Complete fractures of the femur in Paget's disease of bone.
Complete fractures through bone affected by Paget's disease may not deserve their innocent reputation. This retrospective study of 182 such femoral fractures, the largest reported series to date, was carried out to discover the behaviour of these fractures in the absence of specific therapy for the Paget's disease. Most previous series have concluded that healing is uneventful but the findings in these patients from the West Midlands do not bear this out. After exclusion of the early deaths, the overall incidence of non-union was 40 per cent, the main problems being posed by the subtrochanteric fractures and those of the upper shaft. Although callus may be abundant, it may itself be involved in the disease process and is not a reliable sign of union. Based on these observations, suggestions for management in the different regions of the femur are made.
D000368:Aged; D005260:Female; D005264:Femoral Fractures / Q000209:etiology* / Q000601:surgery; D005265:Femoral Neck Fractures / Q000209:etiology / Q000601:surgery; D005593:Fracture Fixation, Internal / Q000379:methods; D005598:Fractures, Spontaneous / Q000209:etiology* / Q000601:surgery; D006620:Hip Fractures / Q000209:etiology / Q000601:surgery; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000150:complications*; D012189:Retrospective Studies; D014945:Wound Healing