title: The role of carbon dioxide and atmospheric air in double-contrast barium enema.
abstract: BACKGROUND
  Patient discomfort 0-24 h after double-contrast barium enema (DCBE) was investigated in two ways.
  
  
  METHODS
  In part 1, 139 patients, not previously informed, were contacted by telephone to assess symptom rates without bias. In part 2, designed as a prospective randomized double-blind trial, the effect of carbon dioxide (CO2) as an insufflating gas was compared with conventional atmospheric air (AA).
  
  
  RESULTS
  Part 1: 10% experienced severe abdominal pain, and 18% severe abdominal distention. Part 2: Low discomfort rates were found for both severe pain (7% for AA vs. 2% for CO2) and severe distention (13% for AA vs. 8% for CO2); the differences were not significant. In both parts of the study, female patients with a history of abdominal discomfort of "colon irritable" type were significantly overrepresented in the severely symptomatic groups. Equal numbers of patients experiencing severe abdominal distention for the first time were found in both the AA and CO2 groups, ruling out AA as the sole cause of these symptoms.
  
  
  CONCLUSIONS
  Abdominal post-DCBE discomfort seems to be less frequent than previously reported and is not effectively eliminated by CO2. We still find the use of AA in DCBEs justified.
authors.affiliation: Department of Radiology and Ultrasound, Gentofte Amtssygehus, University of Copenhagen, Hellerup, Denmark.
authors.forename: N
authors.initials: N
authors.lastname: Skovgaard
authors.forename: C
authors.initials: C
authors.lastname: Sloth
authors.forename: E
authors.initials: E
authors.lastname: von Benzon
authors.forename: G S
authors.initials: GS
authors.lastname: Jensen
mesh_terms: D015746:Abdominal Pain / Q000453:epidemiology* / Q000209:etiology; D000368:Aged; D001466:Barium Sulfate; D002245:Carbon Dioxide; D004311:Double-Blind Method; D004733:Enema / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011029:Pneumoradiography / Q000009:adverse effects*; D011446:Prospective Studies; D017678:Sex Distribution
chemical_list: D002245:Carbon Dioxide; D001466:Barium Sulfate