The effect of oxprenolol, acebutolol and propranolol on thyroid hormones in hyperthyroid subjects.
Serum thyroid hormone levels were measured before and during 10 days treatment with acebutolol (400 mg/day), oxprenolol (160 mg/day) and propranolol (160 mg/day) eighteen hyperthyroid patients. A significant change in thyroid hormone concentrations was seen only in the group treated with propranolol. Propranolol should be used in preference to beta-adrenoreceptor blocking drugs with partial agonist activity, in the treatment of hyperthyroidism.
D000070:Acebutolol / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000188:drug therapy*; D008875:Middle Aged; D010096:Oxprenolol / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D013963:Thyroid Hormones / Q000097:blood
D013963:Thyroid Hormones; D010096:Oxprenolol; D000070:Acebutolol; D011433:Propranolol