title: Hemoglobin analysis by capillary zone electrophoresis.
abstract: The analysis of haemoglobin is routine in medical laboratories for the purpose of assessing blood disorders and related pathologies. Haemoglobin is structurally diverse and possesses many variant forms, some disease-producing. With recent improvements in technology, capillary electrophoresis is now being adapted in the clinical laboratory. This paper describes the analysis of haemoglobin variants using uncoated fused-silica capillaries. The effects of using different buffer salts at different concentrations with different buffer pH values to separate haemoglobin variants in these capillaries are described.
authors.affiliation: Düzen Laboratories, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Sahin
authors.forename: Y R
authors.initials: YR
authors.lastname: Laleli
authors.forename: R
authors.initials: R
authors.lastname: Ortancil
mesh_terms: D002021:Buffers; D004586:Electrophoresis / Q000379:methods*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D006863:Hydrogen-Ion Concentration
chemical_list: D002021:Buffers; D006454:Hemoglobins