title: The effect of diet on some parameters measured in toxicological studies in the rat.
abstract: The bodyweight, food consumption and various biochemical and haematological parameters were measured in, and breeding and histological studies made of, groups of rats fed 6 different diets. All diets acceptably supported reproduction. 1 diet restricted bodyweight gain by 30% and increased plasma alanine transaminase activity. Nephrocalcinosis was seen in females fed diets with a calcium:phosphorous ratio of < 1. Levels of dietary protein were positively correlated with the incidence of renal pelvic dilatation in offspring at 7 weeks of age.
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001835:Body Weight; D004032:Diet / Q000009:adverse effects*; D005260:Female; D008098:Litter Size; D008297:Male; D009397:Nephrocalcinosis / Q000662:veterinary; D009929:Organ Size; D011247:Pregnancy; D051381:Rats / Q000254:growth & development / Q000502:physiology*; D012098:Reproduction; D012376:Rodent Diseases / Q000139:chemically induced; D014116:Toxicology / Q000379:methods