[Effect of circulating insulin on liver damage by CCl4 in the rat. II. Histological aspects].
The authors have studied the damaging effects of CCl4 (0.05ml/Kg) in healthy rats, in alloxan diabetic rats and in rats treated with tolbutamide per os (100mg/Kg) for twenty days. Histological studies in these animals demonstrated that actually hyperinsulinemia has a slight protective action on damage produced by CCl4 on rat liver.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000473:pathology*; D003921:Diabetes Mellitus, Experimental / Q000473:pathology*; D006946:Hyperinsulinism / Q000139:chemically induced / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D051381:Rats; D014044:Tolbutamide
D014044:Tolbutamide
Effetti dell'insulina circolante sull'azione epatolesiva da CCl4 nel ratto. II. Aspetti istologici.