title: Systemic reactions to the Samsum ant: an IgE-mediated hypersensitivity.
abstract: BACKGROUND
  In the United Arab Emirates the sting of the Pachycondyla sennaarensis ant (PSA) causes allergic reactions in certain persons. It is a common problem and is becoming a public health hazard. Up to now the diagnosis has been based only on the history, because the mechanism of the reaction was not yet established.
  
  
  OBJECTIVE
  The aim of our study was to prepare an allergenic extract that would be used for skin tests and to prepare a reagent for specific IgE titration. Results of both skin tests and specific IgE were to be compared with the clinical history.
  
  
  METHODS
  We studied 31 patients with anaphylactic reactions and performed clinical examinations, skin tests, and specific IgE antibody titrations. A control group of 22 subjects were also studied.
  
  
  RESULTS
  In 30 of 31 patients (97%) findings of PSA skin tests and/or specific IgE were positive. In the control groups PSA skin test results were negative in 86% and negative for specific IgE in 68%.
  
  
  CONCLUSIONS
  The study shows that the mechanism of the reaction to the sting of the PSA is a type I IgE-mediated hypersensitivity and that the diagnosis can now be confirmed by skin tests and specific IgE determination.
authors.affiliation: Department of Medicine, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates.
authors.forename: G
authors.initials: G
authors.lastname: Dib
authors.forename: B
authors.initials: B
authors.lastname: Guerin
authors.forename: W A
authors.initials: WA
authors.lastname: Banks
authors.forename: F
authors.initials: F
authors.lastname: Leynadier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001000:Ants / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology*; D007299:Insect Bites and Stings / Q000276:immunology*; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E