A mortality analysis of employees engaged in the manufacture of 2,4,5-trichlorophenoxyacetic acid.
There have been few published reports regarding surveillance of individuals occupationally exposed to 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). The present study examined the mortality experience of 204 persons exposed to 2,4,5-T during its manufacture from 1950 to 1971. Length of employment in job assignments within the 2,4,5-T process area ranged from less than one year to a maximum of approximately ten years. Efforts to minimize 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) contamination of the product resulted in nondetectable concentrations using a method of detection developed in 1966 that was sensitive to 1 part per million. Within the scope of this mortality survey, no adverse effects were observed with respect to occupational exposure to 2,4,5-T or its feedstock, 2,4,5-trichlorophenol.
D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000633:toxicity*; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000401:mortality; D002617:Chemical Industry; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008824:Michigan; D009369:Neoplasms / Q000139:chemically induced* / Q000401:mortality; D009784:Occupational Diseases / Q000139:chemically induced*
D015085:2,4,5-Trichlorophenoxyacetic Acid