Age-dependent changes in the beta-endorphin content of discrete rat brain nuclei.
Concentrations of beta-endorphin were measured by radioimmunoassay in discrete brain nuclei of young (3 months) and old (24 months) rats. The beta-endorphin content of all major structures known to contain this peptide with the exception of the eminence, is reduced (50.3 +/- 2.8% of control) in old rats.
D000375:Aging; D000818:Animals; D001921:Brain / Q000378:metabolism*; D004723:Endorphins / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D008297:Male; D008526:Medulla Oblongata / Q000378:metabolism; D011388:Prolactin / Q000097:blood; D051381:Rats
D004723:Endorphins; D011388:Prolactin