[Changes in the number of alpha 2- and beta-adrenoreceptors in the brain stem and cerebral cortex of rats in ontogeny].
Densities of alpha 2- and beta-adrenoceptors were higher in the brain stem of 21-day-old foetuses. The beta-receptors density, however, increased more rapidly in the brain stem after birth. The alpha 2-adrenergic receptors density gradually elevated with ageing in the cortex, the specifics of their ontogenesis being related to regulation of noradrenergic nerve cells function while that of the beta-adrenoceptors reflected a formation of adrenergic synapses in the brain areas in the course of development.
Iushkova
A A
AA
Dygalo
N N
NN
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000375:Aging / Q000187:drug effects; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D001933:Brain Stem / Q000737:chemistry* / Q000187:drug effects; D002540:Cerebral Cortex / Q000737:chemistry* / Q000187:drug effects; D003000:Clonidine / Q000494:pharmacology; D004082:Dihydroalprenolol / Q000494:pharmacology; D005333:Fetus; D008297:Male; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D018341:Receptors, Adrenergic, alpha-2 / Q000032:analysis* / Q000187:drug effects; D011943:Receptors, Adrenergic, beta / Q000032:analysis* / Q000187:drug effects
D000316:Adrenergic alpha-Agonists; D000319:Adrenergic beta-Antagonists; D018341:Receptors, Adrenergic, alpha-2; D011943:Receptors, Adrenergic, beta; D004082:Dihydroalprenolol; D011433:Propranolol; D003000:Clonidine
Izmeneniia chisla al'fa 2- i beta-adrenoretseptorov stvola i kory golovnogo mozga krys v ontogeneze.