title: Effect of milk and fermented milk on iron absorption in ileostomy subjects.
abstract: This study was undertaken to determine whether milk with its high calcium content adversely affects the absorption of nonheme iron from the diet as greatly as single-meal studies indicate. Nine ileostomy subjects ate a low-fiber, low-phytate diet for 8 consecutive weeks. During the first and eight weeks they drank a 250-mL soft drink with three main meals and an evening snack each day (0.16 g Ca/d). During the two intervening 3-wk periods, they drank the same amount of low-fat milk or fermented low-fat milk (Verum; Hälsofil, Norrmejerier, Umeä, Sweden) according to a formally randomized crossover design (1.4 g Ca/d). During the last 2 d in each of the four periods, apparent iron absorption (balance) from a test diet together with that period's beverage was measured and the plasma ferritin concentration was determined. There was no decrease in apparent iron absorption during the milk diet periods.
mesh_terms: D000328:Adult; D000818:Animals; D002136:Calcium, Dietary / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*; D018592:Cross-Over Studies; D004032:Diet / Q000592:standards; D005260:Female; D005285:Fermentation; D006801:Humans; D007081:Ileostomy; D007295:Inositol Phosphates / Q000032:analysis; D007408:Intestinal Absorption / Q000187:drug effects* / Q000502:physiology; D007501:Iron / Q000032:analysis / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000737:chemistry / Q000378:metabolism / Q000592:standards*; D010833:Phytic Acid / Q000008:administration & dosage / Q000032:analysis
chemical_list: D002136:Calcium, Dietary; D007295:Inositol Phosphates; D010833:Phytic Acid; D007501:Iron