[Hyperthyroidism from placental choriocarcinoma: a case report and review of the literature (author's transl)].
The first case of placental choriocarcinoma producing clinical hyperthyroidism reported in France is described. Recovery occurred, with disappearance of the choriocarcinoma metastases and hyperthyroidism signs, after chemotherapy alone (vincristine and methotrexate). A review of the seven cases reported in the published literature showed that the hyperthyroidism could be related to the thyroid-stimulating activity of the tumoral gonadotropin (HCG).
D000328:Adult; D002822:Choriocarcinoma / Q000150:complications* / Q000188:drug therapy; D006063:Chorionic Gonadotropin / Q000378:metabolism; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000209:etiology*; D008175:Lung Neoplasms / Q000556:secondary; D008727:Methotrexate / Q000627:therapeutic use; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000150:complications* / Q000188:drug therapy; D014750:Vincristine / Q000627:therapeutic use
D006063:Chorionic Gonadotropin; D014750:Vincristine; D008727:Methotrexate
Hyperthyroïdie par choriocacinome placentaire: un cas avec revue de la littérature.