[The effect of different classes of radioprotectors on the survival of mice irradiated at a wide range of doses].
In experiments with mice three kinds of dose dependence of radioprotection efficiency were shown for different radioprotectors. Maximum protection was revealed in the ranges of LD70-100/30 for naphthyzin and cystamine, LD50-70/30 for thymogen and lymphokinin, LD70/30 for prodigiosan and polyribonate. The necessity of research of preparations which increase radioresistance in the wide range of doses is pointed. The problem of improved criteria for radioprotector selection is discussed.
Boĭko
V N
VN
Zholus
R B
RB
Legeza
V I
VI
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004353:Drug Evaluation, Preclinical; D005720:Gamma Rays; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000401:mortality; D011837:Radiation-Protective Agents / Q000008:administration & dosage*; D013997:Time Factors
D011837:Radiation-Protective Agents
Issledovanie vliianiia radioprotektorov razlichnykh klassov na vyzhivaemost' mysheĭ, obluchennykh v shirokom diapazone doz.