title: The effects of a megalevel of vitamin C on the immune response of the chicken.
abstract: Birds fed diets supplemented with 1% vitamin C experienced significant increases in serum levels of vitamin C. Cell-mediated immunity and antibody response to sheep red blood cells, a T-cell dependent antigen, were not influenced by feeding megalevels of vitamin C. However, the antibody response to a T-independent antigen, Brucella abortus, was lower in neonates and higher in adults in the presence of increased levels of vitamin C.
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D001205:Ascorbic Acid / Q000494:pharmacology*; D002645:Chickens / Q000276:immunology / Q000378:metabolism*; D007111:Immunity, Cellular / Q000187:drug effects*
chemical_list: D001205:Ascorbic Acid