title: [Regressive bilateral retinoblastoma. Clinical and genetic study. Apropos of a case].
abstract: The authors report the observation of a 35-year-old patient, mother of 5 children 4 of whom are carriers of bilateral retinoblastomas. Two of these children presented lesions suggestive of retinoma retinoblastoma association. The patient had peripheral retinal lesions evoking the diagnosis of regressive bilateral retinoblastoma. At present, the term retinoma or retinocytoma seems to be more adequate. The genetic study of this family was done with D esterase and DNA molecular biology.
authors.affiliation: Institut Hedi Rais d'Ophtalmologie de Tunis, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: Marrakchi
authors.forename: H
authors.initials: H
authors.lastname: Bouguila
authors.forename: M
authors.initials: M
authors.lastname: Ghorbal
authors.forename: N
authors.initials: N
authors.lastname: Ben Osman
authors.forename: F
authors.initials: F
authors.lastname: Munier
authors.forename: S
authors.initials: S
authors.lastname: Ayed
mesh_terms: D000328:Adult; D005134:Eye Neoplasms / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D006801:Humans; D010375:Pedigree; D012075:Remission, Spontaneous; D012175:Retinoblastoma / Q000235:genetics / Q000503:physiopathology*
vernacular_title: Rétinoblastome régressif bilatéral. Etude clinique et génétique. A propos d'un cas.