title: SP- and CGRP-immunoreactive axons differ in their ability to reinnervate the skin of the rat tail.
abstract: The reinnervation of cutaneous targets was studied in the rat tail after proximal lesions of all collector nerves. The distribution of immunofluorescent nerve fibres stained for calcitonin-gene-related peptide (CGRP) and substance P (SP) was examined after 110-210 days. Targets at all sites were reinnervated by CGRP-immunoreactive (IR) fibres. However, SP-IR terminals were rare, particularly distally, despite staining within subdermal nerve trunks.
authors.affiliation: Department of Physiology and Pharmacology, University of Queensland, Australia.
authors.forename: E M
authors.initials: EM
authors.lastname: McLachlan
authors.forename: J R
authors.initials: JR
authors.lastname: Keast
authors.forename: M
authors.initials: M
authors.lastname: Bauer
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D015740:Calcitonin Gene-Related Peptide / Q000502:physiology*; D005260:Female; D006197:Hair / Q000294:innervation; D007150:Immunohistochemistry; D008297:Male; D009409:Nerve Crush; D009416:Nerve Regeneration / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000294:innervation*; D013373:Substance P / Q000502:physiology*; D013623:Tail
chemical_list: D013373:Substance P; D015740:Calcitonin Gene-Related Peptide