Antibiotic therapy for the Bacteroidaceae in post-cesarean section infections.
One hundred patients were treated for postpartum endometritis with ampicillin and clindamycin. Fifty patients were analyzed retrospectively and 50 prospectively for therapeutic response and development of late infectious sequelae. Seventy-eight patients exhibited an acceptable clinical response. One patient developed a wound infection from Staphylococcus aureus, which responded to drainage. The remaining 21 patients responded to the addition of an aminoglycoside. No patient developed a pelvic abscess or septic thrombophlebitis. The therapeutic response of the 2 groups treated with ampicillin and clindamycin is contrasted with the results derived from the traditional antibiotic regimen of a penicillin and an aminoglycoside.
D000667:Ampicillin / Q000627:therapeutic use; D001442:Bacteroides Infections / Q000188:drug therapy* / Q000209:etiology; D002585:Cesarean Section / Q000009:adverse effects*; D002981:Clindamycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007612:Kanamycin / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy* / Q000209:etiology; D012189:Retrospective Studies
D010406:Penicillins; D002981:Clindamycin; D007612:Kanamycin; D000667:Ampicillin