Using computerized individual medication data to detect drug effects on clinical laboratory tests.
In clinical practice, thousands of drugs are used daily. Clinicians know the therapeutic effects of drugs but other minor drug effects are often ignored either because of inadequate knowledge of these effects or simply because of the limited memory capacity of a human being. This problem can be solved by using a computerized information system, which includes medication data of individual patients as well as information about non-therapeutic drug-effects. One of these non-therapeutic confusing drug effects is the influence of drugs on laboratory tests; a problem that should be taken into account in clinical practice and diagnostics. Other complicating drug effects include drug interactions and patient related adverse drug reactions. In a computerized information system, it is possible to build decision support modules that automatically give alarms or alerts of important drug effects other than therapeutic effects. If these warnings concern laboratory tests they are checked by a laboratory physician and only those with clinical significance are sent to clinicians. Warnings of drug interactions and adverse drug reactions are immediately evaluated by the physician responsible for the treatment. By means of the computerized information system, it is also possible to get better information of current medication practice which in turn gives better chances to agree on common guidelines and enables better quality assurance.
Grönroos
P
P
Central Laboratory, Turku University Central Hospital, Finland.
Irjala
K
K
Heiskanen
J
J
Torniainen
K
K
Forsström
D016907:Adverse Drug Reaction Reporting Systems; D019411:Clinical Laboratory Techniques / Q000592:standards*; D003199:Computer Systems; D016208:Databases, Factual; D004347:Drug Interactions; D016903:Drug Monitoring; D006801:Humans; D008510:Medication Systems, Hospital; D011786:Quality Control