title: The radiolysis of tryptophan and leucine with 32P beta-radiation.
abstract: We have extended earlier experiments on the radiolysis of DL-tryptophan using 32 p beta-radiation to longer reaction times, observing complete destruction of the tryptophan by secondary, non-radiolytic processes. We have also undertaken the irradiation of DL-leucine with 32 P beta's at -196 degrees, achieving radiolyses to the extents of ca. 20-30%, but observing no concomittant asymmetric bias. The implications of these observations are discussed with regard to the Vester-Ulbricht mechanism for the origin of optical activity.
mesh_terms: D004307:Dose-Response Relationship, Radiation; D007930:Leucine / Q000528:radiation effects*; D010761:Phosphorus Radioisotopes; D013237:Stereoisomerism; D014364:Tryptophan / Q000528:radiation effects*
chemical_list: D010761:Phosphorus Radioisotopes; D014364:Tryptophan; D007930:Leucine