Induction of labour with oral prostaglandin E2: a Canadian multicentre study.
Prostaglandin E2 (PgE2) tablets were administered orally for the induction of labour at or near term to 680 patients. Successful vaginal delivery occurred in 81.8% of patients with a mean total dose of 3.7 mg and a mean induction-delivery interval of 7.1 hours. PgE2 was most efficacious in parous patients and in those with high Bishop scores. The most common maternal side-effects were gastro-intestinal in nature and uterine hypertonus was observed in six patients. Foetal heart rate changes occurred in fifty patients.
D000293:Adolescent; D000328:Adult; D002170:Canada; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007751:Labor, Induced; D008875:Middle Aged; D011247:Pregnancy; D011458:Prostaglandins E / Q000009:adverse effects / Q000627:therapeutic use*
D011458:Prostaglandins E