title: Molecular pharmacological aspects of histamine receptors.
abstract: In this article, we review the recent developments in the field of histamine research. Besides the description of pharmacological tools for the H1, H2 and H3 receptor, specific attention is paid to both the molecular aspects of the receptor proteins, including the recent cloning of the receptor genes, and their respective signal transduction mechanisms.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D005786:Gene Expression Regulation / Q000235:genetics; D017442:Histamine Agonists / Q000494:pharmacology*; D006633:Histamine Antagonists / Q000494:pharmacology*; D006801:Humans; D008024:Ligands; D008969:Molecular Sequence Data; D011968:Receptors, Histamine / Q000737:chemistry / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D011969:Receptors, Histamine H1 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011970:Receptors, Histamine H2 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D018100:Receptors, Histamine H3 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics
chemical_list: D017442:Histamine Agonists; D006633:Histamine Antagonists; D008024:Ligands; D011968:Receptors, Histamine; D011969:Receptors, Histamine H1; D011970:Receptors, Histamine H2; D018100:Receptors, Histamine H3