title: [State of humoral immunity in epilepsy patients].
abstract: The results of examining the content of immunoglobulins and determining the presence of organ-specific anti-encephalic antibodies in the serum of patients with epilepsy of vascular and non-vascular genesis give one grounds to regard the lowered level of the immunoglobulins as a state of the immune system characteristic of epilepsy and as a factor in whose presence an epileptic seizure starts and develops. The lowering of the immunoglobulin level and the presence of anti-encephalic antibodies mainly against the thalamus in epileptic patients is, undoubtedly, of an importance for disclosing certain links of the disease pathogenesis. It is quite probably, that the data obtained are reflecting one more manifestation of the combined affection of the immunocompetent and the nervous systems.
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001921:Brain / Q000276:immunology*; D002561:Cerebrovascular Disorders / Q000150:complications; D003168:Complement Fixation Tests; D004827:Epilepsy / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D009928:Organ Specificity
chemical_list: D001323:Autoantibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Sostoianie gumoral'nogo immuniteta u bol'nykh épilepsieĭ.