The preparation and stability of radioiodinated antipyrine for use in local blood flow determinations.
The accurate assessment of local blood flow by recording the washout of a deposit of radiolabelled 4-iodoantipyrine (4-IAP) requires the use of a stable radiopharmaceutical. This communication shows that it is possible to produce a 125I and 131I-4-IAP compound which fulfills this requirement under simulated conditions of use.
D000983:Antipyrine / Q000032:analysis; D004355:Drug Stability; D006801:Humans; D007454:Iodides / Q000032:analysis; D007457:Iodine Radioisotopes; D007553:Isotope Labeling; D012039:Regional Blood Flow
D007454:Iodides; D007457:Iodine Radioisotopes; D000983:Antipyrine