title: Antrectomy. A safe and effective bypass for unresectable pancreatic cancer.
abstract: BACKGROUND
  Pancreatic cancer is most often diagnosed too late for curative resection. Operative therapy, therefore, involves relief of biliary obstruction and relief or prevention of gastric outlet obstruction. Previous studies show that gastrojejunostomy done either therapeutically or prophylactically often causes delayed gastric emptying.
  
  
  OBJECTIVE
  To describe the results of antrectomy with Billroth II reconstruction (A/BII) as the palliative operation for gastric outlet obstruction.
  
  
  METHODS
  Fifty patients with unresectable pancreatic cancer underwent A/BII without vagotomy from 1987 through 1993. Of these patients, 42 underwent simultaneous biliary bypass; six had undergone biliary bypass from 3 weeks to 34 months previously; and two with cancer originating in the uncinate process had no biliary bypass.
  
  
  RESULTS
  One 87-year-old patient died on day 12 of azotemia and pulmonary insufficiency. The other 49 patients were discharged tolerating an oral diet an average of 11.3 days (range, 5 to 29 days) after A/BII. The length of stay following A/BII was not related to the extent of disease or to preoperative weight loss but was increased in older patients.
  
  
  CONCLUSIONS
  The A/BII is a safe and effective bypass in patients with unresectable pancreatic cancer.
authors.affiliation: Department of Surgery, Wayne State University, Detroit, Mich.
authors.forename: C E
authors.initials: CE
authors.lastname: Lucas
authors.forename: A M
authors.initials: AM
authors.lastname: Ledgerwood
authors.forename: J M
authors.initials: JM
authors.lastname: Saxe
authors.forename: J S
authors.initials: JS
authors.lastname: Bender
authors.forename: W F
authors.initials: WF
authors.lastname: Lucas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery*; D011446:Prospective Studies; D011706:Pyloric Antrum / Q000601:surgery