Spondylarthropathy and selective IgA deficiency.
No serum IgA was detected in a young male patient suffering from spondylarthropathy (SpA) with bilateral sacroiliitis arthritis, enthesopathy and inflammatory low back pain, whose symptoms occurred in reaction to a sexually induced urethritis. After a period of several months in which the spondylarthropathy was active, disease activity came to a rest. Three years later no progression of the SpA was observed. This finding might be an indication that IgA is not involved in the pathogenesis of spondylarthropathy.
Sprenkels
S H
SH
The Netherlands Ophthalmic Research Institute, Amsterdam.
Linssen
A
A
Feltkamp
T E
TE
D000328:Adult; D016918:Arthritis, Reactive / Q000276:immunology*; D006801:Humans; D017098:IgA Deficiency / Q000150:complications*; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D013167:Spondylitis, Ankylosing / Q000276:immunology*
D007070:Immunoglobulin A