title: Profiles of chicken macrophage effector functions.
abstract: In contrast to the mammalian system, avian species lack the so-called "resident" or "harvestable" macrophage population in the abdominal exudate. However, macrophages can be recruited into the chicken's abdominal cavity (presumably from the blood monocyte pool) if an inflammatory agent such as Sephadex is injected. The kinetics of inflammatory cell recruitment in terms of time, cell type, and state of activation to perform a particular effector function is currently an active area of research. This report will provide information on several chicken macrophage effector functions, including in vivo chemotaxis, phagocytosis, bacterial uptake and killing, biosynthesis of nitric oxide and various enzymes, and monokines such as interleukin-1 and granulocyte colony-stimulating factor.
authors.affiliation: Department of Poultry Science, North Carolina State University, Raleigh 27695-7608.
authors.forename: M A
authors.initials: MA
authors.lastname: Qureshi
authors.forename: J A
authors.initials: JA
authors.lastname: Marsh
authors.forename: R R
authors.initials: RR
authors.lastname: Dietert
authors.forename: Y J
authors.initials: YJ
authors.lastname: Sung
authors.forename: C
authors.initials: C
authors.lastname: Nicolas-Bolnet
authors.forename: J N
authors.initials: JN
authors.lastname: Petitte
mesh_terms: D000135:Acid Phosphatase / Q000096:biosynthesis; D000818:Animals; D002460:Cell Line; D002645:Chickens / Q000276:immunology*; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism; D007375:Interleukin-1 / Q000096:biosynthesis; D008264:Macrophages / Q000276:immunology* / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009573:Nitrites / Q000378:metabolism
chemical_list: D007375:Interleukin-1; D009573:Nitrites; D016179:Granulocyte Colony-Stimulating Factor; D000135:Acid Phosphatase