An in vivo model for evaluating the response of pulp to various biomaterials.
An in vivo model has been designed to study the acute response of exposed or unexposed dental pulp to the topical application of various biomaterials. This model permits sequential microscopic observations of the microvascular system of dental pulp before and after application of pulp capping agents, cementing agents, or cavity liners. The use of this experimental model provides useful information related to the tolerability of dental pulp to various biomaterials used in dentistry. Furthermore, this model serves as a useful supplement to more traditional long term methods for evaluating the biocompatability of dental materials.
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D003782:Dental Pulp / Q000098:blood supply / Q000187:drug effects*; D005260:Female; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains
D001672:Biocompatible Materials