Preliminary evidence that a dopamine receptor antagonist blocks the prolactin-inhibitory effects of melatonin in anosmic male rats.
Previous studies have shown that daily afternoon injections of melatonin in anosmic male rats result in depressed accessory sex organ weights and serum prolactin levels. The present data indicate that the prolactin-inhibitory effect of melatonin may be mediated via the dopaminergic system.
D000818:Animals; D018492:Dopamine Antagonists; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D000857:Olfaction Disorders / Q000503:physiopathology*; D010868:Pimozide / Q000494:pharmacology; D011388:Prolactin / Q000037:antagonists & inhibitors* / Q000097:blood; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects*
D018492:Dopamine Antagonists; D011954:Receptors, Dopamine; D010868:Pimozide; D011388:Prolactin; D008550:Melatonin