title: On the association between adult blood pressure and dermatoglyphics as prenatal markers of development.
abstract: OBJECTIVE
  To examine the relationships between finger and palm print (dermatoglyphic) features and, first, the presence or absence of hypertension, and, secondly, blood pressure levels in non-hypertensive subjects.
  
  
  METHODS
  Prints were available from 841 male World War II veteran twins (393 pairs, 55 individual cotwins), who were born in the USA between 1917 and 1927 and examined three different times between 1969 and 1987. At each examination the hypertensive status was assessed by blood pressure measurement, use of antihypertensive medications and two physicians' diagnostic impressions.
  
  
  RESULTS
  Subjects defined as hypertensive did not differ in dermatoglyphics from non-hypertensives for any trait examined. There were 60 twin-pairs discordant for hypertension; hypertensive cotwins showed lower ridge counts on the left hand, and this relationship was the opposite of what has previously been reported. Using only normotensive subjects at all three examinations, there was little consistent relationship between blood pressures (adjusted for age, body mass and alcohol consumption) and various dermatoglyphic features, except for lower palmar a-b ridge count in those with higher systolic blood pressure.
  
  
  CONCLUSIONS
  Unless the in utero development of dermatoglyphics in relation to blood pressure is substantially different between singleton and twin pregnancies, there are no useful relationships between dermatoglyphics and hypertension or strong relationships between the presence of certain 'dermatoglyphic markers of impaired fetal development' and blood pressure in subjects who remain normotensive until early in their seventh decade.
authors.affiliation: Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202-5251, USA.
authors.forename: T
authors.initials: T
authors.lastname: Reed
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers; D001794:Blood Pressure; D003878:Dermatoglyphics; D005314:Embryonic and Fetal Development; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged
chemical_list: D015415:Biomarkers