title: Culture of isolated glomeruli from normal and nephritic rabbits. II. Kinetics of outgrowing cells.
abstract: In the autologous phase of nephrotoxic nephritis in the rabbit, many round (Type III) cells appeared in the glomerular outgrowth. They had receptors for Fc and C3 and a pronounced phagocytic capacity for carbon. The number of Type III cells in the glomerular outgrowth from rabbits 8 days after injection of nephrotoxic serum (NTS-8) was higher than that of NTS-10 or -15. In contrast, they were rarely observed in the outgrowth of glomeruli from normal and NTS-3 rabbits. The Type II (fusiform) cell, a type of intrinsic glomerular cell, was also increased earlier and more markedly in NTS-8, -10, and -15 than in normal and NTS-3 rabbits.
mesh_terms: D000818:Animals; D002452:Cell Count; D046508:Culture Techniques; D005921:Glomerulonephritis / Q000276:immunology; D007678:Kidney Glomerulus / Q000166:cytology / Q000473:pathology*; D007700:Kinetics; D008264:Macrophages / Q000502:physiology; D008297:Male; D011817:Rabbits; D011951:Receptors, Complement / Q000378:metabolism; D011961:Receptors, Fc / Q000378:metabolism
chemical_list: D011951:Receptors, Complement; D011961:Receptors, Fc