Propranolol plasma concentrations and plasmapheresis.
Propranolol plasma concentrations were determined in a patient with hemolytic-uremic syndrome undergoing plasmapheresis before and after the procedure on three occasions. The mean half-life and elimination rate constant during plasmapheresis were estimated to be 25.6 percent of the values obtained without plasmapheresis. These changes suggest that plasmapheresis may influence propranolol disposition.
D000328:Adult; D005260:Female; D006207:Half-Life; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology; D006801:Humans; D010956:Plasmapheresis / Q000009:adverse effects*; D011433:Propranolol / Q000097:blood*
D011433:Propranolol