Remarks about some pharmacopoieal safety tests for plastics and elastomers.
A survey of the biological methods for quality control of plastics and elastomers included in pharmacopoeias is given. The value of some of these methods (test for pyrogen-like substances, test for acute systemic toxicity in mice, tests on frog hearts, on Daphnia magna and on rat sperm, mode of extraction) is discussed.
D000818:Animals; D001001:Anura; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005859:Germany, East; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D007509:Irritants; D051379:Mice; D010602:Pharmacopoeias as Topic; D010969:Plastics / Q000592:standards* / Q000633:toxicity; D011749:Pyrogens / Q000633:toxicity; D011786:Quality Control; D051381:Rats; D012408:Rubber / Q000592:standards* / Q000633:toxicity; D012449:Safety; D012867:Skin / Q000187:drug effects
D007509:Irritants; D010969:Plastics; D011749:Pyrogens; D012408:Rubber