[Changes in the intraerythrocytic proteolysis of human hemoglobin in lymphogranulomatosis].
The data obtained on red cell hemolysates from 16 patients with Hodgkin's disease varying in age, sex, the disease stage and histology, time since the diagnosis served the basis for comparative evaluation of endogenic intraerythrocytic hemoglobin proteolysis and relevant products. The results show that Hodgkin's disease brings about a 10-15-fold increase in the quantity of accumulated hemoglobin alpha-chain fragments.
D000293:Adolescent; D000328:Adult; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D004912:Erythrocytes / Q000737:chemistry / Q000201:enzymology*; D005260:Female; D006454:Hemoglobins / Q000032:analysis / Q000378:metabolism*; D006689:Hodgkin Disease / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010447:Peptide Hydrolases / Q000097:blood*
D006454:Hemoglobins; D010447:Peptide Hydrolases
Izmeneniia vnutriéritrotsitarnogo proteoliza gemoglobina cheloveka pri limfogranulematoze.