title: Effects of Varidase buccal tablets on the sputum.
abstract: Samples of sputum were collected from ten patients with chronic respiratory diseases following treatment with Varidase (streptodornase and streptokinase) buccal tablets, four tablets per day for a period of seven days, and were compared with specimens obtained before the therapy in terms of rheological and cytochemical parameters. The study revealed a tendency for the respiratory secretion to show a lowered yield point and a decrease in mucous fibers after the therapy, thus suggesting, to some extent, the efficacy of the drug as an expectorant.
mesh_terms: D000328:Adult; D000368:Aged; D005100:Expectorants / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012212:Rheology; D013183:Sputum / Q000032:analysis / Q000187:drug effects* / Q000502:physiology; D013299:Streptodornase and Streptokinase / Q000008:administration & dosage / Q000494:pharmacology*; D013607:Tablets
chemical_list: D005100:Expectorants; D013607:Tablets; D013299:Streptodornase and Streptokinase