Presence of Herpesvirus ovis DNA sequences in cellular DNA from sheep lungs affected with jaagsiekte (pulmonary adenomatosis).
To investigate further the possible involvement of Herpesvirus ovis in the aetiology of jaagsiekte, the kinetics of reassociation of viral DNA and DNA isolated from tumour tissue as well as from cell cultures derived from it were studied. Although DNA-DNA hybridization could be demonstrated in 2 cases of jaagsiekte, no correlation was found between the presence of Herpesvirus ovis genome sequences and the occurrence of the disease.
D000818:Animals; D001483:Base Sequence; D004279:DNA, Viral / Q000032:analysis*; D006564:Herpesviridae / Q000032:analysis*; D007700:Kinetics; D008168:Lung / Q000032:analysis; D011648:Pulmonary Adenomatosis, Ovine / Q000209:etiology / Q000378:metabolism*; D012756:Sheep; D014158:Transcription, Genetic
D004279:DNA, Viral