title: Beta-chain contact sites in the haemoglobin S polymer.
abstract: The amino acid residues involved in the areas of contact that stabilise the haemoglobin S polymer fibre seem to be the same ones that stabilise the basic unit of the deoxyhaemoglobin S crystal: the Wishner-Love double strand. The haemoglobin S fibre is probably formed by a unique packing of these double strands.
mesh_terms: D001665:Binding Sites; D003460:Crystallization; D006451:Hemoglobin, Sickle / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000235:genetics; D006801:Humans; D009154:Mutation; D011485:Protein Binding
chemical_list: D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal