The acute phase response.
Adult mammals respond to tissue damage by implementing the acute phase response, which comprises a series of specific physiological reactions. This review outlines the principal cellular and molecular mechanisms that control initiation of the tissue response at the site of injury, the recruitment of the systemic defense mechanisms, the acute phase response of the liver and the resolution of the acute phase response.
Baumann
H
H
Dept of Molecular and Cell Biology, Roswell Park Cancer Institute, Buffalo, NY 14263.
Gauldie
J
J
D000209:Acute-Phase Proteins / Q000276:immunology; D000210:Acute-Phase Reaction / Q000276:immunology*; D000818:Animals; D006801:Humans; D008099:Liver / Q000276:immunology
D000209:Acute-Phase Proteins