The structure of lienomycin, a pentaene macrolide antitumor antibiotic. II. The location of the pentaene chromophore and of six isolated double bonds. The complete structure of the antibiotic.
The locations of the isolated double bonds and of the pentaene chromophore in lienomycin (I) were established by chemical degradation of I followed by MS and 1H NMR examination of the products. The complete structure of the antibiotic is proposed.
D000903:Antibiotics, Antineoplastic; D055598:Chemical Phenomena; D002621:Chemistry; D013058:Mass Spectrometry; D008968:Molecular Conformation; D011090:Polyenes
D000903:Antibiotics, Antineoplastic; D011090:Polyenes; C008279:lienomycin