Fatty acid composition of palatal tissue from denture stomatitis patients.
Palatal biopsy specimens were obtained from patients with denture stomatitis. The fatty acids were extracted from the tissue, then separated, identified, and quantified by a gas-chromatographic technique. The sensitivity of this method enabled analyses of specimens with a wet weight of less than 1 mg. The concentration of the fatty acids C16:1 (n-7) and C24:1 (n-9) differed significantly between samples from hyperplastic and clinically healthy tissue in the denture stomatitis patients. By comparing specimens from denture stomatitis patients and non-denture subjects, the concentration of seven fatty acids, two saturated and five unsaturated, was found to be significantly different. A multivariate data-analytical method distinguished between the fatty acid composition in specimens from denture stomatitis patients and from non-denture subjects.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D002849:Chromatography, Gas; D003819:Denture Bases / Q000009:adverse effects*; D004952:Esters; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008297:Male; D013058:Mass Spectrometry; D008768:Methylmethacrylates / Q000009:adverse effects / Q000737:chemistry; D008875:Middle Aged; D009061:Mouth Mucosa / Q000737:chemistry*; D015999:Multivariate Analysis; D010159:Palate; D018709:Statistics, Nonparametric; D013282:Stomatitis, Denture / Q000209:etiology / Q000378:metabolism* / Q000473:pathology
D004952:Esters; D005227:Fatty Acids; D008768:Methylmethacrylates