[The expression of hepatitis C antigen in hepatitis and liver cancer tissues].
30 specimens of hepatocellular carcinoma (HCC) from laporotomy biopsy and 15 specimens of hepatitis from aspiration biopsy were subjected to hepatitis C (HCV) immunohistochemistry. Anti-HCV core monoclone antibodies and ABPAP detection method were used. The results showed that 5 specimens (17%) in the HCC group and 3 (20%) in the hepatitis group were positive, with a total positive rate of 18%. The expression pattern was scattered, located in the cytoplasm. There were positive signals in the para-carcinomatous tissues of the 5 positive cases of HCC, and there were scattered positive signals just inside the cytoplasm of the cancer cells in 3 positive HCC specimens.
Liang
Y R
YR
Department of Pathology, Shantou University Medical College.
Wu
M Y
MY
Lin
Y
Y
D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000378:metabolism*; D006528:Carcinoma, Hepatocellular / Q000276:immunology* / Q000821:virology; D005260:Female; D006526:Hepatitis C / Q000276:immunology*; D018936:Hepatitis C Antigens; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000276:immunology* / Q000821:virology; D008297:Male; D008875:Middle Aged
D000956:Antigens, Viral; D018936:Hepatitis C Antigens