A recurrent translocation, t(3;11)(q21;q13), found in two distinct cases of acute myeloid leukemia.
We report two cases of acute myeloid leukemia (M1 and M5B subtypes) with a similar translocation, t(3;11)(q21;q13). We discuss the involvement of these breakpoints in acute leukemia and their putative clinical implications.
Cigudosa
J C
JC
Department of Genetics, University of Navarra, Pamplona, Spain.
Calasanz
M J
MJ
Odero
M D
MD
Marin
J
J
Bengoechea
E
E
Gullón
A
A
D000328:Adult; D002880:Chromosomes, Human, Pair 11; D002893:Chromosomes, Human, Pair 3; D005260:Female; D006801:Humans; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic