Invited review: intrinsic radiosensitivity as a predictor of patient response to radiotherapy.
This article reviews the available literature on intrinsic radiosensitivity as a predictor of patient response to radiotherapy. Results have been summarised for tumour, fibroblast and lymphocyte radiosensitivity where results have been correlated with clinical data. Suggestions are made for the possible way forward in this area of radiobiology.
West
C M
CM
Department of Experimental Radiation Oncology, Paterson Institute for Cancer Research, Christie Hospital, Manchester, UK.
D005347:Fibroblasts / Q000528:radiation effects; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects; D009369:Neoplasms / Q000532:radiotherapy*; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage; D016896:Treatment Outcome; D014407:Tumor Cells, Cultured / Q000528:radiation effects; D014410:Tumor Stem Cell Assay