Estimate of the risk of post transfusion hepatitis B in Jakarta, Indonesia.
The prevalences of hepatitis B surface antigen (HBsAg) and antibody to HBsAg (anti-HBs) were determined in blood donors and transfusion recipients in Jakarta, Indonesia. In blood donors the prevalence of HBsAg was 10% while anti-HBs was 43%. In transfusion recipients the prevalence of HBsAg and anti-HBs was 67%. The prevalence of susceptible recipients or those without detectable HBsAg or anti-HBs was 33%. Thus, the probability that a susceptible recipient would receive HBsAg from a blood donor was calculated at 3.3%. Published data from other studies were used to estimate the risk of clinical post transfusion hepatitis in Jakarta at between 0% and 2%.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D001782:Blood Donors; D002648:Child; D002675:Child, Preschool; D006509:Hepatitis B / Q000635:transmission*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D007214:Indonesia; D008297:Male; D008875:Middle Aged; D012306:Risk; D065227:Transfusion Reaction
D000914:Antibodies, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens