title: [Process for producing fluorescein for injection purposes (author's transl)].
abstract: The authors report of a process for producing high-purity fluorescein for injection purposes which is characterized by the fact that synthesis-induced by-products are separated from the raw fluorescein, obtained by any process, by means of a clean-up chain consisting in step-by-step monoacetylation in an aqueous-alkaline solution, subsequent diacetylation in pyridine or a pyridine-glacial acetic acid mixture, saponification of the diacetyl product by sodium methoxide in methanol, and precipitation of the fluorescein with anhydrous formic acid.
mesh_terms: D004340:Drug Contamination / Q000517:prevention & control; D005452:Fluoresceins / Q000138:chemical synthesis* / Q000302:isolation & purification; D007267:Injections
chemical_list: D005452:Fluoresceins
vernacular_title: Verfahren zur Herstellung von Fluorescein für Injektionszwecke.