title: Correlates of ventricular ectopic activity in isolated systolic hypertension. SHEP Cooperative Research Group.
abstract: Ventricular ectopic activity was recorded at baseline in 5.6% of the 12-lead electrocardiograms and 8.2% of the 2-minute rhythm strips of 4674 subjects with isolated systolic hypertension (systolic blood pressure 160 to 219 mm Hg, diastolic blood pressure < 90 mm Hg) participating in the Systolic Hypertension in the Elderly Program (SHEP). In this study 1.3% had 6 to 10 ventricular premature beats (VPB), and 0.7% had > 10 VPB on the 2-minute rhythm strip. Correlates of VPB presence on the 12-lead ECG were older-age male sex, presence of Q/QS pattern and higher heart rate. Participants with serum potassium < 3.5 mmol/L had a higher prevalence of VPB. Similarly, the number of VPB on the 2-minute rhythm strip was associated with male sex, increasing age, with lower serum potassium, history of palpitations, and presence of Q/QS patterns.
authors.affiliation: University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903-0019.
authors.forename: J B
authors.initials: JB
authors.lastname: Kostis
authors.forename: R
authors.initials: R
authors.lastname: Allen
authors.forename: D M
authors.initials: DM
authors.lastname: Berkson
authors.forename: J D
authors.initials: JD
authors.lastname: Curb
authors.forename: J
authors.initials: J
authors.lastname: Davey
authors.forename: R H
authors.initials: RH
authors.lastname: Grimm
authors.forename: W D
authors.initials: WD
authors.lastname: Hall
authors.forename: C R
authors.initials: CR
authors.lastname: Lacy
authors.forename: M
authors.initials: M
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Miller
mesh_terms: D000368:Aged; D005117:Cardiac Complexes, Premature / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013599:Systole