[Specific erythrocyte adherence reaction: an index of the malignant potentials of noninvasive tumors of the human urothelium].
Histological sections of 30 primary transitional cell tumors (15 papillomas, 2 cancers of the first, 3--the second and 10--the third stage) were employed for the reaction of specific adherenci of erythrocytes to defect ABO(H)-agtigens. The latter were absent in invasive cancers of grade III as well as in the noninvasive eptiheliomas which were associated with invasive recurrences during 2 years. To a considerable or full extent the antigens remained in tumors following the removal of which invasive recurrences beveloped accordingly in 3 years or later. It is suggeested that changing (loss) of ABO(H)-antigenic differentiation in urothelial tumors precedes the onset of invasion at least by 2--3 years.
D000017:ABO Blood-Group System / Q000276:immunology; D000951:Antigens, Neoplasm / Q000032:analysis; D002295:Carcinoma, Transitional Cell / Q000276:immunology; D002448:Cell Adhesion; D004848:Epithelium / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000276:immunology; D010212:Papilloma / Q000276:immunology; D001749:Urinary Bladder Neoplasms / Q000276:immunology*; D014551:Urinary Tract / Q000276:immunology*
D000017:ABO Blood-Group System; D000951:Antigens, Neoplasm
Reaktsiia spetsificheskogo prilipaniia éritrotsitov--pokazatel' zlokachestvennykh potentsiĭ neinvazivnykh opukholeĭ uroteliia cheloveka.