[Immunophenotyping in chronic B-cell lymphatic leukemia].
The authors present the results of immunophenotyping analysis of cells from 67 patients with the diagnosis of B-CLL from group of 393 adults examined by immunophenotyping because of a haematological malignity. Characteristic for B-CLL is the finding of surface molecules HLA DR, B lymphocytic superficial molecules and CD5. Aberrant membrane equipment of B-CLL cells is suggested by the rare absence of some pan B lymphocytic sign. Marked reduction of T lymphocyte ratios, their sub-populations and NK cells is associated with immunodeficiency manifestations which are common in patients with B-CLL.
Kopecký
O
O
Oddĕlení klinické imunologie a alergologie FN, Hradec Králové.
Krejsek
J
J
Voglová
J
J
Derner
V
V
D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D018956:CD5 Antigens; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology*; D016131:Lymphocyte Subsets; D008297:Male; D008875:Middle Aged
D015703:Antigens, CD; D018956:CD5 Antigens; D006684:HLA-DR Antigens