title: [Histological and ultrastructural studies on liver of rats treated with tiadenol].
abstract: By hystological and electronmicroscopical study liver of rats treated with tiadenol at a daily dose of 100 and 200 mg for 30 days, we could demonstrate: lack of necrosis and interstitial phlogosis and, especially in those animals treated with greater doses, numerical increase of peroxisomes, hypertrophy of SER and RER and a lesser regularity of glycogen distribution.
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005233:Fatty Alcohols / Q000494:pharmacology*; D005260:Female; D006651:Histocytochemistry; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D008830:Microbodies / Q000648:ultrastructure; D008854:Microscopy, Electron; D051381:Rats
chemical_list: D005233:Fatty Alcohols; D008112:Liver Glycogen; C004568:tiadenol
vernacular_title: Ricerche istologiche ed ultrastrutturali sul fegato di ratti trattati con tiadenolo.