Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
The presence or absence of chlorpropamide-alcohol flushing (CPAF) was not correlated with the classification of diabetes. Five out of twelve patients with juvenile-onset diabetes (JOD) flushed and three out of four patients with maturity-onset diabetes in young people (MODY) did not flush. Consequently, CPAF cannot be used for individual genetic counseling in diabetes mellitus.
D000293:Adolescent; D000328:Adult; D001821:Blushing / Q000187:drug effects*; D002096:C-Peptide / Q000097:blood; D002648:Child; D002747:Chlorpropamide; D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000235:genetics; D000431:Ethanol; D005817:Genetic Counseling; D006801:Humans; D008875:Middle Aged; D012306:Risk; D014044:Tolbutamide
D002096:C-Peptide; D000431:Ethanol; D014044:Tolbutamide; D002747:Chlorpropamide