title: [Cervical intraepithelial neoplasia: Chlamydia trachomatis and other co-factors].
abstract: The incidence of Chlamydia trachomatis (Ct) in patients with diagnosis of Cervical Intraepithelial Neoplasia (CIN) was studied in one hundred eighty patients. The Chlamydiazyme test was performed in all of them. Endocervical samples were taken from 103 patients with CIN and 77 women who sought medical attention for different gynecological reasons (CG). Twenty three tests (12.8%) were positive; 15 of them had CIN (14.6%) and 8 were from the control group (10.4%). It was found a statistical significant difference between NIC III and early intercourse, NIC III and age, NIC and vaginal douches and, among NIC and number of pregnancies and deliveries. There was not a significant difference among Ct and early intercourse, number of sexual partners, pregnancies, deliveries, vaginal douches, oral contraceptives (OC), and vaginal discharge. No statistically significant differences were found between NIC and number of sexual partners, and OC and vaginal discharge. The low incidence of Ct in patients with CIN does not mean that Ct does not play a role in the origin and development of the cervical pathology.
authors.affiliation: Departamento de Obstetricia y Ginecología, Hospital Manuel Noriega Trigo, Instituto Venezolano de los Seguros Sociales (IVSS), Maracaibo, Venezuela.
authors.forename: J T
authors.initials: JT
authors.lastname: Núñez-Troconis
mesh_terms: D000328:Adult; D002690:Chlamydia Infections / Q000150:complications / Q000453:epidemiology*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D015994:Incidence; D011446:Prospective Studies; D002583:Uterine Cervical Neoplasms / Q000382:microbiology*; D002578:Uterine Cervical Dysplasia / Q000382:microbiology*