The effect of autologous serum, Oradexon and heparin on the cell-mediated immune response in vascular diseases.
The effect of autologous serum, Oradexon and heparin on the leucocyte migration inhibition induced by human vascular extracts was studied in patients with myocardial infarction, peripheral arterial disease and superficial thrombophlebitis. Comparing the effects of autologous serum and these drugs it was established that the reduction of migration inhibition with autologous serum was the lowest in all patients. The effect of Oradexon added to vascular extracts was similar in patients with myocardial infarction and thrombophlebitis. The migration inhibition caused by aorta extract was reduced by heparin in patients with myocardial infarction or obliterating arteriosclerosis, while in patients with thrombophlebitis treated with heparin there was no effect on the inhibition of leucocyte migration caused by vena extract.
D000941:Antigens / Q000276:immunology; D001769:Blood; D001808:Blood Vessels / Q000276:immunology; D002464:Cell Migration Inhibition; D003907:Dexamethasone / Q000494:pharmacology*; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology; D014652:Vascular Diseases / Q000276:immunology*
D000941:Antigens; D003907:Dexamethasone; D006493:Heparin