Long-term treatment of rats with morphine decreases in vitro biosynthesis in and release of beta-endorphin from intermediate/posterior lobes of pituitary.
D000818:Animals; D004723:Endorphins / Q000096:biosynthesis / Q000378:metabolism*; D006220:Haloperidol / Q000494:pharmacology; D008297:Male; D008970:Molecular Weight; D009020:Morphine / Q000494:pharmacology*; D010649:Phenylalanine / Q000378:metabolism; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism*; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D004723:Endorphins; D010649:Phenylalanine; D009020:Morphine; D006220:Haloperidol