Infectious drug resistance during an outbreak of samonellosis.
The sudden acquisition of aminoglycoside resistance among Salmonella group C1 isolates causing summer diarrhoea raised the possibility oif plasmid-mediated reistance. The demonstration of circular DNA species in the resistant, but not in the sensitive salmonellae and the transfer by conjugation of antibiotic resistance to a sensitive strain of Escherichic coli, was consistent with plasmid-mediated resistance.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D012475:Salmonella / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D012480:Salmonella Infections / Q000382:microbiology*; D013019:South Africa; D014169:Transformation, Bacterial
D000900:Anti-Bacterial Agents