title: Gas-chromatographic method of analysis for urinary organic acids. I. Retention indices of 155 metabolically important compounds.
abstract: Gas-chromatographic retention indices are given, in terms of methylene units, for 155 metabolically important compounds (mostly organic acids) as trimethylsilyl derivatives on 10% OV-1 and 10% OV-17 columns. Comprehensive references on metabolic diseases that can be diagnosed by detection of these metabolites are cross-indexed to facilitate the use of the methylene-unit list. With the data presented here, it is now possible to diagnose more than 25 well-defined organic acidurias by use of gas chromatography alone.
mesh_terms: D002264:Carboxylic Acids / Q000652:urine*; D002849:Chromatography, Gas / Q000379:methods; D006801:Humans; D008659:Metabolic Diseases / Q000175:diagnosis; D008661:Metabolism, Inborn Errors / Q000175:diagnosis
chemical_list: D002264:Carboxylic Acids