A simple method for determining whether absorption and elimination rate constants are equal in the one-compartment open model with first-order processes.
A simple method is presented by which one may determine if the absorption and the elimination rate constants are equal (in the one-compartment body model) using only plasma drug data. This method suggests the pertinent equation to calculate the relevent pharmacokinetic parameters.
D007408:Intestinal Absorption; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*
D004364:Pharmaceutical Preparations