Inhibition of mitochondrial carnitine palmitoyl transferase by 2-tetradecylglycidic acid (McN-3802) (preliminary communication).
D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D002334:Carnitine O-Palmitoyltransferase / Q000037:antagonists & inhibitors*; D003065:Coenzyme A / Q000494:pharmacology; D003956:Dialysis; D004852:Epoxy Compounds / Q000494:pharmacology*; D004988:Ethers, Cyclic / Q000494:pharmacology*; D005227:Fatty Acids / Q000378:metabolism; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D007700:Kinetics; D008930:Mitochondria, Liver / Q000201:enzymology*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D011422:Propionates / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D005227:Fatty Acids; D007004:Hypoglycemic Agents; D011422:Propionates; D000255:Adenosine Triphosphate; D000217:Acyltransferases; D002334:Carnitine O-Palmitoyltransferase; C021756:2-tetradecylglycidic acid; D003065:Coenzyme A