title: Chromatographic, immunochemical and electrophoretic studies of human uterotrophic placental factor (hUTPF).
abstract: The human uterotrophic placental factor (hUTPF) is a protein obtained from human term placentae and acts on uterine growth, mammary gland, and blastocyst development and implantation. In the present work, we further define some molecular characteristics of hUTPF using chromatographic, electrophoretic and immunochemical methods. It is concluded that in human term placenta a high molecular weight hUTPF is present, bound to albumin and immunoglobulins, which could represent a storage or transport form of this factor. hUTPF presents several molecular forms, one of them of 270 kDa and others of approximately 90 kDa and 27 kDa.
authors.affiliation: Instituto de Investigaciones Materno Infantil (IDIMI), Facultad de Medicina, Universidad de Chile, Santiago.
authors.forename: M P
authors.initials: MP
authors.lastname: Boric
authors.forename: G
authors.initials: G
authors.lastname: Iñiguez
authors.forename: I
authors.initials: I
authors.lastname: Rojas
authors.forename: A
authors.initials: A
authors.lastname: Salinas
authors.forename: E
authors.initials: E
authors.lastname: Perez
authors.forename: F
authors.initials: F
authors.lastname: Beas
mesh_terms: D000818:Animals; D015153:Blotting, Western / Q000379:methods; D002852:Chromatography, Ion Exchange / Q000379:methods; D003208:Concanavalin A; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D005260:Female; D006801:Humans; D007120:Immunochemistry / Q000379:methods; D051379:Mice; D008807:Mice, Inbred BALB C; D008970:Molecular Weight; D009929:Organ Size / Q000187:drug effects; D010924:Placental Extracts / Q000008:administration & dosage / Q000494:pharmacology; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000737:chemistry*; D014599:Uterus / Q000737:chemistry* / Q000187:drug effects / Q000254:growth & development
chemical_list: D010924:Placental Extracts; D011257:Pregnancy Proteins; D003208:Concanavalin A