[One case of acquired dyserythropoietic anemia: morphologic cytochemical study (author's transl)].
A case of acquired dyserythropoietic anemia is described in a sixty-six year old patient: is characterized by a very considerable pancitopenia, and by the presence in the bone-marrow of notable morphologic atipia both in erythroblastic line and in granulocitopoietic one. The iron kinetics and erythrocitic surviving are highly altered. The citochimic study points out the presence of myelocites with perossidasis-deficit and the presence of PAS positive erythroblasts. These data indicate metabolic anomalies that seem to localize the primitive deficit in the stem-cells.
D000743:Anemia, Hemolytic / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D001854:Bone Marrow Cells; D004900:Erythroblasts / Q000166:cytology; D004905:Erythrocyte Aging; D006098:Granulocytes / Q000166:cytology; D006651:Histocytochemistry; D006801:Humans; D007501:Iron / Q000378:metabolism; D008875:Middle Aged; D010198:Pancytopenia / Q000150:complications
D007501:Iron
Un caso di anemia diseritropoietica acquisita. Studio morfologico e citochimico.