Inhibition of mitochondrial oxidative phosporylation by 4-deoxyphorbol triester, a poisonous constituent of the latex sap of Euphorbia biglandulosa Desf.
D000244:Adenosine Diphosphate / Q000378:metabolism; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D066298:In Vitro Techniques; D008929:Mitochondria, Heart / Q000378:metabolism; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D010703:Phorbol Esters / Q000494:pharmacology*; D010704:Phorbols / Q000494:pharmacology*; D010947:Plants, Toxic; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013386:Succinates / Q000378:metabolism; D013395:Sucrose / Q000378:metabolism
C025632:4-deoxyphorbol triester; D010703:Phorbol Esters; D010704:Phorbols; D011506:Proteins; D013386:Succinates; D013395:Sucrose; D000244:Adenosine Diphosphate