4-methoxy-3-hydroxyphenylglycol as an internal standard for the determination of 3-methoxy-4-hydroxyphenyglycol in urine: results obtained in depressed patients and healthy controls.
A modification of the method developed by Dekirmenjian & Maas (1970) Anal. Biochem. 35, 113-122) is described for the determination of 3-methoxy-4-hydroxyphenylglycol in urine. The use of 4-methoxy-3-hydroxyphenylglycol as an internal standard improves the accuracy, simplicity and reproducibility. Therefore, the method is suitable for routine determination in laboratories without gas chromatography/mass spectrometry equipment. Some results obtained in depressed patients and healthy controls are presented.
D002849:Chromatography, Gas / Q000379:methods; D003863:Depression / Q000652:urine*; D005069:Evaluation Studies as Topic; D006018:Glycols / Q000652:urine*; D006801:Humans; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D012016:Reference Values
D006018:Glycols; D008734:Methoxyhydroxyphenylglycol