title: Epstein-Barr virus replication studies and their application to vector design.
abstract: Vectors containing elements of the Epstein-Barr virus genome are used primarily to maintain cloned DNA inserts as plasmids in mammalian cells. However, Epstein-Bar-virus-based vectors have also been valuable tools in the hands of those studying the life cycle of Epstein-Barr virus. In this article, we discuss those characteristics of Epstein-Barr virus and its life cycle that have been used in vector construction and describe methods that are particularly applicable to the use of Epstein-Barr-virus-based vectors.
authors.affiliation: Department of Molecular Pathology, University College London Medical School, UK.
authors.forename: P M
authors.initials: PM
authors.lastname: Brickell
authors.forename: M S
authors.initials: MS
authors.lastname: Patel
mesh_terms: D004261:DNA Replication; D004279:DNA, Viral / Q000502:physiology; D005822:Genetic Vectors; D004854:Herpesvirus 4, Human / Q000502:physiology*; D014779:Virus Replication
chemical_list: D004279:DNA, Viral