Human micronucleus counts are correlated with age, smoking, and cesium-137 dose in the Goiânia (Brazil) radiological accident.
A random sample of 276 people representing control, direct exposure, and probable indirect exposure in the Goiânia, Brazil radiological accident was examined using micronuclei as indicators of cytogenetic damage. The Goiânia subjects were analyzed for interactions of age, lifestyle, and ionizing radiation dose. Increases in micronucleus frequencies were most strongly correlated with the dose of ionizing radiation, but age, alcohol consumption, and smoking habits also affected micronucleus frequencies. Despite these additional influences, micronucleus frequencies can be useful as biological dosimeters.
da Cruz
A D
AD
Department of Biology, Catholic University of Goiás, Goiânia, Brazil.
McArthur
A G
AG
Silva
C C
CC
Curado
M P
MP
Glickman
B W
BW
D000059:Accidents; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking; D001773:Blood Cells / Q000528:radiation effects*; D001938:Brazil; D002588:Cesium Radioisotopes / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D015162:Micronucleus Tests; D008875:Middle Aged; D011829:Radiation Dosage; D012907:Smoking
D002588:Cesium Radioisotopes