[Possible role of threonine metabolism in tetracycline biosynthesis].
The review presents the data on the metabolism of threonine and branched amino acids in actinomycetes. The data substantiate the hypothesis on the catabolism of carbohydrates through oxaloacetate--aspartate--threonine--ketomethyl valerate as an alternative pathway in the formation of acetyl-coA in the cells of tetracycline-producing cultures.
Mironov
V A
VA
Bobyleva
R I
RI
Danilenko
V N
VN
D000105:Acetyl Coenzyme A / Q000096:biosynthesis; D000190:Actinomyces / Q000378:metabolism; D013302:Streptomyces / Q000378:metabolism; D013754:Tetracyclines / Q000096:biosynthesis*; D013912:Threonine / Q000378:metabolism*
D013754:Tetracyclines; D013912:Threonine; D000105:Acetyl Coenzyme A
Vozmozhnaia rol' metabolisma treonina v biosinteze tetratsiklinov.