title: Initial human trials with an investigational new drug (phase I and 2): planning an management.
mesh_terms: D000328:Adult; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002648:Child; D002986:Clinical Trials as Topic / Q000295:instrumentation / Q000379:methods / Q000592:standards; D003625:Data Collection; D003657:Decision Making; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006805:Human Experimentation; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism; D010600:Pharmacology; D010601:Pharmacology, Clinical; D011340:Problem Solving; D012107:Research Design / Q000592:standards*
chemical_list: D004364:Pharmaceutical Preparations