[A clinicopathologic study of 15 cases of collecting duct carcinoma of the kidney].
Fifteen cases of papillary adenocarcinoma of the kidney are presented. The lesions were polycystic in gross appearance. Histologically, they were subdivided into three types: papillary cystadenocarcinoma, papillary oncocytic cystadenocarcinoma and papillary mucinous cystadenocarcinoma. Immunohistochemically, the tumor cells demonstrated positive reactivity for high molecular weight keratin and glandular lumina membrane positivity for EMA, which support a collecting duct origin for the tumor. Most of the tumors were large (average diameter 9.6 cm) and invasion of perinephric tissues was observed in 80% of the cases, an indication of its aggressive behavior. As most of the tumors occurred in the medulla and invaded the collecting ducts, the clinical manifestations were different from those of renal cell carcinomas.
Li
Y T
YT
Sichuan Provincial People's Hospital, Chengdu.
D000293:Adolescent; D000328:Adult; D002648:Child; D018282:Cystadenocarcinoma, Mucinous / Q000737:chemistry / Q000473:pathology*; D018283:Cystadenocarcinoma, Papillary / Q000737:chemistry / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology*; D007685:Kidney Tubules, Collecting; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness
D007633:Keratins