Radiation therapy for alveolar soft-part sarcoma.
A clinical experience with radiotherapy in 18 patients with alveolar soft-part sarcoma is presented. Adjuvant radiotherapy was associated with prolonged local control in six of six patients without metastatic disease at diagnosis; later one patient relapsed systematically. Meaningful palliation was achieved in all patients with extra-skeletal (and possibly skeletal) metastatic disease. Radiation therapy may be beneficial for patients with alveolar soft-part sarcoma by enhancing local control achieved with limited surgery, by retarding progression of metastatic deposits, and by providing meaningful palliation.
Sherman
N
N
Department of Radiotherapy, University of Texas Health Sciences Center, M. D. Anderson Cancer Center, Houston 77030.
Vavilala
M
M
Pollock
R
R
Romsdahl
M
M
Jaffe
N
N
D000328:Adult; D001132:Arm; D001365:Axilla; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000556:secondary; D017024:Chemotherapy, Adjuvant; D004550:Elbow; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D010166:Palliative Care; D010386:Pelvic Neoplasms / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012189:Retrospective Studies; D018234:Sarcoma, Alveolar Soft Part / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy