[Malignant tumour of adrenal with feminizing syndrome and primary hyperaldosteronism (author's transl)].
Feminizing tumour of adrenals are rare. Gynecomasty, abdominal tumour are the more frequently observed symptoms. The described case in a 38 years aged man is of special interest because of association with primary hyperaldosteronism. Studies in vivo and in vitro are reported. In vitro studies shown a high 18 hydroxylation biosynthetic activity of tumoral fragment and a great synthesis of polar phenolsteroids with testosterone as precurseurs.
D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism; D000328:Adult; D005262:Feminization / Q000209:etiology*; D006801:Humans; D006900:Hydroxylation; D006929:Hyperaldosteronism / Q000150:complications*; D006973:Hypertension / Q000150:complications; D066298:In Vitro Techniques; D008297:Male
Corticosurrénalome malin avec syndrome féminisant et hyperaldostéronisme primaire. Etude clinique et biochimique ("in vivo", "in vitro").