Identification of tetrahydronorharmane (tetrahydro-beta-carboline) in human blood platelets.
The present paper shows that tetrahydronorharmane (tetrahydro-beta-carboline) exists in human platelets. The concentration of tetrahydronorharmane in platelets from 10 ml platelet rich plasma was in the range of 9.3 to 25.6 pmol (n=8). Ingestion of tryptamine hydrochloride (n=4) three times daily for three consecutive days and of 19.6 mmol D,L-tryptophan (n=7) the evening (10 p.m.) before the blood collection did not lead to an increase of tetrahydronorharmane in platelets.
D000328:Adult; D001792:Blood Platelets / Q000032:analysis* / Q000378:metabolism; D002243:Carbolines / Q000097:blood*; D005260:Female; D006801:Humans; D007211:Indoles / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014363:Tryptamines; D014364:Tryptophan
D002243:Carbolines; D007211:Indoles; D014363:Tryptamines; C009804:tryptoline; D014364:Tryptophan