Distribution of long chain polyenoic acids among phospholipids of mouse testis.
Fatty acid composition of phospholipid (PL) classes was measured in mouse testis. Among the long-chain polyenoic acids (LCPA), 22:6 was found in highest concentration in phosphatidylethanolamine (PE), whereas percentages of 20:4 and 22:5 were not different in PE than in phosphatidycholine. Each PL class had a unique fatty acid composition which was also different from that of triglycerides and cholesteryl esters. Differential metabolisms of 22:5 and 22:6 suggest different roles for these fatty acids in mouse testis. Tissue-specific functions of LCPA in mouse spermatogenesis may be divided between 22:5 and 22:6.
D000818:Animals; D005227:Fatty Acids / Q000378:metabolism*; D008244:Lysophosphatidylcholines / Q000378:metabolism; D008297:Male; D051379:Mice; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism; D010718:Phosphatidylserines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*
D005227:Fatty Acids; D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010718:Phosphatidylserines; D010743:Phospholipids