A balanced translocation t(4;9) (q35;q12) with a breakpoint within the heterochromatic region of chromosome 9 in a woman with recurrent abortion.
A case of recurrent abortion was found to be associated with the presence in the mother of a balanced translocation between chromosomes 4 and 9. The karyotypes of the proposita was: 46,XX,t(4;9)(q35;q12). The effects of this translocation are discussed in the light of other cases reported in the literature.
D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002905:Chromosomes, Human, 4-5; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D010375:Pedigree; D011247:Pregnancy; D014178:Translocation, Genetic; D014314:Trisomy
D006570:Heterochromatin