The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin.
Dameron
K M
KM
Department of Microbiology-Immunology, Northwestern University, Chicago, Illinois 60611, USA.
Volpert
O V
OV
Tainsky
M A
MA
Bouck
N
N
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D016158:Genes, p53; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000235:genetics / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000096:biosynthesis* / Q000235:genetics; D008954:Models, Biological; D009154:Mutation; D009389:Neovascularization, Pathologic / Q000235:genetics* / Q000378:metabolism*; D010641:Phenotype; D051381:Rats; D019699:Thrombospondins; D014162:Transfection; D016159:Tumor Suppressor Protein p53 / Q000235:genetics
D008562:Membrane Glycoproteins; D019699:Thrombospondins; D016159:Tumor Suppressor Protein p53