title: Of mice and mutants: target size and sensitivity.
authors.affiliation: Merck Research Laboratories, West Point, PA 19486-0004, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Skopek
mesh_terms: D000477:Alkylating Agents / Q000633:toxicity; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics; D029968:Escherichia coli Proteins; D005038:Ethylnitrosourea / Q000633:toxicity; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D056968:Lac Repressors; D051379:Mice; D008822:Mice, Transgenic; D016296:Mutagenesis; D009152:Mutagenicity Tests / Q000379:methods*; D012097:Repressor Proteins / Q000235:genetics; D012680:Sensitivity and Specificity; D019076:Transgenes / Q000187:drug effects* / Q000235:genetics
chemical_list: D000477:Alkylating Agents; D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D056968:Lac Repressors; D012097:Repressor Proteins; D007041:Hypoxanthine Phosphoribosyltransferase; D005038:Ethylnitrosourea