[The biological basis of therapeutic strategies in malignant gliomas. General oncological data, current methods and results, prospects (author's transl)].
The authors summarize briefly the biological basis of therapeutic regiments against malignant gliomas. They outline some factors able to contribute to the poor results that are obtained with the now in use strategies: paucity of drugs, tumoral sites out of drug access, inadequate timing of prescriptions, variable and unpredictable drug sensitivity of cells in one given tumor. They encompass the eventuality of progress upon the use of new laboratory methods allowing a better under standing of tumor biology.
D001932:Brain Neoplasms / Q000188:drug therapy / Q000473:pathology*; D002453:Cell Cycle; D005910:Glioma / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D006801:Humans
Bases biologiques des stratégies thérapeutiques des gliomes malins. Données oncologiques générales, place des moyens actuels et résultats, perspectives.