title: Migraine in children.
abstract: A descriptive study was carried out to find out the clinical profile, and electroencephalographic (EEG) changes in children with migraine. Screening for urinary excretion of 5-hydroxy indole acetic acid (5-HIAA) was carried out. Fifty children suffering from migraine as per Prensky's criteria were recruited over a period of 1 year. Forty six children were suffering from common migraine and 4 had classic migraine. The most common precipitating factors were physical strain and psychological stress like examination fear, fear of teacher and fights with friends. Abnormal EEG recordings were seen in 35 out of 50 patients. Urine samples taken during the headache free period were negative for 5 HIAA. Among the samples taken during the episode of headache, only 1 was positive for 5-HIAA. It is concluded that common migraine is more prevalent than classic migraine. Clinical criteria is the only way of diagnosing migraine. Since EEG changes are non-specific, this cannot be used as a diagnostic test. Biochemical analysis is expensive and less sensitive.
authors.affiliation: Clinical Epidemiology Unit, Institute of Child Health, Madras.
authors.forename: N
authors.initials: N
authors.lastname: Thilothammal
authors.forename: M
authors.initials: M
authors.lastname: Chellaraj
authors.forename: K
authors.initials: K
authors.lastname: Banu
authors.lastname: Ratnam
mesh_terms: D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004569:Electroencephalography; D005192:Family Health; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000652:urine; D008297:Male; D008487:Medical History Taking; D008881:Migraine Disorders / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D015985:Precipitating Factors; D013315:Stress, Psychological
chemical_list: D006897:Hydroxyindoleacetic Acid