title: Role of teichoic acid in the binding of Staphylococcus aureus to nasal epithelial cells.
abstract: The role of teichoic acid in the adherence of Staphylococcus aureus to nasal epithelial cells was investigated. Epithelial cells treated with teichoic acid demonstrated decreased binding of S. aureus. A 71% reduction of adherence was noted with teichoic acid-treated epithelial cells as compared with controls (P less than 0.001). Reduction in adherence of S. aureus was also noted with lipoteichoic acid (obtained from streptococci)-treated epithelial cells. The data provide evidence that teichoic acid mediates the adherence of S. aureus to nasal mucosal cells.
mesh_terms: D001665:Binding Sites; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D009297:Nasal Mucosa / Q000166:cytology / Q000378:metabolism*; D011955:Receptors, Drug / Q000378:metabolism*; D013211:Staphylococcus aureus / Q000378:metabolism*; D013682:Teichoic Acids / Q000378:metabolism*
chemical_list: D011955:Receptors, Drug; D013682:Teichoic Acids