title: [Hypokalemic rhabdomyolysis and thiazide diuretics. 3 clinical cases].
abstract: Rhabdomyolysis is an acute skeletal muscle disorder characterized by altered integrity of the cell membranes of muscle fiber cells and can be caused by a variety of factors whose nature is not necessarily traumatic. Hypokalemia is one of the most common metabolic causes, accounting for about 14-28% of rhabdomyolytic syndromes. We report and discuss three cases of hypokalemia caused by diuretic treatment with hydrochlorothiazide: the main clinical features were muscle symptoms following massive rhabdomyolysis.
authors.affiliation: Istituto di Terapia Medica, Università degli Studi, IRCCS Policlinico San Matteo di Pavia.
authors.forename: S S
authors.initials: SS
authors.lastname: Girola
authors.forename: A
authors.initials: A
authors.lastname: Mazzone
authors.forename: M
authors.initials: M
authors.lastname: Moroni
authors.forename: C
authors.initials: C
authors.lastname: Porta
authors.forename: G
authors.initials: G
authors.lastname: Nastasi
authors.forename: A
authors.initials: A
authors.lastname: Notario
mesh_terms: D000328:Adult; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000009:adverse effects*; D007008:Hypokalemia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000175:diagnosis; D013997:Time Factors
chemical_list: D006852:Hydrochlorothiazide; D003402:Creatine Kinase