Improvement of the correlation of bacterial mutagenicity with carcinogenicity of benzo(a)pyrene and four of its major metabolites by activation with intact liver cells instead of cell homogenate.
D000818:Animals; D001580:Benzopyrenes; D001711:Biotransformation; D002273:Carcinogens; D002474:Cell-Free System; D004851:Epoxide Hydrolases / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008298:Maleates / Q000494:pharmacology; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests / Q000379:methods*; D009153:Mutagens; D051381:Rats; D012457:Salicylamides / Q000494:pharmacology
D001580:Benzopyrenes; D002273:Carcinogens; D008298:Maleates; D009153:Mutagens; D012457:Salicylamides; D004851:Epoxide Hydrolases; C014476:diethyl maleate