Somite differentiation. Sonic signals somites.
Sonic hedgehog, a secreted signalling molecule known to play a role in the patterning of the central nervous system and the limb in vertebrates, also controls differentiation of the somites.
Bumcrot
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Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
McMahon
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AP
D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D004627:Embryonic Induction / Q000502:physiology*; D005314:Embryonic and Fetal Development / Q000502:physiology; D053823:Hedgehog Proteins; D018398:Homeodomain Proteins / Q000502:physiology; D008648:Mesoderm / Q000166:cytology / Q000502:physiology*; D051379:Mice; D009024:Morphogenesis / Q000502:physiology*; D009672:Notochord / Q000502:physiology / Q000637:transplantation; D011506:Proteins / Q000502:physiology*; D015534:Trans-Activators; D014157:Transcription Factors / Q000502:physiology; D014714:Vertebrates / Q000196:embryology*
D053823:Hedgehog Proteins; D018398:Homeodomain Proteins; D011506:Proteins; D015534:Trans-Activators; D014157:Transcription Factors