Mandibular reconstruction by secondary reimplantation of resected segments: a preliminary report.
This paper presents a new method of reconstructing the mandible after ablative surgery for cancer. This method uses autogenous grafts consisting of the respected part of the mandible, which is hollowed out, defatted in chloroform/methanol, sterilized with ethylene oxide, irradiated with beta-radiation (dose 25 kGy), and stored for 7-10 months. At reimplantation, they were filled with compressed, autogenous, particulate cancellous bone. All grafts took, and four of six host-graft junctions healed.
D000368:Aged; D001610:Beta Particles; D016025:Bone Transplantation / Q000379:methods* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D002725:Chloroform; D005027:Ethylene Oxide; D005500:Follow-Up Studies; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008339:Mandibular Neoplasms / Q000601:surgery; D000432:Methanol; D008875:Middle Aged; D011829:Radiation Dosage; D012092:Replantation; D012997:Solvents; D013242:Sterilization; D014021:Tissue Preservation; D014182:Transplantation, Autologous
D012997:Solvents; D002725:Chloroform; D005027:Ethylene Oxide; D000432:Methanol