title: Effect of drink temperature on antropyloroduodenal motility and gastric electrical activity in humans.
abstract: There is little information on the motor mechanisms underlying the effects of meal temperature on gastric emptying. The effects on antropyloric pressures and the surface electrogastrogram of ingesting drinks at 4 degrees C, 37 degrees C, and 50 degrees C (350 ml normal saline and 50 ml low calorie (7 kj) orange cordial) given in randomised order were measured over 60 minutes in 12 normal volunteers (10 men and 2 women, aged 18-55 years). The warm and cold drinks suppressed antral pressure waves (p < 0.05), altered the organisation of antropyloric pressure waves (p < 0.05), stimulated isolated pyloric pressure waves (p < 0.05), and increased electrogastrogram frequency (p < 0.05) when compared with the 37 degrees C drink. These changes were greatest in the first 30 minutes after ingestion and greater (p < 0.05) with the 4 degrees C drink. Temperature has major effects on postprandial antropyloroduodenal motility in normal subjects. Both cold and warm drinks stimulate a pattern of motility associated with retardation of transpyloric flow.
authors.affiliation: Gastroenterology Unit, Royal Adelaide Hospital, SA, Australia.
authors.forename: W M
authors.initials: WM
authors.lastname: Sun
authors.forename: R
authors.initials: R
authors.lastname: Penagini
authors.forename: G
authors.initials: G
authors.lastname: Hebbard
authors.forename: C
authors.initials: C
authors.lastname: Malbert
authors.forename: K L
authors.initials: KL
authors.lastname: Jones
authors.forename: S
authors.initials: S
authors.lastname: Emery
authors.forename: J
authors.initials: J
authors.lastname: Dent
authors.forename: M
authors.initials: M
authors.lastname: Horowitz
mesh_terms: D000293:Adolescent; D000328:Adult; D003080:Cold Temperature; D004326:Drinking; D004386:Duodenum / Q000502:physiology; D004594:Electrophysiology; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011706:Pyloric Antrum / Q000502:physiology; D013270:Stomach / Q000502:physiology*