[Correction of disorders of cardiac electric stability in post-infarction cardiosclerosis using a diet enriched with polyunsaturated fatty acids].
In a 14-20 days after feeding of rats with "eikonole" (cod-liver oil, deduced from skeletal muscle and enriched by eicosapentaenic and docosahexaenic fatty acids). Myocardial infarction by Selie has been induced and in a 30 days of the same feeding, contractile function and heart electrical stability in situ have been investigated. Eikonole increased heart fibrillation threshold by 50%, decreased the frequency of spontaneous extrasystole in 3 times and ectopic activation (extrasystole), induced by n. vagus stimulation, in 2.5 times. Eikonole increased the intensity of structures' functioning in the state of relative physiological rest, but did not influence essentially on pressure and the velocity of myocardial contraction and weakening.
Meerson
F Z
FZ
Belkina
L M
LM
Fu
S Ts
STs
Isaev
V A
VA
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000178:diet therapy* / Q000209:etiology / Q000503:physiopathology; D005117:Cardiac Complexes, Premature / Q000517:prevention & control; D003060:Cod Liver Oil / Q000627:therapeutic use; D005231:Fatty Acids, Unsaturated / Q000627:therapeutic use*; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D009203:Myocardial Infarction / Q000150:complications / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D012598:Sclerosis
D005231:Fatty Acids, Unsaturated; D003060:Cod Liver Oil