[Effects of a polysaccharide extracted from a red alga (Bonnemaisonales) on mononucleate phagocytes in several rodents].
"Armatan" an acidic sulfated polysaccharide isolated from a red algae (Asparagopsis Armata), has a marked affinity for the Mononuclear Phagocytes System. Its activity seems fairly well established. Indeed, it sets off a series of evolutionary cellular processes beginning with an accumulation of monocytes at the inflammatory injection site; these cells are then replaced by macrophages over several weeks which are progressively substituted by fibroblasts, thereby inducing a final fibro-cicatricial reaction. The inductive effect of Armatan in this cellular evolution is discussed.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D006168:Guinea Pigs; D007249:Inflammation / Q000139:chemically induced; D010586:Phagocytes / Q000187:drug effects*; D011134:Polysaccharides / Q000032:analysis*; D051381:Rats; D000461:Rhodophyta / Q000032:analysis*
D011134:Polysaccharides; C028510:armatan
Effects d'un polysaccharide extrait d'une algue rouge (Bonnemaisionaile) sur les phagocytes mononuclees de quelques rongeurs.