Secondary products of itanoxone.
Itanoxone synthesis by Friedel-Crafts reaction between itaconic anhydride and 2-chlorobiphenyl was studied. Five isomers corresponding to possible impurities were prepared and studied to perfect a reliable and practical method to detect these impurities in itanoxone.
D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000302:isolation & purification; D002090:Butyrophenones / Q000138:chemical synthesis* / Q000302:isolation & purification; D002855:Chromatography, Thin Layer; D006865:Hydrogenation; D000960:Hypolipidemic Agents / Q000138:chemical synthesis* / Q000302:isolation & purification; D007536:Isomerism
D001713:Biphenyl Compounds; D002090:Butyrophenones; D000960:Hypolipidemic Agents; C024140:itanoxone