[Kinin antagonists in the treatment of acute stenosing laryngotracheitis in children].
The treatment of 97 infants aged from 3 months to 2 years included: nasotracheal intubation (56 patients); i. v. injection, drops (77 patients) or aerosol inhalations (20 cases) of trasylol, kontrikal or gordox; inhalations of epsilon aminocaproic acid (12 cases); glucocorticoids (locally, inhalations, laryngeal drop infusions); local and oral bioantioxidants; noradrenaline for local vasoconstriction. The addition of antikinin medication to the complex of pathogenetically differentiated means which are also proteolytic enzyme inhibitors reduced the frequency and duration of tracheal intubation, duration of laryngeal stenosis by half. Systemic and local administration of antikinin drugs is advocated starting on the first post-diagnosis days, except cases of advanced acute inflammation in the presence of infiltrates in the cavum infraglotticum when antikinin, antihistamine and vasoconstrictors proved ineffective.
Aslanian
G G
GG
D000208:Acute Disease; D000284:Administration, Oral; D000336:Aerosols; D015119:Aminocaproic Acid / Q000008:administration & dosage; D000975:Antioxidants / Q000008:administration & dosage; D007611:Aprotinin / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007705:Kinins / Q000037:antagonists & inhibitors*; D007827:Laryngitis / Q000150:complications / Q000188:drug therapy*; D007829:Laryngostenosis / Q000209:etiology; D009638:Norepinephrine / Q000008:administration & dosage; D012138:Respiratory Therapy; D014135:Tracheal Stenosis / Q000209:etiology; D014136:Tracheitis / Q000150:complications / Q000188:drug therapy*; D014361:Trypsin Inhibitors / Q000008:administration & dosage
D000336:Aerosols; D000975:Antioxidants; D005938:Glucocorticoids; D007705:Kinins; D014361:Trypsin Inhibitors; C011475:gordox; D007611:Aprotinin; D015119:Aminocaproic Acid; D009638:Norepinephrine