Cranial arteriopathy in familial Vogt-Koyanagi-Harada syndrome.
A 59-year-old woman with Vogt-Koyanagi-Harada (VKH) syndrome presented with transient ischemic attacks. Magnetic resonance angiography showed multiple areas of stenosis affecting the intracranial portions of both internal carotid arteries. Conventional angiography confirmed these abnormalities and also demonstrated tapering stenosis of the extracranial segment of the left internal carotid artery. This patient and her similarly affected daughter represent the first reported association between cranial arteriopathy and intergenerational passage of VKH syndrome.
Ryan
S J
SJ
Department of Neurology, University of Kentucky, USA.
Pettigrew
L C
LC
D002343:Carotid Artery, Internal / Q000473:pathology; D016893:Carotid Stenosis / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000209:etiology; D018810:Magnetic Resonance Angiography; D008875:Middle Aged; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000235:genetics* / Q000473:pathology