title: D-Homo isomers of 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione.
abstract: The three most readily accessible D-homo isomers of 17-acetoxy-6-methylpregna-4,6-diene-3,20-dione (Ib) have been prepared and characterized in detail. The 17-keto isomers IIb and IIIb were obtained by base-catalyzed rearrangement of Ia followed by reacetylation, and the 17a-ketone IVb by Lewis-Acid treatment of Ia.
mesh_terms: D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D008535:Megestrol / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D019290:Megestrol Acetate; D008722:Methods; D008968:Molecular Conformation; D013329:Structure-Activity Relationship
chemical_list: D008535:Megestrol; D019290:Megestrol Acetate