Serum phospholipid fractionation after the use of long-acting progestational contraceptives.
The effect of the two long-acting progestational contraceptive injection, depot-medroxyprogesterone acetate (DMPA) and norethisterone onenathate (NET-OEN), on blood phospholipid fractions were studied in eighteen women. The post-injection results showed a significant increase in total serum phospholipids, serum lecithin and serum cephalins. Serum lysolecithin was significantly decreased while serum sphingomyelin showed no significant change. The mechanisms responsible for these phospholipid changes remain somewhat unclear. However deranged liver function may share in its explanation.
D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000502:physiology; D008525:Medroxyprogesterone / Q000494:pharmacology*; D009640:Norethindrone / Q000494:pharmacology*; D010743:Phospholipids / Q000097:blood*
D010743:Phospholipids; D008525:Medroxyprogesterone; D009640:Norethindrone