Correlation between micturitional urethral pressure profile and pressure-flow criteria in bladder outlet obstruction.
OBJECTIVE
We correlate micturitional urethral pressure profilometry with pressure-flow diagnoses of outlet obstruction.


METHODS
Urodynamic evaluation was done of 86 consecutive men with voiding symptoms. Obstruction criteria were a micturitional urethral pressure profile (MUPP) gradient greater than 5 cm. water, Schäfer's linear passive urethral resistance relation (PURR) greater than grade 1 and Abrams-Griffiths nomogram.


RESULTS
Interpretable results were completed in 99% of the patients undergoing MUPP and 60% undergoing pressure-flow studies (p < 0.00001). MUPP diagnosis agreed with PURR (p = 0.0015) and Abrams-Griffiths nomogram results (p = 0.00004). MUPP gradients correlated well with PURR (r = 0.70, p < 0.00001). Using optimum cutoff values (11 cm. water), the sensitivity of MUPP was 83%, specificity 82% and positive predictive value 94%.


CONCLUSIONS
MUPP correlates well with and yields interpretable results more often than pressure-flow studies.
DuBeau
C E
CE
Urology Division, Brockton/West Roxbury Veterans Administration Medical Center, Boston, Massachusetts, USA.
Sullivan
M P
MP
Cravalho
E
E
Resnick
N M
NM
Yalla
S V
SV
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011470:Prostatic Hyperplasia / Q000150:complications / Q000503:physiopathology*; D012372:ROC Curve; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000503:physiopathology*; D014554:Urination / Q000502:physiology; D014563:Urodynamics / Q000502:physiology*