Behavioral predictors of amitriptyline response in depression.
In this study of 18 female depressed patients and 18 age- and sex-matched control subjects, the authors examined the relationship between nonverbal behavior and treatment outcome with amitriptyline. A behavioral analysis indicated that amitriptyline responders could be differentiated from nonresponders before drug treatment on the basis of discrete nonverbal behaviors. Nonresponders showed a high frequency of body-focused self-adaptors, posture shifts, and pauses and a low frequency of smiles, while responders displayed long speech pauses and long durations of head aversion.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000639:Amitriptyline / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009633:Nonverbal Communication; D012917:Social Adjustment; D014705:Verbal Behavior / Q000187:drug effects
D000639:Amitriptyline