[The follow-up of therapeutic remission in alcoholics].
Usage of alcohol during the period of therapeutic remission of chronic alcoholism without complete restoration of its symptoms indicates failure of therapeutic remission (FTR). A method was suggested to detect FTR by enzymic activity of gamma-glutamyltranspeptidase, aspartate transaminase, alanintransaminase and glutamate dehydrogenase. FTR is stated at differential threshold of the above enzymes 32, 25, 26 and 6.5 u/l, respectively. Validity of the method was confirmed at examination of 110 chronic alcoholics and 61 healthy persons. Early FTR detection prevents occurrence of true recurrence of chronic alcoholism.
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000175:diagnosis / Q000628:therapy*; D001219:Aspartate Aminotransferases / Q000097:blood; D004796:Clinical Enzyme Tests / Q000706:statistics & numerical data; D005500:Follow-Up Studies; D005969:Glutamate Dehydrogenase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction; D012680:Sensitivity and Specificity; D013053:Spectrophotometry; D005723:gamma-Glutamyltransferase / Q000097:blood
D005969:Glutamate Dehydrogenase; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Kontrol' terapevticheskoĭ remissii u bol'nykh alkogolizmom.