Detection of hypersensitivity in allergic drug hepatitis.
Current evidence for the role of immune mechanisms in drug-induced liver disease is briefly surveyed. Cell-mediated immune reactions are frequently reported in the disease process, while humoral sensitization is poorly documented. The use and limitations of new diagnostic techniques in identifying drug hypersensitivity are discussed.
D000936:Antigen-Antibody Complex; D001323:Autoantibodies / Q000032:analysis; D056486:Chemical and Drug Induced Liver Injury / Q000276:immunology* / Q000473:pathology; D006241:Haptens; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D007111:Immunity, Cellular
D000936:Antigen-Antibody Complex; D001323:Autoantibodies; D006241:Haptens