Studies on derivatives of 2-amino-4-p-chlorophenylthiazole-5-acetic acid. IV. Addition reactions of thioglycolic acid to 2-N-aralkylidene derivatives of 2-amino-4-p-chlorophenylthiazole-5-acetic acid.
In the course of studies on compounds with expected antiinflammatory and immunosuppressive activity a series of new derivatives of 2-amino-4-p-chlorophenylthiazole-5-acetic acid have been synthesized. Several new and unexpected details of the chemical properties of these compounds were revealed. The chemical structure of the new compounds was confirmed by degradation and identification of the decomposition products and by spectral analysis.
D000596:Amino Acids; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D007166:Immunosuppressive Agents / Q000138:chemical synthesis; D013844:Thiazoles / Q000138:chemical synthesis*
D000596:Amino Acids; D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D013844:Thiazoles