title: [Successful hormonal therapy of climacteric disorders].
abstract: 70 women aged 47-66 years, menopausal between 3 and 14 years and suffering from climacteric deficiency symptoms, were treated with estriol succinate. After 5 weeks of treatment the subjective symptoms had greatly subsided. 50 patients had an atrophic vaginal smear prior to treatment. In all cases this improved during therapy. In 8 out of 11 patients no change in the endometrial picture was observed. After the period of treatment a therapy free interval of 4 weeks followed, during which complaints increased in all cases. Besides the morphologic symptoms specially the symptoms flush and sweating were improved by therapy. Psychological complaints were influenced to a lesser degree.
mesh_terms: D002979:Climacteric / Q000187:drug effects*; D004717:Endometrium / Q000187:drug effects; D004964:Estriol / Q000494:pharmacology; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014621:Vagina / Q000166:cytology
chemical_list: D004967:Estrogens; D004964:Estriol
vernacular_title: Erfolgreiche hormonale Therapie klimakterischer Beschwerden.