title: [Presence of Helicobacter pylori in the duodenum, antrum, and fundus in control subjects and patients with duodenal ulcer, gastric ulcer, gastritis, or erosive duodenitis. Histological analysis of 357 subjects].
abstract: The prevalence of Helicobacter pylori infection was studied in 152 subjects with a normal upper gastrointestinal endoscopy, 125 with duodenal ulcer, 25 with gastric ulcer, 46 with erosive gastritis and 9 with erosive duodenitis. Two biopsies from duodenum, antrum and fundus were obtained from each subject during endoscopy for histological diagnosis and Helicobacter pylori search. None of the patients with normal endoscopy and 2% of patients with duodenal ulcers had Helicobacter pylori in duodenal biopsies. These last patients had a significantly higher frequency of Helicobacter pylori in the antrum (71%) than the rest of the studied groups. Five percent of subjects with normal endoscopy and 5% of those with duodenal ulcers had Helicobacter pylori in the antrum. An active gastritis was demonstrated in almost all patients with Helicobacter infection. Intestinal metaplasia occurred almost exclusively in the absence of Helicobacter pylori infection.
authors.affiliation: Departamento de Cirugía y Anatomía Patológica, Facultad de Medicina, Universidad de Chile, Hospital Clínico José Joaquín Aguirre, Santiago de Chile.
authors.forename: A
authors.initials: A
authors.lastname: Csendes
authors.forename: G
authors.initials: G
authors.lastname: Smok
authors.forename: P
authors.initials: P
authors.lastname: Burdiles
authors.forename: C
authors.initials: C
authors.lastname: Blanco
authors.forename: J
authors.initials: J
authors.lastname: Rodas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004381:Duodenal Ulcer / Q000382:microbiology* / Q000473:pathology; D004382:Duodenitis / Q000382:microbiology* / Q000473:pathology; D004386:Duodenum / Q000382:microbiology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005748:Gastric Fundus / Q000382:microbiology; D005756:Gastritis / Q000382:microbiology* / Q000473:pathology; D016481:Helicobacter Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D007422:Intestines / Q000382:microbiology / Q000473:pathology; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011706:Pyloric Antrum / Q000382:microbiology; D013276:Stomach Ulcer / Q000382:microbiology* / Q000473:pathology
vernacular_title: Presencia de Helicobacter pylori en el duodeno, antro y fundo de sujetos controles y pacientes con úlcera duodenal, úlcera gástrica, gastritis o duodenitis erosiva. Análisis histológico de 357 sujetos.