Failure of in vitro induction of killer cells in C57BL/6 anti-C57BL/6-LYT1.1 strain combination.
Several in vivo preimmunization schedules which are commonly used for induction of in vitro cell-mediated cytotoxicity against weak transplantation antigens have been tested for ability to generate killer cells in congenic anti B6-Lyt1.1 strain combination. Under the conditions studied no cytotoxic cells were generated. Under the same same conditions good cytotoxic response against H-Y antigen was observed.
D000818:Animals; D000950:Antigens, Ly / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D005260:Female; D006182:H-Y Antigen / Q000276:immunology; D007114:Immunization; D007115:Immunization Schedule; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL
D000950:Antigens, Ly; D006182:H-Y Antigen