title: Genetic and hormonal aspects of male facilitation of PMSG-induced ovulation in immature mice.
abstract: Immature female mice of the SWR/J and C3H/Ibg strains pretreated with PMSG showed higher incidence of ovulation when exposed to males of the same strain than did those kept isolated after weaning. Females of the C57BL/6Ibg strain were not affected. The numbers of eggs ovulated were also greater in SWR and C3H females than in the C57 females. When SWR/J females were killed after exposure to males for 2, 4 or 6 h, there was a 6-fold increase in LH levels at 6 h compared to values in isolated controls. It is suggested that adult male mice of some strains provide a stimulus which promotes release of LH in the immature female.
mesh_terms: D000818:Animals; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D010060:Ovulation / Q000187:drug effects*; D012726:Sexual Behavior, Animal; D012741:Sexual Maturation; D012932:Social Facilitation
chemical_list: D006064:Gonadotropins, Equine; D007986:Luteinizing Hormone