Eccrine sweat gland carcinoma of the eyelid with orbital involvement.
A 70-year-old man had a sweat gland carcinoma in his right upper eyelid that was slowly growing, but it clinically remained confined to the lid tissues for a period of 25 years. The tumor ultimately extended deeper into the orbit and invaded the sclera, the optic nerve sheath, and the ethmoidal sinuses. Histopathologic examination disclosed malignant features with a variety of cellular patterns. The results of electron microscopic studies confirmed the origin of the tumor from the eccrine sweat glands.
D000368:Aged; D001706:Biopsy; D005142:Eyelid Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed