Rabbits; D013569:Synapses / Q000648:ultrastructure; D013997:Time Factors
Ul'trastruktura intraorgannykh nervnykh gangliev serdtsa pri éksperimental'nom infarkte miokarda.