Effect of potassium on isolated bovine facial and human saphenous veins.
A moderate elevation of external (K0+) (5--10 mM) induces relaxation in bovine facial and human saphenous veins. A further increase of (K0+) leads to biphasic reactions (relaxation followed by contraction). Concentrations of (K0+) higher than about 15 mM cause contractions only. The potassium-induced relaxation may be explained by the stimulation of an electrogenic sodium pump.
D000818:Animals; D002417:Cattle; D005145:Face / Q000098:blood supply; D006801:Humans; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000502:physiology; D011188:Potassium / Q000494:pharmacology*; D012501:Saphenous Vein / Q000187:drug effects; D014680:Veins / Q000187:drug effects
D011188:Potassium