title: Reactivation of oral-lingual herpes by chlorinated swimming pool water: a case report.
abstract: The authors describe the case of a highly stressed 36-year-old man who experienced ten or more painful episodes per year of recurrent oral-lingual herpes simplex virus 1, which were only partially responsive to acyclovir therapy for three years. A three-year diary of activities, personal stresses, concurrent infections, local trauma, and other possible psychogenic, somatogenic, and environmental events was used systematically to attempt to pair the stresses with the recurrent herpes episodes. Chlorinated swimming pool water seems to have been the triggering agent of the recurrent herpes simplex virus 1 episodes due to its temporal correlation and the greater than twenty-four-month asymptomatic period after the patient discontinued swimming in chlorinated water, but continued to swim in fresh and salt water, along with his normal pursuit of all other activities and habits.
authors.affiliation: Hematology Division of Clinical Chemistry, Crozer-Chester Medical Center, Upland, Pennsylvania 19013, USA.
authors.forename: M B
authors.initials: MB
authors.lastname: Detweiler
authors.forename: A
authors.initials: A
authors.lastname: Barelli
mesh_terms: D000328:Adult; D002713:Chlorine / Q000009:adverse effects*; D005618:Fresh Water; D018259:Herpesvirus 1, Human / Q000254:growth & development*; D006801:Humans; D008297:Male; D012008:Recurrence; D012623:Seawater; D013283:Stomatitis, Herpetic / Q000503:physiopathology*; D013312:Stress, Physiological / Q000503:physiopathology; D013551:Swimming Pools; D014060:Tongue Diseases / Q000503:physiopathology* / Q000821:virology*; D014775:Virus Activation; D014867:Water
chemical_list: D014867:Water; D002713:Chlorine