Safe and normothermic massive transfusions by modification of an infusion warming and pressure device.
A fluid-warming pressure infusion device (H-500/H25i, Level 1) was modified to meet the demands for safe, normothermic, and effective massive transfusions. By incorporating an autoventing 40 microns filter (Pall AV-SP), which was originally manufactured for use in an extracorporal circulation, the risk of accidental air embolism can be eliminated. Feasibility and efficiency of this model were tested in ten patients. The mean volume transfused and infused (packed red cells and colloids) was 6750 mL (SD +/- 2519) during a mean period of acute volume resuscitation of 55 minutes (SD +/- 30). Calculated flow rates averaged 140 mL/min, which were sufficient to stabilize all but one patient. This patient subsequently died because of uncontrollable surgical bleeding. Body temperature remained stable with a minimal mean drop of -0.3 degrees C. Supplying the Level 1 warming and pressure device with a Pall AV-SP filter allows for safe, effective, and demand-adapted massive transfusions in a large number of trauma patients at a reasonable cost.
D001803:Blood Transfusion / Q000295:instrumentation*; D001831:Body Temperature; D004618:Embolism, Air / Q000517:prevention & control; D005240:Feasibility Studies; D005374:Filtration / Q000295:instrumentation; D006361:Heating / Q000295:instrumentation*; D006470:Hemorrhage / Q000628:therapy*; D006801:Humans; D011312:Pressure; D012151:Resuscitation / Q000295:instrumentation