Spontaneous excitations in the visual cortex: stripes, spirals, rings, and collective bursts.
As a simple model of the cortical sheet, we study a locally connected net of spiking neurons. Refractoriness, noise, axonal delays, and the time course of excitatory and inhibitory postsynaptic potentials are taken into account explicitly. In addition to a low-activity state and depending on the synaptic efficacy, four different scenarios evolve spontaneously, viz., stripes, spirals, rings, and collective bursts. Our results can be related to experimental observations of drug-induced epilepsy and hallucinations.
Fohlmeister
C
C
Physik-Department der TU München, Germany.
Gerstner
W
W
Ritz
R
R
van Hemmen
J L
JL
D000200:Action Potentials; D000818:Animals; D001931:Brain Mapping; D006212:Hallucinations / Q000139:chemically induced / Q000503:physiopathology* / Q000523:psychology; D006213:Hallucinogens / Q000009:adverse effects / Q000494:pharmacology; D006801:Humans; D007649:Ketamine / Q000009:adverse effects / Q000494:pharmacology; D008238:Lysergic Acid Diethylamide / Q000009:adverse effects / Q000494:pharmacology; D008959:Models, Neurological; D008960:Models, Psychological; D009415:Nerve Net; D009474:Neurons / Q000502:physiology*; D010406:Penicillins / Q000494:pharmacology / Q000633:toxicity; D011817:Rabbits; D012160:Retina; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology / Q000523:psychology; D009435:Synaptic Transmission; D014793:Visual Cortex / Q000187:drug effects / Q000502:physiology*
D006213:Hallucinogens; D010406:Penicillins; D007649:Ketamine; D008238:Lysergic Acid Diethylamide