title: An evaluation of FASTMAP with emphasis on fine-mapping.
abstract: We present an evaluation of the FASTMAP method with special reference to the issue of fine-mapping, using both 'real-life' and constructed data, and demonstrate some of the shortcomings of the method. Since the advantages of FASTMAP in terms of savings in computer resources compared to LINK-MAP are enormous, further improvements of the FASTMAP method would be highly desirable.
authors.affiliation: Abteilung für pädiatrische Genetik der LMU, München, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Müller
authors.forename: A
authors.initials: A
authors.lastname: Golla
mesh_terms: D002874:Chromosome Mapping; D005260:Female; D006801:Humans; D008126:Lod Score; D008297:Male; D010375:Pedigree; D012984:Software