Ovarian volume: a novel outcome predictor for assisted reproduction.
OBJECTIVE
To determine the potential of ovarian volume as a predictor of assisted reproduction outcomes.


METHODS
Retrospective chart review.


METHODS
University-based assisted reproduction program.


METHODS
One hundred eighty-eight women initiating their first cycle of assisted reproduction.


METHODS
None.


METHODS
Pretreatment transvaginal ultrasound ovarian measurements were compared with subsequent ovulation induction parameters (peak E2, numbers of oocytes, and embryos) and cycle outcome (cancellation and pregnancy).


RESULTS
Total ovarian volume and volume of the smallest ovary were significant variables predicting peak E2 and numbers of oocytes and embryos. Total ovarian volume was a predictor of cycle cancellation and volume of the smallest ovary a predictor of clinical pregnancy. Large ovarian volumes are associated with good assisted reproductive technology outcomes whereas small ovarian volumes are associated with poor outcomes.


CONCLUSIONS
Beyond maternal age, total ovarian volume, and volume of the smallest ovary are significant predictors of the success of assisted reproductive techniques.
Syrop
C H
CH
Department of Obstetrics and Gynecology, University of Iowa College of Medicine, Iowa City 52242-1080, USA.
Willhoite
A
A
Van Voorhis
B J
BJ
D000328:Adult; D004624:Embryo Transfer; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D009865:Oocytes / Q000166:cytology; D010053:Ovary / Q000000981:diagnostic imaging*; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D012044:Regression Analysis; D012099:Reproductive Techniques; D012189:Retrospective Studies; D014463:Ultrasonography
D004958:Estradiol