[Data on the pharmacology of a new enzyme complex for replacement therapy in children].
A model of experimental pancreatitis was used to study the enzymatic compensatory properties of a new polyenzymatic complex. When given in a dose of 70 mg/kg, the complex was found to normalize amylolytic, lipolytic and partially proteolytic activities in the small intestinal cavity of rats. The complex had some advantages in exhibiting its pharmacological effect over some foreign drugs.
Maslova
N F
NF
Bomko
T V
TV
D000208:Acute Disease; D000681:Amylases / Q000627:therapeutic use; D000818:Animals; D004063:Digestion / Q000187:drug effects; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D006026:Glycoside Hydrolases / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D010195:Pancreatitis / Q000188:drug therapy / Q000201:enzymology; D010447:Peptide Hydrolases / Q000494:pharmacology* / Q000627:therapeutic use; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats
D004338:Drug Combinations; D010936:Plant Extracts; C021910:Oraza; C061937:nigedase; C078601:somilase; D000681:Amylases; D006026:Glycoside Hydrolases; D010447:Peptide Hydrolases