Creatine phosphokinase elevations and psychiatric symptomatology.
The authors retrospectively studied 322 patient-admissions to the ward service of a psychiatric hospital for the period of 1 year. Twenty-five acutely psychotic patients were found who had unexplained elevations of serum creatine phosphokinase (CPK); 14 of the 25, (56%) had either a research or a clinical diagnosis of primary affective disorder, bipolar type (mania). Similar findings of CPK elevations and acute psychosis by other authors are described.
D000293:Adolescent; D000328:Adult; D000341:Affective Disorders, Psychotic / Q000201:enzymology*; D001714:Bipolar Disorder / Q000201:enzymology; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012559:Schizophrenia / Q000201:enzymology*
D003402:Creatine Kinase