title: Renal osteodystrophy. Effect of hemodialysis and 1 alpha-hydroxy vitamin D3 on bone lesions and metacarpal bone mass.
abstract: Radiologic bone lesions in 20 long-term hemodialyzed patients with chronic renal failure are described. During chronic dialysis the bone lesions increased. Treatment of 8 patients with 1 alpha-OH-D3 for 6 months prevented progression of the bone lesions or improved them.
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000187:drug effects / Q000473:pathology*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000473:pathology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008297:Male; D008663:Metacarpus / Q000473:pathology; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D006887:Hydroxycholecalciferols; C008088:alfacalcidol