title: Clausenol and clausenine--two carbazole alkaloids from Clausena anisata.
abstract: Two new carbazole alkaloids, designated as clausenol and clausenine, were isolated from an alcoholic extract of the stem bark of Clausena anisata. Their structures were established as 1-hydroxy-6-methoxy-3-methylcarbazole and 1,6-dimethoxy-3-methyl carbazole, respectively, from physical and chemical evidence and synthesis. Clausenol was found to be active against Gram-positive and Gram-negative bacteria and fungi.
authors.affiliation: Department of Chemistry, School of Tropical Medicine, Calcutta, India.
authors.forename: A
authors.initials: A
authors.lastname: Chakraborty
authors.forename: B K
authors.initials: BK
authors.lastname: Chowdhury
authors.forename: P
authors.initials: P
authors.lastname: Bhattacharyya
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002227:Carbazoles / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D018547:Plant Stems; D010946:Plants, Medicinal; D013055:Spectrophotometry, Infrared
chemical_list: D000900:Anti-Bacterial Agents; D002227:Carbazoles; C096080:clausenine; C096079:clausenol