title: Evaluation of monoclonal anti-glycophorin B as an unusual anti-S.
abstract: BACKGROUND
  Monoclonal antibody 148 is a murine monoclonal anti-glycophorin B that preferentially reacts with S+ human red cells.
  
  
  METHODS
  Serologic and immunochemical studies were performed using red cells with various phenotypes.
  
  
  RESULTS
  These studies reveal that this monoclonal antibody is unusual in that it fails to agglutinate S+ TSEN+ red cells and agglutinates S- St(a+) and S- Dantu+ red cells.
  
  
  CONCLUSIONS
  These results allow the prediction of the glycophorin composition of GP.Hop (Mi.IV) red cells.
authors.affiliation: International Blood Group Reference Laboratory, SW Regional Transfusion Centre, Bristol, UK.
authors.forename: N J
authors.initials: NJ
authors.lastname: Hemming
authors.forename: M E
authors.initials: ME
authors.lastname: Reid
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000939:Epitopes; D004910:Erythrocyte Membrane / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D005069:Evaluation Studies as Topic; D006021:Glycophorins / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D015151:Immunoblotting; D007519:Isoantigens / Q000276:immunology*; D008951:MNSs Blood-Group System / Q000276:immunology*; D051379:Mice; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary
chemical_list: D000911:Antibodies, Monoclonal; D000939:Epitopes; D006021:Glycophorins; D007519:Isoantigens; D008951:MNSs Blood-Group System