title: Distant metastases of carcinoma of tonsillar region: a study of 475 patients.
abstract: The records of 471 patients with carcinoma of the tonsillar region seen at the Veterans Administration Medical Center, Hines, Illinois, have been reviewed to determine the incidence and location of distant metastases. All patients were male and with histologically proved diagnosis. Seventy-two patients (15%) of 471 and 33(29%) of 115 patients who underwent autopsy were found to have distant metastases. Squamous cell carcinoma was by far the most common cell type (88%); however lymphoepithelioma showed the highest incidence of distant metastases. Lung, liver, and bone were the most common anatomical sites of involvement, and thorough work-up of these organs is highly recommended before initiating definitive treatment and during follow-up care.
mesh_terms: D001859:Bone Neoplasms / Q000556:secondary; D002277:Carcinoma / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000556:secondary; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D009362:Neoplasm Metastasis / Q000473:pathology*; D014067:Tonsillar Neoplasms / Q000473:pathology*