Verruciform xanthoma of the skin.
Verruciform xanthoma is an unusual lesion characterized by verrucous epithelial proliferation accompanied by a prominent replacement of the dermal papillae with large numbers of foamy histiocytes. Cases have been previously reported only as occurring in the oral cavity or, more rarely, on the vulva. A 16-year-old girl developed a verruciform xanthoma of the skin. The lesion appeared to arise within a large epithelia nevus involving the left inner thigh and inguinal area. This association supports the concept that verruciform xanthoma is a rare inflammatory reaction pattern that may be seen in a variety of squamous epithelial lesions characterized by verrucous hyperplasia.
D000293:Adolescent; D005260:Female; D006801:Humans; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*; D014860:Warts / Q000473:pathology*; D014973:Xanthomatosis / Q000473:pathology*