Pulmonary arterial structure in pulmonary atresia after prostaglandin E2 administration.
Administration of long-term, oral prostaglandin E2 in two babies with pulmonary atresia did not appear to influence pulmonary arterial smooth muscle development, nor was there evidence of damage to the vessel walls, as has previously been reported after treatment of the same condition with prostaglandin E1.
D000284:Administration, Oral; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D011458:Prostaglandins E / Q000008:administration & dosage / Q000627:therapeutic use*; D011651:Pulmonary Artery / Q000187:drug effects* / Q000473:pathology
D011458:Prostaglandins E