title: In vivo measurement of a diurnal variation in vasopressin release in the rat suprachiasmatic nucleus.
abstract: Diurnal changes in the intranuclear release of vasopressin (VP) and oxytocin (OT) in the suprachiasmatic (SCN), paraventricular (PVN) and supraoptic nuclei (SON) of the rat were studied by means of brain microdialysis. A significant diurnal variation in VP release in the SCN was detected, with the highest levels occurring during midday and a trough around midnight. OT release from the SCN was below detection limit. The release of neither of these neurohypophysial peptides showed diurnal variations within the PVN or SON.
authors.affiliation: Max-Planck Institute of Psychiatry, Clinical Institute, Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Kalsbeek
authors.forename: R M
authors.initials: RM
authors.lastname: Buijs
authors.forename: M
authors.initials: M
authors.lastname: Engelmann
authors.forename: C T
authors.initials: CT
authors.lastname: Wotjak
authors.forename: R
authors.initials: R
authors.lastname: Landgraf
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D005612:Freeze Drying; D007457:Iodine Radioisotopes; D008297:Male; D017551:Microdialysis; D010121:Oxytocin / Q000378:metabolism; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013493:Suprachiasmatic Nucleus / Q000378:metabolism*; D013495:Supraoptic Nucleus / Q000378:metabolism; D014667:Vasopressins / Q000378:metabolism*
chemical_list: D007457:Iodine Radioisotopes; D014667:Vasopressins; D010121:Oxytocin