Cushing's syndrome associated with functional black adenoma of the adrenal cortex.
A 35-year-old woman who had bone pain in the extremities was found to have Cushing's syndrome, for which she had adrenalectomy. Pathologic examination revealed a solitary black adenoma. Bone scan and roentgenograms showed regional osteoporosis of the extremities and avascular necrosis of the hip. Her cushingoid manifestations and bone pain resolved after adrenalectomy and vitamin D therapy.
D000236:Adenoma / Q000175:diagnosis*; D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis*; D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000175:diagnosis / Q000209:etiology; D010146:Pain