title: Patent ductus venosus associated with a hyperintense globus pallidum on T1-weighted magnetic resonance imaging and pulmonary hypertension.
abstract: We report the case of a 13-year-old Japanese boy with a patent ductus venosus. He experienced mild disorientation and hallucination at age 8 years. Hyperammonaemia was discovered at age 12 years. Brain MRI demonstrated multiple intracranial hyperintense lesions, mainly in the globus pallidum, which suggested portosystemic encephalopathy. Patent ductus venosus was demonstrated by abdominal ultrasonography and angiography. Cardiopulmonary investigation revealed pulmonary hypertension. An intracranial hyperintense lesion observed on T1-weighted MRI may be an initial clue for discovering a patent ductus venosus in asymptomatic patients.
  
  
  CONCLUSIONS
  When patent ductus venosus is disclosed, pulmonary hypertension should be sought, as in cases with other portosystemic shunts.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yanai
authors.forename: T
authors.initials: T
authors.lastname: Minami
authors.forename: K
authors.initials: K
authors.lastname: Sonoda
authors.forename: K
authors.initials: K
authors.lastname: Gondo
authors.forename: K
authors.initials: K
authors.lastname: Tasaki
authors.forename: T
authors.initials: T
authors.lastname: Hijii
authors.forename: J
authors.initials: J
authors.lastname: Fukushige
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: T
authors.initials: T
authors.lastname: Hirata
authors.forename: T
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000293:Adolescent; D000641:Ammonia / Q000097:blood; D005917:Globus Pallidus / Q000473:pathology*; D006501:Hepatic Encephalopathy / Q000175:diagnosis*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis*; D008111:Liver Function Tests; D008279:Magnetic Resonance Imaging; D008297:Male; D011169:Portal Vein / Q000002:abnormalities*; D014682:Vena Cava, Inferior / Q000002:abnormalities
chemical_list: D000641:Ammonia