title: Necrotizing (malignant) external otitis: prospective comparison of CT and MR imaging in diagnosis and follow-up.
abstract: OBJECTIVE
  To compare computed tomography (CT) and magnetic resonance (MR) imaging in the diagnosis and follow-up of necrotizing external otitis.
  
  
  METHODS
  CT and MR imaging were performed in seven patients at diagnosis and at 6 and 12 months after initiation of therapy. Imaging findings were compared and correlated with the clinical course of the disease.
  
  
  RESULTS
  Cortical bone erosion was best seen on CT scans (n = 5 vs n = 0 on MR images) and failed to normalize with cure. Subtemporal soft-tissue abnormalities (n = 7 with both modalities) were better appreciated with MR imaging and had low signal intensity on T1- and T2-weighted images. Soft-tissue changes improved but did not disappear completely with treatment.
  
  
  CONCLUSIONS
  CT is preferred at initial diagnosis, as small cortical erosions are better seen. Either modality can be used to follow up soft-tissue evolution. MR imaging may be better for evaluation and follow-up of meningeal enhancement and changes within the osseous medullary cavity.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh, Montefiore University Hospital, PA 15213, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Grandis
authors.forename: H D
authors.initials: HD
authors.lastname: Curtin
authors.forename: V L
authors.initials: VL
authors.lastname: Yu
mesh_terms: D000368:Aged; D004424:Ear Canal / Q000473:pathology; D004431:Ear, External / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009336:Necrosis; D010032:Otitis Externa / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed