Fluorouracil: active in ZD1694 (tomudex)-resistant cell lines with markedly elevated thymidylate synthase levels.
Johnston
P G
PG
Behan
K A
KA
Allegra
C J
CJ
Drake
J C
JC
D004351:Drug Resistance; D005472:Fluorouracil / Q000494:pharmacology*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology* / Q000503:physiopathology; D011799:Quinazolines / Q000494:pharmacology*; D013876:Thiophenes / Q000494:pharmacology*; D013940:Thymidylate Synthase / Q000032:analysis / Q000037:antagonists & inhibitors*; D014407:Tumor Cells, Cultured
D011799:Quinazolines; D013876:Thiophenes; D013940:Thymidylate Synthase; C068874:raltitrexed; D005472:Fluorouracil