Acetaminophen pharmacokinetics after overdose.
Concentrations of acetaminophen in serum and urinary excretion rates of acetaminophen glucuronide and acetaminophen sulfate were determined in a 15-year-old female who had ingested an overdose which resulted in the absorption of an estimated 9.92 g of acetaminophen. The results obtained are in reasonably good agreement with predictions of acetaminophen disposition based upon a previously developed pharmacokinetic model of capacity-limited acetaminophen elimination, but additional studies are needed to refine that model.
D000082:Acetaminophen / Q000378:metabolism* / Q000506:poisoning / Q000652:urine; D000293:Adolescent; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008657:Metabolic Clearance Rate; D013405:Suicide
D000082:Acetaminophen