Antibacterial activity and phytochemical analysis of Vochysia divergens (Vochysiaceae).
Vochysia divergens Pohl (Vochysiaceae) is a tree commonly found in wet soils of 'Pantanal' of Mato Grosso, Brazil, and used in folk medicine against infections and asthma. We have studied different extracts and some isolated compounds from this plant for antibacterial activity. From the extracts of the stem bark beta-sitosterol, betulinic acid and sericic acid were isolated. The minimal inhibitory concentration (MIC) for Staphylococcus aureus were: ethanolic extract (MIC = 1.5 mg/ml); ethyl acetate extract (MIC = 2.0 mg/ml); and sericic acid (MIC = 1.0 mg/ml). Escherichia coli was resistant until 5 mg/ml.
Hess
S C
SC
Departamento de Ciências do Ambiente, Universidade Federal do Mato Grosso do Sul, Corumbá, Brazil.
Brum
R L
RL
Honda
N K
NK
Cruz
A B
AB
Moretto
E
E
Cruz
R B
RB
Messana
I
I
Ferrari
F
F
Cechinel Filho
V
V
Yunes
R A
RA
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology; D001938:Brazil; D004926:Escherichia coli / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000494:pharmacology; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts / Q000494:pharmacology*; D018547:Plant Stems / Q000378:metabolism; D012855:Sitosterols / Q000302:isolation & purification / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects*; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology; D000094062:Betulinic Acid
D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D012855:Sitosterols; D014315:Triterpenes; C097138:sericic acid; C025473:gamma-sitosterol; D009828:Oleanolic Acid; D000094062:Betulinic Acid