[Lipid transport in blood from the protein chemistry viewpoint].
In agreement with the protein biochemistry principles apolipoprotein is considered to the only protein which: 1) forms protein-lipid complex (PLC) based on one lipid grade; 2) determines its functional significance; 3) causes the development of dyslipidemia at genetic disorder of quantitative and qualitative protein composition. The lipid transport in blood flow is based on high functional specifics of each of apoproteins; each apoprotein forms functionally separate PLC; each PLC has got one protein-vector; each protein-vector interacts with only one receptor. The basis of united cycle functioning in lipid transport is the difference of primary apoprotein structure. Cholesterol conducts an auxiliary function in triglyceride transport providing circulation in functional cycle. The lipid transport in blood flow is based first of all on protein chemistry principles and secondary--on lipidology principles.
D001053:Apolipoproteins / Q000097:blood / Q000378:metabolism; D001161:Arteriosclerosis / Q000209:etiology; D001692:Biological Transport; D001798:Blood Proteins / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D006801:Humans; D006949:Hyperlipidemias / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood / Q000378:metabolism; D014280:Triglycerides / Q000097:blood / Q000378:metabolism
D001053:Apolipoproteins; D001798:Blood Proteins; D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol
Transport lipidov v krovotoke s pozitsiĭ khimii belka.