[The use of DNA probes for the diagnosis of pulmonary tuberculosis].
Mycobacterium-specific nonradioactive DNA probes have been tested able to detect mycobacteria in clinical samples (sputum, bronchoalveolar lavage) for 48 hours. The probes sensitivity makes up 1000-10,000 cells. Molecular hybridization confirms the results of DNA-probe diagnostic conclusion of tuberculosis more frequently than the results of standard microbiological tests.
Khomenko
A G
AG
Korneev
A A
AA
Lazarenko
V N
VN
Korneev
M A
MA
Proskriakova
O V
OV
Grishina
T D
TD
D000328:Adult; D001249:Asthma / Q000175:diagnosis; D002648:Child; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics; D003937:Diagnosis, Differential; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics; D009693:Nucleic Acid Hybridization; D012329:RNA, Bacterial / Q000235:genetics; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis*
D015342:DNA Probes; D004269:DNA, Bacterial; D012329:RNA, Bacterial