Surface membrane enzyme, chemotactic peptide binding activities, and chemotactic responsiveness of rabbit peripheral and peritoneal neutrophils.
The chymotrypsin-like esterase activity of plasma membrane and the ecto-5'nucleotidase and ecto-p-nitrophenyl phosphatase activities in peritoneal neutrophils are 2- and 3-fold higher than peripheral blood neutrophils. The binding of the chemotactic peptide, formyl norleucyl-leucyl-phenyl-alanine to peritoneal neutrophils is 6- to 7-fold higher than to peripheral blood neutrophils. The chemotactic responsiveness of peritoneal neutrophils to the chemotactic peptide is 5-fold greater than peripheral blood neutrophils. However, there was no significant difference in the chemotactic responsiveness to complement component C5a between the blood and peritoneal cells.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology*; D002462:Cell Membrane / Q000201:enzymology*; D002630:Chemotactic Factors / Q000502:physiology; D002634:Chemotaxis, Leukocyte; D009504:Neutrophils / Q000502:physiology; D010455:Peptides / Q000378:metabolism*; D011485:Protein Binding; D011817:Rabbits
D002630:Chemotactic Factors; D010455:Peptides