Effect of sympathectomy on platelet aggregation and blood coagulation in rats.
It is shown that the ability of blood platelets to aggregate in partially and completely sympathectomized rats is significantly lower than in intact animals. The blood clotting system of sympathectomized rats is hyperactive. The sympathectomy-provoked changes may be due to the increased content of adrenaline in the blood.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D004837:Epinephrine / Q000097:blood; D006145:Guanethidine / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects*; D013917:Thrombin / Q000494:pharmacology / Q000502:physiology
D000244:Adenosine Diphosphate; D013917:Thrombin; D004837:Epinephrine; D006145:Guanethidine