Polymyositis and chronic graft-versus-host disease: efficacy of intravenous gammaglobulin and methotrexate.
Polymyositis developed in a patient who had received a bone marrow transplant for the treatment of acute lymphoblastic leukemia 20 months earlier. It was a manifestation of chronic graft-versus-host disease associated with sclerodermatous changes of the skin and sicca syndrome. Polymyositis was treated successfully by polyvalent human intravenous immunoglobulin and methotrexate.
Blanche
P
P
Service de Médecine Interne, Hôpital Cochin, Université René Descartes, Paris, France.
Dreyfus
F
F
Sicard
D
D
D002908:Chronic Disease; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D017285:Polymyositis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology
D003879:Dermatologic Agents; D016756:Immunoglobulins, Intravenous; D008727:Methotrexate