Evidence for a possible neuroanatomical basis for lexical processing of nouns and verbs.
Neuropsychological studies have revealed that brain-damaged patients may show impairments of specific word categories. This study reports the performance of three patients with impairments of the categories noun and verb. The first and second patients, with left frontal lobe atrophy, were impaired in naming and comprehension of verbs. The third patient, with striking atrophy of the left temporal lobe, was disproportionately impaired in naming and comprehension of nouns. These findings suggest that anatomically distinct neural systems in the temporal and frontal lobes of the dominant hemisphere might play a critical role in lexical processing of nouns and verbs, respectively.
Daniele
A
A
Institute of Neurology, Catholic University, Rome, Italy.
Giustolisi
L
L
Silveri
M C
MC
Colosimo
C
C
Gainotti
G
G
D000368:Aged; D000849:Anomia / Q000503:physiopathology* / Q000523:psychology; D001037:Aphasia / Q000503:physiopathology* / Q000523:psychology; D001284:Atrophy; D001925:Brain Damage, Chronic / Q000503:physiopathology* / Q000523:psychology; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D003952:Diagnostic Imaging; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology; D012660:Semantics; D013067:Speech Perception / Q000502:physiology*; D013068:Speech Production Measurement; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology