Scleroderma in children.
Childhood scleroderma may present in a variety of clinical forms that differ in clinical presentation, extracutaneous features, clinical course, and outcome. All include hardening of the skin as a major feature. This article reviews these various entities, focusing on primarily the clinical features. In addition, current concepts regarding pathogenesis and treatment are discussed.
Uziel
Y
Y
Division of Rheumatology, Hospital for Sick Children, Toronto, Canada.
Miller
M L
ML
Laxer
R M
RM
D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011928:Raynaud Disease / Q000209:etiology / Q000628:therapy; D012594:Scleroderma, Localized / Q000150:complications / Q000628:therapy; D012595:Scleroderma, Systemic / Q000150:complications* / Q000628:therapy