Isolation and characterization of cyanogen bromide fragments of the A and B chains of the antitumor toxin ricin D.
Both the A and B chains of ricin D consist of four CNBr fragments. These fragments have been isolated from the separated chains of S-carboxymethylated ricin D obtained from the small bean variety of Ricinus communis. The peptides have been characterized by molecular weight, amino acid composition and amino terminal sequence. A unique order of the peptides is evident for each chain. These sequence data are compared with those obtained for ricin D isolated from the large bean variety.
D000595:Amino Acid Sequence; D001322:Autoanalysis; D003488:Cyanogen Bromide; D046911:Macromolecular Substances; D010446:Peptide Fragments / Q000032:analysis; D012276:Ricin
D046911:Macromolecular Substances; D010446:Peptide Fragments; D012276:Ricin; D003488:Cyanogen Bromide