The use of intravenous nitroglycerin for emergency cervico-uterine relaxation.
A patient with a twin pregnancy was in preterm labour after 25 gestational weeks when, during vaginal delivery of the second twin, severe spasm of the cervix and fetal bradycardia ensued. Induction of general anesthesia did not relax the cervix. After bolus doses of nitroglycerin 100 + 50 micrograms i.v., prompt cervico-uterine relaxation was obtained allowing manual extraction of the baby. A short review of the literature and a summary of our experience in the administration of nitroglycerin i.v. in obstetrics are presented.
D000328:Adult; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D002584:Cervix Uteri / Q000187:drug effects; D004630:Emergencies; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D009126:Muscle Relaxation / Q000187:drug effects*; D005996:Nitroglycerin / Q000008:administration & dosage*; D007744:Obstetric Labor Complications / Q000188:drug therapy*; D007752:Obstetric Labor, Premature / Q000503:physiopathology; D011247:Pregnancy; D011272:Pregnancy, Multiple; D013035:Spasm / Q000188:drug therapy*; D014427:Twins; D002577:Uterine Cervical Diseases / Q000188:drug therapy*; D014590:Uterine Contraction / Q000187:drug effects
D005996:Nitroglycerin