title: The effect of trichloroethylene on some serum-enzymes, on the cytoenzymological activity in leucocytes, and on the acid-base equilibrium.
abstract: Twenty male volunteers were exposed to 95 ppm trichloroethylene for 4 h. Immediately before and aftere xposure and 4 h and 20 h after cessation, some serum-enzymes, the cytoenzymological activity of the alkaline and acid phosphatases and the naphthol-AS-D-esterase in neutrophil granulocytes and the acid-base equilibrium were investigated. Compared with the control experiment, the activities of the three neutrophil enzymes increased during trichloroethylene exposure with high significance. No significant changes of the serum-enzymes and the acid-base equilibrium could be found.
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000293:Adolescent; D000328:Adult; D004798:Enzymes / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D013997:Time Factors; D014238:Trichloroacetic Acid / Q000097:blood; D014241:Trichloroethylene / Q000633:toxicity*
chemical_list: D004798:Enzymes; D014241:Trichloroethylene; D014238:Trichloroacetic Acid