title: Early jugular bulb oxygenation monitoring in comatose patients after an out-of-hospital cardiac arrest.
abstract: OBJECTIVE
  To determine the role of early jugular bulb oxygenation monitoring in comatose patients after cardiac arrest.
  
  
  METHODS
  Prospective sequential study.
  
  
  METHODS
  Medical intensive care unit in a university hospital.
  
  
  METHODS
  Thirteen patients comatose after out-of-hospital cardiac arrest.
  
  
  METHODS
  A standard hemodynamic protocol.
  
  
  RESULTS
  Jugular bulb oxygen saturation levels and oxygen extraction ratios could not discriminate between patients with good (6) and poor (7) cerebral outcome. This was also true for the jugular bulb-arterial lactate difference. Survivors had significantly higher overall oxygen transport values than non-survivors.
  
  
  CONCLUSIONS
  Jugular bulb oxygenation monitoring during the first few hours after cardiac arrest cannot reliably discriminate between comatose patients with a good and poor cerebral outcome. Further studies with an extended monitoring period are thus required.
authors.affiliation: Department of General Internal Medicine, University Hospital Leiden, The Netherlands.
authors.forename: J G
authors.initials: JG
authors.lastname: van der Hoeven
authors.forename: J
authors.initials: J
authors.lastname: de Koning
authors.forename: E A
authors.initials: EA
authors.lastname: Compier
authors.forename: A E
authors.initials: AE
authors.lastname: Meinders
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001784:Blood Gas Analysis; D003128:Coma / Q000097:blood* / Q000209:etiology / Q000401:mortality; D004632:Emergency Medical Services; D005260:Female; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D007601:Jugular Veins; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000097:blood*; D010101:Oxygen Consumption; D011379:Prognosis; D011446:Prospective Studies; D016019:Survival Analysis
chemical_list: D010100:Oxygen