title: Assessment of Yqh translocations.
abstract: Two initially presumed Yqh translocations, one to Xp and another to 21p, were assessed by conventional banding procedures, 5-azacytidine treatment, electron microscopy, and fluorescence in situ hybridisation. While the Yqh nature of the heterochromatic block from Xp was confirmed, this was not the case with the 21ph+ variant. In conclusion, conventional banding techniques are insufficient to diagnose Y;G translocations.
authors.affiliation: Centro Oncológico de Galicia, Laboratorio de Genética, La Coruña, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Fernández
authors.forename: S
authors.initials: S
authors.lastname: Pereira
authors.forename: A
authors.initials: A
authors.lastname: Campos
authors.forename: V
authors.initials: V
authors.lastname: Goyanes
mesh_terms: D001374:Azacitidine; D002891:Chromosomes, Human, Pair 21; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008854:Microscopy, Electron; D014178:Translocation, Genetic; D014960:X Chromosome; D014998:Y Chromosome
chemical_list: D001374:Azacitidine