[New aspects in the clinical picture of malignant hyperthermia (author's transl)].
The key factor in malignant hyperthermia does not seem to be a defect in the calcium-storing membrane of the skeletal and cardiac muscle cells. The primary cause would appear to be deficiency of adenylate kinase.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000263:Adenylate Kinase / Q000378:metabolism; D000328:Adult; D002118:Calcium / Q000378:metabolism; D002648:Child; D003402:Creatine Kinase / Q000378:metabolism; D003620:Dantrolene / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008274:Magnesium / Q000378:metabolism; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000201:enzymology; D009132:Muscles / Q000201:enzymology
D000255:Adenosine Triphosphate; D003402:Creatine Kinase; D000263:Adenylate Kinase; D003620:Dantrolene; D008274:Magnesium; D002118:Calcium
Neue Aspekte zum Krankheitsbild der malignen Hyperthermie und seine Therapie.