Failure to visualize adrenal glands in a patient with bilateral adrenal hyperplasia.
A patient with clinical and biochemical evidence of Cushing's disease and severe hyperlipidemia underwent an adrenal imaging procedure with NP-59 (6 beta-[131I]iodomethyl-19-norcholesterol), without visualization of either gland. Correction of the hyperlipidemia followed by repeated adrenal imaging resulted in bilateral visualization. A pituitary tumor was removed at surgery, confirming the diagnosis of Cushing's disease.
D000301:Adosterol; D000311:Adrenal Glands / Q000000981:diagnostic imaging* / Q000473:pathology; D003480:Cushing Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D006965:Hyperplasia; D007457:Iodine Radioisotopes; D008875:Middle Aged; D011877:Radionuclide Imaging; D013261:Sterols
D007457:Iodine Radioisotopes; D013261:Sterols; D000301:Adosterol