title: A new method for early diagnosis of carcinoma in bile duct-sonography of common bile duct before and after injection of ceosunin.
abstract: 42 cases of dilatation (7-15 mm) of extrahepatic bile duct after ceosunin injection (cholagogic method) were observed ultrasonographically. Among the 18 cases of testified obstructive lesions of the bile duct, 13 (72%) showed widening of the bile duct with an increase of calibre from 9.8 mm to 11.7 mm, 3 (16%) had no obvious change, and 2 (12%) shrank. Among the 24 cases of non-obstruction 22 (92%) shrank with a decrease calibre from 9.6 mm to 6.3 mm, and 2 (8%) showed no obvious change. After receiving cholagogue, 9 cases of periampullary carcinoma in the obstructive group were confronted with widening of the bile duct calibre. After longitudinal and transverse rotation scanning method was used, 8 of the 9 cases had their tumor mass visualized. Combined cholagogic and rotation scanning methods raised the lesion manifestation rate of lower bile duct from 41% to 88%. A dilated bile duct unable to show shrinkage of calibre after cholagogue injection is believed to be a criterion for judging the presence of a suspicious case of bile duct obstruction. This criterion has a sensitivity of 89%, specificity of 92%, and accuracy of 90%.
authors.affiliation: College of Clinical Oncology, Beijing Medical University.
authors.forename: M
authors.initials: M
authors.lastname: Chen
authors.forename: B
authors.initials: B
authors.lastname: Dong
authors.forename: Q
authors.initials: Q
authors.lastname: Zhu
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: B
authors.initials: B
authors.lastname: Wang
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: C
authors.initials: C
authors.lastname: Kiyosi
authors.forename: S
authors.initials: S
authors.lastname: Yukihiko
authors.forename: K
authors.initials: K
authors.lastname: Riwa
authors.forename: F
authors.initials: F
authors.lastname: Nobuyuk
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater / Q000000981:diagnostic imaging*; D002756:Cholagogues and Choleretics; D003138:Common Bile Duct Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005765:Gastrointestinal Agents; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods
chemical_list: D002756:Cholagogues and Choleretics; D005765:Gastrointestinal Agents