Blood pressure responses of rats to angiotensin I and II after exposure to cigarette smoke.
One day after a single exposure of rats to cigarette smoke their blood pressure responses to intravenous injections of angiotensin I and II were slightly increased in comparison to sham-exposed animals. When the exposure was repeated daily during ten consecutive days, no changes could be detected. These results suggest, that the total conversion of angiotensin I in vivo was not affected by cigarette smoke but the sensitivity of rats to angiotensin II was slightly increased after a single exposure to cigarette smoke.
D000803:Angiotensin I / Q000494:pharmacology*; D000804:Angiotensin II / Q000494:pharmacology*; D000809:Angiotensins / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D008297:Male; D010100:Oxygen / Q000097:blood; D051381:Rats; D012907:Smoking
D000809:Angiotensins; D000804:Angiotensin II; D000803:Angiotensin I; D010100:Oxygen