[Apolipoprotein A1, A2 and E content in the blood plasma of persons with dysalphalipoproteinemia].
The content of A1, A2, and E apolipoproteins in blood plasma of males (40-59 years of age) with normo-, hyper-, and hypoalphalipoproteinemia was determined by rocket immunoelectrophoresis. Considerable changes were revealed in the alphalipoprotein cholesterol/A1-apo ratio which were evidence of increased capacity of HDLP for transporting cholesterol in hyperalphalipoproteinemia and a decrease in this HDLP function in hypoalphalipoproteinemia irrespective of their concentration in blood plasma. A reverse correlative connection was revealed between the A1-apo content and the E-apo content in dysalphalipoproteinemia. It is suggested that the changes in the content of A1-apo and E-apo in blood plasma are significant in lipoprotein metabolism in dysalphalipoproteinemia.
D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood*; D007009:Hypolipoproteinemias / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D001053:Apolipoproteins; D008075:Lipoproteins, HDL; D014280:Triglycerides; D002784:Cholesterol
Soderzhanie apolipoproteinov A1, A2 i E v plazme krovi liudeĭ s disal'falipoproteidemieĭ.