Neuropeptides in the adrenal gland: distribution, localization of receptors, and effects on steroid hormone synthesis.
In this review we defined and classified the neuropeptides (NPs) related to the adrenal gland, according to Palkovits (Frontiers Neuroendocrinol 10:1 1988). The concentration (RIA) and distribution (immunohistochemistry) of NPs, as well as the localization of the receptors (radioligand studies) were summarized. Direct effects of NPs on aldosterone and corticosterone synthesis obtained by in vivo, in situ perfusion, and in vitro experimental approaches were reviewed. Data (from different rat strains and genders) for 35 NPs are presented.
Tóth
I E
IE
Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest.
Hinson
J P
JP
D000450:Aldosterone / Q000096:biosynthesis*; D000595:Amino Acid Sequence; D000818:Animals; D003345:Corticosterone / Q000096:biosynthesis*; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000032:analysis / Q000494:pharmacology*; D051381:Rats; D011921:Rats, Inbred WKY; D017207:Rats, Sprague-Dawley; D018013:Receptors, Neuropeptide / Q000032:analysis*
D009479:Neuropeptides; D018013:Receptors, Neuropeptide; D000450:Aldosterone; D003345:Corticosterone