title: Application of antibody titers against bovine viral diarrhea virus (BVDV) as a measure to detect herds with cattle persistently infected with BVDV.
abstract: Based on the distribution of antibody titers against bovine viral diarrhea virus (BVDV) in 10 Michigan dairy herds, it was calculated that screening of 5 young stock for BVDV antibody titer could be used to distinguish herds with persistently infected (PI) animals from herds without such animals. The herds were selected to represent 3 different herd categories: A, herds without use of vaccination and without PI animals (5 herds); B, herds with use of killed vaccine but no PI animals (2 herds); C, herds with use of killed vaccine and presence of PI animals (3 herds). The animals were described as having high antibody titers (> or = 128) or low antibody titers (< or = 64). For animals from 9 to 18 months of age, the probability of obtaining at least 3 animals with high titers among a screening sample of 5 animals was calculated as < 0.001 for all herds in category A, < 0.01 for the 2 herds in category B, and > 0.99 for all herds in category C. Thus, among herds in this study, by categorizing 9-18-month-old animals as having high titers (> or = 128) or low titers (< or = 64), herds with PI cattle could be distinguished from other herds by testing only 5 animals.
authors.affiliation: Department of Clinical Studies, The Royal Veterinary and Agricultural University, Frederikberg, Denmark.
authors.forename: H
authors.initials: H
authors.lastname: Houe
authors.forename: J C
authors.initials: JC
authors.lastname: Baker
authors.forename: R K
authors.initials: RK
authors.lastname: Maes
authors.forename: P L
authors.initials: PL
authors.lastname: Ruegg
authors.forename: J W
authors.initials: JW
authors.lastname: Lloyd
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D000917:Antibody Formation; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000453:epidemiology* / Q000276:immunology* / Q000517:prevention & control; D002417:Cattle; D005260:Female; D008824:Michigan; D010576:Pestivirus / Q000276:immunology*; D011336:Probability; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
chemical_list: D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines