title: Microcalorimetric measurements of heat production in platelets of patients with prosthetic heart valves.
abstract: The heat production in resting platelets of 12 patients with prosthetic heart valves was found to be significantly decreased (p less than 0.005), P = 49 +/- 9 fW/cell. In a matched control group of eight patients with heart valve disease, the corresponding heat production value in resting platelets was P = 65 +/- 11 fW/cell. The present results indicate that the overall metabolic activity in platelets of patients with prosthetic heart valves is abnormally low.
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000378:metabolism*; D002151:Calorimetry / Q000379:methods; D005260:Female; D006349:Heart Valve Diseases / Q000097:blood*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000378:metabolism; D013923:Thromboembolism / Q000209:etiology