title: Lower gastrointestinal side effects of nonsteroidal antiinflammatory drugs.
abstract: It has been well accepted that the nonsteroidal antiinflammatory drugs (NSAID) can cause upper gastrointestinal (GI) blood loss and reactivation of peptic ulcer disease. This report describes 3 patients in whom the ingestion of a NSAID was temporally associated with serious lower GI disease, including bleeding in 2 patients. These cases suggest an association between NSAID and activation of serious lower GI disease.
mesh_terms: D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000893:Anti-Inflammatory Agents