Synthesis of a fine neurological electrode by plasma polymerization processing.
This research is part of a continuing program for the development of a coaxial depth electrode for research and diagnostic studies of neurological diseases. The requirements for this electrode include (1) strength and resistance to buckling sufficient to ensure self-forced penetration of brain tissue to a depth of 6 cm; (2) biocompatibility of the materials employed; (3) resistance to brittle fracture; and (4) a total diameter of less than 200 micrometer to minimize tissue damage. Earlier synthesis efforts using chemical vapor deposition techniques have been successful, although the process yield was 40% and an outer insulating layer had yet to be deposited. Plasma polymerization processes have been employed to realize an increase in the yield and provide an outer insulating layer. The starting material is W-26 at.% Re wire, nominally 125 micrometer in diameter. Hexamethyldisilazane(CH3)3SiNHSi(CH3)3 is used to deposit the insulating layers. The paper describes factors influencing the choice of materials, deposition techniques, and properties of electrodes.
D000497:Alloys; D000588:Amines; D001672:Biocompatible Materials; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003300:Copper; D004563:Electrochemistry; D004566:Electrodes; D009462:Neurology / Q000295:instrumentation*; D009532:Nickel; D017646:Organosilicon Compounds; D011108:Polymers; D012825:Silicon; D013193:Stainless Steel
D000497:Alloys; D000588:Amines; D001672:Biocompatible Materials; D017646:Organosilicon Compounds; D011108:Polymers; D013193:Stainless Steel; D003300:Copper; D009532:Nickel; C024548:hexamethylsilazane; D012825:Silicon