title: Neurodevelopment in pediatric HIV infection. The use of CAT/CLAMS. Clinical Adaptive Test/Clinical Linguistic and Auditory Milestone Scale.
abstract: Pediatric neuro-AIDS may be the first clinical manifestation of HIV infection in children born to HIV-infected mothers. As part of the neurodevelopmental examination of children, the Clinical Adaptive Test/Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS) was investigated as a tool for pediatricians to use to monitor the development of children at risk for HIV infection. The CAT/CLAMS was found to detect neurodevelopmental differences between HIV-infected and uninfected children at 12 and 18 months of age. Good correlations were found between the CAT/CLAMS and concurrently administered Bayley Scales of Infant Development. These findings suggest that the CAT/CLAMS should be considered as a part of the neurodevelopmental examination of children at risk for pediatric neuro-AIDS.
authors.affiliation: Department of Pediatrics, University of Maryland School of Medicine, Baltimore.
authors.forename: R C
authors.initials: RC
authors.lastname: Wachtel
authors.forename: V J
authors.initials: VJ
authors.lastname: Tepper
authors.forename: D
authors.initials: D
authors.lastname: Houck
authors.forename: C J
authors.initials: CJ
authors.lastname: McGrath
authors.forename: C
authors.initials: C
authors.lastname: Thompson
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000635:transmission; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D009483:Neuropsychological Tests; D012306:Risk