title: Hyponatraemia and hyperkalaemia in acute pyelonephritis without urinary tract anomalies.
abstract: Three children with severe hyponatraemia and hyperkalaemia associated with acute pyelonephritis are reported. All were very young male infants in a poor general condition and seriously dehydrated. Diagnostic procedures did not detect obstructive uropathy or vesico-ureteric reflux.
  
  
  CONCLUSIONS
  Hyponatraemia and hyperkalaemia occurs in young infants with severe acute pyelonephritis in the absence of obstructive uropathy or vesico-ureteric reflux. The severe inflammation of the kidney itself may explain the electrolyte disturbance by a transient resistance of the distal tubule to aldosterone.
authors.affiliation: Zentrum für Kinderheilkunde, Giessen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Gerigk
authors.forename: R
authors.initials: R
authors.lastname: Glanzmann
authors.forename: W
authors.initials: W
authors.lastname: Rascher
authors.forename: H E
authors.initials: HE
authors.lastname: Gnehm
mesh_terms: D000208:Acute Disease; D003937:Diagnosis, Differential; D006801:Humans; D007008:Hypokalemia / Q000097:blood* / Q000209:etiology; D007010:Hyponatremia / Q000097:blood* / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011704:Pyelonephritis / Q000097:blood* / Q000209:etiology; D012189:Retrospective Studies; D014551:Urinary Tract / Q000002:abnormalities; D014718:Vesico-Ureteral Reflux / Q000097:blood / Q000150:complications