title: The incidence of hyperemesis gravidarum is increased among Pacific Islanders living in Wellington.
abstract: OBJECTIVE
  To compare the incidence of hyperemesis gravidarum among Pacific Islanders living in Wellington with nonPacific Islanders and to investigate some properties of the disorder.
  
  
  METHODS
  Data were collected on all first time admissions to Wellington Women's Hospital for hyperemesis gravidarum over a 5-year period. Women were classified as having severe hyperemesis gravidarum if abnormalities of serum electrolytes and liver function tests results were present and as less severe if these abnormalities were absent. Almost all women had ketonuria. Mantel-Haenszel odds ratios, chi 2 analysis and Fisher's 2-tailed exact test were used for statistical analysis.
  
  
  RESULTS
  The proportion of hyperemesis gravidarum patients who were Pacific Islanders was significantly increased when compared to their proportion in a control group (p < 0.01). The difference remained significant when the hyperemesis patients were divided into less and more severe. Abnormal thyroid function test results were more common among Pacific Island patients than among nonPacific Island patients. This difference was significant (p < 0.01) only in the less severe group.
  
  
  CONCLUSIONS
  The incidence of hyperemesis gravidarum is significantly increased among Pacific Island women (especially Samoans) living in Wellington and is often associated with abnormalities of thyroid function test results.
authors.affiliation: Department of Pathology, Wellington School of Medicine.
authors.forename: V
authors.initials: V
authors.lastname: Jordan
authors.forename: J
authors.initials: J
authors.lastname: MacDonald
authors.forename: S
authors.initials: S
authors.lastname: Crichton
authors.forename: P
authors.initials: P
authors.lastname: Stone
authors.forename: H
authors.initials: H
authors.lastname: Ford
mesh_terms: D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000208:ethnology* / Q000503:physiopathology; D015994:Incidence; D009520:New Zealand / Q000453:epidemiology; D010139:Pacific Islands / Q000208:ethnology; D011247:Pregnancy; D012189:Retrospective Studies; D013960:Thyroid Function Tests