title: A G-protein beta subunit that is expressed in the central nervous system of the mollusc Lymnaea stagnalis identified through cDNA cloning.
abstract: We have cloned cDNA encoding a G-protein beta subunit from the central nervous system (CNS) of the mollusc Lymnaea stagnalis. The deduced protein is very homologous to other metazoan beta subunits. Thus, the Lymnaea CNS can be used as a model system to study beta gamma subunits in their native setting since its large neurons can be manipulated and studied relatively easily in vivo.
authors.affiliation: Graduate School of Neurosciences Amsterdam, Research Institute Neurosciences Vrije Universiteit, Faculty of Chemistry, Department of Biochemistry and Molecular Biology, The Netherlands.
authors.forename: J C
authors.initials: JC
authors.lastname: Knol
authors.forename: E
authors.initials: E
authors.lastname: Roovers
authors.forename: E R
authors.initials: ER
authors.lastname: van Kesteren
authors.forename: R J
authors.initials: RJ
authors.lastname: Planta
authors.forename: E
authors.initials: E
authors.lastname: Vreugdenhil
authors.forename: H
authors.initials: H
authors.lastname: van Heerikhuizen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002490:Central Nervous System / Q000737:chemistry*; D018076:DNA, Complementary / Q000138:chemical synthesis; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D008195:Lymnaea / Q000235:genetics* / Q000648:ultrastructure; D008969:Molecular Sequence Data; D012313:RNA / Q000302:isolation & purification; D016415:Sequence Alignment
chemical_list: D018076:DNA, Complementary; D012313:RNA; D019204:GTP-Binding Proteins