[Induced expectoration: its role in the diagnosis of pneumocystis carinii pneumonia].
OBJECTIVE
The purpose of this retrospective study was to describe the changes and the effect of Pneumocystis carinii pneumonia (PCP) prophylaxis on induced sputum sensitivity during these five last years


METHODS
An induced sputum examination was performed in 80 cases of PCP over a 5-year period.


RESULTS
The induced sputum were positive in 30 cases (sensitivity = 37.5%). This sensitivity changed very little during these five years. Thirty of these 80 patients (37.5%) received PCP prophylaxis at least for four weeks before PCP diagnosis. Induced sputum sensitivity was 50% in the group with prophylaxis versus 30% in the group without prophylaxis (p = 0.073).


CONCLUSIONS
In our institution, the induced sputum examination remains an interesting diagnostic procedure for PCP. PCP prophylaxis does not seem to have effects on induced sputum sensitivity.
Cabié
A
A
Service des Maladies infectieuses et tropicales, Hôpital Bichat, Claude Bernard, Paris.
Mendoza-Sassi
G
G
Matheron
S
S
Dombret
M C
MC
Coulaud
J P
JP
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000336:Aerosols; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology*; D006801:Humans; D010419:Pentamidine / Q000627:therapeutic use; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control; D012189:Retrospective Studies; D012462:Saline Solution, Hypertonic / Q000494:pharmacology; D013183:Sputum / Q000187:drug effects / Q000382:microbiology*
D000336:Aerosols; D012462:Saline Solution, Hypertonic; D010419:Pentamidine
Expectorations induites: intérêt pour le diagnostic des pneumocystoses pulmonaires.