[Prevalence of HBV surface antigens, anti-HBD and anti-HCV antibodies in patients with virus-related chronic liver disease].
In the present study, we investigated Hepatitis B virus (HBV), Hepatitis C virus (HCV), and Hepatitis D virus (HDV) status in patients with chronic liver diseases seen in the period of 1990-1992 using enzyme-linked immunosorbent assay (ELISA) kits. There were 126 male and 64 female patients with a mean age of 42.3 years (range 17-70). Of the 198 patients, 68 (35.7%) had evidence of HCV infection. One hundred and twenty-three patients (64.7%) were positive for hepatitis B surface antigen (HBsAg). Of the 123 HBsA positive patients, 35 (28.4%) were positive for Anti-HDV. Fourteen patients were negative for markers of both HCV and HBV. Liver histology showed persistent hepatitis in 31 patients (16.3%), chronic active hepatitis in 77 (40.6%). Cirrhosis was diagnosed in 82 patients (43.1%). Our results indicate that HCV infection plays a role in chronic liver disease especially where the etiology appears obscure.
Ozyilkan
E
E
Hacettepe Universitesi, Tip Fakültesi Gastroenteroloji Unitesi.
Tatar
G
G
Köseoğlu
T
T
Ozkuyumcu
C
C
Kayhan
B
B
Telatar
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000276:immunology; D002908:Chronic Disease; D003673:Defective Viruses / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology*; D018937:Hepatitis C Antibodies; D003699:Hepatitis D / Q000453:epidemiology*; D003698:Hepatitis Delta Virus / Q000276:immunology; D035923:Hepatitis delta Antigens; D006521:Hepatitis, Chronic / Q000209:etiology; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000209:etiology; D008107:Liver Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence
D000956:Antigens, Viral; D006508:Hepatitis Antibodies; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies; D035923:Hepatitis delta Antigens; C442244:hepatitis delta virus large antigen