title: [The influence of hypobaric hypoxia upon the hemodynamics of the pulmonary circulation (author's transl)].
abstract: The influence of hypobaric hypoxia at the pulmonary gaseous exchange and the hemodynamics of the pulmonary circulation was tested by 12 healthy subjects at the age from 33 to 47 years. They were submitted to a basis investigation with determination of VC, VE, VO2, VCO2, Hb, PO2A/a, pH, HR, ECG, PVd, PAp, HZV, RL. These investigations were followed by stress examination by means of the bicycle ergometry in four rectangular steps during conditions of normoxia and of hypobaric hypoxia in a low-pressure chambre at 66.5 kPa (500 Torr) each of 6 min duration. During the influence of hypoxia a PO2a-decrease in a sense of partial insufficiency could be already observed at rest during conditions of a decreased alveolar oxygen-partial-pressure. At the same time was found a significant increase of the systolic peripheral and the diastolic pulmonary arterial pressure. At the increasing step by step ergometric exercise during conditions of the hypoxia stress were growing significance evidence of different reactions of the pulmonary and cardiocirculatory parameters occurred.
mesh_terms: D000328:Adult; D001274:Atmospheric Pressure; D001794:Blood Pressure; D006439:Hemodynamics; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008875:Middle Aged; D005082:Physical Exertion; D011651:Pulmonary Artery; D011652:Pulmonary Circulation; D012119:Respiration
vernacular_title: Der Einfluss der hypobaren Hypoxie auf die Hämodynamik des kleinen Kreislaufes.