title: Caprine toxoplasmosis: abortion, clinical signs, and distribution of Toxoplasma in tissues of goats fed Toxoplasma gondii oocysts.
abstract: Thirteen goats (9 does and 4 bucks) were each inoculated orally with 10,000 infective Toxoplasma gondii oocysts. Three does and one buck were used as noninoculated controls. In 2 to 4 days after inoculation (DAI), inoculated goats became dull, pyrectic (40 to 41 C), and anorectic. Three goats died (10, 10, and 14 DAI) and two goats were killed (7 and 32 DAI) because they were moribund; also, 3 does aborted, 2 had weak kids, and 2 had dead fetuses. Toxoplasma was isolated from the placenta of three goats, and the fetal tissues of four goats. The control goats remained asymptomatic. The distribution of T gondii in blood and other tissues was studied by inoculation of mice with caprine tissues. Parasitemia was detected in 7 of 7 goats--beginning 4 DAI in 1 goat, 5 DAI in 5 goats, and 8 DAI in 1 goat. The parasitemia lasted 3 to 10 days. Toxoplasma was isolated from the milk of 2 goats at 12 and 14 DAI. Toxoplasma was isolated from 15 or more tissues of 5 goats killed 7 to 35 DAI and from 10 tissues of 2 goats killed 69 and 95 DAI.
mesh_terms: D000034:Abortion, Veterinary / Q000469:parasitology*; D000818:Animals; D005260:Female; D005333:Fetus / Q000469:parasitology; D005334:Fever / Q000662:veterinary; D006041:Goats; D006321:Heart / Q000469:parasitology; D008297:Male; D008892:Milk / Q000469:parasitology; D010920:Placenta / Q000469:parasitology; D011247:Pregnancy; D014124:Toxoplasmosis, Animal / Q000469:parasitology*