The cerebellar pacemaker for intractable behavioral disorders and epilepsy: follow-up report.
Thirty-eight patients who were intractably ill with a variety of behavioral disorders have been treated at Tulane with a chronically implanted cerebellar pacemaker. Included in the series ara schizophrenics, depressives, epileptics with behavioral pathology, and patients with severe organic brain pathology. The patients who have responded best to the treatment are those with depression, those with behavioral pathology consequent to epilepsy, and those with psychotic behavior consequent to structural brain damage. Results obtained in the chronic schizophrenic patients have been less favorable. The follow-up period ranges from a few months to 27 months. Overall, the results continue to be encouraging. Twenty-one percent of the patient group displayed structural evidence of cerebellar pathology that was not detected before operation, a finding which suggests that cerebellar damage may induce psychotic behavior.
D002531:Cerebellum / Q000503:physiopathology*; D003866:Depressive Disorder / Q000628:therapy; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004827:Epilepsy / Q000503:physiopathology / Q000628:therapy*; D005072:Evoked Potentials, Auditory; D005500:Follow-Up Studies; D006801:Humans; D019965:Neurocognitive Disorders / Q000628:therapy; D012559:Schizophrenia / Q000628:therapy; D012920:Social Behavior Disorders / Q000503:physiopathology / Q000628:therapy*