title: Experimental studies on human bronchial smooth muscle in vitro.
abstract: The aim of this study was the investigation of bronchial reactivity in human bronchial smooth muscle in vitro. In fact, the study has two purposes: to achieve the best methods of research on human bronchial strips reactivity in vitro; to reveal the effect of acetylcholine and histamine on bronchial smooth muscle; The contractile effect of acetylcholine appears at 10(-6) M in the organ-bath; the maximal acetylcholine contraction was obtained at 10(-3) M in the organ-bath. Histamine induced a maximal contraction at 10(-3) M, but a concentration of 10(-3) M in the organ bath had no effect.
authors.affiliation: Department of Physiology, University of Medicine and Pharmacy, Timişoara, Romania.
authors.forename: G
authors.initials: G
authors.lastname: Mihalas
authors.forename: A
authors.initials: A
authors.lastname: Petroiu
authors.forename: I
authors.initials: I
authors.lastname: Siska
authors.forename: G
authors.initials: G
authors.lastname: Tanasie
authors.forename: C
authors.initials: C
authors.lastname: Mederle
authors.forename: C
authors.initials: C
authors.lastname: Bunu
authors.forename: F
authors.initials: F
authors.lastname: Schneider
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000368:Aged; D001980:Bronchi / Q000187:drug effects / Q000502:physiology*; D016084:Bronchoconstriction / Q000502:physiology; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D009994:Osmolar Concentration
chemical_list: D006632:Histamine; D000109:Acetylcholine