title: [Malignant histiocytosis with cutaneous involvement: enzymecytochemical and immunocytological studies (author's transl)].
abstract: Malignant histiocytosis with cutaneous involvement occurred in a 27-year-old man. There were generalized weakness, abdominal pain, lymphadenopathy, fever and firm, papulonodular cutaneous infiltrations. The tumour cells were identified as malignant histiocytes by specially adapted enzyme-cytochemical and immunocytological methods on cryostat sections and single-cell suspension from the cutaneous infiltrates. The malignant histiocytes are characterized by diffuse activity of esterases and acid phosphatase. In addition, tests in single-cell suspension make it possible to differentiate the cells further according to cytomorphological and enzyme-cytochemical criteria.
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D004950:Esterases / Q000032:analysis; D006644:Histiocytes / Q000201:enzymology; D006801:Humans; D008206:Lymphatic Diseases / Q000201:enzymology / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000201:enzymology / Q000473:pathology*
chemical_list: D004950:Esterases; D000135:Acid Phosphatase
vernacular_title: Maligne Histiozytose mit Hautmanifestationen. Enzymzytochemische und immunzytologische Untersuchungen.