title: Symptoms in schizophrenic syndromes in relation to age, sex, duration of illness and number of previous hospitalizations.
abstract: In studies by means of the Swedish version of the Positive and Negative Syndrome Scale, we have demonstrated a 5-factor model of schizophrenia, including positive, negative, excited, anxious/depressive and cognitive factors. In this study, the 5 factors were correlated with background factors in a series comprising 140 patients with schizophrenic syndromes. None of the 5 factors revealed any significant age or sex differences. The positive factor correlated positively with the number of previous hospitalizations and the negative factor correlated negatively. The excited factor correlated negatively with age at onset, age at first hospitalization and positively with the duration of the illness and the number of previous hospitalizations. The cognitive factor correlated negatively with age at onset and age at first hospitalization and positively with the duration of the illness. Age at onset was positively correlated with delusions, excitement, unusual thought content and poor impulse control and negatively with lack of spontaneity. The duration of illness correlated positively with excitement, difficulty in abstract thinking and mannerisms. The number of previous hospitalizations correlated positively with delusions, excitement, unusual thought content and poor impulse control and significant negative correlations were demonstrated as concerns blunted affect and lack of spontaneity.
authors.affiliation: Department of Psychiatry, University Hospital, Uppsala, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Lindström
authors.forename: L
authors.initials: L
authors.lastname: von Knorring
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006801:Humans; D007555:Isoxazoles / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D010880:Piperidines / Q000627:therapeutic use; D018967:Risperidone; D016713:Ritanserin / Q000627:therapeutic use; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy / Q000534:rehabilitation; D012565:Schizophrenic Psychology; D012737:Sex Factors
chemical_list: D014150:Antipsychotic Agents; D007555:Isoxazoles; D010880:Piperidines; D016713:Ritanserin; D006220:Haloperidol; D018967:Risperidone