[Relative concentration of VLDL C-apolipoproteins in the hyperlipoproteinaemia of haemodialysis-treated chronic renal failure (author's transl)].
The hypertriglyceridaemia of patients with haemodialysis-treated chronic renal insufficiency was characterized in respect of the apolipoproteins C of VLDL. Using Kane's method, particular attention was paid to the CII/CIII ratio of VLDL isolated by ultracentrifugation in eleven hemodialyzed patients with hypertriglyceridaemia. There was a significant decrease of this ratio compared to twenty three patients with essential hypertriglyceridaemia. A removal defect is suggested as fundamental to the pathogenesis of the hypertriglyceridaemia of renal failure since apoprotein CII acts as a specific activator of lipoprotein lipase.
D006801:Humans; D006953:Hyperlipoproteinemia Type IV / Q000097:blood; D006951:Hyperlipoproteinemias / Q000097:blood* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications; D008079:Lipoproteins, VLDL / Q000097:blood*; D006435:Renal Dialysis
D008079:Lipoproteins, VLDL
Concentrations relatives des apolipoprotéines C dans les VLDL circulantes au cours des hyperlipoprotéinémies de l'insuffisance rénale chronique traitée par hémodialyse itérative.