Myasthenia gravis, premature menopause, and thyroid autoimmunity.
Two case reports of patients with myasthenia gravis, premature menopause at ages 18 and 29 years, and evidence of thyroid and ovarian autoimmunity are presented. Both patients had elevated gonadotropins, sex steroid values in the menopausal range, and ovaries without follicular activity. An autoimmune etiology is suggested because of the high titers of antithyroid and antiovarian antibodies.
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008593:Menopause; D008594:Menopause, Premature; D009157:Myasthenia Gravis / Q000150:complications / Q000276:immunology*; D010053:Ovary / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology
D001323:Autoantibodies; D006728:Hormones; D007136:Immunoglobulins