title: The Wellcome Foundation Lecture, 1994. The fetal origins of adult disease.
abstract: Recent findings suggest that many human fetuses have to adapt to a limited supply of nutrients and in doing so they permanently change their physiology and metabolism. These 'programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders: stroke, diabetes and hypertension.
mesh_terms: D000368:Aged; D000818:Animals; D001724:Birth Weight; D003327:Coronary Disease / Q000209:etiology* / Q000401:mortality; D005314:Embryonic and Fetal Development; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000254:growth & development; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D010920:Placenta / Q000502:physiology