The outer surface lipoprotein A of Borrelia burgdorferi provides direct and indirect augmenting/co-stimulatory signals for the activation of CD4+ and CD8+ T cells.
Simon
M M
MM
Max-Planck-Institut für Immunbiologie, Freiburg, Germany.
Nerz
G
G
Kramer
M D
MD
Hurtenbach
U
U
Schaible
U E
UE
Wallich
R
R
D000818:Animals; D000954:Antigens, Surface / Q000494:pharmacology*; D001425:Bacterial Outer Membrane Proteins / Q000494:pharmacology*; D001428:Bacterial Vaccines; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D006801:Humans; D017270:Lipoprotein(a) / Q000494:pharmacology*; D008074:Lipoproteins; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D008810:Mice, Inbred C57BL
D000954:Antigens, Surface; D001425:Bacterial Outer Membrane Proteins; D001428:Bacterial Vaccines; D017270:Lipoprotein(a); D008074:Lipoproteins; C072045:OspA protein