title: Correlation between micturitional urethral pressure profile and pressure-flow criteria in bladder outlet obstruction.
abstract: OBJECTIVE
  We correlate micturitional urethral pressure profilometry with pressure-flow diagnoses of outlet obstruction.
  
  
  METHODS
  Urodynamic evaluation was done of 86 consecutive men with voiding symptoms. Obstruction criteria were a micturitional urethral pressure profile (MUPP) gradient greater than 5 cm. water, Schäfer's linear passive urethral resistance relation (PURR) greater than grade 1 and Abrams-Griffiths nomogram.
  
  
  RESULTS
  Interpretable results were completed in 99% of the patients undergoing MUPP and 60% undergoing pressure-flow studies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients correlated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff values (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% and positive predictive value 94%.
  
  
  CONCLUSIONS
  MUPP correlates well with and yields interpretable results more often than pressure-flow studies.
authors.affiliation: Urology Division, Brockton/West Roxbury Veterans Administration Medical Center, Boston, Massachusetts, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: DuBeau
authors.forename: M P
authors.initials: MP
authors.lastname: Sullivan
authors.forename: E
authors.initials: E
authors.lastname: Cravalho
authors.forename: N M
authors.initials: NM
authors.lastname: Resnick
authors.forename: S V
authors.initials: SV
authors.lastname: Yalla
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011470:Prostatic Hyperplasia / Q000150:complications / Q000503:physiopathology*; D012372:ROC Curve; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000503:physiopathology*; D014554:Urination / Q000502:physiology; D014563:Urodynamics / Q000502:physiology*