title: Maximal expiratory flow volume curves in workers exposed to asbestos.
abstract: We have studied 40 workers with varying industrial exposure to asbestos, using routine spirometry and maximal expiratory flow volume curves (MEFVC). Abnormalities of MEFVC were common and seen in those with normal spirometry and total lung capacity. The high incidence of abnormal MEFVC suggests that air flow dysfunction in small airways may follow prolonged asbestos exposure. Our findings support, therefore, the idea that asbestos exposure may cause an obstruction to airflow arising particularly in small airways, and that one of the common functional abnormalities attributable to asbestos exposure is airways obstruction.
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000209:etiology* / Q000503:physiopathology; D001194:Asbestos / Q000494:pharmacology*; D001195:Asbestosis / Q000503:physiopathology*; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008449:Maximal Expiratory Flow-Volume Curves; D008875:Middle Aged; D012123:Pulmonary Ventilation / Q000187:drug effects*; D012907:Smoking / Q000150:complications; D013147:Spirometry
chemical_list: D001194:Asbestos