An evaluation of FASTMAP with emphasis on fine-mapping.
We present an evaluation of the FASTMAP method with special reference to the issue of fine-mapping, using both 'real-life' and constructed data, and demonstrate some of the shortcomings of the method. Since the advantages of FASTMAP in terms of savings in computer resources compared to LINK-MAP are enormous, further improvements of the FASTMAP method would be highly desirable.
Müller
B
B
Abteilung für pädiatrische Genetik der LMU, München, Deutschland.
Golla
A
A
D002874:Chromosome Mapping; D005260:Female; D006801:Humans; D008126:Lod Score; D008297:Male; D010375:Pedigree; D012984:Software