[The influence of opioid receptor blockade on the behavior of selected biochemical and hormonal parameters in patients with renovascular hypertension studied under water immersion conditions].
10 patients with renovascular hypertension (HRV) and 12 healthy persons were examined under water immersion (WI) conditions without and after blockade of opioid receptors with 2 mg of naloxone. Blood pressure, body mass, change of plasma volume, plasma molality, PRA, and serum values of AVP, aldosterone and catecholamines were evaluated. There were no significant changes between the two examined groups before and after WI. It seems that the drop in blood pressure induced by WI is not only the result of diminished activation of RAAS. The role of opioid receptors in controlling blood pressure and other evaluated parameters is likely in both examined groups.
Baczyński
R
R
Katedry i Nefrologii Slaskiej Akademii Medycznej w Katowicach.
Kokot
F
F
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001827:Body Height / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D016022:Case-Control Studies; D002395:Catecholamines / Q000097:blood; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000503:physiopathology*; D007101:Immersion / Q000503:physiopathology*; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D009994:Osmolar Concentration; D010953:Plasma Volume / Q000502:physiology; D012084:Renin-Angiotensin System / Q000502:physiology*; D014667:Vasopressins / Q000097:blood
D002395:Catecholamines; D009292:Narcotic Antagonists; D014667:Vasopressins; D009270:Naloxone; D000450:Aldosterone
Wpływ blokady receptorów opioidowych na zachowanie sie wybranych parametrów biochemicznych i hormonalnych u chorych na nadciśnienie naczyniowo-nerkowe poddanych immersji wodnej.