title: [Hepatosplenic disorders in schistosomiasis (author's transl)].
abstract: Hepatosplenic disorders start in the invasion stage and are from immuno-allergic origin. Then, they develop during the ovular laying stage; hepatic disorders are due to periovular granulomatosis, and splenic disorders are due to reticulo-endothelial system reaction. Their last aspect is the portal fibrosis, called Symmer's "clay pipe", in which HTP is consequent to hepatic disorder and the main cause of splenomegaly. The location of S. japonicum and S. mansoni in pericolic veins explains that hepatic ovular deposits are much more frequent than with S. haematobium that is located in bladder veins. S. intercalatum, living in perirectal veins, may also disseminate some eggs in the liver. HTP most often requires surgical intervention. The diagnostic approach of hepatosplenic disorders in schistosomiasis is described and discussed.
mesh_terms: D006099:Granuloma / Q000469:parasitology; D006801:Humans; D006975:Hypertension, Portal / Q000469:parasitology; D008109:Liver Diseases, Parasitic / Q000209:etiology*; D012548:Schistosoma haematobium; D012549:Schistosoma japonicum; D012550:Schistosoma mansoni; D012552:Schistosomiasis / Q000150:complications*; D013158:Splenic Diseases / Q000469:parasitology*; D013163:Splenomegaly / Q000469:parasitology
vernacular_title: Les manifestations hépatospléniques des bilharzioses.