title: Withdrawal symptoms during the course of imipramine therapy.
abstract: The authors describe 2 cases in which withdrawal symptoms occurred during the course of imipramine therapy, after the patients had failed to take a single daily dose of medication. They note that similar withdrawal symptoms have been noted upon discontinuation of imipramine and its derivatives desipramine and chlorimipramine, but have not--with one exception--been reported in association with other tricyclics.
mesh_terms: D000328:Adult; D003863:Depression / Q000188:drug therapy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007099:Imipramine / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
chemical_list: D007099:Imipramine