[Alpha-tocopherol inhibition of erythema in skin photosensitized by 8-methoxypsoralen].
Irradiation of the rabbit and human skin by near UV light (wave lengths greater than 320 nm) in the presence of 8-methoxypsoralen produced erythema, pigmentation and some changes in the mechanical and electric properties. All the photobiological effects mentioned were inhibited by alpha-tocopherol if it was applied before irradiation. When applied after exposure to irradiation alpha-tocopherol appeared to be ineffective.
D000818:Animals; D004890:Erythema / Q000517:prevention & control*; D008297:Male; D008730:Methoxsalen / Q000037:antagonists & inhibitors*; D010787:Photosensitivity Disorders / Q000517:prevention & control*; D011817:Rabbits; D012867:Skin / Q000528:radiation effects*; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014810:Vitamin E / Q000627:therapeutic use*
D014810:Vitamin E; D008730:Methoxsalen
Ingibirovanie alpha-tokoferolom éritemy kozhi, fotosensibilizirovannoĭ 8-metoksipsoralenom.