Hormone treatments in the common 'hormone-dependent' carcinomas.
Current understanding of the mechanisms of action of hormonal therapies in carcinomas of the breast, prostate, endometrium and ovary is briefly reviewed. The range of available hormonal therapies for each disease is considered together with response rates, toxicity and any evidence for survival benefit. Practical guidelines for the palliative use of hormonal therapies are suggested.
Wood
B C
BC
Department of Radiotherapy, Royal South Hants Hospital, Southampton, UK.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000188:drug therapy; D005260:Female; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000188:drug therapy; D010166:Palliative Care; D011471:Prostatic Neoplasms / Q000188:drug therapy
D006728:Hormones