The enhancement effect of irradiation by methotrexate. Report of three complications.
Three cases are described in which complications developed which were believed to be due to the enhancement effect of irradiation by methotrexate during the course of therapy for lung, kidney, and bladder cancer. These included esophageal and large bowel complications. In two of these cases, the patients improved with conservative therapy.
D000368:Aged; D004941:Esophagitis / Q000139:chemically induced; D005260:Female; D006801:Humans; D007249:Inflammation / Q000139:chemically induced; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000494:pharmacology; D008875:Middle Aged; D009092:Mucous Membrane; D009369:Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries / Q000209:etiology*; D011838:Radiation-Sensitizing Agents
D011838:Radiation-Sensitizing Agents; D008727:Methotrexate