Simultaneous indocyanine green and fluorescein angiography.
OBJECTIVE
To facilitate the interpretation of the choroidal dye filling sequence, the use of simultaneous indocyanine green (ICG) and fluorescein angiography was evaluated.


METHODS
A single-wavelength scanning laser ophthalmoscope (SLO) was modified to a two-wavelength system, permitting the simultaneous recording of ICG and fluorescein angiography. This method has been used in 340 cases. About two thirds of the patients had well-defined or occult choroidal neovascularization (CNV) in age-related macular degeneration (AMD).


RESULTS
Simultaneous ICG and fluorescein angiography is feasible with a two-wavelength SLO and provides images of good quality. Two corresponding ICG and fluorescein angiography pictures can be presented as one combined red-green picture.


CONCLUSIONS
This method has three advantages: (1) it allows a precise comparison of the transit of both dyes through both circulations, and there are no differences in the injected bolus nor in the actual blood pressure; (2) the important features of the ICG angiograms are fully aligned with the critical retinal vascular landmarks provided by the fluorescein images; and (3) it is very time efficient--with a single injection and one photographic session, immediate results are obtained.
Bischoff
P M
PM
Department of Ophthalmology, Kantonsspital, St. Gallen, Switzerland.
Niederberger
H J
HJ
Török
B
B
Speiser
P
P
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply*; D019793:Fluorescein; D005451:Fluorescein Angiography; D005452:Fluoresceins; D005584:Fovea Centralis / Q000473:pathology; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D007834:Lasers; D008268:Macular Degeneration / Q000150:complications; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D019721:Ophthalmoscopes
D005452:Fluoresceins; D007208:Indocyanine Green; D019793:Fluorescein