[Pathogenetic criteria for evaluating the virulence of tick-borne encephalitis strains isolated in the southern part of the Far East].
A comparative virological, immunological, and pathohistological study of 5 tick-borne encephalitis (TBE) strains differing by virulence was carried out in golden hamsters. The authors characterize the TBE virus pathogenicity sign, denoted as Pmaic genetic marker (pathogenicity for hamsters at intracerebral inoculation), which helps understand the essence of immunopathogenetic mechanisms of the TBE infectious process in man.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D001921:Brain / Q000821:virology; D006224:Cricetinae; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D005202:Asia, Eastern; D006386:Hemagglutination Tests; D008647:Mesocricetus; D013045:Species Specificity; D014774:Virulence
D000914:Antibodies, Viral
Patogeneticheskie kriterii otsenki virulentnosti shtammov virusa kleshchevogo éntsefalita, izolirovannykh na iuge dal'nego vostoka.