Deletion (11)(q14.1q21).
We report on a 4-year-old girl with moderate developmental delay, horseshoe kidney, bilateral duplication of the ureters with right upper pole obstruction, hydronephrosis and nonfunction, and subsequent Wilms tumor of the right lower pole. She had an interstitial deletion of the long arm of chromosome 11 involving the region 11(q14.1q21).
Stratton
R F
RF
South Texas Genetics Center, Southwest Texas Methodist Hospital, San Antonio 78229.
Lazarus
K H
KH
Ritchie
E J
EJ
Bell
A M
AM
D000015:Abnormalities, Multiple / Q000235:genetics*; D002675:Child, Preschool; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002880:Chromosomes, Human, Pair 11 / Q000648:ultrastructure; D002658:Developmental Disabilities / Q000235:genetics; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D007680:Kidney Neoplasms / Q000235:genetics; D014513:Ureter / Q000002:abnormalities; D009396:Wilms Tumor / Q000235:genetics