Ticarcillin concentrations in serum, muscle, and fat after a single intravenous injection.
Ticarcillin concentrations in serum, muscle, and fat were determined simultaneously in 23 patients after the intravenous injection of a single dose of 5 g. The mean concentrations of ticarcillin in serum, muscle, and fat were, respectively, 185 microgram/ml, 18 microgram/g, and 32 microgram/g at 1.0 to 1.5 h after the injections, declining to levels of 11 microgram/ml, 2 microgram/g at 6 to 7 h after the injections. There was no significant difference between the serum tissue ratios at these time periods.
D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*; D010406:Penicillins / Q000378:metabolism*; D013982:Ticarcillin / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D013997:Time Factors; D014018:Tissue Distribution
D010406:Penicillins; D013982:Ticarcillin