Effect of PMMA and silicone lens materials on normal rabbit corneal endothelium: an in vitro study.
Various silicone elastomer intraocular lens materials were compared to PMMA intraocular lens material to ascertain the relative degree of damage caused by each to the rabbit corneal endothelium in vitro. The soft elastomer materials which had been surface treated by electrical molecular rearrangement appeared to cause the least damage and would therefore possibly be most successful for intraocular lens manufacture.
D000818:Animals; D003315:Cornea / Q000166:cytology; D065306:Corneal Injuries; D004727:Endothelium / Q000166:cytology; D066298:In Vitro Techniques; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008768:Methylmethacrylates / Q000009:adverse effects*; D011817:Rabbits; D012828:Silicones / Q000009:adverse effects*
D008768:Methylmethacrylates; D012828:Silicones