title: Cervical lymph node metastasis of thyroid papillary carcinoma imaged with fluorine-18-FDG, technetium-99m-pertechnetate and iodine-131-sodium iodide.
abstract: A 49-yr-old white woman with diffuse sclerosing variant of papillary carcinoma of the thyroid revealed abnormal [18F]FDG accumulation within cervical lymph node metastases prior to thyroidectomy. The abnormal cervical foci of glucose metabolism corresponded to similar areas of abnormal [99mTc]pertechnetate and radioiodine accumulation on presurgical scans. The primary thyroid tumor within the thyroid gland was not delineated as a focal defect on any of the three imaging studies. The relative thyroid-to-background soft-tissue ratio in the [18F]FDG study, however, appeared higher than usual. As with 131I and [99mTc]pertechnetate, this case demonstrates that [18F]FDG PET can detect cervical lymph node metastases in the preoperative thyroid cancer patient.
authors.affiliation: Nuclear Medicine Department, William Beaumont Hospital, Royal Oak, Michigan 48098-1198, USA.
authors.forename: G C
authors.initials: GC
authors.lastname: Scott
authors.forename: D A
authors.initials: DA
authors.lastname: Meier
authors.forename: C Z
authors.initials: CZ
authors.lastname: Dickinson
mesh_terms: D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging* / Q000556:secondary*; D003847:Deoxyglucose / Q000031:analogs & derivatives*; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007457:Iodine Radioisotopes; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009333:Neck; D012974:Sodium Iodide; D013670:Sodium Pertechnetate Tc 99m; D013964:Thyroid Neoplasms / Q000473:pathology*; D014055:Tomography, Emission-Computed
chemical_list: D005462:Fluorine Radioisotopes; D007457:Iodine Radioisotopes; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D013670:Sodium Pertechnetate Tc 99m; D012974:Sodium Iodide