title: [Oral administration of itraconazole in a case of neonatal hepatic candidiasis].
abstract: Systemic Candida A. infections are increasing in Neonatal Intensive Care Units. For many years, Amphotericin B, alone or in combination with 5-fluorocytosine, have been used. Recently a search for new and less toxic drugs has been started. In this study we report the case of hepatic candidosis in a preterm newborn. The patient has been treated with itraconazole, an oral antifungal agent with broad spectrum activity. Its tolerance has been good. No severe side effects were observed and biochemical parameters showed no consistent drug induced effects.
authors.affiliation: Clinica Pediatrica I, Università di Catania, Italia.
authors.forename: A
authors.initials: A
authors.lastname: Sciacca
authors.forename: P
authors.initials: P
authors.lastname: Betta
authors.forename: S
authors.initials: S
authors.lastname: Cilauro
authors.forename: A
authors.initials: A
authors.lastname: Saporito
authors.forename: L G
authors.initials: LG
authors.lastname: Tina
mesh_terms: D000284:Administration, Oral; D002177:Candidiasis / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy / Q000382:microbiology*; D007363:Intensive Care Units, Neonatal; D007558:Italy; D017964:Itraconazole / Q000008:administration & dosage*; D008107:Liver Diseases / Q000188:drug therapy / Q000382:microbiology*; D008297:Male
chemical_list: D017964:Itraconazole