[The efficacy of several kinds of treatment for advanced hepatocellular carcinoma--a report of an over-five-year survivor by regional and systemic chemotherapy and adjuvant surgery].
We encountered a 53-year-old male patient with advanced hepatocellular carcinoma (HCC) uncontrolled by transcatheter arterial embolization (TAE). Numerous tumors with a huge one occupying the lateral segment were shown on abdominal ultrasonogram, computed tomogram and angiogram. The first TAE was ineffective for the lesions because of the development of collateral feeders. Lateral segmentectomy and, "wrapping therapy" for the liver remnant were performed, and catheters were put both into the hepatic artery and into the portal vein for regional chemotherapy. About a year after the procedure, anticancer drugs were administered. When tumor stains were found by following computed tomography or angiography, TAE was performed. The patient has survived for five years and four months. The combination of several kinds of treatment serves to improve the prognosis of patients with advanced HCC if the liver function is preserved.
Aono
Y
Y
Dept. of Surgery, Center for Adult Diseases, Osaka.
Sasaki
Y
Y
Imaoka
S
S
Nakano
H
H
Furukawa
H
H
Ishikawa
O
O
Kabuto
T
T
Kameyama
M
M
Hiratsuka
M
M
Ohigashi
H
H
D000970:Antineoplastic Agents / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017741:Survivors
D000970:Antineoplastic Agents; D007459:Iodized Oil; D002945:Cisplatin