Fractionation of heparin by chromatography on immobilized thrombin. Correlation between the anticoagulant activity of the fractions and their content of heparin with high affinity for antithrombin.
D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology*; D000991:Antithrombins; D001665:Binding Sites; D002417:Cattle; D005591:Chemical Fractionation; D002845:Chromatography; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D006493:Heparin; D009994:Osmolar Concentration; D013917:Thrombin / Q000494:pharmacology*
D000925:Anticoagulants; D000991:Antithrombins; D006493:Heparin; D013917:Thrombin