title: Clear cell carcinoma simulating the "endometrioid-like variant" of yolk sac tumor.
abstract: The authors report a case of clear cell carcinoma of the ovary simulating the "endometrioid-like variant" of YST only recently described by Clement. The tumor was characterized histologically by a villoglandular component intermingled with an endometrioid like glandular pattern, nuclear pleomorphism with abnormal mitotic figures, eosinophilic hyaline PAS-D resistant bodies and diffuse, typical sopranuclear and subnuclear vacuolization according to Clement's description. Clinical features as the old age of the patient and laboratory investigations, suggested the possibility of a surface epithelial origin of the neoplasia, that was substantiated by subsequent additional sections and by immunohistochemical staining for AFP, AAT and CEA.
authors.affiliation: Servizio di Anatomia ed Istologia Patologica, Ospedale Civile, Rovigo.
authors.forename: M R
authors.initials: MR
authors.lastname: Ballotta
authors.forename: E
authors.initials: E
authors.lastname: Bianchini
authors.forename: L
authors.initials: L
authors.lastname: Borghi
authors.forename: R M
authors.initials: RM
authors.lastname: Fortini
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology*; D000328:Adult; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000473:pathology*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*