Occupational scleroderma-like disorder occurring in men engaged in the polymerization of epoxy resins.
A new occupational disorder characterized by skin sclerosis is described. This disease developed acutely in workmen exposed to the vapor of epoxy resins. Based on animal experiments, an amine [bis(4-amino-3-methyl-cyclohexyl) methane] is suspected of being the causative agent of the skin sclerosis.
D000328:Adult; D003514:Cyclohexylamines / Q000633:toxicity; D004853:Epoxy Resins / Q000633:toxicity*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009784:Occupational Diseases / Q000139:chemically induced*; D011108:Polymers; D012595:Scleroderma, Systemic / Q000139:chemically induced*; D012598:Sclerosis; D012867:Skin / Q000473:pathology; D014752:Vinyl Chloride / Q000633:toxicity
D003514:Cyclohexylamines; D004853:Epoxy Resins; D011108:Polymers; D014752:Vinyl Chloride