Multimodal therapy in life-threatening cerebral lupus erythematosus: the benefit of cerebrospinal fluid pheresis.
A 27-year-old female patient with severe cerebral systemic lupus erythematosus did not respond to conventional therapy, including high-dose corticosteroids and high-dose pulsed cyclophosphamide therapy. Cerebrospinal fluid filtration (pheresis) led to rapid and lasting neurological improvement and clinical cure.
Pfausler
B
B
Department of Neurology, University of Innsbruck, Medical School, Austria.
Bösch
S
S
Grubwieser
G
G
Vollert
H
H
Greil
R
R
Hagn
C
C
Schmutzhard
E
E
D000328:Adult; D001927:Brain Diseases / Q000628:therapy*; D002555:Cerebrospinal Fluid / Q000737:chemistry*; D005260:Female; D005374:Filtration; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000628:therapy*