title: Bilateral basal ganglia calcifications visualised on CT scan.
abstract: Thirty-eight cases of basal ganglia calcification imaged on computed axial tomography were reviewed. Most cases were felt to represent senescent calcification. The possibility of a vascular aetiology in this group is discussed. A less common group of patients was identified with calcification secondary to abnormalities in calcium metabolism or radiation therapy. Three cases of basal ganglia calcifications were detected in juvenile epileptic patients receiving chronic anticonvulsants. These cases may be related to abnormalities in calcium metabolism and alkaline phosphatase activity. Clinical evidence of basal ganglia abnormality was generally absent demonstrating the preservation of neuronal pathways in most cases.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000469:Alkaline Phosphatase / Q000097:blood; D000927:Anticonvulsants / Q000009:adverse effects; D001480:Basal Ganglia Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000209:etiology; D002114:Calcinosis / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000201:enzymology; D002128:Calcium Metabolism Disorders / Q000150:complications; D002561:Cerebrovascular Disorders / Q000150:complications; D002648:Child; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D000927:Anticonvulsants; D000469:Alkaline Phosphatase