title: Asymptomatic hyperuricaemia and its early treatment.
abstract: Sixteen patients with asymptomatic hyperuricaemia were treated with "Citro-Soda', an urinary alkanlinizing agent, in a dose of 4 g four times daily for one month. Ten of the sixteen patients exhibited a meaningful reduction in serum uric acid (greater than 15%). No adverse effects were noted and various haematological and urinary tests were all normal. 'Citro-Soda' could, therefore, be considered a useful and well-tolerated adjunct in the treatment of hyperuricaemia.
mesh_terms: D001639:Bicarbonates / Q000627:therapeutic use*; D002951:Citrates / Q000627:therapeutic use*; D019343:Citric Acid; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000188:drug therapy; D017693:Sodium Bicarbonate; D013644:Tartrates / Q000627:therapeutic use*; D014527:Uric Acid / Q000097:blood*
chemical_list: D001639:Bicarbonates; D002951:Citrates; D004338:Drug Combinations; D013644:Tartrates; D014527:Uric Acid; D019343:Citric Acid; C020998:sodium bicarbonate, sodium citrate, citric acid, tartaric acid drug combination; D017693:Sodium Bicarbonate