203Hg binding in the liver and kidney of the frog, Rana tigrina.
Following a single i.p. dose of the radioisotope, 203Hg was found to accumulate in both the high and low molecular weight (MW) fractions of the kidney and liver of the frog. The course of 203Hg appearance in the 2 fractions varied in the liver; 203Hg was exclusively associated with the higher MW fractions at 2 days whereas the radiotracer appeared in both low and high MW fractions at 4 and 7 days after administration. In the kidneys, however, 203Hg was associated with high and low MW fractions at all the intervals studied. Low MW 203Hg binding fraction appeared to be a metallothionein-like substance.
D000818:Animals; D007668:Kidney / Q000032:analysis / Q000378:metabolism*; D008099:Liver / Q000032:analysis / Q000378:metabolism*; D008297:Male; D008628:Mercury / Q000378:metabolism*; D008631:Mercury Radioisotopes; D008668:Metallothionein / Q000378:metabolism; D011898:Ranidae / Q000378:metabolism*
D008631:Mercury Radioisotopes; D008668:Metallothionein; D008628:Mercury