[DNA level in cell nuclei of squamous cell carcinoma of the tongue and mouth floor mucosa as an indicator of the biological behavior of the tumor].
DNA was assayed in cell nuclei of squamous-cell carcinoma of the tongue (35 cases) and mucosa of the oral cavity fundus (15) using flow cytometry. The measurements were made versus size of tumor, cell differentiation stage and presence of metastasis to regional lymph nodes. Aneuploidy incidence was found to be in direct correlation with tumor size, low cell differentiation and ability to disseminate.
Rozanov
I M
IM
Bychkova
N V
NV
Korobkin
V A
VA
Chepik
O F
OF
Pozharisskiĭ
K M
KM
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000473:pathology; D002467:Cell Nucleus / Q000235:genetics; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000235:genetics* / Q000473:pathology; D011003:Ploidies; D014062:Tongue Neoplasms / Q000235:genetics
D004273:DNA, Neoplasm