Two classes of cortical neurones labelled with Vicia villosa lectin in the guinea-pig.
Cell surface substance(s) containing terminal N-acetylgalactosamine (GaINAc) was localized in the cerebral cortex of the guinea-pig. Vicia villosa and Glycine max, both specific to GaINAc, labelled the surface of the cell body of multipolar and triangular neurones. The labelling extended to the apical dendrite and axon initial segment in the triangular neurones. They were distributed exclusively in layer 5. Most of the labelled multipolar neurones contained a calcium-binding protein, parvalbumin (Pv), while none of the triangular neurones did. The findings indicate that, in the guinea-pig, pyramidal neurones as well as non-pyramidal interneurones are enwrapped by GaINAc-containing substances and suggest that this enwrapping does not seem to be linked to Pv production.
Ojima
H
H
1st Department of Anatomy, Toho University School of Medicine, Tokyo, Japan.
Kuroda
M
M
Ohyama
J
J
Kishi
K
K
D000375:Aging / Q000378:metabolism*; D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007150:Immunohistochemistry; D007395:Interneurons / Q000737:chemistry*; D037102:Lectins; D008297:Male; D037121:Plant Lectins; D017966:Pyramidal Cells / Q000737:chemistry*
D037102:Lectins; D037121:Plant Lectins; C042242:Vicia lectins