title: The poisoned patient. Toxicologic emergencies.
abstract: Local anesthetics with and without vasoconstrictors, analgesics, antibiotics, and antianxiety medications are used routinely in dentistry. Most agents used in the dental office have a safe therapeutic dose range between effective and toxic so that the potential for adverse reactions is easily ignored. This article discusses toxicity, allergy, idiosyncrasy, drug interactions, local anesthesia, and the use of recreational drugs and alcohol.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
authors.forename: L H
authors.initials: LH
authors.lastname: Norris
authors.forename: M B
authors.initials: MB
authors.lastname: Papageorge
mesh_terms: D000700:Analgesics / Q000009:adverse effects / Q000506:poisoning; D000779:Anesthetics, Local / Q000009:adverse effects / Q000506:poisoning; D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000506:poisoning; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000506:poisoning; D003729:Dental Care; D004342:Drug Hypersensitivity / Q000628:therapy; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D004630:Emergencies; D000431:Ethanol / Q000506:poisoning; D006801:Humans; D011041:Poisoning / Q000628:therapy*; D019966:Substance-Related Disorders
chemical_list: D000700:Analgesics; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D000900:Anti-Bacterial Agents; D000431:Ethanol