[Achondroplasia is also a neurologic disease].
The achondroplasics' ossification defect produce some changes of the spinal column of such a degree to cause a medullary compression. The AA. refer two cases of neurological complication hospitalized since 1960 in the Clinica delle Mlattie Nervose e Mentali - University of Padua. The clinical evolution of the two patients is considered and compared with the cases known in the Literature; the pathogenetic mechanisms of this disease and the therapeutical perspective are discussed too.
D000130:Achondroplasia / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology; D010292:Paresthesia / Q000209:etiology; D012021:Reflex, Abnormal / Q000209:etiology; D013117:Spinal Cord Compression / Q000209:etiology* / Q000601:surgery; D013131:Spine / Q000473:pathology*
L'acondroplasico è anche un malato neurologico.