title: The Abrams-Griffiths nomogram.
abstract: The treatment of benign prostatic hyperplasia and the definition of bladder-outlet obstruction has preoccupied urologists and researchers in recent years. Bladder-outlet obstruction can be defined only by pressure-flow measurement. Various methods of analysis of pressure-flow data have been proposed. The Abrams-Griffiths nomogram is an easy method of classifying these data to distinguish between the presence or absence of obstruction. Using the values for the maximal flow and the corresponding voiding detrusor pressure a point can be plotted on the nomogram that determines whether the bladder outlet is obstructed, unobstructed, or equivocally obstructed. For those that fall in the equivocal zone, further criteria for the mean slope of the pressure-flow plot and the minimal voiding detrusor pressure are used to determine whether there is obstruction or not. The nomogram's prognostic value in predicting the outcome of prostatectomy has been studied and found to be excellent. The Abrams-Griffiths nomogram can be modified by assigning an Abrams-Griffiths number to each set of pressure-flow data. This number is easy to calculate and use and gives a continuous variable that can be used to evaluate the effects of therapy. Although the Abrams-Griffiths nomogram and number are somewhat simplistic, none of the more complex methods of pressure-flow analysis have been shown to be better predictors of treatment outcome to date.
authors.affiliation: Bristol Urological Institute, Southmead Hospital, UK.
authors.forename: C S
authors.initials: CS
authors.lastname: Lim
authors.forename: P
authors.initials: P
authors.lastname: Abrams
mesh_terms: D003627:Data Interpretation, Statistical; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D014525:Urethral Stricture / Q000150:complications / Q000503:physiopathology; D014563:Urodynamics / Q000502:physiology*