Stereospecific nicotine receptors on rat brain membranes.
A stereospecific binding site for nicotine has been detected on rat brain membranes. Competition studies with cholinergic agonists suggest that this site is a nicotinic cholinergic receptor.
D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000378:metabolism*; D008024:Ligands; D008297:Male; D009538:Nicotine / Q000378:metabolism; D051381:Rats; D011950:Receptors, Cholinergic / Q000378:metabolism*; D011978:Receptors, Nicotinic / Q000378:metabolism*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013570:Synaptic Membranes / Q000378:metabolism
D008024:Ligands; D011950:Receptors, Cholinergic; D011978:Receptors, Nicotinic; D009538:Nicotine