title: Analysis of proteins of the stria vascularis of the normal and the waltzing guinea pig.
abstract: Proteins of the stria vascularis of the normal and the genetically deaf waltzing guinea pig were analysed by one and two-dimensional acrylamide gel electrophoresis. Cochlear proteins were labeled in vivo by replacing the perilymph with a solution containing radioactive precursors. With the two-dimensional analysis, more than 200 polypeptides were resolved. Proteins that are exposed on the endolymphatic surface of the stria vascularis were identified by lactoperoxidase-catalysed iodination. Seven polypeptides were identified with this technique. No consistent changes in protein patterns of the stria vascularis from the waltzing guinea pig were detected.
mesh_terms: D000818:Animals; D003051:Cochlea / Q000032:analysis*; D003638:Deafness / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D004711:Endolymphatic Duct / Q000032:analysis; D006168:Guinea Pigs; D010455:Peptides / Q000032:analysis; D011506:Proteins / Q000032:analysis*; D013316:Stria Vascularis / Q000032:analysis*
chemical_list: D010455:Peptides; D011506:Proteins