title: [Extension of traumatic mucosal changes and their relevance in reconstructive surgery in laryngeal and tracheal stenoses following long-term intubation (author's transl)].
abstract: Serial light and electron microscopy studies done to determine the earliest that significant mucosal changes occur after translaryngeal intratracheal long-term intubation show that, as well as a penetrating lesion at the site of the pressure effect of the tube, there is a mucosal injury which extends up and down away from the focus of the lesion. This is a consequence of trauma, and away from the site of the trauma, three differing zones of mucosal change can be identified. Cognisance of this explains the healing problems that can occur following reconstructive surgery, particularly in the border area between seemingly undamaged tissue and preserved or directly grafted tissue. Instructions in regard to avoiding unsatisfactory surgery is given.
mesh_terms: D000818:Animals; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007820:Laryngeal Mucosa / Q000293:injuries* / Q000648:ultrastructure; D007829:Laryngostenosis / Q000601:surgery; D007830:Larynx / Q000293:injuries*; D011817:Rabbits; D014132:Trachea / Q000293:injuries* / Q000648:ultrastructure; D014135:Tracheal Stenosis / Q000601:surgery
vernacular_title: Die Flächenausdehnung traumatischer Schleimhautveränderungen und ihre Bedeutung für die rekonstruktive Chirurgie bei Kehlkopf- und Trachealstenosen nach Langzeitintubation.