title: Hepatobiliary pruritus: what are effective treatments?
abstract: Pruritus is a common symptom in patients with hepatobiliary disease. Numerous treatments have been attempted. We review published therapeutic trials for hepatobiliary pruritus and utilize statistical analysis to evaluate treatment results. Randomized placebo-controlled studies show cholestyramine, rifampin, naloxone, S-adenosylmethionine, prednisolone, and propofol to be effective. Suggestions for future studies of the treatment of hepatobiliary puruitus are proposed.
authors.affiliation: Division of Dermatology, Philadelphia College of Osteopathic Medicine, PA, USA.
authors.forename: C S
authors.initials: CS
authors.lastname: Connolly
authors.forename: G R
authors.initials: GR
authors.lastname: Kantor
authors.forename: H
authors.initials: H
authors.lastname: Menduke
mesh_terms: D001660:Biliary Tract Diseases / Q000150:complications*; D002986:Clinical Trials as Topic; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology*