title: Quantitative parameters measured by a new sonographic method for differentiation of benign and malignant breast disease.
abstract: OBJECTIVE
  To differentiate lesions on sonography by clinical amplitude/velocity reference imaging (CARI).
  
  
  METHODS
  Diameters of 144 breast lesions were measured preoperatively with a new sonographic method (CARI). This method uses mammography-identical positioning of the breast for examination and a reference structure for detection of changes of sound amplitude and velocity by through transmission of lesions. Ratios of diameters were calculated after correction for abridgement by increased velocity within some lesions. Tables were made for each ratio class containing the uncorrected craniocaudal diameter of all measurable lesions and, if present, its corresponding change of velocity (measure of elevation of the reference structure).
  
  
  RESULTS
  By retrospective analysis of the distribution of data and use of a limit to guarantee that all cancers should be detected, only 18% of the benign lesions were not distinguishable from malignant lesions.
  
  
  CONCLUSIONS
  After further technical development, CARI could be used synchronously with mammography to improve the detection and differentiation of benign and malignant breast lesions.
authors.affiliation: Strahlenabteilung, Auguste-Viktoria-Hospital, Berlin, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Richter
authors.forename: S H
authors.initials: SH
authors.lastname: Heywang-Köbrunner
mesh_terms: D001706:Biopsy; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008327:Mammography; D011300:Preoperative Care; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary / Q000295:instrumentation / Q000379:methods*