In vitro release of ketoprofren and ibuprofen from viscoelastic gels.
Gels of viscoelastic type formed by isopropylmyristate, Tween 60 and water are prepared in the presence or not of antiinflammatory agents such as Ketoprofen and Ibuprofen. In vitro release studies evaluated by using an absorption simulator were performed in order to determine the diffusion rate of these drugs from prepared gels. The obtained results showed a higher rate diffusion compared with the release from commercial products containing these drugs.
Bajardi
M
M
Dipartimento di Chimica e Tecnologie Farmaceutiche, Università di Palermo, Italy.
Pitarresi
G
G
Roccaro
A
A
Giammona
G
G
Palazzo
S
S
D004548:Elasticity; D005079:Excipients; D005782:Gels; D007052:Ibuprofen / Q000008:administration & dosage* / Q000737:chemistry; D007660:Ketoprofen / Q000008:administration & dosage* / Q000737:chemistry; D014783:Viscosity
D005079:Excipients; D005782:Gels; D007660:Ketoprofen; D007052:Ibuprofen