title: Process-dependent risk of delayed health effects for welders.
abstract: In most industrialized countries large numbers of workers are exposed to welding fumes. Although the general pattern of welders' health may not significantly differ from that of workers in other dusty industrial occupations which demonstrate elevated incidence of respiratory tract diseases with long latency periods, the extremely wide range of substances at potentially high concentrations produced by various welding technologies may give rise to undetected process-specific high-risk working conditions: ("hot spots"). The origin, prevalence and range of magnitude of such hot spots, especially for cancer of the respiratory tract, is discussed, with emphasis placed on the assessment of risk resulting from exposure to Cr(VI) and Ni accompanying the use of various technologies for the welding of stainless and high alloy steels. The wide variation of health effects found within the industry, however, indicates the need for a standard protocol for future epidemiological studies, as well as for the development of suitable methodologies for experimental risk assessment.
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000818:Animals; D002857:Chromium / Q000633:toxicity; D006801:Humans; D009152:Mutagenicity Tests; D009532:Nickel / Q000633:toxicity; D009784:Occupational Diseases / Q000139:chemically induced*; D011009:Pneumoconiosis / Q000209:etiology*; D012129:Respiratory Function Tests; D012142:Respiratory Tract Neoplasms / Q000139:chemically induced; D012306:Risk; D012806:Siderosis / Q000209:etiology*; D014896:Welding
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D002857:Chromium; D009532:Nickel