Activities of acetylcholinesterase and NA+, K+ -ATP-ase in human erythrocytes after ethanol consumption.
The influence of ethanol consumption on acetylcholinesterase (AchE) and Na+, K+ -ATP-ase activities was examined in 14 healthy volunteers after 30 minutes of ethanol treatment at a dose 0.6 g/kg of body weight. It was observed that the activity of both enzymes decreased. The activity of AchE was significantly lower, and that of Na+, K+ -ATP-ase tended to be lower, but the difference was not significant. In vitro experiments showed that ethanol inhibited the AchE and N+, K+ -ATP-ase activities immediately and in proportion to the concentration of ethanol used.
Dudek
I M
IM
Department of Medical Physiology, Military Medical Academy, Lodz, Poland.
Kedziora
J
J
Zagórski
T
T
Chmielewski
H
H
Lisiewicz
J
J
Mazurek
M
M
D000110:Acetylcholinesterase / Q000097:blood*; D000328:Adult; D000428:Alcohol Drinking / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D008297:Male; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
D000110:Acetylcholinesterase; D000254:Sodium-Potassium-Exchanging ATPase