Molecular genetics: cardiac disease and risk-related genes.
Molecular genetics is playing an increasing role in the diagnosis, treatment, and prevention of cardiac disease. Moreover, most of the genes that may cause cardiac disease or predispose an individual to cardiac disease are anticipated to be identified within the next 10 years. Several genes with risk for heart disease have been identified, such as the ACE genotype DD. Replacement gene therapy as well as use of promoter-specific drugs to act on genetic regulatory elements will encompass the future treatment of cardiovascular disease. This article provides a summary of the potential roles of genetic screening for cardiac risk factors and genetic interventions in cardiovascular disease.
D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D002874:Chromosome Mapping; D006331:Heart Diseases / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D006333:Heart Failure / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D006801:Humans; D008967:Molecular Biology; D012306:Risk