title: Effect of sodium hexametaphosphate on dental calculus formation in dogs.
abstract: A series of studies was conducted to identify a practical measure for preventing dental calculus formation in dogs. The studies involved a colony of 27 Beagles that received an initial dental prophylaxis. The dogs were then stratified on the basis of their normal rate of calculus formation and randomly assigned to parallel groups within each strata. During 4-week test periods, a variety of experimental regimens were instituted, followed by clinical assessments of calculus. Major observations were that a crystal growth inhibitor, soluble pyrophosphate, incorporated into a dry dog food modestly reduced calculus formation when used at high concentration; anticalculus effects attributable to this agent were significant (P < 0.05) only when it was used as a surface coating; the coating of dry dog chow or plain biscuits with a calcium sequestrant, sodium hexametaphosphate (HMP), provided the greatest benefit and resulted in significant (P < 0.05) reductions in calculus formation of about 60 to 80%, depending on the dosage regimen; and the feeding of a single daily snack of 2 HMP-coated plain biscuits (0.6% HMP) decreased calculus formation by nearly 80%. We concluded that the coating of dry dog chow or plain dog biscuits with HMP is an effective means of reducing calculus formation in dogs.
authors.affiliation: Oral Health Research Institute, School of Dentistry, Indiana University, Indianapolis 46202, USA.
authors.forename: G K
authors.initials: GK
authors.lastname: Stookey
authors.forename: J M
authors.initials: JM
authors.lastname: Warrick
authors.forename: L L
authors.initials: LL
authors.lastname: Miller
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D003728:Dental Calculus / Q000503:physiopathology / Q000517:prevention & control / Q000662:veterinary*; D004032:Diet; D004283:Dog Diseases; D004285:Dogs; D010710:Phosphates / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D010710:Phosphates; C009285:sodium polymetaphosphate