title: CT-guided needle biopsy of intracranial tumours: results in 118 consecutive patients.
abstract: The purpose of this paper is to evaluate the efficacy and safety of CT-guided needle biopsies and to determine the optimal indications for this technique. The case histories of 118 patients who underwent a CT-guided biopsy for brain lesions during a six-year period, from November 1986 to September 1992, were reviewed. During a preliminary CT-scan, the entry site was determined and localized using a radio opaque marker and the safest route to the lesion was chosen. One hundred and thirty four procedures were performed in 118 patients. A positive diagnosis of tumour was obtained in 106 patients (89.8%). Repeat procedures were required in 18 patients. High-grade gliomas were the more common lesions (55.1%). Morbidity and mortality was assessed over the 30-day period after the procedure. Nine patients died during this time. Eight patients from day 3 to day 30 in the expected course of their disease and one within 48 first hours from neurological deterioration following the procedure. We found that CT-scan guided biopsies are a safe and accurate way to obtain brain tissue specimens for pathological diagnosis in selected cases. For superficial and large tumours it is a simple, fast and effective procedure.
authors.affiliation: Service de Radiologie, Hôpital Neurologique et Neurochirurgical Pierre Wertheimer, Lyon, France.
authors.forename: J
authors.initials: J
authors.lastname: Duquesnel
authors.forename: F
authors.initials: F
authors.lastname: Turjman
authors.forename: M
authors.initials: M
authors.lastname: Hermier
authors.forename: Y
authors.initials: Y
authors.lastname: Bascoulergue
authors.forename: A
authors.initials: A
authors.lastname: Jouvet
authors.forename: G
authors.initials: G
authors.lastname: Gervesy
authors.forename: P
authors.initials: P
authors.lastname: Tournut
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000295:instrumentation*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000401:mortality / Q000473:pathology* / Q000556:secondary; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D015996:Survival Rate; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*