title: Exogenous testosterone alters expression pattern of cell recognition molecules in brains of juvenile zebra finches.
abstract: We assessed spatio-temporal expression of tenascin and janusin by immunocytochemistry in testosterone-treated zebra finches and in untreated controls. These cell recognition molecules and components of the extracellular matrix mediate neurone-glia interactions, which are crucial for differentiation of ordered neural structures. We describe boundaries for the spatio-temporal expression of cell recognition molecules that highly correlate with the song motor centres as defined by combined neuroanatomical and ethological studies on song vocalization. The expression of janusin is accelerated by exogenous testosterone.
authors.affiliation: Department of Neurobiology, Swiss Federal Institute of Technology, Zürich.
authors.forename: P
authors.initials: P
authors.lastname: Burkhardt-Holm
authors.forename: K W
authors.initials: KW
authors.lastname: Kafitz
authors.forename: H R
authors.initials: HR
authors.lastname: Güttinger
authors.forename: M
authors.initials: M
authors.lastname: Schachner
mesh_terms: D000367:Age Factors; D000818:Animals; D001717:Birds / Q000502:physiology*; D001921:Brain / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D015816:Cell Adhesion Molecules, Neuronal / Q000235:genetics / Q000378:metabolism*; D002454:Cell Differentiation / Q000502:physiology; D048429:Cell Size; D016326:Extracellular Matrix Proteins / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression / Q000187:drug effects; D007150:Immunohistochemistry; D009474:Neurons / Q000502:physiology; D019063:Tenascin; D013739:Testosterone / Q000494:pharmacology*; D014828:Vocalization, Animal / Q000502:physiology
chemical_list: D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D019063:Tenascin; C074638:tenascin R; D013739:Testosterone