title: Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques.
abstract: Least-squares analysis of experimental data from the analytical ultracentrifuge is discussed in detail, with particular attention to the use of interference optics in studying nonideal self-associating macromolecular systems. Several samples are given that describe the application of the technique, the expected precision of the results, and some of its limitations. A FORTRAN IV computer program is available from the authors.
mesh_terms: D003201:Computers; D008970:Molecular Weight; D014461:Ultracentrifugation