title: [Urokinase in a premature infant: its use in a case of right atrial thrombosis secondary to catheterization of the umbilical vein].
abstract: Newborns with vascular catheters must be investigated by echocardiogram for intracardiac thrombosis. We report the use of urokinase to treat an asymptomatic right atrial thrombus in a 31 weeks' gestation newborn; the thrombosis occurred after placement of a catheter in the umbilical vein. We obtained a safe and successful thrombolysis using urokinase 4000 U/kg/h in continuous infusion.
authors.affiliation: Divisione di Patologia Neonatale e Terapia Intensiva, Ospedale Civile di Rho, MI, Italia.
authors.forename: C
authors.initials: C
authors.lastname: Colnaghi
authors.forename: M A
authors.initials: MA
authors.lastname: Cazzuffi
authors.forename: P
authors.initials: P
authors.lastname: Introvini
authors.forename: R
authors.initials: R
authors.lastname: Fornerone
authors.forename: I
authors.initials: I
authors.lastname: Sabatini
authors.forename: F
authors.initials: F
authors.lastname: Borin
authors.forename: L A
authors.initials: LA
authors.lastname: Magni
mesh_terms: D002406:Catheterization, Peripheral / Q000009:adverse effects*; D004452:Echocardiography; D005865:Gestational Age; D006325:Heart Atria / Q000000981:diagnostic imaging; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D014471:Umbilical Veins; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Urochinasi nel prematuro: utilizzo in un caso di trombosi atrial destra secondaria a cateterizzazione della vena ombelicale.