title: The uptake of enflurane during anaesthesia.
abstract: The uptake of enflurane at a constant end-expired concentration of 2% in oxygen was studied in 38 patients, ASA 1 or 2, undergoing elective orthopaedic procedures. The anaesthetic was administered using a computer-controlled closed circle system. Following an initial 4 min period during which the expired concentration of enflurane was established, the rate of uptake of enflurane showed a triexponential decline. The mean cumulative use of enflurane after 60 min was 10.7 ml, and after 120 min was 18.4 ml.
authors.affiliation: Royal Marsden NHS Trust, London.
authors.forename: D
authors.initials: D
authors.lastname: Devchand
authors.forename: M K
authors.initials: MK
authors.lastname: Chakrabarti
authors.forename: G G
authors.initials: GG
authors.lastname: Lockwood
mesh_terms: D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D004737:Enflurane / Q000493:pharmacokinetics*; D006801:Humans; D008838:Microcomputers; D008875:Middle Aged; D008956:Models, Chemical; D013131:Spine / Q000601:surgery; D013997:Time Factors
chemical_list: D004737:Enflurane