title: Studies on the efficacy of fenbendazole used in a divided dosage regime against strongyle infections in ponies.
abstract: The efficacy of a fenbendazole divided dose regime against immature stages of Trichonema spp, Strongylus vulgaris and Strongylus edentatus was evaluated. A group of 8 naturally infected 30 to 36-month-old ponies was divided into 2 equal groups on the basis of previous treatment and faecal egg counts, one group being treated with 7.5 mg/kg bwt of fenbendazole daily for 5 days. This treatment regime removed 80 per cent of migrating S vulgaris larvae, 100 per cent of migrating S edentatus larvae and 95 per cent of the mucosal stages of Trichonema spp. In addition, a virtual 100 per cent elimination of adult stages of large and small strongyles was obtained.
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000008:administration & dosage*; D005273:Fenbendazole / Q000008:administration & dosage* / Q000627:therapeutic use; D006736:Horses; D013319:Strongyle Infections, Equine / Q000188:drug therapy*; D013320:Strongyloidea / Q000187:drug effects
chemical_list: D001562:Benzimidazoles; D005273:Fenbendazole