[A neurophysiological assessment of the effect of trimetidon on brain function in the cat].
Stimulation of the cat brain mesencephalic RF augmented the high-frequency activity in control animals and failed to do so after 4-oxopyrimidine administration. These and some other EEG changes suggest presence of an anxiolytic component in the trimethidone, the latter thus being similar by its effect to 1,4-benzodiazepines and endogenous pyrimidines.
Voĭnov
V B
VB
Belova
E I
EI
Kiroĭ
V N
VN
Riabukhin
Iu I
IuI
D000703:Analog-Digital Conversion; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000502:physiology; D002415:Cats; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000187:drug effects / Q000295:instrumentation; D008838:Microcomputers; D011619:Psychotropic Drugs / Q000494:pharmacology*; D011743:Pyrimidines / Q000494:pharmacology*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D013997:Time Factors
D011619:Psychotropic Drugs; D011743:Pyrimidines; C096687:trimetidon
Neĭrofiziologicheskaia otsenka vliianiia trimetidona na funktsional'noe sostoianie mozga koshki.