[Interferon as a stimulator of DNA repair in patients with xeroderma pigmentosum].
Natural leucocyte interferon (IF) upon injection to two patients affected with Xeroderma pigmentosum for three weeks stimulated the inhibited DNA replication and Host reactivation at the level of healthy donors. Tigasol--the drug used traditionally for the treatment of diseases caused by Xeroderma pigmentosum proved less effective than IF.
Zasukhina
G D
GD
L'vova
G N
GN
Chekova
V V
VV
Prokhorov
A Iu
AIu
Mordovtsev
V N
VN
D015112:4-Nitroquinoline-1-oxide / Q000633:toxicity; D004260:DNA Repair / Q000187:drug effects*; D005050:Etretinate / Q000627:therapeutic use; D006579:Heterozygote; D006801:Humans; D007372:Interferons / Q000627:therapeutic use*; D016296:Mutagenesis / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays; D012901:Variola virus / Q000187:drug effects / Q000235:genetics / Q000528:radiation effects; D014983:Xeroderma Pigmentosum / Q000235:genetics* / Q000628:therapy*
D015112:4-Nitroquinoline-1-oxide; D005050:Etretinate; D007372:Interferons