Minimum bactericidal concentrations of Propionibacterium acnes isolates from cases of chronic endophthalmitis.
Six isolates of Propionibacterium acnes recovered from cases of chronic infectious endophthalmitis following extracapsular cataract extraction were tested for antibiotic susceptibility. All isolates were susceptible to penicillin, cefazolin, and vancomycin with a macrobroth dilution method. Minimum bactericidal concentrations testing at 72 h revealed that six of six isolates were killed by < or = 1.0 micrograms of vancomycin/ml, one of six isolates by < or = 1.0 micrograms of penicillin/ml, and zero of six isolates by < or = 1.0 micrograms cefazolin/ml.
Hall
G S
GS
Department of Microbiology, Cleveland Clinic, OH 44195-5140, USA.
Pratt-Rippin
K
K
Meisler
D M
DM
Washington
J A
JA
Roussel
T J
TJ
Miller
D
D
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002437:Cefazolin / Q000494:pharmacology; D002908:Chronic Disease; D009877:Endophthalmitis / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010406:Penicillins / Q000494:pharmacology; D011425:Propionibacterium acnes / Q000187:drug effects* / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010406:Penicillins; D014640:Vancomycin; D002437:Cefazolin