Oxantel-pyrantel pamoate for the treatment of soil-transmitted helminths.
A mixture of oxantel-pyrantel pamoate was given to 147 primary school children. A single daily dose of 15 mg per kg body weight was administered to cases with Ascaris lumbricoides and Trichuris trichiura infections. The same single daily dose was given for three consecutive days to 10 cases with hookworm infections. The cure rate was 93.7% for ascariasis and the egg reduction rate was 98.2%. A cure rate and an egg reduction rate for trichuriasis was 70.2% and 86.5% respectively. All cases with hookworm infection were cured. Side effects were light and did not cause any anxiety.
D000293:Adolescent; D001196:Ascariasis / Q000188:drug therapy*; D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D007214:Indonesia; D009332:Necatoriasis / Q000188:drug therapy*; D010270:Parasite Egg Count; D011715:Pyrantel / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011716:Pyrantel Pamoate / Q000627:therapeutic use*; D014257:Trichuriasis / Q000188:drug therapy*
D011715:Pyrantel; D011716:Pyrantel Pamoate; C003407:oxantel