title: Exertional heat stroke: the runner's nemesis.
abstract: Heat stroke in distance runners is increasing in frequency. A case is reported of a 41-year-old man who collapsed during a 10-km "fun run" held when the temperature was 31.6 degrees C and the humidity 80%. Acute renal failure (serum creatinine level 1530 mumol/l [17.3 mg/dl]), rhabdomyolysis, disseminated intravascular coagulation and hepatic damage complicated the clinical picture. Repeated peritoneal dialysis and one cycle of hemodialysis because of a very high serum level of uric acid (1.23 mmol/l [20.7 mg/dl]) were required. Although the illness was prolonged, recovery was almost complete, and 4 months after the man's collapse the serum creatinine level had fallen to 133 mumol/l (1.5 mg/dl).
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000328:Adult; D001265:Athletic Injuries / Q000150:complications / Q000503:physiopathology*; D001774:Blood Chemical Analysis; D001831:Body Temperature; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006331:Heart Diseases / Q000209:etiology; D006359:Heat Exhaustion / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D009212:Myoglobinuria / Q000209:etiology; D009461:Neurologic Manifestations; D012420:Running