[Cytokine production by MTSC 4 cells, an established mouse thymic dendritic cell line].
The cytokine production by MTSC 4 cells, a murine thymic dendritic cell line established in our laboratory, has been investigated. Without exogenous stimulation, the MTSC 4 cells constitutively produce multiple types of cytokines, including IL-1, IL-6, IL-7, CSF, IFN and Chemotactic factor (CF). Of which, IL-6 and IFN were abundant: IL-1 and Chemokine, moderate: IL-7 and CSF at low level. MTSC4 cells could not produce detectable either IL-3 of TNF alpha. The establishment of MTSC 4 may be useful in the analysis of the mechanism of thymus selection, and in the study of the network regulation of autocrined cytokines.
Liu
Z G
ZG
Beijing Medical University.
Chen
W F
WF
Cao
L X
LX
Pang
X W
XW
Zhang
P X
PX
Yu
Q
Q
D000818:Animals; D002460:Cell Line; D016207:Cytokines / Q000378:metabolism*; D003713:Dendritic Cells / Q000166:cytology / Q000378:metabolism*; D007372:Interferons / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D013950:Thymus Gland / Q000166:cytology*
D016207:Cytokines; D015850:Interleukin-6; D007372:Interferons