Haemoglobin J Rovigo 53 alpha (E-2) aspartic acid alanin.
The case under examination is an example of a family with Hb J Rovigo interacting with beta thalassemia. Such hemoglobin has the same mobility as J haemoglobin, and the analysis of amino acids showed it to be a variant of the alpha 53 (E2) Alanine-Aspartic chain. The percentage of haemoglobin ranged from around 22.7 to 30.5%.
D004588:Electrophoresis, Cellulose Acetate; D004906:Erythrocyte Count; D005260:Female; D006443:Hemoglobin A2 / Q000032:analysis; D006448:Hemoglobin J / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D008297:Male; D013789:Thalassemia / Q000097:blood / Q000235:genetics*
D006455:Hemoglobins, Abnormal; D006448:Hemoglobin J; D006443:Hemoglobin A2