[Population studies of hypertension in 2 populated areas].
A population-genetic study on the population of the mountainous villages, in the Rhodopes, was carried out, aiming at the elucidation of the incidence of hypertonic disease (HD), depending on the effect of hereditary factors and risk environmental factors. The values of systolic and diastolic arterial pressure among the population from both villages are distributed in Gauss--Laplacian curves, as a result from the effect of multiple poligens. In one of the villages, the mode of life of the population is considerably close to that of a modern town, hence the risk environmental factors, originated by technization and urbanization, have a stronger effect and as a consequence HD incidence observed is higher--10.05 per cent, whereas in the other village--in the absence of those factors--its incidence is 7.18 per cent. The same are the reasons, in the first village, that affect the females more often than the males (p less than 0.001) and a tendency is obvious for a considerable shift of the disease to an earlier age. In both villages a very low percentage of patients with HD were found that were insensitive to the bitter taste of phenylthiocarbamide.
D000017:ABO Blood-Group System / Q000235:genetics; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002031:Bulgaria; D005260:Female; D005828:Genetics, Population; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010671:Phenylurea Compounds; D012424:Rural Population
D000017:ABO Blood-Group System; D010671:Phenylurea Compounds
Populatsionni prouchvaniia na khipertonichnata bolest v dve naseleni mesta.