title: Drug therapy in renal failure: dosing guidelines for adults. Part II: sedatives, hypnotics, and tranquilizers; cardiovascular, antihypertensive, and diuretic agents; miscellaneous agents.
abstract: Data providing guidelines for drug use in adult patients with renal insufficiency are presented in tabular form with supporting references. The data are derived from the current medical literature. If specific information about a drug is unavailable or conflicting, emphasis is given to normal pharmacokinetic variables in arriving at recommendations for therapy. Nephrotoxicity or adverse effects in patients with renal disease are noted and adjustments for dialysis suggested.
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D004232:Diuretics / Q000008:administration & dosage*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007676:Kidney Failure, Chronic / Q000188:drug therapy* / Q000628:therapy; D007700:Kinetics; D006435:Renal Dialysis; D014149:Tranquilizing Agents / Q000008:administration & dosage*
chemical_list: D000959:Antihypertensive Agents; D002317:Cardiovascular Agents; D004232:Diuretics; D006993:Hypnotics and Sedatives; D014149:Tranquilizing Agents