title: Dietary sodium restriction in the prophylaxis of hypertensive disorders of pregnancy: effects on the intake of other nutrients.
abstract: Dietary sodium restriction is used in the Netherlands in the prophylaxis of preeclampsia. To study the effects of long-term sodium restriction on the intake of other nutrients and the outcome of pregnancy, 68 healthy nulliparous pregnant women were randomly assigned to either a low-sodium diet (20 mmol/24 h) or an unrestricted diet. The diet was consumed between week 14 of gestation and delivery. The dietary intakes of energy, fat, protein, carbohydrate, sodium, potassium, and calcium were estimated with the dietary-history technique. A low-sodium diet reduced the intake of protein (by approximately 15 g/24 h), fat (by 20 g/24 h), and calcium (by 350 mg/24 h) and tended to decrease the energy intake (by approximately 0.7 MJ/24 h). The intakes of carbohydrate and potassium did not differ between the groups. The maternal weight gain was less in the low-sodium group (6.0 +/- 3.7 compared with 11.7 +/- 4.7 kg). Mean birth weight was not significantly different (3.2 +/- 0.5 compared with 3.4 +/- 0.5 kg).
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital Sint Radboud, Nijmegen, Netherlands.
authors.forename: B J
authors.initials: BJ
authors.lastname: van Buul
authors.forename: E A
authors.initials: EA
authors.lastname: Steegers
authors.forename: H W
authors.initials: HW
authors.lastname: Jongsma
authors.forename: A L
authors.initials: AL
authors.lastname: Rijpkema
authors.forename: T K
authors.initials: TK
authors.lastname: Eskes
authors.forename: C M
authors.initials: CM
authors.lastname: Thomas
authors.forename: H
authors.initials: H
authors.lastname: Baadenhuysen
authors.forename: P R
authors.initials: PR
authors.lastname: Hein
mesh_terms: D000328:Adult; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000494:pharmacology; D004039:Diet, Sodium-Restricted; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000494:pharmacology; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology; D004435:Eating / Q000187:drug effects / Q000502:physiology*; D002149:Energy Intake; D005260:Female; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D008137:Longitudinal Studies; D017419:Potassium, Dietary / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control*; D011256:Pregnancy Outcome; D012964:Sodium / Q000097:blood / Q000378:metabolism / Q000652:urine; D015430:Weight Gain / Q000187:drug effects / Q000502:physiology
chemical_list: D002136:Calcium, Dietary; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D017419:Potassium, Dietary; D012964:Sodium