Identification of AMPA receptors in catfish electroreceptor organs.
Single afferent unit recording in microampullae of the catfish revealed that bath-applied AMPA increases both resting discharge frequency and electrically evoked responses. The potency of AMPA is of the order of 10 microM. DNQX strongly inhibits the excitatory effects of AMPA. The results suggest the presence of AMPA receptors at the synaptic membrane of ampullary electroreceptor organs in the catfish.
Andrianov
G N
GN
Pavlov Institute of Physiology, Russian Academy of Sciences, St Petersburg.
Peters
R C
RC
Bretschneider
F
F
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D004558:Electric Stimulation; D007059:Ictaluridae / Q000378:metabolism*; D008465:Mechanoreceptors / Q000187:drug effects / Q000502:physiology*; D009412:Nerve Fibers / Q000187:drug effects / Q000502:physiology; D009475:Neurons, Afferent / Q000187:drug effects / Q000502:physiology; D011810:Quinoxalines / Q000494:pharmacology; D018091:Receptors, AMPA / Q000187:drug effects / Q000378:metabolism*; D017470:Receptors, Glutamate / Q000187:drug effects / Q000502:physiology; D013569:Synapses / Q000502:physiology; D013570:Synaptic Membranes / Q000187:drug effects / Q000502:physiology; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid / Q000494:pharmacology
D011810:Quinoxalines; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; C056723:FG 9041; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid