Chemotherapy of Babesia felis infection: efficacy of certain drugs.
The efficacy of 10 drugs was tested against Babesia felis infection in domestic cats. Primaquine phosphate administered per os or as an intramuscular injection was found to be highly effective and the obvious drug of choice when compared with conventional babesicides. The recommended dosage is 0,5 mg/kg body mass of primaquine base. Repeated treatments are well tolerated but single doses in excess of 1 mg/kg are known to cause mortality in cats.
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001404:Babesiosis / Q000188:drug therapy*; D001550:Benzamidines / Q000627:therapeutic use; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D002738:Chloroquine / Q000627:therapeutic use; D004341:Drug Evaluation / Q000662:veterinary; D010647:Phenyl Ethers / Q000627:therapeutic use; D011319:Primaquine / Q000627:therapeutic use; D011806:Quinolinium Compounds / Q000627:therapeutic use; D014508:Urea / Q000031:analogs & derivatives / Q000627:therapeutic use
D000981:Antiprotozoal Agents; D001550:Benzamidines; D010647:Phenyl Ethers; D011806:Quinolinium Compounds; C005402:phenamidine isethionate; D002738:Chloroquine; D014508:Urea; C009154:quinuronium sulfate; D011319:Primaquine