[A new method for evaluating acute toxicity intragastrically for classification of chemical substances].
The authors reviewed and presented a critical analysis of the literature on defining acute toxicity of chemicals after intragastrical administration by means of traditional methods and new ones such as fixed procedure, up-down, acute-toxic-classification. Rules and conditions for the evaluation of acute toxicity by means of these methods were presented as well as the way of defining a median, lethal dose administrated intragastrically for the purpose of chemical classification.
D000284:Administration, Oral; D000818:Animals; D015386:Hazardous Substances / Q000008:administration & dosage / Q000145:classification*; D007928:Lethal Dose 50; D018675:Toxicity Tests / Q000379:methods*
D015386:Hazardous Substances
Nowe metody oceny ostrej toksyczności droga dozoładkowa dla celów klasyfikacji substancji chemicznych.