title: History of medical radionuclide production.
abstract: Radionuclide production for medical use originally was incidental to isotope discoveries by physicists and chemists. Once the available radionuclides were identified they were evaluated for potential medical use. Hevesy first used 32P in 1935 to study phosphorous metabolism in rats. Since that time, the development of cyclotrons, linear accelerators, and nuclear reactors have produced hundreds of radionuclides for potential medical use. The history of medical radionuclide production represents an evolutionary, interdisciplinary development of applied nuclear technology. Today the technology is represented by a mature industry and provides medical benefits to millions of patients annually.
authors.affiliation: Neely Nuclear Research Center, Georgia Institute of Technology, Atlanta 30332-042, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Ice
mesh_terms: D000818:Animals; D017357:Cyclotrons; D049673:History, 20th Century; D006801:Humans; D009683:Nuclear Medicine / Q000266:history*; D010315:Particle Accelerators; D011868:Radioisotopes / Q000266:history* / Q000627:therapeutic use
chemical_list: D011868:Radioisotopes