Molecular typing and haplotypic associations of HLA-B*44 subtypes.
The heterogeneity of HLA-B44 is confirmed and the sequence difference between the two major subtypes, B*4402, *4403, is attributed to one polymorphic site in the third exon. A method is described to discriminate B*4402 and B*4403, and the occurrence and linkage disequilibrium of B*44 subtypes is discussed. No example of B*4401 polymorphism in exon 2 was observed.
Varney
M D
MD
Tissue Typing Laboratory, Royal Melbourne Hospital, Australia.
Boyle
A J
AJ
Tait
B D
BD
D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D005805:Genes, MHC Class I; D015235:HLA-B Antigens / Q000145:classification / Q000235:genetics*; D059948:HLA-B44 Antigen; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
D015235:HLA-B Antigens; D059948:HLA-B44 Antigen