title: Comparing two methods of clinical measurement: a personal history.
abstract: Despite the fundamental importance of measurement in medicine, studies which compare methods of clinical measurement are often analysed inappropriately and may thus come to incorrect conclusions. We explain the problems with the main methods used, notably correlation and regression, and describe the limits of agreement approach which we have proposed. We consider why incorrect methods are so widely used and describe our own experience in bringing this issue to the attention of medical researchers.
authors.affiliation: Department of Public Health Sciences, St George's Hospital Medical School, London, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Bland
authors.forename: D G
authors.initials: DG
authors.lastname: Altman
mesh_terms: D015510:Clinical Medicine / Q000379:methods*; D003627:Data Interpretation, Statistical; D004812:Epidemiologic Methods; D006801:Humans; D010366:Peak Expiratory Flow Rate / Q000502:physiology; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000379:methods