title: [Pharmacokinetics and tolerance of Cefazedone compared with Cefazoline (author's transl)].
abstract: In a randomized cross over study Cefazoline and Cefazedone were administered i.v. as injection of 2 minutes duration and as infusion of 30 minutes duration. The concentrations in blood plasma and the excretion with the urine were similar for both substances and differed only with regard to their levels during the first 60 minutes, depending on the mode of administration.
mesh_terms: D002437:Cefazolin / Q000097:blood / Q000378:metabolism / Q000652:urine / Q000031:analogs & derivatives; D002511:Cephalosporins / Q000097:blood / Q000378:metabolism* / Q000652:urine; D004361:Drug Tolerance; D006801:Humans; D008297:Male
chemical_list: D002511:Cephalosporins; C021341:cefazedone; D002437:Cefazolin
vernacular_title: Pharmakokinetik und Verträglichkeit von Cefazedon im Vergleich zu Cefazolin.