Procedural memory and Parkinson's disease.
A detailed analysis of the mnestic deficits associated with Parkinson's disease (PD) contributes to explaining the cognitive disorders and their well documented consequences. This study was designed to show that, in PD declarative as well as procedural memory is severely impaired. Three tests designed to explore this aspect of mnestic functioning were proposed to a group of 16 parkinsonian patients whose motoricity was controlled: inverted reading, braille reading, sound form association. The results obtained, compared with those of young and aged controls, show that PD is associated with marked deficits in both declarative and procedural memory. Declarative memory impairment was similar to that observed in the control population (healthy elderly subjects, age-matched with the PD patients) but more marked in PD subjects. The procedural memory deficit was linked with age and pathology. Procedural memory involves a variety of processing modules dedicated to the type of information (visual, auditive, tactile codes). The deficits observed were more like a loss of automatism than procedural impairment stricto sensu ('knowing how'). It would be worth pursuing research by studying akinesia and motor disorders from the angle of automatic memory impairment.
Allain
H
H
Laboratoire de Pharmacologie, Faculté de Médecine, Université de Haute-Bretagne, Rennes, France.
Lieury
A
A
Quemener
V
V
Thomas
V
V
Reymann
J M
JM
Gandon
J M
JM
D000328:Adult; D017677:Age Distribution; D000368:Aged; D003071:Cognition; D006801:Humans; D008568:Memory; D008569:Memory Disorders / Q000175:diagnosis* / Q000523:psychology; D008875:Middle Aged; D008960:Models, Psychological; D010300:Parkinson Disease / Q000175:diagnosis* / Q000523:psychology; D011932:Reading; D013647:Task Performance and Analysis