Diet-modified sex hormone metabolism: is this the way forward in recurrent respiratory papillomatosis and squamous carcinoma prophylaxis?
We report two cases of recurrent laryngeal papillomatosis in women who subsequently developed squamous cell carcinoma as they approached the climacteric. The role of human papilloma virus (HPV) and oestrogen metabolism is outlined. The use of indoles from cruciferous vegetables is also discussed.
D000328:Adult; D000818:Animals; D001984:Bronchial Neoplasms / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000601:surgery / Q000821:virology*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000378:metabolism / Q000601:surgery / Q000821:virology*; D053685:Laser Therapy; D008175:Lung Neoplasms / Q000378:metabolism; D051379:Mice; D009364:Neoplasm Recurrence, Local; D016609:Neoplasms, Second Primary; D010212:Papilloma / Q000378:metabolism / Q000601:surgery / Q000821:virology*
D004967:Estrogens