Assessment of some variables affecting the blanching activity of betamethasone 17-valerate cream.
The effect of concentration and occlusion time on the ability of Betnovate cream (betamethasone 17-valerate 0.1%) to produce skin blanching was assessed. Generally, increased concentration or occlusion time produce an increase in the degree of blanching observed, however, a plateau stage is eventually reached where no further increase of blanching occurs.
D001623:Betamethasone / Q000031:analogs & derivatives*; D001624:Betamethasone Valerate / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D012867:Skin / Q000187:drug effects*; D013997:Time Factors
D001623:Betamethasone; D001624:Betamethasone Valerate