A comparison of biperiden hydrochloride (Akineton) and benzhexol (Artane) in the treatment of drug-induced Parkinsonism.
A single-blind study compared the clinical efficacy of biperiden hydrochloride (Akineton, Abbott) and benzhexol (Artane, Lederle) in the treatment of neuroleptic-induced Parkinsonism. Both drugs were highly effective and all patients responded favourably to medication. No significant difference was observed between the two treatment groups when individual symptoms were examined.
D000293:Adolescent; D000328:Adult; D001712:Biperiden / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000139:chemically induced / Q000188:drug therapy*; D010880:Piperidines / Q000627:therapeutic use*; D014282:Trihexyphenidyl / Q000627:therapeutic use*
D010880:Piperidines; D001712:Biperiden; D014282:Trihexyphenidyl