title: Acute disseminated encephalomyelitis after influenza vaccination.
abstract: A 12-year-old, previously healthy boy was seen with typical signs of acute disseminated encephalomyelitis four days after influenza vaccination. Computerized tomography demonstrated an extensive subcortical low-density area in the left cerebral hemisphere. The CSF contained elevated levels of immunoglobulins, especially IgG, and an abnormal kappa:lambda chain ratio. Skin tests for hypersensitivity to egg protein were negative, but reaugmentation of CSF protein and immunoglobulin levels was observed within ten days after skin tests.
mesh_terms: D000208:Acute Disease; D002648:Child; D004679:Encephalomyelitis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D007136:Immunoglobulins; D007252:Influenza Vaccines