title: [Pharmacokinetic model studies of sulfamerazine in domestic mammals. 1. Elimination of Mebacid 200 following intravenous administration to large animals].
abstract: Pharmacokinetic data of sulphamerazine were recorded from eight heads each of calf, adult cattle, horse, and sheep, following intravenous application of Mebacid 200, and mathematical implications were discussed. Exponential excretion was recorded from all species, according to the following equation: c = B x e-k2 x t The most favourable pharmacokinetic parameters were recorded from calf.
mesh_terms: D000818:Animals; D002417:Cattle / Q000378:metabolism*; D005260:Female; D006736:Horses / Q000378:metabolism*; D007275:Injections, Intravenous; D008297:Male; D008954:Models, Biological; D012756:Sheep / Q000378:metabolism*; D013045:Species Specificity; D013416:Sulfamerazine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*
chemical_list: D013416:Sulfamerazine
vernacular_title: Pharmakokinetische Modelluntersuchungen an Sulfamerazin bei Haussäugetieren. 1. Mitteilung: Die Elimination von Mebacid 200 nach intravenöser Applikation beim Grosstier.