Intra-arterial infusion chemotherapy in combination with a biscoclaurine alkaloid, Cepharanthin, to treat bone metastasis arising from renal cell carcinoma.
A 64-year-old man with iliac bone metastasis from left renal cell carcinoma was treated by intra-arterial infusion chemotherapy using vinblastine and epirubicine in combination with a biscoclaurine alkaloid, Cepharanthin. A good response was confirmed by computed tomography scan and the symptoms related to the metastatic lesion were much improved. Partial resection of the left iliac bone was performed when no viable cancer cells were found in the metastatic lesion.
Shichiri
Y
Y
Department of Urology, Faculty of Medicine, Kyoto University, Japan.
Kanba
T
T
Yoshida
S
S
Arai
Y
Y
Kakehi
Y
Y
Yoshida
O
O
D000470:Alkaloids / Q000627:therapeutic use*; D000792:Angiography; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D044182:Benzylisoquinolines; D001706:Biopsy; D001859:Bone Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D015251:Epirubicin / Q000627:therapeutic use; D006801:Humans; D007085:Ilium / Q000000981:diagnostic imaging; D007269:Injections, Intra-Arterial; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000627:therapeutic use; D052117:Benzodioxoles
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D044182:Benzylisoquinolines; D015251:Epirubicin; D014747:Vinblastine; C006947:cepharanthine; D052117:Benzodioxoles