[The effect of indobufen on platelet function and dialyzer regeneration in patients on hemodialysis].
In 16 patients on chronic haemodialysis treatment the platelet activation and function were studied during 2 weeks antiplatelet therapy with indobufen. Followings tests were made: platelet count, platelet aggregation, platelet factor 3 and 4. Indobufen inhibited platelet function, mainly release of platelet factor 4 and improved dialyser regeneration.
D000328:Adult; D001792:Blood Platelets / Q000187:drug effects*; D005260:Female; D006801:Humans; D054833:Isoindoles; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010654:Phenylbutyrates / Q000494:pharmacology / Q000627:therapeutic use*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D010976:Platelet Count / Q000187:drug effects; D010978:Platelet Factor 4 / Q000378:metabolism; D006435:Renal Dialysis
D054833:Isoindoles; D010654:Phenylbutyrates; D010975:Platelet Aggregation Inhibitors; D010978:Platelet Factor 4; C020371:indobufen
Wpływ indobufenu na czynność krwinek płytkowych i regeneracje dializatorów u chorych hemodializowanych.