title: [The use of high concentration ferric ammonium citrate (FAC) solution as a negative bowel contrast agent: application in MR cholangiography].
abstract: Ferric ammonium citrate (FAC) can be used as a negative contrast agent on T2- weighted images, with the use of a high concentration resulting in a significant T2 shortening effect. Ten healthy volunteers underwent MR cholangiography (MRC) using Turbo Spin Echo. High-concentration FAC was administered at a normal dosage, but was diluted in a smaller amount of water than usual. Although all precontrast images showed high intensity intestinal fluid, which aggravated visualization of the bile duct, all postcontrast images obtained 6 to 14 minutes after administration showed blackening out of the fluid, improving the overall image quality of MRC.
mesh_terms: D000328:Adult; D001652:Bile Ducts / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D005290:Ferric Compounds; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D000644:Quaternary Ammonium Compounds; D012996:Solutions
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; D000644:Quaternary Ammonium Compounds; D012996:Solutions; C013531:ferric ammonium citrate