Creatine kinase isoenzyme patterns in normal smooth muscle and smooth muscle neoplasms.
The CK isoenzyme composition of leiomyoma tissue is predominantly CK-BB and similar to adjacent myometrium tissue, while the leiomyosarcoma revealed a lesser quantity of CK-BB, but a greater quantity of CK-MM. The reasons for the discrepancy between the two types of neoplasms is not clear, but may reflect the changes which occur when smooth muscle becomes malignant.
D000842:Ankle; D002852:Chromatography, Ion Exchange; D003402:Creatine Kinase / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007889:Leiomyoma / Q000201:enzymology*; D007890:Leiomyosarcoma / Q000201:enzymology*; D009130:Muscle, Smooth / Q000201:enzymology*; D009215:Myometrium / Q000201:enzymology; D014594:Uterine Neoplasms / Q000201:enzymology*
D007527:Isoenzymes; D003402:Creatine Kinase