title: Comparison of mercury levels in maternal blood, fetal cord blood, and placental tissues.
abstract: Previous studies have reported that mercury accumulates in cord blood during pregnancy. This study was carried out to determine where in cord blood the mercury accumulates, i.e., in cord erythrocytes, in cord plasma, or in both, and to determine whether the predominant form of mercury which accumulates is methyl  or inorganic mercury. From our data it is clear that methyl mercury accumulates in cord erythrocytes: A total of 30% more methyl mercury was found in fetal erythrocytes than in maternal erythrocytes. Also correlation analysis of the methyl mercury levels in maternal and fetal erythrocytes showed a strong correlation (r = 0.87). In regard to inorganic mercury, the highest concentration was found in the placenta, suggesting a barrier role, but a significant correlation (r = 0.62) was also found between the maternal and fetal plasma levels of inorganic mercury. Moreover, the inorganic mercury concentration per gram of plasma was higher in fetal cord plasma than in maternal plasma. Overall, the relative levels of methyl and inorganic mercury reported here varied considerably in materrnal and fetal erythrocytes, plasma, and in the placenta, but all of the levels were low (<6 ng Hg/gm of tissue) and in agreement with Øtotal¿ mercury levels reported by others.
mesh_terms: D004912:Erythrocytes / Q000032:analysis; D005260:Female; D005312:Fetal Blood / Q000032:analysis*; D006801:Humans; D008431:Maternal-Fetal Exchange; D008628:Mercury / Q000032:analysis* / Q000097:blood; D008767:Methylmercury Compounds / Q000032:analysis; D010920:Placenta / Q000032:analysis*; D010949:Plasma / Q000032:analysis; D011247:Pregnancy
chemical_list: D008767:Methylmercury Compounds; D008628:Mercury