title: Antiperoxide effects of S-allyl cysteine sulphoxide isolated from Allium sativum Linn and gugulipid in cholesterol diet fed rats.
abstract: Cholesterol containing diet significantly increased not only the body weight, but also the weight of liver and adipose tissue of rats. This is accompanied by a significant increase in blood lipids, atherogenic index and lipid peroxidation and a significant decrease in reduced glutathione level, superoxide dismutase and catalase activities in tissues. Treatment with S-allyl cysteine sulphoxide reverses the deleterious effects of cholesterol diet significantly and almost as effectively as gugulipid.
authors.affiliation: Department of Biochemistry, University of Kerala, India.
authors.forename: C G
authors.initials: CG
authors.lastname: Sheela
authors.forename: K T
authors.initials: KT
authors.lastname: Augusti
mesh_terms: D000490:Allium / Q000737:chemistry*; D000818:Animals; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D029744:Commiphora; D003545:Cysteine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D053149:Plant Gums; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D002791:Cholesterol, Dietary; D000960:Hypolipidemic Agents; D010936:Plant Extracts; D053149:Plant Gums; C018562:guggulu extract; C006453:alliin; D003545:Cysteine