Respiratory syncytial virus, a rare cause of severe pneumonia following bone marrow transplantation.
Mixed alveolar interstitial pneumonia is a much-feared complication in bone marrow transplant recipients because it carries a high mortality. Many cases in which an etiological agent is identified are due to fungi or cytomegalovirus; rarely, other infectious agents such as Pneumocystis carinii or (para)influenzavirus are involved. In this report we describe a patient who received intense chemotherapy followed by autologous bone marrow transplantation for relapse of testis seminoma and who developed a severe alveolar interstitial pneumonia caused by respiratory syncytial virus in the early posttransplant period. The patient fully recovered after treatment with ribavirin.
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000821:virology; D008297:Male; D011024:Pneumonia, Viral / Q000821:virology*; D011859:Radiography; D018357:Respiratory Syncytial Virus Infections / Q000000981:diagnostic imaging / Q000188:drug therapy; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification; D012254:Ribavirin / Q000627:therapeutic use; D018239:Seminoma / Q000628:therapy; D013736:Testicular Neoplasms
D012254:Ribavirin