title: The toxicity of antigens extracted from strains of Bacteroides vulgatus from different origins to chicken embryos.
abstract: The toxicity of purified lipopolysaccharides (LPS) and capsular polysaccharides (CPS) extracted from 3 strains of Bacteroides vulgatus to 11 day old chicken embryos was examined. The three B. vulgatus strains were isolated from different sources. The CELD50 (chicken embryos lethal dose 50%) of these preparations was determined. All antigens were shown to be lethal to chick embryos. The toxicity of LPS of the strains isolated from clinical sources was higher than that of the capsular antigens. The LPS and CPS of one strain isolated from normal gut-flora was less toxic than other antigens.
authors.affiliation: Department of Clinical Bacteriology, Medical Academy, Warsaw, Poland.
authors.forename: G S
authors.initials: GS
authors.lastname: Rouyan
authors.forename: F
authors.initials: F
authors.lastname: Meisel-Mikołajczyk
authors.forename: W
authors.initials: W
authors.lastname: Rumin
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000633:toxicity*; D016667:Bacterial Capsules / Q000737:chemistry; D001439:Bacteroides / Q000276:immunology*; D002642:Chick Embryo; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D007928:Lethal Dose 50; D011135:Polysaccharides, Bacterial / Q000633:toxicity*; D013045:Species Specificity
chemical_list: D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial