Results of sputum, cytology among workers exposed to vinyl chloride monomer and to poly(vinyl chloride).
The results of systematic cytological sputum examinations of 3,380 Italian VC-PVC industry workers and of 2,287 workers in other industries at different potential risk and chosen as control groups are reported. The results indicate an increase in cellular abnormalities and dysplasias in the epithelium of the respiratory tract among VC-PVC workers. These data are in line with experimental results showing that VC produces lung tumors in mice and with early epidemiological evidence among exposed workers.
D006801:Humans; D006965:Hyperplasia; D007558:Italy; D008175:Lung Neoplasms / Q000139:chemically induced / Q000473:pathology*; D008679:Metaplasia; D009784:Occupational Diseases / Q000139:chemically induced / Q000473:pathology*; D011143:Polyvinyl Chloride / Q000009:adverse effects*; D011145:Polyvinyls / Q000009:adverse effects*; D012137:Respiratory System / Q000187:drug effects / Q000473:pathology; D013183:Sputum / Q000166:cytology*; D014752:Vinyl Chloride / Q000009:adverse effects*; D014753:Vinyl Compounds / Q000009:adverse effects*
D011145:Polyvinyls; D014753:Vinyl Compounds; D011143:Polyvinyl Chloride; D014752:Vinyl Chloride