[Effect of Cladonia alpestris on Trichomonas vaginalis in vitro].
In this paper, an experimental research is reported on the effect of water extract of Cladonia alpestris and S-(-) usnic acid on Trichomonas vaginalis in vitro. The results showed that both the water extract of Cladonia alpestris and S-(-)usnic acid exhibited a strong effect against Trichomonas vaginalis in vitro. As the time of action of the agents was prolonged, the mortality of Trichomonas vaginalis increased. For S-(-) usnic acid, 0.4 mg/ml was the lowest effective concentration against Trichomonas vaginalis in vitro. No remarkable differences were found in the effect of the S-(-)usnic acid and metronidazole at concentrations of 0.4 mg/ml and 0.6 mg/ml.
Wu
J
J
Department of Parasitology, Xi'an Medical University.
Zhang
M
M
Ding
D
D
Tan
T
T
Yan
B
B
D000818:Animals; D000994:Antitrichomonal Agents / Q000494:pharmacology*; D001572:Benzofurans / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D066298:In Vitro Techniques; D014246:Trichomonas vaginalis / Q000187:drug effects*
D000994:Antitrichomonal Agents; D001572:Benzofurans; D004365:Drugs, Chinese Herbal; C073339:usnic acid