Current status of genetic research in Rett syndrome.
Rett syndrome is a progressive neurological development syndrome. Evidences for a genetic transmission, but no conclusive data which entirely support the X chromosome involvement, exist. The chromosomal region 11p14-pte has been investigated with polymorphic markers and genes in the region have been sequenced. No sequence divergencies were detected.
Anvret
M
M
Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
Zhang
Z P
ZP
D002880:Chromosomes, Human, Pair 11; D006801:Humans; D015518:Rett Syndrome / Q000235:genetics*; D012737:Sex Factors; D014960:X Chromosome