[Outcome of surgery in 300 cases of hyperthyroidism, including 40 with cardiotoxicity (author's transl)].
Of 300 patients who underwent subtotal thyroidectomy, 204 had Graves' disease, 52 solitary toxic goiter and 39 multinodular toxic goiter. Cardiotoxicity was present in 40 cases. Immediate post-operative complications could be avoided by the use of propranolol, neuroleptanalgesia and, in a few very severe cases, hypothermia. Long term results were satisfactory, even after surgery for diffuse hyperthyroidism. Relapses occurred in only 2%, and permanent hypothyroidsm developed within 3 years in only 18% of patients with Graves' disease, this being due to the preservation of 6 grams of thyroid tissue systematically measured by comparative double-weighing. The authors insist on the value of this technique, guess evaluation being unreliable. Cardiotoxicity did not increase post-operative complications, nor the risk of permanent hypothyroidism. The good results obtained should encourage wider surgical indications for the treatment of Graves' disease, solitary toxic goiter or multinodular toxic goiter.
D005260:Female; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000601:surgery*; D007037:Hypothyroidism / Q000209:etiology; D008297:Male; D011183:Postoperative Complications
Evolution de 300 hyperthyroïdies opĕrĕes dont 40 cardiothyrĕoses.