title: Segmental pruritus and intramedullary vascular malformation.
abstract: Pruritus remains a medical mystery. Generally related with dermatological diseases, it is rarely associated with a neurological cause. We report a case of segmental pruritus (right T2 dermatome) related to an intramedullary vascular malformation. An anatomicophysiological explanation is presented. It is the first demonstration in man that pain receptors are not involved in pruritus, and suggests pruritus is under the control of descending inhibitory pathways.
authors.affiliation: Department of Neurology, Centre hospitalier universitaire vaudois, Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Vuadens
authors.forename: F
authors.initials: F
authors.lastname: Regli
authors.forename: M
authors.initials: M
authors.lastname: Dolivo
authors.forename: A
authors.initials: A
authors.lastname: Uske
mesh_terms: D000368:Aged; D001132:Arm / Q000294:innervation; D001165:Arteriovenous Malformations / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009433:Neural Inhibition / Q000502:physiology; D011537:Pruritus / Q000209:etiology* / Q000503:physiopathology; D012867:Skin / Q000294:innervation; D013116:Spinal Cord / Q000098:blood supply*; D013595:Syringomyelia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology