Noradrenaline and dopamine levels in acute cerveau isolé in the cat.
Noradrenaline (NA) and dopamine (DA) levels were studied in the forebrain of acute immobilized  cats and in cerveau isolé preparations. A gradual decrease in NA and DA was observed one and two hours after high mesencephalic transection, while the amount of NA increased in acute immobilized cats after the cessation of ether anaesthesia. These changes in NA level are consistent with the observations suggesting an inverse relationship between NA and cortical deactivation. The decrease of DA with an exaggeration of spindle activity and increased synchronizing effect of basal forebrain stimulation indicate that the spindle-increasing effect of DA suggested by several authors requires the contribution of the brain stem.
D000818:Animals; D001834:Body Water / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D002415:Cats; D003655:Decerebrate State / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D013997:Time Factors
D004298:Dopamine; D009638:Norepinephrine