title: Chronic ocular ischemia associated with the Eisenmenger's syndrome.
abstract: We studied the ocular findings of two adult patients with the Eisenmenger's syndrome who had atrial septal defects that were diagnosed before the age of 10 years but not operated on and pulmonary hypertension. Both eyes of these patients showed microaneurysms, multiple small blot hemorrhages, or capillary dilation in the temporal peripheral fundus. Multiple microaneurysms and retinal collaterals were confirmed by fluorescein angiography. One of the patients developed bilateral rubeosis iridis with slow progression. These retinal lesions and the rubeosis iridis are probably related to chronic ocular ischemia caused by chronic systemic hypoxia.
authors.affiliation: Department of Ophthalmology, Yodogawa Christian Hospital, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Harino
authors.forename: M
authors.initials: M
authors.lastname: Motokura
authors.forename: N
authors.initials: N
authors.lastname: Nishikawa
authors.forename: M
authors.initials: M
authors.lastname: Fukuda
authors.forename: A
authors.initials: A
authors.lastname: Sasaoka
authors.forename: J E
authors.initials: JE
authors.lastname: Grunwald
mesh_terms: D000328:Adult; D000783:Aneurysm / Q000209:etiology; D002908:Chronic Disease; D004541:Eisenmenger Complex / Q000150:complications*; D005123:Eye / Q000098:blood supply*; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000150:complications / Q000209:etiology; D007498:Iris / Q000098:blood supply; D007511:Ischemia / Q000209:etiology*; D009389:Neovascularization, Pathologic / Q000209:etiology; D012161:Retinal Artery; D012166:Retinal Hemorrhage / Q000209:etiology