Enflurane-associated hepatitis.
A 57-yr-old female with no previous history of liver disease was exposed to enflurane during three separate surgeries over a 12-mo period. After the second and third exposures, she developed systemic symptoms and abnormal liver tests similar to those seen in halothane hepatitis. A liver biopsy obtained after the third exposure was compatible with drug-induced hepatitis. This is the first reported case of enflurane-associated hepatitis.
D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004737:Enflurane / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged
D004737:Enflurane