title: Pressure-regulating effects of prostaglandin E2, F2 alpha and cholecystokinin on canine choledochal and pancreatic ducts in vivo.
abstract: Changes in pressure in the choledochal and pancreatic ducts of dogs brought about by PGE2 and PGF2 alpha were studied in vivo. The stimulatory action of the c8-terminal cholecystokinin was inhibited by the prostaglandin synthesis inhibitor naproxen. PGF2 alpha increased the pressure, but PGE2 caused a decrease.
mesh_terms: D000818:Animals; D002766:Cholecystokinin / Q000494:pharmacology*; D003135:Common Bile Duct / Q000187:drug effects* / Q000502:physiology; D004285:Dogs; D005260:Female; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D010183:Pancreatic Ducts / Q000187:drug effects* / Q000502:physiology; D011312:Pressure; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology*; D011461:Prostaglandins F, Synthetic / Q000494:pharmacology*
chemical_list: D011459:Prostaglandins E, Synthetic; D011461:Prostaglandins F, Synthetic; D002766:Cholecystokinin