Barr bodies in testis with Klinefelter syndrome.
Barr bodies are described in the interstitial cells of testes of a chromatin-positive patient with Klinefelter syndrome. Ultrastructural studies confirm the origin of the Barr body from the nuclear chromatin. Ultrastructurally the interstitial cells showed diminished, smooth endoplasmic reticulum and lipid droplets probably indicating impaired function.
D000328:Adult; D006801:Humans; D007713:Klinefelter Syndrome / Q000235:genetics*; D008297:Male; D012728:Sex Chromatin / Q000032:analysis*; D013737:Testis / Q000648:ultrastructure*