Large volume leukapheresis to maximize peripheral blood stem cell collection.
Large volume leukapheresis, defined as the processing of greater than three volumes of blood at one sitting, can be safely and easily performed using a variety of cell separators in a range of patients. This paper describes the history, technique, outcome, complications, and proposed uses for this procedure.
Hillyer
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Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322.
D000818:Animals; D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34; D001804:Blood Transfusion, Autologous; D006410:Hematopoiesis / Q000187:drug effects; D016298:Hematopoietic Cell Growth Factors / Q000494:pharmacology; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000737:chemistry / Q000187:drug effects; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation / Q000379:methods*
D015703:Antigens, CD; D018952:Antigens, CD34; D016298:Hematopoietic Cell Growth Factors