title: A clinical trial comparing two doses of oral temazepam for sedation of paediatric dental patients.
abstract: A study was carried out to compare the effectiveness of two doses of temazepam elixir for the behaviour management of paediatric dental patients. Twenty-two children aged 2-5 years (mean 4.06 years), classified as ASA Class I and II (American Society of Anesthesiologists Classification), were assigned to receive either 0.3 or 0.5 mg/kg temazepam elixir in a double-blind randomized cross-over study. All treatment sessions were videotaped and rated independently by three paediatric dentists for the degree of crying, movement, sleep and overall behaviour at 15-minute intervals while being treated. The results showed no statistically significant differences between the two doses.
authors.affiliation: Department of Paediatric Dentistry, Leeds Dental Institute, England.
authors.forename: K M
authors.initials: KM
authors.lastname: el Magboul
authors.forename: E A
authors.initials: EA
authors.lastname: O'Sullivan
authors.forename: M E
authors.initials: ME
authors.lastname: Curzon
mesh_terms: D000766:Anesthesia, Dental / Q000379:methods*; D014151:Anti-Anxiety Agents / Q000008:administration & dosage*; D016009:Chi-Square Distribution; D002652:Child Behavior; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods*; D018592:Cross-Over Studies; D019140:Dental Care for Children / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D015588:Observer Variation; D015203:Reproducibility of Results; D013693:Temazepam / Q000008:administration & dosage*
chemical_list: D014151:Anti-Anxiety Agents; D013693:Temazepam