[Cooperative study of bacterial incidence and susceptibility to cefamandole and other antibiotics (author's transl)].
A total of 44 medical centers participated in a cooperative study on nosocomial infections. Percentages of Gram-negative, Gram-positive and anaerobic germs isolated during 30 alternate-days for 3 months were 80.35 percent, 17.25 percent and 0.52 percent, respectively. Activity of cefamandole and cefalotin against Gram-positive bacteria was very similar, and both antibiotics showed a low number of resistances. On the contrary, against Gram-negative strains the activity of cefamandole was definitely superior to that of cefalothin, but it was similar when compared to that of gentamicin. In many instances, cefamandole may be a valid alternative in treating hospital-acquired infections (except for Pseudomonas).
D001419:Bacteria / Q000187:drug effects*; D002435:Cefamandole / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D002512:Cephalothin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D005839:Gentamicins / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D002511:Cephalosporins; D005839:Gentamicins; D002435:Cefamandole; D002512:Cephalothin
Ensayo multicéntrico de frecuencia bacteriana y sensibilidad a cefamandol y otros antibióticos.