Effect of human alpha 2HS glycoprotein on mouse macrophage function.
alpha 2HS glycoprotein was isolated from normal adult serum. The ability of alpha 2HS glycoprotein to promote the endocytosis of radiolabelled DNA and radiolabelled latex particles by mouse macrophages was investigated. The results using both radiolabelled latex particles and radiolabelled DNA show that alpha 2HS glycoprotein enhances the ability of mouse macrophages to take up these radiolabelled substrates as compared to control cells.
D000328:Adult; D000818:Animals; D004247:DNA; D004705:Endocytosis / Q000187:drug effects; D006023:Glycoproteins / Q000097:blood / Q000276:immunology / Q000494:pharmacology*; D006801:Humans; D007122:Immunoelectrophoresis; D007123:Immunoelectrophoresis, Two-Dimensional; D007840:Latex; D008264:Macrophages / Q000276:immunology*; D051379:Mice
D006023:Glycoproteins; D007840:Latex; D004247:DNA