title: Changes in plasma noradrenaline and adrenaline during isometric exercise.
abstract: 1. Plasma noradrenaline and adrenaline were measured radioenzymatically in twelve hypertensive and four normotensive subjects before and during handgrip. In the resting arm (n=11), plasma noradrenaline increased by 17% (P<0.01) and plasma adrenaline by 27% (P<0.001). In the exercising arm, plasma adrenaline increased by 97% (P<0.005) but the mean increase of noradrenaline of 10% was not significant (P>0.1). 2. The noradrenaline response suggests a small and variable sympathetic adrenergic response; the significant difference (P<0.05) in adrenaline responses between resting and exercising arms may reflect local variation in tissue clearance.
mesh_terms: D000328:Adult; D004837:Epinephrine / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000097:blood*; D009638:Norepinephrine / Q000097:blood*; D005082:Physical Exertion
chemical_list: D009638:Norepinephrine; D004837:Epinephrine