title: Controlled ultrafiltration during single-pass dialysis with the RP-6 dialyzer and evaluation of its time-dependent ultrafiltration index.
abstract: A simple and inexpensive method is described for controlling ultrafiltration when using the high flux RP-6 dialyzer. When th RP-6 is operated in the co-current mode and with single-pass dialysate delivery, (PBo-PDo) can be used to accurately and safely control ultrafiltration. Combined results from ten dialyses indicate there is a pressure-dependent concentration polarization which affects ultra-filtration as reported previously, and in addition, a time-dependent effect indicating a more complex dialyzer/blood interaction. The ultrafiltration index decreases linearly with time. The ultrafiltration can be adequately predicted by (Formula: see text).
mesh_terms: D001783:Blood Flow Velocity; D005069:Evaluation Studies as Topic; D006801:Humans; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D011312:Pressure; D006435:Renal Dialysis / Q000379:methods*; D012996:Solutions; D013997:Time Factors; D014160:Transducers, Pressure; D014462:Ultrafiltration / Q000379:methods*
chemical_list: D008567:Membranes, Artificial; D012996:Solutions