title: Quantitative study of the rabbit aortic endothelium using vascular casts.
abstract: A quantitative study of the en face size and shape of rabbit endothelial cells from the ventral mid-thoracic and ventral infrarenal abdominal aorta has been carried out in 6 rabbits. Photomicrographs were taken from vascular casts of the rabbit aorta and the endothelial cell outlines were analyzed quantitatively using a digitizer and digital computer. The morphology of the endothelial cells was described using 8 calculated parameters (area, perimeter, length, width, angle of orientation, width:length ratio, axis intersection ratio and shape index). The endothelial cells in both locations had the same surface area (P greater than 0.30); however, the cells in the abdominal aorta were longer (P less than 0.01) and narrower (P less than 0.01) than those in the thoracic aorta. This fact is reflected by the smaller value for the shape index and width : length ratio in the abdominal aorta (P less than 0.01). Cells in both the thoracic and abdominal aorta were aligned with the flow direction.
mesh_terms: D000818:Animals; D001011:Aorta / Q000166:cytology*; D001012:Aorta, Abdominal / Q000166:cytology; D001013:Aorta, Thoracic / Q000166:cytology; D004727:Endothelium / Q000166:cytology; D006439:Hemodynamics; D008297:Male; D011817:Rabbits