title: Initial lesion size as a predictive factor in determining the response of port-wine stains in children treated with the pulsed dye laser.
abstract: OBJECTIVE
  To evaluate the response of facial port-wine stains in children to pulsed (450 microseconds) dye (577- or 585-nm) laser treatment based on the age of the patient and the size of the port-wine stain at the initiation of treatments.
  
  
  METHODS
  Case series.
  
  
  METHODS
  Outpatient dermatology clinic at the University of Colorado School of Medicine, Denver.
  
  
  METHODS
  A consecutive sample of 83 children who had facial port-wine stains that were treated in their entirety at each visit.
  
  
  METHODS
  Patients were treated with a pulsed (450 microseconds) dye (577- and 585-nm) laser.
  
  
  METHODS
  Decrease in size of the port-wine stain.
  
  
  RESULTS
  Overall 18 (22%) of the 85 patients responded with complete clearing of their port-wine stains. The port-wine stains in 32% (7/22) of the patients who began treatment before 1 year of age responded with complete clearing of their port-wine stains compared with 18% (11/61) in older patients (P < .01). Fifteen (32%) of 47 patients with port-wine stains smaller than 20 cm2 at initial evaluation were totally cleared vs three (8%) of the 36 patients with port-wine stains larger than 20 cm2 (P < .05). This size effect is apparent at all ages.
  
  
  CONCLUSIONS
  When considering treatment for facial port-wine stains with pulsed dye lasers, it is important to consider not only the age of the child at the beginning of treatments, but also the initial size of the lesion.
authors.affiliation: Department of Dermatology, University of Colorado School of Medicine, Denver, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Morelli
authors.forename: W L
authors.initials: WL
authors.lastname: Weston
authors.forename: J C
authors.initials: JC
authors.lastname: Huff
authors.forename: J J
authors.initials: JJ
authors.lastname: Yohn
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005145:Face / Q000002:abnormalities*; D006222:Hamartoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007223:Infant; D053685:Laser Therapy / Q000379:methods; D011237:Predictive Value of Tests; D011379:Prognosis; D016896:Treatment Outcome