External stent for repair of secondary tracheomalacia.
Tracheomalacia was created in anesthetized piglets by submucosal resection of 3 to 5 tracheal cartilages. Measurements of airway pressure and flow showed that expiratory airway resistance is maximal at low lung volumes and is significantly increased by creation of the malacic segment. Cervical flexion increases expiratory airway resistance, whereas hyperextension of the neck reduces resistance toward normal. External stenting of the malacic segment reduces expiratory airway resistance, and the combination of external stenting and hyperextension restores airway resistance to normal except at low lung volume. Two patients with secondary tracheomalacia required tracheostomy and could not be decannulated after the indication for the tracheostomy was corrected. Both were successfully decannulated after external stenting of the malacic segment with rib grafts. Postoperative measurements of expiratory pulmonary resistance show a marked decrease from preoperative measurements. External stenting of symptomatic tracheomalacia reduces expiratory airway resistance by supporting and stretching the malacic segment and is preferable to prolonged internal stenting or tracheal resection.
D000403:Airway Resistance; D000818:Animals; D002357:Cartilage Diseases / Q000503:physiopathology / Q000628:therapy*; D002675:Child, Preschool; D004195:Disease Models, Animal; D005260:Female; D005652:Functional Residual Capacity; D006801:Humans; D007223:Infant; D008297:Male; D019736:Prostheses and Implants; D013552:Swine; D014133:Tracheal Diseases / Q000503:physiopathology / Q000628:therapy*