Investigation of the effect of poorly controlled diabetes mellitus on erythrocyte life.
Erythrocyte half-life (Et-1/2) has been measured in 11 patients with poorly controlled blood sugar levels and compared with a normal control group to determine whether decreased red cell deformability, which occurs in diabetic patients, causes shortening of erythrocyte life or not. No difference was seen (Et-1/2 = 28.1 days in diabetic patients and 28.5 days in controls). There was also no correlation between Et-1/2 and glycosylated hemoglobin (HbA1) levels. It has been concluded that poorly controlled diabetes mellitus has no effect upon erythrocyte life.
Sayinalp
S
S
Department of Internal Medicine, Hacettepe University, School of Medicine, Ankara, Turkey.
Sözen
T
T
Usman
A
A
Dündar
S
S
D001786:Blood Glucose / Q000378:metabolism*; D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D004905:Erythrocyte Aging; D004907:Erythrocyte Deformability; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012727:Sex Characteristics
D001786:Blood Glucose; D006442:Glycated Hemoglobin