[Correlation analysis of lipids and apolipoproteins in plasma HDL, LDL and VLDL of normal subjects and endogenous hypertriglyceridemics].
The linear correlation and multiple stepwise regression analysis of lipids and apolipoproteins in plasma, HDL, LDL and VLDL of 20 normal subjects and 20 patients with endogenous hypertriglyceridemia was made. The result of simple factor analysis showed that there was a positive correlation of TG and VLDL TG with apoC II, C III, E, LDL apoB100 and VLDL apoC II, C III, E, B100; and a negative correlation with HDL apoA I. HDL-C was related positively with apoA I, HDL apoA I, C III and negatively with apoC III, E, LDL apoB100 and VLDL apoB100, C II, C III, E. TC was correlated positively with apoB100 and LDL apoB100. The result of multiple factor analysis showed that apoC III, E, B100/A I, VLDL apoC III and HDL apo C II, E, C II/C III, among 20 factors, were main factors which were related with TG. Apo C III, VLDL apoC III and LDL apoB100 were main factors which affected VLDL TG. ApoB100, and C II were main apolipoproteins which were related with TC; while the main apolipoproteins which affected HDL-C were apoA I, HDL apoA I, C II, VLDL apoE, HDL apoA II, the significance of the results is discussed.
D001053:Apolipoproteins / Q000097:blood*; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D014280:Triglycerides / Q000097:blood*
D001053:Apolipoproteins; D008055:Lipids; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides