[Administration of cyclophosphamide determines the lowering of serum cholinesterase levels].
Reduced plasma cholinesterase activity results in prolongation of the neuromuscolar block caused by succinylcholine and in prolonged apnoea. Cyclophosphamide administration, even at low dose, causes a prolonged fall of serum cholinesterase levels. This effect induced to take the necessary precautions in patients submitted to preoperative chemotherapy.
D002802:Cholinesterases / Q000097:blood*; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007700:Kinetics; D009369:Neoplasms / Q000188:drug therapy / Q000201:enzymology / Q000601:surgery; D012306:Risk
D003520:Cyclophosphamide; D002802:Cholinesterases
La somministrazione di ciclofosfamide determina abbassamento dei livelli della colinesterasi sierica.