Pharmacology and side-effects of interferons.
The distribution, catabolic sites and turnover of interferons are reviewed in order firstly to improve their utilization, secondly to reduce toxicity and thirdly to evaluate alternative routes of administration. In fact catabolic pathways are now seen as a salutary system capable in most cases to reduce toxicity to an acceptable level.
Bocci
V
V
Institute of General Physiology, University of Siena, Italy.
D000818:Animals; D006801:Humans; D007372:Interferons / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology*; D051379:Mice
D007372:Interferons