Chromosome studies in mycosis fungoides.
G-banded chromosome analysis was performed on peripheral blood lymphocytes after phytohaemagglutinin stimulation from sixteen patients with mycosis fungoides. A number of chromosome abnormalities were observed in a low proportion of blood lymphocytes in seven patients in later stages of the disease. In four patients similar marker chromosomes in multiple copies were present, some of them without a clearly visible centromere. We conclude that a correlation exists between the presence of chromosome abnormalities in circulating blood lymphocytes and the course of the disease.
D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000235:genetics* / Q000473:pathology; D010835:Phytohemagglutinins / Q000494:pharmacology; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology
D010835:Phytohemagglutinins