title: Life-threatening Pyridium Plus intoxication: a case report.
abstract: A 16-month-old male presents with an overdose of Pyridium Plus, a combination anticholinergic, azo dye, and barbiturate, resulting in seizures, coma, and methemoglobinemia. This case report reviews the treatment of methemoglobinemia with methylene blue, activated charcoal, and exchange transfusion. Additionally, the role of the pulse oximeter is addressed when methemoglobinemia exists and is treated with methylene blue.
authors.affiliation: University of South Florida College of Medicine, Department of Pediatrics, Davis Island, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Truman
authors.forename: J J
authors.initials: JJ
authors.lastname: Dallessio
authors.forename: R E
authors.initials: RE
authors.lastname: Weibley
mesh_terms: D001285:Atropine / Q000506:poisoning*; D001463:Barbiturates / Q000008:administration & dosage / Q000506:poisoning*; D002493:Central Nervous System Diseases / Q000139:chemically induced; D002606:Charcoal / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000008:administration & dosage / Q000506:poisoning*; D004338:Drug Combinations; D062787:Drug Overdose / Q000628:therapy; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D007223:Infant; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D008751:Methylene Blue / Q000627:therapeutic use; D010092:Oximetry; D010621:Phenazopyridine / Q000008:administration & dosage / Q000506:poisoning*
chemical_list: D001463:Barbiturates; D018680:Cholinergic Antagonists; D004338:Drug Combinations; C094383:Pyridium Plus; D002606:Charcoal; D001285:Atropine; D010621:Phenazopyridine; D008751:Methylene Blue