title: Comparison of plasma creatinine determined with the Greiner Selective Analyser GSA II and the glomerular filtration rate.
abstract: 1. Reference values for the plasma creatinine were established using the alkaline picrate method with the Greiner Selective Analyzer GSA II in relation to the Cr 51-EDTA Clearance. Individuals with normal GFR between 93 to 159 ml/min/1.73 m2 had creatinine values in men (n = 65) from 53.7 to 119.5 mumol/l (0.61 to 1.35 mg/100 ml) and in women (n = 59) from 37.7 to 107 mumol/l (0.42 to 121 mg/100 ml). 2. The creatine determinations with the GSA II were compared to those on the Technicon Analyzer, the Beckman Creatinine Analyzer, the Gemsaec-Fast Analyzer and to the enzymatic creatinine method. A good correlation (r = 0.9780-0.984) was observed. 3. With the GSA II and the enzymatic method, bilirubin showed a minor interference which was more marked with the Beckman analyzer.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001322:Autoanalysis / Q000379:methods; D001663:Bilirubin / Q000494:pharmacology; D003404:Creatinine / Q000097:blood*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012737:Sex Factors; D013056:Spectrophotometry, Ultraviolet; D013223:Statistics as Topic
chemical_list: D003404:Creatinine; D001663:Bilirubin