[Rapid progression to AIDS in a patient with infection from a strain of syncytium forming HIV-1].
A woman who had recently become infected with HIV-1 after sexual relations with a seropositive subject presented a rapid fall in CD4+ T lymphocytes and evolved to AIDS 13 months after primoinfection. The most plausible cause for the rapid disease progression in this patient was the observation of a viral syncytium forming phenotype. The plasmatic viremia was high throughout the follow up despite the administration of antiretroviral drugs.
Soriano
V
V
Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid.
Heredia
A
A
Bravo
R
R
Gutiérrez
M
M
González-Lahoz
J
J
D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology*; D000328:Adult; D018791:CD4 Lymphocyte Count; D005260:Female; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans