title: Intervening in GERD: the phases of management.
abstract: The discomforts and histologic changes of gastroesophageal reflux disease call for a stepped approach consisting of four phases: lifestyle modification, initiation of pharmacologic therapy, intensification of drug therapy, and in some cases antireflux surgery. Decisions are guided by symptom patterns, which serve to suggest the predominant pathophysiologic mechanisms.
authors.affiliation: Temple University, Philadelphia, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Horwitz
authors.forename: R S
authors.initials: RS
authors.lastname: Fisher
mesh_terms: D000359:Aftercare; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001471:Barrett Esophagus / Q000209:etiology; D003663:Decision Trees; D003937:Diagnosis, Differential; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged
chemical_list: D000897:Anti-Ulcer Agents