Synthesis and antimicrobial activity of some anthranilic acid derivatives.
The synthesis of eight derivatives of anthranilic acid is described. Investigation of their antimicrobial activity showed that four of the compounds, viz; anthranilohydrazide, 3,4-dihydro-4-oxo-1,2,3-benzotriazine, triazine-beta-naphthol adduct and N-phenyl anthranilic acid showed significant antibacterial activity. None of the compounds showed any noticeable antifungal effect.
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis; D001419:Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D062367:ortho-Aminobenzoates / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D062367:ortho-Aminobenzoates