A rare blood group antigen, R1a (Rosenlund).
A 'new rare blood group antigen R1a (Rosenlund) is reported. The antigen is present in about 1 in 900 Norwegians. Nine unrelated R1(a+) people were found. Studies of seven families, leading to the discovery of 20 additional R1(a+) people, indicated the antigen is inherited as a Mendelian dominant character. Independent segregation was demonstrated between Rla and the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems, the ABH secretor genes, and sex. The R1a antigen is inactivated by papain treatment. The corresponding antibody, anti-R1a, has so far been found in three sera that also contain antibodies to other rare blood group antigens.
D001789:Blood Group Antigens / Q000235:genetics*; D006801:Humans; D009664:Norway
D001789:Blood Group Antigens