title: Termination of pregnancy in patients with missed abortion and intrauterine dead fetuses by a single intracervical application of prostaglandin E2 in viscous gel.
abstract: To terminate pregnancy 15 women with an established diagnosis of missed abortion or intrauterine dead fetuses were treated with 1.0 mg Prostaglandin E 2 in viscous gel applied as a single intracervical dose. -- Abortion was induced after a mean of 7.0 hours in 8 patients with a mean gestational age of 15.0 weeks, and a subsequent evacuation of the uterine cavity was easily performed. -- Complete abortion/delivery was obtained in 7 patients with a gestational age of 33 weeks. The over-all mean induction/delivery time was 7.5 hours. -- Apart from pain related to uterine contractions no side effects were observed and no complications occurred. It is concluded that the present technique represents a promising alternative in the treatment of patients with missed abortion or intrauterine dead fetuses.
mesh_terms: D000030:Abortion, Missed / Q000628:therapy*; D000032:Abortion, Therapeutic / Q000379:methods*; D000328:Adult; D002584:Cervix Uteri; D005260:Female; D005313:Fetal Death; D005782:Gels; D006801:Humans; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage*
chemical_list: D005782:Gels; D011458:Prostaglandins E