X-linked recessive retinitis pigmentosa and vitreous fluorophotometry. A study of female heterozygotes.
Vitreous fluorophotometry was used to assess the functional integrity of the blood-retinal barrier in four female carriers of X-linked recessive retinitis pigmentosa. Abnormal findings in all four carriers suggest that a defect in the blood-retinal barrier, detectable by vitreous fluorophotometry, is a sensitive means by which carriers can be identified.
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005451:Fluorescein Angiography; D005452:Fluoresceins / Q000032:analysis; D005470:Fluorometry / Q000379:methods*; D006580:Genetic Carrier Screening / Q000379:methods*; D006801:Humans; D010375:Pedigree; D010783:Photometry / Q000379:methods; D012174:Retinitis Pigmentosa / Q000235:genetics*; D012729:Sex Chromosome Aberrations; D014822:Vitreous Body; D014960:X Chromosome
D005452:Fluoresceins