title: Dietary fats and blood pressure.
abstract: This chapter reviews the evidence from epidemiologic studies and controlled clinical trials dealing with dietary fats and blood pressure. Trials studying the effect on blood pressure of n-3 polyunsaturated fatty acids from fish oil show a dose-response hypotensive effect that may be restricted to patients with atherosclerotic cardiovascular disease. However, fish oil is not a practical therapy for hypertension given the large dose required (10 capsules per day) for a small effect (3-4 mmHg). From numerous studies, it is clear that saturated and n-6 polyunsaturated fats have no effect on blood pressure. Monounsaturated fats also have no effect but fewer studies have examined this relation.
authors.affiliation: Rush Institute on Aging, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Morris
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D003430:Cross-Sectional Studies; D004041:Dietary Fats; D005227:Fatty Acids / Q000494:pharmacology; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology; D006801:Humans; D011446:Prospective Studies
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D015525:Fatty Acids, Omega-3