An attempt to use the Tc-99m-thiodisuccinic acid (TDSA) complex in renoscintigraphy. I. Preparation of the complex.
Attempts to apply thiodisuccinic acid for assessment of kidney function prompted a study on optimal conditions of labelling the compound with Tc-99m. The optimal pH, incubation time, temperature at labelling and amounts of necessary reagents were determined which permit to obtain Tc-99m-TDSA complex of 97% purity. An appropriate Kit was developed for ex promptu preparation of the complex.
D007553:Isotope Labeling; D015609:Organotechnetium Compounds; D011866:Radioisotope Renography; D013386:Succinates; D013667:Technetium
D015609:Organotechnetium Compounds; D013386:Succinates; C034462:technetium Tc 99m-thiodisuccinic acid; C034463:2,2-thiodisuccinic acid; D013667:Technetium