title: Trichinella spiralis in rats: in vivo effects of the bile and in vitro action of secretory IgA from bile.
abstract: The biliary secretion of rats is diverted from the choledoch duct to the bladder. These rats are resuscitated by sub-cutaneous injections of a salt solution and then infected with Trichinella spiralis larvae. It is shown that the number of adult worms is increased (+ 66%); as is the female larvae production (+ 51%); the females' length is also increased (+ 25%). 40 days after the infection the number of muscular larvae is considerably increased (+ 79%) in comparison with control rats. Secretory IgA (SIgA) from rats bile were tested in vitro on the female production of larvae. This larvae production was more inhibited (59%) by immune SIgA than by control SIgA (25%).
mesh_terms: D000818:Animals; D001646:Bile / Q000276:immunology / Q000502:physiology*; D007070:Immunoglobulin A / Q000502:physiology*; D007071:Immunoglobulin A, Secretory / Q000502:physiology*; D009132:Muscles / Q000469:parasitology; D051381:Rats; D011919:Rats, Inbred Strains; D014234:Trichinella / Q000254:growth & development*; D014235:Trichinellosis / Q000469:parasitology*
chemical_list: D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory