Studies with a 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP)-resistant L1210 leukemia cell line without cross-resistance to methotrexate.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002460:Cell Line; D004351:Drug Resistance; D005493:Folic Acid Antagonists; D007700:Kinetics; D007939:Leukemia L1210 / Q000201:enzymology / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D011739:Pyrimethamine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology
D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists; C006308:metoprine; D008727:Methotrexate; D011739:Pyrimethamine