title: Surfactant replacement therapy for non-respiratory distress syndrome neonatal respiratory disease--research or clinical application?
abstract: Research studies have highlighted both physiological and pathological evidence to incriminate surfactant abnormality and/or deficiency in many neonatal respiratory diseases. Data from animal models and clinical studies support the concept that surfactant replacement therapy (SRT) may have a role to play in such problems. There is now, therefore, a need to perform further randomized controlled trials to assess the appropriate clinical application of SRT in non-respiratory distress syndrome neonatal respiratory disease.
authors.affiliation: Department of Child Health, King's College School of Medicine and Dentistry, London, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Greenough
mesh_terms: D006548:Hernia, Diaphragmatic / Q000628:therapy; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D008471:Meconium Aspiration Syndrome / Q000628:therapy; D011014:Pneumonia / Q000628:therapy; D011663:Pulmonary Surfactants / Q000502:physiology / Q000627:therapeutic use*; D012131:Respiratory Insufficiency / Q000628:therapy; D012140:Respiratory Tract Diseases / Q000628:therapy*
chemical_list: D011663:Pulmonary Surfactants