title: Spinal and brain-stem SEPs and H reflex during enflurane anesthesia.
abstract: Whereas cortical SEPs are altered by halogenated anesthetics, spinal and subcortical SEPs are thought to be hardly affected. In this study the spinal N13 potential (recorded with anterior neck reference) showed a significant delay with enflurane anesthesia. The P13 and P14 far-field potentials, however, remained unchanged. Our results indicate that oligosynaptic as well as polysynaptic pathways are influenced by halogenated anesthetics and that enflurane has different effects on spinal gray matter and cuneate synapses. Our data also demonstrate that earlobe reference recordings are not adequate to measure pharmacologic effects on subcortical SEPs.
authors.affiliation: Laboratoire de Neurophysiologie Clinique, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: Mavroudakis
authors.forename: A
authors.initials: A
authors.lastname: Vandesteene
authors.forename: E
authors.initials: E
authors.lastname: Brunko
authors.forename: M
authors.initials: M
authors.lastname: Defevrimont
authors.forename: D
authors.initials: D
authors.lastname: Zegers de Beyl
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D001933:Brain Stem / Q000502:physiology*; D004569:Electroencephalography; D004737:Enflurane; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006181:H-Reflex / Q000502:physiology*; D006801:Humans; D008297:Male; D011930:Reaction Time / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*
chemical_list: D004737:Enflurane