title: Concomitant renal cell carcinoma and metastatic epithelioid angiosarcoma with microangiopathy.
abstract: Epithelioid angiosarcoma is an extremely rare clinical entity. Recognized only in recent years, epithelioid angiosarcoma mimicks epithelial tumors, both morphologically and immunohistochemically. It is very aggressive, assuming a rapid, metastatic and fatal course. This is a report of a case with an unequivocal diagnosis of epithelioid angiosarcoma and concomitant renal cell carcinoma. Reports of cancer with double origins of this combination, in patients without inherited von Hippel-Lindau disease, are extremely rare in the English literature. A review of the literature encompassing all cases of epithelioid angiosarcoma since 1983 is included.
authors.affiliation: Department of Medical Oncology, Koo Foundation, Sun Yat-Sen Cancer Center, Taipei, Taiwan, R.O.C.
authors.forename: V C
authors.initials: VC
authors.lastname: Kok
authors.forename: T W
authors.initials: TW
authors.lastname: Liu
authors.forename: H H
authors.initials: HH
authors.lastname: Lin
authors.forename: H
authors.initials: H
authors.lastname: Ou
authors.forename: S H
authors.initials: SH
authors.lastname: Cheng
authors.forename: M C
authors.initials: MC
authors.lastname: Liu
authors.forename: A T
authors.initials: AT
authors.lastname: Huang
mesh_terms: D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D005260:Female; D006394:Hemangiosarcoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary; D012186:Retroperitoneal Neoplasms / Q000150:complications / Q000473:pathology*; D014652:Vascular Diseases / Q000209:etiology*