[Comparative studies of 35S-hemineurine and 35S-thiamine distribution and binding by proteins in the neural structures of the rat brain].
35S-Hemineurine penetrated across the blood-brain barrier more rapidly than 35S-thiamin within the first 30 min after intravenous administration. Within 24 hrs content of 35S-thiamin in the neurones exceeded by 34% its concentration in glia and by 200% -- in myelin fraction. 35S-Hemineurine was bound slightly with brain proteins as compared with thiamin and it was removed at the higher rate from brain regions and subcellular structures.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D005609:Free Radicals; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011485:Protein Binding; D051381:Rats; D013462:Sulfur Radioisotopes; D013831:Thiamine / Q000378:metabolism*; D013844:Thiazoles / Q000378:metabolism*; D013997:Time Factors
D001798:Blood Proteins; D005609:Free Radicals; D009419:Nerve Tissue Proteins; D013462:Sulfur Radioisotopes; D013844:Thiazoles; C012572:2-(4-methyl-1,3-thiazol-5-yl)ethanol; D013831:Thiamine
Sravnitel'nye issledovaniia raspredeleniia i sviazyvaniia 35S-gemineĭrina i 35S-tiamina belkami v neirostrukturakh mozga krys.