title: [The histoenzymological and ultrastructural changes in the gastric mucosa in peptic ulcer after treatment with pirenzepine and histamine H2-receptor blockaders].
abstract: A study made in 72 patients showed a positive influence in ulcer disease of gastrocepine and H2-blockers of receptors to histamine on histoenzymological and ultrastructural changes in the mucous membrane of the stomach and duodenum. Gastrocepine was found to be superior to H2-blockers of receptors to histamine due to its apparent cytoprotective effect and ability to improve microcirculation.
mesh_terms: D001706:Biopsy; D005753:Gastric Mucosa / Q000187:drug effects* / Q000201:enzymology / Q000648:ultrastructure; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology; D010890:Pirenzepine / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D006635:Histamine H2 Antagonists; D010890:Pirenzepine
vernacular_title: Gistoénzimologicheskie i ul'trastruktivnye izmeneniia slizistoĭ obolochki zheludka pri iazvennoĭ bolezni posle lecheniia pirentsepinom i H2-blokatorami gistaminoretseptorov.