title: Response to interferon therapy in children with chronic hepatitis C.
abstract: We evaluated the effect of interferon therapy and investigated factors that may influence the outcome in 18 children with chronic hepatitis C. A complete response was obtained in 10 children (56%). The titer for pretreatment serum virus ribonucleic acid (< or = 10(7) copies/ml) was correlated significantly with a complete response to therapy.
authors.affiliation: Department of Pediatrics, National Defense Medical College, Saitama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fujisawa
authors.forename: A
authors.initials: A
authors.lastname: Inui
authors.forename: T
authors.initials: T
authors.lastname: Ohkawa
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: Y
authors.initials: Y
authors.lastname: Miyakawa
authors.forename: M
authors.initials: M
authors.lastname: Onoue
mesh_terms: D000410:Alanine Transaminase / Q000097:blood / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005838:Genotype; D006526:Hepatitis C / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007075:Immunoglobulin M; D007372:Interferons / Q000627:therapeutic use*; D008099:Liver / Q000201:enzymology / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D016133:Polymerase Chain Reaction; D012367:RNA, Viral; D016896:Treatment Outcome
chemical_list: D007075:Immunoglobulin M; D012367:RNA, Viral; D007372:Interferons; D000410:Alanine Transaminase