title: Efficacy of albendazole against Fasciola hepatica in cattle.
abstract: Albendazole in drench formulation was administered to calves 16 weeks after infection with 400 metacercariae of Fasciola hepatica. In separate experiments, albendazole at dose levels of 10 or 15 mg/kg reduced the fluke burden by 92.84 per cent and 95.0 per cent, respectively. In another experiment, a dose level of 7.5 mg/kg given once, twice with a two-week interval, or twice with a three-week interval reduced the mean fluke burden by 43.75 per cent, 72.29 per cent and 90 per cent, respectively.
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D001562:Benzimidazoles; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000469:parasitology; D004341:Drug Evaluation / Q000662:veterinary; D005210:Fasciola hepatica; D005211:Fascioliasis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000871:Anthelmintics; D001562:Benzimidazoles