title: [An epidemiological study on blood viscosity and intraerythrocytic calcium in a group of high-school students selected according to their family histories].
abstract: An epidemiological study was performed in a group of secondary school students selected according to their family history to assess whether changes exist in blood viscosity and intraerythrocytic calcium levels in young healthy subjects with positive family histories of arterial hypertension or cerebral and cardiac ischemic vasculopathies, compared to a control group with a negative family history of these disorders. A population of 130 secondary school students without any pathologies were subdivided into 4 groups: 1) with a positive family history of ischemic cardiopathy (ICP); with a positive family history of cerebral ictus; 3) with a family history of arterial hypertension; 4) a negative family history of these diseases. Total blood viscosity, hematocrit, plasma fibrinogen and intraerythrocytic calcium was evaluated in all groups. The results show that these parameters were within the normal range, as was to be expected in healthy subjects. Blood viscosity was also normal in all groups; intraerythrocytic calcium levels were slightly higher in groups with histories of cardiovascular disease and in particular there was an increased percentage of cases with values above the threshold level. Higher fibrinogen levels were also recorded, but always within the normal range, in the group with a positive history of ICP. The epidemiological study is important to assess whether a family pattern of cardiovascular disease can also influence such independent risk parameters as blood viscosity and intraerythrocyte calcium, owing to the possible greater frequency of development of cardiovascular disease.
authors.affiliation: Istituto di Semeiotica Medica e Geriatria, Università degli Studi di Siena, Policlinico, Le Scotte.
authors.forename: V
authors.initials: V
authors.lastname: Turchetti
authors.forename: F
authors.initials: F
authors.lastname: Leoncini
authors.forename: C
authors.initials: C
authors.lastname: De Matteis
authors.forename: F
authors.initials: F
authors.lastname: Picciolini
authors.forename: G
authors.initials: G
authors.lastname: Postorino
authors.forename: R
authors.initials: R
authors.lastname: Altavilla
authors.forename: L
authors.initials: L
authors.lastname: Trabalzini
authors.forename: M
authors.initials: M
authors.lastname: Guerrini
authors.forename: S
authors.initials: S
authors.lastname: Forconi
mesh_terms: D000293:Adolescent; D001809:Blood Viscosity; D002545:Brain Ischemia / Q000097:blood / Q000453:epidemiology / Q000235:genetics; D002118:Calcium / Q000097:blood*; D004912:Erythrocytes / Q000737:chemistry*; D005340:Fibrinogen / Q000032:analysis; D006400:Hematocrit; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000453:epidemiology / Q000235:genetics; D007558:Italy / Q000453:epidemiology; D017202:Myocardial Ischemia / Q000097:blood / Q000453:epidemiology / Q000235:genetics
chemical_list: D005340:Fibrinogen; D002118:Calcium
vernacular_title: Indagine epidemiologica sulla viscosità ematica e sul calcio intraeritrocitario in un gruppo di studenti liceali selezionati in base all'anamnesi familiare.