title: Fate of the theca interna following ovulation in the ewe.
abstract: The fate of the theca interna after ovulation was studied in ewes, using light and electron microscopic histology and histochemistry. At the time of ovulation the theca interna was incorporated, apparently completely, into the margin of the developing corpus luteum and into the centres of many infoldings of the follicular wall. There was no evidence of degeneration of the more highly differentiated theca interna cells at or following the time of ovulation. Within 24 h of ovulation, cells derived from the theca interna began migrating from their original sites into the deeper, granulosa-derived areas of the luteal tissue. At later stages cells derived from the theca interna remained concentrated in septa derived from the follicular infoldings, but were also widely distributed throughout the luteal tissue. Structural evidence supported the view that the small luteal cells and fibroblasts of the corpus luteum were derived from the theca interna, and the large luteal cells from the membrana granulosa.
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D003338:Corpus Luteum / Q000166:cytology; D005260:Female; D006107:Granulosa Cells / Q000166:cytology; D009940:Organoids / Q000648:ultrastructure; D010060:Ovulation; D012756:Sheep / Q000033:anatomy & histology* / Q000502:physiology; D013799:Theca Cells / Q000166:cytology* / Q000201:enzymology
chemical_list: D000469:Alkaline Phosphatase