[Comparison of the antimicrobial properties of catamin AB and rockal and their action on bacterial membrane systems].
The antimicrobial properties of two cationic detergents, i.e. rockal, an antiseptic made in England and catamine AB, its analog made in the USSR were compared. It was found that catamine AB and rockal did not practically differ by their bacteriostatic and mycostatic activities with respect to collection and clinical strains of bacteria with multiple resistance to antibiotics. Both detergents were shown to be identical by their membranotropic activity and thus catamine AB may be used instead of rockal as an antiseptic.
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000648:ultrastructure; D002462:Cell Membrane / Q000187:drug effects; D005658:Fungi / Q000187:drug effects / Q000648:ultrastructure; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D013501:Surface-Active Agents / Q000494:pharmacology*; D013997:Time Factors
D000891:Anti-Infective Agents, Local; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; C031490:catamine AB; C017005:Rockal
Sravenenie antimikrobnykh svoĭtsv katamina AB i ikh deĭstvie na membrannye sistemy bakteriĭ.