title: Goiter prevalence in children immigrating from an endemic goiter area in Ethiopia to Israel.
abstract: A survey study was performed to assess the prevalence of goiter and thyroid dysfunction in a population of 534 Ethiopian children, one year after arrival in Israel. The overall prevalence of goiter was 43.6%. Children in the age group 1-2 years had the lowest prevalence of goiter (6.7%). A progressive increase in goiter prevalence and size with age was observed, with peak occurrence around puberty for both boys (56.7%) and girls (72.2%). Serum FT4 levels were elevated in 4 children; elevated serum TSH levels (above 4.5 mIU/l) were found in 11 children, all of them had normal FT4 levels. Thus the prevalence of hypothyroidism and hyperthyroidism was 2% and 0.8%, respectively, with an even distribution across the various age groups. All the children were clinically normal. The high prevalence of goiter in this group of Ethiopian children with the low frequency of hypothyroidism may be attributed to the combined effects of food goitrogens and iodine deficiency prevailing in Ethiopia. The standard Israeli diet seems to be adequate in respect to iodine requirements, and no iodine enrichment is needed for children immigrating from Ethiopia.
authors.affiliation: Department of Endocrinology, Central Emek Hospital, Afula, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Luboshitzky
authors.forename: Y
authors.initials: Y
authors.lastname: Dgani
authors.forename: S
authors.initials: S
authors.lastname: Atar
authors.forename: G
authors.initials: G
authors.lastname: Qupty
authors.forename: A
authors.initials: A
authors.lastname: Tamir
authors.forename: E
authors.initials: E
authors.lastname: Flatau
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004032:Diet; D004641:Emigration and Immigration; D005002:Ethiopia / Q000453:epidemiology / Q000208:ethnology; D005260:Female; D006042:Goiter / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology; D007037:Hypothyroidism / Q000209:etiology; D007223:Infant; D007455:Iodine / Q000008:administration & dosage / Q000172:deficiency; D007557:Israel; D008297:Male; D011627:Puberty; D013959:Thyroid Diseases / Q000453:epidemiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D013972:Thyrotropin; D007455:Iodine; D013974:Thyroxine