A preliminary investigation of an association between dental restorations and carcinoma of the tongue.
The potential association of dental restorations and tongue carcinoma was studied. We reviewed the available pretreatment dental records of 133 patients with carcinoma of the tongue seen at the British Columbia Cancer Agency between 1958 and 1992. 75 patients had teeth adjacent to the ipsilateral side of the cancer (involved side) and the contralateral (control) side of the tongue, resulting in 150 tongue/teeth pairings. Overall there was no significant association between the presence of dental fillings and tongue carcinoma, as the prevalence of bilateral dental restorations was high. Dental restorations were found in 6 patients on the involved side only. Only 1 patient developed a cancer adjacent to normal teeth with contralateral restorations. We feel that this observation merits more study. Meanwhile, careful assessment of dentition and aggressive treatment of dysplastic lesions are warranted.
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D003793:Dental Restoration, Permanent / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014062:Tongue Neoplasms / Q000209:etiology* / Q000473:pathology