[The level of glycohaemoglobin (Hb A1c) in connection with diabetes and pregnancy (author's transl)].
The authors worked out a normal curve using 379 levels obtained over 9 months in 180 normal pregnancies. 6% (with a confidence level between 4.4% and 7.6%) was usual for haemoglobin A1c. Then they compared 42 levels of glycohaemoglobin obtained from 14 pregnant diabetic patients where the mean value was 8.34%. Glycohaemoglobin A1c therefore is a good indicator or the level of stabilisation in diabetic pregnancies in the two months before the estimation is taken. It is therefore possible to think that it does indicate chronic hyperglycaemia and does seem to have a future in screening diabetic pregnancies. On the other hand it does not seem to be of any supplementary value in monitoring the fetus of the diabetic mother in the third trimester of pregnancy because of the small variations in the levels that are obtained as compared with the suddenness of fetal complications.
D001724:Birth Weight; D005260:Female; D006442:Glycated Hemoglobin / Q000097:blood*; D006801:Humans; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood* / Q000503:physiopathology
D006442:Glycated Hemoglobin
Dosage de l'hémoglobine glycosylée (Hb A1c) dans l'association "diabète et grossesse".