Melatonin increases cyclic guanosine monophosphate: biochemical effects mediated by porphyrins, calcium and nitric oxide. Relationships to infant colic and the Sudden Infant Death Syndrome.
It is hypothesized that melatonin, by its actions on porphyrin and nitric oxide biosynthesis, produces an increase in cyclic guanosine monophosphate.
Weissbluth
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D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D002118:Calcium / Q000502:physiology*; D003085:Colic / Q000503:physiopathology*; D006152:Cyclic GMP / Q000096:biosynthesis* / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008550:Melatonin / Q000172:deficiency / Q000502:physiology*; D008954:Models, Biological; D009474:Neurons / Q000201:enzymology / Q000473:pathology; D009569:Nitric Oxide / Q000009:adverse effects / Q000502:physiology*; D019001:Nitric Oxide Synthase; D010528:Peristalsis / Q000502:physiology; D011166:Porphyrins / Q000502:physiology*; D015398:Signal Transduction; D013398:Sudden Infant Death / Q000209:etiology*
D011166:Porphyrins; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D006152:Cyclic GMP; D008550:Melatonin; D002118:Calcium