Congenital stiff-man syndrome.
A second large family with a dominantly inherited benign disorder resembling the stiff-man syndrome is reported. The infants are markedly hypertonic at birth, but their tone becomes almost normal by 3 years of age. Stiffness reappears at adolescence, often precipitated by sudden movement or cold, but remains mild when compared with the sporadic disorder.
D004576:Electromyography; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009122:Muscle Hypertonia / Q000235:genetics; D009127:Muscle Rigidity / Q000235:genetics*; D010375:Pedigree