[Ascites, hydrothorax and ovarian tumor: Meigs' syndrome in a patient with small ovaries and increased CA 125 level].
In a 51-year-old woman with bilateral Brenner tumours of the ovaries and with intermittent hydrothorax and ascites, Meigs' syndrome was diagnosed. The serum CA 125 level was 620 U/ml (normal: 5-35). Bilateral ovariectomy, hysterectomy and omentectomy were carried out. The ovaries were not enlarged. Postoperatively, the pleural effusion and ascites resolved and the CA 125 level decreased to 8.4 U/ml. The pathogenesis of hydrothorax probably involves passage through the diaphragm, and the CA 125 may be produced by the peritoneal lining or by the Brenner tumours.
Cober-Tromp
H A
HA
Rijksuniversiteit Limburg, Faculteit der Geneeskunde, Maastricht.
Kwee
W S
WS
Utama
I
I
Wetzels
L C
LC
D001201:Ascites / Q000209:etiology*; D014408:Biomarkers, Tumor / Q000032:analysis; D018394:CA-125 Antigen / Q000032:analysis; D005260:Female; D006801:Humans; D006876:Hydrothorax / Q000000981:diagnostic imaging / Q000209:etiology*; D008539:Meigs Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D011859:Radiography
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen