Adherence of Candida albicans to host cells.
Research devoted to uncovering the mechanisms of adherence of Candida albicans to human tissue is reviewed. The physical aspects of adherence of the fungus to host cells and the biochemical and molecular features, as far as they are known, are discussed. Relevant pre- and post-adherence events in the pathogenesis of disease caused by this fungus are also noted. Putative adhesins and surface receptors of C. albicans for host proteins are discussed in detail.
Pendrak
M L
ML
Department of Research, Research Service, Veterans Affairs Medical Center, Kansas City, MO 64128, USA.
Klotz
S A
SA
D002176:Candida albicans / Q000472:pathogenicity / Q000502:physiology*; D002448:Cell Adhesion; D006801:Humans