title: [Lectins, toxins and immunotoxins].
abstract: A definition and classification of lectins (carbohydrate-binding (glyco)proteins) is given on the basis of new data and experimental results. Especially the biological role of bacterial, vertebrate and sponge lectins is discussed. The lectin-toxin combination offers an excellent model not only for studying adhesion to and penetration through the cell membrane, but also for hybridization with antibody fragments showing anti-tumor specificity.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D000912:Antibodies, Neoplasm / Q000276:immunology; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability; D002772:Cholera Toxin / Q000378:metabolism; D005677:G(M1) Ganglioside / Q000378:metabolism; D037102:Lectins / Q000145:classification* / Q000276:immunology / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011817:Rabbits; D014118:Toxins, Biological / Q000378:metabolism*
chemical_list: D000912:Antibodies, Neoplasm; D037102:Lectins; D014118:Toxins, Biological; D005677:G(M1) Ganglioside; D002772:Cholera Toxin; D000262:Adenylyl Cyclases
vernacular_title: Lektine, Toxine und Immunotoxine.