title: Growth rate of giant-cell tumor of bone: radiographic and clinical considerations.
abstract: The progression of giant-cell tumor of bone was studied in 2 patients, a 16-year-old girl and a 26-year-old man with abnormalities of the cancellous bone in the distal femur. The tumors had been overlooked in the first roentgenographic examination, and the patients were discharged without treatment. In the girl, the tumor grew from 33 cm3 to 85 cm3 in 65 days, and in the man from 11 cm3 to 175 cm3 in 311 days before the lesions were diagnosed. The high rate of growth of these neoplasms reflects the inherent malignancy of giant-cell tumors around the knee.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005870:Giant Cell Tumors / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006128:Growth; D006801:Humans; D008297:Male; D011859:Radiography