title: Successful surgical treatment of secondary Kwashiorkor after total gastrectomy: report of a case.
abstract: We report herein the case of a 56-year-old woman who developed secondary Kwashiorkor 9 years after undergoing a total gastrectomy for early gastric cancer. Until she began developing the symptoms of Kwashiorkor, including general fatigue, edema of the face and extremities, anemia, alopecia, and weight loss, she had been leading a normal life post-gastrectomy. Her symptoms were alleviated by total parenteral nutrition (TPN) therapy, but reappeared soon after TPN therapy was discontinued. Therefore, she required several subsequent courses of TPN. In an attempt to permanently resolve the ongoing Kwashiorkor symptoms, reconstructive surgery involving transposition of the jejunum from the previous Graham method to the interposition method was performed 10 years after the initial gastrectomy. After the second operation, her malnutrition was completely alleviated, and she has been in good health for the 8 years since. To our knowledge, there has been no other report of the symptoms of secondary Kwashiorkor after total gastrectomy being alleviated by altering the procedure of reconstruction of the intestinal tract. Thus, we recommend surgical treatment to alter the digestive continuity to a more physiological pathway for selected patients with secondary Kwashiorkor syndrome.
authors.affiliation: Second Department of Surgery, Dokkyo University School of Medicine, Tochigi, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Kadowaki
authors.forename: T
authors.initials: T
authors.lastname: Tajima
authors.forename: H
authors.initials: H
authors.lastname: Kogure
authors.forename: Y
authors.initials: Y
authors.lastname: Tajima
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D001798:Blood Proteins / Q000378:metabolism; D001835:Body Weight / Q000502:physiology; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D007732:Kwashiorkor / Q000601:surgery*; D008111:Liver Function Tests; D008875:Middle Aged; D011178:Postgastrectomy Syndromes / Q000601:surgery*; D012086:Reoperation; D012709:Serum Albumin / Q000378:metabolism; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D001798:Blood Proteins; D012709:Serum Albumin