title: Elaboration of microscopic and macroscopic theories of enzyme action: with implications for enzyme evolution, reversibility and kinetics.
mesh_terms: D001665:Binding Sites; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological; D011487:Protein Conformation; D013816:Thermodynamics
chemical_list: D004798:Enzymes