title: [Activation of immune cells in sarcoidosis: immunopathogenic and clinical implications].
abstract: Sarcoidosis is a frequent, systemic, granulomatous disorder with predominant involvement of the hilar lymph nodes and the pulmonary parenchyma. By bronchoalveolar lavage an activation of alveolar immune cells has been observed yielding a detailed concept of the immunopathogenesis of the disease from which new, clinically applicable staging parameters are delineated.
authors.affiliation: Medizinische Klinik, Forschungsinstitut Borstel.
authors.forename: J
authors.initials: J
authors.lastname: Müller-Quernheim
mesh_terms: D016516:CD4-CD8 Ratio; D016207:Cytokines / Q000502:physiology; D006801:Humans; D008213:Lymphocyte Activation; D016676:Macrophages, Alveolar / Q000276:immunology; D011650:Pulmonary Alveoli / Q000276:immunology; D012507:Sarcoidosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D016207:Cytokines