Ethanol elimination is inherited in the rat.
Ethanol metabolism was shown to be heritable in male and female Sprague-Dawley rats. In addition, the stimulated rate of ethanol elimination following 24 hours of treatment with ethanol was also shown to be heritable. F1 and F2 progeny for the two phenotypes (naive and adapted rates) resembled their selected parents rather than the unselected population.
D000818:Animals; D000431:Ethanol / Q000378:metabolism*; D005260:Female; D007700:Kinetics; D008297:Male; D010641:Phenotype; D051381:Rats; D012737:Sex Factors
D000431:Ethanol