Prenatal exposure to synthetic progestins increases potential for aggression in humans.
Seventeen females and eight males exposed during gestation to synthetic progestins showed a significantly higher potential for physical aggression than their sex-matched unexposed siblings. Exposure to androgen-based compounds appeared to be most closely associated with aggressive responses. There were no differences in verbal aggression or IQ between exposed and unexposed siblings.
D000293:Adolescent; D000374:Aggression / Q000187:drug effects*; D001519:Behavior / Q000187:drug effects*; D002648:Child; D004622:Embryo, Mammalian / Q000187:drug effects*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D008297:Male; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000494:pharmacology*
D045167:Progesterone Congeners