title: Assessing the contribution of anaerobic microflora of the tongue to oral malodor.
abstract: Research suggests that the tongue plays an important role in the production of oral malodor. To investigate the role of tongue surface characteristics and oral bacteria in halitosis development, the authors tested associations between odor measurements, volatile sulfur compound levels, periodontal parameters, tongue surface characteristics, presence of trypsinlike activity of organisms on the tongue and teeth and bacteriological parameters in 16 participants with complaints of oral malodor. The data indicate that the proteolytic, anaerobic flora residing on the tongue plays an essential role in the development of halitosis.
authors.affiliation: Department of Biologic Materials Sciences, University of Michigan, Ann Arbor, USA.
authors.forename: E H
authors.initials: EH
authors.lastname: De Boever
authors.forename: W J
authors.initials: WJ
authors.lastname: Loesche
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000494:pharmacology / Q000627:therapeutic use*; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000378:metabolism / Q000472:pathogenicity*; D001587:Benzoylarginine-2-Naphthylamide; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D002940:Circadian Rhythm; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D006209:Halitosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000494:pharmacology / Q000627:therapeutic use; D013440:Sulfides / Q000378:metabolism; D011795:Surveys and Questionnaires; D014059:Tongue / Q000382:microbiology*; D014357:Trypsin / Q000378:metabolism
chemical_list: D000891:Anti-Infective Agents, Local; D009067:Mouthwashes; D013440:Sulfides; D001587:Benzoylarginine-2-Naphthylamide; D014357:Trypsin; C010882:chlorhexidine gluconate; D002710:Chlorhexidine