Neonatal herpes simplex virus infection introduced by fetal-monitor scalp electrodes.
An infant was severely infected with herpes simplex virus as a result of fetal monitoring with scalp electrodes on the buttocks. The first vesicles appeared at the site where the electrodes had been placed and, by day 9 after birth, additional lesions covered the entire perineum and lower extremities. The child developed acute meningoencephalitis and pneumatosis intestinalis. Herpes simplex virus was isolated from cultures of skin vesicle fluid, cornea, saliva, blood, and spinal fluid. The infection resolved after treatment with adenosine arabinoside, administered intravenously for 11 days and applied topically for another 15 days. A follow-up examination when the child was 2 years old disclosed no physical or neurologic abnormalities. This case illustrates the risk of introducing herpes simplex infection by internal fetal monitoring.
D004566:Electrodes; D005323:Fetal Monitoring / Q000295:instrumentation; D006561:Herpes Simplex / Q000151:congenital* / Q000188:drug therapy / Q000635:transmission; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008590:Meningoencephalitis / Q000209:etiology*; D011006:Pneumatosis Cystoides Intestinalis / Q000209:etiology*; D014740:Vidarabine / Q000627:therapeutic use
D014740:Vidarabine