title: Treatment of granuloma annulare with tranilast.
abstract: Three cases of granuloma annulare which did not exhibit a self-limited course were treated with tranilast at the dose of 300 mg/daily. The treatment resulted in the resolution of skin lesions within three months of administration. Although spontaneous resolution is often observed in granuloma annulare, tranilast may provide an alternative therapy for the treatment of cases resistant to spontaneous healing.
authors.affiliation: Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: A
authors.initials: A
authors.lastname: Ide
authors.forename: M
authors.initials: M
authors.lastname: Sugiura
authors.forename: S
authors.initials: S
authors.lastname: Kurihara
authors.forename: S
authors.initials: S
authors.lastname: Tajima
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001132:Arm; D001707:Biopsy, Needle; D005260:Female; D016460:Granuloma Annulare / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D006634:Histamine H1 Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013909:Thorax; D062367:ortho-Aminobenzoates / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D006634:Histamine H1 Antagonists; D062367:ortho-Aminobenzoates; C012293:tranilast