[Relationship between epidemiology of cancer and experimental carcinogenesis].
Scientific criteria for the recognition of carcinogenicity for man of specific chemicals and mixtures are described with examples. Cohort, and to a lesser extent case-control studies may lead to the demonstration of the carcinogenicity of a specific chemical. However, this requires several conditions which are not easy to meet. This might explain the low number of chemicals recognized as carcinogenic for the human species. Therefore, the prediction of carcinogenic risks of a chemical to man often relies only on the experimental evidence of presence or absence of long-term effects.
D000818:Animals; D002273:Carcinogens; D006801:Humans; D009369:Neoplasms / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced
D002273:Carcinogens
Interazioni tra epidemiologia dei tukmori e cancerogenesi sperimentale.