title: [Orthograde intestinal irrigation as a preoperative intestinal preparation. Reduction of the intestinal flora using antibiotics].
abstract: Whole gut irrigation is a now a well-established method of preoperative bowel preparation. Additional reduction of bacterial content is desirable. The influence of neomycin/bacitracin and clindamycin as well as the combination, as admixture to the whole gut irrigation, on the flora of the large intestine, was therefore investigated in a prospective controlled study. While neomycin/bacitracin caused only a reduction of aerobic, and clindamycin of the anaerobic bacteriae, the combination resulted in a nearly total eradication of detectable bacterial content at the time of operation.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001414:Bacitracin / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D003106:Colon / Q000382:microbiology* / Q000601:surgery; D004357:Drug Synergism; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D009355:Neomycin / Q000008:administration & dosage; D011300:Preoperative Care; D007507:Therapeutic Irrigation / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D001414:Bacitracin; D002981:Clindamycin; D009355:Neomycin
vernacular_title: Orthograde Darmspülung zur präoperativen Darmvorbereitung. Reduktion der Darmflora durch Antibioticazusatz.