Long term stability of lysine vasopressin and of specifically tritiated lysine vasopressin in weakly acidic aqueous solutions.
Lysine vasopressin tritiated at meta position of tyrosine (1.9 Ci/mmole) decomposes during a long storage period, mainly as a result of radiolysis. The loss of specific activity by isotopic exchange with water is slow. The nonlabelled peptide undergoes only very minute decomposition (polymerization). Specific radioactivity declines with a half life of 47.4 months.
D000818:Animals; D001681:Biological Assay; D001794:Blood Pressure / Q000187:drug effects; D004355:Drug Stability; D007553:Isotope Labeling; D007700:Kinetics; D008236:Lypressin / Q000494:pharmacology; D008433:Mathematics; D013997:Time Factors; D014316:Tritium
D014316:Tritium; D008236:Lypressin