title: Nuclear patterns of apoptotic and developing neurons of superior cervical ganglion of newborn rat.
abstract: Superior cervical ganglion (SCG) neurons of female rats aged 3, 5 and 7 days revealed conspicuous nuclear changes in neurons undergoing postnatal cell death. Several qualitative and quantitative data such as nuclear size and shape, the presence of atypical chromocenters and chromatin textural features discriminated well neurons candidate to degeneration and those advancing in the direction of adult maturation. At least on morphological grounds, postnatal death of SCG neurons appears to be of apoptotic type. The sequence of nuclear events observed enables the recognition of the early stages of involution which prelude neuron degeneration.
authors.affiliation: Department of Cytomorphology, University of Cagliari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Diana
authors.forename: M
authors.initials: M
authors.lastname: Setzu
authors.forename: S
authors.initials: S
authors.lastname: Sirigu
authors.forename: G
authors.initials: G
authors.lastname: Diaz
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn; D017209:Apoptosis / Q000502:physiology*; D002467:Cell Nucleus / Q000502:physiology* / Q000648:ultrastructure*; D002843:Chromatin / Q000502:physiology / Q000648:ultrastructure; D005260:Female; D006651:Histocytochemistry; D007091:Image Processing, Computer-Assisted; D008854:Microscopy, Electron; D009410:Nerve Degeneration / Q000502:physiology; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013194:Staining and Labeling; D017783:Superior Cervical Ganglion / Q000502:physiology* / Q000648:ultrastructure*
chemical_list: D002843:Chromatin