title: Halo nevus or halo phenomenon? A study of 142 cases.
abstract: One hundred and forty-two (142) halo nevi were reviewed. For 66 cases the diagnosis of halo nevus was made both clinically and pathologically, and for 76 cases the diagnosis was based on histological grounds alone. The nevi were classified by type and by degree of atypia. Of the 142 nevi, all were compound, junctional, or intradermal nevi except for one case of a Spitz nevus and two cases that could not be further classified. For those with a clinicopathological diagnosis of halo nevus, 11% exhibited moderate atypia; 16% exhibited minimal atypia to only focally moderate atypia; 24% minimal atypia; and 49% exhibited no significant atypia. For those cases where the diagnosis was pathological only, there was also a broad spectrum of atypia identified, with 8% exhibiting focally severe or severe atypia. This study supports the concept that the halo nevus should not be regarded as a single clinicopathological entity, but rather that the halo phenomenon occurs in a wide spectrum of nevus types exhibiting a wide spectrum of histological atypia. The pathologist is therefore encouraged to classify halo nevi on the basis of the nevus cell population alone, using whatever classification normally utilized.
mesh_terms: D000005:Abdomen / Q000473:pathology; D000293:Adolescent; D000328:Adult; D001132:Arm / Q000473:pathology; D001415:Back / Q000473:pathology; D001940:Breast / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007717:Knee / Q000473:pathology; D008297:Male; D009333:Neck / Q000473:pathology; D009508:Nevus, Pigmented / Q000145:classification / Q000175:diagnosis* / Q000473:pathology*; D012189:Retrospective Studies; D012782:Shoulder / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification / Q000473:pathology*; D013909:Thorax / Q000473:pathology