[Polarization of nerve terminals induced by direct electrical stimulation of frog skeletal muscle].
Direct electrical stimulation (20-200/sec) of the frog skeletal muscle elicited a slow electrical response of motor nerve terminals reflecting a hyperpolarization shift of their membrane potential. A new technique for dissociation of electrical and mechanical activities of muscular fibers revealed hyperpolarization of motor terminals due to a series of APs of the muscular fibers. The terminals hyperpolarizaton response is augmented by 2-3 times with 10 mM of theophyllin. Possible mechanisms of reversed action of active muscular fibers on nerve terminals, are discussed.
D000200:Action Potentials; D000818:Animals; D001001:Anura; D004558:Electric Stimulation; D009119:Muscle Contraction; D009469:Neuromuscular Junction / Q000187:drug effects / Q000502:physiology*; D013806:Theophylline / Q000494:pharmacology
D013806:Theophylline
Poliarizatsiia nervnykh terminaleĭ, vyzvannaia priamoĭ élektricheskoĭ stimuliatsieĭ skeletnoĭ myshtsy liagushki.