[Toxic alcohol-induced, acute intrahepatic cholestasis with reversible increase of the CA 19-9 tumor marker in chronic alcoholic hepatitis].
The case report on an acute intrahepatic cholestasis caused by alcoholic intoxication in a 52-year-old medical laboratory assistant is given. In addition to extreme pathologic cholestasis parameters the increase of the tumor marker CA 19-9 was remarkable. By means of laparoscopy and histology, chronic fatty liver hepatitis due to alcoholic intoxication was found. The tumor marker CA 19-9 returned to normal following abstinence from alcohol parallel to the deline of the cholestasis parameters, which means the diagnostic importance of tumor markers in diseases with intrahepatic cholestasis is to be seen in relative terms.
D000435:Alcoholic Intoxication / Q000473:pathology*; D001706:Biopsy; D018395:CA-19-9 Antigen / Q000097:blood*; D002780:Cholestasis, Intrahepatic / Q000473:pathology* / Q000534:rehabilitation; D005235:Fatty Liver, Alcoholic / Q000473:pathology / Q000534:rehabilitation; D005260:Female; D005500:Follow-Up Studies; D006519:Hepatitis, Alcoholic / Q000473:pathology* / Q000534:rehabilitation; D006801:Humans; D008099:Liver / Q000473:pathology; D008875:Middle Aged
D018395:CA-19-9 Antigen
Alkoholtoxische, akute intrahepatische Cholestase mit reversibler Erhöhung des Tumormarkers CA 19-9 bei chronischer Alkoholhepatitis.