title: Silicone gel sheeting for the prevention and management of evolving hypertrophic and keloid scars.
abstract: BACKGROUND
  Hypertrophic scars and keloids remain a problem for surgeons. Topical and intralesional corticosteroids, positive pressure dressings, cryotherapy, and laser therapy are helpful but not uniformly successful.
  
  
  OBJECTIVE
  To document the effectiveness of silicone gel sheeting in the prevention and/or reduction of evolving hypertrophic scars and keloids.
  
  
  METHODS
  Silicone gel sheeting was placed over evolving scars in 20 cases. The dressing was worn for at least 12 hours a day. Biopsies were examined for the presence of silica in the tissue.
  
  
  RESULTS
  Lesions improved during the treatment period in 85% of the cases. The mechanisms of action are unknown. Positive pressure was not necessary. No silica from the dressing was found at the wound site.
  
  
  CONCLUSIONS
  Daily treatments with silicone gel sheeting should begin as soon as an itchy red streak develops in a maturing wound. The dressing is effective in reducing the bulk of these lesions.
authors.affiliation: Institute for Skin Research, Newport Beach, California 92660, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Fulton
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001458:Bandages / Q000009:adverse effects; D001707:Biopsy, Needle; D017439:Cicatrix, Hypertrophic / Q000473:pathology / Q000517:prevention & control* / Q000628:therapy; D005069:Evaluation Studies as Topic; D005260:Female; D005782:Gels; D006801:Humans; D007627:Keloid / Q000473:pathology / Q000517:prevention & control* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012822:Silicon Dioxide / Q000032:analysis; D012826:Silicone Elastomers / Q000009:adverse effects / Q000627:therapeutic use*; D012867:Skin / Q000737:chemistry / Q000473:pathology; D013997:Time Factors
chemical_list: D005782:Gels; D012826:Silicone Elastomers; D012822:Silicon Dioxide