Procarbazine-induced skin reactions in Hodgkin's disease and other malignant lymphomas.
A total of 44 patients with Hodgkin's disease and 23 patients with non-Hodgkin malignant lymphoma were treated with MOPP-combination chemotherapy. 4 patients with Hodgkin's disease and 8 with non-Hodgkin lymphoma developed urticaria or maculo-papular rash. This frequency of hypersensitivity reactions is higher than that expected from the few cases reported in the literature.
D004342:Drug Hypersensitivity / Q000209:etiology*; D006689:Hodgkin Disease / Q000188:drug therapy*; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy*; D011344:Procarbazine / Q000009:adverse effects / Q000627:therapeutic use; D014581:Urticaria / Q000139:chemically induced*
D011344:Procarbazine