title: [Advanced gastric carcinoma with extensive lymph node metastases successfully treated by sequential methotrexate/5-fluorouracil therapy].
abstract: A 62-year-old man having advanced gastric carcinoma with extended lymph node metastases was successfully treated by a palliative gastrectomy and 6 courses of sequential methotrexate/5-fluorouracil therapy. No side effects were observed, and all enlarged abdominal lymph nodes disappeared. The complete response has continued for 11 months after the initial treatment.
authors.affiliation: Dept. of Gastroenterology, Saiseikai Yahata General Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
authors.forename: A
authors.initials: A
authors.lastname: Matsukuma
authors.forename: I
authors.initials: I
authors.lastname: Sakino
authors.forename: J
authors.initials: J
authors.lastname: Konishi
authors.forename: S
authors.initials: S
authors.lastname: Funahashi
authors.forename: R
authors.initials: R
authors.lastname: Yo
authors.forename: Y
authors.initials: Y
authors.lastname: Iso
authors.forename: K
authors.initials: K
authors.lastname: Ayabe
authors.forename: M
authors.initials: M
authors.lastname: Moriyama
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery
chemical_list: D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate