title: Coronary ostial stenosis following aortic valve replacement without continuous coronary perfusion.
abstract: The development of coronary ostial stenosis following aortic valve replacement has been attributed to intraoperative trauma to the coronary vessels during continuous coronary perfusion. We describe two patients with this lesion in whom continuous coronary perfusion was not used during aortic valve replacement. Both patients were successfully treated with saphenous vein bypass grafting. Intraoperative observation of the aortic root at the time of the bypass operation in one case revealed the left coronary ostium to be pinpoint in size and involved in a dense fibrous reaction extending up from the sewing ring of the prosthesis. The findings in these cases support the hypothesis that coronary ostial stenosis following aortic valve replacement may be due to a fibrous reaction in the aortic root secondary to turbulent flow through the aortic prosthesis.
mesh_terms: D001024:Aortic Valve Stenosis / Q000601:surgery*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000209:etiology*; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*