title: Development of sporogonic cycle of Plasmodium vivax in experimentally infected Anopheles albimanus mosquitoes.
abstract: The sporogonic cycle of Plasmodium vivax was established and maintained under laboratory conditions in two different strains of Anopheles albimanus mosquitoes using as a parasite source blood from human patients or from Aotus monkeys infected with the VCC-2 P.vivax colombian isolate. Both the Tecojate strain isolate from Guatemala and the Cartagena strain from the colombian Pacific coast were susceptible to infections with P.vivax. A higher percentage of Cartagena mosquitoes was infected per trial, however the Tecojate strain developed higher sporozoite loads. Intravenous inoculation of Aotus monkeys with sporozoites obtained from both anopheline strains resulted in successful blood infections. Animals infected with sporozoites from the Tecojate strain presented a patent period of 21-32 days whereas parasitemia appeared between days 19-53 in monkeys infected with sporozites from Cartagena strain.
authors.affiliation: Fundación Centro de Primates, Cali, Colombia.
authors.forename: M L
authors.initials: ML
authors.lastname: Salas
authors.forename: J F
authors.initials: JF
authors.lastname: Romero
authors.forename: Y
authors.initials: Y
authors.lastname: Solarte
authors.forename: V
authors.initials: V
authors.lastname: Olano
authors.forename: M A
authors.initials: MA
authors.lastname: Herrera
authors.forename: S
authors.initials: S
authors.lastname: Herrera
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D010966:Plasmodium vivax / Q000254:growth & development*