title: Nicotine gum and self-help behavioral treatment for smoking relapse prevention: results from a trial using population-based recruitment.
abstract: Smokers aged 18 to 65 years (N = 1,044) who were able to quit for 24 hr were randomized using a 2 x 2 factorial design to compare nicotine gum to no gum use and self-help materials to no use of materials. All participants were offered a $100 incentive to quit and stay quit for 6 months. Six-month abstinence was 27% in the gum groups, compared with 19% in the no-gum group (p = .002). Compared with the no-gum group, relapse occurred at a significantly lower rate in the gum group for the entire 12 months of follow-up (odds of relapse in the gum group was 0.72, 95% confidence interval, 0.62 to 0.83). There was no significant main effect for the self-help materials, no interaction between gum and materials, and no evidence that the effectiveness of gum differed between the sexes or between heavy and light smokers. Nicotine gum is an effective adjunct to minimal-contact smoking cessation materials plus monetary incentive in a population-based sample of smokers.
authors.affiliation: Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Fortmann
authors.forename: J D
authors.initials: JD
authors.lastname: Killen
mesh_terms: D000328:Adult; D001521:Behavior Therapy; D002638:Chewing Gum; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007389:Internal-External Control; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009538:Nicotine / Q000008:administration & dosage*; D012008:Recurrence; D012648:Self Care / Q000523:psychology*; D012907:Smoking / Q000523:psychology; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D000074606:Smoking Prevention; D016896:Treatment Outcome
chemical_list: D002638:Chewing Gum; D009538:Nicotine