Primary extramedullary plasmacytoma in cyclosporine-induced gingival overgrowth. A case report.
An unusual solitary extramedullary plasmacytoma developed in the gingiva of a 28 year-old male renal transplant patient with cyclosporine (CyA)-induced gingival overgrowth. On initial presentation, there was no suspicion of a tumor within the lesion. One year later, however, the lesion had increased progressively in size, and its surface was ulcerated. At this time, the lesion was excised by gingivectomy, and histopathological examination revealed plasmacytoma. CyA was discontinued and the patient has been closely observed for 4 years with no recurrence of the gingival lesion.
D000328:Adult; D016572:Cyclosporine / Q000009:adverse effects*; D005500:Follow-Up Studies; D005885:Gingival Hyperplasia / Q000139:chemically induced* / Q000473:pathology; D005887:Gingival Neoplasms / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D010954:Plasmacytoma / Q000473:pathology*; D014456:Ulcer / Q000473:pathology
D007166:Immunosuppressive Agents; D016572:Cyclosporine