title: Mouse model systems to study multistep tumorigenesis.
authors.affiliation: Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam.
authors.forename: A
authors.initials: A
authors.lastname: Berns
authors.forename: N
authors.initials: N
authors.lastname: van der Lugt
authors.forename: M
authors.initials: M
authors.lastname: Alkema
authors.forename: M
authors.initials: M
authors.lastname: van Lohuizen
authors.forename: J
authors.initials: J
authors.lastname: Domen
authors.forename: D
authors.initials: D
authors.lastname: Acton
authors.forename: J
authors.initials: J
authors.lastname: Allen
authors.forename: P W
authors.initials: PW
authors.lastname: Laird
authors.forename: J
authors.initials: J
authors.lastname: Jonkers
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000002:abnormalities; D003043:Cocarcinogenesis; D004195:Disease Models, Animal; D005801:Genes, Homeobox; D016259:Genes, myc; D006410:Hematopoiesis / Q000235:genetics; D008223:Lymphoma / Q000209:etiology / Q000235:genetics; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D008822:Mice, Transgenic; D009154:Mutation; D009374:Neoplasms, Experimental / Q000209:etiology* / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics; D009857:Oncogenes; D063150:Polycomb Repressive Complex 1; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins / Q000235:genetics; D051573:Proto-Oncogene Proteins c-pim-1; D011533:Proviruses / Q000235:genetics; D012097:Repressor Proteins
chemical_list: C489421:Bmi1 protein, mouse; D009687:Nuclear Proteins; C490587:PIM2 protein, human; C094167:Pim2 protein, mouse; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D063150:Polycomb Repressive Complex 1; C496636:Pim1 protein, mouse; D017346:Protein Serine-Threonine Kinases; D051573:Proto-Oncogene Proteins c-pim-1