title: [Parameters of polynuclear cell activity in torpid and latent recurrent rheumocarditis in the process of treatment with a high-protein diet and drug preparations].
abstract: The in vitro test of direct granulation of basophils affected by specific antigens (cardial tissue, acid-soluble fraction of collagen, streptococcal allergens) was investigated in the course of treating 41 patients (29 women and 12 men aged from 20 to 50 years) suffering from a little active rheumatic fever. The patients received a complex of therapeutic measures including high-protein diet (130-140 g protein) and drugs (1.5-2.0 g acetylsalicylic acid and 15 mg of prednisolone a day). As a result of the treatment all the patients improved and demonstrated pain relief in the heart region, reduced palpitation, abatement of general weakness and fatigue. At the same time there was a decrease in the reactivity of basophilic leukocytes, shown by less number of degranulated cells in vitro, activated with specific antigens.
mesh_terms: D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D001491:Basophils / Q000276:immunology; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D012214:Rheumatic Heart Disease / Q000276:immunology* / Q000628:therapy
chemical_list: D004044:Dietary Proteins; D011239:Prednisolone; D001241:Aspirin
vernacular_title: Nekotorye parametry aktivnosti polinuklearov u bol'nykh vialo i latentno tekushchim vozvratnym revmokarditom v protsesse lecheniia vysokobelkovoĭ dietoĭ i medikamentoznymi preparatami.