[Importance of the diagnosis of congenital developmental defects in the practice of pathologists].
Composite studies of 1286 stillborns and infants with congenital malformations (CMF) dying at the age under 1 year conducted in the Teratological Center of Minsk showed that in specialized therapeutic institutions the causes of CMF could be established in at least 70% of the cases. In the infant autopsy materials, 12% of CMF were associated with chromosome pathology, 17% with single gene mutations, over 40% had multifactor determinants and 2.7% were due to teratogenic effects.
D000014:Abnormalities, Drug-Induced / Q000473:pathology; D000015:Abnormalities, Multiple / Q000473:pathology; D002869:Chromosome Aberrations / Q000473:pathology; D025063:Chromosome Disorders; D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
Znachenie diagnostiki vrozhdennykh porokov razvitiia v praktike patologoanatomov.