title: Quantitative eye tracking tests in lead workers.
abstract: A microcomputer system for on-lone analysis of saccadic and smooth-pursuit tracking eye movements is described. Results from a longitudinal study of lead workers and matched controls reveal a consistent decrease in saccade accuracy in the lead workers compared to the controls. Saccade peak velocity and latency and smooth pursuit were not significantly different in the two groups. The abnormal saccade accuracy measurements may indicate a subclinical effect of increased lead absorption, but because of the large scatter in normal values, saccade accuracy measurements are not a reliable indicator of early lead toxicity in a single lead worker.
mesh_terms: D004781:Environmental Exposure; D005133:Eye Movements / Q000187:drug effects*; D006801:Humans; D007854:Lead / Q000494:pharmacology*; D007855:Lead Poisoning / Q000503:physiopathology; D008137:Longitudinal Studies; D008722:Methods; D008838:Microcomputers; D012438:Saccades / Q000187:drug effects
chemical_list: D007854:Lead