Citrate induced hypocalcaemia during cell separation.
The value of calcium addition during cell-separation by the Haemonetics Model 30 has been investigated in two patient groups. Where citrated plasma was used as the replacement fluid the addition of calcium abolished clinical symptoms and reduced the degree of citrate induced hypocalcaemia. When Plasma Protein Fraction was used as the replacement fluid, calcium addition was not necessary as clinical symptoms and significant hypocalcaemia did not occur.
D002118:Calcium / Q000627:therapeutic use*; D002951:Citrates / Q000009:adverse effects*; D004899:Erythroblastosis, Fetal / Q000517:prevention & control; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000139:chemically induced / Q000517:prevention & control*; D010956:Plasmapheresis; D011247:Pregnancy
D002951:Citrates; D002118:Calcium