title: Proliferative glomerulonephritis with crescent formation in behcet's syndrome.
abstract: Behcet's syndrome is a multisystem disease complex, the major manifestions of which are oral and genital ulcers, arthritis, uveitis, and skin eruptions. Less frequently, CNS disturbances, colitis, thrombophlebitis, large-vessel vaculitis, and myocarditis occur. If renal involvement does occur, it is usually manifested by asymptomatic microhematuria and/or proteinuria. Recently, renal amyloidosis and focal necrotizing glomerulonephritis with immune complex deposition have been described. We describe a patient with Behcet's syndrome who experienced diffuse proliferative glomerulonephritis with epithelial cell crescent formation in 75% of glomeruli examined. Immune complexes were not identified. Renal function, impaired on admission, improved with no therapy.
mesh_terms: D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008875:Middle Aged