Immunological characteristics of cells infiltrating sponge-matrix allografts in rats.
The morphological and functional characterization of cells infiltrating sponge-matrix allografts was done in rats. A higher percentage of esterase positive cells in the allografts already on day 1, with a gradual increase until day 7, was found. There was also a rise in percentage of esterase positive cells in peripheral blood of the allograft recipients. A higher percentage of phagocytic cells in the allografts on day 1, compared to syngeneic grafts, and a gradual rise during the ensuing six days were observed. These findings indicate the possibility of early recognition of alloantigen in the graft by monocytes and macrophages.
D000818:Animals; D002452:Cell Count; D005260:Female; D006084:Graft Rejection; D008264:Macrophages / Q000502:physiology*; D008297:Male; D008954:Models, Biological; D009000:Monocytes / Q000502:physiology*; D010587:Phagocytosis; D051381:Rats; D013997:Time Factors; D014184:Transplantation, Homologous