Comparison of TCAs and SSRIs in the treatment of major depression in hospitalized geriatric patients.
This study compares a cohort of hospitalized geriatric patients with major depression, treated with tricyclic anti-depressants (TCAs), with a cohort of patients treated with selective serotonin reuptake inhibitors (SSRIs). The groups were compared on demographic, treatment, and outcome variables. Demographically, the groups were similar and did not differ on measures of outcome or risk for side effects. We conclude that SSRIs are equal to TCAs in the treatment of major depression in hospitalized geriatric patients.
Miller
F T
FT
Cornell University Medical College, New York, NY 10021, USA.
Freilicher
J
J
D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology / Q000534:rehabilitation*; D003891:Desipramine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000627:therapeutic use*; D006331:Heart Diseases / Q000139:chemically induced; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008297:Male; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*
D000929:Antidepressive Agents, Tricyclic; D003891:Desipramine; D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors