The possible roles of sperm and sperm antibodies in the pathogenesis and treatment of AIDS.
Intravenous injections of donor sperm may possibly be of value to AIDS patients. The immunological basis for this proposal is reviewed in detail. Donor sperm introduced into the blood of a healthy patient produces anti-sperm antibodies which may become attached to the T-cells and cause their depletion. Reintroduction of donor sperm into the blood of an AIDS patient may reverse the pathogenesis by the donor sperm combining with anti-sperm antibodies so allowing the T-cells to recover. HIV is just the most common among the occupational viral infections of AIDS patients. A clinical trial is proposed.
Eldor
J
J
Theoretical Medicine Institute, Jerusalem, Israel.
D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology* / Q000628:therapy*; D000917:Antibody Formation; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D006678:HIV / Q000276:immunology / Q000472:pathogenicity*; D015658:HIV Infections / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D008954:Models, Biological; D013094:Spermatozoa / Q000276:immunology / Q000502:physiology* / Q000637:transplantation*