Estradiol and progersterone receptors in F1 (C3H X RIII) mice mammary tumors: effect of castration.
The estradiol binding capacity has been determined in the cytosol of spontaneous mammary cancer in the high-mammary-tumor F1 (C3H X RIII) hybrid mice. This binding is modified neither during tumor growth nor after ovariectomy. Since these tumors do not regress after ovariectomy, they are classified as ovarian-independent for their growth, although their estradiol binding capacity is maintained, at its low initial level.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism*; D051379:Mice; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D004958:Estradiol