"Wedge in -- absorption" phenomenon between erythroblast cells of the bone marrow at dyserythropoiesis.
Bone marrow of healthy persons and patients with dyserythropoiesis caused by chronic diseases and pernicious processes in the stomach were studied under electron microscope. "Septate-like junctions" containing linearly arranged ferritin granules between erythroblasts were found in some patients with gastric cancer. It was shown that the "wedging in" protrusions deepened into the adjacent cell cytoplasm, were detached and absorbed by the erythroblasts. The "wedge in-absorbtion" phenomenon is suggested to be the peculiar mechanism by which ferritin granules are transported into erythroblasts at some dyserythropoietic conditions.
D000747:Anemia, Hypochromic / Q000097:blood*; D000748:Anemia, Macrocytic / Q000097:blood*; D001853:Bone Marrow / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000032:analysis; D004900:Erythroblasts / Q000648:ultrastructure*; D004912:Erythrocytes / Q000648:ultrastructure*; D004920:Erythropoiesis; D005293:Ferritins / Q000032:analysis; D006801:Humans; D007365:Intercellular Junctions / Q000648:ultrastructure*; D013274:Stomach Neoplasms / Q000097:blood
D005293:Ferritins