Ketorolac tromethamine for postoperative analgesia in oral surgery.
Sixty patients were randomly allocated to receive placebo or i.v. ketorolac tromethamine 30 mg during the induction of anaesthesia for dental removal. Pain score (VAS), mouth opening and oedema were evaluated. Pain intensity was assessed by the patient using a visual analog scale 1, 2, 6 and 24 hrs after surgery. Mouth opening and oedema were evaluated at the same times by an observer not implicated in the study. In ketorolac group, pain relief was better at each considered time (VAS: p < 0.001). Oedema was also significantly lesser. There was no difference in mouth opening. No side effect was observed. These data suggest that ketorolac reduces post-oral surgery pain and oedema.
Pendeville
P E
PE
Department of Anaesthesiology, UCL Medical School, Saint-Luc Hospital, Brussels, Belgium.
Van Boven
M J
MJ
Contreras
V
V
Scholtes
J L
JL
Fosseur
G
G
Lechien
P
P
Reychler
H
H
D000293:Adolescent; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D004311:Double-Blind Method; D004338:Drug Combinations; D004487:Edema / Q000188:drug therapy; D005260:Female; D006801:Humans; D020911:Ketorolac Tromethamine; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy*; D014046:Tolmetin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014081:Tooth Extraction; D014325:Tromethamine / Q000008:administration & dosage*
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D014325:Tromethamine; D020911:Ketorolac Tromethamine; D014046:Tolmetin