title: Tolerance of autosomal imbalance by the Syrian hamster (Mesocricetus auratus).
abstract: Cytogenetic and transmission data are given for a number of radiation-induced and spontaneous chromosomal changes which show that the Syrian hamster (Mesocricetus auratus) can tolerate a considerable amount of autosomal imbalance without phenotypic effect. It is suggested that the reason for this may lie in the very large amount of late-replicating chromatin present in this species.
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D002872:Chromosome Deletion; D006224:Cricetinae / Q000235:genetics*; D004261:DNA Replication; D004195:Disease Models, Animal; D005260:Female; D005298:Fertility; D006570:Heterochromatin; D008136:Longevity; D008297:Male; D008647:Mesocricetus / Q000235:genetics*; D009369:Neoplasms / Q000209:etiology; D010802:Phylogeny; D013997:Time Factors; D014178:Translocation, Genetic / Q000528:radiation effects
chemical_list: D006570:Heterochromatin