title: Deep T wave inversions after value replacement for chronic aortic regurgitation: possible conversion from a diastolic to systolic overload pattern.
abstract: This report describes deep, non-infarctional T wave inversions occurring after aortic valve replacement for severe, chronic aortic regurgitation. These new T wave inversions may reflect the effect of abruptly converting a severe preoperative diastolic overload state to a post-operative systolic overload state caused by mild or moderate prosthetic valve stenosis. Other factors such as non-infarctional intra-operative ischemia or mechanical injury may also play a role in the pathogenesis of these repolarization abnormalities. The T wave changes were most marked in the immediate post-operative period and tended to regress in the weeks and months following value replacement. The differential diagnosis of these ST-T changes is discussed.
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000601:surgery*; D002908:Chronic Disease; D003971:Diastole; D004562:Electrocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013599:Systole