[Functional state of the thyroid gland in oncological patients].
Radiobiochemical test-sets in blood sera of 248 human subjects were used to assess total thyroxine, triiodothyronin, the coefficient of thyroxine activity, triiodothyronin binding ability of blood serum and the activity of the hypophyseal thyreotropic hormone. One hundred and sixteen human subjects showed malignant tumors located in the lung--54, in the stomach--47, in the breast --15.' Control groups comprised 81 practically sound individuals, 23 persons with benign tumors and 28--with chronic nontumor lesions of the stomach. An analysis of the data obtained has evidenced that in patients with malignancies the thyroid hypofunctioning is developing, which is manifested in the lowered level of a physiologically active hormone--triiodothyronin in the peripheral blood. In the presence of a malignancy in the organism the correlations between the hypophysis and thyroid are impaired that seems to be one of the indirect signs of a malignant affection.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000503:physiopathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology*; D013272:Stomach Diseases / Q000503:physiopathology; D013274:Stomach Neoplasms / Q000503:physiopathology; D013961:Thyroid Gland / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000097:blood
D013963:Thyroid Hormones
Funktsional'noe sostoianie shchitovidnoĭ zhelezy u onkologicheskikh bol'nykh.