[Humoral immune response after splenic experimental autotransplantation in the dog (author's transl)].
Primary and secondary humoral immune responses were studied in a group of 40 dogs after splenectomy and two types of splenic autotransplantation. The results enable the authors to conclude that splenectomy alone induces a depletion of immunoglobulins which is statistically significant. On the other hand, both types of autotransplantation made possible the maintenance of normal levels of anti-BSA antibodies. When autotransplantation was performed in the abdominal rectus muscle there was an enhancement of the primary immune response. The authors advise this procedure in all splenectomies for trauma in the first five years of life.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D001706:Biopsy; D004285:Dogs; D005260:Female; D007153:Immunologic Deficiency Syndromes / Q000209:etiology; D008297:Male; D012710:Serum Albumin, Bovine / Q000276:immunology; D013154:Spleen / Q000473:pathology / Q000637:transplantation*; D013156:Splenectomy / Q000009:adverse effects; D014182:Transplantation, Autologous / Q000379:methods
D000906:Antibodies; D012710:Serum Albumin, Bovine
Respuesta inmunológica humoral en el autotrasplante esplénico. Estudio experimental en el perro.