A freeze-thaw method for concentrating plasma and serum for treatment of hypogammaglobulinaemia.
Components of plasma or serum, including immunoglobulins, were concentrated two-fold by freezing then collecting 40-50% of the initial volume during thawing. This concentrated plasma (or serum) was administered intravenously to treat hypogammaglobulinaemic foals and calves. An adaptation of this method suitable for field use is described.
D000361:Agammaglobulinemia / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D001793:Blood Preservation / Q000379:methods*; D001803:Blood Transfusion; D002417:Cattle; D002418:Cattle Diseases / Q000628:therapy*; D005615:Freezing; D006168:Guinea Pigs; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D010949:Plasma