Infantile endodermal sinus tumor presenting with vaginal bleeding: report of a case.
Endodermal sinus tumor (EST) of the vagina is extremely rare and primarily affects infants. We report on a six-month-old female infant with EST of the vagina who presented with vaginal spotting of one month's duration. Pelvic ultrasound and computerized tomography showed a 3.8 x 3.5 cm heterogeneous mass between the bladder and the rectum. The serum alpha-fetoprotein (AFP) level was high (1270 ng/mL) and the beta-human chorionic gonadotropin was undetectable. She received surgical intervention followed by chemotherapy. The patient was disease-free and serum AFP remained undetectable during the eight-month follow-up period.
Horng
Y C
YC
Department of Pediatrics, National Taiwan University, Taipei, R.O.C.
Tsai
W Y
WY
Lin
D T
DT
Huang
S F
SF
Lin
K H
KH
Li
Y W
YW
Hsieh
F J
FJ
Chen
C C
CC
D018240:Endodermal Sinus Tumor / Q000175:diagnosis*; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D007223:Infant; D014623:Vaginal Diseases / Q000209:etiology*; D014625:Vaginal Neoplasms / Q000175:diagnosis*; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins