Absorption of amino acids in different parts of the small intestine in growing pigs. I. Absorption of free amino acids and water.
The study was on pigs weighing 50-75 kg with temporarily isolated loops of the proximal, middle and terminal small intestine. Isolated segments were perfused with solutions of acid hydrolysate of casein containing 8, 12 or 16 g free amino acids per litre. The capacity to absorb water increased along the small intestine reaching about 5 1/m/24 h in the distal part. The absorption of nitrogen from all solutions was least in the proximal small intestine (up to 8 g/m/24 h); there were no significant difference in nitrogen absorption between the other parts. The rates of absorption of various amino acids, were different and depended on the concentration of amino acids in the intestine. On the whole, the rates of absorption of essential amino acids were: Arg, Met, Ile, Leu greater than lys greater than Thr, His. From among the non-essential amino acids Glu and Gly were absorbed to the lesser extent than the other ones.
D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D013552:Swine / Q000378:metabolism*; D013997:Time Factors; D014867:Water / Q000378:metabolism*
D000596:Amino Acids; D014867:Water; D009584:Nitrogen