[The use of the FISH method for reconstructing the absorbed doses received by participants in the clean-up of the accident at the Chernobyl Atomic Electric Power Station].
The frequency of stable translocations using two-color fluorescence in situ hybridisation (FISH) were determined in peripheral blood lymphocytes of 20 persons who took part in liquidation of the Chernobyl accident and of 11 persons of control group. The individual doses for all patients were estimated from a calibration dose-response curve for stable translocation. The doses estimated by our cytogenetic data not always coincided with official dosimetric data. The possibility of using FISH for dose reconstruction of past radiation exposure was discussed.
D000328:Adult; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008214:Lymphocytes / Q000528:radiation effects / Q000648:ultrastructure; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D011210:Power Plants; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D014455:Ukraine
Ispol'zovanie FISH-metoda dlia rekonstruktsii pogloshchennykh doz, poluchennykh uchastnikami likvidatsii avarii na Chernobyl'skoĭ AES.