Calcific stenosis of a glutaraldehyde-treated porcine bioprosthesis in the aortic position.
The porcine xenograft bioprosthesis is used widely at the present time, although its long-term durability is still being evaluated. Calcification resulting in stenosis of the glutaraldehyde-treated bioprosthesis has been reported infrequently. In the patient described herein, severe calcific stenosis of a porcine xenograft in the aortic position occurred 45 months after implantation. This report emphasizes the life-threatening and rapidly progressive nature of this complication in the long-term survivor after valve replacement.
D000328:Adult; D000818:Animals; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000209:etiology* / Q000601:surgery; D001705:Bioprosthesis / Q000009:adverse effects*; D002114:Calcinosis / Q000150:complications*; D002648:Child; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*