Sodium nitroprusside-induced hypotension in radical thoraco-abdominal dissection of retroperitoneal lymph nodes.
Blood loss and replacement in 57 consecutive otherwise healthy young patients undergoing radical thoraco-abdominal dissection of retroperitoneal lymph nodes is reviewed. Twenty-five patients received nitroprusside (hypotensive group); 32 patients (normotensive group) did not. Blood loss varied significantly between the hypotensive and normotensive groups: the mean loss (+/- SEM) was 920 +/- 72 ml for the hypotensive group compared with 1341 +/- 98 ml for the normotensive group (P < 0.001). The total blood requirement for the normotensive patients was three times that of the hypotensive group. The difference between the two groups was more apparent in patients with advanced disease.
D000328:Adult; D001803:Blood Transfusion; D005292:Ferricyanides; D006400:Hematocrit; D006470:Hemorrhage; D006801:Humans; D007023:Hypotension, Controlled; D007431:Intraoperative Complications; D008197:Lymph Node Excision / Q000379:methods; D008297:Male; D009599:Nitroprusside; D012187:Retroperitoneal Space; D013736:Testicular Neoplasms / Q000473:pathology
D005292:Ferricyanides; D009599:Nitroprusside