title: [A case of astrocytoma of corpus callosum presented diagnostic dyspraxia].
abstract: A case of astrocytoma whose first clinical presentation was diagnostic dyspraxia was reported. A 38-year-old right-handed male experienced funny motion of his left hand triggered by voluntary movement of his right hand. One day, he tried to insert a coin into the vending machine with his right hand, then the left hand was against the other. One month after that event, he experienced headache and vertigo. On admission, there were no abnormal findings on neurological examination. On neuropsychological examination, he was cooperative, well orientated and attentive, and there were no callosal disconnection symptoms. Frontal lobe function tests were slightly impaired. T1-weighted MRI demonstrated irregular mixed signal intensity mass lesion extending from the genu to the body of the corpus callosum and the cingulate gyrus. This lesion was slightly enhanced with Gd-DTPA. Biopsy was performed and histological diagnosis was fibrillary astrocytoma. After irradiation and chemotherapy, he was discharged from the hospital without evident neurological deficit. About 20 cases of diagnostic dyspraxia have been reported and almost all of them were caused by cerebro-vascular disease. This is the first case of brain tumor who presented diagnostic dyspraxia.
authors.affiliation: Department of Neurosurgery, Toda Chuo General Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Koshimizu
authors.forename: E
authors.initials: E
authors.lastname: Takeyama
authors.forename: E
authors.initials: E
authors.lastname: Takeyama
authors.forename: H
authors.initials: H
authors.lastname: Kizuki
authors.forename: H
authors.initials: H
authors.lastname: Tei
authors.forename: O
authors.initials: O
authors.lastname: Kubo
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000150:complications* / Q000175:diagnosis; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis; D003337:Corpus Callosum; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000209:etiology*; D014057:Tomography, X-Ray Computed