Radioprotective and haemopoietic effects of some lipopolysaccharides from Rhodospirillaceae species in mice.
Lipopolysaccharides (LPS) from various Rhodopseudomonas and Rhodospirillum species were tested for their radioprotective efficiency against X-irradiation and for their influence on the growth of spleen colony forming units (CFU-s) in mice. The LPS from Rhodopseudomonas gelatinosa Dr2 gave a high survival rate. It also favoured CFU-s formation and erythroid differentiation.
D000818:Animals; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000187:drug effects / Q000528:radiation effects*; D006412:Hematopoietic Stem Cells / Q000187:drug effects / Q000502:physiology; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011835:Radiation Protection; D011837:Radiation-Protective Agents; D012241:Rhodopseudomonas / Q000276:immunology*; D012246:Rhodospirillum / Q000276:immunology*; D013045:Species Specificity
D008070:Lipopolysaccharides; D011837:Radiation-Protective Agents