title: Multivariate analysis of the effects of manganese on the reproductive physiology and behavior of the male house mouse.
abstract: Chronic exposure to Mn3O4 in the diet at 1050 ppm Mn retarded the sexual development and lowered reactive locomotor activity levels in male mice. A multivariate analysis of variance indicated that testis, seminal vesicle, and preputial gland weights were significantly smaller as a result of Mn administration. These results support earlier observations of altered locomotor activity levels and reproductive development in male rats in the absence of other signs of toxicity.
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D008297:Male; D008345:Manganese / Q000494:pharmacology*; D051379:Mice; D012098:Reproduction / Q000187:drug effects*; D012669:Seminal Vesicles / Q000187:drug effects; D013737:Testis / Q000187:drug effects
chemical_list: D008345:Manganese