Tamoxifen is a Na(+)-antagonistic inhibitor of Na+/K(+)-transporting ATPase from tumour and normal cells.
Repke
K R
KR
Max-Delbrück Centre for Molecular Medicine, Berlin-Buch, Germany.
Matthes
E
E
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors; D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology* / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects / Q000201:enzymology*; D007700:Kinetics; D051379:Mice; D009206:Myocardium / Q000201:enzymology*; D012964:Sodium / Q000378:metabolism / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors*; D013629:Tamoxifen / Q000737:chemistry / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D013629:Tamoxifen; D000255:Adenosine Triphosphate; D012964:Sodium; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000254:Sodium-Potassium-Exchanging ATPase