A method for the estimation of the activity of the inhibitor of the first component of complement.
The activated first component of complement (CI) possesses an esterase activity in vitro which will hydrolyse an ester of tyrosine to release H+. The activity of the serum inhibitor of C1 esterase may be measured by monitoring its ability to prevent H+ release under standard conditions. This paper describes a method of measuring such activity, monitoring H+ release by the use of either an acid base indicator of pH meter.
D003124:Colorimetry / Q000379:methods; D003174:Complement C1 Inactivator Proteins / Q000097:blood*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008722:Methods
D003174:Complement C1 Inactivator Proteins