[Prolonged neuromuscular blockade during a D. penicillamine-induced myasthenia (author's transl)].
The authors report a D. Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. The disorder was revealed by a postoperative respiratory depression which could be attributed to the aggravation of the neuromuscular blockade by the muscle relaxants. D. Penicillamine-induced myasthenia gravis is now well known. The onset of such an accident after anaesthesia of patient treated with D. Penicillamine is a potential risk. Management of these patients in anaesthesia must be similar to the management of patients with classic myasthenia gravis.
D000328:Adult; D000443:Alcuronium / Q000009:adverse effects; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000139:chemically induced*; D009469:Neuromuscular Junction / Q000187:drug effects*; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use; D011183:Postoperative Complications; D012131:Respiratory Insufficiency / Q000139:chemically induced; D013997:Time Factors
D010396:Penicillamine; D000443:Alcuronium
Curarisation prolongée au cours d'un syndrome myasthénique induit par la D. pénicillamine.