Urinary primaquine excretion and red cell methaemoglobin levels in man following a primaquine:chloroquine regimen.
1 Red cell methaemoglobin levels were found to be significantly raised in healthy subjects given a 14-day course of primaquine with chloroquine on the first 3 days. 2 The methaemoglobin levels were not related to the quantity of primaquine excreted. 3 No primaquine could be detected in the plasma at 24 h following the last three daily doses.
D002738:Chloroquine / Q000097:blood; D004359:Drug Therapy, Combination; D004912:Erythrocytes / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008706:Methemoglobin / Q000032:analysis*; D011319:Primaquine / Q000097:blood / Q000652:urine*
D002738:Chloroquine; D008706:Methemoglobin; D011319:Primaquine