Metoclopramide-induced gastric emptying in patients with anorexia nervosa.
Study of gastric retention of 99mTc-labeled meal by gamma camera is a reliable technic. Patients with anorexia nervosa were found to have increased gastric retention or delayed gastric emptying of a standard meal. Administration of metoclopramide acutely enhanced gastric emptying and chronically improved the weight and gastrointestinal symptoms of patients with anorexia nervosa. The gastrointestinal symptoms most significantly improved were: intolerance to meals, postprandial epigastric pain, belching, vomiting, anorexia and early satiety. Metoclopramide should be considered as an adjunct treatment in patients with anorexia nervosa.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects*; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000627:therapeutic use*; D008875:Middle Aged; D010528:Peristalsis / Q000187:drug effects
D008787:Metoclopramide