Raised somatomedin associated with normal growth hormone. A cause of Beckwith-Wiedemann syndrome?
A child with Beckwith-Wiedemann syndrome is described. Growth hormone levels were normal, but circulating somatomedin activity was increased. The role of somatomedins in this condition, and the possibility of a feedback mechanism controlling somatomedin production are discussed.
D005877:Gigantism / Q000097:blood*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007003:Hypoglycemia / Q000097:blood*; D007231:Infant, Newborn; D008297:Male; D013002:Somatomedins / Q000097:blood*; D013577:Syndrome
D013002:Somatomedins; D013006:Growth Hormone