Age-related changes in oxygen consumption and the SDH activity of liver homogenate of male garden lizards: effect of malonate and short-term cold stress.
The respiratory rate of liver homogenate in the male garden lizard showed a decline with advancing age. The mitochondrial marker enzyme, SDH of the liver, reached a peak activity in the middle-aged group and then declined. Malonate inhibition of the enzyme activity was greater in young and middle-aged groups of lizards than in old. Short-term cold stress (1 h at 0--4 degrees C) showed a differential age effect inducing a decline in enzyme activity of the middle-aged group and a rise in the old.
D000375:Aging; D000818:Animals; D003080:Cold Temperature; D008099:Liver / Q000201:enzymology*; D008116:Lizards; D008297:Male; D008314:Malonates / Q000494:pharmacology*; D010101:Oxygen Consumption; D013312:Stress, Physiological / Q000201:enzymology*; D013385:Succinate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*
D008314:Malonates; D013385:Succinate Dehydrogenase