[A comparative study of the frequency of stable and unstable chromosome aberrations in the gamma irradiation of human lymphocytes in vitro].
Comparative studies of the yield of stable and unstable chromosome aberrations have been carried out in human lymphocytes gamma irradiated in vitro within the doze range 0.1--1.0 Gy. It was observed that the yield of unstable chromosome aberrations (dicentrics and centric rings) is satisfactorily described for discovered dose range with linear-quadratic approximation. For stable chromosome aberrations in G-banded chromosome the dose response dependence was less expressed. The studies revealed non-random involvement of different chromosomes in translocations, and the most frequently involved are 1 and 13 chromosomes.
D000328:Adult; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics*; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1 / Q000528:radiation effects; D002882:Chromosomes, Human, Pair 13 / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000528:radiation effects* / Q000648:ultrastructure; D008297:Male
Sravnitel'noe issledovanie chastoty stabil'nykh i nestabil'nykh abberatsiĭ khromosom pri gamma-obluchenii limfotsitov krovi cheloveka in vitro.