General model for dissolution rates of n-component, nondisintegrating spheres.
The dissolution rates of compressed spheres consisting of two and three components were measured. A general model for dissolution rates of n-component, nondisintegrating spheres is discussed. Experimental cases are presented to support the model for two- and three-component spheres, two-component interacting spheres, and three-component spheres containing two components that complex.
D001241:Aspirin; D002110:Caffeine; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004338:Drug Combinations; D007700:Kinetics; D008956:Models, Chemical; D010615:Phenacetin; D012459:Salicylates; D020156:Salicylic Acid; D012995:Solubility
D004338:Drug Combinations; D012459:Salicylates; D002110:Caffeine; D010615:Phenacetin; D020156:Salicylic Acid; D001241:Aspirin