Extensive neodymium-YAG photoirradiation of the prostate in men with obstructive prostatism.
OBJECTIVE
To determine if high-dosage, extensive photoirradiation of the prostate could be used safely in men with large prostate glands and obstruction, coupled with acceptable clinical results.


METHODS
Treatment of 25 men consecutively with eight quadrant photoirradiation of the prostate. Treatment of the next 25 men with high-dosage energy up to 109,000 joules. Simultaneous transrectal needle biopsy of the prostate performed on all 50 men after treatment. Patients evaluated with four- to sixteen-month follow-up.


RESULTS
Success rate of 86 percent on all patients with mean American Urological Association (AUA) symptom score decreasing by nineteen points and mean peak uroflow rate increasing by 7.9 cc. Needle biopsy after high-dosage laser therapy shows no laser effect on the peripheral zone.


CONCLUSIONS
High-dosage laser energy can be used safely, and allows us to treat large prostates with excellent clinical results and minimal complications.
Shanberg
A M
AM
Division of Urology, University of California Irvine Medical Center, Long Beach.
Lee
I S
IS
Tansey
L A
LA
Sawyer
D E
DE
D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications / Q000532:radiotherapy*; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000532:radiotherapy*