Investigations of the effect of F2 alpha-prostaglandin--lutalyse on the volume of sheep abomasal juice, its acidity and proteolytic power.
In the experiments carried out on 3 sheep (males) it was demonstrated that intramuscular administration of Lutalyse in optimal doses (130-170 g/kg of body weight) caused a rise in the volume of juice, the amount of free HCl, and the value of total acidity, as well as an increase in the specific activity (Anson's milliunits in ml) and total activity (specific activity multiplied by juice volume in each sample). It was found that Lutalyse (an analogue of PGF2 alpha) increased the secretory activity of the glandular cells of the abomasum and stimulated particularly powerfully the chief cells, with consequent rise in the proteolytic power of the juice.
D000018:Abomasum / Q000502:physiology*; D000818:Animals; D015237:Dinoprost / Q000031:analogs & derivatives*; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000032:analysis / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D008297:Male; D011461:Prostaglandins F, Synthetic / Q000494:pharmacology*; D012756:Sheep / Q000502:physiology*; D013268:Stimulation, Chemical
D011461:Prostaglandins F, Synthetic; D015237:Dinoprost; C010714:dinoprost tromethamine