Measurement of total body water in patients on maintenance hemodialysis using an ethanol dilution technique.
The applicability of the ethanol dilution (ED) technique for total body water (TBW) determination in uremic patients was studied. 73 TBW measurements were performed on 28 patients. As the basic parameters underlying the ED technique showed nearly normal values (Widmark factor r = 0.722 plus or minus 0.0786, normal = 0.710 plus or minus 0.090 g/kg; beta 60 = 0.121 plus or minus 0.037, normal = 0.140 plus or minus 0.018 g/kg x 60 min; "rectilinear' course of the blood ethanol elimination curve), the ED technique for TBW measurements is well applicable to uremic patients. Subclinical hyperhydration was diagnosed (TBW = 57.88 plus or minus 8.08% of body weight, normal = 52.6 plus or minus 5.4%) in 61% of the cases.
D000328:Adult; D000368:Aged; D001834:Body Water / Q000032:analysis*; D000431:Ethanol / Q000097:blood; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D008297:Male; D008722:Methods; D008875:Middle Aged; D006435:Renal Dialysis
D000431:Ethanol