Absorbable polydioxanone suture and results in total anomalous pulmonary venous connection.
BACKGROUND
Despite theoretical advantages of absorbable suture in the growing vascular anastomosis, there has not been a documented advantage over nonabsorbable suture in preventing late anastomotic stenosis in total anomalous pulmonary venous connection (TAPVC).


METHODS
We reviewed our experience from 1982 to 1994 with 65 hospital survivors of total TAPVC repair to examine the influence of suture type on survival and incidence of late pulmonary venous obstruction. From 1982 until 1988, we used continuous nonabsorbable polypropylene suture for the pulmonary venous-left atrial anastomosis in supracardiac, infracardiac, and mixed types of TAPVC: In 1989, we adopted a running absorbable polydioxanone suture technique. Cardiac catheterization and echocardiography were used to evaluate late pulmonary venous obstruction.


RESULTS
Late pulmonary venous obstruction occurred in 17% (4/23) of survivors after repair with polypropylene suture compared with 3.2% (1/32) after repair with polydioxanone suture (p < 0.05). There were no instances of late pulmonary venous obstruction in the intracardiac TAPVC group (0/10). All late pulmonary venous obstructions occurred within 16 months after operation. The actuarial 3-year and 5-year freedom from late pulmonary venous obstruction was 100% for intracardiac TAPVC, 96% for the polydioxanone group, and 81% for the polypropylene group. Five patients died late (5/65, 7.7%), 3 in the polypropylene suture group (3/23, 13%) and 2 in the polydioxanone group (2/32, 6%).


CONCLUSIONS
Continuous absorbable polydioxanone suture for the repair of TAPVC results in a low incidence of late pulmonary venous obstruction and death and appears to offer advantages over a continuous nonabsorbable suture. A continuous nonabsorbable suture may limit growth of a vascular anastomosis, particularly one involving a "low-pressure" anastomosis such as in the repair of TAPVC:
Hawkins
J A
JA
Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, USA.
Minich
L L
LL
Tani
L Y
LY
Ruttenberg
H D
HD
Sturtevant
J E
JE
McGough
E C
EC
D000042:Absorption; D000714:Anastomosis, Surgical; D002675:Child, Preschool; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016687:Polydioxanone; D011183:Postoperative Complications; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000601:surgery*; D011668:Pulmonary Veno-Occlusive Disease / Q000517:prevention & control; D013536:Suture Techniques; D013537:Sutures; D016896:Treatment Outcome
D016687:Polydioxanone