RNA selection. Aptamers achieve the desired recognition.
In vitro selection procedures can generate RNA molecules, known as aptamers, that bind pre-determined ligands with an affinity and selectivity comparable to highly evolved protein molecules.
Ellington
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Department of Chemistry, Indiana University, Bloomington 47405.
D000255:Adenosine Triphosphate / Q000378:metabolism; D001120:Arginine / Q000378:metabolism; D001483:Base Sequence; D001665:Binding Sites; D002846:Chromatography, Affinity; D006801:Humans; D066298:In Vitro Techniques; D008024:Ligands; D008969:Molecular Sequence Data; D012313:RNA / Q000235:genetics / Q000378:metabolism*; D013806:Theophylline / Q000378:metabolism; D014805:Vitamin B 12 / Q000378:metabolism
D008024:Ligands; D012313:RNA; D000255:Adenosine Triphosphate; D001120:Arginine; D013806:Theophylline; D014805:Vitamin B 12