Zinc concentrations in human plasma and in rat plasma and tissues during lithium administration.
Zinc concentrations, determined with atomic absorption spectrophotometry, did not differ significantly in plasma from manic-depressive patients about to start lithium treatment and in patients having been in lithium treatment for six months or 1-2 years. Plasma zinc concentrations and zinc concentrations in liver, muscle, kidney, bone, and skin did not differ in control rats and rats given lithium with the food for four weeks.
D000818:Animals; D001714:Bipolar Disorder / Q000097:blood / Q000188:drug therapy; D006801:Humans; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution; D015032:Zinc / Q000097:blood / Q000378:metabolism*
D008094:Lithium; D015032:Zinc