title: Acute myocardial infarction during coronary angioplasty associated with heparin-induced thrombocytopenia.
abstract: Heparin-induced thrombocytopenia is a well-recognized complication after cardiac or vascular surgery, but it has not been previously reported during percutaneous coronary interventions. This case study describes a patient who developed an acute myocardial infarction during coronary angioplasty in association with the abrupt onset of heparin-induced thrombocytopenia. Since balloon angioplasty achieved a satisfactory angiographic result with a widely patent epicardial vessel, it is postulated that acute myocardial infarction in this patient may have been caused by platelet aggregation and activation resulting in distal small vessel thrombosis and spasm.
authors.affiliation: Division of Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.
authors.forename: B K
authors.initials: BK
authors.lastname: Gupta
authors.forename: M P
authors.initials: MP
authors.lastname: Savage
authors.forename: A N
authors.initials: AN
authors.lastname: Brest
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D009203:Myocardial Infarction / Q000209:etiology*; D013921:Thrombocytopenia / Q000139:chemically induced*
chemical_list: D006493:Heparin