Synthesis of 1,3-diazepin-2-one nucleosides as transition-state inhibitors of cytidine deaminase.
D000818:Animals; D001381:Azepines / Q000138:chemical synthesis* / Q000494:pharmacology; D003564:Cytidine Deaminase / Q000037:antagonists & inhibitors*; D006801:Humans; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D051379:Mice; D008968:Molecular Conformation; D009700:Nucleoside Deaminases / Q000037:antagonists & inhibitors*; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D001381:Azepines; D009705:Nucleosides; D009700:Nucleoside Deaminases; D003564:Cytidine Deaminase