Successful treatment of keratoacanthoma with intralesional fluorouracil.
Forty-one keratoacanthomas (KA) occurring in thirty patients were treated with weekly intralesional injections of 5-fluorouracil (5-FU). Forty lesions cleared after an average of three injections in an average of 3.4 weeks (range, 2 to 6 weeks). This response suggests that intralesional injections of 5-FU are the treatment of choice for KAs.
D000328:Adult; D000368:Aged; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007271:Injections, Intradermal; D007636:Keratoacanthoma / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D005472:Fluorouracil