title: Prednisone increases the number of insulin receptors on monocytes from normal subjects.
abstract: The effect of prednisone on insulin receptors on circulating monocytes was studied in 38 normal volunteers. Intake of prednisone in doses which are usually employed in clinical treatment (40 mg/day) was associated with a significant increase int the number of insulin receptors. The rise in insulin binding was maximal 7 h after the begining of the medication and it was dose related.
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D007657:Ketone Bodies / Q000097:blood; D007700:Kinetics; D008297:Male; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism*; D011241:Prednisone; D011972:Receptor, Insulin / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D007328:Insulin; D007657:Ketone Bodies; D011972:Receptor, Insulin; D011241:Prednisone