title: In vivo pheromone activity in Nippostrongylus brasiliensis (nematoda).
abstract: Both sexes of Nippostrongylus brasiliensis were distributed in the anterior 50% of the mouse intestine from 4.5 to 8 days postinfection. Most worms were recovered from a region that represented 20% of the pyloric-caecal distance. The worms' dispersal increased to 70 to 75% of the intestine at 10 days postinfection. Food deprivation for 48 hr had a similar effect. Surgical transfer of females to the anterior region of the intestine induced dosage-dependent locomotion by posteriorly placed males. The males' response was reduced or eliminated by lengthy distances from females, peristalsis and pre-exposure to female pheromone. Females were attractive from 4 to 10 days postinfection, based on the male's in vivo response. Males were responsive to pheromone at 6 to 10 days postinfection.
mesh_terms: D000818:Animals; D001681:Biological Assay; D004435:Eating; D005260:Female; D007422:Intestines / Q000469:parasitology*; D008297:Male; D051379:Mice; D009068:Movement; D009349:Nematode Infections / Q000469:parasitology*; D009559:Nippostrongylus / Q000502:physiology*; D010675:Pheromones / Q000502:physiology*; D012724:Sex Attractants / Q000502:physiology*; D013217:Starvation; D013997:Time Factors
chemical_list: D010675:Pheromones; D012724:Sex Attractants