[The effect of emotional-pain stress on the activity of carboxypeptidase N--the enzyme of neuropeptide processing in the rat brain].
Activity of carboxypeptidase N [correction of H] increased under emotional-algic stress in the rat pituitary gland and hypothalamus. Carboxypeptidase N [correction of H] seems to be involved in development of the stress response, and soluble forms of the enzyme take part in processing of secretory peptides. Membrane-bound forms take part in processing of the neuropeptides specific by their central action.
Gengin
M T
MT
Vernigora
A N
AN
D000818:Animals; D001921:Brain / Q000201:enzymology*; D001923:Brain Chemistry / Q000502:physiology; D002908:Chronic Disease; D001121:Lysine Carboxypeptidase / Q000032:analysis / Q000378:metabolism*; D008297:Male; D009479:Neuropeptides / Q000378:metabolism*; D010146:Pain / Q000201:enzymology*; D010812:Physical Stimulation; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D051381:Rats; D012995:Solubility; D013315:Stress, Psychological / Q000201:enzymology*
D009479:Neuropeptides; D001121:Lysine Carboxypeptidase