Role of eosinophils in childhood asthma inflammation.
The serum levels of eosinophil cationic protein (ECP) are raised in asthmatic children and indicate an eosinophil involving inflammatory process of the lungs. ECP measurements in serum may be used to monitor the severity of asthma in children and the efficacy of treatment with inhaled corticosteroids as well as to monitor allergen exposure. From these rather indirect studies we suspect that the inflammatory process in childhood asthma is the same as that seen in adults and involves the eosinophils.
Venge
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Asthma Research Centre, University of Uppsala, University Hospital, Sweden.
D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D001798:Blood Proteins / Q000032:analysis*; D001992:Bronchoalveolar Lavage Fluid; D002648:Child; D002675:Child, Preschool; D047091:Eosinophil Granule Proteins; D006801:Humans; D018836:Inflammation Mediators / Q000032:analysis*; D008168:Lung / Q000503:physiopathology; D012260:Ribonucleases; D012720:Severity of Illness Index
D015415:Biomarkers; D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D018836:Inflammation Mediators; D012260:Ribonucleases