title: [Efficacy and tolerance of azithromycin in respiratory tract infections in children].
abstract: This study was carried out to determine the clinical efficacy and the clinical safety of azithromycin in a group of children with acute respiratory tract infections. The study involved 82 children treated with a single daily 10 mg/kg dose of azithromycin for three consecutive days. 7 days later, the overall clinical response was 100% (cure and improvement): bacteriological cure was achieved in 97.5% of the patients treated. Recurrences were never observed. Side effects not requiring interruption of therapy were observed in 3 patients (3.6%). The side effects were gastrointestinal disturbances. In conclusion azithromycin showed a remarkably clinical efficacy for treatment of acute respiratory infections in children. Tolerability and therapeutic compliance were excellent.
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D017963:Azithromycin / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D001886:Bordetella pertussis / Q000187:drug effects / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D004361:Drug Tolerance; D005260:Female; D006190:Haemophilus / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D008297:Male; D001936:Moraxella catarrhalis / Q000187:drug effects / Q000302:isolation & purification; D009177:Mycoplasma pneumoniae / Q000187:drug effects / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000382:microbiology; D012189:Retrospective Studies; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin
vernacular_title: Efficacia e tollerabilità dell'azitromicina nelle infezioni respiratorie del bambino.