title: Association of hypertrophic maxillary frenulum with hypoplastic left heart syndrome.
abstract: We report a previously unrecognized association between a hypertrophic frenulum separating the alveolar portion of the maxillary palatine suture with hypoplastic left heart syndrome in one fetus and seven children. A hypertrophic frenulum was not found in 25 pediatric cardiology patients without hypoplastic left heart syndrome. This finding may provide a marker for suspecting hypoplastic left heart syndrome in the neonate.
mesh_terms: D001344:Autopsy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D018636:Hypoplastic Left Heart Syndrome / Q000473:pathology*; D007223:Infant; D007621:Karyotyping; D007742:Labial Frenum / Q000473:pathology*; D008297:Male; D008437:Maxilla