title: Diffusely discordant In-111 WBC/Tc-99m SC bone marrow uptake. A possible chemotherapeutic effect.
abstract: In-111 WBC scintigraphy in a woman with relapsed acute lymphoid leukemia demonstrated normal uptake of white blood cells by the liver and spleen, but virtually absent bone marrow activity. Tc-99m SC imaging confirmed normal marrow function and distribution. A bone marrow biopsy revealed mildly hypocellular, regenerating marrow without leukemic infiltration. The effects of systemic cytotoxic chemotherapy on marrow reticuloendothelial function may have been responsible for this discordant uptake.
authors.affiliation: Department of Radiology, New England Medical Center, Boston, Massachusetts, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Achong
authors.forename: E
authors.initials: E
authors.lastname: Oates
mesh_terms: D001853:Bone Marrow / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007945:Leukemia, Lymphoid / Q000000981:diagnostic imaging*; D007962:Leukocytes; D008875:Middle Aged; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid
chemical_list: D007205:Indium Radioisotopes; D013671:Technetium Tc 99m Sulfur Colloid