[Effect of antihypertensive compounds on the hypothalamic regulation of baroreceptor reflexes].
In experiments on cats the effect of neurotropic drugs on the baroreceptor reflexes changes produced by stimulation of the hypothalamus was investigated. It is shown that diazepam, pentobarbital and oxylidin decrease vasomotor responses under hypothalamic stimulation not only because of the depression of the descending activation of the spinal cord vasomotor neurones processes, but also as a result of suppression of the baroreceptor reflexes hypothalamic regulation. Clonidine and dopegyt had no influence on the baroreflexes hypothalamic regulation.
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D004558:Electric Stimulation; D006614:Hindlimb / Q000098:blood supply; D007031:Hypothalamus / Q000187:drug effects*; D007422:Intestines / Q000098:blood supply; D011311:Pressoreceptors / Q000187:drug effects*; D012018:Reflex / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects; D014661:Vasoconstriction / Q000187:drug effects
D000959:Antihypertensive Agents
Vliianie antigipertenzivnykh soedineniĭ na gipotalamicheskuiu reguliatsiiu baroretseptornykh refleksov.