The diagnosis and treatment of breast cancer.
There have been several new developments in breast cancer research. Investigators are closer to identifying the breast cancer gene, which may aid in the diagnosis and treatment of the disease. The more established routine of screening mammography has been questioned by the results of the Canadian National Breast Screening Study. Many authors challenge this study's validity. Largely because of screening mammography, noninvasive breast cancer is one of the most frequently diagnosed types of breast cancer. The treatment options for noninvasive breast cancers are discussed along with recent publications. The option of breast-conserving therapy for early stage cancers is also reviewed. Recent investigators have sought to identify the most appropriate patients for breast conservation. This overview also discusses treatment options for advanced cancers and the use of hormonal therapy for all patients with breast cancer.
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Brigham and Women's Hospital, Surgical Oncology Division, Boston, MA 02115, USA.
D001943:Breast Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008327:Mammography; D008403:Mass Screening; D015412:Mastectomy, Segmental; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D016879:Salvage Therapy; D015996:Survival Rate