title: Assignment of the glyoxalase II gene (HAGH) to human chromosome 16.
abstract: The human and rodent forms of glyoxalase II (Hydroxyacylglutathione hydrolase, HAGH) can readily be separated by starch gel electrophoretic procedures. Fifty-one human-rodent somatic cell hybrid clones were examined for their human HAGH and for human enzyme markers whose genes are encoded on each autosome and the X chromosome. Sixteen clones were also examined for their human karyotypes. Human glyoxalase II segregated only with chromosome 16, demonstrating that the gene is located on this chromosome.
mesh_terms: D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002902:Chromosomes, Human, 16-18 / Q000648:ultrastructure*; D006224:Cricetinae; D003412:Cricetulus; D004592:Electrophoresis, Starch Gel; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure; D008168:Lung; D051379:Mice; D008809:Mice, Inbred C3H; D012867:Skin; D013869:Thiolester Hydrolases / Q000235:genetics*; D000099301:Hydroxyacylglutathione Hydrolase
chemical_list: D013869:Thiolester Hydrolases; D000099301:Hydroxyacylglutathione Hydrolase