Roentgencephalometric analysis of craniofacial growth in the Johanson-Blizzard syndrome.
Two male patients with Johanson-Blizzard syndrome are presented. Radiocephalometry of the craniofacial complex disclosed findings previously unreported. The radiographic observations, extending from age 6 months to 5 years of age in one case, revealed a decelerating growth pattern with minimal effect on the neurocranium, but with greater effect on facial growth. Maxillary growth was more severely retarded than mandibular growth. The phenotypic characteristics related to growth retardation are age dependent in the severity of their expression.
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000473:pathology; D000367:Age Factors; D002508:Cephalometry; D002648:Child; D002675:Child, Preschool; D005147:Facial Bones / Q000254:growth & development; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D012886:Skull / Q000254:growth & development