Successful treatment with ganciclovir of presumed Epstein-Barr meningo-encephalitis following bone marrow transplant.
Epstein-Barr virus-specific polymerase chain reaction was used to diagnose EBV-meningo-encephalitis in a bone marrow transplant recipient. The patient made complete recovery with ganciclovir treatment. Pitfalls in diagnosis with EBV-PCR and the potential therapeutic efficacy of ganciclovir in EBV infections are discussed.
Dellemijn
P L
PL
Department of Neuro-oncology, Dr. Daniël Den Hoed Cancer Center, Rotterdam, The Netherlands.
Brandenburg
A
A
Niesters
H G
HG
van den Bent
M J
MJ
Rothbarth
P H
PH
Vlasveld
L T
LT
D000998:Antiviral Agents / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use*; D006566:Herpesviridae Infections / Q000188:drug therapy*; D004854:Herpesvirus 4, Human; D006801:Humans; D008590:Meningoencephalitis / Q000188:drug therapy*; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000188:drug therapy*
D000998:Antiviral Agents; D015774:Ganciclovir