Changes in plasma folate levels in rats inhaling nitrous oxide.
Inhalation of nitrous oxide, which inactivates vitamin B12, is followed by a rise in the plasma folate level. The concentration of plasma folate remains elevated throughout the period of exposure to nitrous oxide. Returning the rats to the air is followed by a fall to pre-exposure plasma folate levels within 24 h.
D000818:Animals; D005492:Folic Acid / Q000031:analogs & derivatives / Q000097:blood*; D009609:Nitrous Oxide / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D014805:Vitamin B 12 / Q000494:pharmacology
D005492:Folic Acid; D009609:Nitrous Oxide; D014805:Vitamin B 12