title: N-[(1-butyl-4-piperidinyl)methyl]-3,4dihydro-2H-[1,3]oxazino[3,2- a]indole10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004146:Dioxanes / Q000494:pharmacology; D004285:Dogs; D006168:Guinea Pigs; D007211:Indoles / Q000138:chemical synthesis / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D010880:Piperidines / Q000138:chemical synthesis / Q000494:pharmacology*; D011985:Receptors, Serotonin / Q000187:drug effects*; D044422:Receptors, Serotonin, 5-HT4; D012702:Serotonin Antagonists / Q000138:chemical synthesis / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000494:pharmacology
chemical_list: D004146:Dioxanes; D007211:Indoles; D010880:Piperidines; D011985:Receptors, Serotonin; C096919:SB 207266; D012702:Serotonin Antagonists; D013449:Sulfonamides; C084858:SB 204070A; D044422:Receptors, Serotonin, 5-HT4; C082871:GR 113808