Lithium transport across the RBC membrane. A study of genetic factors.
The measurement of the ratio of RBC to plasma lithium ion levels in vitro in 291 members of 120 families indicated that genetic factors contribute substantially to interindividual variability in the lithium ion distribution across the RBC membrane. These factors affect the lithium-sodium ion exchange system that determines the lithium ion distribution.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004910:Erythrocyte Membrane / Q000378:metabolism*; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005838:Genotype; D006801:Humans; D008094:Lithium / Q000097:blood*; D008297:Male; D008875:Middle Aged
D008094:Lithium