title: A plasmid-borne O-antigen chain length determinant and its relationship to other chain length determinants.
abstract: We identify a function-controlling O antigen chain length for a plasmid-borne gene, cldpHS-2, harboured by Flexneri strains of Escherichia coli known to cause reactive arthritis. The predicted amino acid sequence of the gene product is very similar to those of other cld genes and that of fepE, thought to be part of the enterobactin iron uptake system of E. coli. The predicted proteins are compared with rfb-associated chain length determinants as a family of related genes.
authors.affiliation: Department of Microbiology, University of Sydney, New South Wales, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Stevenson
authors.forename: A
authors.initials: A
authors.lastname: Kessler
authors.forename: P R
authors.initials: PR
authors.lastname: Reeves
mesh_terms: D000595:Amino Acid Sequence; D016918:Arthritis, Reactive / Q000382:microbiology; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial; D006801:Humans; D008969:Molecular Sequence Data; D019081:O Antigens; D010802:Phylogeny; D010957:Plasmids; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis / Q000235:genetics*; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D015011:Yersinia pseudotuberculosis / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D019081:O Antigens; D011135:Polysaccharides, Bacterial; C489586:wzzB protein, E coli; C075969:rol protein, Bacteria