title: Does performance status influence the outcome of Nd:YAG laser therapy of proximal esophageal tumors?
abstract: The value of endoscopic palliative therapy for malignant obstruction in the proximal esophagus has been questioned. To assess the importance of pre-treatment performance status on treatment outcome, we reviewed the records of patients with tumors of the proximal esophagus undergoing endoscopic laser therapy between January 1986 and December 1988. As compared with 10 patients having a good performance status, eight patients with a poor performance status had a lower frequency of obtaining complete functional relief of dysphagia (14% versus 71%), an increased rate of complications (50% versus 0%), and a shorter median survival time (24 days versus 161 days). We conclude that performance status should be considered in determining the appropriateness of laser therapy in patients with proximal esophageal cancer.
authors.affiliation: Division of Gastroenterology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905.
authors.forename: G L
authors.initials: GL
authors.lastname: Alexander
authors.forename: K K
authors.initials: KK
authors.lastname: Wang
authors.forename: D A
authors.initials: DA
authors.lastname: Ahlquist
authors.forename: T R
authors.initials: TR
authors.lastname: Viggiano
authors.forename: C J
authors.initials: CJ
authors.lastname: Gostout
authors.forename: R
authors.initials: R
authors.lastname: Balm
mesh_terms: D000368:Aged; D003680:Deglutition Disorders / Q000209:etiology; D004938:Esophageal Neoplasms / Q000150:complications / Q000401:mortality / Q000532:radiotherapy*; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D053685:Laser Therapy; D007834:Lasers / Q000009:adverse effects; D008297:Male; D010166:Palliative Care; D012189:Retrospective Studies; D015996:Survival Rate