title: Treatment of cluster headache and its variants.
abstract: In cluster headache, subcutaneous administration of sumatriptan has been established as an efficient, safe and well tolerated treatment for acute attacks. For prophylactic treatment, capsaicin (intranasal administration) and leuprolide (a synthetic slow-release gonadotrophin-releasing hormone) seem to be promising. Hyperbaric oxygen therapy seems to be effective in acute attacks, but it is of interest mostly because of its apparent interruption of the cluster period in some patients. In chronic paroxysmal hemicrania, which clinically resembles cluster headache, indomethacin is still necessary for diagnosis, and it is the treatment of choice in most patients. However, because of its potential side effects, alternative treatments should be sought.
authors.affiliation: Department of Neurology, Trondheim University Hospital, Norway.
authors.forename: L J
authors.initials: LJ
authors.lastname: Stovner
authors.forename: O
authors.initials: O
authors.lastname: Sjaastad
mesh_terms: D003027:Cluster Headache / Q000209:etiology / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007279:Injections, Subcutaneous; D008881:Migraine Disorders / Q000209:etiology / Q000628:therapy*; D017366:Serotonin Receptor Agonists / Q000008:administration & dosage / Q000009:adverse effects; D018170:Sumatriptan / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D017366:Serotonin Receptor Agonists; D018170:Sumatriptan