title: [The potentials of local and intravascular laser irradiation for eliminating the immunological disorders in patients with chronic pyelonephritis].
abstract: 61 patients suffering from chronic pyelonephritis in the stage of active inflammation associated with either urolithiasis (67.4%) or prostatic adenoma (32.6%) were divided into three groups. Group 1 received conventional antibacterial treatment, group 2 conventional treatment + local laser radiation (LLR), group 3 received combined therapy including intravascular laser irradiation of blood (IVLIB). The treatments efficacy was controlled by urine seeding for microflora and its sensitivity to antibiotics, by immunological supervision. The patients were found to have immunological abnormalities in the form of cellular and humoral immunity suppression, neutrophil phagocytic hypoactivity, elevated levels of medium-molecular peptides nonresponsive to standard antibacterial therapy. Adjuvant use of LLR improved humoral immunity and reduced total urine bacterial count. LLR replacement for IVLIB resulted in a complete regression of immunological shifts and more pronounced reduction of urinary bacterial contamination.
authors.forename: A I
authors.initials: AI
authors.lastname: Neĭmark
authors.forename: Z T
authors.initials: ZT
authors.lastname: Malazoniia
authors.forename: E B
authors.initials: EB
authors.lastname: Karabasova
mesh_terms: D000917:Antibody Formation / Q000528:radiation effects; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007154:Immune System Diseases / Q000209:etiology / Q000276:immunology / Q000532:radiotherapy*; D007111:Immunity, Cellular / Q000528:radiation effects; D053685:Laser Therapy; D008297:Male; D008722:Methods; D011470:Prostatic Hyperplasia / Q000150:complications; D011704:Pyelonephritis / Q000150:complications / Q000209:etiology / Q000276:immunology / Q000532:radiotherapy*; D014545:Urinary Calculi / Q000150:complications