title: [A trial of the use of finasteride and terazosin in patients with benign prostatic hyperplasia].
abstract: 94 patients with obstructive urination due to benign prostatic hyperplasia received finasteride (proscar), inhibitor of 5 alpha-reductase, in a single dose 5 mg and terazosine, alpha 1 adrenoblocker, in a daily dose of 9.7 mg/day. The follow-up averaged 16.1 months. As shown by overall score of the symptoms and quality of life, rectal and ultrasonic examinations, uroflowmetry, the prostate decreased by 17%, on the average in 72% of the patients. Subjectively, urination has also improved. Maximal flow rate elevated by 55% in the majority of patients. Combination of finasterine with terazosine is well tolerated and proved optimal as a conservative therapy in patients with obstructive urination as a result of benign prostatic hyperplasia.
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Pushkar'
authors.forename: D V
authors.initials: DV
authors.lastname: Kosko
authors.forename: O B
authors.initials: OB
authors.lastname: Loran
authors.forename: Ia D
authors.initials: IaD
authors.lastname: Kan
authors.forename: I M
authors.initials: IM
authors.lastname: Sapozhnikov
authors.forename: K P
authors.initials: KP
authors.lastname: Tevlin
mesh_terms: D058891:5-alpha Reductase Inhibitors; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000368:Aged; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004359:Drug Therapy, Combination; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D018120:Finasteride / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011224:Prazosin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011470:Prostatic Hyperplasia / Q000188:drug therapy*; D012074:Remission Induction; D013997:Time Factors
chemical_list: D058891:5-alpha Reductase Inhibitors; D000317:Adrenergic alpha-Antagonists; D003692:Delayed-Action Preparations; D004791:Enzyme Inhibitors; D018120:Finasteride; C041226:Terazosin; D011224:Prazosin
vernacular_title: Opyt primeneniia finasterida i terazosina u bol'nykh s dobrokachestvennoĭ giperplazieĭ prostaty.