Clot retraction in a factor XIII free system.
The role of Factor XIII in clot retraction was studied using the plasma from Factor XIII-deficient patients. Time course experiments revealed no significant difference in clot retraction between a plasma deficient in Factor XIII and one to which purified Factor XIII had been added. Using Factor XIII-free fibrinogen and Factor XIII-deficient platelets, it is shown that there is no significant difference in clot retraction with or without added Factor XIII.
D003018:Clot Retraction; D004591:Electrophoresis, Polyacrylamide Gel; D005176:Factor XIII / Q000302:isolation & purification / Q000502:physiology*; D005177:Factor XIII Deficiency / Q000097:blood; D005337:Fibrin / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D010976:Platelet Count; D013917:Thrombin / Q000032:analysis
D005337:Fibrin; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin