[Chorea and chloroquine. A new treatment for an ancient malady].
Chloroquine is a drug used mainly as an anti-malaria agent with many other pharmacological properties. It was given to a patient with chorea and disseminated lupus erytematosus seeking the anti-inflammatory effect of the drug. The unexpected result on chorea hastened its use in 7 other patients with the same success. Chloroquine seems to be an effective drug for the relief of chorea. The mechanism of action is unknown.
D000293:Adolescent; D000328:Adult; D002648:Child; D002738:Chloroquine / Q000627:therapeutic use*; D002819:Chorea / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy; D008297:Male; D012214:Rheumatic Heart Disease / Q000188:drug therapy
D002738:Chloroquine
Corea y cloroquina. Un nuevo tratamiento para un antiguo mal.