title: Langerhans cell histiocytosis involving the sphenoid sinus and superior orbital fissure.
abstract: We report Langerhans cell histiocytosis involving the sphenoid sinus and extending to the orbital apex. MR and CT imaging, particularly with contrast, both were helpful in defining the extent of the lesion before treatment. MR was a useful examination for follow-up after treatment. Langerhans cell histiocytosis should be considered in the differential diagnosis of lesions of this region in the pediatric age group.
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Stromberg
authors.forename: A M
authors.initials: AM
authors.lastname: Wang
authors.forename: T E
authors.initials: TE
authors.lastname: Huang
authors.forename: F A
authors.initials: FA
authors.lastname: Vicini
authors.forename: P A
authors.initials: PA
authors.lastname: Nowak
mesh_terms: D000293:Adolescent; D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009915:Orbit / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis* / Q000473:pathology; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000473:pathology; D013101:Sphenoid Sinus / Q000473:pathology*; D014057:Tomography, X-Ray Computed