[Mitotic index as a prognostic factor in ductal breast cancer].
150 cases of infiltrating ductal mammary carcinoma with available 8-10 years follow-up data were studied to reveal correlations between mitotic index (MI), pathological mitosis index (PMI), survival after the mastectomy, primary tumor size, histology, degree of cell polymorphism and presence of axillary metastases. It was established that the prognostic value of MI and PMI, and their correlation with other prognostic factors is determined by the stage of tumour progression and histologic type of primary tumour. There is a significant negative correlation between MI, PMI, tumour size and survival in patients surviving maximum 8 years.
Kazantseva
I A
IA
Institute of Pathology, Medical Faculty, Lunds University, Malmo, Sweden.
Potapov
Iu N
IuN
Linell'
F
F
Sternbi
N
N
D000368:Aged; D001365:Axilla; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D006801:Humans; D015409:Mastectomy, Radical; D008875:Middle Aged; D008940:Mitotic Index; D009367:Neoplasm Staging; D011110:Polymorphism, Genetic; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D015996:Survival Rate