title: Reversal of atropine-resistant atrioventricular block with intravenous aminophylline in the early phase of inferior wall acute myocardial infarction following treatment with streptokinase.
abstract: We report three patients with acute inferior myocardial infarction treated with aspirin (150 mg) and streptokinase (1.5 MU over 60 min), who developed atropine-resistant bradyarrhythmias during or immediately following streptokinase. The bradyarrhythmias responded to aminophylline, thus avoiding the need for temporary pacing.
authors.affiliation: Department of Cardiology, Southmead Hospital, Bristol, U.K.
authors.forename: J
authors.initials: J
authors.lastname: Goodfellow
authors.forename: P R
authors.initials: PR
authors.lastname: Walker
mesh_terms: D000368:Aged; D000628:Aminophylline / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use*; D004351:Drug Resistance; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000628:Aminophylline; D001285:Atropine; D013300:Streptokinase