A potent new salicylanilide effective against Fasciola hepatica.
In sheep, 3-tert butyl 4'5 dicyano 6 methyl 2' bromo salicylanilide was found to be active against mature Fasciola hepatica down to 0.2 mg/kg but was toxic at 1.5 mg/kg.
D000818:Animals; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use*; D005210:Fasciola hepatica; D005211:Fascioliasis / Q000188:drug therapy / Q000662:veterinary*; D051381:Rats; D012457:Salicylamides / Q000627:therapeutic use*; D012458:Salicylanilides / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*
D000980:Antiplatyhelmintic Agents; D012457:Salicylamides; D012458:Salicylanilides; C026495:3-tert-butyl-4,5'-dicyano-6-methyl-2'-bromosalicylanilide