Silicone rubber-hydrogel composites as polymeric biomaterials. VI. Transport properties in the water-swollen state.
Permeation of inorganic salts in water-swollen silicone rubber-hydrogel composites consisting of a silicone rubber matrix and lightly cross-linked particles of poly(2-hydroxyethyl methacrylate), poly(2-hydroxyethyl methacrylate-co-methacrylic acid), poly(methacrylic acid), polyacrylamide or poly(acrylamide-co-methacrylic acid) hydrogels was investigated. The results, together with earlier data on permeation of non-ionic low-molecular-weight substances through the composite materials, were evaluated in terms of the free-volume diffusion theory. It was found that the materials with water content exceeding a certain limit are highly permeable to the salts, and that, as regards permeation properties, they behave as homogeneous water-swollen hydrogels. The dependence of electrical conductivity of the water-swollen composites on the hydrogel phase content was measured, and the results are discussed in relation to other transport properties and to the structure of the materials.
Lopour
P
P
Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Prague.
Janatová
V
V
D000180:Acrylic Resins / Q000737:chemistry / Q000378:metabolism; D001672:Biocompatible Materials / Q000592:standards*; D003188:Composite Resins / Q000737:chemistry* / Q000378:metabolism; D003432:Cross-Linking Reagents; D004058:Diffusion; D004553:Electric Conductivity; D005782:Gels; D008433:Mathematics; D008768:Methylmethacrylates / Q000737:chemistry / Q000378:metabolism; D008970:Molecular Weight; D011102:Polyhydroxyethyl Methacrylate / Q000737:chemistry / Q000378:metabolism; D011108:Polymers; D011109:Polymethacrylic Acids / Q000737:chemistry / Q000378:metabolism; D019736:Prostheses and Implants; D012826:Silicone Elastomers / Q000737:chemistry / Q000378:metabolism*
D000180:Acrylic Resins; D001672:Biocompatible Materials; D003188:Composite Resins; D003432:Cross-Linking Reagents; D005782:Gels; D008768:Methylmethacrylates; D011108:Polymers; D011109:Polymethacrylic Acids; D012826:Silicone Elastomers; C016680:polyacrylamide gels; C030613:polymethacrylic acid; D011102:Polyhydroxyethyl Methacrylate; C040206:HTR composite