title: [Determinants of homologous blood utilization in addition to autologous blood transfusion--a multivariate study].
abstract: Since April 1989, we have been using autologous blood donation in order to avoid homologous blood transfusion as much as possible. To determine the factors which influence the necessity for homologous blood transfusion as well as autologous blood donation. Of them 77.6% (group 1) required autologous blood only, but others needed homologous blood transfusion as well as autologous blood. Using an invert analysis, preoperative factors that showed significant differences were age, body weight, number of autologous blood donations, amount of donated autologous blood, preoperative Hb and Ht. Among operative factors, aortic cross clamping time, cardiopulmonary bypass time, amount of concentrated blood from CPB circuit, amount of transfused autologous blood and amount of drainage demonstrated significant differences between groups. Univariately significant factors were studied by multivariate discriminant analysis. Total amount of drainage proved to be the best contributor of non-homologous blood transfusion surgery, followed by preoperative Hb, body weight, amount of concentrated blood from CPB circuit and amount of donated autologous blood in order of contribution Understanding these factors, homologous blood transfusion requirement may be greatly reduced. This is thought to be the largest series of autologous blood donation in Japan.
authors.affiliation: Department of Thoracic Surgery, Juntendo University, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yamamuro
authors.forename: K
authors.initials: K
authors.lastname: Kudou
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoda
authors.forename: M
authors.initials: M
authors.lastname: Nukariya
authors.forename: S
authors.initials: S
authors.lastname: Sasaguri
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: S
authors.initials: S
authors.lastname: Yuasa
mesh_terms: D000704:Analysis of Variance; D001793:Blood Preservation / Q000379:methods; D001804:Blood Transfusion, Autologous; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D005260:Female; D006400:Hematocrit; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D006895:Hydroxyethyl Starch Derivatives