title: A technique for preclotting vascular grafts.
abstract: Porous vascular grafts can be safely and securely sealed prior to use by a thirty-minute soak in cryoprecipitate followed by a ten-minute immersion in topical thrombin. This technique does not use the patient's blood and works in a patient fully anticoagulated with heparin. It has provided absolute graft competence in a series of 12 patients with valve conduits and 6 with patch enlargement of the ascending aorta.
mesh_terms: D001807:Blood Vessel Prosthesis / Q000379:methods*; D003080:Cold Temperature; D003331:Coronary Vessels / Q000601:surgery; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D013917:Thrombin
chemical_list: D013917:Thrombin