Predictive value of lymphocytotoxic test and platelet aggregometry for the effect of transfused platelet concentrates.
Sera of patients with thrombocytopenic diathesis before platelet transfusion were evaluated using donor's platelets in the aggregometry test the donor's lymphocytes in the lymphocytotoxicity test. In most cases the results of both tests were in agreement, although sometimes, despite strongly positive results of LCTT, the Agr was negative. Both tests showed a similar value for the prediction of the effectiveness of platelet concentrates: Agr in 80% and LCTT in 71% of cases.
D001803:Blood Transfusion; D005188:False Negative Reactions; D005189:False Positive Reactions; D006474:Hemorrhagic Disorders / Q000097:blood / Q000276:immunology / Q000628:therapy*; D006650:Histocompatibility Testing; D006801:Humans; D010974:Platelet Aggregation; D010976:Platelet Count; D017713:Platelet Transfusion; D013921:Thrombocytopenia / Q000097:blood / Q000276:immunology / Q000628:therapy*