Visual hallucinations following treatment with vincristine.
Peripheral neuropathy is a common side effect of vincristine therapy. However, side effects due to central nervous system (CNS) toxicity following intravenous administration are rare. We report two patients who developed visual hallucinations during treatment with vincristine.
Ghosh
K
K
Department of Haematology, Leicester Royal Infirmary, UK.
Sivakumaran
M
M
Murphy
P
P
Chapman
C S
CS
Wood
J K
JK
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D002330:Carmustine / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006212:Hallucinations / Q000139:chemically induced*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000150:complications / Q000188:drug therapy; D008297:Male; D008558:Melphalan / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000188:drug therapy; D011239:Prednisolone / Q000008:administration & dosage; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D016879:Salvage Therapy; D012701:Serotonin / Q000737:chemistry; D013329:Structure-Activity Relationship; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry
D001761:Bleomycin; D012701:Serotonin; D011344:Procarbazine; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; D008558:Melphalan; D002330:Carmustine; D011241:Prednisone; D008727:Methotrexate