title: Combined pre-operative telecobalt therapy and supraglottic laryngectomy.
abstract: At Groote Schuur Hospital, Cape Town, over a 5-year period (1974 to 1978) 15 patients with squamous cell carcinoma of the larynx or hypopharynx have had planned 2,000 Rad Telecobalt therapy followed by supraglottic horizontal laryngectomy. Five patients following surgery had a further 3,600--4,000 Rad Telecobalt therapy. The peri-operative complications, in addition to those of whole organ resection, included debilitating laryngeal incompetence in three patients, two of whom underwent total laryngectomy. All 15 patients have remained free of recurrent disease for 2 years and 10 have been free for 3 or more years. One patient died 4 years after surgery from a primary bronchial carcinoma.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007013:Hypopharynx; D007822:Laryngeal Neoplasms / Q000628:therapy*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000628:therapy*; D011183:Postoperative Complications; D011300:Preoperative Care; D011867:Radioisotope Teletherapy
chemical_list: D003037:Cobalt Radioisotopes