Effect of Nocardia rubra cell-wall skeleton on the induction of lung cancer and amyloidosis by 3-methylcholanthrene in rabbits.
Repeated intravenous administrations of oil-attached Nocardia rubra cell-wall skeleton (N. rubra-CWS) prevented the induction of lung cancer by intrabronchial instillations of 3-methylcholanthrene in rabbits. Amyloidosis was seen after giving 3-methylcholanthrene, and the incidence was higher in the N. rubra-CWS administered rabbits than in the controls.
D000236:Adenoma / Q000139:chemically induced / Q000517:prevention & control*; D000686:Amyloidosis / Q000139:chemically induced / Q000517:prevention & control*; D000818:Animals; D002473:Cell Wall / Q000276:immunology; D005260:Female; D006965:Hyperplasia; D007114:Immunization; D008175:Lung Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D008297:Male; D008748:Methylcholanthrene; D009615:Nocardia / Q000276:immunology*; D011817:Rabbits
D008748:Methylcholanthrene