[Methodologic problems concerning pharmacology effect on bronchomotricity in asthma (Raw, V/V) (author's transl)].
Study of spirometric, flow-rate and Raw modifications in three groups of 5 to 8 asthmatic patients (stage I or II) before and after acetylcholine and pneumallergen (dust) action is made. The same modifications were studied on the action of dust before and after a chemical protector effect. In two control groups the following parameters were verified: 1) the stability of Raw and V/V (normal subjects: 8); 2) the reproductibility of the acetylcholine bronchospasm, before and after the action of chemical protector (asthmatic patients: 11). Some considerations about the methodology in the practice of bronchomotricity data are submitted.
D000109:Acetylcholine / Q000494:pharmacology; D000293:Adolescent; D000328:Adult; D000403:Airway Resistance / Q000187:drug effects*; D001249:Asthma / Q000503:physiopathology*; D001980:Bronchi / Q000187:drug effects; D001985:Bronchial Provocation Tests / Q000379:methods*; D004391:Dust; D005260:Female; D006801:Humans; D008297:Male; D008449:Maximal Expiratory Flow-Volume Curves; D008875:Middle Aged; D013147:Spirometry; D013806:Theophylline / Q000494:pharmacology
D004391:Dust; D013806:Theophylline; D000109:Acetylcholine
Problèmes méthodologiques pour apprécier l'action pharmacologique sur la bronchomotricité chez les asthmatiques à partir des mesures des Rva et des boucles V/V.