Juvenile chronic lymphocytic leukemia with unusual intracisternal inclusions: an ultrastructural study.
The electron microscopic analysis of intracisternal inclusions in lymphocytes of the bone marrow and peripheral blood in a case of juvenile chronic lymphocytic leukemia is described. These inclusions consist of well-ordered microtubules attached to a central axis. The contribution of electron microscopic analysis in establishing the substructural pattern of these inclusions is discussed.
Escribano
L
L
Servicio de Hematología, Hospital Ramón y Cajal, Madrid, Spain.
Heinrichs
B
B
Villarrubia
J
J
Navas
G
G
Cerveró
C
C
Velasco
J L
JL
Cabezudo
E
E
Roldán
E
E
D000328:Adult; D015703:Antigens, CD / Q000276:immunology; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D002479:Inclusion Bodies / Q000276:immunology / Q000648:ultrastructure*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000145:classification / Q000473:pathology*; D007963:Leukocytes, Mononuclear / Q000166:cytology; D008214:Lymphocytes / Q000276:immunology / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008870:Microtubules / Q000648:ultrastructure*
D015703:Antigens, CD; D007074:Immunoglobulin G