Production of granulocyte colony-stimulating factor by malignant mesothelioma.
We present the case of a male patient, aged 45 yrs, with malignant mesothelioma producing granulocyte colony-stimulating factor (G-CSF). The diagnosis was established by histopathological examination of the autopsied pleural tissues. Production of G-CSF was confirmed by immunoperoxidase staining, using a specific monoclonal antibody against recombinant G-CSF (rhG-CSF).
Rikimaru
T
T
Dept of Medicine, University School of Medicine, Kurume, Japan.
Ichikawa
Y
Y
Ogawa
Y
Y
Higuchi
E
E
Kinosita
M
M
Oizumi
K
K
Shima
I
I
D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000378:metabolism*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000378:metabolism*
D016179:Granulocyte Colony-Stimulating Factor