The definitive identification of the lignans trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol in human and animal urine.
The definitive identification of the first lignans to be found in humans and animals is described. Gas chromatography--mass spectrometry, n.m.r. spectroscopy, i.r. spectroscopy and chemical techniques were employed to establish the structures of two lignans as trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone and 2,3-bis(3-hydroxybenzyl)butane-1,4-diol. Both compounds are essetially racemic. Evidence was also found for several methoxy analogues of these lignans in the vervet monkey.
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000652:urine*; D000818:Animals; D002072:Butylene Glycols / Q000302:isolation & purification / Q000652:urine*; D055598:Chemical Phenomena; D002621:Chemistry; D002522:Chlorocebus aethiops; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005260:Female; D005663:Furans / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D017705:Lignans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011247:Pregnancy
D002072:Butylene Glycols; D005663:Furans; D017705:Lignans; C029498:2,3-bis(3'-hydroxybenzyl)butane-1,4-diol; D015107:4-Butyrolactone; C029497:2,3-bis(3'-hydroxybenzyl)butyrolactone