Characterization of a new antibiotic of iturin group: bacillomycin D.
The characterization of an antibiotic isolated from a strain of Bacillus subtilis revealed that this compound is a new antifungal antibiotic of the iturin group. It contains a lipid moiety which is a mixture of 3-amino 12-methyl tridecanoic acid (40%) and 3-amino 12-methyl tetradecanoic acid (60%) and a peptide moiety: L-Asp1, D-Asp1, L-Glu1, L-Pro1, D-Ser1, L-Thr1 and D-Tyr1. These two moieties are joined by a threonyl-beta-aminoacid linkage.
D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000302:isolation & purification; D023181:Antimicrobial Cationic Peptides; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006868:Hydrolysis; D010455:Peptides; D010456:Peptides, Cyclic / Q000032:analysis / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides; D010455:Peptides; D010456:Peptides, Cyclic; C027845:bacillomycin D