A comparison of erythrocyte glutathione S-transferase activity from human foetuses and adults.
Glutathione S-transferase activity was measured in partially purified haemolysates of erythrocytes from human foetuses and adults. Enzyme activity was present in erythrocytes obtained between 12 and 40 weeks of gestation. The catalytic properties of the enzyme from foetal cells were similar to those of the enzyme from adult erythrocytes, indicating that probably only one form of the erythrocytes enzyme exists throughout foetal and adult life.
D002850:Chromatography, Gel; D004137:Dinitrochlorobenzene / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology*; D005312:Fetal Blood / Q000187:drug effects / Q000201:enzymology; D005978:Glutathione / Q000494:pharmacology; D005982:Glutathione Transferase / Q000097:blood*; D006461:Hemolysis; D006801:Humans; D008970:Molecular Weight
D004137:Dinitrochlorobenzene; D005982:Glutathione Transferase; D005978:Glutathione