High HPRT activity in fibroblasts from patients with Lesch-Nyhan syndrome due to bacterial "L-form" contamination.
D001375:Azaguanine / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D005347:Fibroblasts / Q000201:enzymology*; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000378:metabolism*; D007042:Hypoxanthines / Q000378:metabolism; D007118:Immunoassay; D007700:Kinetics; D007740:L Forms / Q000201:enzymology*; D007926:Lesch-Nyhan Syndrome / Q000201:enzymology*; D009154:Mutation
D007042:Hypoxanthines; D007041:Hypoxanthine Phosphoribosyltransferase; D001375:Azaguanine