title: [Disseminated histoplasmosis in children].
abstract: Clinical features and treatment evaluation of 38 children with disseminated histoplasmosis were studied. Thirty-six cases presented the severe form and two of them showed the mild chronic type. A higher incidence of this disease was found in infants (65%) and in severe malnutrition (68%) and lethality in the overall group was 61%. Patients died either because they did not receive specific treatment or were given amphotericin for less than 15 days. These figures stress the importance of this treatment in disseminated histoplasmosis.
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007275:Injections, Intravenous; D014295:Trimethoprim / Q000627:therapeutic use
chemical_list: D000666:Amphotericin B; D014295:Trimethoprim
vernacular_title: Histoplasmosis diseminada en niños.