title: [Vitamin D and osteoporosis].
abstract: Vitamin D constitutes a complex endocrine-regulated system, and is both a prohormone for the endogenous synthesis of the active hormone, calcitriol, and a vitamin which may be administered to supply the organism's requirements. No single test or investigation is available for the demonstration of vitamin D deficiency. Both vitamin D intake and ability to synthesise vitamin D decrease with increasing age, and particularly the elderly in institutionalised care are at risk of developing vitamin D deficiency. Iceland excepted, mean daily vitamin D consumption in the Nordic countries is less then 5 micrograms; and in approximately 10-25 per cent of the population, daily intake is less than 2.5 micrograms which is insufficient to maintain an adequate serum calcidiol concentration in individuals unexposed to sunlight. The recommended daily intake of 5 micrograms, currently adopted in the Nordic countries, may be too low-an intake of 10 micrograms is probably necessary to satisfy requirements in the elderly.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000375:Aging / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism; D002112:Calcifediol / Q000097:blood; D006801:Humans; D007326:Institutionalization; D009751:Nutritional Requirements; D010024:Osteoporosis / Q000139:chemically induced / Q000378:metabolism* / Q000517:prevention & control; D012537:Scandinavian and Nordic Countries; D013472:Sunlight; D014807:Vitamin D / Q000096:biosynthesis / Q000378:metabolism*
chemical_list: D000305:Adrenal Cortex Hormones; D014807:Vitamin D; D002112:Calcifediol
vernacular_title: Vitamin D och osteoporos.