title: [Natural killers and cytotoxic lymphocytes in classical hog cholera].
abstract: The formation of immune mechanisms directed at elimination of infected cells and including the activity of natural killers and cytotoxic lymphocytes was assessed in pigs infected with hog cholera virus. In acute disease natural killer activity in the blood is reduced, while in vaccinal process it is increased. Vaccination in parallel with cyclophosphamide immunodepression lead to inhibition of natural killer activity. Leukocytes and lymphocytes of immunized pigs can cause cytolysis of autologous targets infected with hog cholera virus.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D006691:Classical Swine Fever / Q000276:immunology*; D006692:Classical Swine Fever Virus / Q000276:immunology; D003520:Cyclophosphamide / Q000494:pharmacology; D007165:Immunosuppression Therapy; D007694:Killer Cells, Natural / Q000276:immunology*; D013552:Swine; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines; D003520:Cyclophosphamide
vernacular_title: Estestvennye killery i tsitotoksicheskie limfotsity pri klassicheskoĭ chume svineĭ.