title: Extramammary Paget's disease associated with prostate adenocarcinoma.
abstract: A case of scrotal and penile extramammary Paget's disease (EMPD) and concurrent prostate adenocarcinoma in a 59-year-old patient is presented. Immunohistochemically, the tumor cells of both the EMPD and prostate stained positively for prostate-specific antigen. Six previously reported cases of EMPD associated with prostate adenocarcinoma are reviewed, along with a discussion of current theories of the pathogenesis of EMPD.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Florida College of Medicine, Gainesville 32610.
authors.forename: J P
authors.initials: JP
authors.lastname: Sleater
authors.forename: M J
authors.initials: MJ
authors.lastname: Ford
authors.forename: B B
authors.initials: BB
authors.lastname: Beers
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010145:Paget Disease, Extramammary / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis
chemical_list: D002272:Carcinoembryonic Antigen; D009418:S100 Proteins; D017430:Prostate-Specific Antigen