Organ of Corti-specific polypeptides: OCP-I and OCP-II.
Two polypeptides, OCP-I and OCP-II, specific to the organ of Corti of the quinea pig and the rate, were detected by two-dimensional polyacrylamide gel electrophoresis. They were neither present in other inner ear structures, nor in other organs tested. The two polypeptides constitute a substantial portion of the total protein of the organ of Corti. Both inner and outer layer of the organ of Corti contained approximately equal amounts of OCP-I and OCP-II. The molecular weights of OCP-I and OCP-II are 37,000 and 22,500 daltons, respectively. The corresponding pI values are 4.9 and 5.1, respectively. in addition, actin and tubulin were detected in both layers of the organ of Corti.
D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D006168:Guinea Pigs; D008970:Molecular Weight; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009925:Organ of Corti / Q000032:analysis*; D010455:Peptides / Q000032:analysis*; D051381:Rats
D009419:Nerve Tissue Proteins; D010455:Peptides