title: [Problems of rational chemotherapy and the role of cefmetazole in their solution].
abstract: The paper presents an analysis of the most actual problems of modern antibacterial chemotherapy: mechanisms and distribution of resistance in the most significant clinical gram-positive and gram-negative organisms. Approaches to their solution based on the use of cefmetazole and other cephamycins are indicated.
authors.forename: T
authors.initials: T
authors.lastname: Iokota
mesh_terms: D002437:Cefazolin / Q000009:adverse effects / Q000627:therapeutic use; D015311:Cefmetazole / Q000009:adverse effects / Q000627:therapeutic use*; D018550:Cephalosporin Resistance; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D015311:Cefmetazole; D002437:Cefazolin