Hyperlipemia among 1407 Danish children whose fathers have died from ischemic heart disease before age 45.
1407 children whose fathers had died from ischemic heart disease before age 45 were investigated. 15% had hypercholesterolemia and 8% hypertriglyceridemia at visit 1. At visit 2 and 3 this number of children with hyperlipemia fell to a minimum of 3% and 1.4%, resp. which is around 10 times higher than in a reference population. 1.8% of the children had familial hypercholesterolemia (FH) which is 10-15 times higher than in a reference population. These findings indicate that serum lipids should always be measured in children from such coronary heart risk families, and a decision made whether or not their permanent hyperlipemia should be treated.
D000293:Adolescent; D000328:Adult; D003327:Coronary Disease / Q000401:mortality* / Q000517:prevention & control; D003718:Denmark; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology* / Q000209:etiology; D006938:Hyperlipoproteinemia Type II / Q000453:epidemiology; D006953:Hyperlipoproteinemia Type IV / Q000453:epidemiology; D006951:Hyperlipoproteinemias / Q000453:epidemiology* / Q000209:etiology; D008055:Lipids / Q000097:blood; D008297:Male; D010375:Pedigree; D012306:Risk
D008055:Lipids