title: Fixed bin frequency distributions for the VNTR locus D5S110 in general United States reference databases.
abstract: Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations, and there is no evidence for association of alleles between the D5S110 and other routinely used VNTR loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in various general United States populations.
authors.affiliation: Forensic Science Research and Training Center, FBI Academy, Quantico, VA, USA.
authors.forename: B
authors.initials: B
authors.lastname: Budowle
authors.forename: A M
authors.initials: AM
authors.lastname: Giusti
mesh_terms: D044383:Black People / Q000235:genetics*; D002874:Chromosome Mapping; D016001:Confidence Intervals; D004247:DNA / Q000032:analysis*; D005787:Gene Frequency; D005828:Genetics, Population; D006630:Hispanic or Latino / Q000235:genetics*; D006801:Humans; D007256:Information Systems; D016013:Likelihood Functions; D018598:Minisatellite Repeats; D012150:Polymorphism, Restriction Fragment Length; D014481:United States; D044465:White People / Q000235:genetics*; D001741:Black or African American
chemical_list: D004247:DNA