title: [Metabolism of sialocontaining glycoproteins and lysosomal enzyme activity and neurotropic effect of various environmental chemical factors].
abstract: A comparative biochemical study of the sialocontaining glycoproteids metabolism and the activity of certain lysosome enzymes shows that the effect of different environmental, chemical factors (carbon disulphide, dimethyl acetamide, lead acetate; etc.) causes changes in the activity of certain lysosome enzymes and the enzyme-substrate system of N-acetyl neuraminic acid--N-acetyl neuraminic acid aldolase, participating, in the metabolism of sialocontaining glycoproteids as structural components of the brain biomembranes.
mesh_terms: D000081:Acetamides / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000201:enzymology; D002246:Carbon Disulfide / Q000494:pharmacology; D007700:Kinetics; D007854:Lead / Q000494:pharmacology; D008247:Lysosomes / Q000201:enzymology*; D009942:Organometallic Compounds; D007652:Oxo-Acid-Lyases / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D012795:Sialoglycoproteins / Q000378:metabolism*
chemical_list: D000081:Acetamides; D009942:Organometallic Compounds; D012795:Sialoglycoproteins; D007854:Lead; D007652:Oxo-Acid-Lyases; C018728:N-acetylneuraminate lyase; C013959:dimethylacetamide; C008261:lead acetate; D002246:Carbon Disulfide
vernacular_title: Obmen sialosoderzhashchikh glikoproteidov i aktivnost' fermentov lizosom pri neĭrotropnom éffekte nekotorykh khimicheskikh faktorov okruzhaiushcheĭ sredy.