Effects of heroin and naltrexone on plasma prolactin levels in man.
Plasma levels of prolactin were increased following intravenous self-administration of heroin by young men with a history of heroin addiction. Following 10 days of controlled heroin usage, tolerance could be demonstrated to the acute prolactin-releasing effect of heroin. There was no evidence that a single dose of naltrexone affected basal prolactin levels.
D000328:Adult; D003932:Heroin / Q000494:pharmacology*; D006556:Heroin Dependence / Q000097:blood; D006801:Humans; D008297:Male; D009270:Naloxone / Q000031:analogs & derivatives*; D009271:Naltrexone / Q000494:pharmacology*; D011388:Prolactin / Q000097:blood*
D009270:Naloxone; D009271:Naltrexone; D003932:Heroin; D011388:Prolactin