Pharmacologic treatment of thalassemia intermedia with hydroxyurea.
Three adult patients with beta-thalassemia intermedia were treated with hydroxyurea. Each had a significant but transient rise in total hemoglobin level associated with a variable increase in hemoglobin F.
Hajjar
F M
FM
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut.
Pearson
H A
HA
D000284:Administration, Oral; D000328:Adult; D004909:Erythrocyte Indices / Q000187:drug effects; D005260:Female; D005319:Fetal Hemoglobin / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D017086:beta-Thalassemia / Q000097:blood / Q000188:drug therapy*
D006454:Hemoglobins; D005319:Fetal Hemoglobin; D006918:Hydroxyurea