title: Effects of altered thyroid state on the inhibition produced by locus coeruleus in Purkinje cells in the rat.
abstract: The number of cerebellar Purkinje cells inhibited after locus coeruleus stimulation was found to be greater in hyperthyroid rats than in control healthy animals; these in turn showed a higher percentage of inhibited cells than hypothyroid rats. It is concluded that thyroid hormone is capable of modulating synaptic activity in the LC-PC pathway.
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D005260:Female; D006980:Hyperthyroidism / Q000503:physiopathology*; D007037:Hypothyroidism / Q000503:physiopathology*; D008125:Locus Coeruleus / Q000503:physiopathology*; D008297:Male; D011689:Purkinje Cells / Q000502:physiology*; D051381:Rats