title: Urinary excretion of cortisol after immunisation.
abstract: Urinary cortisol excretion and rectal temperature were measured in 66 infants before and after immunisation against diphtheria, tetanus, pertussis, and Haemophilus influenzae type b. Immunisation produced a significant increase of rectal temperature the next night at all ages. Infants without an adult-like night time body temperature pattern had a significant increase in urinary cortisol excretion night and morning after immunisation. Once an adult-like night time body temperature pattern developed immunisation no longer significantly raised urinary cortisol output.
authors.affiliation: Department of Child Health, University of Leicester.
authors.forename: J
authors.initials: J
authors.lastname: Westaway
authors.forename: C M
authors.initials: CM
authors.lastname: Atkinson
authors.forename: T
authors.initials: T
authors.lastname: Davies
authors.forename: S A
authors.initials: SA
authors.lastname: Petersen
authors.forename: M P
authors.initials: MP
authors.lastname: Wailoo
mesh_terms: D000367:Age Factors; D001833:Body Temperature Regulation / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000494:pharmacology*; D005260:Female; D018073:Haemophilus Vaccines / Q000494:pharmacology*; D006801:Humans; D006854:Hydrocortisone / Q000652:urine*; D007114:Immunization; D007223:Infant; D008297:Male; D012007:Rectum / Q000502:physiology; D018074:Vaccines, Conjugate / Q000494:pharmacology
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D018073:Haemophilus Vaccines; D018074:Vaccines, Conjugate; C080881:diphtheria-tetanus-pertussis-haemophilus b conjugate vaccine; D006854:Hydrocortisone