Cefotaxime versus ceftriaxone for the treatment of nosocomial pneumonia. Results of a multicenter study.
Third-generation cephalosporins are the drugs of choice for serious nosocomial pneumonia; however, the recommended dosages are controversial. Our study compared two of these cephalosporins and showed that 2 g cefotaxime every 12 h and 4 g ceftriaxone once daily or 2 g every 12 h proved to be effective therapies for these chest indications.
Shah
P M
PM
Centre of Internal Medicine/Infectious Diseases, University Hospital, Frankfurt, Germany.
Stille
W
W
D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000008:administration & dosage / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use*; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D016896:Treatment Outcome
D002511:Cephalosporins; D002443:Ceftriaxone; D002439:Cefotaxime