Autosomal dominant inheritance of hypercalciuria.
We examined 37 first and second degree relatives of 10 children with hypercalciuria. In 2 families only the index patient was affected, while in 8 others one of the parents was hypercalciuric; in the total of 47 persons examined 23 cases of "idiopathic" hypercalciuria could be identified. None of the subjects was hypercalcemic. The pedigrees suggest autosomal dominant inheritance of the trait.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002118:Calcium / Q000652:urine*; D002128:Calcium Metabolism Disorders / Q000150:complications / Q000235:genetics* / Q000652:urine; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000209:etiology; D008297:Male; D010375:Pedigree
D002118:Calcium