title: [Primary evaluation of the cytogenetic activity and potential mutagenic hazard of 22 pesticides].
abstract: The paper deals with the primary principle of potential mutagenic pesticides hazard evaluation from the results of study on their cytogenetic activity in experimental animals. This evaluation may be based on two main parameters characterizing a mutagenic property of pesticides--the degree of maximum cytogenetic effect expression and the level of minimum effective dose. According to the suggested principle 22 pesticides under study are distributed into some groups in conformity with the degree of their potential mutagenic hazard.
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008677:Metaphase / Q000187:drug effects; D051379:Mice; D009153:Mutagens; D010575:Pesticides / Q000494:pharmacology*
chemical_list: D009153:Mutagens; D010575:Pesticides
vernacular_title: Pervichnaia otsenka tsitogeneticheskoĭ aktovnosti i potentsial'noĭ mutagennoĭ opasnosti 22 pestitsidov.