Effect of testosterone on threshold of pain.
Pain threshold for thermal stimulus was studied in male albino rats before and after three days of treatment with testosterone. It was also determined 15 days after castration and three days after testosterone treatment of castrated rats. There was a significant reduction in pain threshold after testosterone treatment and a marked increase in pain threshold after castration. This increase disappeared after administration of testosterone to the castrated rats.
D000818:Animals; D002369:Castration; D004056:Differential Threshold; D006358:Hot Temperature; D008297:Male; D010146:Pain / Q000188:drug therapy / Q000209:etiology*; D051381:Rats; D013739:Testosterone / Q000502:physiology* / Q000627:therapeutic use
D013739:Testosterone