Non-neural influences in the determination of chick skeletal muscle.
The technique of chicken-quail hybridization in "in vitro" cultures was used. Muscle differentiation of 9 H.H. chick embryo somites without the participation of nerve fibres was noted when they were cultured in the presence of quail pectoral muscle cells. It is suggested that this non-neural model may also be valid "in vivo", and that it probably interacts with the neurodependent mechanism demonstrated in a previous paper.
D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo / Q000166:cytology*; D004627:Embryonic Induction; D006822:Hybrid Cells / Q000166:cytology; D008648:Mesoderm / Q000166:cytology; D008857:Microscopy, Interference; D009132:Muscles / Q000166:cytology / Q000196:embryology*; D009412:Nerve Fibers / Q000502:physiology; D011784:Quail