title: Exercise lowers thyroid radioiodine uptake: concise communication.
abstract: The effect of exercise upon the uptake of radioiodine by the thyroid was examined in both rats and humans. Rats that exercised intermittently on a mechanical wheel for a period of 20 days had significantly lower uptake values (p < 0.0001) than sedentary controls. Human volunteers that ran at least ten miles/week had a lower mean 24-hr uptake value (8.0 +/- 2.8%) than nonexercising subjects (14.3 +/- 5.1%, p < 0.01). Other thyroid function studies (thyroxine, triiodothyronine, triiodothyronine resin uptake, thyroid-stimulating hormone) did not differ significantly between the exercising and nonexercising groups. These studies suggest that exercise significantly alters thyroid iodine economy.
mesh_terms: D000328:Adult; D000818:Animals; D005260:Female; D006801:Humans; D007455:Iodine / Q000378:metabolism*; D007457:Iodine Radioisotopes; D008297:Male; D010807:Physical Endurance; D005082:Physical Exertion; D051381:Rats; D013961:Thyroid Gland / Q000378:metabolism*
chemical_list: D007457:Iodine Radioisotopes; D007455:Iodine