title: A note on gene frequency estimation with misclassification present.
abstract: A genetic model is presented that allows for the maximum likelihood estimation of gene frequencies for simple Mendelian inheritance when specific patterns of misclassification are present. Formulas for the variance of these estimates are also given along with an example of application.
mesh_terms: D000483:Alleles; D005260:Female; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D006720:Homozygote; D006801:Humans; D010641:Phenotype; D013223:Statistics as Topic
chemical_list: D005954:Glucosephosphate Dehydrogenase