Interleukin-8 production by human mesothelial cells after direct stimulation with staphylococci.
Mesothelial cells (MC) are able to produce interleukin-8 (IL-8) after stimulation with IL-1 beta or tumor necrosis factor alpha. The aim of our study was to investigate whether MC are able to produce IL-8 after direct stimulation with clinically relevant bacteria. We observed a significant IL-8 response by the MC which were directly stimulated with viable staphylococci.
Visser
C E
CE
Department of Cell Biology & Immunology, Faculty of Medicine, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands.
Steenbergen
J J
JJ
Betjes
M G
MG
Meijer
S
S
Arisz
L
L
Hoefsmit
E C
EC
Krediet
R T
RT
Beelen
R H
RH
D002478:Cells, Cultured; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology; D016209:Interleukin-8 / Q000096:biosynthesis*; D013210:Staphylococcus / Q000502:physiology*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D007375:Interleukin-1; D016209:Interleukin-8; D014409:Tumor Necrosis Factor-alpha