title: Localization of an ectopic parathyroid adenoma by double-phase technetium-99m-sestamibi scintigraphy.
abstract: Double-phase planar scintigraphy using 99mTc-MIBI has been introduced as a means to detect and localize parathyroid adenomas. Focal uptake on both early and delayed imaging is typical of these entities. We report a patient with persistent hypercalcemia following subtotal parathyroidectomy, who was found scintigraphically to have an ectopic parathyroid adenoma. Following initial detection within the mediastinum using planar scintigraphy, the adenoma was more precisely localized using SPECT imaging. This case suggests that double-phase parathyroid planar scintigraphy augmented with SPECT imaging, if needed, is cost-effective, and often necessary, in the assessment of primary hyperparathyroid patients before surgical reexploration.
authors.affiliation: Nuclear Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
authors.forename: J
authors.initials: J
authors.lastname: Caravalho
authors.forename: A G
authors.initials: AG
authors.lastname: Balingit
authors.forename: J E
authors.initials: JE
authors.lastname: Rivera-Rodríguez
authors.forename: C D
authors.initials: CD
authors.lastname: Shriver
authors.forename: M K
authors.initials: MK
authors.lastname: Koops
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000328:Adult; D002828:Choristoma / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000209:etiology / Q000601:surgery; D008479:Mediastinal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D010280:Parathyroid Glands / Q000000981:diagnostic imaging; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D017256:Technetium Tc 99m Sestamibi