[Casual influence of the stimulation of macrophage production by proteose-peptone, in the experimental infection of mice by Plasmodium berghei].
Proteose-peptone is a known powerful stimulator of macrophages. This stimulation was studied in an experimental malaria infection model, using Plasmodium berghei in mice. Parasitemia and mortality did not change in stimulated animals, and macrophage mobilization, contrary to other published papers, was not effective to increase either parasite levels in the blood or mortality.
Arantes
S C
SC
Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
Braz
L M
LM
Amato Neto
V
V
D000818:Animals; D002364:Caseins / Q000276:immunology*; D007111:Immunity, Cellular; D008264:Macrophages / Q000276:immunology* / Q000502:physiology; D008288:Malaria / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010446:Peptide Fragments / Q000276:immunology*; D010461:Peptones / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology; D010587:Phagocytosis; D010962:Plasmodium berghei / Q000276:immunology*
D002364:Caseins; D010446:Peptide Fragments; D010461:Peptones; C018135:proteose-peptone