title: Spermiologic investigations before and after retrograde sclerotherapy of varicocele (preliminary communication).
abstract: A selected patient group (n = 17) with left-side varicocele was treated by retrograde sclerotherapy. Before and about six months after the treatment of varicocele the classical spermiogram, a computer aided sperm motion analysis, the acrosomal intactness, the maturity of nuclear proteins and the DNA-normality of the spermatozoa were examined. The sclerotherapy led to an increase of sperm concentration (P < 0.05), a significant improvement of sperm movement quality (P < 0.01; sperm motile efficiency and velocity straight linear), a significant increase of percentage of spermatozoa non-stainable by aniline-blue and with green fluorescence in the acridine orange test (P < 0.05). It can be concluded that the varicocele-treatment causes improvements of sperm-qualities which are not detected by the classical spermiogram.
authors.affiliation: Department of Andrology/Dermatology, University of Leipzig, Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Glander
mesh_terms: D000177:Acrosome; D000328:Adult; D004247:DNA / Q000032:analysis; D006801:Humans; D008297:Male; D009687:Nuclear Proteins / Q000032:analysis; D015911:Sclerotherapy; D013079:Sperm Maturation; D013081:Sperm Motility; D014646:Varicocele / Q000628:therapy*
chemical_list: D009687:Nuclear Proteins; D004247:DNA