title: Nicotine therapy in patients with Alzheimer's disease.
abstract: Further studies are needed to determine the long-term effects nicotine may have in patients with Alzheimer's disease. In addition, one must consider the risks of using a chemical that is considered a health hazard to treat a patient with Alzheimer's disease. It would be beneficial to develop a compound similar to but less toxic than nicotine to study and possibly treat patients with Alzheimer's disease. Until alternatives are developed, a trial of nicotine administered transdermally may provide hope and a greater understanding of Alzheimer's disease.
authors.affiliation: University of California, San Francisco 94143, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Baldinger
authors.forename: D J
authors.initials: DJ
authors.lastname: Schroeder
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009538:Nicotine