Melphalan-induced pulmonary interstitial fibrosis.
Diffuse interstitial fibrosis developed in a patient receiving therapy with melphalan for multiple myeloma. With cessation of the administration of the alkylating agent and corticosteroid, we describe progressive radiographic improvement in this patient, accompanied by persistent severe impairment in gas exchange.
D005260:Female; D006801:Humans; D008558:Melphalan / Q000009:adverse effects*; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy
D008558:Melphalan; D011241:Prednisone