title: The effect of cold-induced brain edema on cerebrospinal fluid formation rate.
abstract: The net contribution of vasogenic brain edema to cerebrospinal fluid (CSF) formation was studied by ventriculocisternal perfusion. Individual cats were perfused both before and 2 1/2 hours after a severe cold-induced injury to the cerebral cortex, and the results were compared. Although the edema had occupied the larger part of the hemispheric white matter and bordered the lateral ventricle, a decrease rather than an increase in CSF formation rate was observed. This decrease was related to a decrease in the cerebral perfusion pressure by a regression equation that was not affected by the cold injury.
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001834:Body Water / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D001929:Brain Edema / Q000134:cerebrospinal fluid* / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D002415:Cats; D002555:Cerebrospinal Fluid / Q000502:physiology*; D003080:Cold Temperature; D007427:Intracranial Pressure