Polymyalgia rheumatica in a husband and wife.
The case histories of an unrelated husband and wife in whom polymyalgia rheumatica developed within one month are described. In the wife, giant-cell arteritis was present. The clinical courses were similar and there was a typical good response to treatment with prednisone. Both patients were HLA-B8. Only the husband had positive hepatitis-Bs antibody. The aetiology of the disease is discussed in relation to tissue antigens and hepatitis-B infection.
D000368:Aged; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications; D006680:HLA Antigens; D006510:Hepatitis B Antibodies / Q000032:analysis; D006801:Humans; D008297:Male; D011111:Polymyalgia Rheumatica / Q000235:genetics*
D006680:HLA Antigens; D006510:Hepatitis B Antibodies