Gross morphological brain differences between Wistar-Kyoto and spontaneously hypertensive rats.
The dissected brains of twelve age-matched rats, six spontaneously hypertensive (SH) and six normotensive (WKY), were examined for quantitative gross morphological differences. The spontaneously hypertensive rats were found to have a significantly smaller mesencephalic region when viewed from the external surfaces. This altered morphology has implications in the stereotaxic placement of lesions or cannulae.
D000818:Animals; D001699:Biometry; D001921:Brain / Q000033:anatomy & histology / Q000473:pathology*; D004210:Dissection; D006973:Hypertension / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains