An autopsied case of T-cell rich B-cell lymphoma with general involvement.
Autoptic findings of a 77-year-old man with T-cell-rich B-cell lymphoma (TCRBCL) showed predominant infiltration of reactive T-cells with a minority population of neoplastic B-cells in liver, spleen, pancreas, adrenal gland, stomach, small intestine and heart, as well as, lymph node. DNA studies demonstrated dual rearrangement in the T-cell receptor beta (TCR beta), immunoglobulin heavy chain J region (IgJH) and kappa light chain J region (IgJ kappa) genes.
Tajima
K
K
Department of Internal Medicine, Yamagata Prefectural Kahoku Hospital.
Fukase
N
N
Shiono
T
T
Katagiri
T
T
Mito
S
S
D000368:Aged; D001706:Biopsy; D015139:Blotting, Southern; D017809:Fatal Outcome; D015329:Gene Rearrangement, T-Lymphocyte; D006801:Humans; D007144:Immunoglobulin J-Chains / Q000235:genetics*; D008198:Lymph Nodes / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000235:genetics / Q000473:pathology*; D008297:Male; D013601:T-Lymphocytes / Q000473:pathology*
D007144:Immunoglobulin J-Chains