title: Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome.
abstract: OBJECTIVE
  To evaluate the relationship between antiandrogen withdrawal and change in prostate-specific antigen (PSA) when the antiandrogen in question is other than flutamide.
  
  
  METHODS
  Presented is a case of a patient in whom the antiandrogen casodex was discontinued after clinical progression despite combined androgen blockade.
  
  
  RESULTS
  A transient decline in serum PSA was observed after casodex withdrawal.
  
  
  CONCLUSIONS
  The relationship between antiandrogen withdrawal and a change in PSA may be a general phenomenon, not unique to flutamide.
authors.affiliation: Department of Medicine, University of California, San Francisco.
authors.forename: E J
authors.initials: EJ
authors.lastname: Small
authors.forename: P R
authors.initials: PR
authors.lastname: Carroll
mesh_terms: D000726:Androgen Antagonists; D000813:Anilides; D006801:Humans; D008297:Male; D008875:Middle Aged; D009570:Nitriles; D017430:Prostate-Specific Antigen / Q000097:blood*; D013375:Substance Withdrawal Syndrome / Q000097:blood*; D014105:Tosyl Compounds
chemical_list: D000726:Androgen Antagonists; D000813:Anilides; D009570:Nitriles; D014105:Tosyl Compounds; C053541:bicalutamide; D017430:Prostate-Specific Antigen