Interferons: their role in clinical practice.
OBJECTIVE
To describe the current indications and side effects of Interferons in the treatment of human disease together with sufficient background information to understand the rationale for their use.


METHODS
Literature searches on interferons extended back to the time of their discovery. Citations were limited to English and human aspects. Reference lists from recent reviews were also consulted.


METHODS
Reviews of fundamental mechanisms were selected together with studies of individual clinical trials and anecdotal experiences with human use of interferons.


CONCLUSIONS
Interferons are accepted therapy for a number of conditions. Their range of therapeutic uses will undoubtedly increase as further knowledge is obtained.
Ucar
R
R
Division of Allergy and Clinical Immunology, Harbor-UCLA Medical Center, Torrance, USA.
Sanwo
M
M
Ucar
K
K
Beall
G
G
D004347:Drug Interactions; D006801:Humans; D007372:Interferons / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*
D007372:Interferons