title: Repeated doses of suxamethonium.
abstract: Repeated sub-apnoeic doses of suxamethonium produce increased neuromuscular block in a hand muscle, measured by integrated electromyogram. The response to the initial dose varies widely between patients. More than 50% of patients showed evidence of non-depolarising block after one dose of suxamethonium. There was a variation between the response of the hand muscle and respiratory muscles.
mesh_terms: D002648:Child; D004305:Dose-Response Relationship, Drug; D004576:Electromyography; D006801:Humans; D013390:Succinylcholine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D013390:Succinylcholine