Localization of genes for two members of the JAK family of protein tyrosine kinases to murine chromosomes 4 and 19.
Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs 1p31-3 (JAK1) and 9p24 (JAK2). The location of Jak-2 in the mouse genome extends the region of homology between mouse Chr 19 and human Chr 9.
Gough
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NM
Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Rakar
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S
Harpur
A
A
Wilks
A F
AF
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes; D008040:Genetic Linkage; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins
D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; C507904:JAK1 protein, human; C507924:JAK2 protein, human; C507905:Jak1 protein, mouse; C507926:Jak2 protein, mouse; D053613:Janus Kinase 1; D053614:Janus Kinase 2