title: Antitumor agents from bohemic acid complex, III. The isolation of marcellomycin, musettamycin, rudolphomycin, mimimycin, collinemycin, alcindoromycin, and bohemamine.
abstract: Six anthracycline antitumor agents, marcellomycin, musettamycin, rudolphomycin, alcindoromycin, collinemycin, and mimimycin, have now been isolated from bohemic acid complex. This has been achieved by classical column chromatography with Sephadex LH-20 and ammonia-neutralized silica and by analytical and prepatative hplc techniques with normal phase systems containing aqueous ammonia.
mesh_terms: D000818:Animals; D018943:Anthracyclines; D000900:Anti-Bacterial Agents / Q000032:analysis*; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000494:pharmacology; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D005260:Female; D007939:Leukemia L1210 / Q000188:drug therapy; D008297:Male; D008545:Melanoma / Q000188:drug therapy; D051379:Mice; D008826:Microbial Sensitivity Tests; D009279:Naphthacenes / Q000032:analysis* / Q000302:isolation & purification* / Q000494:pharmacology; D009374:Neoplasms, Experimental / Q000188:drug therapy; D011763:Pyrrolizidine Alkaloids / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D018943:Anthracyclines; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; D011763:Pyrrolizidine Alkaloids; C015338:marcellomycin; C015374:musettamycin; C015039:bohemic acid complex; C021739:rudolfomycin; C025546:alcindoromycin; C025545:collinemycin; C025548:bohemamine