title: Basic research.
abstract: Basic research is currently investigating the molecular cascade associated with bladder cancer development. Many new findings are potential leads towards the improvement of the diagnosis and prognosis of this disease. Special care, however, should be taken in the design of protocols for clinical evaluation of the value of these markers. Some initial guidelines have been put forward in this report.
authors.affiliation: St.-Radboud Ziekenhuis, Nijimegen, The Netherlands.
authors.forename: F
authors.initials: F
authors.lastname: Debruyne
authors.forename: O
authors.initials: O
authors.lastname: Yoshida
authors.forename: C
authors.initials: C
authors.lastname: Olsson
authors.forename: J
authors.initials: J
authors.lastname: Bauer
authors.forename: W
authors.initials: W
authors.lastname: Höltl
authors.forename: Y
authors.initials: Y
authors.lastname: Kakehi
authors.forename: J A
authors.initials: JA
authors.lastname: Schalken
authors.forename: A
authors.initials: A
authors.lastname: Borkowsky
mesh_terms: D000483:Alleles; D016158:Genes, p53; D006801:Humans; D009154:Mutation; D012106:Research; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy