title: Determination of itraconazole and its metabolite in plasma using SPE-HPLC.
abstract: A SPE-HPLC procedure for the determination of itraconazole and its metabolite has been developed. The method was shown to be suitable for routine therapeutic monitoring in leukemic patients.
mesh_terms: D000935:Antifungal Agents / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D017964:Itraconazole / Q000031:analogs & derivatives / Q000097:blood*; D007938:Leukemia / Q000097:blood*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000935:Antifungal Agents; C084794:hydroxyitraconazole; D017964:Itraconazole