title: Hemodynamic alterations during massive incisional hernioplasty.
abstract: BACKGROUND
  The operative treatment of a large abdominal incisional hernia increases intra-abdominal pressure (IAP). This study was done to verify if this IAP elevation acts on the cardiocirculatory function.
  
  
  METHODS
  Hemodynamic measurements were performed in five patients who underwent massive incisional hernioplasty before and after abdominal wall closure.
  
  
  RESULTS
  Reduction of a large abdominal hernia increases (+226 percent) IAP, which can produce serious hemodynamic alterations, manifested in two patients by a fall of cardiac output (-30 percent), without significant variations of heart rate and arterial pressure. Cardiac output is decreased secondary to decreased venous return, despite the increase in measured central venous pressure (CVP) and pulmonary capillary wedge pressure (PCWP).
  
  
  CONCLUSIONS
  During massive incisional hernioplasty, CVP cannot be used as an indicator of venous return to the heart as it reflects a composite of venous filling pressure, pleural pressure, and transmitted IAP. Transmural CVP and PCWP, and not directly measured CVP and PCWP, should be used as clinical indicators of venous return to the heart in this situation.
authors.affiliation: Servizio di Anestesia e Rianimazione, Azienda Ospedaliera di Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pierri
authors.forename: G
authors.initials: G
authors.lastname: Munegato
authors.forename: L
authors.initials: L
authors.lastname: Carraro
authors.forename: F
authors.initials: F
authors.lastname: Zaccaria
authors.forename: E
authors.initials: E
authors.lastname: Tiso
authors.forename: E F
authors.initials: EF
authors.lastname: Zotti
mesh_terms: D000005:Abdomen / Q000503:physiopathology; D000009:Abdominal Muscles / Q000601:surgery; D000768:Anesthesia, General; D006439:Hemodynamics; D006555:Hernia, Ventral / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D008875:Middle Aged; D011312:Pressure