title: A computer algorithm for differentiating valid from distorted pulse oximeter waveforms in neonates.
abstract: Current pulse oximeter technology is fraught with a significant false alarm rate. This is mainly due to motion artifacts at the sensor site which distort the pulse waveform and render the computation of SaO2 invalid. If the pulse waveform could be automatically recognized as either normal or distorted, then only valid SaO2 values would be displayed. We observed that the systolic upstroke time (Sy) of the pulse waveform has a narrow and consistent range in normal appearing pulses. The systolic upstroke time (Sy) is the time from the onset of systole to the peak of the pulse waveform. Comparison of a preset range of Sy was made against Sy obtained by computer analysis of each pulse waveform. Visual examination of 14,090 pulses was carried out to determine the sensitivity and false positive rate of the algorithm. Sensitivity of computer detection of valid pulses was 92% with a positive predictive value of 92%. When used on line for continuous recording of SaO2 in patients, this simple algorithm has the potential to decrease the false alarm rate of pulse oximeters and improve the accuracy of long-term SaO2 recordings.
authors.affiliation: Division of Neonatology, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Adams
authors.forename: I M
authors.initials: IM
authors.lastname: Inman
authors.forename: S A
authors.initials: SA
authors.lastname: Abreu
authors.forename: I A
authors.initials: IA
authors.lastname: Zabaleta
authors.forename: M A
authors.initials: MA
authors.lastname: Sackner
mesh_terms: D000465:Algorithms; D001049:Apnea / Q000175:diagnosis*; D001330:Electronic Data Processing / Q000379:methods; D005189:False Positive Reactions; D006801:Humans; D007231:Infant, Newborn; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D010092:Oximetry / Q000295:instrumentation / Q000379:methods*; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D010100:Oxygen