Probable Creutzfeldt-Jakob disease after a cadaveric dural graft.
A 26-year old female who had received a cervical cadaveric dural graft 7 years earlier developed psychotic behavior and generalized myoclonic jerks. Following rapid deterioration and appearance of high-charge sharp periodic waves on electroencephalography she died within two months. We believe that this patient is the first German who acquired Creutzfeldt-Jakob disease by dural implant.
D000328:Adult; D001254:Astrocytoma / Q000601:surgery; D002102:Cadaver; D007562:Creutzfeldt-Jakob Syndrome / Q000209:etiology / Q000635:transmission*; D018562:Disease Transmission, Infectious; D004388:Dura Mater / Q000637:transplantation*; D004569:Electroencephalography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D012086:Reoperation; D013120:Spinal Cord Neoplasms / Q000601:surgery; D016378:Tissue Transplantation / Q000009:adverse effects