title: Follow-up study with computerized tomography and clinical evaluation 5 to 10 years after surgery for pituitary adenoma.
abstract: This study was based on 24 consecutive patients operated on for pituitary adenoma with suprasellar extension, and treated postoperatively with radiotherapy. The follow-up period was 5 to 10 years. A clinical examination, endocrine evaluation, perimetry, computerized tomography (CT) and sellar roentgenography were performed in 19 of 20 surviving patients. The CT scans revealed four recurrences, while perimetry only showed an increased visual field defect in one patient. Plain sellar films were of no value for diagnosis of recurrence. Prolactin determinations seemed to have a limited value in recurrence diagnosis, but very high levels spoke in favor of a recurrence. Thus, CT was found to be the superior method of diagnosing recurrences. It is proposed that CT be used regularly in the follow-up study of patients operated on for a pituitary adenoma.
mesh_terms: D000236:Adenoma / Q000097:blood / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000000981:diagnostic imaging*; D010911:Pituitary Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000601:surgery*; D011388:Prolactin / Q000097:blood; D014057:Tomography, X-Ray Computed; D058609:Visual Field Tests
chemical_list: D011388:Prolactin