title: Trisomy 14: a recurring cytogenetic abnormality associated with myeloid disorders.
abstract: Trisomy 14 as single karyotype aberration was detected in three patients, two with acute myeloblastic leukemia, AML-M2 type, and one with aplastic anemia. These new observations and the 28 previously reported cases confirm that trisomy 14 is a primary non random change, mostly confined to myeloid disorders.
authors.affiliation: Unité INSERM U301, Institut de Génétique Moléculaire, Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Poirel
authors.forename: P
authors.initials: P
authors.lastname: Jonveaux
authors.forename: M T
authors.initials: MT
authors.lastname: Daniel
authors.forename: R
authors.initials: R
authors.lastname: Berger
mesh_terms: D000328:Adult; D000368:Aged; D000741:Anemia, Aplastic / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D001855:Bone Marrow Diseases / Q000235:genetics; D002883:Chromosomes, Human, Pair 14; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics; D014314:Trisomy