title: Synchronized sleep oscillations and their paroxysmal developments.
abstract: The state of resting sleep is associated with a series of oscillations generated in cortical and thalamic networks. A newly discovered rhythm groups the spindle and delta sleep oscillations within slowly recurring (< 1 Hz) sequences. Multi-site, extra- and intracellular recordings provide evidence for synchronization of various classes of cell in the neocortex and thalamus during sleep oscillations that might reach paroxysmal levels similar to epileptic states. Sleep oscillations and the underlying synchronizing processes are disrupted during transition to brain arousal.
authors.affiliation: Laboratoire de Neurophysiologie, Faculté de Médecine, Université Laval, Quebec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Steriade
authors.forename: D
authors.initials: D
authors.lastname: Contreras
authors.forename: F
authors.initials: F
authors.lastname: Amzica
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D003700:Delta Rhythm; D004569:Electroencephalography; D006801:Humans; D009991:Oscillometry; D012640:Seizures / Q000209:etiology*; D012890:Sleep / Q000502:physiology*; D013788:Thalamus / Q000502:physiology; D013997:Time Factors