title: Anaplastic giant and spindle-cell carcinoma of the thyroid: a different therapeutic approach.
abstract: The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multisciplinary approach to treatment of this aggressive cancer is more effective than a single-treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irraditation, and chemotherapy is described in this case report. The preliminary result is encouraging.
mesh_terms: D001500:BCG Vaccine / Q000627:therapeutic use; D002277:Carcinoma / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000628:therapy*
chemical_list: D001500:BCG Vaccine