A rat model of the fetal alcohol syndrome--preliminary histological findings.
A semipurified liquid diet was used to develop a chronic rat model of fetal alcohol syndrome. Adult female rats were fed a control or 40% ethanol (percent of total caloric intake) liquid diet. Additional controls were pair fed to the 40% experimental group. Results of the effects of these diets on the offspring included both qualitative and quantitative changes observed in Golgi study of hippocampal pyramidal neurons.
D000818:Animals; D001724:Birth Weight / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D003712:Dendrites / Q000473:pathology; D004195:Disease Models, Animal; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000401:mortality / Q000473:pathology*; D006624:Hippocampus / Q000473:pathology; D008098:Litter Size; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats