title: Total pelvic exenteration for locally advanced colorectal carcinoma--postoperative complications.
abstract: This study was designed to clarify the postoperative major complications of total pelvic exenteration for locally advanced colorectal cancer. Twenty-six patients (primary disease: 17, recurrent disease: 9) were retrospectively studied. Major complications developed in 30.8% (8 of 26); in 23.5% (4 of 17) for a primary disease and in 44.4% (4 of 9) for a recurrent disease. Only 2 patients (7.7%) died within 30 days after the operation; one patient died of hepatic failure and another of pelvic sepsis. Postoperative ileus developed at a high rate of 11.5% (3 of 26). Ileo-ileal anastomotic leakage developed at a rate of 7.7% (2 of 26) and it commonly occurred following irradiation. The remaining one patient had gastrointestinal bleeding. These 6 patients surviving the operation were successfully managed conservatively. Conclusion was as follows: Total pelvic exenteration should be performed carefully and aggressively regardless of the development of postoperative complications.
authors.affiliation: Department of Surgery, Kurume University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shirouzu
authors.forename: H
authors.initials: H
authors.lastname: Isomoto
authors.forename: T
authors.initials: T
authors.lastname: Morodomi
authors.forename: Y
authors.initials: Y
authors.lastname: Ogata
authors.forename: Y
authors.initials: Y
authors.lastname: Akagi
authors.forename: T
authors.initials: T
authors.lastname: Kakegawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010385:Pelvic Exenteration / Q000009:adverse effects*; D011183:Postoperative Complications