title: The value of whole lung tomography in the early detection of metastatic disease in patients with renal cell carcinoma and testicular tumors.
abstract: The value of whole lung tomography was compared to chest x-rays in patients with renal cell carcinoma and germ cell testicular tumors. We studied 83 patients with testicular tumors and 34 with renal cell carcinoma. At least 1 metastatic lesion was present on whole lung tomography in 11 of 64 patients (17 per cent) with testicular tumors and 2 of 21 (10 per cent) with renal cell carcinoma who had negative chest x-rays. Of the patients with a solitary lesion on the chest x-ray 3 of 10 (30 per cent) with testicular tumor and 5 of 11 (45 per cent) with renal cell carcinoma had multiple metastatic lesions on whole lung tomograms. Falsely positive chest x-rays were noted in 6 of 15 patients (40 per cent) with renal cell carcinoma and 6 of 16 (37 per cent) with testis tumor. These falsely positive results were caused by overlapping shadows, vessels or granulomas.
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary; D004407:Dysgerminoma / Q000000981:diagnostic imaging / Q000556:secondary; D006801:Humans; D007680:Kidney Neoplasms; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D013724:Teratoma / Q000000981:diagnostic imaging / Q000556:secondary; D013736:Testicular Neoplasms; D014056:Tomography, X-Ray