A survey of reducing agents for the synthesis of tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) from [99Tc] pertechnetate in aqueous solution.
We have studied the effectiveness of various reducing agents in the production of the well-characterized complex [99TcO(SCH2CH2S)2]- from pertechnetate in aqueous solution. The reductants tested included sodium dithionite, hypophosphorous acid, formamidine sulfinic acid, dithiothreitol, hydrazine, and hydroxylamine. Of these, only sodium dithionite in the pH range 11--13 was found to give quantitative yields of the required technetium complex.
D001152:Arsenicals; D004227:Dithionite; D004229:Dithiothreitol; D006834:Hydrazines; D006863:Hydrogen-Ion Concentration; D006898:Hydroxylamines; D015609:Organotechnetium Compounds; D010084:Oxidation-Reduction; D013441:Sulfinic Acids; D013667:Technetium
D001152:Arsenicals; D006834:Hydrazines; D006898:Hydroxylamines; D015609:Organotechnetium Compounds; D013441:Sulfinic Acids; D004227:Dithionite; C024228:tetraphenylarsonium oxotechnetiumbis(ethanedithiolate); D013667:Technetium; D004229:Dithiothreitol