[The significance of the hypoxic factor in adaptation to the action of ionizing radiation as a result of the accident at the Chernobyl Atomic Electric Power Station].
Data are presented from cytochemical study of the neutrophil myeloperoxidase oxygen dependent enzymes and lymphocyte succinate dehydrogenase in the peripheral blood of 2169 persons subjected to follow-ups of many kinds, at year 7 and 8 after the Chernobyl accident. By comparison with early time periods, the process of normalization of the measured values has been found to be the case, with SDG returning to normal earlier than MPO. There was an increase in the number of individuals with reduced MPO activity and stable percentage of those demonstrating increased SDG activity (30-42% versus 12%). Significance of the adaptation process in the time course of changes of the values measured is discussed along with role of hypoxic factor in adaptation to the ionizing irradiation exposure after the Chernobyl accident.
Ivashkevych
O A
OA
Kochnieva
O M
OM
Chumak
A A
AA
Bohdanovych
L V
LV
D000222:Adaptation, Physiological / Q000528:radiation effects*; D006651:Histocytochemistry; D006801:Humans; D000860:Hypoxia / Q000201:enzymology / Q000503:physiopathology*; D008214:Lymphocytes / Q000201:enzymology / Q000528:radiation effects; D009504:Neutrophils / Q000201:enzymology / Q000528:radiation effects; D009195:Peroxidase / Q000097:blood / Q000528:radiation effects; D011210:Power Plants; D018788:Radioactive Hazard Release; D013385:Succinate Dehydrogenase / Q000097:blood / Q000528:radiation effects; D013997:Time Factors; D014455:Ukraine
D009195:Peroxidase; D013385:Succinate Dehydrogenase