title: Relationship between single- and multi-locus measures of gene diversity in a subdivided population.
abstract: A mathematical relationship between the coefficient of gene diversity as derived from average single locus statistics and Smouse and Spielman's multi-locus measure is established under the assumption of linkage equilibrium in a substructured population. A formula for estimating the average time of split of subpopulations from such gene diversity is also derived for the multi-locus criterion. Unlike the estimate derived for single-locus criterion, this estimate does not explicitely depend on the number of subpopulations. The method is illustrated with data on allozyme studies from the South American Indian populations.
mesh_terms: D000483:Alleles; D001938:Brazil; D002874:Chromosome Mapping; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D007199:Indians, South American