title: [Electron microscopic diagnostic problems in human fibroblastic tumors].
abstract: The ultrastructure of 17 fibroblastic tumors in man has been studied. As a result, there was revealed a complex of features which might aid the electron-microscopic differential diagnosis of the neoplasms concerned: large cells with heavy cytoplasmatic processes; wide intercellular spaces which contain a specific fibrillar and granular fibrillar material; cellular nuclei sections show a typical irregular pattern represented in two variants. The intercellular fibrillar apparatus is specific enough with respect to the filaments structure, their aggregation and localization; also typical is the presence of an extensive system of granular endoplasmatic reticulum in cytoplasm. It is emphasized that the absence of some structures characteristic of other neoplasms: basal membrane, desmosomes, specific secretory granules etc. is of great importance for diagnosing such kind of tumors.
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003581:Cytodiagnosis / Q000379:methods; D003593:Cytoplasm / Q000648:ultrastructure; D005350:Fibroma / Q000175:diagnosis* / Q000648:ultrastructure; D005354:Fibrosarcoma / Q000175:diagnosis* / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron
vernacular_title: Nekotorye voprosy élektronno-mikroskopicheskoui diagnostiki fibroblasticheskikh opukholeĭ cheloveka.