[Mixed IgM kappa-IgM lambda cryoglobulinemia with a double monoclonal serum component. A case report].
The paper describes a case of mixed cryoglobulinemia with a double serum monoclonal component. The serum immunofixation revealed that a monoclonal component was IgG lambda while the other was positive for antisera anti-IgM, anti-k and anti-lambda even if the EP proved monoclonal. Resuspended cryoglobulins had the same electrophoresis pattern and the same reactivity for the antisera as the IgM serum component.
Napoli
P
P
Dipartimento di Medicina, Ospedale Molinette, Università degli Studi, Torino.
Battaglio
S
S
Ciaiolo
C
C
Boccadoro
M
M
D000888:Antibodies, Anti-Idiotypic / Q000097:blood; D000911:Antibodies, Monoclonal / Q000097:blood*; D003449:Cryoglobulinemia / Q000276:immunology*; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D007146:Immunoglobulin lambda-Chains / Q000097:blood*; D008297:Male
D000888:Antibodies, Anti-Idiotypic; D000911:Antibodies, Monoclonal; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains
Crioglobulinemia mista IgM cappa-IgM lambda con doppia componente monoclonale sierica. Descrizione di un caso.