title: Clinical characteristics of primary mitral valve prolapse syndrome in children.
abstract: Sixty-seven children (40 girls and 27 boys) suffering from primary mitral valve prolapse (MVP) were studied. The age of these subjects was 5 to 18 years with the mean 12.8 +/- 3.3 years. MVP was diagnosed on the basis of physical and echocardiographic examination. In every case following studies were performed: routine and 24-hours ECG (according to Holter method), echocardiography, and physical performance test (according to Bruce protocol). The cause of referring the child to cardiologist were: cardiac murmur with/or midsystolic click in 85%, chest pain in 31%, feeling of cardiac palpitations in 40%, loss of consciousness in 40%, increased fatigability in 22%, feeling of dyspnoea in 10.5% (there were often more than one symptom in the same subject). Familial inheritance of MVP was suggested in over 20% of our patients. Asthenic constitution with orthopedic disorders (e.g. important scoliosis, pectus excavatum etc.) was found in about 20% of studied children. In 15% so called silent MVP was recognized. In 19% of subjects mitral valve leaflets inspection indicated their thickening and redundancy. In 67% routine ECG showed abnormalities of cardiac rhythm, conduction or repolarization. During Holter monitoring rhythm disturbances were detected in 22% of patients. Physical performance test results were normal in every case.
authors.affiliation: Department of Paediatric Cardiology, Silesian Medical School, Katowice, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Rokicki
authors.forename: J
authors.initials: J
authors.lastname: Krzystolik-Ladzińska
authors.forename: B
authors.initials: B
authors.lastname: Goc
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008945:Mitral Valve Prolapse / Q000175:diagnosis* / Q000235:genetics