[Treatment of acute pelvic inflammatory diseases with a new antibiotic compound preparation (author's transl)].
48 patients with acute pelvic inflammatory diseases (35 cases of acute adnexitis and 13 cases of inflammatory adnexal tumours) were treated with an antibiotic combination of Ampicillin/Oxacillin and Sisomicin. As initial parenteral therapy Ampicillin/Oxacillin 3.0 g was given intravenously twice daily and additionally Sisomicin 75 or 100 mg according to the body-weight was administered intramuscular twice daily. If required a further oral treatment with 500 mg Ampicillin/Dicloxacillin capsules four times a day was carried out. The average duration of parenteral treatment was 6.3 days; together with the oral treatment the duration of antibiotic treatment was 18.5 days. In 43 patients (89.6%) the disease could be cured completely or a distinct improvement could be achieved. Only in 5 cases (10.4%) the results were unsatisfactory. As side-effects allergic reactions were observed in three cases and gastro-enteritis in one case.
D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use*; D002582:Cervix Mucus / Q000382:microbiology; D004009:Dicloxacillin / Q000627:therapeutic use; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010068:Oxacillin / Q000627:therapeutic use*; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use; D012853:Sisomicin / Q000627:therapeutic use*
D004338:Drug Combinations; D005839:Gentamicins; D000667:Ampicillin; D011239:Prednisolone; D004009:Dicloxacillin; D010068:Oxacillin; D012853:Sisomicin
Die Behandlung akuter entzündungen im Bereiche der Adnexe mit einer neuen Antibiotikakombination.