title: [Hepatosplenic angiosarcoma complicated by hemoperitoneum and disseminated intravascular coagulation. Treatment by arterial embolization and chemotherapy].
abstract: We report a case of hepatic and splenic angiosarcoma in a 34 year-old man presenting with hemoperitoneum and consumption coagulopathy. Histological and immunohistological diagnosis was based on a biopsy specimen obtained through the transjugular route. Embolization via the splenic artery for the most significant lesions and intravenous chemotherapy resulted in a partial response in the liver and splenic tumour masses and survival with a good quality of life. The initial complications recurred after chemotherapy was stopped and death occurred after 15 months. The benefit of arterial embolization and chemotherapy in this rare and usually rapidly fatal disease should be assessed in other patients.
authors.affiliation: Unité d'Hêpato-Gastroentérologie, Centre Hospitalier Intercommunal, Poissy.
authors.forename: R
authors.initials: R
authors.lastname: Tordjman
authors.forename: C
authors.initials: C
authors.lastname: Eugène
authors.forename: O
authors.initials: O
authors.lastname: Clouet
authors.forename: L
authors.initials: L
authors.lastname: Wesenfelder
authors.forename: C
authors.initials: C
authors.lastname: Collet
authors.forename: A
authors.initials: A
authors.lastname: Bergue
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000628:therapy; D004621:Embolization, Therapeutic / Q000379:methods; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D006465:Hemoperitoneum / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D008297:Male; D012008:Recurrence; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D014057:Tomography, X-Ray Computed
vernacular_title: Angiosarcome hépato-splénique compliqué d'hémopéritoine et de coagulation intravasculaire disséminée. Traitement par embolisation artérielle et chimiothérapie.