Total synthesis of heterocyclic steroids, Part IV. Mass spectrometry in stereochemical determination of the C/D ring fusion geometry in some heteroaromatic steroids.
The mass spectral fragmentation pattern and the relative intensities of the fragment peaks of the D ring in some 8-dehydroheteroaromatic steroids were studied. Characteristic differences for the cis and trans isomers were ascertained and were used for the determination of the stereochemistry of thiasteroids of which only one isomer was obtained.
D045166:Estradiol Congeners; D007536:Isomerism; D008968:Molecular Conformation; D013057:Spectrum Analysis; D013256:Steroids; D013329:Structure-Activity Relationship
D045166:Estradiol Congeners; D013256:Steroids