Reproductive problems in the DES-exposed female.
The records of 25 diethylstilbestrol-exposed women under treatment for reproductive dysfunction were reviewed. A tendency toward pregnancy wastage (5 of 10 patients), ectopic pregnancy (2 of 8 patients), cervical factor infertility (15 of 20 patients), hysterographic abnormalities (15 of 19 patients), and ovulatory dysfunction (10 of 25 patients) was noted. With the exceptions of ovulation induction and cervical cerclage, no means of treatment can be recommended.
D000328:Adult; D002582:Cervix Mucus / Q000187:drug effects; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D005333:Fetus / Q000187:drug effects; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000139:chemically induced; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced; D012098:Reproduction / Q000187:drug effects*; D013997:Time Factors
D004054:Diethylstilbestrol