title: [A case report of prosthetic valve replacement for malfunction of the Hancock valve in mitral position associated with recurrent peptic ulcer and renal dysfunction].
abstract: A 62-year-old woman was admitted with malfunction of the Hancock valve in mitral position. She had been suffering from gastroduodenal ulcer for about ten years. She couldn't take warfarin after 5 years later of the initial operation due to recurrent gastrointestinal bleeding. Judging from her age and renal dysfunction, we preferred mechanical valve to avoid the risks for the reoperation. After confirming the healed ulcer with administering omeprazole, we performed prosthetic valve replacement with SJM 29 M successfully. Postoperative course was uneventful and recurrence of the ulcer was not observed.
mesh_terms: D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D009853:Omeprazole / Q000008:administration & dosage; D010437:Peptic Ulcer / Q000150:complications*; D010438:Peptic Ulcer Hemorrhage / Q000517:prevention & control; D011475:Prosthesis Failure; D012008:Recurrence; D012086:Reoperation; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D014859:Warfarin; D009853:Omeprazole