title: Protein splicing: self-splicing of genetically mobile elements at the protein level.
abstract: Protein splicing is a newly discovered process that is the protein equivalent of RNA splicing. Protein splicing proceeds through a branched protein intermediate, and in vitro studies indicate that the reaction is autocatalytic. The excised 'intein' proteins are site-specific DNA endonucleases that catalyse genetic mobility of their DNA coding sequence by an 'intein homing' mechanism.
mesh_terms: D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D012326:RNA Splicing
chemical_list: D011506:Proteins