title: Basal and exercise-induced changes in plasma catecholamines: relationship to age, smoking habits and sampling times.
abstract: Contrary to earlier investigations, we have previously shown that the initial increase in venous plasma noradrenaline (NA) during exercise did not differ in young and elderly non-smoking subjects exercising at the same relative workload (75%), and that the greatest increase at maximal workload was observed in the young subjects. In order to determine whether the observed discrepancy could be explained by long-term smoking, plasma NA and adrenaline (A) were evaluated in eight elderly male smokers (mean age 67 years). The results were compared with data reported previously [Jensen et al. (1994) Exercise-induced changes in plasma catecholames and neuropeptide Y: relation to age and sampling times. J Appl Physiol, 76, 1269-1273] in seven young (mean age 27 years) and seven elderly (mean age 61 years) non-smoking male subjects. As shown earlier, basal plasma NA was significantly increased in elderly smokers compared to young and elderly non-smokers. During exercise at 75% of maximal work capacity, no difference was observed between elderly smokers and non-smokers. No difference in plasma A was found between elderly smokers and non-smokers either at rest or during exercise. These findings indicate that the exercise-induced increase in plasma NA did not differ in elderly smokers and non-smokers despite increased resting levels in the former group, and that the increase in the elderly subjects was not augmented compared to that in young subjects.
authors.affiliation: Department of Internal Medicine and Endocrinology, Herlev University Hospital, Denmark.
authors.forename: E W
authors.initials: EW
authors.lastname: Jensen
authors.forename: K
authors.initials: K
authors.lastname: Espersen
authors.forename: I L
authors.initials: IL
authors.lastname: Kanstrup
authors.forename: N J
authors.initials: NJ
authors.lastname: Christensen
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood*; D002395:Catecholamines / Q000097:blood*; D004837:Epinephrine / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D010101:Oxygen Consumption; D012907:Smoking / Q000097:blood*; D013997:Time Factors
chemical_list: D002395:Catecholamines; D009638:Norepinephrine; D004837:Epinephrine