title: Atenolol 4% eyedrops in glaucoma simplex.
abstract: The single-dose response to local administration of atenolol 4% is compared in normal eyes and 3 groups of eyes with glaucoma simplex. The reduction in intraocular pressure is seen to be greater in eyes with glaucoma than in normal eyes. The usefulness of atenolol 4%, whether or not combined with other local therapy, seems to be limited by tachyphylaxis.
mesh_terms: D001262:Atenolol / Q000008:administration & dosage* / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions; D010276:Parasympatholytics / Q000008:administration & dosage; D011412:Propanolamines / Q000008:administration & dosage*; D013566:Sympathomimetics / Q000008:administration & dosage; D013618:Tachyphylaxis; D013997:Time Factors
chemical_list: D009883:Ophthalmic Solutions; D010276:Parasympatholytics; D011412:Propanolamines; D013566:Sympathomimetics; D001262:Atenolol