title: [Anxiolysis and reduction of subjectively scaled "strain" in cognitive stress by means of pindolol].
abstract: Based upon suggestions of Lader (1976) about a diagnostic scale of various anxiety states it is discussed if beta-blockers influence mainly the peripheric vegetative symptoms of anxiety and stress and tranquilizers mainly cognitive anxiety. Results of a study in 51 labile volunteers between 19 and 26 years of age are reported. After a six weeks treatment with pindolol compared to chlordiazepoxide and placebo a significant reduction of trait anxiety after beta-blocker treatment was observed. These effects resembled those usually seen after tranquilizer application.
mesh_terms: D000328:Adult; D001007:Anxiety; D002707:Chlordiazepoxide / Q000627:therapeutic use; D004341:Drug Evaluation; D006801:Humans; D009497:Neurotic Disorders / Q000188:drug therapy; D010869:Pindolol / Q000627:therapeutic use*; D010919:Placebos; D013315:Stress, Psychological / Q000188:drug therapy*; D011795:Surveys and Questionnaires
chemical_list: D010919:Placebos; D002707:Chlordiazepoxide; D010869:Pindolol
vernacular_title: Anxiolyse und Reduktion der subjektiv skalierten "Anspannung" bei kognitivem Stress durch Pindolol.