title: Virulence in Actinobacillus pleuropneumoniae and RTX toxins.
abstract: RTX toxins are pore-forming, cytolytic protein toxins that occur widely among pathogenic Gram-negative bacteria. RTX toxins appear to play a direct role in the virulence of Actinobacillus pleuropneumoniae, the etiological agent of porcine pleuropneumonia. This discovery has led to the development of new diagnostic and epidemiological tools, as well as vaccines, that are useful for a broad variety of serotypes.
authors.affiliation: Institute for Veterinary Bacteriology, University of Berne, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Frey
mesh_terms: D016977:Actinobacillus pleuropneumoniae / Q000472:pathogenicity*; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D005838:Genotype; D006460:Hemolysin Proteins; D010641:Phenotype; D014774:Virulence
chemical_list: C085361:ApxII toxin, bacteria; C079721:ApxIII toxin protein, Actinobacillus; D001426:Bacterial Proteins; D006460:Hemolysin Proteins; C087744:ApxI toxin, Bacteria