title: Transcriptional control of dacB, which encodes a major sporulation-specific penicillin-binding protein.
abstract: Sporulation-specific sigma factor E (sigma E) of Bacillus subtilis is both necessary and sufficient for transcription of the dacB gene, which encodes penicillin-binding protein 5*. Evidence in support of this conclusion was obtained by primer extension analysis of dacB transcripts and the induction of active sigma E with subsequent synthesis of PBP 5* in vegetative cells.
authors.affiliation: Department of Biological Sciences, Southern Methodist University, Dallas, Texas 75275-0376.
authors.forename: E B
authors.initials: EB
authors.lastname: Simpson
authors.forename: T W
authors.initials: TW
authors.lastname: Hancock
authors.forename: C E
authors.initials: CE
authors.lastname: Buchanan
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics* / Q000254:growth & development; D001426:Bacterial Proteins / Q000378:metabolism; D001483:Base Sequence; D002352:Carrier Proteins / Q000096:biosynthesis / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D006602:Hexosyltransferases; D008969:Molecular Sequence Data; D002267:Muramoylpentapeptide Carboxypeptidase / Q000096:biosynthesis / Q000235:genetics*; D046915:Penicillin-Binding Proteins; D010406:Penicillins / Q000378:metabolism; D010458:Peptidyl Transferases; D012329:RNA, Bacterial / Q000235:genetics; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D012808:Sigma Factor; D013171:Spores, Bacterial / Q000235:genetics* / Q000254:growth & development; D014157:Transcription Factors; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D046915:Penicillin-Binding Proteins; D010406:Penicillins; D012329:RNA, Bacterial; D011993:Recombinant Fusion Proteins; D012808:Sigma Factor; D014157:Transcription Factors; C063202:sporulation-specific sigma factors; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase