title: Perforated acute appendicitis in a patient with AIDS/HIV infection: report of a case.
abstract: We report herein the case of a 40-year-old man with AIDS who was admitted to hospital with severe abdominal pain, fever, and chills. He underwent an emergency laparotomy which revealed a perforated appendix with suppurative peritonitis. An appendectomy with peritoneal drainage was carried out, but the postoperative course was complicated by fever without leukocytosis; however, he gradually improved following treatment with intravenous antibiotics, granulocyte colony-stimulating factor (G-CSF) and immunoglobulins, and made a complete recovery. His postoperative course demonstrates the effectiveness of this treatment regimen for patients with AIDS complicated by infection without an increase in the white blood cell count (WBC).
authors.affiliation: First Department of Surgery, Nagoya City University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Mohri
authors.forename: Y
authors.initials: Y
authors.lastname: Akamo
authors.forename: H
authors.initials: H
authors.lastname: Takeyama
authors.forename: M
authors.initials: M
authors.lastname: Mizokami
authors.forename: H
authors.initials: H
authors.lastname: Yuasa
authors.forename: I
authors.initials: I
authors.lastname: Mizuno
authors.forename: N
authors.initials: N
authors.lastname: Shinagawa
authors.forename: T
authors.initials: T
authors.lastname: Manabe
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000208:Acute Disease; D000328:Adult; D001062:Appendectomy; D001064:Appendicitis / Q000150:complications / Q000382:microbiology* / Q000601:surgery; D015377:Cilastatin / Q000627:therapeutic use; D000077728:Cilastatin, Imipenem Drug Combination; D004338:Drug Combinations; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000150:complications*; D005335:Fever of Unknown Origin / Q000628:therapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D007116:Immunization, Passive; D007416:Intestinal Perforation / Q000150:complications* / Q000601:surgery; D008297:Male; D011183:Postoperative Complications / Q000628:therapy; D012422:Rupture, Spontaneous
chemical_list: D004338:Drug Combinations; D015377:Cilastatin; D016179:Granulocyte Colony-Stimulating Factor; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination