title: Localization of the genetic defect in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1) to the CD40 ligand gene.
authors.affiliation: Division of Immunology, Children's Hospital, Boston, MA.
authors.forename: R
authors.initials: R
authors.lastname: Fuleihan
authors.forename: N
authors.initials: N
authors.lastname: Ramesh
authors.forename: F S
authors.initials: FS
authors.lastname: Rosen
authors.forename: R S
authors.initials: RS
authors.lastname: Geha
mesh_terms: D000293:Adolescent; D015703:Antigens, CD / Q000378:metabolism; D000944:Antigens, Differentiation, B-Lymphocyte / Q000378:metabolism; D019013:CD40 Antigens; D023201:CD40 Ligand; D002648:Child; D002675:Child, Preschool; D004252:DNA Mutational Analysis; D004406:Dysgammaglobulinemia / Q000150:complications / Q000235:genetics* / Q000276:immunology; D015870:Gene Expression; D008040:Genetic Linkage; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000235:genetics* / Q000276:immunology; D017098:IgA Deficiency / Q000150:complications / Q000235:genetics / Q000276:immunology; D017099:IgG Deficiency / Q000150:complications / Q000235:genetics / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood*; D066298:In Vitro Techniques; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics* / Q000378:metabolism; D010375:Pedigree; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D013601:T-Lymphocytes / Q000276:immunology; D014960:X Chromosome
chemical_list: D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D019013:CD40 Antigens; D007075:Immunoglobulin M; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D023201:CD40 Ligand