Analysis of benzimidazoles in body fluids by high-performance liquid chromatography.
A simple assay for benzimidazole in plasma and GI fluids using high-performance liquid chromatography was developed. The benzimidazoles were extracted using ether and were chromatographed with methanol-ammonium carbonate mixtures as the eluting solvents. Benzimidazole was detectable in 4 ml of plasma or GI fluid to a limit of 20 ng/ml.
D000818:Animals; D001562:Benzimidazoles / Q000032:analysis*; D001826:Body Fluids / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005273:Fenbendazole / Q000032:analysis; D012756:Sheep
D001562:Benzimidazoles; D005273:Fenbendazole