title: Long-term experiences with labetalol.
abstract: Labetalol has been used in 83 patients with severe hypertension resistant to a wide number of drugs. Adequate blood pressure control was achieved in 50 patients. Seven patients with a response in blood pressure had administration of the drug ceased because of side effects. Twenty-two of these resistant patients had little fall in blood pressure. Labetalol can be used safely in severe resistant hypertension and is indicated when a thiazide and beta-blocking drug has failed to reduce blood pressure.
mesh_terms: D000328:Adult; D000368:Aged; D004983:Ethanolamines / Q000008:administration & dosage*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007741:Labetalol / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged
chemical_list: D004983:Ethanolamines; D007741:Labetalol