title: A similarity ring for amino acids based on their evolutionary substitution rates.
abstract: A similarity ring for amino acids is obtained by reordering the rows and columns of their substitution probability matrix so as to minimize the variance of the matrix elements about the main diagonal.
mesh_terms: D000595:Amino Acid Sequence; D005075:Biological Evolution; D003201:Computers; D008956:Models, Chemical; D011336:Probability