Cimetidine for peptic ulcer in patients with arthritis.
Patients taking anti-inflammatory drugs for arthritis are prone to dyspepsia, and management of peptic ulcer is difficult because surgery is poorly tolerated. In this open study cimetidine treatment was associated with ulcer healing in 17 out of 21 patients with arthritis even when anti-inflammatory treatment was continued. Remission was maintained for 1 year by continued cimetidine therapy.
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D001168:Arthritis / Q000150:complications*; D002927:Cimetidine / Q000627:therapeutic use*; D004724:Endoscopy; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000209:etiology; D013997:Time Factors
D000893:Anti-Inflammatory Agents; D006146:Guanidines; D002927:Cimetidine