title: Dysgerminoma of the ovary with hypercalcemia associated with elevated parathyroid hormone-related protein.
abstract: The purpose of the present paper is to present a rare case of dysgerminoma of the ovary with hypercalcemia showing elevation of multiple serum tumor markers including parathyroid hormone-related protein (PTH-rP). An 18-year-old unmarried woman, with ovarian dysgerminoma showing hypercalcemia and elevated serum PTH-rP, received six courses of a combination chemotherapy consisting of bleomycin, etoposide and cisplatin after her first surgery, and had no evidence of recurrence approximately 30 months after completing the chemotherapy.
authors.affiliation: Department of Obstetrics and Gynecology, Shounan Kamakura Hospital, Kanagawa.
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: Y
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: J
authors.initials: J
authors.lastname: Hirata
authors.forename: S
authors.initials: S
authors.lastname: Wada
authors.forename: K
authors.initials: K
authors.lastname: Seki
authors.forename: I
authors.initials: I
authors.lastname: Nagata
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor / Q000097:blood*; D003131:Combined Modality Therapy; D004407:Dysgerminoma / Q000097:blood / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D009363:Neoplasm Proteins / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications* / Q000628:therapy; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; C470121:PTHLH protein, human; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins