title: Antimicrobial potentials of some plant species of the Bignoniaceae family.
abstract: The methanol extracts of the leaves and stem bark of four Bignoniaceae plants Jacaranda mimosifolia D. Dol., Tecoma stans Linn., Tabebuia rosea (Bertol) D.C., and Crescentia cujete Linn. were studied for their antimicrobial activity using a wide range of Gram-positive and Gram-negative bacteria and fungi. Extracts of both the leaves and stem bark of majority of plant species studied showed variable but remarkable broad spectrum antimicrobial activity. However, methanol extracts of Tecoma stans leaves was found to be effective against only Candida albicans at the concentrations employed. It was observed that the extracts of stem bark generally showed better antimicrobial activity than those of the leaves and some organisms were selectively more sensitive to the extracts than others. Preliminary phytochemical screening of these plants revealed the presence of tannins, flavonoids, alkaloids, quinones and traces of saponins. The antimicrobial activity observed are discussed in relation to the chemical constituents reportedly isolated from these plants and their traditional uses.
authors.affiliation: Department of Pharmacognosy, College of Medicine, University of Ibadan, Nigeria.
authors.forename: O A
authors.initials: OA
authors.lastname: Binutu
authors.forename: B A
authors.initials: BA
authors.lastname: Lajubutu
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D016488:Medicine, African Traditional; D008826:Microbial Sensitivity Tests; D009549:Nigeria; D010946:Plants, Medicinal / Q000502:physiology*