A criterion for the establishment of a stable polymorphism of higher order with an application to the evolution of polymorphism.
This note gives some further useful properties of the constant fitness selection model for multiple alleles which pertain to the effects of adding a new allele to n preexisting alleles in stable equilibrium. In particular the conditions are derived for the establishment of a stable equilibrium involving all n + 1 alleles. For 3 alleles (i.e. n = 2) I give a complete qualitative solution, including the case of the replacement of one diallelic polymorphism by another. As an application I discuss a possible mechanism for the evolution of polymorphism using Monte Carlo methods similar to Lewontin, Ginzburg and Tuljapurkar (1978).
D000483:Alleles; D008957:Models, Genetic; D009010:Monte Carlo Method; D009154:Mutation; D011110:Polymorphism, Genetic