Cardiac function and hemodynamic parameters after pentaerythritol tetranitrate. Assessment by new noninvasive radionuclide technique.
The availability of a relatively small computer with programming providing multiple gated acquisition capability (MUGA) permits the measurement of ejection fraction and evaluation of ventricular wall motion without the need for invasive techniques. It is probable that the various nitrates available--nitroglycerin, PETN and isosorbide dinitrate--have somewhat different hemodynamic effects and that the radionuclide technique can assist in determining these differences and may help to predict which agents might be most appropriate in specific situations.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003201:Computers; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010417:Pentaerythritol Tetranitrate / Q000494:pharmacology*; D011877:Radionuclide Imaging; D013667:Technetium
D010417:Pentaerythritol Tetranitrate; D013667:Technetium