Immunological mechanism of chronic liver injury in viral hepatitis.
Chronic hepatitis B and chronic hepatitis C centering on immunohistochemical studies of the liver were investigated as possible mechanisms of the chronicity of viral hepatitis. Although liver cell injury was presumed to be caused by CTL in both chronic hepatitis B and C, other mechanisms of cell injury were also presumed with chronic hepatitis, type C, including autoimmune mechanisms.
Yamada
G
G
First Department of Internal Medicine, Okayama University Medical School.
Tsuji
T
T
D000956:Antigens, Viral / Q000378:metabolism; D015815:Cell Adhesion Molecules / Q000378:metabolism; D006680:HLA Antigens / Q000378:metabolism; D006509:Hepatitis B / Q000276:immunology* / Q000473:pathology; D006511:Hepatitis B Antigens / Q000378:metabolism; D006526:Hepatitis C / Q000276:immunology* / Q000473:pathology; D018936:Hepatitis C Antigens; D006521:Hepatitis, Chronic / Q000276:immunology* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000276:immunology / Q000473:pathology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
D000956:Antigens, Viral; D015815:Cell Adhesion Molecules; D006680:HLA Antigens; D006511:Hepatitis B Antigens; D018936:Hepatitis C Antigens