[Different behaviour of street rabies and virus fixé strains in parabiotic rats (author's transl)].
To resolve the problem by which route rabies virus is migrating within the infected organism, coelioanastomosis was performed by operating two albino rats each so that a connection between blood vessels, however not between nerves was established. One of the partners was infected in each case. As soon as one of the parabionts exhibited specific disease, the animals were disconnected again. A comparison of street virus and strains of virus fixé that had been maintained by intracerebral, plantar, and intramuscular passage revealed basic differences. Street virus was found to be transmitted to the non-infected partner almost regularly while virus fixé maintained by intracerebral passage almost never was transmitted. After i.m. passages, plantar virus held an intermediate position.
D000818:Animals; D005260:Female; D008297:Male; D010227:Parabiosis / Q000379:methods; D011818:Rabies / Q000382:microbiology*; D011820:Rabies virus / Q000254:growth & development* / Q000472:pathogenicity; D051381:Rats; D012737:Sex Factors; D014774:Virulence
Uber das unterschiedliche Verhalten von Strassenwut- und Virus fixe-Stämmen bei Parabioseversuchen mit Ratten.