Accidental administration of Syntometrine in adult dosage to the newborn.
The clinical course is described of an infant who accidentally received an adult dose of Syntometrine (synthetic oxytocin + ergometrine) at delivery. The infant soon became ill with convulsions and ventilatory failure, and later with water intoxication. Similar reported cases are reviewed and recommendations are given for the management of future cases.
D000059:Accidents; D004338:Drug Combinations; D004874:Ergonovine / Q000506:poisoning*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000139:chemically induced*; D010121:Oxytocin / Q000506:poisoning*; D012131:Respiratory Insufficiency / Q000139:chemically induced; D012640:Seizures / Q000139:chemically induced; D014869:Water Intoxication / Q000139:chemically induced
D004338:Drug Combinations; D010121:Oxytocin; D004874:Ergonovine