title: Hepatitis A, B and C seroprevalence in Pakistan.
abstract: A cross sectional study was conducted to determine the seroprevalence of Hepatitis A, B, and C virus in healthy Pakistani children. HAV IgG antibody was assayed in 258 subjects and it was found that 94% children by 5 years of age had HAV IgG-antibody. The overall seroprevalence of HAV IgG antibody was 55.8% and IgM 5.3%. HBVsAb levels assayed in 236 healthy children showed a seroprevalence of 2.97%. Similarly, HCV antibody seroprevalence was found to be a low 0.44% in healthy children. HAV is a major cause of Hepatitis, as compared to HBV and HCV which are of low endemicity.
authors.affiliation: Department of Pediatrics, Civil Hospital, Karachi, Pakistan.
authors.forename: M
authors.initials: M
authors.lastname: Agboatwalla
authors.forename: S
authors.initials: S
authors.lastname: Isomura
authors.forename: K
authors.initials: K
authors.lastname: Miyake
authors.forename: T
authors.initials: T
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Morishita
authors.forename: D S
authors.initials: DS
authors.lastname: Akram
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006506:Hepatitis A / Q000097:blood* / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies / Q000097:blood*; D006509:Hepatitis B / Q000097:blood* / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D006510:Hepatitis B Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000097:blood* / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology; D018937:Hepatitis C Antibodies; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010154:Pakistan / Q000453:epidemiology; D015995:Prevalence
chemical_list: D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M