[Functional state of the adrenals in lung cancer].
Catecholamines and cortisol in blood were studied in 91 lung cancer patients and in 11 patients with benign neoplasms in the lung. The investigation peformed has shown a certain dependence between the process stage and the sympatho-adrenal system functioning. Total amount of catecholamines is increased as the disease progresses, reaching the maximum at stage III and is sharply decreased at stage IV. A correlation between adrenaline and noradrenaline is changed in favour of a relative predominance of the adrenal link in the sympatho-adrenal system. The cortisol level during the malignant tumor growth is changed in an undular fashion and is mostly raised in patients with stage I and II. The development of metastases is associated with some tendency toward raising catecholamines level and lowering the functional activity of the adrenal cortex.
D000305:Adrenal Cortex Hormones / Q000097:blood; D000311:Adrenal Glands / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000503:physiopathology; D008175:Lung Neoplasms / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D013564:Sympathetic Nervous System / Q000503:physiopathology
D000305:Adrenal Cortex Hormones
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