Endodermal sinus tumor arising from a dysgenetic gonad in a 46,XX female combined with müllerian agenesis.
The occurrence of neoplastic transformation in a dysgenetic gonad of a female with 46,XX karyotype is very rare. Moreover, to our knowledge, a case of endodermal sinus tumor arising from that setting combined with Müllerian agenesis has not been reported. This case suggests the possibility of development of cancer in a dysgenetic ovary of a female even with 46,XX or Müllerian agenesis.
Nam
J H
JH
Department of Obstetrics and Gynecology, Asan Medical Center, College of Medicine, University of Ulsan, Poongnap-dong, Songpa-gu, Seoul, Korea.
Chung
D G
DG
Kim
Y M
YM
Kim
Y T
YT
Mok
J E
JE
D000328:Adult; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000150:complications* / Q000473:pathology; D005260:Female; D006059:Gonadal Dysgenesis / Q000150:complications* / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D009095:Mullerian Ducts / Q000002:abnormalities*; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications* / Q000473:pathology; D000509:alpha-Fetoproteins / Q000378:metabolism
D000509:alpha-Fetoproteins