Gelatin particle indirect agglutination test for serodiagnosis of schistosomiasis: comparative study with enzyme-linked immunosorbent assay.
A new serological test, the gelatin particle agglutination test (GPAT), was used for the serodiagnosis of schistosomiasis mansoni. This technique showed the sensitivity (90.6%) and specificity (97.8%) close to those of enzyme-linked immunosorbent assay. The GPAT can be easily and rapidly performed without specialized equipment, by using lyophilized antigen-coated gelatin particles. The test also seems to be useful for mass screening of Schistosoma infection in field conditions.
Kobayashi
J
J
Laboratório de Imuno-Parasitologia, Gastrocentro, State University of Campinas, Campinas, SP, Brasil.
Carrilho
F J
FJ
Shimabukuro
T
T
da Silva
L C
LC
Soares
E C
EC
Nishimura
N F
NF
Chieffi
P P
PP
Sato
Y
Y
D000372:Agglutination Tests / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D005780:Gelatin; D006801:Humans; D012555:Schistosomiasis mansoni / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D005780:Gelatin