title: Effects of ascorbic acid, vitamin E, and fatty acids on lipid composition in cockerels.
abstract: Serum, aorta, heart, and liver tissues of cockerels reflected numerous changes in cholesterol and triglyceride composition when 5 or 10% oleic or palmitic acid, ascorbic acid, and vitamin E were added to their diets. Heart cholesterol concentration and liver cholesteryl ester content increased with the 10% oleic acid diet. Heart and liver cholesterol increased when ascorbic acid was added to 5% fatty acid diets, and heart cholesterol increased when ascorbic acid was added to the 10% palmitic acid diet. Vitamin E exerted a cholesterol- or cholesteryl ester-lowering effect on both 10% palmitic and 10% oleic acid diets. Heart and liver triglycerides were lower with the 5% oleic acid diet than with the 5% palmitic acid diet. The opposite effect was observed with the 10% fatty acid diet. Dietary ascorbic acid appeared to have some triglyceride-lowering effect. Dietary fatty acid composition was reflected in cockerel aorta, heart, liver, and serum fatty acid distribution, with oleic acid having the greater influence.
mesh_terms: D000818:Animals; D001011:Aorta / Q000378:metabolism; D001205:Ascorbic Acid / Q000494:pharmacology*; D002645:Chickens / Q000378:metabolism*; D008055:Lipids / Q000032:analysis*; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009829:Oleic Acids / Q000494:pharmacology*; D010169:Palmitic Acids / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D008055:Lipids; D009829:Oleic Acids; D010169:Palmitic Acids; D014810:Vitamin E; D001205:Ascorbic Acid