title: Determination of erythrocyte uroporphyrinogen I synthetase activity in chronic renal failure.
abstract: To obtain some information on porphyrin metabolism in uraemic patients, the activity of erythrocyte uroporphyrinogen I synthetase was measured in patients with chronic renal failure. The results indicate a decreased enzymatic activity which is not due to urea interference, in the hemolysates of these patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000642:Ammonia-Lyases / Q000032:analysis*; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D011163:Hydroxymethylbilane Synthase / Q000032:analysis*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000201:enzymology*; D008297:Male; D008875:Middle Aged
chemical_list: D011163:Hydroxymethylbilane Synthase; D000642:Ammonia-Lyases