title: Comparison of two predictive models for prognosis in critically ill patients in a Veteran's Affairs Medical Center coronary care unit.
abstract: OBJECTIVE
  The acute physiologic and chronic health evaluation score has been developed to assess prognosis in critically ill patients. Knaus et al initially determined and validated diagnosis-specific coefficients for prediction of outcome in a group of multidisciplinary ICUs. Teskey et al found different coefficients for cardiac diagnoses in a retrospective analysis of coronary care unit (CCU) only patients. This study compares the actual mortality in a Veteran's Affairs Medical Center (VAMC) CCU with the mortality predicted by the two equations.
  
  
  METHODS
  Data were prospectively collected for patients admitted to the medical CCU at a university-affiliated, tertiary care VAMC.
  
  
  METHODS
  Patients (n = 338) admitted to the CCU with the diagnoses of coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), arrhythmia (Arr), and other cardiac-related diagnoses.
  
  
  RESULTS
  The entire CCU population showed no significant differences from either the predictions by Knaus et al and Teskey et al in 1991. However, when specific disease states were analyzed as a whole, significant differences from both prediction models for CAD and MI actual mortality were found. Teskey et al was a better predictor for the Arr and CHF population, while both were equally reliable for other.
  
  
  CONCLUSIONS
  Either prediction model is reliable for a CCU population in general. However, diagnosis-specific coefficients of Teskey et al appear to correlate better with actual mortality for this VAMC. Significant outcome differences compared with those predicted may reflect the patient population specific to a VAMC.
authors.affiliation: Veteran's Affairs Medical Center, Memphis, Tenn, USA.
authors.forename: E S
authors.initials: ES
authors.lastname: Burnette
authors.forename: R G
authors.initials: RG
authors.lastname: Wunderink
mesh_terms: D018806:APACHE; D003325:Coronary Care Units; D003327:Coronary Disease / Q000401:mortality*; D016638:Critical Illness; D005069:Evaluation Studies as Topic; D006787:Hospitals, Veterans; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate