Ultrastructural relation between nerve terminals and dentine bridge formation after pulpotomy in human teeth.
Close association between nerve terminals and preodontoblasts, odontoblasts and predentine was observed during healing after pulpotomy. The nerve terminals frequently contained large numbers of synaptic vesicles. Terminals with many vesicles tended to be fewer in the predentine than in the odontoblastic layer. The distribution of terminals was more dense at the stage before the regenerated odontoblasts became arranged regularly beneath the predentine. It is suggested that these terminals have some efferent role(s), especially during collagen synthesis at the early stage of dentinogenesis. The nerves may release their abundant synaptic vesicles, in addition to serving a sensory role for monitoring the increased sensitivity in the injured areas.
Inoue
H
H
First Department of Conservative Dentistry, Fukuoka Dental College, Japan.
Taniguchi
K
K
Okamura
K
K
Izumi
T
T
Tamura
N
N
Kajiwara
S
S
Yamada
K
K
Kuroda
E
E
Watanabe
K
K
Kitamura
K
K
D003809:Dentin, Secondary / Q000254:growth & development / Q000294:innervation*; D003810:Dentinogenesis / Q000502:physiology*; D006801:Humans; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000648:ultrastructure; D009804:Odontoblasts / Q000648:ultrastructure; D011672:Pulpotomy; D013572:Synaptic Vesicles / Q000648:ultrastructure; D014945:Wound Healing