title: Normal serum biochemical and hematological values of the Sulawesi macaques.
abstract: Sulawesi macaque (SM) species are currently of interest to primatologists for genetic and behavioral studies world wide. However, there are no published reference hematological and serum biochemical profile values for several of the seven SM species. Twenty-five clinically healthy, outdoor housed, ketamine sedated Macaca tonkeana and Macaca maurus were serially sampled (two to four times) over a 16-month period (N = 68). Normal ranges were defined to include two standard deviations and 2.5-97.5 percentile. Significant differences in single sample data comparisons (P < 0.05) of species (serum Ca, MCHC), age (BUN, BUN/creatinine, alkaline phosphatase, phosphorus), gender (total protein, RBC, hemoglobin, HCT) and pregnancy (phosphorus and neutrophil count) groups were found. This normative data facilitates clinical evaluation of SM species and allows comparison to other macaque species.
authors.affiliation: Department of Comparative Medicine, Medical University of South Carolina, Charleston, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Goodrich
authors.forename: G S
authors.initials: GS
authors.lastname: Ward
authors.forename: M M
authors.initials: MM
authors.lastname: Swindle
mesh_terms: D000375:Aging / Q000097:blood; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary*; D001798:Blood Proteins / Q000032:analysis; D001806:Blood Urea Nitrogen; D002118:Calcium / Q000097:blood; D003404:Creatinine / Q000097:blood; D004573:Electrolytes / Q000097:blood; D004798:Enzymes / Q000097:blood; D004906:Erythrocyte Count; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D008251:Macaca / Q000097:blood*; D008297:Male; D011247:Pregnancy; D012016:Reference Values; D012727:Sex Characteristics; D013045:Species Specificity
chemical_list: D001798:Blood Proteins; D004573:Electrolytes; D004798:Enzymes; D006454:Hemoglobins; D003404:Creatinine; D002118:Calcium