title: [Spontaneous histamine release by basophils and bronchial hyperreactivity in patients with hay fever].
abstract: Basophil spontaneous histamine release test was performed in seventeen patients suffered from seasonal allergic rhinitis before, 2 weeks after immunotherapy and during pollen season. During pollen season at the same day non-specific bronchial hyperreactivity to histamine was estimated. Values of spontaneous basophil histamine release before immunotherapy were not different from control group but significantly increased after immunotherapy and during pollen season. There was no correlation between degree of nonspecific bronchial hyperreactivity and values of spontaneous histamine release from basophils.
authors.affiliation: Katedry i Kliniki Chorób Wewnetrznych i Alergologii Akademii Medycznej we Wrocławiu.
authors.forename: W
authors.initials: W
authors.lastname: Medrala
authors.forename: J
authors.initials: J
authors.lastname: Małolepszy
authors.forename: A
authors.initials: A
authors.lastname: Wolańczyk-Medrala
authors.forename: M
authors.initials: M
authors.lastname: Wrzyszcz
authors.forename: R
authors.initials: R
authors.lastname: Rybakiewicz
authors.forename: M
authors.initials: M
authors.lastname: Litwa
mesh_terms: D000485:Allergens / Q000627:therapeutic use*; D052179:Antigens, Plant / Q000627:therapeutic use; D001491:Basophils / Q000276:immunology*; D016535:Bronchial Hyperreactivity / Q000276:immunology / Q000628:therapy*; D004338:Drug Combinations; D005976:Glutaral / Q000627:therapeutic use*; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans; D007167:Immunotherapy; D016011:Normal Distribution; D010936:Plant Extracts / Q000627:therapeutic use*; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy*; D014443:Tyrosine / Q000627:therapeutic use*
chemical_list: D000485:Allergens; D052179:Antigens, Plant; D004338:Drug Combinations; D010936:Plant Extracts; D014443:Tyrosine; C014155:Parietaria judaica pollen; D005976:Glutaral