title: Immobilization and characterization of L-asparaginase on hollow fibers.
abstract: L-Asparaginase was immobilized with various methods: cyanogen bromide, cyanuric chloride and cross-linking with glutaraldehyde. A dialysis device was  transformed in a bioreactor with the enzyme immobilized on the outer surface of hollow fibers. Results on kinetic behavior, stability in storage and lyophilization are reported.
mesh_terms: D001215:Asparaginase; D001639:Bicarbonates; D002254:Carbonates; D002482:Cellulose; D003488:Cyanogen Bromide; D003956:Dialysis / Q000295:instrumentation*; D004800:Enzymes, Immobilized; D007700:Kinetics; D006435:Renal Dialysis
chemical_list: D001639:Bicarbonates; D002254:Carbonates; D004800:Enzymes, Immobilized; D002482:Cellulose; D001215:Asparaginase; D003488:Cyanogen Bromide