Intrapleural mitoxantrone for the palliative treatment of malignant pleural effusions.
A group of 21 patients with malignant pleural effusions were treated with the instillation of 40 mg mitoxantrone intrapleurally, after complete fluid drainage. There was a 100% complete response rate with no toxic effects (0%). The mean survival of the patients was 57.1 weeks.
Morales
M
M
Department of Medicine, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain.
Expósito
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MC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D008297:Male; D008875:Middle Aged; D008942:Mitoxantrone / Q000008:administration & dosage*; D010166:Palliative Care; D016066:Pleural Effusion, Malignant / Q000188:drug therapy*; D016896:Treatment Outcome
D008942:Mitoxantrone