Proline synthesis from glutamate in the mitochondria isolated from a blowfly, Aldrichina grahami.
Proline biosynthesis from glutamate was demonstrated in a cell free system prepared from blowfly abdomen. The biosynthetic activity was found mainly in the mitochondrial fraction. The biosynthesis of proline from glutamate required ATP, NADPH and Mg++ as cofactors.
D000818:Animals; D005971:Glutamates / Q000378:metabolism*; D007313:Insecta / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism*; D011392:Proline / Q000096:biosynthesis*; D013347:Subcellular Fractions / Q000378:metabolism
D005971:Glutamates; D011392:Proline