title: Nonivasive detection of retrograde descending aortic flow in infants using continuous wave doppler ultrasonography. Implications for diagnosis of aortic run-off lesions.
abstract: Continuous wave Doppler ultrasonography was utilized to detect and characterize descending aortic blood flow velocity patterns in 27 preterm and term infants with or without an aortic run-off lesion proximal to the descending aorta. The effects of coexistent intracardiac defects on the velocity time profiles were evaluated by comparing records from patients with no intracardiac defects or systemic run-off lesions to those with a variety of intracardiac defects but no systemic run-off lesion. No significant alterations were noted. In all patients, the velocity tracing in systole was triangular in shape. During diastole, however, there were qualitative and quantitative differences between patients with and without a proximal run-off lesion. In those without a run-off lesion, retrograde descending aortic flow was present only in early diastole, and aortic flow velocity oscillated around the zero baseline during mid and late diastole. In those with a run-off lesion, retrograde flow present in early diastole continued throughout diastole. Quantitatively, the ratio of the area under the retrograde flow portion of the tracing to the forward flow portion was significantly greater in those with a run-off lesion. The velocity time profiles obtained with CW Doppler were similar to those previously obtained invasively with electromagnetic flow probes of catheter-mounted velocitometers. CW Doppler ultrasonograpy provides a reliable, noninvasive method for describing descending aortic blood flow velocity in infants.
mesh_terms: D001013:Aorta, Thoracic / Q000503:physiopathology*; D001775:Blood Circulation; D001783:Blood Flow Velocity; D004374:Ductus Arteriosus, Patent / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D014463:Ultrasonography