Improving the management of hypertension in clinical practice.
Antihypertensive therapy is unquestionably beneficial, but current management of hypertension does not reduce cardiovascular risk to normotensive levels. Treatment of the hypertensive patient may be improved by a number of measures. These include control of SBP as well as DBP, with reduction to < 140/90 mmHg. Treatment of concomitant diseases and of other risk factors is likely to be of benefit, as is 24 h control of BP. Variability of BP appears to influence clinical outcome, but it is unclear whether this can be reduced by treatment. Poor patient compliance with treatment instructions may be an important factor in disappointing therapeutic performance, but could be improved with less complex treatment regimens.
Mancia
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Cattedra di Medicina Interna, University of Milan, Ospedale San Gerardo, Monza, Italy.
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods; D002318:Cardiovascular Diseases / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D010349:Patient Compliance; D011364:Professional Practice; D011785:Quality Assurance, Health Care; D012307:Risk Factors
D000959:Antihypertensive Agents