[Circulatory hyperkinesis of cirrhosis: etiopathogenesis, clinical and therapeutic implications].
A mysterious complication of cirrhosis is the progressive development of a hyperdynamic circulatory state characterized by high cardiac output and low peripheral and splanchnic arterial resistance. This particular hemodynamic state plays a major role in the progress of portal hypertension and sodium renal retention observed in cirrhosis. In this review, we try to better define the clinical impact and the etiopathogenic mechanism of the hyperdynamic state of cirrhosis.
Denie
C
C
Département de Gastroentérologie, Hôpital de Jolimont, Haine-St-Paul.
Henrion
J
J
D005934:Glucagon / Q000378:metabolism; D006439:Hemodynamics; D006801:Humans; D006975:Hypertension, Portal / Q000503:physiopathology*; D007668:Kidney / Q000378:metabolism; D008103:Liver Cirrhosis / Q000503:physiopathology*; D009569:Nitric Oxide / Q000378:metabolism; D011453:Prostaglandins / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013152:Splanchnic Circulation; D013373:Substance P / Q000378:metabolism
D011453:Prostaglandins; D009569:Nitric Oxide; D013373:Substance P; D005934:Glucagon; D012964:Sodium