title: Salt-induced conformational changes of poly(dA-dT).
abstract: Conformational changes of poly(dA-dT) . poly(dA-dT) induced by increasing ionic strength were studied using CD spectroscopy. It was found that a pronounced noncooperative inversion of the long-wavelength part of the CD spectrum of poly(dA-dT) . poly(dA-dT) occurred at high concentrations of CsF in solution. It was suggested that a great difference between the geometries of the purine and pyrimidine residues in the helix was characteristic of the structure of poly(dA-dT) . poly(dA-dT) in concentrated CsF solutions.
mesh_terms: D002586:Cesium; D002942:Circular Dichroism; D005459:Fluorides; D009690:Nucleic Acid Conformation; D009994:Osmolar Concentration; D011067:Poly dA-dT; D011089:Polydeoxyribonucleotides; D012492:Salts
chemical_list: D011089:Polydeoxyribonucleotides; D012492:Salts; D002586:Cesium; D011067:Poly dA-dT; D005459:Fluorides; C027754:cesium fluoride