Effect of chlorpromazine on the ultrastructure of Staphylococcus aureus.
The ultrastructure of Staphylococcus aureus grown on plates containing chlorpromazine (CPZ) in concentrations up to a bacteriostatic level (50 micrograms/ml) was studied. High concentrations of CPZ induced large mesosome-like structures and asymmetrical cell divisions in a considerable number of cells.
D002455:Cell Division / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects; D002473:Cell Wall / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008854:Microscopy, Electron; D013211:Staphylococcus aureus / Q000187:drug effects / Q000648:ultrastructure*
D002746:Chlorpromazine