Cerebral hemorrhage in alloimmune thrombocytopenia.
Intracranial hemorrhages are rare in term infants. We describe such an infant born with multiple foci of intraparenchymal hemorrhage in various stages of maturation, caused by maternal platelet-specific anti-PlA1 antibodies that were delivered transplacentally to the developing fetus.
D001792:Blood Platelets / Q000276:immunology*; D002543:Cerebral Hemorrhage / Q000209:etiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000276:immunology*; D008431:Maternal-Fetal Exchange / Q000276:immunology*; D011247:Pregnancy; D013921:Thrombocytopenia / Q000150:complications / Q000276:immunology*
D007519:Isoantigens