[RANTES expression on human bronchial epithelial cells].
Viral infection induces airway inflammation. It is possible that bronchial epithelium derived chemokine contributes to the migration and accumulation of inflammatory cells in the airway viral infection. We infected bronchial epithelial cells with influenza virus and analysed mRNA expression and production of RANTES. The expression of mRNA and the production of RANTES were detected in infected cells using RT-PCR method and ELISA.
Matsukura
S
S
First Department of Internal Medicine, School of Medicine, Showa University.
Kokubu
F
F
Izumi
H
H
Noda
H
H
Kurokawa
M
M
Tokunaga
H
H
Adachi
M
M
D001980:Bronchi / Q000276:immunology* / Q000821:virology; D002478:Cells, Cultured; D018946:Chemokine CCL5 / Q000235:genetics / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D004848:Epithelium / Q000276:immunology / Q000821:virology; D006801:Humans; D009980:Influenza A virus; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000378:metabolism
D018946:Chemokine CCL5; D012333:RNA, Messenger