title: [Eye and hair pigmentation in malignant melanomas and other malignant skin tumors].
abstract: With the intent to determine whether the phenotypic appearance of individuals with skin malignancies could be differentiated from individuals without such tumors, an objective standardized analysis of 183 patients with malignant melanoma and 111 patients with basal cell epithelioma, squamous cell epithelioma and premalignant skin lesions was undertaken. Eye color and hair color were studied in addition to birthplace of the patients. 527 patients without history of tumors were utilized as controls. High risk persons are characterized by light iris colors (for the melanoma group significance of 0.05%, for other tumors significance of 0.001%) and blond or reddish blond hair (for the melanoma group significance of 0.001%). The melanoma patients originated to a greater part from regions north from their present residence (significance of 0.01%) than the group of non-melanoma patients, who originated more often from the vicinity of Maniz (50 degrees N latitude).
mesh_terms: D000368:Aged; D005127:Eye Color; D005260:Female; D005860:Germany, West; D006200:Hair Color; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology* / Q000503:physiopathology; D008875:Middle Aged; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000503:physiopathology
vernacular_title: Augen- und Haarpigmentierung beim malignen Melanom und anderen malignen Hauttumoren.