In-vitro blood compatibility studies on a new polymer-coated charcoal for haemoperfusion.
The blood compatibility of new polyhema-coated charcoal (Biotec) has been studied in an in-vitro haemoperfusion circuit. The mean inlet platelet levels after 4 hours of perfusion were 99.5 +/- SE 4.2% of the initial value and mean white cell levels were 81.9 +/- SE 5.8% of initial. No rises in Swank screen filtration pressure were detected. Initial evaluation of this charcoal in patients with fulminant hepatic failure should be possible without platelet-protective agents.
D002606:Charcoal; D006464:Hemoperfusion / Q000295:instrumentation*; D006801:Humans; D008107:Liver Diseases / Q000628:therapy; D010976:Platelet Count; D011108:Polymers; D013997:Time Factors
D011108:Polymers; D002606:Charcoal