[Protective effects of the stem of Berchemia racemosa Sieb. et Zucc. on experimental liver injuries].
The methanol extract and water extract from the stem of Berchemia racemosa (Rhamnaceae) showed protective effects on liver injuries induced by carbon tetrachloride (CCl4) and alpha-naphthylisothiocyanate (ANIT) in rats. The acetone extract of B. racemosa protected the liver injury induced by CCl4. One of the protective substances was identified as carpusin. Some fractions showed significant protective effects against the liver injury and cholestasis induced by ANIT.
Sato
N
N
Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan.
Ohta
S
S
Sakurai
N
N
Kamogawa
A
A
Inoue
T
T
Shinoda
M
M
D015058:1-Naphthylisothiocyanate; D000818:Animals; D002251:Carbon Tetrachloride; D056486:Chemical and Drug Induced Liver Injury; D002779:Cholestasis / Q000139:chemically induced / Q000517:prevention & control*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D008107:Liver Diseases / Q000517:prevention & control*; D008297:Male; D018547:Plant Stems / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal; D015058:1-Naphthylisothiocyanate; D002251:Carbon Tetrachloride