A simplified method for assessing drug effects on gastric emptying in rats.
A method is described to determine the effects of experimental compounds on gastric emptying in rats. The technique, using a methylcellulose-based test meal, is simple, versatile and reliable. Data are presented to show the utility of the method in demonstrating both enhancement and inhibition of gastric emptying.
D000818:Animals; D005260:Female; D005502:Food; D005746:Gastric Emptying / Q000187:drug effects*; D006024:Glycopyrrolate / Q000494:pharmacology; D007700:Kinetics; D008787:Metoclopramide / Q000494:pharmacology; D051381:Rats
D008787:Metoclopramide; D006024:Glycopyrrolate