Genetic dissection of inflammatory responses.
Recent advances in classical genetics, molecular biology, and genomics herald a renaissance of genetic analysis of hereditary disease in both humans and animal models. It is increasingly feasible to analyze multifactorial traits both genetically and functionally. These advances parallel research aimed at unravelling the genetic code of humans and model species. Only the integration of these two approaches will secure the functionally significant conclusion of the genomic exercise.
Nadeau
J H
JH
Centre for the Study of Host Resistance, Montreal General Hospital, McGill University, Quebec, Canada.
Arbuckle
L D
LD
Skamene
E
E
D000818:Animals; D004195:Disease Models, Animal; D020022:Genetic Predisposition to Disease; D006801:Humans; D007249:Inflammation / Q000235:genetics*; D051379:Mice; D008815:Mice, Inbred Strains; D009163:Mycobacterium bovis / Q000235:genetics