title: [New findings on the effect of azetazolamide (Diamox) on intraocular pressure and acid-base metabolism of the blood following oral administration].
abstract: The reduction in intraocular pressure following administration of 500 mg acetazolamide (Diamox) per os is less pronounced (17%) than was observed after intravenous injection (38%). The occurrence of metabolic acidosis resulting from the administration of Diamox is not time-related to the drop in pressure and is clearly les severe following oral application. This lowers the risk of metabolic decompensation.
mesh_terms: D000086:Acetazolamide / Q000008:administration & dosage / Q000494:pharmacology*; D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000138:Acidosis / Q000139:chemically induced; D000284:Administration, Oral; D001769:Blood; D004305:Dose-Response Relationship, Drug; D005901:Glaucoma / Q000188:drug therapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007429:Intraocular Pressure / Q000187:drug effects*
chemical_list: D000086:Acetazolamide
vernacular_title: Neue Erkenntnisse über die Wirkung von Azetazolamid (Diamox) auf den intraokularen Druck und den Säure-Basenhaushalt des Blutes nach oraler Applikation.