Stability of remission during tricyclic antidepressant continuation therapy for dysthymia.
Sixty-four of 73 patients with DSM-III-R dysthymia who responded to short-term treatment with tricyclic antidepressants (TCAs) completed 16 to 20 weeks of continuation therapy on the same medication. Forty-one of 46 full remitters remained in full remission, while 5 became partial remitters during the continuation treatment. Of 18 partial remitters, 8 became fully remitted, 8 remained partial remitters, and 2 relapsed. Thus the stability of remission in dysthymic subjects treated with TCA seems quite favorable during continuation treatment.
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome
D000929:Antidepressive Agents, Tricyclic