title: Pluronic F-68: a promising new skin wound cleanser.
abstract: Pluronic F-68 is a new skin cleanser that has been approved by the Food and Drug Administration for use in humans. In experimental studies, this nonionic detergent prevented the development of infection with no discernible toxicity. We have used Pluronic F-68 clinically in wounds in more than 1,000 patients without demonstrable side effects. As a result of this experience, Pluronic F-68 has replaced all other commercially available scrub solutions for use as a skin wound cleanser in our medical center.
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D003902:Detergents / Q000008:administration & dosage*; D006168:Guinea Pigs; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000187:drug effects; D008297:Male; D010587:Phagocytosis / Q000187:drug effects; D011060:Poloxalene / Q000008:administration & dosage*; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D011817:Rabbits; D012867:Skin / Q000293:injuries*; D013211:Staphylococcus aureus; D013501:Surface-Active Agents / Q000008:administration & dosage*; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000517:prevention & control*
chemical_list: D000891:Anti-Infective Agents, Local; D003902:Detergents; D013501:Surface-Active Agents; D011092:Polyethylene Glycols; D011060:Poloxalene