title: Effect of immunization of male rabbits against androstenedione.
abstract: After active immunization of male rabbits against androstenedione and with increasing antibody titre the concentration of androstenedione and testosterone in peripheral blood increased more than 1000-fold resp. 20-fold above values of control animals. On histological examination of the testes a marked Leydig's cell hyperplasia was found, though there was no difference in testis weight.
mesh_terms: D000735:Androstenedione / Q000097:blood; D000736:Androstenes / Q000276:immunology*; D000818:Animals; D000906:Antibodies; D006965:Hyperplasia / Q000473:pathology; D007106:Immune Sera; D008297:Male; D011817:Rabbits; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood
chemical_list: D000736:Androstenes; D000906:Antibodies; D007106:Immune Sera; D013739:Testosterone; D000735:Androstenedione