Expression of myelin proteolipid protein in oligodendrocytes and transfected cells.
The data presented in this paper show that the appropriate tools are now available to study the behavior of PLP and DM20 transcripts engineered with either point mutations or deletion of specific domains. Such studies should begin to provide new insights into the functions of PLP and DM20 and their role in relation to the optimal functioning of the nervous system.
Lees
M B
MB
Department of Biomedical Sciences, E.K. Shriver Center, Waltham, MA 02254, USA.
Smith
F I
FI
Dyer
C A
CA
Greer
J M
JM
Pakaski
M
M
D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D005455:Fluorescent Antibody Technique; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D008969:Molecular Sequence Data; D018991:Myelin Proteolipid Protein / Q000096:biosynthesis* / Q000737:chemistry / Q000502:physiology; D009836:Oligodendroglia / Q000378:metabolism*; D013194:Staining and Labeling; D013329:Structure-Activity Relationship; D014162:Transfection; D014407:Tumor Cells, Cultured
D018991:Myelin Proteolipid Protein