title: [Neuroblastoma: diagnosis and therapy].
abstract: Prognosis of neuroblastoma is primarily dependent on the stage of disease. While stages 1 to 3 show a survival rate of 94 to 66%, stage 4 has a survival rate below 20%. The most important prognostic factor is the extent of disease. Age, LDH, resectability of primary tumor, cytologic and molecular parameters are defined to have a prognostic impact as well. A stage- and risk-adapted therapy of neuroblastoma needs a thorough assessment of all these factors.
mesh_terms: D000293:Adolescent; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D004273:DNA, Neoplasm / Q000235:genetics; D006801:Humans; D007223:Infant; D009447:Neuroblastoma / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D011003:Ploidies; D011379:Prognosis; D012307:Risk Factors
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Neuroblastom: Diagnostik und Therapie.