A collapsing form of glomerulopathy.
An unusual presentation of glomerular disease occurring in a 30 year old black female is described. The case was characterized by a rapid deterioration of renal function. Associated glomerular manifestations were diffuse collapse of the glomerular capillary lumina, extracapillary hypercellularity without obliteration of the urinary space and without proliferation of parietal epithelial cells, electron-dense deposits, and deposition of IgG and C3. There was little loss of tubules and minor interstitial fibrosis. This case demonstrated a collapsing form of glomerulopathy with immunoglobulin and electron-dense deposits.
Shimamura
T
T
Department of Pathology, University of Medicine and Dentistry of NJ, Robert Wood Johnson Medical School, Piscataway 08854, USA.
Walker
J
J
D000328:Adult; D003176:Complement C3 / Q000032:analysis; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007674:Kidney Diseases / Q000276:immunology / Q000473:pathology*; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure
D003176:Complement C3; D007074:Immunoglobulin G