Effect of oat bran supplemented diet on hypercholesterolaemia.
OBJECTIVE
To examine the effect of oat bran supplemented diet on serum cholesterol in hypercholesterolaemic males who had failed to comply with a conventional lipid lowering diet.


METHODS
Run-in period with a conventional lipid lowering diet followed by supplements of oat bran (70 g per day) for six weeks. Wash-out period without oat bran ended the survey.


METHODS
The workplace of Pyhäsalmi Mine, Finland.


METHODS
59 volunteer male miners whose serum cholesterol was over 6.1 mmol/l in spite of a conventional lipid lowering diet.


METHODS
Differences between means for serum cholesterol concentrations at different phases of the survey.


RESULTS
During the oat bran supplemented diet serum total cholesterol decreased by 6.2%, from 6.93 to 6.50 mmol/l (p = 0.000) and LDL cholesterol by 9.5%, from 4.64 to 4.20 mmol/l (p = 0.000). During the wash-out phase serum total cholesterol increased by 2.3%, to 6.65 mmol/l (p = 0.084) and LDL cholesterol by 5.0%, to 4.41 mmol/l (p = 0.021). The reduction in cholesterol levels on oat bran supplement correlated positively with the pre-treatment values.


CONCLUSIONS
Oat bran seems to offer an additional dietary means of coping with hypercholesterolaemia.
Winblad
I
I
Department of Public Health Science, University of Oulu, Finland.
Joensuu
T
T
Korpela
H
H
D000328:Adult; D018554:Avena; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D004043:Dietary Fiber / Q000627:therapeutic use*; D005387:Finland; D005527:Food, Fortified; D006801:Humans; D006937:Hypercholesterolemia / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D014280:Triglycerides / Q000097:blood
D004043:Dietary Fiber; D014280:Triglycerides; D002784:Cholesterol