title: Electrosurgical loop excision of the cervical transformation zone: the experience of family physicians.
abstract: BACKGROUND
  Electrosurgical loop excision of the cervical transformation zone (ELECTZ) is an excisional surgical procedure for treatment of premalignant cervical disease and the abnormal transformation zone by wire loop electrodes. The purpose of this study was to describe and assess the clinical experiences and complications of family-physician-performed ELECTZ and ELECTZ conization.
  
  
  METHODS
  Women who were scheduled for the ELECTZ or ELECTZ conization procedures were enrolled in the study between March 1992 and March 1993, inclusive. Subjects were recruited from the practices of six family physician colposcopists located at five sites. The ELECTZ and ELECTZ conization procedures were performed on patients with abnormal Papanicolaou (Pap) smears or abnormal histologic results and abnormal colposcopic findings. Procedural complications were documented. Subjects were serially assessed during the first postoperative year by Pap smears, colposcopy, and, when necessary, by biopsy to determine therapeutic cure.
  
  
  RESULTS
  Of 198 subjects enrolled in the study, 148 women were assessed at least once in follow-up by Pap smear and colposcopy. Only 7.6% of women were defined as treatment failures by subsequent histologic assessment. Women treated by ELECTZ conization were older (32.2 vs 25.1 years, P = .02), were more likely to develop posttreatment cervical stenosis (25.9% vs 3.8%, P = .001), and were more likely to have the postoperative squamocolumnar junction positioned in the endocervical canal (32.4% vs 8.7%, P = .002) than were women treated by ELECTZ: Loop excision specimen margins demonstrated dysplasia for 27 (13.6%) subjects. Significant operative bleeding (> 25 mL) was noted in 6.8% of subjects. Histologic thermal artifact was reported for 9.6% of specimens. One case of microinvasive cancer and one case of invasive cancer were identified unexpectedly by ELECTZ conization.
  
  
  CONCLUSIONS
  Electrosurgical loop excision of the cervical transformation zone and ELECTZ conization may be safely and effectively performed in office settings by family physicians. Complications and treatment failure rates for the ELECTZ and ELECTZ conization procedures were similar to those experienced by other clinicians.
authors.affiliation: Department of Family Medicine, Medical College of Georgia, Augusta 30912, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Ferris
authors.forename: B L
authors.initials: BL
authors.lastname: Hainer
authors.forename: J L
authors.initials: JL
authors.lastname: Pfenninger
authors.forename: T J
authors.initials: TJ
authors.lastname: Zuber
authors.forename: D E
authors.initials: DE
authors.lastname: DeWitt
authors.forename: R L
authors.initials: RL
authors.lastname: Line
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy / Q000592:standards; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery*; D003127:Colposcopy; D019092:Conization / Q000379:methods; D004598:Electrosurgery / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D005194:Family Practice / Q000592:standards; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D065006:Papanicolaou Test; D012907:Smoking; D016896:Treatment Outcome; D014481:United States; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*