Adult-onset foveomacular pigment epithelial dystrophy.
Thirty-three pateints had adult-onset foveomacular dystrophy. The macular lesions typically resulted in a mild to moderate decrease in vision and appeared as small, yellow, bilateral, slightly elevated, pigment epithelial lesions with areas of hyperpigmentation. The characteristic finding on fluorescein angiography was a ring of hyperfluorescence surrounding an area of hypofluorescence. The electro-oculograms were either normal or slightly subnormal in most cases. This dystrophy appears to have an autosomal dominant transmission.
D000328:Adult; D000368:Aged; D004585:Electrooculography; D004596:Electroretinography; D005128:Eye Diseases / Q000150:complications; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis; D006801:Humans; D008268:Macular Degeneration / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye; D010859:Pigmentation Disorders / Q000150:complications; D011859:Radiography; D014792:Visual Acuity