title: Primary signet ring cell carcinoma of the urinary bladder. Review of the literature and report of two cases.
abstract: The signet ring cell carcinoma of the urinary bladder is a rare neoplasm; the 70 cases found in the literature pursued a fulminant and mostly fatal course; the neoplasms diffusely invaded the bladder wall without forming intraluminal growths and could not be controlled by segmental resection, radiotherapy and chemotherapy alone or in combination. We herewith present 2 cases of primary signet ring cell carcinoma of the urinary bladder--one associated with high-grade transitional cell carcinoma and in situ carcinoma--and review the literature.
authors.affiliation: Department of Urology, Istanbul Faculty of Medicine, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Erdoğru
authors.forename: I
authors.initials: I
authors.lastname: Kiliçaslan
authors.forename: T
authors.initials: T
authors.lastname: Esen
authors.forename: H
authors.initials: H
authors.lastname: Ander
authors.forename: O
authors.initials: O
authors.lastname: Ziylan
authors.forename: V
authors.initials: V
authors.lastname: Uysal
mesh_terms: D002278:Carcinoma in Situ / Q000473:pathology; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000473:pathology