[Effect of a substance P analog on sleep deprivation].
The injection of 250 microgram/kg SP-analogue (Lys-Phe-Ile-Gly-Leu-MetNH2) is able to restore the reduced or disturbed delta activities and paradoxical sleep periods of the sleeping EEG in chronically stressed rats.  Thus it has been proved that Substance P, which we would like to term as an ,,regulatory peptide" (equal to regulide) has a modulating function.
D000818:Animals; D003700:Delta Rhythm; D005260:Female; D009043:Motor Activity; D009842:Oligopeptides / Q000494:pharmacology*; D051381:Rats; D012149:Restraint, Physical; D012892:Sleep Deprivation; D014851:Wakefulness / Q000187:drug effects
D009842:Oligopeptides; C027109:lysyl-phenylalanyl-isoleucyl-glycyl-leucyl-methioninamide
Wirkung eines Substanz P-Analogons bei Schlafstörung.