Fatal vascular involvement in systemic lupus erythematosus following epidermolysis bullosa acquisita.
Epidermolysis bullosa acquisita may be associated with various systemic diseases, including systemic lupus erythematosus. We describe the clinical and immunological findings in a 38-year-old women with epidermolysis bullosa acquisita and systemic lupus erythematosus. The epidermolysis bullosa acquisita preceded a dramatic flare of systemic lupus erythematosus and fatal cerebral vasculitis. If serologic evidence of lupus erythematosus develops during the course of epidermolysis bullosa acquisita, a thorough investigation is warranted to rule out potentially life-threatening systemic lupus erythematosus.
Yoon
J
J
Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
Moon
T K
TK
Lee
K H
KH
Kim
S C
SC
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001706:Biopsy; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000473:pathology; D016107:Epidermolysis Bullosa Acquisita / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D012698:Serologic Tests; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology
D000974:Antibodies, Antinuclear