title: A murine monoclonal antibody directed against a yeast cell wall glycoprotein antigen of the yeast genus Saccharomyces.
abstract: Murine monoclonal antibodies (mAbs) were selected against a cell wall glycoprotein of Saccharomyces cerevisiae. One of the mAbs (92-276/018) specifically identified S. cerevisiae and the sibling species S. paradoxus, S. pastorianus and S. bayanus in immunofluorescence studies and immunoblot analyses, while no other yeast genera except Saccharomyces were recognized. Further analysis indicated that the mAb 92-276/018 reacts with an epitope in the carbohydrate chain of the cell wall glycoproteins.
authors.affiliation: Research Laboratories of Behringwerke AG, Marburg, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Bröker
authors.forename: H P
authors.initials: HP
authors.lastname: Harthus
authors.forename: R M
authors.initials: RM
authors.lastname: Barnes
mesh_terms: D000908:Antibodies, Fungal / Q000276:immunology*; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D000946:Antigens, Fungal / Q000276:immunology*; D001667:Binding, Competitive; D002473:Cell Wall / Q000276:immunology*; D000939:Epitopes; D006023:Glycoproteins / Q000276:immunology*; D008351:Mannans / Q000276:immunology; D012440:Saccharomyces / Q000276:immunology*; D013045:Species Specificity
chemical_list: D000908:Antibodies, Fungal; D000911:Antibodies, Monoclonal; D000946:Antigens, Fungal; D000939:Epitopes; D006023:Glycoproteins; D008351:Mannans