title: Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study.
abstract: BACKGROUND
  Diabetes affects the vascular ocular circulation. Colour Doppler imaging allows for simultaneous two dimensional anatomical imaging and Doppler evaluation of blood flow velocity; with this technique ocular blood flow velocity can be evaluated in normal and diabetic patients.
  
  
  METHODS
  A prospective study compared blood flow velocity in ocular vessels (ophthalmic artery, posterior ciliary arteries, central retinal vessels, and vortex veins) of 25 patients with proliferative diabetic retinopathy and 30 age matched normal subjects using a colour Doppler imaging unit (Toshiba Sonolayer SSA-270 A with a 5.0 MHz PLF-503 ST phased array scanning head).
  
  
  RESULTS
  The diabetic patients had lower blood velocities than the volunteers. There were significant differences in ophthalmic artery; systolic (p < 0.01), diastolic (p < 0.001), mean velocity (p < 0.05), and central retinal artery; systolic (p < 0.001), diastolic (p < 0.001), mean velocity (p < 0.05). No significant correlations were found between age and blood velocities.
  
  
  CONCLUSIONS
  Ocular blood flow velocity was decreased in diabetic patients with proliferative diabetic retinopathy.
authors.affiliation: Ramón y Cajal Hospital, Department of Ophthalmology, Alcalá de Henares University, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Mendívil
authors.forename: V
authors.initials: V
authors.lastname: Cuartero
authors.forename: M P
authors.initials: MP
authors.lastname: Mendívil
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D003930:Diabetic Retinopathy / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005123:Eye / Q000098:blood supply*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging; D011446:Prospective Studies; D012171:Retinal Vessels / Q000000981:diagnostic imaging; D018615:Ultrasonography, Doppler, Color