Effects of tranylcypromine on the concentration of some trace amines in the diencephalon and hippocampus of the rat.
Concentrations of 4 trace amines in diencephalon and hippocampus of the rat were measured by integrated-ion-current mass spectrometry after administration of the antidepressant drug, tranylcypromine. Much larger increases were observed for 2-phenylethylamine and tryptamine than for m- and p-tyramine.
D000818:Animals; D004027:Diencephalon / Q000187:drug effects / Q000378:metabolism*; D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009928:Organ Specificity; D010627:Phenethylamines / Q000378:metabolism*; D051381:Rats; D014191:Tranylcypromine / Q000494:pharmacology*; D014363:Tryptamines / Q000378:metabolism*; D014439:Tyramine / Q000378:metabolism*
D010627:Phenethylamines; D014363:Tryptamines; D014191:Tranylcypromine; D014439:Tyramine