Effect of Trichinella spiralis infection on the experimental amebic liver abscess in hamsters.
The development of experimental amebic liver abscess in hamsters was inhibited by a previous infection with the nematode parasite Trichinella spiralis, such that liver abscesses were present in 26% of hamsters with T. spiralis infection and in 80% of T. spiralis-free controls. The protective effect of T. spiralis infection is believed to be exerted through a non-specific activation of cellular immunity, with macrophages as probable effector cells.
D000818:Animals; D006224:Cricetinae; D007111:Immunity, Cellular; D007114:Immunization; D008101:Liver Abscess, Amebic / Q000150:complications / Q000276:immunology* / Q000517:prevention & control; D008264:Macrophages / Q000276:immunology; D008647:Mesocricetus; D014235:Trichinellosis / Q000150:complications / Q000276:immunology*