title: Elasticity imaging for early detection of renal pathology.
abstract: Early detection of renal pathology may be possible with elasticity imaging. This hypothesis was experimentally tested by quantitatively imaging internal mechanical strain due to surface deformations in an in vitro animal model of nephritis. Preliminary data support the hypothesis that kidney elasticity changes with renal damage and concomitant scarring before problems are detectable by traditional diagnostic techniques such as laboratory measurements of renal function.
mesh_terms: D000818:Animals; D004548:Elasticity; D005921:Glomerulonephritis / Q000000981:diagnostic imaging; D006041:Goats; D066298:In Vitro Techniques; D007668:Kidney / Q000000981:diagnostic imaging* / Q000473:pathology; D019047:Phantoms, Imaging; D011817:Rabbits; D014463:Ultrasonography