HLA and insulin-dependent diabetes in South African negroes.
The HLA antigens of 57 South African negroes with juvenile-onset, insulin-dependent diabetes were determined. The frequency of B8 was increased (29.8% VS 13.9%) as was the frequency of B14 (17.5% vs 6.1%). The frequency of patients with either one of these cross-reactive antigens was significantly increased after correction for the number of antigens tested (45.6% VS 19.2%, P (corrected) < 0.005).
D000328:Adult; D044383:Black People; D003429:Cross Reactions; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D013019:South Africa
D006680:HLA Antigens