[Possibility of determination of the type of cardiomyocyte death with the aid of ultrastructural analysis].
An attempt was made to determine the ultrastructure of those types of cell death which may occur experimentally only during life and to compare them with the findings obtained from the autopsy materials of the myocardium of persons dying suddenly or from acute myocardial infarction. Three ultrastructural types of cellular death were determined in the experimental and autopsy material: primary-ischemic, primary-calcium, and secondary-calcium types. The ultrastructural pattern of some irreversible changes found in the autopsy material may be used for retrospective judgement on the mechanisms of cell death. The results obtained do not completely solve the problem of interpretation of ultrastructural findings in examinations of human postmortem materials although open some approaches for using electron microscopy in addition to the main sources of information in the study of sudden death.
D000208:Acute Disease; D000818:Animals; D001344:Autopsy; D002470:Cell Survival; D003645:Death, Sudden / Q000473:pathology; D004285:Dogs; D006801:Humans; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000648:ultrastructure*; D009203:Myocardial Infarction / Q000473:pathology; D009206:Myocardium / Q000648:ultrastructure*; D011180:Postmortem Changes
O vozmozhnosti opredeleniia tipa kletochnoĭ smerti kardiomiotsitov pri pomoshchi ul'trastrukturnogo analiza.