[Clinical and experimental studies on tiaoshen liquor for infantile hyperkinetic syndrome].
One hundred children with hyperkinetic syndrome were treated by using Tiaoshen Liquor (TL) consisted of Chinese herbal drugs. After the treatment, the behavior grading lowered greatly, their attention was improved, and their academic records raised. The total effective rate reached 94%. The results of the animal experiments showed that TL could reduce the spontaneous activities of the healthy mice, thus lowering remarkably the spontaneous activities in the mice with hyperkinetic behavior caused by taking scopolamine; reinforce the learning memory in the healthy mice; and improve in different degrees the learning memory of the mice with dysmnesia caused by administering scopolamine, sodium nitrite and alcohol respectively, which indicate that the therapeutic mechanism of TL for this syndrome was probably related to the improvement of information transfer function of the cholinergic neuron synapses of central nervous system and to the enhancement of hypoxia tolerence of the cerebral tissues.
Wang
L H
LH
Pediatric Dept. of the Affiliated Hospital of Shandong College of TCM, Jinan.
Li
C S
CS
Li
G Z
GZ
D000818:Animals; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D002648:Child; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000139:chemically induced / Q000188:drug therapy; D051379:Mice; D012601:Scopolamine
D004365:Drugs, Chinese Herbal; D012601:Scopolamine