Pathogenesis of jaundice in histiocytic medullary reticulosis. A correlative scintigraphic, histologic and biochemical study.
Liver scanning with 131Iodine Rose bengal was performed on two patients with histiocytic medullary reticulosis. The diagnosis was confirmed in both cases on subsequent autopsies. The studies demonstrated obstructive pattern in both cases on scanning and correlated well with the biochemical and histological findings. The pathogenesis of jaundice in this condition is reviewed and it is suggested that intrahepatic obstruction plays a significant role in its causation.
D000368:Aged; D002779:Cholestasis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008206:Lymphatic Diseases / Q000150:complications*; D008297:Male; D011877:Radionuclide Imaging