Possible cell surface receptor for Friend murine leukemia virus isolated with viral envelope glycoprotein complexes.
Water-soluble multimeric complexes of Friend leukemia virus envelope glycoprotein gp85 bind specifically to C57BL/6 mouse spleen leukocytes. Such complexes were used to isolate cell surface receptors for the virus, using an immunoprecipitation technique. The putative rceptor has a molecular weight of 14,000. Mouse H-2 histocompatibility antigens, which are receptors for Semliki Forest virus, are not receptors for Friend leukemia virus.
D000818:Animals; D005622:Friend murine leukemia virus / Q000502:physiology*; D006023:Glycoproteins; D007962:Leukocytes / Q000648:ultrastructure*; D051379:Mice; D008970:Molecular Weight; D011991:Receptors, Virus / Q000302:isolation & purification*; D013154:Spleen / Q000648:ultrastructure; D014764:Viral Proteins
D006023:Glycoproteins; D011991:Receptors, Virus; D014764:Viral Proteins