Renal polycystosis in the rat induced by prednisolone tertiary butyl acetate.
A single i.m. injection of 66 mg/kg prednisolone tertiary butyl acetate given on the 1st day of life produced glomerular degeneration and collecting duct and proximal tubule cysts in rat kidneys. There was evidence of delayed nephrogenesis leading to persistance of the neogenic zone.
D000818:Animals; D004195:Disease Models, Animal; D007690:Polycystic Kidney Diseases / Q000139:chemically induced / Q000473:pathology*; D011239:Prednisolone / Q000031:analogs & derivatives; D051381:Rats
C009021:prednisolone tebutate; D011239:Prednisolone