title: Phosphonothrixin, a novel herbicidal antibiotic produced by Saccharothrix sp. ST-888. I. Taxonomy, fermentation, isolation and biological properties.
abstract: A novel herbicidal compound, phosphonothrixin, was found in the fermentation broth of Saccharothrix sp. ST-888 cultured on a vegetable juice medium. The compound exhibiting acidic and hydrophilic properties was obtained when the fermentation broth of ST-888 was subjected to ion exchange chromatography, gel filtration chromatography and ion-pair chromatography. Phosphonothrixin significantly inhibited germination of gramineous and broadleaf weeds. Foliar application of this antibiotic gave rise to chlorosis in all of the plants tested.
mesh_terms: D000192:Actinomycetales / Q000145:classification; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D005285:Fermentation; D006540:Herbicides / Q000302:isolation & purification* / Q000494:pharmacology; D063065:Organophosphonates / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D006540:Herbicides; D063065:Organophosphonates; C096940:phosphonothrixin