The spectrum of ankylosing spondylitis.
Sacroiliac involvement is an early hallmark, but even so, patients with ankylosing spondylitis present a remarkable spectrum of disease. Research probing associations among spondylitis, enteric bacterial infection, and host expression of HLA-B27 may offer etiologic clues and point the way to disease-specific therapies.
Harley
J B
JB
Endocrinology and Metabolism Section, University of Oklahoma Health Sciences Center, USA.
Scofield
R H
RH
D000293:Adolescent; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005081:Exercise Therapy; D005260:Female; D015796:HLA-B27 Antigen / Q000097:blood; D006801:Humans; D008297:Male; D012446:Sacroiliac Joint; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D012460:Sulfasalazine / Q000008:administration & dosage
D000894:Anti-Inflammatory Agents, Non-Steroidal; D015796:HLA-B27 Antigen; D012460:Sulfasalazine