title: The care and fitting of Naka-Rushton functions to electroretinographic intensity-response data.
abstract: We developed an automated system to estimate parameters of the Naka-Rushton function based on a heuristic model of the electroretinogram intensity-response series. Data from a population of patients with central retinal vein occlusion were used to examine the ability of the derived parameters to predict the development of neovascularization of the iris. The predictive performance of this automated system in central retinal vein occlusion is comparable to that of a human expert.
authors.affiliation: Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD.
authors.forename: M L
authors.initials: ML
authors.lastname: Severns
authors.forename: M A
authors.initials: MA
authors.lastname: Johnson
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D003936:Diagnosis, Computer-Assisted; D004596:Electroretinography; D006801:Humans; D007498:Iris / Q000098:blood supply; D008875:Middle Aged; D008954:Models, Biological; D009389:Neovascularization, Pathologic / Q000175:diagnosis* / Q000209:etiology; D011237:Predictive Value of Tests; D012170:Retinal Vein Occlusion / Q000150:complications / Q000503:physiopathology*