[Variations of serum BuChe activity during C M F therapy].
As the Authors and Others have already demonstrated, cyclophosphamide leads to a rapid and prolonged decrease in the serum cholinesterase activity. In this work, the behaviour of the serum cholinesterase in patients subjected to C M F polychemotherapy (CTX, VCR, FU) has been studied. The grouping of patients on the basis of serum cholinesterase values before treatment has demonstrated that the enzymatic activity decrease arrives at level practically homogeneous. A month after interruption of therapy values equal to those at starting point have been observed.
D001943:Breast Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D002091:Butyrylcholinesterase / Q000097:blood*; D002802:Cholinesterases / Q000097:blood*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000201:enzymology
D003520:Cyclophosphamide; D002091:Butyrylcholinesterase; D002802:Cholinesterases; D005472:Fluorouracil; D008727:Methotrexate
Variazione dell'attività della BuChe sierica in corso di trattamento C M F.