Labelling of blood platelets with stable tracers.
Half-time values of platelets labelled with stable rubidium are compared to those of platelets labelled with Cr51. Platelets labelled with stable rubidium are assayed by a very simple version of the X-Ray fluorescence equipment. The mean quantity of rubidium incorporated by the cells is of about some microgram Rb per ml blood. The in vitro half-time of human Rb labelled platelets stored at 22 degrees C is 41.2 +/- 3h compared with the value 44.8 +/- 3h for platelets labelled with Cr51, as deduced by six experiments. The in vivo half-time of rabbit platelets labelled with stable rubidium is 22 +/- 3h compared with the value 18 +/- 3h of platelets labelled with Cr51; ten experiments were carried out.
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D002860:Chromium Radioisotopes; D006207:Half-Life; D006801:Humans; D011817:Rabbits; D012413:Rubidium
D002860:Chromium Radioisotopes; D012413:Rubidium