title: [Cardiocirculatory stability and early extubation in patients undergoing thoracic surgery with propofol as the single anesthetic agent].
abstract: OBJECTIVE
  To determine the efficiency of total intravenous anesthesia technique (TIVA) using propofol on maintaining cardio-circulatory stability and rapid recovery time in patients undergoing thoracotomy.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  University General Hospital in Spain.
  
  
  METHODS
  Twelve patients, undergoing elective thoracic surgery, including lung resection with one-lung ventilation with more than 120 minutes of anesthetic time.
  
  
  METHODS
  ECG, blood pressure (BP), heart rate (HR), pulse oximetry (SpO2), end tidal CO2 (ETCO2) and muscular relaxation with Relaxograph were monitored. Anesthesia was performed with propofol 1.5-2.5 mg/kg i.v. and maintained with continuous propofol infusion 4 +/- 1.4 mg/kg/h. Fentanyl, 10 mg i.v., was administered in bolus. After succinylcholine 1 mg/kg i.v. or atracurium 0.5 mg/kg i.v., trachea was intubated with a double-lumen tube or a standard cuffed endotracheal tube. The patients were ventilated with air-oxygen mixture. Maintenance of muscular relaxation was obtained with atracurium 0.2 mg/kg i.v.
  
  
  RESULTS
  No significative differences were registered in the values of heart rate, SpO2, ETCO2 and between intraoperative blood pressure and the postextubation blood pressure values. Recovery time, from discontinuation of the propofol until postoperative extubation, was 8.25 +/- 4.8 minutes.
  
  
  CONCLUSIONS
  Performing a TIVA with propofol good cardiocirculatory stability was obtained. Continuous monitoring of relaxation, graphically recorded, knowing the bolus rate of muscle relaxant, allows us to antagonize it totally, facilitating patient recovery and its early postoperative extubation.
mesh_terms: D000328:Adult; D000368:Aged; D018686:Anesthetics, Intravenous; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D015742:Propofol; D013908:Thoracotomy; D013997:Time Factors
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol
vernacular_title: Stabilità cardiocircolatoria ed estubazione precoce nei pazienti sottoposti a chirurgia toracica utilizzando propofol come agente anestetico unico.