[Study of serum C3 and C4 fractions in patients with glucose-6-phosphate dehydrogenase deficiency (author's transl)].
Activity of serum C3 and C4 fractions have been measured in 35 individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency and various clinical manifestations. Determination of serum complement was carried out in six cases during an abrupt hemolytic phase; the remaining 29 patients were asymptomatic at the time of laboratory test, but the past history revealed acute hemolytic syndroe in 11 cases. There were no statistical significant differences between C3 and C4 fraction levels of patients with G6PD deficiency and those corresponding to a group of 30 normal controls. Immunoallergic theories causing hemolytic episodes in patients with G6PD deficiency are discussed.
D003176:Complement C3 / Q000032:analysis*; D003181:Complement C4 / Q000032:analysis*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000276:immunology*; D006801:Humans
D003176:Complement C3; D003181:Complement C4
Estudio del C3 y C4 en el déficit en glucosa-6-fosfato deshidrogenasa.