title: Gentamicin tissue concentration in various avian species following recommended dosage therapy.
abstract: Plasma and tissue drug concentrations were compared in eastern bobwhite quail (Colinus virginianus virginianus) and pigeons (Columba livia) given gentamicin by IM administration at the dosage of 10 mg/kg, and in greater sandhill cranes (Grus canadensis tabida) and hybrid rosybill ducks (Netta sp) given the same antibiotic at a dosage of 5 mg/kg. Quail and cranes had significantly higher liver concentrations of gentamicin at 6 hours after injection than did pigeons and ducks. Cranes had significantly higher plasma concentrations than did ducks at 6 hours after injection. Compared with plasma values, gentamicin concentrations were significantly higher in the liver of cranes at 12 hours after injection, and in the kidneys at 18 hours.
mesh_terms: D000818:Animals; D001717:Birds / Q000378:metabolism*; D005839:Gentamicins / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D007273:Injections, Intramuscular / Q000662:veterinary; D013045:Species Specificity; D014018:Tissue Distribution
chemical_list: D005839:Gentamicins