Mesothelial cyst of the adrenal gland.
A case of mesothelium-lined cyst of the adrenal gland is reported. Although more than 300 adrenal cysts have been reported in the literature, epithelial cell-lined cysts are rare and comprise only 9% of the cases. An adrenal cyst was found, the lining cells of which had features consistent with mesothelial cells. The inner surface of the cyst was lined by a single layer of cuboidal cells, which showed alcian blue positive cellular outline. Immunohistochemically, the lining cells were positively stained for keratin, epithelial membrane antigen and CA-125. Electron microscopic examination revealed many long complex microvilli and desmosomes in the lining cells. There was a basal lamina beneath the cell layer. These morphological and immunohistochemical findings indicated that the lining cell is derived from mesothelium.
Fukushima
N
N
Department of Diagnostic Pathology, Kanto Teishin Hospital, Tokyo, Japan.
Oonishi
T
T
Yamaguchi
K
K
Fukayama
M
M
D000307:Adrenal Gland Diseases / Q000378:metabolism / Q000473:pathology*; D000311:Adrenal Glands / Q000737:chemistry / Q000473:pathology*; D018394:CA-125 Antigen / Q000032:analysis; D003560:Cysts / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007564:Japan; D007633:Keratins / Q000032:analysis; D008562:Membrane Glycoproteins / Q000032:analysis; D008875:Middle Aged; D018396:Mucin-1; D009077:Mucins / Q000032:analysis
D018394:CA-125 Antigen; D008562:Membrane Glycoproteins; D018396:Mucin-1; D009077:Mucins; D007633:Keratins