The effect of flavoxate on uninhibited detrusor contractions and urinary incontinence in the elderly.
The effect of flavoxate, a smooth muscle relaxant, was investigated in 6 elderly patients with uninhibited detrusor contractions associated with urinary incontinence. Cystometry was done initially to confirm the diagnosis, immediately after an intravenous injection of 100 mg. flavoxate and after 200 mg. flavoxate orally 4 times daily for 7 days. No consistent drug effect could be detected cystometrically and incontinence was unchanged clinically.
D000368:Aged; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000627:therapeutic use*; D005422:Flavoxate / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects*; D014549:Urinary Incontinence / Q000188:drug therapy*
D005419:Flavonoids; D005422:Flavoxate