Effects of intestinal obstruction of plasma water and extracellular fluid volumes in the rat.
Total and regional plasma water and extracellular fluid volumes were measured in rats after obstruction of the small intestine. The rats lost 12.6 per cent of their initial weight. The volume of the sequestrated fluid in the obstructed intestine corresponded to 91 per cent of the plasma water volume. Intestinal obstruction caused a 19 per cent reduction of the total plasma water volume, while the total extracellular fluid volume was unchanged. Regional extracellular fluid volumes were diminished in the lung, liver and gastric antrum and increased in omental fat. The results indicate regional differences in fluid space responses to obstruction of the small intestine.
D000818:Animals; D001769:Blood; D001835:Body Weight; D005110:Extracellular Space; D006400:Hematocrit; D007415:Intestinal Obstruction / Q000150:complications* / Q000378:metabolism; D008297:Male; D051381:Rats; D014883:Water-Electrolyte Imbalance / Q000209:etiology* / Q000378:metabolism