HlA antigens and steroid responsive nephrotic syndrome of childhood.
Fifty-four unrelated children with steroid responsive nephrotic syndrome of childhood were studied for 24 alleles at the HLA--A and B loci. A significantly increased incidence of HLA--B8 (Pc less than 0.01) was observed compared to controls. No association between response to cyclophosphamide therapy and HLA antigens was seen.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000627:therapeutic use; D006680:HLA Antigens / Q000235:genetics*; D006238:Haploidy; D006801:Humans; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*
D000305:Adrenal Cortex Hormones; D006680:HLA Antigens; D003520:Cyclophosphamide