Treatment of experimental rabbit infective endocarditis due to a multidrug-resistant Pseudomonas aeruginosa with high-dose ceftazidime alone and combined with amikacin or sulbactam or both.
Xiong
Y Q
YQ
Laboratorie d'Antibiologie Clinique et Expérimentale, Faculté de Médecine, C.H.U., Nantes, France.
Caillon
J
J
Zhou
X Y
XY
Potel
G
G
Bugnon
D
D
Le Conte
P
P
Le Gallou
F
F
Le Floch
R
R
Baron
D
D
Drugeon
H
H
D000583:Amikacin / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D000818:Animals; D001021:Aortic Valve; D002442:Ceftazidime / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology; D004334:Drug Administration Schedule; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D004359:Drug Therapy, Combination; D004696:Endocarditis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006349:Heart Valve Diseases / Q000188:drug therapy; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011817:Rabbits; D013407:Sulbactam / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D001618:beta-Lactamases / Q000096:biosynthesis
D000583:Amikacin; D002442:Ceftazidime; D001618:beta-Lactamases; D013407:Sulbactam