title: Induction of anaesthesia with etomidate: haemodynamic study of 36 patients.
abstract: The haemodynamic effects of anaesthetic induction with i.v. etomidate have been assessed in 36 patients. The variables studied were recorded under basal conditions and 3 and 10 min after induction, before surgical stimulus. There was a reduction in cardiac output, stroke volume and arterial pressure, and a compensating increase in heart rate. Pulmonary arterial pressure and vascular resistance, central venous pressure and pulmonary capillary wedge pressure were virtually unchanged. Although etomidate has a negative inotropic effect, the variables which were depressed remained at all times within acceptable limits.
mesh_terms: D000771:Anesthesia, Intravenous / Q000379:methods*; D003864:Depression, Chemical; D005045:Etomidate / Q000494:pharmacology*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D013514:Surgical Procedures, Operative; D013997:Time Factors
chemical_list: D007093:Imidazoles; D005045:Etomidate