[Metabolic acidosis under an acid load and the role of the respiratory system in its compensation in middle-aged and elderly persons].
30 healthy 60- to 89-year-old subjects and 20 young ones (20 to 31 years) were given orally ammonium chloride 125 mg/kg. The signs of subsequent metabolic acidosis were more obvious in older subjects and they lasted longer. In young subjects, the intake of ammonium chloride induced a considerable hyperventilation.
Korkushko
O V
OV
Ivanov
L A
LA
Belyĭ
A A
AA
D000136:Acid-Base Equilibrium / Q000187:drug effects / Q000502:physiology; D000138:Acidosis / Q000139:chemically induced / Q000503:physiopathology*; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000643:Ammonium Chloride / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012119:Respiration / Q000187:drug effects / Q000502:physiology; D012137:Respiratory System / Q000187:drug effects / Q000503:physiopathology*; D013997:Time Factors
D000643:Ammonium Chloride