title: Carcinoma of the prostate: race as a prognostic indicator in definitive radiation therapy.
abstract: OBJECTIVE
  To characterize the racial differences in prognostic factors and treatment outcome for patients undergoing radiation therapy for carcinoma of the prostate.
  
  
  METHODS
  From January 1975 through December 1989, 489 white and 157 black men with carcinoma of the prostate underwent irradiation. Factors analyzed were patient age, tumor stage and grade, prostate-specific antigen (PSA) levels, and disease-control and survival rates.
  
  
  RESULTS
  More black patients than white patients were found to have poorly differentiated tumors. Black patients had higher PSA levels before and after treatment, resulting in a higher distant failure rate and poorer overall, cause-specific, and disease-free survival rates.
  
  
  CONCLUSIONS
  Black men have more aggressive prostatic tumors, a higher rate of metastasis, and a poorer survival rate than do white men.
authors.affiliation: Department of Radiation Oncology, Eastern Virginia Medical School, Norfolk 23507.
authors.forename: J A
authors.initials: JA
authors.lastname: Kim
authors.forename: D A
authors.initials: DA
authors.lastname: Kuban
authors.forename: A M
authors.initials: AM
authors.lastname: el-Mahdi
authors.forename: P F
authors.initials: PF
authors.lastname: Schellhammer
mesh_terms: D000368:Aged; D044383:Black People; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D015996:Survival Rate; D044465:White People
chemical_list: D017430:Prostate-Specific Antigen