Ca2+-induced isotropic motion and phosphatidylcholine flip-flop in phosphatidylcholine-cardiolipin bilayers.
Ca2+ induces a structural change in phosphatidylcholine-cardiolipin bilayers, which is visualised by freeze-fracturing as lipidic particles associated with the bilayer and is detected by 31P-NMR as isotropic motion of the phospholipids. In this structure a rapid transbilayer movement of phosphatidylcholine and a highly increased permeability towards Mn2+ are observed.
D002118:Calcium; D002308:Cardiolipins; D005614:Freeze Fracturing; D007700:Kinetics; D008051:Lipid Bilayers; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese; D008968:Molecular Conformation; D010713:Phosphatidylcholines
D002308:Cardiolipins; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D008345:Manganese; D002118:Calcium