Methylphenidate in the treatment of neurobehavioral slowing associated with cancer and cancer treatment.
Psychostimulants used in the treatment of psychiatric conditions, including depression, alleviate some of the observed psychomotor retardation. We describe 3 patients with impairments of arousal and psychomotor speed secondary to tumor-related organic brain dysfunction who benefited from stimulant therapy.
Weitzner
M A
MA
Department of Neuro-Oncology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
Meyers
C A
CA
Valentine
A D
AD
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001143:Arousal / Q000187:drug effects; D001254:Astrocytoma / Q000150:complications / Q000628:therapy; D001288:Attention / Q000187:drug effects; D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology / Q000628:therapy; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D005260:Female; D005909:Glioblastoma / Q000150:complications / Q000628:therapy; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000209:etiology* / Q000523:psychology; D008774:Methylphenidate / Q000627:therapeutic use*; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011878:Radiotherapy / Q000009:adverse effects*
D000970:Antineoplastic Agents; D000697:Central Nervous System Stimulants; D008774:Methylphenidate