Does nutritional status affect benzene induced toxicity and/or leukemia?
Despite similar levels and duration of benzene exposure, toxicological responses of workers are highly variable. Given a similar degree of exposure, why do some workers remain apparently unaffected, while others develop alterations of the hemopoietic system? It is hypothesized that inadequate nutritional status of possibly several nutrients including iron, selenium, methionine and ascorbic acid may enhance susceptibility to adverse effects caused by benzene.
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D001554:Benzene / Q000633:toxicity*; D004041:Dietary Fats / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism; D004285:Dogs; D004734:Energy Metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism; D007938:Leukemia / Q000209:etiology*; D008715:Methionine / Q000378:metabolism; D009747:Nutritional Physiological Phenomena; D012643:Selenium / Q000378:metabolism; D014803:Vitamin B Complex / Q000378:metabolism
D004041:Dietary Fats; D004044:Dietary Proteins; D014803:Vitamin B Complex; D008715:Methionine; D007501:Iron; D012643:Selenium; D001554:Benzene; D001205:Ascorbic Acid