title: Can the risk for Down syndrome be reliably modified by second-trimester ultrasonography?
authors.forename: G E
authors.initials: GE
authors.lastname: Palomaki
authors.forename: J E
authors.initials: JE
authors.lastname: Haddow
mesh_terms: D004314:Down Syndrome / Q000000981:diagnostic imaging* / Q000196:embryology / Q000453:epidemiology; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012107:Research Design; D012307:Risk Factors; D016216:Ultrasonography, Prenatal