Histopathological changes induced by chronic nonlethal levels of elsan, mercury, and ammonia in the small intestine of Channa punctatus (Bloch).
Histopathological changes in the intestine of Channa punctatus induced by chronic nonlethal levels of Elsan (211 ppb), mercury (16.7 ppb), and ammonia (15.64 ppm) were studied at 7-day intervals for 90 days and the data were presented only for days (7, 28, 63, and 90) when the most conspicuous changes were noted after treatment. In the earlier phases of Elsan treatment (7 and 28 days) overall destruction of the structure of villus and other layers was prominent. Histopathology of the intestine of C. punctatus, after 63-day Elsan exposure, could be described as collapsed villi with the tips merged with each other to give a flattened appearance. Ninety-day Elsan exposure demonstrated severe damage in the longitudinal muscle layer. After 7-day mercury treatment a high degree of necrosis was indicated by submucosal area, whereas 28-day mercury treatment revealed collapsed villi due to necrotic mucosal cells and goblet cells. Mercury treatment for 63 days caused disarray of all the layers, but some improvement of villus organization was noted in fish treated with mercury for 90 days. Seven-day exposure to ammonia deteriorated the normal structure of the villus, whereas in 28-day ammonia exposure, lesions were predominant in the submucosal layers. Sixty-three-day ammonia treatment demonstrated an effect similar to that produced by Elsan, associated with a more complete destruction of all the layers. Fishes under ammonia treatment for 90 days demonstrated extensive damage to the mucosal folds. The major changes in thickness of different layers of the intestine were also evaluated.(ABSTRACT TRUNCATED AT 250 WORDS)
Banerjee
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S
Department of Zoology, School of Life Science, Visva-Bharati University, Santiniketan, West Bengal, India.
Bhattacharya
S
S
D000641:Ammonia / Q000633:toxicity*; D000818:Animals; D005399:Fishes; D007306:Insecticides / Q000633:toxicity; D007421:Intestine, Small / Q000187:drug effects* / Q000473:pathology; D008628:Mercury / Q000633:toxicity*; D009946:Organothiophosphorus Compounds / Q000633:toxicity*; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D007306:Insecticides; D009946:Organothiophosphorus Compounds; D014874:Water Pollutants, Chemical; D000641:Ammonia; D008628:Mercury; C008838:phenthoate