title: [Therapy of juvenile iron deficiency with bivalent iron dragees (Fe2-fumarate, succinate, sulfate). Controlled double-blind study].
abstract: In 53 children with moderate iron deficiency (haemoglobin 7,5 to 12 g/dl) divalent iron salts as tablets (59Fe2+-fumarate, -succinate, -sulfate) were tested versus placebo (controlled double-blind study). Gastrointestinal side effects were most frequently seen with iron succinate (50%) and iron sulfate (25%). Therapeutic success as measured by haemoglobin regeneration was not significantly different among the three iron salts, but significantly more effective than in the placebo group. Children beyond the age of two years mostly refused the application of tablets and should be supplied with liquid preparations.
mesh_terms: D000747:Anemia, Hypochromic / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004361:Drug Tolerance; D005296:Ferrous Compounds / Q000627:therapeutic use*; D006801:Humans; D007501:Iron / Q000627:therapeutic use*; D010919:Placebos; D013386:Succinates / Q000627:therapeutic use; D013431:Sulfates / Q000627:therapeutic use; D013607:Tablets
chemical_list: D005296:Ferrous Compounds; D010919:Placebos; D013386:Succinates; D013431:Sulfates; D013607:Tablets; D007501:Iron
vernacular_title: Therapie des Eisen-Mangels bei Kindern mit 2wertigen Eisensalz-Dragees (Fe2+-Fumarat, -Succinat, -Sulfat), kontrollierte Doppelblind-Studie.