In-vitro and in-vivo immunobiological properties of murine monoclonal anti-Brucella antibodies.
Features and protective activity of anti-Brucella murine monoclonal antibodies (Mabs) versus B. melitensis 16M were studied. All Mabs tested were able to confer a good passive protection and showed correlative biological properties in immunological reactions.
Adone
R
R
Istituto Superiore di Sanità, Laboratorio di Medicina Veterinaria, Rome, Italy.
Ciuchini
F
F
Pistoia
C
C
Piccininno
G
G
D000818:Animals; D000907:Antibodies, Bacterial / Q000008:administration & dosage / Q000097:blood / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000097:blood / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology; D001709:Biotechnology; D017347:Brucella melitensis / Q000276:immunology* / Q000302:isolation & purification; D002006:Brucellosis / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D003429:Cross Reactions; D000939:Epitopes / Q000276:immunology; D007116:Immunization, Passive; D007132:Immunoglobulin Isotypes / Q000276:immunology; D066298:In Vitro Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000382:microbiology
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000939:Epitopes; D007132:Immunoglobulin Isotypes