title: Unrestrained walking in cats with medial pontine reticular lesions.
abstract: The early postoperative effects of lesions, aimed to destroy the caudal pole of the nucleus reticularis pontis oralis (NRPO) and the rostral pole of the nucleus reticularis pontis caudalis (NRPC), were tested in freely moving cats, walking at moderate speed (0.4-1.0 m/s). In cats in which these structures were partly or completely destroyed, the main effect of lesions was an impairment of fore-hindlimb coordination, as shown by a change in the relationships between the lateral and diagonal time shift durations and the step cycle duration. In the second week after the surgery the values of the slopes of linear regressions relating these variables were markedly changed as compared to the preoperative data. The results suggest that the NRPO and NRPC are involved in maintaining the proper forehindlimb coordination during unrestrained locomotion in cats.
mesh_terms: D000818:Animals; D002415:Cats; D005121:Extremities / Q000502:physiology*; D016014:Linear Models; D008124:Locomotion / Q000502:physiology*; D008297:Male; D013116:Spinal Cord / Q000502:physiology*; D013997:Time Factors; D016138:Walking / Q000502:physiology*