title: Lipoprotein concentrations in normolipidemic males consuming oleic acid-rich diets from two different sources: olive oil and oleic acid-rich sunflower oil.
abstract: The effects on plasma lipid concentrations of two oleic acid-rich diets, prepared with two different plant oils--olive oil and sunflower oil high in monounsaturated fatty acids (MUFAs)-- were compared with a National Cholesterol Education Program (NCEP) I diet. Twenty-one healthy, normolipidemic, young males consumed an NCEP-I diet (30% of energy as fat) during a 25-d period. Subjects were then assigned to two 4-wk study periods, according to a randomized, crossover design. Group one was placed on an olive oil-enriched diet (40% fat, 22% MUFAs), followed by a 4-wk period of a sunflower oil-enriched diet (40% fat, 22% MUFAs). In group two, the order of the diets was reversed. Both MUFA dietary periods resulted in an increase in high-density-lipoprotein (HDL) cholesterol (7% for the olive oil diet and 4% for the sunflower oil diet) and in apolipoprotein (apo) A-I (9% for both) compared with the NCEP-I diet. Low-density-lipoprotein (LDL) cholesterol and apo B concentrations (x +/- SEM) were lower (P < 0.05) during the sunflower oil diet (2.40 +/- 0.11 mmol/L, 0.85 +/- 0.04 mg/L) than during the olive oil diet (2.64 +/- 0.15 mmol/L, 0.93 +/- 0.05 mg/L). No significant differences were observed in these variables between the sunflower oil and NCEP-I (2.48 +/- 0.13 mmol/L, 0.89 +/- 0.04 mg/L) diets.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Lipid Research Unit, University Hospital Reina Sofia, University of Cordoba Medical School, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Perez-Jimenez
authors.forename: A
authors.initials: A
authors.lastname: Espino
authors.forename: F
authors.initials: F
authors.lastname: Lopez-Segura
authors.forename: J
authors.initials: J
authors.lastname: Blanco
authors.forename: V
authors.initials: V
authors.lastname: Ruiz-Gutierrez
authors.forename: J L
authors.initials: JL
authors.lastname: Prada
authors.forename: J
authors.initials: J
authors.lastname: Lopez-Miranda
authors.forename: J
authors.initials: J
authors.lastname: Jimenez-Pereperez
authors.forename: J M
authors.initials: JM
authors.lastname: Ordovas
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood; D018592:Cross-Over Studies; D004041:Dietary Fats / Q000008:administration & dosage*; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D009829:Oleic Acids / Q000008:administration & dosage* / Q000494:pharmacology; D000069463:Olive Oil; D010938:Plant Oils; D000074242:Sunflower Oil
chemical_list: D004041:Dietary Fats; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; D008055:Lipids; D008074:Lipoproteins; D009829:Oleic Acids; D000069463:Olive Oil; D010938:Plant Oils; D000074242:Sunflower Oil; D002784:Cholesterol