Sequence of an exon of the canine p53 gene--mutation in a papilloma.
Exon 8 of tumour suppressor gene p53 was sequenced in domestic dogs. Ten nucleotide differences were revealed in a comparison with the feline sequence. A mutation ACT-->TCT (threonine-->serine) in codon 284 was detected in a papilloma of the oral mucosa.
Mayr
B
B
Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.
Schellander
K
K
Schleger
W
W
Reifinger
M
M
D000818:Animals; D001483:Base Sequence; D017931:DNA Primers / Q000737:chemistry; D004273:DNA, Neoplasm / Q000737:chemistry; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005091:Exons / Q000235:genetics*; D016158:Genes, p53 / Q000235:genetics*; D008969:Molecular Sequence Data; D009062:Mouth Neoplasms / Q000235:genetics / Q000662:veterinary*; D009154:Mutation; D010212:Papilloma / Q000235:genetics / Q000662:veterinary*
D017931:DNA Primers; D004273:DNA, Neoplasm