Cytogenetic study of angiosarcoma of the breast.
Angiosarcoma of the breast is quite rare, and the development of cutaneous angiosarcoma after segmental mastectomy and radiation therapy is even less common. A cytogenetic analysis of a mammary angiosarcoma arising in a breast after previous irradiation and segmental mastectomy for infiltrating ductal carcinoma revealed multiple clonal rearrangements involving chromosomes X, 1, 2, 3, 4, 5, 6, 7, 8, 9, 15, 17, 20, and 22. No cytogenetically analyzed angiosarcomas of the breast have been reported before.
Gil-Benso
R
R
Department of Pathology, University of Valencia, Spain.
López-Ginés
C
C
Soriano
P
P
Almenar
S
S
Vazquez
C
C
Llombart-Bosch
A
A
D001943:Breast Neoplasms / Q000235:genetics*; D018270:Carcinoma, Ductal, Breast; D002869:Chromosome Aberrations; D005260:Female; D006394:Hemangiosarcoma / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000235:genetics*