[Serum HCV-RNA for evaluation of interferon-readministration to the former non responders in chronic hepatitis C].
We investigated the efficacy of retreatment with interferon in patients with chronic hepatitis C who were non responders to the initial interferon treatment. The results were as follows: 1) The effective rate was very low and 2 of the 16 responded to the 2nd treatment. 2) Serum HCV-RNA levels before retreatment with interferon were compared among the 4 responders and the 13 non responders to interferon and it was significantly lower in the 4 responders. 3) HCV-genotypes may be useful to predict the efficacy of interferon readministration.
Sata
M
M
Second Department of Medicine, Kurume University School of Medicine.
Tanikawa
K
K
D000328:Adult; D002908:Chronic Disease; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D007372:Interferons / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood*; D016896:Treatment Outcome
D012367:RNA, Viral; D007372:Interferons