title: [Gamma teletherapy of inoperable retroperitoneal tumors with nonuniform distribution of the dosage in the tissues].
abstract: The clinical material is used to substantiate the advantage of the technic of uneven irradiation of patients with primary locally spread tumors of the retroperitoneal space, in whom all the routinely used methods of treatment proved to be infective. Uneven distribution of the dosage is provided by using a grid diaphragm and conducting gamma-therapy only from one static field during the whole course of irradiation. This pattern of radiotherapy is shown to increase radioresistance of normal tissues and allows 1.5--4 times large focal dose to be applied to tumor compared with gamma-therapy via moving lead strips, thus rendering an enhanced antitumor effect of radiation. These data are confirmed by the results of clinical observations over 30 patients with locally spread inoperable tumors of the retroperitoneal space.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage; D012186:Retroperitoneal Neoplasms / Q000401:mortality / Q000532:radiotherapy*
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Distantsionnaia gamma-terapiia neoperabel'nykh opukholeĭ zabriushinnogo prostranstva v usloviiakh neravnomernogo raspredeleniia dozy v tkaniakh.