Treatment of complex partial status epilepticus unmasking acute intermittent porphyria in a patient with resected anaplastic glioma.
We report a 42-year-old woman with an established complex partial seizure disorder, who presented in refractory complex partial status epilepticus, the treatment of which with lorazepam, phenytoin, carbamazepine, and pentobarbital precipitated an attack of acute intermittent porphyria (AIP). The subsequent clinical course and management with gabapentin is discussed.
Yandel
M L
ML
Department of Medicine, Tripler Army Medical Center, Honolulu, HI 96859, USA.
Watters
M R
MR
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D001932:Brain Neoplasms / Q000601:surgery*; D003693:Delirium / Q000209:etiology; D003937:Diagnosis, Differential; D017029:Epilepsy, Complex Partial / Q000188:drug therapy*; D005260:Female; D005625:Frontal Lobe / Q000601:surgery; D005909:Glioblastoma / Q000601:surgery*; D006801:Humans; D017118:Porphyria, Acute Intermittent / Q000139:chemically induced*; D011183:Postoperative Complications / Q000188:drug therapy*; D013226:Status Epilepticus / Q000188:drug therapy*; D013702:Temporal Lobe / Q000601:surgery
D000927:Anticonvulsants