title: The prediction of clinical outcome from transurethral microwave thermotherapy by pressure-flow analysis: a European multicenter study.
abstract: A total of 100 patients treated with a single session of microwave thermotherapy at 4 European centers was stratified according to 2 different types of obstruction (constrictive and compressive) and compared to clinical outcome at 6 months. Patients had a Madsen-Iversen score of 8 or more, maximum flow rate of 15 ml. per second or less and residual urine volume of 300 ml. or less at entry. The change in Madsen-Iversen score was the same in the 2 groups. Maximum flow rate increased from 8.71 +/- 2.62 to 14.73 +/- 4.04 ml. per second in the constrictive group, and from 8.54 +/- 2.26 to 10.41 +/- 4.52 in the compressive group (p < or = 0.0001). Residual urine decreased from 96.00 +/- 72.85 to 40.34 +/- 56.33 ml. in the constrictive group and from 109.86 +/- 67.09 to 84.65 +/- 81.45 ml. in the compressive group (p < or = 0.0001). Success, as defined by an increase of 50% or more in maximum flow rate and Madsen-Iversen score, was noted in 68% of the constrictive but only 15% of the compressive groups (p < or = 0.0001 chi-square test for trend). Selection by pressure-flow criteria for patients being considered for thermotherapy should improve the overall clinical results.
authors.affiliation: Department of Surgery, L'Aquila University School of Medicine, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tubaro
authors.forename: S S
authors.initials: SS
authors.lastname: Carter
authors.forename: J
authors.initials: J
authors.lastname: de la Rosette
authors.forename: K
authors.initials: K
authors.lastname: Höfner
authors.forename: A
authors.initials: A
authors.lastname: Trucchi
authors.forename: C
authors.initials: C
authors.lastname: Ogden
authors.forename: L
authors.initials: L
authors.lastname: Miano
authors.forename: M
authors.initials: M
authors.lastname: Valenti
authors.forename: U
authors.initials: U
authors.lastname: Jonas
authors.forename: F
authors.initials: F
authors.lastname: Debruyne
mesh_terms: D003972:Diathermy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011470:Prostatic Hyperplasia / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014524:Urethral Obstruction / Q000209:etiology / Q000628:therapy; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000628:therapy; D014563:Urodynamics / Q000502:physiology