title: Induction of labour with vaginal prostaglandin E2 pessaries.
abstract: Wax-based pessaries, each containing 3 mg of prostaglandin E2 (PGE2), were administered intravaginally for the induction of labour. The induction to delivery intervals were shorter than those in a control group induced by amniotomy and intravenous oxytocin. There was a remarkable reduction in the Caesarean section rate from 12 per cent in the control group to 2.4 per cent in the study group in primiparae, and from 8 per cent to 1.6 per cent in multiparae. Side effects associated with the PGE2 were rare, as were complications.
mesh_terms: D000328:Adult; D001034:Apgar Score; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D010298:Parity; D010570:Pessaries; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014621:Vagina
chemical_list: D011458:Prostaglandins E