Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2.
The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding.
Fernández-Ruiz
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E
Departamento de Immunología, Hospital de la Princesa, Madrid, Spain.
Armesilla
A L
AL
Sánchez-Madrid
F
F
Vega
M A
MA
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018955:CD36 Antigens; D002874:Chromosome Mapping; D002897:Chromosomes, Human, Pair 7; D003094:Collagen / Q000378:metabolism; D006224:Cricetinae; D004247:DNA / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D016023:Integrins / Q000235:genetics*; D008562:Membrane Glycoproteins / Q000378:metabolism; D008969:Molecular Sequence Data; D010980:Platelet Membrane Glycoproteins / Q000235:genetics*; D016133:Polymerase Chain Reaction; D038981:Receptors, Collagen; D016024:Receptors, Cytoadhesin / Q000235:genetics*; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; D019699:Thrombospondins
D018955:CD36 Antigens; D016023:Integrins; D008562:Membrane Glycoproteins; D010980:Platelet Membrane Glycoproteins; D038981:Receptors, Collagen; D016024:Receptors, Cytoadhesin; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; D019699:Thrombospondins; D003094:Collagen; D004247:DNA