title: Levels of flurithromycin in female genital tissue.
abstract: The levels of flurithromycin in gynecological tissue in 20 female patients were studied after preoperative administration. The tissue flurithromycin levels obtained were comparable to those obtained in serum at 3 and 4 h but were frequently higher than those in serum at 6 and 12 h. Flurithromycin reached the highest concentrations in ovary at 4 h and in endometrium at 6 h.
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics* / Q000494:pharmacology; D001681:Biological Assay; D004917:Erythromycin / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D016982:Micrococcus luteus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; C045925:flurithromycin; D004917:Erythromycin