title: High efficiency haemofiltration (ultrafiltration of more than 250ml/min for two hours) in eight uraemic patients.
abstract: In eight uraemic patients a haemofiltration of very high efficiency was carried out from a double extracorporeal circuit set up via an arteriovenous fistula. The weight of the patients was kept constant throughout the session. The average ultrafiltration flow rate was 274ml/min; the total ultrafiltration volume was 32.9L/min. The clinical tolerance was very good. The loss of efficiency associated with the magnitude of the ultrafiltration volume and with the diffusion delay of the removed molecules was evaluated at 9 per cent for urea and 17 per cent for creatinine. In spite of a considerable phosphorus depletion no severe hypophosphoraemia was observed; the stable value of the phosphoraemia between the 90th and the 120th minute of the session suggests the existence of a physico-chemical balance around the value of 0.74mmol/L.
mesh_terms: D000328:Adult; D001769:Blood; D003404:Creatinine; D005260:Female; D006801:Humans; D008297:Male; D010758:Phosphorus / Q000097:blood; D014462:Ultrafiltration / Q000379:methods*; D014508:Urea; D014511:Uremia / Q000097:blood / Q000628:therapy*
chemical_list: D010758:Phosphorus; D014508:Urea; D003404:Creatinine