Neuronal ceroid-lipofuscinosis in older dachshunds.
A lysosomal storage disease with accumulation of periodic acid-Schiff- and Sudan black-positive autofluorescent granules in neurons occurred in one 5 1/2- and one 7-year-old dachshund. Ultrastructurally, the storage material consisted of membranous material arranged in stacks and fingerprint patterns. The disease was defined as ceroid-lipofuscinosis, and resembled a previously reported case in an adult dachshund.
D000818:Animals; D002493:Central Nervous System Diseases / Q000473:pathology / Q000662:veterinary*; D002531:Cerebellum / Q000648:ultrastructure; D002566:Ceroid; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008062:Lipofuscin; D008297:Male; D010859:Pigmentation Disorders / Q000473:pathology / Q000662:veterinary*; D010860:Pigments, Biological
D002566:Ceroid; D008062:Lipofuscin; D010860:Pigments, Biological