Attachment and entry of infectious pancreatic necrosis virus (IPNV) into CHSE-214 cells.
Infectious pancreatic necrosis virus (IPNV) attaches to CHSE-214 cells through two types of cell components: specific and non-specific ones. Competition experiments with inactivated IPNV showed that IPNV requires specific components to productively infect cells. Just a low amount of adsorbed IPNV enters the cell. After 20 minutes, part of the adsorbed IPNV was internalized into acid compartments. Also, the viruses adsorbed on the cell surface require similar periods of time to escape from the neutralization of antibodies.
Kuznar
J
J
Laboratorio de Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Chile.
Soler
M
M
Farias
G
G
Espinoza
J C
JC
D000818:Animals; D018059:Birnaviridae / Q000254:growth & development*; D018175:Birnaviridae Infections / Q000503:physiopathology*; D002478:Cells, Cultured; D004705:Endocytosis; D005399:Fishes / Q000382:microbiology*; D009500:Neutralization Tests; D012367:RNA, Viral / Q000096:biosynthesis; D013997:Time Factors
D012367:RNA, Viral