[Role of food and other modifying factors in the development of stomach cancer].
The effect of the alimentary, nervous, hormonal and drug factors on gastric secretion and resistance to the action of chemical cancerogenic substances was studied in four experiments. It was established that all these factors affecting gastric secretion for a long time, exert through it an effect on gastric resistance to the action of chemical cancerogenic substances. It was shown as well that gastric resistance to cancerogenic effects correlated directly with the rate of gastric secretion. The higher it was the stronger resistance the stomach exhibited to the action of chemical cancerogenic substances. Decreased gastric secretion is a factor predisposing to cancer of the stomach rather than an obligatory precancerous condition.
D000126:Achlorhydria / Q000150:complications; D000818:Animals; D005506:Food Contamination; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D011083:Polycyclic Compounds / Q000009:adverse effects; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013270:Stomach / Q000187:drug effects; D013274:Stomach Neoplasms / Q000209:etiology*
D011083:Polycyclic Compounds
Rol' pishchevykh i drugikh modifitsiruiushchikh faktorov v razvitii raka zheludka.