Analysis of diethyltoluamide (DEET) following intentional oral ingestion of Muscol.
N,N-Diethyl-m-toluamide (DEET) is an effective component of several insect repellent products. A 19-year-old woman was admitted to the emergency department following ingestion of 15-25 mL 95% diethyltoluamide (Muscol). Serum and urine toxicology screening tests were negative except for detection of DEET. DEET was qualitatively identified and quantitated by gas chromatography-mass spectrometry. Concentrations of DEET based on selected ion monitoring (ion at m/z 119) were 63.0, 17.2, 1.9, and less than 0.2 mg/L in serum specimens collected at 2, 5, 24, and 48 h following ingestion, respectively. Serial monitoring of DEET concentrations and the cardiac abnormalities observed in this case following oral ingestion were not reported previously.
Fraser
A D
AD
Toxicology Laboratory, Victoria General Hospital, Halifax, Nova Scotia, Canada.
MacNeil
A
A
Theriault
M
M
Morzycki
W
W
D000328:Adult; D003671:DEET / Q000097:blood* / Q000506:poisoning / Q000652:urine*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007302:Insect Repellents / Q000097:blood* / Q000506:poisoning / Q000652:urine; D013406:Suicide, Attempted
D007302:Insect Repellents; D003671:DEET