Cysteine synthesis by Desulfovibrio vulgaris extracts.
Extracts of Desulfovibrio vulgaris were found to contain serine transacetylase and cysteine synthase activities. When extracts were incubated with bisulfite and o-acetylserine, or acetyl coenzyme A plus L-serine, under a hydrogen atmosphere, cysteine was formed. Pyruvate served as a reductant for bisulfite reduction to sulfide and concomitantly provided the acetyl moiety for acetyl coenzyme A formation. Consequently, when extracts were incubated with pyruvate, bisulfite, and L-serine, cysteine synthesis resulted.
D000105:Acetyl Coenzyme A / Q000378:metabolism; D000123:Acetyltransferases / Q000378:metabolism; D003545:Cysteine / Q000096:biosynthesis*; D003547:Cysteine Synthase / Q000378:metabolism; D003901:Desulfovibrio / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism; D051050:Serine O-Acetyltransferase; D013447:Sulfites / Q000378:metabolism
D011773:Pyruvates; D013447:Sulfites; D000105:Acetyl Coenzyme A; D000123:Acetyltransferases; D051050:Serine O-Acetyltransferase; D003547:Cysteine Synthase; D003545:Cysteine