[Neurological complications of hemophilia in children (author's transl)].
Although the treatment of hemophilia has greatly improved, the disease is still sometimes responsible for neurological or neurosurgical disorders. Such disorders were observed in the department of Neurosurgery at the "Hopital des ENFANTS MALADES' in twelve hemophiliacs, five of them having antifactor antibodies. Four main points results from this study: 1) A traumatic etiology was found only in one third of the cases. 2) CT Scan is the main investigation since it allows to find out what cases should be operated upon. The ratio of neurosurgical cases varies from one statistic to another from 40% to 70%. 3) The frequency of neurological disorders is correlated with the importance of the deficit in antihemophilic factors, which is usually less than 1%. 4) The death rate in this series was nil. Hemophiliacs without antifactor antibodies should receive a substitutive treatment as soon as possible. However, in hemophiliacs with antifactor antibodies, this treatment should only be given when surgery is required.
D001927:Brain Diseases / Q000209:etiology / Q000628:therapy; D002648:Child; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D009422:Nervous System Diseases / Q000209:etiology* / Q000628:therapy
Les accidents neurologiques de l'hémophilie chez l'enfant.