title: Transfusion medicine monitoring practices. A study of the College of American Pathologists/Centers for Disease Control and Prevention Outcomes Working Group.
abstract: OBJECTIVE
  To survey transfusion medicine practices in 1990, to determine the distribution of defects in the transfusion process, to examine the relationship between defects and complications, and to recommend improvements in the transfusion process.
  
  
  METHODS
  A mail survey that divided the transfusion process into 24 risk-prone steps and gathered defect rates on each step, along with incidence data for eight known complications of transfusions and other demographic information.
  
  
  METHODS
  Hospitals, independent laboratories, and blood centers that provide transfusion medicine services.
  
  
  METHODS
  Respondents were 1365 participants in the College of American Pathologists 1991 Blood Bank Quality Assurance Survey.
  
  
  RESULTS
  While processing 6.2 million units of blood and blood products, respondents reported detecting over 88,000 defects: 41% in the preanalytic phase of testing, 55% in the postanalytic phase, and only 4% in the analytic phase, the phase to which most monitoring efforts were devoted. A median of eight steps were actively monitored by survey participants overall, whereas 96 facilities sought defects in all 24 steps.
  
  
  CONCLUSIONS
  Analysis of the data showed several monitoring steps provide similar information. Although monitoring of the transfusion process could not be linked with prevention of the complications studied, active surveillance does focus attention on defect-prone steps and allows testing of strategies to improve the transfusion process. We describe how defect detection systems may be improved.
mesh_terms: D001771:Blood Banks / Q000592:standards* / Q000706:statistics & numerical data; D001803:Blood Transfusion / Q000592:standards* / Q000706:statistics & numerical data; D006801:Humans; D008485:Medical Audit; D008508:Medication Errors / Q000706:statistics & numerical data; D011785:Quality Assurance, Health Care; D011795:Surveys and Questionnaires; D017749:Total Quality Management / Q000379:methods; D065227:Transfusion Reaction