Recognition system for dietary fatty acids in the rat small intestine.
Linoleic acid and oleic acid markedly increased the influx of 45Ca into isolated intestinal epithelial cells, and this increase reflected a rise in the intracellular calcium level. Methyl linoleate had no effect, while glutamic acid and somatostatin both inhibited the linoleic acid-induced influx of 45Ca. In addition, methyl linoleate had no effect, while glutamic acid inhibited linoleic acid-induced hormone-responsive pancreatic exocrine secretion.
Shintani
T
T
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.
Takahashi
N
N
Fushiki
T
T
Kotera
J
J
Sugimoto
E
E
D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D002478:Cells, Cultured; D004041:Dietary Fats / Q000494:pharmacology*; D005768:Gastrointestinal Hormones / Q000378:metabolism; D018698:Glutamic Acid / Q000494:pharmacology; D007413:Intestinal Mucosa / Q000166:cytology; D007421:Intestine, Small / Q000166:cytology / Q000378:metabolism*; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000494:pharmacology; D019301:Oleic Acid; D009829:Oleic Acids / Q000494:pharmacology; D010179:Pancreas / Q000378:metabolism; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism
D004041:Dietary Fats; D005768:Gastrointestinal Hormones; D008041:Linoleic Acids; D009829:Oleic Acids; D016194:Receptors, N-Methyl-D-Aspartate; C005575:methyl linoleate; D019301:Oleic Acid; D001224:Aspartic Acid; D018698:Glutamic Acid; D019787:Linoleic Acid; D002118:Calcium