title: [Factors responsible for the persistence of rabies virus in cell cultures].
abstract: Persistence of rabies virus (RV) was studied in two cell cultures: HEp-2-RV and BHK-RV. The infection was demonstrated in 8% cells of the BHK-RV system and 53% cells of HEp-2-RV system by the method of cloning. The virus-free clones were as sensitive to RV infection as the control cultures. The incubation temperature shifts up to 40 degrees C and down to 34 degrees C did not affect the carrier state. 5-BUDR did not activate the infectious process in the chronically infected cells. The factors possibly responsible for RV persistence in cell cultures are discussed.
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell; D002460:Cell Line; D006224:Cricetinae; D066298:In Vitro Techniques; D007668:Kidney; D007822:Laryngeal Neoplasms; D011820:Rabies virus / Q000254:growth & development*; D014779:Virus Replication
vernacular_title: Faktory, otvetstvennye za persistentsiiu virusa beshenstva v kletochnykh kul'turakh.