title: Cryosurgical treatment of cervical intraepithelial neoplasia.
abstract: This report describes 354 patients treated with cryosurgery for cervical intraepithelial neoplasia (CIN) over an 8-year period. Colposcopic criteria were used to select treatable patients and to perform colposcopically directed biopsies. Treatment failures occurred in 6.2% of 298 patients treated for CIN I and II lesions. Of patients treated for carcinoma in situ, 39% demonstrated persistence of this lesion. Based on this clinical experience, cryosurgery is no longer acceptable for the treatment of severe dysplasia or cervical carcinoma in situ.
mesh_terms: D002278:Carcinoma in Situ / Q000601:surgery*; D003452:Cryosurgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000601:surgery*