[Warm ischemia in kidney from non-heart beating donor . Instrumental evaluation].
A dramatic shortage of kidneys available for transplantation, due do the widespread reduction in consent, has urged us to explore alternative sources of kidney harvesting, in the attempt to reduce the current gap between the small number of donations and the large number of patients on waiting-list. We set our attention on non-heart-beating donors (NHBD). In the "first step" of our research, we tested an experimental technique, by using commercial pigs' kidneys, that has been useful to determinate the maximum warm ischemic time that a kidney of NHBD could tolerate. Parameters of this research were the resistance of the kidney in perfusion machine and the renal scintigraphy. Our results permitted to establish that the maximum warm ischemic time that a kidney of NHBD could tolerate, is 50 minutes (p > 0.001). This experimental technique could be employed to remove every doubt about the effective condition of NHBD kidney before the transplant, in the outlook, by using those kidneys, to reduce the organ shortage.
Leone
G
G
Istituto I Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Catania.
Puliatti
C
C
Morale
W
W
Furnari
M
M
Leone
F
F
D000818:Animals; D006358:Hot Temperature; D007511:Ischemia; D016030:Kidney Transplantation; D009926:Organ Preservation / Q000379:methods*; D013552:Swine; D013997:Time Factors