Spectral evidence of interaction of spice constituents with hepatic microsomal cytochrome P-450.
Spectral evidence has been obtained of the interaction of constituents of two commonly used spices, capsicum and cinnamon, with hepatic microsomal cytochrome P-450. It is proposed that influences of spice constituents on hepatic mixed-function oxidase activities may merit consideration during the investigation of some health-related problems characteristic of, or peculiar to, a given region or cultural group. An example considered relates to the evaluation of certain 'traditional medicines'.
D002212:Capsicum; D055598:Chemical Phenomena; D002621:Chemistry; D002935:Cinnamomum zeylanicum; D003212:Condiments; D003577:Cytochrome P-450 Enzyme System; D008862:Microsomes, Liver / Q000201:enzymology; D010946:Plants, Medicinal; D013056:Spectrophotometry, Ultraviolet
D003577:Cytochrome P-450 Enzyme System