Standard reference materials and data quality assurance: the lesson from the analysis of trace elements.
The problem of having accurate and precise analytical data of the concentrations of trace elements and compounds in bioclinical studies is of fundamental importance. This can be conveniently faced if appropriate standard reference materials, with known concentrations of the analyte object of study, are available. This paper reviews the present situation of these standard materials in the field of trace element analysis in biological specimens. The most important requirements in the preparation and in the application of these materials are presented and discussed.
Gallorini
M
M
CNR Centro di Radiochimica e Analisi per Attivazione, Università di Pavia, Italy.
D005069:Evaluation Studies as Topic; D006801:Humans; D011786:Quality Control; D012015:Reference Standards; D014131:Trace Elements / Q000592:standards*
D014131:Trace Elements