title: Amylase-producing Bence Jones multiple myeloma with pancreatitis-like symptoms.
abstract: Amylase-producing tumors are mainly adenocarcinomas and, in rare instances, multiple myelomas. We describe here a first case of amylase-producing Bence Jones type myeloma with pancreatitis-like symptoms and the second in a Caucasian patient. The finding of salivary-type hyperamylasemia in a 72-year-old female with a possible pancreatitis made us suspect the diagnosis. Amylase production was observed in bone marrow cultures in which 96% of cellularity was composed of plasmablasts. Serum amylase level decreased when chemotherapy was given.
authors.affiliation: Department of Hematology, Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Lopez
authors.forename: C
authors.initials: C
authors.lastname: Ulibarrena
authors.forename: P
authors.initials: P
authors.lastname: Gonzalez-Porque
authors.forename: G
authors.initials: G
authors.lastname: Navas
authors.forename: E
authors.initials: E
authors.lastname: Roldan
authors.forename: J A
authors.initials: JA
authors.lastname: Cancelas
authors.forename: J
authors.initials: J
authors.lastname: Perez-Oteyza
authors.forename: C
authors.initials: C
authors.lastname: Burgaleta
authors.forename: J
authors.initials: J
authors.lastname: García-Laraña
authors.forename: J L
authors.initials: JL
authors.lastname: Sastre
mesh_terms: D000368:Aged; D000681:Amylases / Q000096:biosynthesis* / Q000097:blood; D001536:Bence Jones Protein; D001853:Bone Marrow / Q000201:enzymology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000201:enzymology; D010195:Pancreatitis / Q000175:diagnosis*; D010950:Plasma Cells / Q000473:pathology; D012463:Saliva / Q000201:enzymology
chemical_list: D001536:Bence Jones Protein; D000681:Amylases