title: Acute renal failure in high dose carboplatin chemotherapy.
abstract: Carboplatin has been reported to cause acute renal failure when administered in high doses to adult patients. We report a 4 1/2-year-old girl who was treated with high-dose carboplatin for metastatic parameningeal embryonal rhabdomyosarcoma. Acute renal failure developed followed by a slow partial recovery of renal function. Possible contributing factors are discussed.
authors.affiliation: Department of Paediatrics, Emma Kinderziekenhuis/Academic Medical Centre, University of Amsterdam, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Frenkel
authors.forename: G
authors.initials: G
authors.lastname: Kool
authors.forename: J
authors.initials: J
authors.lastname: de Kraker
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D016190:Carboplatin / Q000009:adverse effects*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000556:secondary; D018233:Rhabdomyosarcoma, Embryonal / Q000188:drug therapy / Q000556:secondary
chemical_list: D016190:Carboplatin