title: Surgical management of primary bone sarcomas.
abstract: Effective chemotherapy regimens have changed the nature and scope of surgical management of primary sarcomas of bone. Limb-salvage surgical procedures are performed in the majority of patients without a significantly increased risk of local tumor relapse. Advances in technology have expanded the options available for skeletal reconstruction. End-result analyses have helped refine the application of this technology to maximize function. Further advances are necessary to maintain function in the long term.
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical; D001174:Arthrodesis; D001178:Arthroplasty; D001186:Artificial Limbs; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D016025:Bone Transplantation; D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D005121:Extremities / Q000254:growth & development / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009985:Orthopedics / Q000379:methods*; D010388:Pelvis / Q000601:surgery; D012509:Sarcoma / Q000188:drug therapy / Q000601:surgery*