Hepatobiliary pruritus: what are effective treatments?
Pruritus is a common symptom in patients with hepatobiliary disease. Numerous treatments have been attempted. We review published therapeutic trials for hepatobiliary pruritus and utilize statistical analysis to evaluate treatment results. Randomized placebo-controlled studies show cholestyramine, rifampin, naloxone, S-adenosylmethionine, prednisolone, and propofol to be effective. Suggestions for future studies of the treatment of hepatobiliary puruitus are proposed.
Connolly
C S
CS
Division of Dermatology, Philadelphia College of Osteopathic Medicine, PA, USA.
Kantor
G R
GR
Menduke
H
H
D001660:Biliary Tract Diseases / Q000150:complications*; D002986:Clinical Trials as Topic; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology*