Postmenopausal virilization due to ovarian hyperthecosis.
A case of a 66-year-old obese woman with type II diabetes mellitus and a 4 year history of virilism is presented. After removal of the ovaries the raised testosterone levels returned to normal and signs of virilism gradually receded. The histological finding of nodular hyperthecosis of the ovaries is discussed in relation to hyperinsulinaemia.
Agorastos
T
T
B'University Clinic of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Hippokrateion Hospital, Greece.
Argyriadis
N
N
Fraggidis
G
G
Vakiani
A
A
Zournatzi
V
V
Bontis
J
J
D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D010053:Ovary / Q000473:pathology; D017698:Postmenopause / Q000502:physiology; D012016:Reference Values; D013739:Testosterone / Q000097:blood; D013799:Theca Cells / Q000473:pathology; D013798:Thecoma / Q000473:pathology* / Q000601:surgery; D014770:Virilism / Q000473:pathology* / Q000601:surgery
D013739:Testosterone