Unusual effects of metrizamide lumbar myelography. Constellation of aseptic meningitis, arachnoiditis, communicating hydrocephalus, and Guillaine-Barré syndrome.
A clinical constellation of aseptic meningitis, arachnoiditis, communicating hydrocephalus, and a Guillain-Barré syndrome occurred following lumbar myelography with metrizamide. To our knowledge, Guillain-Barré syndrome has not been previously described following myelography with any contrast agent. Meningeal reactions and hydrocephalus have been reported with other agents, but this is the first instance with metrizamide.
D000368:Aged; D001100:Arachnoiditis / Q000139:chemically induced*; D006801:Humans; D006849:Hydrocephalus / Q000139:chemically induced*; D007405:Intervertebral Disc Displacement / Q000000981:diagnostic imaging; D008297:Male; D008581:Meningitis / Q000139:chemically induced*; D008582:Meningitis, Aseptic / Q000139:chemically induced*; D008793:Metrizamide / Q000009:adverse effects*; D009192:Myelography / Q000009:adverse effects*; D011129:Polyradiculoneuropathy / Q000139:chemically induced*; D014057:Tomography, X-Ray Computed
D008793:Metrizamide