IgG antibodies to bovine serum albumin are not increased in children with IDDM.
IgG antibodies to bovine serum albumin (BSA) were measured in 91 serum samples from children 4-17 years of age with newly diagnosed insulin-dependent diabetes mellitus (IDDM). A total of 80 healthy 12-year-old children served as control subjects. BSA antibody values > 3 SDs were obtained in 6 IDDM patients and 3 control subjects (P = 0.50), and values > 2 SDs were obtained in 12 IDDM patients and 4 control subjects (P = 0.11). In conclusion, IgG antibodies to BSA were not significantly increased at onset of diabetes.
Ivarsson
S A
SA
Department of Experimental Research, University of Lund, Sweden.
Månsson
M U
MU
Jakobsson
I L
IL
D000293:Adolescent; D000818:Animals; D000917:Antibody Formation; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000097:blood*; D012016:Reference Values; D012710:Serum Albumin, Bovine / Q000276:immunology* / Q000494:pharmacology
D007074:Immunoglobulin G; D012710:Serum Albumin, Bovine