title: Histopathological observations of periapical repair in teeth with radiolucent areas submitted to two different methods of root canal treatment.
abstract: Dogs' teeth with induced chronic periapical periodontitis were treated endodontically by two different methods, and the results were compared. A total of 40 root canals from the upper and lower premolars of two dogs were prepared chemomechanically. In method 1, a high-concentration (5.25%) hypochlorite solution was used during the instrumentation of the root canal, and an antibacterial dressing was applied between sessions, followed by filling of the root canal. In method 2, a low-concentration (0.5%) sodium hypochlorite solution was used as an adjunct to mechanical debridement, and the root canal was filled during the same session. The histopathological results showed that method 1 led to better periapical repair than method 2.
authors.affiliation: Department of Endodontics, Araraquara Dental School, UNESP, Brazil.
authors.forename: M R
authors.initials: MR
authors.lastname: Leonardo
authors.forename: W A
authors.initials: WA
authors.lastname: Almeida
authors.forename: L A
authors.initials: LA
authors.lastname: da Silva
authors.forename: L S
authors.initials: LS
authors.lastname: Utrilla
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002126:Calcium Hydroxide / Q000627:therapeutic use; D003739:Dental Cementum / Q000502:physiology; D004285:Dogs; D004492:Edetic Acid / Q000627:therapeutic use; D010485:Periapical Periodontitis / Q000503:physiopathology / Q000628:therapy*; D010486:Periapical Tissue / Q000503:physiopathology*; D012388:Root Canal Irrigants / Q000008:administration & dosage* / Q000627:therapeutic use; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods*; D012973:Sodium Hypochlorite / Q000008:administration & dosage* / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000891:Anti-Infective Agents, Local; D012388:Root Canal Irrigants; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D002126:Calcium Hydroxide