[Erythrocyte density distribution disorders in infants with respiratory regulation disorders].
The frequency distribution of the density of erythrocytes was investigated in 22 babies by using the method of Danon and Marikovsky. This investigation seems to be a very suitable method for identifying minimal alterations in the oxygen transport system. In all 22 babies typical S-like density distribution curves were observed similar to those of adults. Eight of the babies with clinically demonstrable disorders in respiration control (ARS) were taken as one group. In comparison with the control group (14 babies) it could be shown that the erythrocytes of the ARS-babies had a lower density than the erythrocytes of normal babies. This difference proved to be statistically significant. No difference between control group and ARS-group could be shown with respect to the distribution of size of the erythrocytes, the mean cell hemoglobin concentration (MCHC), and the mean cell volume (MCV). We assume that the deviation in density distribution of erythrocytes from normal in the ARS-group may be attributed to biochemical changes provoked by the chronical hypoxia. It can be stated that, independent of the interpretation of this phenomenon, a new additional factor could be found for the identification of risks for ARS and possibly for the sudden infant death syndrome (SIDS).
D001049:Apnea / Q000097:blood*; D003720:Densitometry; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000166:cytology*; D005260:Female; D006454:Hemoglobins; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood*; D008297:Male
D006454:Hemoglobins
Verschiebung der Dichteverteilung von Erythrocyten bei Säuglingen mit Atemregulationsstörungen.