title: Amyloidosis of the head and neck. A clinicopathologic study of the UCLA experience, 1955-1991.
abstract: OBJECTIVE
  To characterize the otolaryngologic manifestations of amyloidosis; classify patients with amyloidosis by specific location and type of underlying disease; and compare disease presentation and long-term outcome in these patients.
  
  
  METHODS
  Retrospective review of biopsy specimens recorded as amyloidosis.
  
  
  METHODS
  Tertiary care referral center serving a diverse patient base.
  
  
  METHODS
  Of 141 patients with biopsy-verified amyloidosis who met the inclusion criterion for the study, 27 (19%) had head and neck manifestations.
  
  
  METHODS
  Good functional outcome and survival of patients with amyloidosis.
  
  
  RESULTS
  The tongue was the most commonly affected site of the head and neck. Distinct differences exist in functional outcome and long-term survival in patients with the localized form of amyloidosis when compared with patients with systemic amyloidosis.
  
  
  CONCLUSIONS
  Because amyloidosis often affects the head and neck, otolaryngologists need to be familiar with this disease.
authors.affiliation: Division of Head and Neck Surgery, School of Medicine, University of California-Los Angeles, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Kerner
authors.forename: M B
authors.initials: MB
authors.lastname: Wang
authors.forename: G
authors.initials: G
authors.lastname: Angier
authors.forename: T C
authors.initials: TC
authors.lastname: Calcaterra
authors.forename: P H
authors.initials: PH
authors.lastname: Ward
mesh_terms: D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000473:pathology*; D001706:Biopsy; D002140:California; D005260:Female; D006257:Head / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D012189:Retrospective Studies; D012577:Schools, Medical