title: Cryolesions of bone. An experimental study. part I: Examinations in technique of controlled cryolesion on bone.
abstract: Three different approaches of freezing rabbit tibia bones are demonstrated. Intramedullary freezing seems to be the safest method to avoid soft tissue necrosis. Bone specimens removed immediately after the freezing-thawing process showed electron optically evidence of irreversible damage of bone cells in all cases.
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000293:injuries* / Q000648:ultrastructure; D003452:Cryosurgery / Q000009:adverse effects*; D005615:Freezing; D006253:Haversian System / Q000648:ultrastructure; D011817:Rabbits; D013977:Tibia / Q000293:injuries*