Interaction of mammalian hemoglobins with dehydroascorbic acid.
Reactive sulfhydryl groups of major hemoglobins from guinea-pig, rat and cat reduced dehydroascorbic acid to ascorbic acid leading to formation of intrachain disulfide bonds. Hybridization experiments indicated that the reduction was carried out by the alpha chain of cat hemoglobin.
D000818:Animals; D001205:Ascorbic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D002415:Cats; D002417:Cattle; D003683:Dehydroascorbic Acid / Q000378:metabolism*; D004220:Disulfides / Q000378:metabolism; D004285:Dogs; D006041:Goats; D006168:Guinea Pigs; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D010084:Oxidation-Reduction; D011487:Protein Conformation; D011817:Rabbits; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism
D004220:Disulfides; D006454:Hemoglobins; D013438:Sulfhydryl Compounds; D001205:Ascorbic Acid; D003683:Dehydroascorbic Acid