Determination of orotic acid in children's urine.
A reliable method is described for the determination of urinary orotic acid. The orotic acid is separated quickly and easily from the urine by anion exchange chromatography. Reference values are reported for children. The method is suitable for the differentiation of those inherited metabolic defects that lead to hyperammonemia.
D000293:Adolescent; D000641:Ammonia / Q000097:blood; D002648:Child; D002675:Child, Preschool; D002852:Chromatography, Ion Exchange / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009963:Orotic Acid / Q000652:urine*
D009963:Orotic Acid; D000641:Ammonia