[Quality and stability of tetracycline tablets].
Tetracycline base tablets with dragee (sugar) and gastric soluble film coatings were investigated. Advantages of the tablets with the film coating in the main characteristics, such as bioavailability and levels of tetracycline-like admixtures were shown. The structure of the surface layer of the dragee coating was studied. It was found that the products contained in the coating and magnesium carbonate, in particular, lowered the tablet solubility.
D004355:Drug Stability; D007700:Kinetics; D010592:Pharmaceutic Aids / Q000494:pharmacology; D011786:Quality Control; D013607:Tablets; D013752:Tetracycline / Q000494:pharmacology*; D014961:X-Ray Diffraction
D010592:Pharmaceutic Aids; D013607:Tablets; D013752:Tetracycline
Kachestvo i stabil'nost' tabletok tetratsiklina.