title: The determination of total cholinesterase in rectal biopsy tissue from patients with Hirschsprung's disease.
abstract: A spectrophotometric method is described for the quantitative biochemical assay of total cholinesterase in rectal biopsy tissue. Significantly increased enzyme activity was found in this tissue from patients with Hirschsprung's disease, suggesting that the assay has diagnostic value.
mesh_terms: D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D002802:Cholinesterases / Q000032:analysis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008531:Megacolon / Q000201:enzymology* / Q000473:pathology; D012007:Rectum / Q000201:enzymology* / Q000473:pathology
chemical_list: D002802:Cholinesterases