Double-blind capillaroscopic study of the activity of buflomedil in Raynaud's syndrome: a report on 80 cases.
A double-blind study was performed to compare the effects of buflomedil versus placebo on the capillaroscopic images of the nailbed before and after a cold test in 80 patients with Raynaud phenomenon. The results were scored according to the elements of capillaroscopy (number of capillaries, size, density). Buflomedil was found to significantly better than a placebo (p less than 0.02).
D002196:Capillaries / Q000000981:diagnostic imaging / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008853:Microscopy; D009262:Nails / Q000098:blood supply*; D011759:Pyrrolidines; D011859:Radiography; D011928:Raynaud Disease / Q000175:diagnosis; D013577:Syndrome; D014665:Vasodilator Agents
D011759:Pyrrolidines; D014665:Vasodilator Agents; C010651:buflomedil