Long term follow-up of serum lipoproteins after jejuno-ileal bypass surgery for massive obesity.
Serum lipoproteins were determined in grossly-obese patients 24 to 59 months after jejuno-ileal bypass surgery. Only minor further changes had occured compared to results obtained after about one year. The main findings were: hypertriglyceridaemia, if present, was normalised; LDL-cholesterol was reduced by about 40 per cent and HDL-cholesterol did not increase in spite of the VLDL-TG normalisation and mean weight losses of about 40 kg for males and 50 kg for females. It is possible that in obesity the well-known negative relationship between VLDL-TG and HDL-cholesterol is disturbed, and that the low HDL concentration represents a primary lipoprotein abnormality directly linked to obesity, rather than an association with the serum TG increase often found in obesity.
D000328:Adult; D002784:Cholesterol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006953:Hyperlipoproteinemia Type IV / Q000209:etiology; D007082:Ileum / Q000601:surgery*; D007583:Jejunum / Q000601:surgery*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000628:therapy*; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood
D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol