[Detoxication by hemoperfusion].
In 13 patients (2 males, 11 females, 15-70 years of age) on account of severe intoxications with hypnotics sedatives, psychopharmaca, in most cases mixed intoxications, with propranolol and halogenized hydrocarbons a 4--8-hour haemoperfusion treatment with amberlite XAD-4-Resin was performed. 11 patients survived, 1 patient died in irreversible cardiogenic shock of a propranolol intoxication, another patient of the sequels of a crotylbarbital and methaqualone intoxication. The curves of the course of the blood concentration of the individual substances showed a good elimination for phenobarbital and crotylbarbital, methaqualone, meprobamat and didropyridine as well as trichlorethylene, a less good elimination for nitrazepam, propranolol and tetrachlorethylene, Altogether the effectiveness of the detoxication clearly higher in the time unit, compared with the dialysis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000506:poisoning; D006993:Hypnotics and Sedatives / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000628:therapy*; D011433:Propranolol / Q000506:poisoning; D011619:Psychotropic Drugs / Q000506:poisoning; D013750:Tetrachloroethylene / Q000506:poisoning
D006846:Hydrocarbons, Halogenated; D006993:Hypnotics and Sedatives; D011619:Psychotropic Drugs; D011433:Propranolol; D013750:Tetrachloroethylene
Detoxikation mittels Hämoperfusion.