Occurrence of enzyme-immunoglobulin complexes in chronic inflammatory bowel disease.
The presence of circulating enzyme-immunoglobulin complexes was investigated in serum samples of patients with inflammatory bowel disease. In a series of 20 patients with ulcerative colitis AP-Ig complexes were demonstrated in three and LDH-Ig complexes were observed in two others. No AP-Ig or LDH-Ig complexes were found in the sera of 25 patients with Crohn's disease. These findings suggest a relationship between enzyme-immunoglobulin complex formation and ulcerative colitis.
D000328:Adult; D000469:Alkaline Phosphatase; D003093:Colitis, Ulcerative / Q000201:enzymology* / Q000276:immunology; D003424:Crohn Disease / Q000201:enzymology / Q000276:immunology; D004587:Electrophoresis, Agar Gel; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D007136:Immunoglobulins; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D008297:Male; D008875:Middle Aged; D011234:Precipitins
D007074:Immunoglobulin G; D007136:Immunoglobulins; D007527:Isoenzymes; D011234:Precipitins; D007770:L-Lactate Dehydrogenase; D000469:Alkaline Phosphatase