[Ruptured intracranial saccular aneurysm. Conduct to apply before direct surgical intervention (stabilization of arterial pressure with diazepam].
The 250 patients of this series, whatsoever was the location of the aneurysm, were operated radically on the 6th and 7th day following the rupture. That is to say at the end of the brain swelling period and before the rebleeding period. During these 5 or 6 days the blood pressure was stabilized by a daily intake of diazepam (15 to 30 millig); 10% only of the patients were resistant; in these cases clonidine was used. During this period antifibrinolitic agents were not given as well as antioedematous therapy. No case of rebleeding was observed in this series under this therapy.
D001794:Blood Pressure / Q000187:drug effects; D003975:Diazepam / Q000627:therapeutic use*; D006801:Humans; D002532:Intracranial Aneurysm / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D011300:Preoperative Care; D012422:Rupture, Spontaneous; D013997:Time Factors
D003975:Diazepam
Anévrysme sacculaire intra-crânien rompu. Conduite à tenir durant la période précédent l'abord direct (stabilisation de la pression artérielle par le diazépam).