title: Melatonin increases cyclic guanosine monophosphate: biochemical effects mediated by porphyrins, calcium and nitric oxide. Relationships to infant colic and the Sudden Infant Death Syndrome.
abstract: It is hypothesized that melatonin, by its actions on porphyrin and nitric oxide biosynthesis, produces an increase in cyclic guanosine monophosphate.
authors.forename: M
authors.initials: M
authors.lastname: Weissbluth
mesh_terms: D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D002118:Calcium / Q000502:physiology*; D003085:Colic / Q000503:physiopathology*; D006152:Cyclic GMP / Q000096:biosynthesis* / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008550:Melatonin / Q000172:deficiency / Q000502:physiology*; D008954:Models, Biological; D009474:Neurons / Q000201:enzymology / Q000473:pathology; D009569:Nitric Oxide / Q000009:adverse effects / Q000502:physiology*; D019001:Nitric Oxide Synthase; D010528:Peristalsis / Q000502:physiology; D011166:Porphyrins / Q000502:physiology*; D015398:Signal Transduction; D013398:Sudden Infant Death / Q000209:etiology*
chemical_list: D011166:Porphyrins; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D006152:Cyclic GMP; D008550:Melatonin; D002118:Calcium