title: Methylphenidate in the treatment of neurobehavioral slowing associated with cancer and cancer treatment.
abstract: Psychostimulants used in the treatment of psychiatric conditions, including depression, alleviate some of the observed psychomotor retardation. We describe 3 patients with impairments of arousal and psychomotor speed secondary to tumor-related organic brain dysfunction who benefited from stimulant therapy.
authors.affiliation: Department of Neuro-Oncology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Weitzner
authors.forename: C A
authors.initials: CA
authors.lastname: Meyers
authors.forename: A D
authors.initials: AD
authors.lastname: Valentine
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001143:Arousal / Q000187:drug effects; D001254:Astrocytoma / Q000150:complications / Q000628:therapy; D001288:Attention / Q000187:drug effects; D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology / Q000628:therapy; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D005260:Female; D005909:Glioblastoma / Q000150:complications / Q000628:therapy; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology* / Q000523:psychology; D008774:Methylphenidate / Q000627:therapeutic use*; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011878:Radiotherapy / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents; D000697:Central Nervous System Stimulants; D008774:Methylphenidate