Testing for Hardy-Weinberg equilibrium.
The class of admissible tests for Hardy-Weinberg equilibrium in a multi-allelic system is characterized. The standard goodness-of-fit chi-square tests is shown to be admissible for systems of two or more alleles. The conditional probability distribution required to determine the exact significance level of this test is presented.
D000483:Alleles; D000818:Animals; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D008957:Models, Genetic; D011336:Probability