title: [Examination in clinical course of HCV in interferon treatment].
abstract: We treated 812 patients who had chronic hepatitis C with interferon (IFN) and studied the effects of interferon. We defined complete response as normalization of amino-transferase more than 6 months after termination of IFN. Complete response by means of IFN therapy is dependent to some factors, that is HCV-genotype, quantity of HCV-RNA, histology. Cases of HCV genotype III or IV, CH2A, less than 10(5) copy/ml of HCV-RNA are effective in treatment of IFN. On the other hand, cases of HCV genotype II, CH2B, more than 10(6) copy/ml of HCV-RNA are effective in treatment of IFN.
authors.affiliation: Department of Gastroentelology in Toranomon Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Kumada
mesh_terms: D005838:Genotype; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D007372:Interferons / Q000008:administration & dosage*; D011379:Prognosis; D012367:RNA, Viral / Q000097:blood
chemical_list: D012367:RNA, Viral; D007372:Interferons