Sulindac-induced anaphylaxis.
This communication describes the first known report of sulindac-induced anaphylaxis. A 17-year-old patient who ingested a single tablet of sulindac developed pruritus, hives, and dyspnea. Blood pressure was not detectable. The patient was treated with epinephrine, a corticosteroid, and an antihistamine. Recovery was complete. The ability of this class of drugs to produce dangerous reactions is discussed.
D000328:Adult; D000707:Anaphylaxis / Q000209:etiology*; D001171:Arthritis, Juvenile / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D007192:Indenes / Q000009:adverse effects*; D013467:Sulindac / Q000009:adverse effects*
D007192:Indenes; D013467:Sulindac