Clonazepam treatment of insomnia due to sleep myoclonus.
Nocturnal myoclonus has been identified as a cause of disturbed sleep and excessive daytime fatigue. To our knowledge, no therapy has heretofore been available to adequately control this problem. We identified this problem clinically in two patients; in one, the phenomenon was observed with a polygraphic sleep recording. Small doses of clonazepam, 1 mg, before retiring were found to specifically control the myoclonus and allow sleep patterns to return to normal.
D000328:Adult; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000188:drug therapy*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*
D001570:Benzodiazepinones; D002998:Clonazepam