title: Malate dehydrogenase isozymes in the longnose dace, Rhinichthys cataractae.
abstract: The interspecies homology of dace supernatant (A2,AB,B2) and mitochondrial (C2) malate dehydrogenase isozymes has been established through cell fractionation and tissue distribution studies. Isolated supernatant malate dehydrogenase (s-MDH) isozymes show significant differences in Michaelis constants for oxaloacetate and in pH optima. Shifts in s-MDH isozyme pH optima with temperature may result in immediate compensation for increase in ectotherm body pH with decrease in temperature, but duplicate s-MDH isozymes are probably maintained through selection for tissue specific regulation of metabolism.
mesh_terms: D000818:Animals; D002451:Cell Compartmentation; D004592:Electrophoresis, Starch Gel; D005399:Fishes / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D008291:Malate Dehydrogenase / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D007527:Isoenzymes; D008291:Malate Dehydrogenase