Mesangial proliferative glomerulonephritis in mixed connective tissue disease (MCTD).
A patient who had clinical and serologic evidence for Mixed Connective Tissue Disease (MCTD) developed mesangial proliferative glomerulonephritis with demonstrable immune complexes. Most cases of MCTD with a renal lesion have exhibited membranous glomerular lesions. Since the prevalence of renal involvement in MCTD has ranged from 5-20%, it is possible that too few cases have been studied to describe fully the range of renal lesions seen in this disease entity.
D000328:Adult; D000936:Antigen-Antibody Complex; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008947:Mixed Connective Tissue Disease / Q000150:complications*
D000936:Antigen-Antibody Complex