title: Disposition of maternal ketoconazole in breast milk.
abstract: Infant exposure to ketoconazole in human milk was calculated to be 0.4% on average (maximum 1.4%) of those expected from therapeutic doses given directly to infants. Potential risk of adverse reactions from this low exposure level seem to be outweighed by the benefits of breast-feeding.
authors.affiliation: Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: M E
authors.initials: ME
authors.lastname: Moretti
authors.forename: S
authors.initials: S
authors.lastname: Ito
authors.forename: G
authors.initials: G
authors.lastname: Koren
mesh_terms: D000328:Adult; D001942:Breast Feeding; D005260:Female; D006801:Humans; D007223:Infant; D007654:Ketoconazole / Q000493:pharmacokinetics* / Q000627:therapeutic use; D008895:Milk, Human / Q000737:chemistry*; D009181:Mycoses / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D007654:Ketoconazole