Retinal vasculitis caused by rubella.
A patient with vasculitis apparently caused by rubella and diagnosed during her life-time is here presented. The girl showed optic neuritis and large vascular changes in the eye fundi (retinal vasculitis). High intrathecal antibody production against rubella but little or none against other viruses was found in the cerebrospinal fluid. This study suggests that immunoactivation after rubella vaccination may remain and lead to vascular changes.
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007223:Infant; D008213:Lymphocyte Activation; D016131:Lymphocyte Subsets; D012171:Retinal Vessels / Q000503:physiopathology*; D012409:Rubella / Q000276:immunology / Q000517:prevention & control / Q000821:virology*; D012411:Rubella Vaccine; D012412:Rubella virus / Q000302:isolation & purification / Q000472:pathogenicity*; D014611:Vaccination; D014657:Vasculitis / Q000209:etiology* / Q000503:physiopathology*
D007074:Immunoglobulin G; D012411:Rubella Vaccine