Disseminated protothecosis with central nervous system involvement in a dog.
A 4-year-old mixed-breed spayed bitch was euthanatized after 2 1/2 months of progressive neurologic disease. Prototheca organisms were identified by histopathology, culture, and electron microscopy. Specific fluorescent antibody procedures revealed two species--Prototheca wickerhamii and Prototheca zopfii. Organisms and pyogranulomatous lesions were found in the brain, spinal cord, right eye, kidneys, and heart.
D000818:Animals; D001927:Brain Diseases / Q000473:pathology / Q000662:veterinary; D002493:Central Nervous System Diseases / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology / Q000473:pathology*; D004285:Dogs; D005128:Eye Diseases / Q000473:pathology / Q000662:veterinary; D005260:Female; D007239:Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary; D007674:Kidney Diseases / Q000473:pathology / Q000662:veterinary; D011525:Prototheca / Q000276:immunology / Q000302:isolation & purification; D013118:Spinal Cord Diseases / Q000473:pathology / Q000662:veterinary