[Paraproteinaemic coma in multiple myeloma (author's transl)].
The diagnosis of paraproteinaemic coma was made in 5 out of 74 patients with plasmocytoma. Compared with the other patients these 5 showed a nearly twofold increase of total serum and CSF protein concentration, a higher percentage of plasma cells in sternal marrow and extreme hypergamma-globulinaemia in the immunoelectrophoresis. In both groups CSF and serum amino acid concentrations showed no pathological changes. Psychopathologically the patients with paraproteinaemic coma showed the picture of an exogenous psychosyndrome. Electroencephalography demonstrated moderate general disturbances.
D000368:Aged; D000596:Amino Acids / Q000097:blood / Q000134:cerebrospinal fluid; D001798:Blood Proteins / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D003128:Coma / Q000175:diagnosis / Q000209:etiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D010950:Plasma Cells
D000596:Amino Acids; D001798:Blood Proteins; D002556:Cerebrospinal Fluid Proteins
Das Coma paraproteinaemicum beim multiplen Myelom.