[Significance of heparin elimination from plasma in the assessment of coagulogram and antithrombin III activity].
An original adsorbent for non-fractionated and low-molecular weight heparin (fraxiparin,Sanofi) has been developed and tried in experiments and in a clinical setting. Tests carried out in 58 patients with disseminated intravascular coagulation and thromboses treated with heparin demonstrated the possibility of obtaining objective data on the status of the blood clotting system. Heparin adsorption is particularly important in measurements of heparin III activity, for even low concentrations of heparin mask the defect of this anticoagulant.
Momot
A P
AP
Sokolov
E A
EA
Tseĭmakh
I Ia
IIa
D000327:Adsorption; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D000990:Antithrombin III / Q000032:analysis*; D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy*; D005260:Female; D006493:Heparin / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017762:Nadroparin / Q000627:therapeutic use*
D000925:Anticoagulants; D017762:Nadroparin; D000990:Antithrombin III; D006493:Heparin
Znachenie éliminatsii iz plazmy geparina dlia otsenki koagulogrammy i aktivnosti antitrombina III.