A study of renal-efferent neurones and their neural connexions within cat renal ganglia using intracellular electrodes.
1. Intracellular recordings were made, in vitro, fron neurones located within left renal ganglia and left coeliac ganglia of cat solar plexus. 2. Forty-three percent of the neurones of the renal ganglia tested were identified by antidromic activation as renal-efferent neurones. 3. Electrical stimulation of all nerve trunks emanating from renal ganglia, other than the renal nerves, did not antidromically activate renal ganglia neurones. Neurones not antidromically activated were designated as non-efferent neurones. 4. Neurones within the renal ganglia were also characterized as phasic or tonic neurones depending on their pattern of discharge. 5. Electrical stimulation of renal nerves produced excitatory synaptic potentials (e.p.s.p.s) in 18% of the renal-efferent neurones. 6. Compounded e.p.s.p.s were produced in 50% of the renal ganglia neurones tested by stimulation of the ipsilateral splanchnic nerves and in 84% of the neurones upon stimulation of the vertebral nerve. 7. Synaptic responses demonstrating characteristics typical of those induced by activation of multisynaptic neural pathways were produced upon stimulation of renal and coeliac nerves. 8. The results of this study indicate that the electrophysiological properties of renal-efferent neurones vary considerably from neurone to neurone and that these neurones receive synaptic inputs from a variety of preganglionic fibres and possibly from other neurones having their soma located within the solar plexus.
D000818:Animals; D002415:Cats; D002447:Celiac Plexus / Q000502:physiology*; D004525:Efferent Pathways / Q000502:physiology; D004553:Electric Conductivity; D004566:Electrodes; D005728:Ganglia, Sympathetic / Q000502:physiology*; D066298:In Vitro Techniques; D007668:Kidney / Q000294:innervation*; D008564:Membrane Potentials; D009476:Neurons, Efferent / Q000502:physiology*; D013569:Synapses / Q000502:physiology