title: Premature gonadal failure.
abstract: Fifty patients with premature gonadal failure were subdivided into primary and secondary failure groups. Karyotyping in the primary and ovarian histological examination in the secondary group are preferred diagnostic procedures. Several rare clinical syndromes are mentioned. Possible aetiological factors are identified, and a plea is made for the accurate diagnosis of this condition. Diagnostic pitfalls are also presented.
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology*; D005260:Female; D006059:Gonadal Dysgenesis / Q000150:complications*; D006801:Humans; D010049:Ovarian Diseases / Q000150:complications* / Q000473:pathology; D010053:Ovary / Q000473:pathology; D013997:Time Factors