title: Haemoglobin engineering. For fun and money.
abstract: The recent transplantation of an unusual allosteric effect from crocodile to human haemoglobin has implications for both molecular evolution and the engineering of artificial blood substitutes.
authors.affiliation: Department of Biochemical Sciences A. Rossi Fanelli, University of Rome La Sapienza, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Brunori
authors.forename: F
authors.initials: F
authors.lastname: Cutruzzolà
authors.forename: B
authors.initials: B
authors.lastname: Vallone
mesh_terms: D000489:Alligators and Crocodiles; D000494:Allosteric Regulation; D000818:Animals; D005075:Biological Evolution; D001802:Blood Substitutes / Q000737:chemistry; D005818:Genetic Engineering; D006454:Hemoglobins / Q000737:chemistry / Q000235:genetics; D006801:Humans; D015394:Molecular Structure
chemical_list: D001802:Blood Substitutes; D006454:Hemoglobins