A comparison of the relative efficacy of CAPD and hemodialysis in the control of solute concentration.
Metabolite concentrations found in patients on both continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis are predicted by means of a theoretical transport model. Effects of variation in parameters such as generation rate, mass transfer, coefficients and residual renal clearance are studied. The information obtained indicates that CAPD is as effective as hemodialysis in reducing the concentrations of low molecular weight metabolites occurring in the "average" ESRD patient. CAPD becomes increasingly more effective than hemodialysis as molecular weight increases.
D000553:Ambulatory Care; D001692:Biological Transport; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D005110:Extracellular Space / Q000378:metabolism; D007424:Intracellular Fluid / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000378:metabolism; D007688:Kidneys, Artificial; D008954:Models, Biological; D010530:Peritoneal Dialysis / Q000379:methods*; D006435:Renal Dialysis; D012996:Solutions
D012996:Solutions; D003404:Creatinine