Helicobacter pylori and gastric neoplasia: evolving concepts.
There is evidence that Helicobacter pylori infection is associated with gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma and possibly with non-ulcer dyspepsia. Eradication therapy for confirmed H. pylori infection may therefore become mandatory in patients with non-ulcer dyspepsia severe enough to warrant endoscopy and in first-degree relatives of patients with gastric cancer. However, routine treatment of asymptomatic carriers awaits confirmation of the association with cancer.
Bolin
T D
TD
Gastrointestinal Unit, Prince of Wales Hospital, Sydney, NSW.
Hunt
R H
RH
Korman
M G
MG
Lambert
J R
JR
Lee
A
A
Talley
N J
NJ
D000230:Adenocarcinoma / Q000209:etiology*; D004415:Dyspepsia / Q000209:etiology; D016481:Helicobacter Infections / Q000150:complications* / Q000175:diagnosis; D016480:Helicobacter pylori; D006801:Humans; D008223:Lymphoma / Q000209:etiology*; D013274:Stomach Neoplasms / Q000209:etiology*