title: [Effectiveness and side-effects of intracervical application of prostaglandin F2-alpha-gel in the early weeks of pregnancy (author's transl)].
abstract: In the Womens Hospital Peine from July 1, 1976 to December 31, 1979 503 artificial abortions were carried out by intracervical application of 3 mg PGF2-Alpha-Gel. In 82.5% of the cases patients had a spontaneous abortion or a cervical dilatation. Gastrointestinal side-effects were observed in 10.5% of the cases. 27.6% of the patients complained of acute pain. Complications due to the following mechanical dilatation did not occur. In three cases patients went into a state of shock after the gel-application. This, however, was quickly reversible. A systemic reaction  an occur when PGF2-Gel is applied locally.
mesh_terms: D000028:Abortion, Induced; D000287:Administration, Topical; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012772:Shock, Septic
chemical_list: D011461:Prostaglandins F, Synthetic
vernacular_title: Wirksamkeit und Nebenwirkungen der intrazervikalen Prostaglandin F2-Alpha-Gel-Applikation im 1. Trimenon.