Bladder carcinoma producing granulocyte colony-stimulating factor.
A patient presented with grade 3 transitional cell carcinoma of the bladder showing a marked increase in granulocyte colony-stimulating factor (G-CSF). G-CSF was identified in the carcinoma by immunohistochemical procedures. The serum and urinary levels of G-CSF were persistently elevated during his clinical course. These results suggest that the carcinoma produced G-CSF and was responsible for its high levels in serum and urine.
Otani
N
N
Department of Urology, School of Medicine, Sapporo Medical University, Japan.
Kumamoto
Y
Y
Tsukamoto
T
T
Satoh
T
T
Sakauchi
F
F
D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000378:metabolism* / Q000473:pathology; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis* / Q000097:blood / Q000652:urine; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000378:metabolism* / Q000473:pathology
D016179:Granulocyte Colony-Stimulating Factor