[Hemolytic action of lead in in vitro experiments].
The effect of some oxidizers and antioxidants on hemolytic action of lead has been studied in in vitro experiments performed with guinea-pig red cells. It has been shown that oxygen and hydrogen peroxide enhance the hemolysis while antioxidants prevent the hemolytic action of lead ions. This suggests the oxidative mechanism of the lead-induced hemolysis.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects; D006168:Guinea Pigs; D006461:Hemolysis / Q000187:drug effects*; D006861:Hydrogen Peroxide / Q000494:pharmacology; D066298:In Vitro Techniques; D007854:Lead / Q000494:pharmacology*; D010100:Oxygen / Q000494:pharmacology; D010313:Partial Pressure
D000975:Antioxidants; D007854:Lead; D006861:Hydrogen Peroxide; D010100:Oxygen
Gemoliticheskoe deĭstvie svintsa v opytakh in vitro.