[Reduction of coronary events: what are the possible mechanisms?].
Clinical studies have shown that lipid-lowering therapy reduces the incidence of cardiovascular events. However, lesion regression is relatively minor and does not seem to reflect the clear improvement in clinical events. Normalization of the lipid profile correlates with a reduction in atheromatous plaque complications. The responsible mechanisms for such reduction are diverse and are the subject of extensive research.
Badimón
L
L
Departamento de Patología Molecular y Terapéutica, Hospital de la Santa Creu i Sant Pau, UAB, Barcelona.
Pueyo Palazón
C
C
Varela Villén
O
O
Viñals Izquierdo
M
M
D000818:Animals; D002784:Cholesterol / Q000097:blood; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D004730:Endothelium, Vascular / Q000473:pathology; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008833:Microcirculation; D012307:Risk Factors; D013552:Swine
D000960:Hypolipidemic Agents; D008055:Lipids; D002784:Cholesterol
Reducción de los eventos coronarios: cuáles son los posibles mecanismos?