Immunoglobulins in the cerebrospinal fluid of patients with Guillain-Barré syndrome.
Increased immunoglobulin levels in the cerebrospinal fluid of patients with Guillain-Barré syndrome were found in association with increased protein levels. Evaluation of the immunoglobulin/protein ratios led us to conclude that the increase in immunoglobulin levels may be due to a leakage of plasma proteins and is unlikely to be caused by a local immune response to a preceding antigenic stimulus.
D001812:Blood-Brain Barrier; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D006801:Humans; D007070:Immunoglobulin A / Q000134:cerebrospinal fluid; D007072:Immunoglobulin D / Q000134:cerebrospinal fluid; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid; D007136:Immunoglobulins / Q000134:cerebrospinal fluid*; D011129:Polyradiculoneuropathy / Q000134:cerebrospinal fluid*; D013997:Time Factors
D002556:Cerebrospinal Fluid Proteins; D007070:Immunoglobulin A; D007072:Immunoglobulin D; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins