[Exercise-induced asthma (EIA) and radioallergosorbenttest (RAST) (author's transl)].
38 children with bronchial asthma were investigated for allergy (RAST), non-specific bronchial hyperreactivity (acetylcholine challenge) and reaction to physical exercise (free running and bicycle ergometry). 17 patients showed EIA caused by free running and 11 by cycloergometry. Patients with clear-cut allergy (n = 27, high RAST values, class 3 and 4) showed exercise-induced bronchoconstriction in a high percentage of cases (16 of 27 following running, 10 of 27 after bicycle ergometry). Such patients also had non-specific bronchial hyperreactivity. This would explain treatment failures after correctly performed specific immunotherapy.
D000109:Acetylcholine; D000293:Adolescent; D001249:Asthma / Q000175:diagnosis*; D001250:Asthma, Exercise-Induced / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D005082:Physical Exertion; D011852:Radioallergosorbent Test / Q000379:methods*; D011863:Radioimmunoassay / Q000379:methods*
D007073:Immunoglobulin E; D000109:Acetylcholine
Exercise-induced Asthma und Radioallergosorbenttest.