Artificial spawning effected in the fresh water teleost, Cyprinus carpio by clomiphene citrate.
Triweekly i.m. injections of clomiphene citrate (group 1, 25 micrograms/0.5 ml and group II, 50 micrograms/1.0 ml) were administered for a period of 3 months during the preparatory period to female fresh water teleosts exhibiting ovarian recrudescence, while a control group received 0.5 ml of physiological saline throughout the period of experimentation i.e., from February through April. 50 micrograms clomiphene citrate treatment brought about a steady increase in ovarian size, and oocytes began to enlarge and mature and finally ovulation took place in April. This is 4 months ahead of their normal occurrence.
D000818:Animals; D002347:Carps; D002996:Clomiphene / Q000031:analogs & derivatives* / Q000494:pharmacology; D005260:Female; D009865:Oocytes / Q000187:drug effects / Q000502:physiology; D010053:Ovary / Q000187:drug effects / Q000502:physiology; D010060:Ovulation / Q000187:drug effects*
D002996:Clomiphene