[A bank of protein family images Prof-Image for rapid determination of possible functions of random amino acid sequences].
A bank of images of protein families (PROF IMAGE bank) is developed using early published method and amino acid sequences of 24-th release SWISS-PROT bank (27752 sequences). The method relies on physical-chemical and structural properties of amino acids and on the choice of fragments of protein families for the most discriminate distinction of amino acid sequences of a family from representatives of other families or random sequences. Specifications of the algorithms of building the images, principles of amino acid sequences selection to form protein families, the structure of the bank, and characteristics of images of 163 protein families are described. The data are illustrated by the image of alpha-interferon precursors family. The results of the images comparison with all proteins of the SWISS-PROT bank and ways to use the PROF IMAGE bank for determination of possible functions of amino acid sequences are discussed.
D000465:Algorithms; D000595:Amino Acid Sequence; D007256:Information Systems; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D013329:Structure-Activity Relationship
D011506:Proteins
Bank obrazov belkovykh semeĭstv Prof-Image dlia bystrogo opredeleniia bozmozhnykh funktsiĭ proizvol'nykh aminokislotnykh posledovatel'nosteĭ.