Anti-A autoantibodies with unusual properties in a patient on renal dialysis.
A blood group A1 patient on renal dialysis developed transient low-titre, high-avidity anti-A autoantibodies and concurrently a gross depression of the A antigen. The antibodies were clearly anti-A and had no association with I, i or N antigens. They reacted in saline, papain and antiglobulin systems but were inactivated by albumin. Their pathogenesis is obscure.
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D000371:Agglutination; D000906:Antibodies; D001323:Autoantibodies / Q000276:immunology*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000276:immunology* / Q000628:therapy; D037102:Lectins / Q000276:immunology; D008623:Mercaptoethanol / Q000494:pharmacology; D006435:Renal Dialysis
D000017:ABO Blood-Group System; D000906:Antibodies; D001323:Autoantibodies; D037102:Lectins; D008623:Mercaptoethanol