Combination adrenaline and ethanolamine endoscopic injection therapy does not impair peptic ulcer healing.
The acute effects of endoscopic injection therapy given for bleeding peptic ulcer and the impact of injection therapy upon peptic ulcer healing were assessed in 70 patients randomized to conservative treatment or injection with a combination of 1:100,000 adrenaline and 5% ethanolamine. Injection was not associated with acute complications nor did it affect the endoscopic findings 48 hours after injection. Ulcer healing on standard doses of H2 receptor drugs was 95% in injected patients and 93% in conservatively treated patients at 6 weeks.
Rajgopal
C
C
Gastrointestinal Unit, Western General Hospital, Edinburgh, UK.
Amin
J
J
Palmer
K R
KR
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D004837:Epinephrine / Q000008:administration & dosage*; D019856:Ethanolamine; D004983:Ethanolamines / Q000008:administration & dosage*; D005773:Gastroscopy; D006801:Humans; D007267:Injections; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000473:pathology / Q000628:therapy*; D015911:Sclerotherapy
D004983:Ethanolamines; D019856:Ethanolamine; D004837:Epinephrine