title: Hypersensitivity to cefuroxime with good tolerance to other betalactams.
abstract: A 60-year-old man developed an anaphylactic reaction immediately after administration of intramuscular sodium cefuroxime. By means of oral controlled challenge, the reaction was reproduced with a smaller dose of cefuroxime axetil. Cross-reactivity with other betalactam antibiotics was ruled out by in vivo tests. This case supports once again the relevance of the side-chain in betalactam allergy.
authors.affiliation: Servicio Alergología, Hospital Xeral-Cíes, Vigo, Pontevedral, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Marcos Bravo
authors.forename: I
authors.initials: I
authors.lastname: Luna Ortiz
authors.forename: R
authors.initials: R
authors.lastname: González Vázquez
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology*; D002444:Cefuroxime / Q000009:adverse effects*; D003429:Cross Reactions; D004342:Drug Hypersensitivity / Q000209:etiology*; D004361:Drug Tolerance; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos; D016037:Single-Blind Method
chemical_list: D000900:Anti-Bacterial Agents; D010919:Placebos; D002444:Cefuroxime