Familial renal cystic dysplasia associated with maternal diabetes mellitus.
Two of eight children born to unrelated parents were found to have cystic renal dysplasia, but no other malformations. A third sibling was presumed to have similar renal disease based upon typical clinical and radiographic findings. In addition to possible genetic causes, maternal diabetes mellitus is suggested as a potential etiologic factor.
D000328:Adult; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007690:Polycystic Kidney Diseases / Q000235:genetics*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications*