Sister chromatid exchange and chromosome aberrations in lymphocytes of laboratory personnel.
The genotoxic risk caused by environmental chemicals may be detected by analyzing the frequency of sister chromatid exchanges in peripheral blood lymphocytes. Up to now the frequency of sister chromatid exchange has been correlated with smoking habits, and it is also observed to be significantly higher in lymphocytes of laboratory personnel.
D002869:Chromosome Aberrations; D003434:Crossing Over, Genetic / Q000187:drug effects*; D005027:Ethylene Oxide / Q000633:toxicity; D006801:Humans; D007753:Laboratories; D008214:Lymphocytes / Q000648:ultrastructure*; D009369:Neoplasms / Q000188:drug therapy; D009784:Occupational Diseases / Q000235:genetics*; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D012907:Smoking
D005027:Ethylene Oxide