Bilateral necrotising scleritis with marginal corneal ulceration after cataract surgery in a patient with vasculitis.
The onset of bilateral necrotising scleritis and marginal corneal ulceration after cataract surgery are described in a patient with diffuse vasculitis syndrome. The finding of immune complexes in this patient's tissue biopsy suggests that they are the cause of a localised primary vasculitis triggered by surgical inflammation. Clinically, this patient's marginal corneal ulceration preceded the scleral necrosis. A past history of orbital inflammation may have been due to a posterior scleritis. The corneal ulcerations responded to conjunctival debridement and steroids. The scleral necrosis was unresponsive to the 2 anti-inflammatory preparations tried, and the patient eventually went into remission while off all treatment.
D000368:Aged; D000936:Antigen-Antibody Complex; D002386:Cataract / Q000150:complications; D002387:Cataract Extraction / Q000009:adverse effects*; D003228:Conjunctiva / Q000276:immunology / Q000473:pathology; D003320:Corneal Ulcer / Q000209:etiology*; D005128:Eye Diseases / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D007910:Lenses, Intraocular / Q000009:adverse effects; D009336:Necrosis; D012590:Sclera / Q000473:pathology; D014657:Vasculitis / Q000150:complications* / Q000276:immunology
D000936:Antigen-Antibody Complex