Prediction of drug-drug interaction from in vitro plasma protein binding and metabolism. A study of tolbutamide-sulfonamide interaction in rats.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D004347:Drug Interactions; D006207:Half-Life; D008297:Male; D008433:Mathematics; D008657:Metabolic Clearance Rate; D051381:Rats; D011919:Rats, Inbred Strains; D013412:Sulfadimethoxine / Q000097:blood; D013420:Sulfamethoxazole / Q000097:blood; D013426:Sulfaphenazole / Q000097:blood; D013449:Sulfonamides / Q000097:blood*; D014044:Tolbutamide / Q000097:blood*
D001798:Blood Proteins; D013449:Sulfonamides; D013426:Sulfaphenazole; D013412:Sulfadimethoxine; D014044:Tolbutamide; D013420:Sulfamethoxazole