title: Clinical and chest radiographic features of tuberculosis associated with human immunodeficiency virus in Zimbabwe.
abstract: In the developing world, the diagnosis of tuberculosis is dependent on clinical and radiologic features as culture facilities are not readily available. It has been reported that tuberculosis in HIV-positive persons can present with atypical clinical and radiographic features. The object of this study was to examine how often atypical features occur in HIV-positive compared with HIV-negative persons and how these findings correspond to sputum-smear findings. Detailed demographic, clinical, and chest radiographic features of tuberculosis were assessed in 202 HIV-positive adults and 220 HIV-negative patients admitted consecutively. Using univariate analysis, several of these features were found to be significantly associated with being HIV-positive, but after multiple regression analysis only, age group (15 to 42 yr), a negative tuberculin response, intrathoracic lymphadenopathy, and lack of cavitation but not sputum-smear status remained significant.
authors.affiliation: Department of Medicine, University of Zimbabwe, Harare, Zimbabwe.
authors.forename: A L
authors.initials: AL
authors.lastname: Pozniak
authors.forename: G A
authors.initials: GA
authors.lastname: MacLeod
authors.forename: D
authors.initials: D
authors.lastname: Ndlovu
authors.forename: E
authors.initials: E
authors.lastname: Ross
authors.forename: M
authors.initials: M
authors.lastname: Mahari
authors.forename: J
authors.initials: J
authors.lastname: Weinberg
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000175:diagnosis; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D007223:Infant; D016015:Logistic Models; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013183:Sputum / Q000382:microbiology; D014374:Tuberculin Test / Q000706:statistics & numerical data; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis*; D015030:Zimbabwe