Effect of chlorhexidine gluconate on the survival of acid fast bacteria.
Mycobacterium and Nocardia species were examined for survival after exposure to chlorhexidine gluconate. In clinical samples M. smegmatis, M. phlei, M. marinum, M. gordonae, M. scrofulaceum, M. kansasii, M. chelonei complex, M. fortuitum, M. flavescens, M. avium, M. xenopi and Nocardia sp. survived pre-treatment with the agent. After exposure of saline suspensions of bacteria to chlorhexidine gluconate, M. smegmatis, M. phlei, M. marinum, M. gordonae, M. pellegrino, N. corallina, N. rubra and Rodochrous gordonae were not recovered, and M. fortuitum and N. asteroides grew poorly.
D002710:Chlorhexidine / Q000494:pharmacology*; D009161:Mycobacterium / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity; D009615:Nocardia / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity; D013045:Species Specificity
D002710:Chlorhexidine