Evaluation of potential mutagenic effect of the liquid smoke preparation UTP in vivo: cytogenetic analysis of mouse bone marrow.
The effect of the liquid smoke preparation (UTP) on chromosomes of mouse bone marrow cells was evaluated by cytogenetic analysis. UTP was administered to male and female mice in four concentrations: 100, 10, 1 and 0.1 ml UTP/1000 ml of drinking water continuously during 4 weeks ad libitum. The UTP concentrations used did not show any mutagenic effect under these testing conditions.
Kazimírová
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Institute of Preventive and Clinical Medicine, Department of Genetics, Bratislava, Slovak Republic.
Jablonická
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D000818:Animals; D001835:Body Weight / Q000187:drug effects; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D005260:Female; D005421:Flavoring Agents / Q000633:toxicity*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D010636:Phenols / Q000633:toxicity*; D012906:Smoke
D005421:Flavoring Agents; D009153:Mutagens; D010636:Phenols; D012906:Smoke; C085747:UTP 1