Vascular stability and middle molecules removal in hypertonic haemodiafiltration.
Hypertonic haemodiafiltration is a simultaneous hypertonic (delta 550, Na 275mEq/L) low volume (7.2 litres) haemofiltration and hypotonic (delta 282) short time (180') haemodialysis. Reduction of the predialysis body pool of MM (-48 per cent) and small molecules (-33 per cent) was obtained. No relationship between vascular stability and MM removal was observed. However, a net UF of 20.5ml/min and a greater removal of solutes up to 1500 daltons mw were obtained with a three hours thrice weekly dialysis programme.
D001002:Anuria / Q000097:blood / Q000628:therapy; D001769:Blood; D006801:Humans; D006982:Hypertonic Solutions; D008970:Molecular Weight; D009994:Osmolar Concentration; D006435:Renal Dialysis; D012964:Sodium / Q000097:blood; D014118:Toxins, Biological; D014462:Ultrafiltration / Q000379:methods*; D014508:Urea
D006982:Hypertonic Solutions; D014118:Toxins, Biological; C026865:uremia middle molecule toxins; D014508:Urea; D012964:Sodium