Dysembryoplastic neuroepithelial tumour of the cerebellum.
A case of dysembryoplastic neuroepithelial tumour of the cerebellum occurring in a 28-year-old woman is presented. The lesion extended from the cortex of the inferior vermis upwards into the white matter. Histologically, it exhibited areas of microcystic cerebellar astrocytoma and glial regions with hamartomatous blood vessels as well as areas with oligodendrocyte-like cells (OLC) with a delicate, fibrillary stroma lying in a mucinous, often microcystic matrix. The OLC showed prominent rosette formation and immunohistochemical features suggesting neuronal, i.e. granule cell, differentiation.
Kuchelmeister
K
K
Institut für Neuropathologie der Universität, Münster, Germany.
Demirel
T
T
Schlörer
E
E
Bergmann
M
M
Gullotta
F
F
D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology; D002454:Cell Differentiation; D002528:Cerebellar Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D018302:Neoplasms, Neuroepithelial / Q000473:pathology*; D016900:Neurofilament Proteins / Q000276:immunology
D000911:Antibodies, Monoclonal; D016900:Neurofilament Proteins