Assessment of in-line filters to prolong the life of intravenous cannulae in cystic fibrosis patients.
Twelve patients with cystic fibrosis received 12 courses of intravenous antibiotics, each over 10-14 days, both with and without the use of an extended-life disposable filter. The design of the trial was to replace the Venflon cannulae as they became non-patent and inserting a filter on alternate occasions. Thus each patient acted as her/his own control. Comparison of times during which cannulae remained patent showed a 50% improvement with use of a filter for 4 patients and no change for 7 patients. There was no significant difference associated with the use of a filter for the group as a whole but our small sample size excludes modest improvements.
Richards
C
C
Department of Pharmacy, University Hospital of Wales, Cardiff, UK.
Millar-Jones
L
L
Alfaham
M
M
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002406:Catheterization, Peripheral / Q000379:methods*; D002648:Child; D018592:Cross-Over Studies; D003550:Cystic Fibrosis / Q000188:drug therapy*; D005260:Female; D005374:Filtration / Q000295:instrumentation*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male
D000900:Anti-Bacterial Agents