title: [Portal thrombosis and liver cirrhosis. Value of ultrasound-guided puncture-biopsy of the thrombus].
abstract: OBJECTIVE
  Portal vein thrombosis which occurs in the course of cirrhosis, associated or not with hepatocellular carcinoma, can be either cruoric or neoplastic. The aim of this study was to assess the feasibility and the results of ultrasound guided biopsy of portal vein thrombosis in 21 patients with cirrhosis (20 men and 1 woman; mean age 66 +/- 9 years), who were hospitalized between May 1989 and November 1993. Ultrasound guided biopsies of the cirrhotic liver, of the portal vein thrombosis and, when present, of a hepatic nodular lesion were performed. The diagnosis of hepatocellular carcinoma was made if the histological examination of the hepatic and portal biopsy samples were positive or if serum concentrations of alpha-fetoprotein were higher than 500 IU/mL.
  
  
  RESULTS
  All portal vein thrombosis biopsies were successfully performed. No side-effects were observed. Before ultrasound guided biopsy of the portal thrombosis, diagnosis of hepatocellular carcinoma was made in 15 cases, and diagnosis of cirrhosis in 6 cases. After histological examination of the portal sample, hepatocellular carcinoma was diagnosed in 19 cases and cirrhosis in 2 cases. Thus, in 19% of cases, ultrasound guided biopsy of the portal thrombus provided a definitive diagnosis.
  
  
  CONCLUSIONS
  Ultrasound guided biopsy of the portal vein thrombosis must be performed before liver transplantation for cirrhosis or hepatocellular carcinoma to exclude the presence of a vascular neoplastic extension.
authors.affiliation: Service d'Hépato-Gastroentérologie, Centre Hospitalier Universitaire Nord, Amiens.
authors.forename: J C
authors.initials: JC
authors.lastname: Duchmann
authors.forename: J P
authors.initials: JP
authors.lastname: Joly
authors.forename: J P
authors.initials: JP
authors.lastname: Biny
authors.forename: H
authors.initials: H
authors.lastname: Sevestre
authors.forename: J P
authors.initials: JP
authors.lastname: Capron
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging* / Q000473:pathology; D011446:Prospective Studies; D013927:Thrombosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D014463:Ultrasonography
vernacular_title: Thrombose portale et cirrhose. Intérêt de la ponction-biopsie échoguidée du thrombus.