title: Elastosis perforans serpiginosa.
abstract: Elastosis perforans serpiginosa (EPS) is a cutaneous connective tissue disorder featuring transepidermal elimination of altered elastic tissue. Morphologically and histologically EPS presents characteristic patterns; the case reported herein classically illustrates these patterns. In approximately one-fourth of reported cases, EPS has been associated with systemic connective tissue disorders and may thus be a useful clue in the early recognition of diseases such as Down's syndrome or pseudoxanthoma elasticum.
mesh_terms: D000293:Adolescent; D003240:Connective Tissue Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*