[Genetic-metabolic model of cancer cell behavior].
It is suggested that the transforming protein (type pp60) induce "insulinization" of the cell membrane. It is mostly due to this effect that the cell sensitivity to insulin and insulin-like factors of the body internal medium is enhanced, which in turn results in the increased glucosa transport into cell. The transforming protein is also supposed to increase the activity of the glycolysis key enzymes by phosphorylating them. The presence of these two effects seems to be sufficient enough to explain "the biochemical behaviour" of the cancerous cell.
D002462:Cell Membrane / Q000201:enzymology; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D005814:Genes, Viral; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis; D006801:Humans; D008954:Models, Biological; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D012190:Retroviridae / Q000201:enzymology / Q000235:genetics
D011494:Protein Kinases; D005947:Glucose
Genno-metabolicheskaia model' povedeniia rakovoĭ kletki.