title: Murine CD38: an immunoregulatory ectoenzyme.
abstract: CD38 is an ectoenzyme that utilizes NAD+ and is expressed by many cells of hematopoietic origin. Antibodies to CD38 potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.
authors.affiliation: DNAX Research Institute, Palo Alto, CA 94304, USA.
authors.forename: F
authors.initials: F
authors.lastname: Lund
authors.forename: N
authors.initials: N
authors.lastname: Solvason
authors.forename: J C
authors.initials: JC
authors.lastname: Grimaldi
authors.forename: R M
authors.initials: RM
authors.lastname: Parkhouse
authors.forename: M
authors.initials: M
authors.lastname: Howard
mesh_terms: D036541:ADP-ribosyl Cyclase; D051997:ADP-ribosyl Cyclase 1; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000276:immunology*; D001402:B-Lymphocytes / Q000201:enzymology / Q000276:immunology*; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins; D051379:Mice; D009699:N-Glycosyl Hydrolases / Q000276:immunology*; D015398:Signal Transduction
chemical_list: D015703:Antigens, CD; D000943:Antigens, Differentiation; D008562:Membrane Glycoproteins; D009699:N-Glycosyl Hydrolases; D036541:ADP-ribosyl Cyclase; C498155:Cd38 protein, mouse; D051997:ADP-ribosyl Cyclase 1