Localization of IGF1R and EDN genes to pig chromosomes 1 and 7 by in situ hybridization.
The genes coding for the insulin-like growth factor-1 receptor (IGF1R) and a porcine endothelium-derived 21-residue vasoconstrictor peptide (EDN) were localized in the pig by means of radioactive in situ hybridization. IGF1R was mapped to chromosome region 1q1.7-->q2.1 and EDN to 7p1.3-->p1.2. The results are discussed in relation to the position of their homologous loci in man.
Lahbib-Mansais
Y
Y
Laboratoire de Génétique Cellulaire, Centre INRA Toulouse, Castanet-Tolosan, France.
Yerle
M
M
Gellin
J
J
D000818:Animals; D002874:Chromosome Mapping; D019332:Endothelin-1; D016232:Endothelins / Q000235:genetics*; D006801:Humans; D017403:In Situ Hybridization; D011498:Protein Precursors / Q000235:genetics*; D017526:Receptor, IGF Type 1 / Q000235:genetics*; D013552:Swine / Q000235:genetics*; D014661:Vasoconstriction / Q000235:genetics*
D019332:Endothelin-1; D016232:Endothelins; D011498:Protein Precursors; D017526:Receptor, IGF Type 1