An antifolate-induced lesion in newly synthesized DNA.
D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000096:biosynthesis*; D003857:Deoxyuridine / Q000378:metabolism; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D008727:Methotrexate / Q000494:pharmacology; D008970:Molecular Weight; D011739:Pyrimethamine / Q000031:analogs & derivatives* / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism
D005493:Folic Acid Antagonists; C006308:metoprine; D004247:DNA; D013936:Thymidine; D003857:Deoxyuridine; D008727:Methotrexate; D011739:Pyrimethamine