[An algorithm for calculating HLA haplotype frequency].
The algorithm computes gene- and haplotype frequencies from phenotype data of the HLA system. It is an iterative procedure which finds these frequencies by employing statistical and combinatorial considerations. The probabilities for homozygosity of single genes are used as essential parameters. They are simultaneously computed by the algorithm. These parameters are mainly needed for the evaluation of alleles, whose gene product cannot be determined serologically.
D000483:Alleles; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008285:Major Histocompatibility Complex; D008433:Mathematics; D010641:Phenotype
D006680:HLA Antigens
Ein Algorithmus zur Berechnung der HLA-haplotypfrequenzen.