title: The oesophagus and stomach of the African elephant: a histological, immunocytochemical and immunofluorescence study.
abstract: Histological, immunocytochemical and immunofluorescence methods were employed to study the oesophagus and stomach of the elephant. The histological findings were in line with the situation in monogastric species like swine and man. In the mucosa of the stomach, endocrine cells were immunoreactive to gastrin, somatostatin, chromogranin A and serotonin. Nerve cells immunoreactive to somatostatin, bombesin, VIP, PHI and CGRP were detected in the submucosal and myenteric plexus of the stomach. In the stomach, the absence of glucagon cells and the presence of endocrine cells immunoreactive to PYY, are in contrast to the situation in mammals and need further investigation. Small gastric ulcers were observed in some of the specimens.
authors.affiliation: Department of Anatomy, Potchefstroom University for Christian Higher Education, South Africa.
authors.forename: G
authors.initials: G
authors.lastname: Van Aswegen
authors.forename: J H
authors.initials: JH
authors.lastname: Schoeman
authors.forename: V
authors.initials: V
authors.lastname: De Vos
authors.forename: S
authors.initials: S
authors.lastname: Van Noorden
mesh_terms: D000818:Animals; D004606:Elephants / Q000033:anatomy & histology*; D017615:Enteric Nervous System / Q000502:physiology; D004947:Esophagus / Q000033:anatomy & histology* / Q000294:innervation; D005455:Fluorescent Antibody Technique; D007150:Immunohistochemistry; D009479:Neuropeptides / Q000032:analysis; D009490:Neurosecretory Systems / Q000502:physiology; D013270:Stomach / Q000033:anatomy & histology* / Q000294:innervation
chemical_list: D009479:Neuropeptides