Immune complexes in scabies. In vitro study of the serum C1q fixation in the presence of mite and unparasited human scale extracts.
The in vitro addition of mice or human unparasited scale extracts to the serum of 8 patients with scabies and 5 healthy controls did not significantly modify the fixation of 125I-C1q as compared to control tubes (serum with physiological saline). These results suggest that antigens or substances derived from the scabies mite are not involved in the immune complexes present in the serum of the parasited patients.
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex; D002648:Child; D003172:Complement C1 / Q000276:immunology*; D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D008297:Male; D008925:Mites / Q000276:immunology*; D012532:Scabies / Q000276:immunology*
D000936:Antigen-Antibody Complex; D003172:Complement C1