Familial 5/14 translocation with triple X and 47,XY + 14q.
A family with 5/14 balanced translocation was investigated. The father and both his daughters had the same balanced translocation. One of the daughters had four spontaneous abortions, the last one with a karyotype of 47,XY + 14q-. The other daughter had two children, one of them a normal 46,XX girl, the other with the karyotype 47,XXX;5/14.
D000026:Abortion, Habitual / Q000235:genetics; D002901:Chromosomes, Human, 13-15; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D012730:Sex Chromosomes; D014178:Translocation, Genetic; D014314:Trisomy; D014960:X Chromosome