Changes of fucose content in the surface glycoproteins of macrophages induced by golden hamster transplantable melanomas.
The influence of two kinds of transplantable melanomas on the content of fucose in the surface glycoproteins of hamster peritoneal macrophages was studied. An increase in the content of fucose, more prominent in surface material of macrophages from animals with melanotic melanoma was found. It has been suggested that this phenomenon is connected with the neoplastic process, and that the different susceptibility of the macrophages from experimental animals to macrophage inhibitory factor (MIF) is related to changes in the content of fucose in the surface glycoproteins.
D000818:Animals; D006224:Cricetinae; D005643:Fucose / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis*; D008264:Macrophages / Q000032:analysis*; D008297:Male; D008545:Melanoma / Q000378:metabolism* / Q000473:pathology; D008565:Membrane Proteins / Q000032:analysis*; D008647:Mesocricetus; D009368:Neoplasm Transplantation; D014184:Transplantation, Homologous
D006023:Glycoproteins; D008565:Membrane Proteins; D005643:Fucose