Cucumis trigonus Roxb. II. Diuretic activity.
An alcoholic extract of Cucumis trigonus was studied for its diuretic activity in albino rats using hydrochlorothiazide as a standard drug for comparison. The extract exhibited a dose-dependent saliuretic effect reaching a peak at 4 hours. Unlike hydrochlorothiazide, the extract does not affect potassium excretion.
D000818:Animals; D002712:Chlorides / Q000652:urine; D028462:Cucumis; D004232:Diuretics; D005260:Female; D006852:Hydrochlorothiazide / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D011188:Potassium / Q000652:urine; D051381:Rats; D012964:Sodium / Q000652:urine
D002712:Chlorides; C028646:Cucumis trigonus extract; D004232:Diuretics; D010936:Plant Extracts; D006852:Hydrochlorothiazide; D012964:Sodium; D011188:Potassium