title: Constraints upon the composition of supplementary DNA.
abstract: Speciation in eukaryotes is often accompanied by massive changes in nuclear DNA amount resulting from the accumulation or deletion of DNA base sequences within chromosomes. Our evidence shows that, among related species, the DNA lost or gained during divergence is of a remarkably consistent and restricted composition in respect of the ratio of repetitive to non-repetitive base sequences. It is argued that the restriction may in part at least be imposed by natural selection, in the sense that the only changes tolerable are confined to DNA fractions of particular composition and organisation.
mesh_terms: D000663:Amphibians / Q000235:genetics; D000818:Animals; D001483:Base Sequence; D002467:Cell Nucleus / Q000032:analysis; D001517:Coleoptera / Q000235:genetics; D004247:DNA; D008974:Mollusca / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010802:Phylogeny; D010944:Plants / Q000235:genetics; D006109:Poaceae / Q000235:genetics; D012377:Rodentia / Q000235:genetics
chemical_list: D004247:DNA