Crescentic glomerulonephritis and crystals within glomerular capillaries in an AIDS patient treated with foscarnet.
We report on a 28-year-old AIDS patient who developed a rapidly progressive glomerulonephritis while being treated with foscarnet for cytomegalovirus retinitis. Renal biopsy showed crescentic proliferation related to crystals within the glomerular capillaries. The role of foscarnet in this unusual renal syndrome is discussed.
Trolliet
P
P
Service de Néphrologie, Centre Hospitalier Lyon-Sud, France.
Dijoud
F
F
Cotte
L
L
Cahen
R
R
François
B
B
Trepo
C
C
Patricot
L M
LM
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000328:Adult; D003460:Crystallization; D017726:Cytomegalovirus Retinitis / Q000188:drug therapy*; D017245:Foscarnet / Q000009:adverse effects* / Q000627:therapeutic use; D005921:Glomerulonephritis / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male
D017245:Foscarnet