title: [Problems of evaluating rare adverse drug reactions using as an example agranulocytosis induced by anti-arrhythmia agents].
mesh_terms: D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000404:Ajmaline / Q000009:adverse effects; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D004359:Drug Therapy, Combination / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008875:Middle Aged; D010653:Phenylbutazone / Q000009:adverse effects; D010672:Phenytoin / Q000009:adverse effects; D011342:Procainamide / Q000009:adverse effects; D011802:Quinidine / Q000009:adverse effects; D012306:Risk
chemical_list: D000889:Anti-Arrhythmia Agents; D000404:Ajmaline; D010672:Phenytoin; D010653:Phenylbutazone; D011802:Quinidine; D011342:Procainamide
vernacular_title: Problematik der Beurteilung seltener Arzneimittelnebenwirkungen am Beispiel der Agranulozytose durch Antiarrhythmika.