Reye syndrome in Ohio, 1973-1977.
Some major epidemiologic features of Reye syndrome have been elucidated since the first description of this clinical entity. Multiple studies have shown an association with epidemic influenza B and endemic varicella. Little population data are available on age, sex, race, geographic distribution, and secular trends. A five-year retrospective population-based study of 190 Ohio residents diagnosed with Reye syndrome from January 1, 1973-December 31, 1977, is reported here. The temporal relationships between the occurrence of Reye syndrome and influenza B and varicella were confirmed; however, a high number of blacks and city dwellers with Reye syndrome were found in this study.
D000293:Adolescent; D000367:Age Factors; D002644:Chickenpox / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D007251:Influenza, Human / Q000150:complications*; D008297:Male; D009820:Ohio; D012189:Retrospective Studies; D012202:Reye Syndrome / Q000453:epidemiology* / Q000209:etiology; D012959:Socioeconomic Factors; D014504:Urban Health