Acute renal failure associated with Candida albicans infection.
A 16-year-old male with a long history of steroid-responsive nephrotic syndrome developed fever, abdominal pain, thrombocytopenia and acute renal failure. The clinical course and renal histology were similar to, but not typical of, haemolytic uremic syndrome. Positive cultures (throat, oesophagus, stool), an elevation in serum levels of specific antibody and fungal polysaccharide (1,3) beta-D-glucan and response to the antifungal therapy indicated an association between this syndrome and infection with Candida albicans.
Nishimoto
G
G
Department of Pediatric Nephrology, Tokyo Women's Medical College, Japan.
Tsunoda
Y
Y
Nagata
M
M
Yamaguchi
Y
Y
Yoshioka
T
T
Ito
K
K
D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000293:Adolescent; D002177:Candidiasis / Q000150:complications*; D005936:Glucans / Q000097:blood; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications; D006435:Renal Dialysis; D047071:beta-Glucans
D005936:Glucans; D047071:beta-Glucans; C033363:beta-1,3-glucan