[Signal-transducing ATP -- mediator of transmembranous transmission of mitogenic signals to cellular growth].
The paper summarizes the experimental data obtained by the author and his collective body on studies into the author's discovered cellular phenomenon--rapid living cellular plasma membranous generation and utilization of short-lived signal-transducing ATP as a transmembranous mitogenic signal-to-cellular growth transmitter by growth factor receptors associated with tyrosine kinase. It considers the conditions of the generation, cellular localization, possible mechanism of signal ATP on the plasma membrane of a living cell. It also emphasizes that there is a correlation between the generation of a short-lived signal-transducing ATP from ADP and inorganic phosphate and the oxidation of NAD.H with oxygen conjugated with proton-activated, sodium-translocating phosphorylation.
Karelin
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D000255:Adenosine Triphosphate / Q000502:physiology*; D000818:Animals; D002450:Cell Communication; D002455:Cell Division / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D002468:Cell Physiological Phenomena; D002478:Cells, Cultured; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D011975:Receptors, Mitogen / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
D006133:Growth Substances; D011975:Receptors, Mitogen; D000255:Adenosine Triphosphate