Persistent measles virus infection in a calf kidney cell line. Note IV. Electron microscopic observations in the K-2 cell line.
An electron microscopic study was performed in the K-2 calf kidney cell line persistently infected with measles virus. Aggregates of granular filamentous structures 20-30 nm in diameter were detected in the paranuclear zone of the cytoplasm. Rare, isolated smooth filaments 15-17 nm in diameter were also observed. No such structures were seen in the nucleus. The budding process was very active. Many pleomorphic particles ranging in diameter from 100 to 600 nm were observed at the cell surface and in the intercellular space; the particles contained a variable amount of filamentous nucleocapsid structures and had an envelope with discontinuous fuzzy material.
D000818:Animals; D002417:Cattle; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D007668:Kidney; D008459:Measles virus / Q000254:growth & development / Q000648:ultrastructure*; D008854:Microscopy, Electron; D014776:Virus Cultivation