Effect of topical applications of heavy suspensions of killed Malassezia ovalis on rabbit skin.
Heavy applications of suspensions of killed Malassezia ovalis on rabbit skin produced lesions that both grossly and microscopically resembled human psoriasis. This system may afford not only a model but also an explanation for that disease.
D000818:Animals; D003170:Complement Pathway, Alternative; D004195:Disease Models, Animal; D005260:Female; D008290:Malassezia / Q000276:immunology / Q000472:pathogenicity*; D009504:Neutrophils; D011565:Psoriasis / Q000209:etiology* / Q000473:pathology; D011817:Rabbits; D012867:Skin / Q000473:pathology