title: Plasma granulocyte colony stimulating factor concentrations in pregnant women.
abstract: We measured the plasma granulocyte colony stimulating factor (G-CSF) concentrations in pregnant women to evaluate the association between G-CSF and increased neutrophil counts that has been observed during pregnancy. We examined 96 pregnant and 10 nonpregnant women. The G-CSF concentrations were assayed using a sandwich enzyme immunoassay. The G-CSF concentrations in pregnant women were significantly higher at all times than those of nonpregnant women. The G-CSF concentrations were also significantly higher during than before labor. The plasma G-CSF concentrations were positively correlated with the neutrophil counts during the 3rd trimester only. In conclusion, increased G-CSF concentrations may be related to the increases in neutrophil counts in pregnant women, especially during the 3rd trimester.
authors.affiliation: Department of Obstetrics and Gynecology, Osaka City University Medical School, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Umesaki
authors.forename: H
authors.initials: H
authors.lastname: Fukumasu
authors.forename: M
authors.initials: M
authors.lastname: Miyama
authors.forename: M
authors.initials: M
authors.lastname: Kawabata
authors.forename: S
authors.initials: S
authors.lastname: Ogita
mesh_terms: D000328:Adult; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000097:blood*; D006801:Humans; D007124:Immunoenzyme Techniques; D007958:Leukocyte Count; D009504:Neutrophils; D011247:Pregnancy / Q000097:blood*; D011263:Pregnancy Trimester, Third
chemical_list: D016179:Granulocyte Colony-Stimulating Factor