Lipoperoxide formation of lysosome due to hematoporphyrin and ultraviolet light irradiation.
The malondialdehyde (MDA) contents in rat liver lysosomes increased in vitro by 400 nm ultraviolet light irradiation in the presence of hematoporphyrin (HP), but no changes were observed without HP. The MDA formation under the presence of HP was prevented by addition of vitamin E as antioxidant.
D015104:3,4-Methylenedioxyamphetamine / Q000032:analysis; D000818:Animals; D000975:Antioxidants; D005260:Female; D006415:Hematoporphyrins / Q000494:pharmacology*; D066298:In Vitro Techniques; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism / Q000528:radiation effects; D008247:Lysosomes / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D014466:Ultraviolet Rays; D014810:Vitamin E / Q000494:pharmacology
D000975:Antioxidants; D006415:Hematoporphyrins; D008054:Lipid Peroxides; D014810:Vitamin E; D015104:3,4-Methylenedioxyamphetamine