The pars defect as a pain source. A histologic study.
METHODS
Tissue from the pars defects of six adult patients with symptomatic spondylolysis and spondylolisthesis was obtained at surgery. A histologic study was conducted to identify and characterize neural elements in this tissue.


OBJECTIVE
To determine if nociceptive nerve endings were present within the pars defect of patients with symptomatic spondylolysis.


BACKGROUND
The origin of back pain in patients with spondylolysis remains uncertain. The defect in the pars interarticularis has been implicated as a possible pain source.


METHODS
The soft tissue from the pars defect was obtained at surgery. A modified gold chloride stain was used to prepare the tissue for histologic examination. Tissue blocks were sectioned and studied under light microscopy.


RESULTS
Neural elements were found in all specimens examined. Free nerve endings believed to have nociceptive function were identified in all specimens. The density of neural elements varied between specimens.


CONCLUSIONS
The finding of neural elements, including free nerve endings within the pars defect tissue, suggests that the pars defect may be a source of back pain in some patients with symptomatic spondylolysis.
Schneiderman
G A
GA
Northern California Spine and Rehabilitation, Sacramento, USA.
McLain
R F
RF
Hambly
M F
MF
Nielsen
S L
SL
D000328:Adult; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000209:etiology* / Q000473:pathology; D008159:Lumbar Vertebrae / Q000294:innervation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009411:Nerve Endings / Q000473:pathology; D013168:Spondylolisthesis / Q000150:complications / Q000473:pathology*; D013169:Spondylolysis / Q000150:complications / Q000473:pathology*