title: The anthelmintic activity and toxicity of 2,2-dichlorovinyl dimethyl phosphate (dichlorvos) in equines.
abstract: Dichlorvos in a special slow release formulation at 31 mg/kg body mass in equines was highly effective against all adult strongyles and Oxyuris equi, Parascaris equorum, Probstmayria vivipara and bots of Gasterophilus spp. It has no effect on 4th stage larvae of Trichonema ssp. nor the stomach worms Draschia megastoma and Habronema spp. Doses of dichlorovos 10 and 20 times the therapeutic dose (310 and 620 mg/kg body mass) caused transient clinical signs but these disappeared 96 hours after dosing.
mesh_terms: D000818:Animals; D000871:Anthelmintics; D001200:Ascaris; D004006:Dichlorvos / Q000008:administration & dosage* / Q000494:pharmacology / Q000633:toxicity; D005243:Feces / Q000469:parasitology; D006376:Helminths; D006736:Horses / Q000469:parasitology*; D010124:Oxyuroidea; D010270:Parasite Egg Count / Q000662:veterinary; D013321:Strongyloides
chemical_list: D000871:Anthelmintics; D004006:Dichlorvos