Cholangitis in a child due to biliary tract anomalies.
A 29-month-old child with persistent cholangitis and steatorrhea complicating congenital hepatic fibrosis underwent radiographic evaluation of the biliary tree. Communicating intrahepatic cavernous ectasias were demonstrated by percutaneous transhepatic cholangiography, a procedure deemed safe in children of this age group. Unlike most patients with cholangitis, he had documented steatorrhea and growth failure which resolved following successful treatment with trimethoprim-sulfamethoxazole. Bacteriologic diagnosis was made by direct culture of liver tissue combined with duodenal intubation.
D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities* / Q000000981:diagnostic imaging; D002446:Celiac Disease / Q000209:etiology; D002675:Child, Preschool; D002761:Cholangitis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000209:etiology; D008107:Liver Diseases / Q000151:congenital*; D008297:Male; D011859:Radiography; D013420:Sulfamethoxazole / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use
D014295:Trimethoprim; D013420:Sulfamethoxazole