title: Sequence of the superoxide dismutase 1 (SOD 1) gene in familial Parkinson's disease.
abstract: Mutations in the superoxide dismutase 1 (SOD1) gene have been detected in affected members of some families with familial amyotrophic lateral sclerosis. To evaluate the possibility of a shared genetic defect in amyotrophic lateral sclerosis and Parkinson's disease, the SOD1 gene was sequenced in index patients with familial Parkinson's disease from 23 families. No changes were detected.
authors.affiliation: University Department of Clinical Neurology, (Neurogenetics Section), Institute of Neurology, London, UK.
authors.forename: O
authors.initials: O
authors.lastname: Bandmann
authors.forename: M B
authors.initials: MB
authors.lastname: Davis
authors.forename: C D
authors.initials: CD
authors.lastname: Marsden
authors.forename: A E
authors.initials: AE
authors.lastname: Harding
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics; D001483:Base Sequence; D004247:DNA; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D010300:Parkinson Disease / Q000235:genetics*; D013482:Superoxide Dismutase / Q000235:genetics*
chemical_list: D004247:DNA; D013482:Superoxide Dismutase