PUVA-induced repigmentation of vitiligo: scanning electron microscopy of hair follicles.
PUVA-i-duced repigmentation of vitiligo was studied using both the split-dopa reaction and scanning electron microscopy. Proliferation of hypertrophic, Dopa-positive melanocytes were observed in the lower portion of some hair follicles, whereas other giant melanocytes were observed along the middle portion. The existence of a melanocyte reservoir in human hair follicles is postulated.
D000328:Adult; D002455:Cell Division; D005260:Female; D006197:Hair / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000166:cytology; D008730:Methoxsalen / Q000627:therapeutic use*; D010778:Photochemotherapy; D012880:Skin Pigmentation / Q000187:drug effects*; D014820:Vitiligo / Q000188:drug therapy / Q000473:pathology*
D008730:Methoxsalen