title: Chromatin condensation in isolated rat hepatocyte nuclei induced by ribonuclease treatment.
abstract: Ribonuclease treatment of isolated rat hepatocyte nuclei induced a 75% solubilization in hnRNA, a reduction of the quantity of perichromatin fibrils, and a marked condensation of chromatin.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D002843:Chromatin / Q000187:drug effects / Q000648:ultrastructure*; D008099:Liver / Q000648:ultrastructure*; D008115:Liver Regeneration; D008854:Microscopy, Electron; D012332:RNA, Heterogeneous Nuclear / Q000032:analysis*; D051381:Rats; D012260:Ribonucleases / Q000494:pharmacology*
chemical_list: D002843:Chromatin; D012332:RNA, Heterogeneous Nuclear; D012260:Ribonucleases