title: [Experiences with cocarboxylase treatment of alcoholics in ambulatory care].
abstract: A report is given on a treatment carried out in 1971 in 20 adults alcoholic outpatients by means of intravenously administered carboxylase and vitamin B injections. Under abstinence, a reduction in the addiction, psychic activation and physical recuperation without withdrawal symptoms occurred within a few days. Absolute permanent abstinence, which was aimed at, was observed in seven patients, lasting over a period of three to five years. In another six patients is lasted for several months up to two years. In two alcoholics, an improvement of the condition without a longer lasting abstinence was obtained; five patients could hardly be influenced. A subsequent treatment might probably improve the rate of success obtained with this method. The disturbance of the pyruvate metabolism in chronic alcoholism as a cause of the addiction is discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000188:drug therapy*; D000553:Ambulatory Care; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy; D013835:Thiamine Pyrophosphate / Q000627:therapeutic use*
chemical_list: D013835:Thiamine Pyrophosphate
vernacular_title: Erfahrungen mit Kokarboxylase in der ambulanten Behandlung von Alkokolkranken.