[Changes in bile acid metabolism in cholestasis].
The metabolism of bile acids is grossly disturbed under the conditions of cholestasis. Atypical bile acids are formed, which are mainly excreted into the urine. With regard to the origin of these atypical bile acids analyses of human meconium support the hypothesis that bile acid metabolism in cholestasis reverts to a fetal biosynthetic pattern. Problems may arise in cholestatic liver disease, if the elimination of atypical bile acids is impaired.
D001647:Bile Acids and Salts / Q000378:metabolism* / Q000652:urine; D002779:Cholestasis / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000378:metabolism
D001647:Bile Acids and Salts
Veräunderungen des Gallensäuren-Stoffwechsels bei Cholestase.