Effects of field size on the survival of pig epidermal colony-forming in situ after electron irradiation.
The survival of colony-forming cells in pig epidermis after irradiation was measured using different electron field sizes. The sensitivity of the colony-forming cells was characterized by D(o) = 2.5-3.0 Gy. There was an effect of field size, described approximately by: Dose (to give five colonies/cm2) (Gy) = (31 +/- 2) x Area-(0.048 +/- 0.015). The effect of field size was less than found previously using tolerance to skin reactions (area exponent = 0.16). This work indicates for the first time that the effects of different large field sizes in skin can be detected at the level of colony-forming cell survival.
Chen
F D
FD
School of Medical Technology, National Yang-Ming University, Taipei, Taiwan, ROC.
Chen
K Y
KY
Lee
Y L
YL
Yu
C
C
D000818:Animals; D002244:Carbon; D002470:Cell Survival / Q000528:radiation effects*; D003114:Colony-Forming Units Assay; D004396:Coloring Agents; D004307:Dose-Response Relationship, Radiation; D004583:Electrons; D006801:Humans; D008297:Male; D051379:Mice; D010315:Particle Accelerators; D012867:Skin / Q000166:cytology / Q000528:radiation effects*; D013045:Species Specificity; D013194:Staining and Labeling; D013552:Swine
D004396:Coloring Agents; C028433:chinese ink; D002244:Carbon