Recent advances in hepatic transplantation at the University of Pittsburgh.
FK506 undoubtedly improved the survival advantage of hepatic allotransplantation. Hepatic-intestinal and multivisceral transplantation has also become a feasible therapy for patients with combined intestinal and liver failure. With better understanding of the immunologic and metabolic aspects of allo- and xenotransplantation, further clinical attempts to transplant animal organs to humans may be considered with the hope for a better outcome in the very near future.
Abu-Elmagd
K
K
University of Pittsburgh Medical Center, Pittsburgh Transplant Institute, Pennsylvania.
Bronsther
O
O
Jain
A
A
Irish
W
W
Ramos
H
H
Marino
I R
IR
Dodson
F
F
Selby
R
R
Doyle
H
H
Furukawa
H
H
D000046:Academic Medical Centers; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D006085:Graft Survival; D006801:Humans; D007422:Intestines / Q000637:transplantation; D008107:Liver Diseases / Q000401:mortality / Q000601:surgery; D016031:Liver Transplantation / Q000276:immunology / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010215:Papio; D010414:Pennsylvania; D016032:Randomized Controlled Trials as Topic; D015996:Survival Rate; D016559:Tacrolimus / Q000627:therapeutic use; D014183:Transplantation, Heterologous
D016559:Tacrolimus