title: When one and one are not two.
abstract: Dimeric proteins can arise from monomers by the simple exchange of secondary structural elements or a wholesale swapping of domains. These results have implications for the construction of novel oligomeric molecules and illuminate how existing structures may have evolved.
authors.forename: R J
authors.initials: RJ
authors.lastname: Fletterick
authors.forename: J F
authors.initials: JF
authors.lastname: Bazan
mesh_terms: D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins