[Scintigraphy of the parathyroid glands with 99mTc-MIBI].
OBJECTIVE
Since about 3 years 99mTc-MIBI is used instead of 201Tl/99mTc subtraction scintigraphy for the localization of parathyroid involvement in hyperparathyroidism (HPT). The sensitivity of the new method was evaluated.


METHODS
24 patients aged between 28 and 83 years with surgically confirmed primary HPT were studied. Planar images were acquired 15 minutes and 3 hours after tracer injection. Additionally, in 9 patients dynamic images were obtained for 2 hours to study tracer kinetics.


RESULTS
19 out of 24 adenomas (79%) were identified correctly with 99mTc-MIBI.


CONCLUSIONS
The sensitivity of the scintigraphy using 99mTc-MIBI is in the range of the 201Tl/99mTc subtraction scintigraphy. Because of the superior logistic and the lower radiation exposure, 99mTc-MIBI can replace the 201Tl/99mTc scintigraphy in the preoperative diagnostic assessment.
Grünwald
F
F
Klinik und Poliklinik für Nuklearmedizin, Universität Bonn.
Späth
G
G
Menzel
C
C
Pavics
L
L
Sudhop
T
T
Liesegang
P
P
Klingmüller
D
D
Schomburg
A
A
Biersack
H J
HJ
D000236:Adenoma / Q000000981:diagnostic imaging* / Q000601:surgery*; D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D016105:Parathyroidectomy; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
D003287:Contrast Media; D017256:Technetium Tc 99m Sestamibi
Nebenschilddrüsenszintigraphie mit 99mTc-MIBI.