[Anatomical and functional characteristics of nerve degeneration and regeneration in traction injuries].
Morphological and functional changes in the nerve after its single extension by 30% of the initial length have been studied in 50 rabbits and dogs by means of neurophysiological and neurohistological techniques for 10 days--6 months. It has been stated that traction lesions result in early trophic disorders, in stable changes of the nerve conductivity and excitation demonstrated in electromyograms from the innervated muscles. The greatest changes (fascicular and axonal breaks) are observed in the zone of trauma. Considerable retrograde changes are observed in the nerve and in corresponding segments of the spinal cord, as well as delayed resorption of the disintegration products of the axial cylinders and myelin membranes both in proximal and peripheral parts of the nerve. After traction lesions, neural fibres restore unevenly, "mosaic" regeneration is observed. Functional and structural-morphological changes in the nerve trunk distinctly correlate with each other, therefore it is possible to prognosticate the degree of the lesions in question.
D000818:Animals; D004285:Dogs; D004576:Electromyography; D005593:Fracture Fixation, Internal; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D010027:Osteotomy; D011817:Rabbits; D012584:Sciatic Nerve / Q000293:injuries / Q000503:physiopathology*; D013997:Time Factors; D014143:Traction / Q000009:adverse effects*
Anatomo-funktsional'nye osobennosti degeneratsii i regeneratsii nervov pri ikh traktsionnykh povrezhdeniiakh.