Tolerance to the Mydriatic effects of morphine in mice.
When injected to mice, opiates produce mydriasis. Animals treated chronically with morphine, developed tolerance to the mydriatic effects of morphine. The degree and consistency of the response make the pupil a valuable tool in opiate research.
D000818:Animals; D004361:Drug Tolerance; D008297:Male; D051379:Mice; D009020:Morphine / Q000494:pharmacology*; D009184:Mydriatics / Q000494:pharmacology*; D011680:Pupil / Q000187:drug effects*; D013997:Time Factors
D009184:Mydriatics; D009020:Morphine