19-norandrost-4-ene-3, 17-dione amplifies the action of aldosterone only in sodium-loaded conditions: evidence for a new class of amplifiers of aldosterone.
D000315:Adrenalectomy; D000450:Aldosterone / Q000494:pharmacology*; D000735:Androstenedione / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D004357:Drug Synergism; D004963:Estrenes / Q000494:pharmacology*; D008297:Male; D009318:Natriuresis / Q000187:drug effects*; D011188:Potassium / Q000652:urine; D051381:Rats; D012964:Sodium / Q000494:pharmacology
D004963:Estrenes; D000735:Androstenedione; D000450:Aldosterone; D012964:Sodium; D011188:Potassium; C002828:19-norandrostenedione