The lipid peroxidation products and the enzymes of antioxidant system in patients with diabetes mellitus.
The lipid peroxidation product level (conjugated dienes, malonyldialdehyde) as well as superoxide dismutase and glutathione peroxidase activity in diabetic patients were studied. It was found that diabetes mellitus is accompanied by an increase in serum conjugated diene and malonyldialdehyde level as well as by an increased malonyldialdehyde concentration in red blood cells. No changes in erythrocyte superoxide and glutathione peroxidase activity in diabetic patients were found. There were also no differences between diabetic patients with poor and good metabolic control in any of the examined parameters.
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D013482:Superoxide Dismutase / Q000097:blood
D000975:Antioxidants; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase