title: The evolution of the protein synthesis system, II. From chemical evolution to biological evolution.
abstract: The sequence of events previously proposed for modern protein synthesis is reviewed. It begins with an abiological synthesis of a template, and evolves through two model autocatalytic systems to a primitive cell that has a rudimentary biological protein synthesis system. A possible scheme for the origin of tRNA's is described so as to fill the gap between the model and the modern system. Fragments of genes that existed in and around the primitive system are proposed to be precursors of tRNA's. Since these fragments must have been undesirable components for the system, the origin and evolution of tRNA's may be regarded as an excellent answer by the primitive system to adverse circumstances.
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D005796:Genes; D005815:Genetic Code; D006801:Humans; D009690:Nucleic Acid Conformation; D000069497:Origin of Life; D014176:Protein Biosynthesis; D012343:RNA, Transfer; D013698:Templates, Genetic; D014158:Transcription, Genetic
chemical_list: D012343:RNA, Transfer