title: Nutrition in the Multiple Risk Factor Intervention Trial (MRFIT).
abstract: The Multiple Risk Factor Intervention Trial (MRFIT) is a clinical trial to determine whether primary prevention of coronary heart disease (CHD) is achievable. The main objective is to learn whether a special intervention program for men at increased risk of death from CHD can result in a significant reduction in mortality from this disease. For this investigation, 12,866 men, ages thirty-five to fifty-seven years, have been enrolled, after having been identified at increased risk because of a combination of risk factors: Elevated serum cholesterol, elevated diastolic blood pressure, and cigarette smoking. MRFIT provides an excellent opportunity for nutritionists to work closely with physicians, behavioral scientists, nurses, and other scientists in a program to change food habits, reduce blood pressure, and achieve cessation of smoking.
mesh_terms: D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009098:Multiphasic Screening; D011336:Probability; D012306:Risk; D000074606:Smoking Prevention
chemical_list: D002784:Cholesterol