Prednisolone concentrations in plasma, saliva and urine.
Prednisolone was measured in plasma, saliva and urine at various times after a single dose. Peak plasma prednisolone levels were observed about 1 h after the dose. Saliva prednisolone levels were measurable for at least 3 h after dosing but showed no consistent relationship to either total or free plasma prednisolone concentrations. Unchanged prednisolone in amounts up to 14% of the dose administered was found in the 24 h urine and most of it was excreted in the first 5 h.
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000032:analysis* / Q000097:blood / Q000378:metabolism / Q000652:urine; D011863:Radioimmunoassay; D012463:Saliva / Q000032:analysis*
D011239:Prednisolone