Drug sensitivity ("suicide") genes for selective cancer chemotherapy.
Moolten
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FL
Edith Nourse Rogers Memorial Veterans Hospital, Bedford, Massachusetts 01730, USA.
D000212:Acyclovir / Q000493:pharmacokinetics / Q000627:therapeutic use; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001711:Biotransformation / Q000235:genetics*; D043525:Cytosine Deaminase; D004351:Drug Resistance / Q000235:genetics*; D029968:Escherichia coli Proteins; D015774:Ganciclovir / Q000493:pharmacokinetics / Q000627:therapeutic use; D005786:Gene Expression Regulation; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000235:genetics; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009369:Neoplasms / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000517:prevention & control; D009700:Nucleoside Deaminases / Q000235:genetics / Q000378:metabolism; D010430:Pentosyltransferases; D011230:Precancerous Conditions / Q000628:therapy; D011355:Prodrugs / Q000493:pharmacokinetics*; D011401:Promoter Regions, Genetic; D011506:Proteins; D011683:Purine-Nucleoside Phosphorylase / Q000235:genetics / Q000378:metabolism; D051381:Rats; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism / Q000627:therapeutic use*; D013937:Thymidine Kinase / Q000235:genetics / Q000378:metabolism; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D000509:alpha-Fetoproteins / Q000235:genetics
D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D011355:Prodrugs; D011506:Proteins; D011993:Recombinant Fusion Proteins; D014764:Viral Proteins; D000509:alpha-Fetoproteins; D010430:Pentosyltransferases; D011683:Purine-Nucleoside Phosphorylase; C071962:Gpt protein, E coli; D013937:Thymidine Kinase; D009700:Nucleoside Deaminases; D043525:Cytosine Deaminase; D015774:Ganciclovir; D000212:Acyclovir