[Antibiotic prophylaxis in colon surgery with Cefazolin].
In a prospective randomized and controlled double-blind trial the effect of prophylactic systemic administration of Cefazolin in elective colorectal surgery on postoperative wound infection was investigated. The incidence of wound infection was significantly reduced (P less than 0.01) from 32% in the control group to 10% in the treated group. Furthermore there was a significant reduction (P less than 0.05) in hospital stay of about 3 days.
D002437:Cefazolin / Q000627:therapeutic use*; D003106:Colon / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002437:Cefazolin
Antibiotikaprophylaxe in der Kolonchirurgie mit Cefazolin.