[Rapid determination of MB fraction of serum creatine kinase in the diagnosis of acute myocardial infarction (author's transl)].
The behaviour of the myocardial fraction of creatine kinase has been studied in a group of 80 patients diagnosed as having an acute myocardial infarction. The method of selective activation with dithiothreitol was employed. This technique enables the isoenzyme quantification in less than 15 minutes, which represents a great advantage in comparison to other complex methods used in the past. According to the time of evolution of the infarction the patients were classified into four groups and comparative statistical studies were carried out between these groups and the group of 20 normal controls. The early increase of the myocardial fraction is stressed, even when creatine kinase is still within normal limits. Literature on this topic is reviewed and a systematic determination of the myocardial fraction of serum creatine kinase in the intensive Coronary Units is recommended in order to certainly diagnose myocardial infarction as soon as possible.
D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007527:Isoenzymes; D009203:Myocardial Infarction / Q000175:diagnosis / Q000201:enzymology*
D007527:Isoenzymes; D003402:Creatine Kinase
Diagnóstico del infarto agudo de miocardio por dosificación rápida de la fracción MB de la creatincinasa sérica.