title: [Detection of serum antibody of hepatitis C virus in parturients and their newborns].
abstract: Detection of serum antibody of hepatitis C virus (anti-HCV) with ELISA kits was performed in 315 parturients and their newborns. The results indicated that some of the infants, born of mothers infected with HCV were also anti-HCV positive, and a high positive rate of abnormal maternal hepato-function harbored a markedly positive rate of anti-HCV both in mother and newborn and bore a positive correlation to the maternal age. These suggest that besides the five routine tests, anti-HCV should better be determined, especially in mothers with abnormal hepato-function. If possible, in such cases HCV-RNA should be examined by using revert nested polymerase chain reaction technique to determine whether a vertical mother-infant transmission exists.
authors.affiliation: First Teaching Hospital, Bethune University of Medical Sciences, Changchun.
authors.forename: C H
authors.initials: CH
authors.lastname: Li
authors.forename: F Y
authors.initials: FY
authors.lastname: Guo
authors.forename: J
authors.initials: J
authors.lastname: Yue
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000635:transmission*; D018937:Hepatitis C Antibodies; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D049590:Postpartum Period; D011247:Pregnancy
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies