title: [Combination therapy of delirium tremens with haloperidol and clomethiazol (author's transl)].
abstract: Despite the successes achieved by modern distraneurinomonotherapy, treatment of delirium tremens remains full of complications and high-risk problem. Basing on theoretical considerations regarding the delirium tremens as a form of psychosis, the additional application of a neuroleptic with an antipsychotic action is suggested to achieve a specific treatment, exercising a direct influence both on the psychotic and on the neurovegetative signs of alcoholic delirium. Experiences collected with a combination treatment extending over two years with haloperidol IV and ch clomethiazol oral, point to a decrease in the incidence rate of delirium, a milder course of the delirium itself, and a corresponding decrease in associated complications. This should stimulate further systematic and statistically safe investigations in this field.
mesh_terms: D000430:Alcohol Withdrawal Delirium / Q000188:drug therapy*; D002719:Chlormethiazole / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006220:Haloperidol / Q000627:therapeutic use*; D006801:Humans; D011604:Psychoses, Alcoholic / Q000188:drug therapy*
chemical_list: D002719:Chlormethiazole; D006220:Haloperidol
vernacular_title: Kombinationstherapie des Alkoholdelirs mit Haloperidol und Clomethiazol.