A death investigation involving quinidine and propranolol.
A death attributed to quinidine-propranolol intoxication is described. Toxicological analysis of the tissues utilized thin layer (TLC) and gas-liquid (GLC) chromatography, ultraviolet (UV) spectrophotometry and gas chromatography-mass spectrometry (GC-MS). Tissue levels for both drugs, along with their chemical ionization mass spectra, are presented.
D000328:Adult; D001923:Brain Chemistry; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D011433:Propranolol / Q000032:analysis / Q000506:poisoning*; D011802:Quinidine / Q000032:analysis / Q000506:poisoning*; D013056:Spectrophotometry, Ultraviolet; D013270:Stomach / Q000032:analysis
D011433:Propranolol; D011802:Quinidine