title: Molecular epidemiology of HIV-1 in Madrid.
abstract: Thirteen HIV-1 isolates from patients of different risk groups in Madrid (Spain) have been analyzed at the genetic level. Two distinct lineages of subtype B have been detected among the HIV-1 circulating in this area: one was related to SF-2/RF strains, whereas the other consists of a more heterogeneous group related to reference strain III-B. Variants of each lineage appeared to circulate preferentially within a risk group: III-B among intravenous drug users, and RF/SF-2 among male homosexuals.
authors.affiliation: Centro de Biología Celular y Retrovirus, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Rojas
authors.forename: J
authors.initials: J
authors.lastname: Dopazo
authors.forename: I
authors.initials: I
authors.lastname: Nájera
authors.forename: S
authors.initials: S
authors.lastname: Sánchez-Palomino
authors.forename: I
authors.initials: I
authors.lastname: Olivares
authors.forename: M J
authors.initials: MJ
authors.lastname: Martin
authors.forename: A
authors.initials: A
authors.lastname: Bernal
authors.forename: A
authors.initials: A
authors.lastname: García Saiz
authors.forename: R
authors.initials: R
authors.lastname: Nájera
authors.forename: C
authors.initials: C
authors.lastname: López-Galíndez
mesh_terms: D000328:Adult; D001483:Base Sequence; D002648:Child; D002675:Child, Preschool; D005260:Female; D005814:Genes, Viral / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology / Q000382:microbiology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D013030:Spain / Q000453:epidemiology; D013045:Species Specificity