A study of the procoagulant properties of amniotic fluid and their correlation with the lecithin/sphingomyelin ratio.
The procoagulant properties of amniotic fluid have been studied in samples taken throughout pregnancy and the results correlated with the lecithin/sphingomyelin ratio: acceleration effects on the prothrombin time. Russell's viper venom test, activated partial thromboplastin time and specific factor VII and X assays and contact acceleration. Although amniotic fluid is shown to function as a complete thromboplastin and to activate factor X directly, none of these tests of procoagulant activity of amniotic fluid is a reliable index of fetal lung maturity.
D000653:Amniotic Fluid / Q000032:analysis / Q000502:physiology*; D001777:Blood Coagulation; D005167:Factor VII / Q000032:analysis; D005170:Factor X / Q000032:analysis; D005260:Female; D006801:Humans; D008168:Lung / Q000196:embryology; D010314:Partial Thromboplastin Time; D010713:Phosphatidylcholines / Q000032:analysis*; D011247:Pregnancy; D011517:Prothrombin Time; D013109:Sphingomyelins / Q000032:analysis*
D010713:Phosphatidylcholines; D013109:Sphingomyelins; D005167:Factor VII; D005170:Factor X