Detection of rotavirus in cerebrospinal fluid and blood of patients with convulsions and gastroenteritis by means of the reverse transcription polymerase chain reaction.
Rotavirus RNA was detected in the blood and cerebrospinal fluid from eight Japanese children with convulsions and gastroenteritis in the acute stage by means of the reverse transcription polymerase chain reaction. This may suggest that rotavirus invades the central nervous system through blood vessels.
Nishimura
S
S
Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan.
Ushijima
H
H
Nishimura
S
S
Shiraishi
H
H
Kanazawa
C
C
Abe
T
T
Kaneko
K
K
Fukuyama
Y
Y
D002675:Child, Preschool; D005243:Feces / Q000737:chemistry / Q000382:microbiology; D005260:Female; D005759:Gastroenteritis / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology*; D006801:Humans; D007223:Infant; D008297:Male; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000032:analysis / Q000097:blood / Q000134:cerebrospinal fluid; D012194:RNA-Directed DNA Polymerase; D012401:Rotavirus / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology*; D012640:Seizures / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology*
D012367:RNA, Viral; D012194:RNA-Directed DNA Polymerase