title: Streptococcal infection in young pigs. V. An immunogenic polysaccharide from Streptococcus suis type 2 with particular reference to vaccination against streptococcal meningitis in pigs.
abstract: Of 17 pigs vaccinated with STreptococcus suis type-2 capsular polysaccharide plus Freund's Incomplete Adjuvant, all developed opsonizing antibody against Str. suis type 2. Of 14 pigs vaccinated with type-2 polysaccharide alone, 4 (possibly 6) developed opsonizing antibody. It is possible that some pigs vaccinated with polysaccharide plus Freund's Incomplete Adjuvant developed opsonizing antibody in response to a 'booster' injection of polysaccharide alone. Of 21 unvaccinated control pigs, late bleeding from 3 showed opsonizing activity against Str. suis type 2.
mesh_terms: D000818:Animals; D016667:Bacterial Capsules; D005620:Freund's Adjuvant / Q000494:pharmacology; D007114:Immunization / Q000379:methods / Q000662:veterinary*; D008581:Meningitis / Q000276:immunology / Q000662:veterinary*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013290:Streptococcal Infections / Q000276:immunology / Q000662:veterinary*; D013291:Streptococcus / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology*
chemical_list: D011135:Polysaccharides, Bacterial; C028096:capsular polysaccharide, Streptococcus suis type 2; D005620:Freund's Adjuvant