title: [Component analysis of variability as a method of differentiating simple effect from hazardous effect in toxicological experiments].
abstract: The article forms the main requirements for every hazard criterion (valid, definite, statistically correct, differential, invariable, sensitive, integral). The suggested hazard criterion is based on additive components of general dispersion. Those components reflect environmental influence (environmental effect) and influence of substance (effect of substance), then the components are compared according to Fisher criterion (F). The criterion works in two-factor dispersion analysis.
authors.forename: A F
authors.initials: AF
authors.lastname: Kovalev
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D004777:Environment; D006801:Humans; D008033:Limulus Test; D015233:Models, Statistical; D008962:Models, Theoretical; D012044:Regression Analysis; D014116:Toxicology / Q000379:methods*