title: Somatic mutation of human immunoglobulin V genes: bias, rate, and regulation.
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000235:genetics / Q000276:immunology; D016667:Bacterial Capsules; D023201:CD40 Ligand; D017637:Clonal Deletion; D003062:Codon; D015322:Gene Rearrangement, B-Lymphocyte; D005803:Genes, Immunoglobulin; D018073:Haemophilus Vaccines / Q000276:immunology; D006193:Haemophilus influenzae / Q000276:immunology; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007132:Immunoglobulin Isotypes / Q000235:genetics; D007075:Immunoglobulin M / Q000235:genetics / Q000276:immunology; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D007153:Immunologic Deficiency Syndromes / Q000235:genetics / Q000276:immunology; D008562:Membrane Glycoproteins / Q000502:physiology; D051379:Mice; D018345:Mice, Knockout; D005810:Multigene Family; D009154:Mutation; D011135:Polysaccharides, Bacterial / Q000276:immunology; D018074:Vaccines, Conjugate / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D003062:Codon; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D007143:Immunoglobulin Heavy Chains; D007132:Immunoglobulin Isotypes; D007075:Immunoglobulin M; D007135:Immunoglobulin Variable Region; D008562:Membrane Glycoproteins; D011135:Polysaccharides, Bacterial; D018074:Vaccines, Conjugate; D023201:CD40 Ligand