title: Motion artifacts in fMRI: comparison of 2DFT with PR and spiral scan methods.
abstract: Activation signals based on BOLD contrast changes consequent to neuronal stimulation typically produce cortical intensity differences of < 10% at 1.5T. Hemodynamically driven pulsation of the brain can cause highly pulsatile phase shifts, which in turn result in motion artifacts whose intensity is larger than the activation signals in 2DFT scan methods. This paper presents a theoretical and experimental comparison of the magnitude of such artifacts for 2DFT and two other methods using non-Cartesian k-space trajectories. It is shown that artifacts increase with TR for 2DFT methods, and that projection reconstruction (PR) and spiral methods have significantly reduced artifact intensities, because these trajectories collect low spatial frequencies with every view. The spiral technique is found to be superior in terms of efficiency and motion insensitivity.
authors.affiliation: Department of Diagnostic Radiology, Stanford University School of Medicine, CA 94305-5488, USA.
authors.forename: G H
authors.initials: GH
authors.lastname: Glover
authors.forename: A T
authors.initials: AT
authors.lastname: Lee
mesh_terms: D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009038:Motion