[Effect of carboxylin and sodium citrate on the content of intermediate products of tricarboxylic cycle, free amino acids and urea in rabbit tissues in alloxan diabetes].
Feeding carboxylin and sodium citrate to rabbits with alloxane diabetes, normalizes the disturbed contents of malate, alpha-ketoglutarate, oxaloacetate, citrate and pyruvate in the blood and liver of these animals restores the total content of alpha-keto-and free amino acids, increases considerably the urea content in the liver.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology*; D002951:Citrates / Q000378:metabolism / Q000494:pharmacology*; D002952:Citric Acid Cycle / Q000187:drug effects*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D004338:Drug Combinations / Q000494:pharmacology; D007656:Ketoglutaric Acids / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008293:Malates / Q000378:metabolism; D008670:Metals / Q000494:pharmacology*; D010071:Oxaloacetates / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D011817:Rabbits; D017693:Sodium Bicarbonate; D014508:Urea / Q000378:metabolism*
D000596:Amino Acids; D001639:Bicarbonates; D002951:Citrates; D004338:Drug Combinations; D007656:Ketoglutaric Acids; D008293:Malates; D008670:Metals; D010071:Oxaloacetates; D011773:Pyruvates; D000644:Quaternary Ammonium Compounds; C006905:ammonium, magnesium, manganese, sodium bicarbonate, zinc sulfate drug combination; D017693:Sodium Bicarbonate; D014508:Urea
Vliianie karboksilina i limonnokislogo natriia na soserzhanie promezhutochnykh produktov trikarbonovogo tsikla svobodnykh aminokislot i mocheviny v tkaniakh krolikov pri alloksanovom diabete.