Pure red cell aplasia and the syndrome of multiple endocrine gland insufficiency.
A 26-year-old female with the syndrome of multiple endocrine gland insufficiency developed pure red cell aplasia. A clinical remission of the pure red cell aplasia was induced with prednisone and cyclophosphamide therapy. The occurrence of these two disorders in a single patient allows speculation on a possible defect in immune surveillance leading to multisystemic immune dysfunction in this patient.
D000293:Adolescent; D000309:Adrenal Insufficiency / Q000150:complications; D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004700:Endocrine System Diseases / Q000150:complications*; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000150:complications; D007011:Hypoparathyroidism / Q000150:complications; D011241:Prednisone / Q000627:therapeutic use
D003520:Cyclophosphamide; D011241:Prednisone