title: Ontogeny of the pineal melatonin rhythm in the Syrian (Mesocricetus auratus) and Siberian (Phodopus sungorus) hamsters and in the rat.
abstract: The ontogeny of the pineal melatonin rhythm was determined in three rodent species. Pineal glands were obtained either during the day or during the expected peak in melatonin at night. In all species the rhythm was first detected during the second week of life. Investigations of the photic regulation of pineal melatonin revealed that light could inhibit the nocturnal increase in melatonin in all species by the end of the second week of life. These studies indicate that for these species the development of the rhythm in pineal melatonin and the development of the mechanism involved in the photic suppression of the nocturnal increase in melatonin are independent of the role the pineal gland plays in regulating reproductive function in response to changes in environmental lighting.
mesh_terms: D000375:Aging; D000818:Animals; D002940:Circadian Rhythm; D006224:Cricetinae; D005260:Female; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D008647:Mesocricetus; D010870:Pineal Gland / Q000254:growth & development* / Q000378:metabolism; D051381:Rats; D013045:Species Specificity
chemical_list: D008550:Melatonin