Detection of a C-insertion polymorphism within the human tumor necrosis factor alpha (TNFA) gene.
We have identified a C-insertion polymorphism in the 5'UTR of the first exon of the human tumor necrosis factor alpha (TNFA) gene. TNFA is a cytokine that plays an important role in the inflammatory response.
Brinkman
B M
BM
Department of Rheumatology, University Hospital Leiden, The Netherlands.
Kaijzel
E L
EL
Huizinga
T W
TW
Giphart
M J
MJ
Breedveld
F C
FC
Verweij
C L
CL
D001483:Base Sequence; D002896:Chromosomes, Human, Pair 6; D004251:DNA Transposable Elements / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
D004251:DNA Transposable Elements; D014409:Tumor Necrosis Factor-alpha