[Concentrations of acute phase proteins in serum during the first two hours of hemodialysis using cuprophane and cellulose acetate dialyzers in patients with chronic renal failure].
In ten patients with chronic renal failure (CRF) serum concentrations of alpha 1-acid glycoprotein, alpha 1-antitrypsin, prealbumin, hemopexin, transferrin, haptoglobin, C3c and C4 complement components, ceruloplasmin, alpha 2-macroglobulin were determined using Partigen plates before, 30 min. and 2 hours after beginning of HD. Serum concentrations of C3c complement component, prealbumin increased significantly during HD using CU dialyser, but changes during HD using CA dialyser were not significant. Serum concentrations of alpha 1-antitrypsin, hemopexin increased significantly after two hours of HD using CA dialyser, but changes during HD using CU dialyser were again not significant. Serum concentrations of alpha 1-acid glycoprotein, transferrin, haptoglobin, ceruloplasmin, C4 complement component during HD using both dialyzers did not change significantly. Serum concentration of alpha 2-macroglobulin was higher after two hours of HD. The type of dialysis membrane has important influence on changes of serum acute phase proteins during the initial period of HD.
Starzyk
J
J
Oddziału Nefrologii Wojewódzkiego Szpitala Zespolonego, Kielcach.
Bartelik
S
S
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000328:Adult; D002482:Cellulose / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D006435:Renal Dialysis; D013997:Time Factors
D000209:Acute-Phase Proteins; D008567:Membranes, Artificial; C005062:acetylcellulose; D002482:Cellulose; C009865:cuprammonium cellulose