title: [Indications of penetrating keratoplasty from a histopathological study of 1129 corneal buttons (from 1982 to 1991)].
abstract: OBJECTIVE
  To analyze the indications or the penetrating keratoplasties which were conducted in the Bordeaux University Hospital over the 1982-1991 period and to compare these findings with those of previously published studies.
  
  
  METHODS
  The histopathological study of 1129 corneal buttons was analyzed according to conventional methods in the Histopathology Department Pellegrin Hospital.
  
  
  RESULTS
  The main indications for penetrating keratoplasty were (in decreasing order of frequency): pseudophakic or aphakic corneal oedema (28.7%), keratoconus (12.1%), regrafts (11.1%), and corneal scars (10.7%). Less frequent indications for penetrating keratoplasty included Fuchs' endothelial dystrophy (7.8%); corneal trauma (7.3%) and herpes (7.2%). Ophthalmological conditions requiring penetrating keratoplasty fall into six groups of unequal size: 1) corneal oedema (28.7%); 2) keratitis (26%); 3) dystrophies (23.2%); 4) graft failures (11.1%); 5) trauma and chemical burns (8%) and 6) miscellaneous (2.9%).
  
  
  CONCLUSIONS
  The authors emphasize the importance of studying histologically the corneal buttons after penetrating keratoplasty. Corneal oedema after cataract surgery is shown, based on the data presented, to be the main indication for penetrating keratoplasty.
authors.affiliation: Département d'Anatomie Pathologique, Groupe Hospitalier Pellegrin, Bordeaux.
authors.forename: F
authors.initials: F
authors.lastname: Leger
authors.forename: P A
authors.initials: PA
authors.lastname: Ndiaye
authors.forename: W
authors.initials: W
authors.lastname: Williamson
authors.forename: F
authors.initials: F
authors.lastname: Lagoutte
authors.forename: I
authors.initials: I
authors.lastname: Riss
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D015948:Keratoplasty, Penetrating / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged
vernacular_title: Indications de la kératoplastie transfixiante à partir d'une étude histopathologique de 1 129 boutons cornéens (de 1982 à 1991).