title: GPT polymorphism in the population of Bologna and linkage analysis with beta-thalassaemia.
abstract: GPT polymorphism was studied in 500 voluntary blood donors from the Bologna population. The following phenotype frequencies were obtained: GPT 1 = 29.60%, GPT 1-2 = 49.80% and GPT 2 = 20.60%. The frequencies of the alleles were: GPT1 - 0.545 and GPT2 = 0.455. Analysis of 24 informative families has excluded linkage between GPT and beta-thalassaemia.
mesh_terms: D000410:Alanine Transaminase / Q000235:genetics*; D000483:Alleles; D005787:Gene Frequency; D008040:Genetic Linkage; D006801:Humans; D007558:Italy; D010641:Phenotype; D011110:Polymorphism, Genetic; D013789:Thalassemia / Q000201:enzymology* / Q000235:genetics
chemical_list: D000410:Alanine Transaminase