[Regional cytostatic infusion therapy in patients with inoperable gastrointestinal carcinomas and metastases in the liver (author's transl)].
Report on 50 patients with incurable gastrointestinal carcinoma and 8 patients with metastases in the liver who received a regional transarterial continuous infusion therapy with 1 g 5-Fluorouracil daily for a period of 5 to 6 days. A clinically demonstrable remission for a period of 6 to 15 months occurred in 76% of the patients. The treatment which is administered in intervals of 6 to 8 weeks is well tolerated and the incidence of complications is low. Therefore this method may be recommended for otherwise completely incurable gastrointestinal carcinomas.
D000328:Adult; D000368:Aged; D010478:Chemotherapy, Cancer, Regional Perfusion; D003125:Colostomy; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D005770:Gastrointestinal Neoplasms / Q000188:drug therapy*; D006801:Humans; D007415:Intestinal Obstruction / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary*; D008875:Middle Aged
D005472:Fluorouracil
Die regionale zytostatische Infusionsbehandlung bei inoperablen gastrointestinalen Karzinomen und bei Metastasenleber unter spezieller Berücksichtigung des Rektumkarzinoms.