[Studies on the constituents and biological activities of simaroubaceous plants].
In search of new compounds in simaroubaceous plants, we have been investigating naturally occurring substances [alkaloids, quassinoids, limonoids and picrotoxane-type terpenoids] on the following subjects: I. chemical studies on the constituents of Japanese simaroubaceous plants (I-1 and 2), II. chemical studies on the constituents of Indonesian and Chinese simaroubaceous plants (II-1-9), III. biological activities of the isolated natural compounds mainly and the chemical modification analogs (III-1-9). This article reviews the results obtained in our laboratory since 1976 on the subjects of I, II and III.
Ohmoto
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School of Pharmaceutical Sciences, Toho University, Chiba, Japan.
D000470:Alkaloids / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008968:Molecular Conformation; D010946:Plants, Medicinal / Q000737:chemistry*
D000470:Alkaloids; D004365:Drugs, Chinese Herbal