Osteoradionecrosis of the hyoid induced by combined modality therapy for laryngeal carcinoma.
Contemporary management of laryngeal carcinoma often incorporates multiple modalities of therapy. We report a case of osteoradionecrosis of the hyoid bone in a patient treated with surgery, chemotherapy, and radiation therapy for a supraglottic squamous cell carcinoma. A discussion regarding pathophysiology, radiation dosimetry and treatment options is also presented.
Robertson
J S
JS
McCollough Plastic Surgery Clinic, Birmingham, Alabama 35205, USA.
Frauenhoffer
E E
EE
Stryker
J
J
Schaitkin
B
B
Velkley
D E
DE
McGinn
J D
JD
D002277:Carcinoma / Q000473:pathology* / Q000532:radiotherapy* / Q000628:therapy; D003131:Combined Modality Therapy / Q000009:adverse effects; D004358:Drug Therapy; D006801:Humans; D006928:Hyoid Bone / Q000473:pathology* / Q000528:radiation effects*; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy* / Q000628:therapy; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000209:etiology* / Q000473:pathology; D011829:Radiation Dosage