Determination of the cyclic GMP concentration yielding half-maximal activation of cyclic GMP-dependent protein kinase in intact ovine basilar arteries.
D000818:Animals; D001488:Basilar Artery / Q000187:drug effects / Q000201:enzymology; D006152:Cyclic GMP / Q000378:metabolism*; D017869:Cyclic GMP-Dependent Protein Kinases / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000201:enzymology*; D010396:Penicillamine / Q000031:analogs & derivatives / Q000494:pharmacology; D011863:Radioimmunoassay; D026423:S-Nitroso-N-Acetylpenicillamine; D012756:Sheep; D014665:Vasodilator Agents / Q000494:pharmacology
D014665:Vasodilator Agents; D026423:S-Nitroso-N-Acetylpenicillamine; D017869:Cyclic GMP-Dependent Protein Kinases; D010396:Penicillamine; D006152:Cyclic GMP