title: An interrupter method for measurement of airway resistance in small animals.
abstract: An interrupter technique for the measurement of airway resistance in spontaneously breathing, unanesthetized small experimental animals is described. The method makes use of an automatic 35-mm camera body to provide the necessary speed for interruption in these rapidly breathing animals and an analog computer to monitor breathing. The system was designed as a screening technique for assessing the irritancy of air pollutants. Initial results using rabbits is presented.
mesh_terms: D000403:Airway Resistance; D000818:Animals; D008168:Lung / Q000502:physiology; D012123:Pulmonary Ventilation; D011817:Rabbits