[G-CSF and G-CSF receptor].
Relationship between leucocytosis and G-CSF blood concentration were examined. Increase in blood concentration of G-CSF of surgical patient and dialysis patient with leucocytosis were noticed. Determination of G-CSF receptor on leucocyte was performed by the flow cytometry using biotinylated G-CSF. Modulation of G-CSF receptor on leucocyte at surgery and dialysis was identified in vivo. Studies of G-CSF blood concentration and modulation of G-CSF receptor are useful in analysis of dynamics of leucocyte and analysis of infectious disease.
Saionji
K
K
Department of Clinical Pathology, Juntendo School of Medicine, Tokyo.
Satoh
T
T
Tokuda
H
H
Watanabe
H
H
Ohsaka
A
A
Hiyoshi
K
K
Kurotani
W
W
D016179:Granulocyte Colony-Stimulating Factor / Q000097:blood*; D006801:Humans; D007239:Infections / Q000175:diagnosis; D007964:Leukocytosis / Q000175:diagnosis; D016188:Receptors, Granulocyte Colony-Stimulating Factor / Q000032:analysis*; D006435:Renal Dialysis; D013514:Surgical Procedures, Operative
D016188:Receptors, Granulocyte Colony-Stimulating Factor; D016179:Granulocyte Colony-Stimulating Factor