The autoradiographic localization of paraquat in the lung.
Paraquat poisoning in mammals results in a characteristic lung lesion manifested principally as progressive pulmonary fibrosis. Paraquat is actively concentrated into the lung but the site of uptake remains undefined. A method is described for the autoradiographic localization of paraquat. Preliminary evidence for the site of uptake implicates the bronchiolar epithelium.
D000818:Animals; D001345:Autoradiography; D001980:Bronchi / Q000032:analysis; D002250:Carbon Radioisotopes; D004848:Epithelium / Q000032:analysis; D005260:Female; D008168:Lung / Q000032:analysis*; D010269:Paraquat / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D002250:Carbon Radioisotopes; D010269:Paraquat