Activation of xenobiotics into free radicals by prostaglandin-H-synthase and by rat liver microsomes.
Mannaioni
P F
PF
Department of Preclinical and Clinical Pharmacology, Florence University, Italy.
Di Bello
M G
MG
Raspanti
S
S
Mugnai
L
L
Romano
V
V
Masini
E
E
D000818:Animals; D003042:Cocaine / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism; D006636:Histamine Release / Q000187:drug effects; D008315:Malondialdehyde / Q000378:metabolism*; D008407:Mast Cells / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D008691:Methadone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000378:metabolism*; D009020:Morphine / Q000494:pharmacology; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D015262:Xenobiotics / Q000378:metabolism*
D005609:Free Radicals; D015262:Xenobiotics; D008315:Malondialdehyde; D009020:Morphine; D011451:Prostaglandin-Endoperoxide Synthases; D003042:Cocaine; D008691:Methadone