Chronic thinner intoxication: clinico-pathologic report of a human case.
A 27 year old Mexican male addicted for 12 years to glue-sniffing and thinner inhalation developed neurological and behavioural disturbances which led to hospital admission and death. Autopsy disclosed diffuse cerebral and cerebellar cortex atrophy and giant axonopathy both central and peripheral. The corpus callosum was atrophic secondarily to neuron loss in the neocortex.
D000328:Adult; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000473:pathology; D002525:Cerebellar Cortex / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects; D006801:Humans; D008297:Male; D008800:Mexico; D009410:Nerve Degeneration / Q000187:drug effects; D009413:Nerve Fibers, Myelinated / Q000187:drug effects; D012997:Solvents / Q000506:poisoning*; D013116:Spinal Cord / Q000187:drug effects; D019966:Substance-Related Disorders / Q000473:pathology*
D012997:Solvents