Ovine systemic pasteurellosis caused by Pasteurella haemolytica biotype T.
A detailed study was made of lambs aged 5--7 months naturally infected with Pasteurella haemolytica biotype T. In addition to the well known features of such infections, previously unreported necrotic lesions of the tonsil, oesophagus, pharynx and adjacent areas were consistently seen. Large numbers of P. haemolytica were present in the tonsil, oesophageal lesions, lung, liver and spleen, but few or none in other tissues. The evidence indicated that the disease was not a true septicaemia. It is postulated that P. haemolytica biotype T already present in the tonsils multiplies and invades the adjacent tissues of the upper alimentary tract; groups of organisms from this site enter the blood stream as emboli, most of which lodge in the capillary beds of the lung and liver; rapid multiplication of organisms in these tissues leads to death from the effects of endotoxin.
D000818:Animals; D001921:Brain / Q000473:pathology; D010325:Pasteurella / Q000302:isolation & purification; D010326:Pasteurella Infections / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D010614:Pharynx / Q000473:pathology; D012703:Serotyping; D012756:Sheep; D012757:Sheep Diseases / Q000209:etiology* / Q000473:pathology