[DNCB-skin specimens for immunodiagnosis].
By epicutaneous skin test by means of 1-monochlorine-2,4-dinitrobenzene (DNCB) the primary cell-conditioned immunity is induced and is provable by the allergic skin reaction of late type. The examination of 125 clinically healthy persons of either sex at the age of 17-57 years confirms the suitability of self-produced, welded into foil skin test plasters layered with DNCB in various stages of concentration for clinical use. A 48-hour skin contact with 0.049 molar DNCB-solution (1,000 microgram DNCB: 100 microliter Ol. oliv.) leads to a late reaction in 84% of the cases, in the repeated case in 98% of the cases. The valuation of the eczema-typical symptoms is suitable for the characterization and quantification. There were no differences in age and sex. Ultrastrong reactions were not registered.
D000293:Adolescent; D000328:Adult; D004137:Dinitrochlorobenzene / Q000276:immunology*; D004485:Eczema / Q000276:immunology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D009578:Nitrobenzenes / Q000276:immunology*; D011933:Reagent Kits, Diagnostic; D012882:Skin Tests / Q000379:methods* / Q000592:standards
D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes; D011933:Reagent Kits, Diagnostic
DNCB-Hautproben zur Immundiagnostik.