title: Plexus neuropathy following vaccination against tick-borne encephalitis and tetanus due to a sports related altered immune state.
abstract: A 45-year-old female patient who was practising sports on a competition level, developed a plexus neuropathy subsequent to a vaccination against tick-borne encephalitis (TBE) followed by an inoculation of tetanus toxoid six days later. After the TBE vaccination she continued to exercise intensely until symptoms of a neuritis were noticed. Pronounced endurance exercise has been described to alter the composition and function of the immune system. In our patient a decrease of T-helper cells and a significant lowered CD4/CD8 ratio could be detected. The possible link between an altered immune state and post-vaccinal neuropathy is discussed.
mesh_terms: D016516:CD4-CD8 Ratio; D004576:Electromyography; D004675:Encephalitis, Tick-Borne / Q000517:prevention & control*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D018655:Lymphocyte Count; D008875:Middle Aged; D009443:Neuritis / Q000209:etiology* / Q000276:immunology; D012420:Running; D013745:Tetanus Toxoid / Q000009:adverse effects*; D014765:Viral Vaccines / Q000009:adverse effects*
chemical_list: D013745:Tetanus Toxoid; D014765:Viral Vaccines