title: The natural history of periodontal disease. The correlation of selected microbiological parameters with disease severity in Sri Lankan tea workers.
abstract: The purpose of this study was to assess the prevalence of A. actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia, and their association with periodontal disease states in a population sample from Sri Lanka. Based on clinical parameters, a total of 536 sites in 268 male Sri Lankan tea workers were categorized as healthy, or showing gingivitis only, moderate or advanced periodontitis. Bacterial samples were obtained from all sites and the three target bacteria identified by indirect immunofluorescence. P. intermedia, P. gingivalis and A. actinomycetemcomitans were found in 76%, 40% and 15% of the subjects, respectively. Of the 536 periodontal sites, 10.5% were categorized with "no disease", 14% "gingivitis only": 59% with moderate and 16% with advanced periodontitis. The prevalence of P. gingivalis and P. intermedia was significantly higher in sites with moderate and advanced periodontitis than in sites with no disease or gingivitis only. A. actinomycetemcomitans was not found in healthy sites, but occurred with equal frequency in sites with gingivitis, moderate and advanced periodontitis. The association between these three bacteria and periodontal diseases in Sri Lankan tea laborers was similar to that described for other non-industrialized and industrialized countries.
authors.affiliation: Department of Periodontology, Dental Faculty, University of Oslo, Norway.
authors.forename: H R
authors.initials: HR
authors.lastname: Preus
authors.forename: A
authors.initials: A
authors.lastname: Anerud
authors.forename: H
authors.initials: H
authors.lastname: Boysen
authors.forename: R G
authors.initials: RG
authors.lastname: Dunford
authors.forename: J J
authors.initials: JJ
authors.lastname: Zambon
authors.forename: H
authors.initials: H
authors.lastname: Löe
mesh_terms: D000293:Adolescent; D000328:Adult; D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification*; D015331:Cohort Studies; D015169:Colony Count, Microbial; D019084:Fluorescent Antibody Technique, Indirect; D005889:Gingival Recession / Q000382:microbiology / Q000503:physiopathology; D005891:Gingivitis / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D016272:Occupational Health; D017622:Periodontal Attachment Loss / Q000382:microbiology / Q000503:physiopathology; D010510:Periodontal Diseases / Q000382:microbiology* / Q000503:physiopathology*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000382:microbiology / Q000503:physiopathology; D010518:Periodontitis / Q000382:microbiology / Q000503:physiopathology; D010519:Periodontium / Q000382:microbiology / Q000502:physiology; D016966:Porphyromonas gingivalis / Q000302:isolation & purification*; D015995:Prevalence; D018713:Prevotella intermedia / Q000302:isolation & purification*; D013188:Sri Lanka; D013662:Tea
chemical_list: D013662:Tea