The use of megestrol acetate in some feline dermatological problems.
Twenty-one cats were treated with megestrol acetate because they were showing clinical signs associated with one of the following problems: eosinophilic ulcer, eosinophilic plaque, neurodermatitis, endocrine alopecia and miliary dermatitis. The dosage schedule was 5 mg orally per day per cat for seven days, then 5 mg every three days for 21 days. In all cats, we noted a good improvement of the lesions as soon as treatment was started. In 25% of the patients, one treatment schedule was sufficient to control the skin disease for at least 18 months. In the remaining 75%, two treatment schedules and/or a maintenance dosage had to be established.Side effects encountered were increased appetite, personality changes and depression.
D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004341:Drug Evaluation / Q000662:veterinary; D005260:Female; D008297:Male; D008535:Megestrol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019290:Megestrol Acetate; D012871:Skin Diseases / Q000188:drug therapy / Q000662:veterinary*
D003879:Dermatologic Agents; D008535:Megestrol; D019290:Megestrol Acetate