Modification of fat and carbohydrate metabolism by neurohypophyseal hormones. II. Effect of lysine-vasopressin on non-esterified fatty acid, glucose, triglyceride and cholesterol levels in the serum of male rats.
The effect of subcutaneously injected lysine-vasopressin on serum non-esterified fatty acid, triglyceride, cholesterol and glucose levels in fed and fasting male rats given doses of 2.5 and 5 I.U./kg was determined. About 15 min after starting the experiment, non-esterified fatty acid levels abruptly fell and glucose levels rose in both fed and fasting animals. The only exception were fed males given a dose of 5 I.U./kg in which there was a delayed increase in the non-esterified fatty acid level. Triglyceride levels rose in fed males and fell in fasting males. The cholesterol level fell in both fed and fasting animals.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D005215:Fasting; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005502:Food; D007700:Kinetics; D008236:Lypressin / Q000494:pharmacology*; D008297:Male; D051381:Rats; D014280:Triglycerides / Q000097:blood*
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides; D008236:Lypressin; D002784:Cholesterol