[Histology of the respiratory system after exposure to bacterial infection and formalin vapors used to induce experimental bronchospasm].
The purpose of the research was to observe the influence of the bacterial infection and inhalation vapours on the histologic picture of bronchi and lungs in the course on the experimental asthma induced in guinea pigs. The animals were divided into 6 groups. The animals were immunized by ovalbumin. Group I was control and was subjected to inhalations of physiologic salt solutions. Group II was immunized by the soluble of ovalbumin intraperitoneally and was inhaled with the solution of ovalbumin. Group III was subjected only to inhalation of the ovalbumin. Group IV was inhaled with the solution of formalin alternately. Group V experienced only formalin inhalations. Group VI was infected with Pseudomonas aeruginosa strain and inhaled with the solution of ovalbumin. On the histologic examination of the lung tissue the authors found the atrophy of the lymphatic system, the hypertrophy of the mucous membrane and muscular coat of the bronchi, the accumulation of large amount of mucus in their lumen and the exfoliation of the bronchial epithelium.
Sachs
K
K
Katedry i Kliniki Chorób Wewnetrznych i Alergologii Slaskiej Akademii Medycznej w Katowicach.
Pindel
B
B
Jastrzab
J
J
Gawlik
R
R
Rogala
E
E
D000818:Animals; D001249:Asthma / Q000209:etiology / Q000473:pathology*; D001284:Atrophy; D001980:Bronchi / Q000473:pathology*; D001986:Bronchial Spasm / Q000209:etiology* / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005557:Formaldehyde; D006168:Guinea Pigs; D006984:Hypertrophy; D008168:Lung / Q000473:pathology*; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D010047:Ovalbumin; D011552:Pseudomonas Infections / Q000150:complications*
D005557:Formaldehyde; D010047:Ovalbumin
Obraz histologiczny struktur układu oddechowego po ekspozycji na zakazenia bakteryjne i pary formaliny wywołujace doświadczalny model skurczu oskrzeli.