A modified photometric technique for measuring sebum excretion rate.
Accurate measurement of sebum excretion is necessary to evaluate drugs such as anti-androgen and the new retinoic acid derivatives. Existing techniques are good, but some are inaccurate at high levels of sebum and are time-consuming for technicians. We have therefore, re-examined sebum excretion methodology and have developed a modified photometric technique. This technique, which utilizes a robust, portable machine gives data which are accurate at all levels of sebum production and reduces the technician time of analysis without loss of accuracy or reproducibility.
D006801:Humans; D008722:Methods; D010783:Photometry; D012629:Sebum / Q000378:metabolism*; D012636:Secretory Rate