title: Features of cocaine dependence with concurrent alcohol abuse.
abstract: In order to assess differences between cocaine dependence alone and cocaine dependence complicated by alcohol abuse, 34 subjects who met DSM-III-R criteria for alcohol abuse and cocaine dependence (COC-ETOH group) were compared with 39 subjects who met criteria for cocaine dependence only (COC-only group) with regard to demographics, substance use, and psychopathology. There were no differences between groups in age, race, employment or socio-economic status. The baseline depression and global severity scores in the COC-ETOH group were significantly higher than in the COC-only group. The COC-ETOH group was significantly more likely to experience a paranoid psychosis with cocaine use and significantly more likely to have abused additional substances in the month prior to study entry. The COC-ETOH group also attended significantly fewer medication management sessions during the 12-week trial. There were no differences between groups in the type or frequency of Axis 1 or Axis II disorders.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29426, USA.
authors.forename: K T
authors.initials: KT
authors.lastname: Brady
authors.forename: S
authors.initials: S
authors.lastname: Sonne
authors.forename: C L
authors.initials: CL
authors.lastname: Randall
authors.forename: B
authors.initials: B
authors.lastname: Adinoff
authors.forename: R
authors.initials: R
authors.lastname: Malcolm
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation; D002220:Carbamazepine / Q000627:therapeutic use; D003042:Cocaine; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology; D011605:Psychoses, Substance-Induced / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000534:rehabilitation; D016896:Treatment Outcome
chemical_list: D002220:Carbamazepine; D003042:Cocaine