Protein-stimulated exchange of phosphatidylcholine between intact erythrocytes and various membrane systems.
Phosphatidylcholine specific exchange protein from beef liver was found to catalyze the exchange of phosphatidylcholine between intact rat and human erythrocytes and various artificial membranes. Both multilamellar liposomes and single bilayer vesicles prepared from egg lechithin, cholesterol and phosphatidic acid (46:50:4, mol/mol) appeared to be effective phospholipid donor systems. Some merits and disadvantages of the various donor systems are discussed.
D000727:Androgen-Binding Protein; D000818:Animals; D002352:Carrier Proteins / Q000494:pharmacology*; D002417:Cattle; D002784:Cholesterol / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008081:Liposomes / Q000378:metabolism*; D010712:Phosphatidic Acids / Q000097:blood; D010713:Phosphatidylcholines / Q000097:blood* / Q000494:pharmacology*; D049488:Phosphatidylethanolamine Binding Protein; D049294:Phospholipid Transfer Proteins; D060789:Prostatein; D051381:Rats; D060765:Secretoglobins; D014598:Uteroglobin; D060788:Mammaglobin B
D000727:Androgen-Binding Protein; D002352:Carrier Proteins; D002784:Cholesterol; D008081:Liposomes; D010712:Phosphatidic Acids; D010713:Phosphatidylcholines; D049488:Phosphatidylethanolamine Binding Protein; D049294:Phospholipid Transfer Proteins; D060789:Prostatein; D060765:Secretoglobins; D014598:Uteroglobin; C511482:PEBP1 protein, human; C511484:Scgb1d2 protein, rat; C511483:Scgb1d4 protein, rat; C556468:Scgb2a1 protein, rat; D060788:Mammaglobin B