[Modifications of pure pancreatic secretion in patients with chronic renal failure treated by hemodialysis (author's transl)].
In 20 patients suffering from chronic renal failure treated by hemodialysis (CRFH) the pure pancreatic juice (PPJ) collected via endoscopic cannulation of the papilla was studied. PPJ was collected during 20 minutes in 1 minute samples. Secretin and pancreozymin (CCK-PZ) were given as boluses respectively at the beginning and at the 10th minute of the test. Volumes, total protein and bicarbonate concentrations, total protein and bicarbonate outputs, Lactoferrin (LF) levels were measured. The results observed in patients were compared to those of ten subjects free of any organic disease. The volume of PPJ was significantly more important in CRFH than in controls. Bicarbonate and protein concentrations were not significantly modified. Protein output was not significantly more important in CRFH at the exception of the 12th sample. Bicarbonate output was not significantly increased at the exception of the 9th and the 11th samples. LF level was more than 0.03% of total proteins in 4 CRFH.
D000328:Adult; D001639:Bicarbonates / Q000032:analysis; D002766:Cholecystokinin; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy; D007781:Lactoferrin / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000378:metabolism*; D010189:Pancreatic Juice / Q000032:analysis; D011506:Proteins / Q000032:analysis; D006435:Renal Dialysis; D012633:Secretin
D001639:Bicarbonates; D011506:Proteins; D012633:Secretin; D002766:Cholecystokinin; D007781:Lactoferrin
Modifications de la sécrétion pancréatique pure chez les patients atteints d'insuffisance rénale chronique traités par hémodialyse.