Specific and potent inhibition of spermidine synthase by the transition-state analog, S-adenosyl-3-thio-1,8-diaminooctane.
D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D000478:Alkylation; D000818:Animals; D008297:Male; D011467:Prostate / Q000201:enzymology; D051381:Rats; D011436:Spermidine Synthase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D014166:Transferases / Q000037:antagonists & inhibitors*
C027548:S-adenosyl-3-thio-1,8-diaminooctane; D014166:Transferases; D011436:Spermidine Synthase; D000241:Adenosine