Intracranial disease in non-Hodgkin's lymphoma.
In an eighteen month period ending October 1978, nine cases of intracranial Non-Hodgkin's lymphoma were diagnosed in this centre. Eight patients had lymphomatous meningitis and one, multiple intracerebral lymphoma deposits. The commonest presentation was with multiple cranial nerve palsies. Despite treatment five patients died within one month of diagnosis and at autopsy three patients were found to have extensive lymphoma involving the meninges. Three patients remain in remission after combination chemotherapy and radiotherapy. The incidence, clinical features, management and prognosis for this condition are discussed.
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000628:therapy; D002555:Cerebrospinal Fluid / Q000166:cytology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D005260:Female; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes; D008223:Lymphoma / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000134:cerebrospinal fluid; D011379:Prognosis; D014057:Tomography, X-Ray Computed
D002556:Cerebrospinal Fluid Proteins; D009113:Muramidase; D005947:Glucose