title: Effect of alcohol on body core temperature during cold-water immersion.
abstract: This study investigates the influence of alcohol on body core temperature during cold-water immersion in human volunteers. In this randomised, double-blind, placebo-controlled crossover trial, 8 healthy male volunteers were randomised to drink 1 litre of beverage containing 50 g alcohol or placebo before 20 degrees C cold-water immersion for 1 hour. Body core temperature was measured before cooling and after 1 hour of immersion with an infrared ear thermometer. After a 1-week interval subjects crossed to the other study branch. In the placebo test, mean temperature decreased after immersion by 0.66 degrees C; after the alcohol mean temperature decreased by 1.0 degrees C (mean difference 0.34, 95% CI 0.14-0.53, P = 0.002).
mesh_terms: D000328:Adult; D001831:Body Temperature / Q000187:drug effects*; D003080:Cold Temperature; D018592:Cross-Over Studies; D004311:Double-Blind Method; D000431:Ethanol / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007101:Immersion; D008297:Male
chemical_list: D000431:Ethanol