[Molecular therapeutic control and gene therapy approaches].
The past decade has seen the successful application of genetic techniques to the investigation of the most important phenotypes of cancer cells; for example, the identification of particular molecules on the surface of cancer cells makes it possible to target these antigens and destroy them selectively via immunotoxins. At present, gene therapy is not a new treatment modality in most instances, but rather a new technology facilitating further exploration of preexisting treatment strategies, such as immunotherapy or chemotherapy, owing to the indirect approaches of contemporary clinical application. It can be anticipated that gene transfer technology will have a considerable impact on the way certain urological anticancer strategies are pursued in the future.
Mickisch
G H
GH
Urologische Klinik, Erasmus Universität Rotterdam, Niederlande.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects; D003131:Combined Modality Therapy; D015316:Genetic Therapy; D006801:Humans; D000922:Immunotoxins / Q000009:adverse effects / Q000627:therapeutic use*; D014565:Urogenital Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*
D000922:Immunotoxins