title: To the management of the solitary thyroid nodule.
abstract: Excisional biopsy with peroperative frozen section and later paraffin section examination was performed in 107 consecutive cases of solitary thyroid nodules. Frozen section gave a correct diagnosis in 99 cases (92%). A false benign diagnosis was made in 6 cases, one was inconclusive and one was false malignant (Hürthle cell tumor). Technetium scintigraphy was of no definite diagnostic value. Malignancy was found in 25 cases (23%) in which the whole gland was removed. Multicentric bilateral lobe involvement was encountered in 7 patients. Lack of reliable preoperative diagnostic methods makes liberal excisional biopsy of all solitary thyroid nodules advisable.
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000236:Adenoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy