Hyperkalaemic paralysis, neuropathy and persistent motor neuron discharges at rest in Addison's disease.
A 50 year old man with Addison's disease suffered two episodes of hyperkalaemic paralysis, with delayed muscular relaxation and persistent motor neuron discharges at rest resembling the Isaacs-Mertens syndrome. Sural nerve biopsy shows a demyelinating neuropathy. The symptoms ceased after corticosteroid therapy.
D000224:Addison Disease / Q000175:diagnosis*; D003711:Demyelinating Diseases / Q000175:diagnosis; D006801:Humans; D006947:Hyperkalemia / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009468:Neuromuscular Diseases / Q000175:diagnosis*; D013577:Syndrome