The non-hormone chemotherapy of prostatic cancer.
Seventeen patients with hormone resistant prostatic cancer were treated with chemotherapeutic drugs. An overall response rate of 64% was obtained. In this study the toxicity rate was 29%. The problems of defining response in prostatic cancer are discussed and a protocol for the future is outlined.
D001859:Bone Neoplasms / Q000556:secondary; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D011471:Prostatic Neoplasms / Q000188:drug therapy*
D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate