Persistent rubella-specific IgM-antibody in the cerebrospinal fluid of a child with congenital rubella.
Rubella-specific IgM-antibody was detected, using a solid-phase radioimmunoassay (RIA) method, in the CSF of a child with congenital rubella at ages 3 and 4 years. No rubella-specific Igm was found in the CSF of 20 other children with congenital rubella, and the ratios of rubella-specific IgG RIA antibody titres in serum and CSF were normal.
D000914:Antibodies, Viral / Q000134:cerebrospinal fluid*; D000918:Antibody Specificity; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007075:Immunoglobulin M / Q000134:cerebrospinal fluid*; D011863:Radioimmunoassay; D012409:Rubella / Q000151:congenital* / Q000276:immunology
D000914:Antibodies, Viral; D007075:Immunoglobulin M