Chloral hydrate overdose and cardiac arrhythmias.
Two cases of chloral hydrate overdosage were associated with multiform ventricular tachycardia. Both were refractory to a number of antiarrhythmics, but responded to propranolol administration. Two of nine other cases reported in the literature also responded to beta-blocking agents. Mechanisms for the arrhythmia and its apparent response to beta blockade are discussed.
D000293:Adolescent; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D002697:Chloral Hydrate / Q000506:poisoning*; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D011433:Propranolol / Q000627:therapeutic use; D013610:Tachycardia / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy
D002697:Chloral Hydrate; D011433:Propranolol