Influenza B virus: alpha-amanitin sensitivity of replication and primer-dependence of in vitro transcription.
The replication of influenza B/Lee/40 virus in MDCK (canine kidney) cells was sensitive to alpha-amanitin and actinomycin D. In vitro, virion transcriptase activity was stimulated by dinucleotide primers such as ApG. The above characteristics are shared by A/WSN virus.
D000546:Amanitins / Q000494:pharmacology*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D003609:Dactinomycin / Q000494:pharmacology; D009980:Influenza A virus / Q000201:enzymology; D009711:Nucleotides / Q000494:pharmacology; D009975:Orthomyxoviridae / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development
D000546:Amanitins; D009711:Nucleotides; D003609:Dactinomycin; D012321:DNA-Directed RNA Polymerases