Metabolism of naphthalene by pseudomonads: salicylaldehyde as the first possible inducer in the metabolic pathway.
Pseudomonas ATCC 17483 produced enzymes for naphthalene metabolism when growing in a medium containing succinate and naphthalene. Mutants for naphthalene metabolism produced by treatment with N-methyl-N'-nitro-N-nitrosoguanidine were able to produce these enzymes only when the metabolic pathway was intact as far as salicylaldehyde, which was therefore identified as the first possible inducer.
D000445:Aldehyde Oxidoreductases / Q000096:biosynthesis; D000446:Aldehyde-Lyases / Q000096:biosynthesis; D000447:Aldehydes / Q000378:metabolism*; D004790:Enzyme Induction; D009154:Mutation; D009281:Naphthalenes / Q000096:biosynthesis / Q000378:metabolism*; D010105:Oxygenases / Q000096:biosynthesis; D011549:Pseudomonas / Q000201:enzymology / Q000378:metabolism*
D000447:Aldehydes; D009281:Naphthalenes; C013243:salicylaldehyde; D010105:Oxygenases; C021834:arene monooxygenase (epoxidizing); D000445:Aldehyde Oxidoreductases; C024246:salicylaldehyde dehydrogenase; C024247:2'-hydroxybenzalpyruvate aldolase; D000446:Aldehyde-Lyases