title: Hereditary deafness in the cat: an electron-microscopic study of the tectorial membrane.
abstract: The tectorial membrane is affected at an early stage of the cochlear degeneration in the hereditarily deaf white cat. The membrane first descends towards the organ of Corti with obliteration of the intervening sub-tectorial space in the basal coil during the second post-natal week. Both the microvilli of supporting and Hensen's cells, and the hair cell stereocilia make deep indentations on the under-surface of the membrane. Cells are found insinuated between the tectorial membrane and Corti's organ, and numerous cellular processes occur within the former. A phagocytic function would appear probable for these cells, which seem to originate from the internal sulcus region. The membrane is retracted into the latter around the 2-month stage. At all ages, small spherical structures, which may represent altered interdental cell secretions, are found within the membrane, these becoming calcified in older animals.
mesh_terms: D000818:Animals; D001284:Atrophy; D002415:Cats; D003051:Cochlea / Q000648:ultrastructure*; D003638:Deafness / Q000235:genetics* / Q000473:pathology / Q000662:veterinary; D008854:Microscopy, Electron; D013680:Tectorial Membrane / Q000648:ultrastructure*