title: [Clinical, morphological and biochemical changes in pigs caused by the toxic metabolites of Fusarium tricinctum].
abstract: Experiments were carried out with pigs in the course of 30 days with the use of dietary mixtures containing 10 and 20 per cent cultures of Fusarium tricinctum in rice. The treated animals showed higher sensitivity to trichotecenes. These moulds metabolites raised the activity of the serum glutamate oxaloacetate and glutamate-pyruvate transaminases, aldolase, lactate dehydrogenases, alkaline phosphatase, lipid level, and leukocyte count but lowered the amount of total protein and that of hemoglobin. The morphologic lesions seemed confined mainly to the stomach, intestines, and kidneys.
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000187:drug effects; D005260:Female; D008297:Male; D012717:Sesquiterpenes / Q000633:toxicity*; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000139:chemically induced* / Q000473:pathology; D013605:T-2 Toxin / Q000633:toxicity*; D014255:Trichothecenes / Q000633:toxicity*
chemical_list: D012717:Sesquiterpenes; D014255:Trichothecenes; D013605:T-2 Toxin
vernacular_title: Klinichni, morfologichni i biokhimichni promeni pri praseta, predizvikani ot toksichni metaboliti na Fusarium trichinatum.