title: Silicone gel sheeting in scar therapy.
abstract: The purpose of this study was to analyze the efficacy of silicone gel sheeting in the treatment of fresh and long-standing hypertrophic and keloid scars. All subjects applied the gel sheeting in the same fashion and wore it for twelve to twenty-four hours per day for at least two months. After at least six months' follow-up, twenty of thirty-six (56 percent) chronic scars were improved. Eleven of fourteen fresh hypertrophic scars (79 percent) did not recur after surgery during a similar follow-up period. Side effects were minimal. Silicone gel sheeting is safe and effective treatment for hypertrophic and keloid scars. The mechanism of action is not completely understood.
authors.forename: B E
authors.initials: BE
authors.lastname: Katz
mesh_terms: D001458:Bandages / Q000009:adverse effects; D002908:Chronic Disease; D017439:Cicatrix, Hypertrophic / Q000473:pathology / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*; D003869:Dermabrasion; D017453:Dermatitis, Irritant / Q000209:etiology; D005500:Follow-Up Studies; D005782:Gels; D006801:Humans; D007627:Keloid / Q000473:pathology / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*; D011182:Postoperative Care; D012008:Recurrence; D012828:Silicones / Q000009:adverse effects
chemical_list: D005782:Gels; D012828:Silicones