[Effect of various cytologic preparation techniques on form, texture and densitometric nuclear parameters of normal and dysplastic bladder urothelial cells].
An important prerequisite for densitometric and morphometric measurements on cytological specimens is the standardized cell preparation. Optimal results can only be achieved when the analyses are carried out on a regular monolayer of cell nuclei. Comparing the conventional cytological smear with a new centrifugation technique we demonstrate statistically significant differences of the two methods in texture, size and parameters describing the DNA content of normal and dysplastic urothelial cells.
Oberholzer
M
M
Institut für Pathologie der Universität Basel.
Hubler
M
M
Hell
M
M
Spieler
P
P
Oestreicher
M
M
D002467:Cell Nucleus / Q000473:pathology* / Q000648:ultrastructure*; D004247:DNA / Q000032:analysis; D004847:Epithelial Cells; D004848:Epithelium / Q000473:pathology; D011230:Precancerous Conditions / Q000473:pathology; D012016:Reference Values; D001743:Urinary Bladder / Q000166:cytology* / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology
D004247:DNA