title: 47,XXY males: sex chromosomes and tooth size.
abstract: Permanent tooth crowns of 47,XXY males were found to be generally larger than those of control males and females and their first-degree male and female relatives. These results suggest that tooth-size increase in 47,XXY males is due to a direct genetic effect and support the concept of the presence of a specific growth gene (or genes) in the human X and Y chromosomes. The effect of this gene (or genes) seems to be the promotion of tooth growth, and the Y chromosome is more effective than the X chromosome in this respect.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009811:Odontometry; D012729:Sex Chromosome Aberrations / Q000235:genetics; D012730:Sex Chromosomes; D014070:Tooth / Q000033:anatomy & histology* / Q000254:growth & development; D014997:XYY Karyotype / Q000235:genetics