Postoperative chemotherapy and delayed radiation in infants and very young children with choroid plexus carcinomas. The Pediatric Oncology Group.
Eight infants with choroid plexus carcinomas were treated with surgery, prolonged postoperative chemotherapy and delayed radiation. The results suggest that some infants with choroid plexus carcinomas can be successfully treated with multimodality therapy, even allowing children with less than a gross total resection to have prolonged disease-free intervals.
Duffner
P K
PK
State University of New York, Buffalo School of Medicine and Biomedical Sciences, NY, USA.
Kun
L E
LE
Burger
P C
PC
Horowitz
M E
ME
Cohen
M E
ME
Sanford
R A
RA
Krischer
J P
JP
Mulhern
R K
RK
James
H E
HE
Rekate
H L
HL
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D016545:Choroid Plexus Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D017211:Treatment Failure