title: High resolution matrix-assisted laser desorption/ionization time-of-flight analysis of single-stranded DNA of 27 to 68 nucleotides in length.
abstract: Mass spectra of single-stranded DNA oligonucleotides were acquired using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). Resolution enhancement using space-velocity correlation focusing allows for facile observation of different oligomers, the direct observation of individual DNA-metal adducts, and investigation of counter ion structure.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington 47405, USA.
authors.forename: N P
authors.initials: NP
authors.lastname: Christian
authors.forename: S M
authors.initials: SM
authors.lastname: Colby
authors.forename: L
authors.initials: L
authors.lastname: Giver
authors.forename: C T
authors.initials: CT
authors.lastname: Houston
authors.forename: R J
authors.initials: RJ
authors.lastname: Arnold
authors.forename: A D
authors.initials: AD
authors.lastname: Ellington
authors.forename: J P
authors.initials: JP
authors.lastname: Reilly
mesh_terms: D001483:Base Sequence; D018736:DNA Adducts / Q000032:analysis; D004277:DNA, Single-Stranded / Q000032:analysis*; D008969:Molecular Sequence Data; D009841:Oligonucleotides / Q000032:analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D018736:DNA Adducts; D004277:DNA, Single-Stranded; D009841:Oligonucleotides