Retinal lesions in Alport's syndrome.
We described a family in which two siblings were suffering from Alport's syndrome. Both had identical ocular lesions: whitish-grey dots in the superficial layers of the retina mainly in the posterior pole. The visual acuity, the visual field, and the fundus fluorescein angiogram were normal. These lesions were associated with an impaired ERG. The ocular finding seems to be characteristic of the Alport's syndrome.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004596:Electroretinography; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009394:Nephritis, Hereditary / Q000150:complications*; D012160:Retina / Q000473:pathology; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*