Clotting competence of intracavitary blood in trauma victims.
In order to assess more rationally the requirement for anticoagulation during intraoperative autotransfusion, the clotting competence of blood collected from the body cavities of 31 trauma victims entering our emergency department with indications for intraoperative transfusion was assessed. Blood was collected at thoracotomy or laparotomy prior to the institution of any anticoagulant measures and was assessed for clotting competence, the presence of fibrinogen, the presence of soluble fibrin monomere, and the appearance of fibrin degradation products. The prothrombin time, partial thromboplastin time, and thrombin time of this blood were markedly elevated; fibrinogen was absent; soluble fibrin monomer was absent; and fibrin degradation products were markedly elevated. Blood collected from body cavities is then incoagulable, and we suggest that in the autotransfusion of such a product the need for anticoagulation may be reduced.
D000007:Abdominal Injuries / Q000097:blood*; D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000032:analysis; D001780:Blood Coagulation Tests; D001804:Blood Transfusion, Autologous; D006465:Hemoperitoneum / Q000097:blood*; D006491:Hemothorax / Q000097:blood*; D006801:Humans; D007430:Intraoperative Care; D013898:Thoracic Injuries / Q000097:blood*
D001779:Blood Coagulation Factors