Tropheryma whippelii endocarditis confirmed by polymerase chain reaction.
This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causative organism in infective endocarditis.
Wendler
D
D
Department of Pathology, General Hospital of Ludwigshafen/Rhein, Germany.
Mendoza
E
E
Schleiffer
T
T
Zander
M
M
Maier
M
M
D039903:Actinobacteria / Q000302:isolation & purification*; D000328:Adult; D001021:Aortic Valve / Q000382:microbiology; D004697:Endocarditis, Bacterial / Q000175:diagnosis*; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D012329:RNA, Bacterial / Q000302:isolation & purification; D008061:Whipple Disease / Q000175:diagnosis*
D012329:RNA, Bacterial