Age related distribution of serum immunoglobulin concentration in 1003 healthy children and adults.
IgG, IgA and IgM serum concentrations were determined in 605 healthy children and 398 adults, using a radial immunodiffusion technique. IgG levels were found to be high at birth, fall sharply at two weeks of age, reach a minimum at 3 months and then gradually rise to adult levels which are attained by the age of 9 years. IgA and IgM are low at birth, rise gradually and reach adult levels by 17-18 years. No significant differences, between male and female subjects were found in each of the age groups studied.
D000293:Adolescent; D000328:Adult; D000375:Aging; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012016:Reference Values; D012737:Sex Factors
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins