title: Paraprotein-induced hyperviscosity. A reversible cause of stroke.
abstract: Although the occurrence of the hyperviscosity syndrome with IgG plasma cell leukemia is unusual, it should be considered in the evaluation of patients with focal neurologic deficit with or without a known malignant paraproteinemia. If serum viscosity is elevated, then emergent plasmapheresis should be considered, as it may reverse the neurologic deficit.
mesh_terms: D001809:Blood Viscosity; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000517:prevention & control; D006429:Hemiplegia / Q000209:etiology* / Q000628:therapy; D006801:Humans; D006942:Hypergammaglobulinemia / Q000097:blood* / Q000628:therapy; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis
chemical_list: D007074:Immunoglobulin G