title: Radioimmunoassay of tobramycin compared to microbial methods.
abstract: A commercial radioimmunoassay (RIA) for tobramycin was compared with microbial methods by determining the concentrations of known standards prepared with pooled human serum. The correlation coefficients were r=0.94 for the RIA method and an agar diffusion procedure using commercial paper disk standard, and r=o.95 for a standard agar well diffusion procedure. The agar well method tended to overestimate the real concentrations.
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D001681:Biological Assay / Q000379:methods; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D011863:Radioimmunoassay / Q000379:methods; D014031:Tobramycin / Q000032:analysis* / Q000097:blood
chemical_list: D000900:Anti-Bacterial Agents; D014031:Tobramycin