[3H]3-O-methyl-D-glucose transport from blood into the lumina of the seminiferous and epididymal tubules in intact and vasectomized hamsters.
The investigation demonstrated a restriction of [3H]3-O-methyl-D-glucose ([3H]3-OMG) net transport into seminiferous tubule fluid. Net transport of [3H]3-OMG into the cauda epididymidal tubule was even more limited. By 4 months after vasectomy, there was no statistical difference in the net transport of the isotope into the seminiferous tubule fluid, but there was a significant increase in net transport into cauda epididymidal fluid. These results demonstrate that the blood-epididymal barrier can be even more restrictive to molecular transport than the blood-testis barrier and that vasectomy can have subtle effects on characteristics of molecular transport in the cauda epididymidis.
D000818:Animals; D001814:Blood-Testis Barrier; D001826:Body Fluids / Q000378:metabolism; D006224:Cricetinae; D004822:Epididymis / Q000378:metabolism*; D008297:Male; D008647:Mesocricetus; D008757:Methylglucosides / Q000378:metabolism*; D008759:Methylglycosides / Q000378:metabolism*; D012671:Seminiferous Tubules / Q000378:metabolism*; D013737:Testis / Q000378:metabolism*; D014659:Vasectomy
D008757:Methylglucosides; D008759:Methylglycosides; C027020:methylglucoside