title: Reversible and irreversible structural modifications of erythrocyte membrane.
abstract: Membrane glycoprotein structure regulates the fate in the circulation of mammalian erythrocytes: the mechanism of this phenomenon was observed in rabbit and human red cells by in vivo and in vitro experiments. Glycoprotein remodeling can occur as a reversible desialylation process, produced by different events, or as an irreversible process consisting in a loss of sialoglycopeptides. The effect of these two phenomena on the viability of the red cell in the circulation was the subject of our investigation.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D004905:Erythrocyte Aging; D004910:Erythrocyte Membrane / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D008565:Membrane Proteins / Q000097:blood*; D011817:Rabbits; D012794:Sialic Acids / Q000097:blood; D012795:Sialoglycoproteins / Q000097:blood
chemical_list: D000596:Amino Acids; D006023:Glycoproteins; D008565:Membrane Proteins; D012794:Sialic Acids; D012795:Sialoglycoproteins