title: Responders and nonresponders to transurethral microwave thermotherapy: a multicenter retrospective analysis.
abstract: OBJECTIVE
  We attempted to identify any parameter that could possibly lead to a successful treatment outcome after transurethral microwave thermotherapy.
  
  
  METHODS
  Clinical parameters and treatment profiles of 292 patients were analyzed in a retrospective multicenter manner. Responder and nonresponder groups were identified according to a given definition.
  
  
  RESULTS
  No statistically significant differences in baseline characteristics were found. Responders showed a 76% symptomatic improvement rate compared to 27% in nonresponders, and an 82% improvement rate in peak flow compared to a 5% decrease in nonresponders. Responders also showed a significantly greater increase in posttreatment PSA level and a significantly greater amount of energy released during treatment.
  
  
  CONCLUSIONS
  No baseline clinical parameter is capable of predicting treatment outcome.
authors.affiliation: Department of Urology, Nijmegen University Hospital, The Netherlands.
authors.forename: M J
authors.initials: MJ
authors.lastname: de Wildt
authors.forename: A
authors.initials: A
authors.lastname: Tubaro
authors.forename: K
authors.initials: K
authors.lastname: Höfner
authors.forename: S S
authors.initials: SS
authors.lastname: Carter
authors.forename: J J
authors.initials: JJ
authors.lastname: de la Rosette
authors.forename: M
authors.initials: M
authors.lastname: Devonec
mesh_terms: D000368:Aged; D003972:Diathermy / Q000379:methods*; D006801:Humans; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000628:therapy*; D012074:Remission Induction; D012189:Retrospective Studies; D016896:Treatment Outcome; D014521:Urethra