Binding of [3H]GABA and [3H]muscimol to subcellular particles of a neurone-enriched culture of mouse brain.
Binding of [3H]GABA and [3H]muscimol, indicative of GABA-receptors, has been demonstrated in a neurone-enriched culture of embryonic mouse brain using a ligand-binding technique. Evidence is provided for the existence of different populations of GABA-receptors.
D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000378:metabolism*; D002478:Cells, Cultured; D004622:Embryo, Mammalian; D007700:Kinetics; D008024:Ligands; D051379:Mice; D009118:Muscimol / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D010080:Oxazoles / Q000378:metabolism*; D011485:Protein Binding; D011955:Receptors, Drug / Q000378:metabolism*; D014316:Tritium; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D008024:Ligands; D010080:Oxazoles; D011955:Receptors, Drug; D014316:Tritium; D009118:Muscimol; D005680:gamma-Aminobutyric Acid