Cytogenetic adaptive response induced by pre-exposure in human lymphocytes and marrow cells of mice.
The frequencies of chromosomal aberrations both in human lymphocytes and in mouse marrow cells exposed to low-level radiation were higher than in their unexposed controls. However, the frequencies of chromosomal aberrations in two kinds of cells pre-exposed to low-level radiation induced by a subsequent high dose of X-rays or gamma-rays were lower than those of the groups only exposed to high-level radiation. This implies that adaptive responses for cytogenetic indicators might be induced by pre-exposure to low-level radiation. The results also show the existence of possible variations between individual lymphocytes.
Zhang
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China Institute for Radiation Protection, Taiyuan, People's Republic of China.
D000222:Adaptation, Physiological; D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects*; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D008297:Male; D051379:Mice; D011836:Radiation Tolerance; D014965:X-Rays