title: Posterior spinal arthrodesis for atlantoaxial instability in Down syndrome.
abstract: Nine children with Down syndrome who had atlantoaxial instability underwent posterior spinal fusion. At follow-up, all patients had stabilization or improvement of their neurologic symptoms. Evaluation of the spine using flexion and lateral radiographs, as well as selective cineradiography, showed no instability over the fused area or adjacent motion segments. Stable fibrous union with no clinical significance was noted in three of the nine patients. We recommend posterior spinal fusion in situ with external immobilization as the safest and most effective means of surgical stabilization in the patient with Down syndrome who has symptomatic atlantoaxial instability.
authors.affiliation: Alfred I. duPont Institute, Wilmington, Delaware 19899, USA.
authors.forename: S
authors.initials: S
authors.lastname: Rizzolo
authors.forename: M J
authors.initials: MJ
authors.lastname: Lemos
authors.forename: D E
authors.initials: DE
authors.lastname: Mason
mesh_terms: D000293:Adolescent; D000328:Adult; D001268:Atlanto-Axial Joint / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007593:Joint Instability / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D011859:Radiography; D013123:Spinal Fusion / Q000379:methods*; D016896:Treatment Outcome