Common acute lymphoblastic leukaemia-lymphoma expressing cytokeratin: a case report.
This report presents a case of common acute lymphoblastic leukaemia-lymphoma expressing low molecular weight cytokeratin but no leukocyte common antigen (CD45) in a 57-year-old man. The unusual morphology and clinical course together with the aberrant immunohistochemical results suggested a diagnosis of undifferentiated carcinoma. A detailed immunohistochemistry study on frozen and paraffin sections and molecular analysis prevented a diagnostic mistake.
Menestrina
F
F
Istituto di Anatomia Patologica, Università di Verona, Italy.
Lestani
M
M
Scarpa
A
A
Viale
G
G
Bonetti
F
F
Pizzolo
G
G
Chilosi
M
M
D000911:Antibodies, Monoclonal; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism*; D017493:Leukocyte Common Antigens / Q000378:metabolism; D008223:Lymphoma / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism* / Q000473:pathology
D000911:Antibodies, Monoclonal; D007633:Keratins; D017493:Leukocyte Common Antigens