Kindling of seizures with low-frequency electrical stimulation.
Repeated application of electrical stimulation to the amygdala at a frequency of 3 Hz resulted in the development of afterdischarge and behavioral seizures. The rate of low-frequency kindling was faster than that of kindling with conventional 60 Hz stimulation, but the form of the seizures kindled with the two frequencies of stimulation was identical. Low-frequency kindling was obtained only when pulses of sufficient duration and intensity were administered.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D004292:Dominance, Cerebral / Q000502:physiology; D004558:Electric Stimulation / Q000379:methods; D005071:Evoked Potentials; D008297:Male; D051381:Rats; D012640:Seizures / Q000503:physiopathology*