title: The pathophysiology of arthrogryposis multiplex congenita neurologica.
abstract: Eleven patients with arthrogryposis multiplex congenita neurologica have been reviewed. Distinct patterns of deformity and muscle activity were identified which have been correlated with specific levels of segmental neurological motor deficit without sensory loss. The clinical picture was consistent with localised lesions of the anterior horn cell cell columns. This finding agreed with the recorded pathological lesions. Orthopaedic treatment should take account of the paralytic nature of the deformities.
mesh_terms: D000293:Adolescent; D000328:Adult; D000870:Anterior Horn Cells / Q000473:pathology; D001176:Arthrogryposis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009132:Muscles / Q000294:innervation; D010243:Paralysis / Q000150:complications / Q000473:pathology*; D013118:Spinal Cord Diseases / Q000150:complications / Q000473:pathology*; D013577:Syndrome