title: Coagulation properties of fresh-frozin canine plasma during prolonged storage.
abstract: Coagulation properties of fresh platelet-poor canine plasma from 20 dogs were examined before freezing and after storage at intervals of up to 1 year. Prothrombin time and factor V activity did not change in frozen plasma when compared with data obtained after plasma was stored 1 week. When compared with that of fresh plasma, activated partial thromboplastin time shortened and factor VIII activity decreased after freezing and thawing of fresh plasma after 1 week, activated partial thromboplastin time in fresh-frozen plasma gradually shortened during the year of storage. Factor viii activity increased in the first 4 months of storage, but gradually decreased by 1 year.
mesh_terms: D000818:Animals; D001777:Blood Coagulation; D001793:Blood Preservation / Q000662:veterinary*; D004285:Dogs / Q000097:blood*; D005165:Factor V / Q000032:analysis; D005169:Factor VIII / Q000032:analysis; D005615:Freezing; D010314:Partial Thromboplastin Time / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary; D013997:Time Factors
chemical_list: D005165:Factor V; D005169:Factor VIII