[Must renal biopsy be still performed in "lipoid nephrosis"? (author's transl)].
In 52 out of 272 children with one of the following diseases: nephrotic or nephritic syndrome, persistent humaturia and/or proteinuria, renal biopsy was performed on the basis of commonly accepted indications. 18 biopsies were from patients with a clinical picture of lipoid nephrosis and clinical course of "non responders" or "frequent relapsers" types. All of them showed the histologic pattern of minimal changes and had a value of Y index according to ISKCD greater than 0,85. Moreover all patients with minimal changes nephrotic syndrome had a Y index greater than 0.85. If these observations will be confirmed renal biopsy would not later be indicated in children with "lipoid nephrosis".
D001706:Biopsy; D006417:Hematuria / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology*; D009393:Nephritis / Q000175:diagnosis; D009402:Nephrosis, Lipoid / Q000175:diagnosis*; D009404:Nephrotic Syndrome / Q000175:diagnosis; D011507:Proteinuria / Q000175:diagnosis
Esiste ancora indicazione all biopsia renal nella "nefrosi lipoidae"?