[The phagocytosis of polymorphonuclear neutrophilic granulocytes in progressive periodontitis].
The aim of this paper was the evaluation of the phagocytic activity of neutrophils in blood and in gingival pocket fluid in patients suffering from rapidly progressive periodontitis (RPP) and postjuvenile periodontitis (PJP). Prior to periodontal treatment the authors evaluated the capacity to phagocytose latex particles of peripheral blood neutrophils from 21 patients with RPP, 51 with PJP and 59 healthy subjects (control group) as well as the phagocytic activity of neutrophils in pocket fluid from 21 patients with RPP, 14 with PJP and from 20 healthy subjects. This phagocytic activity was significantly lower in all examined groups in comparison with the control group. A similar evaluation executed 3 months after treatment revealed normal phagocytosis of blood neutrophils from patients with RPP. In patients receiving complementary pharmacotherapy (spiramycine combined with metronidazol), a better improvement of phagocytosis was noted, than that observed in patients treated only surgically.
D000328:Adult; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D005888:Gingival Pocket / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D006801:Humans; D007841:Latex Fixation Tests; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D010518:Periodontitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D010587:Phagocytosis
Phagozytose der polymorphkernigen neutrophilen Granulozyten bei der progressiven Parodontitis.