title: Clinical course after transanal advancement flap repair of perianal fistula in patients with Crohn's disease.
abstract: A total of 36 rectal advancement flap repairs were performed in 32 patients with perianal Crohn's disease. There were 12 anovaginal and 20 trans-sphincteric fistulas. Patients were followed prospectively for a mean of 19.5 months to evaluate postoperative recurrence rate. The prognostic influence of fistula type, rectal disease, intestinal disease and faecal diversion on recurrence was assessed. Four of 36 repairs showed primary failure, the operated fistula recurred in 11 patients after a median of 7 months, and a new fistula developed in six patients. The fistula recurrence rate was higher in patients with anovaginal fistula or Crohn's colitis but did not correlate with disease activity. Transitory mild incontinence of stool was observed in one patient only. Although rectal advancement flap repair does not cure perianal fistulas in most patients with Crohn's disease, those without Crohn's colitis may have long-term benefit. Short-term improvement of symptoms justifies this simple procedure even in patients with anovaginal fistula.
authors.affiliation: Department of Surgery, University of Tübingen, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Makowiec
authors.forename: E C
authors.initials: EC
authors.lastname: Jehle
authors.forename: H D
authors.initials: HD
authors.lastname: Becker
authors.forename: M
authors.initials: M
authors.lastname: Starlinger
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007902:Length of Stay; D008297:Male; D011446:Prospective Studies; D012003:Rectal Fistula / Q000503:physiopathology / Q000601:surgery*; D012008:Recurrence; D013524:Surgical Flaps; D013997:Time Factors; D014624:Vaginal Fistula / Q000503:physiopathology / Q000601:surgery*; D014945:Wound Healing