Swarming and pathogenicity of Proteus mirabilis in the urinary tract.
Proteus mirabilis is best known for its pattern of swarming differentiation on agar plates, as well as for its association with the development of renal stones in patients with urinary tract infection. Urease and flagella appear to contribute most significantly to virulence, with fimbriae playing a more subtle role, whereas hemolysin does not appear to contribute significantly to pathogenesis.
Mobley
H L
HL
Dept of Medicine, University of Maryland School of Medicine, Baltimore 21201, USA.
Belas
R
R
D000818:Animals; D006801:Humans; D011512:Proteus Infections / Q000382:microbiology*; D011513:Proteus mirabilis / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D014552:Urinary Tract Infections / Q000382:microbiology*