Relationship between hepatic metabolism of chlorpromazine and cholestatic effects in the isolated perfused rat liver.
D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D001711:Biotransformation; D002746:Chlorpromazine / Q000378:metabolism* / Q000494:pharmacology; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced*; D004790:Enzyme Induction / Q000187:drug effects; D006900:Hydroxylation; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D010477:Perfusion; D051381:Rats; D013454:Sulfoxides / Q000378:metabolism
D001647:Bile Acids and Salts; D013454:Sulfoxides; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D002746:Chlorpromazine