title: Marked elevation in serum alkaline phosphatase activity as a manifestation of systemic infection.
abstract: Jaundice of severe bacterial infection is well known. Marked elevation of the alkaline phosphatase has not previously been emphasized as a manifestation of severe bacterial infection. We report 4 patients with bacterial infection manifested chemically by a markedly elevated serum alkaline phosphatase and a minimally elevated serum bilirubin.
mesh_terms: D000038:Abscess / Q000503:physiopathology; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D001064:Appendicitis / Q000503:physiopathology; D001424:Bacterial Infections / Q000097:blood / Q000503:physiopathology*; D004239:Diverticulitis, Colonic / Q000503:physiopathology; D004653:Empyema / Q000503:physiopathology; D006615:Hip; D006801:Humans; D007877:Legionnaires' Disease / Q000503:physiopathology; D008099:Liver / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged
chemical_list: D000469:Alkaline Phosphatase