[Uveitis: late complication of undiagnosed Whipple disease].
We report a case of severe chronic bilateral uveitis in a 60-year-old white man without neurological manifestations. Spondylarthritis and isolated malabsorption suggested the diagnosis of Whipple's disease. A normal duodenal biopsy delated the diagnosis, who was secondarily demonstrated an adenopathy biopsy and macrophage study on vitrectomy sample (macrophage distended by periodic acid-Schiff positive material). With 1 year follow-up the uveitis was rapidly and completely cured by an antibiotic association (rifampicin and trimethoprim-sulfamethoxazol). The characteristics of ocular involvement in Whipple's disease and treatment of the disease are discussed.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D008875:Middle Aged; D014605:Uveitis / Q000188:drug therapy / Q000209:etiology*; D008061:Whipple Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D000900:Anti-Bacterial Agents
Uvéite: complication tardive d'une maladie de Whipple méconnue.