[The induction of lipid peroxidation in human brain glial tumors].
Tissue examinations of glial tumors in the human brain revealed that therein lipid peroxidation could be induced by using bivalent iron salts, which is indicated by higher malonic dialdehyde levels. The authors have demonstrated that the glioma tissue levels of iron were statistically lower than those in the brain tissue. The induction in tumor tissue does not depend upon the degree of its malignancy, but it significantly differs from this parameter in the rabbit brain tissue. The induction of lipid peroxidation processes is accompanied by a lower cumulative antioxidative activity. The findings open new prospects for affecting tumor growth.
D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000737:chemistry / Q000378:metabolism*; D005910:Glioma / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000378:metabolism; D011817:Rabbits
D000975:Antioxidants; D008315:Malondialdehyde; D007501:Iron
Induktsiia perekisnogo okisleniia lipidov v glial'nykh opukholiakh golovnogo mozga cheloveka.