title: Treatment of clinically fixed lymph node metastases from carcinoma of the penis by chemotherapy and surgery.
abstract: A 59-year-old patient with carcinoma of the penis was referred for therapy of clinically fixed and ulcerated bilateral inguinal lymphadenopathies. He was treated initially by partial penectomy and subsequently by weekly infusions of methotrexate, bleomycin and cisplatin. This treatment resulted in a decrease in the size of bilateral, lymphadenopathy and re-epithelization of the overlying ulcer. Subsequently a left-sided inguinal lymphadenectomy was performed. At follow-up 18 months later the symptoms had disappeared and no distant metastases were observed.
authors.affiliation: Department of Urology, Ankara State Hospital, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Germiyanoğlu
authors.forename: K
authors.initials: K
authors.lastname: Horasanli
authors.forename: D
authors.initials: D
authors.lastname: Erol
authors.forename: U
authors.initials: U
authors.lastname: Altug
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D007264:Inguinal Canal; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D010412:Penile Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D001761:Bleomycin; D002945:Cisplatin; D008727:Methotrexate