[Capacitive vascular reactions of the skeletal musculature before and after adrenoreceptor blockade].
In acute experiments on cats under autoperfusion of the denervated shank vessels with a constant blood volume, injection of noradrenaline into the perfusate could either decrease or increase vascular capacitance. The character and magnitude of reaction depended on the initial level of venous pressure: in pressure 10--15 Hg the decrease was predominant, whereas in pressure 0 and 25 mm Hg--the increase of vascular capacitance occurred. Under blockade of beta-adrenoreceptors with propranolol the dependence of the character of changes in shank vessels capacitance remained the same. Under dihydroergotoxin blockade of alpha-adrenoreceptors, noradrenaline produced only an insignificant increase of the vascular capacitance.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004088:Dihydroergotoxine / Q000494:pharmacology; D006614:Hindlimb / Q000098:blood supply / Q000294:innervation; D009132:Muscles / Q000098:blood supply*; D009638:Norepinephrine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects; D014680:Veins / Q000187:drug effects
D011941:Receptors, Adrenergic; D004088:Dihydroergotoxine; D011433:Propranolol; D009638:Norepinephrine
Reaktsii emkostnykh sosudov skeletnoĭ muskulatury do i posle blokady adrenoretseptorov.