[Effects of striatum stimulation and micro-iontophoretically applied dopamine and acetylcholine on the neuronal activity of the globus pallidus].
Alert, myorelaxed rats were used to study the influence of electrical stimulation of the stiatum and micro-iontophoretic application of dopamine and acetylcholine upon the discharge activity of neurons of the Globus pallidus. Out of 55 pallidal neurons, 25 responded to striatum stimulation with an initial inhibition and subsequent irritation, and 21 with an irritation-inhibition sequence. 40% of the neurons were dopamine-sensitive (23% irritation, 77% inhibition) and 38% choline-sensitive (63% inhibition, 37% irritation). 25% of the dopamine-sensitive neurons were at the same time choline-sensitive. There was no direct relation demonstrable between the effects of striatum stimulation and micro-iontophoretic application of acetylcholine or dopamine.
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D003342:Corpus Striatum / Q000502:physiology*; D004298:Dopamine / Q000494:pharmacology*; D004558:Electric Stimulation; D005917:Globus Pallidus / Q000502:physiology*; D007478:Iontophoresis; D008297:Male; D009474:Neurons / Q000502:physiology; D051381:Rats
D000109:Acetylcholine; D004298:Dopamine
Der Einfluss von Striatumreizung und mikroiontophoretisch appliziertem Dopamin und Azetylcholin auf die neuronale Aktivität im Globus pallidus.