Proposed mechanism for colchicine poisoning of microtubules reassembled in vitro from Strongylocentrotus purpuratus sperm tail outer doublet tubulin.
D000818:Animals; D003078:Colchicine / Q000494:pharmacology*; D006160:Guanosine Triphosphate / Q000378:metabolism; D007700:Kinetics; D046911:Macromolecular Substances; D008297:Male; D008870:Microtubules / Q000187:drug effects / Q000648:ultrastructure*; D012617:Sea Urchins; D013094:Spermatozoa / Q000187:drug effects / Q000648:ultrastructure*; D014404:Tubulin / Q000378:metabolism*
D046911:Macromolecular Substances; D014404:Tubulin; D006160:Guanosine Triphosphate; D003078:Colchicine