Acute limb ischemia due to malignant arterial embolism from a metastatic germ cell tumor.
Arterial tumor embolization is a rare but serious complication of neoplastic disease. The majority of these tumors are associated with primary or secondary lung malignancies, originating from pulmonary vein metastasis or from an atrial mass. Malignant germ cell tumors primarily disseminate to the retroperitoneal lymph nodes and lung, and to the brain and liver later in the course of the disease. A germ cell tumor metastasis embolizing to the iliac-femoral arterial system has not yet been reported. We report a metastatic  embolism in a patient with disseminated embryonal cell carcinoma causing acute limb ischemia, managed by surgical embolectomy. The sudden development of limb ischemia in a patient with a germ cell tumor should alert the physician to the possibility of tumor embolism.
Stein
M E
ME
Chemotherapy Unit, Northern Israel Oncology Center, Haifa.
Drumea
K
K
Ben-Itshak
O
O
Hoffman
A
A
Eyal
A
A
Moshkovitz
B
B
Haim
N
N
D004452:Echocardiography; D017128:Embolectomy; D018237:Germinoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology*; D007866:Leg / Q000098:blood supply*; D008297:Male; D009360:Neoplastic Cells, Circulating; D011859:Radiography; D013736:Testicular Neoplasms / Q000150:complications / Q000473:pathology*; D013923:Thromboembolism / Q000150:complications* / Q000601:surgery