Benign prostatic hyperplasia: value of MR imaging for determining histologic type.
OBJECTIVE
To assess the value of magnetic resonance (MR) imaging for determining the histologic type of benign prostatic hyperplasia (BPH).


METHODS
Unenhanced T1- and T2-weighted images and gadolinium-enhanced T1-weighted images were obtained in the transverse plane at 1.5 T in 33 patients with BPH. Hyperphasia was classified as stromal or nonstromal. Nonstromal hyperplasia was diagnosed if (a) the nodules in the inner gland had heterogeneous high signal intensity on T2-weighted images and peripheral enhancement on gadolinium-enhanced images, (b) a surgical capsule was present, or (c) the inner gland volume to total volume ratio was greater than 0.75.


RESULTS
A correct diagnosis was made with MR imaging in 23 of 24 patients with nonstromal hyperplasia and eight of nine with stromal hyperplasia (94% accuracy). In nonstromal hyperplasia, nodular lesions were seen in 20 patients and a surgical capsule was seen in 19. Eighteen patients had a transition zone ratio greater than 0.75.


CONCLUSIONS
MR imaging appears to be useful for choosing the type of pharmacotherapy performed because accurate histologic assessment is possible.
Ishida
J
J
Department of Radiology, Shimane Medical University, Enya Izumo, Japan.
Sugimura
K
K
Okizuka
H
H
Kaji
Y
Y
Moriyama
M
M
Nagaoka
S
S
Mizutani
M
M
Ishida
T
T
D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000175:diagnosis* / Q000473:pathology