title: Prevention and control of hypertension by nutritional-hygienic means. Long-term experience of the Chicago Coronary Prevention Evaluation Program.
abstract: In the Chicago Coronary Prevention Evaluation Program (CPEP), 115 men had definite mild hypertension at entry; another 101 men had high-normal diastolic blood pressure (BP). The nutritional-hygienic nonpharmacologic CPEP regimen achieved years-long moderate weight loss, slowing of pulse rate, and reduction in serum cholesterol levels. Sustained falls in BP were recorded-about 10/13 mm Hg for hypertensive men, resulting in long-term normalization of BP, and about 7/4 mm Hg for men with high-normal BP at entry. Change in weight and change in BP were significantly correlated. Long-term improvements in eating and exercise habits yielding moderate sustained weight loss are apparently useful in preventing high BP in hypertension-prone persons and in controlling established "mild" hypertension.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D005247:Feeding Behavior; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011674:Pulse; D012306:Risk; D013997:Time Factors
chemical_list: D002784:Cholesterol