Biliary excretion of tartrazine in obesity.
In a continuation of studies on the metabolism of foreign compounds under the influence of diet or other factors in relation to neoplasia development, male and female weanling rats, in-bred Wistar-derived rats (50-60 g) free from disease or infection were obesified with N, N-bis (B-chloroethyl)-4, 4-bipiperidine (BPN) prior to determining the biliary excretion of tartrazine. Obese and normal animals excreted the dye unchanged and in sex-related proportions.
D000818:Animals; D001391:Azo Compounds / Q000378:metabolism*; D001646:Bile / Q000378:metabolism*; D005260:Female; D008297:Male; D008970:Molecular Weight; D009765:Obesity / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D013645:Tartrazine / Q000378:metabolism*; D013997:Time Factors
D001391:Azo Compounds; D013645:Tartrazine