Leber's optic neuropathy--a cytogenetic study of a family.
The present report describes a family with Leber's optic neuropathy. The cytogenetic findings in this family, as well as some clinical features, are suggestive of a slow viral infection with vertical transmission as a possible cause of the disease.
D000293:Adolescent; D000328:Adult; D002648:Child; D002869:Chromosome Aberrations; D005260:Female; D006580:Genetic Carrier Screening; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D009901:Optic Nerve Diseases / Q000235:genetics* / Q000635:transmission; D010375:Pedigree; D014777:Virus Diseases / Q000635:transmission