title: Work of breathing, intra-thoracic pressure and clinical findings in a group of babies with bronchiolitis.
abstract: Total work of breathing was measured on 55 occasions on 26 babies with acute bronchiolitis using a respiratory jacket to measure tidal volume and a naso-gastric tube to record oesophageal pressure. Work of breathing was increased six-fold on average and on one occasion exceeded forty times the expected. Approximately 40% of the intra-thoracic pressure swing was positive relative to atmospheric. It was not possible to correlate the work of breathing measurements with detailed clinical assessments.
mesh_terms: D000208:Acute Disease; D001990:Bronchiolitis, Viral / Q000503:physiopathology*; D004947:Esophagus / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011312:Pressure; D013990:Tidal Volume; D014939:Work of Breathing