title: Comparative method for the study of structural damage in acoustic trauma.
abstract: The traumatic dose 50 (TD50), similar to the lethal dose (LD50) widely used in pharmacology, was determined in guinea pigs for varying intensities and varying durations of exposure to a band of noise. The method proposed permits the comparison of results in studies of acoustic trauma caused by noises of various characteristics in different species of experimental animals.
mesh_terms: D000818:Animals; D001309:Auditory Threshold; D004195:Disease Models, Animal; D006168:Guinea Pigs; D006317:Hearing Loss, Noise-Induced / Q000503:physiopathology*; D006801:Humans