title: Analysis of some two-locus systems for traits exhibiting continuous variation.
abstract: Some generalized two-locus, major-gene models for traits exhibiting continuous expression are investigated. Conditions of gametic equilibria are stated as functions of the parameters characterizing the within phenotypic-genotypic distributions. Selection is stabilizing in favor of an optimum phenotype. It is established that an increase in the phenotypic variance facilitates stability of a central polymorphic state with tighter linkage. Also, with increased phenotypic variance in an additive two-locus selection model, a HARDY-WEINBERG type of equilibrium will be less central. The rate of convergence, in this case, is slowed down with an augmented environmental background.
mesh_terms: D008040:Genetic Linkage; D014644:Genetic Variation; D005838:Genotype; D008433:Mathematics; D008957:Models, Genetic; D010641:Phenotype; D011110:Polymorphism, Genetic; D012641:Selection, Genetic