Sinus histiocytosis with massive lymphadenopathy localized to the sella.
Sinus histiocytosis with massive lymphadenopathy (SHML) is a condition of unknown aetiology characterized by proliferation of histiocytes and lymphocytes, with the former phagocytosing the latter producing a typical histological appearance. Although first described in lymph nodes, cases have been reported in many extranodal sites, including the central nervous system. We report a case of SHML involving the sella turcica producing diabetes inspidus and pituitary dysfunction.
Ng
H K
HK
Department of Anatomical & Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong.
Poon
W S
WS
D000328:Adult; D001707:Biopsy, Needle; D003919:Diabetes Insipidus / Q000473:pathology*; D003937:Diagnosis, Differential; D006644:Histiocytes / Q000473:pathology; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D010587:Phagocytosis / Q000502:physiology; D010900:Pituitary Diseases / Q000473:pathology*; D010901:Pituitary Function Tests; D012658:Sella Turcica / Q000473:pathology*