[The immunodiagnosis of melioidosis by a solid-phase variant of radioimmunological analysis (RIA)].
A variant of the solid-phase radioimmunoassay (RIA) has been developed for the detection of specific immunoglobulins in laboratory animals infected with Pseudomonas pseudomallei. The proposed method has advantages over the indirect hemagglutination test and the enzyme immunoassay in its sensitivity and specificity. The newly developed RIA variant, based on group-specific antigens 6 + d, makes it possible to classify the strain causing the disease with the Asian or Australian serovar of P. pseudomallei according to the composition of detected immunoglobulins.
Piven'
N N
NN
Manolov
A D
AD
Zykin
L F
LF
Zamarin
A E
AE
Manankov
V V
VV
Iakovlev
A T
AT
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial; D016957:Burkholderia pseudomallei / Q000276:immunology; D006224:Cricetinae; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D006168:Guinea Pigs; D007159:Immunologic Tests / Q000295:instrumentation / Q000379:methods; D008554:Melioidosis / Q000175:diagnosis*; D008647:Mesocricetus; D051379:Mice; D011863:Radioimmunoassay / Q000295:instrumentation / Q000379:methods*; D051381:Rats; D012680:Sensitivity and Specificity
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial