Pathologic interactions between prosthetic aortic grafts and the gastrointestinal tract. Clinical problems and a new experimental approach.
Twenty-one patients presented with pathologic interactions between the gastrointestinal tract and aortic grafts. Seventeen patients were managed by excision of the graft and axillobifemoral bypass. Six patients died. four deaths were due to disruption of the proximal aortic stump after initial therapy that appeared successful. An experimental model of a seromuscular jejunal patch is presented that may be beneficial for closure of the proximal aortic stump.
D000818:Animals; D001011:Aorta / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004195:Disease Models, Animal; D004285:Dogs; D006801:Humans; D007239:Infections / Q000209:etiology; D007412:Intestinal Fistula / Q000209:etiology* / Q000473:pathology; D007583:Jejunum / Q000601:surgery; D013524:Surgical Flaps