title: [Pregnancy in Takayasu arteritis].
abstract: We report the course of pregnancy in a patient with Takayasu's arteritis type I and describe the diagnostical and therapeutical management with repeated Doppler-sonography. Immunosuppressive therapy was reduced in pregnancy and could be maintained on a low level even after delivery. In the third trimester arterial blood pressure raised up to 190/60 mm Hg and was sufficiently lowered by prescription of verapamil. Repeated Doppler-sonographic investigation beginning with 20 weeks of gestation revealed indices in the normal range during the whole pregnancy. After 37 weeks of gestation a healthy infant was delivered vaginally. The post partum course was uneventful.
authors.affiliation: Universitätsfrauenklinik Charité, Humboldt-Universität zu Berlin.
authors.forename: M
authors.initials: M
authors.lastname: Bloechle
authors.forename: R
authors.initials: R
authors.lastname: Bollmann
authors.forename: R
authors.initials: R
authors.lastname: Chaoui
authors.forename: M
authors.initials: M
authors.lastname: Birnbaum
authors.forename: S
authors.initials: S
authors.lastname: Bartho
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001379:Azathioprine / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005865:Gestational Age; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange / Q000187:drug effects / Q000502:physiology; D008775:Methylprednisolone / Q000009:adverse effects / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000000981:diagnostic imaging / Q000188:drug therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D014700:Verapamil; D001379:Azathioprine; D008775:Methylprednisolone