[A case of hypersensitivity to miconazole, econazole, and tolciclate (author's transl)].
In a 60-year-old man a mycosis of hands and feet spreading to other regions of the skin was treated with various modern antimycotic ointments. During treatment the status of the skin did not improve. In a patch-test hypersensitivity (type IV reaction according to Coombs and Gell) to miconazole, econazole and tolciclate was found, which is rare in imidazole derivatives.
D004342:Drug Hypersensitivity / Q000175:diagnosis*; D004464:Econazole / Q000009:adverse effects / Q000627:therapeutic use; D006229:Hand Dermatoses / Q000188:drug therapy; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008825:Miconazole / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy
D007093:Imidazoles; D004464:Econazole; D008825:Miconazole
Ein Fall von Uberempfindlichkeit gegen Miconazol, Econazol und Tolciclat.