Dual recognition of lipid A and DNA by human antibodies encoded by the VH4-21 gene. A possible link between infection and lupus.
D000595:Amino Acid Sequence; D000744:Anemia, Hemolytic, Autoimmune / Q000235:genetics / Q000276:immunology; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D000974:Antibodies, Antinuclear / Q000235:genetics / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D001424:Bacterial Infections / Q000276:immunology*; D003429:Cross Reactions; D004247:DNA / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D005803:Genes, Immunoglobulin; D006388:Hemagglutinins / Q000235:genetics / Q000276:immunology; D006801:Humans; D007048:I Blood-Group System / Q000276:immunology*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007075:Immunoglobulin M / Q000235:genetics / Q000276:immunology; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D008050:Lipid A / Q000276:immunology*; D008180:Lupus Erythematosus, Systemic / Q000209:etiology / Q000235:genetics / Q000276:immunology*; D018716:Molecular Mimicry; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D000888:Antibodies, Anti-Idiotypic; D000974:Antibodies, Antinuclear; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D001324:Autoantigens; D006388:Hemagglutinins; D007048:I Blood-Group System; D007143:Immunoglobulin Heavy Chains; D007075:Immunoglobulin M; D007135:Immunoglobulin Variable Region; D008050:Lipid A; D004247:DNA