title: Anaerobic plate method for assaying antimicrobial agents in serum.
abstract: An anaerobic agar plate method was devised for the assay of antimicrobial agents in serum by using a strain of Clostridium bifermentans. The method gave reproducible and accurate in assays of chloramphenicol, clindamycin, and metronidazole alone or in the presence of beta-lactam or aminoglycoside antibiotics.
mesh_terms: D000693:Anaerobiosis; D000900:Anti-Bacterial Agents / Q000097:blood* / Q000494:pharmacology; D001681:Biological Assay / Q000379:methods; D003013:Clostridium / Q000187:drug effects; D006801:Humans; D008795:Metronidazole / Q000097:blood
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole