title: A YAC contig map of the human genome.
abstract: A yeast artificial chromosome library containing 33,000 clones with an average insert size of one megabase of human genomic DNA was extensively analysed by several different procedures for detecting overlaps and positional information. We developed an analysis strategy that resulted, after confirmatory tests, in a YAC contig map reliably covering about 75% of the human genome in 225 contigs having an average size of about ten megabases.
authors.affiliation: Fondation Jean Dausset Centre d'Etude du Polymorphisme Humain, Paris, France.
authors.forename: I M
authors.initials: IM
authors.lastname: Chumakov
authors.forename: P
authors.initials: P
authors.lastname: Rigault
authors.forename: I
authors.initials: I
authors.lastname: Le Gall
authors.forename: C
authors.initials: C
authors.lastname: Bellanné-Chantelot
authors.forename: A
authors.initials: A
authors.lastname: Billault
authors.forename: S
authors.initials: S
authors.lastname: Guillou
authors.forename: P
authors.initials: P
authors.lastname: Soularue
authors.forename: G
authors.initials: G
authors.lastname: Guasconi
authors.forename: E
authors.initials: E
authors.lastname: Poullier
authors.forename: I
authors.initials: I
authors.lastname: Gros
mesh_terms: D002874:Chromosome Mapping / Q000379:methods; D018244:Chromosomes, Artificial, Yeast; D016172:DNA Fingerprinting; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D009693:Nucleic Acid Hybridization; D016324:Sequence Tagged Sites
chemical_list: D005819:Genetic Markers