title: Self-induced photogenic seizures in a child with severe myoclonic epilepsy in infancy: optical investigations and treatments.
abstract: In a 2-year-old patient with severe myoclonic epilepsy in infancy, we studied self-induced photogenic seizures using optical filters and blue-tinted contact lenses. The patient induced absences and/or myoclonic jerks by two kinds of behaviors: flickering hand movement (FHM) and forced eye closure (FEC). The placebo inhibitory effect on FHM by a blank goggle frame indicated that acquisition of learning affected the frequency of FHMs per se. Optical studies suggested that the degree of absorption from approximately 600-700 nm might determine the inhibitory effect of filters on FHM. Investigations using contact lenses showed that blue-tinted lenses gradually reduced photosensitivity and inhibited FHMs.
authors.affiliation: National Epilepsy Center, Shizuoka Higashi Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Shigematsu
authors.forename: T
authors.initials: T
authors.lastname: Fujiwara
authors.forename: K
authors.initials: K
authors.lastname: Yagi
authors.forename: M
authors.initials: M
authors.lastname: Seino
mesh_terms: D002675:Child, Preschool; D003116:Color; D003261:Contact Lenses; D003627:Data Interpretation, Statistical; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D005374:Filtration / Q000295:instrumentation; D006225:Hand; D006801:Humans; D008297:Male; D009039:Motion Perception / Q000502:physiology; D055095:Optics and Photonics; D010775:Photic Stimulation