Therapeutic effectiveness and safety of outdated human red blood cells rejuvenated to restore oxygen transport function to normal, frozen for 3 to 4 years at -80 C, washed, and stored at 4 C for 24 hours prior to rapid infusion.
D000328:Adult; D000368:Aged; D000740:Anemia / Q000628:therapy; D001692:Biological Transport; D001793:Blood Preservation; D001803:Blood Transfusion; D004163:Diphosphoglyceric Acids / Q000097:blood; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D005615:Freezing; D006454:Hemoglobins; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000502:physiology*; D013696:Temperature; D013997:Time Factors
D004163:Diphosphoglyceric Acids; D006454:Hemoglobins; D010100:Oxygen