title: Structure of filamentous bacteriophage: isolation, characterization, and localization of the minor coat proteins and orientation of the DNA.
abstract: The minor coat proteins of the filamentous bacteriophage fl and fd have been isolated and characterized. The phage have approximately 5 copies each of the A protein (product of gene III) and  the D protein (product of gene VI). The phage also contains about 10 copies of the C protein. Preliminary evidence suggests that the "C protein" may actually be a mixture of proteins, the major component of which is the product of gene IX. The D protein is located near or at the A protein end of the phage, and the C protein is located in a region near or at the other end. The DNA appears to be oriented iun the virion such that the DNA which specifies the intergenic region is located close to the C protein end of the phage and that which codes for the gene III protein is located near the A and D protein end.
mesh_terms: D001665:Binding Sites; D003090:Coliphages / Q000648:ultrastructure*; D004279:DNA, Viral / Q000378:metabolism; D008854:Microscopy, Electron; D008970:Molecular Weight; D011485:Protein Binding; D014764:Viral Proteins / Q000302:isolation & purification / Q000378:metabolism*; D014779:Virus Replication
chemical_list: D004279:DNA, Viral; D014764:Viral Proteins