Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
D000477:Alkylating Agents / Q000378:metabolism*; D000818:Animals; D001711:Biotransformation; D005663:Furans / Q000378:metabolism; D008168:Lung / Q000378:metabolism*; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008861:Microsomes / Q000378:metabolism*; D008862:Microsomes, Liver / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D013729:Terpenes / Q000378:metabolism*
D000477:Alkylating Agents; D005663:Furans; D013729:Terpenes; D009249:NADP; D008748:Methylcholanthrene; C001470:4-ipomeanol; D010634:Phenobarbital