title: Histopathological changes following laser ablation of a left-sided accessory pathway in a human.
abstract: Laser ablation was performed intraoperatively in a patient with coronary artery disease and Wolff-Parkinson-White syndrome. Histopathological evaluation of the laser ablation site revealed a transverse laser incision in the left atrial septum and mitral valve annulus. There was hemorrhage in the atrioventricular (AV) groove with interruption of a posterolateral AV connection. The laser lesion was confined largely to the atrial aspect of the AV annulus. We conclude that laser catheter ablation of accessory pathways is feasible in humans.
authors.affiliation: Arrhythmia & Pacemaker Service, Eastern Heart Institute, Passaic, New Jersey.
authors.forename: D
authors.initials: D
authors.lastname: Mehta
authors.forename: S
authors.initials: S
authors.lastname: Bharati
authors.forename: M
authors.initials: M
authors.lastname: Lev
authors.forename: S
authors.initials: S
authors.lastname: Saksena
mesh_terms: D001283:Atrioventricular Node / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery*; D002036:Bundle of His / Q000473:pathology; D003327:Coronary Disease / Q000601:surgery; D004562:Electrocardiography; D017809:Fatal Outcome; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D012849:Sinoatrial Node / Q000473:pathology; D013617:Tachycardia, Supraventricular / Q000503:physiopathology / Q000601:surgery; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology / Q000601:surgery