[Results of the treatment of inoperable recurrences of larynx carcinoma after total laryngectomy].
Since 1975 to 1989 in the Department of Radiotherapy of Centre of Oncology in Krakow 49 patients with inoperable recurrences of the larynx carcinoma after total laryngectomy were treated. The palliative therapy (chemotherapy and/or palliative radiotherapy) was used in 18 patients. This study presents the group of 31 patients which were treated with radical intent. Radical radiotherapy was used in 20 patients. Combined multidrug chemotherapy and radiotherapy was used in 11 patients: in 2 patients chemotherapy VBM was used in combination with radiotherapy and 9 patients received the induction chemotherapy (treatment schedules containing Cisplatin) followed by radical radiotherapy. Observations show that the effectiveness of the induction chemotherapy combined with radiotherapy. Two year symptom-free 3 patients (15). Better results were observed after combined treatment with the use the induction chemotherapy combined with radiotherapy. Two year symptom-free survival was achieved in 4 patients (44%). These findings require confirmation in the greater group of patients.
Sas-Korczyńska
B
B
Kliniki Radioterapii Centrum Onkologii im. M. Skłodowskiej-Curie, Oddział, Krakowie.
Korzeniowski
S
S
Skołyszewski
J
J
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D007825:Laryngectomy; D015182:Lymphatic Irradiation; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D010166:Palliative Care; D016896:Treatment Outcome
D000970:Antineoplastic Agents