title: Potential anticancer agents. XVI. Isolation of bicyclofarnesane sesquiterpenoids from Capsicodendron dinisii.
abstract: The cytotoxic drimane derivatives cinnamodial (1), capsicodendrin (2), a partially characterized tetramer of 1, and cinnamosmolide (3) were obtained from Capsicodendron dinisii (Canellaceae). A new compound, 6 beta-acetoxyisodrimenin (4) and ugandensolide (5) and futronolide (6) were also isolated, but were not cytotoxic.
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D007941:Leukemia P388 / Q000188:drug therapy; D009303:Nasopharyngeal Neoplasms; D009374:Neoplasms, Experimental; D010946:Plants, Medicinal / Q000032:analysis*; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D012717:Sesquiterpenes