title: Avoiding megamouse experiments.
abstract: A method is described whereby large numbers of individually innocuous substances can be tested for combinations that are carcinogenic or otherwise toxic. The method substantially reduces the number of test animals required to a number far less than would be required for pairwise cross testing.
mesh_terms: D000818:Animals; D004338:Drug Combinations; D051379:Mice; D008962:Models, Theoretical; D014116:Toxicology / Q000379:methods*
chemical_list: D004338:Drug Combinations