title: Stress and magnesium.
abstract: The General Adaptation Syndrome is characterized by three stages: Alarm Reaction - Adaptation - Exhaustion. Results of animal experiments and clinical observations indicate that both central nervous and peripheral systemic reactions to acute stress - e.g. noise - can be accentuated by magnesium deficiency and reduced by mild hypermagnesemia, respectively. Concerning long term suboptimal magnesium supply, experimental data indicate that a stage of adaptation might be achieved during a certain period of time, preceded and followed by stages of markedly decreased resistance.U
mesh_terms: D000818:Animals; D002492:Central Nervous System Depressants / Q000494:pharmacology; D005790:General Adaptation Syndrome / Q000503:physiopathology; D006321:Heart / Q000187:drug effects; D006801:Humans; D008274:Magnesium / Q000494:pharmacology / Q000502:physiology*; D008275:Magnesium Deficiency / Q000503:physiopathology; D051381:Rats; D013312:Stress, Physiological / Q000503:physiopathology*
chemical_list: D002492:Central Nervous System Depressants; D008274:Magnesium