Lysosomal acid phosphatase decrease in nutritional encephalopathy in chicks.
Encephalopathy was induced in 14-day-old chicks by a vitamin E-deficient diet containing 15% thermally oxidized safflower oil. Bound acid phosphatase activity in the cerebellum was markedly lower in affected chicks than in vitamin E-supplied control chicks. Free activity also tended to be lower in the deficient group. There were no differences in enzyme activities of cerebrum and liver between deficient and control chicks.
D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D001927:Brain Diseases / Q000201:enzymology / Q000662:veterinary*; D002526:Cerebellar Diseases / Q000201:enzymology / Q000662:veterinary; D002645:Chickens / Q000378:metabolism*; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D011201:Poultry Diseases / Q000201:enzymology*; D012450:Safflower Oil; D014811:Vitamin E Deficiency / Q000201:enzymology / Q000662:veterinary*
D012450:Safflower Oil; D000135:Acid Phosphatase