title: Apparent lack of effect on alpha-bungarotoxin on the spike-induced release of acetylcholine at the mammalian motor end-plate.
abstract: During intoxication with alpha-bungarotoxin (alpha-BGT) the amplitude of end-plate potentials (EPPs) decreased more slowly than the amplitude of potentials evoked by iontophoretically applied acetylcholine. Mean quantal content of EPPs, however, remained constant. The results do not support the notion that alpha-BGT influences, the spike-evoked transmitter release.
mesh_terms: D000109:Acetylcholine / Q000378:metabolism* / Q000494:pharmacology; D000818:Animals; D002038:Bungarotoxins / Q000494:pharmacology*; D003964:Diaphragm / Q000294:innervation; D005071:Evoked Potentials / Q000187:drug effects; D009045:Motor Endplate / Q000187:drug effects*; D009469:Neuromuscular Junction / Q000187:drug effects*; D010791:Phrenic Nerve / Q000187:drug effects; D051381:Rats
chemical_list: D002038:Bungarotoxins; D000109:Acetylcholine