title: [Electromyographic and histopathological study of the Lambert-Eaton myasthenia syndrome. Apropos of a case].
abstract: In this case of Eaton-Lambert myasthenic syndrome the electrophysiological study demonstrated some modifications of latency of the muscle action potentials evoked by repetitive nerve stimulation at 30 c/sec. specially after administration of edrophonium chloride. This data suggest as possible some fluctuations in the mechanism of the neuromuscular transmission defect. The muscle biopsy showed changes secondary to a peripheral motor nerve involvement; electronmicroscopic study of the motor end-plates revealed a highly developped subneural apparatus.
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D004491:Edrophonium / Q000494:pharmacology; D004558:Electric Stimulation; D004576:Electromyography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009045:Motor Endplate / Q000473:pathology; D009135:Muscular Diseases / Q000473:pathology / Q000503:physiopathology*; D013577:Syndrome
chemical_list: D004491:Edrophonium
vernacular_title: Etude électromyographique et histopathologique du syndrome myasthénique de Lambert-Eaton. A propos d'une observation.