Screening of selected medicinal plants of Nepal for antimicrobial activities.
In an ethnopharmacological screening of selected medicinal plants used in Nepal, methanol extracts from 21 plant species were assayed for activity against 8 strains of bacteria and 5 strains of fungi. Duplicate assays were conducted with and without exposure to UV-A radiation to test for light-activated or light-enhanced activity. All 21 of the extracts showed activity against at least 2 bacterial strains, and 20 showed activity against at least 2 fungi. Six extracts were active only when exposed to UV-A light, and the antibiotic or antifungal effect of 14 extracts was enhanced upon exposure to light.
Taylor
R S
RS
Department of Botany, University of British Columbia, Vancouver, Canada.
Manandhar
N P
NP
Towers
G H
GH
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D008519:Medicine, Traditional; D000432:Methanol; D008826:Microbial Sensitivity Tests; D009390:Nepal; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000145:classification
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts; D000432:Methanol