title: Primary malignant melanoma of the esophagus.
abstract: Primary malignant melanoma of the esophagus is a rare disease. A case is reported and the newer diagnostic techniques of immunohistologic identification of the tumor by positive reaction to the HMB-45 antigen, as well as immunoscintigraphy with Technetium-99m-labeled melanoma monoclonal antigen for the demonstration of distant metastasis, is presented. A current review of the literature on this uncommon tumor is presented, and treatment options are discussed. A total esophagectomy remains the treatment of choice. Four long-term (> 5 years) survivors after adequate surgical removal have been recorded in the literature.
authors.affiliation: Department of Surgery, Northwestern University Medical School, Chicago, IL 60611, USA.
authors.forename: A W
authors.initials: AW
authors.lastname: Joob
authors.forename: G K
authors.initials: GK
authors.lastname: Haines
authors.forename: M S
authors.initials: MS
authors.lastname: Kies
authors.forename: T W
authors.initials: TW
authors.lastname: Shields
mesh_terms: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins