title: [Effect of interferon on filtering blebs after trabeculectomy in rabbit eyes].
abstract: A study on the suppressive effect of interferon on the formation of filtering surgical scar was carried out. Trabeculectomy was performed on 6 rabbit eyes. 100,000 Units of interferon were subconjunctivally injected at the filtering bleb during the operation and on the 3rd and 7th post-operative day. The filtering blebs, filtering function and the scanning electron microscopic examinations of the surgical areas of the walls of the globes were observed. The results show that interferon can reduce the scar, improve filtering function and can be tried clinically.
authors.affiliation: Shanxi Eye Hospital, Taiyuan.
authors.forename: H
authors.initials: H
authors.lastname: Chi
authors.forename: X
authors.initials: X
authors.lastname: Fei
authors.forename: C
authors.initials: C
authors.lastname: Lai
mesh_terms: D000818:Animals; D002921:Cicatrix / Q000209:etiology / Q000628:therapy*; D005260:Female; D005901:Glaucoma / Q000601:surgery; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D011994:Recombinant Proteins; D012590:Sclera / Q000648:ultrastructure; D014130:Trabeculectomy / Q000009:adverse effects*
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins