title: [Preoperative intra-arterial chemotherapy with THP-ADR for locally advanced breast cancer].
abstract: We treated 8 patients of Stage III and IV breast cancer preoperatively with THP-ADR intra-arterial infusion chemotherapy. The median dose was 200 mg with a range from 150 to 310 mg. The response rate of THP was 75.0% compared to 66.7% of ADR. Leucopenia was observed during THP treatment with a lower frequency of alopecia.
authors.affiliation: Dept. of Surgery, Kosei General Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Mukai
authors.forename: T
authors.initials: T
authors.lastname: Fujisaki
authors.forename: N
authors.initials: N
authors.lastname: Sato
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage* / Q000009:adverse effects; D001943:Breast Neoplasms / Q000188:drug therapy*; D004317:Doxorubicin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007970:Leukopenia / Q000139:chemically induced; D008875:Middle Aged; D011300:Preoperative Care
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin; C027260:pirarubicin