A South African family with antithrombin III deficiency.
Antithrombin III is the most important natural inhibitor of coagulation. Reduced levels of antithrombin III are a well-documented cause of hypercoagulability. Several families have been described with hereditary antithrombin III deficiency, including one from South Africa. We report a second South African family with this defect.
D000990:Antithrombin III / Q000097:blood; D020152:Antithrombin III Deficiency; D001778:Blood Coagulation Disorders / Q000453:epidemiology / Q000235:genetics*; D001780:Blood Coagulation Tests; D002648:Child; D006801:Humans; D008297:Male; D010375:Pedigree; D013019:South Africa
D000990:Antithrombin III