Bronchiolitis obliterans organizing pneumonia associated with minocycline therapy: a possible cause.
We report the case of a woman who presented with dyspnoea whilst taking minocycline for acne. Imaging features of bilateral patchy alveolar opacities suggested a diagnosis of bronchiolitis obliterans organizing pneumonia, which was confirmed by lung biopsy. The patient improved, partially, after stopping minocycline, and then completely on treatment with corticosteroids, without relapse when these where stopped 8 weeks later.
Piperno
D
D
Service de Pneumologie, Université Claude Bernard, Lyon, France.
Donné
C
C
Loire
R
R
Cordier
J F
JF
D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008911:Minocycline / Q000009:adverse effects* / Q000627:therapeutic use; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D008911:Minocycline