title: Intracranial pressure monitoring in severe pediatric near-drowning.
abstract: Between April 1979 and April 1981, 20 near-drowned children admitted to Childrens Hospital of Los Angeles with a Glasgow coma score of 3 underwent intracranial pressure (ICP) monitoring and brain resuscitative therapy. By the 3rd hospital day, 14 patients had developed ICP elevation above 20 torr, and 11 of these had sustained intracranial hypertension above 30 torr. Ten of these children died, and 4 remain in a persistent vegetative state. Of 6 patients whose ICP never exceeded 20 torr, 3 recovered completely, 1 died, and 2 remain without any cognitive function. The salvage rate for patients with normal ICP after near-drowning accidents is significantly better than that for patients in whom the ICP is elevated (P = 0.017). Intracranial hypertension is associated with a uniformly bad outcome and is frequent in patients who die or suffer permanent, severe central nervous system damage after near-drowning.
mesh_terms: D002648:Child; D003128:Coma / Q000175:diagnosis* / Q000209:etiology; D004332:Drowning; D006801:Humans; D007427:Intracranial Pressure; D008991:Monitoring, Physiologic; D010424:Pentobarbital / Q000627:therapeutic use; D011379:Prognosis; D012151:Resuscitation
chemical_list: D010424:Pentobarbital