Paraprotein-induced hyperviscosity. A reversible cause of stroke.
Although the occurrence of the hyperviscosity syndrome with IgG plasma cell leukemia is unusual, it should be considered in the evaluation of patients with focal neurologic deficit with or without a known malignant paraproteinemia. If serum viscosity is elevated, then emergent plasmapheresis should be considered, as it may reverse the neurologic deficit.
D001809:Blood Viscosity; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000517:prevention & control; D006429:Hemiplegia / Q000209:etiology* / Q000628:therapy; D006801:Humans; D006942:Hypergammaglobulinemia / Q000097:blood* / Q000628:therapy; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis
D007074:Immunoglobulin G