Virus strategies for evasion of the host response to infection.
The attack on viruses and virus-infected cells by the mammalian immune system has provided considerable selective pressure for viruses that have evolved vigorous countermeasures to pre-empt, neutralize or evade this host attack. These countermeasures are astonishingly diverse, and their study imparts fundamental information about immunology and the mechanisms enabling viruses to survive and cause disease.
Smith
G L
GL
Sir William Dunn School of Pathology, University of Oxford, UK.
D000818:Animals; D003169:Complement Inactivator Proteins / Q000378:metabolism*; D016207:Cytokines / Q000037:antagonists & inhibitors* / Q000378:metabolism; D015395:Histocompatibility Antigens Class I / Q000378:metabolism*; D006801:Humans; D007372:Interferons / Q000037:antagonists & inhibitors*; D014774:Virulence; D014777:Virus Diseases / Q000276:immunology / Q000382:microbiology*; D014780:Viruses / Q000378:metabolism / Q000472:pathogenicity*
D003169:Complement Inactivator Proteins; D016207:Cytokines; D015395:Histocompatibility Antigens Class I; D007372:Interferons