Paroxysmal nocturnal haemoglobinuria in pregnancy: case report.
Pregnancy in a woman with paroxysmal nocturnal haemoglobinuria was complicated by hepatic venous thrombosis, portal hypertension and haematemesis due to gross oesophageal varices. Labour was induced and a live female infant was born. Dural sinus thrombosis and intracerebral haemorrhage resulted in death on the 46th day post partum. A review of the literature shows that venous thrombosis is common in paroxysmal nocturnal haemoglobinuria.
D000328:Adult; D006502:Budd-Chiari Syndrome / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy; D011644:Puerperal Disorders / Q000209:etiology
D006493:Heparin