title: [Cicatrization effect of Jatropha curcas latex (Angiospermae: Euforbiaceae)].
abstract: The wound healing effects of Jathopha curcas latex upon surgical wound produced in Balb/c mice skin, were studied with a modification of the Hoowes-Sooy-Harvey method. The effects of topical treatment using single 50 ul doses of latex at different dilutions (10% to 100%) was compared with a multiple dose treatment (four 25 ul/dose q12h, latex 5% to 100%). The single dose treatment with 10%, 50% or 100% latex and the multiple dose treatment with dilutions between 5% and 10%, have a healing effect but only on males. The multiple dose treatment with 50% or pure undiluted latex produced caustic lesions to treated skin.
mesh_terms: D000287:Administration, Topical; D000818:Animals; D005260:Female; D007840:Latex / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D007840:Latex
vernacular_title: Actividad cicatrizante del látex de Jatropha curcas (Angiospermae: Euforbiaceae).