Primary T cell CD30-positive anaplastic large-cell lymphoma associated with adult-onset celiac disease and presenting with skin lesions.
We report the case of a 52-year-old woman with primary CD30+ anaplastic large-cell lymphoma of T cell phenotype with skin involvement, stage IVB, fulfilling almost all the clinical, histopathologic and immunophenotypic criteria for this disease, associated with adult-onset celiac disease. The diagnoses of malignancy and celiac disease were made during the same clinical episode. The clinical course of the patient has been extremely favorable and she is in complete remission, 15 months after finishing consolidation therapy.
Mantovani
G
G
Department of Medical Oncology, University of Cagliari, Italy.
Esu
S
S
Astara
G
G
Lampis
B
B
Macciò
A
A
Usai
P
P
Santa Cruz
G
G
Mura
E
E
Ferreli
A
A
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis*; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D016130:Immunophenotyping; D017730:Ki-1 Antigen / Q000032:analysis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D012074:Remission Induction; D012867:Skin / Q000473:pathology*; D013601:T-Lymphocytes / Q000276:immunology*
D017730:Ki-1 Antigen; D016179:Granulocyte Colony-Stimulating Factor