Clinical chemistry determinations for a biracial cohort of 1,605 normal and hyperlipidemic schoolchildren aged 6 to 17.
Distributions of nine clinical chemistry determinations (serum bilirubin, globulin, creatinine, thyroxine, alkaline phosphatase, hematocrit, aspartate aminotransferase, uric acid, and plasma glucose) were assessed for 1,605 schoolchildren aged 6 to 17 years, in the Cincinati Lipid Research Clinic's Princeton School District study. Nine hundred and sixteen children were randomly recalled, and 689 were recalled by virtue of elevated (top decile) plasma cholesterol or triglyceride or both. For each clinical chemistry measurement, the following factors were considered: random and hyperlipidemic recall groups, age, sex, and race. The data were arrayed to provide the fifth percentile, the median, and the ninety-fifth percentile levels, as well as the 90% confidence interval of about the fifth and ninety-fifth percentile estimates. These data allow black-white age and sex, and normal-hyperlipidemic comparisons of commonly measured clinical chemistry determinations among a large population of children. This study also provides, for the methods used, accurate estimations of age-, sex-, race-, and recall group-specific percentile distributions for selected clinical chemistry determinations for children.
D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D006400:Hematocrit; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000201:enzymology; D008297:Male; D044469:Racial Groups; D012712:Serum Globulins / Q000032:analysis; D013974:Thyroxine / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D012712:Serum Globulins; D014527:Uric Acid; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D013974:Thyroxine; D001663:Bilirubin