Removal of metronidazole by haemodialysis.
The removal of the anti-anaerobic antibiotic metronidazole has been studied in oliguric patients. The drug and its principal metabolite are rapidly removed by haemodialysis so that the plasma concentration quickly falls below the therapeutic range. Hence a further dose of metronidazole would be needed after dialysis to restore an adequate plasma concentration.
D000328:Adult; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000097:blood*; D006435:Renal Dialysis; D014508:Urea / Q000097:blood
D008795:Metronidazole; D014508:Urea; D003404:Creatinine