[High titre of antibodies to ds-DNA in a case of visceral lupus erythematosus with remission during many years].
In a 21-year-old female patient with lupus erythematosus exacerbation of the disease developed during pregnancy leading to eclampsia and birth of a stillborn fetus. After 10 years of immunosupressive treatment the patient continuing treatment with prednisone had another sucessful pregnancy with birth of a healthy child. Serious organ changes observed in the first years of the disease regressed completelt during 12 years of immunosupressive treatment. Throughout the whole observation period antinuclear antibodies were found in the serum, and in the last year their titre of antobodies to native DNA was high. The necessity of many years of immunosupressive treatment of patients with visceral lupus erythematosus is stressed.
D000328:Adult; D004247:DNA / Q000276:immunology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D013997:Time Factors
D007166:Immunosuppressive Agents; D004247:DNA
Wysokie miano przeciwciał przeciw ds-DNA w przypadku całkowitej wieloleniej remisji tocznia trzewnego.