Intermediate filaments: new proteins, some answers, more questions.
The past year has seen significant progress in the characterization of intermediate filament proteins. New proteins have been identified and physiologically significant differences between known proteins have been revealed. Changes in intermediate filament organization have been linked to changes in cell behavior, and mutational analyses are beginning to reveal the connection between intermediate filament expression, network formation, cellular behavior and disease.
Klymkowsky
M W
MW
University of Colorado, Boulder, USA.
D000818:Animals; D014408:Biomarkers, Tumor / Q000737:chemistry; D003893:Desmin / Q000502:physiology; D007381:Intermediate Filament Proteins / Q000502:physiology*; D007633:Keratins / Q000502:physiology; D016900:Neurofilament Proteins / Q000502:physiology; D014746:Vimentin / Q000502:physiology
D014408:Biomarkers, Tumor; D003893:Desmin; D007381:Intermediate Filament Proteins; D016900:Neurofilament Proteins; D014746:Vimentin; D007633:Keratins