title: Proteins with leucine-rich repeats.
abstract: Leucine-rich repeats are short sequence motifs present in over sixty proteins, all of which appear to be involved in protein-protein interactions. The crystal structure of ribonuclease inhibitor demonstrated that the repeats correspond to beta-alpha structural units. The recently determined crystal structure of the ribonuclease A-ribonuclease inhibitor complex suggests the basis for the protein-binding function of leucine-rich repeats.
authors.affiliation: St Vincent's Institute of Medical Research, Fitzroy, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Kobe
authors.forename: J
authors.initials: J
authors.lastname: Deisenhofer
mesh_terms: D000818:Animals; D005075:Biological Evolution; D006801:Humans; D007930:Leucine / Q000737:chemistry*; D011485:Protein Binding; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012091:Repetitive Sequences, Nucleic Acid; D017421:Sequence Analysis
chemical_list: D011506:Proteins; D007930:Leucine