Effect of ethanol and nicotine in the pregnant rat.
Treatment of pregnant Sprague-Dawley rats on day 9 of gestation with both ethanol (0.02 ml/gm of a 12.5% or 25% solution, i.p.) and nicotine (5 mg/kg, s.c.) resulted in no significant adverse effects on embryonic development and fetal viability.
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000818:Animals; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D005327:Fetal Resorption / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D009538:Nicotine / Q000633:toxicity*; D010920:Placenta / Q000187:drug effects; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats; D012098:Reproduction / Q000187:drug effects
D000431:Ethanol; D009538:Nicotine