RNA processing. Wilms' tumour--the splicing connection?
Major isoforms of WT1--products of the tumour suppressor gene WT1, implicated in predisposition to Wilms' tumour--may preferentially interact with splicing factors, suggesting a role for WT1 in RNA processing.
Lamond
A I
AI
EMBL, Heidelberg, Germany.
D000818:Animals; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000235:genetics*; D016162:Genes, Wilms Tumor; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics*; D008969:Molecular Sequence Data; D012323:RNA Processing, Post-Transcriptional; D012326:RNA Splicing; D014157:Transcription Factors / Q000235:genetics*; D025721:WT1 Proteins; D009396:Wilms Tumor / Q000235:genetics*
D004268:DNA-Binding Proteins; D014157:Transcription Factors; D025721:WT1 Proteins