The eosinophilic fasciitis syndrome after phenytoin (dilantin) therapy.
A young woman with idiopathic temporal lobe epilepsy developed biopsy-proven oesinophilic fasciitis 16 months after the initiation of phenytoin therapy. Six months after withdrawal of this medication the fasciitis disappeared, and after 5 yr it has not recurred. This case highlights a possible association between the development of oesinophilic fasciitis and the use of medications such as phenytoin.
D000328:Adult; D004802:Eosinophilia / Q000139:chemically induced / Q000150:complications*; D004827:Epilepsy / Q000188:drug therapy; D005205:Fascia / Q000473:pathology; D005208:Fasciitis / Q000139:chemically induced / Q000150:complications*; D005260:Female; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D013577:Syndrome
D010672:Phenytoin