Role of nutrients in the gastrointestinal release of immunoreactive neurotensin.
Neurotensin is a brain-gut tridecapeptide. It can be released into the circulation upon ingestion of a meal, or when the jejuno-ileal segment of the human gut is exposed to a mixed meal. Among the various constituents of the products of food digestion, fatty acid is the most potent in stimulating immunoreactive neurotensin release. This response is dose dependent. The physiological role of postprandial changes of circulating neurotensin needs further elucidation.
D004041:Dietary Fats / Q000008:administration & dosage; D004064:Digestive System / Q000187:drug effects; D004068:Digestive System Physiological Phenomena; D005227:Fatty Acids / Q000494:pharmacology; D005502:Food; D006801:Humans; D007082:Ileum / Q000502:physiology; D007583:Jejunum / Q000502:physiology; D009496:Neurotensin / Q000097:blood*; D019301:Oleic Acid; D009829:Oleic Acids
D004041:Dietary Fats; D005227:Fatty Acids; D009829:Oleic Acids; D019301:Oleic Acid; D009496:Neurotensin