[Variations in the resting membrane potential of denervated and tenotomized-denervated rat skeletal muscles].
Resting membrane potential (RMP) was studied in denervated (D), tenotomized (T) and tenotomized-denervated (TD) Soleus (S) and Tibialis Anterior (TA) muscles of the rat. In TD muscles, denervation was performed 1 week after tenotomy. The measurements were performed "in vitro" at 20 degrees C, 1-7 days after denervation in D and TD muscles, and 7 days after tenotomy in T muscles. In T muscles there were not differences in comparison with the controls. In D muscles RMP decreased earlier in S than in TA. The time course of membrane depolarization was similar in TD and D muscles until the 2nd day after denervation. At the 3rd day, RMP showed a further, significant reduction in TD muscles, both in S and TA, but not in D muscles. In D muscles, the depolarization increased very slowly up to the 7th day.
D000818:Animals; D007866:Leg; D008564:Membrane Potentials; D009121:Muscle Denervation; D009132:Muscles / Q000502:physiology*; D009928:Organ Specificity; D051381:Rats; D013710:Tendons / Q000601:surgery; D013997:Time Factors
Variazioni del potenziale di membrana a riposo in muscoli scheletrici denervati e tenotomizzati-denervati di ratto.