title: Fragile X boys: evolution of the mental age in childhood. Preliminary data on 10 prepubertal boys.
abstract: In this report we present data on the longitudinal evolution of the mental versus the chronological age in 10 fragile X boys diagnosed before the age of 6 years and compare these findings to the longitudinal evolution in children with Down syndrome (6 patients) and Williams syndrome (4 patients). The present findings suggest that the evolution of the velocity of development is more decreased in fra(x) boys compared to the two other groups.
authors.affiliation: Center for Human Genetics, University of Leuven, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Borghgraef
authors.forename: A
authors.initials: A
authors.lastname: Swillen
authors.forename: H
authors.initials: H
authors.lastname: Van den Berghe
authors.forename: J P
authors.initials: JP
authors.lastname: Fryns
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000235:genetics / Q000523:psychology; D005600:Fragile X Syndrome / Q000235:genetics* / Q000523:psychology; D006801:Humans; D007360:Intelligence / Q000235:genetics*; D008297:Male; D010641:Phenotype