title: Effect of blood transfusion on tumor recurrence and postoperative pharyngocutaneous fistula formation in patients subjected to total laryngectomy.
abstract: Some surgical oncologists and otolaryngologists have reported that transfusion-induced immunosuppression may increase the incidence of recurrence and infectious complications in patients subjected to head and neck surgery for carcinoma. The relationship between intra-operative blood transfusion and postoperative pharyngocutaneous fistula formation and/or tumor recurrence is controversial. In a retrospective study of 110 total laryngectomized patients, we found no statistically significant differences between the transfused and nontransfused groups in terms of tumor recurrence and fistula formation.
authors.affiliation: Ear, Nose and Throat Department, Ankara Numune Hospital, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Celikkanat
authors.forename: C
authors.initials: C
authors.lastname: Koç
authors.forename: M U
authors.initials: MU
authors.lastname: Akyol
authors.forename: C
authors.initials: C
authors.lastname: Ozdem
mesh_terms: D000328:Adult; D000368:Aged; D001803:Blood Transfusion; D017577:Cutaneous Fistula / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery* / Q000628:therapy*; D007825:Laryngectomy; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010614:Pharynx / Q000503:physiopathology*; D012189:Retrospective Studies