title: Endodermal sinus tumor arising from a dysgenetic gonad in a 46,XX female combined with müllerian agenesis.
abstract: The occurrence of neoplastic transformation in a dysgenetic gonad of a female with 46,XX karyotype is very rare. Moreover, to our knowledge, a case of endodermal sinus tumor arising from that setting combined with Müllerian agenesis has not been reported. This case suggests the possibility of development of cancer in a dysgenetic ovary of a female even with 46,XX or Müllerian agenesis.
authors.affiliation: Department of Obstetrics and Gynecology, Asan Medical Center, College of Medicine, University of Ulsan, Poongnap-dong, Songpa-gu, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Nam
authors.forename: D G
authors.initials: DG
authors.lastname: Chung
authors.forename: Y M
authors.initials: YM
authors.lastname: Kim
authors.forename: Y T
authors.initials: YT
authors.lastname: Kim
authors.forename: J E
authors.initials: JE
authors.lastname: Mok
mesh_terms: D000328:Adult; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000150:complications* / Q000473:pathology; D005260:Female; D006059:Gonadal Dysgenesis / Q000150:complications* / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D009095:Mullerian Ducts / Q000002:abnormalities*; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications* / Q000473:pathology; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D000509:alpha-Fetoproteins