Wide field specular microscopy. Clinical and research applications.
Through the use of a scanning mirror system, the field of view has been expanded to as much as 0.9 mm in diameter. Both contact and non-contact specular microscopy are possible, each having advantages. In a research application, wound healing in rabbit endothelium is documented by time lapse photography. The study demonstrates the capability to return to an area of interest provided there is a landmark. Clinical applications and advantages over conventional specular microscopy are discussed.
D000818:Animals; D003315:Cornea / Q000033:anatomy & histology / Q000502:physiology*; D004727:Endothelium / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D008853:Microscopy / Q000295:instrumentation / Q000379:methods*; D011817:Rabbits; D014945:Wound Healing