The effects of polymer-solvent compositions on the formation of collodion membrane artificial cells.
This study is an attempt to analyze the various polymer-solvent compositions for preparing collodion membrane artificial cells for biomedical applications. Cellulose nitrate was disolved in different mixtures of alcohol-ether solutions and used for microencapsulation. The most optimal solvent solution consisted of 4 g% cellulose nitrate in 17.5% (volume) alcohol and 82.5% (volume) ether. The urease microcapsules prepared this way showed no leakage of enzyme under test conditions. Having established the optimal polymer-solvent compositions, an easier and more reproducible procedure has been established for preparing collodion membrane artificial cells.
D002214:Capsules; D003101:Collodion; D003102:Colloids; D004800:Enzymes, Immobilized; D000431:Ethanol; D004986:Ether; D005019:Ethyl Ethers; D008567:Membranes, Artificial; D011108:Polymers; D012997:Solvents; D014510:Urease
D002214:Capsules; D003102:Colloids; D004800:Enzymes, Immobilized; D005019:Ethyl Ethers; D008567:Membranes, Artificial; D011108:Polymers; D012997:Solvents; D004986:Ether; D000431:Ethanol; D003101:Collodion; D014510:Urease