title: Adenovirus-mediated gene transfer for cystic fibrosis: Part A. Safety of dose and repeat administration in the nasal epithelium. Part B. Clinical efficacy in the maxillary sinus.
authors.affiliation: Howard Hughes Medical Institute, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Welsh
authors.forename: J
authors.initials: J
authors.lastname: Zabner
authors.forename: S M
authors.initials: SM
authors.lastname: Graham
authors.forename: A E
authors.initials: AE
authors.lastname: Smith
authors.forename: R
authors.initials: R
authors.lastname: Moscicki
authors.forename: S
authors.initials: S
authors.lastname: Wadsworth
mesh_terms: D000260:Adenoviruses, Human / Q000235:genetics*; D002985:Clinical Protocols; D002986:Clinical Trials as Topic; D003550:Cystic Fibrosis / Q000628:therapy*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005260:Female; D018014:Gene Transfer Techniques / Q000009:adverse effects; D015316:Genetic Therapy / Q000009:adverse effects; D005822:Genetic Vectors / Q000235:genetics; D006801:Humans; D008297:Male; D008443:Maxillary Sinus; D008565:Membrane Proteins / Q000008:administration & dosage / Q000235:genetics* / Q000627:therapeutic use; D009297:Nasal Mucosa
chemical_list: C505032:CFTR protein, human; D008565:Membrane Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator