Hypocholesterolemic activity of nut shell extract of Semecarpus anacardium (Bhilawa) in cholesterol fed rabbits.
Administration of S. anacardium nut shell extract to cholesterol fed rabbits resulted in a significant reduction in serum cholesterol (-73.3%) and serum LDL-Chol. (-80%). The extract feeding also prevented the accumulation of cholesterol/triglycerides in liver, heart muscle and aorta and caused a regression of plaques (75.3-83.5%). These results indicate that S. anacardium is hypocholesterolemic in action and prevents cholesterol induced atheroma. Possible mechanism of action is discussed.
Sharma
A
A
Department of Zoology, University of Rajasthan, Jaipur, India.
Mathur
R
R
Dixit
V P
VP
D000818:Animals; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D001161:Arteriosclerosis / Q000097:blood / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood*; D002791:Cholesterol, Dietary; D004036:Diet, Atherogenic; D008074:Lipoproteins / Q000097:blood; D008297:Male; D009754:Nuts; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011817:Rabbits
D000924:Anticholesteremic Agents; D002791:Cholesterol, Dietary; D008074:Lipoproteins; D010936:Plant Extracts; D002784:Cholesterol