Conjunctival inflammation and amyloidosis in allergic granulomatosis and angiitis (Churg-Strauss syndrome).
A 37-year-old woman developed nodular, waxy conjunctival lesions associated with the exacerbation of Churg-Strauss syndrome. Conjunctival and skin biopsy specimens demonstrated a diffuse inflammatory process composed of eosinophils, plasma cells, lymphocytes, and focal collections of histiocytes. There were amyloid deposits in the conjunctiva and skin. To our knowledge, this is the first report of conjunctival changes and amyloidosis associated with the Churg-Strauss syndrome.
D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D001249:Asthma / Q000150:complications*; D003231:Conjunctivitis / Q000150:complications* / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000150:complications*; D006801:Humans; D012871:Skin Diseases / Q000150:complications; D013577:Syndrome; D014657:Vasculitis / Q000150:complications* / Q000473:pathology