The microscopic interaction between silicone and the surrounding tissues.
Biocompatibility is a pivotal issue in the use of any implantable biomaterial. This article describes some of the issues surrounding the use of silicone implants for first metatarsophalangeal joint prostheses. The focus is on the interactions between the implant and the surrounding tissues. Common histologic findings are also discussed.
Needelman
L
L
Heights Medical, Hasbrouck, New Jersey, USA.
D018786:Bone Substitutes / Q000009:adverse effects*; D005549:Foreign-Body Reaction / Q000276:immunology; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects*; D011475:Prosthesis Failure; D012826:Silicone Elastomers / Q000009:adverse effects*; D013583:Synovial Membrane / Q000473:pathology; D013585:Synovitis / Q000209:etiology
D018786:Bone Substitutes; D012826:Silicone Elastomers