title: Existence of an optimum expression level for secretion of foreign proteins in yeast.
authors.affiliation: Department of Chemical Engineering, University of Illinois, Urbana 61801.
authors.forename: K D
authors.initials: KD
authors.lastname: Wittrup
authors.forename: A S
authors.initials: AS
authors.lastname: Robinson
authors.forename: R N
authors.initials: RN
authors.lastname: Parekh
authors.forename: K J
authors.initials: KJ
authors.lastname: Forrester
mesh_terms: D007611:Aprotinin / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D001692:Biological Transport; D003001:Cloning, Molecular / Q000379:methods*; D004721:Endoplasmic Reticulum; D004921:Erythropoietin / Q000096:biosynthesis / Q000378:metabolism; D015966:Gene Expression Regulation, Fungal; D005813:Genes, Synthetic; D005822:Genetic Vectors; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis / Q000378:metabolism; D016297:Mutagenesis, Site-Directed; D010957:Plasmids; D010982:Platelet-Derived Growth Factor / Q000096:biosynthesis / Q000378:metabolism; D017510:Protein Folding; D011499:Protein Processing, Post-Translational; D011993:Recombinant Fusion Proteins / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D013997:Time Factors
chemical_list: D010982:Platelet-Derived Growth Factor; D011993:Recombinant Fusion Proteins; D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D007611:Aprotinin