Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice.
CBA/N mice carry a recessive mutation at the X-linked immune deficiency (xid) locus that precludes their response to certain thymus-independent (TI) antigens. We have determined that xid is situated on the X-chromosome between the genes Ta (tabby) and Hyp (hypophosphatemia), genetic distances being Ta-6.6 +/- 1.8-xid-12.2 +/- 2.3-Hyp.
D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005260:Female; D005787:Gene Frequency; D007153:Immunologic Deficiency Syndromes / Q000235:genetics*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA / Q000235:genetics*; D009154:Mutation; D011995:Recombination, Genetic; D014960:X Chromosome / Q000276:immunology