Pregnancies after testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia.
In this study (May 1 until August 31, 1994) a total of 15 azoospermic patients suffering from testicular failure were treated with a combination of testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI). Spermatozoa were available for ICSI in 13 of the patients. Out of 182 metaphase II injected oocytes, two-pronuclear fertilization was observed in 87 (47.80%); 57 embryos (65.51%) were obtained for either transfer or cryopreservation. Three ongoing pregnancies out of 12 replacements (25%) were established, including one singleton, one twin and one triplet gestation. The ongoing implantation rate was 18% (six fetal hearts out of 32 embryos replaced).
Devroey
P
P
Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free University, Belgium.
Liu
J
J
Nagy
Z
Z
Goossens
A
A
Tournaye
H
H
Camus
M
M
Van Steirteghem
A
A
Silber
S
S
D000328:Adult; D002469:Cell Separation; D003593:Cytoplasm; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008845:Microinjections; D009845:Oligospermia / Q000473:pathology*; D009865:Oocytes; D011247:Pregnancy; D018873:Pregnancy Rate; D013084:Sperm-Ovum Interactions; D013737:Testis / Q000166:cytology*