title: Fas antigen mRNA induction in postischemic murine brain.
abstract: Fas antigen mRNA induction in the brain was examined using a transient global cerebral ischemia model in BALB/C mice. Northern blot analysis revealed little Fas antigen mRNA expression in the brains of sham-operated mice. A marked induction of Fas mRNA expression was detected in the brains of mice 6 h after 30 min of cerebral ischemia. These results suggest a possible apoptotic mechanism for cell death, mediated by the Fas antigen, in postischemic brain.
authors.affiliation: Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Matsuyama
authors.forename: R
authors.initials: R
authors.lastname: Hata
authors.forename: M
authors.initials: M
authors.lastname: Tagaya
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Nakajima
authors.forename: J
authors.initials: J
authors.lastname: Furuyama
authors.forename: A
authors.initials: A
authors.lastname: Wanaka
authors.forename: M
authors.initials: M
authors.lastname: Sugita
mesh_terms: D000818:Animals; D000954:Antigens, Surface / Q000235:genetics*; D017209:Apoptosis / Q000276:immunology*; D001483:Base Sequence; D004195:Disease Models, Animal; D002546:Ischemic Attack, Transient / Q000276:immunology*; D008297:Male; D008565:Membrane Proteins / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000096:biosynthesis*; D011956:Receptors, Cell Surface / Q000276:immunology*; D019014:fas Receptor
chemical_list: D000954:Antigens, Surface; D008565:Membrane Proteins; D012333:RNA, Messenger; D011956:Receptors, Cell Surface; D019014:fas Receptor