The appearance of mania following intravenous calcium replacement.
The appearance of mania in a 35-year-old woman following the rapid intravenous correction of hypocalcemia is described. The importance of physiological fluctuations of serum calcium in affective modulation is stressed. Caution in speed of replacement of deficiency states is recommended.
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000139:chemically induced*; D001714:Bipolar Disorder / Q000139:chemically induced*; D002125:Calcium Gluconate / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005942:Gluconates / Q000009:adverse effects*; D006801:Humans; D006996:Hypocalcemia / Q000523:psychology; D007263:Infusions, Parenteral; D008274:Magnesium / Q000097:blood / Q000627:therapeutic use; D019965:Neurocognitive Disorders / Q000188:drug therapy
D005942:Gluconates; D008274:Magnesium; D002125:Calcium Gluconate