title: Exocytotic Ca2+ channels in mammalian central neurons.
abstract: Intracellular Ca2+ initiates physiological events as diverse as gene transcription, muscle contraction, cell division and exocytosis. Predictably, the metabolic machinery that elicits and responds to changes in intracellular Ca2+ is correspondingly heterogeneous. This review focuses on one element of this complex web that is of particular importance to neurobiologists: identifying which members of the voltage-dependent Ca(2+)-channel superfamily are responsible for the Ca2+ that enters nerve terminals and elicits vesicular release of chemical transmitters.
authors.affiliation: Dept of Physiology, Tufts University School of Medicine, Boston, MA 02111, USA.
authors.forename: K
authors.initials: K
authors.lastname: Dunlap
authors.forename: J I
authors.initials: JI
authors.lastname: Luebke
authors.forename: T J
authors.initials: TJ
authors.lastname: Turner
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015220:Calcium Channels / Q000235:genetics / Q000378:metabolism*; D020864:Calcium Channels, N-Type; D002490:Central Nervous System / Q000166:cytology* / Q000378:metabolism*; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D009474:Neurons / Q000378:metabolism* / Q000502:physiology
chemical_list: D015220:Calcium Channels; D020864:Calcium Channels, N-Type