Induction of intranuclear microtubules in chick embryo fibroblasts by frog virus 3.
Intranuclear microtubules appear in chick embryo fibroblasts upon infection with Frog Virus 3 (FV 3). Both the diameter and the annular shape of the microtubule profiles, established from electron microscopic observations using a goniometer, suggest that they are identical to naturally occurring cytoplasmic microtubules. Furthermore, the use of vinblastine allowed demonstration of the tubulin composition of the intranuclear microtubules.
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D002478:Cells, Cultured; D002642:Chick Embryo; D003593:Cytoplasm / Q000648:ultrastructure; D005347:Fibroblasts; D007497:Iridoviridae / Q000254:growth & development*; D008870:Microtubules / Q000032:analysis / Q000648:ultrastructure*; D014404:Tubulin / Q000032:analysis
D014404:Tubulin