Age at menarche among diethylstilbestrol granddaughters.
We interviewed 542 women whose mothers were in a randomized trial of diethylstilbestrol. Effects of diethylstilbestrol on the third generation were explored by ascertaining age at menarche for the women's daughters. A total of 123 daughters were > or = 10 years old (52 exposed and 71 unexposed). Age at menarche was unaffected by mother's prenatal diethylstilbestrol exposure.
Wilcox
A J
AJ
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Umbach
D M
DM
Hornsby
P P
PP
Herbst
A L
AL
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D004054:Diethylstilbestrol / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008572:Menarche; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D016032:Randomized Controlled Trials as Topic
D004054:Diethylstilbestrol