title: Plasmapheresis maintained renal function in an allograft with recurrent membranoproliferative glomerulonephritis type I.
abstract: Six months posttransplant, a 38-year-old woman developed acute renal failure due to recurrent idiopathic membranoproliferative glomerulonephritis (MPGN) type I. MPGN was associated with an elevated rheumatoid factor and IgM deposition in the mesangium. Plasmapheresis with albumin replacement improved and maintained renal function for over a year while cytotoxic agents were administered in an attempt to control the glomerulonephritis. The patient currently has a functional renal allograft 2 years posttransplant.
authors.affiliation: University of Washington, Department of Medicine, Seattle 98195, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Muczynski
mesh_terms: D000328:Adult; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007668:Kidney / Q000503:physiopathology*; D016030:Kidney Transplantation; D010956:Plasmapheresis; D012008:Recurrence; D012217:Rheumatoid Factor / Q000097:blood
chemical_list: D007075:Immunoglobulin M; D012217:Rheumatoid Factor