title: [Use of intra-arterial chemotherapy in the treatment of malignant tumors in children].
abstract: Transcatheter arterial chemotherapy has been perfected in the treatment of 66 patients with various severe malignant tumors. A total of 75 arterial cytostatic injections were made, out of them 57 were given in primary tumors and 18 in tumor metastases. The children's age ranged from 1 to 14 years. High arterial therapeutic doses in combination with extracorporeal blood purification by hemosorption in the treatment of hepatic metastases yielded 100% efficiency. Prolonged arterial chemotherapy for pulmonary metastases provided an excellent therapeutic effect. Thus, 75 arterial injections of cytostatics gave rise to 32% of complete remissions, 48% of partial remissions. There was no benefit in 20% of cases. Adverse reactions were absent.
authors.forename: S V
authors.initials: SV
authors.lastname: Smirtiukov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Poliaev
authors.forename: V A
authors.initials: VA
authors.lastname: Strykov
authors.forename: V I
authors.initials: VI
authors.lastname: Kovalev
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Goncharov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Nikanorov
authors.forename: A F
authors.initials: AF
authors.lastname: Bukhny
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001859:Bone Neoplasms / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007261:Infusions, Intra-Arterial; D007680:Kidney Neoplasms / Q000188:drug therapy; D008113:Liver Neoplasms / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents