Menstrual cycle-related sensitivity to 35% CO2 in panic patients.
In a double blind, random, cross-over design, 10 patients and seven controls inhaled one vital capacity of 35% CO2-65% O2 during their early-follicular and midluteal phases. Anxiety after CO2 intake was significantly stronger in the early-follicular phase than in the midluteal phase for patients. Controls had no anxiety reactions.
Perna
G
G
Department of Neuropsychiatric Sciences, University of Milan San Raffaele Hospital, Italy.
Brambilla
F
F
Arancio
C
C
Bellodi
L
L
D000280:Administration, Inhalation; D000328:Adult; D001007:Anxiety / Q000175:diagnosis / Q000503:physiopathology; D001143:Arousal / Q000502:physiology*; D002245:Carbon Dioxide; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology*; D016584:Panic Disorder / Q000175:diagnosis / Q000503:physiopathology*
D002245:Carbon Dioxide