Ultrasonic irradiation of mammalian cells in vitro at hyperthermic temperatures.
Suspensions of V79 cells and HeLa cells have been irradiated with continuous 3 MHz ultrasound at a spatial average intensity of 3W cm-2. This irradiation condition did not give rise to cell lysis. When the cells were irradiated with ultrasound for up to six hours at 37 degrees C no cell killing was observed. However, at temperatures in the hyperthermia range 42--45 degrees C the increase in cell killing that resulted from the irradiation was greater than that which could be attributed to its heating effect alone.
D000818:Animals; D002460:Cell Line; D002470:Cell Survival; D006224:Cricetinae; D003412:Cricetulus; D005347:Fibroblasts / Q000166:cytology; D006367:HeLa Cells / Q000166:cytology; D006358:Hot Temperature; D006801:Humans; D008168:Lung / Q000166:cytology; D014465:Ultrasonics