Further complexities of the Rh antigen D disclosed by testing category DII cells with monoclonal anti-D.
The reaction pattern of monoclonal anti-D with category DII cells differed from those of other category D cells. DII cells express epD1, epD2, epD3, epD5, epD6/7 and epD8 but lack epD4 and a new epitope epD9. The new epitope, epD9, is proposed to explain the failure of some monoclonal anti-D (previously considered to be anti-epD3) to react with DII cells.
Lomas
C
C
Medical Research Council Blood Group Unit, London, U.K.
McColl
K
K
Tippett
P
P
D000911:Antibodies, Monoclonal; D000939:Epitopes; D005260:Female; D006801:Humans; D010455:Peptides / Q000097:blood*; D012204:Rh-Hr Blood-Group System / Q000097:blood*
D000911:Antibodies, Monoclonal; D000939:Epitopes; D010455:Peptides; D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen