title: Antipyrine metabolism in man: simultaneous determination of norantipyrine and 4-hydroxyantipyrine in urine by gas chromatography.
abstract: A gas chromatographic method was developed to determine metabolites of antipyrine, norantipyhis method requires no derivatization and has ample sensitivity to determine these metabolites in urine after ingestion of antipyrine, a compound widely used as a hepatic probe of drug oxidation.
mesh_terms: D000328:Adult; D000983:Antipyrine / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000652:urine; D001711:Biotransformation; D002849:Chromatography, Gas; D003640:Dealkylation; D000077553:Edaravone; D006801:Humans; D006868:Hydrolysis; D006900:Hydroxylation; D008297:Male; D008875:Middle Aged
chemical_list: C007983:4-hydroxyantipyrine; D000077553:Edaravone; D000983:Antipyrine