[The assessment of the interferon status of term newborns born to mothers with chronic nonspecific lung diseases].
The study involved 34 full-term newborn babies born by mothers with chronic nonspecific diseases of the lungs and 10 newborns born by mothers with the physiological course of pregnancy and parturition, the examinations being carried out in the early neonatal period. A lower capacity for production of endogenous and gamma-interferons at delivery and on day 6 of life as well as a higher incidence of intrauterine and postnatal infections were observed in the newborns of the first group. This indicated the necessity to consider such babies as a group at risk of developing neonatal complications. The data of the study may be used for early diagnosis and prognosis of perinatal infections.
Malinovskaia
V V
VV
Saliaeva
M V
MV
Ovechko-Filippova
L N
LN
Kuz'menko
L E
LE
D000328:Adult; D000375:Aging / Q000276:immunology; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn / Q000276:immunology*; D007232:Infant, Newborn, Diseases / Q000276:immunology; D007372:Interferons / Q000097:blood*; D008173:Lung Diseases, Obstructive / Q000276:immunology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
D007372:Interferons