Coronary sinus retroperfusion combined with intraaortic balloon pumping to perfuse the acutely ischemic myocardium.
This study was planned to show the effect of retroperfusion and intraaortic balloon pumping (IABP) on myocardial hemodynamic recovery. Twelve dogs entered this study. Half of them received IABP and coronary sinus retroperfusion (CSPR) combination (Group II) and the remaining received IABP alone (Group I). Left anterior descending artery was occluded for a period of three hours. 15 minutes after occlusion IABP and IABP + CSRP were initiated. The average cardiac output was 1.41 +/- 0.18 L/min in the group I and 1.72 +/- 0.24 L/min in the group II (p < 0.03) after 3 hours of occlusion. Mean arterial pressure was 82.1 +/- 4.8 mmHg in the group I and 89.7 +/- 2.6 mmHg in the group II (p < 0.03). On the basis of this study it was concluded that CSRP + IABP could be an alternative treatment to IABP alone during the acutely developing ischemia.
Katircioğlu
S F
SF
Cardiovascular Surgery Clinic, Türkiye Yüksek Ihtisas Hospital, Ankara.
Küçükaksu
D S
DS
Gökçe
P
P
Ozgenci
E
E
Tasdemir
O
O
Bayazit
K
K
D000208:Acute Disease; D000818:Animals; D003131:Combined Modality Therapy; D004285:Dogs; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D007423:Intra-Aortic Balloon Pumping; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000628:therapy*; D015425:Myocardial Reperfusion; D013997:Time Factors