title: Isolated metastasis to the optic nerve.
abstract: A case of isolated optic nerve metastasis from breast carcinoma is described. Intraocular tumor was discovered three months following a radical mastectomy and was confined to the optic nerve head and distal optic nerve. Following X-irradiation treatment, central retinal vascular occlusion, rubeosis, and neovascular glaucoma developed during the fifteen months before enucleation. The clinicopathologic features of this case are discussed and the literature reviewed.
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms; D002277:Carcinoma / Q000473:pathology / Q000556:secondary*; D005123:Eye / Q000473:pathology; D005134:Eye Neoplasms / Q000473:pathology / Q000556:secondary*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000473:pathology; D009901:Optic Nerve Diseases / Q000209:etiology* / Q000473:pathology