Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites.
D000082:Acetaminophen / Q000009:adverse effects / Q000378:metabolism; D000478:Alkylation; D000818:Animals; D055598:Chemical Phenomena; D056486:Chemical and Drug Induced Liver Injury; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D004980:Ethane / Q000009:adverse effects; D005978:Glutathione / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D051379:Mice; D010420:Pentanes / Q000009:adverse effects; D010545:Peroxides / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000032:analysis
D010420:Pentanes; D010545:Peroxides; D004364:Pharmaceutical Preparations; D010713:Phosphatidylcholines; D000082:Acetaminophen; D005978:Glutathione; D004980:Ethane