Small renal adenocarcinoma with metastases.
A case of a 9 mm. renal adenocarcinoma with widespread metastases, including multiple osteoblastic metastases, is presented. An extensive clinical investigation to identify a primary lesion in this patient was negative, including prostatic biopsy, serum electrophoresis, bone marrow biopsy, excretory urography, renal arteriography and abdominal computerized axial tomography scan. Examination at autopsy documented a small adenocarcinoma of the right kidney with local capsular invasion and metastases to the lungs, para-aortic lymph nodes and vertebrae. The differential pathologic and clincal features separating renal adenoma from adenocarcinoma are discussed.
D000230:Adenocarcinoma / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000473:pathology / Q000556:secondary*