Radioactivity studies on 2 synovial specimens after radiation synovectomy with yttrium-90 silicate.
Synovial membranes surgically removed from the knees of 2 patients who had received radioactive yttrium-90 silicate have been examined. Autoradiographs showed that in both cases the activity was unevenly distributed over the synovium. One of the specimens, removed 7 weeks after administration of the isotope, was found to contain a slight degree of radioactivity, attributable in part to a long-lived radioactive contaminant.
D001172:Arthritis, Rheumatoid / Q000378:metabolism* / Q000532:radiotherapy; D001345:Autoradiography; D004340:Drug Contamination; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000032:analysis; D013583:Synovial Membrane / Q000032:analysis*; D015021:Yttrium Radioisotopes / Q000032:analysis* / Q000627:therapeutic use
D015021:Yttrium Radioisotopes