title: [Aggressive fibromatosis].
abstract: On the basis of examinations made in 16 patients, morphological and clinical aspects as well as aetiology and therapy of desmoid tumours are discussed. For the first time human lymphocyte antigens (HLA) were determined, pointing to a genetic predisposition. Guide-lines for the surgical management are established. Hormonal, cytostatic and irradiation therapy are evaluated.
mesh_terms: D000328:Adult; D004198:Disease Susceptibility; D005260:Female; D005350:Fibroma / Q000209:etiology* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D012739:Gonadal Steroid Hormones; D006680:HLA Antigens; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000293:injuries; D009364:Neoplasm Recurrence, Local
chemical_list: D012739:Gonadal Steroid Hormones; D006680:HLA Antigens
vernacular_title: Aggressive Fibromatose.