title: [Role of the mastocytes during functional activation of the thyroid].
abstract: The behaviour of biogenic amines in mastocytes has been studied in the thyroid glands of rats treated with 2 U.I. of TSH. The histochemical evaluation of histamine and 5-HT in mastocytes with the method of fluorochromization has been carried out at 20 minutes and 120 minutes after TSH administration. After 20 minutes, the thyroid glands do not present evident parenchymal changes, but the positivity for biogenic amines in mastocytes decreases in comparison to the controls, while this positivity begins to be evident in the interstitial tissue. After 120 minutes, the thyroid gland shows a microfollicular arrangement and the fluorescent biogenic amines appear to be released in the interstitium by degranulating mastocytes, nearly entirely negative to fluorochromization.
mesh_terms: D000818:Animals; D006632:Histamine / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism*; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism; D013972:Thyrotropin / Q000494:pharmacology
chemical_list: D012701:Serotonin; D006632:Histamine; D013972:Thyrotropin
vernacular_title: Rôle des mastocytes au cours de l'activation fonctionnelle de la thyroïde.