Gas gangrene in a wound treated without skin closure: a case report.
Clostridial myonecrosis developed in a compound tibial fracture wound left open after extensive surgical debridement. The patient survived after having a below-knee amputation and postoperative erythromycin. Prophylactically administered cephalothin failed to prevent the clostridial infection.
D000328:Adult; D005738:Gas Gangrene / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D013978:Tibial Fractures / Q000150:complications / Q000473:pathology / Q000601:surgery*
D010406:Penicillins