title: Doppler ultrasound spectral shape downstream of significant arterial stenosis in vivo.
abstract: Peak analysis was applied to pulsed Doppler ultrasound spectra from in vivo poststenotic velocity fields of canine common carotid arteries. Turbulent spectra from a region of jet breakup, five diameters (5 D) down from a 68% diameter reducing stenosis, were closely approximated by a single Gaussian peak. Multiple peaks resulting from the analysis of complex spectra from the shear layers between jet and recirculation zones, 1.5 D downstream of a 40% stenosis, correlated well with the known features of the poststenotic velocity field. It is concluded that peak analysis can be used to separate the spectral components of distinct flow regimes from the complex spectra of regions of complicated flow. This may provide a method for the diagnosis of mild degrees of arterial stenosis using pulsed Doppler ultrasound.
authors.affiliation: Department of Physiology, University of Alberta, Edmonton, Canada.
authors.forename: K J
authors.initials: KJ
authors.lastname: Hutchison
mesh_terms: D000054:Acceleration; D000818:Animals; D001783:Blood Flow Velocity; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D004285:Dogs; D004562:Electrocardiography; D005583:Fourier Analysis; D006339:Heart Rate; D018056:Hemorheology; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D012815:Signal Processing, Computer-Assisted; D013599:Systole; D018617:Ultrasonography, Doppler, Pulsed