title: [The use of a single anterior oblique field in the treatment of T1aN0 vocal cord neoplasms. Results and comparison with other technics].
abstract: From 1985 through 1993, 113 patients affected with T1N0 glottic cancer were treated with irradiation alone at the Radiotherapy Department of Umberto I Hospital in Mestre, Italy. An anterior oblique beam of 12 MV X-rays (LINAC) or gamma-rays of a Cobalt unit were used. Dose distribution was always studied on CT scans and with a Theraplan V05-B, Theratronics. Patients age ranged 40-92 years (mean: 64.7 years) and they were mostly males. The dose was always 60 Gy/30 fractions referred to the 90% isodose. The dose to the target volume ranged 90-105%, with a mean of 99%. The follow-up ranged 26 to 98 months; the median and the mean are 38 and 40 months, respectively. Six patients had local relapses and were all operated on: cordectomy was performed in 3 of them and laryngectomy in the other 3. Radiation therapy yielded 94.7% disease control; the lesion was ultimately controlled in 100% of patients after surgical salvage. Fifteen patients died, all of them of non-neoplastic disease. The authors compared this technique with those most frequently used, i.e., wedged opposed lateral fields and wedged anterior oblique beams, and observed that it allows minimal volumes to be irradiated with maximal doses and yields results. Wedged beams are not necessary with this technique. The authors consider irradiation the treatment of choice for early glottic cancer and believe that surgery, with the conservative approach if feasible, should be limited to relapses.
authors.affiliation: Divisione di Radioterapia Oncologica, Ospedale Civile Umberto I, Mestre, Venezia.
authors.forename: M
authors.initials: M
authors.lastname: Antonello
authors.forename: R
authors.initials: R
authors.lastname: Polico
authors.forename: F
authors.initials: F
authors.lastname: Bötner
authors.forename: G
authors.initials: G
authors.lastname: Cazzato
authors.forename: M
authors.initials: M
authors.lastname: Busetto
authors.forename: L
authors.initials: L
authors.lastname: Piccolo
authors.forename: S
authors.initials: S
authors.lastname: Schiavon
authors.forename: G
authors.initials: G
authors.lastname: Pizzi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000379:methods; D014827:Vocal Cords
vernacular_title: Impiego di un campo unico obliquo anteriore nel trattamento delle neoplasie delle corde vocali T1aN0. Risultati e confronto con altre tecniche.