Heritable fragile sites on human chromosomes. V. A new class of fragile site requiring BrdU for expression.
A new fragile site at 10q25 is described, representing a new class of fragile site that requires bromodeoxyuridine (BrdU) in the culture medium for expression. This new fragile site is present in approximately one in 30 of the Australian population; it has only been observed in heterozygotes.
D001973:Bromodeoxyuridine / Q000494:pharmacology*; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X / Q000648:ultrastructure*; D003470:Culture Media; D006579:Heterozygote; D006801:Humans; D010375:Pedigree; D011110:Polymorphism, Genetic
D003470:Culture Media; D001973:Bromodeoxyuridine