title: [Changes in coagulographic indices of patients with cerebral atherosclerosis complicated by mental disorders during the treatment process].
abstract: Examination and treatment of 40 patients with atherosclerotic dementia demonstrated a significant increase in some indices of the hemocoagulation system. These changes were expressed in an increase of blood tolerance to heparin, shortening of the recalcification time, increase in the fibrinogen content, presence of fibrinogen B. The group studied was characterized by the presence of slightly marked fibrinolysis compensatory reactions. Treatment by novocain combined with aspirin led to appreciable changes in these indices towards normalization, permitting to consider this form of therapy as pathogenetic.
mesh_terms: D000368:Aged; D001241:Aspirin / Q000008:administration & dosage*; D001777:Blood Coagulation; D003704:Dementia / Q000209:etiology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D001523:Mental Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D011343:Procaine / Q000008:administration & dosage*
chemical_list: D011343:Procaine; D001241:Aspirin
vernacular_title: Izmeneniia nekotorykh pokazateleĭ koagulogrammy u bol'nykh tserebral'nym aterosklerozom s psikhicheskimi narusheniiami v protsesse lecheniia.