Functions of fibroblast growth factors and their receptors.
Fibroblast growth factors were first characterized twenty years ago as mitogens of cultured fibroblasts. Despite a wealth of data from experiments in vitro, insights have begun to emerge only recently on the normal function of these growth factors in mice and humans, as a result of studies of natural and experimental mutations in the factors and their receptors.
Wilkie
A O
AO
Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
Morriss-Kay
G M
GM
Jones
E Y
EY
Heath
J K
JK
D000595:Amino Acid Sequence; D000818:Animals; D005346:Fibroblast Growth Factors / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D008024:Ligands; D008969:Molecular Sequence Data; D009154:Mutation; D011487:Protein Conformation; D017468:Receptors, Fibroblast Growth Factor / Q000737:chemistry / Q000502:physiology*
D008024:Ligands; D017468:Receptors, Fibroblast Growth Factor; D005346:Fibroblast Growth Factors