[Lincomycin concentration in the blood and tissues when administered by electrophoresis in children with acute and chronic hematogenic osteomyelitis].
Twenty five children suffering from acute and chronic hematogenic osteomyelitis were subjected to lincomycin therapy in addition to surgical and general tonic treatment. The antibiotic was administered by means of electrophoresis in 15 children and by means of electrophoresis together with intramuscular injections in 10 children. It was found that administration of the drug by means of electrophoresis 1 hour after its intramuscular injection provided the highest lincomycin levels in the bone cavity favourable for the disease treatment.
D000293:Adolescent; D001842:Bone and Bones / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007478:Iontophoresis; D008034:Lincomycin / Q000008:administration & dosage / Q000378:metabolism*; D010019:Osteomyelitis / Q000188:drug therapy / Q000378:metabolism*; D013997:Time Factors; D014018:Tissue Distribution
D008034:Lincomycin
Kontsentratsiia linkomitsina v krovi i tkaniakh pri vvedenii ego metodom élektroforeza u deteĭ s ostrym i khronicheskim gematogennym osteomielitom.