The genotoxicity of Hinosan, an organophosphorus pesticide in the in vivo mouse.
The genotoxic potential of Edifenphos (Hinosan) was studied in the in vivo mouse system. The test parameters used were chromosomal aberration assay, micronucleus test and sperm abnormality assay. The dose and time yield effects of the pesticide were investigated for chromosomal aberrations and the micronucleus test. Statistically significant chromosomal aberrations, micronucleus and sperm abnormalities revealed the genotoxicity of this compound.
Jayashree
I V
IV
Department of Studies in Biosciences, Mangalore University, India.
Vijayalaxmi
K K
KK
Abdul Rahiman
M
M
D000818:Animals; D002800:Cholinesterase Inhibitors / Q000633:toxicity*; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D051379:Mice; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects*; D009946:Organothiophosphorus Compounds / Q000633:toxicity*; D013094:Spermatozoa / Q000187:drug effects*
D002800:Cholinesterase Inhibitors; D007306:Insecticides; D009946:Organothiophosphorus Compounds; C002108:edifenphos