Further evidence for local osmotic coupling in the rabbit cornea.
1. The present experiments measure net fluxes of fluid, Cl- and HCO-3 across de-epithelialised rabbit corneas clamped between half chambers and bathed in Ringer solutions. 2. Net fluxes of HCO-3 and fluid occurred together across the cornea from stroma to aqueous when HCO-3 and CO2 were present in the bathing solution. 3. No net trans-corneal C1-flux was found 4. The initiation of fluid flow in the presence of HCO-3 and CO2 cannot be accounted for by bulk-phase osmotic flow across the cornea.
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism*; D001692:Biological Transport; D001834:Body Water / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism*; D003315:Cornea / Q000378:metabolism*; D066298:In Vitro Techniques; D009997:Osmotic Pressure; D011817:Rabbits
D001639:Bicarbonates; D002712:Chlorides