[Biosynthesis of rat spleen DNA following stimulation of hematopoiesis with phenylhydrazine].
3H-Thymidine incorporation into DNA of rat spleen was increased 11-fold, as compared with controls, within the fourth day of the experiment involving two daily administrations of phenylhydrazine. HCl into the animals at a dose of 3 mg/100 g of body mass. Administration of 1 mCi of 3H-thymidine per 100 g of body mass enabled to obtain 3H-DHA from rat spleen with specific radioactivity of 30-40 x 10(6) imp/min per 1 mg of the biopolymer.
D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D006410:Hematopoiesis / Q000187:drug effects*; D010659:Phenylhydrazines / Q000494:pharmacology*; D051381:Rats; D013154:Spleen / Q000378:metabolism*; D013936:Thymidine / Q000378:metabolism
D010659:Phenylhydrazines; D004247:DNA; D013936:Thymidine
Biosintez DNK selezenki krys posle stimuliatsii krovetvoreniia fenilgidrazinom.