[The influence of prostate-specific antigen p30 on human fertility].
The influence of prostate-specific antigen p30 on human fertility was studied with purified p30, domestic anti-p30 monoclonal and polyclonal antibodies. The results showed that the anti-p30 antibody presented in human serum had no negative effect upon human fertility and the anti-p30 antibody produced by heteroimmunization did not interfere with the process of human fertility in vitro. All these imply that it is unsuitable to recommend p30 as a contraceptive vaccine antigen.
Gou
Q
Q
Hou
Y
Y
Zhang
N
N
Wu
M
M
Wang
D
D
Yang
S
S
D003269:Contraception, Immunologic; D005260:Female; D005298:Fertility; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000494:pharmacology*; D012661:Semen / Q000276:immunology
D017430:Prostate-Specific Antigen