title: [Use of different regimes of etiopathogenetic therapy in pulmonary tuberculosis in adolescents].
abstract: Clinical parameters were assessed in 178 adolescents aged 15-17 with pulmonary tuberculosis. Half of them exhibited changes in the blood picture, immunological E-RFC suppression, enhanced lipid peroxidation. The above disturbances and x-ray evidence served the basis for differential approach to administration of etiotropic treatment. 35 patients received prednisolone in combined therapy. 42, 25 and 51 patients were given olifen, sodium thiosulfate and tuberculin, respectively. 25 patients underwent plasmapheresis. Oriented use of etiopathogenetic therapy raised the efficacy of treatment. Clinical effects went in parallel with cellular response normalization and lipid peroxidation.
authors.forename: M V
authors.initials: MV
authors.lastname: Pavlova
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000975:Antioxidants / Q000008:administration & dosage; D000995:Antitubercular Agents / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008297:Male; D010647:Phenyl Ethers / Q000008:administration & dosage; D010956:Plasmapheresis; D011239:Prednisolone / Q000008:administration & dosage; D013885:Thiosulfates / Q000008:administration & dosage; D014373:Tuberculin / Q000008:administration & dosage; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000975:Antioxidants; D000995:Antitubercular Agents; D005938:Glucocorticoids; D010647:Phenyl Ethers; D013885:Thiosulfates; D014373:Tuberculin; C085806:olifen; D011239:Prednisolone; C017717:sodium thiosulfate
vernacular_title: Primenenie differentsirovannykh rezhimov étiopatogeneticheskoĭ terapii pri tuberkuleze legkikh u podrostkov.