The influence of heparin on DNA-distribution patterns of gastric mucosa as obtained by flow cytometry. Preliminary report.
Preliminary results about the influence of Heparin to DNA-distribution patterns of gastric mucosa obtained by flow cytometry are reported. Changes in the configuration of nuclear chromatin, caused by Heparin, are connected with changes in the stainability; thus they are reflected by DNA-distribution patterns. With precaution, some special features in the 4C region of DNA-distribution patterns of gastric mucosa in severe chronic atrophic gastritis and carcinoma are supposed to be attributed to changes in the nuclear chromatin occurring in these diseases.
D000230:Adenocarcinoma / Q000032:analysis; D002453:Cell Cycle; D004247:DNA / Q000032:analysis*; D004273:DNA, Neoplasm / Q000032:analysis; D005456:Fluorescent Dyes; D005470:Fluorometry; D005753:Gastric Mucosa / Q000032:analysis / Q000187:drug effects*; D005756:Gastritis / Q000378:metabolism; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D013274:Stomach Neoplasms / Q000032:analysis
D004273:DNA, Neoplasm; D005456:Fluorescent Dyes; D006493:Heparin; D004247:DNA