Relationship between I and H antigens. I. A study of the plasma and saliva of a normal population.
The H and I antigens were studied in the plasma and saliva of 52 group O subjects, by hemagglutination inhibition at continuous flow. H plasma substance was detected with one anti-H antibody from a Bh donor. Secretors have more H plasma substance than do non-secretors, but there was no relationship between the amounts of I and H substances in the plasma. On the contrary, the amounts of I substance in the saliva detected by anti-I (Sti) is a function of secretor status. Nonsecretors had a much greater amount of I in saliva than did secretors. These results support the hypothesis that I antigen (detected by anti-I (Sti)) is a part of the substrate of H antigen.
D000017:ABO Blood-Group System; D001789:Blood Group Antigens; D006801:Humans; D007048:I Blood-Group System; D010949:Plasma / Q000276:immunology*; D012463:Saliva / Q000276:immunology* / Q000378:metabolism
D000017:ABO Blood-Group System; D001789:Blood Group Antigens; D007048:I Blood-Group System