New phenotypic marker for lipopolysaccharide responsiveness.
Lipopolysaccharide-enhanced secretion of non-immunoglobulin proteins by bone marrow cells derived from responder, nonresponder, and low-responder mouse strains did not precisely correlate with the lipopolysaccharide responsiveness assessment based on the mitogenic reactivity of splenocytes. These findings suggest that enhancement of secretion of non-immunoglobulin protein may be useful for further characterization of lipopolysaccharide responsiveness.
D000818:Animals; D001853:Bone Marrow / Q000276:immunology / Q000378:metabolism; D002874:Chromosome Mapping; D008070:Lipopolysaccharides / Q000494:pharmacology*; D051379:Mice; D008809:Mice, Inbred C3H / Q000235:genetics*; D008810:Mice, Inbred C57BL / Q000235:genetics*; D008808:Mice, Inbred CBA / Q000235:genetics*; D010641:Phenotype; D011506:Proteins / Q000378:metabolism
D008070:Lipopolysaccharides; D011506:Proteins