Angiotensin and drinking rates in the euryhaline killifish.
Drinking rates were measured in the euryhaline fish Fundulus heteroclitus in the presence and absence of angiotensin II or its competitive inhibitor P-113 and converting enzyme inhibitor (SQ20881). Angiotensin stimulated drinking in Fundalus adapted to salt- or freshwater. More significant, P-113 decreased drinking rates in saltwater-adapted fish and to ones acutely exposed to saltwater. SQ20881 was also effective in inhibiting drinking. These data are interpreted to support the hypothesis that endogenously produced angiotensin is a physiological stimulus for drinking in fish.
D000222:Adaptation, Physiological; D000804:Angiotensin II / Q000031:analogs & derivatives* / Q000494:pharmacology*; D000818:Animals; D004327:Drinking Behavior / Q000502:physiology*; D005399:Fishes / Q000502:physiology*; D007695:Killifishes / Q000378:metabolism / Q000502:physiology*; D012504:Saralasin / Q000494:pharmacology*; D012623:Seawater; D014867:Water / Q000378:metabolism
D014867:Water; D000804:Angiotensin II; D012504:Saralasin