Visually guided eye movements in patients with Wallenberg's syndrome.
To determine the lesions and the lateralization in patients with Wallenberg's syndrome, visually-guided eye movements were quantitatively analysed and these findings were compared with a lesioned site as revealed by magnetic resonance imaging (MRI). The 8 patients could be clearly classified into two subgroups based on the functional test of eye movements. In 4 patients, optokinetic nystagmus (OKN), pursuit eye movements and fixation-suppression of caloric nystagmus (FS), utilizing the slow phase velocity as a parameter, were impaired toward the lesioned side in the medulla. In the remaining 4 patients, OKN and pursuit eye movements were impaired toward the side contralateral to the lesion, whereas FS toward the lesioned side, indicating a lesion affecting not only the medulla but also the inferior peduncle and/or the cerebellum. Therefore, the functional visually-guided eye movements can provide a useful test battery with which to detect the lesion site in Wallenberg's syndrome.
Ogino
S
S
Department of Otolaryngology, St. Marianna University School of Medicine, Kanagawa, Japan.
Kato
I
I
Sakuma
A
A
Takahashi
K
K
Takeyama
I
I
Nakamura
T
T
Kanayama
R
R
D000792:Angiography; D002531:Cerebellum / Q000503:physiopathology; D004585:Electrooculography; D005133:Eye Movements; D005260:Female; D006801:Humans; D014854:Lateral Medullary Syndrome / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008526:Medulla Oblongata / Q000503:physiopathology; D008875:Middle Aged; D017120:Nystagmus, Optokinetic; D011698:Pursuit, Smooth; D014711:Vertebral Artery / Q000000981:diagnostic imaging