title: [Immunoreactive insulin and C-peptide in glucose tolerance disturbances in the relatives of diabetes mellitus patients].
abstract: The content of immunoreactive insulin (IRI) and of immunoreactive C-peptide (IRCP) was determined in the relatives of patients with juvenile diabetes mellitus and in healthy persons during the oral glucose tolerance test (GTT). The IRCP content was higher than the IRI content. The IRI and IRCP curves were identical in persons with normal and doubtful GTT results; these curves differed from those in patients with latent and manifest diabetes which were torpid in character. The coefficient of molar IRCP/IRI proportion differed in persons with pathological GTT results as compared with the normal.
mesh_terms: D000293:Adolescent; D000328:Adult; D002096:C-Peptide / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000235:genetics*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007330:Insulin Antibodies / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000097:blood*; D011236:Prediabetic State / Q000097:blood
chemical_list: D002096:C-Peptide; D007330:Insulin Antibodies; D010455:Peptides
vernacular_title: Immunoreaktivnyĭ insulin i C-peptid pri narusheniiakh tolerantnosti k gliukoze u rodstvennikov bol'nykh sakharnym diabetom.