[Ultrastructural changes in the undamaged areas of the myocardium in rats with ischaemic-metabolic cardiomyopathy (author's transl)].
The ultrastructural changes in the undamaged areas of the myocardium in rats with ischemic-metabolic cardiomyopathy induced by treatment with Na2HPO4, Sopolcort H, and adrenalin are studied. In the cardiac muscle cells that seem to be uninjured, by light-microscopic investigation considerable damages of the mitochondria, sarcoplasmatic reticulum, myofibrils and the intercalated discs are found. These damages show that the there are a heavy hypoxia and metabolic disturbances outside the infarcted zones. Probably, they have certain significance for the progression of the morbid process in the myocardium.
D000305:Adrenal Cortex Hormones; D000818:Animals; D003327:Coronary Disease / Q000139:chemically induced / Q000473:pathology*; D004837:Epinephrine; D008297:Male; D008854:Microscopy, Electron; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009206:Myocardium / Q000648:ultrastructure*; D009210:Myofibrils / Q000648:ultrastructure; D051381:Rats; D012519:Sarcoplasmic Reticulum / Q000648:ultrastructure
D000305:Adrenal Cortex Hormones; D004837:Epinephrine
Ultrastrukturelle Veränderungen des Myokards von Ratten mit experimenteller ischämisch-metabolischer Myokardiopathie.