[The oxytocinergic neurosecretory system in genetically selected rats differing by their emotionality. Morphometric research].
The rats selectively bred for rapid (KHA) and slow (KLA) acquisition of the avoidance response were subjected to inescapable shock (IS). Synthesis and secretion of oxytocin (OT) were higher in intact KLA rats as compared to KHA ones. Preliminary exposure to IS resulted in opposite changes of the OT synthesis and secretion. The findings suggest a dependence of the stress-reactivity of the OT-ergic system on the copying of the behaviour strategy.
Zhukov
D A
DA
Chernigovskaia
E V
EV
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D002466:Cell Nucleolus / Q000502:physiology / Q000648:ultrastructure; D003214:Conditioning, Classical / Q000502:physiology; D004644:Emotions / Q000502:physiology*; D007031:Hypothalamus / Q000502:physiology / Q000648:ultrastructure; D008297:Male; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure; D009490:Neurosecretory Systems / Q000502:physiology / Q000648:ultrastructure*; D010121:Oxytocin / Q000096:biosynthesis / Q000378:metabolism; D010904:Pituitary Gland, Posterior / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains / Q000502:physiology*; D018045:Receptors, Oxytocin / Q000502:physiology / Q000648:ultrastructure*; D012641:Selection, Genetic
D018045:Receptors, Oxytocin; D010121:Oxytocin