Genetic relatedness of the neuramindase of influenza A strains Nav2, Nav3, and Nav6.
By molecular hybridization and by neuraminidase inhibition tests it is shown that all influenza A strains tested carrying an Nav3 or Nav2 neuraminidase (NA) are genetically highly related in their NA genes and cross-react serologically with specific antineuraminidase sera. The Nav6 strains exhibit a very low RNase protection after hybridization and do not cross-react serologically with Nav2 or Nav3 strains. Thus, the Nav2 and Nav3 strains comprise one group which is distinct from that of Nav6 strains.
D003429:Cross Reactions; D005814:Genes, Viral; D009980:Influenza A virus / Q000201:enzymology / Q000235:genetics*; D009439:Neuraminidase / Q000235:genetics* / Q000276:immunology; D009693:Nucleic Acid Hybridization
D009439:Neuraminidase