title: The 1993-94 Généthon human genetic linkage map.
abstract: In 1992, we described a second-generation genetic linkage map of the human genome. Using 1,267 new microsatellite markers, we now present a new genetic linkage map containing a total of 2,066 (AC)n short tandem repeats, 60% of which show a heterozygosity of over 0.7. Statistical linkage analysis based on the genotyping of eight large CEPH families placed these markers in the 23 linkage groups. The map includes 1,266 intervals and spans a total distance of 3690 centiMorgans (cM). A total of 1,041 markers could be ordered with odds ratios greater than 1000:1. About 56% of this map is at a distance of 1 cM or less from one of its markers.
authors.affiliation: Centre d'Etudes du Polymorphisme Humain, Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Gyapay
authors.forename: J
authors.initials: J
authors.lastname: Morissette
authors.forename: A
authors.initials: A
authors.lastname: Vignal
authors.forename: C
authors.initials: C
authors.lastname: Dib
authors.forename: C
authors.initials: C
authors.lastname: Fizames
authors.forename: P
authors.initials: P
authors.lastname: Millasseau
authors.forename: S
authors.initials: S
authors.lastname: Marc
authors.forename: G
authors.initials: G
authors.lastname: Bernardi
authors.forename: M
authors.initials: M
authors.lastname: Lathrop
authors.forename: J
authors.initials: J
authors.lastname: Weissenbach
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D017931:DNA Primers; D004276:DNA, Satellite / Q000235:genetics; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D005838:Genotype; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data
chemical_list: D017931:DNA Primers; D004276:DNA, Satellite; D005819:Genetic Markers