Evidence for a direct inhibitory effect of glucocorticoids on the activity of phospholipase A2 as a further possible mechanism of some actions of steroidal anti-inflammatory drugs.
D000287:Administration, Topical; D000450:Aldosterone / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D003907:Dexamethasone / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005938:Glucocorticoids; D010740:Phospholipases / Q000037:antagonists & inhibitors*; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D054467:Phospholipases A2; D011453:Prostaglandins / Q000096:biosynthesis / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011453:Prostaglandins; D000450:Aldosterone; D003907:Dexamethasone; D010740:Phospholipases; D010741:Phospholipases A; D054467:Phospholipases A2