title: Effects of drug therapy on renal function of healthy older adults.
abstract: 1. The most significant action nurses can implement to prevent renal insufficiency in older adults is to encourage an increase in fluid intake. 2. NSAIDs, including aspirin, reduce the effectiveness of virtually all anti-hypertensive drugs through their sodium retention effects, which blunt the action of the anti-hypertensive drugs. 3. People aged 60 and older are considered at increased risk for nephrotoxicity due to the decline of glomerular filtration rate with age.
authors.forename: D M
authors.initials: DM
authors.lastname: Knox
authors.forename: M T
authors.initials: MT
authors.lastname: Martof
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D004347:Drug Interactions; D005919:Glomerular Filtration Rate; D006801:Humans; D008875:Middle Aged; D051437:Renal Insufficiency / Q000139:chemically induced* / Q000451:nursing*; D014882:Water-Electrolyte Balance