Histocompatibility antigens and antibodies to viral and other antigens in Alzheimer pre-senile dementia.
Alzheimer's disease may arise from an interaction between a conventional infective agent and a particular disease susceptibility (related to the HLA-A or B locus). HLA antigens and antibodies to conventional infective agents were examined in 14 patients with pre-senile dementia. Most of the sample probably suffered Alzheimer's disease, though one subject may have had Pick's disease. No particular HLA type or antibody was associated with the sample.
D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D000914:Antibodies, Viral / Q000032:analysis*; D003704:Dementia / Q000276:immunology*; D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D006680:HLA Antigens