[The role of capsaicin-sensitive afferent nerves in regulating carbohydrate metabolism in the liver].
Stimulation of afferent neurons with capsaicin enhanced the glycogen phosphorylase activity and decreased the glycogen contents in the rat liver. The glucose concentration in the blood serum was risen. Neurotoxic doses of capsaicin also enhanced the glycogen phosphorylase activity, more obviously so in adult rats. Preliminary administration of the toxic doses of capsaicin somewhat diminished the stimulating effect of capsaicin.
Spiridonov
V K
VK
D000818:Animals; D000831:Animals, Newborn; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D002211:Capsaicin / Q000494:pharmacology* / Q000633:toxicity; D050260:Carbohydrate Metabolism; D004305:Dose-Response Relationship, Drug; D008099:Liver / Q000187:drug effects* / Q000294:innervation / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D009475:Neurons, Afferent / Q000187:drug effects* / Q000502:physiology; D006005:Phosphorylases / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D008112:Liver Glycogen; D006005:Phosphorylases; D002211:Capsaicin