[Study of anti-cerebral thromboembolism injection's activity on experimental arterial thrombosis and its therapeutical mechanism].
Anti-Cerebral Thromboembolism Injection (ACTI), applied intravenously in Cattaneo's animal model of arterial thrombosis, could significantly reduce the weight of thrombus, blood viscosities, plasma TXB2 level and delay the prothrombin time, compared to control group (P < 0.05). From this trial, it was indicated that ACTI's reducing thrombosis action was the result of inhibiting aggregation and releasing of platelets through reducing whole blood viscosities and TXB2 level.
Liu
X H
XH
Dongzhimen Hospital, Beijing University of TCM.
Ren
Y
Y
Song
C S
CS
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D005343:Fibrinolytic Agents / Q000494:pharmacology*; D008297:Male; D011517:Prothrombin Time; D011817:Rabbits; D013927:Thrombosis / Q000097:blood / Q000517:prevention & control*; D013929:Thromboxane B2 / Q000097:blood
D004365:Drugs, Chinese Herbal; D005343:Fibrinolytic Agents; D013929:Thromboxane B2