In vitro effect of tetanus toxin on GABA release form rat hippocampal slices.
Ca2+-dependent K+-stimulated gamma-aminobutyric acid release from rat hippocampal slices was reduced about 30% by pre-incubation of the slices with 10(4) mouse LD50/ml tetanus toxin for 3 h at 37 degrees C.
D000818:Animals; D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D011188:Potassium / Q000494:pharmacology; D051381:Rats; D013744:Tetanus Toxin / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D013744:Tetanus Toxin; D005680:gamma-Aminobutyric Acid; D011188:Potassium