title: High-performance liquid chromatographic analysis of trimethoprim and sulfamethoxazole in dosage forms.
abstract: A rapid, sensitive, and automatable high-performance liquid chromatographic method is presented for the determination of sulfamethoxazole, trimethoprim, and a preservative in dosage forms in the presence of excipients and degradation products.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D008722:Methods; D013420:Sulfamethoxazole / Q000032:analysis*; D013535:Suspensions / Q000032:analysis; D013607:Tablets / Q000032:analysis; D014295:Trimethoprim / Q000032:analysis*
chemical_list: D004338:Drug Combinations; D013535:Suspensions; D013607:Tablets; D014295:Trimethoprim; D013420:Sulfamethoxazole