title: Nuclear magnetic resonance methods for studying protein-ligand complexes.
authors.affiliation: Abbott Laboratories, Illinois 60064.
authors.forename: A M
authors.initials: AM
authors.lastname: Petros
authors.forename: S W
authors.initials: SW
authors.lastname: Fesik
mesh_terms: D000591:Amino Acid Isomerases / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D002247:Carbon Isotopes; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism; D016572:Cyclosporine / Q000737:chemistry / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D003903:Deuterium; D006360:Heat-Shock Proteins / Q000737:chemistry / Q000378:metabolism; D006859:Hydrogen; D008024:Ligands; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008958:Models, Molecular; D015335:Molecular Probes; D015394:Molecular Structure; D009587:Nitrogen Isotopes; D019696:Peptidylprolyl Isomerase; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D016559:Tacrolimus / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D022021:Tacrolimus Binding Proteins; D013816:Thermodynamics
chemical_list: D002247:Carbon Isotopes; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D006360:Heat-Shock Proteins; D008024:Ligands; D046911:Macromolecular Substances; D015335:Molecular Probes; D009587:Nitrogen Isotopes; D011506:Proteins; D006859:Hydrogen; D016572:Cyclosporine; D003903:Deuterium; C058028:immunomycin; D000591:Amino Acid Isomerases; D022021:Tacrolimus Binding Proteins; D019696:Peptidylprolyl Isomerase; D016559:Tacrolimus