CCK-containing paraneurons in human adenomatous prostate.
The presence of CCK-containing neuroendocrine cells in human adenomatous prostates, and the colocalization of CCK together with serotonin in the same cell, have been demonstrated by means of an immunohistochemical technique and by a double labeling immunofluorescent staining. CCK-containing neuroendocrine cells had a focal distribution in the prostates and sometimes showed dendrite-like cytoplasmic processes. The major part of CCK (96.55%) colocalized with serotonin. CCK probably stimulates muscle contraction and endocrine/exocrine secretions in the urogenital tract.
Cecio
A
A
Dept. of Structures, Functions and Biological Technology, University of Naples, Italy.
Cocca
T
T
Masotti
M T
MT
La Mura
E
E
Vittoria
A
A
D000328:Adult; D002766:Cholecystokinin / Q000032:analysis*; D053379:Chromogranin A; D002864:Chromogranins / Q000032:analysis; D004848:Epithelium / Q000737:chemistry / Q000473:pathology; D005755:Gastrins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009490:Neurosecretory Systems / Q000737:chemistry* / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000378:metabolism* / Q000473:pathology; D012701:Serotonin / Q000032:analysis
D053379:Chromogranin A; D002864:Chromogranins; D005755:Gastrins; D012701:Serotonin; D002766:Cholecystokinin