[Anaphylactic shock after lipid exchange chromatography in a patient with congenital IgA deficiency].
We report on a 59-year-old woman patient with selective IgA deficiency and familial hypercholesterinaemia. To lower elevated LDL levels in the patient's blood, immunoadsorption therapy with sheep-anti-human polyclonal antibodies coupled to sepharose columns was administered. During the procedure, the patient developed an anaphylactic shock requiring intensive care treatment. The patient's history revealed a fresh cell therapy with fetal sheep cells 10 years previously. Intracutaneous testing confirmed sensitization to sheep immunoglobulin, which was the most likely reason for the anaphylactic shock.
Enk
A H
AH
Hautklinik, Johannes Gutenberg Universität, Mainz.
Bauerschmitz
J
J
Knop
J
J
D000707:Anaphylaxis / Q000276:immunology*; D008078:Cholesterol, LDL / Q000097:blood*; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000276:immunology / Q000628:therapy*; D017098:IgA Deficiency / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood; D007163:Immunosorbent Techniques; D007428:Intradermal Tests; D008875:Middle Aged
D008078:Cholesterol, LDL; D007073:Immunoglobulin E