title: [Compounds with antitumor activity. V. Hydrazone derivatives of 5-formylimidazo(2,1-b)thiazoles and 6-substituted 2,3-dihydro-5-formylimidazo(2,1-b)thiazoles].
abstract: The synthesis of 2,3-dihydro-5-formylimidazo[2,1-b]thiazoles with different substituents at position 6 (CH3, C6H5, Cl, Br) is reported; thiosemicarbazones and tosylhydrazones were prepared from these aldehydes and from the 2,3-unsaturated analogues: these derivatives, submitted to a preliminary test, did not show significant antileukemic activity.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007939:Leukemia L1210 / Q000188:drug therapy; D051379:Mice; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D013844:Thiazoles
vernacular_title: Composti a presunta attività antitumorale. Nota V - Derivati idrazonici di 5-formilimidazo[2,1-b]tiazoli e 2,3-diidro-5-formilimidazo[2,1-b]tiazoli 6-sostituiti.