title: A new extremely large allele at the D1S80 (MCT118) locus.
abstract: A new extremely large allele at locus D1S80, segregating in a three-generation family is described. The length of PCR-generated allele is approximately 1000 bp. Restriction analysis indicates that this increase is due to an increased number of basic core sequence. The assessed number of tandem repeats is in range 52-55, corresponding to 979-1027 bp exact length of the PCR-generated fragment.
authors.affiliation: Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava.
authors.forename: L
authors.initials: L
authors.lastname: Kádasi
authors.forename: T
authors.initials: T
authors.lastname: Bohusovà
mesh_terms: D000483:Alleles; D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011296:Prenatal Diagnosis; D012091:Repetitive Sequences, Nucleic Acid; D044465:White People / Q000235:genetics
chemical_list: D004247:DNA