title: Parvovirus B19 infection in hospital workers: community or hospital acquisition?
abstract: A suspected nosocomial outbreak of parvovirus B19 infection in a maternity ward was investigated in February 1994. Questionnaires were administered and sera collected from maternity ward staff (n = 91), other ward staff in the same hospital (n = 101), and maternity ward staff at a nearby hospital (n = 81). Blood donors (n = 265) were used as community controls. Recent infection (parvovirus B19 IgM positivity) in susceptible persons (parvovirus B19 IgG-negative or IgM-positive) was common among all 4 groups (23%-30%). This high rate of recent infection occurred during a large community outbreak of fifth disease. Environmental samples collected from a room where a stillborn parvovirus B19-infected fetus was delivered were positive for parvovirus B19 DNA. Thus, this suspected nosocomial outbreak actually reflected transmission outside the hospital, but contaminated environmental surfaces were identified as one potential source for transmission of parvovirus B19.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
authors.forename: S F
authors.initials: SF
authors.lastname: Dowell
authors.forename: T J
authors.initials: TJ
authors.lastname: Török
authors.forename: J A
authors.initials: JA
authors.lastname: Thorp
authors.forename: J
authors.initials: J
authors.lastname: Hedrick
authors.forename: D D
authors.initials: DD
authors.lastname: Erdman
authors.forename: S R
authors.initials: SR
authors.lastname: Zaki
authors.forename: C J
authors.initials: CJ
authors.lastname: Hinkle
authors.forename: W L
authors.initials: WL
authors.lastname: Bayer
authors.forename: L J
authors.initials: LJ
authors.lastname: Anderson
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D002487:Centers for Disease Control and Prevention, U.S.; D017714:Community-Acquired Infections; D003428:Cross Infection; D004196:Disease Outbreaks; D004487:Edema; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D016731:Erythema Infectiosum / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D005260:Female; D005313:Fetal Death; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008923:Missouri / Q000453:epidemiology; D009775:Obstetrics and Gynecology Department, Hospital; D010564:Personnel, Hospital; D011247:Pregnancy; D014481:United States
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M