title: Prevalence of rabies virus in foxes trapped in the Canadian Arctic.
abstract: Brains and salivary glands of 521 trapped arctic foxes (Alopex lagopus) submitted from four different settlement areas in the Northwest Territories were examined for rabies by the standard fluorescent antibody and mouse inoculation tests. Rabies antigen was present in 44 of 201 (21.9%) brains from foxes trapped in the Sachs Harbour area, but submissions from Cambridge Bay (127), Spence Bay (93) and Gjoa Haven (100) were negative. Virus was also present in salivary glands from 43 (97.7%) of these 44 positive foxes. The arctic fox continues to be the main wildlife reservoir of rabies in the Canadian Arctic and foxes in the prodromal stage of the disease pose a particular threat to the trapper. Preexposure vaccination should always be a consideration in this occupational group.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D005589:Foxes / Q000276:immunology / Q000382:microbiology*; D011818:Rabies / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D011820:Rabies virus / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral