Neurotoxicity of N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride (DSP 4) on noradrenergic neurons is mimicked by its cyclic aziridinium derivative.
D000588:Amines / Q000494:pharmacology*; D000818:Animals; D001596:Benzylamines / Q000494:pharmacology*; D001923:Brain Chemistry / Q000187:drug effects; D003891:Desipramine / Q000494:pharmacology; D005260:Female; D007276:Injections, Intraventricular; D051379:Mice; D009206:Myocardium / Q000378:metabolism; D009422:Nervous System Diseases / Q000139:chemically induced; D009474:Neurons / Q000187:drug effects*; D009638:Norepinephrine / Q000378:metabolism; D013564:Sympathetic Nervous System / Q000187:drug effects*; D013997:Time Factors
D000588:Amines; D001596:Benzylamines; C012102:DSP 4; D003891:Desipramine; D009638:Norepinephrine