SCID mice reconstituted with Oct-2-deficient lymphocytes can cure Leishmania major infection and generate normal antigen-specific T cells.
Scheerlinck
J P
JP
Walter and Eliza Hall Institute for Medical Research, Royal Melbourne Hospital, Victoria, Australia.
Corcoran
L M
LM
Handman
E
E
D000818:Animals; D004268:DNA-Binding Proteins / Q000276:immunology*; D000939:Epitopes; D007371:Interferon-gamma / Q000096:biosynthesis; D016773:Leishmaniasis, Cutaneous / Q000276:immunology / Q000628:therapy*; D008213:Lymphocyte Activation; D051379:Mice; D016513:Mice, SCID; D050813:Octamer Transcription Factor-2; D015800:Protozoan Proteins / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology / Q000637:transplantation*; D014157:Transcription Factors
D004268:DNA-Binding Proteins; D000939:Epitopes; D050813:Octamer Transcription Factor-2; C489206:Pou2f2 protein, mouse; D015800:Protozoan Proteins; D014157:Transcription Factors; D007371:Interferon-gamma