[Effect of theophylline-ethylenediamine in obstructive lung disease (author's transl)].
In 12 patients with obstructive respiratory tract disease there occurred a decrease in the mean respiratory tract resistance of maximally 37% and a fall in pulmonary artery pressure of maximally 28% six hours after oral administration of 700 mg theophylline-ethylenediamine (Aminophyllin retard). The effect lasted beyond the 12 hours of observation on the first day and, after 14-day administration of twice daily 350 mg, remained nearly unchanged. After two weeks there was a clinically significant increase in vital capacity averaging 13%, the residual volume decreased by 14%.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000403:Airway Resistance; D001249:Asthma / Q000188:drug therapy*; D001794:Blood Pressure; D001991:Bronchitis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery; D012115:Residual Volume; D013806:Theophylline / Q000627:therapeutic use*; D013997:Time Factors
D013806:Theophylline
Wirkung von Theophyllin-Aethylendiamin bei obstruktiven Atemwegserkrankungen.