Analyses of monoclonal antibodies reactive with porcine CD6.
Amongst the monoclonal antibodies (mAbs) submitted to the first porcine CD workshop, two mAbs (workshop numbers 055 and 120) could be identified to recognize the porcine CD6 analogue. Both mAbs seemed to be highly T-cell specific and showed neither reactivity with cells of the myeloic lineage nor with B lymphocytes. The observed molecular mass of the antigen precipitated by mAb 120 of 110 kDa confirmed this classification. Without molecular analyses of the antigen recognized by mAb 055, but similar staining pattern in FCM compared with 120, mAb 055 was allocated to the wCD6 subcluster.
Saalmüller
A
A
Federal Research Centre for Virus Diseases of Animals, Tübingen, Germany.
Aasted
B
B
Canals
A
A
Dominguez
J
J
Goldman
T
T
Lunney
J K
JK
Maurer
S
S
Pauly
T
T
Pescovitz
M D
MD
Pospisil
R
R
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000918:Antibody Specificity / Q000276:immunology; D015703:Antigens, CD / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D000939:Epitopes / Q000276:immunology; D005434:Flow Cytometry / Q000662:veterinary; D013552:Swine / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; C062279:CD6 antigen; D000939:Epitopes