title: A re-assessment of the efficacy of febantel (Rintal) and fenbendazole (Panacur) against Strongyloides papillosus in sheep and goats.
abstract: An efficacy evaluation using febantel and fenbendazole was carried out against Strongyloides papillosus in sheep and goats in the Grootfontein area of South West Africa/Namibia. Three groups with five sheep and three goats in each group were artificially infested with this species. When the worms had reached the adult stage one group was treated with febantel, the other group with fenbendazole and the third group left as controls. Both anthelmintics were dosed at 5 mg/kg. All animals were sacrificed one week after treatment and total worm-counts carried out. Both anthelmintics were found to be highly effective.
mesh_terms: D000083:Acetanilides / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage*; D001562:Benzimidazoles / Q000008:administration & dosage*; D004353:Drug Evaluation, Preclinical; D005260:Female; D005273:Fenbendazole / Q000008:administration & dosage*; D006041:Goats / Q000469:parasitology*; D006146:Guanidines / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D012756:Sheep / Q000469:parasitology*; D013321:Strongyloides / Q000187:drug effects*; D013322:Strongyloidiasis / Q000188:drug therapy
chemical_list: D000083:Acetanilides; D000871:Anthelmintics; D001562:Benzimidazoles; D006146:Guanidines; D005273:Fenbendazole; C017309:febantel