[Assay of 3-methoxy 4-hydroxyphenyl ethylene glycol (MHPG) and its conjugates in the urine (author's transl)].
Urinary MHPG was assayed by gas chromatography using a flame ionisation detector. The technic proposed was reproducible, repeatable and linear. The frequent values determined in adult subjects of both sexes were 8.64 1.34 mumol/24 h without any difference between the sexes. On the other hand, urinary excretion of total MHPG showed a positive correlation with age. It was excreted in the conjugated form, of which 50 p. cent was sulphoconjugated, 41 p. cent glucuroconjugated, and 9 p. cent free. Owing to its simplicity, this method may be applied to the study of mood disorders.
D000328:Adult; D000375:Aging; D005260:Female; D005410:Flame Ionization / Q000379:methods; D006018:Glycols / Q000652:urine*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D008875:Middle Aged
D006018:Glycols; D008734:Methoxyhydroxyphenylglycol
Dosage du 3-méthoxy 4-hydroxyphényléthylène glycol (MHPG) et de ses conjugués dans l'urine.