Transferases of O-antigen biosynthesis in Salmonella enterica: dideoxyhexosyltransferases of groups B and C2 and acetyltransferase of group C2.
The O antigen is a polymer of oligosaccharide units. O antigens differ in their sugar composition and glycosidic linkages, and genes responsible for O-antigen-specific biosynthesis are grouped in the rfb gene cluster. In this study, we identified two abequosyltransferase genes and an acetyltransferase gene in Salmonella enterica groups B and C2 by in vitro assay and identified paratosyl-, tyvelosyl-, and abequosyltransferase genes from S. enterica groups A and D and Yersinia pseudotuberculosis serovar IIA, respectively, by comparison.
Liu
D
D
Department of Microbiology, University of Sydney, New South Wales, Australia.
Lindqvist
L
L
Reeves
P R
PR
D000123:Acetyltransferases / Q000302:isolation & purification / Q000378:metabolism; D000595:Amino Acid Sequence; D002240:Carbohydrate Sequence; D003837:Deoxy Sugars / Q000378:metabolism*; D006601:Hexoses / Q000378:metabolism*; D006602:Hexosyltransferases / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D008969:Molecular Sequence Data; D019081:O Antigens; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis*; D012475:Salmonella / Q000201:enzymology* / Q000235:genetics / Q000276:immunology; D017386:Sequence Homology, Amino Acid; D013379:Substrate Specificity
D003837:Deoxy Sugars; D006601:Hexoses; D019081:O Antigens; D011135:Polysaccharides, Bacterial; D000123:Acetyltransferases; D006602:Hexosyltransferases; C094585:abequosyltransferase