title: [Bromsulphalein dynamic tests in cholelithias patients before and after long-term treatment with chenodeoxycholic acid].
abstract: The BSP loading and continuous infusion tests were performed in 31 patients with cholesterol gallstones before and after long-term (6-12 months) treatment with chenodeoxycholic acid. The following parameters were evaluated: 45th minute retention percentage, plasma disappearance rate during the first 16 minutes, compartmental transfer rates, transport maximum and storage. Our results, according to previous findings after short-term treatment, indicate that no cholestatic effects seem to be induced after long-term treatment with chenodeoxycholic acid.
mesh_terms: D002635:Chenodeoxycholic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D002769:Cholelithiasis / Q000188:drug therapy*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008111:Liver Function Tests; D013448:Sulfobromophthalein / Q000378:metabolism
chemical_list: D013448:Sulfobromophthalein; D002635:Chenodeoxycholic Acid
vernacular_title: Prove dinamiche con BSF in pazienti colelitiasici prima e dopo trattamento a lungo termine con acido chenodesossicolico.