title: [Malignant hyperthermia. I. Observations in connection with its pathogenesis and course (author's transl)].
abstract: Malignant hyperthermia developed in the 94th minute of anesthesia undergone by a nearly 5-year-old girl. Two minutes after re-filling the halothane vaporizer, muscle rigor and tachyarrhythmia occurred. Massive myoglobinuria setting in on the day of operation reached its peak on the 1st postoperative day. Only following this were the highest CK activities to be recorded. CK-BB could not be detected at any time.
mesh_terms: D000768:Anesthesia, General; D002675:Child, Preschool; D003402:Creatine Kinase / Q000378:metabolism; D004576:Electromyography; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D006801:Humans; D007527:Isoenzymes; D008305:Malignant Hyperthermia / Q000150:complications / Q000473:pathology*; D009128:Muscle Spasticity / Q000209:etiology; D009212:Myoglobinuria / Q000209:etiology; D013390:Succinylcholine / Q000009:adverse effects
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase; D013390:Succinylcholine; D006221:Halothane
vernacular_title: Maligne Hyperthermie. I. Beobachtungen im Zusammenhang mit ihrem Entstehen und Verlauf.