title: [Clinical and experimental observations of buzhong yiqi decoction in the treatment of chronic hepatitis B].
abstract: A clinical observation of Buzhong Yiqi decoction (BZYQD) and Western medicine was used on a matched control in treating chronic hepatitis B. The result showed that BZYQD was significantly better than the Western medicine in improving clinical symptoms and signs, the liver function and serological test of hepatitis B antigen-antibody system (HBAg-Ab system), P < 0.05. In order to explore the therapeutical mechanism of BZYQD, the study of the effects of which on synthesis of hepatic DNA, RNA and protein in mice were performed too. The results showed that BZYQD had marked promotive effects on the synthesis of hepatic DNA, RNA and protein. It was considered that the mechanism of anti-hepatitis effects might related to the enhancing protein synthesis in liver, promoting the repairs of the damaged liver tissue and improving the defense function of organism as a whole.
authors.affiliation: En-shi Medical Training School.
authors.forename: F B
authors.initials: FB
authors.lastname: Du
authors.forename: R J
authors.initials: RJ
authors.lastname: Wang
authors.forename: T Y
authors.initials: TY
authors.lastname: Shao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D004247:DNA / Q000096:biosynthesis; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy* / Q000378:metabolism; D006521:Hepatitis, Chronic / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008297:Male; D051379:Mice; D008875:Middle Aged; D012313:RNA / Q000096:biosynthesis
chemical_list: D004365:Drugs, Chinese Herbal; D012313:RNA; D004247:DNA