title: Stiff-man syndrome with abnormalities in CSF and computerized tomography findings. Report of a case.
abstract: We report a case of stiff-man syndrome with abnormal spinal fluid. Serum protein values were normal, but the spinal fluid levels of immunogammaglobulin G and acute-phase proteins were elevated. We discuss the possibility of an inflammatory process of the nervous system as a cause for these findings. Another interesting observation in our patient was that of local atrophies seen on computerized tomography, indicating hemispheral and especially brainstem lesions. Furthermore, as a new therapeutic possibility, we demonstrated the improvement of spasms and rigidity under the influence of heat.
mesh_terms: D001284:Atrophy; D002556:Cerebrospinal Fluid Proteins / Q000378:metabolism; D003975:Diazepam / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008875:Middle Aged; D009127:Muscle Rigidity / Q000134:cerebrospinal fluid* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G; D003975:Diazepam