title: Fine structure of the lumbosacral neural folds in the mouse embryo.
abstract: The neural folds in the lumbosacral region of the normal 8-day and 9-day mouse embryo were studied by means of transmission electron microscopy with and without lanthanum treatment. The cells showed an abundance of ribosomes, microtubules arranged parallel to the long axes of the cells, and microfilaments extending across the apices. At the luminal border junctional complexes were common, and an occasional midbody was seen stretching between adjacent cells nearing the end of telophase. In the 8-day embryos, gap junctional vesicles (annular nexuses) bounded by layered membranes and containing cytoplasm with ribosome-like material were commonly observed; at 9 days the vesicles were relatively rare. The lanthanum-treated material demonstrated that the tracer was able to pass through the subluminal junctional complexes and throughout the intercellular spaces. However, the space between the membranes of the gap junctional vesicles lacked lanthanum and thus apparently did not communicate with the intercellular space.
mesh_terms: D000818:Animals; D007365:Intercellular Junctions / Q000648:ultrastructure; D008161:Lumbosacral Region; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D008938:Mitosis; D013116:Spinal Cord / Q000196:embryology* / Q000648:ultrastructure