title: Hepatitis B virus, sex ratio and the H-Y antigen.
abstract: The hypothesis that Hepatitis B surface Antigen (HBsAg) is cross-reactive with the male-specific H-Y antigen has been tested. In none of three separate experiments using selected anti-HBs sera, or in a fourth experiment using anti-H-Y sera, could any evidence for cross-reactivity be detected. Our results are therefore not compatible with the idea that altered sex-ratios observed among offspring of parents infected with Hepatitis B virus are related to cross-reactivity between HBsAg and a male-associated antigen.
mesh_terms: D000818:Animals; D003429:Cross Reactions; D005260:Female; D006168:Guinea Pigs; D006182:H-Y Antigen / Q000276:immunology*; D006509:Hepatitis B / Q000235:genetics; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008297:Male; D051381:Rats; D012744:Sex Ratio
chemical_list: D006182:H-Y Antigen; D006514:Hepatitis B Surface Antigens