title: Anti-lymphocyte globulin therapy in aplastic anaemia--a university hospital experience.
abstract: Antilymphocyte globulin (ALG) was given every other day for 5 doses with platelet transfusions immediately following ALG administration in 6 patients with aplastic anaemia. Four patients responded and 3 durable remissions were achieved. One patient relapsed and further treatment with anti-thymocyte globulin and cyclosporin also failed. One patient died of Flavobacterium septicaemia 6 days after completion of ALG. Our data suggests that using an alternate day regimen, a response rate similar to a daily regimen can be obtained.
authors.affiliation: Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
authors.forename: K W
authors.initials: KW
authors.lastname: Leong
authors.forename: A
authors.initials: A
authors.lastname: Teh
authors.forename: J J
authors.initials: JJ
authors.lastname: Bosco
authors.forename: S
authors.initials: S
authors.lastname: Jayaranee
authors.forename: U
authors.initials: U
authors.lastname: Sadat
mesh_terms: D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000628:therapy*; D000961:Antilymphocyte Serum / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008297:Male; D017713:Platelet Transfusion; D016896:Treatment Outcome
chemical_list: D000961:Antilymphocyte Serum