Captopril-induced acute pancreatitis.
OBJECTIVE
To increase awareness concerning abdominal pain associated with the use of captopril, which is a molecule frequently used in diabetic patients.


METHODS
One case of acute pancreatitis associated with captopril, confirmed by a reintroduction, is described in a type II diabetes patient.


CONCLUSIONS
Captopril and other angiotensin-converting enzyme inhibitors are very frequently prescribed in diabetic patients. Therefore, it is important to be aware of the possibility of pancreatitis linked to these molecules and to withdraw the treatment in case of severe unexplained abdominal pain.
Jeandidier
N
N
Endocrinology Department, HUS-Hôpital Central, Strasbourg, France.
Klewansky
M
M
Pinget
M
M
D015746:Abdominal Pain; D000208:Acute Disease; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002216:Captopril / Q000009:adverse effects*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D007004:Hypoglycemic Agents; D002216:Captopril