title: The quality of life of patients with life-threatening arrhythmias.
abstract: BACKGROUND
  The treatment of life-threatening arrhythmias with amiodarone or an implantable cardioverter/defibrillator prolongs patient survival but with significant comorbidity. Previous studies have shown diminished health status and increased psychologic distress and inferred a diminished quality of life; however, a multidimensional analysis of quality of life, including patient perception, has not been performed.
  
  
  METHODS
  One hundred four consecutive patients were surveyed regarding patient demographics, health status, psychologic distress, and patient-perceived quality of life. The patients were treated with amiodarone (n = 30) with an implantable cardioverter/defibrillator (n = 45) and the remainder were reference patients (n = 29).
  
  
  RESULTS
  This study confirms that patients who survive life-threatening arrhythmias have diminished health status and increased psychologic distress; however, patient-perceived quality of life is preserved. These patients report a better perceived quality of life (as measured by the Quality of Life Index) than the reference group (22.3 +/- 4.0 vs 20.5 +/- 4.4, P < .05) and their scores are similar to those of normal healthy volunteers (mean score, 21.9). The improved quality of life scores were not dependent on treatment modality (22.1 +/- 4.0 vs 22.4 +/- 4.1 for medical vs surgical groups, respectively).
  
  
  CONCLUSIONS
  Patient-perceived quality of life is maintained in patients who survive life-threatening arrhythmias despite their diminished health status and increased psychologic distress. Measured quality of life is independent of treatment modality. Thus, caution must be exercised in assuming a diminished quality of life in patients who have survived a life-threatening cardiac event.
authors.affiliation: Division of Cardiology, University of Nebraska Medical Center, Omaha, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Arteaga
authors.forename: J R
authors.initials: JR
authors.lastname: Windle
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000523:psychology* / Q000628:therapy; D017147:Defibrillators, Implantable; D004554:Electric Countershock / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D013315:Stress, Psychological / Q000209:etiology*; D011795:Surveys and Questionnaires
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone