title: Cu,Zn SOD in German families with ALS.
abstract: We studied the gene for Cu,Zn SOD in 15 German patients with familial ALS and did not find any mutation. Activity of the enzyme and its expression at the protein level was also normal in each patient and in 18 patients suffering from the sporadic form of ALS.
authors.affiliation: Department of Neurology, Charité, Humboldt University, Berlin, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Bachus
authors.forename: A
authors.initials: A
authors.lastname: Claus
authors.forename: D
authors.initials: D
authors.lastname: Megow
authors.forename: J
authors.initials: J
authors.lastname: Brockmöller
authors.forename: T
authors.initials: T
authors.lastname: Porstmann
authors.forename: C A
authors.initials: CA
authors.lastname: Gericke
authors.forename: M
authors.initials: M
authors.lastname: Riepe
authors.forename: G
authors.initials: G
authors.lastname: Küther
authors.forename: S
authors.initials: S
authors.lastname: Zierz
authors.forename: A C
authors.initials: AC
authors.lastname: Ludolph
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000201:enzymology* / Q000235:genetics; D001483:Base Sequence; D005091:Exons / Q000502:physiology; D005858:Germany; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism*
chemical_list: D013482:Superoxide Dismutase