[Electrodermal reactivity in schizophrenic women with so-called basic symptoms].
Studies on electrodermal reactivity in a psychophysiological habituation experiment with schizophrenic patients often show a high number of "non" - or "hypo-responsiveness". There is not enough evidence to explain non-response as anticholinergic drug effect of antipsychotic medication; results in the literature suggest that hyporesponsiveness can be regarded more as a psychopathological phenomenon of a distinct subgroup of subsigns of schizophrenia which are called negative symptoms or basic disturbances. For the measurements of so-called basic symptoms we used two German self-report questionnaires, the "Frankfurter Befindlichkeitsskala für schizophren Erkrankte (FBS)" by Süllwold and Herrlich (1987) and the "Günzburger Selbstbeurteilungsskala für Basissymptome bei Schizophrenen (GSBS)" by Schüttler and co-workers (Blumenthal et al., 1989). The FBS includes two factors, a so-called "hyper" - and a "hypo"-syndrome; the GSBS consists of three categories which are named "Potential-reduktion", "kognitive Denkstörungen" and "kognitive Wahrnehmungsstörungen". We expected a relationship between "non" - oder "hypo-responsiveness" of the electrodermal reactivity in a habituation experiment with acoustic stimuli and higher values in the "FBS hypo-syndrome" respectively the "GSBS Potentialreduktion" (reduction of energy, drive, apathy, depressive mood etc.). 40 female inpatients, mean age 35.5 years with the ICD-9 diagnoses 295.x (n = 34) and 397.0 (n = 6) were investigated in this study. All the inpatients were treated with antipsychotic medication at the time of the study (usually the third week of inpatient stay in a closed acute treatment ward for females after reduction of acute psychopathology).(ABSTRACT TRUNCATED AT 250 WORDS)
Wolfersdorf
M
M
Abteilung Psychiatrie I, Universität Ulm.
Straub
R
R
Barg
T
T
Studemund
H
H
Ruppe
A
A
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001143:Arousal / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005712:Galvanic Skin Response / Q000187:drug effects / Q000502:physiology*; D006185:Habituation, Psychophysiologic / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D012565:Schizophrenic Psychology
D014150:Antipsychotic Agents