title: [Use of an oxytetracycline nasal spray in the treatment and prevention of atrophic rhinitis in piglets (author's transl)].
abstract: The piglets of two multiplier herds (M and B) showing clinically apparent atrophic rhinitis (AR) were treated by the nasal-spray method. A solution of oxytetracycline hydrochloride (OTC, 50 mg/ml.) was used as a spray fluid. The course of the disease in the herds was followed by studying the development of foreshortening of the upper jaws in the heads. Brachygnathia superior (BS), from the eighth to tenth week of life. Efforts were made to gain an impression of the effects of treatment on the frequency with which Bordetella bronchiseptica and Pasteurella multocida were isolated by bacteriological examination of the nose. Treatment by the nasal-spray method up to an age of approximately five weeks, of seven weeks were treated at least once weekly. The proportion of animals in which the disease was clinically apparent decreased from 25 per cent to 0 per cent in herd M and from 41 per cent to 0 per cent in herd B. Treatment by the nasal-spray method up to an age approximately five weeks, in which feed medicated with OTC was also given up to the age of eight to ten weeks also had a satisfactory effect. The frequency with which Bordetella bronchiseptica and Pasteurella multocida were isolated, was reduced by treatment, elimination of these agents was not.
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D001884:Bordetella / Q000302:isolation & purification; D009666:Nose / Q000382:microbiology; D010118:Oxytetracycline / Q000008:administration & dosage*; D010325:Pasteurella / Q000302:isolation & purification; D012222:Rhinitis, Atrophic / Q000517:prevention & control / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*
chemical_list: D010118:Oxytetracycline
vernacular_title: Het gebruik van oxytetracycline-HCl neusspray bij biggen ter bestrijding en preventie van atrofische rhinitis.