Correlation of the effects of bretylium, guanethidine, and N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea (P-286) on the H+ electrochemical gradient across the chromaffin granule membrane and on chromaffin granule function.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001949:Bretylium Compounds / Q000494:pharmacology*; D002395:Catecholamines / Q000378:metabolism; D002417:Cattle; D002837:Chromaffin Granules / Q000187:drug effects / Q000378:metabolism*; D002838:Chromaffin System / Q000378:metabolism*; D006145:Guanethidine / Q000494:pharmacology*; D006859:Hydrogen / Q000378:metabolism; D008564:Membrane Potentials / Q000187:drug effects; D008566:Membranes / Q000378:metabolism; D014508:Urea / Q000031:analogs & derivatives* / Q000494:pharmacology
D001949:Bretylium Compounds; D002395:Catecholamines; C001003:N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea; D006859:Hydrogen; D000255:Adenosine Triphosphate; D014508:Urea; D006145:Guanethidine