title: [A successfully treated case of thoracoabdominal aortic aneurysm complicated with the coagulation disorder].
abstract: We could performed the safe operation for thoracoabdominal aortic aneurysm complicated with pre-DIC. A diagnosis of pre-DIC was made by laboratory data. Low heparin pretreatment was performed for the short term because we presumed the cause for pre-DIC was thromboses in aneurysm. That treatment was effective for the temporal remission of pre-DIC. In addition, during partial ECC low heparin (1 mg/kg) and nafamostat mesilate (2 mg/kg/h) were used. As a result, during and after the operation blood loss was a little. In summary heparin pretreatment is useful therapy for DIC and pre-DIC in aortic aneurysm patients.
authors.affiliation: Department of Cardiovascular Surgery, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ohsawa
authors.forename: M
authors.initials: M
authors.lastname: Tsubota
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: M
authors.initials: M
authors.lastname: Seki
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage; D000991:Antithrombins / Q000008:administration & dosage; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000150:complications / Q000601:surgery*; D001550:Benzamidines; D001807:Blood Vessel Prosthesis; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006146:Guanidines / Q000008:administration & dosage; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D011292:Premedication
chemical_list: D000925:Anticoagulants; D000991:Antithrombins; D001550:Benzamidines; D006146:Guanidines; D006493:Heparin; C032855:nafamostat