High resolution matrix-assisted laser desorption/ionization time-of-flight analysis of single-stranded DNA of 27 to 68 nucleotides in length.
Mass spectra of single-stranded DNA oligonucleotides were acquired using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). Resolution enhancement using space-velocity correlation focusing allows for facile observation of different oligomers, the direct observation of individual DNA-metal adducts, and investigation of counter ion structure.
Christian
N P
NP
Department of Chemistry, Indiana University, Bloomington 47405, USA.
Colby
S M
SM
Giver
L
L
Houston
C T
CT
Arnold
R J
RJ
Ellington
A D
AD
Reilly
J P
JP
D001483:Base Sequence; D018736:DNA Adducts / Q000032:analysis; D004277:DNA, Single-Stranded / Q000032:analysis*; D008969:Molecular Sequence Data; D009841:Oligonucleotides / Q000032:analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet
D018736:DNA Adducts; D004277:DNA, Single-Stranded; D009841:Oligonucleotides