title: [Morphological examination of the lung tissue ablated with Nd;YAG laser in the treatment of bullous pulmonary disease].
abstract: We conducted a morphologic examination of ablated pleurae and bullae to assess the efficacy of Nd;YAG laser irradiation to the lung tissue for the treatment of bullous pulmonary disease. Pleurae and bullae from surgically resected lung tissue to treat pulmonary carcinoma were ablated using a Nd;YAG laser at a power of 10 watts and 1.5 seconds within a 1-centimeter-diameter circle (about 0.2 joule/cm2). Samples were analyzed by light microscopy and scanning electron microscopy. Nd;YAG laser irradiation caused elastic fiber-contraction and gel from collagen both in pleurae irradiated once and in bullae irradiated three times. We conclude that Nd;YAG laser irradiation can be applied to ablate pleurae and bullae into a tight and continuous structure which is important in preventing air leak from the pulmonary parenchyma.
authors.affiliation: Department of Surgery, III, Nara Medical College, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sawabata
authors.forename: K
authors.initials: K
authors.lastname: Nezu
authors.forename: T
authors.initials: T
authors.lastname: Tojo
authors.forename: K
authors.initials: K
authors.lastname: Kawachi
authors.forename: S
authors.initials: S
authors.lastname: Kitamura
mesh_terms: D004646:Emphysema / Q000473:pathology / Q000601:surgery; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects; D008168:Lung / Q000528:radiation effects* / Q000648:ultrastructure*; D008171:Lung Diseases / Q000473:pathology / Q000601:surgery*; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010994:Pleura / Q000528:radiation effects / Q000648:ultrastructure