title: Histopathological changes after pseudophakos.
abstract: Cataract extraction and iris clip lens implantation in an 88-year-old woman were followed by hyphaema, anterior uveitis and organised exudates around the implant. The globe was enucleated after 15 months due to pain and a poor visual prognosis. Sections showed an epithelial downgrowth into part of the anterior chamber, associated with a fibrous membrane which had surrounded part of one loop of the implant. Atrophy of the iris, adenomatous changes in a ciliary process and an after-cataractous ring were noted. Inflammatory changes were present in the uvea, associated posteriorly with degenerative choroido-retinitis, probably of arteriosclerotic origin. The nylon loops of the implant showed areas of biodegradation and were partly fibrosed in. The possible relationship of the various changes is discussed.
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D001673:Biodegradation, Environmental; D004848:Epithelium / Q000473:pathology; D005128:Eye Diseases / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007910:Lenses, Intraocular / Q000009:adverse effects*; D009757:Nylons / Q000009:adverse effects; D014605:Uveitis / Q000209:etiology
chemical_list: D009757:Nylons