[The role of a gastrin-like peptide in regulating the different stages in the feeding behavior of snails].
The role of gastrin-like peptides in a regulation of feeding behaviour was studied in a snail Helix lucorum. Sensory stimulation during 15 min carried out by a patch of clothes moistened by the carrot juice (pseudo-feeding) decreased the weight (by 25-50%) of eaten carrot and the duration of the food intake. Similar satiety effect was found after pentagastrin (380 ng) or cholecystokinin-octapeptide (560 ng) injection 20 min after the beginning of the food intake. Measurement of the gastrin-like immunoreactivity showed that the peptide levels in the meta-cerebral ganglia and the haemolymph were dependent on the stage of feeding behaviour. After pseudo-feeding the peptide levels in the ganglia and the haemolymph were significantly higher than those during feeding. Our results suggest the presence of a single gastrin/cholecystokinin-like peptide with feeding stage-dependent functional significance in Helix snails.
Shevëlkin
A V
AV
Gromova
N V
NV
Shumova
E A
EA
D000818:Animals; D019835:FMRFamide; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D017952:Ganglia, Invertebrate / Q000737:chemistry / Q000187:drug effects; D005755:Gastrins / Q000032:analysis / Q000187:drug effects / Q000502:physiology*; D006372:Helix, Snails / Q000187:drug effects / Q000502:physiology*; D006458:Hemolymph / Q000737:chemistry / Q000187:drug effects; D009479:Neuropeptides / Q000494:pharmacology; D010418:Pentagastrin / Q000494:pharmacology; D012528:Satiety Response / Q000187:drug effects / Q000502:physiology; D012844:Sincalide / Q000494:pharmacology; D013373:Substance P / Q000494:pharmacology; D013997:Time Factors
D005755:Gastrins; D009479:Neuropeptides; D013373:Substance P; D019835:FMRFamide; D010418:Pentagastrin; D012844:Sincalide