Cerebral gigantism (Sotos' syndrome). A rare cause of delayed walking and awkward gait.
A case history of an 8-year-old girl with cerebral gigantism (Sotos' syndrome) has been presented. Throughout her life, this child has demonstrated all of the common features of Sotos' syndrome including large size at birth, excessive growth during childhood, dysmorphic craniofacial features, delay in motor and speech development, generalized clumsiness, and awkward gait. Family history was contributory with delays in early language development and the possibility that the child's father had Sotos' syndrome. When evaluating a pediatric patient for pes planus, delayed walking, and gait problems, the practitioner should consider the entire clinical profile and unusual etiologies.
Sobel
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New York College of Podiatric Medicine, NY 10035, USA.
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D001921:Brain / Q000002:abnormalities*; D002648:Child; D005260:Female; D005684:Gait; D005877:Gigantism / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009069:Movement Disorders / Q000209:etiology* / Q000503:physiopathology; D013577:Syndrome; D016138:Walking