Living-unrelated renal donor transplantation: the UNOS experience, 1987-1991. United Network for Organ Sharing.
1. LURD transplants were associated with excellent one-year graft survival of 92%. This survival was superior to that for cadaver transplants performed during the same period. 2. High-risk groups for LURDs are children (age < 18 years) and repeat transplant recipients. Both groups were associated with significantly decreased graft survival. 3. The effects of HLA matching and donor-specific transfusions are not significant. 4. Because of the critical shortage of donor organs and the increasing waiting time for renal transplantation, the use of LURDs can be recommended as a means to expand the number of available organs.
Geffner
S R
SR
Department of Surgery, University of Wisconsin, School of Medicine, Madison, USA.
D'Alessandro
A M
AM
Kalayoglu
M
M
Knechtle
S J
SJ
Pirsch
J D
JD
Belzer
F O
FO
Sollinger
H W
HW
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006085:Graft Survival; D006684:HLA-DR Antigens / Q000032:analysis; D006648:Histocompatibility; D006801:Humans; D007223:Infant; D016030:Kidney Transplantation / Q000276:immunology / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
D006684:HLA-DR Antigens