Unusual clinical manifestation of a disfiguring necrobiotic granulomatous disease.
A 39-year-old woman had a disfiguring granulomatous disease of 36 years' duration. Nodules appeared on her lower extremities and later extended to her face; this led to ulceration and destruction of the nasal cartilage. This disease of unknown origin does not conform to any previously described entity. Some patients with a similar case presentation have been observed in France.
Willemsen
M
M
Department of Dermatology, Free University of Brussels, Belgium.
De Coninck
A
A
Goossens
A
A
DeCree
J
J
Roseeuw
D
D
D000328:Adult; D001706:Biopsy; D016516:CD4-CD8 Ratio; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007866:Leg; D009300:Nasal Septum; D017441:Necrobiotic Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D009666:Nose; D012867:Skin / Q000382:microbiology / Q000473:pathology