[Scanning electron microscopic study of the effect of some intraocular irrigating solutions on the corneal endothelium].
The effects of two intraocular irrigating solutions (physiological saline, Mac Carey-Kaufman medium) on the corneal endothelium of the rabbit have been evaluated by scanning electron microscopy. During an experimental anterior vitrectomy on aphakic rabbit eyes, corneas were perfused with a different solution in each eye during a period of up to 75 min and with a maximum of 250 cm3 of liquid. We found a significant difference only after 60 min of perfusion at which time important lesions appeared in the cornea of eyes perfused with physiological saline. The corneas irrigated with Mac Carey-Kaufman medium remained normal.
D000818:Animals; D003315:Cornea / Q000187:drug effects* / Q000648:ultrastructure; D003316:Corneal Diseases / Q000139:chemically induced*; D004727:Endothelium / Q000187:drug effects / Q000648:ultrastructure; D008854:Microscopy, Electron; D009883:Ophthalmic Solutions / Q000009:adverse effects / Q000494:pharmacology*; D011817:Rabbits; D012965:Sodium Chloride / Q000009:adverse effects; D007507:Therapeutic Irrigation; D013997:Time Factors
D009883:Ophthalmic Solutions; D012965:Sodium Chloride
Etude comparée en microscopie électronique à balayage de l'action de diverses solutions oculaires d'irrigation sur l'endothélium cornéen.