[Dopaminergic mechanisms of the oculomotor behavior of primates].
Behavioral changes and eye movements were studied through chronic low-dose MPTP exposure (ten intramuscular injections of 0.2 mg/kg per day) in four monkeys (Macaca rhesus). The monkeys developed the deficit of spontaneous saccades and decreased oculomotor range. The vertical component of saccades were hardly reduced. The examination of vestibuloocular reflex revealed no changes (r = approximately 1.0), but the fast phase of nystagmus was blocked.
Shulgovskiĭ
V V
VV
Latanov
A V
AV
Petrov
G V
GV
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000008:administration & dosage; D000293:Adolescent; D000818:Animals; D002648:Child; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D006801:Humans; D008253:Macaca mulatta / Q000502:physiology; D008297:Male; D009801:Oculomotor Muscles / Q000502:physiology*; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology*
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine