[Preliminary observation on the destructive effect of chemical disinfectants in serum markers of hepatitis B and C].
Chloroform, 40% formaldehyde, 3% hydrogen peroxide solution and 75% alcohol were used to act on hepatitis B surface antigen (HBeAg), hepatitis B e antigen (HBaAg) and anti-hepatitis C virus antibody (Anti-HCV) positive serum for 5, 15, 30 and over 60 minutes. They were examined by enzyme-linked immunosorbent assay and observed for the effect. The destructive effect of chloroform on HBsAg and anti-HCV positive derum was marked. It was discovered that 40% formaldehyde solution destroyed HBsAg, HBeAg, and anti-HCV positive serm, while 75% alcohol also showed destructive effect on HBsAg, HBeAg and anti-HCV positive serum.
Yang
S M
SM
Blood bank, Tang Du Hospital, Fourth Military Medical University, Xian.
Yang
C L
CL
An
R M
RM
D002725:Chloroform / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D005557:Formaldehyde / Q000494:pharmacology; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000187:drug effects; D006514:Hepatitis B Surface Antigens / Q000187:drug effects*; D006513:Hepatitis B e Antigens / Q000187:drug effects*; D018937:Hepatitis C Antibodies; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology
D004202:Disinfectants; D006508:Hepatitis Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D018937:Hepatitis C Antibodies; D005557:Formaldehyde; D002725:Chloroform; D006861:Hydrogen Peroxide