title: Roentgenographic changes during long-term diphenylhydantoin therapy.
abstract: Diphenylhydantoin (Dilantin) is a well known anticonvulsant with well documented effectiveness. The complications, unfortunately, are multiple and well recognized clinically. This paper deals with the roentgenographic changes encountered in long-term diphenylhydantoin use. Some of these changes, which are not clinically readily apparent, may alert unwary physicians in the recognition of diphenylhydantoin-induced disease.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology; D001847:Bone Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000187:drug effects; D002526:Cerebellar Diseases / Q000139:chemically induced; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000139:chemically induced; D010018:Osteomalacia / Q000139:chemically induced / Q000000981:diagnostic imaging; D010672:Phenytoin / Q000009:adverse effects*; D011859:Radiography; D012279:Rickets / Q000139:chemically induced / Q000000981:diagnostic imaging; D012886:Skull / Q000000981:diagnostic imaging
chemical_list: D010672:Phenytoin