title: Elimination of synapses in the developing nervous system.
abstract: Reduction of the number of axons that contact target cells may be a general feature of neural development. This process may underlie the progressively restricted malleability of the maturing nervous system.
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology; D005725:Ganglia, Autonomic / Q000648:ultrastructure; D006801:Humans; D009414:Nerve Growth Factors / Q000502:physiology; D009420:Nervous System / Q000254:growth & development*; D009434:Neural Pathways / Q000254:growth & development; D009469:Neuromuscular Junction / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure*
chemical_list: D009414:Nerve Growth Factors