Abnormalities of the pupil and visual-evoked potential in quinine amblyopia.
Total blindness with a transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials developed in a 54-year-old man after the use of quinine sulfate for leg cramps. He later recovered normal visual acuity. A transient tonic pupillary response, denervation supersensitivity, and abnormal visual-evoked potentials in quinine toxicity, to our knowledge, have not been previously reported.
D001766:Blindness / Q000139:chemically induced* / Q000503:physiopathology; D003714:Denervation; D005071:Evoked Potentials; D006801:Humans; D007498:Iris / Q000294:innervation; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000188:drug therapy; D010775:Photic Stimulation; D011680:Pupil; D011803:Quinine / Q000009:adverse effects* / Q000627:therapeutic use; D012075:Remission, Spontaneous; D014794:Visual Fields
D011803:Quinine