[Pattern of steroid hormones in patients with acute leukemia].
The cortisol metabolism was studied in patients with different variants of acute leukemia. In total amount of C21-steroid excreted with urine the portion of cortisol was decreased, the increased cortisol conversion into 20-dihydrometabolites and the decreased cortisol portion, conversed through the stage of cortisone into tetrahydrocortisone, were observed. Also, disturbances in steroid conjugation with glucuronic and sulfuric acids and the increased progesterone concentration in peripheral blood plasma were noted.
D000208:Acute Disease; D001711:Biotransformation; D005965:Glucuronates / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D007938:Leukemia / Q000378:metabolism*; D013464:Sulfuric Acids / Q000378:metabolism
D005965:Glucuronates; D013464:Sulfuric Acids; D006854:Hydrocortisone
Osobennosti obmena steroidnykh gormonov u bol'nykh ostrymi leĭkozami.