title: The endodermal sinus tumour and clear cell ovarian cancer.
abstract: There are similarities between clear cell epithelial ovarian carcinoma and endodermal sinus tumours. Apart from the morphological and clinical characteristics there are immunohistochemical markers of value in differentiating these 2 tumours and the detection of a raised serum AFP is characteristic of endodermal sinus tumours. These 3 cases we describe show the fallibility of the classical differentiating criteria between these two tumours.
authors.affiliation: Gynaecological Oncology Unit, Royal Marsden Hospital, London, U.K.
authors.forename: M E
authors.initials: ME
authors.lastname: O'Brien
authors.forename: T
authors.initials: T
authors.lastname: Perren
authors.forename: S
authors.initials: S
authors.lastname: Tan
authors.forename: C
authors.initials: C
authors.lastname: Fisher
authors.forename: E
authors.initials: E
authors.lastname: Wiltshaw
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D000328:Adult; D018394:CA-125 Antigen / Q000097:blood; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016256:Lewis X Antigen / Q000032:analysis; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D018394:CA-125 Antigen; D016256:Lewis X Antigen; D000509:alpha-Fetoproteins