Differential distribution of heterogeneous nuclear ribonucleoproteins in rat tissues.
Heterogeneous nuclear ribonucleoproteins bind to RNA as long as it is transcribed. Since their binding can be sequence-specific, it has been suggested that their expression in different tissues could vary depending on the specific mRNA processing requirements. In order to better establish this possibility we studied the presence of the heterogeneous nuclear ribonucleoproteins A1, A2/B1, C and D in the cell nuclei of different rat tissues by one- and two-dimensional immunoblotting. We found that these proteins were heterogeneously distributed among tissues and that they were found in different proportions.
Faura
M
M
Centre d'Investigació, Hospital La Fe, València, Spain.
Renau-Piqueras
J
J
Bachs
O
O
Bosser
R
R
D017398:Alternative Splicing; D000818:Animals; D015153:Blotting, Western; D002467:Cell Nucleus / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D006367:HeLa Cells; D000076245:Heterogeneous Nuclear Ribonucleoprotein A1; D034481:Heterogeneous-Nuclear Ribonucleoprotein Group A-B; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D006801:Humans; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012261:Ribonucleoproteins / Q000378:metabolism*; D013045:Species Specificity; D014018:Tissue Distribution
D000076245:Heterogeneous Nuclear Ribonucleoprotein A1; D034481:Heterogeneous-Nuclear Ribonucleoprotein Group A-B; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012261:Ribonucleoproteins; C439768:hnRNP A2