[The role of the hepatitis B, C and D viruses in the etiology of chronic hepatopathies in Cluj].
OBJECTIVE
We studied the prevalence of viral hepatitis B, C and D markers in chronic hepatopathies from Cluj.


METHODS
Sera of 297 patients with chronic hepatopathies (236 adults and 61 children) have been tested for viral hepatitis markers: HBsAg, anti-HBc, anti-HBs, HBeAg, anti-HBe, anti-HDV, anti-HCV, by automated ELISA.


RESULTS
HBV infection markers in 32% (adults) and 4.9% (children), and HDV infection markers in 11.8% (adults) and 26.3% (children). Double (HBV and HCV) and triple infection (HBV, HDV and HCV) were observed in 28.4% (adults), 4.9% (children), and 3.4% (adults), 0% (children), respectively.


CONCLUSIONS
Hepatitis virus infection markers, especially HBV and HCV play an important role in the determinism of chronic hepatopathies from Cluj area, both in children and adults.
Neamţu
A
A
Universitatea de Medicină şi Farmacie, Cluj-Napoca.
Pascu
O
O
Szanto
P
P
Chira
O
O
Neamţu
D
D
State
D
D
D000328:Adult; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D002648:Child; D002908:Chronic Disease; D006508:Hepatitis Antibodies / Q000097:blood; D018963:Hepatitis Antigens / Q000097:blood; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology; D003699:Hepatitis D / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D012383:Romania / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D014505:Urban Population / Q000706:statistics & numerical data
D015415:Biomarkers; D006508:Hepatitis Antibodies; D018963:Hepatitis Antigens