title: [Common mechanisms of cardiac damage and adaptation in ischemia and reperfusion (components for the construction of the general theory of cardiac pathology)].
abstract: The paper deals with the common cellular and molecular mechanisms responsible for the development of cardiac abnormalities of various genesis. These include changes in cardiomyocytic energy supply processes; physicochemical states and structures of their membranes, in myocardial cell enzymatic activity, intra- and extracellular concentrations and ratios of ions to fluid, in cardiomyocytic electrophysiological parameters, their genetic programme and/or mechanisms of its implementation, in cardiac neurohumoral regulation. It also outlines the specific intra- and extracardiac mechanisms of adaptation of the heart in its lesion of various origin.
authors.forename: P F
authors.initials: PF
authors.lastname: Limvitskiĭ
mesh_terms: D000818:Animals; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology*; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology*