Insulin-like growth factor (IGF) binding protein-1 is an antigonadotropin: evidence that optimal follicle-stimulating hormone action in ovarian granulosa cells is contingent upon amplification by endogenously-derived IGFs.
Adashi
E Y
EY
Department of Obstetrics, Gynecology, University of Maryland School of Medicine, Baltimore 21201.
Resnick
C E
CE
Rosenfeld
R G
RG
Powell
D R
DR
Koistinen
R
R
Rutanen
E M
EM
Seppala
M
M
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D001667:Binding, Competitive; D002352:Carrier Proteins / Q000378:metabolism* / Q000494:pharmacology*; D002478:Cells, Cultured; D005260:Female; D005640:Follicle Stimulating Hormone / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D006107:Granulosa Cells / Q000187:drug effects / Q000378:metabolism*; D018970:Insulin-Like Growth Factor Binding Protein 1; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D007700:Kinetics; D051381:Rats
D000911:Antibodies, Monoclonal; D002352:Carrier Proteins; D018970:Insulin-Like Growth Factor Binding Protein 1; D007334:Insulin-Like Growth Factor I; D005640:Follicle Stimulating Hormone