Depressed PHA--induced lymphocyte transformation in women taking oral contraceptives.
The transformation of lymphocytes in response to the mitogen phytohemagglutinin (PHA) was determined in 30 women taking oral contraceptives (O.C.V.) and in 10 women of an age-matched control group. The group taking oral contraceptives demonstrated significant depression of their response to PHA as compared to the control group.
D000328:Adult; D003276:Contraceptives, Oral / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D010835:Phytohemagglutinins / Q000494:pharmacology
D003276:Contraceptives, Oral; D010835:Phytohemagglutinins