title: [ACE inhibitors and early diabetic nephropathy].
abstract: At present we are able to disclose diabetic nephropathy in the very early stages, i.e. when urinary albumin excretion is only slightly increased (20-200 micrograms/min = microalbuminuria). Good blood glucose control and active antihypertensive treatment may stop or retard the further development towards renal failure. Angiotensin-converting-enzyme (ACE)-inhibitors seem to have a renoprotective effect. In this article we suggest guidelines for the use of ACE-inhibitors in patients with type 1 diabetes and early diabetic nephropathy. Special concerns are included in respect of adolescents, pregnant women and persons with type 2 diabetes.
authors.affiliation: Barneavdelingen/Aker diabetes forskningssenter, Aker sykehus, Oslo.
authors.forename: H J
authors.initials: HJ
authors.lastname: Bangstad
authors.forename: A
authors.initials: A
authors.lastname: Hartmann
authors.forename: T J
authors.initials: TJ
authors.lastname: Berg
authors.forename: K F
authors.initials: KF
authors.lastname: Hanssen
mesh_terms: D000419:Albuminuria / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage*; D001786:Blood Glucose / Q000032:analysis; D003928:Diabetic Nephropathies / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D001786:Blood Glucose
vernacular_title: ACE-hemmere og tidlig diabetisk nefropati.