title: Human proinsulin, V: synthesis of a protected peptide fragment corresponding to the sequence 24-45 of the prohormone.
abstract: The protected peptide fragment 24-45 of human proinsulin, Bpoc-Phe-Phe-Tyr(But)-Thr-(But)-Pro-Lys(Boc)-Thr(But)-Arg(H2SO4)-Arg-(H2SO4)-Gl u(OBut)-Ala-Glu(OBut)-Asp(OBut)-Leu-Gln-Val-Gly-Gin-Val-Glu(OBut)-Leu-Gly-Oh, was synthesized from the two intermediate fragments 24--33 and 34--45, and purified by countercurrent distribution in the carbon tetrachloride system (K = 2.5).
mesh_terms: D000595:Amino Acid Sequence; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism*; D011384:Proinsulin / Q000138:chemical synthesis*
chemical_list: D010446:Peptide Fragments; D011384:Proinsulin