title: [Wilson's disease in the German Democratic Republic. II. Pathogenesis and clinical aspects].
abstract: From the point of view of the Leipzig Centre for Wilson's disease in the GDR the authors adopt a definite attitude to the questions of pathogenesis and clinic. Since for the performance of the life-saving long-term therapy the disease must be diagnosed early, in detail are described the preclinical (asymptomatic) and clinical stage--including its various forms of manifestation--and their differential diagnosis and it is dealt with the changed radio-copper-kinetics.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002570:Ceruloplasmin / Q000172:deficiency; D002648:Child; D002675:Child, Preschool; D003300:Copper / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D006527:Hepatolenticular Degeneration / Q000145:classification / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007223:Infant; D008099:Liver / Q000503:physiopathology; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology; D014018:Tissue Distribution
chemical_list: D003300:Copper; D002570:Ceruloplasmin
vernacular_title: Untersuchungen zur Wilsonschen Erkrankung in der DDR. Teil II: Pathogenese und Klinik.