Testosterone secretion by the isolated canine testis after controlled infusions of HCG.
A technique is described for perfusion of isolated canine testes. Infusing the testes with various amounts of hCG identified a rate of 0.075 i.u./min as one which reliably increased testosterone secretion into the spermatic venous effluent without producing maximal testosterone production.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D004285:Dogs; D008297:Male; D009924:Organ Culture Techniques; D013737:Testis / Q000187:drug effects / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism*
D006063:Chorionic Gonadotropin; D013739:Testosterone