[Comparative characteristics of the experimental antifibrillatory action of anti-arrhythmia preparations].
Effect of lidocain, quinidine, ethmozine, cordaron and obsidan on the ventricular fibrillation threshold was studied in experiments on cats with an opened thorax under nembutal anesthesia. The experiments were carried out on normal animals and animals with acute myocardial infarction exposed to isadrin. Lidocain exerted the most pronounced antifibrillar action in all 3 series of experiments. Ethmozine was most active in animals exposed to isadrin.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D002415:Cats; D004353:Drug Evaluation, Preclinical; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000187:drug effects; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy; D014693:Ventricular Fibrillation / Q000188:drug therapy
D000889:Anti-Arrhythmia Agents
Sravnitel'naia kharakteristika protivofibrilliatornogo deĭstviia nekotorykh protivoaritmicheskikh preparatov v éksperimente.