[The effect of tetrachloromethane and ethanol on the release by rat splenocytes of immunomodulating factors].
In combined introduction tetrachloromethane (TCM) and ethanol the spleen cells secrete both immunostimulating agent with a molecular mass (MM) of 10 - 25 kD and immunosuppressing agents with MM > 100 kD. Sticking and nonsticking to the glass splenocytes of the animal affected by TCM and ethanol, excrete, respectively, the immunostimulating or immunosuppressing agents to the supernatant liquid of the splenocytes.
Smakhtin
M Iu
MIu
Konoplia
A I
AI
Chalyĭ
G A
GA
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000378:metabolism*; D000818:Animals; D002251:Carbon Tetrachloride / Q000633:toxicity*; D002448:Cell Adhesion; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology / Q000276:immunology; D002908:Chronic Disease; D000431:Ethanol / Q000633:toxicity*; D007114:Immunization; D007166:Immunosuppressive Agents; D008970:Molecular Weight; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000187:drug effects* / Q000378:metabolism*; D018709:Statistics, Nonparametric
D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents; D000431:Ethanol; D002251:Carbon Tetrachloride
Vliianie tetrakhlormetana i étanola na vydelenie splenotsitami krys immunomoduliruiushchikh faktorov.