High-dose-rate intraoperative radiation therapy for colorectal cancer.
Last month, the authors presented the principles of high-dose-rate intraoperative radiation therapy (HDR-IORT), a new approach to intraoperative radiation delivery, as well as their criteria for patient selection, the goals of surgery, and their approach to minimizing surgical morbidity. This month, the authors present the technical aspects of delivering HDR intraoperative brachytherapy, their dosimetry atlas, and their results using HDR-IORT in the treatment of patients with colorectal cancer.
Harrison
L B
LB
Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Enker
W E
WE
Anderson
L L
LL
D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000601:surgery; D001918:Brachytherapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D015179:Colorectal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D004867:Equipment Design; D005500:Follow-Up Studies; D006801:Humans; D007432:Intraoperative Period; D016018:Least-Squares Analysis; D007902:Length of Stay; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted