Chemotherapy of Babesia microti infections in Mongolian Jirds.
For identifying drugs which might be effective in the treatment of human Babesia microti infections, 20 selected antiprotozoal agents or combinations of agents were tested for activity against B. microti in Mongolian jirds (meriones unguiculatus). 4-Methyl-primaquine and aromatic diamidines, including diminazene and pentamidine, were the most effective compounds tested.
D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D001404:Babesiosis / Q000188:drug therapy*; D005849:Gerbillinae; D008297:Male; D013329:Structure-Activity Relationship
D000981:Antiprotozoal Agents