title: Structure and function of DNA-binding proteins.
abstract: The past year has seen the determination of over three dozen new structures of DNA-binding proteins. Highlights of new structural motifs include the DNA-binding domain of p53 tumor suppressor and the amino-terminal fragment of Escherichia coli DNA topoisomerase I. Other structures illustrate variations of known structural motifs, including co-crystals of helix-turn-helix, basic helix-loop-helix, and zinc finger proteins.
authors.affiliation: University of California, Department of Molecular and Cell Biology, Berkeley 94720-3206, USA.
authors.forename: H C
authors.initials: HC
authors.lastname: Nelson
mesh_terms: D004268:DNA-Binding Proteins / Q000737:chemistry* / Q000502:physiology*; D013329:Structure-Activity Relationship
chemical_list: D004268:DNA-Binding Proteins