Dendritic abnormalities in patients with subacute sclerosing panencephalitis (SSPE). A Golgi study.
Golgi studies of three cortical biopsies from patients with SSPE reveal an abnormal pyramidal dendritic domain, spine-loss, and reactive gliosis. These findings support results obtained in a previous ultrastructural study of this disease, and are in keeping with the pathological features observed in other situations in which mental changes occur.
D000293:Adolescent; D001706:Biopsy; D002540:Cerebral Cortex / Q000473:pathology; D002648:Child; D003712:Dendrites; D005911:Gliosis / Q000473:pathology; D006801:Humans; D008297:Male; D013344:Subacute Sclerosing Panencephalitis / Q000473:pathology*