title: Cellular and extracellular components at nodes of Ranvier in rat white matter.
abstract: Rat CNS nodes of Ranvier were investigated by electron microscopy and immunohistochemistry. Nodes along thin callosal axons possess tiny node gaps containing few or no astrocytic processes. Nodes along thick spinal axons exhibit spatious node gaps containing relatively few irregularly arranged astrocytic processes. Antibodies against HNK-1, chondroitin sulfate, tenascin or NSP-4 do not label small nodes but stain large nodes. We conclude that rat CNS fibers do not exhibit a strict relation between nodal complexity and fiber size comparable to that found in rat PNS fibers.
authors.affiliation: Department of Cell Biology, Faculty of Health Sciences, University of Linköping, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Bjartmar
authors.forename: B
authors.initials: B
authors.lastname: Karlsson
authors.forename: C
authors.initials: C
authors.lastname: Hildebrand
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000032:analysis; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D001369:Axons / Q000737:chemistry / Q000648:ultrastructure*; D018959:CD57 Antigens; D015816:Cell Adhesion Molecules, Neuronal / Q000032:analysis; D002809:Chondroitin Sulfates / Q000032:analysis; D003337:Corpus Callosum / Q000737:chemistry / Q000648:ultrastructure; D018397:Equidae; D016326:Extracellular Matrix Proteins / Q000032:analysis; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D051379:Mice; D008854:Microscopy, Electron; D009419:Nerve Tissue Proteins / Q000032:analysis; D011817:Rabbits; D011901:Ranvier's Nodes / Q000737:chemistry / Q000648:ultrastructure*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000737:chemistry / Q000648:ultrastructure; D019063:Tenascin
chemical_list: D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D018959:CD57 Antigens; D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D005904:Glial Fibrillary Acidic Protein; D009419:Nerve Tissue Proteins; D019063:Tenascin; D002809:Chondroitin Sulfates