title: [Regional pulmonary Xenon-133 washout study using dynamic SPECT images obtained by a triple-headed SPECT system].
abstract: We investigated preliminary the clinical utility of dynamic SPECT in studying pulmonary Xenon-133 gas washout, using the continuous repetitive rotating acquisition method with a triple-headed SPECT system. The subjects included one healthy volunteer and 16 various lung diseases. After obtaining the equilibrium images, the sequential washout images were acquired every 60 sec for 6 min. As the ventilation index, the real half-time of regional activity was evaluated. With or without abnormalities on chest CT, these images allowed us to show effectively the three-dimensional distribution of ventilation abnormalities, such as peripheral or segmental air trapping.
authors.affiliation: Department of Radiology, Yamaguchi University, School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Suga
authors.forename: K
authors.initials: K
authors.lastname: Nishigauchi
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: N
authors.initials: N
authors.lastname: Kume
authors.forename: H
authors.initials: H
authors.lastname: Uchisako
authors.forename: N
authors.initials: N
authors.lastname: Matsunaga
mesh_terms: D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000378:metabolism; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000378:metabolism; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation* / Q000379:methods; D014980:Xenon Radioisotopes / Q000493:pharmacokinetics
chemical_list: D014980:Xenon Radioisotopes