[Prevalence of HBV and HCV infections in plasma donors with recently increased ALT level].
HCV and HBV markers in sera were examined in a group of donors (71 cases) who had a history of elevated ALT, and were compared with another group of blood donors (217 cases) who had no such a history. The results showed that the positive rates in both two groups of donors were 14.08% and 6.45% for anti-HCV, 3/8 and 2/13 for anti-HCV-IgM in anti-HCV positive cases, 2.82% and 0.46% for HBsAg, 32.39% and 25.35% for anti-HBs, 45.07% and 33.18% for anti-HBc, respectively (P < 0.05-0.01). It showed a good correlation between the positive rates of HCV and HBV markers and the times of ALT elevation.
Li
F
F
Clinical Immunology Research Unit, Tongji Hospital, Tongji Medical University, Wuhan.
D000410:Alanine Transaminase / Q000097:blood*; D001782:Blood Donors; D001804:Blood Transfusion, Autologous; D002681:China / Q000453:epidemiology; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology*; D018937:Hepatitis C Antibodies; D006801:Humans; D010956:Plasmapheresis; D015995:Prevalence
D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies; D000410:Alanine Transaminase