title: Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
abstract: Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: B
authors.initials: B
authors.lastname: Ramakrishnan
authors.forename: M
authors.initials: M
authors.lastname: Sundaralingam
mesh_terms: D000998:Antiviral Agents; D003461:Crystallography; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D004214:Distamycins / Q000737:chemistry* / Q000378:metabolism; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000998:Antiviral Agents; D004214:Distamycins; D012313:RNA; C030000:stallimycin; D004247:DNA