title: A Macintosh program for the versatile generation of random nucleic acid sequences and their structural analysis.
abstract: The program 'MacStAn' for the Apple Macintosh generates random sequences and can analyze their tendency to form secondary structure or translation products as well as their mono-, di- and trinucleotide composition. Generation of random sequences is versatile in that one can (i) predefine the G+C content, maximal base repetitions and constant regions; (ii) preset the entire dinucleotide composition; or (iii) shuffle an existing sequence. The program constitutes an integrated package with a graphical user interface, full-featured editing, saving, printing, text import and export, dot plot and sequence alignment.
authors.affiliation: Abteilung Viroidforshung, Max-Planck-Institut für Biochemie, Planegg-Martinsried, Germany.
authors.forename: F U
authors.initials: FU
authors.lastname: Gast
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000235:genetics; D005069:Evaluation Studies as Topic; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry / Q000235:genetics; D016053:RNA, Protozoan / Q000235:genetics; D011897:Random Allocation; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D013768:Tetrahymena / Q000235:genetics
chemical_list: D016053:RNA, Protozoan; D012313:RNA; D004247:DNA