Effect of detrusor muscle length and tension on its response to pharmacologic and electrical stimulation. Part II. In vitro study.
The effect of varying lengths and tension of guinea pig detrusor strips on their response to pharmacologic and electrical stimulation was investigated. Our findings demonstrated that changes in muscle tension and length did alter the magnitude of the response to each agent tested.
D000818:Animals; D004558:Electric Stimulation; D006168:Guinea Pigs; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D010277:Parasympathomimetics / Q000494:pharmacology*; D013566:Sympathomimetics / Q000494:pharmacology*; D001743:Urinary Bladder / Q000502:physiology
D010277:Parasympathomimetics; D013566:Sympathomimetics