title: Production of granulocyte colony-stimulating factor by malignant mesothelioma.
abstract: We present the case of a male patient, aged 45 yrs, with malignant mesothelioma producing granulocyte colony-stimulating factor (G-CSF). The diagnosis was established by histopathological examination of the autopsied pleural tissues. Production of G-CSF was confirmed by immunoperoxidase staining, using a specific monoclonal antibody against recombinant G-CSF (rhG-CSF).
authors.affiliation: Dept of Medicine, University School of Medicine, Kurume, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Rikimaru
authors.forename: Y
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ogawa
authors.forename: E
authors.initials: E
authors.lastname: Higuchi
authors.forename: M
authors.initials: M
authors.lastname: Kinosita
authors.forename: K
authors.initials: K
authors.lastname: Oizumi
authors.forename: I
authors.initials: I
authors.lastname: Shima
mesh_terms: D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000378:metabolism*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000378:metabolism*
chemical_list: D016179:Granulocyte Colony-Stimulating Factor