[High mean pallor value--a risk factor for deterioration of the visual field in glaucoma and ocular hypertension. A pilot study using the optic nerve head analyzer].
Does the disc parameter "mean pallor value" suggest a risk for further deterioration of visual field defects?


METHODS
In 10 patients with ocular hypertension and 23 patients with primary open-angle glaucoma (Octopus 201, Humphrey perimeter) disc pallor was calculated by double examinations with the ONHA in 1987-1988, and a long-term follow-up of the visual field was performed. In all patients we also acquired information about the IOP level and visual field during the observation time from the ophthalmologists. Only one eye per patient was evaluated after randomized selection.


RESULTS
In ocular hypertensive patients only 1 of 10 eyes showed deterioration of the visual field. In the glaucoma group 4 eyes out of 23 showed an increase in visual field loss. The eyes with a tendency to deteriorate had a higher mean pallor value compared with the mean value of the corresponding group [ocular hypertensives: 0.40 compared to 0.31 +/- 0.07 (0.02); POAG: 0.50 +/- 0.06 (0.03) compared to 0.33 +/- 0.08 (0.02); mean value +/- SE (SEM)]. The difference was statistically significant in the glaucoma group; Wilcoxon, Mann and Whitney U-test; P < 0.005.


CONCLUSIONS
Taking into consideration all risk factors, the mean pallor value might help additionally to prognosticate the risk of deterioration of the visual field as far as 5-year follow-up allows this preliminary conclusion. The pallor value alone is not suitable for the follow-up of glaucoma patients because of the influence of increasing lens opacities and changes in the video system of the ONHA over years.
Siebert
M
M
Universitäts-Augenklinik Würzburg.
Gramer
E
E
Serguhn
S
S
D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D007429:Intraocular Pressure / Q000502:physiology; D009798:Ocular Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D019721:Ophthalmoscopes; D009898:Optic Disk / Q000503:physiopathology*; D010865:Pilot Projects; D011379:Prognosis; D058609:Visual Field Tests / Q000295:instrumentation; D014794:Visual Fields / Q000502:physiology*