Low CD4 lymphocyte count in a patient with P. carinii pneumonia after autologous bone marrow transplantation.
Authors report a case of P. carinii pneumonia in a child with 5% CD4 lymphocytes (absolute number 5/microliters) after autologous bone marrow transplantation followed by pulmonary irradiation. Serial evaluation of CD4 lymphocyte count or percentage or, at least, detection of significant and persistent lymphopenia could be useful for detecting a high risk of developing P. carinii pneumonia.
Castagnola
E
E
Department of Infectious Diseases, G Gaslini Children's Hospital, Genova, Italy.
Dini
G
G
Lanino
E
E
Tasso
L
L
Dallorso
S
S
Garaventa
A
A
Rossi
G A
GA
Giacchino
R
R
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000276:immunology*; D018791:CD4 Lymphocyte Count; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004198:Disease Susceptibility; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary / Q000628:therapy; D011020:Pneumonia, Pneumocystis / Q000276:immunology*; D011658:Pulmonary Fibrosis / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D012186:Retroperitoneal Neoplasms / Q000188:drug therapy / Q000628:therapy