title: Persistence of impaired heat tolerance from artificially induced miliaria rubra.
abstract: Ten volunteers were heat acclimatized to 48.9 degrees C (Ta), 20% rh for 7 days to complete a 100-min walk on a level treadmill (1.56 m x s-1). Subjects were then divided into experimental (n = 6) and control (n = 4) groups. Miliaria rubra (heat rash) was then induced on the experimental subjects by wrapping them for 3 days in polyethylene plastic. All six developed marked miliaria with involvement of 40-70% of the total body surface area. All subjects were reexposed to walking in the heat on the 7th day after unwrapping, by which time rash was clinically indetectable, and again 14 days after unwrapping. On the first test (day 7) only one of the rashed group, and on the second test (day 14) only two could complete the 100-min walk; the control group finished without difficulty on both days. Body heat storage for the rash group was 2.5 times that of the control group on day 7 and 1.5 as great on day 14; measurements of mean body temperature (Tb) on the rash group indicated a much greater heat stress when compared to their own prerash-acclimatized values or those of the control group. These data demonstrate the potential of "healed" miliaria in the etiology of clinical heat illness.
mesh_terms: D000064:Acclimatization; D000328:Adult; D001833:Body Temperature Regulation; D006339:Heart Rate; D006358:Hot Temperature; D006801:Humans; D007007:Hypohidrosis / Q000209:etiology; D008297:Male; D008883:Miliaria / Q000503:physiopathology*; D005082:Physical Exertion; D013545:Sweat Glands / Q000503:physiopathology*; D013997:Time Factors