title: Multidose studies in the human metabolism of pentobarbitone.
abstract: The metabolism of pentobarbitone has been investigated in two healthy volunteers, and the urinary excretion of unchanged drug, and the products of omega- and (omega-1)-oxidation, quantified for four days after each of three doses to each volunteer. The rates of excretion are discussed in terms which include enzyme induction effects.
mesh_terms: D001711:Biotransformation; D006801:Humans; D006900:Hydroxylation; D007700:Kinetics; D008297:Male; D010084:Oxidation-Reduction; D010424:Pentobarbital / Q000008:administration & dosage / Q000378:metabolism* / Q000652:urine
chemical_list: D010424:Pentobarbital