Reversible hypothyroidism after steroid replacement for Addison's disease.
An insulin-requiring diabetic patient who developed Addison's disease is described. At diagnosis, investigations revealed biochemical hypothyroidism and these abnormalities resolved after replacement therapy for the adrenal failure only. The possible mechanism of this change is discussed in relation to the presence of organ-specific antibodies.
D000224:Addison Disease / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D003348:Cortisone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006650:Histocompatibility Testing; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use*; D007037:Hypothyroidism / Q000150:complications / Q000188:drug therapy*; D008297:Male
D001323:Autoantibodies; C033001:9-fluorocortisone; D003348:Cortisone; D006854:Hydrocortisone