Diarrhea-associated hemolytic-uremic syndrome in a child with nail-patella syndrome.
A 5-year-old girl with nail-patella syndrome had diarrhea-associated hemolytic-uremic syndrome. Nail-patella syndrome is associated with a glomerulopathy characterized by the presence of fibrillar collagen within the glomerular basement membrane. Hemolytic-uremic syndrome has also been reported in patients with collagen type III glomerulopathy, a disorder also characterized by the presence of fibrillar collagen within the basement membrane. Patients with nail-patella syndrome or with collagen type III glomerulopathy may be predisposed to hemolytic-uremic syndrome.
Robson
W L
WL
Department of Pediatric Nephrology, Children's Hospital, Greenville Hospital System, SC 29605-4253, USA.
Leung
A K
AK
D001485:Basement Membrane / Q000378:metabolism; D002675:Child, Preschool; D003094:Collagen / Q000378:metabolism; D003967:Diarrhea / Q000209:etiology*; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology*; D006801:Humans; D007678:Kidney Glomerulus / Q000378:metabolism; D009261:Nail-Patella Syndrome / Q000150:complications* / Q000235:genetics / Q000378:metabolism
D003094:Collagen