D-Lactic acidosis in a boy with short bowel syndrome.
Metabolic acidosis in a 3-year-old child with short bowel syndrome led to the discovery of massive D-lactic aciduria. After normalisation of the intestinal bacterial flora, D-lactate disappeared together with the acidosis. Dysbacteriosis with excessive production of D-lactate by intestinal bacteria (unidentified) and subsequent absorption explains this unusual cause of metabolic acidosis.
D000138:Acidosis / Q000209:etiology*; D002675:Child, Preschool; D006801:Humans; D007422:Intestines / Q000382:microbiology; D007773:Lactates / Q000652:urine*; D008286:Malabsorption Syndromes / Q000150:complications*; D008297:Male; D012778:Short Bowel Syndrome / Q000150:complications* / Q000382:microbiology
D007773:Lactates