title: Distribution of galanin-immunoreactive nerves in the canine gastrointestinal tract.
abstract: The distribution of nerves containing galanin immunoreactivity (GAL-IR) in the canine gastrointestinal tract was determined by immunohistochemistry. GAL-IR was observed in nerve cell bodies and nerve fibers in all layers of the lower esophagus, gastric antrum, pylorus, ileum, and colon, and in the sphincters of lower esophagus and pylorus. There were numerous GAL-IR-containing nerve cell bodies in the myenteric plexus of gastric antrum. GAL-IR nerve somata were also common in the myenteric plexus of lower esophagus, ileum, pylorus, and colon, and in the submucous plexus of stomach, ileum, and colon. GAL-IR-positive nerve fibers were also observed around submucous blood vessels of the stomach. GAL-IR nerves are distributed more widely in the canine enteric nervous system than previously recognized.
authors.affiliation: Division of Physiology and Pharmacology, McMaster University, Hamilton, Canada.
authors.forename: Y F
authors.initials: YF
authors.lastname: Wang
authors.forename: Y K
authors.initials: YK
authors.lastname: Mao
authors.forename: T J
authors.initials: TJ
authors.lastname: McDonald
authors.forename: E E
authors.initials: EE
authors.lastname: Daniel
mesh_terms: D000818:Animals; D003106:Colon / Q000294:innervation; D004064:Digestive System / Q000294:innervation*; D004285:Dogs; D004947:Esophagus / Q000294:innervation; D005260:Female; D019004:Galanin; D005725:Ganglia, Autonomic / Q000166:cytology; D007082:Ileum / Q000294:innervation; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D009130:Muscle, Smooth / Q000294:innervation*; D009197:Myenteric Plexus / Q000166:cytology*; D009479:Neuropeptides / Q000032:analysis; D009928:Organ Specificity; D010455:Peptides / Q000032:analysis*; D013270:Stomach / Q000294:innervation
chemical_list: D009479:Neuropeptides; D010455:Peptides; D019004:Galanin