[Lamellar formations in the brain cells of embryos of schizophrenic mothers].
Studies of the embryo brain obtained during abortions in schizophrenic mothers detected certain ultrastructural traits in the nervous tissue cellular elements. One of the most striking traits is the general increase in the surface of the intracellular membrane which appears due to the premature development of the usually present cell organellas (cytoplasmatic network, lamellar apparatus, mitochondria) and as a result of the increased proliferation of the membranes leading to formation of peculiar membrane structures--lamellasomes. The enhanced membrane proliferation gives grounds to assume that the increase in the general synthetic activity is due to the development in pathological conditions of adaptational reactions, which however are quite distinctive. The data obtained indicate a substantial distortion of cellular differentiation in the brain embryo of schizophrenic mothers.
D001921:Brain / Q000196:embryology* / Q000648:ultrastructure; D002462:Cell Membrane / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007425:Intracellular Membranes / Q000648:ultrastructure; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications; D012559:Schizophrenia / Q000235:genetics*
Lamelliarnye obrazovaniia v kletkakh golovnogo mozga émbrionov pri shizofrenii u matereĭ.