[The cerebral blood circulation during hypokinesia under the influence of hypercapnia, hypotonia, GABA and neurosensory stimulation].
We studied the formation of vasomotor reflexes in hypokinesia and responses of the brain vessels to the action of GABA, hypotension, and hypercapnia. We found that the response of the brain vessels to GABA is delayed and the mechanisms which supported an adequate cerebral vasculation are distorted in hypotension. At the same time the disturbance of the reflectory reaction of the brain vessels in the course of forming the vasomotor reflexes and the absence of significant changes in response to GABA were noticed. The capability of GABA of inhibiting cerebral blood circulation arising in hypokinesia is shown.
Akopian
V P
VP
Kocharian
A Zh
AZh
Topchian
A V
AV
Mirzoian
N R
NR
D000818:Animals; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000502:physiology*; D004558:Electric Stimulation; D005267:Femoral Nerve; D006935:Hypercapnia / Q000503:physiopathology*; D018476:Hypokinesia / Q000503:physiopathology*; D007022:Hypotension / Q000139:chemically induced / Q000503:physiopathology*; D011817:Rabbits; D051381:Rats; D012149:Restraint, Physical; D013997:Time Factors; D014294:Trimethaphan; D014665:Vasodilator Agents; D014666:Vasomotor System / Q000187:drug effects / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D014665:Vasodilator Agents; D005680:gamma-Aminobutyric Acid; D014294:Trimethaphan; C017774:trimethaphan camsylate
Mozgovoe krovoobrashchenie v usloviiakh gipokinezii pod vliianiem giperkapnii, gipotonii, GAMK i neĭrosensornog razdrazheniia.