title: Detection of a C-insertion polymorphism within the human tumor necrosis factor alpha (TNFA) gene.
abstract: We have identified a C-insertion polymorphism in the 5'UTR of the first exon of the human tumor necrosis factor alpha (TNFA) gene. TNFA is a cytokine that plays an important role in the inflammatory response.
authors.affiliation: Department of Rheumatology, University Hospital Leiden, The Netherlands.
authors.forename: B M
authors.initials: BM
authors.lastname: Brinkman
authors.forename: E L
authors.initials: EL
authors.lastname: Kaijzel
authors.forename: T W
authors.initials: TW
authors.lastname: Huizinga
authors.forename: M J
authors.initials: MJ
authors.lastname: Giphart
authors.forename: F C
authors.initials: FC
authors.lastname: Breedveld
authors.forename: C L
authors.initials: CL
authors.lastname: Verweij
mesh_terms: D001483:Base Sequence; D002896:Chromosomes, Human, Pair 6; D004251:DNA Transposable Elements / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D014409:Tumor Necrosis Factor-alpha