title: Induced acute ruminal acidosis in goats treated with yeast (Saccharomyces cerevisiae) and bicarbonate.
abstract: Ruminal acidosis was induced in twenty-one 10-month-old West African Dwarf Goats by feeding a suspension of 80 g wheat flour per kg bodyweight (day 0) through a stomach tube. Ruminal and systemic acidosis was diagnosed on day 1 in all goats. Clinical signs included loss of rumination and appetite, trembling, and watery diarrhoea. The detection of acidic faeces during the first 24h was considered of diagnostic importance. Subgroups were treated orally on days 1, 2, and 3 either with 1 g of sodium bicarbonate per kg bodyweight, with 1 g of baking yeast per kg, or with a combination of these treatments at 0.5 g of each per kg. A fourth group served as untreated controls. Peroral bicarbonate neutralization was highly effective in the treatment of rumen acidosis, whereas the use of yeast was found ineffective. The combined treatment had a moderate effect probably due to the bicarbonate. Three fatal cases (60%) occurred in the untreated group compared with none in the bicarbonate group, and 2 in each of the remaining groups. This corresponded to 33% of the yeast treated group and 40% of the combined treated group. Details were given on post mortem examinations performed on all survivors on day 11. Lesions included subacute rumenitis and abomasal ulcers. No lesions were found in 3 of the bicarbonate treated goats and in 2 of the animals receiving combined treatment.
authors.affiliation: Department of Clinical Studies, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
authors.forename: V
authors.initials: V
authors.lastname: Aslan
authors.forename: S M
authors.initials: SM
authors.lastname: Thamsborg
authors.forename: R J
authors.initials: RJ
authors.lastname: Jørgensen
authors.forename: A
authors.initials: A
authors.lastname: Basse
mesh_terms: D000138:Acidosis / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D056890:Eukaryota / Q000502:physiology; D015511:Goat Diseases / Q000209:etiology / Q000628:therapy*; D006041:Goats; D006400:Hematocrit / Q000662:veterinary; D006863:Hydrogen-Ion Concentration; D008297:Male; D009994:Osmolar Concentration; D011180:Postmortem Changes; D012417:Rumen / Q000469:parasitology; D012441:Saccharomyces cerevisiae; D017693:Sodium Bicarbonate / Q000627:therapeutic use*; D013272:Stomach Diseases / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D014908:Triticum
chemical_list: D017693:Sodium Bicarbonate