[A cytogenetic analysis of the combined action of pesticides and irradiation on human lymphocytes].
The efficiency of the combined action of pesticides and irradiation at the G(o) stage was studied in cultured human lymphocytes. Carbophos (malathion) increased the yield of chromosome and chromatid fragments in irradiated lymphocytes. Herbicide 2,4-D (dichlorophenoxyacetic acid) raised lymphocyte radiosensitivity by increasing the yield of chromosome type aberrations; the radiosensitizing effect of the herbicide decreased as its concentration increased.
D015084:2,4-Dichlorophenoxyacetic Acid / Q000494:pharmacology*; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005720:Gamma Rays; D006540:Herbicides / Q000494:pharmacology*; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects* / Q000528:radiation effects* / Q000648:ultrastructure; D008294:Malathion / Q000494:pharmacology*; D008297:Male; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D016192:Resting Phase, Cell Cycle / Q000187:drug effects / Q000528:radiation effects
D006540:Herbicides; D007306:Insecticides; D011838:Radiation-Sensitizing Agents; D015084:2,4-Dichlorophenoxyacetic Acid; D008294:Malathion
Tsitogeneticheskiĭ analiz sochetannogo deĭstviia pestitsidov i oblucheniia na limfotsity cheloveka.