Some observations on the pathogenesis of syringomyelia.
The pathogenesis of most cases of syringomyelia remains obscure although a modification of the hydrodynamic theory of Gardner allows a logical surgical approach to treatment. Data are presented confirming a high incidence of traumatic birth in patients with syringomyelia who have a Chiari malformation or basal arachnoiditis, but demonstrating no increase in traumatic birth in patients with the Chiari malformation but no syringomyelia. A traumatic birth may be the factor responsible for creating the potential for syringomyelia in those individuals with the embryological defect of the Chiari anomaly.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001100:Arachnoiditis / Q000150:complications; D001139:Arnold-Chiari Malformation / Q000150:complications; D001720:Birth Injuries / Q000150:complications; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D007744:Obstetric Labor Complications; D011247:Pregnancy; D013595:Syringomyelia / Q000209:etiology*