title: [Ultrastructural findings in pleural cysts in spontaneous pneumothorax].
abstract: Lung biopsies obtained by conventional thoracotomy from five patients (mean age 33.6 years, range 21-45) following recurrence of spontaneous pneumothorax were studied by light, scanning, and transmission electron microscopy. The purpose of the study was to define abnormalities that predispose to air penetration through the intact wall of pleural blebs. Two types of blebs were identified either with a complete or with an incomplete layer of mesothelial cells. In those areas where the mesothelial cells were lacking, the walls only consisted of irregular, discontinuous collagen fibers. Increasing intraalveolar pressure may distort the net of collagen fibers and air penetration appears to be possible. The wall of pleural blebs is generally weakened by degenerative changes and may predispose to recurrence of pneumothorax. Therefore, wedge resection of the blebs including the underlying lung parenchyma is suggested for surgical therapy of pneumothorax.
authors.affiliation: Abteilung Chirurgie, Bundeswehrkrankenhauses Ulm.
authors.forename: H P
authors.initials: HP
authors.lastname: Becker
authors.forename: I
authors.initials: I
authors.lastname: Schmitz
authors.forename: J
authors.initials: J
authors.lastname: Radomsky
authors.forename: K M
authors.initials: KM
authors.lastname: Müller
mesh_terms: D000328:Adult; D001706:Biopsy; D003094:Collagen / Q000648:ultrastructure; D003560:Cysts / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010994:Pleura / Q000473:pathology; D010995:Pleural Diseases / Q000473:pathology* / Q000601:surgery; D011030:Pneumothorax / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D013908:Thoracotomy
chemical_list: D003094:Collagen
vernacular_title: Ultrastrukturelle Befunde pleuraler Cysten beim Spontanpneumothorax.