Liver disease induced by perhexiline maleate.
This paper reports a case of fatal perhexiline maleate liver injury. A 62-year-old man had received perhexiline maleate for 18 months before death. Hepatic failure developed after a routine surgical procedure. The clinical course and histological findings are presented.
D000787:Angina Pectoris / Q000188:drug therapy / Q000201:enzymology; D056486:Chemical and Drug Induced Liver Injury; D006801:Humans; D008099:Liver / Q000201:enzymology / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000201:enzymology / Q000473:pathology; D008107:Liver Diseases / Q000201:enzymology / Q000401:mortality; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000201:enzymology / Q000601:surgery; D010480:Perhexiline / Q000009:adverse effects*; D010880:Piperidines / Q000009:adverse effects*; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D000637:Transaminases / Q000097:blood
D010880:Piperidines; D000637:Transaminases; D010480:Perhexiline