title: Drug therapy of peptic ulcer disease.
abstract: Healing of peptic ulcers can be achieved by using a variety of anti-ulcer medications. The most commonly used agents include the histamine-2 receptor antagonists (H2RAs) and the proton pump inhibitors. They are also efficacious in preventing ulcer recurrence providing maintenance treatment is given. The ideal treatment for peptic ulcers today is aiming at eradication of Helicobacter pylori infection. Successful elimination of the latter not only heals the ulcers but also provides a cure for the disease, so that the patients will no longer require lifelong maintenance medical therapy.
authors.affiliation: University Department of Medicine, Queen Mary Hospital, Hong Kong.
authors.forename: C K
authors.initials: CK
authors.lastname: Ching
authors.forename: S K
authors.initials: SK
authors.lastname: Lam
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D015738:Famotidine / Q000627:therapeutic use*; D005764:Gastroesophageal Reflux / Q000188:drug therapy; D016480:Helicobacter pylori / Q000302:isolation & purification; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D064747:Lansoprazole; D009853:Omeprazole / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D010437:Peptic Ulcer / Q000188:drug therapy* / Q000382:microbiology; D011899:Ranitidine / Q000627:therapeutic use*; D015043:Zollinger-Ellison Syndrome / Q000188:drug therapy
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000897:Anti-Ulcer Agents; D018680:Cholinergic Antagonists; D006635:Histamine H2 Antagonists; D064747:Lansoprazole; D015738:Famotidine; D011899:Ranitidine; D009853:Omeprazole