title: [Hepatitis B virus (HBV) infection in health personnel of a hospital for adolescents. Results of a vaccine campaign].
abstract: The aim of the research is to evaluate the professional risk of the health workers of a pediatric hospital, mainly devoted to the care of adolescents. A seroepidemiological survey was therefore performed during the preliminary screening of an anti-hepatitis-B vaccination program, implemented in a suburban 150-beds pediatric hospital, with a predominance of elective surgery patients. The prevalence of past or ongoing HBV infection in a sample of adolescent inpatient (10-19 years old) in the same institution was known from an another study (13.2%). The prevalence of any HBV marker among 360 workers was 16.3%, lower in males (13.5 versus 17.7% in females), and in those with an higher level of instruction; the prevalence resulted significantly higher with increasing age and length of hospital service. Out of 321 candidates to anti-HBV vaccination 245 employees accepted the procedure (76.3%), significantly more females than males (80% versus 68.9%) and more subjects less than 30 years-old (84.3% versus 62% of subjects more than 40 years-old subjects). Only 13 subjects (5.3%) did not reach a protective titer after the third dose of the plasma-derived vaccine a protective titer. No major adverse event occurred.
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D002648:Child; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology*; D010564:Personnel, Hospital; D015995:Prevalence
chemical_list: D015415:Biomarkers; D017325:Hepatitis B Vaccines
vernacular_title: Infezione da virus-epatite B (HBV) nel personale di assistenza di un ospedale per adolescenti. Risultati di una campagna vaccinale.