Enzyme structures. DNA repair flips out.
New insights into the workings of the repair enzymes that police the genome for damage to DNA come from the recently determined structures of two uracil-DNA glycosylases.
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Department of Molecular and Cellular Toxicology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
D045647:DNA Glycosylases; D004260:DNA Repair; D006801:Humans; D009699:N-Glycosyl Hydrolases / Q000378:metabolism*; D011487:Protein Conformation; D014498:Uracil / Q000378:metabolism; D051981:Uracil-DNA Glycosidase; D014764:Viral Proteins / Q000378:metabolism
D014764:Viral Proteins; D014498:Uracil; D045647:DNA Glycosylases; D009699:N-Glycosyl Hydrolases; D051981:Uracil-DNA Glycosidase