A case of protracted coxsackie virus meningoencephalitis in a marginally immunodeficient child treated successfully with intravenous immunoglobulin.
A child with acute lymphocytic leukemia who was in clinical remission and developed coxsackie B4 meningoencephalitis is presented. Despite minimal evidence of immunodeficiency, the patient had progression of neurologic disease clinically, electroencephalographically and on laboratory evaluation of spinal fluid. A dramatic response to the use of intravenous immunoglobulins is reported and its rationale explained.
Geller
T J
TJ
M.D. Department of Neurology, St. Louis University School of Medicine, MO 63110, USA.
Condie
D
D
D002675:Child, Preschool; D003384:Coxsackievirus Infections / Q000276:immunology / Q000628:therapy*; D006801:Humans; D016867:Immunocompromised Host; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008590:Meningoencephalitis / Q000276:immunology / Q000628:therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000276:immunology*
D016756:Immunoglobulins, Intravenous