title: Prototyping a genetics deductive database.
abstract: We are developing a laboratory notebook system known as the Genetics Deductive Database. Currently our prototype provides storage for biological facts and rules with flexible access via an interactive graphical display. We have introduced a formal basis for the representation and reasoning necessary to order genome map data and handle the uncertainty inherent in biological data. We aim to support laboratory activities by introducing an experiment planner into our prototype. The Genetics Deductive Database is built using new database technology which provides an object-oriented conceptual model, a declarative rule language, and a procedural update language. This combination of features allows the implementation of consistency maintenance, automated reasoning, and data verification.
authors.affiliation: Advanced Computation Laboratory, Imperial Cancer Research Fund, London, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Hearne
authors.forename: Z
authors.initials: Z
authors.lastname: Cui
authors.forename: S
authors.initials: S
authors.lastname: Parsons
authors.forename: S
authors.initials: S
authors.lastname: Hajnal
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003628:Database Management Systems; D016208:Databases, Factual; D016678:Genome; D006801:Humans