title: [Results of oral application of Salmonella dublin live vaccine to calves].
abstract: Orally administered streptomycin-dependent (smd) Salmonella (S.) dublin live vaccine usually is extremely well tolerated by calf under practice conditions, although other stresses may develop with high intensity (coli infection, pneumonia, S. dublin wild strain infection). Effective oral immunisation against salmonellosis of calf has proved possible in practice, but action clearly depended on dosage, as it did in clinical testing. The formula for effective oral immunisation via drinking milk is 5 . 10(10) to 1 . 10(11) smd germs daily over ten consecutive days. Satisfactory effectiveness of the oral vaccine was established by decline in clinical salmonellosis cases as well as in salmonella-caused calf loss and by bacteriological tests for S. dublin of faecal samples, histological specimens, and material received from emergency slaughter. Particular reference must be made to significant reduction in the number of immunised animals which continued to excrete Salmonellae in their faeces.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology; D002353:Carrier State / Q000382:microbiology / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology / Q000517:prevention & control*; D005243:Feces / Q000382:microbiology; D007114:Immunization / Q000662:veterinary; D012475:Salmonella / Q000276:immunology* / Q000302:isolation & purification; D012481:Salmonella Infections, Animal / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Erfahrungen mit Salmonella-dublin-Lebendimpfstoff zur oralen Anwendung beim Kalb.