Effects of administration of cannabis resin during pregnancy on emotionality and learning in rats' offspring.
Injection of cannabis resin as a saline-Tween 80 solution to pregnant rats resulted in pups having lower body weight, higher emotionality, poorer learning capacity, and paradoxically higher brain weight and DNA content. The cannabis appeared directly to have caused the inferior growth rate of the pups which in turn affected emotionality and learning.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D001921:Brain / Q000033:anatomy & histology; D002186:Cannabinoids / Q000494:pharmacology*; D004247:DNA / Q000378:metabolism; D004193:Discrimination Learning / Q000187:drug effects*; D004644:Emotions / Q000187:drug effects*; D005260:Female; D009048:Motor Skills / Q000187:drug effects*; D009929:Organ Size / Q000187:drug effects; D011247:Pregnancy; D051381:Rats
D002186:Cannabinoids; D004247:DNA