title: Modification of coronary artery disease using antithrombotic therapy.
abstract: I review some of the literature concerning antithrombotic therapy in coronary artery disease. The beneficial effects shown are compatible with the unitary hypothesis of thrombosis as a fundamental of cardiovascular risk. The therapeutic approach is limited by the haemorrhagic risk produced by most antithrombotic therapies. A search should therefore be made for antithrombotic therapies without this risk, of which serotonin antagonism appears to be the most promising at present.
authors.affiliation: Academic Unit of Cardiovascular Medicine, Charing Cross and Westminister Medical School, London, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Drake-Holland
mesh_terms: D000818:Animals; D003327:Coronary Disease / Q000188:drug therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D012307:Risk Factors
chemical_list: D005343:Fibrinolytic Agents