Interleukin-6: effects on tumor models in mice and on the cellular regulation of transcription factor IRF-1.
Revel
M
M
Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.
Katz
A
A
Eisenbach
L
L
Feldman
M
M
Haran-Ghera
N
N
Harroch
S
S
Chebath
J
J
D000818:Animals; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000378:metabolism / Q000502:physiology*; D004742:Enhancer Elements, Genetic; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D050856:Interferon Regulatory Factor-1; D050836:Interferon Regulatory Factor-2; D007372:Interferons / Q000494:pharmacology; D015850:Interleukin-6 / Q000494:pharmacology* / Q000627:therapeutic use; D015470:Leukemia, Myeloid, Acute / Q000473:pathology / Q000503:physiopathology; D008546:Melanoma, Experimental / Q000503:physiopathology; D051379:Mice; D008810:Mice, Inbred C57BL; D008969:Molecular Sequence Data; D009362:Neoplasm Metastasis; D010750:Phosphoproteins / Q000502:physiology*; D012045:Regulatory Sequences, Nucleic Acid; D012097:Repressor Proteins; D014157:Transcription Factors
D004268:DNA-Binding Proteins; D050856:Interferon Regulatory Factor-1; D050836:Interferon Regulatory Factor-2; D015850:Interleukin-6; C494258:Irf1 protein, mouse; C494230:Irf2 protein, mouse; D010750:Phosphoproteins; D012097:Repressor Proteins; D014157:Transcription Factors; D007372:Interferons