Some suspected periodontopathogens and serum antibody response in adult long-duration insulin-dependent diabetics.
The subgingival microflora and serum antibody response were examined in long-duration insulin-dependent diabetics and age- and sex-matched non-diabetics. The material consisted of 9 diabetics aged 40-49 years and 19 aged 50-59 years, 13 non-diabetics aged 40-49 years and 21 aged 50-59 years. The bacterial species studied (Actinobacillus actinomycetemcomitans, Campylobacter rectus, Capnocytophaga spp, Eikenella corrodens, Fusobacterium nucleatum, Porphyromonas gingivalis, Prevotella intermedia) were recovered in diabetics as well as in non-diabetics. Significantly more diabetics in both age groups harboured P. gingivalis compared to non-diabetics. Prevalence of P. gingivalis was associated with deepened periodontal pockets among non-diabetics but not among diabetics. In diabetics and non-diabetics, the serum antibody titres for most antigens were similar.
Thorstensson
H
H
Department of Periodontology, Institute for Postgraduate Dental Education, Jönköping, Sweden.
Dahlén
G
G
Hugoson
A
A
D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000276:immunology / Q000302:isolation & purification; D000907:Antibodies, Bacterial / Q000097:blood*; D001419:Bacteria / Q000302:isolation & purification*; D002167:Campylobacter / Q000276:immunology / Q000302:isolation & purification; D002206:Capnocytophaga / Q000276:immunology / Q000302:isolation & purification; D016022:Case-Control Studies; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000382:microbiology*; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology / Q000382:microbiology*; D016124:Eikenella corrodens / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D016967:Fusobacterium nucleatum / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010514:Periodontal Pocket / Q000382:microbiology; D016966:Porphyromonas gingivalis / Q000276:immunology / Q000302:isolation & purification; D018713:Prevotella intermedia / Q000276:immunology / Q000302:isolation & purification
D000907:Antibodies, Bacterial