Sodium depletion and Fos-immunoreactivity in lamina terminalis.
Rats were either depleted of sodium by treatment with a diuretic or were made hypovolemic by injection of polyethylene glycol (PEG) and their brains were subsequently examined for induction of Fos-like immunoreactivity (FLI). FLI was observed in the lamina terminalis (LT) after both treatments; FLI was observed in the magnocellular neurosecretory hypothalamic areas only after PEG. Implications of these data for brain substrates of sodium appetite are discussed.
D000818:Animals; D001921:Brain / Q000276:immunology*; D005665:Furosemide / Q000494:pharmacology; D006400:Hematocrit; D007031:Hypothalamus / Q000276:immunology / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D011092:Polyethylene Glycols / Q000494:pharmacology; D016760:Proto-Oncogene Proteins c-fos / Q000276:immunology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012964:Sodium / Q000378:metabolism*
D016760:Proto-Oncogene Proteins c-fos; D011092:Polyethylene Glycols; D005665:Furosemide; D012964:Sodium