[Action of naftidrofuryl in cerebral neovascularization after cortical lesion in rats].
In this study, naftidrofuryl's action on vascular network regeneration is evaluated after cortical lesion produced by suction. The vascular reaction was analyzed in the region of the damaged cortex and the corresponding contralateral cortex. Comparison of results by variance analysis confirms that the effect of treatment is highly significant (p = 0.008). The results thus obtained show that post-lesion angiogenesis is facilitated and that capacities of post-lesion cerebral function regeneration could also be improved.
Lardot
C
C
Université Catholique de Louvain, Laboratoire de Biologie Cellulaire, Louvain-la-Neuve, Belgique.
Goemaere-Vanneste
J
J
van den Bosch de Aguilar
P
P
D000818:Animals; D001485:Basement Membrane / Q000473:pathology; D001921:Brain / Q000098:blood supply*; D001927:Brain Diseases / Q000188:drug therapy*; D002455:Cell Division; D002540:Cerebral Cortex; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D009257:Nafronyl / Q000494:pharmacology* / Q000627:therapeutic use; D009389:Neovascularization, Pathologic; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D009257:Nafronyl