title: Pentacyclic triterpenes derived from Maprounea africana are potent inhibitors of HIV-1 reverse transcriptase.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612.
authors.forename: T
authors.initials: T
authors.lastname: Pengsuparp
authors.forename: L
authors.initials: L
authors.lastname: Cai
authors.forename: H H
authors.initials: HH
authors.lastname: Fong
authors.forename: A D
authors.initials: AD
authors.lastname: Kinghorn
authors.forename: J M
authors.initials: JM
authors.lastname: Pezzuto
authors.forename: M C
authors.initials: MC
authors.lastname: Wani
authors.forename: M E
authors.initials: ME
authors.lastname: Wall
mesh_terms: D001565:Benzoates / Q000302:isolation & purification* / Q000494:pharmacology; D054303:HIV Reverse Transcriptase; D015497:HIV-1 / Q000201:enzymology*; D015498:HIV-2 / Q000201:enzymology; D010946:Plants, Medicinal / Q000737:chemistry*; D012194:RNA-Directed DNA Polymerase; D018894:Reverse Transcriptase Inhibitors; D013329:Structure-Activity Relationship; D013636:Tanzania; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D001565:Benzoates; D018894:Reverse Transcriptase Inhibitors; D014315:Triterpenes; C087541:1-hydroxymaprounic 3-p-hydroxybenzoate; C087542:2-hydroxymaprounic acid 2,3-bis(4-hydroxybenzoate); C072416:reverse transcriptase, Human immunodeficiency virus 2; D054303:HIV Reverse Transcriptase; D012194:RNA-Directed DNA Polymerase