Postoperative pain relief using epidural morphine.
In postoperative prostatectomy patients, morphine 2 mg in 10 ml 0.9% saline was given epidurally for pain relief and its effectiveness compared with bupivacaine. The duration of analgesia with morphine was approximately double that with bupivacaine. Significant hypotension occurred in approximately 5% of the patients receiving bupivacaine, but was not seen following morphine. These seem to be important advantages in the use of morphine by this route.
D000767:Anesthesia, Epidural; D001794:Blood Pressure / Q000187:drug effects; D002045:Bupivacaine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009020:Morphine / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy*; D011468:Prostatectomy; D013997:Time Factors
D009020:Morphine; D002045:Bupivacaine