[Circular dichroism study of the conformational situation in an aqueous solution of adenylyl-(3'--5')-adenosine and its conformationally mobile analogs].
The temperature dependence of CD spectra of ApA, its (2'--5')-isomer, and a number of free conformational analogues, in which the ribose ring was replaced by acyclic hydroxyalkyl substituents, has been studied. The thermodynamic parameters of conformational equilibrium were determined. The role of separate functional groups and parts of DNP molecules in the organization and stabilization of the close state as well as the role of water in the stabilization of the one stranded helix of RNA is discussed.
D000249:Adenosine Monophosphate / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D002942:Circular Dichroism; D015226:Dinucleoside Phosphates; D007536:Isomerism; D008968:Molecular Conformation; D013816:Thermodynamics
D015226:Dinucleoside Phosphates; C006412:adenylyl-(3'-5')-adenosine; D000249:Adenosine Monophosphate
Izuchenie konformatsionnoĭ situatsii v vodnom rastvore adenilil-(3'--5')-adenozina i ego konformatsionno podviznykh analogov metodom krugovogo dikhroizma.