Localisation of substance P-like immunoreactivity in the ciliary ganglia of monkey (Macaca fascicularis) and cat: a light- and electron-microscopic study.
The present study describes substance P-like immunoreactivity in the ciliary ganglia of monkey (Macaca fascicularis) and cat. About 60% of neurons in the monkey ciliary ganglion and 40% in the cat ciliary ganglion were substance P-like immunoreactive, ranging from faint to moderate staining. Substance P-like immunoreactivity was located in cell bodies, dendritic profiles and axons. In the monkey, substance P-like immunoreactive pericellular arborisations were associated with about 0.5%-3% of the ganglion cells, which were either negatively, faintly or moderately stained. An electron-microscopic study demonstrated the presence of either substance P-like immunoreactive positive or negative axon terminals synapsing or closely associated with positive dendritic profiles in both the monkey and cat ciliary ganglia. The results suggest that substance P plays an important role in the ciliary ganglion, perhaps as a modulator or transmitter.
Zhang
Y L
YL
Department of Anatomy, National University of Singapore, Kent Ridge.
Tan
C K
CK
Wong
W C
WC
D000818:Animals; D002415:Cats; D005260:Female; D005726:Ganglia, Parasympathetic / Q000737:chemistry* / Q000648:ultrastructure; D005728:Ganglia, Sympathetic / Q000737:chemistry / Q000648:ultrastructure; D008252:Macaca fascicularis / Q000033:anatomy & histology*; D008297:Male; D008636:Mesencephalon / Q000737:chemistry / Q000648:ultrastructure; D008854:Microscopy, Electron; D013373:Substance P / Q000032:analysis* / Q000276:immunology*
D013373:Substance P