title: Color Doppler ultrasonography for the assessment of renal blood flow in heart failure.
abstract: To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we compared left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by iodine 123-123I-p-aminohippuric acid (PAH) scintigraphy in 19 patients with heart failure and 7 normal control subjects. Single-side and total RBF estimates by echo-Doppler ranged, respectively, between 179 and 428 mL/min/m2 and from 378 to 835 mL/min/m2 in patients with heart failure and between 265 and 601 mL/min/m2 and from 564 to 1,182 mL/min/m2 in normal control subjects. Single-side and total RBF estimates by echo-Doppler correlated well with measurements obtained by scintigraphy (r = 0.74 and 0.76, respectively, in patients with heart failure; both: p < 0.001). At Bland and Altman's analysis of correspondence between the 2 techniques, there were 17 disagreements (33.7%) for single-side RBF and 8 disagreements (31.8%) for total RBF. However, the two techniques disagreed markedly in only two single-side and one total RBF estimates. Thus, in patients with heart failure, RBF assessed noninvasively by color Doppler ultrasonography has a good correlation with 123I-PAH renal scintigraphy data over a wide range of blood flow.
authors.affiliation: Department of Cardiology, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Vigna
authors.forename: A
authors.initials: A
authors.lastname: Russo
authors.forename: F
authors.initials: F
authors.lastname: Barbano
authors.forename: S
authors.initials: S
authors.lastname: Fusilli
authors.forename: F
authors.initials: F
authors.lastname: Loperfido
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D015902:Gamma Cameras / Q000706:statistics & numerical data; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011877:Radionuclide Imaging; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012079:Renal Circulation; D018615:Ultrasonography, Doppler, Color / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D010130:p-Aminohippuric Acid
chemical_list: D007457:Iodine Radioisotopes; D010130:p-Aminohippuric Acid