[Polyamine formation and development of functional hypertrophy in skeletal muscles with increased activity].
Cycloheximide caused no changes in activation of arginase and ornitine-sigma-ketoglutarate transaminase during loads, but the activation of ornitine decarboxylase and putrescine and polyamines production was sharply reduced. Physical load caused a significantly lower activation of enzymes of ornitine metabolism and a smaller production of polyamines in muscles of trained animals. The extent of polyamines synthesis is positively correlated with the magnitude of muscles work hypertrophy.
D000818:Animals; D001119:Arginase / Q000378:metabolism; D001120:Arginine / Q000032:analysis; D003513:Cycloheximide / Q000494:pharmacology; D009132:Muscles / Q000032:analysis / Q000378:metabolism*; D009955:Ornithine Decarboxylase / Q000378:metabolism; D009953:Ornithine-Oxo-Acid Transaminase / Q000378:metabolism; D005082:Physical Exertion; D011073:Polyamines / Q000096:biosynthesis*; D011700:Putrescine / Q000032:analysis; D051381:Rats; D013095:Spermidine / Q000032:analysis; D013096:Spermine / Q000032:analysis
D011073:Polyamines; D013096:Spermine; D001120:Arginine; D003513:Cycloheximide; D009953:Ornithine-Oxo-Acid Transaminase; D001119:Arginase; D009955:Ornithine Decarboxylase; D013095:Spermidine; D011700:Putrescine
Obrazovanie poliaminov i razvitie rabocheĭ gipertrofii skeletnykh myshts pri povyshennoĭ ikh deiatel'nosti.