Persistent corneal erosion secondary to tarsal adrenochrome deposit.
A 64-year-old man with open-angle glaucoma had used topically applied epinephrine for 13 years. He developed a foreign-body sensation and persistent superotemporal corneal erosion as a result fo an adrenochrome deposit on the upper tarsus. Removal of the deposit ended the corneal erosion and returned visual acuity to normal.
D000323:Adrenochrome / Q000032:analysis*; D003320:Corneal Ulcer / Q000139:chemically induced / Q000209:etiology*; D004837:Epinephrine / Q000009:adverse effects* / Q000627:therapeutic use; D005141:Eyelid Diseases / Q000139:chemically induced / Q000209:etiology*; D005901:Glaucoma / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged
D000323:Adrenochrome; D004837:Epinephrine