title: [Cytokine production by MTSC 4 cells, an established mouse thymic dendritic cell line].
abstract: The cytokine production by MTSC 4 cells, a murine thymic dendritic cell line established in our laboratory, has been investigated. Without exogenous stimulation, the MTSC 4 cells constitutively produce multiple types of cytokines, including IL-1, IL-6, IL-7, CSF, IFN and Chemotactic factor (CF). Of which, IL-6 and IFN were abundant: IL-1 and Chemokine, moderate: IL-7 and CSF at low level. MTSC4 cells could not produce detectable either IL-3 of TNF alpha. The establishment of MTSC 4 may be useful in the analysis of the mechanism of thymus selection, and in the study of the network regulation of autocrined cytokines.
authors.affiliation: Beijing Medical University.
authors.forename: Z G
authors.initials: ZG
authors.lastname: Liu
authors.forename: W F
authors.initials: WF
authors.lastname: Chen
authors.forename: L X
authors.initials: LX
authors.lastname: Cao
authors.forename: X W
authors.initials: XW
authors.lastname: Pang
authors.forename: P X
authors.initials: PX
authors.lastname: Zhang
authors.forename: Q
authors.initials: Q
authors.lastname: Yu
mesh_terms: D000818:Animals; D002460:Cell Line; D016207:Cytokines / Q000378:metabolism*; D003713:Dendritic Cells / Q000166:cytology / Q000378:metabolism*; D007372:Interferons / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D013950:Thymus Gland / Q000166:cytology*
chemical_list: D016207:Cytokines; D015850:Interleukin-6; D007372:Interferons