title: Impact of ultrasonographic duplex scanning on therapeutic decision making in lower-limb arterial disease.
abstract: Ultrasonographic duplex scanning has become a valuable diagnostic technique in detecting and grading stenoses and occlusions of the aortoiliac and femoropopliteal arteries. However, the question remains as to whether a treatment strategy can be designed without diagnostic angiography. This prospective study evaluated the impact of duplex scanning on therapeutic decision making. Patients with intermittent claudication, rest pain or ischaemic ulceration of the lower limb who were eligible for invasive treatment were studied. If treatment was considered necessary, a duplex scan was performed instead of diagnostic angiography. The surgeon made a therapeutic decision based on clinical assessment and information obtained from the duplex scan. If it was felt that duplex scanning gave insufficient information, diagnostic angiography was then performed. A group of 112 consecutive patients were studied prospectively; 12 were excluded for logistical reasons. The 100 remaining patients (intermittent claudication in 69, rest pain in 16, ischaemic ulceration in 15) were evaluated. Based on non-invasive tests 22 patients were treated conservatively, 36 were scheduled for percutaneous transluminal angioplasty (PTA) and 32 were scheduled for surgery. Angiography was requested to determine the definitive treatment policy in 28 patients: four of the 22 were scheduled for conservative treatment and 24 of the 32 were scheduled for surgery. All PTAs were performed without prior diagnostic angiography. Angiography was considered necessary in a further ten patients to formulate a therapeutic strategy. In 62 patients the treatment strategy could be determined without diagnostic angiography. Twenty-three of the 39 angiograms performed did not give additional information on treatment strategy. Integrated use of duplex scanning for the investigation of patients with arterial occlusive disease of the lower limb can reduce the need for diagnostic angiography.
authors.affiliation: Department of Vascular Surgery, Utrecht University Hospital, The Netherlands.
authors.forename: B H
authors.initials: BH
authors.lastname: Elsman
authors.forename: D A
authors.initials: DA
authors.lastname: Legemate
authors.forename: F H
authors.initials: FH
authors.lastname: van der Heijden
authors.forename: H J
authors.initials: HJ
authors.lastname: de Vos
authors.forename: W P
authors.initials: WP
authors.lastname: Mali
authors.forename: B C
authors.initials: BC
authors.lastname: Eikelboom
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D001161:Arteriosclerosis / Q000000981:diagnostic imaging* / Q000628:therapy; D003657:Decision Making; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000000981:diagnostic imaging* / Q000628:therapy; D007511:Ischemia / Q000000981:diagnostic imaging* / Q000628:therapy; D007866:Leg / Q000098:blood supply*; D007871:Leg Ulcer / Q000000981:diagnostic imaging* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018616:Ultrasonography, Doppler, Duplex