[A case of primary mediastinal germ cell tumor, successfully treated with chemotherapy and curative resection].
A 20-year-old man was admitted to our hospital because of an abnormal shadow on chest X-ray Laboratory data revealed a high serum alpha-fetoprotein (AFP) and LDH level. Percutaneous needle biopsy of the tumor suggested primary mediastinal germ cell tumor. Curative resection was performed after three courses of combination chemotherapy (cis-platinum, VP-16, bleomycin and adriamycin). A post-operative histological examination of the mass revealed total necrosis. Post-operative course was uneventful, and he has been free of recurrence for the last six months.
Tabuchi
A
A
Department of Thoracic Cardiovascular Surgery, Kawasaki Medical School, Kurashiki, Japan.
Katsumura
T
T
Fujiwara
T
T
Doko
S
S
Inada
H
H
Masaki
H
H
Yoshida
H
H
Fukuhiro
Y
Y
Ishida
A
A
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D018237:Germinoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000601:surgery*
D001761:Bleomycin; D005047:Etoposide; D004317:Doxorubicin; D002945:Cisplatin