title: Catecholamine metabolites in amniotic fluid as indicators of intrauterine stress.
abstract: The catecholamine metabolites HMPG and VMA have been determined in samples of amniotic fluid in 38 uncomplicated pregnancies, seven cases of IUGR, and six cases of diabetes. A successive increase of HMPG and VMA was found toward the end of the pregnancy. HMPG and particularly the HMPG/VMA ratio were significantly higher in the amniotic fluid of the growth-retarded fetuses than in the uncomplicated cases. No significant difference was found between the diabetic and uncomplicated cases.
mesh_terms: D000653:Amniotic Fluid / Q000032:analysis*; D002395:Catecholamines / Q000378:metabolism*; D002849:Chromatography, Gas; D005260:Female; D005317:Fetal Growth Retardation / Q000378:metabolism*; D005865:Gestational Age; D006018:Glycols / Q000032:analysis*; D006801:Humans; D013058:Mass Spectrometry; D008734:Methoxyhydroxyphenylglycol / Q000032:analysis*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011254:Pregnancy in Diabetics / Q000378:metabolism*; D014642:Vanilmandelic Acid / Q000032:analysis*
chemical_list: D002395:Catecholamines; D006018:Glycols; D008734:Methoxyhydroxyphenylglycol; D014642:Vanilmandelic Acid