[The value of cell proliferation and histomorphology in the planned treatment of laryngeal neoplasms].
The separation of phases in cell division and the recognition gained in tissue population kinetics have contributed to enhance our knowledge of the biological behaviour of the tumours. Besides the determination of clinical characteristics (localization, TNM state) and the onchotype of a given tumour, findings obtained by cell-kinetic parameters seem to be of great importance. Relations between the degree of malignity and the data obtained by autoradiography were studied in patients suffering from laryngeal cancer. On the basis of the simple clinical determination of L.I. and Ts, estimation of further cell-kinetic parameters in a given tumour has become possible and the number of cells in the same cycle, the growth faction, and the potential doubling-time can be deduced. After the radiographic investigation of 78 cases of laryngeal tumour a relation was found between the extent of the labelling index and the biological behaviour of the tumour.
D002455:Cell Division; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D006801:Humans; D007553:Isotope Labeling; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D010347:Patient Care Planning; D011379:Prognosis
D004273:DNA, Neoplasm
Die Bedeutung der Zellproliferation und Histomorphologie bei der Geplanten Behandlung der Kehlkopfkarzinome.