Cation-induced efflux of calcium from the mitochondria of Hymenolepis diminuta.
We have previously reported that Ca2+ influx into the mitochondria of Hymenolepis diminuta, a rat intestinal cestode, takes place through an electrophoretic uniport system. Sodium and lithium were found to induce efflux of 45Ca2+ from the mitochondria of H. diminuta. The two cations induced the efflux in a hyperbolic and linear fashion, respectively. The efflux as well as an exchange of external Ca2+ with internal 45Ca2+ was inhibited by lanthanum. The type of Ca2+ transport system in the cestode organelle has been discussed and compared with that of the host (mammalian) counterpart.
Wani
J H
JH
Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
Siddiqui
A
A
Srivastava
V M
VM
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002122:Calcium Chloride / Q000378:metabolism; D002412:Cations / Q000378:metabolism; D006926:Hymenolepis; D008094:Lithium / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012964:Sodium / Q000378:metabolism
D002412:Cations; D008094:Lithium; D012964:Sodium; D002122:Calcium Chloride; D002118:Calcium