[Combined arterial and intraportal therapy of hepatocellular carcinoma: preliminary results].
Tentative results of consecutive arterial and portal chemoembolizations in 4 patients with advanced hepatoma are presented. Hepatic artery occlusion was achieved by administration of 20-60 mg adriablastin in 6-12 ml iodized oil and minced gelatin sponge. Said adriablastin-in-oil alone was used for transhepatic catheterisation and chemoembolization of portal vein 2-4 weeks later. The patients received a total of 10 courses of combined therapy, without any complication development. All the patients have been alive for 18 months and two of them have been in remission. The preliminary results of application of the new modification of transcatheter management of primary hepatoma are encouraging and make the case for undertaking prospective randomized clinical trials.
Tarazov
P G
PG
Prozorovskiĭ
K V
KV
Polysalov
V N
VN
D000293:Adolescent; D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005780:Gelatin / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D007262:Infusions, Intravenous; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D016896:Treatment Outcome
D007459:Iodized Oil; D004317:Doxorubicin; D005780:Gelatin