Paroxetine in the treatment of inpatients with non-delusional endogenous or neurotic depression.
The clinical course of 35 depressed inpatients (19 women, 16 men; 19 endogenous, 16 neurotic depression (ICD-9 diagnoses); mean age 46.7 years) who were treated with paroxetine 20 mg/d was observed over 21 days using the Hamilton Depression Scale (HAMD). For both types of depression there was a significant decrease from day 1 to day 21 in the mean HAMD total score and in a subscore of cognitive and somatic items. The mean value of the HAMD suicide item increased in 3 cases and decreased in 25.
Wolfersdorf
M
M
Department of Psychiatry I, University of Ulm, Psychiatric State Hospital Weissenau, Ravensburg-Weissenau, FRG.
Barg
T
T
König
F
F
Leibfarth
M
M
Grünewald
I
I
Wetzel
S
S
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000009:adverse effects / Q000627:therapeutic use*; D010343:Patient Admission; D010555:Personality Inventory; D012307:Risk Factors; D013405:Suicide / Q000523:psychology; D000092864:Suicide Prevention
D017374:Paroxetine