Tumour vasculature--a potential therapeutic target.
The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targeting of vascular proliferation antigens as cancer treatments.
Baillie
C T
CT
University Department of Surgery, Royal Free Hospital and School of Medicine, London, UK.
Winslet
M C
MC
Bradley
N J
NJ
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000098:blood supply* / Q000628:therapy*; D009389:Neovascularization, Pathologic / Q000188:drug therapy / Q000628:therapy*