[Familial Mediterranean fever, complement, cryofibrinogen, colchicine (author's transl)].
The components C1, C4, C2, C3 of the complement system were measured in a group of 24 patients with Familial mediterranean fever (F.M.F.). The presence of cryofibrinogen and its analysis was performed in the same patient. C4, C2, C3, were increased in the F.M.F. group. Cryofibrinogenemia was found in 42 p. 100 of the patients. The cryofibrinogen was composed of fibrin, fibrinogen and plasma fibronectin. The cryofibrinogen was less frequent in the group of patients treated by colchicine (p less than 0.02).
D000293:Adolescent; D000328:Adult; D003078:Colchicine / Q000627:therapeutic use; D003172:Complement C1 / Q000032:analysis; D003175:Complement C2 / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis*; D003450:Cryoglobulins / Q000032:analysis*; D010505:Familial Mediterranean Fever / Q000097:blood* / Q000188:drug therapy; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D015241:Fibrinogens, Abnormal; D006801:Humans; D008297:Male; D008875:Middle Aged
D003172:Complement C1; D003175:Complement C2; D003176:Complement C3; D003181:Complement C4; D003450:Cryoglobulins; D015241:Fibrinogens, Abnormal; C041874:cryofibrinogen; D005340:Fibrinogen; D003165:Complement System Proteins; D003078:Colchicine
Complément sérique et cryofibrinogène dans la maladie périodique (fièvre méditerranéenne familiale).