Herbimycin B, a new benzoquinonoid ansamycin with anti-TMV and herbicidal activities.
A new benzoquinonoid ansamycin, herbimycin B was isolated from the culture broth of Streptomyces hygroscopicus No. AM-3672, a herbimycin A-producing strain. Herbimycin B showed potent anti-TMV activity. Herbicidal effect of herbimycin B was less than that of herbimycin A.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000096:biosynthesis / Q000494:pharmacology*; D016227:Benzoquinones; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006540:Herbicides; D047029:Lactams, Macrocyclic; D007928:Lethal Dose 50; D051379:Mice; D011809:Quinones / Q000032:analysis / Q000096:biosynthesis / Q000494:pharmacology; D017828:Rifabutin / Q000031:analogs & derivatives; D013302:Streptomyces / Q000378:metabolism; D014027:Tobacco Mosaic Virus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D016227:Benzoquinones; D006540:Herbicides; D047029:Lactams, Macrocyclic; D011809:Quinones; D017828:Rifabutin; C020754:herbimycin