[The correlation between postsynaptic inhibition and GABA, opioid peptides, SP in electroacupuncture].
Identified tract cells in lumbar enlargement were recorded from intact anaesthetized rats. The prolongation of the latency of antidromic action potential was a measure of postsynaptic inhibition. Both ST 36 and SP 6 were stimulated electrically. In EA group (N = 12) EA prolonged the latency for 0.111 +/- 0.022 ms (P < 0.001). In bicuculline group (N = 12) the prolongation of the latency for 0.010 +/- 0.004 ms (P < 0.05) by EA was less than that of EA group with statistical significance. In naloxone group (N = 12) and SP antiserum group (N = 12) EA did not induce a significant prolongation of the latency. It suggested that GABA, opioides and SP might be involved in postsynaptic inhibition induced by EA.
Fang
Z
Z
Institute of Acupuncture and Moxibustion, China Academy of TCM, Beijing.
Yu
Q
Q
Li
Y
Y
D015667:Acupuncture Analgesia; D000818:Animals; D004558:Electric Stimulation; D015671:Electroacupuncture; D004723:Endorphins / Q000502:physiology; D005260:Female; D008297:Male; D051381:Rats; D013373:Substance P / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D004723:Endorphins; D013373:Substance P; D005680:gamma-Aminobutyric Acid