Reliability of salivary testosterone measurements: a multicenter evaluation.
The reliability of salivary testosterone assays was evaluated by nine laboratories in four countries. Each laboratory used its own RIA procedures to assay samples from a set of 100 male and 100 female subjects. Agreement among the laboratories on mean scores was within the range reported by Read (Ann N Y Acad Sci 1993; 694: 161-76). Overall agreement on individual scores, as indicated by the intraclass correlation coefficient computed within subjects across laboratories, was r = 0.87 for men and r = 0.78 for women. Mean agreement between each laboratory and the combined set of all other laboratories (via Fisher's Z-transformation) was r = 0.61 for men and r = 0.58 for women. We take these latter values to be the best estimates of the average reliability of laboratories in their ordering of individual samples.
Dabbs
J M
JM
Department of Psychology, Georgia State University, Atlanta, USA.
Campbell
B C
BC
Gladue
B A
BA
Midgley
A R
AR
Navarro
M A
MA
Read
G F
GF
Susman
E J
EJ
Swinkels
L M
LM
Worthman
C M
CM
D005260:Female; D006801:Humans; D007753:Laboratories / Q000706:statistics & numerical data; D008297:Male; D011863:Radioimmunoassay / Q000706:statistics & numerical data*; D012016:Reference Values; D012463:Saliva / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012727:Sex Characteristics; D013739:Testosterone / Q000032:analysis*
D013739:Testosterone