title: Morbidity associated with anomalous origin of the right coronary artery from the left sinus of Valsalva.
abstract: Anomalies of the coronary arteries occur infrequently, but can have major clinical consequences. Many reports have described an association between sudden death and origin of the left coronary artery from the right sinus of Valsalva, but origin of the right coronary artery from the left sinus of Valsalva is thought to be benign. Herein, we describe a patient in whom anomalous origin of the right coronary artery from the left sinus of Valsalva was associated with significant cardiovascular morbidity. A 25-year-old man developed complete heart block and myocardial infarction in the distribution of a dominant anomalous right coronary artery free of atherosclerotic lesions. Systolic compression at the origin of the anomalous artery was demonstrated. The left coronary artery was normal. We conclude that anomalous origin of the right coronary artery from the left sinus of Valsalva may be associated with significant cardiovascular morbidity in the absence of atherosclerosis.
mesh_terms: D000328:Adult; D001161:Arteriosclerosis / Q000150:complications; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003327:Coronary Disease / Q000453:epidemiology*; D003330:Coronary Vessel Anomalies; D003645:Death, Sudden / Q000209:etiology; D004562:Electrocardiography; D006327:Heart Block / Q000150:complications; D006801:Humans; D007484:Iowa; D009203:Myocardial Infarction / Q000150:complications; D012850:Sinus of Valsalva / Q000002:abnormalities*