[Role of hypothalamic monoaminergic structures in regulating sympatho-adrenal system function].
The effect of pharmacological destruction of hypothalamic monoaminergic terminals on the basal and cold stress-induced secretion of neurohormones of the sympathoadrenal system (SAS) in rats was studied. The data obtained on biochemical and histochemical analysis of the hypothalamus (dopamine, noradrenaline and serotonin level, the picture of catecholaminergic terminal fluorescence) were compared with adrenaline and noradrenaline content in blood. It is assumed that function of the SAS is inhibited by hypothalamic noradrenaline and stimulated by dopamine and serotonin under cold stress.
D015115:5,6-Dihydroxytryptamine / Q000494:pharmacology; D000313:Adrenal Medulla / Q000502:physiology*; D000818:Animals; D001679:Biogenic Amines / Q000502:physiology*; D003080:Cold Temperature; D003891:Desipramine / Q000494:pharmacology; D004298:Dopamine / Q000032:analysis; D006892:Hydroxydopamines / Q000494:pharmacology; D007031:Hypothalamus / Q000032:analysis / Q000502:physiology*; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D051381:Rats; D013564:Sympathetic Nervous System / Q000502:physiology*
D001679:Biogenic Amines; D006892:Hydroxydopamines; D003891:Desipramine; D004298:Dopamine; D015115:5,6-Dihydroxytryptamine; D009638:Norepinephrine
Rol' monoaminergicheskikh struktur gipotalamusa v reguliatsii funktsii simpatiko-adrenalovoĭ sistemy.