title: [Repair of large cranial defect using allogeneic cranial bone and bone morphogenetic protein].
abstract: We have successfully treated 4 patients with large cranial defects using a composite of allogeneic cranial bone, BMP (bone morphogenetic protein), pedicled periosteum and skin flap. The size of the cranial defects ranged from 9 cm x 7 cm to 13 cm x 11.5 cm. One to two years' follow-up showed that the wounds in all patients healed primarily with good appearance. The allogeneic bone graft was absorbed and substituted by new bone formation.
authors.affiliation: Beijing Jishuitan Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: G
authors.initials: G
authors.lastname: Ma
authors.forename: D
authors.initials: D
authors.lastname: Li
mesh_terms: D000328:Adult; D019485:Bone Morphogenetic Proteins; D016025:Bone Transplantation / Q000379:methods; D002058:Burns, Electric / Q000601:surgery; D006133:Growth Substances / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011506:Proteins / Q000627:therapeutic use*; D012886:Skull / Q000293:injuries* / Q000601:surgery*; D013524:Surgical Flaps
chemical_list: D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D011506:Proteins