title: [Pharmacokinetic studies of sulfamerazine-Na, sulfaperine-Na and sulfadimidine-Na in the hen].
abstract: The pharmacokinetic properties of sulphaperine-sodium, Mebacid 200, and sulphadimidine-sodium were experimentally established from fowl and mathematically objectivated. The highest half-life for elimination, coupled with low protein fixation, was recorded from sulphadimidine, by comparison of the above three sulphonamides. These data were used in dosage calculations for clinical testing.
mesh_terms: D000107:Acetylation; D000284:Administration, Oral / Q000662:veterinary; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D005260:Female; D007536:Isomerism; D007700:Kinetics; D008954:Models, Biological; D011485:Protein Binding; D013416:Sulfamerazine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D013418:Sulfamethazine / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*
chemical_list: D013418:Sulfamethazine; C012049:sulfaperine; D013416:Sulfamerazine
vernacular_title: Pharmakokinetische Untersuchungen von Sulfamerazin-Na, Sulfaperin-Na und Sulfadimidin-Na beim Huhn.