title: Evidence of xenon transport through the gramicidin channel: a 129Xe-NMR study.
abstract: Evidence is presented for Xe transport through the gramicidin A channel. This evidence for Xe transport through gramicidin A channels has been obtained using 129Xe-NMR spectroscopy. Three experiments were utilized. The first experiment involved monitoring the change in the chemical shift of 129Xe in the presence of increasing gramicidin A concentration, the second observed the effect on the 129Xe chemical shift with gramicidin A channels photochemically altered by UV light and the third determined the effect of gramicidin A channels blocked by Ba2+ on the 129Xe chemical shift. The results of these three experiments indicate that Xe transports through the gramicidin A channel.
authors.affiliation: Department of Chemistry/Biochemistry, University of Arkansas, Fayetteville 72701.
authors.forename: S
authors.initials: S
authors.lastname: McKim
authors.forename: J F
authors.initials: JF
authors.lastname: Hinton
mesh_terms: D000073738:2-Hydroxypropyl-beta-cyclodextrin; D001692:Biological Transport; D003505:Cyclodextrins; D006096:Gramicidin / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D014978:Xenon / Q000737:chemistry*; D014979:Xenon Isotopes; D047392:beta-Cyclodextrins
chemical_list: D003505:Cyclodextrins; D008051:Lipid Bilayers; D014979:Xenon Isotopes; D047392:beta-Cyclodextrins; D006096:Gramicidin; D000073738:2-Hydroxypropyl-beta-cyclodextrin; D014978:Xenon