title: Neonatal pulmonary vascular disease in hypoplastic left heart syndrome.
abstract: A term neonate with hypoplastic left heart syndrome underwent surgical palliation using the Norwood procedure on day 2 of life. The postoperative course was complicated by recurrent systemic desaturation leading to death. Postmortem histologic examination of lung tissue confirmed the clinical impression of fixed pulmonary vascular disease. Some neonates with a restrictive interatrial communication may have pulmonary vascular disease at birth, which will negatively influence survival irrespective of the type of palliation undertaken.
authors.affiliation: Heart Unit, Birmingham Children's Hospital, England.
authors.forename: S
authors.initials: S
authors.lastname: Brann
authors.forename: W J
authors.initials: WJ
authors.lastname: Brawn
authors.forename: F
authors.initials: F
authors.lastname: Raafat
authors.forename: N
authors.initials: N
authors.lastname: Sreeram
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000150:complications* / Q000601:surgery; D007231:Infant, Newborn; D008297:Male; D010166:Palliative Care; D011651:Pulmonary Artery / Q000473:pathology; D011668:Pulmonary Veno-Occlusive Disease / Q000150:complications* / Q000473:pathology