title: Indocyanine green videoangiography of angioid streaks.
abstract: OBJECTIVE
  The fluorescein angiographic features of angioid streaks are variable, and angioid streaks and their main complication, choroidal neovascularization, can sometimes be difficult to visualize in the presence of diffuse pigment migration, diffuse atrophy of the retinal pigment epithelium, or hemorrhage. The objective of the present investigation was to define the indocyanine green angiographic features of angioid streaks and to compare them with findings on fluorescein angiography.
  
  
  METHODS
  For this prospective study, we recruited 22 consecutive patients, 21 of whom had angioid streaks and one who had typical peau d'orange appearance of the fundus. Complete ophthalmologic examination, fluorescein angiography, and indocyanine green videoangiography by the means of scanning laser ophthalmoscope were performed on all patients.
  
  
  RESULTS
  In 21 patients with angioid streaks and in one patient with peau d'orange appearance of the fundus, indocyanine green videoangiography showed angioid streaks in the form of hyperfluorescent lines with numerous associated hyperfluorescent foci. The angioid streaks were more clearly visualized and were seen to be more numerous and larger by indocyanine green videoangiography than with red-free images or fluorescein angiography. Choroidal neovascularization was suspected in six eyes but could be precisely localized by fluorescein angiography in only three eyes. Indocyanine green angiography allowed precise localization of choroidal neovascularization in all six of these eyes.
  
  
  CONCLUSIONS
  These findings indicate that indocyanine green videoangiography provides different information than fluorescein angiography in the evaluation of angioid streaks and can more precisely localize their neovascular complications.
authors.affiliation: Department of Ophthalmology, Höpital Intercommunal, Créteil, France.
authors.forename: M
authors.initials: M
authors.lastname: Quaranta
authors.forename: S Y
authors.initials: SY
authors.lastname: Cohen
authors.forename: R
authors.initials: R
authors.lastname: Krott
authors.forename: M
authors.initials: M
authors.lastname: Sterkers
authors.forename: G
authors.initials: G
authors.lastname: Soubrane
authors.forename: G J
authors.initials: GJ
authors.lastname: Coscas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000793:Angioid Streaks / Q000150:complications / Q000175:diagnosis*; D002829:Choroid / Q000098:blood supply; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000209:etiology; D011446:Prospective Studies; D014741:Video Recording
chemical_list: D007208:Indocyanine Green