Therapy of renal osteodystrophy with dihydrotachysterol in non-dialyzed patients.
Two non-dialyzed patients with severe uremic bone disease were treated successfully with dihydrotachysterol (DHT). In each case, dramatic clinical improvement was noted in several weeks and this was verified by biochemical, radiologic and histologic measurements. Although DHT has been utilized previously in combination with dialysis, its documented effectiveness in the absence of the latter therapy has not previously been reported.
D000328:Adult; D001842:Bone and Bones / Q000473:pathology; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D004097:Dihydrotachysterol / Q000627:therapeutic use*; D005260:Female; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D012886:Skull / Q000000981:diagnostic imaging
D004097:Dihydrotachysterol