H-Y antigen in a fertile XY female horse.
The presence of significantly reduced levels of H-Y antigen in the blood of an XY mare is consistent with the view that H-Y genes comprise a system of testis determinants. Loss or suppression of a critical portion of H-Y genes and subthreshold expression of H-Y antigen could account for a failure of testicular differentiation, thereby allowing a measure of ovarian development in an XY embryo.
D000818:Animals; D012734:Disorders of Sex Development / Q000276:immunology / Q000662:veterinary*; D005260:Female; D005298:Fertility; D006182:H-Y Antigen / Q000032:analysis*; D006734:Horse Diseases / Q000276:immunology*; D006736:Horses; D008297:Male
D006182:H-Y Antigen