Muscarinic cholinergic binding sites in an orthopteran central nervous system.
Homogenates of cricket (Acheta domesticus) central nervous system (CNS) specifically bind to potent muscarinic ligand [3H]-QNB. Binding assay and pharmacologic data indicate that the cricket CNS contains a high density of muscarinic cholinergic binding sites. These sites appear to be a unique class of invertebrate cholinergic receptor with properties distinct from those of previously described nicotinic receptors.
D000818:Animals; D009420:Nervous System / Q000378:metabolism*; D009987:Orthoptera / Q000378:metabolism*; D011813:Quinuclidinyl Benzilate / Q000378:metabolism; D011976:Receptors, Muscarinic / Q000378:metabolism
D011976:Receptors, Muscarinic; D011813:Quinuclidinyl Benzilate