Corticosteroids and malnutrition. Aspergillus lung abscess in an asthmatic child.
An adolescent developed invasive pulmonary aspergillosis in the limited form of a lung abscess. She had a weak immunologic response to the infection. Her depressed immunity was the result of prolonged corticosteroid therapy, compounded by malnutrition. In spite of this and other complications of corticosteroids, she made a full recovery from the fungal infection following treatment with amphotericin B and surgical excision of the lung abscess.
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000361:Agammaglobulinemia / Q000209:etiology; D001228:Aspergillosis / Q000209:etiology* / Q000276:immunology; D001249:Asthma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008169:Lung Abscess / Q000209:etiology* / Q000276:immunology; D009748:Nutrition Disorders / Q000150:complications*
D000305:Adrenal Cortex Hormones