title: [Importance of the growth hormone in regulating polynucleotide phosphorylase activity in the rat liver].
abstract: Hypophysectomy in rats is accompanied by a significant rise in PNPase activity in ribosomal fractions of the liver. Injection of growth hormone into operated animals produces inhibition of PNPase activity. The linear dependence "dose-response" was recorded with the use of a dosage range of 5 to 100 micrograms/animal. The action of growth hormone was most pronounced 18 hours following its single injection.
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D013006:Growth Hormone / Q000502:physiology*; D007016:Hypophysectomy; D008099:Liver / Q000201:enzymology*; D011117:Polyribonucleotide Nucleotidyltransferase / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
chemical_list: D013006:Growth Hormone; D011117:Polyribonucleotide Nucleotidyltransferase
vernacular_title: Znachenie gormona rosta v reguliatsii aktivnosti polinukleotidfosforilazy v pecheni krys.