Membrane conductance and action potential of a regenerating axonal tip.
The electrical membrane properties of axotomized and regenerating giant axons from the nerve cord of the cockroach Periplaneta americana were studied. Immediately after axotomy there was a decrease in resting potential, input resistance, and action potential amplitude near the cut end. This decrease was followed by the disappearance of the sodium-dependent action potential; an increase in the resting membrane conductance to K+, Na+, and Ca2+; and the appearance of a calcium-dependent action potential.
D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000502:physiology*; D002118:Calcium / Q000502:physiology; D004553:Electric Conductivity; D008564:Membrane Potentials; D009416:Nerve Regeneration; D010526:Periplaneta; D012964:Sodium / Q000502:physiology; D013997:Time Factors
D012964:Sodium; D002118:Calcium