The challenge of fetal gene therapy.
Three recent reports describe the first in vivo attempts at fetal gene therapy. The results underline the need for more intensive studies of the scientific and ethical implications of this new and perhaps more preventive approach to gene therapy.
Coutelle
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Department of Biochemistry and Molecular Genetics, St. Mary's Hospital Medical School, Imperial College, London, UK.
Douar
A M
AM
Colledge
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Froster
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D000818:Animals; D004195:Disease Models, Animal; D004992:Ethics, Medical; D005260:Female; D005315:Fetal Diseases / Q000235:genetics / Q000628:therapy*; D017930:Genes, Reporter; D015316:Genetic Therapy / Q000592:standards; D005822:Genetic Vectors; D005854:Germ Cells; D006801:Humans; D008168:Lung / Q000196:embryology; D008431:Maternal-Fetal Exchange; D051379:Mice; D011247:Pregnancy; D012756:Sheep / Q000196:embryology