[The effect of postnatal sympathectomy on the production and receptor binding of sex steroids in female rats during puberty].
The total chemical desympathization caused by injection of 6-hydroxydopamine in the first day of life increased the progesterone secretion, decreased the estradiol secretion and abolished translocation of estradiol receptors to the cell nuclei in the uterus of 1-2 days old rats, which correlated with the absence of uterus weight increase after exogenous estradiol injections. The peripheral desympathization caused by injection of neurotoxin to two weeks old rats induced only estradiol secretion decrease, but to the less extent than after total desympathization.
Savchenko
O N
ON
Proĭmina
F I
FI
Sekretareva
E V
EV
D000818:Animals; D000831:Animals, Newborn; D004958:Estradiol / Q000032:analysis / Q000378:metabolism*; D005260:Female; D010053:Ovary / Q000737:chemistry / Q000294:innervation / Q000378:metabolism; D016627:Oxidopamine; D011374:Progesterone / Q000032:analysis / Q000378:metabolism*; D011869:Radioligand Assay; D051381:Rats; D011959:Receptors, Estradiol / Q000032:analysis / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000032:analysis / Q000378:metabolism*; D012741:Sexual Maturation / Q000502:physiology*; D013563:Sympathectomy, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*; D014599:Uterus / Q000737:chemistry / Q000294:innervation / Q000378:metabolism
D011959:Receptors, Estradiol; D011980:Receptors, Progesterone; D011374:Progesterone; D004958:Estradiol; D016627:Oxidopamine
Vliianie postnatal'noĭ desimpatizatsii na produktsiiu i retseptsiiu polovykh steroidov u samok krys v period pubertata.