title: Principles of selection and use of antibacterial agents.
abstract: Treatment of infection involves a complex interaction among the infecting organism (susceptibility to the therapeutic agent), host factors (immune function, site of infection, renal and hepatic metabolism), and pharmacokinetics (rate of absorption, distribution and excretion). Successful therapy requires careful consideration of these factors, and unsuccessful treatment should invoke a careful reanalysis of them.
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D016903:Drug Monitoring; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents