title: Copper-induced changes in the urea uptake and urease activity in the cyanobacteria Anabaena doliolum and Anacystis nidulans: interaction with sulphur containing amino acids.
abstract: Copper-induced changes in the urea uptake and urease activity have been investigated in the cyanobacteria Anabaena doliolum and Anacystis nidulans. Copper, at and above 5 mumol/L concentration, inhibited urea uptake and urease activity systems in both the cyanobacteria in a concentration dependent manner. However, the urea uptake and urease activity systems in A. nidulans appeared slightly more tolerant to copper than than of A. doliolum. The inhibitory effect of copper on urea uptake and urease activity was mitigated by sulphur containing amino acids (cystine and cysteine), however, methionine could not do so, indicating the involvement of sulfhydryl (-SH) groups in the assimilation of urea in cyanobacteria.
authors.affiliation: Department of Microbiology, North Maharashtra University, Jalgaon, India.
authors.forename: S
authors.initials: S
authors.lastname: Singh
authors.forename: B B
authors.initials: BB
authors.lastname: Singh
authors.forename: P S
authors.initials: PS
authors.lastname: Bisen
mesh_terms: D000603:Amino Acids, Sulfur / Q000494:pharmacology; D017033:Anabaena / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D003300:Copper / Q000494:pharmacology*; D000458:Cyanobacteria / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D014508:Urea / Q000493:pharmacokinetics*; D014510:Urease / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000603:Amino Acids, Sulfur; D003300:Copper; D014508:Urea; D014510:Urease