title: Molecular structure influencing either a sweet or bitter taste among aldoximes.
abstract: A series of cyclohexylaldoximes was examined for their sweet or bitter taste using discriminant analysis. The structures of the molecules were described using molecular connectivity. A two-variable linear discriminant function and critical value were computed that correctly assigned 17 of the 20 molecules to their observed sweet or bitter taste categories. The same discriminant function can predict correctly the taste categories of seven of eight additional molecules.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D008433:Mathematics; D010091:Oximes; D013329:Structure-Activity Relationship; D013549:Sweetening Agents; D013649:Taste
chemical_list: D010091:Oximes; D013549:Sweetening Agents