[Effect of Astragalus membranaceus on T-lymphocyte subsets in patients with viral myocarditis].
The efficacy of Astragalus membranaceus (AM) oral liquor combined with routine therapy and routine therapy alone on T-lymphocyte subsets of peripheral blood in viral myocarditis patients have been studied. The results showed that the T-lymphocyte subsets profile and OKT4/OKT8 ratio of peripheral blood were significantly lower in viral myocarditis patients than that in healthy control (P < 0.05, 0.01). Routine therapy combined with AM could significantly enhance OKT3, OKT4 and OKT4/OKT8 ratio in the above-mentioned patients (P < 0.05, 0.01). The possible pharmacodynamic mechanism of improved cell immunity in viral myocarditis patients by combining routine therapy with AM was discussed.
Huang
Z Q
ZQ
Zhejiang provincial TCM Hospital, Hangzhou.
Qin
N P
NP
Ye
W
W
D000293:Adolescent; D000328:Adult; D027885:Astragalus propinquus; D016516:CD4-CD8 Ratio; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014777:Virus Diseases / Q000188:drug therapy* / Q000276:immunology
D004365:Drugs, Chinese Herbal