title: Glucuronide and sulphate binding to subcellular fractions of rat liver.
abstract: The binding of glucuronides to various liver subfractions and to bovine serum albumin correlated with their molecular weight. Higher molecular weight glucuronides bound more readily. 4-Methylumbelliferylglucuronide has some of the characteristics of phenolphthaleinglucuronide. Simple phenolic glucuronides were much less retained by various hepatic fractions. Glucuronides were most effectively bound to mitochondrial subfractions. Sulphates of 4-nitrophenol and phenolphthalein were bound to the same degree to bovine serum albumin and hepatic cytosol despite their different molecular structures and weights.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D005965:Glucuronates / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism; D008970:Molecular Weight; D051381:Rats; D012710:Serum Albumin, Bovine / Q000378:metabolism; D013464:Sulfuric Acids / Q000378:metabolism*
chemical_list: D005965:Glucuronates; D013464:Sulfuric Acids; D012710:Serum Albumin, Bovine