title: Comparison of renal ornithine transcarbamylase activities within different chicken breeds.
abstract: Comparisons were made of the renal ornithine transcarbamylase (OTC) activities within different groups of chickens including Japanese native breeds. OTC activities varied markedly within these groups. The Cochin Bantam breed and White Leghorn B line had an especially high activity, about 400 units/g of kidney, in contrast to two Japanese native breeds, Japanese Game (white variety) and Banshuu Gashiwa, and the California Gray breed, which showed a very low activity, the values being almost undetectable. In crossing experiments using the California Gray breed as a tester strain, Cochin Bantam OTC represents a simple autosomal incompletely dominant trait similar to the White Leghorn B line OTC. Kinetic studies using partially purified OTC preparations from the White Leghorn B line and Cochin Bantam breed revealed that both enzymes were identical for a variety of enzymic characteristics. In light of these results, the physiological significance of chick kidney OTC is discussed.
mesh_terms: D000818:Animals; D002645:Chickens / Q000235:genetics*; D003433:Crosses, Genetic; D014644:Genetic Variation; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D009954:Ornithine Carbamoyltransferase / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity
chemical_list: D009954:Ornithine Carbamoyltransferase