Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.
Crystal
R G
RG
Rockefeller University Hospital, New York, New York 10021, USA.
Mastrangeli
A
A
Sanders
A
A
Cooke
J
J
King
T
T
Gilbert
F
F
Henschke
C
C
Pascal
W
W
Herena
J
J
Harvey
B G
BG
D000256:Adenoviridae / Q000235:genetics* / Q000502:physiology; D000293:Adolescent; D000328:Adult; D002985:Clinical Protocols; D002986:Clinical Trials as Topic; D003550:Cystic Fibrosis / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D018076:DNA, Complementary / Q000008:administration & dosage / Q000235:genetics; D005260:Female; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000009:adverse effects; D006801:Humans; D008297:Male; D011994:Recombinant Proteins / Q000235:genetics; D014779:Virus Replication
C505032:CFTR protein, human; D018076:DNA, Complementary; D011994:Recombinant Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator