Phenytoin-induced teratogenesis: a mouse model.
Malformations associated with the fetal hydantoin syndrome have been reproduced in a mouse model. The occurrence of these defects was correlated with maternal serum concentrations, but not with maternal or fetal genotype or the presence of a seizure disorder.
D000818:Animals; D004195:Disease Models, Animal; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology; D010672:Phenytoin / Q000009:adverse effects*; D013723:Teratogens
D013723:Teratogens; D010672:Phenytoin