title: [Sites of predilection of leukoplakia and carcinoma of the oral mucosa (author's transl)].
abstract: In a prospective study, begun in 1976, of so far 248 patients with histologically confirmed oral leukoplakia there have been 48 (27 males, 21 females) with precancerous lesions and 25 (22 males, 3 females) with carcinoma. While half of the benign leukoplakias were in the buccal region, precancerous lesions and carcinoma dominated with increasing frequency in the lower half of the oral cavity. Among the precancerous mucosal lesions 23% were in the lateral or ventral region of the tongue, 10% in the sublingual region. Among the carcinomas nearly 10% were at the back of the tongue, 29% in the lateral or ventral region of the tongue, and 23% in the floor of the mouth. Of 22 proven leukoplakias in the sublingual region 20 were either precancerous or carcinoma. In order to improve the early recognition of oral precancerous or cancerous lesions it is essential to include the lower regions in any examination of the oral cavity.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005860:Germany, West; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D011230:Precancerous Conditions / Q000175:diagnosis; D011446:Prospective Studies; D012737:Sex Factors; D014062:Tongue Neoplasms / Q000175:diagnosis
vernacular_title: Prädilektionsstellen von Leukoplakien und Karzinomen der Mundschleimhaut.