title: Biocatalytic oxidation of polycyclic aromatic hydrocarbons by hemoglobin and hydrogen peroxide.
abstract: Hemoglobin is able to oxidize polycyclic aromatic hydrocarbons, PAH's, in presence of hydrogen peroxide. Among 12 aromatic compounds tested, six were oxidized; anthracene, carbazole, dibenzothiophene, fluorene, 9-hexylanthracene and pyrene. The products were identified as aromatic ketones and sulfoxides. Effect of organic solvent concentration and hemoglobin stability were determined.
mesh_terms: D000097:Acetonitriles; D002384:Catalysis; D002849:Chromatography, Gas; D004355:Drug Stability; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide; D007700:Kinetics; D010084:Oxidation-Reduction; D011083:Polycyclic Compounds / Q000737:chemistry* / Q000378:metabolism*; D012997:Solvents; D013329:Structure-Activity Relationship
chemical_list: D000097:Acetonitriles; D006454:Hemoglobins; D011083:Polycyclic Compounds; D012997:Solvents; D006861:Hydrogen Peroxide; C032159:acetonitrile