Leucogenenol a thymothyroid hormone.
Thymectomy and, to a lesser extent, thyroidectomy cause a significant decrease in the serum leucogenenol levels of rats. Daily injections of neonatally thymectomized mice with leucogenenol causes the mice to maintain a normal level of neutrophils and lymphocytes in their circulation. The thymus and thyroid are the only tissues in rats and mice that afford radioactive leucogenenol when incubated in a medium containing radioactive D-glucose. It is concluded that the thymus and possibly the thyroid are responsible for the normal biosynthesis of leucogenenol in animals.
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D005260:Female; D007932:Leucogenenol / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000378:metabolism; D010053:Ovary / Q000378:metabolism; D010902:Pituitary Gland / Q000378:metabolism; D051381:Rats; D013045:Species Specificity; D013141:Spiro Compounds / Q000096:biosynthesis*; D013154:Spleen / Q000378:metabolism; D013737:Testis / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism*
D013141:Spiro Compounds; D007932:Leucogenenol