title: Stereo-EEG of interictal and ictal electrical activity of a histologically proved heterotopic gray matter associated with partial epilepsy.
abstract: Magnetic resonance imaging allows the identification of heterotopic gray matter (HGM) in medically intractable partial epilepsies. The relationships between HGM and the epileptogenic zone remain, however, unclear. In a case of a temporo-parietal epilepsy studied by stereo-EEG, interictal and ictal electrical activity of a temporal HGM were recorded, showing: (1) an intralesional electrical activity, (2) the possible presence of asynchronous spikes, and (3) an early but never initial, or isolated, involvement during ictal discharges. This suggests that the presurgical and surgical management of HGM must be guided, as for other lesions, by the coherence existing between ictal clinical and electrical features, and anatomical data.
authors.affiliation: Department of Neurosciences, CHU Grenoble, France.
authors.forename: S
authors.initials: S
authors.lastname: Francione
authors.forename: P
authors.initials: P
authors.lastname: Kahane
authors.forename: L
authors.initials: L
authors.lastname: Tassi
authors.forename: D
authors.initials: D
authors.lastname: Hoffmann
authors.forename: C
authors.initials: C
authors.lastname: Durisotti
authors.forename: B
authors.initials: B
authors.lastname: Pasquier
authors.forename: C
authors.initials: C
authors.lastname: Munari
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology*; D002828:Choristoma / Q000503:physiopathology*; D004569:Electroencephalography / Q000379:methods; D004828:Epilepsies, Partial / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011379:Prognosis; D013702:Temporal Lobe / Q000473:pathology*