Esophageal reconstruction with free jejunal grafts: an experimental study.
Replacement of a long segment of esophagus for esophageal atresia or severe stenosis remains a special problem in children. The following studies were designed to test the hypothesis that a section of small bowel without serosa could survive as a free autologous transplant to replace part of the mediastinal esophagus. Laparotomy was performed in 20 adult cats, a loop of small bowel was resected and an end-to-end jejunojejunostomy was completed. The serosa of the resected bowel was removed and the mucosa-muscularis graft was used to replace a segment of the middle esophagus that was resected via a right thoracotomy. The interposed graft was entirely wrapped with adjacent skeletal muscle flaps. Postoperative studies include barium swallow and cine esophagograms, histology and blood vessel casts. Results are presented which show anatomical and functional survival of 16 grafts without blood vessel anastomoses or intrinsic vascular pedicles.
D000818:Animals; D002415:Cats; D004933:Esophageal Atresia / Q000601:surgery; D004940:Esophageal Stenosis / Q000601:surgery; D004944:Esophagoplasty / Q000379:methods*; D004947:Esophagus / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D007583:Jejunum / Q000637:transplantation*; D011183:Postoperative Complications; D011859:Radiography; D014182:Transplantation, Autologous