The effect of Chelidonium majus herb extract on choleresis in the isolated perfused rat liver.
The total ethanolic extract, the phenolic and the alkaloidal fraction of the herb of Chelidonium majus L. (Papaveraceae) were tested for their choleretic activity using the isolated perfused rat liver. The total extract significantly caused chloresis by increasing the bile acid independent flow (BAIF); the observed weak activity of both fractions, tested each and as combination, however, was not significant.
Vahlensieck
U
U
Hahn
R
R
Winterhoff
H
H
Gumbinger
H G
HG
Nahrstedt
A
A
Kemper
F H
FH
D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000502:physiology*; D019684:Magnoliopsida; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D001647:Bile Acids and Salts; D010936:Plant Extracts