title: Congenital bilateral horizontal gaze palsy in a brother and sister.
abstract: A man of 21 years and his sister aged 20 years had congenital bilateral horizontal gaze palsy. Convergence was normal but the vestibulocephalic and oculocephalic reflexes were absent. Aplasia of the paramedian zone of the pontine tegmentum, on a familial basis, is postulated as the cause.
mesh_terms: D000328:Adult; D005133:Eye Movements; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D008297:Male; D009886:Ophthalmoplegia / Q000151:congenital* / Q000503:physiopathology; D011149:Pons / Q000002:abnormalities*