title: [The clinical study of local treatment of ocular malignant tumors with IL-2 LAK cells].
abstract: The authors reported the method of treatment of ocular malignant tumors at early and middle stages with local injections of self lymphokine-activated killing (LAK) cells which were induced by gamma IL-2 in vitro. Satisfactory therapeutic results were obtained. Among the 25 cases of ocular malignant tumors, 10 cases were treated only with IL-2 LAK cells, nine of them got complete regression (CR) and one got partial regression (PR); the other 15 cases were treated with operation and IL-2 LAK cells and they all obtained complete remission. In the follow-up, except the contact of 1 case with PR was lost, all the other 24 cases did not relapse after 1-5 years of observation. The above results show that the treatment of malignant tumors with local injection of self IL-2 LAK cells is a very effective immunotherapy.
authors.affiliation: Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi'an.
authors.forename: L
authors.initials: L
authors.lastname: Yang
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: G
authors.initials: G
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016219:Immunotherapy, Adoptive; D007376:Interleukin-2 / Q000627:therapeutic use*; D015979:Killer Cells, Lymphokine-Activated / Q000637:transplantation*; D008297:Male; D008875:Middle Aged
chemical_list: D007376:Interleukin-2