HbE-beta-thalassemia associated with G6PD deficiency.
HbE, beta thalassemia, and G6PD deficiency were demonstrated in a 6-year-old Mexican-American child with anemia, jaundice, and delayed growth. The father was heterozygous for HbE, and the mother for beta-thalassemia and G6PD deficiency. The association of these three diseases should be included in the differential diagnosis of anemia in childhood, particularly after the recent influx of people form Southeast Asia into the United States.
D002648:Child; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood* / Q000150:complications; D006446:Hemoglobin E; D006455:Hemoglobins, Abnormal; D006801:Humans; D008297:Male; D013789:Thalassemia / Q000097:blood* / Q000150:complications
D006455:Hemoglobins, Abnormal; D006446:Hemoglobin E