title: Prediction of complications following caustic ingestion in adults.
abstract: The records of 86 adults admitted to hospital following caustic ingestion were reviewed. Eighteen patients (21%) developed complications; of these, six were fatal. Patients without symptoms or signs did not develop complications. Complications occurred only following lye ingestion, or intentional ingestion of hydrochloric acid or ammonia water. Of patients with such ingestion, and two signs or symptoms or more, 70% developed complications. Oesophagoscopy did not significantly improve the prediction of complications. There was a strong trend, however, for more severe complications with more severe submucosal, circumferential oesophageal injuries (P = 0.003). The study suggests that only adults with symptoms or signs following strong alkali or strong acid ingestion are at risk of complications. In adults who are symptomatic following ingestion of strong acid or alkali, oesophagoscopy is important to identify the potentially fatal transmural injuries.
authors.affiliation: ENT Department, Kommunehospitalet Aarhus, University Hospital, Denmark.
authors.forename: H B
authors.initials: HB
authors.lastname: Christesen
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000641:Ammonia / Q000008:administration & dosage* / Q000009:adverse effects*; D004935:Esophageal Diseases / Q000209:etiology* / Q000503:physiopathology; D004945:Esophagoscopy; D004947:Esophagus / Q000293:injuries* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006851:Hydrochloric Acid / Q000008:administration & dosage* / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
chemical_list: D000641:Ammonia; D006851:Hydrochloric Acid