title: Double-blind study of nimesulide in divers with inflammatory disorders of the ear, nose and throat.
abstract: 200 divers of either sex, aged 18 to 54 years, entered a double-blind study to compare the efficacy and tolerability of nimesulide 200 mg/day with those of seaprose S 60 mg/day in the treatment of nonbacterial inflammatory disorders of the ear, nose, and throat. At the end of the 1-week treatment period, both drugs were judged to be effective, with improvements and, in most cases, complete remission of all symptoms observed. Nimesulide showed greater clinical efficacy, and both drugs were well tolerated.
authors.affiliation: Medisub (Società Scientifica dei Medici Specialisti in Medicina Subacquea ed Iperbarica) Istituto Iperbarico, Zingonia, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Banchini
authors.forename: I
authors.initials: I
authors.lastname: Scaricabarozzi
authors.forename: U
authors.initials: U
authors.lastname: Montecorboli
authors.forename: A
authors.initials: A
authors.lastname: Ceccarelli
authors.forename: F
authors.initials: F
authors.lastname: Chiesa
authors.forename: L
authors.initials: L
authors.lastname: Ditri
authors.forename: G
authors.initials: G
authors.lastname: Mazzer
authors.forename: R
authors.initials: R
authors.lastname: Moroni
authors.forename: M
authors.initials: M
authors.lastname: Viola
authors.forename: F
authors.initials: F
authors.lastname: Roggia
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004242:Diving; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D010031:Otitis / Q000188:drug therapy*; D010612:Pharyngitis / Q000188:drug therapy*; D012220:Rhinitis / Q000188:drug therapy*; D012697:Serine Endopeptidases / Q000627:therapeutic use*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; C022624:Seaprose S; D012697:Serine Endopeptidases; C012655:nimesulide