title: Detection of deep myometrial invasion in endometrial carcinoma: comparison of transvaginal ultrasound, CT, and MRI.
abstract: OBJECTIVE
  The aim of this study was to compare the accuracy of transvaginal US (TVUS), CT, and MRI in detecting deep myometrial invasion in endometrial carcinoma.
  
  
  METHODS
  Twenty-six patients with endometrial carcinoma were evaluated with TVUS, CT, and MRI. The depth of myometrial invasion was estimated in each examination. The invasion depth was categorized into no/superficial and deep and was compared to surgical and pathologic findings.
  
  
  RESULTS
  At pathologic examination, the depth of myometrial invasion was no/superficial in 16 patients and deep in 10. The accuracy/sensitivity/specificity of TVUS, CT, and MRI in detecting deep myometrial invasion were 69/50/81, 61/40/75, and 89%/90%/88%, respectively. The sensitivity and accuracy of MRI in detecting deep myometrial invasion were significantly higher than those of TVUS and CT (p = 0.049 for both sensitivity and accuracy).
  
  
  CONCLUSIONS
  We recommend MRI instead of CT or TVUS for the evaluation of the depth of myometrial invasion in endometrial carcinoma.
authors.affiliation: Department of Diagnostic Radiology, Seoul National University College of Medicine, Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.forename: H D
authors.initials: HD
authors.lastname: Kim
authors.forename: Y S
authors.initials: YS
authors.lastname: Song
authors.forename: S B
authors.initials: SB
authors.lastname: Kang
authors.forename: H P
authors.initials: HP
authors.lastname: Lee
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology; D018196:Carcinoma, Adenosquamous / Q000000981:diagnostic imaging / Q000473:pathology; D003287:Contrast Media; D004107:Dilatation and Curettage; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009215:Myometrium / Q000000981:diagnostic imaging* / Q000473:pathology*; D009361:Neoplasm Invasiveness; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000473:pathology
chemical_list: D003287:Contrast Media