The endodermal sinus tumour and clear cell ovarian cancer.
There are similarities between clear cell epithelial ovarian carcinoma and endodermal sinus tumours. Apart from the morphological and clinical characteristics there are immunohistochemical markers of value in differentiating these 2 tumours and the detection of a raised serum AFP is characteristic of endodermal sinus tumours. These 3 cases we describe show the fallibility of the classical differentiating criteria between these two tumours.
O'Brien
M E
ME
Gynaecological Oncology Unit, Royal Marsden Hospital, London, U.K.
Perren
T
T
Tan
S
S
Fisher
C
C
Wiltshaw
E
E
D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D000328:Adult; D018394:CA-125 Antigen / Q000097:blood; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016256:Lewis X Antigen / Q000032:analysis; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D000509:alpha-Fetoproteins / Q000032:analysis
D018394:CA-125 Antigen; D016256:Lewis X Antigen; D000509:alpha-Fetoproteins