Plasma lecithin: cholesterol acyltransferase activity in high- and low-responding rhesus monkeys.
The initial rate of esterification of plasma cholesterol by lecithin: cholesterol acyltransferase (LCAT) was measured in high- and low-responding rhesus monkeys fed a moderately high cholesterol (0.15 mg/kcal) diet. The results show that the rate of esterification of cholesterol in the plasma of the high-responders was significantly (p less than 0.025) higher than that of the low-responding animals. In view of known relationships between LCAT activity and plasma lipoprotein metabolism, it is suggested that the lipoprotein metabolism in the high-responders would differ from that in the low-responders.
D000818:Animals; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000494:pharmacology; D004036:Diet, Atherogenic; D008253:Macaca mulatta; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood*
D002791:Cholesterol, Dietary; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase