Kinetics of suicide substrates.
When suicide substrates inactivate enzymes during catalysis, formation of product and inactivation of enzyme proceed concurrently. The steady-state hypothesis is applicable when catalytic quantities of enzyme are used. Equations for the rate of inactivation have been derived and integrated to obtain equations describing progress curves.
D004791:Enzyme Inhibitors; D007700:Kinetics; D008956:Models, Chemical
D004791:Enzyme Inhibitors