title: [Myocardial ischemia and anesthesia].
abstract: Patients with coronary artery disease are particularly at risk perioperatively, as myocardial infarction, unstable angina, severe arrhythmia and cardiac death may occur. These events are often preceded by prolonged silent myocardial ischaemia (MI). Moreover, perioperative MI predicts long-term adverse cardiac outcome. Therefore, it is logical to prevent and treat MI. However, the detection of perioperative MI is difficult because of low sensitivity of ST-segment monitoring, low specificity of echocardiography and insufficient availability of equipment for its monitoring. A pragmatic approach is described, including preoperative consideration of myocardial revascularization prior to non-cardiac surgery and perioperative administration of antianginal agents; the effects of clonidine are discussed as well. The role of anaesthetic techniques and normovolaemic haemodilution is considered. MI episodes may be prevented or their duration may be shortened by treating tachycardia, hypotension and, possibly, hypertension. The risks of MI are particularly high during the postoperative period because increased global oxygen consumption associated with recovery, ventilator weaning, shivering and pain may lead to tachycardia and increased ventricular load. These factors must be taken into account in order to prevent MI and improve postoperative cardiac outcome.
mesh_terms: D000758:Anesthesia; D004452:Echocardiography; D004562:Electrocardiography; D006439:Hemodynamics; D006801:Humans; D008991:Monitoring, Physiologic; D017202:Myocardial Ischemia; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption; D011237:Predictive Value of Tests; D012307:Risk Factors
vernacular_title: Ischémie myocardique et anesthésie.