title: Bleomycin sclerotherapy in patients with congenital lymphatic malformation in the head and neck.
abstract: Congenital lymphatic malformations of the head and neck often present challenging problems to the otolaryngologist-head and neck surgeon. Although surgical excision was agreed to be the treatment of choice for this disease, the infiltrating nature of lymphatic channels often increases the frequency of operative complications and recurrences of this lesion.
  
  
  OBJECTIVE
  Bleomycin sclerotherapy was attempted to avoid surgical risk and to cure this lesion.
  
  
  METHODS
  Clinical findings and treatment results were reviewed for patients with congenital lymphatic malformation and treated by bleomycin sclerotherapy.
  
  
  RESULTS
  Bleomycin sclerotherapy was a very effective therapeutic alternative. The best results were seen in cystic type 1 lesions in younger patients.
  
  
  CONCLUSIONS
  Bleomycin sclerotherapy is a useful medical alternative, and we believe that it should be attempted before excision of the lesion.
authors.affiliation: Department of Otolaryngology, Seoul National University, College of Medicine, Korea.
authors.forename: M W
authors.initials: MW
authors.lastname: Sung
authors.forename: S O
authors.initials: SO
authors.lastname: Chang
authors.forename: J H
authors.initials: JH
authors.lastname: Choi
authors.forename: J Y
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006257:Head / Q000473:pathology; D006258:Head and Neck Neoplasms / Q000151:congenital* / Q000188:drug therapy* / Q000473:pathology; D006391:Hemangioma / Q000151:congenital* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009333:Neck / Q000473:pathology; D015911:Sclerotherapy; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D001761:Bleomycin