title: Genotoxicity testing of two red dyes in the somatic and germ line cells of Drosophila.
abstract: Two red dyes, rhodamine B and amaranth, were tested for their genotoxic effects in the somatic (wing primordia) and germ line cells of Drosophila melanogaster following the wing spot and the sex-linked recessive lethal tests. Second- and third-instar larvae, carrying suitable genetic markers, were subjected to chronic exposure to different concentrations of the test dyes. The results indicate that rhodamine is genotoxic in both somatic and germ line cells and amaranth is non-genotoxic.
authors.affiliation: Department of Zoology, Berhampur University, Orissa, India.
authors.forename: N K
authors.initials: NK
authors.lastname: Tripathy
authors.forename: M J
authors.initials: MJ
authors.lastname: Nabi
authors.forename: G P
authors.initials: GP
authors.lastname: Sahu
authors.forename: A A
authors.initials: AA
authors.lastname: Kumar
mesh_terms: D000014:Abnormalities, Drug-Induced; D000548:Amaranth Dye / Q000633:toxicity*; D000818:Animals; D004396:Coloring Agents / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004331:Drosophila melanogaster; D005819:Genetic Markers / Q000187:drug effects; D005854:Germ Cells / Q000187:drug effects*; D008297:Male; D012235:Rhodamines / Q000633:toxicity*; D014921:Wings, Animal / Q000002:abnormalities*; D014960:X Chromosome / Q000187:drug effects
chemical_list: D004396:Coloring Agents; D005819:Genetic Markers; D012235:Rhodamines; D000548:Amaranth Dye; C029773:rhodamine B