[Kinetics of hepatic enzymes in anorexia nervosa].
Nervous anorexia in advanced stage causes a generalized deterioration of organs' and apparatuses' functions. In particular, well-known are disorders of both CNS and PNS, changes of the haematic crasis and worsening of the metabolic-endocrine axis. Less well-known, however, is the compromission of function. Analysis of the data obtained in this trial points out a statistically significant correlation between the loss of weight and the variation of level of some liver enzymes (SGPT, SGOT, LDH). These indexes of hepatic necrosis in our opinion, can therefore, be regarded as sound markers not only for a more careful evaluation of the clinical evolution of the anorexic patient, but also for a better monitoring of the effectiveness of diet therapy.
Colombo
L
L
Day Hospital, Area Medica, Ospedale San Paolo, Milano.
Altomare
S
S
Castelli
M
M
Bestetti
A
A
Stanzani
M
M
Colombo
N
N
Picollo
S
S
Pietrasanta
E R
ER
Gnocchi
P
P
Giavardi
L
L
D000328:Adult; D000410:Alanine Transaminase / Q000378:metabolism; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000178:diet therapy / Q000201:enzymology*; D001219:Aspartate Aminotransferases / Q000378:metabolism; D001835:Body Weight; D005260:Female; D006801:Humans; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology* / Q000473:pathology; D009336:Necrosis; D015431:Weight Loss
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase