Effect of nitrilotriacetic acid (NTA) on the distribution of manganese-54 in rats.
The effect of single dose of NTA on the removal of radio-manganese in various organs and in plasma has been studied in rats which received single i.v. injection of 54Mn(II). The lowered value of radio-manganese in NTA treated rats as compared to control animal indicates that NTA binds rapidly and forms stable and diffusible complex resulting in the fast excretion of the injected 54Mn(II).
D000085:Acetates / Q000494:pharmacology*; D000818:Animals; D002614:Chelating Agents / Q000494:pharmacology; D008297:Male; D008345:Manganese / Q000378:metabolism*; D009571:Nitrilotriacetic Acid / Q000494:pharmacology*; D011868:Radioisotopes; D051381:Rats; D014018:Tissue Distribution
D000085:Acetates; D002614:Chelating Agents; D011868:Radioisotopes; D008345:Manganese; D009571:Nitrilotriacetic Acid