Thymoma and the nephrotic syndrome: a report of a case.
A 48-year-old male presented with the nephrotic syndrome 3 years after resection and irradiation of a thymoma. Renal biopsy revealed membranous glomerulonephritis by electron microscopy. IgA, IgG, and C3 deposition were present in the glomerular basement membrane by immunofluorescence. There was no evidence of other autoimmune diseases or causes of the membranous glomerulonephritis. He has continued to have proteinuria and edema 1 year later.
D000328:Adult; D003176:Complement C3; D005921:Glomerulonephritis / Q000150:complications; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007678:Kidney Glomerulus / Q000276:immunology; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications* / Q000276:immunology / Q000473:pathology; D013945:Thymoma / Q000150:complications* / Q000473:pathology; D013953:Thymus Neoplasms / Q000150:complications* / Q000473:pathology
D003176:Complement C3; D007070:Immunoglobulin A; D007074:Immunoglobulin G