title: [Immunocyte subpopulations in histologic sections of breast tumors].
abstract: A study of tumor infiltrating lymphocytes was carried out on cryostat sections of breast tumors in 27 patients using 24 monoclonal antibodies. Two types of infiltration--stromal and intraparenchymal--were identified. Certain correlations characteristic of subpopulation levels of immunocompetent cells identifiable by monoclonal antibody clusters CD8, CD22, CD38 and CD7; CD74 and CD4; CD11b and CD22, CD37 were established. The study also established a correlation between levels of immunocompetent cells infiltration (CD4+, CD7+, CD8+ and CD11b+) and tumor size and regional lymph node involvement.
authors.forename: N N
authors.initials: NN
authors.lastname: Tupitsyn
authors.forename: E V
authors.initials: EV
authors.lastname: Artamonova
authors.forename: Z G
authors.initials: ZG
authors.lastname: Kadagidze
authors.forename: N G
authors.initials: NG
authors.lastname: Blokhina
authors.forename: A I
authors.initials: AI
authors.lastname: Baryshnikov
authors.forename: H
authors.initials: H
authors.lastname: Moldenhauer
authors.forename: L
authors.initials: L
authors.lastname: Boumcelle
mesh_terms: D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis; D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008207:Lymphatic Metastasis; D016131:Lymphocyte Subsets
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000951:Antigens, Neoplasm