Direct demonstration of the formation of prostaglandin E2 due to phosphatidylinositol breakdown associated with stimulation of enzyme secretion in the pancreas.
D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism; D002108:Ceruletide / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D007700:Kinetics; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism*; D010712:Phosphatidic Acids / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism; D011458:Prostaglandins E / Q000096:biosynthesis*
D001095:Arachidonic Acids; D010712:Phosphatidic Acids; D010716:Phosphatidylinositols; D010743:Phospholipids; D011458:Prostaglandins E; D002108:Ceruletide