title: Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level.
abstract: The effect of apolipoprotein E (apo E) common genotypes on fasting retinyl palmitate (RP) level was studied in 344 white individuals, of which 130 had intimal thickening of the carotid artery ("cases") and 214 were controls. In this sample the common apo E genotypes possessed a statistically significant effect on fasting RP level in cases, while in controls the effect observed was not statistically significant. It is suggested that the effect of apo E may be expressed at the level of remnant clearance particles. Additionally, in cases other traits interact with the apo E genotype to influence fasting RP level.
authors.affiliation: Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
authors.forename: A P
authors.initials: AP
authors.lastname: Surguchov
authors.forename: E
authors.initials: E
authors.lastname: Boerwinkle
authors.forename: A R
authors.initials: AR
authors.lastname: Sharrett
authors.forename: W
authors.initials: W
authors.lastname: Patsch
mesh_terms: D001057:Apolipoproteins E / Q000235:genetics*; D004224:Diterpenes; D005215:Fasting; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D011446:Prospective Studies; D000084562:Retinyl Esters; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D001057:Apolipoproteins E; D004224:Diterpenes; D000084562:Retinyl Esters; D014801:Vitamin A; C014794:retinol palmitate