title: Intraduct carcinoma of the breast (duct carcinoma in situ).
abstract: A retrospective study of non-invasive ductal carcinoma in situ in a series of women is presented. The epidemiology, clinical characteristics and results in 65 patients treated by mastectomy or breast-conserving surgery, with or without radiation therapy, are reported. The significant recurrence rate and high proportion of invasive cancers among patients with recurrences are noted. Recurrences were more frequent in patients with larger tumours and those with comedo-type intraduct carcinomas. Implications and guidelines for therapy are presented.
authors.affiliation: Department of Surgery, University of the Witwatersrand, Johannesburg.
authors.forename: M
authors.initials: M
authors.lastname: Lange
authors.forename: I
authors.initials: I
authors.lastname: Kessel
authors.forename: E
authors.initials: E
authors.lastname: Kessler
authors.forename: R H
authors.initials: RH
authors.lastname: Lakier
authors.forename: N R
authors.initials: NR
authors.lastname: Lange
authors.forename: S
authors.initials: S
authors.lastname: Ross-Thompson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000601:surgery*; D002278:Carcinoma in Situ / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000601:surgery*; D005260:Female; D006801:Humans; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies