Immunoglobulin-stimulated superacidity in duodenal ulcer.
It is suggested on the ground of the present study that in a number of cases of duodenal ulcer it is an immunoglobulin of the class IgG which, as a stimulating factor, accounts for overproduction of gastric HCl. This immunoglobulin takes effect by direct attachment to the parietal cells.
D000818:Animals; D004381:Duodenal Ulcer / Q000276:immunology* / Q000503:physiopathology; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000187:drug effects / Q000276:immunology*; D005755:Gastrins / Q000378:metabolism; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D008211:Lymphocyte Cooperation; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects
D005755:Gastrins; D007074:Immunoglobulin G