Separation of the tumor-associated transplantation antigen (TATA) from the alien H-2k antigens expressed on a methylcholanthrene-induced tumor.
The tumnor-associated transplantation antigen (TATA), alien H-2k antigens and normal H-2d antigens expressed on a methylcholanthrene-induced tumor were monitored during gel filtration and lectin affinity chromatography of detergent-solubilized tumor-cell membranes. TATA was resolved from both the normal and alien H-2 antigens by these techniques. The relationship between histocompatibility antigens and TATA is discussed.
D000818:Animals; D000951:Antigens, Neoplasm / Q000302:isolation & purification*; D002462:Cell Membrane / Q000276:immunology; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D006183:H-2 Antigens / Q000276:immunology / Q000302:isolation & purification*; D006649:Histocompatibility Antigens / Q000276:immunology / Q000302:isolation & purification*; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology*
D000951:Antigens, Neoplasm; D006183:H-2 Antigens; D006649:Histocompatibility Antigens; D008748:Methylcholanthrene