Liver transplantation in patients with Budd-Chiari syndrome.
Patients with Budd-Chiari syndrome (obstruction of the hepatic veins) and associated hepatic insufficiency may be candidates for orthotopic liver transplantation (OLT). In our series of 405 OLT patients, 3 were transplanted due to Budd-Chiari syndrome (0.7%). The indication for liver transplantation in these patients was severe hepatic insufficiency (chronic in two and acute in the third one). Morphologic study of the obstructions revealed apparently different causes, including thrombi, membranous webs in hepatic veins, and hydatid cyst compression. The surgical technique employed in these transplantations was similar to that for other etiologies. Due to its implications for the future course of OLT, it is important to determine the exact etiology of Budd-Chiari syndrome in the pretransplant period and to treat the patients with early and long-term anticoagulant therapy to avoid syndrome recurrence.
Gomez
R
R
Department of General and Digestive Surgery, University Hospital 12 de Octubre, Madrid, Spain.
Moreno
E
E
Colina
F
F
Gonzalez
I
I
Loinaz
C
C
Garcia
I
I
Trombatore
G
G
Garcia
H
H
Chamorro
A
A
Medina
E
E
D000293:Adolescent; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D006502:Budd-Chiari Syndrome / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation; D008297:Male; D012189:Retrospective Studies
D000925:Anticoagulants; D007166:Immunosuppressive Agents