Chromosomal analysis as prognostic tool in transitional cell carcinoma: preliminary report.
Twelve patients with transitional cell carcinomas were studied for chromosomal abnormalities correlated with cystoscopic and histologic findings. The tumors with abnormal chromosome "markers" or numbers (aneuploidy or polyploidy) appeared to be more aggressive or recurred more frequently than those with normal chromosome patterns.
D000368:Aged; D000782:Aneuploidy; D002295:Carcinoma, Transitional Cell / Q000235:genetics*; D002869:Chromosome Aberrations; D002900:Chromosomes, Human, 1-3; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics*; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D011123:Polyploidy; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000235:genetics*; D014998:Y Chromosome