title: Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain.
abstract: Immunofluorescence studies of rat brain sections demonstrated an exclusive colocalization of the gluconeogenic key enzyme fructose-1,6-bisphosphatase (FBPase) with the astroglial marker glial fibrillary acidic protein, indicating FBPase in brain as an astrocyte-specific enzyme. This conclusion was supported by the presence of FBPase activity in astroglia-rich but not neuron-rich primary cultures derived from rat brain.
authors.affiliation: Physiologisch-chemisches Institut der Universität, Tübingen, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Schmoll
authors.forename: M
authors.initials: M
authors.lastname: Cesar
authors.forename: E
authors.initials: E
authors.lastname: Führmann
authors.forename: B
authors.initials: B
authors.lastname: Hamprecht
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000737:chemistry* / Q000201:enzymology; D001923:Brain Chemistry; D002478:Cells, Cultured; D005455:Fluorescent Antibody Technique; D006597:Fructose-Bisphosphatase / Q000032:analysis*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D051381:Rats
chemical_list: D005904:Glial Fibrillary Acidic Protein; D006597:Fructose-Bisphosphatase