Metabolism of alpha- and beta-pinene, p-cymene and 1,8-cineole in the brushtail possum, Trichosurus vulpecula.
1. The nature of the non-conjugated metabolites of the Eucalyptus oil terpenoid components alpha-pinene, beta-pinene, p-cymene and 1,8-cineole in the urine and faeces of the brushtail possum was investigated. 2. alpha-Pinene was metabolized to myrtenic acid and trans-verbenol, beta-pinene to myrtenic acid, p-cymene to p-cresol and cumic acid, and 1,8-cineole to p-cresol, 9-hydroxycineole and cineol-9-oic acid.
D000818:Animals; D000081008:Bicyclic Monoterpenes; D001711:Biotransformation; D001643:Bridged Bicyclo Compounds / Q000378:metabolism*; D001952:Bridged-Ring Compounds / Q000378:metabolism*; D003511:Cyclohexanols; D000081007:Cymenes; D004852:Epoxy Compounds / Q000378:metabolism; D000077591:Eucalyptol; D005052:Eucalyptus; D005243:Feces / Q000032:analysis; D005260:Female; D007536:Isomerism; D008297:Male; D008610:Menthol / Q000031:analogs & derivatives* / Q000378:metabolism; D039821:Monoterpenes; D009893:Opossums / Q000378:metabolism*; D010946:Plants, Medicinal; D013729:Terpenes / Q000378:metabolism*
D000081008:Bicyclic Monoterpenes; D001643:Bridged Bicyclo Compounds; D001952:Bridged-Ring Compounds; D003511:Cyclohexanols; D000081007:Cymenes; D004852:Epoxy Compounds; D039821:Monoterpenes; D013729:Terpenes; D008610:Menthol; C007210:4-cymene; C010789:beta-pinene; C005451:alpha-pinene; D000077591:Eucalyptol