[Effect of single dose administration of nitrendipine on pulmonary arterial pressure measured using doppler echocardiography].
The effect of a single oral dose of Nitrendipine (20 mg) on mean pulmonary arterial pressure was studied in 14 patients with COPD and chronic cor pulmonale and 12 patients with COPD and without coexistent cor pulmonale. Parameters were assessed with Doppler echocardiography calculating average acceleration time of blood from the pulmonary artery. Simultaneously arterial pressure and heart rate were determined. The authors found that a single oral dose (20 mg) of Nitrendipine significantly lowered elevated pressure in the pulmonary artery during at least 6 hours without effecting heart rate.
Bujak
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Pracowni Echokardiografii ZOZ w Debicy.
Kozik
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D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D015150:Echocardiography, Doppler; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D008173:Lung Diseases, Obstructive / Q000150:complications; D008297:Male; D008875:Middle Aged; D009568:Nitrendipine / Q000494:pharmacology*; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000502:physiology; D011660:Pulmonary Heart Disease / Q000150:complications
D002121:Calcium Channel Blockers; D009568:Nitrendipine
Wpływ jednorazowej dawki nitrendypiny na ciśnienie płucne mierzone metoda echokardiografii dopplerowskiej.