Genetic polymorphism of a serum euglobulin of chickens which binds to antigen-antibody complexes.
Binding of a euglobulin from normal chicken serum to precipitating HSA anti-HSA complexes has been demonstrated. The binding appeared specific for the Fc-fragment of chicken antibody since it was not detected with rabbit Ag-Ab complexes. Two allelic allotypic markers of the euglobulin under genetic control from one locus (E-1) were found in chickens from two inbred strains. E-1 alleles segregated independently from those controlled by the B (major histocompatibility), M-1 and G-1 (Ig allotype) loci. Partially purified E-1 had a sedimentation coefficient of 15.6 S. and beta-globulin electrophoretic mobility.
D000818:Animals; D000936:Antigen-Antibody Complex; D001665:Binding Sites; D011232:Chemical Precipitation; D002645:Chickens; D002847:Chromatography, Agarose; D007126:Immunoglobulin Allotypes / Q000235:genetics; D008074:Lipoproteins; D011110:Polymorphism, Genetic; D011817:Rabbits; D012709:Serum Albumin / Q000276:immunology; D012712:Serum Globulins / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification
D000936:Antigen-Antibody Complex; D007126:Immunoglobulin Allotypes; D008074:Lipoproteins; D012709:Serum Albumin; D012712:Serum Globulins