title: Stimulation of glossopharyngeal and laryngeal nerve afferents induces expulsion only when it is applied during retching in paralyzed decerebrate dogs.
abstract: Stimulation of the oropharyngeal mucosa induces vomiting in humans, however, it has not been seen in animals. Thus, we attempted to induce fictive vomiting by stimulation of lingual and pharyngeal branch afferents of the glossopharyngeal nerve, and afferents of the superior and recurrent laryngeal nerves in paralyzed decerebrate dogs. The stimulation did not induce fictive vomiting when it was applied during eupnea, but induced fictive expulsion when it was applied during fictive retching. Threshold intensity for the induction decreased with the progress of retching.
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D003655:Decerebrate State / Q000503:physiopathology*; D004285:Dogs; D004558:Electric Stimulation; D005930:Glossopharyngeal Nerve / Q000502:physiology*; D007823:Laryngeal Nerves / Q000502:physiology*; D010243:Paralysis / Q000503:physiopathology*; D012684:Sensory Thresholds; D014839:Vomiting / Q000503:physiopathology*