Cloning and sequence of the feline max, and max 9 transcripts.
Max is the recently discovered heterodimeric partner of the human myc oncogene product. In this report we describe the cloning and sequencing of two differentially spliced transcripts of the feline max gene. Previously published data have shown both myc and max to be highly conserved amongst species, and indeed there is a 100% homology between feline max and max, while the murine equivalent myn is 98% homologous at the amino acid level, with the nucleotide sequences showing a similarity of 98% and 95% respectively.
Gallagher
R C
RC
Department of Veterinary Pathology, University of Glasgow Veterinary School.
Neil
J C
JC
Fulton
R
R
D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D050976:Basic-Leucine Zipper Transcription Factors; D002415:Cats / Q000235:genetics*; D003001:Cloning, Molecular; D017931:DNA Primers; D018076:DNA, Complementary; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D018257:Helix-Loop-Helix Motifs; D016350:Leucine Zippers; D008969:Molecular Sequence Data; D010766:Phosphorylation; D016133:Polymerase Chain Reaction; D016271:Proto-Oncogene Proteins c-myc / Q000378:metabolism; D016415:Sequence Alignment; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D050976:Basic-Leucine Zipper Transcription Factors; D017931:DNA Primers; D018076:DNA, Complementary; D004268:DNA-Binding Proteins; C067850:Myc associated factor X; D016271:Proto-Oncogene Proteins c-myc; D014157:Transcription Factors; C068422:Max protein, mouse