Effects of dietary vitamin D intake on plasma levels of parathyroid hormone and vitamin D metabolites in healthy Japanese.
To clarify the nutritional status of vitamin D in Japanese, effects of dietary intake of vitamin D on plasma levels of intact and highly sensitive parathyroid hormone (I-PTH and HS-PTH), 25-hydroxyvitamin D (25-OH-D), 1,25-dihydroxyvitamin D (1,25(OH)2D), calcium (Ca) and phosphorus (P(i)) in 79 healthy Japanese were investigated. The plasma levels of 25-OH-D in men were significantly higher than those in women, whereas those of HS-PTH in men were significantly lower than those in women. The levels of 25-OH-D in men were generally higher than those in women. Significant correlations were observed between the dietary vitamin D intake and the plasma 25-OH-D or HS-PTH levels. Correlations between the plasma 25-OH-D levels and the plasma HS-PTH levels were also significant. These results suggest that dietary intake of sufficient amounts of vitamin D is effective for improving the vitamin D nutritional status through normalizing PTH levels.
Takeuchi
A
A
Department of Hygienic Sciences, Kobe Pharmaceutical University, Japan.
Okano
T
T
Ishida
Y
Y
Kobayashi
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002117:Calcitriol / Q000097:blood*; D002118:Calcium / Q000097:blood / Q000494:pharmacology*; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood*; D007564:Japan; D008297:Male; D009752:Nutritional Status; D010281:Parathyroid Hormone / Q000097:blood*; D010758:Phosphorus / Q000097:blood; D012016:Reference Values; D014807:Vitamin D / Q000494:pharmacology*
D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D014807:Vitamin D; D010758:Phosphorus; D002117:Calcitriol; D002118:Calcium