Auditory and somatosensory event-related brain potentials in early blind humans.
Previous event-related potential (ERP) studies have suggested a possible participation of the visual cortex of the blind in auditory processing. In the present study, somatosensory and auditory ERPs of blind and sighted subjects were recorded when subjects were instructed to attend to stimuli of one modality and to ignore those of the other. Both modalities were stimulated with frequent ("standard") and infrequent ("deviant") stimuli, which differed from one another in their spatial locus of origin. In the sighted, deviant stimuli of the attended modality elicited N2 type of deflections (auditory N2b and somatosensory N250) over the lateral scalp areas. In contrast, in the blind, these ERP components were centroposteriorly distributed, suggesting an involvement of posterior brain areas in auditory and somatosensory stimulus discrimination. In addition, the mismatch negativity, elicited by deviant auditory stimuli even when the somatosensory stimuli were attended, was larger in the blind than in the sighted. This appears to indicate enhanced automatic processing of auditory stimulus changes in the blind. Thus, the present data suggest several compensatory changes in both auditory and somatosensory modalities after the onset of early visual deprivation.
Kujala
T
T
Department of Psychology, University of Helsinki, Finland.
Alho
K
K
Kekoni
J
J
Hämäläinen
H
H
Reinikainen
K
K
Salonen
O
O
Standertskjöld-Nordenstam
C G
CG
Näätänen
R
R
D000328:Adult; D001288:Attention / Q000502:physiology; D001766:Blindness / Q000503:physiopathology*; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D011930:Reaction Time / Q000502:physiology