title: Application of cellulose acetate electrophoresis to globin chain separation for antenatal diagnosis of beta thalassemia.
abstract: Application of cellulose acetate electrophoresis to globin chain separation for antenatal diagnosis of beta thalassemia has been studied. A good correlation between an electrophoretic and a chromatographic method on carboxymethylcellulose was found and the diagnoses suggested by both methods were always coincident. The electrophoretic method was also utilized for HbS/beta-thalassemia diagnosis.
mesh_terms: D019411:Clinical Laboratory Techniques; D004588:Electrophoresis, Cellulose Acetate / Q000379:methods; D005260:Female; D005914:Globins / Q000302:isolation & purification*; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013789:Thalassemia / Q000175:diagnosis*
chemical_list: D006451:Hemoglobin, Sickle; D005914:Globins