Hapten-specific unresponsiveness in mice. II. Fate and distribution of 14C-TNBSA injected at tolerogenic doses.
TNBSA injected at tolerogenic doses with a trace label of 14C showed an immediate fixation on serum proteins, red cells, lymphoid cells and, as far as could be determined, all organs in the body. The fixation on lymphoid cells was non-specific, at least initially. These results are discussed in relation to the mechanism of tolerance induction by TNBSA.
D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006241:Haptens / Q000276:immunology; D007108:Immune Tolerance; D008297:Male; D051379:Mice; D009578:Nitrobenzenes / Q000276:immunology*; D013154:Spleen / Q000378:metabolism; D014302:Trinitrobenzenesulfonic Acid / Q000276:immunology* / Q000378:metabolism
D006241:Haptens; D009578:Nitrobenzenes; D014302:Trinitrobenzenesulfonic Acid