X-ray and neutron scattering density profiles of the intact human red blood cell membrane.
Hemoglobin-free human red blood cell membranes have been prepared with glutaraldehyde to maintain an intact structure on partial dehydration. Treatment of resealed ghosts with poly(L-lysine) produced an essentially constant structural unit and permitted correlation of electron microscopy results with x-ray and neutron diffraction profiles. These profiles provide detailed information, for the intact membrane, on the location and relative distribution of lipids and proteins.
D004910:Erythrocyte Membrane / Q000378:metabolism / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D006801:Humans; D008563:Membrane Lipids; D008565:Membrane Proteins; D009502:Neutrons; D012542:Scattering, Radiation; D013049:Spectrin / Q000378:metabolism; D014867:Water; D014961:X-Ray Diffraction
D008563:Membrane Lipids; D008565:Membrane Proteins; D014867:Water; D013049:Spectrin