Acetazolamide therapy evaluation in haemorrhagic stroke.
The influence of acetazolamide in patients with hemorrhagic stroke was assessed in 54 patients in comparison with the influence of other therapies in 68 patients included in a control group. Modified Rankin Scale and mortality rate were evaluated at three different moments: onset, 72 hours and control (3 weeks-one month from the onset). A better outcome was seen when acetazolamide was given. Mortality rate was significantly lower in the group of acetazolamide. This therapy may be safely used in haemorrhagic stroke, especially when hydrocephalus is associated.
Popa
G
G
Institute of Neurology and Psychiatry, G. Marinescu Hospital.
Amaireh
M
M
Dinu
M
M
Jipescu
I
I
Alaicescu
M
M
Stănescu
A
A
Nistorescu
A
A
D000086:Acetazolamide / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use*; D002543:Cerebral Hemorrhage / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D015170:Cerebrospinal Fluid Pressure / Q000187:drug effects; D002561:Cerebrovascular Disorders / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012383:Romania / Q000453:epidemiology
D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide