title: Frequency of private electrophoretic variants and indirect estimates of mutation rate in Papua New Guinea.
abstract: Data on rare and private electrophoretic variants have been used to estimate mutation rates for populations belonging to 55 language groups in Papua New Guinea. Three different methods yield values of 1.42 x 10(-6), 1.40 x 10(-6), and 5.58 x 10(-6)/locus per generation. The estimates for three islands populations off the north coast of New Guinea--Manus, Karkar, and Siassi--are much lower. The variability in mutation rates estimated from rare electrophoretic variants as a function of population size is discussed. The mean mutation rate in Papua New Guinea is less than half the estimates obtained for Australian Aborigines and Amerindians.
mesh_terms: D004798:Enzymes / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D008433:Mathematics; D008957:Models, Genetic; D009154:Mutation; D009512:New Guinea
chemical_list: D004798:Enzymes