title: DNA replications in Chironomus polytene chromosomes during treatment with ethanol.
abstract: DNA replication of Chironomus polytene chromosomes was investigated The results show that during treatment with ethanol there is an accumulation of newly synthesized DNA with the size expected of replicons. These and previous results indicate that it is possible that in polytene chromosomes the termination of replication and merging of adjacent replicons is more sensitive to damage than in initiation and/or elongation steps.
mesh_terms: D000818:Animals; D002683:Chironomidae / Q000235:genetics*; D002875:Chromosomes / Q000032:analysis / Q000187:drug effects*; D004247:DNA / Q000032:analysis; D004261:DNA Replication / Q000187:drug effects*; D004175:Diptera / Q000235:genetics*; D000431:Ethanol / Q000494:pharmacology*
chemical_list: D000431:Ethanol; D004247:DNA