title: The effect of dietary fat on the fatty acid composition of lipids secreted in rats' milk.
abstract: During pregnancy and lactation, female rats were fed diets containing either 28% partially hydrogenated marine oil (28MO), 2% arachis oil (2AO), or no fat (FF). Milk lipid composition was examined by gas chromatographic analysis of the gastric content of 10-day-old suckling pups. An increase to 45% in the milk content of long chain monoenoic acids, 18:1, 20:1 and 22:1, reflects the fatty acid composition of the marine oil. Milk fatty acids of medium chain length comprised 6%, 31% and 24% of total fatty acids in the (28MO), (2AO) and (FF) groups, respectively, suggesting that a high-fat diet (28MO) inhibits the lipid synthetic activity of mammary glands. The amount of dienoic C18-acids (6%) in the group fed (28MO) containing no essential fatty acids (EFA) was similar to the amount of 18:2 in the group receiving a low-fat, EFA-rich diet (2AO). However, only half the dienoic acid from the milk of the (28MO)-fed animals was linoleic acid, which was most likely mobilized from fat depots.
mesh_terms: D000818:Animals; D004041:Dietary Fats / Q000494:pharmacology*; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D007774:Lactation; D008055:Lipids / Q000032:analysis*; D008892:Milk / Q000032:analysis / Q000187:drug effects*; D011247:Pregnancy; D051381:Rats
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D008055:Lipids