Studies on the inhibitory effects of some acridone alkaloids on Epstein-Barr virus activation.
Twenty-five acridone alkaloids from Citrus plants were examined for their inhibitory effects on Epstein-Barr virus activation by a short-term in vitro assay. 5-Hydroxynoracronycine (20) and acrimarine-F (25) showed remarkable inhibitory effects.
D000166:Acridines / Q000302:isolation & purification / Q000494:pharmacology*; D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002460:Cell Line; D002957:Citrus; D004854:Herpesvirus 4, Human / Q000187:drug effects / Q000254:growth & development*; D006801:Humans; D018517:Plant Roots; D013329:Structure-Activity Relationship; D014775:Virus Activation / Q000187:drug effects*
D000166:Acridines; D000470:Alkaloids; D000998:Antiviral Agents