Oncocytic carcinoid tumor of the lung.
We report a bronchial tumor composed of a mixture of oncocytes and carcinoid tumor cells; the latter formed ribbons and pseudoglandular structures in the fashion of a carcinoid tumor. Ultrastructurally, the oncocytic cells showed large numbers of mitochondria but no neurosecretory granules. Although the stem cell of the pulmonary K-cell is unknown, our findings support the notion that both the pulmonary endocrine cells and the oncocytes arise from it.
D000236:Adenoma / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D001980:Bronchi / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008928:Mitochondria / Q000473:pathology; D009361:Neoplasm Invasiveness