[Synthesis and structural study of 5-arylidene thiazolidine-2,4-diones and 3-substituted-4-thio-imidazolidine-2-ones].
The synthesis and the physico-chemical properties of four 3-(4-bromophenacyl)-5-arylidene-thiazolidine-2,4-diones, two 3-(4-bromobenzyl)-5-arylidene-thiazolidine-2,4-diones and seven 3-(4-chlorobenzyl)-5-arylidene-4-thio-imidazolidine-2-ones were described. These products were synthetized by the aldolisation-crotonisation reaction between aromatic aldehydes and substituted thiazolidinediones or thio-imidazolidinones.
Albuquerque
J F
JF
Departamento de Antibioticos, Universidade Federal de Pernambuco, Brasil.
Azevedo
L C
LC
Galdino
S L
SL
Chantegrel
J
J
Pitta
I R
IR
Luu-Duc
C
C
D001929:Brain Edema / Q000188:drug therapy; D006801:Humans; D007004:Hypoglycemic Agents / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D048289:Imidazolidines; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D045162:Thiazolidinediones
D007004:Hypoglycemic Agents; D007093:Imidazoles; D048289:Imidazolidines; D013844:Thiazoles; D045162:Thiazolidinediones; C004916:ethylene urea; C089946:2,4-thiazolidinedione