title: Enormous hemangiosarcoma of the heart.
abstract: This report describes a 26-year-old patient with hemangiosarcoma of the heart and summarizes the clinicopathological features in previous reports of patients with cardiac angiosarcoma. The patient was admitted to our hospital because of a syncope and one episode of nocturnal dyspnea and hemoptysis. In his history he complained of progressive weakness and loss of weight over the past 2 months. Echocardiography and computed tomography of the chest showed inhomogeneous masses in the pericardial cavity completely surrounding the heart and involving the ascending aorta and the superior vena cava. Histological examination of the tissue obtained from the mass by fine needle technique revealed a poorly differentiated malignant tumor of mesenchymal origin. Exploratory thoracotomy followed by tumor biopsies showed an inoperable cardiac hemangiosarcoma of enormous size with multiple metastases in both lungs. Palliative tumor resection was not performed. During the postoperative course the patient still required controlled ventilation. After 3 days of cytostatic chemotherapy no regression of tumor mass was seen by chest radiography. Cardiorespiratory insufficiency was progressive, and the patient died within 3 weeks after admission.
authors.affiliation: I. Medizinische Klinik, Johannes-Gutenberg-Universität Mainz, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Herr
authors.forename: A
authors.initials: A
authors.lastname: Schwarting
authors.forename: B
authors.initials: B
authors.lastname: Wittig
authors.forename: R
authors.initials: R
authors.lastname: Wanitschke
authors.forename: G
authors.initials: G
authors.lastname: Schnitzler
authors.forename: J
authors.initials: J
authors.lastname: Weinerth
authors.forename: W
authors.initials: W
authors.lastname: Jochum
authors.forename: U
authors.initials: U
authors.lastname: Hake
authors.forename: K H
authors.initials: KH
authors.lastname: Meyer zum Büschenfelde
mesh_terms: D000328:Adult; D004452:Echocardiography; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000150:complications / Q000473:pathology*; D006394:Hemangiosarcoma / Q000150:complications / Q000473:pathology* / Q000556:secondary; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D010166:Palliative Care; D012770:Shock, Cardiogenic / Q000209:etiology; D013575:Syncope / Q000209:etiology