title: Number and sex of offspring of delta F508 carriers outside cystic fibrosis families.
abstract: Number and sex of offspring were determined in a group of 7,841 randomly selected blood donors who were screened for the delta F508 mutation. We did not find any evidence for differences in number or sex ratio of offspring between delta F508 carriers and non-carriers.
authors.affiliation: Department of Medical Genetics, University of Groningen, The Netherlands.
authors.forename: H G
authors.initials: HG
authors.lastname: de Vries
authors.forename: J M
authors.initials: JM
authors.lastname: Collée
authors.forename: W P
authors.initials: WP
authors.lastname: Meeuwsen
authors.forename: H
authors.initials: H
authors.lastname: Scheffer
authors.forename: L P
authors.initials: LP
authors.lastname: Ten Kate
mesh_terms: D001723:Birth Rate; D018118:Chloride Channels / Q000235:genetics; D003550:Cystic Fibrosis / Q000235:genetics / Q000503:physiopathology*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005260:Female; D006579:Heterozygote; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000235:genetics; D009154:Mutation; D012744:Sex Ratio
chemical_list: C505032:CFTR protein, human; D018118:Chloride Channels; D008565:Membrane Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator