[Pre- and postoperative endocrinologic findings in patients with acromegaly in transsphenoidal surgery].
34 (69%) of 49 patients suffering from acromegaly had normal growth hormone levels after transnasal-transsphenoidal adenotomy. The operation impaired the other pituitary endocrine functions in a few cases only, these being improved in other cases. There were few operative complications (meningitis 3, significant peroperative bleeding 3, longer lasting diabetes insipidus 5). Transnasal-transsphenoidal selective adenomectomy with the aid of a dissecting microscope has a lower morbidity and mortality than the transfrontal approach. Its results are good in comparison to other therapies, especially if the postoperative complications and endocrine losses of function are considered.
D000172:Acromegaly / Q000503:physiopathology*; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000378:metabolism; D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*; D011388:Prolactin / Q000378:metabolism; D013100:Sphenoid Bone / Q000601:surgery; D013963:Thyroid Hormones / Q000378:metabolism
D000305:Adrenal Cortex Hormones; D013963:Thyroid Hormones; D011388:Prolactin; D013006:Growth Hormone
Prä- und postoperative endokrinologische Befunde bei transsphenoidal operierten Patienten mit Akromegalie.