Homografts in tympanoplasty: will they be a disaster? an experimental study.
Experimentally transposed homograft ossicles in rats showed behaviour less stables than autografts, all being resorbed within 48 weeks. Using information derived from this and other experimental work in both animals and humans it is predicted that homografts will be unstable in humans in the long term.
D000818:Animals; D004429:Ear Ossicles / Q000637:transplantation*; D007188:Incus / Q000033:anatomy & histology / Q000637:transplantation*; D051381:Rats; D014021:Tissue Preservation; D014184:Transplantation, Homologous; D014433:Tympanoplasty / Q000379:methods*