title: Arginine vasotocin: effects on open field behavior, whole brain monoamines and plasma corticosterone.
abstract: Two experiments were performed to evaluate the effects of Arginine Vasotocin (AVT) on open field behavior, who brain monoamines and plasma corticosterone. In Experiment 1 rats treated with AVT compared to controls displayed an increased initial latency to move, less postural freezing and increased exploration of the central area of the open field. In Experiment 2 it was found that AVT significantly elevated whole brain 5-HT levels (Experiment 2A) without altering levels of dopamine or norepinephrine. Plasma corticosterone was significantly decreased by AVT treatment (Experiment 2B).
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D003345:Corticosterone / Q000097:blood*; D004298:Dopamine / Q000378:metabolism; D005106:Exploratory Behavior / Q000187:drug effects*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D014668:Vasotocin / Q000494:pharmacology*
chemical_list: D012701:Serotonin; D004298:Dopamine; D014668:Vasotocin; D003345:Corticosterone; D009638:Norepinephrine