title: Promethazine toxicity in a seven-month-old Doberman pinscher.
abstract: A 7-mo-old female Doberman Pinscher undergoing antibiotic treatment for tonsillitis was presented in near collapse with markedly low blood pressure, tachycardia, dilatation of pupils (non-responsive to light), and gastrointestinal distress. Since the owner could provide no history of significant toxin exposure, general supportive and non-specific toxicologic treatment protocols were initiated. Within 4 h marked improvement was observed. The owner's wife revealed that promethazine suppositories had been administered at a toxic level to control the vomition accompanying the tonsillitis.
authors.affiliation: Veterinary Medical Clinic, Alamogordo, NM 88310, USA.
authors.forename: E C
authors.initials: EC
authors.lastname: Staley
authors.forename: E E
authors.initials: EE
authors.lastname: Staley
mesh_terms: D000285:Administration, Rectal; D000818:Animals; D000932:Antiemetics / Q000008:administration & dosage / Q000506:poisoning*; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D062787:Drug Overdose; D005260:Female; D008199:Lymphadenitis / Q000662:veterinary; D011398:Promethazine / Q000008:administration & dosage / Q000506:poisoning*; D013488:Suppositories; D014069:Tonsillitis / Q000662:veterinary; D014839:Vomiting / Q000139:chemically induced / Q000662:veterinary*
chemical_list: D000932:Antiemetics; D013488:Suppositories; D011398:Promethazine