Neuropharmacologic evaluation in spinal cord injury patients using membrane catheter cystosphincterometry.
Synchronous cystosphincterometry with a membrane catheter was done on spinal cord injury patients. Bladder and urethral pressures were monitored quantitatively during vesical filling and emptying. Phentolamine, propantheline and bethanechol chloride were administered to selected patients with bladder and urethral dysfunction. The membrane catheter technique was an excellent method to evaluate the pharmacology of detrusor and urethral function.
D001626:Bethanechol Compounds / Q000627:therapeutic use; D002404:Catheterization; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D010646:Phentolamine / Q000627:therapeutic use; D011312:Pressure; D011413:Propantheline / Q000627:therapeutic use; D013119:Spinal Cord Injuries / Q000150:complications*; D014521:Urethra / Q000187:drug effects* / Q000503:physiopathology*; D001743:Urinary Bladder / Q000187:drug effects* / Q000503:physiopathology; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*
D001626:Bethanechol Compounds; D011413:Propantheline; D010646:Phentolamine