A differential scanning calorimetry study of the interaction of gangliosides with peanut lectin, serotonin and daunomycin.
Thermotropic behaviour of human Tay-Sachs ganglioside and of mixed bovine brain gangliosides, before and after interaction with peanut lectin, serotonin and daunomycin, was investigated. Interaction of mixed brain gangliosides with peanut lectin or serotonin causes a decrease in the enthalpy of melting, whereas interaction of this lectin with Tay-Sachs ganglioside does not influence the enthalpy of melting. Serotonin causes a small increase in the enthalpy of melting of the Tay-Sachs ganglioside.
D010367:Arachis; D001923:Brain Chemistry; D002152:Calorimetry, Differential Scanning; D003630:Daunorubicin; D005677:G(M1) Ganglioside; D005732:Gangliosides; D006801:Humans; D037102:Lectins; D037121:Plant Lectins; D012701:Serotonin; D013661:Tay-Sachs Disease / Q000378:metabolism
D005732:Gangliosides; D037102:Lectins; D037121:Plant Lectins; D012701:Serotonin; D005677:G(M1) Ganglioside; D003630:Daunorubicin