title: Growth-phase regulation of plasmid virulence genes in Salmonella.
abstract: Virulence genes in the genus Salmonella are regulated by growth phase and by environmental signals, which allows a sequential program of expression during infection. Conditions that promote the expression of loci required in systemic infection, including the plasmid-encoded spv genes, are the opposite of the factors that induce genes involved in the invasion of epithelial cells in the gastrointestinal tract.
authors.affiliation: Dept of Medicine 0640, UCSD School of Medicine, La Jolla, CA 92093-0640, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Guiney
authors.forename: S
authors.initials: S
authors.lastname: Libby
authors.forename: F C
authors.initials: FC
authors.lastname: Fang
authors.forename: M
authors.initials: M
authors.lastname: Krause
authors.forename: J
authors.initials: J
authors.lastname: Fierer
mesh_terms: D000818:Animals; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D010957:Plasmids; D012475:Salmonella / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity*; D014774:Virulence / Q000235:genetics