Fracture blister formation: a laboratory study.
A biomechanical study was performed to examine a proposed mechanism of fracture blister formation. Sixty cadaver ankle skin specimens were subjected to several levels of uniaxial strain and examined histologically. Dermal-epidermal separation patterns similar to those found histologically in previous studies of biopsied fracture blisters were seen in specimens strained 152% and greater. These findings support the hypothesis that fracture blisters can result from strain developed in the skin during initial fracture deformation.
Giordano
C P
CP
Hospital for Joint Diseases, Orthopaedic Institute, New York, New York 10003, USA.
Scott
D
D
Koval
K J
KJ
Kummer
F
F
Atik
T
T
Desai
P
P
D001696:Biomechanical Phenomena; D001768:Blister / Q000209:etiology* / Q000473:pathology; D050723:Fractures, Bone / Q000150:complications*; D006801:Humans; D012867:Skin / Q000473:pathology*