[Influence of manganese on the level of glycogen and its fractions in organism tissues].
Changes in the level of total glycogen and its fractions in the organism tissues were studied under conditions of injecting different doses of manganese into intact rabbits. It is established that the trace element doses of 0.6 and 3 mg per 1 kg of the weight cause a significant increase in the total glycogen quantity in the liver, mainly due to its free and protein-bound forms. Higher doses of manganese (6 mg/kg) produce an opposite effect. In the cerebral tissues the level increase of total glycogen and in most cases of its fractions occurs under the influence of the trace element in doses of 0.1-6 mg/kg. In the myocardium tissue manganese did not cause any significant changes in the glycogen level. It is supposed that manganese participates in the processes of glycogene metabolism in the organism.
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006003:Glycogen / Q000378:metabolism*; D006321:Heart / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008112:Liver Glycogen / Q000378:metabolism*; D008297:Male; D008345:Manganese / Q000494:pharmacology*; D009206:Myocardium / Q000378:metabolism*; D009928:Organ Specificity; D011817:Rabbits
D008112:Liver Glycogen; D008345:Manganese; D006003:Glycogen
Vliianie margantsa na uroven' glikogena i ego fraktsii v tkaniakh organizma.