title: Age-related changes in colon motility.
abstract: To assess age-related changes, we analyzed 32 colon manometry studies of children referred for motility studies and found not to have colonic disease. Colon motility was recorded by endoscopically placed water-perfused catheters. There was an inverse correlation between the number of high-amplitude propagated contractions and age, before and after administration of a meal; colonic contractions different from the high-amplitude propagated contractions increased with age.
authors.affiliation: Department of Pediatrics, Harbor-University of California, Los Angeles Medical Center, USA.
authors.forename: C
authors.initials: C
authors.lastname: Di Lorenzo
authors.forename: A F
authors.initials: AF
authors.lastname: Flores
authors.forename: P E
authors.initials: PE
authors.lastname: Hyman
mesh_terms: D000293:Adolescent; D000375:Aging; D002648:Child; D002675:Child, Preschool; D003106:Colon / Q000503:physiopathology*; D003248:Constipation / Q000175:diagnosis / Q000503:physiopathology*; D005215:Fasting; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008365:Manometry; D016735:Munchausen Syndrome by Proxy / Q000503:physiopathology; D013997:Time Factors