Cutaneous angiomyxoma: a benign neoplasm distinct from cutaneous focal mucinosis.
We describe a cutaneous angiomyxoma on the head of a 38-year-old man without evidence of Carney's complex. Complete excision of the tumor appeared to be curative. Histologic examination revealed fibroblast-like cells embedded in a well-demarcated, lobulate, mucinous, and vascularized stroma with a delicate reticulin network. Immunohistologically, the stromal cells were consistently positive for vimentin and focally positive for smooth muscle A-actin but were negative for desmin, KP1, MAC387, factor XIIIa, CD34, Leu-7, and S-100. Cutaneous angiomyxoma appears to represent a myofibroblastic neoplasm that should be distinguished from cutaneous focal mucinosis.
Wilk
M
M
Department of Dermatology, University of Bonn, Germany.
Schmoeckel
C
C
Kaiser
H W
HW
Hepple
R
R
Kreysel
H W
HW
D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D017520:Mucinoses / Q000473:pathology*; D009232:Myxoma / Q000473:pathology*; D012535:Scalp; D012878:Skin Neoplasms / Q000473:pathology*