Treatment of ureteral and biliary pain with an injectable salt of indomethacin.
A study was carried out to investigate the analgesic effect of an injectable salt of indomethacin - methylglucamine indomethacinate - in patients with acute ureteral and biliary pain. Out of 106 consecutive patients treated by the intramuscular (average dose 72.6 mg) or intravenous (average dose 36.1 mg) route, 76 (71.6%) had complete relief of pain and 4 were remarkably improved. In 68.8% of the cases, complete relief was reached within 1 hour from the start of treatment. No important side-effects were observed. Headache, nausea and drowsiness were reported in a few cases.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001660:Biliary Tract Diseases / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D014515:Ureteral Diseases / Q000188:drug therapy*
D007213:Indomethacin