Action of thymic polypeptides of low molecular weight on some immune reactions at tissular and humoral level in guinea-pigs and mice.
Administration of the TP2 extract containing thymic polypeptides of low molecular weight (under 10,000 daltons) was found to stimulate the delayed hypersensitivity reaction in guinea-pigs injected with BCG. It was also found to reduce the hemagglutination titre in mice injected with the APR 8 influenza virus and to raise the antiflagellar agglutinins titre in rats injected with TH Salmonella vaccine. The cellular type of immune reactions was stronger than the humoral one.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001500:BCG Vaccine; D001428:Bacterial Vaccines; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular / Q000187:drug effects; D007252:Influenza Vaccines; D051379:Mice; D010455:Peptides / Q000494:pharmacology*; D012475:Salmonella; D013950:Thymus Gland
D001500:BCG Vaccine; D001428:Bacterial Vaccines; D007252:Influenza Vaccines; D010455:Peptides