title: Children at risk for schizophrenia.
abstract: Etiological factors in the transmission of schizophrenia are reviewed; models include psychogenic, genetic, gene/environment interaction. Investigation of premorbid history is discussed employing retrospective, follow-back, follow-up, and prospective studies. Certain symptom clusters (attentional and cognitive deficits, poor socialization, withdrawal) in genetically predisposed individuals may predict schizophrenia. Stress-reducing therapeutic environments are proposed.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010287:Parent-Child Relations; D012306:Risk; D012561:Schizophrenia, Childhood / Q000235:genetics*; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000235:genetics