title: Ileosigmoid knot.
abstract: The ileosigmoid knot (ISK) is a variant of midgut volvulus in which a loop of ileum wraps around the base of an elongated sigmoid colon and passes beneath itself forming a knot. A long small bowel mesentery and a sigmoid colon on a narrow pedicle are necessary prerequisites, but the wide variation in incidence of ISK across the world seems to be related to dietary habits. Rapid fluid resuscitation, preoperative broad-spectrum antibiotics, methylprednisolone in the presence of shock, and immediate laparotomy may improve the high mortality.
mesh_terms: D000328:Adult; D012809:Colon, Sigmoid / Q000601:surgery*; D004032:Diet / Q000009:adverse effects; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D007082:Ileum / Q000601:surgery*; D007416:Intestinal Perforation / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D011859:Radiography; D012810:Sigmoid Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*