title: Aggressive basal cell carcinoma of head and neck areas.
abstract: Among skin cancers, basal cell carcinoma (BCC) is considered as a relatively indolent disease. Sometimes, these carcinomas have an unusual clinical behaviour, with extreme aggressiveness. Based on reports of eight cases of aggressive BCC of the head and neck areas, and after a review of the literature, we define three criteria of aggressiveness: (1) initial diameter greater than 1 cm, (2) more than two recurrences despite all tentative conclusions of adequate treatment, or (3) extension into any extracutaneous structure.
authors.affiliation: Department of Plastic Surgery, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Vico
authors.forename: T
authors.initials: T
authors.lastname: Fourez
authors.forename: E
authors.initials: E
authors.lastname: Nemec
authors.forename: G
authors.initials: G
authors.lastname: Andry
authors.forename: R
authors.initials: R
authors.lastname: Deraemaecker
mesh_terms: D000328:Adult; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery