[Complete anorectal stenosis due to paracetamol and salicylamide suppositories].
A female patient previously diagnosed of psychiatric disease used a compound of paracetamol-salicilamide-codeine in suppositories, daily, for more than one year, for migraine. She developed a complete recto-anal stenosis and bowel obstruction requiring permanent colostomy. Ulceration and recto-anal stenosis have been described in association with the use of suppositories, mainly ergotamine. However, this is the first case of total recto-anal stenosis.
Mata
A
A
Departamento de Cirugía, Hospital La Paz, Madrid.
Galindo
A
A
Díaz
J
J
Marijuan
J L
JL
Aguilera
M J
MJ
D000082:Acetaminophen / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001004:Anus Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D003061:Codeine / Q000008:administration & dosage; D003125:Colostomy; D003251:Constriction, Pathologic / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery; D004338:Drug Combinations; D005260:Female; D006801:Humans; D001523:Mental Disorders / Q000150:complications; D012002:Rectal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D012457:Salicylamides / Q000008:administration & dosage / Q000009:adverse effects*; D013488:Suppositories
D004338:Drug Combinations; D012457:Salicylamides; D013488:Suppositories; D000082:Acetaminophen; C031060:salicylamide; D003061:Codeine