title: Enhancement of latent inhibition in rats with electrolytic lesions of the hippocampus.
abstract: Two groups of rats--1 with electrolytic lesions of the hippocampus and 1 consisting of sham-operated controls--received flavor-aversion conditioning with 2 flavors. All subjects had received prior nonreinforced exposure to Flavor A. Latent inhibition was apparent in slower acquisition of the aversion to Flavor A than to Flavor B. Hippocampal lesions had no effect on acquisition to the nonpreexposed Flavor B but produced a marked enhancement of the latent inhibition effect. The contrast between this result and previous findings of an attenuation of latent inhibition in subjects with hippocampal lesions is discussed.
authors.affiliation: Department of Psychology, University of York, England.
authors.forename: D
authors.initials: D
authors.lastname: Purves
authors.forename: C
authors.initials: C
authors.lastname: Bonardi
authors.forename: G
authors.initials: G
authors.lastname: Hall
mesh_terms: D000818:Animals; D001143:Arousal / Q000502:physiology; D001245:Association Learning / Q000502:physiology; D001288:Attention / Q000502:physiology*; D001362:Avoidance Learning / Q000502:physiology*; D001931:Brain Mapping; D003214:Conditioning, Classical / Q000502:physiology*; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D009042:Motivation; D009433:Neural Inhibition / Q000502:physiology*; D051381:Rats; D013649:Taste / Q000502:physiology*