title: Antifungal agents: an overview. Part II.
abstract: The recent introduction of a new generation of antifungal drugs promises to alter significantly therapy for both systemic and superficial mycoses, in particular, onychomycosis. This article presents an in-depth review of the azoles (the triazoles itraconazole and fluconazole), the allylamines (naftifine and terbinafine), and the morpholine derivative amorolfine.
authors.affiliation: Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
authors.forename: A K
authors.initials: AK
authors.lastname: Gupta
authors.forename: D N
authors.initials: DN
authors.lastname: Sauder
authors.forename: N H
authors.initials: NH
authors.lastname: Shear
mesh_terms: D000499:Allylamine / Q000031:analogs & derivatives / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use; D000935:Antifungal Agents / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001393:Azoles / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use; D003881:Dermatomycoses / Q000188:drug therapy; D006801:Humans; D009025:Morpholines / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use; D009281:Naphthalenes / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use; D014009:Onychomycosis / Q000188:drug therapy; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D009025:Morpholines; D009281:Naphthalenes; D000499:Allylamine; C029178:naftifine; C038974:amorolfine; D000077291:Terbinafine