title: Vitamin E status and response to exercise training.
abstract: Vitamin E is an important intramembrane antioxidant and membrane stabiliser. Over the past 40 years, vitamin E supplementation has been advocated for athletes in the hope of improving performance, minimising exercise-induced muscle damage and maximising recovery. However, there is currently a lack of conclusive evidence that exercise performance or recovery would benefit in any significant way from dietary vitamin E supplementation. Exceeding current recommended intakes of vitamin E even by several orders of magnitude will result in relatively modest increases in tissue or serum vitamin E concentrations. Most evidence suggests that there is no discernible effect of vitamin E supplementation on performance, training effect or rate of postexercise recovery in either recreational or elite athletes. There is very little evidence, particularly involving humans, that exercise or training will significantly alter tissue or serum vitamin E levels. While there is some evidence that certain indices of tissue peroxidation may be reduced following dietary vitamin E supplementation, the physiological and performance consequences in humans of these relatively minor effects are unknown. Although there appears to be little reason for vitamin E supplementation among athletes, it does not appear that the practice of supplementation is harmful.
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance / Q000187:drug effects / Q000502:physiology; D006801:Humans; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology; D018384:Oxidative Stress; D010805:Physical Conditioning, Animal / Q000502:physiology; D013177:Sports / Q000502:physiology; D014810:Vitamin E / Q000494:pharmacology / Q000502:physiology*
chemical_list: D000975:Antioxidants; D014810:Vitamin E