[Acylase activity of groups of actinomycetes and bacteria].
The acylase activity of 113 actinomycetous strains and 71 bacterial strains was studied. A number of strains producing acylases, hydrolyzing phenoxymethylpenicillin was detected among the actinomycetous cultures and a number of strains producing acylases active against ampicillin and benzylpenicillin was detected among the bacterial cultures. These acylases may be used in production of semisynthetic beta-lactam antibiotics and their semiproducts.
D000192:Actinomycetales / Q000201:enzymology*; D000581:Amidohydrolases / Q000096:biosynthesis*; D001419:Bacteria / Q000201:enzymology*; D004789:Enzyme Activation; D004790:Enzyme Induction; D006868:Hydrolysis; D010406:Penicillins / Q000378:metabolism; D013379:Substrate Specificity
D010406:Penicillins; D000581:Amidohydrolases; C019665:amidase
Atsilaznaia aktivnost' nekotorykh grupp aktinomitsetov i bakteriĭ.