title: Experiments in mice and rats on the induction of joint lesions following injections of serum and in chronic virus infection.
abstract: Rats and mice, in contrast to rabbits, appeared to be insusceptible to the development of rheumatoid-like joint lesions on repeated injections with bovine serum--the serum sickness model. Persistent infection of mice with the lactic dehydrogenase virus likewise failed to induce joint lesions.
mesh_terms: D000818:Animals; D001769:Blood; D002417:Cattle; D005260:Female; D006386:Hemagglutination Tests; D007592:Joint Diseases / Q000473:pathology; D007668:Kidney / Q000473:pathology; D007772:Lactate dehydrogenase-elevating virus; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA; D008819:Mice, Nude; D011817:Rabbits; D051381:Rats; D012713:Serum Sickness / Q000209:etiology*