Electron microscopic evidence that cortical terminals make direct contact onto cells of the thalamic reticular nucleus in the monkey.
Injections of WGA-HRP were made into somatosensory cortex to determine whether or not the cortex makes monosynaptic connections with neurons of the thalamic reticular nucleus. Two classes of synaptic profiles making asymmetric contacts onto small dendrites were labeled. The first class was small, and contained densely packed vesicles and few mitochondria. The second, larger class contained loosely packed vesicles, several mitochondria, and accounted for approximately one-third of labeled contacts.
Williamson
A M
AM
Department of Anatomy, University of California at San Francisco 94143-0452.
Ohara
P T
PT
Ralston
H J
HJ
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D006735:Horseradish Peroxidase; D008252:Macaca fascicularis; D008854:Microscopy, Electron; D009474:Neurons / Q000502:physiology*; D017729:Presynaptic Terminals / Q000502:physiology*; D013787:Thalamic Nuclei / Q000166:cytology / Q000502:physiology* / Q000648:ultrastructure; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase