Insulin-like growth factor II is focally up-regulated and functionally involved as a second signal for oncogene-induced tumorigenesis.
Naik
P
P
Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0534, USA.
Christofori
G
G
Hanahan
D
D
D000818:Animals; D017209:Apoptosis; D001483:Base Sequence; D002455:Cell Division; D017931:DNA Primers / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic; D007335:Insulin-Like Growth Factor II / Q000235:genetics* / Q000502:physiology; D007340:Insulinoma / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D051379:Mice; D008822:Mice, Transgenic; D008969:Molecular Sequence Data; D009857:Oncogenes; D010190:Pancreatic Neoplasms / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D017526:Receptor, IGF Type 1 / Q000235:genetics; D017527:Receptor, IGF Type 2 / Q000235:genetics; D015398:Signal Transduction / Q000235:genetics; D015854:Up-Regulation
D017931:DNA Primers; D012333:RNA, Messenger; D017527:Receptor, IGF Type 2; D007335:Insulin-Like Growth Factor II; D017526:Receptor, IGF Type 1