title: Juvenile fibromatosis of the periorbital region and eyelid. A clinicopathologic study of six cases.
abstract: Six cases of juvenile fibromatosis of the periorbital region and eyelid were studied. The median age of the patients was 8 years (range, 1 to 11 years). A definite propensity for involvement of the infraorbital region and lower eyelid was observed. THREE TUMORS EXHIBITED A PROMINENT LOBULAR PATTERN AND WERE ADHERENT TO THE PERIOSTEUM. The main entities in the differential diagnosis included leiomyoma, neurofibroma, and well-differentiated fibrosarcoma. Two of six tumors recurred locally but did not metastasize. Electron microscopic studies disclosed that the spindle-shaped tumor cells exhibited features of fibroblasts. It appears that conservative treatment (ie, local excision) is adequate.
mesh_terms: D002648:Child; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005350:Fibroma / Q000473:pathology* / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local; D009918:Orbital Neoplasms / Q000473:pathology* / Q000628:therapy