Mechanism and function of histamine-sodium cotransport by astroglial cells.
There is a saturable and high affinity uptake system for histamine in astroglial cells. The uptake is metabolically driven, sodium dependent and electrogenic. We consider the functional significance of these findings.
Huszti
Z
Z
Department of Pharmacodynamics, Semmelweis University of Medicine, Budapest, Hungary.
D000818:Animals; D001253:Astrocytes / Q000378:metabolism*; D002478:Cells, Cultured; D002642:Chick Embryo; D006632:Histamine / Q000378:metabolism*; D006636:Histamine Release / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000378:metabolism*
D006632:Histamine; D012964:Sodium