title: The hypersensitive reaction of higher plants to viruses: a molecular approach.
abstract: The molecular basis of necrosis and localization, the two fundamental processes involved in plant hypersensitivity, are critically examined. Cell death, followed by visible necrosis, is discussed in relation to: (i) the role of wounding; (ii) the possible occurrence of signal molecules; (iii) the series of biochemical events leading to necrosis; and (iv) the events restricting the necrotic lesion within a limited area. Localization of virus infection is considered as a consequence of two events, (i) the synthesis of antiviral factors around the lesion, and (ii) the inhibition of the synthesis of the protein responsible for cell-to-cell spread of virus infection. The present knowledge, however, supplies only poor information on both the first events of cell-virus interaction and the chemical nature and role of putative signal molecules.
authors.affiliation: Institute of applied Plant Virology, C.N.R., Strada delle Cacce, Torino, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Pennazio
mesh_terms: D016923:Cell Death; D010935:Plant Diseases / Q000382:microbiology*; D010942:Plant Viruses / Q000502:physiology*; D010944:Plants / Q000821:virology*; D014779:Virus Replication