title: [R amplitude changes and ST segment lowering in the exercise ECG compared with angiographic findings (author's transl)].
abstract: The results of exercise ECG and coronary angiography in 73 patients (20 without, 53 with significant coronary stenoses) were compared in a retrospective study. A sensitivity of 47%, 58% and 60% and a specificity of 90%, 90% and 65% was found in the 3 criteria used, i.e. ST lowering, R amplitude change and pectanginous symptoms. Combination of ST lowering and (or) R amplitude change showed a higher sensitivity by 11% and a better specificity by 15% when compared to ST lowering and (or) angina pectoris. Taking all 3 criteria of ischaemia into account (occurring singly or in combination) sensitivity increased to 91%, however, specificity decreased to 55%. The high accuracy of R amplitude change is caused by recognition of patients with diminished exercise tolerance (low pressure-frequency product). Patients with positive R amplitude changes do not differ from those with decreasing R amplitude as regards left ventricular enddiastolic pressure and ejection fraction during rest.
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
vernacular_title: R-Amplituden-Veränderung und ST-Strecken-Senkung im Belastungs-EKG im Vergleich mit angiographischen Befunden.