Convergent synthesis of an octasaccharide fragment of the O-specific polysaccharide of Shigella dysenteriae type 1.
A stereocontrolled, convergent synthesis is described of the linear octasaccharide methyl glycoside alpha-L-Rha p-(1-->2)-alpha-D-Gal p-(1-->3)-alpha-Glc p NAc-(1-->3)-al pha-L-Rha p-(1-->3)-alpha-L-Rha p-(1-->2)-alpha-D-Gal p-(1-->3) -alpha-D-Glc p NAc-(1-->3)-alpha-L-Rha p-OMe (11), which corresponds to two contiguous repeating units of the O-specific polysaccharide of Shigella dysenteriae type 1.
Pozsgay
V
V
Laboratory of Developmental and Molecular Immunity, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Pannell
L
L
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D019081:O Antigens; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D009904:Optical Rotation; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D012762:Shigella dysenteriae / Q000737:chemistry* / Q000276:immunology; D016339:Spectrometry, Mass, Fast Atom Bombardment
D007202:Indicators and Reagents; D019081:O Antigens; D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial