title: [Importance of aspiration puncture of the thyroid gland and of the determination of autoantibodies to its tissue in the diagnosis of autoimmune lesions of the organ in an endemic goiter locality].
abstract: Comparative studies on the effectiveness of aspiration puncture of the thyroid gland and detection of autoantibodies to its tissue were carried out in 523 patients operated for nodose non-toxic goitre and living in the different goitre-endemic areas. The puncture results and autoantibody detection (before surgery) were compared with the histological findings. It is concluded that the aspiration puncture more adequately than autoantibody detection reflects the histological type of autoagression in endemic goitre combined with phenomena of autoimmunity to the thyroid gland tissue. Nevertheless, autoantibody detection in these patients more frequently provides positive results. Therefore it is recommended that both methods be used simultaneously.
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D001707:Biopsy, Needle; D004197:Disease Reservoirs; D005260:Female; D006043:Goiter, Endemic / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012800:Siberia; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology*
chemical_list: D001323:Autoantibodies
vernacular_title: Znachenie aspiratsionnoĭ punktsii shchitovidoĭ zhelezy i opredeleniia autoantitel k ee tkani v diagnostike autoimmunnykh porazheniĭ organa v usloviiakh éndemichnoĭ po zobu mestnosti.