[Complications in the intraperitoneal chemotherapy with the implantable intraperitoneal port and the strategy for the prevention of the complication].
Fifty-four patients with gastrointestinal carcinomas were treated with intraperitoneal chemotherapy through devices, and an implantable port system which had been used subcutaneously. The complications of the implantable ports were analysed in this study. There were 1 bowel perforation, 2 cases of retention of ascites, 2 infections, 2 inflow obstructions and 8 cases of pain, especially in the perineal or lower abdominal area. The number of patients requiring removal of the device due to complications were 7; 1 perforation, 2 ascites, 2 infections and 2 for pain. The strategy for reducing the complications due to the device were analysed as follows. A soft catheter should be selected. The catheter in the abdominal cavity should not be long, not as long as the tip of catheter touch the bottom of pelvic organs. Due care for kinking of the catheter should be taken in the implanting procedure. Antibiotics should be applied in and around the port. Steroids should be added to the solution for intraperitoneal chemotherapy.
Maruyama
M
M
Division of Surgery, Tokyo Metropolitan Ohokubo Hospital.
Takamatsu
H
H
Sugano
N
N
Katada
M
M
Ebuchi
M
M
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001202:Ascitic Fluid / Q000209:etiology / Q000517:prevention & control*; D002945:Cisplatin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D005770:Gastrointestinal Neoplasms / Q000628:therapy; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects*; D007263:Infusions, Parenteral; D007416:Intestinal Perforation / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D002945:Cisplatin; D005472:Fluorouracil; D008727:Methotrexate