Effect of tenotomy and denervation on the early post-exercise glycogen recovery in skeletal muscles of the rat.
The role of passive tension and innervation in the early (1 and 3 h) post-exercise glycogen repletion was studied in different types (fast-twitch-glycolytic (FG), fast-twitch-oxidative-glycolytic (FOG) and slow-twitch-oxidative (SO) rat skeletal muscles. Immediately after a 30 min exercise the rats were anaesthetized and the muscles were subjected to the following surgical procedures: 1) left intact, 2) tenotomized, 3) denervated, 4) tenotomized and denervated. A group of resting rats was handled in the same way. It was found that tenotomy had no effect on glycogen levels in the muscle of resting rats. It, however, delayed the postexercise glycogen repletion in the FOG muscle. Denervation lowered the resting glycogen level only in the FG muscle. It resulted in further reduction of the glycogen level one hour after the exercise in this muscle. In the 3rd hour after the exercise the glycogen level in FG-denervated muscle was equal to that in the intact one. In the FOG and SO muscle denervation affected neither the resting glycogen level nor its recovery after the exercise.
D000818:Animals; D006003:Glycogen / Q000378:metabolism*; D008297:Male; D009121:Muscle Denervation; D009132:Muscles / Q000378:metabolism*; D010084:Oxidation-Reduction; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D013710:Tendons / Q000502:physiology*
D006003:Glycogen