DNA replication, repair, and repair tests.
The rate of inhibition and recovery of DNA synthesis can be used in a rapid assay system to detect genotoxic potentials of chemicals. Also, the observation that an agent stimulates DNA repair in a test system indicates its ability to cause damage in DNA. Different experimental approaches to the study of repair synthesis are discussed.
D000818:Animals; D004260:DNA Repair; D004261:DNA Replication / Q000187:drug effects; D006882:Hydroxyapatites / Q000633:toxicity; D007962:Leukocytes / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism
D006882:Hydroxyapatites; D013936:Thymidine