[Induced leukemias. Cytogenetical and cytological aspects. Comparison with primitive leukemias (author's transl)].
25 presumably induced leukemias, either following treatment (lymphoma, polycythemia vera, essential thrombocythemia, cancers) or after exposure to oncogenic agents have been studied cytogenetically and cytologically. Complex chromosomal abnormalities were associated with a difficult cytological classification. Complete monosomy 7 with presence of micromegacaryocytes and macroplatelets was observed in 7 cases. The findings observed in induced leukemias were compared with those found in "primitive" leukemias showing the same chromosomal patterns. The same relationships between cytology and cytogenetics have been observed.
D000328:Adult; D000368:Aged; D002648:Child; D002869:Chromosome Aberrations; D002905:Chromosomes, Human, 4-5; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D007223:Infant; D007938:Leukemia / Q000139:chemically induced / Q000235:genetics* / Q000473:pathology; D007953:Leukemia, Radiation-Induced / Q000235:genetics; D008297:Male; D008875:Middle Aged
Leucémies "induites". Aspects cytogénétique et cytologique. Comparaison avec des leucémies primitives.