[The interferon status in diabetes mellitus].
The investigation of interferon status in 54 diabetes mellitus patients gave evidence for high levels of blood serum interferon, leukocyte inhibition of alpha-interferon production against moderate synthesis of gamma interferon. More marked alterations in the interferon status were registered in severe insulin-dependent diabetes mellitus complicated by angiopathies and running more than 5 years. Compensation of metabolic processes was not relevant to interferon status. Variations in the levels of alpha- and gamma-interferons in the course ob observation occurred in 30% of the patients.
Sidorova
L D
LD
Bondar'
I A
IA
Iavorskaia
V E
VE
Evstropov
A N
AN
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000276:immunology; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000209:etiology / Q000276:immunology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000209:etiology / Q000276:immunology*; D005260:Female; D006801:Humans; D007372:Interferons / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D007372:Interferons