MR demonstration of Wegener granulomatosis of the infundibulum, a cause of diabetes insipidus.
We report a case of Wegener granulomatosis causing hyperprolactinemia followed by central diabetes insipidus. The initial T1-weighted MR image showed an isointense heterogeneous sellar mass. After the onset of diabetes insipidus, repeat sagittal and postcontrast T1-weighted images showed marked infundibular thickening, enlargement of the sellar mass, and enhancement of both the infundibulum and hypothalamus. Follow-up MR after marked clinical response to corticosteroids showed nearly complete resolution of the aforementioned abnormalities.
Czarnecki
E J
EJ
Department of Diagnostic Radiology, Henry Ford Hospital, Detroit, MI 48202, USA.
Spickler
E M
EM
D000328:Adult; D003919:Diabetes Insipidus / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006966:Hyperprolactinemia / Q000175:diagnosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D010900:Pituitary Diseases / Q000150:complications* / Q000175:diagnosis; D010902:Pituitary Gland / Q000473:pathology