[Effect of low-molecular peptides from the blood of burned dogs on the functional state of intact liver mitochondria in mice].
In presence of toxic low molecular peptides, isolated from blood of dogs with burns within 3-4 hrs after the injury, the following phenomena were observed in intact mouse liver mitochondria: decrease in calcium-accumulating ability of mitochondria, sheir irreversible swelling, decrease in the rate of oxygen utilization, decrease in coefficients of stimulation of respiration and of respiratory control, decrease in the rates of phosphorylation and of oxidative phosphorylation.
D000818:Animals; D002056:Burns / Q000097:blood*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D051379:Mice; D008930:Mitochondria, Liver / Q000187:drug effects*; D008933:Mitochondrial Swelling / Q000187:drug effects; D008970:Molecular Weight; D010101:Oxygen Consumption / Q000187:drug effects; D010455:Peptides / Q000097:blood / Q000633:toxicity*
D010455:Peptides
Vliianie nizkomolekuliarnykh peptidoz iz krovi obozhzhennykh sobak na funktsional'noe sostoianie intaktnykh mitokhondriĭ pecheni mysheĭ.