The role of a noxious taste in determining food intake in the rat.
Adult female rats were given access to cornstarch, fat, and 2 cups of casein ad lib. Sucrose octaacetate was added to one or both casein cups in concentrations of 0, 0.1, or 2.5%. The lower concentrations of SOA had no effect on total caloric intake or food choices, although a taste aversion experiment indicated that the rats could detect SOA at this level. The 2.5% concentration had no effect on total caloric intake. If only one casein cup was treated with SOA, the animals consumed 70% of their protein from the unadulterated casein supply, but total protein intake was unchanged. If both cups were treated with 2.5% SOA, protein intake decreased, but carbohydrate consumption showed a compensatory increase. Fat intake was unchanged.
D000085:Acetates / Q000494:pharmacology; D000818:Animals; D004032:Diet / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004435:Eating; D002149:Energy Intake / Q000187:drug effects*; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D005503:Food Additives / Q000494:pharmacology*; D005518:Food Preferences / Q000187:drug effects*; D051381:Rats; D013395:Sucrose / Q000494:pharmacology; D013649:Taste / Q000502:physiology*
D000085:Acetates; D005503:Food Additives; D013395:Sucrose