Oral Fusarium infection in a granulocytopenic patient with acute myelogenous leukemia: a case report.
The fungus Fusarium moniliforme causes fusariosis, which can be invasive and fatal in immunocompromised patients. We report a case of oral Fusarium infection in a granulocytopenic patient with acute myelogenous leukemia who developed necrotic ulceration of the gingiva, extending to the alveolar bone, but was otherwise free of any active systemic lesions. Fusarium moniliforme was identified, by histopathology and culture, to be present in the lesion and was deduced to be the causative organism for this invasive oral infection.
Myoken
Y
Y
Department of Dentistry and Oral Surgery, Hiroshima Red Cross-Atomic Bomb Survivors Hospital, Japan.
Sugata
T
T
Kyo
T
T
Fujihara
M
M
D058186:Acute Kidney Injury / Q000209:etiology; D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced* / Q000150:complications; D000666:Amphotericin B / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects; D015251:Epirubicin / Q000009:adverse effects; D005047:Etoposide / Q000008:administration & dosage / Q000009:adverse effects; D017809:Fatal Outcome; D005670:Fusarium; D005882:Gingival Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008297:Male; D008439:Maxillary Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D015122:Mercaptopurine / Q000008:administration & dosage / Q000009:adverse effects; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology*; D009336:Necrosis; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects; D014456:Ulcer; D014751:Vindesine / Q000008:administration & dosage / Q000009:adverse effects
D003561:Cytarabine; D015251:Epirubicin; D005047:Etoposide; D000666:Amphotericin B; D011239:Prednisolone; D015122:Mercaptopurine; D014751:Vindesine