title: Dust mite allergens in the office environment.
abstract: The objective of this study was to evaluate the extent of dust mite infestation and its contribution to the health complaints in office settings. The methodology recommended for residential dwellings was evaluated for use in the work environment. Der p I allergen-specific ELISA was chosen as a primary method. A liquid chromatography method for guanine is suggested as a backup method to cover a few cases where other mite species may be encountered. The levels of dust mite allergens were measured in 14 offices in response to numerous health complaints. Approximately one-half of the offices investigated were identified as having a dust mite population. Four offices showed levels of Der p I in the dust greater than 1 microgram/g. In two offices, the dust mite allergens were the source of the health complaints. In the other two offices, dust mite allergens were one of the contaminants in the office environment. In all cases, the infestation of dust mites in the offices was localized to a few specific work areas. Office chairs were the primary location where dust mites thrived. The remedial measures included regular cleanup of all fabric-covered office furnishings. Steam cleaning was recommended to eliminate dust mite populations.
authors.affiliation: State of Oregon Occupational Health Laboratory, OR-OSHA Department of Consumer and Business Services, Portland 97214, USA.
authors.forename: M
authors.initials: M
authors.lastname: Janko
authors.forename: D C
authors.initials: DC
authors.lastname: Gould
authors.forename: L
authors.initials: L
authors.lastname: Vance
authors.forename: C C
authors.initials: CC
authors.lastname: Stengel
authors.forename: J
authors.initials: J
authors.lastname: Flack
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D000818:Animals; D039741:Antigens, Dermatophagoides; D002853:Chromatography, Liquid; D004391:Dust / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D006023:Glycoproteins / Q000032:analysis*; D006147:Guanine / Q000032:analysis; D006801:Humans; D008925:Mites; D016273:Occupational Exposure
chemical_list: D039741:Antigens, Dermatophagoides; D004391:Dust; D006023:Glycoproteins; D006147:Guanine