Methyl methane sulfonate induced enhancement of Friend viral leukemogenesis.
Exposure to the chemical carcinogen, methyl methane sulfonate, enhanced leukemogenesis in mice given threshold doses of Friend leukemia virus, as shown by peripheral white blood cell counts, splenomegaly and survival.
D000818:Animals; D005260:Female; D005622:Friend murine leukemia virus / Q000472:pathogenicity*; D007942:Leukemia, Experimental / Q000139:chemically induced* / Q000382:microbiology; D007958:Leukocyte Count; D008741:Methyl Methanesulfonate / Q000008:administration & dosage / Q000009:adverse effects*; D051379:Mice; D013163:Splenomegaly
D008741:Methyl Methanesulfonate