Haemoglobin engineering. For fun and money.
The recent transplantation of an unusual allosteric effect from crocodile to human haemoglobin has implications for both molecular evolution and the engineering of artificial blood substitutes.
Brunori
M
M
Department of Biochemical Sciences A. Rossi Fanelli, University of Rome La Sapienza, Italy.
Cutruzzolà
F
F
Vallone
B
B
D000489:Alligators and Crocodiles; D000494:Allosteric Regulation; D000818:Animals; D005075:Biological Evolution; D001802:Blood Substitutes / Q000737:chemistry; D005818:Genetic Engineering; D006454:Hemoglobins / Q000737:chemistry / Q000235:genetics; D006801:Humans; D015394:Molecular Structure
D001802:Blood Substitutes; D006454:Hemoglobins