The synthesis and activity of cis- and trans-2-(aminomethyl) cyclopropanecarboxylic acid as conformationally restricted analogues of GABA.
D000612:4-Aminobutyrate Transaminase / Q000378:metabolism; D000596:Amino Acids / Q000138:chemical synthesis / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002415:Cats; D003521:Cyclopropanes / Q000138:chemical synthesis / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D051381:Rats; D013116:Spinal Cord / Q000187:drug effects / Q000502:physiology; D013329:Structure-Activity Relationship; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D000596:Amino Acids; D003521:Cyclopropanes; D005680:gamma-Aminobutyric Acid; D000612:4-Aminobutyrate Transaminase