Relationship between EEG sleep patterns and clinical improvement in depressed patients treated with sleep deprivation.
The effects of a single night of total sleep deprivation were observed in 16 primary depressed patients. Responders to treatment were rated as significantly more depressed and revealed a more "depressed" EEG sleep pattern prior to sleep deprivation than did nonresponders. Following sleep deprivation, patients who improved experienced a rebound in REM sleep during the second night of recovery sleep.
D000328:Adult; D000704:Analysis of Variance; D003866:Depressive Disorder / Q000503:physiopathology / Q000628:therapy*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012892:Sleep Deprivation; D012894:Sleep Stages / Q000502:physiology