title: [Purine base metabolism in the mother-placenta-fetus system in experimental hypoxia].
abstract: In acute deficiency of oxygen inhibition of purine bases turnover as well as degradation of their high molecular precursors occurred in the system mother-placenta-fetus. Acute hypoxia was accompanied by distinct increase in content of adenine, xanthine + + guanine and uric acid in blood of pregnant rats, in placenta and blood of newborn animals. Long-term effect of hypoxia resulted in adaptation of purine metabolism. In this case production of adenosine and adenosine monophosphate was activated.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005311:Fetal Hypoxia / Q000378:metabolism*; D000860:Hypoxia / Q000378:metabolism*; D010313:Partial Pressure; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011687:Purines / Q000378:metabolism*; D051381:Rats
chemical_list: D011687:Purines
vernacular_title: Obmen purinovykh osnovaniĭ v sisteme mat'-platsenta-plod pri éksperimental'noĭ gipoksii.