[Behavioral teratogenesis. A new aspect of the pathology of prenatal development (author's transl)].
It has now been shown that, in the absence of malformation, functional disorders can exist, especially in the central nervous system as a result of diverse maternal and even paternal assaults on the developing conceptus. These disorders which are compatible with life include intellectual, behavioral and sensory-motor deficits. The causitive factors may be of toxogenic, dietetic or iatrogenic origin and may affect the conceptus differently according to its sex. A terminology corresponding to these more recent aspects of teratology is suggested, a distinction being made between morpho- and physio-teratogenic factors. In the framework of this terminology, certain practical aspects are envisaged: the dose of the causitive agent, the existence of a susceptible period during development, the existence of purely physio-teratogenic agents and the aspects of study methods. Finally, certain factors which can affect the optimum quality of offspring are described.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D001519:Behavior; D002653:Child Behavior Disorders / Q000209:etiology; D000013:Congenital Abnormalities / Q000209:etiology* / Q000517:prevention & control; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012737:Sex Factors
La physio-tératogenèse du comportement. Un nouvel aspect de la pathologie du développement prénatal.