Morphine reinforces post-discharge inhibition of alpha-motoneurons in man.
Morphine chlorhydrate (0.25 mg/kg)produced a significant and constant reinforcement of post-discharge inhibition of alpha-motoneurons in both normal and paraplegic humans. This effect was reversed by naloxone hydrochloride (0.02 mg/kg). These data do not allow to differentiate the effects of morphine on recurrent inhibition and on A.H.P.
D000328:Adult; D005260:Female; D006181:H-Reflex / Q000187:drug effects; D006801:Humans; D008297:Male; D009020:Morphine / Q000494:pharmacology*; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology; D010264:Paraplegia / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000503:physiopathology
D009270:Naloxone; D009020:Morphine