Antibody-induced redistribution and shedding of membrane proteins in Duchenne muscular dystrophy lymphocytes.
Surface redistribution of molecules induced by specific antibody interaction was monitored by HLA antigen "lysostrip" experiments and "shedding" of Ig surface molecules, both in Duchenne Muscular Dystrophy patients and in normal controls. No significant difference in the rate of disappearance of the proteins for the lymphocyte surface was observed between patients and controls.
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology*; D006041:Goats / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D009136:Muscular Dystrophies / Q000276:immunology*; D011947:Receptors, Antigen, B-Cell / Q000032:analysis*
D000961:Antilymphocyte Serum; D006680:HLA Antigens; D011947:Receptors, Antigen, B-Cell