Mediastinal germ cell tumors. A continuing odyssey.
Mediastinal germ cell tumors are rare, and in the past they were uniformly lethal. A high index of suspicion leading to early diagnosis combined with modern interdisciplinary management can now prolong comfortable survival and produce many cures. The development of Cis-Platinum based combination chemotherapy, and its early use, has been the major factor in the improvement of treatment results.
Golbey
R B
RB
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D018237:Germinoma / Q000097:blood / Q000188:drug therapy / Q000401:mortality; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008479:Mediastinal Neoplasms / Q000097:blood / Q000188:drug therapy / Q000401:mortality; D018239:Seminoma / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality; D015996:Survival Rate; D000509:alpha-Fetoproteins / Q000032:analysis
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D007770:L-Lactate Dehydrogenase; D002945:Cisplatin