title: [Peutz-Jeghers syndrome and adenocarcinoma. Report of a case].
abstract: Peutz-Jeghers syndrome is a rare disease, characterized by autosomic inheritance, presenting skin stain and hamartomatous polyps. We report one case of Peutz-Jeghers syndrome and duodenal adenocarcinoma in a young male who presented with liver metastasis and pancreatic invasion. Such association is reported to be presented in 5% of patients with the syndrome. The reasons of such association are unknown, being possible that: 1) there is malignant degeneration of a adenomatous polyp; 2) malignant degeneration of a hamartomatous polyp, or 3) adenomatous portion of a hamartomatous polyp could undergo malignant transformation.
authors.affiliation: Enfermaria de Gastroenterologia, Hospital São Paulo.
authors.forename: R R
authors.initials: RR
authors.lastname: Castro
authors.forename: C Q
authors.initials: CQ
authors.lastname: Brant
authors.forename: L E
authors.initials: LE
authors.lastname: Ferreira
authors.forename: S
authors.initials: S
authors.lastname: Geocze
authors.forename: A P
authors.initials: AP
authors.lastname: Ferrari Júnior
authors.forename: V P
authors.initials: VP
authors.lastname: Lanzoni
authors.forename: N M
authors.initials: NM
authors.lastname: Forones
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D004379:Duodenal Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications* / Q000473:pathology
vernacular_title: Síndrome de Peutz-Jeghers e adenocarcinoma. Relato de caso.