[Study of the nature and mechanism of action of virus neutralizing inhibitors of the blood].
Low-density lipoproteins (LDL, d 1.0.40-1.053 g/ml) and high-density lipoproteins (subfraction 3 of HDL, d 1.210 g/ml) were isolated by preparative ultracentrifugation at the NaBr density gradient. The findings have led to the conclusion that LDL or beta-LP are not thermolabile, but they represent a thermoresistant serum virus-inhibiting factor. At the same time HDL3 has pronounced thermolabile properties. The mechanisms of action of the above factors are explained in the paper.
Pleskov
V M
VM
Bannikov
A I
AI
D000818:Animals; D000998:Antiviral Agents; D001055:Apolipoproteins B / Q000097:blood / Q000502:physiology; D001798:Blood Proteins / Q000502:physiology*; D002478:Cells, Cultured; D002499:Centrifugation, Density Gradient; D006387:Hemagglutination, Viral; D006801:Humans; D007106:Immune Sera; D009980:Influenza A virus / Q000276:immunology*; D008074:Lipoproteins / Q000097:blood* / Q000302:isolation & purification / Q000502:physiology*; D008075:Lipoproteins, HDL / Q000097:blood / Q000302:isolation & purification / Q000502:physiology; D008077:Lipoproteins, LDL / Q000097:blood / Q000302:isolation & purification / Q000502:physiology; D011233:Precipitin Tests; D011817:Rabbits; D013696:Temperature
D000998:Antiviral Agents; D001055:Apolipoproteins B; D001798:Blood Proteins; D007106:Immune Sera; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL
Izuchenie prirody i mekhanizma deĭstviia virusneitralizuiushchikh ingibitorov syvorotki krovi.