title: [A case of sarcoidosis with right pneumothorax and multiple cavities in both lung fields].
abstract: A 26-year-old man was admitted to our hospital for evaluation of cavitary lesions on his chest X-ray film. Chest CT and conventional tomograms showed multiple cavities in both lung fields, as well as hilar and mediastinal lymphadenopathy. He had uveitis and the laboratory data showed a high level of angiotensin converting enzyme in the serum. Histological findings of the specimen obtained by transbronchial lung biopsy showed non-caseating epithelioid cell granuloma, consistent with sarcoidosis. Corticosteroid therapy (prednisolone 40 mg/day) resulted in reduction of the cavitary lesions and the lymphadenopathy. Negative bacteriological studies and the clinical course strongly suggested primary cavitation, a relatively rare form of pulmonary parenchymal involvement in sarcoidosis.
authors.affiliation: Department of Medicine and Physical Therapy, University of Tokyo School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: K
authors.initials: K
authors.lastname: Ohta
authors.forename: H
authors.initials: H
authors.lastname: Takizawa
authors.forename: N
authors.initials: N
authors.lastname: Kobayashi
authors.forename: A
authors.initials: A
authors.lastname: Ishii
authors.forename: H
authors.initials: H
authors.lastname: Sugiyama
authors.forename: M
authors.initials: M
authors.lastname: Dohi
authors.forename: M
authors.initials: M
authors.lastname: Suko
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
mesh_terms: D000328:Adult; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D011030:Pneumothorax / Q000150:complications*; D011239:Prednisolone / Q000008:administration & dosage; D011859:Radiography; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000000981:diagnostic imaging*
chemical_list: D011239:Prednisolone