Estimation of the amount of drug absorbed in acetaminophen poisoning: a case report.
A case of acute acetaminophen overdose has been presented in which good agreement between the observed and the calculated urinary excretion of acetaminophen was obtained using the pharmacokinetic model of Prescott et al (1). This case exemplifies the application of pharmacokinetic principles in the determination of the actual amount of drug absorbed in instances of drug overdose.
D000042:Absorption; D000082:Acetaminophen / Q000378:metabolism / Q000506:poisoning*; D000328:Adult; D006801:Humans; D007700:Kinetics; D008297:Male
D000082:Acetaminophen