[Function activity of blood polynuclears according to results of the nitroblue tetrazolium reaction in inhabitants of the Far North].
The functional activity of polynuclear cells was studied in clinically healthy males aged 20-45 years constantly living in medium latitudes (the control group) and high latitudes (the experimental group). In persons who had lived in the North for a period of 6 months to 10 years and more the results of the spontaneous test with the use of nitrotetrazolium blue differed slightly from those in the control group, whereas after the stimulation of blood neutrophils with bacterial endotoxin these results proved to be significantly lower than those in the control group. With the increase of the time of residence in the North a tendency to greater individual differences in the results of the test with the use of nitrotetrazolium blue appeared, very low results being observed alongside very high ones. These facts indicate that under the extreme conditions prevailing in the arctic areas the reactivity of human neutrophils to bacterial stimulators is inhibited.
D000328:Adult; D001110:Arctic Regions; D001770:Blood Bactericidal Activity; D002452:Cell Count; D004731:Endotoxins; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D009580:Nitroblue Tetrazolium; D013997:Time Factors
D004731:Endotoxins; D009580:Nitroblue Tetrazolium
Funktsional'naia aktivnost' polinkulearov krovi po dannym reaktsii s nitrosinim tetrazoliem u zhiteleĭ Kraĭnego Severa.