Aging of the erythrocyte. I. Increase in the microviscosity of cell interior as determined by the spin label method.
By means of the spin labelling technique changes in the microviscosity of the cell interior of density-seperated bovine red blood cells were estimated. An increase in the rotational correlation time of the Tempamine spin label indicated an increase in the microviscosity of the red blood cell interior during in vivo aging. This increase is apparently due to alterations in the electrolyte content and may influence the course of diffusion-limited reactions in the cell.
D000818:Animals; D002417:Cattle; D004058:Diffusion; D004573:Electrolytes; D004905:Erythrocyte Aging; D013113:Spin Labels; D014783:Viscosity
D004573:Electrolytes; D013113:Spin Labels