[Role of immune and normal sera in protection from ozena].
For the first time high preventive properties of sera obtained from ozena patients and healthy persons have been established on the model of acute ozena sepsis. The preventive properties of sera obtained from ozena patients and containing antibodies to the somatic antigens of the causative agent of ozena (O-antibodies) are higher than those of sera obtained from healthy persons. But this effect is linked not with O-antibodies, but probably with the presence of antibodies to the capsular antigen of the microbe (C-antibodies), which are not detected in the agglutination test. The indirect proof of the presence of C-antibodies in the sera of ozena patients, containing O-antibodies, have been obtained due to the ability of C-antibodies to enhance in vivo and to decrease in vitro the bactericidal activity of sera obtained from such patients.
D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology; D003168:Complement Fixation Tests; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage / Q000276:immunology; D007116:Immunization, Passive; D007709:Klebsiella / Q000276:immunology; D011817:Rabbits / Q000276:immunology; D012222:Rhinitis, Atrophic / Q000517:prevention & control*
D000907:Antibodies, Bacterial; D007106:Immune Sera
Rol' immunnykh i normal'nykh syvorotok v zashchite ot ozenoznoĭ infektsii.