[Relationship between cysteinesulfinate and aspartate transport in mitochondria].
L-CSA and L-Aspartate inhibit each other's transport in the mitochondria in a competitive manner. The D-isomers have very little effect. It is proposed that the two amino acids are transported by a common translocator, presumable the glutamate-aspartate carrier.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D001224:Aspartic Acid / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D003545:Cysteine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D007536:Isomerism; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D009249:NADP / Q000378:metabolism; D018377:Neurotransmitter Agents; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D013441:Sulfinic Acids / Q000378:metabolism / Q000494:pharmacology
D018377:Neurotransmitter Agents; D013441:Sulfinic Acids; D001224:Aspartic Acid; D009249:NADP; D003545:Cysteine; D001205:Ascorbic Acid; C013461:cysteine sulfinic acid
Interrelazione fra il trasporto di cisteinsulfinato e aspartato nei mitocondri.