[Plasmids of antibiotic-resistant strains of Salmonella of varying origin, circulating the Saint-Petersburg and Leningrad region].
Two hundred and twenty Salmonella strains of various serovars isolated from different source in St. Petersburg and the Leningrad Region in 1984-1991 were investigated. It was shown that drug resistance in 39.3 per cent of the strains was determined by conjugative R plasmids with the molecular weights of 28 to 90 mD which transferred at a rate of 10(-4) to 10(-8). Thirteen detected types of the Salmonella conjugative R plasmids differing in the resistance markers, molecular weights and conjugative transfer rates most frequently contained the genes responsible for the resistance to tetracycline (97.7 per cent), chloramphenicol (92.0 per cent), streptomycin (83.0 per cent), kanamycin (76.1 per cent), monomycin (76.1 per cent) and neomycin (76.1 per cent). The conjugative R plasmids were mainly detected in S> typhimurium (92.9 per cent), especially in the isolates from humans (97.6 per cent). The most frequent plasmid type in the Salmonella strains of this serovar was that with the molecular weight of 90 mD carrying the genes of resistance to chloramphenicol, tetracycline, streptomycin, kanamycin, monomycin and neomycin.
Kozlova
N S
NS
Ivanov
V P
VP
Kuz'min
V A
VA
Lipatova
L A
LA
Gladin
D P
DP
D004352:Drug Resistance, Microbial / Q000235:genetics; D005798:Genes, Bacterial; D008970:Molecular Weight; D010641:Phenotype; D011815:R Factors / Q000235:genetics*; D012426:Russia; D012475:Salmonella / Q000235:genetics*
Plazmidy antibiotikorezistentnykh shtammov sal'monell razlichnogo proiskhozhdeniia, tsirkuliruiushchikh v Sankt-Peterburge i Leningradskoĭ oblasti.