title: Human and mouse T-cell-receptor loci: the importance of comparative large-scale DNA sequence analyses.
abstract: It is our belief that large-scale DNA sequencing will revolutionize the study of molecular biology, developmental biology, genetics, and evolution for the TCR gene families and, indeed, all multigene families. We also stress the power of comparative analyses for large-scale DNA sequencing efforts.
authors.affiliation: Department of Molecular Biotechnology, University of Washington, Seattle 98195.
authors.forename: L
authors.initials: L
authors.lastname: Hood
authors.forename: B F
authors.initials: BF
authors.lastname: Koop
authors.forename: L
authors.initials: L
authors.lastname: Rowen
authors.forename: K
authors.initials: K
authors.lastname: Wang
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002874:Chromosome Mapping; D017124:Conserved Sequence; D004247:DNA / Q000235:genetics*; D005809:Genes, Regulator; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D005810:Multigene Family; D011544:Pseudogenes; D012313:RNA / Q000235:genetics; D011948:Receptors, Antigen, T-Cell / Q000235:genetics*; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic; D014362:Trypsinogen / Q000235:genetics
chemical_list: D011948:Receptors, Antigen, T-Cell; D012313:RNA; D014362:Trypsinogen; D004247:DNA