title: Sepsis trials. Intersection of investigation, regulation, funding, and practice.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
authors.forename: G R
authors.initials: GR
authors.lastname: Bernard
mesh_terms: D002986:Clinical Trials as Topic; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use; D004731:Endotoxins / Q000037:antagonists & inhibitors; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D008775:Methylprednisolone / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D017472:Receptors, Interleukin-1 / Q000037:antagonists & inhibitors; D012107:Research Design; D012109:Research Support as Topic; D012795:Sialoglycoproteins / Q000627:therapeutic use; D018746:Systemic Inflammatory Response Syndrome / Q000276:immunology / Q000628:therapy; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D016861:Cyclooxygenase Inhibitors; D004731:Endotoxins; C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D017472:Receptors, Interleukin-1; D012795:Sialoglycoproteins; D014409:Tumor Necrosis Factor-alpha; D008775:Methylprednisolone