A canine testicular tumor resembling gonadoblastoma.
A tumor of the left testicle resembling a gonadoblastoma was an incidental finding at necropsy in a 15-year-old male Shetland Sheepdog. This neoplasm was characterized by discrete intratubular aggregates of intimately mixed germ cells and smaller cells resembling Sertoli cells. The latter small cells often formed a single cell layer surrounding the margin of eosinophilic, PAS-positive Call-Exner-like bodies. Electron microscopy showed these bodies to be composed of whorled laminae resembling basement membrane.
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004407:Dysgerminoma / Q000648:ultrastructure / Q000662:veterinary*; D006651:Histocytochemistry; D008297:Male; D013736:Testicular Neoplasms / Q000648:ultrastructure / Q000662:veterinary*