title: Budd-Chiari syndrome due to pacemaker-induced thrombosis.
abstract: We report a unique case of Budd-Chiari syndrome caused by pacemaker leads-induced thrombosis. A 34 year old female patient was subjected to a permanent pacemaker insertion because of refractory paroxysmal supraventricular tachycardia attacks related to Wolff-Parkinson-White syndrome. Three years later, another pacemaker was re-implanted because of its dislodgement. Four episodes of skin infections at the implantation site were noted thereafter. The patient developed symptoms of abdominal pain and ascites 5 years after the second pacemaker implantation. Ultrasonography and computerized tomography of the abdomen revealed hepatomegaly with ascites and dilated inferior vena cava. An echocardiogram displayed thrombus formation in the superior vena cava, the right atrium and the inlet of the inferior vena cava into the right atrium. Inferior and superior venacavogram confirmed the above findings. With the impression that Budd-Chiari syndrome was caused by pacemaker-induced thrombus, we removed the pacemaker first and thoracotomy with thrombectomy was then performed. The clinical symptoms resolved after the operation. To our knowledge, this is the first case reported in the literature and this observation supported the thrombosis theory for membranous obstruction of inferior vena cava.
authors.affiliation: Department of Medicine, Veterans General Hospital Taipei, Taiwan, ROC.
authors.forename: C L
authors.initials: CL
authors.lastname: Lu
authors.forename: S J
authors.initials: SJ
authors.lastname: Hwang
authors.forename: S A
authors.initials: SA
authors.lastname: Chen
authors.forename: T J
authors.initials: TJ
authors.lastname: Yu
authors.forename: Y H
authors.initials: YH
authors.lastname: Chou
authors.forename: S D
authors.initials: SD
authors.lastname: Lee
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D006502:Budd-Chiari Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D011860:Radiography, Abdominal; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000473:pathology