title: Genotoxicity evaluation of Rastim 30 DKV, the plant growth regulator, on five test systems.
abstract: The possible mutagenic activity of Rastim 30 DKV, a new plant growth regulator, was studied on five model test systems. It did not increase the frequency of His+ revertants in Salmonella typhimurium strains TA97, TA98, TA100, TA1535, TA1538 in the absence and the presence of S9 mix. It slightly increased rates of genetic changes in Saccharomyces cerevisiae, mainly convertants at the tryptophan locus. No clastogenic effect was observed after Vicia faba root-tip meristem treatment, and at the lowest concentration used its mitotic activity was significantly increased. No chlorophyll mutants after the treatment of two cultivars of barley were observed. Though no sex-linked recessive lethals were scored in Drosophila melanogaster males, the rates of aneuploids induced in their germ cells were significantly increased.
authors.affiliation: Department of Genetics, Comenius University, Faculty of Science, Bratislava, Slovak Republic.
authors.forename: E
authors.initials: E
authors.lastname: Miadoková
authors.forename: S
authors.initials: S
authors.lastname: Podstavková
authors.forename: V
authors.initials: V
authors.lastname: Vlcková
authors.forename: V
authors.initials: V
authors.lastname: Dúhová
authors.forename: B
authors.initials: B
authors.lastname: Böhmová
authors.forename: M
authors.initials: M
authors.lastname: Trebatická
authors.forename: J
authors.initials: J
authors.lastname: Grolmus
authors.forename: J
authors.initials: J
authors.lastname: Húska
authors.forename: D
authors.initials: D
authors.lastname: Vlcek
mesh_terms: D000818:Animals; D052160:Benzothiazoles; D004331:Drosophila melanogaster / Q000235:genetics; D007887:Fabaceae / Q000235:genetics; D005260:Female; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D010937:Plant Growth Regulators / Q000633:toxicity*; D010946:Plants, Medicinal; D012441:Saccharomyces cerevisiae / Q000235:genetics; D012486:Salmonella typhimurium / Q000235:genetics; D013844:Thiazoles / Q000633:toxicity*
chemical_list: D052160:Benzothiazoles; D009153:Mutagens; D010937:Plant Growth Regulators; D013844:Thiazoles; C085663:Rastim 30 DKV