The induction of obesity in the rat with bipiperidyl mustard.
1. Bipiperidyl mustard produced increased adiposity in the rat without excessive weight gain or hyperphagia. 2. The results suggest a metabolic aetiology for the obesity as opposed to a disorder of food intake regulation.
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D050356:Lipid Metabolism; D009150:Mustard Compounds / Q000633:toxicity*; D009765:Obesity / Q000139:chemically induced*; D051381:Rats
D009150:Mustard Compounds; C011680:bipiperidyl mustard