Steady state drug or fluid delivery to injured or transected spinal cord of rats.
Fluids or drugs were delivered to injured or transected spinal cords of rats at a controlled rate and concentration. The technique used a catheter system molded to the shape of the spinal cord and attached to an osmotic minipump reservoir that was subcutaneously by the rats.
D000818:Animals; D002404:Catheterization; D005070:Evans Blue; D008297:Male; D010477:Perfusion / Q000295:instrumentation / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D011182:Postoperative Care; D019736:Prostheses and Implants; D051381:Rats; D013116:Spinal Cord / Q000098:blood supply; D013119:Spinal Cord Injuries / Q000628:therapy*
D004364:Pharmaceutical Preparations; D005070:Evans Blue