title: The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC).
abstract: The influence of the amino group of guanine on the molecular electrostatic potential and the accessibility to reactive sites of B-DNA is investigated by comparing the two model double helices poly (dI.dC) and poly (dG.dC). The calculations clarify the "disruptive" role of the guanine amino group on nucleic acid-polypeptide interactions.
mesh_terms: D000494:Allosteric Regulation; D000900:Anti-Bacterial Agents; D004563:Electrochemistry; D006147:Guanine; D008956:Models, Chemical; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D011089:Polydeoxyribonucleotides; D013816:Thermodynamics
chemical_list: D000900:Anti-Bacterial Agents; D009838:Oligodeoxyribonucleotides; D009841:Oligonucleotides; D011089:Polydeoxyribonucleotides; C031156:poly d(I-C); C019530:poly(dC-dG); D006147:Guanine