A test of the hypothesis that time to tumor in humans fits the "one-hit" model.
Data from the Connecticut Tumor Registry for 1935-1968 for 14 tumor sites were subjected to formal statistical tests of the hypothesis that the time to tumor has an exponential distribution (and hence is a result of one random "hit"). All of the resulting 270 test statistics rejected the hypothesis.
D000367:Age Factors; D003237:Connecticut; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000453:epidemiology*; D012042:Registries; D013997:Time Factors