Inhibition of mammary carcinogenesis in rats by sulfone metabolite of sulindac.
Thompson
H J
HJ
AMC Cancer Research Center, Denver, CO 80214, USA.
Briggs
S
S
Paranka
N S
NS
Piazza
G A
GA
Brendel
K
K
Gross
P H
PH
Sperl
G J
GJ
Pamukcu
R
R
Ahnen
D J
DJ
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000201:enzymology* / Q000517:prevention & control*; D011451:Prostaglandin-Endoperoxide Synthases / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013467:Sulindac / Q000031:analogs & derivatives / Q000378:metabolism / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D013467:Sulindac; C025462:sulindac sulfide; D011451:Prostaglandin-Endoperoxide Synthases; C025463:sulindac sulfone