title: Pattern of peptide synthesis in Drosophila cell lines and their hybrids.
abstract: Significant changes occurred in the rate of synthesis of several polypeptides in two different Drosophila cell lines following exposure to the steroid hormone, beta-ecdysone. For peptide 7/8, the synthetic rate increased by a factor of 10 in line S3 and by a factor of 1.3 in line MDR. In hormone-sensitive hybrids the rate increased by a factor of 3-4.5. For peptide 10 the synthetic rate decreased by a factor of 8 in line S3 but increased by a factor of 2 in line MDR. In hormone-sensitive hybrids the synthetic rate increased by a factor of 2-3. In hormone-insensitive cell lines no change in the rate of peptide synthesis occurred in the presence of hormone.
mesh_terms: D000818:Animals; D001345:Autoradiography; D002460:Cell Line; D004330:Drosophila / Q000235:genetics / Q000378:metabolism*; D004440:Ecdysone / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D006822:Hybrid Cells / Q000378:metabolism*; D010641:Phenotype; D014176:Protein Biosynthesis; D013045:Species Specificity
chemical_list: D004440:Ecdysone