title: T-cell activation. Two for T.
abstract: T-cell activation requires costimulation in addition to the antigen-specific signal. Recent results suggest that distinct costimulatory molecules can specifically activate different types of T-cell response.
authors.affiliation: Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
authors.forename: S
authors.initials: S
authors.lastname: Guerder
authors.forename: R A
authors.initials: RA
authors.lastname: Flavell
mesh_terms: D000818:Animals; D008213:Lymphocyte Activation; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism