title: [Van der Woude's syndrome].
abstract: Seven males and seven females from three different families with the syndrome of cleft lip--palate and congenital lower--lip pits, also called van der Wound's are described. An autosomal dominant pattern of inheritance was compatible in the three families. The incomplete penetrance and variable expressivity of the syndrome are analyzed and some aspects of genetic counseling are discussed on the basis of empirical recurrence risks already established for this disorder.
mesh_terms: D002675:Child, Preschool; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree; D013577:Syndrome
vernacular_title: Síndrome de van der Woude.