The C-32 triacetyl-L-rhamnose derivative of ascomycin: a potent, orally active macrolactone immunosuppressant.
Koch
K
K
Central Research Division, Pfizer Inc., Groton, Connecticut 06340, USA.
Newborg
M F
MF
Hanson
D C
DC
Cooper
K
K
Shepard
R M
RM
Biehl
M L
ML
Biggers
M S
MS
Ramchandani
M
M
Schulte
G
G
Snyder
J R
JR
D000284:Administration, Oral; D000818:Animals; D002240:Carbohydrate Sequence; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology; D007783:Lactones / Q000737:chemistry*; D008969:Molecular Sequence Data; D051381:Rats; D012210:Rhamnose / Q000737:chemistry*; D016559:Tacrolimus / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology
D007166:Immunosuppressive Agents; D007783:Lactones; C058028:immunomycin; D012210:Rhamnose; D016559:Tacrolimus