[Macrophage migration inhibition reaction in Marseilles fever].
Delayed type hypersensitivity (DTH) was studied in the macrophage migration inhibition test, antibody titers in the CFT and functional activity of spleen macrophages, obtained from guinea-pigs infected with R. conori, in cell cultures. No direct correlation between antibody synthesis and functional macrophage activity accompanied by the development of DTH was revealed. The most pronounced protective function of macrophages could be observed during the decrease of antibody titers and the extinction of DTH.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001907:Boutonneuse Fever / Q000276:immunology*; D002464:Cell Migration Inhibition; D003168:Complement Fixation Tests; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D008811:Mice, Inbred DBA / Q000276:immunology; D010587:Phagocytosis; D012288:Rickettsiaceae Infections / Q000276:immunology*; D013154:Spleen / Q000276:immunology
D000907:Antibodies, Bacterial
Reaktsiia tormozheniia migratsii makrofagov pri éksperimental'noĭ Marsel'skoĭ likhoradke.