title: Failure of sheep-goat hybrid conceptuses to develop to term in sheep-goat chimaeras.
abstract: Six hybrid pregnancies were established: three in sheep-goat chimaeras, one in a sheep-(sheep-goat)hybrid chimaera and two in does. Pregnancies were monitored weekly by ultrasonography and peripheral concentrations of pregnancy specific protein B (PSPB) were measured. Placental development as detected by ultrasonography appeared to be slower in hybrid-in-goat pregnancies than in hybrid-in-chimaera pregnancies, although this difference was not reflected in PSPB concentrations. Time of fetal death could not be predicted from PSPB concentrations. Chimaeras appeared to carry hybrid pregnancies longer than ewes and does usually carry hybrid pregnancies, but none was carried to term.
authors.affiliation: Department of Animal Science, University of California, Davis 95616-8521.
authors.forename: R A
authors.initials: RA
authors.lastname: Gustafson
authors.forename: G B
authors.initials: GB
authors.lastname: Anderson
authors.forename: R H
authors.initials: RH
authors.lastname: BonDurant
authors.forename: G R
authors.initials: GR
authors.lastname: Sasser
mesh_terms: D000818:Animals; D002678:Chimera / Q000502:physiology*; D004624:Embryo Transfer / Q000662:veterinary; D005260:Female; D005313:Fetal Death; D006041:Goats / Q000097:blood / Q000235:genetics*; D006824:Hybridization, Genetic; D010920:Placenta / Q000000981:diagnostic imaging; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000235:genetics*; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis; D012756:Sheep / Q000097:blood / Q000235:genetics*; D016216:Ultrasonography, Prenatal / Q000662:veterinary; D014599:Uterus / Q000000981:diagnostic imaging
chemical_list: D011268:Pregnancy-Specific beta 1-Glycoproteins