The pseudocalanolides: structure revision of calanolides C and D.
Nmr spectra of synthetic structures corresponding to those initially reported for natural compounds calanolide C [1] and calanolide D [2] showed some subtle differences from those of the natural products. Further analysis has resulted in revision of the structures of the natural compounds, now renamed pseudocalanolides C [3] and D [4]. The absolute stereochemistry of pseudocalanolide C was established as [6S, 7S, 8R] using the modified Mosher's method.
McKee
T C
TC
Laboratory of Drug Discovery Research and Development, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
Cardellina
J H
JH
Dreyer
G B
GB
Boyd
M R
MR
D003374:Coumarins / Q000737:chemistry* / Q000494:pharmacology; D054303:HIV Reverse Transcriptase; D015497:HIV-1 / Q000201:enzymology*; D016350:Leucine Zippers; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry; D018894:Reverse Transcriptase Inhibitors
D003374:Coumarins; D018894:Reverse Transcriptase Inhibitors; C095618:pseudocalanolide C; C095619:pseudocalanolide D; D054303:HIV Reverse Transcriptase