[Quantitative analysis of lesions of the aortic and carotid artery endothelium in experimental diabetes in rabbits by scanning electron microscopy].
A significant increase in the number and zone area of argyrophil cells, craters and stomata of the intracellular formations were seen in the aortic and carotid pectoral and peritoneal regions of rabbits with 5-week alloxan diabetes. The number and zone area of vascular de-endothelization did not increase. Cell polymorphism, apart from maintenance of pronounced argyrophilia and micro-injuries, occurred to diabetes of 5-month standing. Deranged properties of the macrovascular endothelial integument may be of great importance in the pathogenesis of atheromatosis in diabetes mellitus.
D000818:Animals; D001012:Aorta, Abdominal / Q000648:ultrastructure; D001013:Aorta, Thoracic / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000473:pathology*; D002339:Carotid Arteries / Q000648:ultrastructure; D002340:Carotid Artery Diseases / Q000473:pathology*; D003921:Diabetes Mellitus, Experimental / Q000150:complications*; D003925:Diabetic Angiopathies / Q000473:pathology*; D004727:Endothelium / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D011817:Rabbits
Kolichestvennyĭ analiz povrezhdeniĭ éndotelial'nogo pokrova aorty i sonnoĭ arterii pri éksperimental'nom sakharnom diabete u krolikov metodom rastrovoĭ élektronnoĭ mikroskopii.