title: [Duration of preoxygenation in patients with normal and impaired lung function (author's transl)].
abstract: We determined the time required for the O2-filling of the lung, which is important for reasons of preoxygenation prior to intubation during apnoea and apnoeic oxygenation. 97 patients were examined. A multiple breath nitrogen washout method, the Hewlett-Packard lung function analyser HP 47402 A, was used. Complete O2-saturation of the lung in three different groups of patients took a mean time of 2 min 55 s, 4 min 20 s and 7 min 17 s. The differences were attributed to varying qualities of ventilatory gas distribution. Total O2-filling of the lung is necessary for apnoeic oxygenation. After breathing air, there is a mean decrease of PaO2 from 97 to 54 mm of mercury in 2 min of apnoea. For purposes of intubation, a 90% O2-filling of the lung takes not more than 1 and a half minutes even in patients with seriously impaired lung function. The gain of apnoeic tolerance time is approximately 4 min.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001049:Apnea / Q000503:physiopathology; D002648:Child; D005260:Female; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism; D010101:Oxygen Consumption
chemical_list: D009584:Nitrogen
vernacular_title: Dauer der Praeoxygenation bei Patienten mit regelrechter und gestörter Lungenfunktion.