title: Cerebral magnetic resonance imaging compared in Alzheimer's and multi-infarct dementia.
abstract: Cerebral magnetic resonance images (MRI) were compared between two groups, each of 25 patients, one with senile dementia of the Alzheimer's type (SDAT) and the other with multi-infarct dementia (MID). MRI proved to be clinically useful for differentiating SDAT from MID, utilizing a multivariate model of six MRI criteria as follows: ventricular-brain ratio, presence of subcortical infarcts, bifrontal ventricular ratio, bicaudate ventricular ratio, third ventricular ratio, and presence of diffuse periventricular high-intensity white matter lucencies. Utilizing all six MRI criteria, classification by discriminant function analysis provided 84% correct diagnostic agreement with clinical classification of MID patients, 92% for SDAT patients, and 88% for the total cohort of demented patients.
authors.affiliation: Cerebral Blood Flow Laboratories, Veterans Administration Medical Center, Houston, TX 77211, USA.
authors.forename: K M
authors.initials: KM
authors.lastname: Reed
authors.forename: R L
authors.initials: RL
authors.lastname: Rogers
authors.forename: J S
authors.initials: JS
authors.lastname: Meyer
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D015161:Dementia, Multi-Infarct / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged