[Damaging action of lincomycins on the intestines of experimental animals].
It was found that lincomycin and 7-chlor-7-desoxylincomycin administered 3 times induced severe enterocolitis accompanied by dysbacteriosis in a part of the experimental rabbits, while no such phenomenon was observed in the mice. Treatment of the animals with neomycin for 10 days protected them from death of severe forms of enterocolitis.
D000818:Animals; D003092:Colitis / Q000139:chemically induced / Q000473:pathology; D004751:Enteritis / Q000139:chemically induced / Q000473:pathology; D007422:Intestines / Q000187:drug effects* / Q000382:microbiology / Q000473:pathology; D008034:Lincomycin / Q000009:adverse effects* / Q000031:analogs & derivatives; D051379:Mice; D011817:Rabbits; D013997:Time Factors
D008034:Lincomycin
Povrezhdaiushchee deĭstvie linkomitsinov na kishechnik éksperimental'-nykh zhivotnykh.