Membrane thrombomodulin levels are decreased during hypoxia and restored by cAMP and IBMX.
Dufourcq
P
P
Laboratories of Hematology, INSERM U8, Pessac, France.
Seigneur
M
M
Pruvost
A
A
Dumain
P
P
Belloc
F
F
Amiral
J
J
Boisseau
M R
MR
D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology*; D015687:Cell Hypoxia; D002462:Cell Membrane / Q000187:drug effects; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology; D015536:Down-Regulation; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D008562:Membrane Glycoproteins / Q000378:metabolism*; D018180:Thrombomodulin / Q000378:metabolism*; D014471:Umbilical Veins; D015854:Up-Regulation / Q000187:drug effects
D008562:Membrane Glycoproteins; D018180:Thrombomodulin; D003513:Cycloheximide; D000242:Cyclic AMP; D015056:1-Methyl-3-isobutylxanthine