[The characteristics of the corticosteroid receptors in the hormonal modification of the stress reactivity of rats].
After neonatal administration of hydrocortisone the rat litter preserve inhibition of function of the hypophyseal-adrenal system at the age under 2 months. During the inhibition period, the number of corticosteroid receptors was decreased in the hypothalamus and hippocampus and increased in the hypophysis. At the 3-month age, binding of corticosteroids in these structures is restored.
Shaliapina
V G
VG
Efimov
S V
SV
Pivina
S G
SG
Ordian
N E
NE
Rakitskaia
V V
VV
D000311:Adrenal Glands / Q000737:chemistry; D000375:Aging / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D001923:Brain Chemistry / Q000187:drug effects; D003345:Corticosterone / Q000032:analysis / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology*; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000502:physiology; D011869:Radioligand Assay; D051381:Rats; D017208:Rats, Wistar; D011987:Receptors, Steroid / Q000187:drug effects* / Q000378:metabolism; D013312:Stress, Physiological / Q000378:metabolism / Q000503:physiopathology*
D011987:Receptors, Steroid; D003345:Corticosterone; D006854:Hydrocortisone
Kharakteristika kortikosteroidnykh retseptorov pri gormonal'noĭ modifikatsii stress-reaktivnosti u krys.