title: [Quantitative evaluation of the duodenogastric reflux after cholecystectomy and transduodenal sphincteroplasty: experimental study in dogs].
abstract: The role of cholecystectomy and transduodenal sphincteroplasty on duodenogastric reflux (DGR) is still controversial. PURPOSE--To assess the effect of cholecystectomy alone, transduodenal sphincteroplasty alone and cholecystectomy combined with transduodenal sphincteroplasty on bile reflux into the stomach. METHODS--40 dogs were divided into four groups: control group (C) (n = 12), cholecystectomy group (Co) (n = 10), transduodenal sphincteroplasty group (Es) (n = 10) and cholecystectomy plus transduodenal sphincteroplasty group (Co+Es) (n = 8). A quantitative index of DGR was obtained in each case by determining the percentage of the intravenously injected 99m Technetium-DISIDA that was recovered in the gastric juice. RESULTS--The DGR was significantly higher in Co+Es group (mean: 2.26 +/- 2.69%) than in the C group (mean: 0.23 +/- 0.26%), and the Co group (mean: 1.52 +/- 1.77%) and the Es group (mean: 1.23 +/- 1.23%) (p < 0.05). The DGR did not differ significantly between C, Co and Es groups (p > 0.05). CONCLUSION--The results shows that only cholecystectomy plus sphincteroplasty increases duodenogastric reflux.
authors.affiliation: Serviço de Gastroenterologia Cirúrgica, Hospital das Clínicas da Faculdades de Medicina de Ribeirão Preto da Universidade de S. Paulo.
authors.forename: E de O
authors.initials: Ede O
authors.lastname: Marinho
authors.forename: J I
authors.initials: JI
authors.lastname: de Andrade
authors.forename: R
authors.initials: R
authors.lastname: Ceneviva
mesh_terms: D000818:Animals; D002763:Cholecystectomy / Q000009:adverse effects*; D004285:Dogs; D004383:Duodenogastric Reflux / Q000000981:diagnostic imaging / Q000209:etiology*; D007098:Imino Acids; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D013105:Sphincterotomy, Transduodenal / Q000009:adverse effects*; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019785:Technetium Tc 99m Disofenin