title: Failure of bethanechol denervation supersensitivity as a diagnostic aid.
abstract: A total of 33 patients who demonstrated detrusor areflexia during cystometry underwent the bethanechol denervation supersensitivity test. In each instance the presence or absence of a neurologic lesion was documented carefully by complete neurologic evaluation. Of the 21 patients with a neurogenic bladder there was a falsely negative rate of 24 per cent. Of the 12 patients without a neurogenic bladder the falsely positive rate was 50 per cent. It is concluded that a positive bethanechol test is not by itself indicative of neurogenic bladder nor does a negative test exclude this diagnosis.
mesh_terms: D000328:Adult; D000368:Aged; D001626:Bethanechol Compounds; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D001745:Urinary Bladder Diseases / Q000175:diagnosis*; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis*
chemical_list: D001626:Bethanechol Compounds