title: Cytotoxic lymphocytes. Two ways to kill target cells.
abstract: Of the two pathways implicated in target-cell damage by cytotoxic lymphocytes, secretory granule exocytosis seems to dominate in anti-viral immunity whereas the Fas pathway may regulate immune responses.
authors.affiliation: Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20814.
authors.forename: P A
authors.initials: PA
authors.lastname: Henkart
authors.forename: M V
authors.initials: MV
authors.lastname: Sitkovsky
mesh_terms: D000818:Animals; D000954:Antigens, Surface / Q000502:physiology*; D003594:Cytoplasmic Granules / Q000378:metabolism*; D003602:Cytotoxicity, Immunologic; D005089:Exocytosis; D006801:Humans; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*; D019014:fas Receptor
chemical_list: D000954:Antigens, Surface; D019014:fas Receptor