[The effect of Urografin on sensorineural deafness. A clinical study (author's transl)].
Prof. Morimitsu (Fukuoka, Japan) reported a case of hearing improvement after the intravenous administration of Urografin in 1976. Because we had a similar case, injected 10 ml of Urografin (76%) intravenously in 130 patients with sensorineural deafness and tinnitus, which had not improved with previous treatment consisting of vasodilators and stellate ganglion blocks. 21 patients had a hearing improvement after Urografin-therapy; the tinnitus disappeared in 8 cases, and 2 patients noticed an improvement of their hearing and tinnitus. No adverse reactions to these injections, except for one case with a mild cutaneous allergy, were observed. The data did not reveal any particular clinical or audiological criteria which indicated a favourable prognosis with Urografin-therapy.
D003638:Deafness / Q000188:drug therapy*; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D014012:Tinnitus / Q000188:drug therapy
D003973:Diatrizoate; D003974:Diatrizoate Meglumine
Erfahrungen mit der Gabe von Urografin bei Innenohrschwerhörigkeit.