title: [A mutable X(Z)-chromosome isolated from a natural population of Drosophila melanogaster].
abstract: In 1986, a mutable XZ-chromosome, in which mutation at genes yellow, white, and singed were recorded, was isolated from a natural population of Drosophila melanogaster from Zaporozh'e. Visible mutations in the region garnet-forked were also detected. Mutations appeared at a rate of about 10(-4) and were probably postmeiotic. Cytological analysis showed that two types of inversions occurred independently in XZ-chromosome. Specific features of this chromosome are hypermutability of the white locus (the mutation rate was approximately 10(-3) and a hot spot for chromosomal rearrangements in the terminal segment of the X-chromosome.
authors.forename: N N
authors.initials: NN
authors.lastname: Iurchenko
authors.forename: I K
authors.initials: IK
authors.lastname: Zakharov
mesh_terms: D000483:Alleles; D000818:Animals; D007446:Chromosome Inversion; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D006579:Heterozygote; D009154:Mutation; D012016:Reference Values; D012729:Sex Chromosome Aberrations; D014960:X Chromosome