Ultrastructure of the hypothalamo-neurohypophysial system in rats exposed to lead. II. Neurohypophysis.
Ultrastructure of neurohypophysis was examined in rats allowed to drink for 6 weeks only solution of lead acetate. It was found the increased number of neurosecretory granules in axonal terminals, the signs of granulolysis in Herring bodies and the presence of axonal terminals with atypical, heterogeneous contents. The possible mechanisms of alterations observed in the whole hypothalamoneurohypophysial system affected by lead were discussed.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000648:ultrastructure*; D007855:Lead Poisoning / Q000473:pathology*; D008928:Mitochondria / Q000648:ultrastructure; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar