title: [Horizontal transmission of hepatitis C virus to family members of infected polytransfused pediatric patients].
abstract: The aim of this study is to evaluate the prevalence of the HCV antibodies in the relatives of polytransfused patients with different haemoglobinopathies. Our results have shown that 4.7% of relatives are aHCV positive. This incidence is much higher than that one reported in scientific publications with regard to non-haemoglobinopathis aHCV positive patients. Therefore a careful prevention and surveillance is needed in order to avoid the risk of infection in these subjects.
authors.affiliation: Servizio per la Prevenzione e la Cura delle Talassemie, P.O. Umberto I, Siracusa, Italia.
authors.forename: A
authors.initials: A
authors.lastname: Mangiagli
authors.forename: S
authors.initials: S
authors.lastname: Campisi
authors.forename: L
authors.initials: L
authors.lastname: Piazza
authors.forename: D
authors.initials: D
authors.lastname: Lo Monaco
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000276:immunology / Q000628:therapy; D001803:Blood Transfusion; D016026:Bone Marrow Transplantation / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006453:Hemoglobinopathies; D016174:Hepacivirus / Q000276:immunology / Q000302:isolation & purification*; D006508:Hepatitis Antibodies / Q000276:immunology*; D006526:Hepatitis C / Q000276:immunology / Q000635:transmission*; D018937:Hepatitis C Antibodies; D006801:Humans; D008297:Male; D065227:Transfusion Reaction; D017086:beta-Thalassemia / Q000276:immunology / Q000628:therapy*
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies