title: Massive locally extensive prostate cancer.
abstract: A massive, locally extensive adenocarcinoma of the prostate (2,246 ccm) presenting as constipation and a palpable abdominal mass, was treated with androgen deprivation resulting in a 94 percent reduction in tumor size, and relief of symptoms. Serum prostate-specific antigen was reduced from 4,029 to 0.4 ng/mL, after hormonal therapy was combined with radiation treatments for local disease control.
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor.
authors.forename: T A
authors.initials: TA
authors.lastname: Rozanski
authors.forename: G J
authors.initials: GJ
authors.lastname: Faerber
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D000368:Aged; D003131:Combined Modality Therapy; D003248:Constipation / Q000209:etiology; D005485:Flutamide / Q000627:therapeutic use; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use; D008297:Male; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D011879:Radiotherapy Dosage
chemical_list: D005485:Flutamide; D017430:Prostate-Specific Antigen; D016729:Leuprolide