[A case of chronic eosinophilic pneumonia involving IL-5 and GM-CSF].
A 57-year-old woman was admitted because of dry cough and middle-grade fever. Chest rentogenogram showed a diffuse infiltrative shadow in the right middle and lower lung fields. The symptoms disappeared after treatment with minocycline, but a new dense shadow appeared in the right upper and middle lung fields. Eosinophilic pneumonia was diagnosed from the results of bronchoalveolar lavage and transbronchial lung biopsy. The symptoms were alleviated and the infiltrative shadow was effaced after treatment with predonisolone (40 mg/day). The results of a biopsy with human eosinophils suggested that the serum and bronchoalveolar lavage fluid contained IL-5 and GM-CSF.
Momose
T
T
First Department of Internal Medicine, Shinshu University School of Medicine, Nagano, Japan.
Okubo
Y
Y
Takeda
M
M
Fujimoto
K
K
Honda
T
T
Sekiguchi
M
M
D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D002908:Chronic Disease; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000032:analysis*; D006801:Humans; D015848:Interleukin-5 / Q000032:analysis*; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy
D015848:Interleukin-5; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D011239:Prednisolone