Transverse nail ridgings (Beau's lines) induced by chemotherapy.
Transverse grooves of the nails, designated as Beau's lines, were observed in a patient with malignant lymphoma given chemotherapy. Beau's lines disappeared in the treatment-free intervals. This observation supports the concept that these lines are the result of the suppressed growth of the nail matrix caused by antimitotic drugs.
Ben-Dayan
D
D
Department of Medicine B, Hasharon Hospital, Golda Medical Center, Petah-Tiqva, Israel.
Mittelman
M
M
Floru
S
S
Djaldetti
M
M
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects; D002945:Cisplatin / Q000009:adverse effects; D003520:Cyclophosphamide / Q000009:adverse effects; D003907:Dexamethasone / Q000009:adverse effects; D004317:Doxorubicin / Q000009:adverse effects; D005047:Etoposide / Q000009:adverse effects; D006258:Head and Neck Neoplasms / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000188:drug therapy; D008297:Male; D009260:Nail Diseases / Q000139:chemically induced* / Q000473:pathology; D009262:Nails / Q000187:drug effects / Q000473:pathology; D011241:Prednisone / Q000009:adverse effects; D014750:Vincristine / Q000009:adverse effects
D001761:Bleomycin; D014750:Vincristine; D005047:Etoposide; D003907:Dexamethasone; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D007069:Ifosfamide; D011241:Prednisone