title: Radiation-induced primary brain lymphoma: a case report.
abstract: A patient who developed primary brain lymphoma 6 years following whole brain irradiation due to a low-grade glioma is described. The patient had no evidence of congenital or acquired immunodeficiency state and achieved a good and prompt response to aggressive chemotherapy, including high-dose methotrexate. The previous radiation therapy is implicated in the etiology of the lymphoma because of the geometric coincidence, the relatively long latency period and the different histology. A brief review of current literature is reported.
authors.affiliation: Chemotherapy Unit, Northern Israel Oncology Center, Haifa, Israel.
authors.forename: M E
authors.initials: ME
authors.lastname: Stein
authors.forename: N
authors.initials: N
authors.lastname: Haim
authors.forename: M
authors.initials: M
authors.lastname: Ben-Shachar
authors.forename: D
authors.initials: D
authors.lastname: Goldsher
authors.forename: Z
authors.initials: Z
authors.lastname: Bernstein
authors.forename: Y
authors.initials: Y
authors.lastname: Ben-Arieh
authors.forename: A
authors.initials: A
authors.lastname: Kuten
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology / Q000532:radiotherapy*; D005910:Glioma / Q000532:radiotherapy*; D006801:Humans; D008223:Lymphoma / Q000209:etiology* / Q000473:pathology; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects