[The incidence, prognostic factors and survival in young adults with colorectal adenocarcinoma].
The incidence of colorectal cancer is low in young patients. Because of the infrequent occurrence of this disease in those less than 40 years of age many of the published reports give conflicting results. The aim of this report is to study colorectal cancer in patients < or = 45 years old, a group rarely considered by other authors. We analyzed retrospectively the clinical features of our patients with special reference to the clinical data, personal and family history, site of lesion, and Duke's classification. Potential risk factors were analyzed for their effect on the survival of these patients. Finally, to evaluate the prognostic influence of potential risk factors and detect any interaction, a multivariate analysis was performed. We found 26 (17.2%) patients less than 45 years old with colorectal cancer. The clinical presentation, tumor site, and Duke's grade were similar in the young adult and in the general population but morbidity, mortality and postoperative complications were lower. There were no differences in resection or survival rates. Potential risk factors were no different from those of the general population.
Hidalgo Pascual
M
M
Servicio de Cirugía General, Aparato Digestivo y Trasplante de Organos Abdominales, Hospital 12 de Octubre, Madrid.
Moreno Sanz
C
C
Moreno González
E
E
Jiménez Romero
C
C
Rodríguez Romano
D
D
Manzanera Díaz
M
M
D000230:Adenocarcinoma / Q000453:epidemiology* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012307:Risk Factors