title: An in vitro transcription assay for probing drug-DNA interactions during active transcription of DNA.
authors.affiliation: Department of Biochemistry, La Trobe University, Bundoora, Victoria, Australia.
authors.forename: D R
authors.initials: DR
authors.lastname: Phillips
authors.forename: D M
authors.initials: DM
authors.lastname: Crothers
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D007202:Indicators and Reagents; D007700:Kinetics; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D010957:Plasmids; D011401:Promoter Regions, Genetic; D012313:RNA / Q000096:biosynthesis*; D011865:Radioisotope Dilution Technique; D012265:Ribonucleotides / Q000378:metabolism; D013698:Templates, Genetic; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D004364:Pharmaceutical Preparations; D010761:Phosphorus Radioisotopes; D012265:Ribonucleotides; D012313:RNA; D004247:DNA