title: Strategies to improve the outcome of carotid endarterectomy.
abstract: The outcomes of carotid endarterectomy (CEA) including long-term results in 121 patients (126 procedures) were retrospectively analyzed to identify the causes of operative morbidity. The angiographic internal carotid artery (ICA) stenosis was severe (> 70%) in 62 patients and moderate (50-70%) with ulceration in 64. The arterial wall was sutured primarily in 91 patients and with patch graft in 35. The outcomes 3 months after operation were good recovery in 86 patients, moderately disabled in 20, severely disabled in 11, and death in four. Three patients suffered operative morbidity (2.5%). During follow-up, three patients (2.6%) suffered transient ischemic attack on the operative side due to middle cerebral artery stenosis (50%) or ICA occlusion at the origin, and recurrent stenosis (40%) of the common carotid artery and ICA (1 each). In the latter two cases, the artery was primarily sutured. Improved therapeutic results require use of patch vein graft for the arterial wall suture, checking of the CEA patency, and prevention of intracranial ischemic events and hemorrhage due to associated lesions.
authors.affiliation: Department of Neurosurgery, Nara Medical University.
authors.forename: S
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: T
authors.initials: T
authors.lastname: Sakaki
authors.forename: S
authors.initials: S
authors.lastname: Tsunoda
authors.forename: T
authors.initials: T
authors.lastname: Morimoto
authors.forename: T
authors.initials: T
authors.lastname: Hoshida
authors.forename: K
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: H
authors.initials: H
authors.lastname: Iwanaga
authors.forename: Y
authors.initials: Y
authors.lastname: Nikaido
mesh_terms: D000328:Adult; D000368:Aged; D016893:Carotid Stenosis / Q000175:diagnosis / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002546:Ischemic Attack, Transient / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis*; D016896:Treatment Outcome