title: Late-onset focal dermal elastosis: clinical and histological features.
abstract: We describe two patients with lesions clinically resembling pseudoxanthoma elasticum and histologically exhibiting focal elastosis, with normal-appearing elastic fibres in the mid- and deep dermis. We consider that these skin lesions represent a previously undescribed entity, whose pathogenesis appears to be related to the ageing process.
authors.affiliation: Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tajima
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Izumi
authors.forename: S
authors.initials: S
authors.lastname: Kurihara
authors.forename: T
authors.initials: T
authors.lastname: Harada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology*; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology*