Transverse myelopathy complicating mixed connective tissue disease.
We report the case of a 46-year-old female patient with transverse myelitis complicating mixed connective tissue disease (MCTD). She responded well to steroid and immunosuppressive therapy. Unlike in systemic lupus erythematosus (SLE), transverse myelopathy in association with MCTD is very rarely described. The mechanisms, diagnosis and treatment of transverse myelitis in MCTD are briefly discussed.
Mok
C C
CC
University Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong.
Lau
C S
CS
D001379:Azathioprine / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008875:Middle Aged; D008947:Mixed Connective Tissue Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D009188:Myelitis, Transverse / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D009460:Neurologic Examination / Q000187:drug effects; D011241:Prednisone / Q000008:administration & dosage; D013116:Spinal Cord / Q000187:drug effects / Q000503:physiopathology
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D001379:Azathioprine; D011241:Prednisone