title: The use of recombinant factor VIIa in a patient with acquired haemophilia A undergoing surgery.
abstract: An elderly woman with acquired haemophilia A secondary to a monoclonal gammopathy, required elective surgery for a parotid tumour but was unable to tolerate conventional treatment. Recombinant activated factor VII (rVIIa) was used successfully to cover a biopsy and then subsequent resection of the tumour. The use of rVIIa in the management of acquired inhibitors is discussed.
authors.affiliation: Haemophilia Centre, St Thomas' Hospital, London, UK.
authors.forename: H A
authors.initials: HA
authors.lastname: Doughty
authors.forename: A
authors.initials: A
authors.lastname: Northeast
authors.forename: L
authors.initials: L
authors.lastname: Sklair
authors.forename: T
authors.initials: T
authors.lastname: Roques
authors.forename: A E
authors.initials: AE
authors.lastname: Young
authors.forename: G F
authors.initials: GF
authors.lastname: Savidge
authors.forename: B J
authors.initials: BJ
authors.lastname: Hunt
mesh_terms: D000368:Aged; D017558:Elective Surgical Procedures; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006467:Hemophilia A / Q000188:drug therapy* / Q000209:etiology; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; D015942:Factor VIIa