The cardiovascular effects of pancuronium during halothane and cyclopropane anaesthesia.
The effect of pancuronium 0.1 mg/kg i.v. on heart rate (HR) and mean arterial blood pressure were investigated in two groups of eight patients, each receiving  inhalational anaesthesia with either  halothane or cyclopropane. A more pronounced effect on HR in the cyclopropane group with a mean increase of 104% occurred. The mean increase in the halothane group was 54%. There was a statistically significant difference (P less than 0.05) between the HR increases The vagolytic effect of pancuronium and the influence of halothane and cyclopropane on the autonomic nervous system are discussed.
D000328:Adult; D000758:Anesthesia; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001794:Blood Pressure / Q000187:drug effects; D003521:Cyclopropanes; D005260:Female; D006221:Halothane; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010197:Pancuronium / Q000494:pharmacology*
D003521:Cyclopropanes; D010197:Pancuronium; D006221:Halothane