Cumulative effects of repeated doses of compounds transformed into reactive metabolites.
D000818:Animals; D001711:Biotransformation; D001969:Bromobenzenes / Q000494:pharmacology; D003035:Cobalt / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051381:Rats; D013997:Time Factors; D014018:Tissue Distribution; D014241:Trichloroethylene / Q000494:pharmacology; D014752:Vinyl Chloride / Q000494:pharmacology
D001969:Bromobenzenes; D014241:Trichloroethylene; D003035:Cobalt; D003577:Cytochrome P-450 Enzyme System; D005978:Glutathione; D014752:Vinyl Chloride