title: [Analysis of structural divergence of H1N1 serotype influenza virus individual genes].
abstract: A comparative structural analysis of H1N1 influenza virus isolated in 1977 (the A/USSR/90/77 strain) and H1N1 isolates of 1947 (the A/FM/1/47 strain) and 1950 (the A/FW/1/50 strain) have been carried out by oligonucleotide mapping of individual viral RNA segments. Seven of eight genes of A/USSR/90/77 strain have a high degree of homology with corresponding genes of A/FW/1/50 strain, especially the genes coding the NP and P2 proteins. At the same time the gene coding matrix (M) protein has higher structural similarity to the corresponding gene of A/FM/1/47 strain. Based on the results presented one may conclude that the A/USSR/90/77 epidemic strain is a recombinant virus.
mesh_terms: D004279:DNA, Viral; D005814:Genes, Viral; D053118:Influenza A Virus, H1N1 Subtype; D009980:Influenza A virus / Q000235:genetics*; D009838:Oligodeoxyribonucleotides / Q000032:analysis; D013045:Species Specificity; D014764:Viral Proteins / Q000235:genetics
chemical_list: D004279:DNA, Viral; D009838:Oligodeoxyribonucleotides; D014764:Viral Proteins
vernacular_title: Analiz strukturnoĭ izmenchivosti individual'nykh genov épidemicheskikh shtammov virusa grippa serotipa H1N1.