title: [Urinary bladder nuclear cytology: results of karyometric investigations].
abstract: To assess the value of nuclear morphometry in the cytological diagnosis of urinary bladder carcinoma, washouts of the urinary bladder from 168 patients with histological established bladder cancer were studied. Morphometrical measurements were done on the nuclei of the exfoliated cells. This retrospective study showed that the nuclear parameter obtained by automated image analysis may be helpful in the differential diagnosis between neoplastic and non-neoplastic urinary bladder disease and correlate fairly with the classic histologic grading of malignancy in transitional cell carcinoma of the urinary bladder.
authors.affiliation: Zentrum für Pathologie und urologische Klinik der Philipps Universität Marburg.
authors.forename: A
authors.initials: A
authors.lastname: Bittinger
authors.forename: P
authors.initials: P
authors.lastname: Barth
authors.forename: A
authors.initials: A
authors.lastname: von Keitz
authors.forename: C
authors.initials: C
authors.lastname: Thomas
mesh_terms: D002467:Cell Nucleus / Q000473:pathology* / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000473:pathology; D005188:False Negative Reactions; D006801:Humans; D001743:Urinary Bladder / Q000166:cytology* / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*