Effect of levamisole on skin reactions to DNCB in chronically dialyzed patients.
The local cutaneous inflammatory response to DMCB sensitization was positive in only 35% of 20 uremic patients, and the delayed skin reaction was positive in only 15%. The reaction to DMCB challenge was markedly delayed in some patients. Improved response to DNCB re-challenge followed levamisole administration in only 16% of the patients and was not associated with a rise in blood lymphocytes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003877:Dermatitis, Contact / Q000209:etiology / Q000276:immunology; D004137:Dinitrochlorobenzene / Q000276:immunology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology / Q000276:immunology*; D007978:Levamisole / Q000494:pharmacology*; D008875:Middle Aged; D009578:Nitrobenzenes / Q000276:immunology*; D006435:Renal Dialysis; D012867:Skin / Q000276:immunology*; D012882:Skin Tests; D014511:Uremia / Q000276:immunology / Q000628:therapy
D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes; D007978:Levamisole