[Association of nucleotide substitutions in the cytochrome b gene and regulatory region in types of human mitochondrial DNA].
Nucleotide sequences of the cytochrome b gene fragment of the mitochondrial DNA (mtDNA) between primers b1 and b2 were determined in eleven eastern Slavs. The group analyzed consisted of samples that differed in the hypervariable segment I (HVSI) of the mtDNA control region by one to seven nucleotide substitutions. Three types of the b1-b2 segment of the cytochrome b gene were registered. A lack of correlation between diversity in the coding (cytochrome b gene) and noncoding (HVSI) regions of mtDNA was shown. Association between substitutions at positions 14905 bp in cytochrome b gene, and also 16126 bp and 16294 bp in the control region of mtDNA, was found.
Maliarchuk
B A
BA
D001483:Base Sequence; D003573:Cytochrome b Group / Q000235:genetics*; D017931:DNA Primers; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D012045:Regulatory Sequences, Nucleic Acid
D003573:Cytochrome b Group; D017931:DNA Primers; D004272:DNA, Mitochondrial
Assotsiatsiia nukleotidnykh zamen v gene tsitokhroma b i kontrol'nom regione v tipakh mitokhondrial'noĭ DNK cheloveka.