Response of insulin receptors to oral glucose in normal subjects.
Insulin binding to circulating monocytes was studied in ten male volunteers before and 1, 2, and 5 hours after the oral intake of 100 g of glucose. Results indicate an increase in the specific cell binding fraction with a change in receptor affinity 5 hours after glucose. Since the same changes appear 3 hours after food intake they are probably not directly induced by insulinemia.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005947:Glucose; D006801:Humans; D008297:Male; D009000:Monocytes / Q000187:drug effects; D011972:Receptor, Insulin / Q000187:drug effects*
D001786:Blood Glucose; D011972:Receptor, Insulin; D005947:Glucose