title: The evolution of vertebrate gastrulation.
abstract: The availability of molecular markers now permits the analysis of the common elements of vertebrate gastrulation. While gastrulation appears to be very diverse in the vertebrates, by analyzing a head-organizer marker, goosecoid, and a marker common to all forming mesoderm, Brachyury, we attempt to identify homologous structures and equivalent stages in Xenopus, zebrafish, chick and mouse gastrulation. Using a tail-organizer marker, Xnot-2, we also discuss how the late stages of gastrulation lead to the formation of the postanal tail, a structure characteristic of the chordates.
authors.affiliation: Department of Biological Chemistry, University of California, Los Angeles 90024-1737, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: De Robertis
authors.forename: A
authors.initials: A
authors.lastname: Fainsod
authors.forename: L K
authors.initials: LK
authors.lastname: Gont
authors.forename: H
authors.initials: H
authors.lastname: Steinbeisser
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002642:Chick Embryo; D004268:DNA-Binding Proteins / Q000235:genetics; D004627:Embryonic Induction / Q000235:genetics*; D005314:Embryonic and Fetal Development / Q000235:genetics; D005326:Fetal Proteins / Q000235:genetics; D005775:Gastrula / Q000502:physiology*; D015870:Gene Expression; D005819:Genetic Markers; D051956:Goosecoid Protein; D018398:Homeodomain Proteins; D008648:Mesoderm / Q000502:physiology; D051379:Mice; D012097:Repressor Proteins; D020825:T-Box Domain Proteins; D013623:Tail / Q000196:embryology; D014157:Transcription Factors; D014714:Vertebrates / Q000196:embryology* / Q000235:genetics; D014981:Xenopus / Q000235:genetics; D015027:Zebrafish / Q000235:genetics; D029961:Zebrafish Proteins; D000098908:Brachyury Protein
chemical_list: D004268:DNA-Binding Proteins; D005326:Fetal Proteins; D005819:Genetic Markers; D051956:Goosecoid Protein; D018398:Homeodomain Proteins; D012097:Repressor Proteins; D020825:T-Box Domain Proteins; D014157:Transcription Factors; D029961:Zebrafish Proteins; D000098908:Brachyury Protein; C497993:Gsc protein, mouse; C497995:gsc protein, zebrafish