Reverse transcriptase inhibition as prescreen for potential antiviral bioactives.
Extracts from higher plants were evaluated for inhibitory activity against avian myeloblastosis virus reverse transcriptase. The assay may serve as a useful prescreen for potential anti-HIV bioactives.
Antoun
M D
MD
Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico, San Juan 00936-5067.
Ríos
Y R
YR
Mendoza
N T
NT
Proctor
G
G
D000998:Antiviral Agents / Q000494:pharmacology*; D009189:Avian Myeloblastosis Virus / Q000201:enzymology; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D006678:HIV / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D011647:Puerto Rico; D018894:Reverse Transcriptase Inhibitors
D000998:Antiviral Agents; D010936:Plant Extracts; D018894:Reverse Transcriptase Inhibitors