[Hepatitis C virus viremia and Herpes zoster virus infection in a patient in hemodialysis treated with erythropoietin].
Hepatitis C virus infection in chronic hemodialysis patients is associated with several unresolved problems. We report a 85 years old female patient in chronic hemodialysis and treated with erythropoietin, that during the course of an Herpes zoster, presented severe malaise, weight loss and muscle weakness. Two weeks later, a slight rise in serum transaminases was detected. The patient had negative antibodies for HIV and hepatitis C virus and negative hepatitis B surface antigen. A PCR test was positive for serum hepatitis C virus RNA. The patient's condition deteriorated and she died 7 days after admission. Erythropoietin administration, whose immunosuppressive effect has been reported previously, could have influenced the dismal outcome of this patient.
Duclos
J
J
Departamento de Nefrología, Hospital Naval, Viña del Mar, Chile.
D000368:Aged; D000369:Aged, 80 and over; D004921:Erythropoietin / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006526:Hepatitis C / Q000150:complications* / Q000209:etiology; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000150:complications / Q000628:therapy; D065227:Transfusion Reaction; D014766:Viremia / Q000150:complications*
D004921:Erythropoietin
Viremia VHC e infección por virus Herpes zoster en un paciente en hemodiálisis tratada con eritropoietina.