[Pulmonary oedema as a complication of tocolytic therapy (author's transl)].
Tocolytic treatment with fenoterol and additional administration of betamethasone and acetyl salicylic acid to a 19-year-old girl caused irreversible and finally fatal pulmonary changes. The clinical course in this and that of other published cases indicates a causal relationship between the tocolytic treatment and the onset of pulmonary oedema. The pulmonary arterial pressures in this patient, the poor therapeutic response and the shock-lung picture without corresponding myocardial changes suggest a non-cardiogenic cause of pulmonary oedema. Any of the three drugs administered could have been responsible.
D000328:Adult; D001241:Aspirin / Q000009:adverse effects; D001344:Autopsy; D001623:Betamethasone / Q000009:adverse effects; D004983:Ethanolamines / Q000009:adverse effects*; D005260:Female; D005280:Fenoterol / Q000009:adverse effects*; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D011247:Pregnancy; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000473:pathology; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000473:pathology
D004983:Ethanolamines; D005280:Fenoterol; D001623:Betamethasone; D001241:Aspirin
Lungenödem als Tokolyse-Komplikation.