title: Stability of FK 506 in whole blood samples.
abstract: The effect of storage time and temperature on the stability of FK 506 in patient blood samples and quality control samples was assessed with the Abbott IMx microparticle enzyme immunoassay. Blood FK 506 concentrations measured at days 0, 2, 3, 4, 7, and 14 were stable at room (22 degrees C), refrigerator (4 degrees C), and freezer (-70 degrees C) temperatures for the 2-week study period. Patient samples stored at -70 degrees C for almost 1 year and then reanalyzed for FK 506 were also found to be stable.
authors.affiliation: Department of Medicine, University of Western Ontario, Canada.
authors.forename: D J
authors.initials: DJ
authors.lastname: Freeman
authors.forename: M
authors.initials: M
authors.lastname: Stawecki
authors.forename: B
authors.initials: B
authors.lastname: Howson
mesh_terms: D001800:Blood Specimen Collection; D004355:Drug Stability; D006801:Humans; D016559:Tacrolimus / Q000097:blood / Q000737:chemistry*; D013696:Temperature
chemical_list: D016559:Tacrolimus