title: Multicellular resistance: a new paradigm to explain aspects of acquired drug resistance of solid tumors.
authors.affiliation: Division of Cancer Research, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
authors.forename: R S
authors.initials: RS
authors.lastname: Kerbel
authors.forename: J
authors.initials: J
authors.lastname: Rak
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: M S
authors.initials: MS
authors.lastname: Man
authors.forename: B
authors.initials: B
authors.lastname: St Croix
authors.forename: C H
authors.initials: CH
authors.lastname: Graham
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology; D015815:Cell Adhesion Molecules / Q000502:physiology; D002470:Cell Survival / Q000187:drug effects; D004351:Drug Resistance; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D010641:Phenotype; D018874:Spheroids, Cellular / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
chemical_list: D018906:Antineoplastic Agents, Alkylating; D015815:Cell Adhesion Molecules