Destruction of cytochrome P-450 by olefins: N-alkylation of prosthetic heme.
D000475:Alkenes / Q000378:metabolism*; D000478:Alkylation; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006418:Heme / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism; D008297:Male; D011166:Porphyrins / Q000378:metabolism*; D051381:Rats
D000475:Alkenes; D011166:Porphyrins; D006418:Heme; D003577:Cytochrome P-450 Enzyme System