title: Chromosomal aberrations in bone marrow of Chinese hamsters exposed to styrene and ethanol.
abstract: No significant increase was detected in the number of chromosomally damaged cells in bone marrow of Chinese hamsters after either inhalation exposure to 300 ppm styrene or oral intake of 15% ethanol in drinking water (exposure time 4 days or 3 weeks). In combined exposure, a slight increase of chromosomal aberrations was observed in the group exposed for 4 days (2.0% aberrant cells vs. 0.0% in controls). The group exposed for 3 weeks to combined treatment showed no response (0.3% aberrant cells vs. 0.7% in controls).
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002869:Chromosome Aberrations / Q000187:drug effects*; D006224:Cricetinae; D003412:Cricetulus; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D013343:Styrenes / Q000494:pharmacology*
chemical_list: D013343:Styrenes; D000431:Ethanol