[The extravascular contractile system of the human placenta: a new aspect for function of the organ?].
In the chorionic plate and stem villi of the human placenta besides the fetal blood vessel system a second extravascular contractile system (EVCS) exists. The cells of this system contain contractile and intermediate filaments and are dipeptidyl peptidase-IV- and NO-synthase-type-I-(NOS)-immunoreactive. Therefore it can be assumed that these cells cleave the vasodilator Substance P (by DPP IV) and produce NO (by NOS) and may contribute to a modulation of the EVCS.
Graf
R
R
Institut für Anatomie, Freie Universität Berlin.
Schönfelder
G
G
Langer
J U
JU
Oney
T
T
Reutter
W
W
Schmidt
H
H
D000594:Amino Acid Oxidoreductases / Q000502:physiology; D003285:Contractile Proteins / Q000502:physiology* / Q000648:ultrastructure; D046508:Culture Techniques; D018819:Dipeptidyl Peptidase 4; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Q000502:physiology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007382:Intermediate Filaments / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D019001:Nitric Oxide Synthase; D010920:Placenta / Q000033:anatomy & histology / Q000502:physiology*; D011247:Pregnancy; D013373:Substance P / Q000378:metabolism
D003285:Contractile Proteins; D013373:Substance P; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D018819:Dipeptidyl Peptidase 4