Hemoperfusion in quinidine intoxication.
A case report on quinidine intoxication is presented. After having ingested 8.1 g quinidine the patient had clinical and ECG signs of a severe intoxication and a serum quinidine level of 8.5 mg 1. She was treated for six hours with charcoal hemoperfusion. Serum quinidine was on an average 36% lower after than before the cartridge. The mean quinidine clearance of hemoperfusion was 24 ml/min. All clinical and ECG signs of quinidine intoxication were normalized during hemoperfusion. The data justify that hemoperfusion is probably the best way to treat severe quinidine intoxication.
D000328:Adult; D002606:Charcoal / Q000627:therapeutic use; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D011802:Quinidine / Q000506:poisoning*; D013406:Suicide, Attempted
D002606:Charcoal; D011802:Quinidine