title: [Systemic side effects of topically applied corticosteroid medication (author's transl)].
abstract: Eye drops and ointments containing corticosteroids moderately influence plasma cortisol levels. Subconjunctival or retrobulbar injections of dexamethasone phosphate (4 mg/day) have a pronounced effect on endogenous cortisol synthesis. This effect, however, is reversible. If additional oral corticosteroid medication is given over a prolonged period of time the function of the adrenal glands may be seriously damaged for more than a year.
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D011239:Prednisolone; D014605:Uveitis / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; D011239:Prednisolone; D006854:Hydrocortisone
vernacular_title: Der Einfluss okulär applizierter Glukokortikoide auf die Nebennierenrindenfunktion.