Regulation of transcriptional elongation by RNA polymerase II.
The process of transcription is a cycle of initiation, elongation and termination steps. Initiation and elongation can be rate-limiting for RNA synthesis, and recent evidence shows that transactivators can stimulate both these steps. A stable modification of the RNA polymerase II complex is probably required to convert it from a non-processive to a processive from.
Bentley
D L
DL
Imperial Cancer Research Fund, London, UK.
D002843:Chromatin / Q000502:physiology; D010441:Peptide Chain Elongation, Translational; D011401:Promoter Regions, Genetic; D011499:Protein Processing, Post-Translational; D012319:RNA Polymerase II / Q000378:metabolism*; D013728:Terminator Regions, Genetic; D014158:Transcription, Genetic
D002843:Chromatin; D012319:RNA Polymerase II