[Concordance of clinical signs of schizophrenia in families with hereditary loading].
A study of the clinical concordancy in 410 schizophrenic patients (sibs and parents -- children) detected the most frequent coinciding traits of the disease in the sibs and parent -- children pairs. The following traits were attributed to the coinciding features: premorbid schizoid personality traits, a short initial period, a pseudopsychopath syndrome in the initial period, paranoid manifest symptomatology, paranoid form of schizophrenia, a continuous progressive development of the process, apathico-abulic defect symptomatology. It was demonstrated that the variance of traits in the clinical picture of schizophrenia in hereditary loaded families is subjected to the impact of such factors as sex, age, supplementary hereditary loading by psychoses, exogenous factors.
D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D012075:Remission, Spontaneous; D012559:Schizophrenia / Q000235:genetics*; D012560:Schizophrenia, Catatonic / Q000235:genetics; D012562:Schizophrenia, Disorganized / Q000235:genetics; D012563:Schizophrenia, Paranoid / Q000235:genetics; D012737:Sex Factors; D013577:Syndrome
Konkordantnost' klinicheskikh proiavleniĭ shizofrenii v nasledstvenno otiagoshchennykh sem'iakh.