title: [Effect of the ketogenic diet for West syndrome into which early infantile epileptic encephalopathy with suppression-burst was evolved].
abstract: A male infant with early infantile epileptic encephalopathy (EIEE) was reported. Tonic spasms in series appeared since 1 month after birth and EEG showed a typical suppression-burst pattern. The patient was treated with a high-dose pyridoxal phosphate and thyrotropin-releasing hormone (TRH), but seizures were not controlled. ACTH was administered and the seizures disappeared transiently. The seizures reappeared during tapering ACTH and apparent cerebral shrinkage followed the ACTH therapy. Then, the patient who evolved into West syndrome was treated with ketogenic diet. The seizures disappeared immediately and EEG findings were improved. It is suggested that the ketogenic diet should be tried early for the treatment of EIEE.
authors.affiliation: Department of Pediatrics, Shimane Medical University, Izumo.
authors.forename: Y
authors.initials: Y
authors.lastname: Takusa
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: A
authors.initials: A
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Sejima
authors.forename: K
authors.initials: K
authors.lastname: Kishi
authors.forename: H
authors.initials: H
authors.lastname: Shiraishi
mesh_terms: D004569:Electroencephalography; D004827:Epilepsy / Q000178:diet therapy* / Q000503:physiopathology; D005526:Food, Formulated; D006801:Humans; D007223:Infant; D007659:Ketones / Q000008:administration & dosage*; D008297:Male; D013036:Spasms, Infantile / Q000178:diet therapy* / Q000503:physiopathology
chemical_list: D007659:Ketones