Hammerhead ribozyme structure: U-turn for RNA structural biology.
Two crystal structures of the hammerhead ribozyme provide the first atomic-resolution views of an RNA active site, and suggest that the catalytic center may reside in a U-turn motif which was first seen in tRNA(Phe).
Doudna
J A
JA
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06522, USA.
D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D002413:Cations, Divalent; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D016337:RNA, Catalytic / Q000737:chemistry* / Q000378:metabolism; D012266:Ribose
D002413:Cations, Divalent; D016337:RNA, Catalytic; D012266:Ribose