title: In vivo cytogenetic analyses of the carbamate pesticides Dithane M-45 and Baygon in mice.
abstract: Two carbamate pesticides, Dithane M-45 and Baygon, were analysed for their cytogenetic effects using meiotic chromosome analysis and the micronucleus test in Swiss albino male mice. The three sub-lethal doses of 1687.5, 3375 and 5962.5 mg/kg bw of Dithane M-45 and 1250, 2500 and 3750 mg/kg bw of Baygon were employed in all the experiments. The results demonstrate that neither Dithane M-45 nor Baygon could induce a significant (P > 0.05) increase in the number of chromosomal aberrations in the germ cells or in the percentage of micronuclei in erythrocytes.
authors.affiliation: Department of Studies in Zoology, University of Mysore, India.
authors.forename: V
authors.initials: V
authors.lastname: Vasudev
authors.forename: N B
authors.initials: NB
authors.lastname: Krishnamurthy
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D016009:Chi-Square Distribution; D002869:Chromosome Aberrations; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D008344:Maneb / Q000031:analogs & derivatives* / Q000633:toxicity; D008540:Meiosis / Q000187:drug effects; D051379:Mice; D015162:Micronucleus Tests; D008938:Mitosis / Q000187:drug effects; D001074:Propoxur / Q000633:toxicity*; D013093:Spermatogonia / Q000187:drug effects*; D015038:Zineb / Q000031:analogs & derivatives* / Q000633:toxicity
chemical_list: D007306:Insecticides; D008344:Maneb; C011453:dithane M-45; D001074:Propoxur; D015038:Zineb