Respiratory vasculitis.
Respiratory vasculitis is characterized by granulomatous changes pathologically. Both upper and lower respiratory tracts may be involved. It is convenient to separate three entities: (1) Wegener's granulomatosis, (2) allergic granulomatosis and angiitis, or Churg-Strauss syndrome, and (3) polymorphic reticulosis/lymphomatoid granulomatosis complex. Churg-Strauss syndrome responds well to glucocorticoids. Cytotoxic drugs appear necessary for ultimate control of Wegener's granulomatosis. Radiation therapy is effective in controlling polymorphic reticulosis/lymphomatoid granulomatosis when it is localized to one site. Evidence suggests that polymorphic reticulosis/lymphomatoid granulomatosis may be closely related to lymphoproliferative disorders.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001249:Asthma / Q000150:complications; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000150:complications; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000473:pathology*; D014890:Granulomatosis with Polyangiitis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000473:pathology*; D008230:Lymphomatoid Granulomatosis / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D012137:Respiratory System / Q000473:pathology; D013577:Syndrome; D014657:Vasculitis / Q000188:drug therapy / Q000473:pathology*
D000970:Antineoplastic Agents; D005938:Glucocorticoids