title: Is lithium mutagenic in man?
abstract: Peripheral blood lymphocytes of 77 patients under lithium-therapy were analyzed with respect to structural chromosomal aberrations. As compared to controls not treated with lithium, no elevation of the frequencies of chromosomal aberrations was found in the patients. Comparable investigations may lead to erroneous conclusions if the higher X-ray load of psychiatric patients is not considered.
mesh_terms: D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008094:Lithium / Q000009:adverse effects*; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009152:Mutagenicity Tests; D009153:Mutagens
chemical_list: D009153:Mutagens; D008094:Lithium