Tissue analysis for thiazide diuretics.
With the advent of liquid chromatography, identification and quantitation of thiazides by use of milder, non-destructive techniques will be at our disposal. Alternative methods, however, are available. The scheme of analysis presented here--i.e. initial screening with a sensitive but nonspecific colorimetric technique, identification and confirmation with thin-layer chromatography and gas chromatography, and quantitation by gas chromatographic techniques--is a realistic approach to the analysis of diuretics in tissue.
D001581:Benzothiadiazines; D002849:Chromatography, Gas / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D003124:Colorimetry / Q000379:methods; D004232:Diuretics; D006801:Humans; D008099:Liver / Q000032:analysis; D049993:Sodium Chloride Symporter Inhibitors / Q000032:analysis*
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors