title: Efficacy of albendazole and levamisole in sheep against Thysanosoma actinioides and Haemonchus contortus from the Edwards Plateau, Texas.
abstract: Lambs naturally infected with Thysanosoma actinioides and naturally and experimentally infected with Haemonchus contortus were used in a controlled experiment to determine the anthelmintic activity of albendazole as compared with levamisole. The lambs were given 10,000 H contortus larvae 25 to 35 days before treatment, were slaughtered 7 to 9 days after treatment, and were housed on concrete from the time of treatment until slaughter. In lambs given doses of 7.5 mg or 3.8 mg of albendazole/kg or 7.5 mg of levamisole/kg, reductions in numbers of H contortus were 99%, 85%, and 98%, respectively. Reductions in numbers of T actinioides were 98%, 45%, and 0% respectively, as compared with untreated controls.
mesh_terms: D015766:Albendazole; D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D002590:Cestode Infections / Q000188:drug therapy / Q000662:veterinary*; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary*; D007978:Levamisole / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D013781:Texas; D014252:Trichostrongyloidiasis / Q000662:veterinary*
chemical_list: D001562:Benzimidazoles; D007978:Levamisole; D015766:Albendazole