Afibrinogenemia and blunt head injury.
A case is described of acute defibrination following blunt head injury in a patient with a Spitz-Holter drain. The cause of the disseminated intravascular coagulation is thought to be due to brain thromboplastins entering the systemic circulation through the Spitz-Holter drain, thus bypassing the blood-brain barrier.
D000063:Accidents, Traffic; D000293:Adolescent; D000347:Afibrinogenemia / Q000209:etiology*; D001930:Brain Injuries / Q000150:complications* / Q000378:metabolism; D002557:Cerebrospinal Fluid Shunts; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D005260:Female; D006801:Humans; D013925:Thromboplastin / Q000378:metabolism; D014949:Wounds, Nonpenetrating / Q000150:complications*
D013925:Thromboplastin