Laron dwarfism in the Arabian Gulf: a report of a sibship.
Laron dwarfism is a rare inherited form of short stature. Most cases reported have been in people of Mediterranean origin, particularly Oriental Jews. We describe the first sibship in an Arab Muslim family from Kuwait in the Arabian Gulf. This type of growth hormone insensitivity is caused by defects in the growth hormone receptor gene. The recently available recombinant human insulin-like growth factor I has shown promise as a promoter of growth in children with Laron syndrome.
Zaki
M
M
Department of Paediatrics, Farwania Hospital, Safat, Kuwait.
Daoud
A S
AS
Ramadan
D G
DG
D000365:Age Determination by Skeleton; D003906:Developing Countries; D004393:Dwarfism, Pituitary / Q000097:blood / Q000235:genetics*; D005260:Female; D013006:Growth Hormone / Q000172:deficiency / Q000235:genetics; D006801:Humans; D007223:Infant; D007334:Insulin-Like Growth Factor I / Q000172:deficiency / Q000235:genetics; D007730:Kuwait; D008297:Male
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone