Osteopenia of prematurity: the cause and possible treatment.
By photon absorptiometry, extrauterine bone mineralization in low-birth-weight infants fed a standard commercial formula lags significantly behind intrauterine bone mineralization. In the present study, infants of 28- to 32-week and 33- to 35-week gestational age were studied. The calcium content in a standard formula was increased to provide a daily calcium intake of 220 to 250 mg/kg/day. Phosphate intake was 110 to 125 mg/kg/day. Extrauterine bone mineralization by photon absorptiometry appeared to approximate the intrauterine bone mineralization rate.
D001847:Bone Diseases / Q000178:diet therapy* / Q000209:etiology / Q000378:metabolism; D002113:Calcification, Physiologic; D002118:Calcium / Q000378:metabolism; D002136:Calcium, Dietary / Q000008:administration & dosage*; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000178:diet therapy* / Q000209:etiology / Q000378:metabolism; D010758:Phosphorus / Q000008:administration & dosage / Q000378:metabolism; D014807:Vitamin D / Q000008:administration & dosage / Q000378:metabolism
D002136:Calcium, Dietary; D014807:Vitamin D; D010758:Phosphorus; D002118:Calcium