title: [Inhibition of lipid peroxidation during emotional-painful stress by ionol and gamma-hydroxybutyric acid].
abstract: UV spectroscopy, polarography and fluorescence of Schiff's bases were used to study the time course of emotional pain stress-induced accumulation of the primary and secondary products of lipoperoxidation (LPO) in different tissues of Wistar rats and to appraise the effect of gamma-hydroxybutyric acid (GHBA) and 4-methyl-2,6-ditretbutylphenol (ionol) on LPO induction. LPO activation was shown to be retained after emotional pain stress for a long enough period of time. This activation may last from 2 to 5 days depending on the organ. Pretreatment with GHBA or ionol completely reverses LPO activation.
mesh_terms: D000818:Animals; D001011:Aorta / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002084:Butylated Hydroxytoluene / Q000627:therapeutic use*; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008297:Male; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010146:Pain / Q000378:metabolism; D051381:Rats; D012545:Schiff Bases / Q000378:metabolism; D013312:Stress, Physiological / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D006885:Hydroxybutyrates; D008054:Lipid Peroxides; D012545:Schiff Bases; D002084:Butylated Hydroxytoluene
vernacular_title: Ingibirovanie ionolom i gamma-oksimaslianoĭ kislotĭ aktivatsii perekisnogo okiosleniia lipidov pri émotsional'no-bolevom stresse.