title: Clinicopathologic correlations in pseudocapsule formation after breast augmentation.
abstract: In 2,000 patients who underwent augmentation mammoplasties with different types of prostheses, the thickness of the pseudocapsules around gel-filled implants was greater than that of the pseudocapsules forming around inflatable implants. This observation was corroborated by an independent histologic study. Deposition of liquid silicone into the pseudo-capsules as well as the adjacent breast tissue and migration into capillaries was demonstrated. Until an impermeable shell or a non-transgressive gel can be manufactured, gel-filled implants should not be used.
mesh_terms: D001940:Breast / Q000473:pathology / Q000601:surgery*; D005260:Female; D005547:Foreign Bodies; D005782:Gels; D006801:Humans; D011183:Postoperative Complications; D019736:Prostheses and Implants / Q000009:adverse effects*; D012828:Silicones; D013518:Surgery, Plastic
chemical_list: D005782:Gels; D012828:Silicones