Effects of thyro-parathyroidectomy and parathyroidectomy upon dentinogenesis: Part II: Electron microscopy.
An ultrastructural study was carried out in order to better characterize the findings observed in the first part of our study. The materials and methods are the same as those used in the preceding paper. This study reveals the occurrence of structures which display a symmetrical cross-banded pattern within the predentin and dentin of thyro-parathyroidectomized (TPTX) and parathyroidectomized (PTX) rats. A difference in the distribution of the symmetrical banded structures as dentinogenesis advances, as well as differences in the amount of the symmetrical banded structures between TPTX and PTX rats were observed. The symmetrical banded structures correspond with the so-called symmetrical SLS previously described in the incisor of normal and pathologic rats. The occurrence of these structures at a given stage of the incisor development suggests that the odontoblast is sensitive to the parathyroid hormone deficiency and/or hypocalcemia in a precise stage of its maturation.
Acevedo
A C
AC
CNRS URA, Paris, France.
Chardin
H
H
Septier
D
D
Staub
J F
JF
Goldberg
M
M
D000818:Animals; D003804:Dentin / Q000378:metabolism / Q000648:ultrastructure*; D003810:Dentinogenesis / Q000502:physiology*; D006996:Hypocalcemia / Q000503:physiopathology; D007180:Incisor; D008297:Male; D008854:Microscopy, Electron; D009804:Odontoblasts / Q000502:physiology / Q000648:ultrastructure; D010280:Parathyroid Glands / Q000637:transplantation; D010281:Parathyroid Hormone / Q000172:deficiency / Q000502:physiology*; D016105:Parathyroidectomy; D051381:Rats; D017208:Rats, Wistar; D013963:Thyroid Hormones / Q000502:physiology*; D013965:Thyroidectomy; D014182:Transplantation, Autologous
D010281:Parathyroid Hormone; D013963:Thyroid Hormones