title: Microbial transformation of immunosuppressive compounds. IV. Hydroxylation and hemiketal formation of ascomycin (immunomycin) by Streptomyces sp. MA 6970 (ATCC No. 55281).
authors.affiliation: Merck Research Laboratory, Rahway, New Jersey 07065.
authors.forename: T S
authors.initials: TS
authors.lastname: Chen
authors.forename: B
authors.initials: B
authors.lastname: Petuch
authors.forename: R
authors.initials: R
authors.lastname: White
authors.forename: G
authors.initials: G
authors.lastname: Dezeny
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: B
authors.initials: B
authors.lastname: Arison
authors.forename: T
authors.initials: T
authors.lastname: Beattie
authors.forename: L
authors.initials: L
authors.lastname: Colwell
authors.forename: F
authors.initials: F
authors.lastname: Dumont
authors.forename: R
authors.initials: R
authors.lastname: Monaghan
mesh_terms: D001711:Biotransformation; D005285:Fermentation; D006900:Hydroxylation; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013302:Streptomyces / Q000378:metabolism*; D016559:Tacrolimus / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism
chemical_list: D007166:Immunosuppressive Agents; C058028:immunomycin; D016559:Tacrolimus