Neonatal enterobacter suppurative arthritis and osteomyelitis.
Suppurative arthritis of the right knee and osteomyelitis of the adjacent femur complicated a urinary tract infection in an 18-day-old infant with a posterior urethral valve causing urinary flow obstruction. Initially cephalosporine sensitive Enterobacter caused the urinary tract infection. Shortly following cephazolin therapy, cephalosporine resistant Enterobacter microorganisms were isolated both from the urine and the knee joint fluid. These two infections were successfully treated with a combination of gentamicin and Co-trimoxazole. Gram-negative bacteria should be considered among the pathogens in neonatal osteoarticular infections, particularly if a urinary tract infection co-exists.
D001170:Arthritis, Infectious / Q000209:etiology*; D004756:Enterobacteriaceae Infections / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology*; D008297:Male; D010019:Osteomyelitis / Q000209:etiology*; D014552:Urinary Tract Infections / Q000150:complications*