Vitamin E inhibits arachidonic acid induced mortality and renal IgM deposition in rabbits.
Prior administration of DL-alpha tocopherol inhibits arachidonic acid induced mortality in rabbits. Glomerular deposition of fibrin and IgM due to arachidonic acid infusion is also inhibited by prior administration of DL-alpha tocopherol.
D000818:Animals; D001095:Arachidonic Acids / Q000037:antagonists & inhibitors / Q000633:toxicity*; D005337:Fibrin / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D014810:Vitamin E / Q000494:pharmacology*
D001095:Arachidonic Acids; D007075:Immunoglobulin M; D014810:Vitamin E; D005337:Fibrin