title: Phenotype and cancer risk of various polyposis syndromes.
abstract: The gastrointestinal polyposis syndromes are disorders with multiple intestinal polyps. Three of these disorders, familial adenomatous polyposis, Peutz-Jeghers syndrome and juvenile polyposis are associated with increased risk of colorectal as well as extracolonic cancers. A description of the phenotype and associated cancer risk is provided for each.
authors.affiliation: Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
authors.forename: F M
authors.initials: FM
authors.lastname: Giardiello
authors.forename: J G
authors.initials: JG
authors.lastname: Offerhaus
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000235:genetics; D000367:Age Factors; D015179:Colorectal Neoplasms / Q000209:etiology; D005770:Gastrointestinal Neoplasms / Q000235:genetics*; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics*; D010580:Peutz-Jeghers Syndrome / Q000235:genetics; D010641:Phenotype