title: Prostaglandins and congeners. 25. Inhibition of gastric acid secretion. Replacement of the carboxylate moiety of a prostaglandin with a hydroxymethylketo functional group.
mesh_terms: D000818:Animals; D003864:Depression, Chemical; D004285:Dogs; D005750:Gastric Juice / Q000378:metabolism*; D007659:Ketones; D000432:Methanol / Q000031:analogs & derivatives; D011465:Prostaglandins, Synthetic / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
chemical_list: D007659:Ketones; D011465:Prostaglandins, Synthetic; D000432:Methanol