title: Chromatin-mediated transcriptional repression in yeast.
abstract: Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Texas, MD Anderson Cancer Center, Houston 77005, USA.
authors.forename: S Y
authors.initials: SY
authors.lastname: Roth
mesh_terms: D002843:Chromatin / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin