title: Serum 25-hydroxycholecalciferol concentration in newly detected hypertension.
abstract: Although blood concentrations of the active metabolite 1,25-dihydroxyvitamin D are raised in hypertension, concentrations of 25-hydroxyvitamin D, the main vitamin D metabolite, do not appear to have been reported in newly detected hypertension. Serum levels of 25-hydroxycholecalciferol were measured in 186 newly detected hypertensive patients (blood pressure > 160/95 mm Hg and never on antihypertensive medication) and normotensive controls individually matched by sex, age (+/- 2 years), ethnicity, and date of interview. Serum 25-hydroxycholecalciferol levels were similar in cases (mean (SD) = 64 (21) nmol/L) and controls (67 (28) nmol/L, P = .20). We conclude that serum 25-hydroxycholecalciferol, a marker of body vitamin D, is normal in hypertension.
authors.affiliation: Department of Community Health, University of Auckland, New Zealand.
authors.forename: R
authors.initials: R
authors.lastname: Scragg
authors.forename: I
authors.initials: I
authors.lastname: Holdaway
authors.forename: V
authors.initials: V
authors.lastname: Singh
authors.forename: P
authors.initials: P
authors.lastname: Metcalf
authors.forename: J
authors.initials: J
authors.lastname: Baker
authors.forename: E
authors.initials: E
authors.lastname: Dryson
mesh_terms: D000367:Age Factors; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002112:Calcifediol / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D044469:Racial Groups; D012737:Sex Factors
chemical_list: D002112:Calcifediol