Fluphenazine jaundice. Report of a case.
The management of an agitated schizophrenic was complicated by the onset of severe hepatocellular dysfunction concomitant with the administration of fluphenazine, a drug which has rarely been implicated in phenothiazine jaundice. Since neuroleptics did lead to a dramatic improvement, the patient was treated with an antipsychotic from an alternative drug class. The differential diagnosis, approach to management and natural history are presented, along with a brief review of phenothiazine jaundice, with special emphasis on fluphenazine.
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005476:Fluphenazine / Q000009:adverse effects*; D006801:Humans; D007565:Jaundice / Q000139:chemically induced* / Q000175:diagnosis; D012559:Schizophrenia / Q000188:drug therapy
D005476:Fluphenazine