Protein abnormalities in macrophages bearing asbestos.
Computerized techniques for the evaluation of O'Farrell two-dimensional electrophoretic gels have been applied to proteins derived from asbestos bearing macrophages. Preliminary results indicate definite changes in the protein content of cells depending on fiber phagocytosis.
D000818:Animals; D001194:Asbestos / Q000633:toxicity*; D001345:Autoradiography; D002460:Cell Line; D003201:Computers; D003720:Densitometry; D004586:Electrophoresis / Q000295:instrumentation / Q000379:methods; D005782:Gels; D008264:Macrophages / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D051379:Mice; D011506:Proteins / Q000378:metabolism*
D005782:Gels; D011506:Proteins; D001194:Asbestos