Mycetoma caused by microsporum audouinii. First reported case.
A 25-year-old black man had generalized tinea corporis for 19 years and had associated subcutaneous mycotic granuloma of the scalp and nape of the neck for 17 years. The dermatophyte from the skin was identified as Microsporum audouinii and responded to oral griseofulvin treatment. Biopsy specimens of the subcutaneous nodules revealed yellowish granules containing masses of irregularly septated hyaline hyphae with frequent vesicles. This fungus differed only in gross colonial morphology from the M. audouinii isolated from the skin and has also been identified as M. audouinii. The subcutaneous nodules were treated and controlled by amphotericin B and are still under treatment.
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008864:Microsporum / Q000302:isolation & purification*; D008271:Mycetoma / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D012867:Skin / Q000473:pathology; D014005:Tinea / Q000188:drug therapy / Q000473:pathology
D006118:Griseofulvin; D000666:Amphotericin B