[The reproducibility of the bronchospasmolytic effects of isoprenaline tests repeated after long intervals under ambulatory conditions].
The functional results of 3 bronchospasmolytic tests using 4 puffs of an isoprenaline-spray repeated in large intervals were compared on 104 patients suffering from obstructive lung diseases. The correlation coefficients and the coefficients of determination of the differences of the forced expiration volume in one second before and after the tests showed no good correspondence of the spasmolytic effects. It is to be stated that the dimensions of an improvement of the functional results can not be prognosticated, not even on condition that the functional situation before the test, the inhalant and the dose would be the same on the repeated test. Therefore an actual test using a known effective drug for the control has to be demanded for the investigation of on bronchospasmolytic inhalant.
D005541:Forced Expiratory Volume; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D008173:Lung Diseases, Obstructive / Q000175:diagnosis*; D008875:Middle Aged; D013997:Time Factors
D007545:Isoproterenol
Zur Reproduzierbarkeit von Bronchospasmolysetesten über lngere Zeiträume unter ambulanten Bedingungen.