title: Vegetable and animal products as determinants of colon cancer risk in Dutch men and women.
abstract: To examine the relationship between colon cancer and food groups from vegetable or animal sources and their possible interactions with gender, we analyzed data from a Dutch case-control study. Dietary patterns were assessed for 232 colon cancer cases and 259 population controls. In multivariate analyses, the consumption of vegetables was associated significantly with reduced colon-cancer risk (odds ratio [OR] for highest cf lowest quartile of consumption = 0.4, 95 percent confidence interval [CI] = 0.2-0.7, P-trend = 0.0004). Consumption of fresh red meat was associated positively with risk in women (OR = 2.4, 95% CI = 1.0-5.7, P-trend = 0.04), especially for those with a high consumption of red meat relative to the consumption of vegetables and fruits (OR = 3.1). For men, no association with consumption of fresh red meat was found (OR = 0.9). No clear associations were found for other products of vegetable or animal origin. The results of this Dutch case-control study support the preventive potential of a high-vegetable diet in colon cancer risk. This study suggest this may be important for women consuming a diet high in red meat.
authors.affiliation: TNO Nutrition and Food Research Institute, Zeist, The Netherlands.
authors.forename: E
authors.initials: E
authors.lastname: Kampman
authors.forename: D
authors.initials: D
authors.lastname: Verhoeven
authors.forename: L
authors.initials: L
authors.lastname: Sloots
authors.forename: P
authors.initials: P
authors.lastname: van 't Veer
mesh_terms: D000368:Aged; D000818:Animals; D016022:Case-Control Studies; D003110:Colonic Neoplasms / Q000453:epidemiology*; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D005502:Food; D005638:Fruit; D006801:Humans; D008019:Life Style; D008297:Male; D008460:Meat; D008875:Middle Aged; D015999:Multivariate Analysis; D009426:Netherlands / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D014675:Vegetables; D014815:Vitamins / Q000008:administration & dosage
chemical_list: D014815:Vitamins