15-Deoxyspergualin inhibits nitric oxide production in the BB/W rat: mechanism for inhibition of islet cell dysfunction in diabetes and transplantation.
Stevens
R B
RB
Department of Surgery, University of Minnesota, Minneapolis.
Lokeh
A
A
Ansite
J D
JD
Rossini
T J
TJ
Sutherland
D E
DE
Mills
C D
CD
D000594:Amino Acid Oxidoreductases / Q000096:biosynthesis*; D000818:Animals; D003208:Concanavalin A; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D004790:Enzyme Induction; D006146:Guanidines / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007515:Islets of Langerhans / Q000187:drug effects / Q000502:physiology*; D016381:Islets of Langerhans Transplantation / Q000276:immunology / Q000502:physiology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects / Q000502:physiology; D009569:Nitric Oxide / Q000037:antagonists & inhibitors*; D019001:Nitric Oxide Synthase; D016133:Polymerase Chain Reaction / Q000379:methods; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis; D051381:Rats; D011913:Rats, Inbred BB; D011916:Rats, Inbred F344; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D006146:Guanidines; D007166:Immunosuppressive Agents; D012333:RNA, Messenger; D003208:Concanavalin A; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; C037258:gusperimus