title: [Treatment of differentiated carcinoma of the thyroid and its limitations].
abstract: The Authors report their experience in the management of differentiated thyroid cancer (DTC) with extrathyroidal extension including nodal and distant metastases. Twelve patients were included in the review: 11 of them were previously and elsewhere considered not curable. On the contrary, integrated treatment (surgery, radioiodine and radiation therapy) allowed to control the disease in 10 patients with a survival ranging from 14 years to 29 months. Cytopathologic analysis, in the two patients who died, showed a differentiated thyroid cancer with anaplastic areas. Integrated treatment, therefore, represents the treatment of choice for advanced DTC only in total absence of anaplastic cells.
authors.affiliation: Divisione di Chirurgia d'Urgenza, Università Cattolica del Sacro Cuore, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Wiel Marin
authors.forename: I
authors.initials: I
authors.lastname: Carlucci
authors.forename: G
authors.initials: G
authors.lastname: Wiel Marin
authors.forename: M
authors.initials: M
authors.lastname: Massari
authors.forename: A
authors.initials: A
authors.lastname: Romagnoli
mesh_terms: D006801:Humans; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*