Risk of stroke in asymptomatic persons with cervical arterial bruits: a population study in Evans County, Georgia.
A survey of the rural community in Evans County, Georgia, revealed cervical arterial bruits in 72 (4.4 per cent) of 1620 persons 45 years of age of older without previous stroke, transient ischemic attacks, or overt ischemic heart disease. The prevalence of such asymptomatic bruits increased with age and was greater in women and persons with hypertension. We estimated the risk of stroke associated with cervical bruits during a six-year follow-up period, taking age and blood pressure into account. The presence of asymptomatic bruits was associated with a significantly higher risk of stroke in men but not in women, with odds ratios of 7.5 and 1.6, respectively. Despite the high risk of stroke among men with bruits, the correlation between the location of the bruits and the type of subsequent stroke was poor. Moreover, cervical bruits in men were a risk factor for death from ischemic heart disease. We suggest that asymptomatic cervical bruits are an indication of systemic vascular disease and do not themselves justify invasive diagnostic procedures or surgical correction of underlying extracranial arterial lesions.
D000367:Age Factors; D000368:Aged; D001158:Arteries / Q000503:physiopathology; D001314:Auscultation; D002339:Carotid Arteries / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D003327:Coronary Disease / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005845:Georgia; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009333:Neck / Q000098:blood supply*; D012306:Risk; D012737:Sex Factors