Endogenous dissemination of genital Herpesvirus hominis type 2 to the eye.
A 33-year-old man developed Herpesvirus hominis type 2 (HVH-2) eye disease following a herpetic lesion of the penis. The sequence of ocular involvement suggested that the virus had been transmitted endogenously from the genital lesion: granulomatous iritis was followed by interstitial keratitis and then by dendritic keratitis. Recurrent bacterial ulcers ultimately required a conjunctival flap. The course of this man's ocular disease as well as those of other reported cases of HVH-2 adult eye infections appeared to be more severe and prolonged than that of the average patient with ocular herpes type 1 infection.
D000328:Adult; D006561:Herpes Simplex; D006801:Humans; D007635:Keratitis, Dendritic / Q000209:etiology*; D008297:Male; D010409:Penile Diseases / Q000150:complications*; D014605:Uveitis / Q000209:etiology