title: Complex syndrome in a young girl: Wolfram's syndrome?
abstract: The combination of juvenile diabetes mellitus, optic atrophy, perceptive hearing loss, diabetes insipidus and atonia of the urinary tract and bladder seems to constitute a distinct syndrome. In certain cases delayed puberty is also mentioned but this has not been considered as part of the syndrome.
mesh_terms: D000293:Adolescent; D003919:Diabetes Insipidus / Q000150:complications*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D034381:Hearing Loss / Q000150:complications*; D006316:Hearing Loss, High-Frequency / Q000150:complications*; D006801:Humans; D009896:Optic Atrophy / Q000150:complications*; D013577:Syndrome; D001745:Urinary Bladder Diseases / Q000150:complications*; D014570:Urologic Diseases / Q000150:complications*