Clinical lessons from an experimental model of ARDS.
The oleic acid (OA) lung injury model is one of the most common laboratory methods for studying the acute respiratory distress syndrome (ARDS) in experimental animals. Many features of the model mimic the pathophysiology of ARDS in humans, despite obvious differences in pathogenesis. Thus, the OA lung injury model has been used extensively to study the consequence of lung injury and to evaluate potential new treatment strategies.
Schuster
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DP
Department of Internal Medicine, Washington University Medical School, St. Louis, Missouri 63110, USA.
D000818:Animals; D004195:Disease Models, Animal; D008168:Lung / Q000187:drug effects / Q000473:pathology; D019301:Oleic Acid; D009829:Oleic Acids / Q000494:pharmacology*; D012128:Respiratory Distress Syndrome / Q000473:pathology / Q000503:physiopathology
D009829:Oleic Acids; D019301:Oleic Acid