title: Comparison of nimesulide and diclofenac in the prevention and treatment of painful inflammatory postoperative complications of general surgery.
abstract: In a double-blind study, 40 patients scheduled for saphenectomy or inguinal hernioplasty were randomly assigned to treatment with nimesulide (200mg 3 times daily) or diclofenac (100mg 3 times daily) administered rectally. Therapy with either drug resulted in significantly less pain, oedema and hyperaemia, and resolution of mild fever. No adverse reactions attributable to treatment were observed.
authors.affiliation: Servizio di Anestesia, Rianimazione e Terapia del Dolore, Ospedale di Abbiategrasso, Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ramella
authors.forename: V
authors.initials: V
authors.lastname: Costagli
authors.forename: M
authors.initials: M
authors.lastname: Vetere
authors.forename: C
authors.initials: C
authors.lastname: Capra
authors.forename: G
authors.initials: G
authors.lastname: Casella
authors.forename: A
authors.initials: A
authors.lastname: Sogni
authors.forename: I
authors.initials: I
authors.lastname: Scaricabarozzi
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004008:Diclofenac / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; D004008:Diclofenac; C012655:nimesulide