title: Incidence of the gene mutation causal for rod-cone dysplasia type 1 in Irish setters in the UK.
abstract: A survey to establish the UK prevalence of the gene mutation causing the rod-cone dysplasia type one (rcd1) form of generalised progressive retinal atrophy (gPRA) in Irish setters was carried out. The dogs were selected by members of two Irish setter breed societies to provide examples from most of the main breeding lines in the UK. A total of 210 Irish setters were tested and one bitch was found to be a carrier of the rcd1 mutation. These results show that although a confirmed case of rcd1 has not been reported in Irish setters in the UK for over a decade the gene is still present in the gene pool.
mesh_terms: D000818:Animals; D001483:Base Sequence; D017931:DNA Primers; D004262:DNA Restriction Enzymes; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D009154:Mutation; D016133:Polymerase Chain Reaction / Q000662:veterinary; D015792:Retinal Dysplasia / Q000235:genetics / Q000662:veterinary*; D006113:United Kingdom
chemical_list: D017931:DNA Primers; D004262:DNA Restriction Enzymes