title: [Possibility of protecting vertebrates against transmissive infection with tick-borne encephalitis virus].
abstract: A previously unknown phenomenon of reproduction inhibition and limitation of dissemination of virus agents transmitted by ticks to mammals by the effect of the immunity of vertebrates directed against blood-sucking arthropods was established. Inoculation of the animals with serum immune to uninfected tick saliva antigens led to inhibition of tick-borne encephalitis virus reproduction in them by 1.75--3.0 lg LD50/0.03 ml when the animals had been infected transmissively (by feeding of infected ticks on them). On the animals containing antibody to tick saliva antigens no virus transmission from infected ticks to non-infected vectors occurred upon their simultaneous parasitizing.
mesh_terms: D000818:Animals; D004669:Encephalitis Viruses, Tick-Borne / Q000254:growth & development / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000517:prevention & control* / Q000635:transmission; D007116:Immunization, Passive; D051379:Mice; D011817:Rabbits; D012463:Saliva / Q000276:immunology; D013987:Ticks / Q000276:immunology
vernacular_title: Izuchenie vozmozhnosti predokhraneniia pozvonochnykh zhivotnykh ot transmissivnogo zaracheniia virusom kleschevogo éntsefalita.