title: Blood and brain aluminium concentrations in mice after intra-pertioneal injection of different aluminium compounds.
abstract: Aluminium chloride, nitrate, lactate and gluconate was injected by intraperitoneal route to mice at equimolecular doses, equivalent to 54 and 5.4 mg/kg of metal. The blood aluminium concentrations were increased to very high values with gluconate (99.5 mg/l) to high values with lactate (4.5 mg/l) and to low values with nitrate and chloride (0.3 mg/l). Brain aluminium concentration was increased only with glutconate at the dose of 54 mg/kg. The quantity of aluminium found in blood and brain after intraperitoneal administration at equimolecular doses is very dependent of the preparation of aluminium used.
mesh_terms: D000535:Aluminum / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism; D005942:Gluconates / Q000378:metabolism; D007274:Injections, Intraperitoneal; D007773:Lactates / Q000378:metabolism; D008297:Male; D051379:Mice; D009566:Nitrates / Q000378:metabolism
chemical_list: D002712:Chlorides; D005942:Gluconates; D007773:Lactates; D009566:Nitrates; D000535:Aluminum