The expression of ferritin on renal cancers and its relationship with cellular differentiation and tumour stage.
OBJECTIVE
To investigate ferritin expression in renal carcinoma and the correlation of expression with tumour differentiation and stage.


METHODS
Ferritin was immunohistologically detected in 35 patients (23 men and 12 women; mean age 58.2 years, range 40-82) with renal carcinoma and the findings compared with cellular type, tumour stage and the ferritin expression of a similar control population of 16 patients.


RESULTS
The incidence of ferritin expression in renal carcinomas was 51%. Expression was significantly related to tumour stage and not cellular type.


CONCLUSIONS
The results of this study re-emphasize the high expression of ferritin in renal cell carcinoma and the correlation of expression with tumour behaviour.
Yu
D S
DS
Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Yueh
K C
KC
Chang
S Y
SY
Yang
T H
TH
Ma
C P
CP
D000230:Adenocarcinoma / Q000737:chemistry* / Q000473:pathology; D018262:Adenocarcinoma, Clear Cell / Q000737:chemistry / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000737:chemistry* / Q000473:pathology; D005260:Female; D005293:Ferritins / Q000032:analysis*; D006801:Humans; D007680:Kidney Neoplasms / Q000737:chemistry* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging
D005293:Ferritins