Analyses of monoclonal antibodies reactive with porcine CD5.
Among all monoclonal antibodies (mAbs) analyzed in the first porcine CD workshop, six mAbs showed reactivity to the porcine CD5 antigen (workshop mAbs 067, 068, 069, 070, 071 and 119). Because of lack of immunoprecipitation studies for five (067, 068, 069, 070 and 071) out of the six mAbs, only one mAb (119) could be definitely characterized as mAb against the monomeric 63 kDa porcine CD5 antigen. The five other mAbs included in this cluster are characterized by an identical labelling pattern in FCM and competition of the CD5 epitope recognized by mAb 119. These mAbs were allocated to the wCD5 subcluster.
Saalmüller
A
A
Federal Research Centre for Virus Diseases of Animals, Tübingen, Germany.
Aasted
B
B
Canals
A
A
Dominguez
J
J
Goldman
T
T
Lunney
J K
JK
Maurer
S
S
Pescovitz
M D
MD
Pospisil
R
R
Salmon
H
H
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D015703:Antigens, CD / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D018956:CD5 Antigens; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D005434:Flow Cytometry / Q000662:veterinary; D013552:Swine / Q000276:immunology*
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D018956:CD5 Antigens; D000939:Epitopes