title: Lanthanide-induced calcergy.
abstract: The subcutaneous injection of solutions of chloride salts of the rare earths is followed by calcification of the dorsal fascia in the mouse. The concentration of salt required to produce a constant, predictable response varies from salt to salt. The macroscopic outline of the reaction is generally irregular and therefore a quantitative radiological method has been developed to allow an accurate assessment of the dose/response relationship. This with the majority of salts is best described as a log regression and with three as a linear regression.
mesh_terms: D000818:Animals; D002114:Calcinosis / Q000139:chemically induced* / Q000473:pathology; D003240:Connective Tissue Diseases / Q000139:chemically induced* / Q000473:pathology; D004305:Dose-Response Relationship, Drug; D005205:Fascia / Q000473:pathology; D006863:Hydrogen-Ion Concentration; D008297:Male; D008674:Metals, Rare Earth / Q000633:toxicity*; D051379:Mice; D009994:Osmolar Concentration
chemical_list: D008674:Metals, Rare Earth