An etiologic survey of clinical factors in cervical intraepithelial neoplasia: a transverse retrospective study.
In this retrospective survey 235 patients were studied: 123 patients with cervical intraepithelial neoplasia (CIN) and 112 controls. Fourteen epidemiologic variables were reviewed. The stepwise logistic multiple regression analysis demonstrated that age at first sexual contact was the variable most related to CIN appearance, followed by the occupation of the husband. School attendance and socioeconomic indices of the patients' fathers, husbands or partners were lower in the CIN group, as shown in the descriptive analysis. Age at first pregnancy was also found to be lower among CIN patients. Promiscuity and contraception did not seem to play a significant role in the incidence of neoplastic disease. A carcinogenic model is proposed.
D000328:Adult; D000367:Age Factors; D002278:Carcinoma in Situ / Q000209:etiology*; D003075:Coitus; D005260:Female; D006801:Humans; D012044:Regression Analysis; D012189:Retrospective Studies; D012959:Socioeconomic Factors; D002578:Uterine Cervical Dysplasia / Q000209:etiology*; D002583:Uterine Cervical Neoplasms / Q000209:etiology*