title: Intestinal degradation and absorption of the glycosidic sweeteners stevioside and rebaudioside A.
abstract: Contrary to prior indications, the glycosidic sweeteners stevioside and rebaudioside A are degraded to the diterpenoid aglycone steviol by rat intestinal microflora in vitro. Additional studies with steviol-17-[14C] show almost total absorption from the rat lower bowel following intracecal administration.
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D001652:Bile Ducts / Q000378:metabolism; D002432:Cecum / Q000382:microbiology*; D004224:Diterpenes; D045786:Diterpenes, Kaurane; D005243:Feces / Q000032:analysis; D005960:Glucosides / Q000378:metabolism*; D006027:Glycosides / Q000378:metabolism*; D007408:Intestinal Absorption; D010944:Plants; D051381:Rats; D013729:Terpenes / Q000378:metabolism*
chemical_list: D004224:Diterpenes; D045786:Diterpenes, Kaurane; D005960:Glucosides; D006027:Glycosides; D013729:Terpenes; C012043:stevioside; C025474:rebaudioside A