title: Graphical models for panel studies, illustrated on data from the Framingham Heart Study.
abstract: Recursive graphical models allow description of the simultaneous development of several (discrete) characteristics such as are recorded in a panel study. Irreversible events (death, irreversible disease occurrence) between exams are naturally included. This paper reviews these models and gives a detailed discussion of an example consisting of 49-50 year old males from the Framingham Heart study. The program DIGRAM is used throughout and the present paper may also serve as an introduction to this software.
authors.affiliation: Division of Biostatistics, Medical College of Wisconsin, Milwaukee 53226, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Klein
authors.forename: N
authors.initials: N
authors.lastname: Keiding
authors.forename: S
authors.initials: S
authors.lastname: Kreiner
mesh_terms: D002423:Cause of Death; D002561:Cerebrovascular Disorders / Q000401:mortality; D015331:Cohort Studies; D003196:Computer Graphics; D003327:Coronary Disease / Q000401:mortality*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008432:Mathematical Computing; D008875:Middle Aged; D015233:Models, Statistical; D012307:Risk Factors