title: [Effect of antibiotics on spontaneous and direct migration of human leukocytes. Preliminary findings].
abstract: Like other human blood cells, neutrophiles can travel enter tissues spontaneously. This apparently casual journeying is arrested in the presence of infection and they migrate to the site of the lesion. Experiments in vitro have shown that tetracycline, rifamycin, chloramphenicol, and cefuroxine inhibit such migration. In the present paper, it is demonstrated that ampicillin and tauglycolcillin, a new semi-synthetic penicillin, exert no significant influence on either direct or spontaneous neutrophile migration.
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002465:Cell Movement / Q000187:drug effects*; D006098:Granulocytes / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007239:Infections / Q000188:drug therapy / Q000276:immunology*; D009504:Neutrophils / Q000187:drug effects; D011928:Raynaud Disease / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Effetto degli antibiotici sulla migrazione spontanea e diretta dei leucociti umani. Risultati preliminari.