Transmission of a balanced homologous t(22q;22q) translocation from mother to normal daughter.
The transmission of a t(22q;22q) translocation is reported. The mother had had multiple miscarriages and carried both t(22q;22q) and t(22p;22p) portions of the rearrangement in a portion of her cells. The phenotypically normal daughter, who was the proband and was referred because of multiple miscarriages, also carried the t(22q;22q) translocation.
D000026:Abortion, Habitual / Q000235:genetics; D000328:Adult; D002904:Chromosomes, Human, 21-22 and Y; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D011247:Pregnancy; D014178:Translocation, Genetic