Cardiopulmonary arrest after retrobular block.
A 61-year-old woman experienced a cardiopulmonary arrest immediately after the retrobulbar injection of a mixture of 2 ml of 0.5% bupivacaine HCl, 2% mepivacaine HCl, and hyaluronidase. The patient was immediately resuscitated but remained unconscious for a total of 20 minutes. All neurologic deficits resolved completely over the two hours following the cardiopulmonary arrest and no adverse sequelae were noted. We assumed that this cardiopulmonary arrest was precipitated by the local anesthetic being transported via retrograde flow through the ophthalmic artery and then by antegrade flow through the internal carotid artery to the thalamus and other midbrain structures.
D000779:Anesthetics, Local / Q000009:adverse effects*; D002045:Bupivacaine / Q000009:adverse effects; D004338:Drug Combinations; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000009:adverse effects; D008619:Mepivacaine / Q000009:adverse effects; D008875:Middle Aged
D000779:Anesthetics, Local; D004338:Drug Combinations; D008619:Mepivacaine; D006821:Hyaluronoglucosaminidase; D002045:Bupivacaine