Zinc-containing innervation of the subicular region in the rat.
The subiculum is densely innervated by zinc-containing axonal terminals, but the cells of origin of those zinc-containing afferents have not previously been identified. In the present work the zinc-specific retrograde tracing method was employed to locate the zinc-containing neurons afferent to the subicular complex. Following microinfusions into the subicular region, the somata of zinc-containing neurons were found in the hippocampus, the pre- and para subiculum, retrosplenial, cingulate, and perirhinal cortices, and in the anterodorsal nucleus of the thalamus. The results show another component of the zinc-containing associational network that interconnects the cerebral cortex and amygdalohippocampal systems of the brain.
Long
Y
Y
Laboratory for Neurobiology, University of Texas at Dallas, Richardson 75080, USA.
Hardwick
A L
AL
Frederickson
C J
CJ
D000818:Animals; D001370:Axonal Transport; D002540:Cerebral Cortex / Q000737:chemistry; D007031:Hypothalamus / Q000737:chemistry / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000737:chemistry / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D016622:Silver Staining; D014018:Tissue Distribution; D015032:Zinc / Q000032:analysis*
D015032:Zinc