title: Changes in taste associated with intravenous administration of pentamidine (revised)
abstract: In this pilot study the authors set out to: (a) describe the incidence of taste changes associated with intravenous (i.v.) pentamidine treatment; and (b) determine the factors that are related to making the taste changes better and worse. A convenience sample (N = 18) of adult male outpatients with AIDS participated in this study. One hundred percent of the participants experienced an unpleasant taste after the administration of pentamidine. The largest percentage of patients had a metallic taste (89%, n = 16); while 67% (n = 12) experienced a bitter taste. These data suggest that healthcare providers need to assess for the unpleasant taste associated with i.v. pentamidine and develop appropriate management strategies.
authors.affiliation: Infusion Center, Kaiser Permanente Medical Group, San Francisco, CA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Glover
authors.forename: S
authors.initials: S
authors.lastname: Dibble
authors.forename: C
authors.initials: C
authors.lastname: Miaskowski
authors.forename: R
authors.initials: R
authors.lastname: Geibert
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000451:nursing; D000328:Adult; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009730:Nursing Assessment; D010419:Pentamidine / Q000009:adverse effects*; D010865:Pilot Projects; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000451:nursing; D013649:Taste / Q000187:drug effects*
chemical_list: D010419:Pentamidine