Bacterial translocation from the gastrointestinal tract.
Bacterial translocation is defined as the passage of viable indigenous bacteria from the gastrointestinal tract to extraintestinal sites, such as the mesenteric-lymph-node complex, liver, spleen and bloodstream. Three major mechanisms promote bacterial translocation: intestinal bacterial overgrowth, deficiencies in host immune defenses and increased permeability or damage to the intestinal mucosal barrier.
Berg
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Dept of Microbiology and Immunology, Louisiana State University Medical School, Louisiana State University Medical Center-Shreveport 71130, USA.
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology / Q000382:microbiology*; D018407:Bacterial Physiological Phenomena; D002465:Cell Movement; D004064:Digestive System / Q000382:microbiology*; D007413:Intestinal Mucosa / Q000382:microbiology