Series: 'Current issues in mutagenesis and carcinogenesis.' No. 42. Strategies and philosophies of genotoxicity testing: what is the question?
A number of statements concerning the uses and effectiveness of in vitro and in vivo genetic toxicity tests have recently been made. Certain of these statements are examined using genetic toxicity and carcinogenicity data available in the literature.
Zeiger
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Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
D000818:Animals; D002273:Carcinogens; D005189:False Positive Reactions; D006801:Humans; D008322:Mammals; D015162:Micronucleus Tests; D009152:Mutagenicity Tests / Q000592:standards*; D009153:Mutagens; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics
D002273:Carcinogens; D009153:Mutagens