[Metabolic and circulatory aspects of hypothermic perfusion of human kidney cancers].
In this study a report is made on the hypothermal perfusion of 15 renal tumours. Protein synthesis by incorporation of 14C leucine, lipide synthesis by conversion of 14C mevalonic acid and the activity of the sodium-potassium pump by incubation of sections of tissue were used as parameters of the vitality of the tissue. Circulation was studied before and after perfusion by means of angiography and the microsphere technique. After 6 days of perfusion the tumour tissue is found to be less vital in comparison with the renal cortex.
D003080:Cold Temperature; D006801:Humans; D007680:Kidney Neoplasms / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis; D009363:Neoplasm Proteins / Q000096:biosynthesis; D010477:Perfusion; D011188:Potassium / Q000378:metabolism; D012079:Renal Circulation; D012964:Sodium / Q000378:metabolism
D008055:Lipids; D009363:Neoplasm Proteins; D012964:Sodium; D011188:Potassium
Metabolische und zirkulatorische Aspekte der hypothermen Perfusion von humanen Nierenkarzinomen.