Intraoperative monitoring of cerebral blood flow during ventricular shunting in hydrocephalic pediatric patients.
Several studies have demonstrated lowered cerebral blood flow (CBF) in patients with hydrocephalus and symptoms of raised intracranial pressure. Ventricular shunting in such cases permits a sudden increase in CBF. The pathophysiology of functional brain deficit secondary to hydrocephalus is little understood. Improvement of the patient's clinical status after drainage of CSF suggests that cerebral dysfunction is not necessarily due to permanent brain damage. In fact, it improves rapidly after ventricular taps. In view of this it would be helpful to monitor cerebral perfusion. The transcranial Doppler (TCD) ultrasonography technique allows real-time monitoring of the intracranial circulation and makes it possible to evaluate the physiopathological correlation between ventricular dilatation and CBF. Continuous monitoring of the middle cerebral artery (MCA) by TCD was performed in three hydrocephalic children (2 months, 14 months, and 8 years old) during a ventricular-peritoneal shunt operative procedure. A TC-2000S device provided by an IMP-F fixed probe was utilized. In all patients, when the lateral ventricle was shunted and the CSF could flow away, a clear and sudden increase of flow velocity above 30% was detected. The pulsatility index (PI) was also pathologically increased in all patients. A gradual normalization of this index was revealed after the shunting procedure. Our experience has to be considered preliminary, but nonetheless, it suggests a clear correlation between hydrocephalic disease and concomitant CBF alterations.(ABSTRACT TRUNCATED AT 250 WORDS)
Iacopino
D G
DG
Sezione di Neurochirurgia Infantile, Policinico Universitario, Messina, Italy.
Zaccone
C
C
Molina
D
D
Todaro
C
C
Tomasello
F
F
Cardia
E
E
D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology*; D002648:Child; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D007223:Infant; D007427:Intracranial Pressure; D008297:Male; D016343:Monitoring, Intraoperative / Q000295:instrumentation*; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation*; D017287:Ventriculoperitoneal Shunt