title: [Isolation of Cryptococcus neoformans from environments (pigeon excreta) in Nagasaki].
abstract: Cryptococcosis is one of the serious deep-seated mycoses in immunocompromised patients, especially those with AIDS. Cryptococcus neoformans ordinarily lives in natural environments such as soil and reproduces in pigeon excreta. It spreads in the air and infects human by inhalation. We isolated C. neoformans from pigeon excreta in hospitals, private houses, parks in Nagasaki from October to December in 1994. C. neoformans was isolated from 4 of 8 samples (50%) of pigeon excreta and the isolation rate increased to 80% (4/5) if they were weathered excreta. Two patients with pulmonary cryptococcosis occurred in the last two years in the area where C. neoformans was isolated during that period. Epidemiological studies of clinical isolates and environmental isolates are important to determine its origin of infection and the route of transmission.
authors.affiliation: Second Department of Internal Medicine, Nagasaki University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: S
authors.initials: S
authors.lastname: Kohno
authors.forename: T
authors.initials: T
authors.lastname: Noda
authors.forename: H
authors.initials: H
authors.lastname: Kakeya
authors.forename: K
authors.initials: K
authors.lastname: Yanagihara
authors.forename: H
authors.initials: H
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
authors.forename: S
authors.initials: S
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Ohtsubo
authors.forename: K
authors.initials: K
authors.lastname: Tomono
mesh_terms: D000818:Animals; D010856:Columbidae / Q000382:microbiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D004777:Environment; D005243:Feces / Q000382:microbiology*; D007564:Japan; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C