title: Bilateral breast cancer: early detection with mammography.
abstract: OBJECTIVE
  To assess the contribution of mammography in the detection of cancer in the contralateral breast in women with bilateral breast cancer.
  
  
  METHODS
  Mammograms and clinical records of 77 patients with bilateral breast cancer were reviewed in a retrospective study.
  
  
  RESULTS
  The contralateral cancer was detected at mammography in 68 of 77 patients (88%) and identified at mammography alone in 50 patients (65%). No statistically significant differences in either mammographic detection rates or stage of the contralateral cancer were noted in patients younger than 50 years (n = 25) compared with those 50 years of age or older (n = 52). Cancers detected at annual screening mammography were of lower stage than cancers in unscreened patients. In the screened group, 41% of tumors were ductal carcinoma in situ alone and 23% were stage II or III, compared with 22% and 50%, respectively, in the unscreened group.
  
  
  CONCLUSIONS
  Mammographic examination and follow-up in patients with unilateral breast cancer allow detection of the majority of contralateral breast cancers and earlier stage cancers.
authors.affiliation: Department of Radiology/TC2910, University of Michigan Hospital, Ann Arbor 48109-0326, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Roubidoux
authors.forename: M A
authors.initials: MA
authors.lastname: Helvie
authors.forename: N E
authors.initials: NE
authors.lastname: Lai
authors.forename: C
authors.initials: C
authors.lastname: Paramagul
mesh_terms: D000367:Age Factors; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000517:prevention & control; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008327:Mammography / Q000706:statistics & numerical data; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000453:epidemiology; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000453:epidemiology; D010808:Physical Examination; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors