Long-term potentiation at low temperature is stronger in hippocampal slices from hibernating Turkish hamsters compared to warm-acclimated hamsters and rats.
Tetanus-induced long-term potentiation (LTP) of population action potentials at 22 degrees C was investigated in area CA1 of hippocampal slices prepared from hibernating (HH) and warm-acclimated Turkish hamsters (WH) and rats. LTP elicited at this temperature was significantly stronger in HH slices compared to WH and rat slices. Hibernation-related improvement of the ability to develop long-lasting enhancement of synaptic transmission at low temperatures is interpreted as supporting hippocampal function during arousal from hibernation.
D000064:Acclimatization; D000818:Animals; D001833:Body Temperature Regulation; D006224:Cricetinae; D006624:Hippocampus / Q000502:physiology*; D017774:Long-Term Potentiation; D051381:Rats; D017208:Rats, Wistar; D009435:Synaptic Transmission / Q000502:physiology; D013997:Time Factors