[The effect of hemosorption on the glycoprotein concentration of the blood serum in inflammatory diseases of the large intestine].
71 patients with nonspecific diseases of the colon were examined before and after hemosorption for concentrations of seromucoid, orosomucoid, immunoglobulins G,M,A, C3 and C4 complement component fractions, haptoglobin, ceruloplasmin, alpha 1-antitrypsin, C-reactive protein, properdin, transferrin. It was found that hemosorption results in lowering of all the above concentrations in nonspecific ulcerative colitis, except seromucoid and orosomucoid in moderate and acute colitis. In response to hemosorption serum glycoproteins levels varied with the disease severity, its duration and metabolic activity of the liver. Concentrations of seromucoids, orosomucoid, alpha 1-antitrypsin changed in correlation with clinical manifestations of colon inflammation and may serve as criteria of hemosorption efficacy.
Ivanov
A F
AF
Eroshkina
T D
TD
Fomin
S A
SA
Musin
I I
II
Chirkin
V V
VV
D000209:Acute-Phase Proteins / Q000032:analysis; D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000097:blood* / Q000628:therapy*; D003424:Crohn Disease / Q000097:blood* / Q000628:therapy*; D005260:Female; D006023:Glycoproteins / Q000097:blood*; D006464:Hemoperfusion; D006801:Humans; D007120:Immunochemistry; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D000209:Acute-Phase Proteins; D006023:Glycoproteins