I and H activities of human red blood cells treated with an 1, 2-alpha-L-fucosidase from Aspergillus niger.
After treatment with the 1, 2-alpha-L-fucosidase of Aspergillus niger, the H antigen activity of red cells from normal H phenotypes is abolished and I activity is simultaneously increased. We suggest that this change could be related to the better accessibility to antibodies of the I erytrocyte receptors.
D000017:ABO Blood-Group System; D001234:Aspergillus niger / Q000201:enzymology*; D001789:Blood Group Antigens; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D007048:I Blood-Group System; D012463:Saliva / Q000378:metabolism; D005644:alpha-L-Fucosidase / Q000494:pharmacology*
D000017:ABO Blood-Group System; D001789:Blood Group Antigens; D007048:I Blood-Group System; D005644:alpha-L-Fucosidase