Spontaneous lysosomal enzyme secretion by a murine macrophage-like cell line.
Lysosomal enzyme secretion by the murine macrophage-like cell line, P388D1, was compared with that of normal peritoneal macrophages. Unlike macrophages, lysosomal hydrolase secretion by P388D1 cells occurred spontaneously in vitro and was not further stimulated by the presentation of inflammatory agents such as zymosan and asbestos.
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D002460:Cell Line; D006596:Hexosaminidases / Q000378:metabolism; D006867:Hydrolases / Q000378:metabolism*; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology*; D008264:Macrophages / Q000187:drug effects / Q000201:enzymology*; D051379:Mice
D006867:Hydrolases; D006596:Hexosaminidases