title: Effect of disinfectants on pathogenic free-living amoebae: in axenic conditions.
abstract: The amoebicidal properties of chlorine, chlorine dioxide, ozone, and deciquam 222 were examined in axenic conditions. Naegleria spp. were found to be more sensitive to chlorine and chlorine dioxide than Acanthamoeba spp. No marked difference in sensitivity to ozone or deciquam 222 could be detected between the pathogenic (A-1) and nonpathogenic (1501) strains of Acanthamoeba and the pathogenic (MsT) and nonpathogenic (P1200f) strains of Naegleria. Methods of disinfection are discussed with reference to suitability of the disinfectants to real conditions.
mesh_terms: D000473:Alkanes / Q000494:pharmacology*; D000656:Amoeba / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity; D000818:Animals; D002713:Chlorine / Q000494:pharmacology*; D017606:Chlorine Compounds; D004202:Disinfectants; D010087:Oxides / Q000494:pharmacology*; D010126:Ozone / Q000494:pharmacology*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D000473:Alkanes; D017606:Chlorine Compounds; D004202:Disinfectants; D010087:Oxides; D000644:Quaternary Ammonium Compounds; D002713:Chlorine; D010126:Ozone; C025109:chlorine dioxide; C027118:didecyldimethylammonium