Factors influencing the inhibitory effect of selenium on mice inoculated with Ehrlich ascites tumor cells.
Selenium, administered to mice with Ehrlich ascites tumors, effectively limited tumor growth. The response was dependent on the chemical form and dose of selenium administered. At the doses administered, there were no detectable adverse effects to the host.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000473:pathology; D002460:Cell Line; D002463:Cell Membrane Permeability; D003553:Cystine / Q000031:analogs & derivatives; D004305:Dose-Response Relationship, Drug; D008297:Male; D051379:Mice; D009368:Neoplasm Transplantation; D012643:Selenium / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D012645:Selenomethionine / Q000008:administration & dosage
D003553:Cystine; D012645:Selenomethionine; D012643:Selenium