title: Total synthesis of heterocyclic steroids, part VI. Synthesis of (+/-)-3-methoxy-6-aza-12-thia-12-dioxo-b-nor-14 beta-estra-1,3,5(10),8-tetraen-17 alpha-OL.
abstract: With 7-hydroxy-7a-methyl-4-oxo-cyclopenta(b)tetrahydrothiopyran-1-dioxide (III) as the CD part, the synthesis of the title compound (II) was achieved by the Fischer indole synthesis.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D003500:Cyclization; D004963:Estrenes / Q000138:chemical synthesis*; D008722:Methods; D008968:Molecular Conformation; D013260:Steroids, Heterocyclic / Q000138:chemical synthesis*; D014961:X-Ray Diffraction
chemical_list: C026348:3-methoxy-6-aza-12-thia-12-dioxo-B-nor-14 beta-estra-1,3,5(10),8-tetraen-17 alpha-ol; D004963:Estrenes; D013260:Steroids, Heterocyclic