title: Attempts to produce experimental Eimeria wyomingensis infections in calves.
abstract: Attempts were made to produce repeatable infections with Eimeria wyomingensis in 2- to 4-wk-old calves. From 0.2 million to 10 million sporulated oocysts, or sporocysts from 1 million sporulated oocysts were given orally to 50 calves. Several regimens of flumethasone and dexamethasone at excessive dosage levels were given to some to the oocyst-inoculated calves. Nine of 10 calves given flumethasone and one of 12 calves given dexamethasone treatments died. Of the 41 calves which survived past post-inoculation day 21, 32 had patent infections. The prepatent period in the 32 infections was 13 to 15 (mean 14.2) days and the patent period was 1 to 7 (mean 3.6) days. More fecal oocysts were excreted by calves given sporulated oocysts than those given sporocysts. Calves given corticosteroids passed fewer oocysts than nontreated calves.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology*; D003048:Coccidiosis / Q000469:parasitology / Q000662:veterinary*; D003907:Dexamethasone / Q000494:pharmacology; D004539:Eimeria / Q000254:growth & development; D005243:Feces / Q000469:parasitology; D005443:Flumethasone / Q000494:pharmacology; D013997:Time Factors
chemical_list: D003907:Dexamethasone; D005443:Flumethasone