title: Functions of fibroblast growth factors and their receptors.
abstract: Fibroblast growth factors were first characterized twenty years ago as mitogens of cultured fibroblasts. Despite a wealth of data from experiments in vitro, insights have begun to emerge only recently on the normal function of these growth factors in mice and humans, as a result of studies of natural and experimental mutations in the factors and their receptors.
authors.affiliation: Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
authors.forename: A O
authors.initials: AO
authors.lastname: Wilkie
authors.forename: G M
authors.initials: GM
authors.lastname: Morriss-Kay
authors.forename: E Y
authors.initials: EY
authors.lastname: Jones
authors.forename: J K
authors.initials: JK
authors.lastname: Heath
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005346:Fibroblast Growth Factors / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D008024:Ligands; D008969:Molecular Sequence Data; D009154:Mutation; D011487:Protein Conformation; D017468:Receptors, Fibroblast Growth Factor / Q000737:chemistry / Q000502:physiology*
chemical_list: D008024:Ligands; D017468:Receptors, Fibroblast Growth Factor; D005346:Fibroblast Growth Factors