Effect of sodium hypochlorite exposure on infectivity of Cryptosporidium parvum oocysts for neonatal BALB/c mice.
Oocysts of Cryptosporidium parvum suspended in 5.25, 2.63, or 1.31% aqueous sodium hypochlorite (Clorox laundry bleach) for 10, 30, 60, or 120 min at 21 degrees C were administered by gastric intubation to neonatal BALB/c mice. Microscopic examination of intestinal tissue sections revealed developmental stages of C. parvum in all of the mice.
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Parasite Immunobiology Laboratory, U.S. Department of Agriculture, Beltsville, Maryland 20705, USA.
D000818:Animals; D000831:Animals, Newborn; D003457:Cryptosporidiosis / Q000209:etiology / Q000469:parasitology / Q000517:prevention & control; D016785:Cryptosporidium parvum / Q000187:drug effects* / Q000254:growth & development / Q000472:pathogenicity; D005260:Female; D006801:Humans; D007422:Intestines / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C; D012973:Sodium Hypochlorite / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014343:Trypan Blue
D012973:Sodium Hypochlorite; D014343:Trypan Blue