title: Primary malignant tumours of the anus.
abstract: Primary malignant anal tumours were studied in 6 men and 11 women at the Health Sciences Centre in Winnipeg between Jan. 1, 1968 and Dec. 31, 1977. The patients ranged in age from 46 to 85 years (mean 64 years). Histologically, over 70% of tumours were either cloacogenic or squamous carcinomas. A variety of other lesions were encountered, reflecting the complex embryologic development of this region. The most frequent presenting complaints were a mass at the anus and rectal bleeding. Abdominoperineal resection, with or without radiotherapy, was the preferred treatment, but in a few cases local excision was effective. During the follow-up period, eight patients died, an average of 2 years after diagnosis. The remaining nine patients have survived an average of 6 years; two have recurrent tumour.
mesh_terms: D000368:Aged; D001005:Anus Neoplasms / Q000175:diagnosis* / Q000401:mortality; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000401:mortality; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged