title: Non-intercalative and sequence-selective interaction of nitropyrene/acridine-skeleton with nucleotides: application of the dextran-coupling method.
abstract: Water-insoluble typical intercalators, acridine and pyrene, were converted to water-soluble species, Dex-Pyr and Dex-Acr, respectively, by coupling with dextran polymer. By the use of these dextran-coupled intercalators, interactions of acridine- and pyrene-skeletones with various nucleotides in aqueous solutions were analyzed.
authors.affiliation: Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shichita
authors.forename: R
authors.initials: R
authors.lastname: Shimazawa
authors.forename: O
authors.initials: O
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Mizoguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: S
authors.initials: S
authors.lastname: Iwasaki
mesh_terms: D000166:Acridines / Q000737:chemistry*; D001483:Base Sequence; D003911:Dextrans / Q000737:chemistry*; D007364:Intercalating Agents / Q000737:chemistry*; D008969:Molecular Sequence Data; D009711:Nucleotides / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D014462:Ultrafiltration
chemical_list: D000166:Acridines; D003911:Dextrans; D007364:Intercalating Agents; D009711:Nucleotides; D011721:Pyrenes; C032668:1-nitropyrene