Chemotaxigenesis by encapsulated Staphylococcus aureus M.
Although encapsulated Staphylococcus aureus M is not opsonized by normal human serum, as a chemotaxigen this organism behaved similarly to an unencapsulated variant strain. For optimal chemotaxigenesis, an intact classical complement pathway was required, and C5a appeared to be the major chemotaxin.
D002630:Chemotactic Factors / Q000502:physiology; D002634:Chemotaxis, Leukocyte; D003182:Complement C5 / Q000502:physiology; D003171:Complement Pathway, Classical; D009504:Neutrophils; D013211:Staphylococcus aureus / Q000166:cytology / Q000502:physiology*; D013499:Surface Properties
D002630:Chemotactic Factors; D003182:Complement C5