title: Induction of nuclear androgen-binding sites in epithelium of the embryonic urinary bladder by mesenchyme of the urogenital sinus of embryonic mice.
abstract: Mesenchyme of the embryonic urogenital sinus induces epithelium of the embryonic urinary bladder to form prostatic acini. The induced glandular epithelium exhibits nuclear androgen-binding sites, as demonstrated autoradiographically. This suggests that the expression of androgen receptor activity in an epithelium is dependent upon the mesenchyme with which it is associated during development.
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D013196:Dihydrotestosterone / Q000378:metabolism; D004622:Embryo, Mammalian / Q000502:physiology; D004848:Epithelium / Q000378:metabolism; D005260:Female; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy; D011467:Prostate / Q000196:embryology; D011944:Receptors, Androgen / Q000378:metabolism*; D011987:Receptors, Steroid / Q000378:metabolism*; D014184:Transplantation, Homologous; D001743:Urinary Bladder / Q000378:metabolism*; D014566:Urogenital System / Q000196:embryology / Q000637:transplantation*
chemical_list: D011944:Receptors, Androgen; D011987:Receptors, Steroid; D013196:Dihydrotestosterone