Systemic animal external parasiticidal activity of perfluoroalkylbenzimidazoles and their aminoanilide precursors.
In vitro and in vivo efficacy data indicate that chemical activity is optimized at the 2 carbon chain length and that these compounds have injectable potency and spectrum of activity against major animal external parasite species.
D000813:Anilides / Q000494:pharmacology*; D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D004165:Diphtheria / Q000188:drug therapy; D004175:Diptera / Q000187:drug effects; D006168:Guinea Pigs; D007306:Insecticides; D007814:Larva / Q000187:drug effects; D013045:Species Specificity; D013329:Structure-Activity Relationship; D013987:Ticks / Q000187:drug effects
D000813:Anilides; D001562:Benzimidazoles; D007306:Insecticides