Leg scanning with radioisotope-labeled fibrinogen in patients undergoing hip surgery. Comparison with contrast phlebography and lung scans.
To establish whether radioisotope-labeled fibrinogen leg scanning is of value in the context of hip surgery, we prospectively studied 21 consecutive patients undergoing either total hip replacement (14) or open repair of a hip fracture (seven) with leg scans, contrast phlebography, and ventilation and perfusion lung scans. We found that in eight patients (38%), venous thromboembolism developed postoperatively. Agreement between phlebographic and leg scanning results was excellent. In no patient was venous thrombosis limited to the thigh on the operated-on side, a vital consideration in application of fibrinogen leg scanning to this patient population. Two patients had lung scan changes indicative of embolism; both had thrombi extending into thigh veins. Leg scanning with radioisotope-labeled fibrinogen appears to be a useful method for monitoring patients undergoing hip surgery, if the upper three counting points on the operated-on side are excluded.
D000328:Adult; D000368:Aged; D005260:Female; D005340:Fibrinogen; D006622:Hip Prosthesis; D006801:Humans; D007866:Leg / Q000000981:diagnostic imaging*; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010690:Phlebography / Q000379:methods*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013923:Thromboembolism / Q000517:prevention & control*
D011868:Radioisotopes; D005340:Fibrinogen