[Psychopharmacological study of two 3-arylsulfonyl 4-hydroxy-coumarines].
The pharmacological study of 3-(4-chlorophenylsulfonyl) 4-hydroxy-7-methoxy- coumarine and 3-(4-methylphenylsulfonyl) 4-hydroxy-7-methoxy-coumarine shows that these derivatives present low sedative effects on the central nervous system, particularly due to their actions upon temperature and motility, more accentuated for the chloro-substituted derivative.
Cheav
S L
SL
Laboratoires de Neuropharmacologie, UFR de Pharmacie, Tours.
Kirkiacharian
S
S
Kurkjian
R
R
Pieri
F
F
Poisson
D
D
D015110:4-Hydroxycoumarins / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003374:Coumarins / Q000494:pharmacology; D004347:Drug Interactions; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011600:Psychopharmacology; D011619:Psychotropic Drugs / Q000494:pharmacology; D014812:Vitamin K / Q000037:antagonists & inhibitors* / Q000494:pharmacology*
D015110:4-Hydroxycoumarins; D003374:Coumarins; D011619:Psychotropic Drugs; D014812:Vitamin K; C068805:4-hydroxycoumarin