Cerebral water and electrolytes in experimental ischaemia following omental transposition to the brain.
Occlusion of the middle cerebral artery induces a local decrease in percentage of tissue dry weight in rabbit brain, associated with flux of sodium and potassium in reciprocal directions. Cortical swelling occurs also in remote non-ischaemic areas. Previous transposition of the omentum majus to the brain minimizes the onset of oedema consequent on occlusion of a major cerebral artery. Increasing experimental evidence points to the role of omental transposition in providing an effective source of collateral circulation, thus strongly affecting the threshold for infarction.
D000818:Animals; D001834:Body Water / Q000032:analysis*; D001923:Brain Chemistry; D002545:Brain Ischemia / Q000628:therapy*; D002544:Cerebral Infarction / Q000517:prevention & control; D003097:Collateral Circulation; D009852:Omentum / Q000637:transplantation*; D011188:Potassium / Q000032:analysis*; D011817:Rabbits; D012964:Sodium / Q000032:analysis*; D014182:Transplantation, Autologous
D012964:Sodium; D011188:Potassium