Novel diarylsulphide derivatives as potential cytotoxic agents.
A series of diarylsulphides bearing amino, acetamido, sulphonamido, benzamido or arylideneamino synthons have been synthesized and evaluated for their antimicrobial and cytotoxic activities. Some of the tested compounds proved to possess a remarkable activity. The detailed synthesis, spectroscopic and biological data are reported.
el-Subbagh
H I
HI
Department of Medicinal chemistry, Faculty of Pharmacy, University of Mansoura, Egypt.
el-Sherbeny
M A
MA
Nasr
M N
MN
Goda
F E
FE
Badria
F A
FA
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005347:Fibroblasts / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D013440:Sulfides / Q000138:chemical synthesis* / Q000494:pharmacology
D000970:Antineoplastic Agents; D013440:Sulfides