title: Surface and cytoplasmic antigens in retinoblastoma.
abstract: Surface and cytoplasmic antigens in retinoblastoma were examined by antisera prepared against two tissue-cultured retinoblastoma cell lines. In addition, several other antisera, including anti-rhodopsin, anti-rod outer segment, anti-large-molecular-weight protein, anti-S, and anti-P antigen, were also utilized in a complement-dependent cytotoxicity assay in order to explore the tumor cell surface. Antisera to tissue-cultured retinoblastoma cell lines were cross-reactive to both cell lines as was rod outer segment antiserum.
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D002478:Cells, Cultured; D003429:Cross Reactions; D003593:Cytoplasm / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D005134:Eye Neoplasms / Q000276:immunology*; D006801:Humans; D012175:Retinoblastoma / Q000276:immunology*; D012374:Rod Cell Outer Segment / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm; D000954:Antigens, Surface