[The effect of neostigmine and atropine on gastro-oesophageal reflux (author's transl)].
During 6 hours continuous pH-measurements were undertaken to study the effect of neostigmine (0,5 mg s.c.) and atropine (0,5 mg s.c.) on gastro-oesophageal reflex after a standardised meal (n=18). Mean total reflux duration, single reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were not effected by neostigmine. Mean total reflux duration and mean reflux frequency were reduced by atropine during the first hour p.i. (a less than 0,01).
D001285:Atropine / Q000627:therapeutic use*; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009388:Neostigmine / Q000627:therapeutic use*; D013270:Stomach / Q000032:analysis
D009388:Neostigmine; D001285:Atropine
Der Effekt von Neostigmin und Atropin auf den gastroösophagealen Reflux.