A specifically induced bronchoconstriction by distilled water in children and adults.
Respiratory function (FVC, FEV1, FMF and FEF200-1200) was measured before and after nebulized distilled water in 68 subjects divided in the five following groups: a) 21 healthy children (age range 7 to 15 years); b) 10 children with asthma (age range 6 to 11 years); c) 10 children with cystic fibrosis (age from 5 to 15 years); d) 7 children with different diseases of the respiratory system (age range from 6 to 11 years); e) 20 healthy adults (aged from 18 to 33 years). The only statistically significant changes were noted in the asthmatic children group. We conclude that a specifically induced bronchoconstriction by nebulized distilled water is a good mean of assessing bronchial lability.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000503:physiopathology; D001986:Bronchial Spasm / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000503:physiopathology; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008448:Maximal Expiratory Flow Rate; D012120:Respiration Disorders / Q000503:physiopathology; D012129:Respiratory Function Tests; D014867:Water
D014867:Water