[Use of a turbidimetric method to study the kinetics of inhibition of fibrinolysis in diluted blood plasma].
Dependence of fibrinolysis parameters on the concentration of inhibitors of fibrinolytic process has been studied when using turbidimetric method. It is shown that the process of destruction of fibrin clot formed in diluted blood plasma is subjected to the Michaelis-Menten ratio. The constant of inhibition of fibrinolytic process in diluted plasma activated by prothrombin and streptokinase is 10 and 0.5 microM for 6-aminohexanoic acid and contrykal, respectively.
Sokolovskaia
L I
LI
Lezhen
T I
TI
Makogonenko
E M
EM
D015119:Aminocaproic Acid / Q000494:pharmacology*; D007611:Aprotinin / Q000494:pharmacology*; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D007700:Kinetics; D009391:Nephelometry and Turbidimetry; D011516:Prothrombin / Q000187:drug effects; D013300:Streptokinase / Q000187:drug effects
D011516:Prothrombin; D007611:Aprotinin; D013300:Streptokinase; D015119:Aminocaproic Acid