Vasopressin in the brain of a desert hibernator, the jerboa (Jaculus orientalis): presence of sexual dimorphism and seasonal variation.
The distribution of vasopressin innervation in the brain of the jerboa (Jaculus orientalis) was investigated, with special attention to sex differences and seasonal variations. Vasopressin perikarya were observed in the paraventricular and supraoptic nuclei, the suprachiasmatic nucleus, the periventricular nucleus, the medial preoptic area, the bed nucleus of the stria terminalis, and the medial amygdaloid nucleus. In addition, vasopressin cell bodies were observed in the ventral retrochiasmatic area. After treatment with colchicine, vasopressin perikarya were also observed around the organum vasculosum laminae terminalis, in the medial diagonal band of Broca, and in the dorsal medial preoptic nucleus. Vasopressin fibers were also found to be more widespread in the jerboa brain than in other rodents. Fibers were observed in the medial diagonal band of Broca, the stria medullaris, the tuber cinerum, the area postrema, the medial vestibular nucleus, and the dorsal motor nucleus of the vagus. Sexual dimorphism and seasonal variation in vasopressin immunoreactivity were observed in areas that not only showed a testosterone-dependent vasopressin innervation in other rodents but also in the paratenial and mediodorsal thalamic nuclei, the tuber cinerum, the supramammillary complex, the zona incerta, the interpeduncular complex, and the dorsal and medial raphe nuclei. A denser vasopressin innervation was observed in spring/summer (sexual active period) than in autumn. Numerous brain structures contained vasopressin receptors (cerebral cortex, hypothalamus, substantia nigra, dentate gyrus, thalamic nuclei, superior colliculus, dorsal cochlear nucleus, and cerebellum); no sex- or season-related differences were observed. These data indicate a high level of vasopressin in the jerboa brain, which may reflect an adaptation to its harsh bioclimatic environment.
Lakhdar-Ghazal
N
N
Département de Biologie, Faculté des Sciences, Université Mohamed V, Rabat, Morocco.
Dubois-Dauphin
M
M
Hermes
M L
ML
Buijs
R M
RM
Bengelloun
W A
WA
Pévet
P
P
D000222:Adaptation, Physiological; D000818:Animals; D001833:Body Temperature Regulation / Q000502:physiology; D001923:Brain Chemistry / Q000502:physiology*; D005260:Female; D006605:Hibernation / Q000502:physiology*; D008297:Male; D009411:Nerve Endings / Q000502:physiology; D009412:Nerve Fibers / Q000502:physiology; D009490:Neurosecretory Systems / Q000502:physiology; D017483:Receptors, Vasopressin / Q000032:analysis; D012377:Rodentia / Q000378:metabolism*; D012621:Seasons; D012727:Sex Characteristics; D014667:Vasopressins / Q000032:analysis*; D014882:Water-Electrolyte Balance / Q000502:physiology
D017483:Receptors, Vasopressin; D014667:Vasopressins