title: Biochemical genetics of glutathione-S-transferase in man.
abstract: Glutathione-S-transferases from liver and erythrocytes have been separated by starch gel electrophoresis and localized by a specific staining procedure. The data suggest that the most active glutathione-S-transferases in liver are the products of two autosomal loci, GST1 and GST2. Both these loci are polymorphic, and there is evidence that a common null allele exists at the GST1 locus. The glutathione-S-transferase expressed in erythrocytes is the product of a third locus, GST3, and is not polymorphic.
mesh_terms: D002874:Chromosome Mapping; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000201:enzymology; D005796:Genes; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008099:Liver / Q000201:enzymology; D011110:Polymorphism, Genetic
chemical_list: D005982:Glutathione Transferase