title: Pulmonary and symptom threshold effects of ozone in airline passenger and cockpit crew surrogates.
abstract: Previous studies showed that the ozone concentration for pulmonary and symptom threshold effects in flight attendant surrogates lies between 0.20 and 0.30 ppmv for a 3-h exposure with intermittent treadmill exercise at 1829 m (MSL) stimulated cabin altitude. In the present study of sedentary occupants of the in-flight airline cabin, the same protocol was used except for omitting all treadmill exercise. Symptoms were assessed with a standardized questionnaire. Pulmonary function was assessed using standardized quantitative spirometry. Male smoker and nonsmoker airline passanger and cockpit crew surrogates 40-59 years of age were used. Small but statistically significant displacements occurred in symptoms and in some spirometry parameters. In general, the younger subjects appeared more sensitive to ozone than the older subjects. No significant differences appeared between smokers' and nonsmokers' responses to ozone exposure. It is concluded that the ozone threshold of these sedentary surrogates under these experimental conditions is right at 0.30 ppmv.
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000531:Altitude; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008297:Male; D008875:Middle Aged; D010126:Ozone / Q000009:adverse effects*; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012907:Smoking; D014797:Vital Capacity
chemical_list: D010126:Ozone