Antibody kinetics in response to vaccination against Babesia bovis.
The kinetics of specific indirect fluorescent antibody (IFA) test titers and total serum immunoglobulin (Ig) G and IgM values were determined in cattle vaccinated with culture-derived soluble Babesia organisms. Nineteen days after challenge exposure (postinoculation day 67), vaccinated cattle had a strong anamnestic response and mean IFA titers reached 1:48,710. Serum IgG and IgM concentrations were increased after vaccination and after challenge exposure. A nonspecific suppression of total IgG (controls) and IgM (vaccinated animals and controls) values also was observed, the depression coinciding with the period of peak parasitemia.
D000818:Animals; D000917:Antibody Formation; D001403:Babesia / Q000276:immunology*; D001404:Babesiosis / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007700:Kinetics; D014611:Vaccination / Q000662:veterinary
D007074:Immunoglobulin G; D007075:Immunoglobulin M