title: [Hyperinsulinemia and severity of cardiovascular disorders in generalized lipodystrophy syndrome].
abstract: The examination of 40 patients with generalized lipodystrophy elucidated the dependence of the severity of cardiovascular disorders in these patients on the immunoreactive insulin/C-peptide index. In high values of the latter cardiovascular disorders occur more frequently. The role of insulin in pathogenesis of essential hypertension, chronic IHD is assessed.
mesh_terms: D000293:Adolescent; D000328:Adult; D002096:C-Peptide / Q000097:blood; D002318:Cardiovascular Diseases / Q000209:etiology*; D003327:Coronary Disease / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007328:Insulin / Q000097:blood*; D008060:Lipodystrophy / Q000097:blood / Q000150:complications*; D008875:Middle Aged; D012307:Risk Factors; D013577:Syndrome
chemical_list: D002096:C-Peptide; D007328:Insulin
vernacular_title: Giperinsulinemiia i vyrazhennost' serdechno-sosudistykh narusheniĭ pri sindrome generalizovannoĭ lipodistrofii.