Haemolysis as a means of distinguishing between Leptospira interrogans serovars balcanica and hardjo.
Leptospira interrogans serovar balcanica was haemolytic for washed human, cattle, sheep and possum red blood cells (RBC); serovar hardjo was non-haemolytic. A test for haemolysis may prove useful in the preliminary differentiation of balcanica and hardjo isolates. Balcanica was non-haemolytic for unwashed RBC from human and bovine donors whose serum contained Hebdomadis serogroup antibody. Haemolytic activity tended to disappear with repeated subculture of balcanica.
D000818:Animals; D002417:Cattle; D006461:Hemolysis; D006801:Humans; D007921:Leptospira interrogans / Q000145:classification*; D009893:Opossums; D012703:Serotyping; D012756:Sheep