title: [Main forms and stages in the development of diffuse polyposis of the large intestine (problems of classification)].
abstract: Diffuse polyposis of the large intestine is a hereditary disease involving mostly young people and characterized by a high index of malignization. Previously proposed various classifications of the disease do not reflect completely the numerous important aspects of this pathology. On the basis of macro- and miroscopic studies on 186 operation preparations of the large intestine removed for diffuse polyposis 4 groups of the disease were distinguished: I--the largest group including polyposis with predominance of the cell proliferation processes (various kinds of adenomas--147 observations), II--polyposis with prevalence of secretion processes (juvenile polyps--24 observations), III--polyposis with both signs (10 observations); in this mixed group juvenile polyps alternated with glandular and glandular-villous polyps; group IV included 5 observations with Peuts-Jeghers syndrome.
mesh_terms: D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D007417:Intestinal Polyps / Q000145:classification / Q000209:etiology* / Q000473:pathology; D007420:Intestine, Large / Q000473:pathology; D009367:Neoplasm Staging; D010580:Peutz-Jeghers Syndrome / Q000145:classification
vernacular_title: Osnovnye formy i stadii razvitiia diffuznogo polipoza tolstoĭ kishki (voprosy klassifikatsii).