title: [The cytogenetic analysis of the adaptive response in the lymphocytes of donors living in areas with different levels of radioactive contamination].
abstract: The adaptive response was studied in peripheral lymphocytes of healthy donors residing at territories with various levels of radioactive contamination. For donors from a clean territory (the town of Obninsk), the adaptive response depended on the cell cycle stage at which lymphocytes had been exposed to adaptive and challenge doses. The most expressed adaptive response was observed if lymphocytes had been exposed to the adaptive dose 0.05 Gy at G0 or G1 stage and to the challenge dose 0.5 Gy at G2 stage. Lymphocytes of donors from a contaminated territory (the town of Novozybkov) did not show an adaptive response in the conditions described above.
mesh_terms: D000222:Adaptation, Physiological / Q000528:radiation effects*; D001782:Blood Donors; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics*; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D005720:Gamma Rays; D006801:Humans; D008214:Lymphocytes / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D011210:Power Plants; D018788:Radioactive Hazard Release; D011868:Radioisotopes / Q000009:adverse effects*; D012426:Russia; D014455:Ukraine
chemical_list: D011868:Radioisotopes
vernacular_title: Tsitogeneticheskiĭ analiz adaptivnogo otveta u limfotsitov donorov, prozhivaiushchikh na territoriiakh s razlichnym urovnem radioaktivnogo zagriazneniia.