Giant cell tumour of the femur: en bloc resection and replacement with homologous graft.
The author reports the case of a 21-year-old pregnant woman who underwent hemiarthroplasty with a homologous graft for a giant cell tumour of the lower end of the femur. Recovery was smooth and bony union of the graft to the host segment was solid within 3 months. At follow-up 10 years after the operation the patient had no pain, swelling, deformity or limp. She had 120 degrees flexion in the knee and full extension but there was moderate lateral and anteroposterior instability. Such en bloc resection and primary replacement with homologous graft may have an important role to play in the treatment of certain bone tumours such as giant cell tumours.
D000328:Adult; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery*; D005269:Femur / Q000637:transplantation*; D005870:Giant Cell Tumors / Q000601:surgery*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D014184:Transplantation, Homologous