title: Calculation of contributions of individual monomeric units to biopolymer function.
abstract: The possibility of determination of individual monomeric unit contributions into biopolymer function based on the data on biopolymer primary structures and functional activities is discussed. We show that even the most complete set of data do not allow to determine the absolute contributions of monomeric units, while their relative contributions may be determined.
authors.affiliation: Institute of Mathematical Problems in Biology, Russian Academy of Sciences, Pushchino, Moscow Region.
authors.lastname: Ogurtsov AYu
authors.lastname: Elkin YuE
authors.forename: S A
authors.initials: SA
authors.lastname: Shabalina
mesh_terms: D000818:Animals; D001704:Biopolymers; D004247:DNA / Q000502:physiology*; D008433:Mathematics; D008956:Models, Chemical; D009705:Nucleosides / Q000502:physiology*; D012313:RNA / Q000502:physiology*
chemical_list: D001704:Biopolymers; D009705:Nucleosides; D012313:RNA; D004247:DNA