title: Xenon arc photocoagulation for the treatment of diabetic maculopathy. Interim report of a multicentre controlled clinical study.
abstract: The results of a randomised controlled clinical study in the treatment of diabetic maculopathy are reported. Ninety-nine patients with two similarly affected eyes had one--chosen by random procedure--treated, while the other was left as an untreated control. Visual acuity was maintained in the treated eyes, while it deteriorated in the untreated eyes, reaching over 2 lines difference after 4 years. The difference in deterioration was significantly less in treated than in untreated eyes at each assessment. After 4 years the difference between the 2 eyes was greatest in those with initially good vision. There was no difference in visual acuity in patients whose initial vision was less than 6/36. Only 9 treated but 25 control eyes lost vision to blindness (P less than 0.001). It is concluded that maculopathy is a treatable form of diabetic retinopathy if treated before severe visual loss occurs.
mesh_terms: D000328:Adult; D000368:Aged; D003201:Computers; D003930:Diabetic Retinopathy / Q000601:surgery*; D006801:Humans; D008028:Light Coagulation; D008266:Macula Lutea; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D014792:Visual Acuity