title: [Morphological studies on the problem of cholestasis due to cardiac insufficiency and its relationship to parenchymal necroses of the liver].
abstract: For the differentiation of the disturbances of the uric acid metabolism the determination of the uric acid clearance is a valuable help. A normal clearance (greater than or equal to 0.116 ml/s, 7 ml/min) in hyperuricaemia speaks for an overproduction of uric acid (type I), a decreased clearance (less than or equal to 0.100 ml/min) speaks for a disturbance of the renal excretion (type II). By additional parameters which are simply to be got further subtypes (Ia, Ib, IIa, IIb, III) can be delimited. All examinations can be performed under ambulatory conditions. On the basis of this division the antihyperuricaemics may be better used. The application of the drugs according to types favours the decrease of the side-effects of the drugs and additionally shows economic advantages.
mesh_terms: D002779:Cholestasis / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000209:etiology*; D009203:Myocardial Infarction / Q000150:complications* / Q000473:pathology; D009336:Necrosis; D011655:Pulmonary Embolism / Q000150:complications / Q000473:pathology
vernacular_title: Morphologische Untersuchungen zum Problem der kardial bedingten Cholestase und ihrer Beziehungen zu Parenchymnekrosen der Leber.