[ACE inhibitors and early diabetic nephropathy].
At present we are able to disclose diabetic nephropathy in the very early stages, i.e. when urinary albumin excretion is only slightly increased (20-200 micrograms/min = microalbuminuria). Good blood glucose control and active antihypertensive treatment may stop or retard the further development towards renal failure. Angiotensin-converting-enzyme (ACE)-inhibitors seem to have a renoprotective effect. In this article we suggest guidelines for the use of ACE-inhibitors in patients with type 1 diabetes and early diabetic nephropathy. Special concerns are included in respect of adolescents, pregnant women and persons with type 2 diabetes.
Bangstad
H J
HJ
Barneavdelingen/Aker diabetes forskningssenter, Aker sykehus, Oslo.
Hartmann
A
A
Berg
T J
TJ
Hanssen
K F
KF
D000419:Albuminuria / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage*; D001786:Blood Glucose / Q000032:analysis; D003928:Diabetic Nephropathies / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male
D000806:Angiotensin-Converting Enzyme Inhibitors; D001786:Blood Glucose
ACE-hemmere og tidlig diabetisk nefropati.