Circulating immune complexes in patients with neoplastic disorders.
A group of 100 patients with various neoplastic disorders and 25 healty subjects were studied by the 125I-Clq and 125I-mRF inhibition tests for the presence of circulating immune complexes in the sera. The presence of circulating immune complexes was detected in 32 and 23% of the 100 patients by the 125I-Clq inhibition test and 125I-mRF inhibition test, respectively. A discrepancy between the two radioimmunoassays in cancer sera may suggest a possibility of the occurrence of quantatively different types of circulating immune complexes in neoplastic disorders.
D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D003172:Complement C1; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000276:immunology*; D011863:Radioimmunoassay / Q000379:methods; D012217:Rheumatoid Factor
D000912:Antibodies, Neoplasm; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D003172:Complement C1; D012217:Rheumatoid Factor