Mice transgenic for human CD46 and CD55 are protected from human complement attack.
Mulder
L C
LC
Istituto Ricerche Immunobiologiche Siena, Italy.
Mora
M
M
Ciccopiedi
E
E
Melli
C
C
Nuti
S
S
Marinucci
G
G
Bruzzone
P
P
Lazzeri
M
M
Lorenzini
R
R
Alfani
D
D
D000818:Animals; D015703:Antigens, CD / Q000096:biosynthesis* / Q000502:physiology; D018958:CD55 Antigens; D003001:Cloning, Molecular; D050577:Complement C3-C5 Convertases / Q000037:antagonists & inhibitors; D003169:Complement Inactivator Proteins / Q000096:biosynthesis* / Q000502:physiology; D003165:Complement System Proteins / Q000502:physiology*; D018076:DNA, Complementary / Q000302:isolation & purification; D005260:Female; D015870:Gene Expression; D015723:Gene Library; D006801:Humans; D008099:Liver / Q000378:metabolism; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins / Q000096:biosynthesis* / Q000502:physiology; D051379:Mice; D008822:Mice, Transgenic; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000378:metabolism
D015703:Antigens, CD; C497857:CD46 protein, human; D018958:CD55 Antigens; D003169:Complement Inactivator Proteins; D018076:DNA, Complementary; C497859:Mcp protein, mouse; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins; D011994:Recombinant Proteins; D003165:Complement System Proteins; D050577:Complement C3-C5 Convertases