A nitric oxide synthase inhibitor reduces desensitisation of bradykinin-induced activation of phospholipase C in sensory neurones.
Harvey
J S
JS
Sandoz Institute for Medical Research, London, UK.
Burgess
G M
GM
D000594:Amino Acid Oxidoreductases / Q000037:antagonists & inhibitors*; D000818:Animals; D000831:Animals, Newborn; D001120:Arginine / Q000031:analogs & derivatives* / Q000494:pharmacology; D001920:Bradykinin / Q000494:pharmacology*; D003994:Bucladesine / Q000494:pharmacology; D002478:Cells, Cultured; D004789:Enzyme Activation; D005727:Ganglia, Spinal / Q000201:enzymology; D007295:Inositol Phosphates / Q000378:metabolism; D007700:Kinetics; D009475:Neurons, Afferent / Q000187:drug effects / Q000201:enzymology*; D019001:Nitric Oxide Synthase; D019335:Nitroarginine; D009599:Nitroprusside / Q000494:pharmacology*; D051381:Rats; D015290:Second Messenger Systems; D010738:Type C Phospholipases / Q000378:metabolism*; D019323:omega-N-Methylarginine
D007295:Inositol Phosphates; D009599:Nitroprusside; D019335:Nitroarginine; D019323:omega-N-Methylarginine; D003994:Bucladesine; D001120:Arginine; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D010738:Type C Phospholipases; D001920:Bradykinin