Lymphoplasmacyte-rich meningioma in a child. Case report.
A rare case of lymphoplasmacyte-rich meningioma observed in a young girl is reported. The first clinical manifestations of the disease were seizures. Neuroradiological images favored the existence of a meningioma. Abnormalities in the patient's blood chemistry, principally including hypergammaglobulinemia and inflammatory syndrome, were associated with the disease. The tumor was histologically confirmed as meningioma with massive infiltrates of type B lymphocytes. The pathophysiology of the conspicuous lymphoplasmacyte infiltrates, responsible for peripheral blood abnormalities, has remained poorly understood. Alternative diagnostic hypotheses of masses that mimic this type of meningioma are discussed.
D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation; D008214:Lymphocytes / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D012640:Seizures / Q000209:etiology