Biodevelopmental aspects of conduct disorder in boys.
The association between biochemical parameters and conduct disorder (CD) was studied in 22 boys admitted to a residential center. Three-methoxy-4-hydroxyphenylglycol (MHPG) levels were significantly higher in prepubertal CD youth than in pubertal/post pubertal CD youth. Homovanillic acid (HVA) levels were significantly lower in CD youth under age 12.0 years than in non CD youth under age 12.0 years. The implications of these biodevelopmental findings in the study of CD are discussed.
Gabel
S
S
Department of Psychiatry and Behavioral Sciences, Children's Hospital, Denver, Colorado 80218-1088.
Stadler
J
J
Bjorn
J
J
Shindledecker
R
R
Bowden
C L
CL
D000367:Age Factors; D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis / Q000201:enzymology* / Q000523:psychology; D004299:Dopamine beta-Hydroxylase / Q000097:blood / Q000378:metabolism; D006719:Homovanillic Acid / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000097:blood / Q000134:cerebrospinal fluid; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D008995:Monoamine Oxidase / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D011569:Psychiatric Status Rating Scales; D012701:Serotonin / Q000097:blood / Q000134:cerebrospinal fluid
D012701:Serotonin; D008734:Methoxyhydroxyphenylglycol; D006897:Hydroxyindoleacetic Acid; D004299:Dopamine beta-Hydroxylase; D008995:Monoamine Oxidase; D006719:Homovanillic Acid