[Effect of Complamin on fibrinolysis and platelet aggregation in the aged].
Investigated were the behaviour of platelet aggregation and fibrinolytic activity of the blood, under the influence of different doses of Complamin, and its effect in vitro on platelet aggregation. We have shown that platelet aggregation diminished only slightly after intravenous injection of Complamin, but the ADP-and collagen-induced aggregation in vitro were inhibited. Except that, fibrinolytic activity in the blood had been induced, but the degree and continuance of fibrinolysis were limited depending on the patient. There was no significant modifications of examined tests after prolonged intravenous infusion of the drug.
D000368:Aged; D005260:Female; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D013806:Theophylline / Q000031:analogs & derivatives*; D014971:Xanthinol Niacinate / Q000494:pharmacology*
D014971:Xanthinol Niacinate; D013806:Theophylline
Efekat Complamina na fibrinolizu i agregaciju trombocita u starijih osoba.