[An investigation on the present situation of HCV infection patients with liver diseases and in blood recipients in Baise District of Guang Xi].
ELISA was used to detect anti-HCV antibody in 179 serum samples of patients with various types of liver diseases and 41 serum samples of blood recipients in Baise district of Guang Xi. The results showed that 17.9% of patients with various types of liver diseases and 31.7% of blood recipients were anti-HCV positive. Among patients with liver diseases, the anti-HCV positive rate was 4.3% (1/23) in acute hepatitis (AH), 12.8% (10/78) in chronic hepatitis (CH), 28.6% (12/42) in liver cirrhosis (LC) and 25.0% (9/36) in hepatocellular carcinoma (HCC). As liver diseases became chronic, the anti-HCV positive rate tended to rise. The anti-HCV positive rate in LC was significantly higher than that in AH or CH (P < 0.05). The anti-HCV positive rate in HCC was not significantly different from that in AH or CH (P > 0.05 or 0.1). It was found that the anti-HCV positive rate in HBsAg-negative patients was significantly higher than that in HBsAg-positive patients (P < 0.05). The anti-HCV positive rate in liver diseases was not related to ALT (P > 0.05). In blood recipients, the anti-HCV positive rate was closely related to the number of transfusion and the activity of ALT.
Du
G
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Baise City People's Hospital, Guang Xi.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000453:epidemiology*; D018937:Hepatitis C Antibodies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D065227:Transfusion Reaction
D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies