[The automated "SynChrom" system for solid-phase synthesis of peptides and liquid column chromatography. II. Use in the solid-phase synthesis of peptides and liquid column chromatography].
Automatic solid phase peptide synthesis using the SynChrom system is described. Problems of swellographic monitoring are discussed. Combined monitoring (swellographic, spectrophotometric, and manometric) of all steps of the synthetic cycle are suggested. Potential applications of the system to liquid column chromatography were demonstrated.
D000595:Amino Acid Sequence; D001331:Automation; D002853:Chromatography, Liquid / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D013057:Spectrum Analysis
D010455:Peptides
Avtomatizirovannyĭ kompleks dlia tverdofaznogo sinteza peptidov i zhidkostnoĭ kolonochnoĭ khromatografii "SinKhrom". II. Ispol'zovanie v tverdofaznom sinteze peptidov i zhidkostnoĭ kolonochnoĭ khromatografii.