title: Survey on haemoglobin variants, beta-thalassaemia, glucose-6-phosphate dehydrogenase deficiency and haptoglobin types in Turkish people living in Manavgat, Serik and Boztepe (Antalya).
abstract: 135 Turks living in the vicinity of Antalya, a Turkish city on the Mediterranean coast, were studied for haemoglobin variants, beta-thalassaemia G-6-PD deficiency and haptoglobin types. The incidence of Hb-S was 2.3%. 8 beta-thalassaemic individuals with increased Hb-A2 and patient with 1 sickle cell-beta2-thalassaemia disease were found. The incidence of beta-thalassaemia with increased Hb-A2 was 6.7% and that of G-6-PD deficiency was 5.4%. The distribution of haptoglobin types in these people was very similar to that found in Turkish people in general; the only exception was the presence of Hp O in 2 individuals without haemolytic disorder. Gene frequencies of Hp1 and Hp2 were 0.26 and 0.7p4, respectively.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood* / Q000235:genetics*; D006242:Haptoglobins / Q000235:genetics*; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013789:Thalassemia / Q000097:blood / Q000235:genetics*; D014421:Turkey
chemical_list: D006242:Haptoglobins; D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal