A follow-up study of children with food allergy. Clinical course in relation to serum IgE- and IgG-antibody levels to milk, egg and fish.
Eighty-two children with food sensitivity were followed-up for 2-5 years. Most children showed a decreasing sensitivity and the clinical course of food allergy seemed to reflect the course of the humoral immune responses to the offending foods. The occurrence of IgE- and IgG-antibodies paralleled in most cases. However, an early, high IgG/IgE food antibody ratio seemed to be a good prognostic sign, indicating a possible blocking capacity of IgG-antibodies.
D000293:Adolescent; D000818:Animals; D001249:Asthma / Q000209:etiology / Q000276:immunology; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D003231:Conjunctivitis / Q000209:etiology / Q000276:immunology; D004485:Eczema / Q000209:etiology / Q000276:immunology; D004529:Egg White / Q000009:adverse effects*; D005399:Fishes / Q000276:immunology; D005500:Follow-Up Studies; D005512:Food Hypersensitivity / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D007073:Immunoglobulin E / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007136:Immunoglobulins / Q000096:biosynthesis*; D007782:Lactoglobulins / Q000276:immunology; D008892:Milk / Q000276:immunology*; D010059:Ovomucin / Q000276:immunology; D012220:Rhinitis / Q000209:etiology / Q000276:immunology
D007074:Immunoglobulin G; D007136:Immunoglobulins; D007782:Lactoglobulins; D010059:Ovomucin; D007073:Immunoglobulin E