title: Substitution of mivacurium for succinylcholine for ECT in elderly patients.
abstract: Three cases are reported where pre-existing medical conditions (severe osteoporosis, amyotrophic lateral sclerosis, cardiac arrhythmias) made the administration of succinylcholine during ECT potentially dangerous. Therefore, mivacurium was substituted as the muscle relaxant necessary for safe therapy. Full reversal of the non-depolarizing muscle relaxant was assured by post-reversal use of the peripheral nerve stimulator with full recovery of train-of-four response.
authors.affiliation: Anesthesiology Service, Veterans Administration Medical Centre, Albuquerque, NM, USA.
authors.forename: K
authors.initials: K
authors.lastname: Janis
authors.forename: J
authors.initials: J
authors.lastname: Hess
authors.forename: J A
authors.initials: JA
authors.lastname: Fabian
authors.forename: M
authors.initials: M
authors.lastname: Gillis
mesh_terms: D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000628:therapy; D000075202:Contraindications; D004565:Electroconvulsive Therapy; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D000077590:Mivacurium; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents / Q000627:therapeutic use*; D010024:Osteoporosis / Q000628:therapy; D013390:Succinylcholine
chemical_list: D007546:Isoquinolines; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents; D000077590:Mivacurium; D013390:Succinylcholine