[Effect of fats in diets with a varying degree of fatty acid saturation on aspects of lipid metabolism].
Distribution of lipids in the liver, blood and bile, and rates of their elimination with the bile were studied in rats fed with diets having an elevated proportion of lard or sunflower oil. High fat diet including lard was conducive to an increase in the content and radioactivity of triglycerides and cholesterol esters in the liver tissue. Lipid concentration in the blood and bile was not different from control values, while the bile showed less amount of the label incorporated in phospholipids and cholesterol. The diet including the increased levels of sunflower oil produced a rise in the content and radioactivity of triglycerides, ester bound and free cholesterol in the liver. The concentration and radioactivity of triglycerides in the blood dropped. The content of cholic acid and cholesterol in the bile rose with a simultaneous increase in the amount of the label incorporated into phospholipids and cholesterol.
D000818:Animals; D001646:Bile / Q000378:metabolism; D004041:Dietary Fats / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005227:Fatty Acids / Q000494:pharmacology*; D006368:Helianthus; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009821:Oils / Q000494:pharmacology; D051381:Rats; D013552:Swine
D004041:Dietary Fats; D005227:Fatty Acids; D009821:Oils
Vliianie zhirov v ratsionakh s razlichnoĭ stepen'iu nasyshchennosti zhirnykh kislot na nekotorye storony metabolizma lipidov.