title: [Effect on lipidemia in the rat of bis-homoanalogs of adenine nucleosides].
abstract: The hypolipidemic activity of a series of adenine nucleosides bis-homoanalogues was evaluated in the rat and compared with that of the sodium salt of erythadenine, used as reference standard. Some compounds were more effective in lowering serum cholesterol than erythadenine, but all showed a reduced effect on serum triglyceride content.
mesh_terms: D000227:Adenine Nucleotides / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D002784:Cholesterol / Q000097:blood; D000960:Hypolipidemic Agents / Q000138:chemical synthesis*; D008055:Lipids / Q000097:blood; D051381:Rats; D014280:Triglycerides / Q000097:blood
chemical_list: D000227:Adenine Nucleotides; D001647:Bile Acids and Salts; D000960:Hypolipidemic Agents; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Azioni sulla lipidemia del ratto di bis-omoanaloghi di nucleosidi dell'adenina.