Capsular types and antimicrobial resistance of Streptococcus pneumoniae isolated in Korea.
The capsular types and the MICs of penicillin G and other antimicrobial agents were determined for 89 isolates of Streptococcus pneumoniae. MICs of penicillin G ranged from 0.015 to 2 mg/l, with 29% and 48% of the isolates exhibiting intermediate resistance and complete resistance, respectively. All isolates were susceptible to teicoplanin and vancomycin, but 81% and 43% of the penicillin G-resistant strains were intermediately resistant to cefotaxime and imipenem, respectively. Strains belonged to 16 different capsular types: 73% belonged to types 19F and 23F, and 97% of strains belonging to these two types exhibited either intermediate or complete resistance to penicillin G.
Chong
Y
Y
Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea.
Lee
K
K
Kwon
O H
OH
Henrichsen
J
J
D000293:Adolescent; D000328:Adult; D016667:Bacterial Capsules; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D006801:Humans; D007723:Korea; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010400:Penicillin G / Q000494:pharmacology*; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification
D010406:Penicillins; D010400:Penicillin G