[Antimicrobial activity of various hydrazones containing benzofuran and 1H-indene units].
A few hydrazones holding benzofuran and 1H-indene moieties were synthesized and screened for in vitro antimicrobial activity. The most active N'-(5-nitro-2-furoyl)-N2-(3-chloro-1H-indenyl-2-methylene)hydrazine (II c) showed higher activity than nitrofurantoin against some microorganisms, especially Pseudomonas aeruginosa.
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology; D006835:Hydrazones / Q000138:chemical synthesis* / Q000494:pharmacology; D007192:Indenes / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D001572:Benzofurans; D006835:Hydrazones; D007192:Indenes
Attività antimicrobica di alcuni idrazoni contenenti unità benzofuranica e 1H-indenica.