title: [State of the thyroid gland C-cells in rats after a flight on Kosmos-type biosatellites (based on morphological study data)].
abstract: Calcitonin-secreting cells (C-cells) of the thyroid glands from 51 SPF Wistar rats flown for 18.5 to 22 days aboard biosatellites Cosmos-605, 782 and 936 and sacrificed 4.5--13 hours, 1--2 and 25--27 days after recovery were examined histologically and karyometrically. Vivarium (57) and synchronous (58) rats were used as controls. Variations in the nuclear volume of C-cells and their density were shown to depend on the experimental conditions and time interval elapsed after recovery. Morphological changes in C-cells were assumed to be associated with alterations in calcium metabolism during an exposure of rats to weightlessness, artificial gravity and Earth gravity.
mesh_terms: D000818:Animals; D002116:Calcitonin / Q000378:metabolism*; D006651:Histocytochemistry; D007620:Karyometry; D008297:Male; D051381:Rats; D013026:Space Flight; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism; D013997:Time Factors; D014586:USSR; D014893:Weightlessness
chemical_list: D002116:Calcitonin
vernacular_title: Sostoianie C-kletok shchitovidnoĭ zhelezy u krys posle poleta na biosputnikakh tipa "Kosmos" (po dannym morfologicheskogo issledovaniia).