The influence of D-glucose of phosphate absorption in the rat proximal tubule.
The present studies demonstrate that a tubular maximum for phosphate absorption is present in the proximal tubule in the rat. In addition, the presence of D-glucose in the solution on the luminal side of the renal tubular cells inhibits phosphate absorption. The effect of D-glucose on phosphate absorption requires the tubular absorption of D-glucose and does not appear to be due to an interaction between glucose and phosphate at the luminal surface of the renal tubular cells.
D000042:Absorption; D000818:Animals; D005947:Glucose / Q000494:pharmacology*; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D008297:Male; D010695:Phlorhizin / Q000494:pharmacology; D010710:Phosphates / Q000378:metabolism*; D051381:Rats
D010710:Phosphates; D010695:Phlorhizin; D005947:Glucose