A comparison between terminally radioiodinated hexadecenoic acid (I-HA) and 201Tl-thallium chloride in the dog heart. Implications for the use of I-HA for myocardial imaging.
The regional myocardial distribution of 131I-16-iodo-9-hexadecenoic acid (131I-HA) and 201Tl-thallium chloride (201TlCl) was determined in normal dogs and after occlusion of a coronary artery. The uptake of 131I-HA was about 20% lower than that of 201TlCl but the ratio 201Tl/131I was the same for the whole myocardium within narrow limits for normal as well as infarcted tissue. The potential of 123I-HA as a radiopharmaceutical for diagnosis of myocardial defects is discussed.
D000818:Animals; D004285:Dogs; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D007457:Iodine Radioisotopes; D008297:Male; D010169:Palmitic Acids; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013793:Thallium
D007457:Iodine Radioisotopes; D010169:Palmitic Acids; D011868:Radioisotopes; D013793:Thallium