Aplasia cutis congenita: a rare cause of elevated alpha-fetoprotein levels.
We present a catastrophic case of aplasia cutis congenita from a pregnancy complicated by elevated maternal serum and amniotic fluid alpha-fetoprotein levels and a positive acetylcholinesterase. Delivery occurred at 27 weeks 1 day after premature rupture of membranes with chorioamnionitis. The neonate lacked > 90% of its skin and died.
Gerber
M
M
Department of Obstetrics and Gynecology, Long Beach Medical Center, California.
de Veciana
M
M
Towers
C V
CV
Devore
G R
GR
D000110:Acetylcholinesterase / Q000032:analysis; D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry / Q000201:enzymology; D004476:Ectodermal Dysplasia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy / Q000097:blood; D011296:Prenatal Diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins; D000110:Acetylcholinesterase