A 45,X male with translocation of euchromatic Y chromosome material.
A phenotypically normal 32-year-old male with azoospermia was found to have a 45,X karyotype with presence of excess euchromatic material on 14p. The parent's karyotypes are normal. This observation is interpreted as a Y/14 translocation with loss of the heterochromatic Y chromosome material.
D000328:Adult; D002901:Chromosomes, Human, 13-15; D006570:Heterochromatin; D006801:Humans; D008297:Male; D009697:Nucleolus Organizer Region; D009845:Oligospermia / Q000235:genetics; D010641:Phenotype; D012730:Sex Chromosomes; D014178:Translocation, Genetic; D014424:Turner Syndrome / Q000235:genetics*; D014998:Y Chromosome
D006570:Heterochromatin