[Effect of etimizol and propylnorantifein on myocardial respiratory enzymatic activity in a neurogenic lesion].
Studies on rabbits have shown that neurogenic injury to the myocardium induced by 3-hour electric stimulation of the aortic arch resulted in considerable changes in the activity of respiratory enzymes such as succinate dehydrogenase and cytochrome oxidase. Premedication of the animals with ethymisole and propylnorantipheine that stimulate energy metabolism in the central nervous system of animals has a protective action on the myocardial enzymes tested.
D000818:Animals; D009202:Cardiomyopathies / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D004734:Energy Metabolism / Q000187:drug effects; D004789:Enzyme Activation / Q000187:drug effects; D005042:Etimizol / Q000031:analogs & derivatives / Q000627:therapeutic use*; D006321:Heart / Q000187:drug effects*; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D010088:Oxidoreductases / Q000378:metabolism*; D011817:Rabbits; D013997:Time Factors
D007093:Imidazoles; C026619:propylnorantifein; D010088:Oxidoreductases; D005042:Etimizol
Vliianie etimizol i propilnorantifeina na aktivnost' dykhatel'nykh fermentov miokarda pri ego neĭrogennom porazhenii.