Severe hepatotoxicity from granulocyte-macrophage colony-stimulating factor administered after autologous bone marrow transplantation.
We report a case of life-threatening hepatotoxicity following GM-CSF therapy after autologous bone marrow transplantation. GM-CSF hepatotoxicity should now be considered in the differential diagnosis of post-transplant liver disease.
Prince
H M
HM
University of Toronto Autologous Blood and Marrow Transplant Program, Toronto Hospital, Ontario, Canada.
Cheng
M
M
Cameron
R G
RG
Keating
A
A
D000328:Adult; D016026:Bone Marrow Transplantation; D003937:Diagnosis, Differential; D006084:Graft Rejection / Q000517:prevention & control; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000009:adverse effects*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D014182:Transplantation, Autologous
D016178:Granulocyte-Macrophage Colony-Stimulating Factor