title: Antibody-induced alterations of protein and nucleic acid metabolism during experimental thyroglobulin immunization.
abstract: The protein and nucleic acid contents of liver, spleen, muscle, kidney, and brain were studied in experimental autoimmune thyroiditis. Protein and ribonucleic acid levels showed a positive increase in the case of liver, spleen, and muscle on days 56 and 98 after immunization and on day 147 they reached control levels. Spleen deoxyribonucleic acid showed a significant increase on day 56, whereas the other days showed no change. Kidney and brain tissue revealed no change.
authors.affiliation: Department of Animal Physiology, Bose Institute, Calcutta, India.
authors.forename: S
authors.initials: S
authors.lastname: Lahiri
authors.forename: A
authors.initials: A
authors.lastname: Chakraborty
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis; D007114:Immunization; D007457:Iodine Radioisotopes; D008297:Male; D009696:Nucleic Acids / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis; D011817:Rabbits; D013954:Thyroglobulin / Q000276:immunology*; D013967:Thyroiditis, Autoimmune / Q000378:metabolism*
chemical_list: D001798:Blood Proteins; D007457:Iodine Radioisotopes; D009696:Nucleic Acids; D011506:Proteins; D012313:RNA; D004247:DNA; D013954:Thyroglobulin