title: [Comparative characteristics of the changes in the protein makeup and immunobiological properties of the cerebrospinal fluid and blood serum in experimental trypanosomiasis in rabbits].
abstract: Changes in proteins and immunobiological properties of cerebrospinal fluid and serum of blood during trypanosomosis of rabbits infected with T. ninaekohljakimovae are described. Changes of the protein composition and immunobiological properties in cerebrospinal fluid and serum have been shown to differ in the degree, character and time of their display. The dependence of changes in the concentration of immunoglobulins IgM, IgG, IgA (according to the data of immunoelectrophoresis) of blood serum on its protective properties was investigated. The role of cerebral barrier mechanisms in the formation of immunity in the central nervous system is shown.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D001812:Blood-Brain Barrier; D002490:Central Nervous System / Q000276:immunology; D002555:Cerebrospinal Fluid / Q000276:immunology*; D002556:Cerebrospinal Fluid Proteins / Q000378:metabolism*; D007109:Immunity; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D011817:Rabbits; D013997:Time Factors; D014352:Trypanosomiasis / Q000276:immunology / Q000378:metabolism*
chemical_list: D001798:Blood Proteins; D002556:Cerebrospinal Fluid Proteins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Sravnitel'naia kharakteristika izmeneniĭ belkovogo sostava i immunobiologicheskikh svoĭstv likvora i syvorotki krovi pri éksperimental'nom tripanosomoze krolikov.