title: Synthesis of some pyrido- and pyrazino-benzimidazole derivatives and their antifungal activity.
abstract: Some 2-aryl-4-hydroxypyrido[1,2-a]benzimidazole and 1-substituted 3-arylpyrazino-[1,2-a]benzimidazole derivatives were synthesized using 1-(2-arylethan-2-on)-2-acylbenzimidazole derivatives as starting materials. Antifungal activities of the compounds obtained were examined in vitro.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Anadolu, Eskişehir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Demirayak
authors.forename: K
authors.initials: K
authors.lastname: Güven
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011719:Pyrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D001562:Benzimidazoles; D011719:Pyrazines; D011725:Pyridines