Fluorescent light induces malignant transformation in mouse embryo cell cultures.
Fluorescent light induced a dose-dependent malignant transformation in mouse C3H10T1/2 cells. A plateau in the dose-response curve for transformation was correlated with that observed with ultraviolet light exposure. The similarity in the two dose-response patterns suggests that similar molecular processes may be involved in the induction of malignant transformation by the two types of radiation.
D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D002471:Cell Transformation, Neoplastic / Q000528:radiation effects*; D002478:Cells, Cultured; D004247:DNA / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004622:Embryo, Mammalian / Q000528:radiation effects; D005453:Fluorescence; D008027:Light; D051379:Mice; D011740:Pyrimidine Dimers / Q000528:radiation effects; D014466:Ultraviolet Rays
D011740:Pyrimidine Dimers; D004247:DNA