title: IgE antibodies reactive with silverfish, cockroach and chironomid are frequently found in mite-positive allergic patients.
abstract: Approximately 30% of the house dust mite allergic patients in The Netherlands have IgE antibodies reactive with silverfish, cockroach and/or chironomid. In allergic patients without IgE antibodies against Dermatophagoides pteronyssinus less than 5% have IgE antibodies reactive with these insects. By means of RAST inhibition studies it is shown that cross-reactivity exists between D. pteronyssinus and silverfish, cockroach or chironomid. This means that a positive RAST for silverfish, cockroach, chironomid or D. pteronyssinus cannot be taken as evidence for exposure.
authors.affiliation: Central Laboratory of The Netherlands Red Cross Blood Transfusion Service, University of Amsterdam.
authors.forename: A M
authors.initials: AM
authors.lastname: Witteman
authors.forename: S
authors.initials: S
authors.lastname: van den Oudenrijn
authors.forename: J
authors.initials: J
authors.lastname: van Leeuwen
authors.forename: J
authors.initials: J
authors.lastname: Akkerdaas
authors.forename: J S
authors.initials: JS
authors.lastname: van der Zee
authors.forename: R C
authors.initials: RC
authors.lastname: Aalberse
mesh_terms: D000818:Animals; D001249:Asthma / Q000276:immunology*; D002683:Chironomidae / Q000276:immunology*; D003058:Cockroaches / Q000276:immunology*; D003429:Cross Reactions; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology*; D007313:Insecta / Q000276:immunology*; D008925:Mites / Q000276:immunology*; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology*
chemical_list: D007073:Immunoglobulin E