title: [Role of ischemic cerebral infarction in the development of lethal outcomes in ruptured intracranial arterial aneurysm].
abstract: Analysis of 320 autopsy cases of death after the rupture of brain arterial aneurysms (AA) without a surgical treatment is performed. The frequency of ischemic infarction among these cases was 15.3% and in 11.2% the infarction was an immediate cause of death. The lethal outcome due to the infarction occurred at the end of the 1st and during the 2nd week with a maximum at 9-12 days. Ischemic infarction as a cause of death usually had a wide zone of spread involving 2 and more brain lobes. The thrombosis of the big brain artery was a cause of ischemic complications in 19.4% of cases. Morphological alterations of the basis cerebri in such cases consisted of changes in the intima, elastic membrane, medial layer and adventitia resulting in the lumen narrowing.
authors.forename: G P
authors.initials: GP
authors.lastname: Titova
authors.forename: V V
authors.initials: VV
authors.lastname: Krylov
authors.forename: A P
authors.initials: AP
authors.lastname: Negretskiĭ
authors.forename: A G
authors.initials: AG
authors.lastname: Zakharov
authors.forename: A V
authors.initials: AV
authors.lastname: Saenko
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000150:complications* / Q000601:surgery; D002545:Brain Ischemia / Q000209:etiology* / Q000401:mortality; D002544:Cerebral Infarction / Q000209:etiology* / Q000401:mortality; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome