title: Evidence for the participation of a 5-oxo-prolinase in degradation of glutathione in Nicotiana tabacum.
abstract: During degradation of glutathione in tobacco suspension cultures substancial amounts of 5-oxo-proline are formed in vivo as well as in crude cell homogenates in vitro. The existance of a 5-oxo-prolinase that catalyzes the conversion of 5-oxo-proline to glutamic acid was demonstrated in tobacco cells, grown with glutathione as sole sulfur source.
mesh_terms: D000581:Amidohydrolases / Q000378:metabolism*; D002478:Cells, Cultured; D005978:Glutathione / Q000378:metabolism*; D007700:Kinetics; D010944:Plants / Q000201:enzymology*; D010947:Plants, Toxic; D011752:Pyroglutamate Hydrolase / Q000378:metabolism*; D014026:Nicotiana / Q000201:enzymology
chemical_list: D000581:Amidohydrolases; D011752:Pyroglutamate Hydrolase; D005978:Glutathione