[Immunostimulating and antitumor action of psychotropic preparations of the sydnonimine series].
In healthy animals and in those with different experimental tumours, the psychostimulant drug sydnophen activates the immune reactions: increases the number of RFC, the intensity of delayed hypersensitivity, blast transformation of lymphocytes, and the QD coefficient. This activation is attended by a slight inhibition of transplanted tumours. The psychostimulant sydnocarb exerts no immunostimulant action or any effect on the growth of experimental tumours.
D000276:Adjuvants, Immunologic; D000818:Animals; D000970:Antineoplastic Agents; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000188:drug therapy; D010069:Oxadiazoles / Q000276:immunology*; D011619:Psychotropic Drugs; D011817:Rabbits; D012397:Rosette Formation; D013558:Sydnones / Q000276:immunology*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D010069:Oxadiazoles; D011619:Psychotropic Drugs; D013558:Sydnones; C013271:sydnophen; C009257:sidnocarb
Ob immunostiomuliruiushchem i protivoopukholevom deĭstvii nekotorykh psikhotropnykh preparatov sidnoniminovogo riada.