title: Experimental transmission of Treponema hyodysenteriae from mice to pigs.
abstract: Transmission experiments with Treponema hyodysenteriae were conducted with mice and pigs, using laboratory mice as the carrier host. Mice were intragastrically inoculated with T hyodysenteriae and placed in a contact with nonexposed mice or healthy pigs. Contact mice mingled with infected mice at 5 or 180 days after inoculation were shedding T hyodysenteriae in their feces 9 to 14 days after exposure. Pigs exposed directly to infected mouse feces were shedding T hyodysenteriae in their feces after 5 to 17 days of exposure and developed swine dysentery after 11 to 13 days. Transmission of T hyodysenteriae to pigs through direct contact with feces from infected mice indicates that rodents in the field may be a reservoir host and may also be involved in spreading swine dysentery.
mesh_terms: D000818:Animals; D005243:Feces / Q000382:microbiology; D005260:Female; D051379:Mice; D012376:Rodent Diseases / Q000382:microbiology / Q000635:transmission*; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology / Q000635:transmission*; D014208:Treponema / Q000302:isolation & purification; D014211:Treponemal Infections / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*