title: Methods of early detection of prostate cancer: the role of prostatic specific antigen, transrectal ultrasound and digital rectal examination.
abstract: PSA has significantly influenced the management of prostate cancer. Early detection of clinically significant cancer has been increased by combining PSA and digital rectal examination. PSA has been used as a prognostic factor for patients with local disease and as a monitoring test for patients undergoing curative therapy for localized prostate cancer.
authors.affiliation: Department of Urology, Wayne State University School of Medicine, Detroit, Michigan 48201.
authors.forename: J E
authors.initials: JE
authors.lastname: Pontes
mesh_terms: D000375:Aging / Q000276:immunology / Q000473:pathology; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D010808:Physical Examination; D017430:Prostate-Specific Antigen / Q000032:analysis*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000276:immunology; D012007:Rectum; D013997:Time Factors; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen