The effect of a TDMAC-heparin bonded aortofemoral shunt on experimental spinal cord injury.
1) Paraplegia or death occurred uniformly in dogs whose descending aorta was cross-clamped for 1 hour. 2) Protection was complete in the experimental model in which a passive shunt was used, provided the flow was greater than 8 ml/kg/min.
D000818:Animals; D001011:Aorta / Q000502:physiology; D001013:Aorta, Thoracic / Q000601:surgery*; D001794:Blood Pressure; D003250:Constriction; D004285:Dogs; D005112:Extracorporeal Circulation / Q000295:instrumentation* / Q000379:methods; D006493:Heparin; D010264:Paraplegia / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D012039:Regional Blood Flow
D006493:Heparin