Hereditary angioneurotic oedema.
HAE is transmitted by an autosomal dominant gene. It is due to a defect in the complement system and should be distinguished from the other two types of angio-oedema, i.e. allergic and idiopathic types. Pathogenesis and treatment are discussed and two new cases of HAE have been reported here. I would stress here two points: first, that the family should be investigated for the possibility of HAE; secondly, that the patient should carry a medical card similar to those carried by haemophilic patients, containing the diagnosis, name of the G.P. and emergency treatment.
D000328:Adult; D000402:Airway Obstruction / Q000517:prevention & control; D000799:Angioedema / Q000188:drug therapy / Q000235:genetics* / Q000276:immunology; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D003174:Complement C1 Inactivator Proteins / Q000097:blood; D003613:Danazol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000933:Antifibrinolytic Agents; D003174:Complement C1 Inactivator Proteins; D003613:Danazol