[Substance P and vasoactive intestinal peptide in patients with progressive scleroderma. Determination of plasma level before and after autogenic training].
In 12 patients suffering from systemic sclerosis (SSc) the influence of autogenic training on the plasma level of the neuropeptides substance P and vasoactive intestinal peptide (VIP) was studied. Compared with healthy controls the SSc patients exhibited significantly elevated levels of substance P (mean +/- SD: 7.1 +/- 3.2 pmol/l vs 1.6 +/- 1.6 pmol/l). Apart from variations the VIP plasma concentration did not significantly differ from that in healthy controls (mean +/- SD 10.7 +/- 7.1 pmol/l versus 12.0 +/- 5.3 pmol/l). Autogenic training did not bring about any significant changes in the plasma levels of neuropeptides.
Haustein
U F
UF
Klinik und Poliklinik für Hautkrankheiten, Universität Leipzig.
Weber
B
B
Seikowski
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D001143:Arousal / Q000502:physiology*; D001326:Autogenic Training / Q000379:methods*; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000097:blood / Q000628:therapy; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology; D012595:Scleroderma, Systemic / Q000097:blood / Q000628:therapy*; D013373:Substance P / Q000097:blood*; D014660:Vasoactive Intestinal Peptide / Q000097:blood*
D013373:Substance P; D014660:Vasoactive Intestinal Peptide