[Granulocytopenia with cimetidine therapy (author's transl)].
In a 38-year-old patient with alcoholic liver cirrhosis and haemorrhage from a gastric ulcer, granulocytopenia occurred during cimetidine treatment. It was reversible after therapy was stopped. The platelet count also fell during cimetidine and a reduction of megakaryocytes was found in the bone marrow.
D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced* / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002927:Cimetidine / Q000009:adverse effects* / Q000627:therapeutic use; D006146:Guanidines / Q000009:adverse effects*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D008533:Megakaryocytes; D010438:Peptic Ulcer Hemorrhage / Q000150:complications / Q000188:drug therapy; D010976:Platelet Count
D006146:Guanidines; D002927:Cimetidine
Granulozytopenie unter Cimetidintherapie.