Ulcerative type of colitis associated with the use of high strength pancreatic enzyme supplements in cystic fibrosis.
A 2 1/2-year-old girl with cystic fibrosis, who presented with hematochezia, developed an inflammatory ulcerative type of colitis with mild interstitial fibrosis and colonic narrowing while being treated with high strength pancreatic enzyme supplements. Findings of contrast enema, endoscopy, and colonic biopsy are described. The spectrum of colonic disease associated with the use of high strength pancreatic enzyme supplements in cystic fibrosis patients is discussed.
Ablin
D S
DS
Department of Radiology, University of California Davis Medical Center, Sacramento 95817, USA.
Ziegler
M
M
D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000139:chemically induced* / Q000473:pathology; D003106:Colon / Q000473:pathology; D003251:Constriction, Pathologic / Q000139:chemically induced / Q000473:pathology; D003550:Cystic Fibrosis / Q000188:drug therapy*; D005260:Female; D005355:Fibrosis; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006801:Humans; D010184:Pancreatic Extracts / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use
D010184:Pancreatic Extracts