[Changes in hemodynamics and oxygen supply to the body following massive administration of homologous blood by means of an arteriovenous shunt].
In experiments on dogs, exchange normovolemic perfusion of homologous blood by means of arteriovenous bypass resulted in disturbances of blood circulation and development of circulatory hypoxia. This was manifested in a significant slowing of the blood flow, a decrease in cardiac output an abrupt increase in general peripheral resistance that allowed arterial pressure to be maintained at a physiological level. Compensation of hypoxia occurred at the expense of a rise in O2 utilization from inflowing blood.
D000818:Animals; D001166:Arteriovenous Shunt, Surgical; D001794:Blood Pressure; D001810:Blood Volume; D002302:Cardiac Output; D002318:Cardiovascular Diseases / Q000209:etiology*; D004285:Dogs; D006439:Hemodynamics; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D013577:Syndrome; D013997:Time Factors; D065227:Transfusion Reaction; D014655:Vascular Resistance
D010100:Oxygen
Izmenenie gemodinamiki i kislorodnogo snabzheniia organizma pri massivnom vvedenii gomologichnoĭ krovi s pomoshch'iu arteriovenoznogo shunta.