[Superinfection of hepatitis viruses].
Using ELISA method, anti-HAV-IgM and anti-HCV were determined in 493 blood donors and 192 patients with HBV infection. The positive rate of anti-HCV in blood donors was 1.62%. The superinfection rates of HBV and HAV, HBV and HCV, HBV, HAV and HCV in patients with HBV infection were 16.7%, 3.13% and 0.52%, respectively. The incidence of hepatitis B viral replication marker was found to be lower in patients with superinfection of types A and B and/or C hepatitis viruses than in those with HBV infection alone. The prolonged course was found to be longer and the degree severer in patients with superinfection of types A and B and/or C hepatitis viruses than in those with HAV or HBV or HCV infection alone. The results suggest that those patients with superinfection of types A and B and/or C hepatitis viruses showed poor prognosis and prolonged course, and many patients with chronic Type A hepatitis resulted from superinfection HBV and/or HCV.
Chen
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Air Force Fuzhou Hospital, Fuzhou.
Liu
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Li
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D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006506:Hepatitis A / Q000276:immunology*; D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006526:Hepatitis C / Q000276:immunology*; D018937:Hepatitis C Antibodies; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015163:Superinfection / Q000276:immunology
D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies