Radiation-induced changes in gentamicin pharmacokinetics.
Decreased clearance of i.v. or intratracheally administered gentamicin was observed in rats following single whole-body irradiation. 6 Gy 60Co. reaching its lowest rate on the 7th post-irradiation day. Simultaneously the absorption rate of gentamicin from the lungs was found to be increased.
D000818:Animals; D003037:Cobalt Radioisotopes; D005839:Gentamicins / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D011830:Radiation Effects; D051381:Rats
D003037:Cobalt Radioisotopes; D005839:Gentamicins