[Study of regulation of orthomyxovirus virus-specific polypeptides using the ts-mutant of fowl plague virus having a transcription abnormality as a model].
The synthesis of virus-specific polypeptides in cells infected with a ts-mutant of fowl plague virus with disturbed process of secondary transcription was studied. Synthesis of all virus-specific proteins was shown to occur under conditions providing for synthesis of polyA+ cRNA at the stage of primary transcription but with disturbance of the secondary transcription and blocking of polyA- cRNA and vRNA synthesis. No time regulation of virus-specific polypeptide synthesis was in effect.
D009980:Influenza A virus / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D010452:Peptide Biosynthesis; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000096:biosynthesis*
D014764:Viral Proteins
Izuchenie reguliatsii virusspetsificheskikh polipeptidov ortomiksovirusov na modeli ts-mutanta virusa chumy, imeiushchego narushenie protsessa transkriptsii.