Comparison of plasma levels and excretory routes between No. 189 and No. 407, potent thrombin inhibitors.
D000284:Administration, Oral; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D004151:Dipeptides / Q000378:metabolism / Q000494:pharmacology*; D004285:Dogs; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D008099:Liver / Q000378:metabolism; D008297:Male; D010880:Piperidines / Q000378:metabolism / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D013449:Sulfonamides / Q000378:metabolism / Q000494:pharmacology*; D013917:Thrombin / Q000037:antagonists & inhibitors*
D004151:Dipeptides; D010880:Piperidines; D013449:Sulfonamides; C011211:dansyl-arginine-methylpiperidine amide; C025535:No. 407; D001120:Arginine; D013917:Thrombin