title: [Amitriptyline and imipramine poisoning].
abstract: Two cases of severe poisoning by tricyclic antidepressants (Amitriptylin, Imipramin) are reported. Both patients 3 and 11 years old children, developed a typical clinical picture with cardiovascular, neurological and atropine features. Beside a general supportive management, in one case physostigmin was used as antidote. Alternative treatments of enuresis in childhood are recommended.
mesh_terms: D000639:Amitriptyline / Q000037:antagonists & inhibitors / Q000506:poisoning*; D000931:Antidotes / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005751:Gastric Lavage; D006801:Humans; D007099:Imipramine / Q000037:antagonists & inhibitors / Q000506:poisoning*
chemical_list: D000931:Antidotes; D000639:Amitriptyline; D007099:Imipramine
vernacular_title: Intoxikation mit Amitriptylin und Imipramin.