title: Some mathematics of recombination: evolution of complexity and genotypic modification in somatic cells - a possible model for aging and cancer effects.
abstract: A plausible discrete time model is proposed, in an effort to explain genotypic modificaton via genetic recombination. The model is used in an effort to explain the evolution of macromolecular complexity. By macromolecular complexity we mean the evolution of a more complex form of a given protein or enzyme from its less-complex ancestors. The model is also used to draw some conclusions concerning the utility of recombination events in aging and carcinogenesis.
mesh_terms: D000375:Aging; D005075:Biological Evolution; D002471:Cell Transformation, Neoplastic; D008433:Mathematics; D008957:Models, Genetic; D011995:Recombination, Genetic