title: The RNP domain: a sequence-specific RNA-binding domain involved in processing and transport of RNA.
abstract: The RNP domain is found in a number of proteins involved in processing and transport of mRNA precursors. The crystal structure of a complex between the U1A spliceosomal protein and its cognate RNA hairpin at 1.92 A resolution reveals the molecular basis of sequence-specific RNA recognition by the RNP domain.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: C
authors.initials: C
authors.lastname: Oubridge
authors.forename: N
authors.initials: N
authors.lastname: Ito
authors.forename: J
authors.initials: J
authors.lastname: Avis
authors.forename: P
authors.initials: P
authors.lastname: Evans
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001692:Biological Transport; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D012313:RNA / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional; D016601:RNA-Binding Proteins / Q000737:chemistry*; D012261:Ribonucleoproteins / Q000737:chemistry*
chemical_list: D016601:RNA-Binding Proteins; D012261:Ribonucleoproteins; D012313:RNA