The 24-hour pattern of serum TSH in patients with endogenous depression.
The 24-h pattern of serum thyrotropin (TSH) has been studied using hourly blood-sampling in four patients with severe endogenous depression. All patients showed a pattern similar to that of normal subjects, with lowest levels of serum TSH between 0900 and 2000 h and highest levels between 2100 and 0800 h. A phaseshift of the TSH rhythm can therefore not account for our previous finding of a significant negative correlation between severity of endogenous depression and night increase in serum TSH measured as the difference between the values at 2400 and 1400 h.
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000097:blood; D002940:Circadian Rhythm; D003866:Depressive Disorder / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011187:Posture; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine