Massive splenomegaly in Northern Zambia. I. Analysis of 344 cases.
Massive splenomegaly is common in Northern Zambia. Nearly 40% of 344 patients were diagnosed as Tropical Splenomegaly Syndrome of malarial origin. Portal hypertension, lymphoreticular and haemopoietic malignancies, and schistosomiasis accounted for another 46%. The common causes of splenomegaly show differences of frequency within Zambia and also between Zambia and other African countries.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D007938:Leukemia / Q000150:complications; D008099:Liver / Q000473:pathology; D008206:Lymphatic Diseases / Q000150:complications; D008218:Lymphocytosis / Q000150:complications; D008223:Lymphoma / Q000150:complications; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D012552:Schistosomiasis / Q000150:complications; D012737:Sex Factors; D013154:Spleen / Q000473:pathology; D013163:Splenomegaly / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D013577:Syndrome; D015024:Zambia