Determination of extractable mirex in whole blood.
A method for the determination of free mirex in blood has been developed in which whole blood is extracted with acetone-hexane (9+91), passed through Na2SO4, concentrated, and analyzed by electron capture gas-liquid chromatograpohy (GLC). Results were highest for fresh blood. Recoveries were verified by determining 14C-labeled mirex before and after extraction. Little mirex was detected in the samples after extraction. Hydrolysis of residual blood indicates that a metabolite of mirex is released. The possible metabolite has a GLC retention time and mass spectrum which resemble hydroxy metabolites of mirex.
D000818:Animals; D001345:Autoradiography; D002250:Carbon Radioisotopes; D002417:Cattle; D002645:Chickens; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D007306:Insecticides / Q000097:blood*; D008917:Mirex / Q000097:blood*; D011817:Rabbits
D002250:Carbon Radioisotopes; D007306:Insecticides; D008917:Mirex