Effects of vasoactive intestinal polypeptide on resistance and capacitance vessels in the nasal mucosa.
Vasoactive intestinal polypeptide (VIP) immunoreactive nerves have previously been demonstrated in the feline nasal mucosa. In the present investigation it is shown that VIP given close arterially dilates both resistance and capacitance vessels in the nose of the cat. This vasodilatation is atropine resistant. It is suggested that VIP serves a physiological role in the neurogenic control of blood vessels in the nasal mucosa.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D005768:Gastrointestinal Hormones / Q000494:pharmacology*; D009297:Nasal Mucosa / Q000098:blood supply*; D012039:Regional Blood Flow / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology*; D014664:Vasodilation / Q000187:drug effects*
D005768:Gastrointestinal Hormones; D014660:Vasoactive Intestinal Peptide