A technique for studying the structural detail of isolated human corneocytes.
A technique for the isolation of human stratum corneum cells from any depth within the horny layer is described. Examination of the cells by light, scanning and transmission electron microscope permits a detailed morphological profile of the plasma membrane to be constructed. It is suggested that the technique will be of particular value in determining the effect of chemical agents on the cellular components of the horny layer.
D002462:Cell Membrane / Q000648:ultrastructure; D002469:Cell Separation / Q000379:methods*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D012867:Skin / Q000166:cytology / Q000648:ultrastructure*