[Effect of colchamine on the mitotic activity of leukemic cells of mouse spleen].
Significant suppression of the entry of leukemic spleen cells in mitosis was found to be produced by the administration of colchamin (5 mg/kg) to mice with transplanted leukemia La. These data allow a conclusion that the duration of mitosis and the rate of mitotic activity in tissues cannot be determined by the colchamin method.
D000818:Animals; D000970:Antineoplastic Agents; D003703:Demecolcine / Q000494:pharmacology* / Q000627:therapeutic use; D007942:Leukemia, Experimental / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D008938:Mitosis / Q000187:drug effects*; D009368:Neoplasm Transplantation; D013154:Spleen / Q000473:pathology*; D014184:Transplantation, Homologous
D000970:Antineoplastic Agents; D003703:Demecolcine
Vliianie kolkhamina na mitoticheskuiu aktivnost' leĭkoznykh kletok selezenki myshi.