title: The computer leucocyte. Analysis of the random movement of leucocytes in a visual field by means of computer simulation.
abstract: In vital preparations moving polymorphonuclear leucocytes (PMNs) disappear from the visual field. The present study provides evidence by means of geometrical analysis and computer simulation, that this disappearance is due to a heterogeneous distribution of the PMNs at the beginning of observation. The path of random-moving computer leucocytes is more tortuous than the path of comparable vital PMNs without obvious attractant, i.e. vital PMNs supposed to be random-moving. This finding is in agreement with the Allan-Wilkinson observation of 'persistent random walk' of vital cells.
mesh_terms: D002465:Cell Movement; D003201:Computers; D006801:Humans; D009504:Neutrophils / Q000502:physiology*; D011336:Probability