title: Long-time etching at low pH jeopardizes periodontal healing.
abstract: The purpose of the present investigation was to examine whether the immediate necrotizing effects of low pH etching agents also impair periodontal healing in the long-term perspective. It was concluded that long-time etching (3 min) at low pH of root surfaces surrounded by vital periodontal issues resulted in impaired periodontal healing. In contrast, short-time etching appeared to promote connective tissue formation by preventing epithelialization of the periodontal wound despite its low pH. However, clinical inferences should be drawn with caution from the present results, since healing results recorded at 8 weeks may not prove to be stable, especially for those cases sensitive to the immediate influence of marginal infection such as connective tissue attachments and epithelial junctions, unless optimal oral hygiene is maintained. Furthermore, the choice of acid may be of importance.
authors.affiliation: Department of Oral Histology and Cell Biology, School of Dentistry, Karolinska Institutet, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Blomlöf
authors.forename: L
authors.initials: L
authors.lastname: Jansson
authors.forename: L
authors.initials: L
authors.lastname: Blomlöf
authors.forename: S
authors.initials: S
authors.lastname: Lindskog
mesh_terms: D000134:Acid Etching, Dental / Q000009:adverse effects* / Q000379:methods; D016301:Alveolar Bone Loss / Q000473:pathology / Q000601:surgery; D000539:Alveolar Process / Q000187:drug effects / Q000473:pathology; D000818:Animals; D000844:Ankylosis / Q000473:pathology; D003238:Connective Tissue / Q000187:drug effects / Q000473:pathology; D003739:Dental Cementum / Q000187:drug effects / Q000473:pathology; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005889:Gingival Recession / Q000473:pathology / Q000601:surgery; D006863:Hydrogen-Ion Concentration; D008252:Macaca fascicularis; D009336:Necrosis; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000473:pathology / Q000601:surgery*; D010514:Periodontal Pocket / Q000473:pathology / Q000601:surgery; D010519:Periodontium / Q000187:drug effects / Q000473:pathology; D010756:Phosphoric Acids / Q000008:administration & dosage / Q000009:adverse effects*; D013524:Surgical Flaps; D013997:Time Factors; D014092:Tooth Root / Q000187:drug effects / Q000473:pathology; D014945:Wound Healing
chemical_list: D010756:Phosphoric Acids