title: Antibiotic pasting for foul putrefactive cancers.
abstract: Putrefaction of cancers in infrequent. Nonetheless, it presents a difficult clinical problem of foulness. We prepared 5% antibiotic pastes by adding sodium polyacrylate to aliquots of antibiotic solutions, and applied them to putrefactive lesions in 4 cases of rectal cancer, 2 of breast cancer and 1 of tongue cancer. The putrefaction was promptly brought under control in all of them, permitting an improved QOL. Concomitant application of anticancer pastes was also found remarkably effective. Use of sulperazone may offer a better chance of overcoming the beta lactamase barrier in cases of prolonged use.
authors.affiliation: Department of Radiology, Tohoku Rosai Hospital, Sendai.
authors.forename: S
authors.initials: S
authors.lastname: Okuyama
mesh_terms: D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D002438:Cefoperazone / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007239:Infections / Q000188:drug therapy; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013407:Sulbactam / Q000627:therapeutic use; D014062:Tongue Neoplasms / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D004338:Drug Combinations; D002438:Cefoperazone; C057923:sulperazone; D013407:Sulbactam