Facilitation and disfacilitation of muscle responses after repetitive transcranial cortical stimulation and electrical peripheral nerve stimulation.
Compound muscle responses were recorded after repetitive electrical stimulation of the peripheral nerve and after transcranial electrical and magnetic stimulation in 5 healthy persons. The enlargement of the second response at intervals between 30 and 50 msec is more pronounced after cortical magnetic and electrical stimulation than after peripheral nerve stimulation. This difference is believed to be a result of facilitatory mechanisms involving the summation of effects from conditioning and test stimuli along the entire central motor pathway. The facilitation at 10 msec interval, which is only seen after magnetic, but not after electrical transcranial stimulation could indicate an intracortical mechanism.
Claus
D
D
Department of Neurology, University of Erlangen-Nuremberg, Germany.
Brunhölzl
C
C
D000200:Action Potentials / Q000502:physiology; D000328:Adult; D004558:Electric Stimulation; D006801:Humans; D008280:Magnetics; D009044:Motor Cortex / Q000502:physiology*; D009132:Muscles / Q000502:physiology*; D010525:Peripheral Nerves / Q000502:physiology*