[Effect of tetanus toxin on noradrenaline release from rat brain synaptosomes].
Purified tetanus toxin (TT) (80-800 Dlm/mg protein) releases both endogenous and exogenous (14)C-norepinephrine from the isolated nerve endings (synaptosomes) of the rat brain. Within the investigated range of concentrations TT does not suppress norepinephrine release induced by different ways of depolarizing the synaptosomes in vitro.
D000818:Animals; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D066298:In Vitro Techniques; D009638:Norepinephrine / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology; D051381:Rats; D013574:Synaptosomes / Q000032:analysis* / Q000378:metabolism; D013744:Tetanus Toxin / Q000494:pharmacology*
D013744:Tetanus Toxin; D010042:Ouabain; D009638:Norepinephrine
Vliianie stolbniachnogo toksina na vysvobozhdenie noradrenalina iz sinaptosom golovnogo mozga krys.