title: [Reactivity of patients under lithium-therapy/assessment of multivariate relationships (author's transl)].
abstract: A representative sample of patients under long-term lithium therapy was examined with respect to performance in reaction task, mood, and attitude toward lithium therapy. Reaction time to simple acoustic or visual stimuli as well as reactivity in complex settings under power- and speed-conditions requiring psychomotoric response represent the bulk of the data. Significant effects of additional medication, sex and duration of lithium therapy are assessed by univariate and multivariate data analysis. A hierarchic cluster analysis results in 5 well interpretable clusters. The clusters, furthermore, demonstrate the importance of attitude and other psychological variable, e.g. morning-/evening-type.
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001290:Attitude; D002940:Circadian Rhythm; D004644:Emotions / Q000187:drug effects; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy; D008606:Mental Processes / Q000187:drug effects; D008875:Middle Aged; D010775:Photic Stimulation; D011581:Psychological Tests; D011930:Reaction Time / Q000187:drug effects*; D012737:Sex Factors
chemical_list: D008094:Lithium
vernacular_title: Multivariate Zusammenhänge im Leistungsverhalten von Lithium-Patienten.