Disseminated eruptive nevocellular nevi.
A 13-year-old boy suddenly developed about 2,000 dark brown to black colored papules on his face and neck and about 500 lesions on his trunk and upper extremities during a six month period. Histopathologic features were compatible with junctional nevus. The results of alpha melanocyte stimulating hormone (MSH), proliferating cell nuclear antigen (PCNA), and epidermal growth factor receptor (EGF/R) studies are presented. To the best of our knowledge, this report represents an outbreak of the highest number of nevocellular nevi in a short period without any malignant nature or evident triggering factor.
Bong
H W
HW
Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
Lee
S J
SJ
Lee
K H
KH
Chung
K Y
KY
D000293:Adolescent; D001132:Arm; D001706:Biopsy; D066246:ErbB Receptors / Q000032:analysis; D005145:Face; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009333:Neck; D009508:Nevus, Pigmented / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012878:Skin Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D014238:Trichloroacetic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D000521:alpha-MSH / Q000032:analysis
D018809:Proliferating Cell Nuclear Antigen; D000521:alpha-MSH; D014238:Trichloroacetic Acid; D066246:ErbB Receptors