The effect of Trichinella spiralis on the rate of clearance of 51Cr-labelled sheep red blood cells and 125I-polyvinyl pyrrolidone from the bloodstream of mice.
Mice infected for one to eight weeks with Trichinella spiralis cleared either 51Cr-labelled sheep red blood cells (SRBC) or 125I-polyvinyl pyrrolidone (PVP) given intravenously. PVP was cleared more rapidly from the blood of mice infected for one week than from uninfected mice with older infections which behaved in a similar manner to the controls. SRBC were consistently cleared faster from the blood of mice infected for one week than from normal mice. If the infections were older than this a more rapid clearance was also demonstrated as long as the infections were reasonably heavy.
D000818:Animals; D004912:Erythrocytes; D008262:Macrophage Activation; D051379:Mice; D008815:Mice, Inbred Strains; D010587:Phagocytosis; D011205:Povidone; D012756:Sheep / Q000097:blood; D014235:Trichinellosis / Q000276:immunology*
D011205:Povidone