Chronic inflammatory demyelinating polyneuropathy complicating liver transplantation.
We report on a patient who had chronic inflammatory demyelinating polyradiculoneuropathy following liver transplantation for hepatitis B-induced fulminate hepatic failure. Possible symptomatic recurrence of hepatitis B in the graft prompted a reduction in the cyclosporine dosage, which may have triggered the immune response leading to demyelination. Initial plasma exchange and then intravenous immune globulin after relapse led to marked clinical improvement.
D000328:Adult; D003711:Demyelinating Diseases / Q000209:etiology* / Q000628:therapy; D006509:Hepatitis B / Q000601:surgery; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D009460:Neurologic Examination; D010525:Peripheral Nerves / Q000503:physiopathology; D010951:Plasma Exchange; D012008:Recurrence
D016756:Immunoglobulins, Intravenous