Failure to detect abnormal fatty acid profiles in serum lipoproteins in Friedreich's ataxia.
A recent report indicated an association between the spinocerebellar degeneration of Friedreich's ataxia and abnormal fatty acid profiles of the cholesterol ester fraction in both total plasma and high-density lipoprotein. In an effort to substantiate these findings in lipoproteins, we estimated fatty acid profiles of total high-density lipoprotein and the cholesterol esters of high- and low-density lipoproteins. Those profiles in 10 Friedreich's ataxia patients compared well with previously reported normal values and did not differ significantly from results in 10 age-matched controls.
D002788:Cholesterol Esters / Q000097:blood; D005227:Fatty Acids / Q000097:blood*; D005621:Friedreich Ataxia / Q000097:blood*; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood
D002788:Cholesterol Esters; D005227:Fatty Acids; D008074:Lipoproteins; D008077:Lipoproteins, LDL