[Recent advances of studies on interstitial nephritis--definition and pathogenesis].
An abbreviated history describing our understanding of the interstitial nephritis was outlined in the present report. Interstitial nephritis has been recognized with increasing frequency. This nephritis is a diverse group of renal disorders in which the predominant morphologic changes occur in the interstitium included tubules. Recent explosive advances in immunological studies and molecular biological techniques have greatly expanded a study on the mechanisms of interstitial fibrosis.
Sakai
O
O
Second Department of Internal Medicine, Jikei University School of Medicine.
D003094:Collagen / Q000378:metabolism; D016207:Cytokines / Q000502:physiology; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D006801:Humans; D007684:Kidney Tubules / Q000166:cytology / Q000503:physiopathology; D009395:Nephritis, Interstitial / Q000175:diagnosis / Q000209:etiology*
D016207:Cytokines; D003094:Collagen