No effect of an alpha-glucosidase inhibitor on glucose metabolism in patients with non-insulin-dependent diabetes mellitus and low function of pancreatic beta cells.
Twenty patients with non-insulin-dependent diabetes mellitus who had been receiving appropriate dietary treatment for 3 months but whose glucose metabolism needed further improvement were treated with an alpha-glucosidase inhibitor. Treatment with the alpha-glucosidase inhibitor (0.6 mg/day) for 4 weeks, had no significant effect on blood glucose levels 2 h after breakfast or on glycosylated haemoglobin levels.
Okada
S
S
Third Department of Internal Medicine, Okayama University Medical School, Japan.
Ishii
K
K
Tanokuchi
S
S
Hamada
H
H
Ichiki
K
K
Ota
Z
Z
D001786:Blood Glucose / Q000032:analysis; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D006442:Glycated Hemoglobin / Q000032:analysis; D065089:Glycoside Hydrolase Inhibitors; D006801:Humans; D007515:Islets of Langerhans / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D005947:Glucose; D006442:Glycated Hemoglobin; D065089:Glycoside Hydrolase Inhibitors