Treatment of upper airways inflammation with nimesulide.
Nimesulide treatment for 7 to 10 days is shown to be effective in controlling the inflammatory process in upper airways disorders such as rhinitis, rhinosinusitis, rhinopharyngitis and tubaritis, and in middle ear disorder (secretory otitis media). A concomitant antibacterial is considered necessary in cases involving infection, in order to retain the improvements in mucociliary transport obtained with anti-inflammatory treatment. Nimesulide is also shown to be effective when given in combination with the mucolytic drug ambroxol.
Bellussi
L
L
Cattedra di Clinica ORL, Dipartimento di Medicina Sperimentale, L'Aquila, Italy.
Passàli
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000551:Ambroxol / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000188:drug therapy*; D010612:Pharyngitis / Q000188:drug therapy*; D012220:Rhinitis / Q000188:drug therapy*; D016037:Single-Blind Method; D013449:Sulfonamides / Q000008:administration & dosage / Q000627:therapeutic use*; D014069:Tonsillitis / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; D000551:Ambroxol; C012655:nimesulide