Reduced lectin binding on erythrocytes of monkeys infected with malaria.
The number of binding sites for Axinella lectin (specific for D-galactose) on monkey erythrocytes containing schizonts of Plasmodium knowlesi was found to be reduced by about a third, from approximately 11 X 10(6) sites on normal erythrocytes to approximately 8 X 10(6) sites on parasitized erythrocytes. In contrast, only minor differences were found in the amounts of iodinatable external proteins. The results indicate that there is a general reduction of accessible sugars to which lectins may bind on parasitized erythrocytes.
D000818:Animals; D001665:Binding Sites; D004910:Erythrocyte Membrane / Q000378:metabolism* / Q000469:parasitology; D004912:Erythrocytes / Q000378:metabolism*; D037102:Lectins; D008253:Macaca mulatta; D008288:Malaria / Q000097:blood* / Q000469:parasitology; D008565:Membrane Proteins / Q000097:blood
D037102:Lectins; D008565:Membrane Proteins