Chemotherapeutic management of transmissible venereal tumors in 30 dogs.
Thirty dogs with transmissible venereal tumors were examined either at The Donaldson-Atwood Cancer Clinic of The Animal Medical Center or at The University of Georgia Veterinary Medical Teaching Hospital. After biopsy, all dogs were treated with a combination chemotherapy regimen consisting of vincristine, cyclophosphamide, and methotrexate. Results of therapy were evaluated after a mean interval of 533 days; 28 had complete regression of tumor, 1 had a partial response, and 1 had a minimal response.
D000818:Animals; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004359:Drug Therapy, Combination; D005260:Female; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use; D014685:Venereal Tumors, Veterinary / Q000188:drug therapy*; D014750:Vincristine / Q000008:administration & dosage / Q000627:therapeutic use
D014750:Vincristine; D003520:Cyclophosphamide; D008727:Methotrexate