Parathyroid hormone binding to epithelium of the human lens.
Cell homogenates from human lens epithelium express in binding site for Parathyroid hormone. Kinetic data reveal an affinity/dissociation constant to Kd 17.5 x 10(-11) M and a maximal binding of Bmax 15 x 10(11) M. These data are comparable to previously tested tissues as lymphocytes or renal plasma membranes. No differences can be observed for the association characteristics between senile and juvenile lenticular epithelial cells.
D000328:Adult; D000367:Age Factors; D001665:Binding Sites; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D007908:Lens, Crystalline / Q000378:metabolism*; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000378:metabolism*
D010281:Parathyroid Hormone