[Effect of ethanol on the genetic apparatus of mammalian germ cells].
A study was made of the frequency of dominant lethal mutations in germ cells at different stages of spermatogenesis, the level of chromosome aberrations in embryonic cells of male progeny treated with ethanol as well as the influence of ethanol on chromosomal apparatus of germ cells. Ethanol possesses a mutagenic activity, induces dominant lethal mutations which are more pronounced when gametes were treated 2 weeks before fertilization.
D000818:Animals; D002869:Chromosome Aberrations; D020964:Embryo Loss / Q000139:chemically induced; D004622:Embryo, Mammalian / Q000187:drug effects; D047108:Embryonic Development / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation; D011247:Pregnancy; D051381:Rats; D013094:Spermatozoa / Q000187:drug effects*
D000431:Ethanol
Vliianie étanola na geneticheskiĭ apparat polovykh kletok mlekopitaiushchikh.