Metastatic infiltration of nerves in the cavernous sinus.
Painful dysesthesia in association with ocular motor palsies characterized intraneural carcinomatous invasion in a 48-year-old man. Transcranial biopsy of the cavernous sinus stopped the pain; the specimen confirmed the diagnosis and provided the rationale for radiation therapy. One year after treatment, the patient was healthy and pain-free, with improved ocular motor function. The source of the carcinoma remains unknown.
D000010:Abducens Nerve / Q000000981:diagnostic imaging / Q000648:ultrastructure; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000648:ultrastructure; D002426:Cavernous Sinus / Q000000981:diagnostic imaging* / Q000648:ultrastructure; D002533:Cerebral Angiography; D003390:Cranial Nerve Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000648:ultrastructure; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure; D009886:Ophthalmoplegia / Q000000981:diagnostic imaging