Differentiation and myelination of transplanted mouse dorsal root ganglia.
Dorsal root ganglia from newborn mice develop and myelinate following transplantation under the kidney capsule of adult syngeneic mice. The transplanted dorsal root ganglia in the subcapsular environment developed more rapidly and formed more abundant myelin than comparable ganglia in an in vitro culture.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D002454:Cell Differentiation; D046508:Culture Techniques; D005727:Ganglia, Spinal / Q000254:growth & development* / Q000637:transplantation / Q000648:ultrastructure; D007668:Kidney / Q000033:anatomy & histology; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure