Genetic effects of turmeric and curcumin in mice and rats.
Incorporation of either turmeric (0.5%) or curcumin (0.015%) into diets of mice did not show significant effect on the incidence of micronucleated polychromatic erythrocytes, structural and numerical aberrations in bone-marrow chromosomes, pregnancy rate, number of live and dead embryos, total implants and mutagenic index. Also rats fed cooked diets containing turmeric (0.5 and 0.05%) did not show significant differences in the incidence of chromosomal aberrations in their bone marrow.
D000818:Animals; D001835:Body Weight; D001853:Bone Marrow / Q000187:drug effects; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects; D003212:Condiments; D004912:Erythrocytes / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects; D005313:Fetal Death / Q000139:chemically induced; D005505:Food Coloring Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens; D011247:Pregnancy; D051381:Rats
D005505:Food Coloring Agents; D009153:Mutagens