title: Influence of ethanol on the salsolinol excretion in healthy subjects.
abstract: This report describes the change of salsolinol (SAL) levels in the urine of healthy subjects after ethanol ingestion. A new rapid method for SAL extraction from urine sample and a GC-MS assay were used to study the urinary SAL excretion in a group of adult males (n = 14) and females (n = 13) with and without ingestion of ethanol. The results of this study show that the urinary SAL output of all subjects is significantly influenced by the intake of ethanol. A decrease in the SAL level was found in the urine of most of the volunteers (n = 17), whereas only eight subjects showed an increase in the SAL level after administration of ethanol.
authors.affiliation: Research Institute for Molecular Pharmacology, Berlin, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Haber
authors.forename: I
authors.initials: I
authors.lastname: Putscher
authors.forename: M
authors.initials: M
authors.lastname: Georgi
authors.forename: M F
authors.initials: MF
authors.lastname: Melzig
mesh_terms: D000328:Adult; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007546:Isoquinolines / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D012016:Reference Values
chemical_list: D007546:Isoquinolines; D000431:Ethanol; C036617:salsolinol