title: The effect of histamine and epinephrine on adenylate cyclase prepared from dog ventricle.
abstract: The possible presence of histamine H2 receptors in dog ventricle was investigated by determining the effect of histamine on adenylate cyclase prepared from that tissue. Epinephrine produced a dose-dependent increase in adenylate cyclase activity but histamine had no effect. Histamine H2 receptors probably do not exist in dog ventricle.
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D004285:Dogs; D004837:Epinephrine / Q000494:pharmacology*; D006160:Guanosine Triphosphate / Q000502:physiology; D006632:Histamine / Q000494:pharmacology*; D066298:In Vitro Techniques; D009206:Myocardium / Q000201:enzymology*
chemical_list: D006632:Histamine; D006160:Guanosine Triphosphate; D000262:Adenylyl Cyclases; D004837:Epinephrine