Granulomatous hepatitis as a manifestation of quinidine hypersensitivity.
Histologic pictures have been conflicting in previous cases of quinidine-associated hepatitis. We report a case of reversible granulomatous hepatitis from quinidine hypersensitivity, with granuloma induction occurring within three days after readministration of quinidine. Fever, urticaria, and mild thrombocytopenia were associated clinical findings. Both light and electron microscopic study results are reported.
D001706:Biopsy; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D004342:Drug Hypersensitivity / Q000150:complications / Q000209:etiology*; D005260:Female; D006099:Granuloma / Q000139:chemically induced; D006801:Humans; D008099:Liver / Q000473:pathology*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy; D011802:Quinidine / Q000009:adverse effects* / Q000627:therapeutic use; D014693:Ventricular Fibrillation / Q000188:drug therapy
D011802:Quinidine