Bioavailability of buserelin and gonadorelin in suspensions.
There have been determined parameters defining biological availability of gonadorelin and buserelin marked 125 J. Hormonal preparations were hypodermically administered to the rats in suspensions containing zinc ions of the molar ratio of the hormone: zinc 1:5. It has been stated that buserelin in suspension is better available to an organism than gonadorelin .
Dolińska
B
B
Department of Applied Pharmacy and Drug Technology, Silesian Medical Academy, Sosnowiec, Poland.
Ryszka
F
F
Szulc
B
B
D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002064:Buserelin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D051381:Rats; D017208:Rats, Wistar; D013535:Suspensions
D018931:Antineoplastic Agents, Hormonal; D013535:Suspensions; D007987:Gonadotropin-Releasing Hormone; D002064:Buserelin