[Hepatic calcifications in isolated necrotizing, granulomatous hepatitis due to Brucella. A case report and review of the literature (author's transl)].
A case of isolated necrotizing, granulomatous hepatitis of Brucella origin is discussed, together with 6 similar cases reported in the published literature. The clinical picture is dominated by the history of the patient (occupation, geographical location), fever, right hypochondrial pain, and altered general condition. Radiological examination shows characteristic calcifications. Diagnosis is confirmed by serology, Brucella suis usually being involved. Pathological appearances are typical : large foci of hepatic necrosis surrounded by marked inflammatory zones with histiocytic cells arranged in palisades. The only possible treatment is surgical.
D002006:Brucellosis / Q000175:diagnosis*; D002114:Calcinosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006099:Granuloma / Q000209:etiology; D006505:Hepatitis / Q000150:complications* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008107:Liver Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000209:etiology
Calcifications hépatiques au cours des hépatites brucellinnes granulomateuses et nécrosantes isolées. A propos d'un cas et revue de la littérature.