[The significance of immune island appeared in pleural and peritoneal effusion].
Macrophage surrounded by transformed or untransformed lymphocytes is called immune island. Aimming at this problem, we made a survey of 120 pleural and peritoneal effusion smears with a variety of patients and discovered that this island appeared in 52 (43.3%) cases. The positive results existed in 11 of 14 (79%) cases with tuberculosis and 29 of 60 (48%) cases with malignant diseases. The average number of island on each positive smear (2.0cm x 2.5cm) is 59.6 +/- 12.8 in the former and 39.2 +/- 18.9 in the latter. The mechanism of this phenomenon may be due to the response to foreign stimulus from pathogenic and cancer antigen.
Zhou
D
D
Department of Clinical Laboratory Diagnosis, Changhai Hospital of Second Military Medical University, Shanghai.
Li
C
C
Hui
X
X
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001202:Ascitic Fluid / Q000276:immunology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000276:immunology*; D016066:Pleural Effusion, Malignant / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000276:immunology*