Odontogenic keratocysts: a study of 50 patients.
The odontogenic keratocyst (OKC) is a locally aggressive neoplasm with rates of recurrence reported as high as 60%. Correlation between histopathology and the likelihood of recurrence remains a subject of controversy. In this review of the authors' experience in treating 50 patients with OKC between 1977 and 1993, 58 specimens were studied to correlate the likelihood of recurrence with the presence of the following histologic features--parakeratosis, orthokeratosis, satellite cysts, epithelial rests, or epithelial proliferation. Orthokeratinized cysts were associated with a higher recurrence rate than in previously reported studies. Disruption of the epithelial lining in the resected specimen was found to be a primary determinant of recurrence.
Anand
V K
VK
Department of Surgery, University of Mississippi Medical Center, Jackson 39126-4505.
Arrowood
J P
JP
Krolls
S O
SO
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002455:Cell Division; D002648:Child; D004848:Epithelium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation; D007633:Keratins; D007642:Keratosis / Q000473:pathology; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008439:Maxillary Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D012008:Recurrence
D007633:Keratins