Early sensitization to airborne allergens.
We report the case of a 7-month-old child with failure to thrive. Celiac disease was suspected because of highly raised antigliadin IgA and IgG antibodies and subtotal villous atrophy. In peripheral blood mononuclear-cells cellular proliferation was found in response to birch pollen, rye pollen and hazelnut extract. Born in June 1992 the infant had not yet experienced a birch pollen season. He had been fed with birch pollen allergy-associated carrot, apple and potato beginning at 6 weeks of life. In the serum, specific IgG, IgM and IgA to birch pollen and profilin, rye pollen and hazelnut antigens were detectable, indicating possible in utero sensitization or T cell cross-reactivity due to early sensitization with related food antigens.
Szépfalusi
Z
Z
Department of Pediatrics, University of Vienna, Austria.
Huber
W D
WD
Ebner
C
C
Granditsch
G
G
Urbanek
R
R
D000485:Allergens / Q000276:immunology*; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D007223:Infant; D008213:Lymphocyte Activation; D008297:Male; D011058:Pollen / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000485:Allergens