title: Fatty acid composition of palatal tissue from denture stomatitis patients.
abstract: Palatal biopsy specimens were obtained from patients with denture stomatitis. The fatty acids were extracted from the tissue, then separated, identified, and quantified by a gas-chromatographic technique. The sensitivity of this method enabled analyses of specimens with a wet weight of less than 1 mg. The concentration of the fatty acids C16:1 (n-7) and C24:1 (n-9) differed significantly between samples from hyperplastic and clinically healthy tissue in the denture stomatitis patients. By comparing specimens from denture stomatitis patients and non-denture subjects, the concentration of seven fatty acids, two saturated and five unsaturated, was found to be significantly different. A multivariate data-analytical method distinguished between the fatty acid composition in specimens from denture stomatitis patients and from non-denture subjects.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D002849:Chromatography, Gas; D003819:Denture Bases / Q000009:adverse effects*; D004952:Esters; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008297:Male; D013058:Mass Spectrometry; D008768:Methylmethacrylates / Q000009:adverse effects / Q000737:chemistry; D008875:Middle Aged; D009061:Mouth Mucosa / Q000737:chemistry*; D015999:Multivariate Analysis; D010159:Palate; D018709:Statistics, Nonparametric; D013282:Stomatitis, Denture / Q000209:etiology / Q000378:metabolism* / Q000473:pathology
chemical_list: D004952:Esters; D005227:Fatty Acids; D008768:Methylmethacrylates