title: Vein, silastic, and polyglycolic acid fine mesh: a comparative study in peripheral nerve repair.
abstract: We investigated three sheathing materials (autogenous vein, silastic, and polyglycolic acid fine mesh) using the rat model. Forty rats were divided into five groups of eight animals each. Group A animals underwent transection of the sciatic nerve but had no repair. In Group B, a standard epineural repair was performed. In Groups C, D, and E, the nerve was repaired as in Group B with the addition of autogenous vein, Silastic, and polyglycolic acid fine mesh sheaths, respectively. Nerve regeneration and function were assessed using sciatic functional index, nerve conduction studies, and light microscopy. Sheathing methods showed no statistically significant advantage to standard epineural repair without a sheath.
authors.affiliation: Department of Orthopaedic Surgery, University of South Alabama, Mobile, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Lolley
authors.forename: W J
authors.initials: WJ
authors.lastname: Bose
authors.forename: F
authors.initials: F
authors.lastname: Bastian
authors.forename: B
authors.initials: B
authors.lastname: Bassam
authors.forename: F N
authors.initials: FN
authors.lastname: Meyer
authors.forename: L D
authors.initials: LD
authors.lastname: Anderson
mesh_terms: D000818:Animals; D008297:Male; D009416:Nerve Regeneration; D009431:Neural Conduction; D010525:Peripheral Nerves / Q000033:anatomy & histology / Q000502:physiology / Q000601:surgery*; D011100:Polyglycolic Acid; D051381:Rats; D017207:Rats, Sprague-Dawley; D012826:Silicone Elastomers; D013526:Surgical Mesh; D014182:Transplantation, Autologous; D014680:Veins
chemical_list: D012826:Silicone Elastomers; D011100:Polyglycolic Acid