title: [Optical and tactile hallucinosis as clinical onset of Creutzfeld-Jakob disease].
abstract: A patient suffering from Creutzfeld-Jakob disease (CJD) complained of optical hallucinations, followed by feelings of persecution. Clinical, encephalographic and neuropathological findings pointed towards a focalized beginning of the disease process in the right frontal and temporal lobe. The hypothesized further spread of the infectious agent, as indicated by electroencephalographic and neuropathological findings, was accompanied by periacute manifestation of dementia and an irreversible disturbance of vigilance. The diagnosis of CJE can be especially difficult in the early stages of the disease, with dementia, myocloni and typical electroencephalographic findings still absent.
mesh_terms: D000368:Aged; D001931:Brain Mapping; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006212:Hallucinations / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009483:Neuropsychological Tests; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology; D014110:Touch / Q000502:physiology; D014796:Visual Perception / Q000502:physiology
vernacular_title: Optische und taktile Halluzinose als klinischer Beginn einer Creutzfeld-Jakob-Erkrankung.