Electrical activity in cardiac mutant axolotl hearts.
Electrical recordings from the hearts of both cardiac lethal mutant and normal embryos showed the presence of action potentials conducted over the heart tube. Ionic coupling and gap junctions also were observed in both. These results suggest that the absence of heart function in mutant embryos does not result from a defect in electrical activity.
D000200:Action Potentials; D000557:Ambystoma / Q000235:genetics / Q000502:physiology*; D000818:Animals; D004625:Embryo, Nonmammalian / Q000502:physiology; D005804:Genes, Lethal; D006321:Heart / Q000502:physiology*; D007365:Intercellular Junctions / Q000648:ultrastructure; D008854:Microscopy, Electron; D009154:Mutation