title: The inhibition of dihydrofolate reductase by folate analogues: structural requirements for slow- and tight-binding inhibition.
mesh_terms: D003201:Computers; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D005493:Folic Acid Antagonists; D007700:Kinetics; D011485:Protein Binding; D013291:Streptococcus / Q000201:enzymology; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000378:metabolism
chemical_list: D005493:Folic Acid Antagonists; D005492:Folic Acid; D013762:Tetrahydrofolate Dehydrogenase