Ischaemic heart disease in young hypertensive women.
The association between hypertension and ischaemic heart disease was explored in a retrospective analysis of 50 severely hypertensive premenopausal women (presenting diatolic pressure greater than or equal to 120 mmHg) under 45 years of age who were seen over a seven-year period. Twenty-two per cent of these patients had angina pectoris, and 38 per cent had Minnesota code 4-1 or 5-1 changes on the resting electrocardiogram. The contribution of other risk factors, including smoking habits, was assessed: 72 per cent of the patients smoked; significantly less smoking was found among two groups of age-matched women with less severe hypertension [diastolic pressures of 90 to 104 mmHg (n=50) and 105 to 119 mmHg (n=50)]. In these latter groups, only one patient had angina pectoris and none had 4-1 or 5-1 changes on the electrocardiogram.
D000328:Adult; D000367:Age Factors; D000787:Angina Pectoris / Q000209:etiology / Q000503:physiopathology; D003327:Coronary Disease / Q000209:etiology*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies; D012306:Risk; D012907:Smoking / Q000150:complications