Analysis of possible toxins in hepatic coma including the removal of mercaptan by albumin-collodion charcoal.
Albumin-collodion coated activated charcoal was found to effectively remove mercaptan in aqueous solution or in "plasma" solution. An initial clearance of 150 ml/min at a flow rate of 200 ml/min could be obtained. The roles of middle molecules, loosely protein-blood molecules, phenols, mercaptan and other molecules were discussed.
D000327:Adsorption; D000418:Albumins; D000818:Animals; D002606:Charcoal; D003101:Collodion; D005978:Glutathione / Q000097:blood; D006464:Hemoperfusion; D006501:Hepatic Encephalopathy / Q000097:blood* / Q000628:therapy; D006801:Humans; D011379:Prognosis; D011485:Protein Binding; D051381:Rats; D013438:Sulfhydryl Compounds / Q000097:blood*; D014118:Toxins, Biological / Q000097:blood*
D000418:Albumins; D013438:Sulfhydryl Compounds; D014118:Toxins, Biological; D002606:Charcoal; D003101:Collodion; D005978:Glutathione