Ki67 and AgNORs staining in squamous cell carcinoma of the cervix: a comparison.
Ki67 immunostaining was performed on 48 cases of squamous cell carcinoma of the cervix and AgNOR silver staining on 29 cases. There was no correlation between the clinical stage of the tumor and the two methods of staining but both methods correlated with histological grade. There was no correlation between the two methods of staining in 17 case where they were done on adjacent blocks of tumor tissue. High Ki67 score but not high AgNOR count was significantly associated with early recurrence.
Chung
T K
TK
Department of Obstetrics and Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT.
Cheung
T H
TH
Wong
F W
FW
Wong
Y F
YF
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen; D009363:Neoplasm Proteins; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009687:Nuclear Proteins; D009697:Nucleolus Organizer Region; D016622:Silver Staining; D013194:Staining and Labeling / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*
D019394:Ki-67 Antigen; D009363:Neoplasm Proteins; D009687:Nuclear Proteins