title: Clinical and laboratorial features of visceral toxocariasis in infancy.
abstract: Forty children with a diagnosis of Visceral Toxocariasis were evaluated prospectively from February 1982 to June 1989. Diagnosis was established by clinical, laboratory and serological (ELISA - ES Toxocara canis antigen) evaluations. A great clinical polymorphism was found in our patients, ranging from unspecific or absent manifestations to an exuberant symptomatology. The laboratory findings were: leukocytosis, eosinophilia and elevation of serum gammaglobulin and isohemagglutinin levels. No significant relationship between clinical findings and laboratory parameters was found. Serology (ELISA) was a method of great diagnostic support but did not show a correlation with clinical and laboratory findings in this study. There was a significant relationship between pulmonary manifestations and the presence of signs and/or symptoms, when the patients were sent to us. Our findings, especially the high incidence of pulmonary manifestations, suggest that Visceral Toxocariasis has to be included in the differential diagnostic of children with pulmonary manifestations, characteristic epidemiological data and associated eosinophilia.
authors.affiliation: Department of Pediatrics of the Hospital das Clínicas of the University of São Paulo, Medical School, Brasil.
authors.forename: C M
authors.initials: CM
authors.lastname: Jacob
authors.forename: A C
authors.initials: AC
authors.lastname: Pastorino
authors.forename: B A
authors.initials: BA
authors.lastname: Peres
authors.forename: E O
authors.initials: EO
authors.lastname: Mello
authors.forename: Y
authors.initials: Y
authors.lastname: Okay
authors.forename: G W
authors.initials: GW
authors.lastname: Oselka
mesh_terms: D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications; D005260:Female; D006388:Hemagglutinins / Q000097:blood; D006801:Humans; D007223:Infant; D007816:Larva Migrans, Visceral / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D007964:Leukocytosis / Q000150:complications; D008297:Male; D011446:Prospective Studies; D005719:gamma-Globulins / Q000032:analysis
chemical_list: D006388:Hemagglutinins; D005719:gamma-Globulins