[Neurochemical data concerning glial tumors. Contribution of the estimation of the G.F.A. protein to the diagnosis and prognosis of gliomas (author's transl)].
The Glial Fibrillary Acidic (G.F.A.) protein is a specific component of the gliofilaments present in the astrocytes. Its immunochemical determination on tumor fragments obtained at surgery has permitted to draw clinico-biochemical correlations between the G.F.A. content of a glioma and its histological grade. The more a glioma is dedifferentiated, the lower is its content of G.F.A. This determination is a biochemical index of dedifferentiation. However, its pronostic value is not established yet.
D001253:Astrocytes / Q000032:analysis*; D005904:Glial Fibrillary Acidic Protein; D005910:Glioma / Q000032:analysis*; D009363:Neoplasm Proteins / Q000032:analysis*; D009419:Nerve Tissue Proteins / Q000032:analysis*; D011379:Prognosis
D005904:Glial Fibrillary Acidic Protein; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins
Données neurochimiques sur les tumeurs gliales. Apports du dosage de la protéine gliofibrillaire au diagnostic et au pronostic des gliomes.