title: Study of prior biopsies of endometrial cancer patients and controls.
abstract: Prior endometrial biopsies were studied for evaluation of the relationship between hyperplastic endometrial changes and the development of endometrial cancer. Our findings were: A trend for the histologic diagnosis to be more severe in the reexamination. Endometrial hyperplasia preceeded cancer in 20 out of 21 cases. The severe hyperplastic lesions were found 1 to 6 years prior to the diagnosis of endometrial cancer.
mesh_terms: D001706:Biopsy; D004714:Endometrial Hyperplasia / Q000473:pathology; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D014594:Uterine Neoplasms / Q000473:pathology*