title: Complete response of a persistent ectopic pregnancy to dactinomycin after methotrexate failure. A case report.
abstract: Chemotherapy has become an accepted alternative for patients with persistent ectopic pregnancy, and methotrexate is the principal agent used. A patient with a persistent ectopic tubal pregnancy that failed to respond to methotrexate chemotherapy was treated with dactinomycin, with a complete response.
authors.affiliation: Department of Obstetrics and Gynecology, University of Massachusetts Medical Center, North Worcester, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Neary
authors.forename: P G
authors.initials: PG
authors.lastname: Rose
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D003609:Dactinomycin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D010446:Peptide Fragments / Q000097:blood; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*
chemical_list: D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D003609:Dactinomycin; D008727:Methotrexate