[An immunoenzyme analysis of the neurospecific proteins in the blood serum of epilepsy patients].
Serum levels of glyofibrillar acid protein (GFAP), alpha-2 glycoprotein (A2GP), alpha-1 brain globulin (A1BG), alpha-2 brain globulin (A2BG) were measured in 41 epileptic patients (2 groups--with convulsive and non-convulsive forms of the disease) with the help of "sandwich" variant of enzyme immunoassay and double-centered enzyme immunoassay on the basis of column immunosorption chromatography. Investigations were performed in the interval from the first to the 30th day after the fit. The level of at least one of neurospecific proteins was elevated in 65.2% of patients. The same changes were revealed in one third of patients during the period of 30 days. Frequency discovering of A1BG as compared to A2GP was significantly lower only in patients with convulsive epilepsy. It allowed the authors to suggest, that serum antigenic levels in patients with various forms of epilepsy were different.
Asanova
L M
LM
Chekhonin
V P
VP
Gavrilenko
A Ia
AIa
D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000097:blood*; D005260:Female; D005916:Globulins / Q000032:analysis; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D009419:Nerve Tissue Proteins / Q000097:blood*
D001798:Blood Proteins; D005916:Globulins; D006023:Glycoproteins; D009419:Nerve Tissue Proteins
Immunofermentnyĭ analiz neĭrospetsificheskikh belkov v syvorotke krovi bol'nykh épilepsieĭ.