Unusually strong lipophilicity of 'fat' or 'super' amino-acids, including a new reference value for glycine.
Lipophilic, steric, electronic, and enzyme resistance characteristics of carboranylalanine, adamantylalanine, neopentylglycine and tert-butylglycine are described. The first 2 amino-acids display lipophilicities 2 orders of magnitude higher than tryptophan.
D000596:Amino Acids; D004798:Enzymes / Q000378:metabolism; D005998:Glycine; D008968:Molecular Conformation; D011485:Protein Binding; D013329:Structure-Activity Relationship; D014867:Water
D000596:Amino Acids; D004798:Enzymes; D014867:Water; D005998:Glycine