title: A felodipine-metoprolol extended-release tablet: its properties and clinical development.
abstract: The current failure of antihypertensive therapy to control BP in many hypertensive patients highlights the need for new treatment strategies. Ideally, these new strategies should provide reliable, effective 24 h BP control in all types of patients with a convenient, well-tolerated regimen. Logimax, an extended-release tablet containing felodipine and metoprolol, has been developed, which provides more effective control of BP in a wider range of patients than either component as monotherapy, without compromising tolerability. This combination increases the likelihood of achieving target BP and is therefore likely to provide further reductions in cardiovascular risk.
authors.affiliation: Department of Medicine, Ostra Hospital, Gothenburg, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Dahlöf
authors.forename: O K
authors.initials: OK
authors.lastname: Andersson
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D015736:Felodipine / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008790:Metoprolol / Q000627:therapeutic use*; D013607:Tablets
chemical_list: D000959:Antihypertensive Agents; D003692:Delayed-Action Preparations; D013607:Tablets; D008790:Metoprolol; D015736:Felodipine