title: Liver toxicity of diatrizoate and a non-ionic contrast medium (C29). Coeliac angiography in the rabbit.
abstract: Toxic effect on the liver of diatrizoate and a new non-ionic contrast medium (C29) were investigated using coeliac angiography in rabbits. The contrast media were injected in doses of 5 ml/kg rabbit with a concentration of 370 mg I/ml. Serum levels of ALAT, ASAT, ALP and bilirubin did not change significantly after the injections.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D002445:Celiac Artery / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000633:toxicity*; D003973:Diatrizoate / Q000633:toxicity*; D007463:Iodobenzoates / Q000633:toxicity*; D007479:Iopamidol / Q000031:analogs & derivatives*; D008075:Lipoproteins, HDL / Q000097:blood; D008099:Liver / Q000187:drug effects*; D008297:Male; D008793:Metrizamide / Q000633:toxicity; D011817:Rabbits; D011859:Radiography; D014283:Triiodobenzoic Acids / Q000633:toxicity*
chemical_list: D003287:Contrast Media; D007463:Iodobenzoates; D008075:Lipoproteins, HDL; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; C020687:C 29 (contrast media); D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D007479:Iopamidol; D001663:Bilirubin; D008793:Metrizamide