title: Prenatal diagnosis of retinal nonattachment in the Walker-Warburg syndrome.
abstract: We report on the prenatal ultrasonographic diagnosis of Walker-Warburg syndrome based on cerebral and ocular findings. The ultrasound study done at 37 weeks gestation documented hydrocephalus and retinal nonattachment consistent with this syndrome. The ability to detect retinal nonattachment prenatally may have implications for the prenatal diagnosis of other conditions which have early retinal nonattachment as one of their findings. However, it is uncertain how early in pregnancy this defect can be detected.
authors.affiliation: Prenatal Diagnosis Program, Toronto Hospital-General Division, Ontario, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Chitayat
authors.forename: A
authors.initials: A
authors.lastname: Toi
authors.forename: R
authors.initials: R
authors.lastname: Babul
authors.forename: A
authors.initials: A
authors.lastname: Levin
authors.forename: J
authors.initials: J
authors.lastname: Michaud
authors.forename: A
authors.initials: A
authors.lastname: Summers
authors.forename: J
authors.initials: J
authors.lastname: Rutka
authors.forename: S
authors.initials: S
authors.lastname: Blaser
authors.forename: L E
authors.initials: LE
authors.lastname: Becker
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000196:embryology; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging*; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012163:Retinal Detachment / Q000151:congenital / Q000000981:diagnostic imaging* / Q000196:embryology; D013577:Syndrome; D014463:Ultrasonography