System delay in breast cancer in whites and blacks.
Survival differences have been noted between black women and white women with breast cancer. It is hypothesized that a prolonged interval between initial medical consultation and establishment of a diagnosis (system delay), resulting in a more advanced stage of disease at diagnosis, might explain part of this survival difference. This study was performed to determine whether system delay differs between black and white breast cancer patients, and to examine predictors of delay in blacks and whites. The study population consisted of 996 female breast cancer patients from the National Cancer Institute's Black/White Cancer Survival Study, a cohort study carried out in 1985-1986 in the metropolitan areas of Atlanta, Georgia, New Orleans, Louisiana, and San Francisco/Oakland, California. The median system delay was slightly longer for blacks than for whites--2.7 weeks versus 2.1 weeks--but this difference was not statistically significant. Having a palpable lump at diagnosis was associated with reduced system delay in both races, while use of a public clinic increased system delay for blacks. Older women were less likely to be subject to longer system delay than younger women, and this effect was somewhat more pronounced in whites. Survival differences between blacks and whites are probably not due to differences in system delay. However, many women had delays of at least 3 months. Given that younger age and the absence of a palpable lump were the factors most predictive of significant system delay, interventions should be targeted specifically toward reducing system delay in younger women who present without the classical painless lump.
Caplan
L S
LS
Department of Preventive Medicine, School of Medicine, State University of New York at Stony Brook, USA.
Helzlsouer
K J
KJ
Shapiro
S
S
Freedman
L S
LS
Coates
R J
RJ
Edwards
B K
BK
D000328:Adult; D001741:Black or African American; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000208:ethnology; D015331:Cohort Studies; D005260:Female; D005845:Georgia; D006801:Humans; D008145:Louisiana; D008875:Middle Aged; D015999:Multivariate Analysis; D012017:Referral and Consultation; D012495:San Francisco; D016019:Survival Analysis; D013997:Time Factors; D044465:White People