Enflurane has no effect on haemopoiesis in mice.
Male and female Swiss/ICR mice were exposed to 0.3% enflurane in air, 4 h per day, 5 days per week for 52 weeks. A control group was exposed to air alone. After 52 weeks, all animals were sacrificed and peripheral blood and bone marrow samples were examined for alterations in haemopoiesis. In general, there was no difference between treated and control groups.
D000818:Animals; D001772:Blood Cell Count; D001835:Body Weight; D004737:Enflurane / Q000494:pharmacology*; D004909:Erythrocyte Indices; D005260:Female; D006400:Hematocrit; D006410:Hematopoiesis / Q000187:drug effects*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D013997:Time Factors
D004737:Enflurane