title: [Preliminary analysis of relationship between immunological changes and syndrome differentiation-typing in traditional Chinese medicine and prognosis with chronic idiopathic thrombocytopenic purpura].
abstract: In order to study the relationship between the basement immunological changes, TCM Syndrome Differentiation and prognosis, alkaline phosphates antialkaline phosphatase (APAAP) and ELISA assay were used to determine the T lymphocyte subsets, the platelet associated antibody (PAIgG, PAIgA, PAIgM) and plasma antiplatelet-autoantibodies (GP II b, GP III a, GP I b) in 55 chronic idiopathic thrombocytopenic purpura (ITP) and 53 healthy subjects as control. The results indicated that the immunological changes was closely related to the prognosis, while the TCM Syndrome Differentiation was also related to it, which denoted that it is significant to investigate both factors in guiding treatment and assessing the prognosis.
authors.affiliation: Dept. of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing.
authors.forename: Y F
authors.initials: YF
authors.lastname: Yang
authors.forename: A X
authors.initials: AX
authors.lastname: Zhou
authors.forename: R
authors.initials: R
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001792:Blood Platelets / Q000276:immunology; D016516:CD4-CD8 Ratio; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D010980:Platelet Membrane Glycoproteins / Q000276:immunology; D011379:Prognosis; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D007136:Immunoglobulins; D010980:Platelet Membrane Glycoproteins