title: [Prevention of lymphogenic metastasis in the surgical treatment of rectal cancer].
abstract: It was shown that during radical operations, performed for local spread of rectal cancer (T3--T4, P3--P4), in most patients tumor cells identical to the primary tumor are found in the thoracic duct lymph. To the end of prophylaxis of intraoperative lymphogenic dissemination of tumor cells 71 patients with rectal cancer, spread locally, were subjected preoperatively to endolymphatic infusion of 10% dibunol solution in iodolipol or chromolymphotrast. The preparation was found to be completely deposited in the lymphatic system and to block the routes of lymphogenic dissemination of tumor cells. A considerably reduced number of the postoperative metastases and recurrence of rectal cancer was noted in patients, subjected to radical operations following endolymphatic infusion of oil dibunol solution.
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008196:Lymph / Q000166:cytology; D008198:Lymph Nodes / Q000187:drug effects / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009366:Neoplasm Seeding; D009367:Neoplasm Staging; D011300:Preoperative Care; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*
chemical_list: D000970:Antineoplastic Agents; D002084:Butylated Hydroxytoluene
vernacular_title: O profilaktike limfogennogo metastazirovaniia pri khirurgicheskom lechenii raka priamoĭ kishki.