[Short-term therapy of atrial fibrillation with an association of digitalis and amiodarone (author's transl)].
Forty patients with organic cardiopathies and permanent atrial fibrillation were divided at random into two similar groups in relation to their diagnoses and ages. Twenty patients were treated with digoxine alone, and the other 20 with digoxine plus amiodarone hydrochloride. Comparison of results from each group showed statistical significant differences (p less than 0.0005) regarding total digoxine dosage and length of treatment. Mechanism of action of this synergia is discussed, and the association of digitalis and amiodarone is recommended to reduce digitalization time in patients with paroxysmal auricular tachycardia.
D000328:Adult; D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D001572:Benzofurans / Q000627:therapeutic use*; D004071:Digitalis Glycosides / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D001572:Benzofurans; D004071:Digitalis Glycosides; D000638:Amiodarone
Asociación de la digital y la amiodarona en el tratamiento a corto plazo de la fibrilación auricular.