title: [Studies on the relationship between 2-iminothiazolidine-4-carboxylic acid and the thiocyanate metabolism in the guinea-pig (author's transl)].
abstract: In vitro and in vivo experiments have been carried out to elucidate the metabolism of 2-iminothiazolidine-4-carboxylic acid (ITC). By using 35S-ITC, the formation of 35SCN as well as of 35S-containing ITC metabolites could be excluded. As compared to the findings from control animals, the serum thiocyanate levels determined in guinea-pigs after oral administration of ITC were unchanged.
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D051381:Rats; D013462:Sulfur Radioisotopes; D013844:Thiazoles / Q000378:metabolism*; D013861:Thiocyanates / Q000097:blood / Q000378:metabolism*
chemical_list: D013462:Sulfur Radioisotopes; D013844:Thiazoles; D013861:Thiocyanates; C015674:2-amino-delta(2)-thiazoline-4-carboxylic acid
vernacular_title: Untersuchungen zur Beziehung zwischen der 2-Iminothiazolidin-4-carbonsäure und dem Thiocyanatstoffwechsel des Meerschweinchens.