title: The structure, biochemistry, and metabolism of osteoarthritic cartilage: a review of the literature.
abstract: To understand the possible significance of the presence of proteases, cytokines, growth factors, and arachidonic acid metabolites in the osteoarthritic temporomandibular joint (TMJ), the pathogenesis of TMJ osteoarthritis (OA) is discussed, based on knowledge of structure, biochemistry and metabolism of osteoarthritic cartilage in general, and a classification of TMJ OA is presented.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Hospital, Groningen, The Netherlands.
authors.forename: L C
authors.initials: LC
authors.lastname: Dijkgraaf
authors.forename: L G
authors.initials: LG
authors.lastname: de Bont
authors.forename: G
authors.initials: G
authors.lastname: Boering
authors.forename: R S
authors.initials: RS
authors.lastname: Liem
mesh_terms: D001095:Arachidonic Acids / Q000378:metabolism; D001669:Biochemical Phenomena; D001671:Biochemistry; D002358:Cartilage, Articular / Q000378:metabolism* / Q000473:pathology*; D016207:Cytokines / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D006133:Growth Substances / Q000378:metabolism; D006801:Humans; D010003:Osteoarthritis / Q000145:classification / Q000209:etiology / Q000378:metabolism* / Q000473:pathology*; D013705:Temporomandibular Joint Disorders / Q000145:classification / Q000209:etiology / Q000378:metabolism* / Q000473:pathology*
chemical_list: D001095:Arachidonic Acids; D016207:Cytokines; D006133:Growth Substances; D010450:Endopeptidases