title: Cerebral arterial spasm--a clinical review.
abstract: A review of the literature on cerebral vasospasm after aneurysmal subarachnoid haemorrhage (SAH) has shown that angiographic vasospasm occurs in 67.3% of cases when angiography is timed for the highest likelihood, and delayed ischaemic deficit or symptomatic vasospasm in 32.6%. The presence of vasospasm has a marked effect on overall outcome of SAH, and the outcome of delayed ischaemia itself is in about one-third death and in one-third permanent deficit. Management with fluid loading or induced hypertension and with calcium antagonists has been reported widely for both prevention and treatment, and can reduce the incidence and improve the outcome of vasospasm. Other forms of treatment including tissue plasminogen activator, aminosteroids and transluminal angioplasty also appear useful. In spite of these improved therapeutic possibilities, large numbers of patients are still being reported in whom no specific treatment is used.
authors.affiliation: Department of Neurosurgery, Westmead Hospital, Sydney, Australia.
authors.forename: N W
authors.initials: NW
authors.lastname: Dorsch
mesh_terms: D000800:Angioplasty, Balloon; D001794:Blood Pressure; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002533:Cerebral Angiography; D002946:Cisterna Magna; D004322:Drainage; D006438:Hemodilution; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000517:prevention & control; D011379:Prognosis; D007507:Therapeutic Irrigation
chemical_list: D002121:Calcium Channel Blockers