Abnormal pattern of the rough endoplasmic reticulum of plasma cells in multiple myeloma with multiple concentric lamellar bodies and "single sac loops".
A patient with IgG myeloma showed a highly abnormal pattern of the rough endoplasmic reticulum (RER) with multiple concentric lamellar bodies and "single sac loops". This abnormal pattern might be due to either a complete rearrangement of the architecture within the cell, and/or a pathology in the wall of the sacs of RER.
D004721:Endoplasmic Reticulum / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000648:ultrastructure*; D009940:Organoids / Q000648:ultrastructure*; D010950:Plasma Cells / Q000648:ultrastructure*