title: [Influence of non-diabetic pregnancy on fructosamine and HbA1c concentration].
abstract: HbAIc and fructosamine concentrations were measured in the course of 177 nondiabetic pregnancies and compared with the corresponding values of 24 nondiabetic nonpregnant women. In all three trimesters HbAIc and fructosamine were significantly lower than the corresponding values in the nonpregnant women; HbAIc: 1st trimester 4.77 +/- 0.62%, 2nd trimester 4.38 +/- 0.59%, 3rd trimester 4.33 +/- 0.49%, p < 0.01; fructosamine 1st trimester 2.13 +/- 0.17 mmol/l, 2nd trimester 2.02 +/- 0.15 mmol/l, 3rd trimester 1.90 +/- 0.15 mmol/l, p < 0.01; nonpregnant women: HbAIc 5.13 +/- 0.41%, fructosamine 2.53 +/- 0.17 mmol/l. However, if the fructosamine is correlated to the respective total protein concentration a constant value results for the course of pregnancy. The changes in the HbAIc and fructosamine concentrations in pregnancy should be taken into account when treating pregnant diabetics.
mesh_terms: D000328:Adult; D001798:Blood Proteins / Q000378:metabolism; D015992:Body Mass Index; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood / Q000175:diagnosis; D019270:Fructosamine; D005865:Gestational Age; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008423:Maternal Age; D011247:Pregnancy; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000097:blood* / Q000175:diagnosis; D012016:Reference Values; D012709:Serum Albumin / Q000378:metabolism
chemical_list: D001798:Blood Proteins; D019270:Fructosamine; D006442:Glycated Hemoglobin; D006595:Hexosamines; D012709:Serum Albumin
vernacular_title: Der Einfluss der nichtdiabetischen Schwangerschaft auf die Fructosamin- und HbAIc-Konzentration.