title: Biocarbon urinary conduit: laboratory experience and clinical applications.
abstract: A new urinary conduit utilizing pure vitreous carbon has been used successfully in dogs. Pure carbon appears to be inert with respect to urine and urothelium. Lack of urinary salt encrustation on the exposed surface provides a well-functioning urinary conduit for vesical drainage. Twenty-one vesicostomies were performed in dogs. Careful follow-up and histologic studies of removed specimens were done to establish the biocompatibility of pure carbon. All vesicostomies functioned well. A description of the device, protocol, and results of laboratory experimentation are outlined. The surgical procedure is explained in detail. Results encourage the clinical trial of these devices in humans. Indications include patients with neurogenic vesicla dysfunction and those with total urinary incontinence, both of which require permanent indwelling catheters.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002244:Carbon; D002408:Catheters, Indwelling; D004285:Dogs; D001743:Urinary Bladder / Q000601:surgery; D001750:Urinary Bladder, Neurogenic / Q000628:therapy; D014546:Urinary Catheterization / Q000295:instrumentation / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D002244:Carbon