title: [Aetiological treatment of benign goitre with l-thyroxine (author's transl)].
abstract: L-Thyroxine was given to 3956 patients with benign goitre between 1974 and 1977, 2314 of which were controlled over a period of 3 years at regular intervals. Benign goitre in children less than 14 years old and postoperative recurrences were not evaluated. Definite reduction in goitre size wss achieved in 77.2% of patients by continuous long-term treatment over 3 years. In large goitres and those with nodular transformation the status quo was maintained in all but exceptional cases.
mesh_terms: D005260:Female; D006042:Goiter / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D008297:Male; D012008:Recurrence; D013974:Thyroxine / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D013974:Thyroxine
vernacular_title: Die kausale Therapie der primär-blanden Struma mit L-Thyroxin.