Simultaneous assay of bromosulfophthalein and phenolsulfonphthalein in the blood as a test of hepatic and renal functional capacity.
A spectrophotometric procedure for the assay of bromosulfophthalein and phenolsulfonphthalein in the plasma of various animal species and the half-life of the two dyes in plasma representing respectively the rate of liver depuration and that of kidney depuration are described. The method is easy to execute and lends itself particularly well for the simultaneous assessment of hepatic and renal function in the same animal.
D000818:Animals; D004285:Dogs; D005260:Female; D007677:Kidney Function Tests / Q000379:methods*; D007700:Kinetics; D008111:Liver Function Tests / Q000379:methods*; D008297:Male; D010635:Phenolphthaleins / Q000097:blood*; D010637:Phenolsulfonphthalein / Q000097:blood*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013053:Spectrophotometry / Q000379:methods; D013448:Sulfobromophthalein / Q000097:blood*
D010635:Phenolphthaleins; D013448:Sulfobromophthalein; D010637:Phenolsulfonphthalein