Increases in skin resistance of white rats following scopolamine injection.
Thirty-six male albino rats were injected with either saline or 0.6 mg/kg scopolamine and placed on a metal grid. The grid was wired to a transistor-biased detector which determined, every second, whether the subject's resistance was above or below a preset threshold value. Over test sessions of five minutes, drug subject's resistances were above each of the three threshold values used (5, 10, 15 megohms) for significantly longer than those of control subjects. Scopolamine treated rats would therefore receive lower shock levels than control subjects in a shock experiment.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D005712:Galvanic Skin Response / Q000187:drug effects*; D008297:Male; D051381:Rats; D012601:Scopolamine / Q000494:pharmacology*
D012601:Scopolamine