title: Rapid staining with carcinoembryonic antigen aids limited excision of extramammary Paget's disease treated by Mohs surgery.
abstract: Extensive extramammary Paget's (EMPD) disease of the perineum in a 68-year-old man was treated by Mohs surgery. To facilitate identification of involved tissue a rapid staining carcinoembryonic antigen was used. This technique proved a useful adjunct to conventional hemotoxylin-eosin (H&E) stains. It was especially useful in highlighting involvement in areas of marked dysplasia/artifact where discrimination is often difficult. It is recommended that such a technique offers considerable benefits over H&E staining when confronted by such tissue morphology.
authors.affiliation: Department of Dermatology, University of Minnesota, Minneapolis 55455.
authors.forename: D W
authors.initials: DW
authors.lastname: Harris
authors.forename: D A
authors.initials: DA
authors.lastname: Kist
authors.forename: K
authors.initials: K
authors.lastname: Bloom
authors.forename: C B
authors.initials: CB
authors.lastname: Zachary
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005834:Genital Neoplasms, Male / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D010145:Paget Disease, Extramammary / Q000473:pathology / Q000601:surgery*; D012611:Scrotum; D016038:Skin Transplantation; D013194:Staining and Labeling / Q000379:methods
chemical_list: D002272:Carcinoembryonic Antigen