Autosomal recessive inheritance of atrichia congenita.
Two families, each with two sibs presenting atrichia congenita, were studied. Histopathological studies of scalp biopsies from affected revealed absence of hair follicles. The pedigree data were interpreted as corroborative of a previously postulated autosomal recessive pattern of inheritance.
D000505:Alopecia / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D010375:Pedigree; D012535:Scalp / Q000473:pathology