[An electron radioautographic study of the dynamic decrease in the level of RNA synthesis in human brain cells at different times after death].
The above study is performed in neurons, oligodendrocytes and capillary endotheliocytes of human brain 4-13 hours after death. Brain biopsies after the surgery and early necropsies served as the material. RNA synthesis in some neurons and glial cells is retained to some degree 8-13 hours after death. Oligodendrocytes are more and neurons less resistant. Grave disturbances of the CNS microcirculation is the obstacle to reversibility of destructive processes.
Tumanov
V P
VP
Zakharova
O A
OA
Gel'fand
V B
VB
D001344:Autopsy; D001345:Autoradiography; D001706:Biopsy; D001923:Brain Chemistry; D001926:Brain Death / Q000378:metabolism* / Q000473:pathology; D002196:Capillaries / Q000378:metabolism / Q000648:ultrastructure; D002531:Cerebellum / Q000098:blood supply / Q000378:metabolism* / Q000648:ultrastructure; D002540:Cerebral Cortex / Q000098:blood supply / Q000378:metabolism* / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D009474:Neurons / Q000378:metabolism / Q000648:ultrastructure; D009836:Oligodendroglia / Q000378:metabolism / Q000648:ultrastructure; D012313:RNA / Q000096:biosynthesis*; D013997:Time Factors
D012313:RNA