title: Effects of spo0 mutations on spo0A promoter switching at the initiation of sporulation in Bacillus subtilis.
abstract: Transcriptional analyses of the Bacillus subtilis sporulation initiator gene spo0A revealed that promoter switching from the vegetative (Pv) to the sporulation-specific (Ps) promoter did not occur in the spo0A, spo0B, spo0E, spo0F, and spo0H mutants. The sof-1 mutation in spo0A restored the promoter switching in the spo0F mutant. These results strongly suggest that Spo0A plays a central role in the regulation of its own promoter switching.
authors.affiliation: Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Chibazakura
authors.forename: F
authors.initials: F
authors.lastname: Kawamura
authors.forename: K
authors.initials: K
authors.lastname: Asai
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics* / Q000502:physiology; D001426:Bacterial Proteins / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D009154:Mutation; D011401:Promoter Regions, Genetic; D012329:RNA, Bacterial / Q000235:genetics; D013170:Spores / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic; D001616:beta-Galactosidase / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D012329:RNA, Bacterial; C080950:Spo0A protein, Bacillus subtilis; D014157:Transcription Factors; D001616:beta-Galactosidase