title: Dietary management of chronic renal failure with oral amino acids.
abstract: 6 patients in end-stage renal failure of varying aetiologies have been studied on low protein dietary regiments according to a P 6 formulation. All patients had part of their daily protein allowance substituted by an essential amino acid capsule also containing histidine and glutamic acid. All patients were maintained in nutritional balance as a result of the regiments prescribed. No toxic effects were noted and patient compliance was good. Our studies suggest the amino acid formulation given is safe and did not cause any fluctuations in patient plasma amino acid profiles. Our studies suggest an improved method of low protein dietary management for chronic renal failure patients together with a greater flexibility and wider range of prescribing possibilities. It is recommended that amino acid supplements according to the formula produced here constitute an improvement on currently prescribed Giovannetti regimens.
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000009:adverse effects / Q000627:therapeutic use*; D000601:Amino Acids, Essential / Q000627:therapeutic use; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000592:standards; D005260:Female; D005971:Glutamates / Q000627:therapeutic use; D006639:Histidine / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000378:metabolism; D009753:Nutritive Value; D010349:Patient Compliance
chemical_list: D000596:Amino Acids; D000601:Amino Acids, Essential; D004044:Dietary Proteins; D005971:Glutamates; D006639:Histidine; D009584:Nitrogen