title: [Effect of concanavalin A on the splenic lymphocyte proliferative activity of germ-free rats].
abstract: Action of Con-A on the proliferative activity of spleen lymphocytes was studied using germfree and conventional Fisher rats 3-4 months of age and conventional 2-3 day old rats. The intensity of 3H-thymidine incorporation in lymphocytes of germfree and conventional animals was the same, however, the coefficient of stimulation was higher in germfree rats. Lymphocytes of suckling rats had a low reactivity to Con-A.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002455:Cell Division / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology*; D005260:Female; D005856:Germ-Free Life / Q000187:drug effects*; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D051381:Rats; D013154:Spleen / Q000166:cytology*
chemical_list: D003208:Concanavalin A
vernacular_title: Vliianie konkanavalina A na proliferativnuiu aktivnost' limfotsitov selezenki bezmikrobnykh krys.