A case of an exceptionally high level of urinary-4-hydroxyproline containing polypeptides.
The determination of total urinary-4-hydroxyproline in an adolescent showed a very high excretion of hydroxyproline containing peptides: 26.2 mmol/24 h. Estimation of total urinary 3-hydroxyproline and peptide fractionation on Biogel P 2 demonstrated unusual features. Such cases are of great interest for structural studies of the urinary polypeptides and understanding of collagen catabolism.
D000293:Adolescent; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003094:Collagen / Q000378:metabolism; D006801:Humans; D006909:Hydroxyproline / Q000652:urine*; D008297:Male; D010455:Peptides / Q000652:urine*; D012445:Sacrococcygeal Region; D013125:Spinal Neoplasms / Q000378:metabolism; D013724:Teratoma / Q000378:metabolism
D010455:Peptides; D003094:Collagen; D006909:Hydroxyproline