title: Cytology and colposcopy in the diagnosis and management of outpatients with cervical intraepithelial neoplasia.
abstract: One hundred consecutive outpatients seen in the colposcopy clinic of a private hospital had one or more Papanicolaou smears that suggested cervical atypia, dysplasia or carcinoma in situ. Of these 100 patients, 7% underwent a diagnostic cervical cone biopsy; 11% more had therapeutic conization. The accuracy of colposcopic examination with directed cervical biopsy within one level (under or over) of histologic findings was 88%; the cytologic accuracy within one level of histologic findings was 83%. The study showed that patients with cervical atypia at cytologic examination had dysplasia and carcinoma in situ at subsequent colposcopic cervical examination with directed biopsy.
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology; D003127:Colposcopy; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D065006:Papanicolaou Test; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014626:Vaginal Smears