title: Klebsiella oxytoca meningitis: frequent association with neurosurgical procedures.
abstract: Klebsiella oxytoca meningitis is a rare condition. Nine patients were diagnosed between 1981 and 1993 at our institution. These accounted for 2.3% of 393 patients with blood and/or cerebrospinal fluid culture-proven bacterial meningitis. K. oxytoca was noted in both community-acquired meningitis and nosocomial meningitis. Eight of the nine cases were patients who had undergone neurosurgical procedures. Four were mixed bacterial meningitis. All K. oxytoca isolates were susceptible to third-generation cephalosporins and all but one to chloramphenicol. Antibiotic therapy was successful in eight patients but failed in one.
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000209:etiology / Q000382:microbiology; D001927:Brain Diseases / Q000601:surgery; D002511:Cephalosporins / Q000627:therapeutic use; D002555:Cerebrospinal Fluid / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007709:Klebsiella / Q000302:isolation & purification*; D007710:Klebsiella Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011183:Postoperative Complications
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins