title: [The effect of glucocorticoid hormones on the blood pressure and contractile activity of the mesenteric arteries in rats].
abstract: Methylprednisolone (MP) induced first a decrease and then an increase of the blood pressure in Wistar rats. The hypertensive effect stabilised after three administrations. The contractile response amplitude in electric stimulation of the vascular-motor nerves first increased and then sharply dropped. The glycocorticoids were concluded to reduce the contractile properties of vessels simultaneously increasing the blood pressure.
authors.forename: N M
authors.initials: NM
authors.lastname: Il'ina
authors.forename: A V
authors.initials: AV
authors.lastname: Didenko
authors.forename: V V
authors.initials: VV
authors.lastname: Iazykov
authors.forename: V G
authors.initials: VG
authors.lastname: Shaliapina
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D008297:Male; D008638:Mesenteric Arteries / Q000187:drug effects / Q000502:physiology; D008775:Methylprednisolone / Q000008:administration & dosage / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D008775:Methylprednisolone