Rapid development of acoustic trauma-induced audiogenic seizure risk in 3 strains of seizure-resistant mice.
Audiogenic seizure risk can be induced in genetically seizure resistant mice by exposure to an intense noise a few days prior to testing for seizure. This experiment demonstrates that the priming induced seizure risk can develop within 6-16 h after priming. It was argued that this finding suggested an alternative hypothesis of priming involving peripheral auditory mechanisms.
D000161:Acoustic Stimulation; D000818:Animals; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D012640:Seizures / Q000503:physiopathology*; D013045:Species Specificity