title: Necrotizing sialometaplasia of the lip simulating squamous cell carcinoma.
abstract: A case of necrotizing sialometaplasia of the lip in an 68-year-old pipe smoker is described. Necrotizing sialometaplasia is a self-healing non-neoplastic disease probably of ischaemic nature. Thirty-nine cases of sialometaplasia are described in the literature up to early 1979. These cases appeared in the palate, nasal cavity, gingiva, lip, hypopharynx and maxillary sinus. Six cases have also been reported from major salivary glands. Histologically there is necrosis of mucous cells with partial replacement by squamous epithelium. This entity has often been mistaken for squamous or mucoepidermoid carcinoma. One has to be familiar with the existence of necrotizing sialometaplasia in ordeg surgery.
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008047:Lip Diseases / Q000175:diagnosis* / Q000473:pathology; D008048:Lip Neoplasms / Q000175:diagnosis*; D008297:Male; D008679:Metaplasia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology*; D009336:Necrosis; D012466:Salivary Gland Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology