title: Dengue type 1 epidemic with haemorrhagic manifestations in Fiji, 1989-90.
abstract: A dengue type 1 epidemic occurred in Fiji between July 1989 and July 1990. Virus isolation in C6/36 cell cultures and Toxorhynchites mosquitos yielded 36 strains. Of the 3686 cases recorded by the Ministry of Health, 60% involved indigenous Fijians and 37%, Indians. A house-to-house survey revealed that a large majority of patients had classical dengue symptoms and 8% reported haemorrhagic manifestations. Among the children and adults hospitalized for dengue, 43% had haemorrhagic manifestations, including epistaxis, gingival bleeding, haematemesis, melaena and haematuria. A total of 15 patients with haemorrhagic manifestations and/or shock died, 10 of whom were aged 0-15 years; the diagnoses were confirmed in four cases by virus isolation or serology.
authors.affiliation: Department of Pathology, Faculty of Medicine, University of Papua New Guinea, Boroko.
authors.forename: A H
authors.initials: AH
authors.lastname: Fagbami
authors.forename: J U
authors.initials: JU
authors.lastname: Mataika
authors.forename: M
authors.initials: M
authors.lastname: Shrestha
authors.forename: D J
authors.initials: DJ
authors.lastname: Gubler
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks; D005260:Female; D005367:Fiji / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male