Assignment of the human beta tropomyosin gene (TPM2) to band 9p13 by fluorescence in situ hybridisation.
A sequence tagged site (STS) was developed for the human beta tropomyosin gene (TPM2). The STS was used to amplify DNA from somatic cell hybrids to localise TPM2 to human chromosome 9. Genomic clones isolated with the STS product were in turn used in fluorescence in situ hybridisation to metaphase chromosome spreads to further localise TPM2 to 9p13.
Hunt
C C
CC
Edith Cowan University, Joondalup, Western Australia.
Eyre
H J
HJ
Akkari
P A
PA
Meredith
C
C
Dorosz
S M
SM
Wilton
S D
SD
Callen
D F
DF
Laing
N G
NG
Baker
E
E
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002899:Chromosomes, Human, Pair 9; D017931:DNA Primers; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D016324:Sequence Tagged Sites; D014335:Tropomyosin / Q000235:genetics*
D017931:DNA Primers; C518659:TPM2 protein, human; D014335:Tropomyosin