[Epidemiological data. Neonatal and prenatal screening].
Unlike what is generally thought, cystic fibrosis is not the most frequent hereditary disease. Its frequency is approximately 1/3 200 and varies with the geographic area. The frequency of heterozygous subjects is about 1/28. No country has established a generalized neonatal screening programme, for technical reasons and because there has been no demonstration of a beneficial effect from early care. It would nevertheless be useful to develop experimental programmes defining which protocols might best be established. Antenatal screening can be based on detecting heterozygous subjects, a technically feasible operation, although answers to a large number of questions would be required.
Farriaux
J P
JP
Service de Pédiatrie, Hôpital Huriez, CHU, Lille.
Dhondt
J L
JL
D003550:Cystic Fibrosis / Q000453:epidemiology* / Q000235:genetics / Q000517:prevention & control; D005260:Female; D005602:France / Q000453:epidemiology; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D008403:Mass Screening / Q000379:methods; D011247:Pregnancy; D011296:Prenatal Diagnosis
Données épidémiologiques. Dépistage néo- et anténatal.