The effect of X-irradiation on the fertility and on the induction of meiotic chromosome rearrangements in mice and their first generation.
The effect of whole-body or local irradiation with X-rays at a dose of 600 R on the induction of chromosomal translocations in the diakinesis metaphase I of the meiosis in treated and F1 males has been examined along with their fertility. Our results show the high percentage of mortality in whole-body irradiated mice. The percentage of the fertility was 25% in whole-body, and 93.7% in locally irradiated males. The testis weight was also reduced. The percentage of chromosomal translocations in diakinesis, metaphase I, or the meiosis was higher after whole-body irradiation than after local irradiation. In F1 males both types of irradiation induced chromosomal translocations.
D000818:Animals; D005298:Fertility / Q000528:radiation effects*; D008297:Male; D008540:Meiosis / Q000528:radiation effects*; D008677:Metaphase; D051379:Mice; D009929:Organ Size; D011829:Radiation Dosage; D013737:Testis / Q000473:pathology; D014178:Translocation, Genetic