Cyclic haemopoiesis at 7- or 8-day intervals.
We report a patient with severe anaemia and cyclic oscillations of reticulocyte and leucocyte counts, as well as serum iron (Fe), unsaturated iron-binding capacity (UIBC), ferritin, C-reactive protein (CRP) levels and temperature, at regular intervals of 7 or 8 d. After treatment with prednisolone, anaemia was corrected and the cyclic oscillations of these parameters ceased; whereas treatment with indomethacin, recombinant granulocyte-colony stimulating factor (G-CSF) and erythropoietin (Epo) were unsuccessful.
Sawamura
M
M
Third Department of Internal Medicine, Gunma University School of Medicine, Japan.
Yamaguchi
S
S
Murakami
H
H
Kitahara
T
T
Itoh
K
K
Maehara
T
T
Kawada
E
E
Matsushima
T
T
Tamura
J
J
Naruse
T
T
D000328:Adult; D000740:Anemia / Q000097:blood* / Q000628:therapy; D002097:C-Reactive Protein / Q000032:analysis*; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D005334:Fever / Q000097:blood / Q000209:etiology / Q000628:therapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006410:Hematopoiesis; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D007958:Leukocyte Count; D010507:Periodicity; D010587:Phagocytosis; D011239:Prednisolone / Q000627:therapeutic use; D012156:Reticulocytes / Q000502:physiology
D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D002097:C-Reactive Protein; D011239:Prednisolone; D007213:Indomethacin