Sequence of the superoxide dismutase 1 (SOD 1) gene in familial Parkinson's disease.
Mutations in the superoxide dismutase 1 (SOD1) gene have been detected in affected members of some families with familial amyotrophic lateral sclerosis. To evaluate the possibility of a shared genetic defect in amyotrophic lateral sclerosis and Parkinson's disease, the SOD1 gene was sequenced in index patients with familial Parkinson's disease from 23 families. No changes were detected.
Bandmann
O
O
University Department of Clinical Neurology, (Neurogenetics Section), Institute of Neurology, London, UK.
Davis
M B
MB
Marsden
C D
CD
Harding
A E
AE
D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics; D001483:Base Sequence; D004247:DNA; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D010300:Parkinson Disease / Q000235:genetics*; D013482:Superoxide Dismutase / Q000235:genetics*
D004247:DNA; D013482:Superoxide Dismutase