Response to interferon therapy in children with chronic hepatitis C.
We evaluated the effect of interferon therapy and investigated factors that may influence the outcome in 18 children with chronic hepatitis C. A complete response was obtained in 10 children (56%). The titer for pretreatment serum virus ribonucleic acid (< or = 10(7) copies/ml) was correlated significantly with a complete response to therapy.
Fujisawa
T
T
Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Inui
A
A
Ohkawa
T
T
Komatsu
H
H
Miyakawa
Y
Y
Onoue
M
M
D000410:Alanine Transaminase / Q000097:blood / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005838:Genotype; D006526:Hepatitis C / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007075:Immunoglobulin M; D007372:Interferons / Q000627:therapeutic use*; D008099:Liver / Q000201:enzymology / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D016133:Polymerase Chain Reaction; D012367:RNA, Viral; D016896:Treatment Outcome
D007075:Immunoglobulin M; D012367:RNA, Viral; D007372:Interferons; D000410:Alanine Transaminase