Ultrasound imaging of the masseter muscle in myotonic dystrophy patients.
Ultrasound technique was applied to measure the thickness and examine the internal structure of the masseter muscle in a group of 16 adult patients (nine women and seven men) with myotonic dystrophy (MyD) and 16 healthy individuals matched in age, sex and number of occluding teeth. The masseter thickness was measured bilaterally under both relaxed conditions and during maximal clenching. The error of measurement was found to be small, not exceeding 0.45 mm. The imaging characteristics of the masseter in most of the MyD patients was an obvious atrophy of the muscle with increased echointensity of the intramuscular tissue and loss of the internal structure concerning tendons and fasciae. The mean masseter thickness (+/- SD) in the MyD group was 10.4 (+/- 2.2) mm under relaxed conditions and 11.1 (+/- 2.4) mm during maximal clenching, compared with 13.3 (+/- 2.2) mm and 14.1 (+/- 2.4) mm, respectively, in the healthy group (P < 0.001). In conclusion, our results indicate that, in most of the myotonic dystrophy patients, the masseter muscle is atrophic with obvious signs of degeneration. Ultrasound is a useful method for both qualitative and quantitative evaluation of the condition of the masseter muscle.
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D018737:Hand Strength; D006801:Humans; D008297:Male; D008406:Masseter Muscle / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009133:Muscular Atrophy / Q000000981:diagnostic imaging; D009223:Myotonic Dystrophy / Q000000981:diagnostic imaging* / Q000473:pathology; D015588:Observer Variation; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D014463:Ultrasonography