[Prognostic value of neuroendocrine activation after acute myocardial infarction].
Complex neurohumoral activation is associated with acute myocardial infarction. Either as a cause of adverse events or as a marker of haemodynamic status, augmented neurohumoral activation is associated with decreased short- and long-term survival. Although the predictive value of neurohumoral assessment is generally reduced after adjustment for demographic, clinical and haemodynamic variables in multivariate models, recent data suggest that determination of circulating neurohormone concentrations may provide significant, independent prognostic information in cases of acute myocardial infarction. The clinical usefulness of neurohumoral determination as a risk stratification tool and as a method of identifying patients who might benefit from therapeutic intervention remains to be established.
Omland
T
T
Medisinsk Avdeling, Sentralsjukehuset i Rogaland, Universitetet i Bergen.
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage; D009320:Atrial Natriuretic Factor / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism; D016232:Endothelins / Q000378:metabolism; D006801:Humans; D009203:Myocardial Infarction / Q000378:metabolism / Q000401:mortality* / Q000503:physiopathology; D011379:Prognosis; D012084:Renin-Angiotensin System / Q000187:drug effects
D000806:Angiotensin-Converting Enzyme Inhibitors; D002395:Catecholamines; D016232:Endothelins; D009320:Atrial Natriuretic Factor
Prognostisk verdi av neuroendokrin aktivering etter akutt hjerteinfarkt.