title: [Study of interneuronal cortical connections using kainic acid injections].
abstract: The changes that occurred in the cat cerebral cortex were studied days 1, 3, 7 and 14 following administration of 0.2% kainic acid. Kainic acid was shown to produce a local destruction of neuronal cell bodies and their dendrites and to spare the afferent fibers that pass through or terminate in the injected area. These effects were demonstrated with using the methods of Golgi and Golgi-Kopsch as well as during the administration of horseradish peroxidase after kainic acid injection into the cerebral cortex. The 3-day period following the injection is the most optimal for studies into interneuronal relations. The experiments revealed pericellular baskets formed by afferents around the pyramidal cells.
mesh_terms: D000818:Animals; D001931:Brain Mapping / Q000379:methods; D002415:Cats; D002540:Cerebral Cortex / Q000033:anatomy & histology* / Q000166:cytology; D007608:Kainic Acid; D009434:Neural Pathways / Q000033:anatomy & histology; D009474:Neurons / Q000166:cytology
chemical_list: D007608:Kainic Acid
vernacular_title: Izuchenie mezhneĭronnykh korkovykh sviazeĭ s pomoshch'iu in''ektsii kainovoĭ kisloty.