Effect of fasting and sex steroids on arachidonate uptake into rat platelets.
Comparison of uptake between fed and fasted animals indicates that short-term changes in nutritional states significantly affects AA uptake and the effect of testosterone upon uptake. Consequently, the tradition of fasting animals prior to experimental manipulation may obscure not only sex differences but other factors as well. Clearly the experimental data obtained on fasted animals may not be a good model for Western man.
D000818:Animals; D001095:Arachidonic Acids / Q000097:blood*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D004958:Estradiol / Q000494:pharmacology*; D005215:Fasting; D006728:Hormones / Q000494:pharmacology; D008297:Male; D009829:Oleic Acids / Q000097:blood; D051381:Rats; D012737:Sex Factors; D013739:Testosterone / Q000494:pharmacology*
D001095:Arachidonic Acids; D006728:Hormones; D009829:Oleic Acids; D013739:Testosterone; D004958:Estradiol