title: A case report of colonic ileus due to eosinophilic nodular lesions caused by Gnathostoma doloresi infection.
abstract: Gnathostomiasis is primarily a disease of the skin characterized as creeping eruption or mobile erythema. However, larval Gnathostoma sometimes migrate into an unexpected site to elicit serious illness. Here we describe a case of colonic ileus caused by Gnathostoma doloresi. The patient was a 57-year-old man living in Miyazaki Prefecture, Japan, which is known as an area endemic for this parasite. One week after having eaten a few slices of the flesh of a snake (Agkistrodon halys), he developed severe abdominal pain. An abdominal radiograph revealed multiple gas-fluid levels with a distended bowel of an inverted U shape. A barium enema revealed a tumor in the ascending colon near the hepatic flexure that was surgically removed by simple colonic resection. An oblique section of a parasite surrounded by massive infiltration of eosinophils was found by postoperative histopathologic examination. The entire body of the advanced third-stage larva of G. doloresi was dissected from a specimen-embedded paraffin block.
authors.affiliation: Second Department of Pathology, Miyazaki Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Seguchi
authors.forename: M
authors.initials: M
authors.lastname: Matsuno
authors.forename: H
authors.initials: H
authors.lastname: Kataoka
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Maruyama
authors.forename: H
authors.initials: H
authors.lastname: Itoh
authors.forename: M
authors.initials: M
authors.lastname: Koono
authors.forename: Y
authors.initials: Y
authors.lastname: Nawa
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis / Q000276:immunology; D000947:Antigens, Helminth / Q000276:immunology; D003108:Colonic Diseases / Q000209:etiology* / Q000276:immunology / Q000469:parasitology; D004797:Enzyme-Linked Immunosorbent Assay; D004804:Eosinophils / Q000276:immunology*; D016266:Food Parasitology; D006039:Gnathostoma / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology* / Q000276:immunology / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D017205:Spirurida Infections / Q000150:complications* / Q000276:immunology / Q000469:parasitology
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth