Rat phenol-preferring sulfotransferase genes (Stp and Stp2): localization to mouse chromosomes 7 and 17.
The phenol-preferring sulfotransferases aryl sulfotransferase IV and N-hydroxyarylamine sulfotransferase catalyze sulfate conjugation of N-hydroxy-2-acetylaminofluorene, a metabolite capable of causing hepatocarcinogenesis in rats. We utilized published cDNA sequences of these sulfotransferases to type the progeny of two multilocus crosses and determined that the genes, aryl sulfotransferase (Stp) and N-hydroxyarylamine sulfotransferase (Stp2), map to positions on mouse chromosomes 7 and 17.
Khan
A S
AS
Oklahoma Medical Research Foundation, Oklahoma City 73104, USA.
Taylor
B R
BR
Filie
J D
JD
Ringer
D P
DP
Kozak
C A
CA
D000818:Animals; D015239:Arylsulfotransferase / Q000235:genetics*; D001483:Base Sequence; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005796:Genes; D051379:Mice / Q000235:genetics*; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D009115:Muridae / Q000235:genetics; D051381:Rats / Q000235:genetics; D011995:Recombination, Genetic; D013045:Species Specificity; D015238:Sulfotransferases / Q000235:genetics*
C084221:St1C1 N-hydroxyarylamine sulfotransferase; D015238:Sulfotransferases; D015239:Arylsulfotransferase