Primary systemic amyloidosis presenting with polyneuropathy characterized by very long survival.
We report a case of primary systemic amyloidosis associated with IgA monoclonal gammopathy presenting with sensorimotor polyneuropathy. For 10 years the neurological symptoms were the only clinical manifestation. A great deal of therapy was given right from the onset of symptoms and the very long survival of the patient may have been due to these efforts.
Rinaldi
R
R
Neurology Unit, S. Orsola-Malpighi Hospital, Bologna, Italy.
Azzimondi
G
G
Preda
P
P
Ricci
P
P
D'Alessandro
R
R
Pazzaglia
P
P
D000328:Adult; D017772:Amyloid Neuropathies / Q000175:diagnosis*; D000686:Amyloidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D004576:Electromyography; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A / Q000097:blood*; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008475:Median Nerve; D009431:Neural Conduction; D010951:Plasma Exchange; D013497:Sural Nerve / Q000648:ultrastructure; D013534:Survival
D007070:Immunoglobulin A; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide