title: An OCT-reactivity classification to predict fetal outcome.
abstract: Based on analyses of the oxytocin challenge test (OCT) in 293 cases, an OCT-reactivity classification is proposed to improve the predictive value of OCT for fetal outcome. All of the 6 perinatal deaths occurred in the 2 groups associated with nonreactive pattern. The positive nonreactive test had 90% accuracy of predicting a sick infant, and the negative reactive test assured good fetal outcome. A nonreactive pattern seems to reflect a compromised fetus, as a high incidence of this pattern was found in patients with pre-eclampsia-hypertension, intrauterine growth retardation (IUGR), low and falling estriol levels, and suspected fetal problems. A positive OCT seems to reflect the limits of fetoplacental reserve under the stressed condition. A high incidence of positive OCT was associated with IUGR, low estriol levels, and a small placenta.
mesh_terms: D000328:Adult; D001724:Birth Weight; D004964:Estriol / Q000652:urine; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005318:Fetal Heart / Q000502:physiology*; D005323:Fetal Monitoring; D005333:Fetus / Q000033:anatomy & histology; D005865:Gestational Age; D006339:Heart Rate; D006801:Humans; D009929:Organ Size; D010121:Oxytocin; D010920:Placenta / Q000033:anatomy & histology; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013312:Stress, Physiological
chemical_list: D010121:Oxytocin; D004964:Estriol