Carcinoma of the colon in a child.
A 13-year-old boy presented with carcinoma of the ascending colon. He had had intermittent abdominal pain for about one year, with body weight loss, prior to admission. Physical examination showed diffuse abdominal tenderness, but no palpable mass. Lower GI barium study and colonofibroscopic examination showed a protruding mass over the proximal ascending colon. At operation, right hemicolectomy with ileotransversecolostomy was performed, the pathologic finding was adenocarcinoma, signet-ring cell type. Although chemotherapy with 5-fluorouracil, mitomycin, and levamisole were given subsequently, the patient expired one year after surgery because of multiple metastasis. Carcinoma of the colon is extremely rare in the young. Mucin-producing adenocarcinoma is the most predominant type of colon cancer, and most are of signet-ring cell carcinoma. While prognosis is relatively bright in adult, the prognosis is quite unfavorable in children because of the preponderance of the poor histological characteristics and the difficulty of diagnosis.
Ko
Y S
YS
Department of Pediatrics, Cathay General Hospital, Taipei, Taiwan, R.O.C.
Lin
L H
LH
Chen
D F
DF
D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D000293:Adolescent; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D011379:Prognosis