title: Correlation of proliferation of lung epithelium with intramuscular sensitization and complement-fixing antibody to respiratory syncytial virus in the golden hamster.
abstract: Intramuscular sensitization of hamsters with several forms of respiratory syncytial virus (RSv) caused proliferation of lung epithelium. In contrast, intranasal injection of live virus rarely resulted in this phenomenon. A correlation existed between proliferation of lung epithelium and presence of complement-fixing antibody, but not between lung disease and delayed skin reactions. Complement-fixing antibody to RSv was found to be independent of the influence of the thymus.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D002455:Cell Division; D003168:Complement Fixation Tests; D006224:Cricetinae; D004848:Epithelium / Q000473:pathology; D006968:Hypersensitivity, Delayed; D007114:Immunization; D008168:Lung / Q000276:immunology* / Q000473:pathology; D008213:Lymphocyte Activation; D008647:Mesocricetus; D012136:Respiratory Syncytial Viruses / Q000276:immunology*; D010253:Respirovirus Infections / Q000276:immunology; D013934:Thymectomy
chemical_list: D000914:Antibodies, Viral