Chromatin-mediated transcriptional repression in yeast.
Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.
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Department of Biochemistry and Molecular Biology, University of Texas, MD Anderson Cancer Center, Houston 77005, USA.
D002843:Chromatin / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014158:Transcription, Genetic
D002843:Chromatin