title: Cold hypersensitivity after sympathectomy for Raynaud's disease.
abstract: Two patients with socially handicapping Raynaud's disease underwent bilateral upper thoracic sympathectomy. One to two days after the operation, both developed local hypersensitivity to cold in the form of a rebound. The cold hypersensitivity persisted in one of the patients, although complete degeneration of vasoconstrictor fibres was proven by absence of the sympathetic veno-arteriolar reflex after sympathectomy. Pre-operative sympathetic blockade could not predict the outcome of sympathectomy.
mesh_terms: D000328:Adult; D001794:Blood Pressure; D003080:Cold Temperature; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000628:therapy*; D013562:Sympathectomy / Q000009:adverse effects*; D014661:Vasoconstriction