title: Plasma dopamine-beta-hydroxylase and platelet monoamine oxidase activities in pigs with different susceptibility to the malignant hyperthermia syndrome by halothane.
abstract: Plasma DBH and platelet MAO activities were measured by radioenzymatic assay in 10 Large-White and 20 Piétrain pigs 9 to 11 weeks old. Piétrain pigs within the same litter, challenged by halothane, were classified as malignant hyperthermia (MH) susceptible or not according to their reaction. The Large-White pig strain was not susceptible to MH. Plasma DBH activity did not differ according to strain or to MH susceptibility. Platelet MAO was lower in Large-White pigs but was not affected by MH susceptibility in Piétrain pigs. The results do not confirm any nervous differences in MH-susceptible pigs.
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000201:enzymology*; D004198:Disease Susceptibility; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D008297:Male; D008305:Malignant Hyperthermia / Q000201:enzymology / Q000662:veterinary*; D008995:Monoamine Oxidase / Q000097:blood*; D013552:Swine; D013553:Swine Diseases / Q000139:chemically induced / Q000201:enzymology*
chemical_list: D004299:Dopamine beta-Hydroxylase; D008995:Monoamine Oxidase; D006221:Halothane