The effect of thromboresistent surfaces on the development of blood emboli and hemolysis.
Heparinized dog blood was sheared in conicylindrical test cells which had been coated with thrombo-resistant materials. Hemolysis and blood emboli formation in the coated cells were as great or greater than in uncoated polycarbonate cells. These results suggest that materials which resist the buildup of thrombi may still be stimulating emboli formation and red cell damage.
D000818:Animals; D001548:Benzalkonium Compounds; D001672:Biocompatible Materials; D001769:Blood; D002254:Carbonates; D004285:Dogs; D004617:Embolism / Q000209:etiology*; D006108:Graphite; D006461:Hemolysis; D006493:Heparin; D010973:Platelet Adhesiveness; D011108:Polymers; D012709:Serum Albumin; D013499:Surface Properties; D013927:Thrombosis / Q000517:prevention & control; D014885:Waxes
D001548:Benzalkonium Compounds; D001672:Biocompatible Materials; D002254:Carbonates; D011108:Polymers; D012709:Serum Albumin; D014885:Waxes; D006108:Graphite; D006493:Heparin