Lymphomatoid papulosis. Ultrastructural study with demonstration of intranuclear and intracytoplasmic viruslike particles.
Transmission electron microscopic study of the bizarre infiltrating cells from a case of lymphomatoid papulosis reveals intranuclear and intracytoplasmic virus-like particles. These cells have large nuclei with multiple nucleoli, scant to moderate profiles of rough endoplasmic reticulum, mitochondria and a variable number of lysosomes. It is suggested that these abnormal cells are macrophages showing viral cytopathogenic effects.
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure; D003588:Cytopathogenic Effect, Viral; D003593:Cytoplasm / Q000648:ultrastructure; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008264:Macrophages / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000382:microbiology / Q000648:ultrastructure; D012871:Skin Diseases / Q000382:microbiology* / Q000473:pathology