Phenotype differences of STRs in 7 human populations.
A maximum of 6 STR systems (TH01, VWA, ACTBP2, FES, F13B, D21S11) was investigated in 7 human populations (Germans, Turks, Moroccans, Japanese, Chinese, Papuans, Ovambos). In each population no deviations from Hardy-Weinberg equilibrium were observed. Out of each population the phenotypes of 50 individuals (comprising 3 to 6 STRs) were randomly selected. Based on the phenotype frequencies interpopulation comparisons were carried out using the frequencies of each other population. Within major ethnic groups only minor differences in phenotype frequencies were found. Between major ethnic groups differences of up to several orders of magnitude could be observed. The most discriminative STRs for interpopulation comparisons were TH01, FES and F13B.
Meyer
E
E
Institute of Legal Medicine, Westfälische Wilhelms-Universität, Münster, Germany.
Wiegand
P
P
Brinkmann
B
B
D002681:China; D004247:DNA / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics*; D005858:Germany; D006801:Humans; D007564:Japan; D009018:Morocco / Q000208:ethnology; D009276:Namibia; D010219:Papua New Guinea; D010641:Phenotype; D011110:Polymorphism, Genetic; D044469:Racial Groups / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D014421:Turkey
D004247:DNA