[Effect of rations with a varying phospholipid content on rat liver phosphorylase A1 and A2 and cholesterol esterase activity].
The effect of varied amounts of phospholipids in the diet (100, 30 and 0.5% of the total lipid content) on the lipid composition and activity of lysosomal phospholipases A1 and A2 and cholesterinesterase of the rat liver was studied. The experiment lasted 24 days. The liver weight increased in both groups of animals under test, no differences in the content of total lipids being found. Variations in the activity of lipolytic enzymes were of different directions. The animals given pure phospholipids demonstrated less activity of phospholipase A1 without changes in phospholipase A2 activity, a tendency towards elevated activity of cholesterinesterase and drop in the content of phospholipids in the liver. The animals fed 30% of phospholipids showed higher activity of phospholipases A1 and A2, reduced activity of cholesterinesterase as well as decreased protein content in the liver.
D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D004032:Diet; D004789:Enzyme Activation / Q000187:drug effects; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D010740:Phospholipases / Q000378:metabolism*; D010741:Phospholipases A / Q000378:metabolism*; D054466:Phospholipases A1; D054467:Phospholipases A2; D010743:Phospholipids / Q000008:administration & dosage*; D051381:Rats; D002787:Sterol Esterase / Q000378:metabolism*
D010743:Phospholipids; D010740:Phospholipases; D002265:Carboxylic Ester Hydrolases; D002787:Sterol Esterase; D010741:Phospholipases A; D054466:Phospholipases A1; D054467:Phospholipases A2
Vliianie ratsionov s razlichnym soderzhaniem fosfolipidov na aktivnost' fosfolipaz A1 i A2 i kholesterinésterazy pecheni krys.