title: [Spherulocytosis (myospherulosis) of the paranasal sinuses].
abstract: Spherulocytosis (myospherulosis is a disease resulting from the physical emulsion phenomenon between lipid-containing materials and blood. It can be caused by the application of lipid-based ointments with or without antibiotics to wounds. This "foreign-body" reaction appears as a granulation tissue that will cause symptomatic when developing under closed wounds or in such cavities as the middle ear or paranasal sinuses. Poor healing after paranasal sinus surgery may be due to spherulocytosis. This occurred in several cases managed at the University Hospital in Kiel as the result of postoperative nasal packs sensitizing sinus mucosa. These experiences led the authors to conclude the nasal ointment packs should be avoided in paranasal sinus surgery.
authors.affiliation: Klinik für Hals-, Nasen-, Ohrenheilkunde, Universität Kiel.
authors.forename: G S
authors.initials: GS
authors.lastname: Godbersen
authors.forename: J
authors.initials: J
authors.lastname: Kleeberg
authors.forename: J
authors.initials: J
authors.lastname: Lüttges
authors.forename: J A
authors.initials: JA
authors.lastname: Werner
mesh_terms: D000328:Adult; D005549:Foreign-Body Reaction / Q000473:pathology* / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments / Q000009:adverse effects; D010254:Paranasal Sinus Diseases / Q000473:pathology* / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology* / Q000517:prevention & control; D014945:Wound Healing / Q000502:physiology
chemical_list: D009824:Ointments