Jejunal absorption rates of glucose and glycine in post-infective tropical malabsorption.
In a prospective study jejunal absorption rates of glucose (from a 200 mmol 1-1 solution) and glycine (from a 100 mmol 1-1 solution) were measured, using a perfusion technique, in nine patients with clinical evidence of post-infective tropical malabsorption (TM group) and in 10 others with trivial symptoms who had also visited the tropics (control group); all were of northern European origin. Seven and one in the two groups, respectively, had Giardia lamblia infections. Mean glucose absorption rate was significantly impaired by TM (P less than 0.01); mean rate for glycine was also depressed but not significantly. Presence of G. lamblia did not affect the severity of malabsorption although numbers studied were small.
D000328:Adult; D005873:Giardiasis / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D007583:Jejunum / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013182:Sprue, Tropical / Q000378:metabolism*; D014867:Water / Q000378:metabolism
D014867:Water; D005947:Glucose; D005998:Glycine