title: Anticalculus efficacy of three dentifrices.
abstract: OBJECTIVE
  To evaluate the anticalculus effect of three commercial dentifrices.
  
  
  METHODS
  A 12-week independent and double-blind clinical study was conducted on a population of calculus-forming adult male and female subjects in Budapest, Hungary to directly compare the anticalculus efficacy of three commercially-available dentifrices, as compared to a placebo dentifrice. The three commercially-available anticalculus dentifrices compared in this clinical study to a 0.243% sodium fluoride/silica placebo dentifrice were as follows: (1) A dentifrice containing 1.3% soluble pyrophosphate and 1.5% of a PVM/MA copolymer in a 0.243% sodium fluoride/silica base. (2) A dentifrice containing 0.3% triclosan and 2% of a PVM/MA copolymer in a 0.243% sodium fluoride/silica base. (3) A dentifrice containing 0.3% triclosan and 0.75% zinc citrate in a 1.14% sodium monofluorophosphate/silica base.
  
  
  RESULTS
  All three anticalculus dentifrices provided statistically significant reductions in supragingival calculus formation, as compared to a placebo dentifrice, after 12 weeks of use. The reductions in supragingival calculus formation ranged from 39% to 55%, as compared to a placebo dentifrice, for the three commercially-available anticalculus dentifrices. There was no statistically significant difference among the three commercially-available dentifrices with regard to anticalculus efficacy.
authors.affiliation: Department of Conservative Dentistry, Semmelweis University of Medicine, Budapest, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Banoczy
authors.forename: K
authors.initials: K
authors.lastname: Sari
authors.forename: T
authors.initials: T
authors.lastname: Schiff
authors.forename: M
authors.initials: M
authors.lastname: Petrone
authors.forename: R
authors.initials: R
authors.lastname: Davies
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002951:Citrates; D019343:Citric Acid; D003728:Dental Calculus / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D011756:Diphosphates / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008298:Maleates; D008875:Middle Aged; D010710:Phosphates / Q000627:therapeutic use; D011145:Polyvinyls; D012969:Sodium Fluoride / Q000627:therapeutic use; D014260:Triclosan / Q000627:therapeutic use; D015032:Zinc
chemical_list: D002951:Citrates; D003802:Dentifrices; D011756:Diphosphates; D008298:Maleates; D010710:Phosphates; D011145:Polyvinyls; C058026:polyvinylmethoxyethylene-maleic anhydride copolymer; C012980:fluorophosphate; D019343:Citric Acid; D014260:Triclosan; D012969:Sodium Fluoride; D015032:Zinc; D005459:Fluorides