Anti-GOR antibodies in lichen planus.
Anti-GOR antibodies characterize patients with autoimmune hepatitis type 2 who are all positive for antibodies to hepatitis C virus (HCV) and have low titers of anti-liver/kidney-microsomal (LKM1) antibody. The documented prevalence of anti-HCV antibodies in patients with lichen planus (LP) and chronic liver disease (CLD) and their negativity for anti-LKM1 antibodies make them eligible for having anti-GOR antibodies. We studied such a possibility in 56 LP patients. Twenty of them had also CLD. Seven CLD patients without LP served as control. Overall, 11/63 patients had anti-GOR antibodies. All of them were anti-HCV positive and had CLD. CLD patients with LP showed the same prevalence of anti-GOR antibodies as CLD patients without LP.
Divano
M C
MC
Department of Dermatology, University of Genoa, Italy.
Parodi
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Rebora
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D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis* / Q000276:immunology; D002908:Chronic Disease; D005260:Female; D006508:Hepatitis Antibodies / Q000032:analysis* / Q000276:immunology; D018937:Hepatitis C Antibodies; D006801:Humans; D007668:Kidney / Q000276:immunology; D008010:Lichen Planus / Q000150:complications / Q000276:immunology*; D008107:Liver Diseases / Q000150:complications / Q000276:immunology*; D008297:Male; D008862:Microsomes, Liver / Q000276:immunology; D008875:Middle Aged; D012189:Retrospective Studies
D001323:Autoantibodies; D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies