title: The hydrophobicities of cholera toxin, tetanus toxin and their components.
abstract: 1. Charge-shift electrophoresis showed that cholera toxin and its subunits have no hydrophobic surfaces. 2. Amino-acid composition and sequence data suggested that the proteins have no masked hydrophobic regions. 3. The A subunit of cholera toxin may interact with polar molecules in the membrane to exert its effect inside the cell. 4. The only hydrophobic part of tetanus toxin was the H-chain.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D002772:Cholera Toxin / Q000378:metabolism*; D004587:Electrophoresis, Agar Gel; D011506:Proteins / Q000378:metabolism; D013744:Tetanus Toxin / Q000378:metabolism*; D014867:Water / Q000378:metabolism
chemical_list: D000596:Amino Acids; D011506:Proteins; D013744:Tetanus Toxin; D014867:Water; D002772:Cholera Toxin