title: Reproductive performance of gilts exposed to porcine parvovirus at 56 or 70 days of gestation.
abstract: A total of 18 pregnant gilts, which were free of antibody for porcine parvovirus (PPV), were exposed oronasally to PPV on either the 56th day (9 gilts) or 70th day (9 gilts) of the gestation to determine whether infection at these times would affect their reproductive performance. The gilts were either necropsied late in gestation or allowed to farrow, and their fetuses and pigs were tested for evidence of infection. Gilts remained clinically healthy throughout the experiment, and none farrowed prematurely. litters of 7 of 9 gilts exposed to PPV at 56 days of the gestation were infected transplacentally, and PPV caused death of fetuses in 5 of the infected litters. These litters comprised 29 dead fetuses (2 to 12/litter) and 31 live fetuses or pigs (1 to 10/litter). In addition, PPV may have been directly or indirectly responsible for an increased frequency of stillbirth and neonatal death, but the role of PPV in these conditions was difficult to assess. Litters of 6 to 9 gilts exposed to PPV at 70 days of the gestation also were infected transplacentally, but in contrast to earlier infection, PPV did not cause fetal death in these litters.
mesh_terms: D000818:Animals; D005260:Female; D005313:Fetal Death / Q000209:etiology / Q000662:veterinary; D010321:Parvoviridae; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000503:physiopathology / Q000635:transmission / Q000662:veterinary*; D012098:Reproduction; D013552:Swine; D013553:Swine Diseases / Q000503:physiopathology* / Q000635:transmission; D014777:Virus Diseases / Q000503:physiopathology / Q000635:transmission / Q000662:veterinary*