title: Experimental infection of goats and guinea pigs with Microsporum canis and trials on treatment with canesten cream and neguvon solution.
abstract: Goats and guinea pigs were found to be quite susceptible to infection with the bovine strain of Microsporum canis. The severe and characteristic annular lesions seen in goats suggested the suitability of this species as a model for future research. The lesions in both goats and guinea pigs are described in details. Trials on treatment of the experimentally induced lesions with 1% canesten cream and 6% neguvon solution were attempted. The efficacy of the drugs used were assessed on the basis of clinical observation., Wood's lamp, direct microscopy, culture and histopathology. Canesten cream produced quick and remarkable results which advocates its use in a widescale in veterinary practice.
mesh_terms: D000818:Animals; D003022:Clotrimazole / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006041:Goats; D006168:Guinea Pigs; D007093:Imidazoles / Q000627:therapeutic use*; D008297:Male; D012376:Rodent Diseases / Q000188:drug therapy*; D012867:Skin / Q000473:pathology; D014236:Trichlorfon / Q000627:therapeutic use*
chemical_list: D007093:Imidazoles; D014236:Trichlorfon; D003022:Clotrimazole