title: Modification of lipogenesis in the isolated hamster flank organ through clofibric acid.
abstract: The hamster flank organ model was used to measure the effects of clofibric acid on the in vitro uptake of sodium [1-14C] acetate into lipids. Clofibric acid produces a dose-dependent inhibition of lipogenesis in the hamster flank organ in vitro.
mesh_terms: D000085:Acetates / Q000378:metabolism; D000818:Animals; D002995:Clofibric Acid / Q000494:pharmacology*; D006224:Cricetinae; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D008055:Lipids / Q000096:biosynthesis*; D008297:Male; D008647:Mesocricetus; D012627:Sebaceous Glands / Q000187:drug effects / Q000378:metabolism*
chemical_list: D000085:Acetates; D000960:Hypolipidemic Agents; D008055:Lipids; D000431:Ethanol; D002995:Clofibric Acid; D004121:Dimethyl Sulfoxide