Corticosterone catabolism by mouse liver: interactions between genotype and diet.
Corticosterone reduction was greater in liver homogenates from C57BL/10ScSn mice than in homogenates from DBA/2J mice. The reactions were stimulated to the same extent by the addition of an NADPH-generating system when the mice had been on a 4% fat diet. When the mice had been on a fat-free diet for 3 days, the generating system produced a much greater effect on homogenates from DBA mice. C57BL/Tb mice resembled C67BL/10ScSn mice with CBA/FaCam mice were similar to DBA/2J mice.
D000818:Animals; D003345:Corticosterone / Q000378:metabolism*; D004041:Dietary Fats / Q000008:administration & dosage; D005838:Genotype; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009249:NADP / Q000494:pharmacology; D013045:Species Specificity
D004041:Dietary Fats; D009249:NADP; D003345:Corticosterone