[Possibilities of the use of immobilized proteolytic enzyme immozymase in tuberculosis].
The paper summarises the experience gained in the use of immozymase in tuberculous patients to advance the disease diagnosis and treatment. Immozymase proved valuable in obtaining sputum enriched with M. tuberculosis in patients who were previously considered noncarriers. M. tuberculosis became detectable in 28.3% of them. Immozymase instillations of the urethra before its massage for stimulation of prostatic secretion led to getting secretion in all the patients (0.35 ml, on the average). Immuzymase inhalations were used in the treatment of purulent bronchitis in patients with destructive pulmonary tuberculosis in conservative and preoperative regimens. Postoperative immozymase inhalations promoted prevention of pleuropulmonary complications. Open treatment of the caverns with immozymase after cavernotomy shortens the treatment duration. Positive results were also reached in the treatment of pleural empyema.
Krasnov
V A
VA
Kozhevnikov
N N
NN
Beliavskiĭ
V E
VE
Potashova
V A
VA
Andrenko
A A
AA
Kul'chavenia
E V
EV
Naryshkina
S L
SL
Svistel'nik
A V
AV
Grishchenko
N G
NG
Khomiakov
V T
VT
D000280:Administration, Inhalation; D001991:Bronchitis / Q000188:drug therapy; D016724:Empyema, Pleural / Q000188:drug therapy; D004800:Enzymes, Immobilized / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D010447:Peptide Hydrolases / Q000008:administration & dosage / Q000627:therapeutic use*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D004800:Enzymes, Immobilized; D010447:Peptide Hydrolases; C072623:immozymase