title: Production and activity of the Kav 0.64 pheromone fraction of Nippostrongylus brasiliensis.
abstract: The pheromone fraction that elutes at Kav 0.64 in gel filtration showed significantly reduced activity for the male's locomotor response when obtained from 10-day-old, or older, female Nippostrongylus brasiliensis. This fraction, obtained from males and females that were admixed prior to extraction, revealed a sex-ratio dependent increase in pheromone activity at 50%:50% male:female according to the male's locomotor response. The female's response to mixed sex pheromone at Kav 0.64 showed no distinct sex-ratio effect. The pheromone that was contained within the female helminths as the Kav 0.64 elutant exhibited little variation in its level, based on collection period studies up to 3 hr. However, exposure of females to male worms altered the amount of pheromone at Kav 0.64 that was recovered from maceration and gel filtration of female helminths, presumably owing to pheromone release.
mesh_terms: D000375:Aging; D000818:Animals; D005260:Female; D008297:Male; D009068:Movement; D009559:Nippostrongylus / Q000032:analysis / Q000502:physiology*; D010675:Pheromones / Q000032:analysis / Q000502:physiology*; D012737:Sex Factors
chemical_list: D010675:Pheromones