Human placental beta-endorphin.
Human acid-acetone placental powder (PP) has corticotrophin-like and beta-endorphin(beta-EP)-like activity. In a beta-EP radioimmunoassay the PP showed a potency of 4.82 ng/mg protein. In Sephadex G-75 filtration and high pressure liquid chromatography, the beta-EP-like activity of PP was found in the corresponding chromatographic fractions as standard beta-EP. The PP tested for opiate activity in a radioreceptor assay showed a dilution curve parallel to that of synthetic beta-EP.
D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D004723:Endorphins / Q000032:analysis* / Q000276:immunology / Q000502:physiology; D005260:Female; D006801:Humans; D010920:Placenta / Q000032:analysis*; D011247:Pregnancy; D011863:Radioimmunoassay; D011869:Radioligand Assay
D004723:Endorphins