Nimodipine levels in breast milk.
Nimodipine is an established drug in the treatment of symptomatic subarachnoid haemorrhage. However no data exist as to whether the drug has been detected in breast milk. This paper reports on a lactating patient who was commenced on nimodipine for a symptomatic arterial spasm after aneurysm surgery. Assays demonstrated that nimodipine was detected in the breast milk in relatively similar concentrations to plasma.
Tonks
A M
AM
Department of Neurosurgery, Auckland Public Hospital, New Zealand.
D000328:Adult; D017542:Aneurysm, Ruptured / Q000150:complications / Q000628:therapy; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000737:chemistry*; D009553:Nimodipine / Q000008:administration & dosage / Q000032:analysis*; D009880:Ophthalmic Artery / Q000601:surgery; D011182:Postoperative Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology / Q000628:therapy; D013345:Subarachnoid Hemorrhage / Q000209:etiology / Q000628:therapy
D009553:Nimodipine