title: Central venous oxygen saturation, arterial base deficit, and lactate concentration in trauma patients.
abstract: Our object was to explore the usefulness of central venous oxygen saturation, arterial base deficit, and lactate concentration in the evaluation of trauma patients. In busy urban trauma centers, limited operating room availability may necessitate that certain hemodynamically stable patients experience some delay between diagnosis of injury and surgery. Because hemodynamic compromise may occur before operation is undertaken, some means of identifying those patients who have the most severe injuries or who are at greatest risk for hemodynamic instability would be useful. We prospectively studied 40 patients with operative truncal injuries admitted to the Cook County Trauma Unit, Chicago, to examine the usefulness of postresuscitation central venous oxygen saturation (ScvO2), arterial lactate concentration, and arterial base deficit in this regard. Preoperative hypotension occurred in 12.5 per cent of these initially stable patients. ScvO2 did not significantly correlate with any of the parameters of blood loss and severity of injury examined. However, both base deficit and lactate concentration correlated with transfusion requirements; in addition, base deficit correlated with trauma score, and lactate correlated with peritoneal shed blood volume. Our data suggest that, after resuscitation, arterial base deficit and lactate concentration may be better indicators of blood loss than is ScvO2.
authors.affiliation: Cook County Trauma Unit, Chicago, Illinois 60612, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Bannon
authors.forename: C M
authors.initials: CM
authors.lastname: O'Neill
authors.forename: M
authors.initials: M
authors.lastname: Martin
authors.forename: D M
authors.initials: DM
authors.lastname: Ilstrup
authors.forename: N M
authors.initials: NM
authors.lastname: Fish
authors.forename: J
authors.initials: J
authors.lastname: Barrett
mesh_terms: D000007:Abdominal Injuries / Q000097:blood* / Q000601:surgery; D000137:Acid-Base Imbalance / Q000097:blood*; D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion; D001810:Blood Volume; D005260:Female; D006465:Hemoperitoneum / Q000097:blood; D006491:Hemothorax / Q000097:blood; D006801:Humans; D007022:Hypotension / Q000097:blood / Q000209:etiology; D015601:Injury Severity Score; D007773:Lactates / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D010490:Pericardial Effusion / Q000097:blood; D011446:Prospective Studies; D012151:Resuscitation; D012307:Risk Factors; D013898:Thoracic Injuries / Q000097:blood* / Q000601:surgery; D014680:Veins
chemical_list: D007773:Lactates; D010100:Oxygen