[Study on effect of polysaccharides of ginseng on peripheral blood mononuclear cell induced interleukin-2 production and activity of its receptors in vitro].
To study the effect of polysaccharides of Ginseng (PSG) on cellular-immunity from healthy subjects and patients of kidney disease, the peripheral blood mononuclear cell (PBMC) induced interleukin-2 (IL-2) were assayed in vitro. It was found that the PSG could prommote the PBMC induced IL-2 in the healthy subjects and patients with kidney diseases and was dose-dependent. This study revealed that PSG was worthwhile to be further studied as an approach of biological responsive modifier therepy in treating human immunodeficiency diseases.
Ma
L
L
Dept. of Nephrology, 281 Hospital of PLA, Hebei.
Zhou
Z L
ZL
Yang
Q
Q
D000293:Adolescent; D000328:Adult; D005260:Female; D006505:Hepatitis / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007376:Interleukin-2 / Q000096:biosynthesis*; D007674:Kidney Diseases / Q000276:immunology / Q000821:virology; D007676:Kidney Failure, Chronic / Q000276:immunology; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D005894:Panax / Q000737:chemistry; D010946:Plants, Medicinal; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D015375:Receptors, Interleukin-2 / Q000378:metabolism
D007376:Interleukin-2; D011134:Polysaccharides; D015375:Receptors, Interleukin-2