title: [The combined intensive therapy of rheumatoid arthritis with systemic manifestations].
abstract: The efficacy of pulse therapy in combination with hemosorption or plasmapheresis, pulse therapy without extracorporeal treatment and methotrexate has been compared for 40 patients with rheumatoid arthritis (RA) with extra-articular manifestations. All kinds of intensive treatment were effective. Extracorporeal methods and pulse therapy relieved extra-articular symptoms. Isolated pulse therapy alleviated articular syndrome. The best results were obtained in double filtration of plasma in combination with pulse therapy. Such approach ensured improvement both articular and extra-articular inflammation. Combined intensive therapy proved an effective modality in RA able to produce responses in severe disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D018501:Antirheumatic Agents / Q000008:administration & dosage; D001172:Arthritis, Rheumatoid / Q000628:therapy*; D016009:Chi-Square Distribution; D003131:Combined Modality Therapy; D003422:Critical Care / Q000379:methods*; D003520:Cyclophosphamide / Q000008:administration & dosage; D005069:Evaluation Studies as Topic; D005260:Female; D006464:Hemoperfusion / Q000295:instrumentation; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D010956:Plasmapheresis / Q000295:instrumentation; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone
vernacular_title: Kombinirovannaia intensivnaia terapiia revmatoidnogo artrita s sistemnymi proiavleniiami.