title: [Modification of the teratogenic effect of griseofulvin by heat shock in Drosophila melanogaster].
abstract: Modification of the teratogenic effect of griseofulvin by hyperthermia was demonstrated in line Canton-S of Drosophila melanogaster. Heat shock (37 degrees C for 45 min) during II instar larvae significantly decreased the frequency of chemomorphoses that phenocopy ey mutation (eyeless, 4:2.0).
authors.forename: O A
authors.initials: OA
authors.lastname: Isaenko
authors.forename: P Ia
authors.initials: PIa
authors.lastname: Shvartsman
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000235:genetics; D005260:Female; D006118:Griseofulvin / Q000633:toxicity*; D006358:Hot Temperature; D007814:Larva / Q000187:drug effects / Q000235:genetics; D008297:Male; D009154:Mutation; D012769:Shock / Q000235:genetics*; D013723:Teratogens / Q000633:toxicity*
chemical_list: D013723:Teratogens; D006118:Griseofulvin