[Hexokinase and lactate dehydrogenase activity, lactic and pyruvic acid content of erythrocytes and acid-base equilibrium in stomach cancer patients after radical operations].
Certain glycolytic enzymes, the level of end metabolites of glycolysis and acid-base equilibrium indices were studied in 106 patients with stomach tumors (stage II-III). It was found that prior to surgery metabolic disturbances in erythrocytes are to be observed, while acid-base indices tend toward metabolic acidosis. After radical surgery, the activity levels of hexokinase and lactate, dehydrogenase as well as concentrations of lactic and pyruvic acids are decreased, acid-base equilibrium being restored much earlier.
D000136:Acid-Base Equilibrium; D000328:Adult; D000368:Aged; D004789:Enzyme Activation; D004912:Erythrocytes / Q000378:metabolism*; D005743:Gastrectomy; D006593:Hexokinase / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D008875:Middle Aged; D011184:Postoperative Period; D011773:Pyruvates / Q000097:blood*; D019289:Pyruvic Acid; D013274:Stomach Neoplasms / Q000097:blood* / Q000601:surgery
D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; D007770:L-Lactate Dehydrogenase; D006593:Hexokinase
Aktivnost' geksokinazy, laktatdegidrogenazy, soderzhanie molochnoĭ, pirovinogradnoĭ kislot v éritrostsitakh i kislotno-shchelochnoe ravnovesie u bol'nykh rakom zheludka posle radikal'nykh operatsiĭ.