Measurement of pilocarpine and its degradation products by high-performance liquid chromatography.
An assay method for pilocarpine using reversed-phase high-performance liquid chromatography is presented. This method also measures isopilocarpine, the stereoisomer of pilocarpine, and the degradation products pilocarpic acid and isopilocarpic acid. Maximum sensitivity was obtained with optical absorbance at 216 nm.
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004355:Drug Stability; D010862:Pilocarpine / Q000032:analysis*
D010862:Pilocarpine