title: Acute zinc chloride ingestion in a child: local and systemic effects.
abstract: A 16-month-old boy ingested liquid zinc chloride/ammonium chloride soldering flux. He developed severe local burns, metabolic acidosis, hepatic damage, hyperamylasemia, lethargy, and hypertension. Peak measured plasma zinc was 1,199 micrograms/dL. Because of persistent signs of systemic toxicity, he was chelated with dimercaprol (BAL) and EDTA. Although clinical improvement was noted coincident with the initiation of chelation, there was no apparent increase in urinary zinc excretion. Scarring in the gastric antrum necessitated an antrectomy. The child recovered without other apparent complications.
authors.affiliation: Rocky Mountain Poison and Drug Center, Denver General Hospital, University of Colorado Health Sciences Center, Colorado.
authors.forename: P E
authors.initials: PE
authors.lastname: McKinney
authors.forename: J
authors.initials: J
authors.lastname: Brent
authors.forename: K
authors.initials: K
authors.lastname: Kulig
mesh_terms: D000138:Acidosis / Q000139:chemically induced; D000208:Acute Disease; D000643:Ammonium Chloride / Q000097:blood / Q000506:poisoning* / Q000652:urine; D000681:Amylases / Q000097:blood; D002057:Burns, Chemical / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D056486:Chemical and Drug Induced Liver Injury; D002712:Chlorides / Q000097:blood / Q000506:poisoning* / Q000652:urine; D004112:Dimercaprol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004492:Edetic Acid / Q000627:therapeutic use; D004636:Emergency Service, Hospital; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007223:Infant; D008297:Male; D011041:Poisoning / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D011706:Pyloric Antrum / Q000293:injuries*; D012894:Sleep Stages; D017967:Zinc Compounds / Q000097:blood / Q000506:poisoning* / Q000652:urine
chemical_list: D002712:Chlorides; D017967:Zinc Compounds; D000643:Ammonium Chloride; D004112:Dimercaprol; C016837:zinc chloride; D004492:Edetic Acid; D000681:Amylases