[Effectiveness and duration of action of nifedipine in effort angina (author's transl)].
The anti-anginal activity of nifedipine was studied after a dosage of 10 and 20 mg in nine patients suffering from a typical, stable effort angina pectoris. The effectiveness and the duration of action of nifedipine was evaluated by serial cycloergometer exercise testing repeated after the administration of the two dosage of nifedipine, for six hours. Nifedipine significantly increased exercise tolerance before angina pectoris, with an action lasting at least two hours after 10 mg and six hours after 20 mg. We also evaluated the changing of hemodynamic parameters (heart rate, blood pressure, double product) before and after the drug in the same day.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy*; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*
D011725:Pyridines; D009543:Nifedipine
Efficacia e durata d'azione della nifedipina nell'angor da sforzo. Somministrazione acuta.