Synaptic plasticity: hippocampal LTP.
One of the most intensively studied forms of synaptic plasticity is long-term potentiation (LTP). The past year has seen further evidence advanced on both sides of the presynaptic/postsynaptic locus of expression debate, without an obvious path to reconcile the two views. Real progress has been made, however, in clarifying the possible role of nitric oxide as a retrograde messenger and the cellular location of its synthetic enzyme. Intriguing glimpses of the complex involvement of metabotropic glutamate receptors in the induction of LTP have also appeared.
Larkman
A U
AU
University of Laboratory of Physiology, Oxford University, UK.
Jack
J J
JJ
D000818:Animals; D006624:Hippocampus / Q000502:physiology*; D017774:Long-Term Potentiation / Q000502:physiology*; D009569:Nitric Oxide / Q000378:metabolism; D018094:Receptors, Metabotropic Glutamate / Q000502:physiology; D013569:Synapses / Q000502:physiology*
D018094:Receptors, Metabotropic Glutamate; D009569:Nitric Oxide