[Mechanism of the change in electrolyte and carbohydrate metabolism in the submandibular salivary gland in experimental botulism in rats].
Content of lactic and pyruvic acids, glycogen, sodium and potassium ions are well as the total LDH activity and its isoenzyme spectrum were not distinctly altered, when secretion of salivary glands was inhibited by administration of botulinic toxin into rats (within 48 hrs after the toxin treatment). But within 14 days the following alterations were observed in the impaired salivary glands: decrease in content of glycogen and potassium, increase in concentration of lactic and pyruvic acids, elevation in total LDH activity and change in its isoenzyme spectrum (increase in content of the fractions responsible for regulation of anaerobic metabolism).
D000818:Animals; D001906:Botulism / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D004789:Enzyme Activation; D005260:Female; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D012964:Sodium / Q000378:metabolism*; D013363:Submandibular Gland / Q000294:innervation / Q000378:metabolism*
D007527:Isoenzymes; D012964:Sodium; D007770:L-Lactate Dehydrogenase; D011188:Potassium
K mekhanizmu izmeneniia élektrolitnogo i uglevodnogo obmena v podcheliustnoĭ sliunnoĭ zheleze pri éksperimental'nom botulizme u krys.