title: [Multiple cavernoma of delayed appearance].
abstract: The authors report on a right fronto-singular cavernous angioma which appeared, in a 46 year-old woman, four years after the excision of a right rolandic localization. Diagnosis suggested on radiological findings was confirmed by histological examination. After a review of the literature the authors discuss possible mechanisms of such delayed appearance of intra-cerebral cavernous angiomas. They suggest the possibility of infraradiologic stage corresponding to a micro-malformation characterized by abnormal capillaries, which has not been yet histologically modified by hemorrhages, thrombosis, fibrosis, gliosis and calcifications.
authors.affiliation: Service de Neurochirurgie, Centre Hospitalier Sainte-Anne, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Gallina
authors.forename: G
authors.initials: G
authors.lastname: Nohra
authors.forename: C
authors.initials: C
authors.lastname: Cioloca
authors.forename: J F
authors.initials: JF
authors.lastname: Meder
authors.forename: F X
authors.initials: FX
authors.lastname: Roux
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006392:Hemangioma, Cavernous / Q000000981:diagnostic imaging / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000503:physiopathology; D011859:Radiography; D013997:Time Factors