title: Barbiturate-induced submassive hepatic necrosis. Report of a case and review of the literature.
abstract: A case of barbiturate-induced submassive hepatic necrosis is presented and the literature is reviewed. The patient's clinical presentation, histologic features on liver biopsy and favorable course after stopping the drug suggest that barbiturates can be added to the list of agents which can cause submassive hepatic necrosis.
mesh_terms: D000368:Aged; D001706:Biopsy; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D009336:Necrosis; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy
chemical_list: D010672:Phenytoin