title: [Effect of cimetidine and synthetic secretin as treatment of acute upper gastrointestinal bleeding--a prospective alternate trial (author's transl)].
abstract: The effect of cimetidine respectively synthetic secretin was investigated in a prospective alternate trial on 20 patients with an acute non arterial bleeding from acute ulcers respectively hemorrhagic erosions of the stomach or duodenal bulb. 48 hours after beginning therapy the bleeding stopped in 3 patients treated with cimetidine and in 9 treated with secretin. During this time 2 patients of both groups rebled. The trial showed that secretin was superior to cimetidine (chi 2-test, p  < 0.01).
mesh_terms: D002927:Cimetidine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D010438:Peptic Ulcer Hemorrhage / Q000188:drug therapy*; D011446:Prospective Studies; D012633:Secretin / Q000627:therapeutic use*
chemical_list: D006146:Guanidines; D012633:Secretin; D002927:Cimetidine
vernacular_title: Effekt von Cimetidin und Sekretin bei akuten Blutungen aus Magen und Duodenum--Ergebnisse einer prospektiven alternierenden Studie.