[Selective IgA deficiency in systemic lupus erythematosus (author's transl)].
The case of a 23 year-old female with a diagnosis of systemic lupus erythematosus associated to selective IgA deficiency is reported. The patient persistently had serum IgA levels below 0.05 mg/dl, while the remaining serum immunoglobulins were normal. No salivary IgA was detected, and the karyotype disclosed no abnormalities of the chromosome 18. In the in vitro immunological study a normal number of B and T lymphocytes was found, and decreased production of all surface immunoglobulins was observed.
D000328:Adult; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D007070:Immunoglobulin A / Q000235:genetics; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000276:immunology* / Q000652:urine; D012463:Saliva / Q000276:immunology
D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory
Deficiencia selectiva de IgA en el lupus eritematoso sistémico.