title: Optimization of laser prostatectomy.
abstract: A recent development in the treatment of Benign Prostatic Hyperplasia (BPH) is the use of a side firing fiber device coupled with a Nd:YAG laser. In this study, a numerical and an in-vitro model were developed to calculate and visualize the temperature distribution and the associated tissue necrosis due to irradiation of the prostate with Nd:YAG laser light. Different irradiation modalities were included: a static beam, with the irradiating fiber remaining at one place and a moving beam, with the fiber scanning over the surface at different speeds. Also blood vessels were incorporated in the model and showed to have major influence on the resulting tissue necrosis.
authors.affiliation: Department of Urology, University Hospital Utrecht, The Netherlands.
authors.forename: C F
authors.initials: CF
authors.lastname: van Swol
authors.forename: R M
authors.initials: RM
authors.lastname: Verdaasdonk
authors.forename: J
authors.initials: J
authors.lastname: Mooibroek
authors.forename: T A
authors.initials: TA
authors.lastname: Boon
mesh_terms: D003198:Computer Simulation; D006801:Humans; D053685:Laser Therapy; D008297:Male; D009010:Monte Carlo Method; D009336:Necrosis; D011467:Prostate / Q000473:pathology; D011468:Prostatectomy / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000601:surgery*