[Comparative radioautographic analysis of protein synthesis and slow transport in the axons of rabbit mono- and binuclear neurocytes].
For comparative investigation of protein synthesis in perikaryons and its slow transport into axons of uni- and double-nuclear cells of the superior cervical sympathetic ganglion in a normal mature rabbit under conditions of colchicin administration, the method of radioautography was applied. Indices on intensity of protein synthesis in perikaryons and those of its migration rate into the processes were demonstrated to be nearly identical for the uni- and double-nuclear cells. Colchicin did not affect the intensity of the protein synthesis in the perikaryon, but it similarly inhibited transport of the slowly migrating protein into the processes of the uni- and double-nuclear neural cells.
D000818:Animals; D001345:Autoradiography; D001369:Axons / Q000187:drug effects / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism*; D003078:Colchicine / Q000494:pharmacology; D005728:Ganglia, Sympathetic / Q000187:drug effects / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*; D011817:Rabbits
D009419:Nerve Tissue Proteins; D003078:Colchicine
Sravnitel'nyĭ radioavtograficheskiĭ analiz sinteza i medlennogo transporta belka v aksony odno- i dvuiadernykh neĭrotsitov krolika.