title: Mixed connective tissue disease with associated glomerulonephritis and hypocomplementaemia.
abstract: Mixed connective tissue disease is an increasingly recognized entity in which renal disease is thought to be unusual and associated hypocomplementaemia even more uncommon. A patient is described who had both these features and who also illustrates many of the characteristic features of this syndrome. The response to steroids of the systemic sclerosis component is well shown and an additional feature of interest is the family history of other connective tissue diseases.
mesh_terms: D000328:Adult; D003165:Complement System Proteins / Q000172:deficiency*; D005260:Female; D005921:Glomerulonephritis / Q000150:complications*; D006801:Humans; D008947:Mixed Connective Tissue Disease / Q000150:complications*
chemical_list: D003165:Complement System Proteins