[Interferon treatment of type C fulminant hepatitis].
On the contrary to Western countries, there are a substantial number of patients with type C fulminant hepatitis (FH) including coinfection on type A and type B hepatitis in Asian countries. The pathogenesis of FH is not fully understood, however, recent clinical observations suggest that enhanced host immune responses contribute to hepatocyte destruction in type C FH. In contrast to type B FH, type C FH is characterized by gradual and continuous liver necrosis probably duo to persistent infection of hepatitis C virus. Administration of interferon with immunosuppressive agents is the treatment of choice. Prognosis may be improved if the treatment is started in the early stage of the disease.
Yoshiba
M
M
Division of Gastroenterology, Showa University Fujigaoka Hospital.
Inoue
K
K
Sekiyama
K
K
D000328:Adult; D016572:Cyclosporine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006501:Hepatic Encephalopathy / Q000628:therapy*; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D007372:Interferons / Q000008:administration & dosage*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage
D016572:Cyclosporine; D007372:Interferons; D008775:Methylprednisolone