Estimation of recuperation of renal function in obstructive uropathy: an experimental study in rats with the use of renoscan.
In order to obtain an evaluation of the renal function after removal of a cause of obstructive uropathy, the renal scan was experimented in rats. The methods used consisted of the obstruction of the right ureter and of Hippuran131 scanning which was performed weekly. The patency of the ureter was re-established at different times and, in some cases, the left ureter was obstructed during this second operation. Delay and reduction in Hippuran131 uptake was directly related to the duration of the obstruction and recuperation of function was inversely related to the same parameter. The contralateral ureter obstruction caused a significant improvement in right renal function. Recuperation was also observed in rats reoperated on after seven or eight weeks.
D000818:Animals; D004195:Disease Models, Animal; D007465:Iodohippuric Acid; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D011379:Prognosis; D011877:Radionuclide Imaging; D051381:Rats; D013997:Time Factors; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000503:physiopathology*
D007465:Iodohippuric Acid