Quantitative correlation of anesthetic potencies of halogenated hydrocarbons with boiling point and molecular connectivity.
The anesthetic potencies of halogenated hydrocarbons are found by the regression analysis to have a fairly good correlation with boiling point and first-order valence molecular connectivity (1 chi v). Also a significant correlation is found between boiling point and 1 chi v themselves.
D000777:Anesthetics; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006846:Hydrocarbons, Halogenated / Q000494:pharmacology*; D008968:Molecular Conformation; D013329:Structure-Activity Relationship
D000777:Anesthetics; D006846:Hydrocarbons, Halogenated