title: [Evaluation of serum BuChe activity during polychemotherapy based on COP and C-MOPP protocols].
abstract: The Authors have evaluated the serum cholinesterase activity in patients subjected to 2 different schemes of polychemotherapy: COP (CTX, VCR, Prednisone) and C-MOPP (CTX, VCR, PCZ, Prednisone). The two schemes involve the administration of cyclophosphamide that, as has already been proved, significantly lowers serum cholinesterase level after only a few hours. The Authors have observed that the combination of cyclophosphamide with other antiblastic drugs or a longer treatment have little influence on the down curve of the serum cholinesterase in relation to what they have observed after treatment with cyclophosphamide alone.
mesh_terms: D002802:Cholinesterases / Q000097:blood*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000201:enzymology; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D011241:Prednisone / Q000627:therapeutic use; D011344:Procarbazine / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D011344:Procarbazine; D014750:Vincristine; D003520:Cyclophosphamide; D002802:Cholinesterases; D011241:Prednisone
vernacular_title: Valutazione dell'attività della BuChe sierica in corso di polichemioterapia con protocolli COP e C-MOPP.