title: Bacterial agents isolated from cerebrospinal fluid of patients with acquired immunodeficiency syndrome (AIDS) and neurological complications.
abstract: Cerebrospinal fluid (CSF) samples from 2083 patients with acquired immunodeficiency syndrome (AIDS) and neurological complications were bacteriologically examined during a period of 7 years (1984-1990). The percentage of patients who had at least one bacterial agent cultured from the CSF was 6.2%. Mycobacterium tuberculosis was the most frequently isolated agent (4.3%), followed by Mycobacterium avium complex or MAC (0.7%), Pseudomonas spp (0.5%), Enterobacter spp (0.4%), and Staphylococcus aureus (0.3%). Among 130 culture positive patients, 89 (68.5%) had M. tuberculosis and 15 (11.6%) had MAC. The frequency of bacterial isolations increased from 1988 (5.2%) to 1990 (7.2%), partly due to the increase in MAC isolations. Bacterial agents were more frequently isolated from patients in the age group 21-30 years and from women (p < 0.05).
authors.affiliation: Seção de Bacteriologia, Instituto Adolfo Lutz, São Paulo, Brasil.
authors.forename: I M
authors.initials: IM
authors.lastname: Landgraf
authors.forename: M
authors.initials: M
authors.lastname: Palaci
authors.forename: M F
authors.initials: MF
authors.lastname: Vieira
authors.forename: S Y
authors.initials: SY
authors.lastname: Ueki
authors.forename: M C
authors.initials: MC
authors.lastname: Martins
authors.forename: D N
authors.initials: DN
authors.lastname: Sato
authors.forename: L
authors.initials: L
authors.lastname: Ferrazoli
authors.forename: M A
authors.initials: MA
authors.lastname: Telles
authors.forename: M C
authors.initials: MC
authors.lastname: Gorla
authors.forename: T M
authors.initials: TM
authors.lastname: Vaz
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000134:cerebrospinal fluid* / Q000150:complications / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001424:Bacterial Infections / Q000134:cerebrospinal fluid* / Q000150:complications; D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid* / Q000150:complications / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D012737:Sex Factors