[Analysis of antigenity of membranous labyrinth proteins of guinea pigs].
An electrophoretic dot immunobinding assay and a modified western blotting method were established. The components and antigenity of the membranous labyrinth proteins of guinea pigs were analysed. There are the same epitopes between some components of the antigen, between the antigen and extractives of acoustic nerve, cochlear nuclei, kidney and Klebsiella pneumoniae. The antigen distributes in stria vascularis, spiral ligament, spiral ganglion, the organ of Corti and Reissner's membrane etc.
Zou
J
J
PLA General Hospital, Beijing.
Zhai
S
S
Jiang
S
S
D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D015153:Blotting, Western; D003429:Cross Reactions; D007758:Ear, Inner / Q000737:chemistry / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D006168:Guinea Pigs; D008297:Male; D011817:Rabbits
D001323:Autoantibodies