Experimental plasmacytoma in mice. I. Induction, morphological and biological characteristics.
The induction of plasmacytomas in BALB/c mice by Bayol F or Pristan is described. In some experiments mice treated with Bayol F were antigenically stimulated by repeated injections of allogenic C57BL/6 spleen cells. The incidence of plasmacytoma was 57% in Bayol F treated mice and 59% in the mice subjected to sustained antigenic stimulation. However, the tumors appeared about 6 months earlier in mice stimulated with the allogeneic spleen cells.
D000818:Animals; D000912:Antibodies, Neoplasm / Q000096:biosynthesis; D003651:Decanoates; D007519:Isoantigens / Q000276:immunology; D051379:Mice; D008899:Mineral Oil; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*; D010954:Plasmacytoma / Q000139:chemically induced / Q000276:immunology / Q000473:pathology*; D013154:Spleen / Q000166:cytology
D000912:Antibodies, Neoplasm; D003651:Decanoates; D007519:Isoantigens; D008899:Mineral Oil