title: Delayed onset of fatal basilar thrombotic embolus after whiplash injury.
abstract: BACKGROUND
  Whiplash injuries are generally seen after rear-end rather than frontal car collisions. Previous reports have documented death up to 8 days after serious whiplash injury. We report a case of lethal basilar thrombotic embolus that occurred 2 months after the patient's injury in a collision.
  
  
  METHODS
  After whiplash trauma in a car accident, a 50-year-old taxi driver suffered from headache and episodic visual disturbances. Two months after the accident he suddenly lost consciousness and was admitted to the hospital. A CT scan performed at that time was indicative of basilar thrombosis. The patient died 3 days later. The autopsy revealed a thrombosis in the right vertebral artery and a thrombotic embolus in the basilar artery. Microscopically, a lesion of the right vertebral artery was found at the level of the atlantoaxial joint.
  
  
  CONCLUSIONS
  We conclude that the whiplash injury caused a lesion of the right vertebral artery, leading to repeated transient ischemic attacks and finally to a fatal basilar thrombotic embolus. We suggest that in patients with disturbances of the vertebrobasilar circulation, attention should be paid to occurrence of neck trauma in the preceding 3 months. Further, anticoagulant therapy should particularly be considered in patients who after suffering neck injuries develop signs of transient ischemic attacks with origin from the posterior cerebral circulation.
mesh_terms: D001488:Basilar Artery / Q000473:pathology*; D002544:Cerebral Infarction / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D013923:Thromboembolism / Q000209:etiology*; D014911:Whiplash Injuries / Q000150:complications*