title: Nucleoside transport in human erythrocytes. Apparent molecular weight of the nitrobenzylthioinosine-binding complex estimated by radiation-inactivation analysis.
abstract: Nitrobenzylthioninosine, a potent nucleoside-transport inhibitor, binds specifically to functional nucleoside transport sites. Irradiation of freeze-dried human erythrocyte membranes with high-energy electrons was used to estimate the apparent molecular weight of the nitrobenzylthioninosine-binding complex in situ. The nitrobenzylthioinosine-binding complex had an apparent mol.wt. of 122000.
mesh_terms: D001665:Binding Sites / Q000528:radiation effects; D001692:Biological Transport; D004583:Electrons; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000528:radiation effects; D004912:Erythrocytes / Q000378:metabolism*; D005612:Freeze Drying; D006801:Humans; D066298:In Vitro Techniques; D007288:Inosine / Q000031:analogs & derivatives*; D008970:Molecular Weight; D009705:Nucleosides / Q000097:blood*; D010315:Particle Accelerators; D013868:Thioinosine / Q000031:analogs & derivatives* / Q000378:metabolism
chemical_list: D009705:Nucleosides; D013868:Thioinosine; D007288:Inosine; C001789:4-nitrobenzylthioinosine