Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity.
Hruska
K A
KA
Division of Nephrology, Jewish Hospital/Washington University Medical Center, St. Louis, Missouri 63110, USA.
Rolnick
F
F
Huskey
M
M
Alvarez
U
U
Cheresh
D
D
D000595:Amino Acid Sequence; D000818:Animals; D002448:Cell Adhesion; D002478:Cells, Cultured; D066298:In Vitro Techniques; D016023:Integrins / Q000502:physiology*; D008969:Molecular Sequence Data; D010010:Osteoclasts / Q000502:physiology*; D053495:Osteopontin; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases; D010716:Phosphatidylinositols / Q000502:physiology; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000378:metabolism*; D016392:Proto-Oncogene Proteins pp60(c-src) / Q000378:metabolism; D016024:Receptors, Cytoadhesin / Q000502:physiology*; D019030:Receptors, Vitronectin; D012795:Sialoglycoproteins / Q000502:physiology*; D015398:Signal Transduction
D016023:Integrins; D010455:Peptides; D010716:Phosphatidylinositols; D016024:Receptors, Cytoadhesin; D019030:Receptors, Vitronectin; D012795:Sialoglycoproteins; D053495:Osteopontin; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D016392:Proto-Oncogene Proteins pp60(c-src)