Low plasma levels of pancreatic polypeptide in obesity.
Plasma levels of pancreatic polypeptide (PP) were studied in a group of 22 normal and 22 obese subjects after an overnight fast. In a second group of 10 normal and 13 obese adults, PP secretion was stimulated by a protein-rich meal. The results indicate lower fasting PP values in the obese subjects and a decreased response during the second phase of the meal-induced secretion. This could suggest a possible role of PP in obesity.
D000328:Adult; D001786:Blood Glucose; D004032:Diet; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood*; D010191:Pancreatic Polypeptide / Q000097:blood*
D001786:Blood Glucose; D010191:Pancreatic Polypeptide