Enamel hypoplasia secondary to candidiasis endocrinopathy syndrome: case report.
The clinical features of a 7-year-old girl with enamel hypoplasia secondary to autoimmune hypoparathyroidism and chronic mucocutaneous candidiasis are detailed. The combination of features are typical of a rare, probably genetically determined immunodeficiency termed candidiasis endocrinopathy syndrome (CES). Affected individuals have chronic mucocutaneous candidiasis and a spectrum of autoimmune endocrinopathies, including hypoparathyroidism, adrenocortical hypofunction, and diabetes mellitus. Treatment includes long-term management of the candidal infection and correction of any associated endocrinopathy.
Porter
S R
SR
Department of Oral Medicine, Eastman Dental Institute, London.
Eveson
J W
JW
Scully
C
C
D002178:Candidiasis, Chronic Mucocutaneous / Q000150:complications*; D002648:Child; D003744:Dental Enamel Hypoplasia / Q000209:etiology*; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications*; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications*; D013577:Syndrome