title: Post-encephalitic hypothalamic-pituitary insufficiency.
abstract: Pituitary function was investigated in 3 patients who developed hypothalamic-pituitary insufficiency after viral meningoencephalitis. In 2 patients the causative agents were probably Influenza-A-and Herpes simplex virus whereas in the third patient it was not identified. The pattern of hormonal deficiencies indicated that all the central regulatory areas - hypothalamus, pituitary stalk and pituitary gland - may be injured after viral meningoencephalitis. Usually, the hormonal deficiency is permanent but it can also be transient.
mesh_terms: D000328:Adult; D003919:Diabetes Insipidus / Q000209:etiology; D004671:Encephalitis, Arbovirus / Q000150:complications*; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006561:Herpes Simplex / Q000150:complications; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007018:Hypopituitarism / Q000209:etiology*; D007027:Hypothalamic Diseases / Q000209:etiology*; D007251:Influenza, Human / Q000150:complications; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008590:Meningoencephalitis / Q000150:complications*; D008875:Middle Aged; D010901:Pituitary Function Tests; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D013006:Growth Hormone; D013974:Thyroxine; D006854:Hydrocortisone