Myeloid and erythroid colony growth in non-anaemic patients with Fanconi's anaemia.
Myeloid and erythroid colony growth of the bone marrow and peripheral blood cells from one anaemic and four non-anaemic patients with Fanconi's anaemia were studied. Markedly decreased myeloid and erythroid colony growth was found in all five patients regardless of their haematological status. The decreased colony formation in non-anaemic patients with Fanconi's anaemia is thought to be due to an intrinsic cellular defect.
D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology*; D002648:Child; D003114:Colony-Forming Units Assay; D004900:Erythroblasts; D005199:Fanconi Anemia / Q000097:blood / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009000:Monocytes