Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
The crystal structure of the haemopexin-like C-terminal domain of gelatinase A reveals that it is a four-bladed beta-propeller protein. The four blades are arranged around a channel-like opening in which Ca2+ and a Na-Cl+ ion pair are bound.
Libson
A M
AM
Gittis
A G
AG
Collier
I E
IE
Marmer
B L
BL
Goldberg
G I
GI
Lattman
E E
EE
D000595:Amino Acid Sequence; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism; D002412:Cations / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism; D003461:Crystallography; D018093:Gelatinases / Q000737:chemistry*; D006466:Hemopexin / Q000737:chemistry; D007473:Ion Channels / Q000737:chemistry; D020778:Matrix Metalloproteinase 2; D008666:Metalloendopeptidases / Q000737:chemistry*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry*; D011392:Proline / Q000737:chemistry; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D012964:Sodium / Q000378:metabolism
D002412:Cations; D002712:Chlorides; D007473:Ion Channels; D010446:Peptide Fragments; D006466:Hemopexin; D011392:Proline; D012964:Sodium; D018093:Gelatinases; D008666:Metalloendopeptidases; D020778:Matrix Metalloproteinase 2; D002118:Calcium