Sarcoidosis associated with combined immunodeficiency.
The association of multiple non-caseating granulomata and a positive Kviem test is normally considered to be indicative of a diagnosis of sarcoidosis. However, although depressed cell-mediated immunity is commonly described, it is extremely rare to find a humoral immune paresis. A patient is reported who had multiple granulomata, depressed cellular and humoral immunity and a positive Kveim test.
D000328:Adult; D000917:Antibody Formation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000503:physiopathology; D007731:Kveim Test; D012507:Sarcoidosis / Q000150:complications*; D013154:Spleen / Q000601:surgery