title: Physical map and organization of Arabidopsis thaliana chromosome 4.
abstract: A physical map of Arabidopsis thaliana chromosome 4 was constructed in yeast artificial chromosome clones and used to analyze the organization of the chromosome. Mapping of the nucleolar organizing region and the centromere integrated the physical and cytogenetic maps. Detailed comparison of physical with genetic distances showed that the frequency of recombination varied substantially, with relative hot and cold spots occurring along the whole chromosome. Eight repeated DNA sequence families were found in a complex arrangement across the centromeric region and nowhere else on the chromosome.
authors.affiliation: Department of Molecular Genetics, Biotechnology, John Innes Centre, Colney, Norwich, UK.
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: J
authors.initials: J
authors.lastname: West
authors.forename: K
authors.initials: K
authors.lastname: Love
authors.forename: Z
authors.initials: Z
authors.lastname: Lenehan
authors.forename: C
authors.initials: C
authors.lastname: Lister
authors.forename: H
authors.initials: H
authors.lastname: Thompson
authors.forename: D
authors.initials: D
authors.lastname: Bouchez
authors.forename: C
authors.initials: C
authors.lastname: Dean
mesh_terms: D017360:Arabidopsis / Q000235:genetics*; D002503:Centromere / Q000235:genetics; D002874:Chromosome Mapping; D016386:Chromosome Walking; D002875:Chromosomes / Q000235:genetics*; D018244:Chromosomes, Artificial, Yeast; D018744:DNA, Plant / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D017343:Genes, Plant; D005819:Genetic Markers; D018745:Genome, Plant; D009693:Nucleic Acid Hybridization; D009697:Nucleolus Organizer Region / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D018744:DNA, Plant; D004275:DNA, Ribosomal; D005819:Genetic Markers