Multiple sclerosis in Arabs in Jordan.
In a 2-year hospital-based study (1992 and 1993), there were 131 multiple sclerosis patients attending 2 large referral hospitals in Jordan. Based on MS/ALS case ratios an overall rate of 32.1 (95% CI 19.7-55.2) was estimated. There were 126 Arabs of whom 84 were Palestinians and 36 indigenous Jordanians. Comparison of these subgroups, which had a similar age distribution revealed that the disease was twice as frequent in Palestinians (estimated 42.0/100,000 (CI 2.8-90.8)) among Jordanians (estimated 20.0/100,000 (CI 9.5-47.2)). Clinical presentation, pattern of disease, disability and HLA association were similar to that in the disease reported in Caucasians in the West. All investigations including neurophysiology and imaging were also very similar to Western reports.
al-Din
A S
AS
Department of Biochemistry and Microbiology, Faculty of Medicine, Jordan University, Amman.
el-Khateeb
M
M
Kurdi
A
A
Mubaidin
A
A
Wriekat
A
A
al-Shehab
A
A
Khalil
R W
RW
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D018912:Arabs; D002555:Cerebrospinal Fluid / Q000166:cytology; D002648:Child; D005074:Evoked Potentials, Visual; D005260:Female; D006683:HLA-DQ Antigens / Q000097:blood; D006684:HLA-DR Antigens / Q000097:blood; D006801:Humans; D007597:Jordan / Q000453:epidemiology; D007958:Leukocyte Count; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D017678:Sex Distribution
D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens