ATP receptors.
ATP receptors continue to be found in an ever wider range of tissues in the brain and the periphery. Much of the recent research on these receptors focuses on features that would distinguish ATP-mediated excitatory synaptic transmission from that mediated through glutamate or acetylcholine receptors. These features include kinetics of the synaptic currents, voltage-independent calcium permeability of the underlying channels, interactions with adenosine, and various direct modulators of the ATP-gated ion channel.
Edwards
F A
FA
Department of Pharmacology, University of Sydney, New South Wales, Australia.
D000241:Adenosine / Q000502:physiology; D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D002118:Calcium / Q000378:metabolism; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D010539:Permeability; D018048:Receptors, Purinergic P2 / Q000378:metabolism*; D013569:Synapses / Q000502:physiology
D007473:Ion Channels; D018048:Receptors, Purinergic P2; D000255:Adenosine Triphosphate; D000241:Adenosine; D002118:Calcium