Restriction endonucleases functionally interacting with two DNA sites.
Simultaneous interaction with two recognition sites was found to be a precondition for DNA cleavage by certain type-II and type-III restriction endonucleases. Nevertheless, the molecular mechanisms of the protein-DNA interaction are different between members of both classes of enzymes.
Krüger
D H
DH
Institute of Medical Virology, Humboldt University School of Medicine (Charité), Berlin, Germany.
Kupper
D
D
Meisel
A
A
Tierlich
M
M
Reuter
M
M
Schroeder
C
C
D001665:Binding Sites; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism*; D015263:Deoxyribonucleases, Type III Site-Specific / Q000378:metabolism*
D004247:DNA; D015252:Deoxyribonucleases, Type II Site-Specific; D015263:Deoxyribonucleases, Type III Site-Specific