title: Case report: multiple myeloma presenting as a diastolic heart failure with no evidence of amyloidosis.
abstract: The development of severe right sided congestive heart failure led to a diagnosis of immunoglobulin G (lambda) myeloma with a predominance of light chains. Cardiac catheterization and endomyocardial biopsy showed a severe diastolic dysfunction of both right and left ventricles and extensive myocardial infiltration by intercellular fibrillar tissue, which was not amyloid. This is a rare presentation of immunoglobulin deposition disease associated with immunocytic dyscrasias.
authors.affiliation: Division of Medicine, Kaplan Hospital, Rehovot, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Schattner
authors.forename: M
authors.initials: M
authors.lastname: Epstein
authors.forename: A
authors.initials: A
authors.lastname: Berrebi
authors.forename: A
authors.initials: A
authors.lastname: Caspi
mesh_terms: D000686:Amyloidosis; D009202:Cardiomyopathies; D003971:Diastole; D006333:Heart Failure / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology / Q000473:pathology; D009206:Myocardium / Q000276:immunology / Q000473:pathology
chemical_list: D007147:Immunoglobulin Light Chains