title: Agglutination of Streptococcus suis by sialic acid-binding lectins.
abstract: The 35 Streptococcus suis capsular-type reference strains as well as 45 field strains of type 2 were tested with sialic acid-binding lectins from Sambucus nigra (SNA I), Triticum vulgaris, Maackia amurensis, Homarus americanus, and Limax flavus. Only types 1, 1/2, 2, 14, 15, and 16 agglutinated with SNA I and/or the T. vulgaris lectin. All field strains agglutinated only with SNA I. Reaction with SNA I was probably due to the sialic acid moiety since it disappeared after sialidase treatment. These results confirm the presence of sialic acid in S. suis with the possible terminal sequence N-acetylneuraminic acid-alpha(2,6)GalNAc.
authors.affiliation: Groupe de Recherche sur les Maladies Infectieuses du Porc, Faculté de médecine vétérinaire, Université de Montréal, St.-Hyacinthe, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Charland
authors.forename: J T
authors.initials: JT
authors.lastname: Kellens
authors.forename: F
authors.initials: F
authors.lastname: Caya
authors.forename: M
authors.initials: M
authors.lastname: Gottschalk
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D001431:Bacteriological Techniques; D001665:Binding Sites; D050260:Carbohydrate Metabolism; D002240:Carbohydrate Sequence; D002241:Carbohydrates / Q000737:chemistry; D006801:Humans; D037102:Lectins / Q000378:metabolism / Q000494:pharmacology*; D008969:Molecular Sequence Data; D012794:Sialic Acids / Q000378:metabolism*; D017011:Streptococcus suis / Q000187:drug effects / Q000378:metabolism* / Q000472:pathogenicity; D013552:Swine; D014774:Virulence
chemical_list: D002241:Carbohydrates; D037102:Lectins; D012794:Sialic Acids