title: ["Clinical clearance" and "weekly clearance" of urea in periodical hemodialytic treatment].
abstract: Starting from the hypothesis that small molecules are freely diffusible, a simple formula is proposed for the determination of real ureic clearance during dialysis. This automatically allows for all variables (blood flow and flow of the dialysing solution, temperature, physical and/or chemical state of the membrane, level of solute concentration, transmembrane pressure, etc.). On the basis of this formula, a calculation system is also proposed for assessing weekly ureic clearance levels and hence the real efficiency of treatment. This system may also be applied to peritoneal dialysis and permits optimisation of substitutive treatment. It is thus easier to select the best filter and rhythms for each patient.
mesh_terms: D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy*; D006435:Renal Dialysis; D014508:Urea / Q000378:metabolism*; D014511:Uremia / Q000378:metabolism / Q000628:therapy*
chemical_list: D014508:Urea
vernacular_title: "Clearance clinica" e "clearance settimanale" dell'urea nel trattamento emodialitico periodico.