Effect of lipid soluble antioxidants on cytotoxicity induced by photochemical products of cholesterol.
Lipid soluble antioxidants, butylated hydroxytoluene and vitamin E, were shown to suppress cytotoxicity induced by cholesterol-derived photoproducts in Chinese hamster embryo cells. These cholesterol-derived photoproducts were rather toxic.
D000818:Animals; D000975:Antioxidants; D002084:Butylated Hydroxytoluene / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000494:pharmacology; D006224:Cricetinae; D003412:Cricetulus; D004622:Embryo, Mammalian; D010777:Photochemistry; D014810:Vitamin E / Q000494:pharmacology*
D000975:Antioxidants; D014810:Vitamin E; D002084:Butylated Hydroxytoluene; D002784:Cholesterol