Calorimetric studies of lipid phase transitions in native and heat-denatured membranes of beef heart submitochondrial particles.
The lipids in beef heart submitochondrial particles undergo a broad reversible endothermic phase change centered at about -10 degrees C. Following protein denaturation, a new reversible transition centered at about 20 degrees C appears. The extracted lipids from these membranes exhibit thermal behavior that is essentially identical to the lipid transition in the intact membrane after protein denaturation. A role for this latent pool of higher-melting lipids is proposed.
D000818:Animals; D002151:Calorimetry; D002417:Cattle; D005615:Freezing; D008563:Membrane Lipids / Q000032:analysis; D008565:Membrane Proteins / Q000032:analysis; D008928:Mitochondria / Q000648:ultrastructure*; D008929:Mitochondria, Heart / Q000648:ultrastructure*; D011489:Protein Denaturation; D013367:Submitochondrial Particles / Q000648:ultrastructure*
D008563:Membrane Lipids; D008565:Membrane Proteins