[The lateralized effects of the melanostatin analog alaptide in rats raised in isolation and in a community].
Effects of alaptide on self-stimulation of the lateral hypothalamus, rotation behaviour and learning ability were studied in rats growing either in social adaptation or in groups. The effects on self-stimulation were opposite in these rats. Alaptide facilitated the learning process in grouped rats and potentiated the indirect dophamine-mimetic action of amphetamine in isolated rats.
Lebedev
A A
AA
Shabanov
P D
PD
Chepurnova
N E
NE
Paskhali
E
E
Krejcí
I
I
Kasafírek
E
E
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D007839:Functional Laterality / Q000187:drug effects* / Q000502:physiology; D007026:Hypothalamic Area, Lateral / Q000187:drug effects / Q000502:physiology; D009075:MSH Release-Inhibiting Hormone / Q000031:analogs & derivatives*; D008297:Male; D009479:Neuropeptides / Q000494:pharmacology*; D010456:Peptides, Cyclic / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012399:Rotation; D012653:Self Stimulation / Q000187:drug effects / Q000502:physiology; D012919:Social Behavior; D012934:Social Isolation; D013239:Stereotyped Behavior / Q000187:drug effects / Q000502:physiology
D009479:Neuropeptides; D010456:Peptides, Cyclic; C049178:cyclo(alanine-(1-amino-1-cyclopentane)carbonyl); D009075:MSH Release-Inhibiting Hormone; D000661:Amphetamine