title: [Errors and risks in administration of nasal respiratory therapy of obstructive sleep apnea].
abstract: Over a period of 1 year we observed in our sleep laboratory in 502 patients with sleep related breathing disorders several side effects of positive airway pressure treatment, furthermore we observed in 5 patients unexpected dangerous complications due to the application of CPAP and BIPAP. We observed mask leakages which lead to insufficient positive airway pressure-therapy and an occurence of short central apnoeas during NREM sleep after arousal or wakefulness periods. Finally we observed in 5 patients during treatment with CPAP and BIPAP an unexpected appearance of long central apnoeas up to 110s and central hypoventilations up to 5 min accompanied by excessive hypoxaemia (SaO2 < 20%) and cardiac arrhythmias. We conclude that in the treatment of obstructive sleep apnoeas we have to expect in 1-2% complications of the positive airway pressure treatment itself. To avoid life endangered complications the first night application should be done only in conventional sleep laboratories.
authors.affiliation: Zentrum für Innere Medizin, Philipps-Universität Marburg.
authors.forename: A
authors.initials: A
authors.lastname: Stammnitz
authors.forename: H
authors.initials: H
authors.lastname: Becker
authors.forename: H
authors.initials: H
authors.lastname: Schneider
authors.forename: J H
authors.initials: JH
authors.lastname: Peter
authors.forename: P
authors.initials: P
authors.lastname: Wichert
mesh_terms: D004868:Equipment Failure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D011175:Positive-Pressure Respiration / Q000009:adverse effects*; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000209:etiology / Q000628:therapy*
chemical_list: D010100:Oxygen