title: Nervous control of migratory myoelectric complex of the small bowel.
abstract: The effects on the migratory myoelectric complex (MMC) of transplantation of small bowel loops were investigated in miniature swine with chronically implanted bipolar electrodes. Four experimental models (A--D) were studied. In groups A and B, jejunal loops were either interchanged in sequence or transplanted to the ileum with preservation of intact neurovascular pedicles. In groups C and D, bowel segments were totally isolated and replanted in situ (group C) or as modified Thiry-Vella loops (group D). Weekly records of fasting myoelectrical activity were then taken. Group A and B animals showed reintegration of the transplanted bowel segments into a normal MMC sequence after a remodeling period. The replanted bowel segments of groups C and D displayed MMCs throughout the study period. The in situ replanted segments of group C were reintegrated into the normal sequence after a delay of 3--4 wk. These results indicate that the organization of the MMC is not solely determined by the extrinsic nervous system.
mesh_terms: D000200:Action Potentials; D000818:Animals; D005260:Female; D007421:Intestine, Small / Q000294:innervation / Q000502:physiology* / Q000637:transplantation; D009119:Muscle Contraction; D009121:Muscle Denervation; D009130:Muscle, Smooth / Q000502:physiology; D013552:Swine; D014182:Transplantation, Autologous