title: [Endocrine aspects of pathology of the upper portions of the gastrointestinal tract].
abstract: Light and electron microscopic studies of endocrine cells of the stomach, duodenum, and jejunum, and A-cells of the pancreatic gland of 657 patients with chronic gastritis, peptic ulcer, and postgastroresection complications revealed quantitative and qualitative differences in the conditions of the cells in these diseases. A certain relationship between the content of certain types of endocrine cells of the digestive organs and the acid-producing function of the stomach was found. Duodenal ulcer and peptic ulcer of the anastomosis appear to be characterized by an increase in the number of endocrine cells associated with stimulation of acid production, and by the presence of functionally poorly active cell forms participating in inhibition of this process. Chronic gastritis and post-resection complications seem to be associated with decreased presence of acid-stimulating endocrine cells and increase in the number of cells whose function is connected with inhibition of the gastric secretion.
mesh_terms: D000343:Afferent Loop Syndrome / Q000503:physiopathology; D002908:Chronic Disease; D004064:Digestive System / Q000503:physiopathology; D004377:Dumping Syndrome / Q000503:physiopathology; D004702:Endocrine Glands / Q000503:physiopathology*; D005753:Gastric Mucosa / Q000503:physiopathology; D005756:Gastritis / Q000503:physiopathology; D005767:Gastrointestinal Diseases / Q000503:physiopathology*; D006801:Humans; D008854:Microscopy, Electron; D010437:Peptic Ulcer / Q000503:physiopathology
vernacular_title: Endokrinnye aspekty patologii verkhnikh otdelov zhel udochnokishechnogo trakta.