title: The prostate involvement as prognostic factor in patients with superficial bladder tumors.
abstract: OBJECTIVE
  The prognostic value of prostate involvement in patients with superficial bladder cancer was analyzed.
  
  
  METHODS
  We studied 96 patients with prostate involvement. Taking progression-free survival rate as an end point, univariate and multivariate analyses were done.
  
  
  RESULTS
  The presence or absence of bladder carcinoma in situ is related to poor and good prognoses, respectively (p < 0.001). Stromal invasion (p < 0.001) and pan-urothelial involvement (p = 0.03) were also identified as independent factors of poor prognosis.
  
  
  CONCLUSIONS
  Patients with tumor limited to the mucosa can be treated conservatively. Cystoprostatectomy can be performed in patients with ductal involvement. The prognosis of patients with stromal invasion is poor despite radical treatment.
authors.affiliation: Department of Urology, Instituto Valenciano de Oncologia, Valencia, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Solsona
authors.forename: I
authors.initials: I
authors.lastname: Iborra
authors.forename: J V
authors.initials: JV
authors.lastname: Ricós
authors.forename: J L
authors.initials: JL
authors.lastname: Monrós
authors.forename: J L
authors.initials: JL
authors.lastname: Casanova
authors.forename: S
authors.initials: S
authors.lastname: Almenar
mesh_terms: D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000556:secondary* / Q000628:therapy; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000556:secondary* / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy