S-nitrosylation of m2 muscarinic receptor thiols disrupts receptor-G-protein coupling.
Aronstam
R S
RS
Guthrie Research Institute, Sayre, Pennsylvania 18840, USA.
Martin
D C
DC
Dennison
R L
RL
Cooley
H G
HG
D000818:Animals; D003545:Cysteine / Q000502:physiology; D019204:GTP-Binding Proteins / Q000378:metabolism*; D006325:Heart Atria; D066298:In Vitro Techniques; D019832:N-Methylscopolamine; D009599:Nitroprusside / Q000494:pharmacology; D051381:Rats; D011976:Receptors, Muscarinic / Q000378:metabolism*; D012602:Scopolamine Derivatives / Q000378:metabolism; D015398:Signal Transduction
D011976:Receptors, Muscarinic; D012602:Scopolamine Derivatives; D009599:Nitroprusside; D019204:GTP-Binding Proteins; D003545:Cysteine; D019832:N-Methylscopolamine