Rapid staining with carcinoembryonic antigen aids limited excision of extramammary Paget's disease treated by Mohs surgery.
Extensive extramammary Paget's (EMPD) disease of the perineum in a 68-year-old man was treated by Mohs surgery. To facilitate identification of involved tissue a rapid staining carcinoembryonic antigen was used. This technique proved a useful adjunct to conventional hemotoxylin-eosin (H&E) stains. It was especially useful in highlighting involvement in areas of marked dysplasia/artifact where discrimination is often difficult. It is recommended that such a technique offers considerable benefits over H&E staining when confronted by such tissue morphology.
Harris
D W
DW
Department of Dermatology, University of Minnesota, Minneapolis 55455.
Kist
D A
DA
Bloom
K
K
Zachary
C B
CB
D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005834:Genital Neoplasms, Male / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D010145:Paget Disease, Extramammary / Q000473:pathology / Q000601:surgery*; D012611:Scrotum; D016038:Skin Transplantation; D013194:Staining and Labeling / Q000379:methods
D002272:Carcinoembryonic Antigen