Costello syndrome: the natural history of a true postnatal growth retardation syndrome.
We present the natural history of a female child with Costello syndrome from birth to the present age of 12 years. The diagnostic clinical signs combined with a true postnatal growth retardation are illustrated.
Umans
S
S
Center for Human Genetics, University of Leuven, Belgium.
Decock
P
P
Fryns
J P
JP
D000015:Abnormalities, Multiple / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D004392:Dwarfism / Q000235:genetics*; D005147:Facial Bones / Q000002:abnormalities; D019066:Facies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000235:genetics*; D009123:Muscle Hypotonia / Q000235:genetics; D012886:Skull / Q000002:abnormalities; D013577:Syndrome