[Comparative evaluation of the treatment of radiation skin injuries with oxycort ointment and Peruvian balsam].
The regenerating action of Peruvian balm and oxycort was compared in experiments on rats with experimental radiation skin injuries. Radiation skin ulcers entailed severe morphological and biochemical abnormalities, there was also observed an unstable healing provided the treatment was not applied. Oxycort ointment slightly reduced the period of healing. However, formation of secondary microdefects was conducive to recurrent ulcer in the future. Peruvian balm exerted a pronounced bactericidal action, strongly intensified the reparative processes, and, therefore, reduced the period of healing and favoured the differentiation of the cicatricial tissues that led to a stable healing of the ulcers.
D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001453:Balsams / Q000627:therapeutic use*; D004338:Drug Combinations / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D006854:Hydrocortisone; D008297:Male; D009824:Ointments; D010118:Oxytetracycline / Q000627:therapeutic use*; D011855:Radiodermatitis / Q000188:drug therapy*; D051381:Rats; D012883:Skin Ulcer / Q000188:drug therapy; D013997:Time Factors; D014197:Trees; D014945:Wound Healing / Q000187:drug effects
D000893:Anti-Inflammatory Agents; D001453:Balsams; D004338:Drug Combinations; D009824:Ointments; C008744:hydrocortisone, oxytetracycline drug combination; C025080:Peruvian balsam; D006854:Hydrocortisone; D010118:Oxytetracycline
Sravnitel'naia otsenka lecheniia luchevykh povrezhdeniĭ kozhi oksikortovoĭ ma'iu i peruanskim bal'zamom.