Reversal of atropine-resistant atrioventricular block with intravenous aminophylline in the early phase of inferior wall acute myocardial infarction following treatment with streptokinase.
We report three patients with acute inferior myocardial infarction treated with aspirin (150 mg) and streptokinase (1.5 MU over 60 min), who developed atropine-resistant bradyarrhythmias during or immediately following streptokinase. The bradyarrhythmias responded to aminophylline, thus avoiding the need for temporary pacing.
Goodfellow
J
J
Department of Cardiology, Southmead Hospital, Bristol, U.K.
Walker
P R
PR
D000368:Aged; D000628:Aminophylline / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use*; D004351:Drug Resistance; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use
D000628:Aminophylline; D001285:Atropine; D013300:Streptokinase