Intestinal metabolism of DNOC and DNBP in the rat.
The metabolism of the dinitrophenols DNOC and DNBP and their respective monoamino derivatives, 6-ANOC and 6-ANBP, was studied in rat caecal incubates. All of the compounds were reduced to their corresponding diamino metabolites. The results are discussed in relation to the comparative toxicology of the dinitrophenols with special regard to a possible significance of the intestinal metabolites.
D000818:Animals; D002432:Cecum / Q000378:metabolism; D004140:Dinitrophenols / Q000378:metabolism*; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D008297:Male; D051381:Rats; D013053:Spectrophotometry
D004140:Dinitrophenols