Interspecific complementation between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation.
Interspecific and intraspecific hybrids were formed between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation and their radiosensitivities were examined. Chinese hamster cell mutants irs1, irs2 and irs3 and mouse mammary carcinoma cell mutants SX9 and SX10 have been found to belong to five different complementation groups. A radiosensitive mouse lymphoma cell line L5178Y-S has been demonstrated to be different from the X-ray sensitive mouse cell mutants M10 and LX830, both of which are derived from L5178Y cells, in their complementation groups. L5178Y-S is also distinct from SX9 and SX10.
Sato
K
K
Division of Radiation Hazards, National Institute of Radiological Sciences, Chiba, Japan.
Chen
D J
DJ
Eguchi-Kasai
K
K
Itsukaichi
H
H
Odaka
T
T
Strniste
G F
GF
D000818:Animals; D002459:Cell Fusion; D002478:Cells, Cultured; D006224:Cricetinae; D003412:Cricetulus; D006822:Hybrid Cells; D051379:Mice; D009154:Mutation; D011830:Radiation Effects; D013045:Species Specificity