title: Human genetics. What is good about cystic fibrosis?
abstract: The remarkably high level of cystic fibrosis mutations among Caucasians may be due to a reduction in heterozygotes in the severity of the diarrhea caused by enterotoxic bacteria.
authors.affiliation: University of California, Riverside 92521-0121.
authors.forename: P M
authors.initials: PM
authors.lastname: Quinton
mesh_terms: D002712:Chlorides / Q000378:metabolism; D003550:Cystic Fibrosis / Q000235:genetics*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D003967:Diarrhea / Q000382:microbiology* / Q000401:mortality; D004768:Enterotoxins / Q000502:physiology*; D004927:Escherichia coli Infections / Q000503:physiopathology*; D020022:Genetic Predisposition to Disease; D006579:Heterozygote; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D008954:Models, Biological; D012641:Selection, Genetic; D044465:White People / Q000235:genetics*
chemical_list: C505032:CFTR protein, human; D002712:Chlorides; D004768:Enterotoxins; D008565:Membrane Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator