[The immunological and cytogenetic changes in patients with pulmonary tuberculosis].
The performed studies showed that patients with active phase pulmonary tuberculosis have their T-system function suppressed, that of B-system activated, this phenomenon being the most marked in those patients with fibrocavernous tuberculosis. Increase in the activity of phagocytes was more common in patients with infiltrative tuberculosis. The immunity system state in subjects with non-active post tuberculous alterations did not depart from normal values. DNA and RNA concentrations were decreased in those patients having more pronounced immunologic disturbances (infiltrative and fibrocavernous tuberculosis), reparative capacity of RNA being altered only in patients with focal tuberculosis. Strong correlation was established between immunologic and cytogenetic indices.
Chernushenko
E F
EF
Naĭda
I V
IV
Ryzhkova
N A
NA
Panasiukova
O R
OR
Didyk
T V
TV
D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D004247:DNA / Q000097:blood; D004260:DNA Repair; D006801:Humans; D009504:Neutrophils / Q000276:immunology / Q000378:metabolism; D010586:Phagocytes / Q000276:immunology / Q000378:metabolism; D012313:RNA / Q000097:blood; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism; D014391:Tuberculosis, Miliary / Q000097:blood / Q000235:genetics / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000235:genetics* / Q000276:immunology*
D012313:RNA; D004247:DNA