title: A mutant of CHO-K1 cells deficient in two nonsequential steps of de novo purine biosynthesis.
mesh_terms: D000582:Amidophosphoribosyltransferase / Q000235:genetics*; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D019733:Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; D002474:Cell-Free System; D006224:Cricetinae; D005816:Genetic Complementation Test; D005973:Glutamine / Q000378:metabolism; D005998:Glycine / Q000031:analogs & derivatives / Q000235:genetics; D008025:Ligases / Q000235:genetics*; D009154:Mutation; D010430:Pentosyltransferases / Q000235:genetics*; D010641:Phenotype; D011687:Purines / Q000096:biosynthesis*; D012265:Ribonucleotides / Q000235:genetics
chemical_list: D011687:Purines; D012265:Ribonucleotides; D005973:Glutamine; D000641:Ammonia; D010430:Pentosyltransferases; D000582:Amidophosphoribosyltransferase; D008025:Ligases; D019733:Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; C022385:phosphoribosylformylglycinamidine synthetase; D005998:Glycine