title: Introduction to resection of musculoskeletal sarcomas.
abstract: Resections for high-grade musculoskeletal sarcomas are feasible. For osteosarcomas, they appear to be safe if performed properly. For other sarcomas, there are insufficient data. A major issue is whether such procedures are worthwhile. For lesions of the upper extremity, resections are clearly advantageous over amputations. For lesions in the lower extremities proximal to the knee joint, resection is usually preferable, while those below the knee joint are best amputated. Lesions involving the knee are the most challenging problems.
mesh_terms: D000671:Amputation, Surgical; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D009135:Muscular Diseases / Q000601:surgery*; D009369:Neoplasms / Q000473:pathology / Q000601:surgery; D011182:Postoperative Care; D012509:Sarcoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*
chemical_list: D000970:Antineoplastic Agents