title: Interleukin-8 production by human mesothelial cells after direct stimulation with staphylococci.
abstract: Mesothelial cells (MC) are able to produce interleukin-8 (IL-8) after stimulation with IL-1 beta or tumor necrosis factor alpha. The aim of our study was to investigate whether MC are able to produce IL-8 after direct stimulation with clinically relevant bacteria. We observed a significant IL-8 response by the MC which were directly stimulated with viable staphylococci.
authors.affiliation: Department of Cell Biology & Immunology, Faculty of Medicine, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
authors.forename: C E
authors.initials: CE
authors.lastname: Visser
authors.forename: J J
authors.initials: JJ
authors.lastname: Steenbergen
authors.forename: M G
authors.initials: MG
authors.lastname: Betjes
authors.forename: S
authors.initials: S
authors.lastname: Meijer
authors.forename: L
authors.initials: L
authors.lastname: Arisz
authors.forename: E C
authors.initials: EC
authors.lastname: Hoefsmit
authors.forename: R T
authors.initials: RT
authors.lastname: Krediet
authors.forename: R H
authors.initials: RH
authors.lastname: Beelen
mesh_terms: D002478:Cells, Cultured; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology; D016209:Interleukin-8 / Q000096:biosynthesis*; D013210:Staphylococcus / Q000502:physiology*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
chemical_list: D007375:Interleukin-1; D016209:Interleukin-8; D014409:Tumor Necrosis Factor-alpha