Non-sterile intermittent catheterization with antibiotic prophylaxis in the acute spinal cord injured male patient.
The efficacy of antibiotic prophylaxis by the oral and intravesical routes was studied in acute spinal cord injury patients maintained on a non-sterile intermittent catheterization program. There were 25 male patients investigated and monitored with daily urine cultures. Significant bacteriuria occurred at a rate of 0.83 per cent. This infection rate was greater than that determined previously using a sterile catheterization technique (0.28 per cent), p less than 0.05). Control patients catheterized with a sterile technique and no antibiotic prophylaxis had an infection rate of 0.96 per cent. Establishment of significant bacteriuria was more prominent when patients were catheterized every 8 hours as opposed to every 4 hours. Despite antibiotic prophylaxis the non-sterile procedure results in unacceptable rates of significant bacteriuria. The sterile technique may be preferred in the acute spinal cord center.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001437:Bacteriuria / Q000517:prevention & control; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D013119:Spinal Cord Injuries / Q000150:complications*; D013242:Sterilization; D013997:Time Factors; D014546:Urinary Catheterization / Q000379:methods*
D000900:Anti-Bacterial Agents