title: A closer look at serum prostatic acid phosphatase as screening test.
abstract: Radioimmunoassay techniques for the detection of serum acid phosphatase are reported to provide substantial improvement in test sensitivity and test specificity. Calculation of the positive predictive value for this assay, however, does not support its use as a screening modality. Indiscriminate use of this test may have serious medical, psychological, and economic ramifications.
mesh_terms: D000135:Acid Phosphatase / Q000097:blood*; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D011471:Prostatic Neoplasms / Q000201:enzymology / Q000517:prevention & control*; D011863:Radioimmunoassay
chemical_list: D000135:Acid Phosphatase