[Hyperglycemia in toxic oil syndrome].
OBJECTIVE
To know the prevalence of hyperglycemia in patients with Spanish toxic oil syndrome (TOS). To analyze clinical, biochemical, and pathological associated factors. To compare them with a control group.


METHODS
Case and controls study.


METHODS
Primary Health Care. XI Sanitary district in Madrid.


METHODS
734 cases with toxic oil syndrome. 1474 control subjects.


RESULTS
Prevalence of impaired glucose tolerance was 2.95% in TOS and 0.07% in control subjects (p < 0.001; OR, 7.55; IC, 291-19.57). Diabetes No insulin treated was 7.78% in TOS and 3.26% in controls (p < 0.001; OR 250; IC 1.62-3.87). Diabetes insulin treated was 1.99% in TOS and 0.47% in controls (p < 0.01; OR, 4.98; IC, 1.80-13.78). Prevalence of diabetes mellitus in TOS was 9.77 and 3.67% (p < 0.001; OR, 2.85; IC, 1.90-4.25) in controls. The pancreatic lesions found in the necropsies were vasculitis type TOS (4 cases) and endothelial vascular lesions (1 case).


CONCLUSIONS
The prevalence of hyperglycemia in TOS reached 13%, where as in the control subjects, it was 3.8% (p < 0.001). The pancreatic lesions detected in deceased TOS patients did not coincide with those commonly described in diabetes mellitus.
Sáenz Calvo
A
A
Centro de Salud Gómez Acebo. Insalud Area/Sector 11 de Madrid.
García del Valle
M
M
Cordón Rodríguez
E
E
Izquierdo Martínez
M
M
Ausejo Segura
M
M
Rojas Hidalgo
E
E
D000328:Adult; D001937:Brassica; D016022:Case-Control Studies; D004042:Dietary Fats, Unsaturated / Q000009:adverse effects*; D005229:Fatty Acids, Monounsaturated; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010938:Plant Oils / Q000506:poisoning*; D015995:Prevalence; D000074262:Rapeseed Oil; D013577:Syndrome
D004042:Dietary Fats, Unsaturated; D005229:Fatty Acids, Monounsaturated; D010938:Plant Oils; D000074262:Rapeseed Oil