title: Constitutional trisomy 8 and myelodysplasia: report of a case and review of the literature.
abstract: A diagnosis of myelodysplastic syndrome was made in an 18-year-old patient with Warkany syndrome due to constitutional trisomy 8 mosaicism. The possible causal role of this particular chromosome constitution with respect to myelodysplasia and embryonal childhood tumors is discussed.
authors.affiliation: Istituto di Genetica Medica, Università Cattolica del Sacro Cuore, Roma, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Zollino
authors.forename: M
authors.initials: M
authors.lastname: Genuardi
authors.forename: J
authors.initials: J
authors.lastname: Bajer
authors.forename: A
authors.initials: A
authors.lastname: Tornesello
authors.forename: S
authors.initials: S
authors.lastname: Mastrangelo
authors.forename: G
authors.initials: G
authors.lastname: Zampino
authors.forename: R
authors.initials: R
authors.lastname: Mastrangelo
authors.forename: G
authors.initials: G
authors.lastname: Neri
mesh_terms: D000293:Adolescent; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D008297:Male; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D014314:Trisomy