title: [Otomycosis and topical application of thimerosal: study of 152 cases].
abstract: OBJECTIVE
  To evaluate the effectiveness of the topical application of Timerosal (merthilate tintura) in mycosis involving the external auditory canal.
  
  
  METHODS
  The study includes 152 patients with the clinical, otoscopic and microscopic diagnosis of otomycosis. Results were assessed 72 hours and 10 days after the application.
  
  
  RESULTS
  Bacteriological study was performed in 83 patients, finding Aspergilly niger in 54.0% of the cases, Candida albicans in 25.4%, Aspergillus fumigatus in 15.8% and Penicillium in 4.8%. Improvement at 72 h. was found in 66.4% and at 10 days in 93.4% of the patients. Bacteriological contamination was found in 6.6% of the total.
  
  
  CONCLUSIONS
  In most of the patients, the otomycosis healed after cleaning of the external auditory canal and topical application of timerosal. This method is easy to apply, fast, effective, of low cost and few side effects.
authors.affiliation: Hospital Clínico Universitario, Zaragoza.
authors.forename: J
authors.initials: J
authors.lastname: Tisner
authors.forename: J
authors.initials: J
authors.lastname: Millán
authors.forename: P
authors.initials: P
authors.lastname: Rivas
authors.forename: I
authors.initials: I
authors.lastname: Adiego
authors.forename: A
authors.initials: A
authors.lastname: Castellote
authors.forename: H
authors.initials: H
authors.lastname: Valles
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D001234:Aspergillus niger / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification*; D002648:Child; D004431:Ear, External / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D010407:Penicillium / Q000302:isolation & purification*; D011446:Prospective Studies; D013849:Thimerosal / Q000008:administration & dosage* / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D013849:Thimerosal