title: Effect of root canal filling materials containing calcium hydroxide on the alkalinity of root dentin.
abstract: The effect of root canal filling pastes containing calcium oxide resp. calcium hydroxide on the alkalinity of extracted human teeth was investigated using a colour indicator (cresol red). An aqueous suspension of calcium hydroxide (Pulpdent), which is normally used for temporary root canal filling, most consistently produced alkalinity. Removal of the smear layer following instrumentation of the root canal led to increased proportion of alkaline-positive spots in dentinal locations distant from the canal. A clearly smaller effect was found with a calcium salicylate cement (Sealapex) and an oil-paste (Gangraena Merz), both of which are available for definite root canal fillings. Following removal of the smear layer, these hard-setting preparations caused moderate alkalinity in dentin adjacent to the canal but no effect was observed in locations more distant from the canal. Neither at locations adjacent to nor distant from the root canal was alkalinity found when another calcium salicylate cement (Apexit) was used. Apparently the release of hydroxyl ions into root dentin from calcium hydroxide containing root canal filling materials is not solely influenced by the absolute amount of calcium hydroxide, but also depends on other ingredients which variably inhibit the release of these ions.
authors.affiliation: Poliklinik fur Zahnerhaltungskunde der Universität Heidelberg, Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Staehle
authors.forename: V
authors.initials: V
authors.lastname: Spiess
authors.forename: A
authors.initials: A
authors.lastname: Heinecke
authors.forename: H P
authors.initials: HP
authors.lastname: Müller
mesh_terms: D016010:Binomial Distribution; D002126:Calcium Hydroxide / Q000737:chemistry / Q000494:pharmacology*; D003738:Dental Cements / Q000737:chemistry / Q000494:pharmacology; D003804:Dentin / Q000737:chemistry / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D016013:Likelihood Functions; D012387:Root Canal Filling Materials / Q000737:chemistry / Q000494:pharmacology*; D012459:Salicylates / Q000737:chemistry / Q000494:pharmacology; D016369:Smear Layer; D014092:Tooth Root / Q000737:chemistry / Q000187:drug effects*
chemical_list: C074418:Apexit; D003738:Dental Cements; D012387:Root Canal Filling Materials; D012459:Salicylates; C055601:Sealapex; C096476:Gangraena Merz; C029777:Pulpdent; D002126:Calcium Hydroxide