title: Acute Wernicke's encephalopathy associated with hyperemesis gravidarum: magnetic resonance imaging findings.
abstract: A 25-year-old woman with hyperemesis gravidarum developed acute Wernicke's encephalopathy during prolonged intravenous fluid therapy without vitamin supplements. Delay in diagnosis led to a persistent severe neurological deficit, including coma. Gadolinium-diethylenetriaminepentaacetic acid-enhanced magnetic resonance imaging revealed symmetrical lesions around the aqueduct and fourth ventricle, which resolved after treatment with thiamine. She did not regain consciousness. This report demonstrates the diagnostic value of enhanced magnetic resonance imaging in acute Wernicke's encephalopathy.
authors.affiliation: Department of Medicine, King Khalid National Guard Hospital, Jeddah, Saudi Arabia.
authors.forename: S M
authors.initials: SM
authors.lastname: Omer
authors.forename: M Z
authors.initials: MZ
authors.lastname: al Kawi
authors.forename: J
authors.initials: J
authors.lastname: al Watban
authors.forename: S
authors.initials: S
authors.lastname: Bohlega
authors.forename: D R
authors.initials: DR
authors.lastname: McLean
authors.forename: G
authors.initials: G
authors.lastname: Miller
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D003287:Contrast Media; D005260:Female; D005440:Fluid Therapy; D019786:Gadolinium DTPA; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications* / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011247:Pregnancy; D014899:Wernicke Encephalopathy / Q000175:diagnosis / Q000209:etiology*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA