title: Hepatic artery resistance before and after standard meal in subjects with diseased and healthy livers.
abstract: OBJECTIVE
  To assess fasting and postprandial resistive index (RI) in subjects with healthy and diseased livers.
  
  
  METHODS
  Subjects with healthy (n = 10) and diseased (n = 33) livers underwent fasting and postprandial Doppler ultrasonography of the hepatic artery. Findings were compared with parameters for liver disease and Child class A-C and Child score of 5-15.
  
  
  RESULTS
  The mean postprandial RI increase in healthy subjects was 42% (all, > or = 20%) and in patients with liver disease was 7% (six, > or = 20%). Patients with class A disease (n = 12) had a significantly greater increase in post-prandial RI (13%) than those with class B or C disease (3%) (P < .05). All patients with class C disease (n = 9) had an increased postprandial RI of less than 10%. The 13 patients with at least 10% increase in postprandial RI had less severe liver disease (Child score, 6.1 +/- 1.3 [standard deviation]) than the 20 patients with less than 10% increase (Child score, 8.4 +/- 1.7) (P < .01).
  
  
  CONCLUSIONS
  A normal marked increase in postprandial RI is generally not seen in patients with severe liver disease.
authors.affiliation: Department of Radiology, University of Michigan Hospital, Ann Arbor 48109-0030, USA.
authors.forename: L K
authors.initials: LK
authors.lastname: Joynt
authors.forename: J F
authors.initials: JF
authors.lastname: Platt
authors.forename: J M
authors.initials: JM
authors.lastname: Rubin
authors.forename: J H
authors.initials: JH
authors.lastname: Ellis
authors.forename: R O
authors.initials: RO
authors.lastname: Bude
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005215:Fasting / Q000502:physiology; D005260:Female; D005502:Food; D006499:Hepatic Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008102:Liver Circulation / Q000502:physiology; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler; D014655:Vascular Resistance / Q000502:physiology