title: Preclinical testing of total hip stems. The effects of coating placement.
abstract: The long-term fixation endurance of noncemented hip stems in total hip arthroplasty is subject to incompatible design goals. To reduce stress shielding and periprosthetic bone loss, proximal fixation and load transfer are indicated. However, to prevent interface motion and promote interface-bonding security, fixation preferably should be maximized over the entire stem surface. In this study, the authors questioned whether hydroxyapatite coatings could be applied in patterns that reduce bone resorption, while maintaining safe interface stress levels. For that purpose, strain-adaptive bone-remodeling theory was applied in 3-dimensional finite element models, to simulate the long-term postoperative bone resorption process. During the process, the adaptation of interface stresses was monitored, and its effects on interface failure probability evaluated. This analysis was done for a fully coated stem, a 1/3 proximally coated stem, a smooth uncoated, press-fitted stem, and a stem with 5 proximal patches of circumferential stripes. The uncoated stem reduced bone loss dramatically, but promoted interface motions and distal pedestal formation. In all cases, the gradual bone-remodeling process increased the interface security of the coated stems. Bone loss and interface failure probability were not very different for the fully and 1/3-coated stems. Stripe coating reduced bone resorption considerably, while increasing long-term interface failure probability only slightly. The investigators concluded that the initial stability and the ingrowth potential of such a stem design are likely to be inadequate.
authors.affiliation: Orthopaedics Department, University of Nijmegen, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Huiskes
authors.forename: B
authors.initials: B
authors.lastname: van Rietbergen
mesh_terms: D015519:Bone Density; D016723:Bone Remodeling; D001862:Bone Resorption / Q000517:prevention & control; D005269:Femur; D006622:Hip Prosthesis; D006801:Humans; D006882:Hydroxyapatites; D008422:Materials Testing / Q000379:methods*; D008953:Models, Anatomic; D011474:Prosthesis Design; D013314:Stress, Mechanical
chemical_list: D006882:Hydroxyapatites