Rheological and functional impairments in cholesterol-loaded human erythrocytes.
Decreased deformability, slightly increased suspension viscosity and retarded oxygen egrees were observed in cholesterol-loaded, human erythrocytes. These functional changes resulted from the decreased membrane fluidity induced by cholesterol.
D001809:Blood Viscosity; D002784:Cholesterol / Q000097:blood* / Q000502:physiology; D004910:Erythrocyte Membrane / Q000032:analysis; D004912:Erythrocytes / Q000032:analysis / Q000187:drug effects*; D006801:Humans; D008560:Membrane Fluidity; D010100:Oxygen / Q000097:blood; D010743:Phospholipids / Q000097:blood
D010743:Phospholipids; D002784:Cholesterol; D010100:Oxygen