title: Histopathological evaluation of the carbon fibers application for the substitution of the anterior cruciate ligament--an experimental study on dogs.
abstract: The application of allograft-carbon fibers on the experimental group of 15 dogs (German Shepherd race) was histopathologically investigated after the artificial lesion of anterior cruciate ligament (ACL). In definite time intervals (1, 2, 4, 6 months) pathoanatomic and histopathologic findings were analyzed and the proliferation of new connective tissue of predominantly elastic type, between carbon fibers was observed. Beside the lymphocyte infiltration around torn carbon fibers giant cells of a foreign body type were found, and on the surface the epithelium similar to synovial was observed. It was concluded that carbon fibers could not be considered as the ideal artificial ligament.
authors.affiliation: University Clinical Center, Clinic for Orthopedic Surgery and Traumatology, Belgrade.
authors.forename: A
authors.initials: A
authors.lastname: Lesić
authors.forename: D
authors.initials: D
authors.lastname: Durdević
authors.forename: V
authors.initials: V
authors.lastname: Tatić
authors.forename: D
authors.initials: D
authors.lastname: Ukropina
mesh_terms: D000818:Animals; D016118:Anterior Cruciate Ligament / Q000473:pathology / Q000601:surgery*; D002244:Carbon; D000077482:Carbon Fiber; D004285:Dogs; D019736:Prostheses and Implants
chemical_list: D000077482:Carbon Fiber; D002244:Carbon