Pharmacologic considerations in the management of temporomandibular disorders.
The management of patients with temporomandibular disorders may involve the use of a number of modalities, including pharmacotherapy. This manuscript provides an overview of the pharmacology of agents currently employed for this purpose, with an emphasis on the major drug group used, the non-steroidal anti-inflammatory drugs (NSAIDs). A brief discussion of opioid analgesics, tricyclic antidepressants, muscle relaxants, benzodiazepines, steroids, and local anaesthetics is also included, and guidelines for their use are suggested.
Haas
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Department of Anesthesia, Faculty of Dentistry, University of Toronto.
D000701:Analgesics, Opioid / Q000009:adverse effects / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000627:therapeutic use; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D001569:Benzodiazepines; D000075202:Contraindications; D006801:Humans; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D015990:Placebo Effect; D013256:Steroids; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy*
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000929:Antidepressive Agents, Tricyclic; D009125:Muscle Relaxants, Central; D013256:Steroids; D001569:Benzodiazepines