Novel potent inhibitors of the DNA repair enzyme poly(ADP-ribose)polymerase (PARP).
Griffin
R J
RJ
Cancer Research Unit, Medical School, University of Newcastle, UK.
Pemberton
L C
LC
Rhodes
D
D
Bleasdale
C
C
Bowman
K
K
Calvert
A H
AH
Curtin
N J
NJ
Durkacz
B W
BW
Newell
D R
DR
Porteous
J K
JK
D000818:Animals; D001583:Benzoxazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D004791:Enzyme Inhibitors; D006801:Humans; D007939:Leukemia L1210; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D001583:Benzoxazoles; D004791:Enzyme Inhibitors; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; D011799:Quinazolines