Antiulcer activity of Pteleopsis suberosa.
The bark Pteleopsis suberosa is commonly used in Mali for the treatment of gastric ulcers. The present study evaluated the antiulcerogenic property of chloroform, ethanol and aqueous extracts and of decoction of P. suberosa bark against ulcer lesions induced by ethanol and indomethacin in rats. The results tend to confirm the popular use of the plant.
De Pasquale
R
R
Pharmaco-Biological Department, School of Pharmacy, University of Messina, Italy.
Germanò
M P
MP
Keita
A
A
Sanogo
R
R
Iauk
L
L
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D000431:Ethanol / Q000633:toxicity; D007213:Indomethacin / Q000633:toxicity; D008297:Male; D008519:Medicine, Traditional; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017207:Rats, Sprague-Dawley; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy*; D013729:Terpenes / Q000494:pharmacology / Q000627:therapeutic use
D000897:Anti-Ulcer Agents; D010936:Plant Extracts; D013729:Terpenes; D000431:Ethanol; D007213:Indomethacin