[Microbiological and clinical study of fungemia between 1981 and 1992].
Fungi were isolated from 113 (14.2%) of 789 patients with positive blood cultures at Oita Medical University Hospital between 1981 and 1992. The rates of fungemia increased in recent years, 13.9% (1981-1985), 12.1% (1986-1988) and 16.9% (1989-1992). The isolated fungi were Candida parapsilosis (25.7%), C. albicans (24.8%), C. tropicalis (14.2%), Trichosporon beigelii (10.6%), C. glabrata (8.0%) and so on. The major fungi were T. beigelii and C. glabrata in patients with hematologic malignancies, whereas they were C. albicans and C. parapsilosis in patients with non-hematologic diseases and C. glabrata increased in both groups. Prophylactic or emiric administration of antifungal agents probably influenced the difference of the causative organisms in the two groups.
Yamakami
Y
Y
Second Department of Internal Medicine, Oita Medical University.
Tashiro
T
T
Tokimatsu
I
I
Nagai
H
H
Nagaoka
H
H
Hashimoto
A
A
Goto
Y
Y
Nasu
M
M
Yamasaki
T
T
Ito
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000382:microbiology*; D014250:Trichosporon / Q000302:isolation & purification
D000935:Antifungal Agents