title: Home-use tooth bleaching agents: an in vitro study on quantitative effects on enamel, dentin, and cementum.
abstract: Studies on home-use bleaching agents containing carbamide or hydrogen peroxide demonstrate minimal topographic alteration and insignificant organic change to tooth material. This in vitro study evaluated the effects of a three-step commercial home-use bleaching agent on extracted human incisors over time. Each tooth was digitized by baseline and sequential profilometry and analyzed using computer software. Statistically significant volume loss was evident in cementum and dentin after simulations of 4 and 8 weeks of use.
authors.affiliation: University of Michigan, School of Dentistry, Ann Arbor 48109, USA.
authors.forename: A
authors.initials: A
authors.lastname: Wandera
authors.forename: R J
authors.initials: RJ
authors.lastname: Feigal
authors.forename: W H
authors.initials: WH
authors.lastname: Douglas
authors.forename: M R
authors.initials: MR
authors.lastname: Pintado
mesh_terms: D002951:Citrates / Q000009:adverse effects; D019343:Citric Acid; D003739:Dental Cementum / Q000187:drug effects*; D003742:Dental Devices, Home Care / Q000009:adverse effects; D003743:Dental Enamel / Q000187:drug effects*; D003804:Dentin / Q000187:drug effects*; D005069:Evaluation Studies as Topic; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects*; D007091:Image Processing, Computer-Assisted; D018709:Statistics, Nonparametric; D013997:Time Factors; D014025:Titanium / Q000009:adverse effects; D014073:Tooth Bleaching / Q000009:adverse effects* / Q000379:methods
chemical_list: D002951:Citrates; C009495:titanium dioxide; D019343:Citric Acid; D006861:Hydrogen Peroxide; D014025:Titanium