title: Massive cerebral edema associated with fulminant hepatic failure in acetaminophen overdose: possible role of cranial decompression.
abstract: Cerebral edema may complicate the course of fulminant hepatic failure. Response to conventional therapy has been disappointing. We present a patient with fatal acetaminophen-induced fulminant hepatic failure, with signs and symptoms of cerebral edema, unresponsive to conventional medical therapy. Cranial decompression was carried out. A justification of the need for further evaluation of cranial decompression in such patients is presented.
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D000293:Adolescent; D001929:Brain Edema / Q000209:etiology* / Q000601:surgery; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000150:complications; D011379:Prognosis; D012202:Reye Syndrome / Q000601:surgery
chemical_list: D000082:Acetaminophen