[Liver-specific enzymatic activity and radiohepatographic indices in evaluating the functional state of the liver in myocardial infarct].
Data on changes in the blood activity of sorbit dehydrogenase (SDH) and fructose-1-phosphate aldolase (P-1-PA) in blood serum and the findings of radiohepatography in 224 patients with macrofocal and 120 patients with microfocal myocardial infarction are discussed. The studies were conducted in dynamics. Observations showed that SDH and P-1-PA activity grew in the acute period of mycrofocal myocardial infarction. The increase in enzyme activity was most marked in patients with cardiogenic shock. In patients with microfocal myocardial infarctions the increase in the activity of the enzymes studied was mainly encountered when there were signs of congestion in the liver. Radiohepatography revealed disorders of hepatic function in all patients with macrofocal myocardial infarction and in those patients with microfocal infarction who had congestion in the lijer. Changes in the radiogepatogram indices were most marked in patients with myocardial infarction attended by shock and congestion in the liver. The results of the study are evidence that simultaneous tests for SDH and P-1-PA activity in blood serum and radiohepatography give the fullest and most reliable information on the functional condition of the liver in patients with myocardial infarction.
D004796:Clinical Enzyme Tests / Q000379:methods*; D004789:Enzyme Activation; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood; D006333:Heart Failure / Q000175:diagnosis; D006801:Humans; D007064:L-Iditol 2-Dehydrogenase / Q000097:blood; D008099:Liver / Q000000981:diagnostic imaging / Q000201:enzymology*; D008111:Liver Function Tests / Q000379:methods*; D009203:Myocardial Infarction / Q000175:diagnosis*; D011859:Radiography; D012770:Shock, Cardiogenic / Q000175:diagnosis; D013997:Time Factors
D007064:L-Iditol 2-Dehydrogenase; D005634:Fructose-Bisphosphate Aldolase
Aktivnost' pechechno-spetsificheskikh fermentov i pokazateli radiogepatografii v otsenke funktsional'nogo sostoianiia pecheni u bol'nykh infarktom miokarda.