title: Successful treatment with ganciclovir of presumed Epstein-Barr meningo-encephalitis following bone marrow transplant.
abstract: Epstein-Barr virus-specific polymerase chain reaction was used to diagnose EBV-meningo-encephalitis in a bone marrow transplant recipient. The patient made complete recovery with ganciclovir treatment. Pitfalls in diagnosis with EBV-PCR and the potential therapeutic efficacy of ganciclovir in EBV infections are discussed.
authors.affiliation: Department of Neuro-oncology, Dr. Daniël Den Hoed Cancer Center, Rotterdam, The Netherlands.
authors.forename: P L
authors.initials: PL
authors.lastname: Dellemijn
authors.forename: A
authors.initials: A
authors.lastname: Brandenburg
authors.forename: H G
authors.initials: HG
authors.lastname: Niesters
authors.forename: M J
authors.initials: MJ
authors.lastname: van den Bent
authors.forename: P H
authors.initials: PH
authors.lastname: Rothbarth
authors.forename: L T
authors.initials: LT
authors.lastname: Vlasveld
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use*; D006566:Herpesviridae Infections / Q000188:drug therapy*; D004854:Herpesvirus 4, Human; D006801:Humans; D008590:Meningoencephalitis / Q000188:drug therapy*; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000188:drug therapy*
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir