title: Structural, biochemical, and cell biological aspects of the serine proteinase inhibitor SKALP/elafin/ESI.
abstract: Skin-derived antileukoproteinase, also described as elafin or as elastase specific inhibitor, is a serine proteinase inhibitor which is thought to play a regulatory role in inflammation. Research in the last few years has increased our knowledge on the structural, biochemical, and cell biological aspects of this molecule. Here we will review the most relevant literature presently available on this proteinase inhibitor.
authors.affiliation: Department of Dermatology, University Hospital, Nijmegen, The Netherlands.
authors.forename: H O
authors.initials: HO
authors.lastname: Molhuizen
authors.forename: J
authors.initials: J
authors.lastname: Schalkwijk
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D053491:Proteinase Inhibitory Proteins, Secretory; D011506:Proteins; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000502:physiology
chemical_list: D053491:Proteinase Inhibitory Proteins, Secretory; D011506:Proteins; D015842:Serine Proteinase Inhibitors