title: Is bronchial asthma a pancreatic disease?
abstract: Bronchial asthma and diabetes mellitus seldom occur in the same patient. The exact mechanism of this mutual exclusion is still unknown and its elucidation can make clear the physiopathology of both diseases. Clinical and experimental evidences suggest that insulin is a proinflammatory hormone and glucagon an antiinflammatory and a bronchodilator one. We hypothesize that the relationship between plasma insulin and glucagon may play an important role in bronchial asthma.
mesh_terms: D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000503:physiopathology*; D005934:Glucagon / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000378:metabolism / Q000502:physiology* / Q000627:therapeutic use; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism; D010179:Pancreas / Q000187:drug effects / Q000503:physiopathology; D010182:Pancreatic Diseases / Q000503:physiopathology*
chemical_list: D018927:Anti-Asthmatic Agents; D007328:Insulin; D005934:Glucagon