[Ulcer of the esophagus after intake of emeproniumbromide (author's transl)].
Two female patients were treated because of pollakiuria with emeproniumbromide tablets. They developed extended ulcers of the esophageal mucosa. The tablets had been taken late in the evening with only little fluid. Ulcer formation is thought to be due to prolonged passage time and to a locally damaging effect of the hygroscopic compound. There may be lesions of the esophageal musculature as well, as demonstrated by considerable disturbance of esophageal motility. Ulcers tend to be painfull; they heel fast without formation of scars.
D000328:Adult; D004629:Emepronium / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004935:Esophageal Diseases / Q000139:chemically induced*; D005260:Female; D006801:Humans; D010528:Peristalsis / Q000187:drug effects; D011141:Polyuria / Q000188:drug therapy; D000644:Quaternary Ammonium Compounds / Q000009:adverse effects*; D013607:Tablets; D014456:Ulcer / Q000139:chemically induced*
D000644:Quaternary Ammonium Compounds; D013607:Tablets; D004629:Emepronium
Osophagusulkus nach Einnahme von Emeproniumbromid.