[Photoelectronic recording of Evan's Blue influx into the blood vessels of tumors with selectively evoked hemostasis as compared to healthy tissue. Retardation of dye influx as a criterion of microcirculation inhibition (author's transl)].
The method of relative microcirculation measurement using Evan's Blue was further improved and results on applying this method to tumors treated with the Cancer Multistep Therapy (CMT) are reported. The microcirculation of these tumors decreased irreversibly below 1% of the value of healthy tissue. The strong, selective inhibition of microcirculation corresponds practically to the separation of the tumor from the organism. Recorded curves demonstrate that this strong inhibition can be achieved neither by hyperthermia nor by hyperglycemia alone, but only by combination of these both steps.
D000818:Animals; D002296:Carcinosarcoma / Q000098:blood supply* / Q000628:therapy; D005070:Evans Blue; D006487:Hemostasis; D006943:Hyperglycemia; D006979:Hyperthermia, Induced; D008297:Male; D008833:Microcirculation; D009132:Muscles / Q000098:blood supply; D051381:Rats
D005070:Evans Blue
Vergleichende photoelektronische Registrierung des Einstromes von Evansblau in das Blutgefässsystem von Normalgewebe und von Tumoren mit selektiv ausgelöster Hämostase. Verlangsamung des Farbeinstromes als Gradmesser der Mikrozirkulationshemmung.