title: [Use of the B19 strain in the prevention of bovine brucellosis in northern Cameroon. Study of effect of the dose on seroconversion rate and duration in female zebu].
abstract: Four herds of zebus from northern Cameroon totalling 136 animals were vaccinated subcutaneously with the following doses of Brucella abortus strain 19: 5 x 10(9) colony-forming units (CFU), 10(9) CFU, 5 x 10(8) CFU and 10(7) CFU. Twenty-eight days after vaccination, the following seroconversion rates were observed respectively: 97.4, 96.2 84.2 and 73.3%. Of the 52 animals which could be tested subsequently including 39 over one year old on the vaccination day, only one showed antibodies 6 months after vaccination. The cost price of the strain 19 vaccine produced at the Boklé National Veterinary Laboratory was estimated to be 65 F CFA at the 10(9) CFU dose and 1,740 F CFA at the 5 x 10(10) CFU dose usually recommended. The use of the Buck 19 strain in the medical prophylaxis of bovine brucellosis in northern Cameroon is discussed.
authors.affiliation: Laboratoire national vétérinaire de Boklé, Garoua, Cameroun.
authors.forename: A
authors.initials: A
authors.lastname: Martrenchar
authors.forename: D
authors.initials: D
authors.lastname: Bouchel
authors.forename: B M
authors.initials: BM
authors.lastname: Njanpop
authors.forename: A
authors.initials: A
authors.lastname: Yaya
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D002004:Brucella Vaccine / Q000008:administration & dosage*; D002003:Brucella abortus / Q000145:classification / Q000276:immunology*; D002007:Brucellosis, Bovine / Q000517:prevention & control*; D002163:Cameroon; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D005260:Female; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D002004:Brucella Vaccine
vernacular_title: Utilisation de la souche B19 dans la prophylaxie médicale de la brucellose bovine au Nord-Cameroun. Etude de l'effet de la dose sur le taux et la durée de séroconversion chez des femelles zébus.