Hyperleukocytosis with marked hypereosinophilia. Morphologic and cytochemical pathologic aspects of eosinophils. Eosinophilic leukaemia?
Excluding the most frequent pathologies that cause hypereosinophilia, we report a case of a patient with hyperleukocytosis and marked hypereosinophilia that showed morphological abnormalities in conjunction with cytochemical pathologic aspects. Physical examination, laboratory results and cytochemical abnormalities induced us, although a normal karyotype, to consider the possibility of eosinophilic leukaemia.
D'Angelo
G
G
Laboratorio di Chimica-Clinica, Ematologia e Microbiologia, Ospedale A. Bellini, Somma Lombardo, Varese.
Giardini
C
C
Calvano
D
D
D000368:Aged; D001856:Bone Marrow Examination; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis; D004804:Eosinophils / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis; D007621:Karyotyping; D007964:Leukocytosis / Q000175:diagnosis; D008297:Male