Radon exposure and cancers other than lung cancer in Swedish iron miners.
Data are presented on the risks of cancers other than lung cancer in a cohort of iron miners from northern Sweden occupationally exposed to elevated levels of the radioactive gas radon. Compared with rates for the four northernmost counties of Sweden, mortality was increased for all cancers other than lung cancer (ratio of observed to expected deaths 1.21, 95% confidence interval 1.03-1.41), stomach cancer (ratio of observed to expected deaths 1.45, 95% confidence interval 1.04-1.98), and rectal cancer (ratio of observed to expected deaths 1.94, 95% confidence interval 1.03-3.31). Despite these overall increases, mortality was not significantly associated with cumulative exposure to radon, either for all cancers other than lung cancer or for any site of cancer other than lung cancer individually. However, the data from this cohort on its own have limited power; and for several sites of cancer the data in this study would be consistent with a radon-related increase. Further study of cancers other than lung cancer in populations exposed to radon is required.
Darby
S C
SC
Imperial Cancer Research Fund, University of Oxford, United Kingdom.
Radford
E P
EP
Whitley
E
E
D006801:Humans; D007501:Iron; D008297:Male; D008906:Mining; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011886:Radon / Q000009:adverse effects*; D013548:Sweden
D007501:Iron; D011886:Radon