[A mutable X(Z)-chromosome isolated from a natural population of Drosophila melanogaster].
In 1986, a mutable XZ-chromosome, in which mutation at genes yellow, white, and singed were recorded, was isolated from a natural population of Drosophila melanogaster from Zaporozh'e. Visible mutations in the region garnet-forked were also detected. Mutations appeared at a rate of about 10(-4) and were probably postmeiotic. Cytological analysis showed that two types of inversions occurred independently in XZ-chromosome. Specific features of this chromosome are hypermutability of the white locus (the mutation rate was approximately 10(-3) and a hot spot for chromosomal rearrangements in the terminal segment of the X-chromosome.
Iurchenko
N N
NN
Zakharov
I K
IK
D000483:Alleles; D000818:Animals; D007446:Chromosome Inversion; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D006579:Heterozygote; D009154:Mutation; D012016:Reference Values; D012729:Sex Chromosome Aberrations; D014960:X Chromosome