title: Non-sterile intermittent catheterization with antibiotic prophylaxis in the acute spinal cord injured male patient.
abstract: The efficacy of antibiotic prophylaxis by the oral and intravesical routes was studied in acute spinal cord injury patients maintained on a non-sterile intermittent catheterization program. There were 25 male patients investigated and monitored with daily urine cultures. Significant bacteriuria occurred at a rate of 0.83 per cent. This infection rate was greater than that determined previously using a sterile catheterization technique (0.28 per cent), p less than 0.05). Control patients catheterized with a sterile technique and no antibiotic prophylaxis had an infection rate of 0.96 per cent. Establishment of significant bacteriuria was more prominent when patients were catheterized every 8 hours as opposed to every 4 hours. Despite antibiotic prophylaxis the non-sterile procedure results in unacceptable rates of significant bacteriuria. The sterile technique may be preferred in the acute spinal cord center.
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001437:Bacteriuria / Q000517:prevention & control; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D013119:Spinal Cord Injuries / Q000150:complications*; D013242:Sterilization; D013997:Time Factors; D014546:Urinary Catheterization / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents