Coal-black hyperpigmentation at birth in a child with congenital adrenal hypoplasia.
Congenital adrenal hypoplasia has been estimated to occur in approximately 1 of 12,500 births. Hyperpigmentation associated with this condition typically appears gradually during a period of months to years. We describe a newborn infant with profound hyperpigmentation in whom adrenal crisis subsequently developed as a result of congenital adrenal hypoplasia.
Jones
D
D
Institute for Molecular Genetics, Baylor College of Medicine, USA.
Kay
M
M
Craigen
W
W
McCabe
E
E
Hawkins
H
H
Dominey
A
A
D000311:Adrenal Glands / Q000002:abnormalities*; D000309:Adrenal Insufficiency / Q000150:complications* / Q000151:congenital / Q000473:pathology; D004817:Epidermis / Q000473:pathology; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology* / Q000473:pathology; D007231:Infant, Newborn; D008297:Male