title: Pharmacological effects of oral enzyme combinations.
abstract: Combinations of hydrolytic enzymes have been used for therapy of variety of diseases for a long time, their pharmacology, however, is being recognized only in the course of last decades. In the article, the following pharmacological effects of combinations of oral hydrolytic enzymes are reviewed: fibrinolytic, hemorheologic, anti-edematous, anti-inflammatory, activation of macrophages and NK cells, modulation of adhesion molecules, cytokines and immune complexes. Pharmacological effects are classified on four levels: biochemical, physiological, medical, and immunological. A spectrum of indications of enzyme therapy is inferred from the pharmacological effects: inflammations, traumatological events, surgical interventions, autoimmune and immune complex diseases, rheumatological diseases, viral infections and malignant tumors.
authors.affiliation: Enzyme Research Medical Society, Geretsried, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Stauder
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004338:Drug Combinations; D006801:Humans; D006867:Hydrolases / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D004338:Drug Combinations; D006867:Hydrolases