Aspergillus brain abscess in a patient with normal immunity--case report.
A 53-year-old male with normal immunity presented with Aspergillus brain abscess manifesting as frontal headache. T2-weighted magnetic resonance imaging revealed a hypointense lesion in the left frontal lobe extending into the right frontal lobe. The hypointense appearance on T2-weighted images appears to be characteristic of aspergillosis. Bifrontal craniotomy exposed an elastic-hard mass in the base of the left frontal lobe extending into the right frontal lobe, and into the left ethmoid sinus. The mass contained a cavity with white fluid. The abscess was removed almost totally. The histological diagnosis was Aspergillus abscess. Antibiotic treatment with amphotericin B and fluconazole was given for 2 months postoperatively. No recurrence was identified during 15-month follow-up.
Kawakami
N
N
Department of Neurosurgery, Yamaguchi University School of Medicine.
Nishizaki
T
T
Sugiyama
S
S
Ito
H
H
D000666:Amphotericin B / Q000008:administration & dosage; D001228:Aspergillosis / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D001922:Brain Abscess / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D003131:Combined Modality Therapy; D015725:Fluconazole / Q000008:administration & dosage; D005625:Frontal Lobe / Q000382:microbiology / Q000601:surgery; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D000666:Amphotericin B; D015725:Fluconazole