[Hepatic and renal toxicity of enflurane (author's transl)].
Enflurane has been implicated with both hepatic and renal toxicity. Others factors associated with similar dysfunction in the post operative period should be ruled out before the drug can be incriminated. We are reporting a case of mild post operative jaundice and transient renal insufficiency associated with enflurane anesthesia, which was eventually treated vigorously and successfully. The exact frequency of this kind of post operative complication is still unknown. Although other types of viral hepatitis cannot be completely ruled out, the anesthesiologist should be aware of the potential hazard of hepatic and renal toxicity attributed to enflurane. He should also be prepared to initiate vigorous treatment of the syndrome as soon as it appears so as to increase the chance for a successful outcome.
D000328:Adult; D000758:Anesthesia; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004737:Enflurane / Q000009:adverse effects*; D006801:Humans; D007565:Jaundice / Q000139:chemically induced; D007674:Kidney Diseases / Q000139:chemically induced*; D008297:Male
D004737:Enflurane
Atteinte hépato-rénale après anesthésie à l'enflurane.