[The effect of natural immunomodulators on the lymphocytic natural killer activity in patients with malignant lymphoproliferative diseases].
The conducted investigations showed an apparent immunomodulating action of the studied natural preparations on natural resistance of patients with malignant lymphomas. The modulation effect was the greatest in patients taking esberitox during remission and while receiving radiotherapy. Administration of Ney Tumorin to patients with lymphogranulomatosis during remission appeared to be associated with substantial increase in the content of large granular lymphocytes and level of natural killer activity (almost two--fold) immediately after the end of the treatment and this tendency was to be still seen one--two months later. Pirogenal had marked stimulatory effect on natural resistance of patients with granulomatosis in the postradiation period. The studied preparations were not associated with side effects. General condition improved after their administration, as per subjective experience.
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D008070:Lipopolysaccharides / Q000008:administration & dosage; D008232:Lymphoproliferative Disorders / Q000188:drug therapy* / Q000276:immunology; D010936:Plant Extracts / Q000008:administration & dosage; D012008:Recurrence; D013607:Tablets; D013997:Time Factors
D000276:Adjuvants, Immunologic; D008070:Lipopolysaccharides; D010936:Plant Extracts; D013607:Tablets; C009136:pyrogenal; C026057:Esberitox
Vliianie prirodnykh immunomoduliatorov na estestvennuiu killernuiu aktivnost' limfotsitov bol'nykh zlokachestvennymi limfoproliferativnymi zabolevaniiami.