title: Mania occurring during treatment for depersonalization: a report of two cases.
abstract: Severe depersonalization at times constitutes a chronic and disabling syndrome for which there is no generally established etiology or treatment. Two cases in which young female patients with severe depersonalization became floridly manic in response to stimulant and antidepressant drug treatment are reported, and the clinical and theoretical implications of these phenomena are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects; D001714:Bipolar Disorder / Q000139:chemically induced / Q000209:etiology*; D003861:Depersonalization / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008694:Methamphetamine / Q000009:adverse effects; D011605:Psychoses, Substance-Induced / Q000209:etiology
chemical_list: D000928:Antidepressive Agents; D008694:Methamphetamine