title: Hydrocephalus in Guillain-Barré syndrome.
abstract: Hydrocephalus and pseudotumour cerebri are a rare complication of Guillain-Barré syndrome (GBS), occurring in about 4% of the cases. The high concentration of cerebrospinal fluid (CSF) protein may lead to a decreased CSF absorption in arachnoid villi. A 10-year-old boy with GBS and hydrocephalus is presented. A mechanical ventilation was required 7 days after admission and he had been on the mechanical ventilation for 6 weeks. Lumbar puncture performed on admission revealed clear CSF with an opening pressure of 15 cm H2O and no cells, a normal glucose level and a protein of 240 mg/dl. He complained of headache and diplopia 11 weeks after admission. Fundoscopy revealed papilloedema, and bilateral mild abducens pareses were also detected. Magnetic resonance imaging displayed a communicating hydrocephalus and interstitial oedema. A ventriculo-peritoneal shunt relieved the symptoms of intracranial hypertension. In GBS, serial computed tomographic scans should be performed in patients with headache and papilloedema. Hydrocephalus may develop in GBS.
authors.affiliation: Department of Neurosurgery, Ege University Faculty of Medicine, Izmir, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Erşahin
authors.forename: S
authors.initials: S
authors.lastname: Mutluer
authors.forename: T
authors.initials: T
authors.lastname: Yurtseven
mesh_terms: D002556:Cerebrospinal Fluid Proteins / Q000134:cerebrospinal fluid; D002648:Child; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D010211:Papilledema / Q000175:diagnosis / Q000601:surgery; D011129:Polyradiculoneuropathy / Q000175:diagnosis* / Q000601:surgery; D011559:Pseudotumor Cerebri / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt
chemical_list: D002556:Cerebrospinal Fluid Proteins