Ocular melanocytosis and angioid streaks.
Unilateral angioid streaks of the ocular fundus with homolateral ocular melanocytosis in a 49-year-old white woman are reported. The findings are substantiated by fluorescein angiography. The local changes related to ocular melanocytosis probably precipitated the formation of angioid streaks in the genetically predisposed patient. Two greyish-yellow patches were also found on ophthalmoscopy of the involved eye. One of these, located in the paramacular region, exhibited definite progression, and transformed into a disciform lesion without implicating the macula. The presence of these likely precursors of angioid streaks about the macula is more ominous. A comment about the relationship between melanocytosis, angioid streaks, and phakomatoses is added.
D000328:Adult; D000793:Angioid Streaks / Q000473:pathology*; D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology*