title: Regulatory requirement for three dose levels and proof of tissue localisation in rodent genetic toxicity assays--a call for supporting data.
authors.affiliation: Zeneca Central Toxicology Laboratory, Macclesfield, UK.
authors.forename: J
authors.initials: J
authors.lastname: Ashby
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005062:European Union; D017408:Guidelines as Topic; D051379:Mice; D009152:Mutagenicity Tests / Q000592:standards*; D009153:Mutagens / Q000493:pharmacokinetics*; D051381:Rats; D014018:Tissue Distribution
chemical_list: D009153:Mutagens