Transferability of blood lead determinations by furnace atomic absorption spectrophotometry and continuum background correction.
We have examined and proved feasible the transfer of a method for blood lead determination, developed and optimized for a Zeeman-corrected instrument, to a continuum-corrected furnace atomic absorption spectrophotometer. Numerous reference materials analyzed with the continuum-corrected instrument gave results within 10 micrograms/L (0.05 mumol/L) at low values and varied by < 6% at values > 200 micrograms/L (0.97 mumol/L). Forty-four routine human blood specimens were analyzed by the same method with both continuum- and Zeeman-corrected instrumentation, and gave results that agreed within about the same limits as found with reference materials. The day-to-day precision was about 1/5 the accuracy results. The detection limit was approximately 5 micrograms/L (0.025 mumol/L).
Qiao
H
H
Wadsworth Center, New York State Department of Health, Albany, NY 12201, USA.
Parsons
P J
PJ
Slavin
W
W
D006801:Humans; D007854:Lead / Q000097:blood*; D011786:Quality Control; D012015:Reference Standards; D012680:Sensitivity and Specificity; D013054:Spectrophotometry, Atomic / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data
D007854:Lead