title: [Influenza in the 1994/95 season; composition of vaccine for the 1995/96 season].
abstract: The 1994/'95 season in the Netherlands was marked by a limited influenza activity which only emerged in late February. The influenza activity remained elevated until the end of April, which is unusually late, and epidemic activity was only reported in the south of the country. Both influenza A/H3N2 and B viruses were isolated in this period. In addition, influenza A/HINI viruses were isolated for the first time since March 1993, from two patients. The majority of the influenza A strains that circulated in the Netherlands in 1994/'95 reacted well with ferret antiserum raised against the strains of the 1994/'95 influenza vaccine, which therefore probably offered good protection. The reactivity of the B strains to antiserum raised against the vaccine strain, B/Panama/45/90, was only moderate, which implies that the protection against the Dutch influenza B strains was not optimal. Based on the results of the worldwide influenza surveillance, the World Health Organization (WHO) has recommended an alteration in both the A/H3N2 and the B component for the vaccine of 1995/1996.
mesh_terms: D004196:Disease Outbreaks; D006801:Humans; D009980:Influenza A virus / Q000302:isolation & purification*; D009981:Influenza B virus / Q000302:isolation & purification*; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000453:epidemiology / Q000821:virology*; D009426:Netherlands / Q000453:epidemiology
chemical_list: D007252:Influenza Vaccines
vernacular_title: Influenza in het seizoen 1994/'95; vaccinsamenstelling voor het seizoen 1995/'96.