Association between hepatitis C virus seroreactivity and HIV infection in non-intravenous drug abusing prostitutes.
Two hundred and ninety-four non-transfused prostitutes from Spain, who denied intravenous drug abuse, were tested for hepatitis C virus (HCV) antibodies. Seventeen (5.78%) of them were seropositive. Both in univariate and correspondence analyses, serological results for hepatitis C were associated with the HIV-1 serostatus (p < 0.001), number of sex partners (p < 0.05) and a history of genital ulcers (p < 0.05). In logistic regression analysis, hepatitis C seropositivity was associated only with HIV-1 infection (adjusted odds ratio = 13.6; 95% confidence interval = 3.3-55.2). These results show that hepatitis C seropositivity is associated with HIV-1 infection in female non-intravenous drug abusing prostitutes. These findings are also consistent with the hypothesis that HCV can be sexually transmitted with low efficiency.
Pineda
J A
JA
Department of Internal Medicine, Virgen del Rocío University Hospital, Seville, Spain.
Rivero
A
A
Rey
C
C
Hernández-Quero
J
J
Vergara
A
A
Muñoz
J
J
Aguado
I
I
Santos
J
J
Torronteras
R
R
Gallardo
J A
JA
D000328:Adult; D000704:Analysis of Variance; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology / Q000276:immunology*; D018937:Hepatitis C Antibodies / Q000032:analysis*; D006801:Humans; D016015:Logistic Models; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D011477:Sex Work / Q000706:statistics & numerical data; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000276:immunology*; D013030:Spain / Q000453:epidemiology; D015819:Substance Abuse, Intravenous
D018937:Hepatitis C Antibodies