Endoscopic visualization of induced colonic tumors in rats.
The visualization of induced colonic tumors in rats was investigated using either a rigid or flexible endoscope. There was 89% agreement between presence or absence of at least one tumor as visualized at endoscopy and necropsy. The agreement was 83% (p < 0.01) when the exact number of tumors was compared. Neither carcinogens (1,2-dimethylhydrazine or N-methylnitrosourea) nor dietary supplements affected the results.
D000818:Animals; D003110:Colonic Neoplasms / Q000139:chemically induced / Q000175:diagnosis / Q000662:veterinary*; D019723:Endoscopes; D004724:Endoscopy / Q000662:veterinary*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000139:chemically induced / Q000175:diagnosis*