Simple detection of the inter-alpha-trypsin-inhibitor (ITI) polymorphism by isoelectric focusing with direct immunofixation.
The inter-alpha-trypsin inhibitor (ITI) polymorphism was analysed in a German population, using polyacrylamide gel isoelectric focusing with subsequent direct immunofixation with monospecific ITI antisera. Gene frequencies of ITI*1, ITI*2, ITI*3, and ITI*4 were calculated to be 0.6150, 0.3753, 0.0078 and 0.0019, respectively. In our study the allele ITI*4 is described for the first time in a German population.
Martin
A
A
Institute for Forensic Medicine, Faculty of Medicine, (Charité), Humboldt University, Berlin, Germany.
Correns
A
A
Otremba
P
P
Geserick
G
G
D000483:Alleles; D000510:Alpha-Globulins / Q000235:genetics*; D005787:Gene Frequency; D005858:Germany; D006801:Humans; D007106:Immune Sera; D007525:Isoelectric Focusing / Q000379:methods*; D010641:Phenotype; D011110:Polymorphism, Genetic
D000510:Alpha-Globulins; D007106:Immune Sera; C011877:inter-alpha-inhibitor