Potentiation of acoustic-trauma-induced audiogenic seizure susceptibility by salicylates in mice.
Combined exposure to noise and salicylates was found to produce greater acoustic trauma induced audiogenic seizure risk than exposure to the noise alone. The result suggests that salicylates could make the mouse cochlea more vulnerable to the traumatic action of noise.
D000161:Acoustic Stimulation / Q000009:adverse effects; D000818:Animals; D001241:Aspirin / Q000009:adverse effects*; D051379:Mice; D008807:Mice, Inbred BALB C; D012640:Seizures / Q000209:etiology*; D012980:Sodium Salicylate / Q000009:adverse effects*; D013268:Stimulation, Chemical
D001241:Aspirin; D012980:Sodium Salicylate