title: [The role of iloprost in vascular surgery].
abstract: Use of prostanoids in vascular surgery is valuable in various conditions: intra and postoperatively, during limb salvage procedures, they are useful to lower peripheral resistances, and in patients with limited gangrene, when surgery is not feasible, they improve limb blood flow. After some years of subjective clinical evaluation, multicentric randomized clinical trials started; the aim was to quantify the real benefit derived from the use of prostanoids to the evolution of limb ischemia and to the improvement of results of surgical revascularization. We have not yet definitive results; preliminary data show a better immediate patency rate of femoro-distal bypass grafts and a critical reduction in long term limb amputations.
authors.affiliation: Istituto di Chirurgia Vascolare e Angiologia, Università degli Studi di Milano.
authors.forename: G
authors.initials: G
authors.lastname: Agrifoglio
authors.forename: L
authors.initials: L
authors.lastname: Gabrielli
authors.forename: A
authors.initials: A
authors.lastname: Sarcina
authors.forename: F
authors.initials: F
authors.lastname: Bonalumi
mesh_terms: D002986:Clinical Trials as Topic; D016638:Critical Illness; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D007430:Intraoperative Care; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D016879:Salvage Therapy
chemical_list: D016285:Iloprost