Purification and characterization of a haptoglobin-hemoglobin complex isolated from human fetuses.
A haptoglobin-hemoglobin complex was purified from human fetuses (10-week-old pregnancies). The yield was 12% and the purification factor was about 450. The purified complex appears to have a molecular weight of 850,000 daltons. It cross-reacts with human adult haptoglobins. Its electrophoretic mobility was reduced from alpha 2- to beta-globulin when compared with the adult molecule.
D005260:Female; D005333:Fetus / Q000032:analysis*; D006242:Haptoglobins / Q000276:immunology / Q000302:isolation & purification*; D006454:Hemoglobins / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D011247:Pregnancy
D006242:Haptoglobins; D006454:Hemoglobins