[Comparison of proteins, connected with 7SL RNA from dog pancreas and rabbit reticulocytes].
The 7SL RNA has been shown to exist in canine pancreatic cells as specific complexes with proteins and to form RNP-particles dispersed heterogeneously in the range between 12S and 14S. One of the major protein components of those RNPs is a protein of a molecular mass of 85 kDa whose electrophoretic motility is the same as that of the protein detected earlier in SRP-like particles from rabbit reticulocytes. It is assumed that canine pancreatic cells contain SRP-like particles analogous to those discovered in rabbit reticulocytes. Among other proteins, the major ones are evidently high molecular weight SRP subparticles (M = 72, 69 and 54 kDa) differing in electrophoretic motility from SRP-like particles. The proteins detected in the sedimentation region of canine pancreatic SRP have acidic properties and during two-dimensional electrophoresis are distributed at pH varying from 5.5 to 6.5. The protein of SRP-particles is suggested to have neutral properties (pI-7).
Avanesov
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D000818:Animals; D004285:Dogs; D004591:Electrophoresis, Polyacrylamide Gel; D010179:Pancreas / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D016601:RNA-Binding Proteins / Q000378:metabolism*; D011817:Rabbits; D012156:Reticulocytes / Q000378:metabolism*
D016601:RNA-Binding Proteins; D012313:RNA