title: Toxigenicity of culture filtrates of Salmonella enteritidis isolates on three mammalian cell lines.
abstract: Culture filtrates of 28 Salmonella enteritidis isolates were tested for toxicity on Vero-, CHO-, and human foreskin fibroblast (HFF) cells. Cytopathic effects on HFF cells were extensive, and were observed even with some filtrates diluted 1:256. Vero cells showed effects with filtrates diluted up to 1:16, and CHO cells gave weak or no reaction. All isolates produced iron-binding siderophores as determined by reactions on chrome-azurol-S medium.
authors.affiliation: Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Hariharan
authors.forename: S B
authors.initials: SB
authors.lastname: Heaney
authors.forename: J T
authors.initials: JT
authors.lastname: Singer
mesh_terms: D000818:Animals; D016466:CHO Cells; D016923:Cell Death; D002460:Cell Line; D002522:Chlorocebus aethiops; D006224:Cricetinae; D003603:Cytotoxins / Q000032:analysis*; D006801:Humans; D012477:Salmonella enteritidis / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D017262:Siderophores / Q000096:biosynthesis; D014709:Vero Cells
chemical_list: D003603:Cytotoxins; D017262:Siderophores