title: Epstein-Barr virus lymphoproliferative disease of donor origin after kidney transplantation: a case report.
abstract: A case of an Epstein-Barr virus (EBV)-associated B lymphoproliferative disorder presented as a renal transplant obstruction is reported. The diagnosis was made from histology, immunohistochemistry, and EBV expression studies. Cytogenetic analysis showed the tumor to be of donor origin and revealed chromosomal translocation 46, XY, inv (1)(p35; q41), involving the EBV insertion site 1(1p35) and transforming growth factor beta 2(1q41) loci.
authors.affiliation: Division of Nephrology, Hôpital de Brabois, University of Nancy, France.
authors.forename: E
authors.initials: E
authors.lastname: Renoult
authors.forename: B
authors.initials: B
authors.lastname: Aymard
authors.forename: M J
authors.initials: MJ
authors.lastname: Grégoire
authors.forename: A
authors.initials: A
authors.lastname: Bellou
authors.forename: J
authors.initials: J
authors.lastname: Hubert
authors.forename: D
authors.initials: D
authors.lastname: Hestin
authors.forename: J
authors.initials: J
authors.lastname: Audouin
authors.forename: P
authors.initials: P
authors.lastname: Lederlin
authors.forename: M
authors.initials: M
authors.lastname: Kessler
mesh_terms: D000368:Aged; D001402:B-Lymphocytes; D007446:Chromosome Inversion; D002878:Chromosomes, Human, Pair 1; D004251:DNA Transposable Elements / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D006566:Herpesviridae Infections / Q000235:genetics / Q000635:transmission* / Q000821:virology; D004854:Herpesvirus 4, Human / Q000235:genetics; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000209:etiology* / Q000235:genetics / Q000821:virology; D014019:Tissue Donors; D016212:Transforming Growth Factor beta / Q000235:genetics; D014412:Tumor Virus Infections / Q000235:genetics / Q000635:transmission* / Q000821:virology
chemical_list: D004251:DNA Transposable Elements; D004279:DNA, Viral; D016212:Transforming Growth Factor beta