title: Randomized comparison of balloon dilation and transurethral incision for treatment of symptomatic benign prostatic hyperplasia.
abstract: The concept of relieving the symptoms of benign prostatic hyperplasia (BPH) by dilating the urethral has existed for centuries. Thirty patients with a clinically estimated prostate gland size of 25 g or less were randomized to either balloon dilation (BDP) or transurethral incision of the prostate (TUIP). The mean pretreatment Madsen-Iverson symptom scores in the two groups were 15.0 +/- 4.9 (SD) and 15.4 +/- 4.4, respectively. The early response rates were 87% fo BDP and 86% for TUIP, with the mean symptom scores declining to 3.4 +/- 2.8 after dilation and 4.2 +/- 6.6 after incision. Among the 14 patients who initially responded to BDP, 2 have been lost to follow-up, 1 died of unrelated causes at 17 months with no urinary symptoms, 2 remain in response at 32 and 38 months, and the other 9 (75% of those available for evaluation) have developed recurrences. Among the 12 patents who responded to TUIP, 2 have been lost to follow-up, 8 remain in response at 14 to 48 months, and 2 (20%) developed recurrences by 44 months of follow-up. In the short term, both BDP and TUIP are effective for treating bladder outlet obstruction in men with relatively small prostates. However, the effect of dilation appears to be less durable than that of incision.
authors.affiliation: Urology Section, Veterans Affairs Medical Center, Omaha, NE.
authors.forename: R K
authors.initials: RK
authors.lastname: Chiou
authors.forename: J E
authors.initials: JE
authors.lastname: Binard
authors.forename: M E
authors.initials: ME
authors.lastname: Ebersole
authors.forename: J J
authors.initials: JJ
authors.lastname: Horan
authors.forename: Y K
authors.initials: YK
authors.lastname: Chiou
authors.forename: B
authors.initials: B
authors.lastname: Lynch
mesh_terms: D000368:Aged; D002404:Catheterization / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy*; D016896:Treatment Outcome; D014563:Urodynamics