A new white forelock (poliosis) syndrome with multiple congenital malformations in two sibs.
Two Jewish Ashkenazi male sibs are reported as having a new syndrome consisting of a white forelock, distinct facial features associated with congenital malformations involving the eye, cardio-pulmonary and skeletal systems. It is postulated that the etiology of this disorder is genetic and transmitted either as an autosomal recessive or X-linked recessive conditions.
D000015:Abnormalities, Multiple / Q000235:genetics*; D002675:Child, Preschool; D005808:Genes, Recessive; D006200:Hair Color; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree; D013577:Syndrome