[Comparative study of the suture of pancreatic stump with absorbable and unabsorbable threads in rats].
The safety of suture and healing of pancreas after surgery with absorbable and unabsorbable suture was studied. One hundred and twenty female rats was underwent a segmentar pancreatic resection. The pancreatic suture was performed with catgut in Group I (n = 48), polygalactin in Group II (n = 48) and silk in Group III (n = 24). The animals were sacrificed at 5th, 10th, 20th and 30th days after surgery and analized at macroscopy: inflammatory signs, fistula, abscess and suture bearing in tissue. Microscopic findings were: suture bearing in tissue, inflammatory aspects against suture, necrosis, edema, neovascular modifications, fibrosis and the collagen's type. After comparing the results with Wilcoxon's two sample test, we concluded that pancreatic healing was not modified with differents sutures, and then pancreatic absorbable or unabsorbable suture was safe.
Costa
I P
IP
Departamento de Cirurgia, Faculdade de Medicina, Universidade Federal de Minas Gerais-FM-UFMG.
Lázaro da Silva
A
A
Gobbi
H
H
D000818:Animals; D005260:Female; D005355:Fibrosis; D005549:Foreign-Body Reaction; D009336:Necrosis; D010179:Pancreas / Q000473:pathology / Q000601:surgery*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013537:Sutures; D014945:Wound Healing
Estudo comparativo da sutura do coto pancreático com fios absorvível e inabsorvível em ratos.