title: Selection of women at high risk of breast cancer using two lifestyle markers: a case control study.
abstract: OBJECTIVE
  To select a population of women with high risk of invasive breast cancer by using two markers of high risk lifestyle--age at first delivery > = 25 and daily alcohol intake > = 7 g.
  
  
  METHODS
  Case control study based on a structural interview.
  
  
  METHODS
  Two general practices in Copenhagen, Denmark.
  
  
  METHODS
  30 patients with invasive breast cancer and 30 age-matched controls.
  
  
  METHODS
  The combined selection power of the two markers of high risk lifestyle.
  
  
  RESULTS
  The combined selection power of the two markers was significant (P < 0.025, odds ratio 4.3, 95% CI 1.2-15.6).
  
  
  CONCLUSIONS
  Using these markers it may be possible to select about 80% of all cases of invasive breast cancer in a high risk group comprising only 49% of the female population. This could be of importance for mammography screening; rather than unselectively screening all women in a given age bracket, it might be preferable selectively to screen only the high risk group.
authors.forename: G G
authors.initials: GG
authors.lastname: Erichsen
authors.forename: N E
authors.initials: NE
authors.lastname: Søegaard
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking; D001943:Breast Neoplasms / Q000453:epidemiology; D016022:Case-Control Studies; D015984:Causality; D016009:Chi-Square Distribution; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D011247:Pregnancy