Pathogenicity of Candida albicans: quest for a molecular switch.
Candida albicans is an opportunistic pathogen of human beings and other mammals. Two other features, besides its pathogenicity, have made it a popular organism for study. It exists in different cellular forms and can change from one form to another, depending on growth conditions. Thus, it is being used as a model system to study cellular differentiation. It can also heritably and reversibly switch its cellular and colony morphologies.
Datta
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Molecular Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
D000617:Aminoglycosides / Q000378:metabolism; D002118:Calcium / Q000502:physiology; D002176:Candida albicans / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D002177:Candidiasis / Q000209:etiology; D000242:Cyclic AMP / Q000502:physiology; D006801:Humans; D009024:Morphogenesis; D014774:Virulence
D000617:Aminoglycosides; D000242:Cyclic AMP; D002118:Calcium