title: Partial recovery of the stimulatory oestrogen feedback action on LH release during late lactation in the pig.
abstract: The functioning of the stimulatory oestrogen feedback mechanism during lactational anoestrus of the sow was evaluated by determining the LH response to a single i.m. injection of oestradiol benzoate. Oestradiol-17 beta and progesterone levels were also measured following treatment and following weaning. On Day 5 of lactation there was no LH response to oestradiol benzoate but on Day 35 of lactation a small but significant (P less than or equal to 0.05) increase in plasma LH occurred, and this was followed by a rise in plasma progesterone in 4 out of 9 animals 8 or 13 days later. It is concluded that blockade of the stimulatory oestrogen feedback mechanism is one cause of lactational anoestrus in the sow.
mesh_terms: D000818:Animals; D004958:Estradiol / Q000097:blood / Q000494:pharmacology*; D005246:Feedback; D005260:Female; D007774:Lactation; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D013552:Swine
chemical_list: D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone