An accurate, long-term, pH-sensitive radio pill for ingestion and implantation.
The design of a new radiotelemetry capsule (26 mm long X 7.6 mm diameter), with an in vivo life of 1 month is described in the context of previous work in this field. In vitro evaluation of the capsule indicates an accuracy and performance comparable with a conventional pH meter. Several clinical applications are described, including measurements of gastrointestinal pH in humans and the measurement of extracellular pH in laboratory animals.
D000818:Animals; D000863:Antacids / Q000627:therapeutic use; D002648:Child; D004386:Duodenum; D005110:Extracellular Space; D005744:Gastric Acid / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009374:Neoplasms, Experimental / Q000503:physiopathology; D010182:Pancreatic Diseases / Q000503:physiopathology; D051381:Rats; D013686:Telemetry
D000863:Antacids