title: [Treatment of pleural tuberculosis with a short 4-month regimen: preliminary results].
abstract: The aim of this prospective study was to evaluate the results of a four-month regimen (2HRZ/2HR) in the treatment of isolated tuberculous pleurisy with effusion. It included 68 patients presenting with histologically confirmed tuberculous pleurisy treated with 2HRZ/2HR, physiotherapy and aspiration of the pleura. Patients were seen every 2 months during treatment, and then 1, 3, 4, 6, 12, and 24 months after the end of treatment. Preliminary results show a favourable response in 58 patients (85%) and minimal pleural thickening in 10 patients. There were no failures, no relapses nor any extrapleural dissemination after a follow-up period of on average 20 months. These encouraging results need to be evaluated in a long-term study.
authors.affiliation: Service de Pneumologie, Hôpital du 20 Août, Casablanca, Maroc.
authors.forename: Z
authors.initials: Z
authors.lastname: Bouayad
authors.forename: A
authors.initials: A
authors.lastname: Aichane
authors.forename: N
authors.initials: N
authors.lastname: Trombati
authors.forename: S
authors.initials: S
authors.lastname: Amrani
authors.forename: A
authors.initials: A
authors.lastname: Bahlaoui
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D011446:Prospective Studies; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D014396:Tuberculosis, Pleural / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin
vernacular_title: Traitement de la tuberculose pleurale par un régime court de 4 mois: résultats préliminaires.