title: Effects of lasalocid (.0125%) in combination with roxarsone on lesion reduction and oocyst suppression in chickens infected with Eimeria tenella field isolates.
abstract: Lasalocid (.0125%) alone and combined with roxarsone (.005%) was evaluated for its effect on lesion reduction and oocyst suppression in thirty-five controlled replicated battery experiments, using in excess of 6200 broiler chickens. The chickens were inoculated with field isolates containing predominantly Eimeria tenella species. Lasalocid (.0125%) used alone exhibited a high degree of anticoccidial activity. Lasalocid (.0125%) fed in combination with roxarsone (.005%) showed, in addition to high anticoccidial activity, a further reduction in gross lesion (P less than .01) and oocyst production (P less than .05) over lassalocid used alone.
mesh_terms: D000818:Animals; D001152:Arsenicals / Q000627:therapeutic use*; D002645:Chickens; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D004359:Drug Therapy, Combination; D004539:Eimeria / Q000187:drug effects; D007832:Lasalocid / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000188:drug therapy*; D012406:Roxarsone / Q000627:therapeutic use*
chemical_list: D001152:Arsenicals; D012406:Roxarsone; D007832:Lasalocid