[Dysphonia produced by corticoid inhalation: truth or myth?].
One of the undesirable side-effects usually related to the administration of inhaled corticoids is the development of dysphonia. This association has been attributed to the effect of the corticoid on vocal muscles. We present 5 asthma patients who all developed dysphonia at some time. All were examined by video laryngostroboscope. Abundant mucus on the vocal cords was observed in 4 patients, and small vocal nodules as well as mucus was seen in 2. We believe that dysphonia is transitory in these patients and is related to the presence of mucus that prevents correct closure of the glottis. Corticoids are not only not contraindicated in such cases, but their continued use would also benefit the condition of dysphonia as asthmatic inflammation improves.
Bonet Agustí
M
M
Universidad de Barcelona.
Casan Clarà
P
P
D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D002648:Child; D005260:Female; D005931:Glottis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000187:drug effects; D014832:Voice Disorders / Q000139:chemically induced* / Q000175:diagnosis
D000305:Adrenal Cortex Hormones
Disfonía producida por corticoides en inhalación: verdad o mito?