Neutropenic enterocolitis and Clostridium septicum infection in patients with agranulocytosis.
Two patients with previously undiagnosed agranulocytosis had rapidly fatal Clostridium septicum sepsis and neutropenic enterocolitis. This toxigenic organism has a known predilection for cecal lesions. The association reported herein suggests that C septicum may be the cause of this necrotizing enteropathy.
D000293:Adolescent; D000380:Agranulocytosis / Q000150:complications* / Q000209:etiology*; D003015:Clostridium Infections; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D009503:Neutropenia / Q000209:etiology*; D018805:Sepsis / Q000150:complications*