Serous psammocarcinoma of the ovary in an adolescent female.
A rare form of epithelial ovarian carcinoma in an adolescent female is reported. Serous psammocarcinoma is a type of ovarian cancer that is characterized by extensive psammoma body formation and has not been reported in this age group. Histopathologically, this tumor exhibits stromal invasion, vascular invasion, epithelial cells with low to moderate nuclear atypia, nests of solid epithelial cells less than 15 cells in diameter, and psammoma bodies that involve at least 75% of papillae or nests of cells. The patient underwent optimal surgical debulking and nine courses of adjuvant chemotherapy with carboplatinum and cyclophosphamide and is currently disease free. The prognosis for this type of ovarian cancer is unclear, but it appears to be better than other forms of epithelial ovarian cancer.
Kelley
J L
JL
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh Medical Center, Magee-Womens Hospital, Pennsylvania 15213, USA.
Capelle
S C
SC
Kanbour-Shakir
A
A
D000293:Adolescent; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*