title: IgM globulin response in Q fever (Coxiella burneti) infections.
abstract: The IgM globulin response has been measured following the onset of primary Q fever infections. A complement fixation test method was used to measure the IgM after separation by ultracentrifugation in a sucrose density gradient. Specific IgM was demonstrable between 2 and 10 wk after onset of symptoms. The test can be used to confirm a recent infection when only a 'convalescent' blood specimen has been collected and will be useful in the assessment of workers' compensation claims.
mesh_terms: D000917:Antibody Formation; D000918:Antibody Specificity; D003168:Complement Fixation Tests; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D011778:Q Fever / Q000276:immunology*; D013997:Time Factors
chemical_list: D007075:Immunoglobulin M