[Influenza A virus antigens in children with congenital pathology of central nervous system].
The latent circulation of influenza A virus in nursing home children with congenital central nervous abnormality was studied during 1989-1993 by the present-day diagnostic methods for detection of viral antigens. The influenza A virus antigen detection rates correlated with age, genetic predisposition, prior acute respiratory diseases in mothers during their pregnancy. There is evidence for long-term (up to 17 months) detection of influenza virus antigens in nasal secretions, as well as for prolonged (up to 7 months) detection of the same genomic sequences of HA gene both in leukocytes and nasal washes.
Kaprova
L S
LS
Sominina
A A
AA
Popova
T L
TL
Lipina
N V
NV
Zibina
E A
EA
Grinbaum
E B
EB
Rodionova
V B
VB
D000956:Antigens, Viral / Q000032:analysis*; D002493:Central Nervous System Diseases / Q000151:congenital* / Q000235:genetics / Q000821:virology*; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D016679:Genome, Viral; D006801:Humans; D007223:Infant; D009980:Influenza A virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013997:Time Factors; D017735:Virus Latency
D000956:Antigens, Viral