title: Enantioselective degradation of alpha-hexachlorocyclohexane and cyclodiene insecticides in roe-deer liver samples from different regions of Germany.
abstract: Remarkably high concentrations of alpha-hexachlorocyclohexane (alpha-HCH), cis-heptachlorepoxide and oxychlordane were found in roe-deer liver samples both from the northern and southern German states Schleswig-Holstein and Baden-Württemberg, respectively. The data revealed no significant regional differences, but they showed some common characteristics: a preferential degradation of (+)-alpha-HCH, and a preferential enrichment of (+)-oxychlordane and of (+)-cis-heptachlorepoxide as determined by chiral capillary gas chromatography using modified cyclodextrin phases. Calculation of the spearman rank correlation coefficients rS supported the assumption that higher concentrations of alpha-HCH may result in a stronger decomposition of the (+)-enantiomer, while higher levels of cis-heptachlorepoxide and oxychlordane appear to lead to a faster decomposition of the respective (-)-enantiomer or a preferential formation of the respective (+)-enantiomer.
authors.affiliation: Institut für Organische Chemie, University of Hamburg, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Pfaffenberger
authors.forename: I
authors.initials: I
authors.lastname: Hardt
authors.forename: H
authors.initials: H
authors.lastname: Hühnerfuss
authors.forename: W A
authors.initials: WA
authors.lastname: König
authors.forename: G
authors.initials: G
authors.lastname: Rimkus
authors.forename: A
authors.initials: A
authors.lastname: Glausch
authors.forename: V
authors.initials: V
authors.lastname: Schurig
authors.forename: J
authors.initials: J
authors.lastname: Hahn
mesh_terms: D000818:Animals; D001673:Biodegradation, Environmental; D002706:Chlordan / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D003670:Deer; D005858:Germany; D006534:Heptachlor Epoxide / Q000032:analysis* / Q000378:metabolism; D001556:Hexachlorocyclohexane / Q000032:analysis* / Q000378:metabolism; D008099:Liver / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism
chemical_list: D006534:Heptachlor Epoxide; D002706:Chlordan; C008743:oxychlordane; D001556:Hexachlorocyclohexane