title: [Optimal use of non opioid analgesics].
abstract: This review describes the mechanisms of analgesic effect, advantages and risks related to the perioperative use of non steroidal antiinflammatory drugs (NSAID's). The NSAID's should be used as the first analgesic, around the clock, with a rapid onset of the therapy. Their combination with other NSAID's (acetaminophen) or opioids can have an additive analgesic effect and may limit frequent secondary effects as nausea and vomiting. Their potential toxicity must be remembered and the contra indications, maximum doses and duration of treatment have to be respected.
authors.affiliation: Département d'Anesthésie-Réanimation de l'Hôpital Bicêtre.
authors.forename: D
authors.initials: D
authors.lastname: Fletcher
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use*; D000556:Ambulatory Surgical Procedures; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D009420:Nervous System / Q000187:drug effects; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000082:Acetaminophen
vernacular_title: Optimisation de l'utilisation des analgésiques non morphiniques.