title: Human herpesvirus-6 infection in children with first febrile seizures.
abstract: We evaluated febrile convulsions prospectively in 42 children to investigate the association between acute human herpesvirus-6 (HHV-6) infection and first-time febrile convulsions, using both virologic and serologic methods. Eight children had primary HHV-6 infection documented by viral culture and an additional three by acute- and convalescent-phase serologic studies. These findings indicate that acute HHV-6 infection is a frequent cause of febrile convulsions in young children.
authors.affiliation: Department of Pediatrics, North Shore University Hospital-Cornell University Medical College, Manhasset, NY 11030, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Barone
authors.forename: M H
authors.initials: MH
authors.lastname: Kaplan
authors.forename: L R
authors.initials: LR
authors.lastname: Krilov
mesh_terms: D000293:Adolescent; D000328:Adult; D002555:Cerebrospinal Fluid / Q000821:virology; D002648:Child; D005077:Exanthema Subitum / Q000150:complications* / Q000821:virology; D015654:Herpesvirus 6, Human / Q000302:isolation & purification*; D006801:Humans; D010033:Otitis Media / Q000150:complications; D011446:Prospective Studies; D003294:Seizures, Febrile / Q000150:complications / Q000209:etiology* / Q000821:virology