[Effects of intraperitoneal insufflation on hematogenous seeding of abdominal infections. Preliminary results of an experimental study in rats].
Most laparoscopic procedures require the creation of a pneumoperitoneum. In order to evaluate the potential hazards of bacteriemia related to insufflation, we conducted a study in the rat. Two groups of 20 Wistar rats were used for this study. Peritonitis was induced by opening the terminal ileum. Twenty-four hours later, 20 rats were insufflated at a mean pressure of 6 mm Hg (Group I). After one hour of insufflation, an hemoculture was performed via direct intracardiac puncture and in the other group of 20 non-insufflated rats (Group NI). Five of the 18 hemoculture were positive in the Gr. I (27.7%) and 6 out of 20 in the Gr. NI (30%) (chi 2 = 0.238 p = 0.62 non significant difference). These results suggest that insufflation does not facilitate hematogenous dissemination of bacteria from intraperitoneal sepsis in this animal model.
Dugue
L
L
Service de Chirurgie, Hôpital Saint-Louis, Paris.
Fritsch
S
S
Felten
A
A
Gossot
D
D
Colomer
S
S
Celerier
M
M
Lagrange
P
P
Revillon
Y
Y
D000818:Animals; D016470:Bacteremia / Q000209:etiology* / Q000382:microbiology; D004195:Disease Models, Animal; D004756:Enterobacteriaceae Infections / Q000209:etiology* / Q000382:microbiology; D007327:Insufflation / Q000009:adverse effects*; D008297:Male; D010538:Peritonitis / Q000601:surgery*; D011027:Pneumoperitoneum / Q000209:etiology* / Q000382:microbiology; D051381:Rats; D017208:Rats, Wistar
Effets de l'insufflation intra-péritonéale sur la dissémination hématogène des infections abdominales. Résultats préliminaires d'une étude expérimentale chez le rat.