Cryolesions of bone. An experimental study. part I: Examinations in technique of controlled cryolesion on bone.
Three different approaches of freezing rabbit tibia bones are demonstrated. Intramedullary freezing seems to be the safest method to avoid soft tissue necrosis. Bone specimens removed immediately after the freezing-thawing process showed electron optically evidence of irreversible damage of bone cells in all cases.
D000818:Animals; D001842:Bone and Bones / Q000293:injuries* / Q000648:ultrastructure; D003452:Cryosurgery / Q000009:adverse effects*; D005615:Freezing; D006253:Haversian System / Q000648:ultrastructure; D011817:Rabbits; D013977:Tibia / Q000293:injuries*