title: [Hemodynamics and myocardial O2 consumption at induction of anesthesia (author's transl)].
abstract: The hemodynamics and the myocardial oxygen consumption during sleep and induction of anesthesia was studied in 10 patients with good left heart function (group I) and in 8 patients with bad left function (group II). Anesthesia was induced with diazepam (0.1 mg/kg BW), fentanyl (0.01 mg/kg BW), etomidate (0.2 mg/kg BW), and pancuronium (0.1 mg/kg BW). Four min after induction under ventilation with mask the cardiac index (CI) in both groups and the whole body oxygen consumption (VO2) diminished in exact the same degree. After intubation in patients of group I the CI and the VO2 decreased further, the arterio-venous oxygen content difference (avDO2) remained constant. In patients of group II the CI decreased to 0.9 1/min x m2, the avDO2 increased to 9.9 Vol%.
mesh_terms: D000768:Anesthesia, General; D003975:Diazepam / Q000494:pharmacology; D005045:Etomidate / Q000494:pharmacology; D005283:Fentanyl / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D010101:Oxygen Consumption / Q000187:drug effects*; D010197:Pancuronium / Q000494:pharmacology
chemical_list: D010197:Pancuronium; D003975:Diazepam; D005283:Fentanyl; D005045:Etomidate
vernacular_title: Hämodynamik und myokardialer Sauerstoffverbrauch bei Narkoseeinleitung.