Use of a phage expression system to produce Fabs from human autoanti-DNA antibodies encoded by the VH4-21 gene segment.
D000595:Amino Acid Sequence; D000974:Antibodies, Antinuclear / Q000235:genetics* / Q000276:immunology; D001435:Bacteriophages / Q000235:genetics*; D001666:Binding Sites, Antibody; D003001:Cloning, Molecular / Q000379:methods*; D015723:Gene Library; D005803:Genes, Immunoglobulin; D005822:Genetic Vectors / Q000235:genetics*; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000235:genetics / Q000302:isolation & purification*; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D008969:Molecular Sequence Data; D011994:Recombinant Proteins / Q000276:immunology / Q000302:isolation & purification; D016415:Sequence Alignment
D000974:Antibodies, Antinuclear; D007140:Immunoglobulin Fab Fragments; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D011994:Recombinant Proteins