[Hypophosphatemic coma (author's transl)].
A 4-3/12 old boy with a hypophosphoremic coma (serum phosphorus: 0.4 mg./dl.) is presented. The favoring conditions appear to be related to acute renal failure in polyuric phase with high phosphorus excretion, low phosphorus intake, rapid transit from a catabolic to an anabolic state with previous malnutrition and parenteral feeding, oral aluminum hydroxide gel administration and lung infectious disease. The clinical, biochemical data, evolution and physiologic mechanisms are commented, specially those of erythrocyte, leucocyte and platelet disfunction related to ATP, AMP and 2.3 DPG deficiency. Proteinuria and hematuria during phosphorus depletion are emphasized. The alarm symptoms and treatment are indicated.
D058186:Acute Kidney Injury / Q000150:complications* / Q000378:metabolism; D000536:Aluminum Hydroxide / Q000009:adverse effects; D002675:Child, Preschool; D003128:Coma / Q000209:etiology*; D006801:Humans; D007014:Hypophosphatasia / Q000150:complications*; D008297:Male; D010710:Phosphates / Q000378:metabolism; D013921:Thrombocytopenia / Q000209:etiology
D010710:Phosphates; D000536:Aluminum Hydroxide
Coma hipofosforémico.