title: [Metabolism of the methylotrophic yeasts Candida methylica].
abstract: The activity of the following enzymes was investigated in cell extracts of Candida methylica cultivated in media with methanol or glucose: the enzymes of glycolysis, the pentose phosphate pathway, the citric acid cycle and the glyoxylate shunt; pyruvate and phosphoenolpyruvate carboxylases; dehydrogenases of amino acids. Different activities of the enzymes suggest that metabolic pathways for these substrates are alternative and that methanol is assimilated by the yeast via the dihydroxyacetone pathway. A scheme for methanol metabolism in Candida methylica is proposed and discussed.
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D002175:Candida / Q000201:enzymology / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis; D006038:Glyoxylates / Q000378:metabolism; D000432:Methanol / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism; D010428:Pentosephosphates / Q000378:metabolism; D010730:Phosphoenolpyruvate Carboxylase / Q000378:metabolism; D011766:Pyruvate Carboxylase / Q000378:metabolism
chemical_list: D000596:Amino Acids; D006038:Glyoxylates; D010428:Pentosephosphates; D010088:Oxidoreductases; D010730:Phosphoenolpyruvate Carboxylase; D011766:Pyruvate Carboxylase; D005947:Glucose; D000432:Methanol
vernacular_title: Metabolizm metilotrofnykh drozhzheĭ Candida methylica.