title: Occurrence of seizure during cranial computed tomography.
abstract: With the advent of cranial computed tomography, the incidence of contrast-induced convulsion has increased. The reason for this is threefold: (a) Contrast media after the permeability of the blood-brain barrier, enabling toxins, drugs, and perhaps the contrast agent itself to enter the brain; (b) the vessels of neoplasms and their surrounding tissue are already more permeable, enabling contrast medium to leak from these vessels into the brain; (c) since patients coming to contrast-enhanced cranial CT have a relatively high incidence of neoplastic lesions of the brain, they are therefore at greater risk for convulsive episodes.
mesh_terms: D000792:Angiography; D001812:Blood-Brain Barrier / Q000187:drug effects; D001932:Brain Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D002199:Capillary Permeability / Q000187:drug effects; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D012640:Seizures / Q000139:chemically induced*; D012886:Skull / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000009:adverse effects*; D014567:Urography
chemical_list: D003287:Contrast Media