title: [Does precurarization prevent the increase of serum potassium after administration of succinylcholine in risk patients? - a case report- (author's transl)].
abstract: There are different opinions about the efficiency of preventing the succinylcholine-induced increase of serum potassium by precurarization. The following case report demonstrates that this method is not practicable in risk patients. A case of severe cerebral trauma is reported, in whom after precurarization with 2,0 mg diallyl-nortoxiferine and with 1.5 mg pancuronium, too, there was an increase of a normal serum potassium level up to 9.35 respectively 9.20 mEq/l about 1-2 minutes after injection of succinylcholine. 20 minutes after the injection serum potassium decreased to a normal level again. Only a short lasting bradycardia was noticed during the hyperkaliaemic period. Similar results reported in the anaesthesiologic literature are discussed.
mesh_terms: D000443:Alcuronium / Q000008:administration & dosage* / Q000009:adverse effects; D000771:Anesthesia, Intravenous; D001930:Brain Injuries / Q000601:surgery; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010197:Pancuronium / Q000008:administration & dosage / Q000009:adverse effects; D011188:Potassium / Q000097:blood*; D011229:Preanesthetic Medication; D013390:Succinylcholine / Q000009:adverse effects; D014117:Toxiferine / Q000031:analogs & derivatives*
chemical_list: D014117:Toxiferine; D013390:Succinylcholine; D010197:Pancuronium; D011188:Potassium; D000443:Alcuronium
vernacular_title: Verhindert die Präkurarisierung den succinylcholinbedingten Serumkaliumanstieg bei Risikopatienten? -ein Fallbericht-.