Molecular epidemiology of HIV-1 in Madrid.
Thirteen HIV-1 isolates from patients of different risk groups in Madrid (Spain) have been analyzed at the genetic level. Two distinct lineages of subtype B have been detected among the HIV-1 circulating in this area: one was related to SF-2/RF strains, whereas the other consists of a more heterogeneous group related to reference strain III-B. Variants of each lineage appeared to circulate preferentially within a risk group: III-B among intravenous drug users, and RF/SF-2 among male homosexuals.
Rojas
J M
JM
Centro de Biología Celular y Retrovirus, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Dopazo
J
J
Nájera
I
I
Sánchez-Palomino
S
S
Olivares
I
I
Martin
M J
MJ
Bernal
A
A
García Saiz
A
A
Nájera
R
R
López-Galíndez
C
C
D000328:Adult; D001483:Base Sequence; D002648:Child; D002675:Child, Preschool; D005260:Female; D005814:Genes, Viral / Q000235:genetics; D015658:HIV Infections / Q000453:epidemiology / Q000382:microbiology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D013030:Spain / Q000453:epidemiology; D013045:Species Specificity