title: Conservative surgical treatment of renal cell carcinoma. The University of Miami experience.
abstract: Thirty-four patients with renal cell carcinoma underwent renal parenchymal-sparing surgery; 10 enucleation (Group A), 15 partial nephrectomy (Group B), and nine a combination of procedures (Group C). Conservative surgery was performed in the presence of normal contralateral unit in four patients (11.7%). Local recurrence (group A = 1, group B = 2, group C = 2) developed in five patients. Metastases appeared in six patients (17.6%) from 12 to 58 months postoperatively. Adequate renal function was obtained in 32 of the 34 patients. Mean follow-up for all patients was 64.6 months overall, 75.6 months from group A, 64.1 months for group B and 53.4 months for group C. The three and five year probabilities of survival for all patients were 77.8% and 69.5% respectively, 80% for group A, 80% for group B and 85% and 57.1% for group C. Enucleation and partial nephrectomy are both viable options in the management of solitary or bilateral renal cell carcinoma. There is no decline ineffective tumor control and prognosis.
authors.affiliation: Department of Urology, University of Miami School of Medicine, USA.
authors.forename: N L
authors.initials: NL
authors.lastname: Block
authors.forename: G
authors.initials: G
authors.lastname: Ciancio
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D003404:Creatinine / Q000097:blood; D018572:Disease-Free Survival; D005260:Female; D005431:Florida; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000502:physiology; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009392:Nephrectomy / Q000009:adverse effects / Q000379:methods; D011183:Postoperative Complications; D011379:Prognosis; D015996:Survival Rate
chemical_list: D003404:Creatinine