title: [Postinfection immunity in melioidosis].
abstract: Experiments on the reinfection of laboratory animals with melioidosis revealed that guinea-pigs and white mice developed pronounced resistance to the disease, accompanied by the objective [corrected] signs of immunologic transformation (allergization, the presence of specific humoral antibodies, and increase in the phagocytic activity of the cells of the macrophage system). In golden hamsters, highly sensitive to infection with Pseudomonas pseudomallei culture, the process of the "all or nothing" type occurs, and the degree of resistance depends on the fluctuations of the individual sensitivity level. No phenomena of immunologic transformation were observed in reinfected golden hamsters.
mesh_terms: D000208:Acute Disease; D000818:Animals; D006224:Cricetinae; D006168:Guinea Pigs; D007156:Immunologic Memory; D008264:Macrophages / Q000276:immunology; D008554:Melioidosis / Q000276:immunology* / Q000517:prevention & control; D051379:Mice; D008815:Mice, Inbred Strains; D011549:Pseudomonas / Q000472:pathogenicity; D013045:Species Specificity; D014611:Vaccination; D014774:Virulence
vernacular_title: Postinfektsionnyĭ immunitet pri melioidoze.