[A Swiss family with the red cell antigen Pk (author's transl)].
The first Swiss family with the very rare bloodgroup Pk is described. It was possible to construct the family tree through 7 generations. Due to intermarriage between cousins, the 5 Pk people can be traced back to one of three ancestors. Coupling of the gene f[3], which leads to the production of the antigene Pk on erythrocytes when in homozygote condition, with an other blood group system, could not be recorded. Natural anti-P was found in all of the Pk peoples' serum. The haemolysing effect in an incompatible transfusion, probably due to anti-P, is shown in one example.
D001789:Blood Group Antigens; D005260:Female; D006461:Hemolysis; D006801:Humans; D007518:Isoantibodies / Q000032:analysis; D008297:Male; D010127:P Blood-Group System; D010375:Pedigree; D013557:Switzerland; D065227:Transfusion Reaction
D001789:Blood Group Antigens; D007518:Isoantibodies; D010127:P Blood-Group System
Eline Schweizer Familie mit dem Erythrozytenantigen Pk.