EA-rosette test in cervical cell suspensions.
Use of the EA-rosette test to detect the presence or absence of cells with an Fc receptor is proposed as a method of screening for cancerous cells and cells of carcinoma in situ in suspensions of cervical cell populations, The EA-rosette test was performed on cervical cell suspensions from 2,437 patients. In 54% the rosette test was negative; i.e., no EA rosettes were observed in the cervical cell suspensions. The EA-rosette test was positive in 46% of the cases, within which most cells with severe dysplastic and carcinomatous features were found. The predictive value for the negative EA-rosette test was 99.8%.
D002278:Carcinoma in Situ / Q000175:diagnosis; D005260:Female; D006801:Humans; D011961:Receptors, Fc / Q000032:analysis*; D012397:Rosette Formation; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology
D011961:Receptors, Fc