title: The role of tranexamic acid in the treatment of giant hemangiomas in newborns.
abstract: Giant hemangiomas occurring in the neonatal period often present a therapeutic challenge, especially when confounded by consumptive coagulopathy (Kasabach-Merritt syndrome). We treated three infants with tranexamic acid after therapy with corticosteroids was ineffective. One patient had a partial response. The remaining two developed progressive disease.
authors.affiliation: Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
authors.forename: A B
authors.initials: AB
authors.lastname: Morad
authors.forename: K L
authors.initials: KL
authors.lastname: McClain
authors.forename: A K
authors.initials: AK
authors.lastname: Ogden
mesh_terms: D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006392:Hemangioma, Cavernous / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014148:Tranexamic Acid / Q000627:therapeutic use*
chemical_list: D014148:Tranexamic Acid; D011241:Prednisone