Primary mediastinal embryonal carcinoma in association with Klinefelter's syndrome.
Germ cell tumors, particularly those of extragonadal origin, have a rare and only recently recognized association with Klinefelter's syndrome. A case of a primary mediastinal embryonal cell carcinoma in a 16-year-old male with Klinefelter's syndrome is reported.
D000293:Adolescent; D004198:Disease Susceptibility; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications*; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000235:genetics / Q000473:pathology; D013724:Teratoma / Q000150:complications* / Q000235:genetics / Q000473:pathology