Systemic sarcoidosis and electrocardiographic conduction abnormalities. Electrophysiologic evaluation of two patients.
Two patients with long histories of sarcoidosis had progression of conduction abnormalities to heart block and severe bradycardia. Conduction system involvement was trifascicular in both patients, though evidence for left ventricular functional impairment was otherwise lacking. Sudden death is seen more commonly in patients with sarcoidosis who have diffuse myocardial involvement, while conduction abnormalities can occur with relatively localized disease.
D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000209:etiology; D004562:Electrocardiography; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications / Q000503:physiopathology*