Toxicity and immunologic effects of in vivo retrovirus-mediated gene transfer of the herpes simplex-thymidine kinase gene into solid tumors.
Culver
K W
KW
Human Gene Therapy Research Institute, Iowa Methodist Medical Center, Des Moines 50309, USA.
Moorman
D W
DW
Muldoon
R R
RR
Paulsen
R M
RM
Lamsam
J L
JL
Walling
H W
HW
Link
C J
CJ
D000212:Acyclovir / Q000627:therapeutic use; D000818:Animals; D004351:Drug Resistance / Q000235:genetics; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D005822:Genetic Vectors; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D009369:Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D012190:Retroviridae / Q000235:genetics; D018139:Simplexvirus / Q000201:enzymology* / Q000235:genetics*; D013937:Thymidine Kinase / Q000235:genetics*; D014407:Tumor Cells, Cultured
D013937:Thymidine Kinase; D015774:Ganciclovir; D000212:Acyclovir