Aminoglycoside antibiotics: thin-layer chromatography, bioautographic detection and quantitative assay.
A sensitive method is described for the identification of aminoglycoside antibiotics, for the detection of agents exhibiting biological activity in the course of fermentation, isolation and purification, and for following their chemical conversion. In the multi-component nebramycin complex the ratio of the factors can be established by the quantitative assay described.
D000617:Aminoglycosides / Q000032:analysis*; D000900:Anti-Bacterial Agents / Q000032:analysis*; D002855:Chromatography, Thin Layer / Q000379:methods*; D009328:Nebramycin / Q000032:analysis; D013678:Technology, Pharmaceutical
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D009328:Nebramycin