[Lipids bound with blood plasma proteins in normal state and in experimental rachitis].
The lipid composition of transport and specific proteins was studied in normal state and with experimental rachitis. The amount of phospholipids in blood plasma proteins control animals is established to decrease as follows: albumins, immunoglobulins, alpha, beta-globulins, fibrinogen. The bulk of cholesterol and its ethers, lanosterol and squalenepare bound with albumins and alpha-, beta-globulins. With D-hydrovitaminosis in albumin and alpha-, beta-globulin fractions, the content of phospholipids, cholesterol, lanosterol and squalene in comparison with fibrinogen lowers considerably. An increase in the content of etherified cholesterol is characteristic of all protein fractions under conditions of this pathology. The value of the cholesterol: phospholipids molar ration with D-hypovitaminosis decreases for albumins and alpha-, beta-globulins and increases for immunoglobulins and fibrinogen. As compared to other proteins of blood plasma, with D-hypovitaminosis immunoglobulins are mostly enriched with lipids.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D008055:Lipids / Q000097:blood*; D010743:Phospholipids / Q000097:blood; D011485:Protein Binding; D051381:Rats; D012279:Rickets / Q000097:blood*; D012709:Serum Albumin / Q000378:metabolism; D012712:Serum Globulins / Q000378:metabolism
D001798:Blood Proteins; D008055:Lipids; D010743:Phospholipids; D012709:Serum Albumin; D012712:Serum Globulins; D002784:Cholesterol
Lipidy, sviazannye s belkami plazmy krovi, v norme i pri eksperimental'nom rakhite.