Biomonitoring of nurses handling antineoplastic drugs.
The micronuclei analysis in exfoliated cells of the buccal cavity was employed in the cytogenetic monitoring of nurses handling antineoplastic drugs. The group under study consisted of 25 subjects who showed a marked increase in micronucleated cells as compared with the control group (Chi-square = 15.12, with one degree of freedom, P < 0.001).
Machado-Santelli
G M
GM
Depto. Histologia & Embriologia, Universidade de São Paulo, Brazil.
Cerqueira
E M
EM
Oliveira
C T
CT
Pereira
C A
CA
D000328:Adult; D000970:Antineoplastic Agents / Q000633:toxicity*; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008297:Male; D015162:Micronucleus Tests; D008875:Middle Aged; D009055:Mouth / Q000166:cytology / Q000187:drug effects; D009726:Nurses; D016273:Occupational Exposure; D012907:Smoking
D000970:Antineoplastic Agents