Malignant hyperthermia and the fluoride-resistant gene.
One hundred and six individuals from 33 families with a history of malignant hyperthermia have been investigated for plasma cholinesterase variants. An increased frequency of the fluoride-resistant gene has been found. Although an adequate explanation for our results is elusive, some hypotheses are discussed.
D002802:Cholinesterases / Q000097:blood / Q000235:genetics*; D005459:Fluorides; D005787:Gene Frequency; D005796:Genes; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008305:Malignant Hyperthermia / Q000201:enzymology / Q000235:genetics*
D002802:Cholinesterases; D005459:Fluorides