title: A symbiotic relationship of energy metabolism between a 'non-glycolytic' mammalian red cell and the liver.
abstract: The red cell of newborn pig loses the ability to carry out glycolysis within a month after birth. The metabolic energy source for this 'non-glycolytic' mammalian red cell is unknown. Hepatectomy of an adult pig results in the loss of red cell ATP with a characteristic half-time of 7--8 h which is identical to the rate with which ATP disappears in the pig cells under in vitro substrate-free incubation. Exposure of pig red cells with either normal or depleted levels of ATP to isolated hepatocytes causes a net synthesis of red cell ATP during a 12 h incubation. These findings suggest that a symbiotic relationship of energy metabolism may exist between the red cell and the liver of the pig.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D004734:Energy Metabolism; D004912:Erythrocytes / Q000378:metabolism*; D006498:Hepatectomy; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D013552:Swine
chemical_list: D000255:Adenosine Triphosphate