title: Activation of xenobiotics into free radicals by prostaglandin-H-synthase and by rat liver microsomes.
authors.affiliation: Department of Preclinical and Clinical Pharmacology, Florence University, Italy.
authors.forename: P F
authors.initials: PF
authors.lastname: Mannaioni
authors.forename: M G
authors.initials: MG
authors.lastname: Di Bello
authors.forename: S
authors.initials: S
authors.lastname: Raspanti
authors.forename: L
authors.initials: L
authors.lastname: Mugnai
authors.forename: V
authors.initials: V
authors.lastname: Romano
authors.forename: E
authors.initials: E
authors.lastname: Masini
mesh_terms: D000818:Animals; D003042:Cocaine / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism; D006636:Histamine Release / Q000187:drug effects; D008315:Malondialdehyde / Q000378:metabolism*; D008407:Mast Cells / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D008691:Methadone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000378:metabolism*; D009020:Morphine / Q000494:pharmacology; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D015262:Xenobiotics / Q000378:metabolism*
chemical_list: D005609:Free Radicals; D015262:Xenobiotics; D008315:Malondialdehyde; D009020:Morphine; D011451:Prostaglandin-Endoperoxide Synthases; D003042:Cocaine; D008691:Methadone