Photochemical destruction of the virucidal activities of retinoids and unsaturated fatty acids.
Photochemical damage either to retinoids by near-ultraviolet radiation or to unsaturated fatty acids by near-ultraviolet radiation in the presence of a hydrophobic photosensitizer destroys the virucidal activities of the compounds, as determined by studies on the enveloped bacteriophage ø6.
D000998:Antiviral Agents / Q000528:radiation effects*; D001435:Bacteriophages / Q000187:drug effects; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology / Q000528:radiation effects*; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000494:pharmacology; D010777:Photochemistry; D012172:Retinaldehyde / Q000494:pharmacology; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000528:radiation effects
D000998:Antiviral Agents; D005231:Fatty Acids, Unsaturated; D014801:Vitamin A; D012172:Retinaldehyde; D010100:Oxygen