title: Reactive metabolites as key intermediates in pharmacologic and toxicologic responses: examples from chemical carcinogenesis.
mesh_terms: D000477:Alkylating Agents / Q000378:metabolism; D000818:Animals; D000840:Anisoles / Q000378:metabolism; D001711:Biotransformation; D002273:Carcinogens; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000139:chemically induced; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism
chemical_list: D000477:Alkylating Agents; D000840:Anisoles; D002273:Carcinogens; D004364:Pharmaceutical Preparations; D011506:Proteins; C014037:1'-hydroxyestragole