title: [Anti-Jo-1-positive polymyositis with interstitial alveolitis and pericardial effusion. Overview of 3 years treatment].
abstract: We describe the case of a 53-year-old woman who developed polymyositis with extramuscular complications: interstitional lung fibrosis, pericarditis and a pericardial effusion, polyarthritis, Raynaud's syndrome, carpal tunnel syndrome, sclerodactylia and positive anti-Jo-1-antibodies. We treated her for 3 years. Pericarditis and pericardial effusion with a fibrosing lung alveolitis were the first clinical manifestations of positive Jo-1-syndrome. We stress the patient's serious cardiac disease accompanied by pericardial effusion, which has seldom been described in specialist articles. Steroid treatment induced remission of the disease, but the Jo-1-antibodies did not disappear from the patient's serum.
authors.affiliation: Abteilung für Innere Medizin-Rheumatologie, Lehrklinik Maribor, Slowenien.
authors.forename: I
authors.initials: I
authors.lastname: Krajnc
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood*; D001327:Autoimmune Diseases / Q000188:drug therapy* / Q000276:immunology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010490:Pericardial Effusion / Q000188:drug therapy* / Q000276:immunology; D017285:Polymyositis / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000008:administration & dosage*; D011658:Pulmonary Fibrosis / Q000188:drug therapy* / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; C046750:Jo-1 antibody; D011239:Prednisolone