title: [Effect of additional administration of essential amino acids on assimilability of casein hydrolysate in rats with toxic hepatitis].
abstract: The effect of certain amino acids on assimilability of casein hydrolysate was studied in albino rats with toxic hepatitis. It is established that in case of this pathology casein hydrolysate is uncapable of correcting completely the disturbed protein and nucleic metabolism. An additional administration under these conditions of amino acids, methionine in particular, changes the negative nitrogeneous balance to the positive one, that evidences for an increase in assimilability of the introduced casein hydrolysate, lowers the excretion of amino nitorgen with urea and rises the DNA content in the liver tissue. Triptophan and lysine favour an increase in the protein content in the nuclei and mitochondria of hepatocytes.
mesh_terms: D000601:Amino Acids, Essential / Q000494:pharmacology*; D000818:Animals; D002364:Caseins; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism*; D004247:DNA / Q000378:metabolism; D004044:Dietary Proteins; D006868:Hydrolysis; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats
chemical_list: D000601:Amino Acids, Essential; D002364:Caseins; D004044:Dietary Proteins; D011506:Proteins; D004247:DNA
vernacular_title: Vliianie dopolnitel'nogo primeneniia nezamenimykh aminokislot na usvoiaemost' gidrolizata kazeina u krys s toksicheskim gepatom.