Chromosomal analysis of couples with repeated spontaneous abortions.
Chromosome banding studies were carried out on both partners of 182 consecutive couples with a history of two or more spontaneous abortions. Seventeen abnormal karyotypes were detected. This represents a frequency of 4.67 per cent, which is higher than hitherto reported. The pregnancy outcome in 105 couples with normal and abnormal karyotype was compared and no significant difference was found.
D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D007446:Chromosome Inversion; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D014178:Translocation, Genetic