title: [Effectiveness of Cendehill vaccine in the prophylaxis of rubella embryopathy (author's transl)].
abstract: Recent rubella infection (rubella-specific IgM positive, raised rubella complement fixation reaction and haemagglutination inhibition) could be demonstrated during a prophylactic investigation in early pregnancy in a 19-year-old girl previously successfully immunised with Cendehill vaccine (seroconversion). Due to the seroconversion demonstrated during school age no interruption was performed. The newborn baby had a rubella-HAI-antibody titre in the umbilical blood of 1 : 640, but no rubella-specific IgM antibodies (also at later controls). Rubella infection of the child in utero could thud be excluded. This for the first time confirms the protective effect of the Cendehill vaccine in the prophylaxis of rubella embryopathy.
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D005315:Fetal Diseases / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000150:complications; D012409:Rubella / Q000150:complications*; D012411:Rubella Vaccine
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M; D012411:Rubella Vaccine
vernacular_title: Wirksamkeit der Cendehill-Vakzine in der Prophylaxe der Rötelnembryopathie.