Lyme vaccine enhancement. N-terminal acylation of a protein antigen and inclusion of a saponin adjuvant.
Coughlin
R T
RT
Cambridge Biotech Corporation, Worcester, Massachusetts 01605, USA.
Ma
J
J
Cox
D E
DE
D000215:Acylation; D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000595:Amino Acid Sequence; D000818:Animals; D000942:Antigens, Bacterial / Q000737:chemistry / Q000276:immunology*; D001426:Bacterial Proteins / Q000276:immunology; D001428:Bacterial Vaccines / Q000737:chemistry / Q000276:immunology* / Q000627:therapeutic use; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D006801:Humans; D008074:Lipoproteins / Q000276:immunology; D008193:Lyme Disease / Q000276:immunology* / Q000382:microbiology / Q000517:prevention & control*; D008969:Molecular Sequence Data; D012503:Saponins / Q000494:pharmacology*
D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D008074:Lipoproteins; D012503:Saponins