Showdomycin and its reactive moiety, maleimide. A comparison in selective toxicity and mechanism of action in vitro.
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D001692:Biological Transport / Q000187:drug effects; D002460:Cell Line; D003545:Cysteine / Q000494:pharmacology; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism; D008297:Male; D008301:Maleimides / Q000494:pharmacology*; D051379:Mice; D009705:Nucleosides / Q000378:metabolism; D012787:Showdomycin / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D008301:Maleimides; D009705:Nucleosides; D012787:Showdomycin; D000241:Adenosine; D003545:Cysteine