New crystal structures of nucleic acids and their complexes.
In the past year, X-ray crystallographic studies of representatives of all nucleic acid structural types have been reported. Among the most interesting structures are the parallel DNA tetraplex formed by d(TGGGGT), the four-stranded structure formed by d(CCCT) and a double drug bound side by side in an antiparallel orientation to the minor groove of a B-DNA. Certainly, the structure that has received most attention is that of the first complex of a ribozyme with an inhibitor DNA.
Wahl
M C
MC
Department of Biochemistry, Ohio State University, Columbus 43210-1002, USA.
Sundaralingam
M
M
D000818:Animals; D001483:Base Sequence; D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009696:Nucleic Acids / Q000737:chemistry*
D009696:Nucleic Acids