Electron microscopy in iris nevus syndrome.
In a patient with the clinical features of the iris nevus syndrome who was treated for glaucoma a cataract developed later. The sector of iris removed during cataract extraction was examined by electron microscopy and was found to be covered by ectopic corneal endothelium with an underlying atypical Descemet's membrane. Abnormalities in the iris included aggregates of melanophagic cells in the anterior stroma and fibrosis in relation to the ectopic endothelium. These findings suggest that many of the iris abnormalities seen in this disorder occur on a reactive basis.
D002386:Cataract / Q000150:complications; D005134:Eye Neoplasms / Q000150:complications / Q000473:pathology / Q000648:ultrastructure*; D005260:Female; D005901:Glaucoma / Q000150:complications; D006801:Humans; D007498:Iris / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D009506:Nevus / Q000150:complications / Q000473:pathology / Q000648:ultrastructure*; D013577:Syndrome; D014603:Uveal Diseases / Q000150:complications / Q000473:pathology