title: Administration of granulocyte colony-stimulating factor to neutropenic low birth weight infants of mothers with preeclampsia.
abstract: Nine low birth weight infants with neutropenia born to mothers with preeclampsia were treated with granulocyte-colony stimulating factor, 10 micrograms/kg intravenously, within 24 hours of birth and at 24-hour intervals for a maximum of three doses if neutropenia persisted. The absolute neutrophil count increased significantly in eight of the nine infants within 6 hours, and neutrophilia was sustained for at least 72 hours after administration of a single dose of granulocyte-colony stimulating factor.
authors.affiliation: Department of Pediatrics, University of North Carolina at Chapel Hill 27599-7596.
authors.forename: R A
authors.initials: RA
authors.lastname: Makhlouf
authors.forename: M W
authors.initials: MW
authors.lastname: Doron
authors.forename: C L
authors.initials: CL
authors.lastname: Bose
authors.forename: W A
authors.initials: WA
authors.lastname: Price
authors.forename: A D
authors.initials: AD
authors.lastname: Stiles
mesh_terms: D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D007230:Infant, Low Birth Weight / Q000097:blood; D007231:Infant, Newborn; D007958:Leukocyte Count; D009503:Neutropenia / Q000209:etiology / Q000628:therapy*; D009504:Neutrophils; D011225:Pre-Eclampsia; D011247:Pregnancy
chemical_list: D016179:Granulocyte Colony-Stimulating Factor