[Pulmonary and cardiopulmonary transplantation in mucoviscidosis].
As early as 1987, several teams in France began lung transplantation for patients with cystic fibrosis. Most of these teams propose transplantation when the life expectancy is under 2 years. The major functional criteria are VEMS < 30%, PaC02 > 50 mmHg and PaO2 < 55 mmHg. This contribution focuses on psychologic, nutritional and infectious aspects required in preparing the patients for transplantation and on graft selection. Surgical techniques and patient care after transplantation are also reported. The overall probability of survival after transplantation for cystic fibrosis is 48, 35 and 29% at 1, 2 and 3 years respectively with wide intercentre variation. The lack of sufficient graft supply and the risk of post-transplantation degradation remain the two principal problems for transplantation in cystic fibrosis.
Haloun
A
A
CHU, Nantes.
Horeau
D
D
Treilhaud
M
M
Portier
D
D
Goarin
Y
Y
Videcoq
M
M
al Habash
O
O
Jegou
B
B
de Lajartre
A Y
AY
Baron
O
O
D003550:Cystic Fibrosis / Q000601:surgery*; D005260:Female; D016041:Heart-Lung Transplantation; D006801:Humans; D008017:Life Expectancy; D016040:Lung Transplantation; D008297:Male; D017063:Outcome Assessment, Health Care; D011182:Postoperative Care; D011300:Preoperative Care; D015996:Survival Rate
Transplantation pulmonaire et cardiopulmonaire au cours de la mucoviscidose.