Cytogenetic and genetic effects of continuous irradiation at a low exposure rate.
We followed the frequency of chromosome aberrations in bone marrow cells of mice continuously irradiated from a 60Co source at an exposure rate of 4.785 mGy/day (0.5R/day) for 140 days. The frequency of chromosome aberrations increased to 4.8% already at day 10 of irradiation and was stabilized at 2--3% in the period from 60 to 140 days. No increase in the frequency of reciprocal translocations and dominant lethal mutations induced in spermatogonia during irradiation was, however, observed.
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects* / Q000648:ultrastructure; D002869:Chromosome Aberrations; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005720:Gamma Rays; D008297:Male; D051379:Mice; D009154:Mutation; D011247:Pregnancy; D011829:Radiation Dosage; D013093:Spermatogonia / Q000528:radiation effects* / Q000648:ultrastructure; D013094:Spermatozoa / Q000528:radiation effects*; D014178:Translocation, Genetic / Q000528:radiation effects*