Proceedings of the Symposium on Designs for Clinical Cancer Research. Summary views: A statistician's perspective.
This paper outlines some broad issues concerning the role of statistical methods, and argues for flexibility of approach. It reviews the controversies concerning historical versus concurrent controls, and randomization versus extensive balancing. Finally, it proposes directions in which further developments of statistical technique would be desirable.
D005544:Forecasting; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D011897:Random Allocation; D012107:Research Design; D012189:Retrospective Studies; D013223:Statistics as Topic