[Some aspects of epidemiology in insulin-dependent diabetes mellitus (IDDM) (II)].
Seasonality is a characteristic feature of IDDM incidence. The lowest incidence is observed in summer, whereas the highest in winter/autumn. The risk of IDDM increases in children with independently: breast feeding shorter then 3 months, feeding with cow's milk instead of breast feeding, early introducing of solid diet in babies, or high consumption of cow's milk in later years. Children with new onset IDDM have elevated levels of the antibodies against cow's milk proteins and beta-lactoglobulin. It has been proved that there is a connection with HLA DQalfaArg52 i DQbeta-Asp57 and polymorphic region of insulin gene, and the IDDM susceptibility.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D001483:Base Sequence; D001942:Breast Feeding; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology* / Q000276:immunology; D004198:Disease Susceptibility; D005060:Europe / Q000453:epidemiology; D006683:HLA-DQ Antigens / Q000235:genetics; D006801:Humans; D015994:Incidence; D007225:Infant Food; D007231:Infant, Newborn; D007328:Insulin / Q000235:genetics; D007782:Lactoglobulins / Q000276:immunology; D008892:Milk / Q000276:immunology; D008969:Molecular Sequence Data; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors; D012621:Seasons
D000906:Antibodies; D006683:HLA-DQ Antigens; D007328:Insulin; D007782:Lactoglobulins
Niektóre kierunki badań w epidemiologii cukrzycy insulinozaleznej (IDDM) (II).