Mild elevations of plasma ornithine in homocystinuria.
Hyperornithinemia was found on many occasions during monitoring of amino acids in the fasting plasma of homocystinuric patients. Ornithine concentrations were elevated 2- to 3-fold above the normal mean value. Hyperornithinemia was of much less marked degree than that seen in gyrate atrophy of the choroid and retina, and was not accompanied by overflow ornithinuria or hypolysinemia. Elevations in plasma ornithine concentrations in homocystinuric patients were generally proportional to elevations in the plasma concentration of homocystine, but not that of methionine.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006712:Homocystinuria / Q000097:blood*; D006801:Humans; D008297:Male; D008715:Methionine / Q000097:blood; D009952:Ornithine / Q000097:blood*; D011736:Pyridoxine / Q000494:pharmacology
D008715:Methionine; D009952:Ornithine; D011736:Pyridoxine