[Peutz-Jeghers syndrome and adenocarcinoma. Report of a case].
Peutz-Jeghers syndrome is a rare disease, characterized by autosomic inheritance, presenting skin stain and hamartomatous polyps. We report one case of Peutz-Jeghers syndrome and duodenal adenocarcinoma in a young male who presented with liver metastasis and pancreatic invasion. Such association is reported to be presented in 5% of patients with the syndrome. The reasons of such association are unknown, being possible that: 1) there is malignant degeneration of a adenomatous polyp; 2) malignant degeneration of a hamartomatous polyp, or 3) adenomatous portion of a hamartomatous polyp could undergo malignant transformation.
Castro
R R
RR
Enfermaria de Gastroenterologia, Hospital São Paulo.
Brant
C Q
CQ
Ferreira
L E
LE
Geocze
S
S
Ferrari Júnior
A P
AP
Lanzoni
V P
VP
Forones
N M
NM
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D004379:Duodenal Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications* / Q000473:pathology
Síndrome de Peutz-Jeghers e adenocarcinoma. Relato de caso.