Silver-stained nucleolar (Ag-NOR) cluster size in feline mammary carcinomas: lack of correlation with histological appearance, mitotic activity, tumour stage, and degree of nuclear atypia.
The relationship between Ag-NOR cluster size, mitotic index, tumour stage, degree of nuclear atypia and histological appearance was evaluated in a series of feline mammary carcinomas. The mean Ag-NOR cluster area per cell in these tumours ranged from 1.86 to 6.25 microns 2 and was not related to any other parameter studied. This suggests that Ag-NOR cluster size measurement is of poor diagnostic and prognostic value for feline mammary carcinomas.
D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D014408:Biomarkers, Tumor / Q000737:chemistry*; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000378:metabolism / Q000473:pathology*; D002415:Cats; D002467:Cell Nucleus / Q000473:pathology*; D015674:Mammary Neoplasms, Animal / Q000737:chemistry / Q000473:pathology*; D008940:Mitotic Index; D009367:Neoplasm Staging; D009697:Nucleolus Organizer Region / Q000737:chemistry / Q000473:pathology*; D016622:Silver Staining
D014408:Biomarkers, Tumor