Excretion from rats of ketone bodies and methylmalonic acid in urine resulting from dietary vitamin B12 deficiency.
Ketone bodies were assayed in the urine of ten-week-old vitamin B12-deficient rats by a high-performance liquid chromatography. The urinary excretion of ketone bodies (352.5 +/- 68.3 mumol/day) as well as of methylmalonic acid was increased significantly by dietary vitamin B12 deficiency.
Toyoshima
S
S
Department of Applied Biological Chemistry, University of Osaka Prefecture, Japan.
Watanabe
F
F
Saido
H
H
Miyatake
K
K
Nakano
Y
Y
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D006879:Hydroxocobalamin / Q000378:metabolism; D007657:Ketone Bodies / Q000652:urine*; D008297:Male; D008764:Methylmalonic Acid / Q000652:urine*; D051381:Rats; D017208:Rats, Wistar; D014806:Vitamin B 12 Deficiency / Q000652:urine*; D015430:Weight Gain
D007657:Ketone Bodies; D008764:Methylmalonic Acid; D006879:Hydroxocobalamin