[Ultrastructure of the substrate of the brain--cerebrospinal fluid barrier in subarachnoid hemorrhage (experimental study)].
A study was made of the ultrastructure of the liquoroencephalic barrier (LEB) and the liquoro-hematic barrier-II (LHB-II). The morphological substrate of LEB--the vascular tunic of the brain and the basal membrane, located on the border of the vascular tunic and the superficial segments of the brain. The presence of the basal membrane determines the selective permeability of LEB. The morphological substrate of LBH-II: the arachnoidendothelial cells of the external (covering) endothelial layer, the substratum of fibrillar structures of the collagen-fiber base, the wall of blood capillaries of the capillary network proper of the vascular tunic. A disturbance of the intactness of the morphological substrates of LEB and LBH-II was found when autogenic blood was infused into the liquor. In the author's opinion, the disturbance of the intactness of LEB may be conductive to the penetration of liquor which contains elements of autogenous blood along the intercellular spaces of the vascular tunic in the superficial segments of the brain, playing a certain role in the development of its oedema.
D000818:Animals; D001099:Arachnoid / Q000648:ultrastructure*; D001812:Blood-Brain Barrier; D001921:Brain / Q000098:blood supply*; D002196:Capillaries / Q000648:ultrastructure; D004195:Disease Models, Animal; D004285:Dogs; D004727:Endothelium / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure; D008854:Microscopy, Electron; D013345:Subarachnoid Hemorrhage / Q000473:pathology*
Ul'trastrultura morfologicheskogo substrata likvoroéntsefalicheskogo bar'era pri subarakhoidal'nom krovoizliianii (éksperimental'noe issledovanie).