[Hydrophobic peptide possessing growth activity from the trypsin hydrolysate of sperm whale somatotropin].
Hydrophobic 31-member peptide exerting a considerable growth effect in "tibia-test" was extracted in a homogenous state from trypsin hydrolyzate of cachalot somatotropin. Comparison of N-end (1--11) aminoacid succession of peptide content with known somatotropin structure allows a conclusion that the peptide represents the 77th to 107th ingredient of the hormone polipeptide chain. The peptide studied has no analogues among somatotropin ingredients described in the literature capable of retaining the growth effect and having the shortest structure.
D000595:Amino Acid Sequence; D000818:Animals; D002591:Cetacea; D006128:Growth / Q000187:drug effects*; D013006:Growth Hormone / Q000032:analysis*; D006868:Hydrolysis; D007016:Hypophysectomy; D010454:Peptide Termination Factors / Q000032:analysis; D010455:Peptides / Q000032:analysis / Q000302:isolation & purification*; D010902:Pituitary Gland / Q000032:analysis; D051381:Rats; D013977:Tibia / Q000187:drug effects; D014357:Trypsin / Q000494:pharmacology*; D014907:Whales
D010454:Peptide Termination Factors; D010455:Peptides; D013006:Growth Hormone; D014357:Trypsin
Gidrofobnyĭ peptid iz tripsinovogo gidrolizata somatotropina kashalota, obladaiushchiĭ rostovoĭ aktivnost'iu.