title: 6-(4-pyridinyl)-1H-1,2,3-triazolo[4,5-d]-pyrimidin-4(5H)-one: a structurally novel competitive AMPA receptor antagonist.
authors.affiliation: Department of Medicinal Chemistry, Sanofi Winthrop Inc., Collegeville, Pennsylvania 19426.
authors.forename: C
authors.initials: C
authors.lastname: Subramanyam
authors.forename: B
authors.initials: B
authors.lastname: Ault
authors.forename: D
authors.initials: D
authors.lastname: Sawutz
authors.forename: E R
authors.initials: ER
authors.lastname: Bacon
authors.forename: B
authors.initials: B
authors.lastname: Singh
authors.forename: P O
authors.initials: PO
authors.lastname: Pennock
authors.forename: M D
authors.initials: MD
authors.lastname: Kelly
authors.forename: M
authors.initials: M
authors.lastname: Kraynak
authors.forename: D
authors.initials: D
authors.lastname: Krafte
authors.forename: A
authors.initials: A
authors.lastname: Treasurywala
mesh_terms: D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D011744:Pyrimidinones / Q000737:chemistry / Q000494:pharmacology*; D018091:Receptors, AMPA / Q000037:antagonists & inhibitors*; D014230:Triazoles / Q000737:chemistry / Q000494:pharmacology*; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid / Q000378:metabolism
chemical_list: C092097:6-(4-pyridinyl)-1H-1,2,3-triazolo(4,5-d)pyrimidin-4(5H)-one; D011744:Pyrimidinones; D018091:Receptors, AMPA; D014230:Triazoles; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid