The use of stereoisomers in patch testing.
A patient is described with a clinical picture resembling that of relapsing scarlatina. The complaints were found to be based on two types of delayed-type allergy: one to the equatorially bound hydroxyl grouip at the 6 position of the basic phenanthrene structure as occurs in morphine and codeine, and the other to the D(-)-alpha-position of the amino group as occurs in some penicillin derivatives.
D000293:Adolescent; D004342:Drug Hypersensitivity / Q000175:diagnosis*; D005260:Female; D006801:Humans; D010406:Penicillins / Q000009:adverse effects; D010616:Phenanthrenes / Q000009:adverse effects; D012541:Scarlet Fever / Q000175:diagnosis*; D012882:Skin Tests; D013237:Stereoisomerism
D010406:Penicillins; D010616:Phenanthrenes