Synthetic studies on enkephalin analogs. II. Enhanced analgesic activity of H-Tyr-D-Ala-Gly-Phe-NHNH-CO-CH2CH3 following N-methylation of Tyr and Phe.
D000700:Analgesics / Q000138:chemical synthesis*; D000818:Animals; D004723:Endorphins / Q000138:chemical synthesis*; D004745:Enkephalins / Q000138:chemical synthesis* / Q000494:pharmacology; D006834:Hydrazines / Q000138:chemical synthesis / Q000494:pharmacology; D008297:Male; D051379:Mice; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000700:Analgesics; D004723:Endorphins; D004745:Enkephalins; D006834:Hydrazines; D009842:Oligopeptides