title: Effect of fermentable fructo-oligosaccharides on mineral, nitrogen and energy digestive balance in the rat.
abstract: In the present study, we have assessed the apparent retention of gross energy, nitrogen and Ca, Mg, Fe, Zn and Cu in rats receiving a diet supplemented with fermentable fructo-oligosaccharides with high and low degree of polymerization. Feeding 10% Raftilose (degree of polymerization: 4.8) or 10% Raftiline (degree of polymerization: 10) decreased to the same extent (a) the fecal excretion of all the minerals, despite an increase in total fecal mass excretion leading to an improvement of the absorption of Ca, Mg, Fe and Zn; (b) total gross energy absorption; and (c) led to an increase in the faecal excretion and to a decreased urinary excretion of nitrogen, suggesting a displacement of part of nitrogen excretion towards the large intestine. Feeding fermentable fructo-oligosaccharides may thus constitute a good way to counteract syndromes resulting from hyperammonemia or disturbed Fe, Ca, Mg and Zn homeostasis.
authors.affiliation: Département des Sciences Pharmaceutiques, Université Catholique de Louvain, Brussels, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: Delzenne
authors.forename: J
authors.initials: J
authors.lastname: Aertssens
authors.forename: H
authors.initials: H
authors.lastname: Verplaetse
authors.forename: M
authors.initials: M
authors.lastname: Roccaro
authors.forename: M
authors.initials: M
authors.lastname: Roberfroid
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D003300:Copper / Q000378:metabolism; D004032:Diet; D004040:Dietary Carbohydrates / Q000378:metabolism*; D004734:Energy Metabolism; D005285:Fermentation; D005630:Fructans / Q000378:metabolism; D005632:Fructose / Q000378:metabolism*; D007501:Iron / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D008297:Male; D008903:Minerals / Q000378:metabolism* / Q000652:urine; D009584:Nitrogen / Q000378:metabolism*; D009844:Oligosaccharides / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D015032:Zinc / Q000378:metabolism
chemical_list: D004040:Dietary Carbohydrates; D005630:Fructans; D008903:Minerals; D009844:Oligosaccharides; D005632:Fructose; D003300:Copper; D007501:Iron; D008274:Magnesium; D015032:Zinc; D009584:Nitrogen; D002118:Calcium