title: [Preliminary clinical and experimental data on a new anti-arrhythmic drug: lorcainide].
abstract: A first series of personal results in the treatment of arrhythmia with lorcainide is presented. Findings were obtained by recording for 24 hr with Holter and compared with those observed in patients treated with quinidine. An ECG study was also made of the atrial and nodal refractory periods. The conclusion is drawn that lorcainaide possesses an undoubted and protracted anti-arrhythmic effect, and does not exert a significant influence on refractory period values.
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D044482:Benzeneacetamides; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use*
chemical_list: D000889:Anti-Arrhythmia Agents; D044482:Benzeneacetamides; D010880:Piperidines; C015970:lorcainide
vernacular_title: Primi rilievi clinici e sperimentali su un nuovo antiaritmico: la lorcainide.