Specific inactivation of aniline hydroxylase by a reactive intermediate formed during acrylamide biotransformation by rat liver microsomes.
D000178:Acrylamides / Q000378:metabolism* / Q000494:pharmacology; D000815:Aniline Hydroxylase / Q000037:antagonists & inhibitors*; D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000037:antagonists & inhibitors*; D001711:Biotransformation; D007700:Kinetics; D008297:Male; D008797:Metyrapone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats
D000178:Acrylamides; D000815:Aniline Hydroxylase; D001189:Aryl Hydrocarbon Hydroxylases; D010634:Phenobarbital; D008797:Metyrapone