Transtympanic and surface recordings in the diagnosis of retrocochlear disorders.
A series of patients presenting with subsequently surgically confirmed central tumour involving the auditory pathways were investigated using both transtympanic electrocochleography (TT ECochG) and surface recordings of brainstem evoked responses (BER). While ECochG allows a detailed study of peripheral function, BER allow the investigation of neural conduction up to the level of the inferior colliculus. Valuable information can be obtained from: (1) comparison of the amplitudes of the sensory and neural components of the ECochG; (2) comparison of ECochG, BER and auditory thresholds; (3) time interval measurements between the auditory nerve response (N1 on the ECochG) and the inferior colliculus (wave P4-5 on BER); (4) contralateral comparisons. Similar measurements performed in pure cochlear pathologies, mainly in Meniere's disease, yielded very significant differences.
D001299:Audiometry / Q000379:methods*; D001300:Audiometry, Evoked Response / Q000379:methods*; D001309:Auditory Threshold; D001933:Brain Stem / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004568:Electrodiagnosis / Q000379:methods*; D006801:Humans; D008575:Meniere Disease / Q000175:diagnosis; D009464:Neuroma, Acoustic / Q000175:diagnosis*; D013997:Time Factors; D014432:Tympanic Membrane / Q000503:physiopathology*