Bilateral optic atrophy caused by chronic oral ingestion and topical application of hexachlorophene.
A 31-year-old woman ingested hexachlorophene (pHisoHex) over a ten-month period. She developed bilateral optic atrophy with no other systemic evidence of neurotoxicity. This cases supports pathologists' findings that the optic nerve and chiasm are particularly sensitive to the poisonous effects of hexachlorophene.
D000284:Administration, Oral; D000287:Administration, Topical; D000328:Adult; D005260:Female; D006582:Hexachlorophene / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D009896:Optic Atrophy / Q000139:chemically induced*; D012651:Self Medication
D006582:Hexachlorophene