Exposure of bus and taxi drivers to urban air pollutants as measured by DNA and protein adducts.
Urinary 1-hydroxypyrene, lymphocyte DNA adducts, serum protein-bound PAH and hemoglobin-bound alkene adducts were analysed from 4 groups of non-smoking men: urban and suburban bus drivers, taxi drivers and suburban controls. The only differences between the groups were in DNA adducts between suburban bus drivers and controls, and in DNA adduct and plasma protein PAH-adducts between taxi drivers and controls.
Hemminki
K
K
Center for Nutrition and Toxicology, Karolinska Institute, Novum, Huddinge, Sweden.
Zhang
L F
LF
Krüger
J
J
Autrup
H
H
Törnqvist
M
M
Norbeck
H E
HE
D000393:Air Pollutants / Q000009:adverse effects* / Q000378:metabolism; D000395:Air Pollutants, Occupational / Q000009:adverse effects* / Q000378:metabolism; D001334:Automobile Driving; D001798:Blood Proteins / Q000187:drug effects* / Q000378:metabolism*; D002273:Carcinogens / Q000378:metabolism* / Q000633:toxicity*; D004247:DNA / Q000097:blood / Q000187:drug effects* / Q000378:metabolism*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009153:Mutagens / Q000378:metabolism; D016273:Occupational Exposure; D011083:Polycyclic Compounds / Q000097:blood / Q000378:metabolism / Q000633:toxicity; D011485:Protein Binding; D011721:Pyrenes / Q000378:metabolism; D014507:Urbanization; D001335:Vehicle Emissions
D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D001798:Blood Proteins; D002273:Carcinogens; D009153:Mutagens; D011083:Polycyclic Compounds; D011721:Pyrenes; D001335:Vehicle Emissions; D004247:DNA; C033146:1-hydroxypyrene