title: World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine)
abstract: The first edition of the W.A.A.V.P. anthelmintic guidelines for ruminants was published in 1982. Since then improved parasitological procedures have been developed, new therapeutic and prophylactic products have appeared requiring different test methods, and registration authorities are requesting more detailed record keeping and data validation. This second edition addresses these developments and fulfills the original goal of publishing guidelines for high quality, scientifically valid testing standards for trials that would be accepted as proof of efficacy by registration authorities regardless of country of origin. This second edition includes updated guidance on standard parasitological procedures, dose titration, dose confirmation and clinical trials, and provides guidelines for evaluating products for efficacy against anthelmintic resistant parasites, persistence of activity and prophylactic activity. Tests for efficacy against nematodes, trematodes and cestodes are included.
authors.affiliation: Department of Veterinary Parasitology, Veterinary School, Glasgow, UK.
authors.forename: I B
authors.initials: IB
authors.lastname: Wood
authors.forename: N K
authors.initials: NK
authors.lastname: Amaral
authors.forename: K
authors.initials: K
authors.lastname: Bairden
authors.forename: J L
authors.initials: JL
authors.lastname: Duncan
authors.forename: T
authors.initials: T
authors.lastname: Kassai
authors.forename: J B
authors.initials: JB
authors.lastname: Malone
authors.forename: J A
authors.initials: JA
authors.lastname: Pankavich
authors.forename: R K
authors.initials: RK
authors.lastname: Reinecke
authors.forename: O
authors.initials: O
authors.lastname: Slocombe
authors.forename: S M
authors.initials: SM
authors.lastname: Taylor
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000517:prevention & control; D005260:Female; D015511:Goat Diseases / Q000188:drug therapy / Q000517:prevention & control; D006041:Goats; D006373:Helminthiasis / Q000188:drug therapy / Q000517:prevention & control; D006374:Helminthiasis, Animal; D008297:Male; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000592:standards / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000517:prevention & control
chemical_list: D000871:Anthelmintics