Effects of naftidrofuryl on local cerebral glucose utilization in the rat.
The effects of naftidrofuryl on local cerebral glucose utilization have been examined in 21 lightly restrained, conscious rats by means of the quantitative autoradiographic 2-deoxyglucose technique. Naftidrofuryl (15, 30, and 45 mg/kg, i.p.) did not significantly alter the rate of glucose utilization in any of the 29 gray matter or 4 white matter areas that were examined.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D004734:Energy Metabolism / Q000187:drug effects; D005663:Furans / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism*; D008297:Male; D009257:Nafronyl / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D014665:Vasodilator Agents / Q000494:pharmacology*
D005663:Furans; D014665:Vasodilator Agents; D009257:Nafronyl; D005947:Glucose