title: [The clinical manifestations of herpetic stomatitis in children with acute lymphoblastic leukemia].
abstract: Clinical (n = 137) and virological (n = 50) analysis of the course of herpetic stomatitis in children with acute lymphoblastic leukemia was carried out. 97.8 +/- 1.4% of cases were relapses of a chronic herpetic infection, 73.8 +/- 3.7% of cases ran a medium severe or severe course. Herpetic stomatitis in children suffering from acute lymphoblastic leukemia was characterized by the following features: 1) a high risk of infection generalization; 2) progressive necrosis of tissues in a state of leukopenia; 3) infiltration at the site of necrosis; 4) tissue anemia; and 5) risk of hemorrhage from necrotic sites.
authors.forename: E M
authors.initials: EM
authors.lastname: Mel'nichenko
authors.forename: T V
authors.initials: TV
authors.lastname: Popruzhenko
authors.forename: O V
authors.initials: OV
authors.lastname: Aleĭnikova
authors.forename: A G
authors.initials: AG
authors.lastname: Kolomiets
mesh_terms: D002648:Child; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D013283:Stomatitis, Herpetic / Q000175:diagnosis* / Q000209:etiology