The thermodynamics of DNA structures that contain lesions or guanine tetrads.
It is becoming increasingly apparent that energetic as well as structural information is required to develop a complete appreciation of the critical interrelationships between structure, energetics, and biological function. Motivated by this recognition, we have reviewed in this article the current state of the thermodynamic databases associated with lesion-containing DNA duplexes and DNA quadruplexes, while highlighting important considerations concerning the methods used to obtain the requisite data.
Pilch
D S
DS
Department of Chemistry, Rutgers State University of New Jersey, Piscataway 08855-0939, USA.
Plum
G E
GE
Breslauer
K J
KJ
D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D004249:DNA Damage; D006147:Guanine; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D013816:Thermodynamics
D006147:Guanine; D004247:DNA