Effect of proline on synthesis of collagen by cells in culture.
Chick embryo cells, human epithelial cells, and mouse cells in culture were tested for response to elevated levels of proline in the growth medium. In none of the cell lines tested was the amount of collagen formed stimulated by addition of excess proline.
D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D003094:Collagen / Q000096:biosynthesis*; D004848:Epithelium / Q000187:drug effects / Q000378:metabolism; D005260:Female; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D051379:Mice; D011247:Pregnancy; D011392:Proline / Q000494:pharmacology*
D003094:Collagen; D011392:Proline