title: Hypoplasia of the iris stroma in Gregg's syndrome unaccompanied by cataract but with deafness, rubella retinopathy and onset of glaucoma in adult or adolescent life.
abstract: Four patients with Gregg's syndrome (congenital rubella) are described. They were all deaf mutes but with clear lenses and good vision though they had marked hypoplasia of the iris stroma and rubella retinopathy. Three of the four had a high rise in intra ocular pressure which was destructive of vision and difficult to control, this was usually associated with a fine meshwork of tissue in the angle running from the front of the iris to the trabecular mesh. It is important that Ophthalmologists are aware of this condition which may be commoner than this series suggests.
mesh_terms: D000015:Abnormalities, Multiple / Q000150:complications*; D000293:Adolescent; D000328:Adult; D005260:Female; D005901:Glaucoma / Q000209:etiology*; D006801:Humans; D007498:Iris / Q000002:abnormalities*; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012164:Retinal Diseases / Q000209:etiology; D012409:Rubella / Q000151:congenital; D013577:Syndrome