Effects of colchicine, cytochalasin-B and papaverine on wound healing in Xenopus early embryos.
The effects of colchicine, cytochalasin-B and papaverine on wound healing in Xenopus early embryos have been studied. Colchicine does not prevent wound healing, whereas cytochalasin-B does. Papaverine, under conditions which prevent the completion of neurulation, does not prevent wound healing. A model is given which might explain these observations.
D000818:Animals; D003078:Colchicine / Q000494:pharmacology*; D003571:Cytochalasin B / Q000494:pharmacology*; D004625:Embryo, Nonmammalian / Q000187:drug effects / Q000502:physiology*; D005260:Female; D010208:Papaverine / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects*; D014981:Xenopus
D003571:Cytochalasin B; D010208:Papaverine; D003078:Colchicine