[Identification of drugs in toxic doses in biological fluids using infrared Spectrophotometry].
A method permitting rapid analysis of biological samples from patients suspected of being intoxicated is reported. The method is based on: a) extraction of the active principles of biological samples with chloroform; b) drying and preparation of a disc of KBr; c) spectrophotometric analysis; d) integration of data from laboratory analyses with the clinical data from the patient. A number of clinical cases are also reported in which adoption of the method permitted rapid diagnosis of the possible aetiology of the toxic pictures observed.
D001826:Body Fluids / Q000032:analysis*; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis*; D011041:Poisoning / Q000378:metabolism*; D013055:Spectrophotometry, Infrared / Q000379:methods
D004364:Pharmaceutical Preparations
Riconoscimento di farmaci in dose tossica nei liquidi biologici mediante spettrofotometria I.R.