title: Wound repair in the context of extracellular matrix.
abstract: Wound repair requires a continually evolving network of interactions among cells, cytokines and the extracellular matrix. Cell-surface integrins provide a mechanical connection between matrix components and the cytoskeleton, and integrins can transduce an astonishing variety of signals along pathways that may intercept the pathways triggered by cytokine receptors.
authors.affiliation: Department of Dermatology, State University of New York at Stony Brook 11794-8165.
authors.forename: J
authors.initials: J
authors.lastname: Gailit
authors.forename: R A
authors.initials: RA
authors.lastname: Clark
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000502:physiology; D016923:Cell Death / Q000502:physiology; D016207:Cytokines / Q000502:physiology; D003599:Cytoskeleton / Q000502:physiology; D010450:Endopeptidases / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology*; D006801:Humans; D018960:Hyaluronan Receptors; D016023:Integrins / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D016201:Receptors, Lymphocyte Homing / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
chemical_list: D002352:Carrier Proteins; D016207:Cytokines; D018960:Hyaluronan Receptors; D016023:Integrins; D011956:Receptors, Cell Surface; D016201:Receptors, Lymphocyte Homing; D010450:Endopeptidases