title: Fatal vascular involvement in systemic lupus erythematosus following epidermolysis bullosa acquisita.
abstract: Epidermolysis bullosa acquisita may be associated with various systemic diseases, including systemic lupus erythematosus. We describe the clinical and immunological findings in a 38-year-old women with epidermolysis bullosa acquisita and systemic lupus erythematosus. The epidermolysis bullosa acquisita preceded a dramatic flare of systemic lupus erythematosus and fatal cerebral vasculitis. If serologic evidence of lupus erythematosus develops during the course of epidermolysis bullosa acquisita, a thorough investigation is warranted to rule out potentially life-threatening systemic lupus erythematosus.
authors.affiliation: Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Yoon
authors.forename: T K
authors.initials: TK
authors.lastname: Moon
authors.forename: K H
authors.initials: KH
authors.lastname: Lee
authors.forename: S C
authors.initials: SC
authors.lastname: Kim
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001706:Biopsy; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000473:pathology; D016107:Epidermolysis Bullosa Acquisita / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D012698:Serologic Tests; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology
chemical_list: D000974:Antibodies, Antinuclear