title: Six year neurodevelopmental follow-up of very low birthweight children.
abstract: Twenty-four children born preterm with very low birthweight (VLBW) in 1985 at Bikur Holim Hospital were followed until age 6 years. Their neurological status and developmental and cognitive abilities were examined at 1, 2 and 6 years of age respectively and were compared with a control group at age 6 years. Of the 24 VLBW children, 4 had major disabilities. Of those without major disabilities, mean total IQ (WPPSI) at six years was 101.5 +/- 11.3, not significantly different from their mean Mental Development Index (Bayley) at age 2 years which was 96.1 +/- 19.6, or from the mean total IQ of a control group of 6-year-old children which was 109.8 +/- 14.7. However, the mean verbal IQ of the VLBW children (95.3 +/- 11.7) was significantly lower than that of the control group (106.2 +/- 14.3) (P = 0.02). Minor neurological deficit was found in seven of the VLBW children and in only one of the controls (P = 0.05). These findings point to possible future learning difficulties and should alert both pediatricians and educationalists to the importance of long-term follow-up of VLBW children in order to identify and address their specific educational needs.
authors.affiliation: Department of Neonatology, Bikur Holim Hospital, Jerusalem, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Litt
authors.forename: A
authors.initials: A
authors.lastname: Joseph
authors.forename: R
authors.initials: R
authors.lastname: Gale
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000175:diagnosis / Q000209:etiology*; D006233:Persons with Disabilities; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007361:Intelligence Tests; D008297:Male; D009460:Neurologic Examination