title: [Toxicological characteristics of glycol monoacetate].
abstract: Experimental investigations were undertaken to establish the acute and subacute inhalatory, oral and dermal toxicity of glycolmonophosphate. Modern toxicologic, biochemical and pathomorphologic methods were used. It was found that glucomonoacetate has a mild acute and subacute inhalatory, oral and dermal toxicity. The changes in some enzyme activities (GOT, GPT, AP, HE) and the parenchymatous dystrophy of the liver are considered transient and of functional nature. The toxic effect of glucomonoacetate is studied for the first time. Its use in the production of cigarette filters has a definite economical effect.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004781:Environmental Exposure; D005026:Ethylene Glycols / Q000633:toxicity*; D006018:Glycols / Q000506:poisoning; D007928:Lethal Dose 50; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D051381:Rats; D012869:Skin Absorption / Q000187:drug effects; D013997:Time Factors
chemical_list: D005026:Ethylene Glycols; D006018:Glycols; C028001:glycol monoacetate
vernacular_title: Toksikologichna kharakteristika na glikolmonoatsetata.