Infection of neonatal and adult mice with non-passaged influenza viruses. Brief report.
In contrast to adult mouse influenza, infection of neonates with non-passaged influenza viruses (7a and 64c) resulted in approximately 50 per cent mortality. Virus predominated in the upper respiratory tract though the neonatal lung infection was greater than in adults.
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D004195:Disease Models, Animal; D009980:Influenza A virus / Q000254:growth & development / Q000472:pathogenicity*; D008168:Lung / Q000382:microbiology; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000382:microbiology / Q000401:mortality; D014420:Turbinates / Q000382:microbiology; D014774:Virulence