title: [Non-sedative antihistaminics in the treatment of chronic urticaria].
abstract: Antihistamines are the drugs of choice in the symptomatic relief of chronic idiopathic urticaria; however, the usefulness of classic antihistamines has been limited by side effects. In the 1980s a new class of antihistamines has been developed that maintains effectiveness and produces less side effects (eg anticholinergic side effects, daytime sedation, etc). This review analyzes each of the new nonsedating antihistamines commercially available in Spain (astemizole, ebastine, cetirizine, loratadine and terfenadine) and evaluates its clinical efficacy and safety in the treatment of chronic idiopathic urticaria.
authors.forename: J M
authors.initials: JM
authors.lastname: Negro
authors.forename: F
authors.initials: F
authors.lastname: Sarrió
authors.forename: J C
authors.initials: JC
authors.lastname: Miralles
authors.forename: F J
authors.initials: FJ
authors.lastname: García Sellés
authors.forename: J D
authors.initials: JD
authors.lastname: López Sánchez
authors.forename: J a
authors.initials: Ja
authors.lastname: Pagán
authors.forename: J
authors.initials: J
authors.lastname: Hernándéz
mesh_terms: D002908:Chronic Disease; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D014581:Urticaria / Q000188:drug therapy*
chemical_list: D006634:Histamine H1 Antagonists
vernacular_title: Los antihistamínicos no sedantes en el tratamiento de la urticaria crónica.