Nicotine therapy in patients with Alzheimer's disease.
Further studies are needed to determine the long-term effects nicotine may have in patients with Alzheimer's disease. In addition, one must consider the risks of using a chemical that is considered a health hazard to treat a patient with Alzheimer's disease. It would be beneficial to develop a compound similar to but less toxic than nicotine to study and possibly treat patients with Alzheimer's disease. Until alternatives are developed, a trial of nicotine administered transdermally may provide hope and a greater understanding of Alzheimer's disease.
Baldinger
S L
SL
University of California, San Francisco 94143, USA.
Schroeder
D J
DJ
D000279:Administration, Cutaneous; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage / Q000627:therapeutic use*
D009538:Nicotine