[Central mechanisms of neurogenic gastric lesion and its pharmacologic correction].
The study was undertaken to study the central mechanisms responsible for the development of neurogenic gastric lesion caused by a concurrent action of immobilization and 3-hour electrostimulation. With this action, there was a reduction in the levels of norepinephrine, dopamine, and GABA and impaired energy formation processes in brain tissue. Prior administration of L-DOPA, aethimizolum, phenibutum, and piracetam prevented changes in neurotransmitter balance and nerve tissue energy exchange. The drugs under study had positive preventive and therapeutical effects in experimental gastric lesions.
Bul'on
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D000818:Animals; D004558:Electric Stimulation; D007031:Hypothalamus / Q000503:physiopathology*; D008297:Male; D051381:Rats; D013272:Stomach Diseases / Q000188:drug therapy* / Q000209:etiology