Sequence of a chicken erythroblast mono(ADP-ribosyl)transferase-encoding gene and its upstream region.
We have cloned the MADPRT gene encoding the 300-amino-acid mono(ADP-ribosyl)transferase (MADPRT) from chicken erythroblasts. The protein has homology to the rabbit and human skeletal muscle (50% identity) and two chicken heterophil (52% identity) NAD+:arginine MADPRT. The active site region is particularly conserved. The upstream region of the MADPRT gene from erythroblasts has several features characteristic of promoter sequences.
Davis
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Cell and Molecular Biology Laboratory, University of Sussex, Brighton, UK.
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D036002:ADP Ribose Transferases / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens / Q000235:genetics*; D016384:Consensus Sequence; D017124:Conserved Sequence; D004900:Erythroblasts / Q000201:enzymology*; D006801:Humans; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000201:enzymology; D011401:Promoter Regions, Genetic; D011817:Rabbits; D017386:Sequence Homology, Amino Acid; D016385:TATA Box
D036002:ADP Ribose Transferases