Antigens recognized on human tumors by cytolytic T lymphocytes: towards vaccination?
It has been known for many years that cytolytic T lymphocytes that specifically recognize the tumor cells of the same patient can be derived from the blood of melanoma patients. Several of the antigens recognized by these antitumor T lymphocytes have now been completely identified. Some of them are sufficiently tumor-specific to envision their use as antitumor vaccines in selected cancer patients.
Coulie
P G
PG
Ludwig Institute for Cancer Research, Brussels Branch, Belgium.
D000951:Antigens, Neoplasm / Q000235:genetics; D001324:Autoantigens; D006801:Humans; D007167:Immunotherapy; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*; D009857:Oncogenes; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014611:Vaccination
D000951:Antigens, Neoplasm; D001324:Autoantigens