[Immunological and nonspecific reactivity in patients with infiltrative pulmonary tuberculosis associated with chronic nonspecific lung diseases].
When examined for immunological status, complement, basic endogenic protease blockers parameters, patients with infiltrative destructive tuberculosis of the lungs (IDTL) and IDTL combination with exacerbation of chronic pyo-inflammatory bronchitis, exhibited disturbances in cellular and humoral immunity, complement activity, content of alpha 1 protease inhibitor and alpha 2 macroglobulin which aggravated in combined respiratory pathology. Nonspecific aerosol treatment with native protease inhibitors (contrykal or gordox) and thymalin aroused the efficacy of etiotropic treatment and promoted normalization of the above defense systems.
Morozova
T I
TI
Khudzik
L B
LB
Rebrov
A P
AP
D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000328:Adult; D000336:Aerosols; D007611:Aprotinin / Q000008:administration & dosage; D001402:B-Lymphocytes / Q000276:immunology; D001991:Bronchitis / Q000150:complications / Q000276:immunology; D002908:Chronic Disease; D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D011480:Protease Inhibitors / Q000008:administration & dosage; D013601:T-Lymphocytes / Q000276:immunology; D013951:Thymus Hormones / Q000008:administration & dosage; D014361:Trypsin Inhibitors / Q000008:administration & dosage; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000336:Aerosols; D007136:Immunoglobulins; D011480:Protease Inhibitors; D013951:Thymus Hormones; D014361:Trypsin Inhibitors; C011475:gordox; C032805:thymalin; D003165:Complement System Proteins; D007611:Aprotinin
Immunologicheskaia i nespetsificheskaia reaktivnost' u bol'nykh infil'trativnym tuberkulezom legkikh v sochetanii s khronicheskimi nespetsificheskimi zabolevaniiami legkikh.