title: [Proliferation and differentiation processes in the histogenesis of human skeletal muscle tissue].
abstract: A definite relation of processes in DNA, RNA, proteins and glycogene synthesis corresponds to every form of structural organization of the muscular tissue. This has been stated by means of electron microscopic, cytochemical and radioautographic methods. Processes of DNA synthesis predominate at the myoblastic stage. At the myosimplastic stage RNA optic density increases, and promyoblastic proliferation decreases. At the stage of myotubes there is a sharp increase in optic density of proteins, while RNA optic density and intensity of proliferation decreases. At the stage of young muscular fibres, indices demonstrating RNA, portein and glycogene levels increase, proliferation of myogenic elements continues decreasing. Myosatellites of various types appear. Then myones become mature, cytochemical indices on RNA, protein and glycogene contents are high, amount of muscular cells synthesizing DNA is small. During postnatal development RNA optical density in myones decreases, muscular cells synthesizing DNA are not revealed, protein and glycogene contents in myones is high.
mesh_terms: D000293:Adolescent; D002454:Cell Differentiation; D002455:Cell Division; D002648:Child; D002675:Child, Preschool; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008854:Microscopy, Electron; D009132:Muscles / Q000196:embryology* / Q000378:metabolism / Q000648:ultrastructure
vernacular_title: Protsessy proliferatsii i differentsiatsii v gistogeneze skeletnoĭ myshechnoĭ tkani u cheloveka.