title: [The influence of prostate-specific antigen p30 on human fertility].
abstract: The influence of prostate-specific antigen p30 on human fertility was studied with purified p30, domestic anti-p30 monoclonal and polyclonal antibodies. The results showed that the anti-p30 antibody presented in human serum had no negative effect upon human fertility and the anti-p30 antibody produced by heteroimmunization did not interfere with the process of human fertility in vitro. All these imply that it is unsuitable to recommend p30 as a contraceptive vaccine antigen.
authors.forename: Q
authors.initials: Q
authors.lastname: Gou
authors.forename: Y
authors.initials: Y
authors.lastname: Hou
authors.forename: N
authors.initials: N
authors.lastname: Zhang
authors.forename: M
authors.initials: M
authors.lastname: Wu
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Yang
mesh_terms: D003269:Contraception, Immunologic; D005260:Female; D005298:Fertility; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000494:pharmacology*; D012661:Semen / Q000276:immunology
chemical_list: D017430:Prostate-Specific Antigen