title: Local mitomycin-C therapy in relapse-prevention of superficial bladder neoplasms treated by means of laser.
abstract: Authors report on local mitomycin-C (MTM-C) therapy applied subsequent to the treatment by means of Nd-YAG laser in 59 superficial (Ta-T1) bladder neoplasms. Relapse-rate in the neoplasms could be reduced by using MTM-C accompanied by minor side-effects. Seventy-two % of patients have been free from relapse for the mean 44-month follow-up period. Authors also suggest that laser therapy may favourably be completed by local chemoprophylaxis in "high-risk" type superficial bladder neoplasms.
authors.affiliation: Urological Ward, Central Hospital, Budapest, Hungary.
authors.forename: Z
authors.initials: Z
authors.lastname: Szemes
authors.forename: R
authors.initials: R
authors.lastname: Kovács
mesh_terms: D000328:Adult; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000517:prevention & control* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D001749:Urinary Bladder Neoplasms / Q000517:prevention & control* / Q000601:surgery*
chemical_list: D016685:Mitomycin