[The heterogeneity of the reaction of plasma renin activity in the arterial blood of rats to acetylcholine infusion into the systemic blood flow].
I.v. administration of acetylcholine in anesthetised rats with a preliminary adrenoblockade decreased the plasma renin activity (PRA) of arterial blood in rats with an increased sympathetic reactivity and a high sensitivity to acetylcholine. The PRA did not change in the rats with a high adrenergic effect on the PRA. The data suggests that the PRA response to acetylcholine depends on sympatho-parasympathetic interaction.
Fedorov
V I
VI
Bonetskiĭ
A A
AA
D000109:Acetylcholine / Q000008:administration & dosage* / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001158:Arteries; D001794:Blood Pressure / Q000187:drug effects; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D007262:Infusions, Intravenous; D007601:Jugular Veins; D008297:Male; D008790:Metoprolol / Q000494:pharmacology; D010424:Pentobarbital / Q000494:pharmacology; D051381:Rats; D012083:Renin / Q000097:blood* / Q000187:drug effects*; D012084:Renin-Angiotensin System / Q000187:drug effects; D013312:Stress, Physiological / Q000097:blood / Q000503:physiopathology
D000319:Adrenergic beta-Antagonists; D012083:Renin; D008790:Metoprolol; D010424:Pentobarbital; D000109:Acetylcholine; D004837:Epinephrine
Neodnorodnost' reaktsii aktivnosti renina plazmy arterial'noĭ krovi u krys na infuziiu atsetilkholina v sistemnyĭ krovotok.