Estrogen receptors in male breast cancer.
Estrogen receptor assays were performed on tumor specimens from 6 male patients with documented breast cancer. Five out of six (83%) males had positive ER assays with values ranging from 23-384 femtomoles per mg cytosol protein. A review of the literature showed that 32 out of 38 patients (84%) reported were positive for estrogen receptor. Four out of five ER positive males responded to orchiectomy. Estrogen receptors are present in a high percentage of males with breast cancer and may predict response to treatment, similar to female breast cancer.
D000230:Adenocarcinoma / Q000032:analysis* / Q000175:diagnosis / Q000556:secondary; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000032:analysis* / Q000175:diagnosis / Q000556:secondary; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis*
D011960:Receptors, Estrogen