title: [Effects of intraperitoneal insufflation on hematogenous seeding of abdominal infections. Preliminary results of an experimental study in rats].
abstract: Most laparoscopic procedures require the creation of a pneumoperitoneum. In order to evaluate the potential hazards of bacteriemia related to insufflation, we conducted a study in the rat. Two groups of 20 Wistar rats were used for this study. Peritonitis was induced by opening the terminal ileum. Twenty-four hours later, 20 rats were insufflated at a mean pressure of 6 mm Hg (Group I). After one hour of insufflation, an hemoculture was performed via direct intracardiac puncture and in the other group of 20 non-insufflated rats (Group NI). Five of the 18 hemoculture were positive in the Gr. I (27.7%) and 6 out of 20 in the Gr. NI (30%) (chi 2 = 0.238 p = 0.62 non significant difference). These results suggest that insufflation does not facilitate hematogenous dissemination of bacteria from intraperitoneal sepsis in this animal model.
authors.affiliation: Service de Chirurgie, Hôpital Saint-Louis, Paris.
authors.forename: L
authors.initials: L
authors.lastname: Dugue
authors.forename: S
authors.initials: S
authors.lastname: Fritsch
authors.forename: A
authors.initials: A
authors.lastname: Felten
authors.forename: D
authors.initials: D
authors.lastname: Gossot
authors.forename: S
authors.initials: S
authors.lastname: Colomer
authors.forename: M
authors.initials: M
authors.lastname: Celerier
authors.forename: P
authors.initials: P
authors.lastname: Lagrange
authors.forename: Y
authors.initials: Y
authors.lastname: Revillon
mesh_terms: D000818:Animals; D016470:Bacteremia / Q000209:etiology* / Q000382:microbiology; D004195:Disease Models, Animal; D004756:Enterobacteriaceae Infections / Q000209:etiology* / Q000382:microbiology; D007327:Insufflation / Q000009:adverse effects*; D008297:Male; D010538:Peritonitis / Q000601:surgery*; D011027:Pneumoperitoneum / Q000209:etiology* / Q000382:microbiology; D051381:Rats; D017208:Rats, Wistar
vernacular_title: Effets de l'insufflation intra-péritonéale sur la dissémination hématogène des infections abdominales. Résultats préliminaires d'une étude expérimentale chez le rat.