The Lud cold agglutinin: a further antibody recognizing N-acetylneuraminic acid-determined antigens not fully expressed at birth.
From a patient, a new type of human cold aggluntinin, Lud, which reacts with a determinant involving N-acetylneuraminic acid and which is not fully expressed at birth, is described. This antibody differs from a recently described cold agglutinin, Fl. The antigenic determinant recognized by antibody Lud is diminished after treatment of erythrocytes with proteases, whereas that recognized by Fl is not.
D000373:Agglutinins / Q000276:immunology; D000937:Antigen-Antibody Reactions; D001323:Autoantibodies / Q000276:immunology*; D003080:Cold Temperature; D005312:Fetal Blood / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D007048:I Blood-Group System / Q000276:immunology; D007231:Infant, Newborn; D009439:Neuraminidase / Q000494:pharmacology; D012794:Sialic Acids / Q000276:immunology*
D000373:Agglutinins; D001323:Autoantibodies; D007048:I Blood-Group System; D012794:Sialic Acids; D009439:Neuraminidase