title: 4,5-Dihydro-3-(2-pyrazinyl)naphtho[1,2-c]pyrazole: a potent and selective inhibitor of steroid-17 alpha-hydroxylase-C17,20-lyase (P450 17).
mesh_terms: D000368:Aged; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000188:drug therapy; D011719:Pyrazines / Q000494:pharmacology*; D011720:Pyrazoles / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors* / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: C096991:4,5-dihydro-3-(2-pyrazinyl)naphtho(1,2-c)pyrazole; D004791:Enzyme Inhibitors; D011719:Pyrazines; D011720:Pyrazoles; C031280:pyrazole; D013254:Steroid 17-alpha-Hydroxylase