title: Apical distribution of fatty acid esterification capacity along the villus-crypt unit of rat jejunum.
abstract: Distribution of fatty acid esterification capacity along the structure of the villus-crypt unit was studied in both in vivo perfused an in vitro incubated rat jejunum. Using a cryostat sectioning technique, the intestine was sectioned transversely at 6 micron thickness, from the tip of the villus to the crypt. Morphology and sucrase activity were used as markers to define the location along the villus-crypt unit. Fatty acid esterification capacity was found to be more apically concentrated in both in vivo and in vitro preparations. The apical distribution of fatty acid esterification capacity is a reflection of the distribution patterns of lipid esterifying enzyme activity along the villus-crypt units.
mesh_terms: D051103:1-Acylglycerol-3-Phosphate O-Acyltransferase; D000217:Acyltransferases / Q000378:metabolism; D000818:Animals; D003066:Coenzyme A Ligases / Q000378:metabolism; D004951:Esterification; D005227:Fatty Acids / Q000378:metabolism*; D005994:Glycerophosphates / Q000378:metabolism; D007583:Jejunum / Q000033:anatomy & histology / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D051381:Rats; D013393:Sucrase / Q000378:metabolism
chemical_list: D005227:Fatty Acids; D005994:Glycerophosphates; D000217:Acyltransferases; D051103:1-Acylglycerol-3-Phosphate O-Acyltransferase; D013393:Sucrase; D003066:Coenzyme A Ligases