[Effects of composite xueliting on four gastric ulcer models in rats and mice].
Composite Xueliting (CXLT) was found to be an effective anti-ulcer agent in four experimental models in rats and mice, namely, the stress restraint-induced, histamin-induced, salicylic acid-induced and reserpine-induced ulcers. In above-mentioned models, CXLT (0.214-0.856 g/kg, 1/d x 5, per os) could inhibit gastric ulcer by 40%-63%, 48%-85%, 68%-87% and 27%-65% respectively. Among these, the salicylic acid-induced ulcer was more markedly inhibited. The result suggested that CXLT had the protective function against the gastric ulcer.
Yang
J R
JR
Dept. of Pharmacology, Wannan Medical College, Anhui.
Chen
G X
GX
Li
W M
WM
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D008297:Male; D051379:Mice; D051381:Rats; D017207:Rats, Sprague-Dawley; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control*
D000897:Anti-Ulcer Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal