title: Signal transduction through IL-6 receptor: involvement of multiple protein kinases, stat factors, and a novel H7-sensitive pathway.
authors.affiliation: Division of Molecular Oncology, Osaka University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: T
authors.initials: T
authors.lastname: Matsuda
authors.forename: Y
authors.initials: Y
authors.lastname: Fujitani
authors.forename: H
authors.initials: H
authors.lastname: Kojima
authors.forename: Y
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: K
authors.initials: K
authors.lastname: Nakae
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: T
authors.initials: T
authors.lastname: Hirano
mesh_terms: D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D000818:Animals; D015703:Antigens, CD; D001483:Base Sequence; D003001:Cloning, Molecular; D050822:Cytokine Receptor gp130; D004268:DNA-Binding Proteins / Q000502:physiology; D016758:Genes, jun; D006801:Humans; D007546:Isoquinolines / Q000494:pharmacology; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D008562:Membrane Glycoproteins / Q000502:physiology*; D051379:Mice; D008969:Molecular Sequence Data; D019000:Phosphotyrosine; D010879:Piperazines / Q000494:pharmacology; D011401:Promoter Regions, Genetic; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases / Q000502:physiology*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D011518:Proto-Oncogene Proteins; D016755:Proto-Oncogene Proteins c-jun / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras) / Q000502:physiology; D018123:Receptors, Interleukin / Q000502:physiology*; D019947:Receptors, Interleukin-6; D015398:Signal Transduction; D015534:Trans-Activators; D014157:Transcription Factors / Q000502:physiology; D014443:Tyrosine / Q000031:analogs & derivatives / Q000378:metabolism; D000511:alpha-Macroglobulins / Q000235:genetics
chemical_list: D015703:Antigens, CD; D004268:DNA-Binding Proteins; C494199:IL6ST protein, human; C494200:Il6st protein, mouse; D007546:Isoquinolines; D008562:Membrane Glycoproteins; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D011518:Proto-Oncogene Proteins; D016755:Proto-Oncogene Proteins c-jun; D018123:Receptors, Interleukin; D019947:Receptors, Interleukin-6; D015534:Trans-Activators; D014157:Transcription Factors; D000511:alpha-Macroglobulins; D050822:Cytokine Receptor gp130; D019000:Phosphotyrosine; D014443:Tyrosine; D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D011494:Protein Kinases; D011505:Protein-Tyrosine Kinases; C507904:JAK1 protein, human; C507924:JAK2 protein, human; C507905:Jak1 protein, mouse; C507926:Jak2 protein, mouse; D053613:Janus Kinase 1; D053614:Janus Kinase 2; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras)