Effects of testosterone on estracyt localization in rat prostate.
Testosterone administration to castrated rats leads to increased concentrations of radioactivity associated with estracyt (a conjugate of carbamate with E2) in the prostate gland, particularly the ventral prostate. This contracts with the decreased concentrations of labeled E2. The findings appear to shed further light on the possible mechanism of action of estracyt in cancer of the prostate.
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D004958:Estradiol / Q000378:metabolism; D004961:Estramustine / Q000032:analysis / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D009588:Nitrogen Mustard Compounds / Q000378:metabolism*; D011467:Prostate / Q000378:metabolism*; D051381:Rats; D013739:Testosterone / Q000494:pharmacology*
D009588:Nitrogen Mustard Compounds; D004961:Estramustine; D013739:Testosterone; D004958:Estradiol