title: Urodynamic changes in benign prostatic hyperplasia patients treated by transurethral microwave thermotherapy.
abstract: Our study describes the results obtained in 44 patients with benign prostatic hyperplasia (BPH) who underwent transurethral microwave thermotherapy (TUMT) and their follow-up at 12 months. Prostatron, a prostatic TUMT device which comprised a microwave heat generator and a cooling system, was used at our centre. Forty-four out of the 60 patients given the treatment had a 12-month follow-up to be evaluated. The evaluation of subjective symptoms, according to the Boyarsky symptom score, demonstrated a significant rate of response (p < 0.0005). The analysis of pressure-flow recordings demonstrated a reduction of mean detrusor opening pressure (p < 0.0005), a reduction of detrusor pressure at maximum flow 12 months after treatment (p < 0.0005) and an improvement of mean values of maximum flow after treatment (p < 0.0005). This study shows that TUMT, though it cannot be considered an alternative to surgical or endoscopic therapy of BPH for severely obstructed patients, can produce improvement of both subjective and objective parameters of mild prostatic bladder outflow obstruction.
authors.affiliation: Dipartimento di Scienze Chirurgiche e Trapinati d'organo, Clinica Urologica Università di Cagliari, Ospedale Santissima Trinità, Cagliari, Italia.
authors.forename: D
authors.initials: D
authors.lastname: Porru
authors.forename: R M
authors.initials: RM
authors.lastname: Scarpa
authors.forename: A
authors.initials: A
authors.lastname: Delisa
authors.forename: E
authors.initials: E
authors.lastname: Usai
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use; D008875:Middle Aged; D011312:Pressure; D011470:Prostatic Hyperplasia / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D014521:Urethra; D001743:Urinary Bladder / Q000503:physiopathology; D014563:Urodynamics