Cimetidine potentiates the anticoagulant effect of warfarin by inhibition of drug metabolism.
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D002927:Cimetidine / Q000494:pharmacology*; D004357:Drug Synergism; D006146:Guanidines / Q000494:pharmacology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D010243:Paralysis / Q000139:chemically induced; D010424:Pentobarbital / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014859:Warfarin / Q000378:metabolism / Q000494:pharmacology*; D015049:Zoxazolamine / Q000494:pharmacology
D006146:Guanidines; D014859:Warfarin; D002927:Cimetidine; D015049:Zoxazolamine; D010424:Pentobarbital