title: [Use of lithium carbonate to treat Kugelberg--Welander spinal amyotrophy].
abstract: On the basis of data on disturbances of the metabolism of cyclic 3',5'-adenosine monophosphate in patients with Kugelberg-Welander's amyotrophy it is suggested that lithium carbonate which is an inhibitor of adenylcyclase should be used as a medicine. It was shown that the drug exerted a stabilizing influence on the pathological process. Positive clinical and biochemical changes due to the application of lithium carbonate are noted.
mesh_terms: D000293:Adolescent; D000328:Adult; D002254:Carbonates / Q000627:therapeutic use; D002648:Child; D003401:Creatine / Q000652:urine; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D008094:Lithium / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009046:Motor Neurons; D009133:Muscular Atrophy / Q000188:drug therapy / Q000235:genetics* / Q000652:urine; D013118:Spinal Cord Diseases / Q000188:drug therapy / Q000235:genetics* / Q000652:urine; D013577:Syndrome
chemical_list: D002254:Carbonates; D008094:Lithium; D003404:Creatinine; D003401:Creatine
vernacular_title: Primenenie uglekislogo litiia dlia lecheniia spinal'noĭ amiotrofii Kugel'berga--Velandera.