title: Giant intracranial aneurysm with rapid thrombus formation and intramural hemorrhage--case report.
abstract: A 50-year-old female presented with an unusual giant intracranial aneurysm that showed rapid, spontaneous thrombus formation and subsequent intramural hemorrhage. The thrombus appeared as a homogeneous area on magnetic resonance images, in contrast to the usual heterogeneous appearance. Two months after thrombus formation, the aneurysm had grown and developed intramural hemorrhage. The growth of giant intracranial aneurysms is related to neovascularization and recurrent intramural hemorrhage. The rapid formation of an intra-aneurysmal thrombus may stimulate neovascularization, resulting in intramural hemorrhage and aneurysmal growth.
authors.affiliation: Department of Neurosurgery, National Defense Medical College, Saitama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Maruishi
authors.forename: K
authors.initials: K
authors.lastname: Shima
authors.forename: H
authors.initials: H
authors.lastname: Chigasaki
authors.forename: K
authors.initials: K
authors.lastname: Tsuchiya
mesh_terms: D001488:Basilar Artery / Q000503:physiopathology*; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000209:etiology; D002552:Cerebral Ventricles / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013927:Thrombosis / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt