title: Treatment of invasive squamous cell carcinoma complicating anal Buschke-Löwenstein tumor: a case history.
abstract: We present here the case of a patient with Buschke-Löwenstein tumor of the anus complicated by invasive squamous cell carcinoma metastatic to the inguinal and periaortic pelvic lymph nodes. Successful local palliation was achieved with 5-fluorouracil and mitomycin-C-based chemotherapy combined with radiation therapy, but systemic progression was unaffected.
authors.affiliation: Division of Medical Oncology, JHM Health Center, Gainesville, Florida 32610-0277, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Marsh
authors.forename: D
authors.initials: D
authors.lastname: Agaliotis
authors.forename: R
authors.initials: R
authors.lastname: Killeen
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D001004:Anus Diseases / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D001005:Anus Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009361:Neoplasm Invasiveness; D010166:Palliative Care
chemical_list: D016685:Mitomycin; D005472:Fluorouracil