title: Local treatment of neoplastic pleural effusions.
abstract: Efficacy of local treatment of neoplastic pleural effusions may be related to the administered drugs, as judged by our series of 225 patients. The evaluation of the local improvement--which did not interfere with the evolution of the primary cancer--showed good (45.9%) or satisfactory (48.6%) results in a series of 148 patients treated with peptichemio. This local improvement was practically devoid of any adverse side-effect even when the treatment was particularly prolonged. This survey deals with 15 years of therapeutical experience concerned with neoplastic pleural effusions from malignant epithelial tumours.
mesh_terms: D004305:Dose-Response Relationship, Drug; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008558:Melphalan / Q000031:analogs & derivatives*; D010440:Peptichemio / Q000627:therapeutic use*; D010587:Phagocytosis / Q000187:drug effects; D010996:Pleural Effusion / Q000188:drug therapy*
chemical_list: D010440:Peptichemio; D008558:Melphalan