[Functional results of transsphenoidal selective adenomectomy in acromegaly (40 cases)].
Forty acromegalic patients were investigated before, during and after transsphenoidal selective adenomectomy. Pre- and post-operative studies were based on HGH basal levels, OGTT, TRH and LRH stimulation tests, while HGH plasma variations were measured during operation. Selective adenomectomy normalized HGH levels in 70% of all cases (89.5% in grades I-II and 52.4% in grades III-IV); moreover in these cases, OGTT documented normal control of GH secretion. Per-operative GH levels evolution proved to be of pronostic value. Stimulation tests demonstrated normal regulation of other pituitary functions.
D000172:Acromegaly / Q000209:etiology* / Q000628:therapy*; D000236:Adenoma / Q000150:complications / Q000378:metabolism / Q000601:surgery*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications / Q000378:metabolism / Q000601:surgery*; D013100:Sphenoid Bone
Résultats fonctionnels de l'adénomectomie sélective transsphénoïdale dans l'acromégalie.