der(1;15)(q10;10): a nonrandom chromosomal abnormality of myeloid neoplasia.
The occurrence of an unusual karyotypic abnormality der(1;15)(q10;q10) is reported in three patients, one with acute megakaryoblastic leukemia and two with myelodysplastic syndrome. A literature review shows that this cytogenetic abnormality is a rare but nonrandom change in myeloid neoplasia/neoplasia.
Wong
K F
KF
Section of Cytogenetics, Anderson Cancer Center, Houston, Texas 77030, USA.
Hayes
K J
KJ
Glassman
A B
AB
D000368:Aged; D002675:Child, Preschool; D002878:Chromosomes, Human, Pair 1; D002884:Chromosomes, Human, Pair 15; D005260:Female; D006801:Humans; D007621:Karyotyping; D007947:Leukemia, Megakaryoblastic, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D014178:Translocation, Genetic