Isolation and identification of a FK-506 C36-C37 dihydrodiol from erythromycin-induced rabbit liver microsomes.
Lhoëst
G
G
Department of Pharmaceutical Sciences-UCL, Pharmacokinetics and Metabolism Unit-FATC, Laboratory of Mass Spectrometry, Brussels, Belgium.
Maton
N
N
Laurent
A
A
Verbeeck
R K
RK
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004917:Erythromycin; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008862:Microsomes, Liver / Q000737:chemistry* / Q000187:drug effects; D015394:Molecular Structure; D011817:Rabbits; D016339:Spectrometry, Mass, Fast Atom Bombardment; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000737:chemistry* / Q000378:metabolism
D004917:Erythromycin; D016559:Tacrolimus