[The translation of the program-information about the protein-synthesis in the liver in chronic liver diseases (author's transl)].
Specimens of liver biopsies from 25 patients with chronic liver diseases were examined by electron microscopy using the method of Bernhard with EDTA. In cases with liver cirrhosis an increase of the perichromatin-granula within the nucleus of the hepatocytes was found. During the entrance from the nucleus into the cytoplasma the granula often changed into granulofibrin structures, representing a complex of macromolecular ribonucleoproteins, the carrier of the information-RNS of the nucleus.
D002467:Cell Nucleus / Q000378:metabolism; D002908:Chronic Disease; D006801:Humans; D008107:Liver Diseases / Q000378:metabolism* / Q000473:pathology; D014176:Protein Biosynthesis
Kernphase der Ubertragung von Programminformationen über die Proteinsynthese in der Leber bei chronischen Lebererkrankungen.