Lack of cardiovascular stimulation during endotracheal intubation in cardiac surgical patients anesthetized with diazepam-ketamine-pancuronium.
Anesthesia was induced with diazepam-ketamine-pancuronium in 12 adult patients scheduled for cardiac surgery. Intubation caused no significant changes in arterial blood pressure, heart rate, or plasma levels of norepinephrine and epinephrine. Circulatory stability was an advantage in critically ill patients.
D000328:Adult; D000368:Aged; D000758:Anesthesia; D001794:Blood Pressure / Q000187:drug effects; D006348:Cardiac Surgical Procedures; D002319:Cardiovascular System / Q000187:drug effects*; D003975:Diazepam / Q000008:administration & dosage / Q000494:pharmacology*; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007442:Intubation, Intratracheal; D007649:Ketamine / Q000008:administration & dosage / Q000494:pharmacology*; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D010197:Pancuronium / Q000008:administration & dosage / Q000494:pharmacology*
D007649:Ketamine; D010197:Pancuronium; D003975:Diazepam; D009638:Norepinephrine