title: The effect of diet and fasting on gallbladder opacification during oral cholecystography in dogs as measured by computed tomography.
abstract: To determine the influence of diet and fasting on gallbladder opacification during oral cholecystography, 10 dogs were studied in a blind, random fashion, giving single or two consecutive doses of iopanoic acid, sodium tyropanoate, or sodium ipodate while the animals were fasting, on a normal diet, or on a low-fat diet. Gallbladder density was determined by CT to eliminate the bias created by subjective interpretation of radiographs. For maximum, first-dose gallbladder opacification during clinical cholecystography, iopanoic acid should be given with a meal and sodium ipodate while the patient is fasting; diet makes no difference with sodium tyropanoate. For maximum opacification with two consecutive doses, iopanoic acid may be given with a meal or during fasting, while sodium ipodate and sodium tyropanoate should be administered during fasting.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002765:Cholecystography / Q000379:methods*; D003287:Contrast Media / Q000008:administration & dosage*; D004032:Diet; D004285:Dogs; D005215:Fasting; D007462:Iodobenzenes / Q000008:administration & dosage*; D007480:Iopanoic Acid / Q000008:administration & dosage; D007487:Ipodate / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D014441:Tyropanoate / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D007462:Iodobenzenes; D014441:Tyropanoate; D007487:Ipodate; D007480:Iopanoic Acid