title: [Observation of immune effect of 5 kinds of Denmark II lyophilized vaccines].
abstract: This paper reported five kinds of Denmark II lyophilized vaccines produced by 5 different biological production institutes. Through the double blind randomized trial in newborns after 1 year observation, the results demonstrated that all vaccines possessed the stability of heat tolerance and the 12 week tuberculin conversion rates of all group exceeded to 95%, and 1-year positive maintenance rates were in the range of 88.3%-96.1%, and the average diameter of induration was relatively large; the local reaction belonged to normal range; the swollen-lymph node rate was not high; the immune effect was satisfactory.
authors.affiliation: Guangzhou Institute of Tuberculosis.
authors.forename: G
authors.initials: G
authors.lastname: Lu
authors.forename: J
authors.initials: J
authors.lastname: Feng
authors.forename: J
authors.initials: J
authors.lastname: Huang
mesh_terms: D001500:BCG Vaccine / Q000276:immunology*; D002681:China; D004311:Double-Blind Method; D006801:Humans; D007231:Infant, Newborn; D014374:Tuberculin Test; D014376:Tuberculosis / Q000517:prevention & control*; D014611:Vaccination
chemical_list: D001500:BCG Vaccine