title: [Evaluation of nasal mucociliary clearance with a modified saccharin test].
abstract: To measure the complex nasal clearance we propose to perform our variation of the Andersen saccharin method as a saccharin liquid test (SLT). The application of 3 molar aqueous sodium saccharin solutions with a Wiretrol capillary on the concha nasalis inferior or media allows simple handling, exact dosage, minimal nasal irritation and an increase in reproducibility. Application of 1 microlitre is sufficient to carry out the test. In the present study 48 healthy volunteers without any nose disease or history of sinusitis showed a saccharin transport rate of 10.4 (SD 4.2) minutes.
authors.affiliation: Universitäts-Hals-Nasen-Ohrenklinik Otto Körner Rostock.
authors.forename: E G
authors.initials: EG
authors.lastname: Kleinschmidt
authors.forename: G
authors.initials: G
authors.lastname: Witt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002925:Ciliary Motility Disorders / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology; D009297:Nasal Mucosa / Q000503:physiopathology*; D012016:Reference Values; D015203:Reproducibility of Results; D012439:Saccharin; D012907:Smoking / Q000009:adverse effects / Q000503:physiopathology
chemical_list: D012439:Saccharin