Neonatal lupus syndrome: report of a case.
Neonatal lupus syndrome (NLS) is characterized by the presence of cutaneous lupus, congenital heart block or both associated with maternal autoantibodies anti-Ro (SS-A) and anti-La (SS-B). NLS is responsible for more than 80 percent of cases with isolated congenital complete heart block. This report describes a neonate with third-degree atrioventricular block who was born to an anti-Ro (SS-A) positive mother. The dermatological and hematological manifestations of NLS were absent. The infant's clinical condition was good during the two months of follow-up with expectant management.
Gürakan
B
B
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
Yalçin
S
S
Tekinalp
G
G
Celiker
A
A
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D005260:Female; D006327:Heart Block / Q000151:congenital*; D006801:Humans; D007231:Infant, Newborn; D008178:Lupus Erythematosus, Cutaneous / Q000150:complications*
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies