Histological and stereological analysis of microinvasive carcinoma of the uterine cervix.
To estimate the size of microinvasive carcinoma, stereological analysis proved to be an appropriate objective method. The difference between reticular and droplike pattern of invasion was presented by calculation of the absolute surface and the factor of deformity. Zeiss's light microscope at 100 X magnification and Weibel's multipurpose test system were used for the investigation of 14 cases of microinvasive carcinoma. High significant correlation was established between the pattern of invasion, the presence of vascular spread, and the stereological findings, indicating that in microcarcinoma with reticular pattern of invasion increasing values of the absolute surface and the factor of deformity could signify a greater degree of tumour invasiveness.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D002583:Uterine Cervical Neoplasms / Q000473:pathology*