title: Anomalous origin of the left coronary artery from the pulmonary artery in adults.
abstract: Between March 1986 and December 1994, four adult patients underwent surgery for anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) at the German Heart Institute Berlin. The patients, aged 27, 35, 54, and 60, were all females. ALCAPA was diagnosed 3 to 8 months before surgery. The patients presented with cardiac murmur (two patients), abnormal ECG pattern (two patients), arrhythmia (one patient), and acute myocardial infarction (one patient). During surgery a two coronary system was established either by Takeuchi operation (one patient), interruption of the anomalous vessel and aortocoronary saphenous vein bypass (two patients), or internal mammary artery bypass (one patient). There were no postoperative deaths, however, one patient had to be reoperated because of a recurrent shunt. Clinical improvement was observed in all four patients with disappearance of fatigue, angina, dyspnea, and ischemic ECG changes. Despite having this long-standing congenital heart defect, adult and elderly patients with ALCAPA may benefit from surgical intervention to establish a two coronary system.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, German Heart Institute Berlin, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Alexi-Meskishvili
authors.forename: F
authors.initials: F
authors.lastname: Berger
authors.forename: Y
authors.initials: Y
authors.lastname: Weng
authors.forename: P E
authors.initials: PE
authors.lastname: Lange
authors.forename: R
authors.initials: R
authors.lastname: Hetzer
mesh_terms: D000328:Adult; D003330:Coronary Vessel Anomalies / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009204:Myocardial Revascularization; D011651:Pulmonary Artery / Q000002:abnormalities*; D016896:Treatment Outcome