title: [Pulmonary mucormycosis in leukemic patients. Apropos of 2 cases].
abstract: Mucormycosis is a rare fungal infection that has been described mainly in oncologic and diabetic patients. We here report the cases of two leukaemic patients in whom pulmonary mucormycosis was diagnosed. Prompt diagnosis, therapy with amphotericin B and surgery when possible, are the cornerstones in the treatment of this fungal infection. Although infrequent, this infection must be suspected in oncohaematological patients with lung infiltrates.
authors.affiliation: Servicio de Hematología, Hospital Ramón y Cajal, Madrid.
authors.forename: J L
authors.initials: JL
authors.lastname: Sastre
authors.forename: J
authors.initials: J
authors.lastname: Pérez-Oteyza
authors.forename: J
authors.initials: J
authors.lastname: López
authors.forename: C
authors.initials: C
authors.lastname: Cerveró
authors.forename: A
authors.initials: A
authors.lastname: Sánchez-Sousa
authors.forename: J
authors.initials: J
authors.lastname: García-Laraña
authors.forename: J A
authors.initials: JA
authors.lastname: Cancelas
authors.forename: J
authors.initials: J
authors.lastname: Odriozola
authors.forename: J L
authors.initials: JL
authors.lastname: Navarro
mesh_terms: D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage; D017809:Fatal Outcome; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D017964:Itraconazole / Q000627:therapeutic use; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications* / Q000188:drug therapy; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D015122:Mercaptopurine / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D008942:Mitoxantrone / Q000008:administration & dosage; D009091:Mucormycosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications / Q000628:therapy; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy
chemical_list: D007155:Immunologic Factors; D003561:Cytarabine; D016179:Granulocyte Colony-Stimulating Factor; D017964:Itraconazole; D000666:Amphotericin B; D008942:Mitoxantrone; D015122:Mercaptopurine; D008727:Methotrexate