title: Recombination in single and double heterozygotes for two partially overlapping inversions in chromosome 1 of the house mouse.
abstract: Recombination frequency, chiasmata and chromatid interference were studied by means of analysis of meiotic configurations in diakinesis and metaphase II in single and double heterozygotes for the partially overlapping inversions In(1)1Rk and In(1)12Rk in chromosome 1 of the house mouse. Recombination frequency in the inverted regions was decreased in single heterozygotes and increased in the double heterozygotes as compared to normal homozygotes. Chiasmata in the inverted regions in the double heterozygotes did not interfere with each other. A significant excess of 4-chromatid double exchanges in the inverted regions was detected in the double heterozygotes.
authors.affiliation: Institute of Cytology and Genetics, Novosibirsk, Russia.
authors.forename: I P
authors.initials: IP
authors.lastname: Gorlov
authors.forename: P M
authors.initials: PM
authors.lastname: Borodin
mesh_terms: D000818:Animals; D002842:Chromatids / Q000648:ultrastructure; D007446:Chromosome Inversion; D002875:Chromosomes / Q000235:genetics* / Q000648:ultrastructure; D003434:Crossing Over, Genetic; D005260:Female; D006579:Heterozygote; D008297:Male; D008540:Meiosis; D051379:Mice; D008815:Mice, Inbred Strains; D011995:Recombination, Genetic / Q000235:genetics*