Comparison of the urea cycle in conventional and germ-free mice.
The urea cycle in the liver of conventional mice was compared with that of germ-free mice. Among the urea cycle enzymes and urea cycle-related substances, only ornithine in the liver of the conventional mice was markedly more abundant than in that of the germ-free mice. The significance of this finding was supported by the comparison of the urea synthesis in the liver slices from these two types of mice.
D000818:Animals; D005856:Germ-Free Life; D008099:Liver / Q000378:metabolism; D051379:Mice; D008813:Mice, Inbred ICR; D009952:Ornithine / Q000378:metabolism; D014508:Urea / Q000378:metabolism*
D014508:Urea; D009952:Ornithine