Studies on the interaction between macrophages and leptospires.
Guinea-pig macrophages exerted no bactericidal activity against either a virulent or a saprophytic strain of leptospira during a 120 min period of contact at 37 degrees C. However, the same macrophages exhibited weak phagocytic powers towards these two strains of leptospira over a similar period of time.
D000818:Animals; D006168:Guinea Pigs; D007919:Leptospira / Q000276:immunology* / Q000648:ultrastructure; D007921:Leptospira interrogans / Q000276:immunology; D008264:Macrophages / Q000276:immunology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D010587:Phagocytosis