Juvenile scleroderma: report of a case.
Scleroderma is a rare connective tissue disease in children. A 12-year-old boy suffered from progressive increasing skin tension with erythematous changes in his left leg for a period of 3 months. This limited the range of motion in his left first and second metatarsophalangeal joints. A skin biopsy showed hypertrophic collagen bundles with atrophic skin appendages and lymphocytic infiltration. Based on the clinical manifestations and typical histopathologic findings, juvenile linear scleroderma was diagnosed. He was successfully treated with a short course of oral prednisolone in addition to long-term therapy with D-penicillamine and a topical emollient.
Chan
W C
WC
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan R.O.C.
Shyur
S D
SD
Sy
L B
LB
Lin
Y N
YN
D002648:Child; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D010396:Penicillamine / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D012594:Scleroderma, Localized / Q000188:drug therapy / Q000473:pathology*; D012867:Skin / Q000473:pathology
D011239:Prednisolone; D010396:Penicillamine