Racial contrasts in cardiovascular response tests for children from a total community.
Cardiovascular risk factors in childhood were assessed by re-examining a random sample of 278 children stratified by diastolic blood pressure (BP), obtained from 3524 children aged 7-15 years in an entire geographic biracial community (Bogalusa). Re-examination included plasma renin and serum electrolytes, 24-hour urine electrolytes, heart rates, and BP at rest and in response to standardized physical stresses (orthostatic, isometric handgrip, and cold pressor tests). The BP responses in these tests were not increased in the high BP strata, which argues against a prevailing labile phase in early essential hypertension. Black children tended toward larger BP responses than whites. In black boys of the high BP stratum (n = 25), systolic supine or stressed BP were higher than for other race-sex groups; these pressures were associated negatively with plasma renin activity, which was low. White children in the high BP strata had increased heart rates, possibly indicating hyperkinetic circulation. These findings indicate that multiple mechanisms operate to contol BP at different intensities for black and white children.
D000293:Adolescent; D044383:Black People; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D010808:Physical Examination; D012146:Rest; D012306:Risk; D013599:Systole; D044465:White People