title: Multiple atrial dysrhythmias in a horse.
abstract: A variety of atrial dysrhythmias including paroxysmal atrial tachycardia, atrial tachycardia with 2nd-grade atrioventricular block, atrial fibrillation, and atrial flutter developed in a 5-year-old Quarter Horse gelding. Quinidine and propranolol were not successful in restoring normal sinus rhythm. Sinus rhythm was re-established during digoxin therapy, but later reverted to atrial dysrhythmia. At necropsy, multiple, discrete pale areas were found on both atria and the interatrial myocardium. Histologic examination of these lesions demonstrated myocytolysis and replacement by fibrous connective tissue.
mesh_terms: D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D004077:Digoxin / Q000627:therapeutic use; D004562:Electrocardiography / Q000662:veterinary; D006325:Heart Atria / Q000473:pathology / Q000503:physiopathology*; D006734:Horse Diseases / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D006736:Horses; D008297:Male; D013610:Tachycardia / Q000503:physiopathology / Q000662:veterinary
chemical_list: D004077:Digoxin