title: The effects of prolonged exercise on spinally injured subjects.
abstract: The effects of prolonged exercise on paraplegics have not been reported. Seven male paraplegic subjects with spinal lesions from T4 - T12 - L1 underwent an incremental wheelchair treadmill test to exhaustion. Heart rate (HR), VO2max, and VESTPD were recorded and calculated. One week later, subjects exercised in their wheelchairs at approximately 50% (mean = 52 +/- 2%) of VO2max for 60 min on a motorized treadmill. Approximately 10 ml venous blood was withdrawn both 10 min and immediately prior to the prolonged exercise, at 20, 40, and 60 min of the exercise period, and at 10 min post-exercise. Venous blood was analyzed for glucose, hemoglobin, lactate, Na+, K+, Cl-, and plasma protein. Hematocrit was recorded and plasma volume changes calculated VO2, VE, and HR were recorded at 17, 37, and 57 min of the prolonged exercise. The mean VO2max was 29.5 +/- 2.7 ml.kg-1.min-1, with a mean max VESTPD and HR of 61.86 +/- 4.98 1.min-1 and 174 +/- 4 b.min-1, respectively. The changes in VO2 and VE during the prolonged wheelchair exercise were not significant. Significant changes occurred in venous lactate and plasma glucose concentrations during prolonged wheelchair exercise. Plasma volume changes were similar to those seen in able-bodied subjects. A notable finding was the pre-exercise hemodilution. Present data indicate that paraplegics can exercise at approximately 50% VO2 for 60 min, producing responses similar to those in able-bodied subjects.
mesh_terms: D000328:Adult; D005541:Forced Expiratory Volume; D006339:Heart Rate; D006801:Humans; D007773:Lactates / Q000097:blood; D008297:Male; D010101:Oxygen Consumption; D010264:Paraplegia / Q000378:metabolism / Q000503:physiopathology* / Q000534:rehabilitation; D005082:Physical Exertion; D010953:Plasma Volume; D013997:Time Factors
chemical_list: D007773:Lactates