title: Differential production of intracellular gamma interferon in alpha beta and gamma delta T-cell subpopulations in response to peritonitis.
abstract: Flow cytometry was used to measure T-cell intracellular gamma interferon and surface interleukin 2 re-ceptor expression in response to peritonitis in rats. Interleukin 2 receptor expression levels were similar in the two T-cell subsets, but gamma interferon production was increased fivefold in gamma delta T cells compared with pro-duction in alpha beta T cells. Our results provide further evidence of an early and vigorous gamma delta T-cell response to bac-terial infection.
authors.affiliation: Department of Surgery, University of California, Davis, USA.
authors.forename: R
authors.initials: R
authors.lastname: Berguer
authors.forename: D A
authors.initials: DA
authors.lastname: Ferrick
mesh_terms: D000818:Animals; D002432:Cecum / Q000601:surgery; D007371:Interferon-gamma / Q000096:biosynthesis*; D010538:Peritonitis / Q000276:immunology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000032:analysis; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis; D016176:T-Lymphocyte Subsets / Q000276:immunology*
chemical_list: D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta; D007371:Interferon-gamma