Toxicologic enhancement by a combination of drugs which deplete hepatic glutathione: acetaminophen and doxorubicin (adriamycin).
D000082:Acetaminophen / Q000633:toxicity*; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D004317:Doxorubicin / Q000633:toxicity*; D004357:Drug Synergism; D005978:Glutathione / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR
D000082:Acetaminophen; D004317:Doxorubicin; D000410:Alanine Transaminase; D005978:Glutathione