title: Larsen syndrome in siblings with consanguineous parents.
abstract: Two siblings with Larsen syndrome and consanguineous parents are described, both with multiple joint dislocations and the typical facial appearance. Short stature is marked in both children and one had a diaphragmatic hernia which has not been previously described in this condition.
authors.affiliation: Department of Paediatrics, College of Medicine, Blantyre, Malawi.
authors.forename: J M
authors.initials: JM
authors.lastname: Topley
authors.forename: E
authors.initials: E
authors.lastname: Varady
authors.forename: G G
authors.initials: GG
authors.lastname: Lestringant
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D003241:Consanguinity; D002658:Developmental Disabilities / Q000235:genetics; D005145:Face / Q000002:abnormalities*; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007596:Joints / Q000002:abnormalities*; D008297:Male; D013577:Syndrome