title: [Testing of sensitivity of human tumours to cytostatics in a rapid in vitro test (author's transl)].
abstract: In a cooperative study the predictability of results of cytostatic treatment in patients with tumours using a rapid in vitro test was assessed in 9 university hospitals. Treatment of tumour patients (carcinomas of the ovary, bronchus and various localisations) was performed independently of test results. In vitro tests estimating proliferation-dependent action of cytostatics agree readily with clinical treatment results. Tumours responding badly to cytostatics in the test were also progressive clinically. Results of the rapid in vitro test may thus be used in the decision to perform or withhold cytostatic treatment.
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy; D001984:Bronchial Neoplasms / Q000188:drug therapy; D003201:Computers; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000188:drug therapy; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Sensibilitätstestung menschlicher Tumoren gegenüber Zytostatika mit einem In-vitro-Kurzzeittest. Kooperative Studie für Sensibilitätstestung von Tumoren (KSST).