title: [Post-radiation injury of the ileal small bowel: clinical and pathological report of 12 cases (author's transl)].
abstract: At the Institut Gustave-Roussy we have collected a series of 12 cases studied both on clinical and patological grounds. These patients underwent ileal resection for acute abdominal symptoms occuring after radiation therapy for genital cancer. Ileal lesions after radiation of gynecological cancer are rare: one per cent at the Institut Gustave-Roussy. These complications occur when certain technical types of radiation therapy are employed, and especially when dose exceeds 50 Gy or when a particular clinical condition is present. Gross examination of the bowel segment shows a stiffness of the digestive wall with frequent stenosis, sometimes in association with perforation or fistula. Histological lesions of radiated bowel are essentially located in the submucosa. They are nonspecific, mainly represented by obliterative angiopathy and fibrosis of the ileal wall.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007082:Ileum / Q000293:injuries* / Q000473:pathology; D007415:Intestinal Obstruction / Q000175:diagnosis / Q000209:etiology; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy
vernacular_title: Lésions iléales graves post-irradiation. A propos de 12 observations anatomo-cliniques.