Metabolic activation of a mutagen, 2-amino-6-methyldipyrido-[1,2-a:3',2'-d]imidazole. Identification of 2-hydroxyamino-6-methyldipyrido [1,2-a:3',2'-d]imidazole and its reaction with DNA.
D000818:Animals; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D004247:DNA; D007093:Imidazoles / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism*; D009153:Mutagens; D011725:Pyridines / Q000378:metabolism*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D013950:Thymus Gland
D007093:Imidazoles; D009153:Mutagens; D011725:Pyridines; C023785:2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole; C023786:2-hydroxyamino-6-methyldipyrido(1,2-a-3',2'-d)imidazole; D004247:DNA