title: Decreased complement activity after bilateral renal ischemia in rats.
abstract: The bilateral occlusion of the renal arteries for 2h resulted in a marked decrease of serum complement activity after recirculation. The release of a proteinic factor with anticomplementary activity detectable in vitro in normal kidney supernate is considered a probable cause of the phenomenon. This factor is able to activate the alternative complement pathway in human serum.
mesh_terms: D000818:Animals; D003169:Complement Inactivator Proteins / Q000302:isolation & purification / Q000378:metabolism; D003170:Complement Pathway, Alternative; D003165:Complement System Proteins / Q000378:metabolism*; D007511:Ischemia / Q000276:immunology*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D003169:Complement Inactivator Proteins; D003165:Complement System Proteins