A displacement model for thermoluminescent dosimetry in radioimmunotherapy.
A model is developed to enable dose determination for thermoluminescent dosimeters immersed in a radioactive solution such as used in radioimmunotherapy. For low energy beta emitters used in such therapy the size of the dosimeter results in a much lower light output than when irradiated with an external Cobalt-60 (60Co) beam to the same dose as delivered to the medium. The model takes the size of the dosimeter into account and hence allows calculation of the dose in the actual medium. The application to different dosimeter sizes as well as different radionuclide energies is also illustrated. Finally, the model can be extended to dose calculation in a mixed gamma and beta irradiation geometry.
Woo
M K
MK
Department of Medical Physics, Toronto-Sunnybrook Regional Cancer Centre, Canada.
Chen
Z
Z
D001610:Beta Particles; D003037:Cobalt Radioisotopes; D006801:Humans; D007457:Iodine Radioisotopes; D008433:Mathematics; D008961:Models, Structural; D016499:Radioimmunotherapy; D013819:Thermoluminescent Dosimetry; D015021:Yttrium Radioisotopes
D003037:Cobalt Radioisotopes; D007457:Iodine Radioisotopes; D015021:Yttrium Radioisotopes