Forsius-Eriksson syndrome: its relation to the Nettleship-Falls X-linked ocular albinism.
On the basis of clinical data, it had previously been proposed that the Forsius-Eriksson syndrome is identical to Nettleship-Falls X-linked ocular albinism. We performed biopsies of clinically-normal skin in patients with the Forsius-Eriksson syndrome to look for the abnormal melanosomes characteristic of Nettleship-Falls X-linked ocular albinism. There were no abnormalities in the melanosomes of patients with Forsius-Eriksson syndrome. Thus, this syndrome is distinct from the Nettleship-Falls disorder.
D000417:Albinism / Q000145:classification / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000648:ultrastructure; D012730:Sex Chromosomes; D012867:Skin / Q000648:ultrastructure; D013577:Syndrome; D014960:X Chromosome