title: Incidence of major chromosomal abnormalities in a referred population for suspected chromosomal aberrations: a report of 357 cases.
abstract: The present report describes the cytogenetic findings in 357 cases referred for suspected chromosomal abnormalities because of abnormal clinical features. Chromosomal anomalies were found in 97 (27.2%) of the cases studied. A significantly high rate of chromosomal abnormalities was found in a population with clinical abnormalities in comparison to an unselected population (0.48-0.55%).
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000453:epidemiology*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000235:genetics