title: 2,3,7,8-Tetrachlorodibenzo-p-dioxin toxic effects and tissue levels in animals from the contaminated area of Seveso, Italy.
abstract: After the environmental contamination by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the area of Seveso, Italy, thousands of small domestic animals (mainly rabbits and poultry) died within a few weeks. Autopsies on dead animals showed various pathological signs, such as hepatic lesions and haemorrhage. TCDD was monitored in animal tissues by gas chromatography-mass fragmentography; rabbit liver levels corresponded fairly well to soil contamination, which indicated that this species can be used as a tool for tracking the presence of TCDD in the environment.
mesh_terms: D000062:Accidents, Occupational; D000818:Animals; D001717:Birds; D002415:Cats; D002417:Cattle; D002645:Chickens; D004147:Dioxins / Q000633:toxicity*; D004785:Environmental Pollutants; D006041:Goats; D006168:Guinea Pigs; D006736:Horses; D007558:Italy; D000072317:Polychlorinated Dibenzodioxins / Q000032:analysis / Q000633:toxicity*; D011817:Rabbits; D012756:Sheep; D013552:Swine
chemical_list: D004147:Dioxins; D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins