title: [Pharmacological and toxicological investigation of 2,2-diethyl-2,3,5,10-tetrahydro-1H-pyrazolo(1,2-b)phthalazine-1,3-dione, a new compound with anti-inflammatory activity].
abstract: As part of research on 1H-pyrazole[1,2-b]phthalazine compounds with anti-inflammatory activity, the results of preliminary pharmacological and toxicological investigation of 2,2-diethyl-2,2,5,10-tetrahydro-1H-pyrazolo[1,2-b]phthalazine-1,3-dione are reported.
mesh_terms: D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000633:toxicity; D001463:Barbiturates / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002351:Carrageenan; D004487:Edema / Q000503:physiopathology; D005260:Female; D006097:Granulation Tissue / Q000187:drug effects; D051379:Mice; D010793:Phthalazines / Q000494:pharmacology* / Q000633:toxicity; D011724:Pyridazines / Q000494:pharmacology*; D051381:Rats; D012890:Sleep / Q000187:drug effects; D013997:Time Factors
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D001463:Barbiturates; D010793:Phthalazines; D011724:Pyridazines; C028081:2,2-diethyl-2,3,5,10-tetrahydro-1H-pyrazolo(1,2-b)phthalazine-1,3-dione; D002351:Carrageenan
vernacular_title: Indagine farmacotossicologica sul 2,2-dietil-2,3,5,10-tetraidro-1H-pirazolo[1,2-b]ftalazin-1,3-dione nuovo composto ad attività antinfiammatoria.