Lower esophageal strictures, benign or malignant?
In a retrospective study of 93 patients with benign peptic strictures, and 73 patients with malignancy of the lower third of the esophagus, 93% of benign strictures were associated with a hiatal hernia, and 4% without. In malignancy the majority were without hernia. The results provide a statistical basis for strong suspicion of malignancy in a lower esophageal stricture not accompanied by a hiatal hernia.
D001706:Biopsy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D004940:Esophageal Stenosis / Q000150:complications* / Q000000981:diagnostic imaging; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006548:Hernia, Diaphragmatic / Q000150:complications*; D006551:Hernia, Hiatal / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011859:Radiography; D012189:Retrospective Studies