Behavioural effects in rats following repeated exposure to methyl bromide.
Rats were exposed to methyl bromide (MB) at concentrations of 200 ppm and 300 ppm, 4 h per day, 5 times weekly, for 3 weeks. After the final exposure, behavioural tests for emotional response equilibrium function, the function of the peripheral nerve and the circadian rhythm of spontaneous activity were performed. Relatively prolonged dysfunction of the peripheral nerve as well as disturbance of the circadian rhythm of spontaneous activity were observed.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D002940:Circadian Rhythm / Q000187:drug effects; D004644:Emotions / Q000187:drug effects; D006842:Hydrocarbons, Brominated / Q000633:toxicity*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D010525:Peripheral Nerves / Q000187:drug effects; D004856:Postural Balance / Q000187:drug effects; D051381:Rats
D006842:Hydrocarbons, Brominated; C005218:methyl bromide