title: Laparoscopic aortofemoral bypass. Initial experience in an animal model.
abstract: OBJECTIVE
  The study objective was to evaluate the feasibility of laparoscopic aortofemoral bypass in a porcine model.
  
  
  BACKGROUND
  Laparoscopic techniques have been applied to numerous general and thoracic surgical procedures. Their application to vascular surgery has been virtually nonexistent. Open surgery for aortoiliac occlusive disease is accompanied by significant morbidity rates, and minimally invasive procedures have the disadvantage of reduced patency rates. Laparoscopic aortofemoral replacement has the theoretical advantage of long-term patency with reduced postoperative complications.
  
  
  METHODS
  Between January and September 1993, laparoscopic surgery was performed on 16 pigs: 6 underwent transperitoneal laparoscopic aortic dissection and vessel control alone; 7 underwent complete transperitoneal laparoscopic aortofemoral bypass; and 3 underwent a retroperitoneal approach. The aortic anastomosis was performed using a combination of sutures and titanium clips in an end-to-side fashion in five pigs, and a custom-made nonsutured graft was secured with use of an end-to-end method in five pigs. Femoral anastomoses were performed with the standard open technique.
  
  
  RESULTS
  Technical success was achieved in all 10 animals and with no major complications. Mean blood loss was 20 ml (range, 5-50 ml), and mean operative time was 2.45 hours (range, 2-4 hrs). On aortic-clamp release, 2 of the end-to-side anastomoses required additional sutures to stop bleeding between oversized staples, and 2 of the end-to-end anastomoses required additional ties to reinforce loose ties. All 10 grafts and anastomoses were patent and free of leaks after completion of the procedure.
  
  
  CONCLUSIONS
  Laparoscopic aortofemoral bypass is technically feasible in a porcine model. Further experimental work with new instrumentation and technical refinement will make laparoscopic surgery feasible for the treatment of vascular disease in humans.
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery*; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D010535:Laparoscopy; D013552:Swine; D014656:Vascular Surgical Procedures / Q000379:methods