title: Polymyositis and chronic graft-versus-host disease: efficacy of intravenous gammaglobulin and methotrexate.
abstract: Polymyositis developed in a patient who had received a bone marrow transplant for the treatment of acute lymphoblastic leukemia 20 months earlier. It was a manifestation of chronic graft-versus-host disease associated with sclerodermatous changes of the skin and sicca syndrome. Polymyositis was treated successfully by polyvalent human intravenous immunoglobulin and methotrexate.
authors.affiliation: Service de Médecine Interne, Hôpital Cochin, Université René Descartes, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Blanche
authors.forename: F
authors.initials: F
authors.lastname: Dreyfus
authors.forename: D
authors.initials: D
authors.lastname: Sicard
mesh_terms: D002908:Chronic Disease; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D017285:Polymyositis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology
chemical_list: D003879:Dermatologic Agents; D016756:Immunoglobulins, Intravenous; D008727:Methotrexate