High pressure liquid chromatographic determination of sorbitol in bulk sorbitol.
An HPLC procedure for determining sorbitol in bulk sorbitol is described. An Aminex HPX-87 column (Bio-Rad) is used with water as a mobile phase and with a refractive index detector to monitor column eluate. Sorbitol is separated from pentaerythritol, erythritol, ribitol, ethylene glycol, propylene glycol, arabitol, galactitol, mannitol, iditol, and other carbohydrates. The precision of the sorbitol determination, characterized by a 95% confidence interval, corresponds to +/- 1.22%.
D002851:Chromatography, High Pressure Liquid; D011786:Quality Control; D013012:Sorbitol / Q000032:analysis*
D013012:Sorbitol