[The dynamics of the drug release from dragées. Part 3: Indometnacin (author's transl)].
The release of indomethacin from dragées has been determined by the following procedures: flow-through chamber method, stationary basket method, and rotating basket method. The maximum of release was reached within 4 hours. The data obtained with the flow-through chamber and the stationary basket method were similar, whereas those yielded by the rotating basket method were somewhat higher. Furthermore, the release rate constant and the half-life period were calculated.
D002626:Chemistry, Pharmaceutical; D007213:Indomethacin / Q000008:administration & dosage*; D013607:Tablets; D013997:Time Factors
D013607:Tablets; D007213:Indomethacin
Dynamik der Arzneimittelabgabe aus Dragées.