title: First-third ejection fraction at rest compared with exercise radionuclide angiography in assessing patients with coronary artery disease.
abstract: To compare two methods of evaluating patients with coronary artery disease, the authors assessed the ejection fraction (EF) during the first-third (1/3) of systole by first-pass radionuclide angiography and the EF response to exercise in 22 normal individuals and 40 patients. The 1/3 EF was calculated by averaging 3--5 beats on the time--activity curve. Exercise EFs were obtained by gated cardiac imaging. The results are shown below, including the per cent change in EF with exercise (% EF). (Formula: see text) p less than 0.05 vs. normals; p less than 0.001 vs. normals; all results are +/- SD. Thirty per cent of patients had a depressed EF, 98% had a depressed 1/3 EF, and 88% had an abnormal EF response to exercise. It is concluded that the 1/3 EF by first-pass radionuclide angiography at rest may be at least as sensitive in identifying patients with coronary artery disease as the EF response to exercise.
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000175:diagnosis; D002302:Cardiac Output; D003327:Coronary Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D011877:Radionuclide Imaging; D012146:Rest; D013318:Stroke Volume