Observation of quantal release of noradrenaline from vascular smooth muscles in potassium-free solution.
In the electrophysiological studies of the smooth muscle cell of the mesenteric artery, we observed a massive release of noradrenaline from nerve terminals in K-free solution. The nature of K-free induced contraction is discussed in relation to the generation of miniature excitatory junction potentials and drug actions.
D000818:Animals; D004558:Electric Stimulation; D005260:Female; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008564:Membrane Potentials; D008638:Mesenteric Arteries / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000378:metabolism* / Q000502:physiology; D009469:Neuromuscular Junction / Q000502:physiology; D009638:Norepinephrine / Q000378:metabolism*; D010646:Phentolamine / Q000494:pharmacology; D011188:Potassium / Q000502:physiology; D013779:Tetrodotoxin / Q000494:pharmacology
D013779:Tetrodotoxin; D011188:Potassium; D009638:Norepinephrine; D010646:Phentolamine