title: Effects of antibiotics on platelet functions in human plasma in vitro and dog plasma in vivo.
abstract: The effects of 31 antibiotics on platelet aggregation in human plasma in the presence of adenosine 5'-diphosphate were studied. The marked activity of tetracycline hydrochloride led to a study of its effects on various platelet functions in vivo in dogs.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects; D004285:Dogs; D006801:Humans; D066298:In Vitro Techniques; D010974:Platelet Aggregation / Q000187:drug effects*; D013752:Tetracycline / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D013752:Tetracycline