[Aminoethyl derivatives of various 5-aryl-1,3,4-oxadiazol-2-ones: synthesis and pharmacological activity].
In continuation of previous work, the Authors describe the synthesis of 3-aminoethyl derivatives of some 5-aryl-1,3,4-oxadiazol-2-ones whose structure has been confirmed by I.R., N.M.R. and mass spectral methods. The results of pharmacological testing are also reported and these further clarify some aspects of the biological activity of the oxadiazole structure.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D000893:Anti-Inflammatory Agents; D010069:Oxadiazoles
Derivati amminoetilici di alcuni 5-aril-1,3,4-ossadiazol-2-oni: sintesi e attività farmacologica.