title: Infantile nephrotic syndrome with diffuse mesangial sclerosis: a disturbance of glomerular basement membrane development?
abstract: Ultrastructural examinations of renal glomeruli in a case of diffuse mesangial sclerosis revealed a hitherto unknown type of alteration of the basement membranes ("cloudy pattern") which suggests a disturbance of glomerular basement membrane development as the basic mechanism which leads to therapy resistent infantile nephrotic syndrome.
mesh_terms: D001485:Basement Membrane / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007678:Kidney Glomerulus / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009404:Nephrotic Syndrome / Q000473:pathology*; D011379:Prognosis; D012598:Sclerosis / Q000473:pathology