The role of anticonvulsant medications in the management of patients with anaplastic gliomas.
All 100 patients in a protocol of therapy for anaplastic gliomas were studied with regard to occurrence of seizures preoperatively and postoperatively. Patients without a history of seizures preoperatively had a similar incidence of seizures postoperatively, whether anticonvulsant medications were prescribed prophylactically or not.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy*; D004311:Double-Blind Method; D005625:Frontal Lobe; D005910:Glioma / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D010672:Phenytoin / Q000627:therapeutic use; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control; D012640:Seizures / Q000517:prevention & control
D000927:Anticonvulsants; D010672:Phenytoin