title: Depressed hepatic dihydropyrimidine dehydrogenase activity and fluorouracil-related toxicities.
authors.affiliation: Hôpital Tenon, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Stéphan
authors.forename: M C
authors.initials: MC
authors.lastname: Etienne
authors.forename: C
authors.initials: C
authors.lastname: Wallays
authors.forename: G
authors.initials: G
authors.lastname: Milano
authors.forename: F
authors.initials: F
authors.lastname: Clergue
mesh_terms: D000230:Adenocarcinoma / Q000201:enzymology; D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000378:metabolism; D001927:Brain Diseases / Q000139:chemically induced* / Q000201:enzymology; D002430:Cecal Neoplasms / Q000201:enzymology; D042943:Dihydrouracil Dehydrogenase (NADP); D005260:Female; D005472:Fluorouracil / Q000009:adverse effects* / Q000378:metabolism; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000201:enzymology* / Q000556:secondary; D010088:Oxidoreductases / Q000378:metabolism*; D015275:Tumor Lysis Syndrome / Q000201:enzymology / Q000209:etiology*
chemical_list: D000964:Antimetabolites, Antineoplastic; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil