Renal transplant thrombosis in children.
Data concerning 100 consecutive renal transplantations in children were analyzed to determine factors enhancing the risk of renal transplant thrombosis. The incidence of renal transplant thrombosis was high, at 12%. It is concluded that in addition to young age and low body weight of recipient and young age of the donor, also a high preoperative urine production contributes to the occurrence of thrombosis. Children with hypoplastic or dysplastic kidneys are at greater risk for thrombosis. Considering the influence of high urine production of the native kidneys, it may be possible to prevent thrombosis by albumin and ample fluid administration.
van Lieburg
A F
AF
Department of Pediatrics, St. Radboud University Hospital, Nijmegen, The Netherlands.
de Jong
M C
MC
Hoitsma
A J
AJ
Buskens
F G
FG
Schröder
C H
CH
Monnens
L A
LA
D000367:Age Factors; D000418:Albumins / Q000627:therapeutic use; D001835:Body Weight; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005440:Fluid Therapy; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D015994:Incidence; D007668:Kidney / Q000002:abnormalities; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D012078:Renal Artery Obstruction / Q000453:epidemiology* / Q000517:prevention & control; D012082:Renal Veins; D012189:Retrospective Studies; D012307:Risk Factors; D013927:Thrombosis / Q000453:epidemiology* / Q000517:prevention & control; D014019:Tissue Donors
D000418:Albumins