Effect of atropine sulfate in pulmonary hypertrophic osteoarthropathy.
A 49-year-old patient with pulmonary hypertrophic osteoarthropathy was treated with 0.4 mg of atropine sulfate every 4 hours for 14 days. A good clinical response was obtained as measured by handgrip strength, range of motion, and quantitative thermography. Chemical vagotomy supports the hypothesis of the vagal reflex as the pathophysiological mechanism in pulmonary hypertrophic osteoarthropathy.
D001285:Atropine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000188:drug therapy*; D005082:Physical Exertion; D013817:Thermography; D014628:Vagotomy
D001285:Atropine