title: Effect of 1,3-butylene glycol on growth and in vivo and in vitro lipogenesis by turkey poults.
abstract: A series of feeding trials lasting 21 days was conducted with Large White turkey poults to determine the effects of 0, 12.5, and 25% energy as 1,3-butylene glycol (BG) on growth and on both in vivo and in vitro lipogenesis. The substitution of 12.5 and 25% of the energy as BG and on both in vivo and in vitro lipogenesis. The substitution of 12.5 and 25% of the energy as BG depressed growth and feed efficiency of 21-day-old poults (P less than 01). The relative liver size was increased by BG (P less than .01) while liver lipid per 100 g of body weight was decreased (P less than .01) by BG. IN vivo lipogenesis, determined by the incorporation of tritiated water into liver fatty acids was decreased (P less than .05) by BG. The evolvement of CO2 from both (1-14C) acetate and from (U-14C) glucose was decreased by BG. The results of this study indicate that while lipogenesis can be decreased by BG, growth is also decreased. Therefore, the regulation of growth parallels the regulation of lipid synthesis in the turkey poult.
mesh_terms: D000818:Animals; D002072:Butylene Glycols / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism; D006128:Growth / Q000187:drug effects*; D066298:In Vitro Techniques; D008055:Lipids / Q000096:biosynthesis*; D010084:Oxidation-Reduction; D011200:Poultry / Q000378:metabolism; D014422:Turkeys / Q000254:growth & development / Q000378:metabolism*
chemical_list: D002072:Butylene Glycols; D008055:Lipids; D005947:Glucose