title: Effects of preoperative methoxamine on blood loss and haemodynamic variables during transurethral prostatic resection under spinal anaesthesia.
abstract: Thirty-six patients who presented for transurethral prostatic resection were allocated randomly to one of two groups. Patients in group A were given methoxamine 10 mg i.m., 15 min before spinal anaesthesia. Patients in group B acted as a control group. All patients received spinal anaesthesia. Preoperative administration of methoxamine 10 mg i.m. decreased blood loss significantly and improved haemodynamic stability compared with the control group.
authors.affiliation: Departments of Anaesthesia and Surgery, University College Hospital, Galway, Ireland.
authors.forename: F A
authors.initials: FA
authors.lastname: Chambers
authors.forename: D P
authors.initials: DP
authors.lastname: O'Toole
authors.forename: M O
authors.initials: MO
authors.lastname: Corcoran
authors.forename: P W
authors.initials: PW
authors.lastname: Keane
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001794:Blood Pressure / Q000187:drug effects; D002496:Central Venous Pressure / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008729:Methoxamine / Q000627:therapeutic use*; D008875:Middle Aged; D011229:Preanesthetic Medication; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000601:surgery; D013997:Time Factors
chemical_list: D008729:Methoxamine