title: Alterations in local cerebral glucose utilisation in specific thalamic nuclei following apomorphine.
abstract: The alterations in local cerebral glucose utilisation in eight discrete nuclei in the thalamus following the administration of apomorphine (0.5 mg kg-1) have been investigated with the autoradiographic 2-deoxyglucose technique in 11 conscious rats. In two thalamic nuclei (parafascicular and ventrolateral nuclei), glucose utilisation was significantly elevated following apomorphine; in two thalamic nuclei (the anterior medial and anterior ventral nuclei), glucose utilisation was significantly reduced following apomorphine; and in four nuclei (lateral geniculate, medial geniculate, mediodorsal, and lateral thalamic nuclei), glucose use was unchanged.
mesh_terms: D000818:Animals; D001058:Apomorphine / Q000494:pharmacology*; D001345:Autoradiography; D001786:Blood Glucose; D001921:Brain / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013787:Thalamic Nuclei / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D005947:Glucose; D001058:Apomorphine