title: On establishing the genetic basis of mental disease.
abstract: Many of the recent studies reporting genetic linkages for mental illnesses such as schizophrenia and manic depression have been retracted. The authors of this article argue that the fundamental reason for the difficulties in this research field lies in the strongly held preconceived belief that the primary cause of these illnesses is in fact genetic. All scientists hold preconceived ideas. However, such ideas are more likely to result in erroneous conclusions in the study of human behavior than in other more 'objective' research areas. Moreover, it is especially important that researchers studying human behavior be aware of their biases and learn to compensate for them because of the social consequences of their work.
authors.affiliation: Dept of Chemistry, University of Massachusetts at Boston, 02125.
authors.forename: J S
authors.initials: JS
authors.lastname: Alper
authors.forename: M R
authors.initials: MR
authors.lastname: Natowicz
mesh_terms: D004777:Environment; D008040:Genetic Linkage; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D008957:Models, Genetic; D016017:Odds Ratio; D012941:Social Responsibility