Heparin necrosis. An anticoagulation syndrome.
Lesions indistinguishable from coumarin necrosis developed in three patients who were given heparin sodium subcutaneously. Two of the patients had received only heparin while another had also received coumarin. Heparin necrosis should be added to the list of complications of anticoagulation therapy.
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D003374:Coumarins / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D007279:Injections, Subcutaneous / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology
D000925:Anticoagulants; D003374:Coumarins; D006493:Heparin