Clinical features of 53 cases with pustulotic arthro-osteitis.
We have described clinical features of 53 cases with pustulotic arthro-osteitis. Anterior chest wall symptoms such as intersterno-costoclavicular or manubriosternal lesions were observed in all of 53 cases. Spondylitis or spondylodiscitis was found in 18 cases. Sacroiliitis resembling ankylosing spondylitis was seen in 7 cases. Peripheral inflammatory arthritis was seen in 14 cases, which were of nonerosive, of oligoarthritis type, and cured within 1 to 2 months, leaving no residue. HLA B27 was never found, and RAW factor was negative. Histological examinations revealed nonspecific chronic inflammation of bone and soft tissue. Pustulotic arthro-osteitis is apparently distinct from known rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and Reiter's disease. We have proposed that this condition should be classified as a member of the "seronegative spondylo-arthritis' group as designated by Wright and Moll.
D000328:Adult; D000368:Aged; D001168:Arthritis / Q000145:classification / Q000150:complications*; D002968:Clavicle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010000:Osteitis / Q000145:classification / Q000150:complications*; D012272:Ribs; D012871:Skin Diseases / Q000150:complications*; D013166:Spondylitis / Q000145:classification / Q000150:complications; D013167:Spondylitis, Ankylosing / Q000145:classification / Q000150:complications; D013492:Suppuration / Q000150:complications