title: [Various features of the morphology, clinical picture and treatment of oligodendrogliomas of the cerebral hemispheres].
abstract: The morphological and clinical peculiarities, the findings of auxiliary examination methods, and the results of surgical and combined treatment of oligodendrogliomas of the cerebral hemispheres in 122 patients are discussed. The growth of oligodendrogliomas from the subependymal zone in two directions, into the cavity of the cerebral ventricles or extraventricular, is their morphological peculiarity. The authors show 12 variants of the localization of the tumor. The criteria for the diagnosis of oligodendroglioma are diffuse headache at the onset of the disease not of a hypertensive character; the prevalence of focal symptoms of irritation at the onset of the disease and of general cerebral symptoms over focal symptoms in the stage of decompensation; frequent epileptic seizures in the structure of which generalized attacks predominate in the early stages of the disease; rare occurrence of alduminosis in the cerebrospinal fluid; calcifications seen on the craniogram and relatively rare appearance of craniographic signs of hypertension. The most effective method of treatment in most cases is a radical operation with excision of the initial growth zone; combination of operation with chemotherapy applied during the operation and in the postoperative period is indicated in dedifferentiated oligodendrogliomas.
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002551:Cerebral Ventricle Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009837:Oligodendroglioma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D013687:Telencephalon
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Nekotorye osobennosti morfologii, kliniki i lecheniia oligodendrogliom bol'shikh polushariĭ golovbogo mozga.