Preparation of the vagina for surgery. A comparison of povidone-iodine and saline solution.
Patients undergoing major vaginal surgery and treated with prophylactic antibiotics were assigned to two groups in which the effectiveness of preoperative vaginal preparation with povidone-iodine was compared with that of saline solution. There was no difference in postoperative morbidity between the two groups, although a few more infections occurred in the group treated with povidone-iodine. It is suggested that simple dilution of the quantity of bacteria in the vagina is all that is essential for adequate preoperative vaginal preparation.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007045:Hysterectomy, Vaginal; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage*; D011300:Preoperative Care / Q000379:methods*; D012965:Sodium Chloride / Q000008:administration & dosage*; D013530:Surgical Wound Infection / Q000517:prevention & control; D007507:Therapeutic Irrigation; D014621:Vagina / Q000382:microbiology / Q000601:surgery*
D000900:Anti-Bacterial Agents; D012965:Sodium Chloride; D011206:Povidone-Iodine; D011205:Povidone