title: [High-resolution computed tomography in the study of congenital cystic adenomatoid malformation of the lung].
abstract: Congenital cystic adenomatoid malformation of the lung is a rare condition requiring an early diagnosis and the accurate assessment of its site and extent since it can be surgically treated with excellent prognosis. This study enrolled 12 patients with suspected congenital cystic adenomatoid malformation examined with high-resolution CT (HRCT) under general anesthesia and after pulmonary hyperinsufflation, to investigate HRCT capabilities in the pathological and topographic characterization of the lesion. In 11 patients HRCT showed features suggestive of cystic adenomatoid malformation and histology confirmed the diagnosis (type I in 9 cases and type II in 2 cases). In contrast, in 1 case of extralobar pulmonary sequestration, only pathology could exclude an associated cystic adenomatoid malformation type III. In all patients HRCT assessed lesion site and extent accurately: the lesions involved only one lobe in 7 patients, whereas in the other 5 more lobes were involved, unilaterally (3/5) or bilaterally (2/5). Associated lesions were found in 6 patients (2 intralobar pulmonary sequestrations, 1 rhabdomyosarcoma, 3 pulmonary inflammations). HRCT allowed the finest anatomic structures to be identified and made it possible to acquire images without movement or reflected dysventilation, which meant better disease assessment and more correct treatment planning. In conclusion, the authors suggest HRCT in the study of cystic adenomatoid malformations and for all lung conditions in the pediatric age.
authors.affiliation: Istituto di Radiologia, Università Radiodiagnostica I, Policlinico S. Orsola, Bologna.
authors.forename: G
authors.initials: G
authors.lastname: Battista
authors.forename: G A
authors.initials: GA
authors.lastname: Turci
authors.forename: P
authors.initials: P
authors.lastname: Pisi
authors.forename: G
authors.initials: G
authors.lastname: Ghigi
authors.forename: M
authors.initials: M
authors.lastname: Zompatori
authors.forename: R
authors.initials: R
authors.lastname: Canini
mesh_terms: D000768:Anesthesia, General; D002675:Child, Preschool; D003287:Contrast Media / Q000008:administration & dosage; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media