title: Evolutionary genetics. The silence of the genes.
abstract: A low mutation rate is required for the evolution of large genomes. But is the repression of inadvertent gene expression also important, and is the evolution of complexity limited by the efficiency of noise reduction?
authors.affiliation: Department of Genetics, Cambridge, UK.
authors.forename: L D
authors.initials: LD
authors.lastname: Hurst
mesh_terms: D000818:Animals; D005075:Biological Evolution; D005786:Gene Expression Regulation; D016678:Genome; D006801:Humans; D009154:Mutation