Goldfish brain extract induces aggregation of acetylcholine receptors on cultured myotubes: increased activity following optic nerve axotomy.
Acetylcholine receptor aggregation-inducing factor(s) is found in goldfish brain extract. The specific activity of the factor(s) is increased during goldfish optic nerve regeneration and peaks at 8 days following the nerve axotomy. It is therefore speculated that this activity is associated with the goldfish visual system plasticity.
D000818:Animals; D001369:Axons / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D002478:Cells, Cultured; D006054:Goldfish; D007700:Kinetics; D009132:Muscles / Q000187:drug effects / Q000502:physiology*; D009900:Optic Nerve / Q000502:physiology*; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000502:physiology*; D014020:Tissue Extracts / Q000494:pharmacology*
D011950:Receptors, Cholinergic; D014020:Tissue Extracts