Proliferative response of lymphocytes of normal individuals to wheat proteins (gliadins).
Preparations of gliadin, extracted from wheat gluten, were shown to stimulate a proliferative response by lymphocytes of normal donors. Not all donors responded to gliadin. In all but one case responder or non-responder status remained consistent on retesting. There was no association of ability to respond with HLA A or B type.
D004306:Dose-Response Relationship, Immunologic; D005903:Gliadin / Q000276:immunology*; D006680:HLA Antigens; D006801:Humans; D008213:Lymphocyte Activation; D010940:Plant Proteins / Q000276:immunology*; D013745:Tetanus Toxoid / Q000276:immunology; D014373:Tuberculin / Q000276:immunology; D014508:Urea / Q000494:pharmacology
D006680:HLA Antigens; D010940:Plant Proteins; D013745:Tetanus Toxoid; D014373:Tuberculin; D014508:Urea; D005903:Gliadin