title: Efferent projections of the deep mesencephalic nucleus (pars medialis) in the rat.
abstract: The projections of the medial part of the deep mesencephalic nucleus (DMN) were traced by autoradiography and retrograde horseradish peroxidase (HRP) techniques. No ascending projections were observed from the medial part of the DMN; however, two groups of descending fibers were observed. One group crossed the midline and coursed to the caudal part of the red nucleus. At this point, these fibers divided into two distinct bundles. One bundle of fibers passed caudally to terminate in the contralateral pontine reticular nucleus, superior olive-trapezoid body complex, gigantocellular nucleus, and upper cervical spinal cord. The other bundle entered the medial longitudinal fasciculus (MLF) and coursed through the pons and medulla without termination, to enter the cervical spinal cord where terminations were noted in the dorsal horn. The other group of fibers from the medial DMN descended through the ipsilateral pons and medulla, projecting to the pontine reticular nucleus, superior olive-trapezoid body complex, gigantocellular nucleus, and upper cervical spinal cord. These findings indicate that the medial part of the DMN is likely to be involved in complex sensorimotor events via reticulobulbar and reticulospinal connections.
mesh_terms: D000818:Animals; D001345:Autoradiography; D001931:Brain Mapping / Q000379:methods; D004525:Efferent Pathways / Q000033:anatomy & histology; D006735:Horseradish Peroxidase; D008526:Medulla Oblongata / Q000033:anatomy & histology; D009847:Olivary Nucleus / Q000033:anatomy & histology; D011149:Pons / Q000033:anatomy & histology; D051381:Rats; D012154:Reticular Formation / Q000033:anatomy & histology; D013116:Spinal Cord / Q000033:anatomy & histology; D013681:Tegmentum Mesencephali / Q000033:anatomy & histology*
chemical_list: D006735:Horseradish Peroxidase