title: [Nodular pulmonary opacities caused by a severe suppurative bronchitis and bronchiectases].
abstract: METHODS
  A 67-year-old man with chronic obstructive pulmonary disease (COPD) for many years and a heavy smoker was hospitalized because of increasing dyspnoea and moderately productive cough. His general condition was clearly impaired. He was markedly cyanotic, he had a barrel-shaped chest, and there were wheezing rhonchi throughout the lung. Body temperature was 37.8 degrees C. He had mild ankle oedema. The preliminary diagnosis was exacerbation of the COPD with global respiratory failure.
  
  
  METHODS
  There was severe hypoxaemia (pO2 48 mm Hg) with hypercapnia (pCO2 46 mm Hg). Vital capacity was reduced to 1.81, one-second forced expiratory volume 0.91. Chest radiograph revealed multiple nodular opacities, such as seen in bronchial carcinoma with metastases. But computed tomography showed fluid-filled bronchi. Bronchoscopy demonstrated large amounts of dirty-white, sticky secretions as high up as the trachea, confirming the preliminary diagnosis. Klebsiella oxytoca and haemophilus influenzae were cultured from the secretions.
  
  
  METHODS
  Immediate administration of amoxycillin and clavulanic acid (2.2 g daily) quickly led to clinical improvement. Chest x-ray was normalized after 10 days. But long-term oxygen treatment was instituted because of persisting resting hypoxaemia (pO2 46 mm Hg), after which he was discharged free of dyspnoea.
  
  
  CONCLUSIONS
  To clarify nodular pulmonary opacities in a chest radiograph computed tomography should be performed before bronchoscopy.
authors.affiliation: Medizinische Klinik und Poliklinik, Universität Bonn.
authors.forename: S
authors.initials: S
authors.lastname: Ewig
authors.forename: H
authors.initials: H
authors.lastname: Müller-Miny
authors.forename: T
authors.initials: T
authors.lastname: Bauer
authors.forename: B
authors.initials: B
authors.lastname: Lüderitz
mesh_terms: D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage; D001987:Bronchiectasis / Q000000981:diagnostic imaging*; D001991:Bronchitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D007709:Klebsiella / Q000302:isolation & purification; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D013492:Suppuration; D014057:Tomography, X-Ray Computed
chemical_list: D002969:Clavulanic Acids; D019818:Clavulanic Acid; D000658:Amoxicillin