title: Electron microscopic study of carcinoma of the colon.
abstract: During electron microscopic studies of 24 carcinomas of the colon the authors compared the ultrastructural characteristics of tumorous epithelial cells of various degrees of differentiation. Beside the epithelial elements, the myofibroblast reaction, considered to be a local immune reaction due to invasive tumour cells, observable in the stroma of tumours was also treated in detail. It was observed that myofibroblasts develop from the fibroblasts of the matrix of colonic mucosa.
mesh_terms: D000230:Adenocarcinoma / Q000648:ultrastructure*; D002277:Carcinoma / Q000648:ultrastructure*; D002454:Cell Differentiation; D003106:Colon / Q000648:ultrastructure; D003110:Colonic Neoplasms / Q000145:classification / Q000648:ultrastructure*; D006801:Humans; D007413:Intestinal Mucosa / Q000648:ultrastructure; D008854:Microscopy, Electron; D009361:Neoplasm Invasiveness; D009940:Organoids / Q000648:ultrastructure