Inhibition of lipid peroxidation by the iron-binding protein lactoferrin.
Lactoferrin containing physiological amounts of iron is an inhibitor of lipid peroxidation induced by iron(III) salts and ascorbic acid. It might therefore help to protect neutrophils, inflammatory foci and secretions from metal-ion-dependent oxidative damage.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D002417:Cattle; D005290:Ferric Compounds / Q000494:pharmacology; D006801:Humans; D007781:Lactoferrin / Q000378:metabolism / Q000494:pharmacology*; D007782:Lactoglobulins / Q000494:pharmacology*; D050356:Lipid Metabolism; D008081:Liposomes / Q000378:metabolism; D011485:Protein Binding; D011506:Proteins / Q000494:pharmacology
D005290:Ferric Compounds; D007782:Lactoglobulins; D008081:Liposomes; D011506:Proteins; D007781:Lactoferrin; D001205:Ascorbic Acid