title: Intraorbital injection of amphotericin B for palliative treatment of Aspergillus orbital abscess.
abstract: We report successful palliative treatment of an Aspergillus fumigatus orbital mass in a patient with acquired immunodeficiency syndrome by direct injection of amphotericin B into the abscess cavity. This case presents intraorbital injection of amphotericin B as an alternative to surgical debridement of Aspergillus orbital infection. In patients who are unable or unwilling to undergo more aggressive treatment, this procedure appears to limit morbidity while still providing effective palliative therapy.
authors.affiliation: Department of Ophthalmology, Ohio State University, Columbus.
authors.forename: K V
authors.initials: KV
authors.lastname: Cahill
authors.forename: C D
authors.initials: CD
authors.lastname: Hogan
authors.forename: S L
authors.initials: SL
authors.lastname: Koletar
authors.forename: M
authors.initials: M
authors.lastname: Gersman
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000038:Abscess / Q000188:drug therapy*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy*; D015821:Eye Infections, Fungal / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008297:Male; D009916:Orbital Diseases / Q000188:drug therapy* / Q000382:microbiology; D010166:Palliative Care
chemical_list: D000666:Amphotericin B