title: Tolerance to the Mydriatic effects of morphine in mice.
abstract: When injected to mice, opiates produce mydriasis. Animals treated chronically with morphine, developed tolerance to the mydriatic effects of morphine. The degree and consistency of the response make the pupil a valuable tool in opiate research.
mesh_terms: D000818:Animals; D004361:Drug Tolerance; D008297:Male; D051379:Mice; D009020:Morphine / Q000494:pharmacology*; D009184:Mydriatics / Q000494:pharmacology*; D011680:Pupil / Q000187:drug effects*; D013997:Time Factors
chemical_list: D009184:Mydriatics; D009020:Morphine