title: [Malignant hyperthermia. A case report (author's transl)].
abstract: An exceptionally serious case of malignant hyperthermia in a 17 year old male is presented. A detailed description of the case is given concerning symptomatology, course, laboratory data and morphologic alterations. Our patient died after 7 weeks of intensive care due to therapy resistant septicemia and coagulation disorder. Intense adynamia and advanced muscular atrophy were present. Necropsy showed regionally different extensive lysis of skeletal muscles. In the discussion the advantage of an "ice gravel" producing machine in cooling measures, the necessity of higher procaine doses and problems of long term therapy in trauma patients coincidentally affected with malignant hyperthermia, are stressed.
mesh_terms: D000293:Adolescent; D006221:Halothane / Q000009:adverse effects; D006323:Heart Arrest / Q000628:therapy; D006474:Hemorrhagic Disorders / Q000150:complications; D006801:Humans; D007053:Ice; D008297:Male; D008305:Malignant Hyperthermia / Q000150:complications / Q000473:pathology*; D009133:Muscular Atrophy / Q000209:etiology; D011343:Procaine / Q000627:therapeutic use; D012151:Resuscitation; D018805:Sepsis / Q000150:complications; D013390:Succinylcholine / Q000009:adverse effects
chemical_list: D007053:Ice; D011343:Procaine; D013390:Succinylcholine; D006221:Halothane
vernacular_title: Maligne Hyperthermie. Ein Fallbericht.