Evidence for direct modification of NF kappa B by the tyrosine kinase inhibitor, herbimycin A.
Mahon
T M
TM
Department of Biochemistry, Trinity College Dublin, Ireland.
O'Neill
L A
LA
D000818:Animals; D016227:Benzoquinones; D002460:Cell Line; D004229:Dithiothreitol / Q000494:pharmacology; D007375:Interleukin-1 / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D047029:Lactams, Macrocyclic; D008623:Mercaptoethanol / Q000494:pharmacology; D051379:Mice; D016328:NF-kappa B / Q000187:drug effects / Q000378:metabolism*; D019000:Phosphotyrosine; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D011809:Quinones / Q000494:pharmacology*; D017828:Rifabutin / Q000031:analogs & derivatives; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D014443:Tyrosine / Q000031:analogs & derivatives / Q000032:analysis
D016227:Benzoquinones; D007375:Interleukin-1; D047029:Lactams, Macrocyclic; D016328:NF-kappa B; D011809:Quinones; D017828:Rifabutin; D019000:Phosphotyrosine; D014443:Tyrosine; D008623:Mercaptoethanol; C020754:herbimycin; D011505:Protein-Tyrosine Kinases; D013755:Tetradecanoylphorbol Acetate; D004229:Dithiothreitol