Sites of steroid production in the polycystic ovary.
Tissue culture of slices of polycystic ovaries shows that androstenedione and oestradiol are mostly produced by the cortical, cyst-containing portions, with little steroid production in vitro by medullary stromal tissues.
D000293:Adolescent; D000328:Adult; D000735:Androstenedione / Q000096:biosynthesis*; D046508:Culture Techniques; D004958:Estradiol / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D010053:Ovary / Q000378:metabolism*; D011085:Polycystic Ovary Syndrome / Q000378:metabolism*
D000735:Androstenedione; D004958:Estradiol