Evaluation of Ciba Corning ACS:180 automated immunoassay system.
We evaluated the technical performance of the Ciba Corning ACS:180 automated immunoassay system for the following analytes: thyroid-stimulating hormone, free thyroxine, luteinizing hormone, follicle-stimulating hormone, prolactin, human chorionic gonadotropin, carcino-embryonic antigen, and prostate-specific antigen. The characteristics evaluated were: precision, carryover, linearity, lower limit of detection, analytical interferences, and comparison with other methods. Satisfactory results were obtained in the within-run and between-run precision studies. Neither sample nor reagent carryover was found for any assay. The range of linearity was acceptable. For some of the assays evaluated, the lower limit of detection was better than that claimed by the manufacturer. Correlation between ACS:180 methods and compared methods was adequate. We conclude that the ACS:180 offers good reliability, practicability, and performance capabilities.
Mora-Brugués
J
J
Servei de Bioquímica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Gascón-Roche
N
N
Rodríguez-Espinosa
J
J
Cortés-Rius
M
M
González-Sastre
F
F
D001322:Autoanalysis; D002272:Carcinoembryonic Antigen / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood; D005069:Evaluation Studies as Topic; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007118:Immunoassay / Q000706:statistics & numerical data*; D007986:Luteinizing Hormone / Q000097:blood; D011388:Prolactin / Q000097:blood; D017430:Prostate-Specific Antigen / Q000097:blood; D011786:Quality Control; D012680:Sensitivity and Specificity; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D017430:Prostate-Specific Antigen; D013974:Thyroxine