title: Influence of modified nucleosides on tRNA structure as probed by two plant nucleases.
abstract: Two new enzymatic probes have been used for structural investigations of native and unmodified transcript tRNA molecules. Both probes were single-strand-specific nucleases isolated from higher plants. The results obtained after enzymatic hydrolysis of tRNAs support the earlier hypothesis that posttranscriptional modifications in tRNA help to stabilize its structure and make it more rigid.
authors.affiliation: Institute of Biochemistry and Biophysics, PAN, Warshaw, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Przykorska
mesh_terms: D001483:Base Sequence; D005658:Fungi / Q000737:chemistry; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D010944:Plants / Q000201:enzymology; D012323:RNA Processing, Post-Transcriptional; D012343:RNA, Transfer / Q000737:chemistry* / Q000378:metabolism; D012349:RNA, Transfer, Asp / Q000737:chemistry / Q000378:metabolism; D012360:RNA, Transfer, Phe / Q000737:chemistry / Q000378:metabolism; D012263:Ribonucleosides / Q000737:chemistry*; D015719:Single-Strand Specific DNA and RNA Endonucleases / Q000378:metabolism*
chemical_list: D012349:RNA, Transfer, Asp; D012360:RNA, Transfer, Phe; D012263:Ribonucleosides; D012343:RNA, Transfer; D015719:Single-Strand Specific DNA and RNA Endonucleases