[Response of the rat pituitary-adrenal system to stress during early postnatal development].
During postnatal development the reaction of hypophysial-suprarenal system of young rats to subcutaneous injection of formaldehyde and immobilization appeared earlier (on the 4th day) than that to cooling and new environment (on the 12th day). Both in 16 days old and adult rats the increase of corticosteroid level in blood in response to different stress effects was similar. A change of the intensity of cooling did not affect the reaction of hypophysial-suprarenal system of young rats. It is suggested that the absence of reaction of hypophysial-suprarenal system to some stimuli is due, during the first days after birth, to unequal functional maturity of the central mechanisms taking part in the reaction to these stimuli.
D015062:11-Hydroxycorticosteroids / Q000097:blood*; D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D003080:Cold Temperature / Q000009:adverse effects; D005260:Female; D005557:Formaldehyde / Q000506:poisoning; D008297:Male; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D051381:Rats; D012149:Restraint, Physical / Q000009:adverse effects; D013312:Stress, Physiological / Q000097:blood / Q000503:physiopathology*
D015062:11-Hydroxycorticosteroids; D005557:Formaldehyde
Reaktsiia gipofizarno-nadpochechnikovoĭ sistemy krys na stressovye vozdeĭstviia v rannem postnatal 'nom razvitii.