Pair-feeding in the dietary control of glucose-6-phosphate dehydrogenase.
The great increase ("overshoot") in glucose-6-phosphate dehydrogenase activity in liver cytoplasm which follows the transfer of rats from starvation to a high sucrose diet has been recognized for a number of years. Also the fact that transferring fed rats to the high sucrose diet results only in a small increase in G6PD activity while transfer of "starved" rats to the high sucrose diet results in a 10 to 20-fold ("overshoot") increase in G6PD activity is equally recognized. This report demonstrates that the "overshoot" following 4 days without food is not due to an increase in food intake compared to the food intake of fed rats since pair-feeding during this refeeding at three different levels does not eliminate the effect of the prior fast.
D000818:Animals; D001835:Body Weight; D003593:Cytoplasm / Q000201:enzymology; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D005502:Food; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000033:anatomy & histology / Q000201:enzymology*; D009929:Organ Size; D051381:Rats; D013217:Starvation / Q000201:enzymology*; D013395:Sucrose / Q000008:administration & dosage
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D013395:Sucrose; D005954:Glucosephosphate Dehydrogenase