Inhibition of Dugesia tigrina auricle regeneration by inhibitors of polyamine synthesis.
Results are presented that indicate polyamine synthesis inhibitors increase the flatworm Dugesia tigrina's auricle regeneration time. This study serves as evidence that endogenous putrescine, spermidine, and spermine are necessary for the flatworm regeneration process.
D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D009952:Ornithine / Q000031:analogs & derivatives* / Q000494:pharmacology; D011073:Polyamines / Q000096:biosynthesis*; D011700:Putrescine / Q000494:pharmacology; D011765:Pyruvaldehyde / Q000494:pharmacology*; D012038:Regeneration / Q000187:drug effects; D013095:Spermidine / Q000494:pharmacology; D013096:Spermine / Q000494:pharmacology; D014419:Turbellaria / Q000187:drug effects / Q000502:physiology*
D000447:Aldehydes; D011073:Polyamines; D013096:Spermine; C025025:alpha-methylornithine; D011765:Pyruvaldehyde; D009952:Ornithine; D013095:Spermidine; D011700:Putrescine