The nonspecificity of diffuse pulmonary uptake of 67Ga on 24-hour images.
Eighteen patients who underwent whole-body scintigraphy 24 and 48 hours after intravenous injection of 67Ga-citrate were evaluated retrospectively. At 24 hours, 7 of the 16 normal patients (44%) and both abnormal patients demonstrated significant pulmonary uptake. However, by 48 hours, only 2 normal patients (12%) remained positive, while both abnormal patients continued to show significant pulmonary activity. The authors conclude that 48-hour 67Ga images offer improved specificity and uncompromised sensitivty in patients with diffuse pulmonary disease.
D000328:Adult; D000368:Aged; D005189:False Positive Reactions; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D007223:Infant; D008168:Lung / Q000000981:diagnostic imaging*; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013997:Time Factors
D005710:Gallium Radioisotopes