Microvillus assembly. Not actin alone.
Transfection studies provide supporting evidence for the proposed role of villin and fimbrin in bundling the core actin filaments of microvilli.
Fath
K R
KR
Department of Biological Sciences, University of Pittsburgh, Pennsylvania 15260, USA.
Burgess
D R
DR
D008841:Actin Cytoskeleton / Q000378:metabolism*; D000199:Actins / Q000378:metabolism*; D000818:Animals; D002277:Carcinoma / Q000473:pathology; D002352:Carrier Proteins / Q000502:physiology*; D002460:Cell Line; D002645:Chickens; D003110:Colonic Neoplasms / Q000473:pathology; D003598:Cytoskeletal Proteins; D006801:Humans; D007668:Kidney; D008562:Membrane Glycoproteins / Q000502:physiology*; D008840:Microfilament Proteins / Q000502:physiology*; D008871:Microvilli / Q000378:metabolism* / Q000648:ultrastructure; D010750:Phosphoproteins / Q000502:physiology; D013552:Swine; D014407:Tumor Cells, Cultured; D000099149:Ezrin
D000199:Actins; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; D008562:Membrane Glycoproteins; D008840:Microfilament Proteins; D010750:Phosphoproteins; D000099149:Ezrin; C026742:plastin; C026615:villin