title: Method for systemic anaphylactic challenge in the rat using subplantar route.
abstract: Intravenous injection of antigen is the fastest and most effective way of eliciting anaphylactic shock in previously sensitized rats. When intravenous injection is difficult or undesirable, subplantar challenge is a preferable alternative to the intraperitoneal route.
authors.affiliation: Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962.
authors.forename: S
authors.initials: S
authors.lastname: Levine
authors.forename: A
authors.initials: A
authors.lastname: Saltzman
mesh_terms: D000536:Aluminum Hydroxide / Q000276:immunology; D000707:Anaphylaxis / Q000209:etiology*; D000818:Animals; D004195:Disease Models, Animal; D005528:Foot; D005620:Freund's Adjuvant; D007271:Injections, Intradermal; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D010047:Ovalbumin / Q000008:administration & dosage* / Q000276:immunology; D010567:Pertussis Vaccine / Q000276:immunology; D051381:Rats; D011917:Rats, Inbred Lew / Q000276:immunology*; D005719:gamma-Globulins / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D010567:Pertussis Vaccine; D005719:gamma-Globulins; D000536:Aluminum Hydroxide; D010047:Ovalbumin; D005620:Freund's Adjuvant