title: The concept of adaptive differentiation: relevance to MHC polymorphism, self-recognition, and leukemogenesis.
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D006168:Guinea Pigs; D007938:Leukemia / Q000276:immunology; D008214:Lymphocytes / Q000166:cytology*; D008285:Major Histocompatibility Complex; D051379:Mice; D011110:Polymorphism, Genetic