Amniotic alpha-fetoprotein in the prenatal diagnosis of congenital nephrotic syndrome of the Finnish type.
Congenital nephrosis of the Finnish type (CNF) is rare outside Finland, where the incidence may be as high as 1 in 2000 live births. Neonates with the disorder develop renal failure within the first months of life and without renal transplantation, the prognosis is extremely poor. This case report describes a woman's three pregnancies, two of which were affected with CNF.
Morris
J
J
University of Sydney, Department of Obstetrics and Gynaecology, Nepean Hospital, Penrith, Australia.
Ellwood
D
D
Kennedy
D
D
Knight
J
J
D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry*; D005260:Female; D005387:Finland; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D009404:Nephrotic Syndrome / Q000151:congenital* / Q000175:diagnosis* / Q000473:pathology; D011247:Pregnancy; D011296:Prenatal Diagnosis; D016216:Ultrasonography, Prenatal; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins