Intra-articular osmic acid in rheumatoid arthritis: five years' experience.
Two hundred and one patients (305 knees) with rheumatoid arthritis received intra-articular osmic acid in one or both knees. Assessment was based on pain relief, warmth, tenderness, size and presence of effusion, degree of synovial thickening and range of pain-free movement. Satisfactory results were obtained in 61% at one year gradually reducing to 22% over a five-year period. If only those knees with none or minimal joint damage were considered, then a satisfactory result was obtained in a higher percentage, 74% at one year and 38% at five years.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged; D009992:Osmium / Q000627:therapeutic use*; D009993:Osmium Tetroxide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D009992:Osmium; D009993:Osmium Tetroxide