Epidemiological characteristics of HBV and HDV chronic liver diseases.
The authors describe the results of prospective examination of the incidence and importance of hepatitis B virus and hepatitis D virus in the aetiology of chronic liver disease at Slavonski Brod Hospital. HBV incidence is significant in the aetiology of chronic liver disease, since it has been found in 100/144 (69.4%) of the examinees. Most of the patients were male (75.0%), their mean age was 32.8, and their age ranged between 15 and 60. A high percentage (37.0%) was found in the category of HBV infection high-risk patients. Most of them were intravenous drug addicts, their mean age was 24.9, and they were mostly male (96.9%). In most patients HBV infection caused a milder histological and clinical form of chronic liver disease, i.e., chronic persistent hepatitis. The disease was recorded in 62.9% of the patients outside of the high-risk category, and it was found in 52.6% of the high-risk patients. The incidence of the hepatitis D virus in the aetiology of chronic liver disease was found in 19/100 (19.0%) of the HBV positive patients. 18/19 of the HDV infection patients belonged to the high-risk category, 16 of them being drug addicts. Hepatitis D virus infection led to serious clinical and histological forms of chronic liver disease in most cases: chronic active hepatitis and cirrhosis of the liver in 89.5% of the cases, and chronic persistent hepatitis in only 19.5% of the cases.
Jelić
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Department of Medicine, Medical Centre, Slavonski Brod.
Jelić
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O
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D003699:Hepatitis D / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged