The in vivo response of foetal tendons to sutures.
The in vivo response of foetal flexor digitorum profundus tendons to tendon sutures was studied macroscopically and microscopically in foetal lambs. No tendon adhesions were noted at any of the examination intervals. 4 days after injury, a mild inflammatory reaction was noted around the suture. The tendon examined at the 4-week interval showed evidence of migration of epitenon cells from the outer surface of the tendon into the suture track. The tendon examined at the 6-week interval showed normal tendon fibres surrounding the suture site. Differences between foetal skin and foetal tendon healing are discussed along with the possible role of amniotic fluid in modulating the healing process in the foetus.
al-Qattan
M M
MM
Division of Plastic Surgery, Riyadh, Saudi Arabia.
Posnick
J C
JC
Lin
K Y
KY
D000818:Animals; D002921:Cicatrix / Q000196:embryology / Q000473:pathology; D005260:Female; D006614:Hindlimb / Q000196:embryology / Q000601:surgery; D008859:Microscopy, Polarization; D011247:Pregnancy; D012756:Sheep; D013536:Suture Techniques; D013710:Tendons / Q000196:embryology* / Q000473:pathology / Q000601:surgery; D014945:Wound Healing / Q000502:physiology*