Early prostaglandin E synthesis is an obligatory event in the induction of cell proliferation in mouse epidermis in vivo by the phorbol ester TPA.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D005260:Female; D007213:Indomethacin / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D010704:Phorbols / Q000494:pharmacology*; D011458:Prostaglandins E / Q000096:biosynthesis*; D012867:Skin / Q000378:metabolism*; D012879:Skin Physiological Phenomena; D013329:Structure-Activity Relationship; D013755:Tetradecanoylphorbol Acetate / Q000031:analogs & derivatives / Q000494:pharmacology*
D010704:Phorbols; D011458:Prostaglandins E; D013755:Tetradecanoylphorbol Acetate; D007213:Indomethacin