title: Design analyses of a new selective filtration system for removal of uremic toxins.
abstract: A new system for removal of uremic toxins is described, The system is based on selective removal of small (urea, creatinine) and large uremic toxins through a multimembrane filter/dialyzer unit. Theoretical calculations show that the system is capable of removing the desired range of molecules from uremic plasma, while retaining a large portion of non-toxic elements in the blood. The SElective DUal Filtration ARtificial Kidney can be optimized and assembled into a single compact unit, which is simple to use and requires minimal monitoring equipment. Preliminary clinical trials indicate that SEDUFARK is a feasible system for treatment of uremic patients.
mesh_terms: D005374:Filtration / Q000295:instrumentation; D006801:Humans; D007688:Kidneys, Artificial / Q000295:instrumentation*; D008433:Mathematics; D008954:Models, Biological