Low incidence of thrombocytopenia during treatment with hog mucosa and beef lung heparin.
129 patients with thrombosis were treated with heparin for 5 d and followed with platelet counts and coagulation examinations. Of 77 patients treated with 2 different brands of hog mucosa heparin, only 1 developed persistent thrombocytopenia below 100 X 10(9)/1. Of 52 patients treated with beef lung heparin, 1 patient developed thrombocytopenia. No patient developed intravascular coagulation or activated fibrinolysis during heparin treatment.
D000368:Aged; D000818:Animals; D001780:Blood Coagulation Tests; D002417:Cattle; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D010976:Platelet Count; D011655:Pulmonary Embolism / Q000188:drug therapy; D013045:Species Specificity; D013552:Swine; D013921:Thrombocytopenia / Q000139:chemically induced*; D013924:Thrombophlebitis / Q000188:drug therapy; D013997:Time Factors
D005338:Fibrin Fibrinogen Degradation Products; D006493:Heparin