title: Dual seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan, Côte d'Ivoire.
abstract: OBJECTIVE
  To determine the absolute and proportional prevalence of dual seroreactivity to HIV-1 and HIV-2 in female sex workers in Abidjan, to determine risk determinants for this serologic profile, and to describe the associated clinical and immunological characteristics.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Confidential clinic for female sex workers in Abidjan.
  
  
  METHODS
  Female sex workers.
  
  
  METHODS
  HIV serostatus, CD4+ counts, women with AIDS, behavioural and sociodemographic characteristics.
  
  
  RESULTS
  Among 1209 women tested, the overall HIV seroprevalence was 80%, while the prevalence of dual seroreactivity was 30%. Dual seroreactivity accounted for 38% of all HIV infections. Compared with women reacting to HIV-1 only, dually seroreactive women were significantly more likely to have been in sex work for a longer period, to be aged > or = 20 years, and to charge less money for intercourse. No difference in mean CD4+ count was noted between women with dual seroreactivity (561 x 10(6)/l) and HIV-1-seropositive women (558 x 10(6)/l).
  
  
  CONCLUSIONS
  Female sex workers in Abidjan had the highest absolute (30%) and proportional rate (38%) of dual seroreactivity yet described in any population. Increased sexual exposure is associated with an increased risk of dual seroreactivity. Although better molecular diagnostic techniques are required, a substantial proportion of female sex workers in Abidjan is likely to be infected with both HIV-1 and HIV-2.
authors.affiliation: Projet RETRO-CI, Abidjan, Côte d'Ivoire.
authors.forename: P D
authors.initials: PD
authors.lastname: Ghys
authors.forename: M O
authors.initials: MO
authors.lastname: Diallo
authors.forename: V
authors.initials: V
authors.lastname: Ettiègne-Traoré
authors.forename: K M
authors.initials: KM
authors.lastname: Yeboué
authors.forename: E
authors.initials: E
authors.lastname: Gnaoré
authors.forename: F
authors.initials: F
authors.lastname: Lorougnon
authors.forename: M J
authors.initials: MJ
authors.lastname: Teurquetil
authors.forename: M L
authors.initials: ML
authors.lastname: Adom
authors.forename: A E
authors.initials: AE
authors.lastname: Greenberg
authors.forename: M
authors.initials: M
authors.lastname: Laga
mesh_terms: D000328:Adult; D007560:Cote d'Ivoire / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D015528:HIV Seroprevalence; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D012307:Risk Factors; D011477:Sex Work