title: [Analgesia with intra-articular injection of buprenorphine after surgery of the shoulder].
abstract: The effect of 10 ml of intra-articular buprenorphine (0.30 mg) or normal saline on postoperative pain after shoulder surgery was studied in a randomized, prospective, double-blind study in 30 ASA I-II patients receiving general anaesthesia. The pain scores (Five Point Scale ranging from "no pain" to "unbearable pain" and Visual Analog Pain Scale) 1, 2, 3, 4, 6 and 24 hours after surgery, time to first analgesic use and total 6-hours and 24-hours analgesic requirements were recorded. VAPS was significantly lower in the buprenorphine group compared with placebo-treated patients one hour after surgery (p < 0.05). The time to first analgesic use was longer and total 6-h opioid requirements were lower in the buprenorphine group when compared with the control group (p < 0.05). No significant differences were detected in total 24-h analgesic requirements between the two groups. These results indicate that intra-articular injection of buprenorphine after shoulder surgery provides short analgesia. This effect may be mediated by systemic absorption.
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Purpan, Toulouse.
authors.forename: J L
authors.initials: JL
authors.lastname: Fellahi
authors.forename: J P
authors.initials: JP
authors.lastname: Magues
authors.forename: B
authors.initials: B
authors.lastname: Marquer
authors.forename: A
authors.initials: A
authors.lastname: Guérot
authors.forename: M
authors.initials: M
authors.lastname: Mansat
authors.forename: B
authors.initials: B
authors.lastname: Cathala
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002047:Buprenorphine / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D004204:Joint Dislocations / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D012785:Shoulder Joint; D012965:Sodium Chloride / Q000008:administration & dosage
chemical_list: D000700:Analgesics; D000701:Analgesics, Opioid; D002047:Buprenorphine; D012965:Sodium Chloride
vernacular_title: Analgésie par injection intra-articulaire de buprénorphine après chirurgie de l'épaule.