[A doubleblind comparison of tramadol and buprenorphine in the control of postoperative pain (author's transl)].
Analgesic effects as well as side effects, circulatory and respiratory parameters of 50 mg tramadol (Tramal) were compared with 0.3 mg buprenorphine (Temgesic) in a doubleblind, randomized study for the relief of postoperative pain. Buprenorphine produced a more potent and longer acting analgesic effect compared to tramadol, although slightly delayed. There were only few and slight side effects and no influence on the circulation and respiration. In the search for a new long-acting and strong analgesic Tramadol proved to be unable to replace buprenorphine in the control of postoperative pain.
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002047:Buprenorphine / Q000009:adverse effects / Q000627:therapeutic use*; D003511:Cyclohexanols / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D008875:Middle Aged; D009019:Morphinans / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D011184:Postoperative Period; D011674:Pulse / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D013997:Time Factors; D014147:Tramadol / Q000009:adverse effects / Q000627:therapeutic use*
D003511:Cyclohexanols; D009019:Morphinans; D014147:Tramadol; D002047:Buprenorphine
Doppelblindvergleichsstudie über die Wirkung von Tramadol und Buprenorphine auf die postoperativen Schmerzen.