Ail expression in Yersinia enterocolitica is affected by oxygen tension.
We investigated several environmental factors for their abilities to regulate ail gene expression and found that ail transcript levels are regulated by oxygen tension. Bacteria growing under anaerobiosis at 37 degrees C repress ail mRNA and Ail expression, resulting in a loss of Ail-mediated serum resistance and cell invasion.
Pederson
K J
KJ
Department of Microbiology, University of Colorado Health Sciences Center, Denver 80262, USA.
Pierson
D E
DE
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D001770:Blood Bactericidal Activity; D016466:CHO Cells; D006224:Cricetinae; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D008969:Molecular Sequence Data; D010100:Oxygen; D015008:Yersinia enterocolitica / Q000235:genetics* / Q000276:immunology
C069712:Ail protein, Yersinia enterocolitica; D001425:Bacterial Outer Membrane Proteins; D010100:Oxygen