In vivo chondrogenesis in collagen sponge sandwiched by perichondrium.
In order to increase the cartilage synthesis of the perichondrium, we combined auricular perichondrium with a collagen sponge as a template (perichondrium-sandwiched collagen sponge) and implanted the assembly as an autograft into the back of rabbits. Microscopic examination revealed that cartilaginous tissue was produced in the collagen sponge and chondrosynthesis was accelerated in the collagen sponge implants in comparison with that in materials containing perichondrium alone.
Matsuda
K
K
Department of Plastic Surgery, Kyoto University, Japan.
Nagasawa
N
N
Suzuki
S
S
Isshiki
N
N
Ikada
Y
Y
D000818:Animals; D001672:Biocompatible Materials; D002356:Cartilage / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D003094:Collagen; D004431:Ear, External; D016062:Porosity; D019736:Prostheses and Implants / Q000592:standards*; D011817:Rabbits; D015503:Surgical Sponges / Q000592:standards*; D013698:Templates, Genetic
D001672:Biocompatible Materials; D003094:Collagen