title: An epizootic of measles in captive silvered leaf-monkeys (Presbytis cristatus) in Malaysia.
abstract: An epizootic of measles occurred in a group of 31 silvered leaf-monkeys (Presbytis cristatus) that had been in captivity for 4-12 months. Twenty-four of the monkeys exhibited a maculopapular rash that persisted for 6-9 days. A serous to mucopurulent nasal discharge and conjunctivitis were seen in some animals. Eight monkeys died during the epizootic; however, their deaths could not be directly attributed to measles. Serum samples from the surviving monkeys collected 1-2 months prior to, and 5 weeks after, the epizootic were examined by the complement-fixation and hemagglutination-inhibition tests for antibodies to measles virus. The preepizootic complement-fixation titers were all less than 1:4 and hemagglutination-inhibition titers, less than 1:10. The postepizootic complement-fixation titers in 21 of 23 surviving monkeys ranged from 1:8 to 1:128, and hemagglutination-inhibition titers in 22 of 23 monkeys ranged from 1:40 to 1:80 or greater.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D000914:Antibodies, Viral / Q000032:analysis; D002520:Cercopithecidae; D003168:Complement Fixation Tests; D004196:Disease Outbreaks / Q000662:veterinary*; D006385:Hemagglutination Inhibition Tests; D008296:Malaysia; D008457:Measles / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D008459:Measles virus / Q000276:immunology; D008992:Monkey Diseases / Q000453:epidemiology* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral