title: Successful surgical management of emphysematous giant bullae accompanied by severe bronchial asthma: report of a case.
abstract: The surgical treatment of emphysematous lung bullae is usually contraindicated in patients with severe bronchial asthma. However, we recently encountered a patient who required surgery due to the development of respiratory distress despite treatment with bronchodilators and low-dose prednisolone (5 mg/day). During the first operation, bronchospasm occurred with anesthesia. After suppression of the asthmatic symptoms for 2 weeks with high-dose prednisolone (25 mg/day), the giant bullae could be resected safely. Thus, the preoperative resolution of asthma to decrease the probability of an attack is indispensable for such patients.
authors.affiliation: Second Department of Surgery, Gunma University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: I
authors.initials: I
authors.lastname: Yoshida
authors.forename: A
authors.initials: A
authors.lastname: Ohtaki
authors.forename: Y
authors.initials: Y
authors.lastname: Otani
authors.forename: K
authors.initials: K
authors.lastname: Sakata
authors.forename: Y
authors.initials: Y
authors.lastname: Morishita
mesh_terms: D000328:Adult; D000628:Aminophylline / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001249:Asthma / Q000000981:diagnostic imaging / Q000601:surgery*; D001986:Bronchial Spasm / Q000517:prevention & control; D001993:Bronchodilator Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000031:analogs & derivatives; D007431:Intraoperative Complications / Q000517:prevention & control; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D011292:Premedication; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents; D000628:Aminophylline; D011239:Prednisolone; C007133:hydrocortisone hemisuccinate; D006854:Hydrocortisone