title: Signal transducing mechanisms in interferon action (a brief review).
abstract: Experimental results suggest that protein kinase C (PK-C) may play a substantial role in the action of IFNs, but the precise biochemical pathway remains unknown. Recent evidences reveal the complexity of the mechanism of IFN-action and show that the IFN-alpha, -beta and -gamma induced pathways are overlapping. We briefly discuss what is known in this field and suggest a way in which the contrasting views might be reconciled.
authors.affiliation: Microbiological Research Group, B. Johan National Institute of Hygiene, Budapest, Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Premecz
authors.forename: A
authors.initials: A
authors.lastname: Markovits
authors.forename: I
authors.initials: I
authors.lastname: Földes
mesh_terms: D000818:Animals; D002460:Cell Line; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D051379:Mice; D011493:Protein Kinase C / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D007372:Interferons; D011493:Protein Kinase C