title: Angiosarcoma of the eyelid.
abstract: BACKGROUND
  Angiosarcomas are uncommon malignant tumours of vascular endothelium. They frequently affect the face and scalp, but to our knowledge there are only three reports of eyelid involvement.
  
  
  RESULTS
  We report a case of angiosarcoma arising from the eyelid skin in a 79-year-old woman. Treatment was surgical with wide excision and staged reconstruction of the defect. Systemic oncological work-up for metastatic disease was negative. Adjuvant systemic chemotherapy and radiotherapy were considered but were not felt to be of proven benefit and were not used. The patient died seven months after presentation from a myocardial infarct.
  
  
  CONCLUSIONS
  Angiosarcoma should be considered in the differential diagnosis of unusual or atypical eyelid lesions. Management is wide surgical excision, although adjuvant systemic therapy should be considered in selected cases in consultation with an oncologist.
authors.affiliation: Department of Surgery, Royal Brisbane Hospital, Herston, Queensland, Australia.
authors.forename: L C
authors.initials: LC
authors.lastname: Bray
authors.forename: T J
authors.initials: TJ
authors.lastname: Sullivan
authors.forename: K
authors.initials: K
authors.lastname: Whitehead
mesh_terms: D000368:Aged; D005142:Eyelid Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006394:Hemangiosarcoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013601:T-Lymphocytes / Q000473:pathology
chemical_list: D005169:Factor VIII