Calcifying aponeurotic fibroma: a report of three cases.
Calcifying (juvenile) aponeurotic fibroma (CAF) is a rare disease entity characterized by a tendency to develop in the palms and soles of children and young adults. It has definite histologic features of an ill-circumscribed fibroblastic proliferation, with foci of calcification and chondroid differentiation, as well as a recurring or locally aggressive growth pattern. The commonly accepted mode of treatment is wide excision of the tumor; extensive surgery is usually not necessary even for recurrences. Three cases are reported, all of when were female with the age ranging from 8 to 27 years. All lesions were in the hand or foot, and one of them was recurrent. Immunohistochemical study was performed and the literature reviewed.
Lu
F H
FH
Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.
Tzen
C Y
CY
Chen
B F
BF
Chang
P Y
PY
D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000473:pathology*; D002648:Child; D005260:Female; D005350:Fibroma / Q000473:pathology*; D006801:Humans