Nosocomial outbreak of viral hemorrhagic fever caused by Crimean Hemorrhagic fever-Congo virus in Pakistan, January 1976.
This paper describes the clinical, epidemiological, and laboratory investigations undertaken to isolate and identify the etiological agent of a nosocomial cluster of hemorrhagic fever cases due to Crimean hemorrhagic fever (CHR)-Congo virus. Since this virus is usually transmitted by ticks it was surprising that the index case, in a nomadic shepherd, occurred during the winter season when ticks are relatively inactive. These are the first cases of CHF-Congo virus found in humans in Pakistan. Investigations on other biological properties, particularly strain differences and virulence, are being continued at the Islamabad laboratory.
D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D004196:Disease Outbreaks / Q000453:epidemiology*; D005260:Female; D006479:Hemorrhagic Fever, Crimean / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D006801:Humans; D008297:Male; D051379:Mice; D010154:Pakistan
D000914:Antibodies, Viral