title: A stepped forty-eighty hour manic-depressive cycle.
abstract: This paper describes a patient with an almost 48-hour manic-depressive cycle but with a daily shift of the switching time, the latter having itself a cycle of five days. The mood change always occurred gradually and during the day, never at night. Between manic and depressive phases there was a difference in the frequency of the EEG alpha rhythm. The patient showed a good response to lithium treatment.
mesh_terms: D000368:Aged; D000513:Alpha Rhythm; D001714:Bipolar Disorder / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D010507:Periodicity
chemical_list: D008094:Lithium