title: [Anatomo-pathological study of the development of a focus of cryonecrosis in the rat spleen].
abstract: A focus of cryonecrosis in the rat spleen, induced with liquid nitrogen (4 mm diameter probe, application time 2') does not cause haemorrhage either during or after treatment. The frozen area, which is of infarctual type with disappearance of spleen cells and preservation of the elastic structures of the follicular arteries, sees its surface reduced considerably and is replaced by connective tissue within 30 days.
mesh_terms: D000818:Animals; D003080:Cold Temperature / Q000009:adverse effects; D007238:Infarction / Q000150:complications; D009336:Necrosis; D009584:Nitrogen / Q000009:adverse effects*; D051381:Rats; D013158:Splenic Diseases
chemical_list: D009584:Nitrogen
vernacular_title: Studio anatomo-patologico dell'evoluzione di un focolaio di crionecrosi nella milza di ratto.