title: Synaptophysin immunocytochemistry in the regenerating sprouts from the nodes of Ranvier in injured rat sciatic nerve.
abstract: Following crush injury of rat sciatic nerve, strong synaptophysin immunoreactivity was demonstrated in the regenerating sprouts that emerged from the proximal nodes of Ranvier and in their growth cones that extended through the space between Schwann cell basal lamina and myelin sheath of the parent axon. These findings suggest that synaptophysin is involved in the growth regulation of regenerating sprouts.
authors.affiliation: Department of Anatomy, Kobe University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Okajima
authors.forename: A
authors.initials: A
authors.lastname: Mizoguchi
authors.forename: M
authors.initials: M
authors.lastname: Masutani
authors.forename: M
authors.initials: M
authors.lastname: Tomatsuri
authors.forename: K
authors.initials: K
authors.lastname: Tamai
authors.forename: Y
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: C
authors.initials: C
authors.lastname: Ide
mesh_terms: D000818:Animals; D005260:Female; D007150:Immunohistochemistry / Q000379:methods; D008854:Microscopy, Electron; D009409:Nerve Crush; D009416:Nerve Regeneration; D011901:Ranvier's Nodes / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000378:metabolism* / Q000503:physiopathology; D013194:Staining and Labeling; D016708:Synaptophysin / Q000378:metabolism*
chemical_list: D016708:Synaptophysin