title: DSM-IV and the disappearance of agoraphobia without a history of panic disorder: new data on a controversial diagnosis.
abstract: OBJECTIVE
  This analysis describes subjects who met rigorous criteria for DSM-III-R agoraphobia without a history of panic disorder and makes inferences from these data regarding relationships among agoraphobia without a history of panic disorder, panic disorder, and panic disorder with agoraphobia.
  
  
  METHODS
  Twenty-six subjects (seven men and 19 women) with agoraphobia without a history of panic disorder were identified from among 711 subjects recruited for a multicenter, longitudinal anxiety disorder study. Narrative transcripts prepared by raters from study evaluations were coded for limited symptom attacks, situational panic, catastrophic cognitions, and possible precipitants and stressors, course, and somatic and psychosocial treatments received.
  
  
  RESULTS
  Sixty-five percent of the subjects reported experiences consistent with situational panic attacks, and 57% had definite or probable limited symptom attacks; these attacks usually preceded or appeared at the same time as avoidance behavior. Eighty-one percent had catastrophic cognitions associated with agoraphobia. Twenty-six percent reported a likely precipitating factor for symptom onset, and 30% reported a definite or probable major life stressor within 6 months before symptom onset. Cognitive-behavioral treatments were relatively infrequently used. Course was relatively unchanged across the follow-up period.
  
  
  CONCLUSIONS
  These data support a view of agoraphobia without a history of panic disorder on a continuum with uncomplicated panic disorder and with panic disorder and agoraphobia, rather than as a separate diagnosis.
authors.affiliation: Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Goisman
authors.forename: M G
authors.initials: MG
authors.lastname: Warshaw
authors.forename: G S
authors.initials: GS
authors.lastname: Steketee
authors.forename: E J
authors.initials: EJ
authors.lastname: Fierman
authors.forename: M P
authors.initials: MP
authors.lastname: Rogers
authors.forename: I
authors.initials: I
authors.lastname: Goldenberg
authors.forename: N J
authors.initials: NJ
authors.lastname: Weinshenker
authors.forename: R G
authors.initials: RG
authors.lastname: Vasile
authors.forename: M B
authors.initials: MB
authors.lastname: Keller
mesh_terms: D000328:Adult; D000379:Agoraphobia / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology; D015897:Comorbidity; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D009626:Terminology as Topic