title: The clinical application of electron microscopy and the heterologous ova penetration test to the assessment of spermatozoa from infertile men.
abstract: Ultrastructural studies of spermatozoa from men whose spermatozoa repeatedly had shown poor motility demonstrated an increase in morphological abnormalities. This was considered significant in the 8 men in whom all of the spermatozoa were abnornmal and probably significant in those where more than 90% were abnormal (9 men). Spermatozoa from 15 fertile men adhered to and penetrated 60% of hamster oocytes, whereas those from infertile men, with both normal and poor semen quality, failed to adhere or penetrate. The heterologous sperm penetration test offers a new approach to the assessment of semen quality in infertile men.
mesh_terms: D000818:Animals; D006224:Cricetinae; D005260:Female; D005306:Fertilization; D006801:Humans; D007248:Infertility, Male / Q000473:pathology*; D008297:Male; D013081:Sperm Motility; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000648:ultrastructure*