title: [The use of leukinferon in treating measles in adult patients].
abstract: The following mucosal are characteristic of measles in adult patients: dryness in the oral cavity, dryness, desquamation, and fissures in the red edge and in the mouth corners, edema and hyperemia, of the buccal mucosa, macular enanthema on the hard and soft palate, Bel'skiĭ-Filatov-Koplik spots, whitish deposit on the gingiva, edematous and bleeding gingiva, and, as a result of general intoxication, a lingual deposit. Leukinferon, a wide-spectrum immunocorrective drug, was used to improve the efficacy of treatment of adult patients with measles; besides alpha-interferon, it contains other cytokines of the first phase of immune response. Therapy with leukinferon led to a sooner improvement of the general status and a more rapid regression of the disease symptoms, including changes in the buccal mucosa, in comparison with the control leukinferon-untreated group.
authors.forename: I N
authors.initials: IN
authors.lastname: Nikolaeva
authors.forename: V P
authors.initials: VP
authors.lastname: Kuznetsov
authors.forename: G M
authors.initials: GM
authors.lastname: Barer
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
authors.forename: D L
authors.initials: DL
authors.lastname: Beliaev
authors.forename: O V
authors.initials: OV
authors.lastname: Sinitsyna
authors.forename: A A
authors.initials: AA
authors.lastname: Babaiants
authors.forename: N D
authors.initials: ND
authors.lastname: Iushchuk
mesh_terms: D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D016207:Cytokines / Q000008:administration & dosage*; D004338:Drug Combinations; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007370:Interferon Type I / Q000008:administration & dosage*; D008297:Male; D008457:Measles / Q000150:complications / Q000188:drug therapy*; D009059:Mouth Diseases / Q000188:drug therapy / Q000209:etiology; D009067:Mouthwashes
chemical_list: D000276:Adjuvants, Immunologic; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; D009067:Mouthwashes; C062252:leukinferon
vernacular_title: Primenenie leĭkinferona pri lechenii kori u vzroslykh bol'nykh.