title: A new reciprocal translocation (7q+;15q-) in the domestic pig.
abstract: A reciprocal translocation was identified in a phenotypically normal Large White boar. Chromosome preparations from the carrier were studied by flow sorting, chromosome painting and G-banding. The flow karyotype displayed one additional clearly distinguishable peak, while in situ hybridization and G-banding showed two abnormal chromosomes involved in the translocation. All the results suggested that the translocation involved chromosomes 7 and 15 and the karyotype investigated was 38,XY,rcp(7;15)(q24;q12). The parents and three full sibs of the carrier had normal karyotypes. It would seem that the translocation had arisen de novo.
authors.affiliation: Department of Immunology, Babraham Institute, Cambridge, UK.
authors.forename: G D
authors.initials: GD
authors.lastname: Konfortova
authors.forename: N G
authors.initials: NG
authors.lastname: Miller
authors.forename: E M
authors.initials: EM
authors.lastname: Tucker
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D005434:Flow Cytometry; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D013552:Swine / Q000235:genetics*; D014178:Translocation, Genetic