Change of urinary excretion of electrolytes after acid, base and furosemide application in sponge kidney.
Sponge kidney is rare clinical and pathological entity, incidentally found in 0.4--1% of all excretory urographies. In the advanced stage of the disease, distal tubules are affected and renal-tubular acidosis, change of urinary laminar flow and Ca2+ wasting syndrome result in frequent formation of Ca-oxalate stones. Alkali therapy is investigated on the excretion of Na+, K+ and Ca2+ and compared to furosemide administration.
D000141:Acidosis, Renal Tubular / Q000188:drug therapy; D000468:Alkalies / Q000627:therapeutic use*; D002118:Calcium / Q000378:metabolism; D004573:Electrolytes / Q000652:urine*; D005665:Furosemide / Q000627:therapeutic use*; D006801:Humans; D007691:Medullary Sponge Kidney / Q000188:drug therapy / Q000652:urine*
D000468:Alkalies; D004573:Electrolytes; D005665:Furosemide; D002118:Calcium