title: Is the transplant-preserving management of renal allograft rupture justified?
abstract: OBJECTIVE
  To evaluate the transplant-preserving management of renal allograft rupture.
  
  
  METHODS
  From April 1982 to January 1994 a total of 238 renal transplantations were performed on 227 patients. Eight cases (3.5%) of renal allograft rupture occurred. Transplant nephrectomy was necessary in one patient. Seven patients were surgically treated with collagen foam, fibrin glue and vicryl mesh.
  
  
  RESULTS
  In all seven cases treated conservatively, renal salvage and satisfactory graft function was achieved. After a mean follow-up of 52.9 months (range 2-94) the mean creatinine level was 15.6 mg/L (range 11-21). Of these seven patients with renal allograft rupture one returned to haemodialysis 22 months after transplantation and had several episodes of rejection. Almost 4.5 years after renal allograft rupture, the creatinine value in six of the seven patients was only slightly higher than the mean creatinine values of all donor kidney recipients (14.4 +/- 5.5 mg/L).
  
  
  CONCLUSIONS
  There should be an attempt to salvage the transplant after allograft rupture in all cases. Using these transplant-preserving techniques, renal function could be achieved for all patients with allograft rupture.
authors.affiliation: Department of Urology, Rheinische Friedrich-Wilhelms University, Medical School, Bonn, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Heimbach
authors.forename: W D
authors.initials: WD
authors.lastname: Miersch
authors.forename: H
authors.initials: H
authors.lastname: Buszello
authors.forename: G
authors.initials: G
authors.lastname: Schoeneich
authors.forename: H U
authors.initials: HU
authors.lastname: Klehr
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003094:Collagen / Q000627:therapeutic use; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D007674:Kidney Diseases / Q000628:therapy*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000628:therapy*; D012422:Rupture, Spontaneous; D013526:Surgical Mesh
chemical_list: D015718:Fibrin Tissue Adhesive; D003094:Collagen