Relationship between lipids and occlusive coronary artery disease.
Total cholesterol level, high-density lipoprotein (HDL) cholesterol level, and the ratio of total cholesterol/HDL cholesterol and triglyceride level were determined in 128 consecutive patients undergoing coronary arteriography for evaluation of chest pain. Greater than 50% occlusive coronary artery disease was more prevalent in patients with either a high total cholesterol level, triglyceride level, or total cholesterol/HDL ratio, or a low HDL cholesterol level. Closer analysis of the extent of occlusive coronary artery disease indicated that the HDL cholesterol level was a better predictor of coronary artery disease than total cholesterol or triglyceride levels. The ratio of total cholesterol/HDL cholesterol, however, had a wider discrimination in identifying patients with both single-vessel or multivessel disease. This ratio should be a useful adjunct in assessing the risk of coronary artery disease.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D008055:Lipids; D008075:Lipoproteins, HDL; D014280:Triglycerides; D002784:Cholesterol