Identification of the major capsid protein gene of human herpesvirus 7.
Two human herpesvirus 6 (HHV-6) open reading frames were identified with significant amino acid similarity to UL86 (major capsid protein, MCP) and UL85 of human cytomegalovirus (HCMV) in human herpesvirus 7 (HHV-7) genes. The predicted lengths of the complete HHV-7 MCP and the HCMV-UL85 open reading frames were 1344 and 293 amino acids with estimated molecular weights of approximately 153 and 33 kDa, respectively. Computer analysis showed that the amino acid of HHV-7 MCP was 61% identical to the MCP of HHV-6 variants A and B, 28% to HCMV. These results suggest that HHV-7 is more closely related to HHV-6 than to HCMV.
D000328:Adult; D000818:Animals; D001483:Base Sequence; D002213:Capsid / Q000235:genetics*; D002478:Cells, Cultured; D003587:Cytomegalovirus / Q000145:classification / Q000235:genetics; D017931:DNA Primers; D006564:Herpesviridae / Q000235:genetics / Q000378:metabolism; D015654:Herpesvirus 6, Human / Q000145:classification / Q000235:genetics; D016199:Herpesvirus 7, Human / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D012689:Sequence Homology, Nucleic Acid
D017931:DNA Primers