title: Role of AgNOR in diagnosis of thyroid follicular neoplasms on fine-needle aspiration smears.
abstract: This is a retrospective study to examine the role of AgNOR in differentiating thyroid follicular carcinoma and adenoma preoperatively on fine-needle aspiration (FNA) smears. Nineteen histopathology-proven cases of follicular adenoma and carcinoma were selected for this study. May-Grünwald-Giemsa-stained smears were destined and AgNOR staining technique was employed. Significant differences of AgNOR values were observed among follicular carcinoma versus adenoma (P < .05) and follicular carcinoma versus control cases (P < .01). Thereby the AgNOR technique may have some role in differentiating between benign and malignant follicular neoplasms of thyroid.
authors.affiliation: Department of Pathology and Cytology, PGIMER, Chandigarh, India.
authors.forename: T
authors.initials: T
authors.lastname: Karmakar
authors.forename: P
authors.initials: P
authors.lastname: Dey
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis* / Q000648:ultrastructure; D000236:Adenoma / Q000175:diagnosis* / Q000648:ultrastructure; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000648:ultrastructure; D003937:Diagnosis, Differential; D006801:Humans; D009697:Nucleolus Organizer Region; D011397:Promegestone / Q000032:analysis; D013194:Staining and Labeling; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure
chemical_list: D011397:Promegestone