title: Calcium channel blocker overdose.
abstract: A case of diltiazem overdose with significant hemodynamic compromise is presented. Multiple therapeutic modalities were attempted with limited results. Control was finally achieved with a combination of norepinephrine, dobutamine, and cardiac pacing. Invasive pulmonary monitoring parameters are reported and were important in the management of this patient. The management of calcium channel blocker overdose and the various available therapeutic modalities are discussed.
authors.affiliation: Department of Emergency Medicine, Brown University School of Medicine, Rhode Island Hospital, Providence 02903, USA.
authors.forename: L
authors.initials: L
authors.lastname: Proano
authors.forename: W K
authors.initials: WK
authors.lastname: Chiang
authors.forename: R Y
authors.initials: RY
authors.lastname: Wang
mesh_terms: D000328:Adult; D002121:Calcium Channel Blockers / Q000493:pharmacokinetics / Q000494:pharmacology / Q000506:poisoning; D002304:Cardiac Pacing, Artificial; D003131:Combined Modality Therapy; D004110:Diltiazem / Q000506:poisoning*; D004280:Dobutamine / Q000008:administration & dosage; D062787:Drug Overdose; D005260:Female; D006801:Humans; D009638:Norepinephrine / Q000008:administration & dosage; D011041:Poisoning / Q000628:therapy; D013406:Suicide, Attempted
chemical_list: D002121:Calcium Channel Blockers; D004280:Dobutamine; D004110:Diltiazem; D009638:Norepinephrine