[Hepatic function in the clinical spectrum of Hansen's disease].
The liver function was studied in 100 hanseniasis patients. They were classified in the following 10 groups: quiescent LL (20 patients), quiescent BL (13 patients), quiescent BB (7 patients), quiescent BT (9 patients), quiescent TT (12 patients), reactional LL (12 patients), reactional BL (10 patients), reactional BB (7 patients), reactional BT (5 patients), reactional TT (5 patients); a comparison was made with a control group (10 healthy individuals). It was found a hyperproteinemia with high levels of globulin and normal levels of albumin in the serum of all clinical forms, and a typical pattern of "light damage hepatic cells" with raised in the enzymatic activity of GOT, GPT and alkaline phosphatase with no changes in turbidity tests and bilirrubinemia, in all reactional patients. The physiopathology of this problem and the types III and IV hypersensitivity phenomena are discussed.
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001798:Blood Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D007918:Leprosy / Q000201:enzymology / Q000503:physiopathology*; D008099:Liver / Q000503:physiopathology*; D008111:Liver Function Tests; D008297:Male; D012709:Serum Albumin / Q000032:analysis; D012712:Serum Globulins / Q000032:analysis
D001798:Blood Proteins; D012709:Serum Albumin; D012712:Serum Globulins; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin
La función hepática a través del espectro clínico de la hanseniasis.