Normal human endometrium in cell culture. III. Mechanism(s) of epithelial polyploidization.
Autoradiography has confirmed previous cytophotometric results showing epithelial polyploid formation to be dependent on DNA synthesis. Polyploidization appears to be largely caused by endoreduplication and perhaps, to a lesser extent, by failure of cytokinesis.
D000328:Adult; D000782:Aneuploidy; D001345:Autoradiography; D002467:Cell Nucleus / Q000378:metabolism; D002478:Cells, Cultured / Q000166:cytology; D004247:DNA / Q000096:biosynthesis; D004261:DNA Replication; D004717:Endometrium / Q000166:cytology*; D004847:Epithelial Cells; D005260:Female; D006801:Humans; D008938:Mitosis; D011123:Polyploidy
D004247:DNA