[Etiologic structure of infectious complications in the urogenital tract of oncologic patients].
The investigation of the microflora of infectious complications in the urogenital tract of oncological patients showed that in spite of the similarity of the microbiotypes, the microflora of the infectious complications in the patients had marked differences. The causative agents in urological patients were mainly monocultures (69.9 per cent), whereas in gynecological patients they were mainly associations (67.2 per cent), more frequently of 2 and sometimes of 3 and even 4 or 5 taxa. The taxonomic spectra of such pathogens were also different. In the urological patients a much broader spectrum of the bacterial species with the predominance of gram-negative rod-shaped bacteria was detected. In the gynecological patients the predominating taxa were Candida spp., Staphylococcus spp., Escherichia coli and S. faecalis. The other bacteria in total amounted to 13.9 per cent. In the urological patients the predominating taxa were Pseudomonas aeruginosa, E. coli, Candida spp. and S. faecalis. The frequency of Staphylococcus spp. and Candida spp. was twice as low as that in the gynecological patients. Therefore, the comparative investigation of the causative agents in the urinary tract and female genitalia of the oncological patients revealed significant differences which cast doubt on the validity of empirical antibacterial therapy according to the principle of "above and below the waist" practiced by many physicians in the treatment of infectious complications in somatic hospitals.
Smolianskaia
A Z
AZ
Dronova
O M
OM
Dmitrieva
N V
NV
Zhabina
M I
MI
Sokolova
E N
EN
D002175:Candida / Q000302:isolation & purification; D013293:Enterococcus faecalis / Q000302:isolation & purification; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D052776:Female Urogenital Diseases / Q000382:microbiology*; D005833:Genital Neoplasms, Female / Q000150:complications*; D006801:Humans; D013045:Species Specificity; D013210:Staphylococcus / Q000302:isolation & purification