title: Fetal heart rate changes after accidental intrauterine lidocaine.
abstract: Fetal heart rate (FHR) decelerations resembling post-paracervical block (PCB) bradycardia were observed immediately after the inadvertent intrauterine injection of lidocaine hydrochloride. A review of the pathophysiology of post-PCB bradycardia is presented. The administration of a local anesthetic, either into the paracervical tissues or directly into the uterine cavity, may precipitate FHR decelerations principally, through arterial vasoconstriction with subsequent reflex responses and/or hypoxia in the fetus.
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical / Q000009:adverse effects*; D001919:Bradycardia / Q000139:chemically induced*; D005260:Female; D005318:Fetal Heart / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D011247:Pregnancy; D014599:Uterus
chemical_list: D008012:Lidocaine