[The hierarchy of complexes and compact structures of trivaline with nucleic acids. II. Interaction of trivaline with single-stranded RNA (using poly(U) as an example)].
It has been shown by equilibrium dialysis that at a poly(U) concentration above the "critical" one, the complete polymer saturation with trivaline reaches approximately 0.7, i.e., in these conditions the peptide dimer occupied on poly(U) a site of three bases in length. It has been shown by flow linear dichroism that trivaline beta-dimers preferentially binding with the single-stranded polymer rather than with the double-stranded one. It has been shown by electron microscopy that "the highest" compact structure of trivaline-poly(C) consists of dozens of "biduplex" structures. Beginning with a dimer trivaline-poly(U) complex, we proposed a schematic model for other complexes and compact structures of these molecules.
Strel'tsov
S A
SA
Semenov
T E
TE
Moroz
O V
OV
D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure; D008854:Microscopy, Electron; D011072:Poly U / Q000737:chemistry* / Q000378:metabolism; D011487:Protein Conformation; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D014633:Valine / Q000737:chemistry*
D011072:Poly U; D012313:RNA; D004247:DNA; D014633:Valine