title: Hyperlipemia among 1407 Danish children whose fathers have died from ischemic heart disease before age 45.
abstract: 1407 children whose fathers had died from ischemic heart disease before age 45 were investigated. 15% had hypercholesterolemia and 8% hypertriglyceridemia at visit 1. At visit 2 and 3 this number of children with hyperlipemia fell to a minimum of 3% and 1.4%, resp. which is around 10 times higher than in a reference population. 1.8% of the children had familial hypercholesterolemia (FH) which is 10-15 times higher than in a reference population. These findings indicate that serum lipids should always be measured in children from such coronary heart risk families, and a decision made whether or not their permanent hyperlipemia should be treated.
mesh_terms: D000293:Adolescent; D000328:Adult; D003327:Coronary Disease / Q000401:mortality* / Q000517:prevention & control; D003718:Denmark; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology* / Q000209:etiology; D006938:Hyperlipoproteinemia Type II / Q000453:epidemiology; D006953:Hyperlipoproteinemia Type IV / Q000453:epidemiology; D006951:Hyperlipoproteinemias / Q000453:epidemiology* / Q000209:etiology; D008055:Lipids / Q000097:blood; D008297:Male; D010375:Pedigree; D012306:Risk
chemical_list: D008055:Lipids