Spinal gliosarcoma: a light, immunohistochemical and ultrastructural study.
Gliosarcomas are mixed tumors of the brain containing both malignant neuroectodermal and mesenchymal components. Over 100 cases have been reported within the brain; however, to our knowledge, this is the first reported case located primarily within the spinal cord. Along with a review of the literature, the light, immunohistochemical and ultrastructural findings of a spinal gliosarcoma are reported in a 41-year-old woman with a previously diagnosed oligodendroglioma of the cerebellum 15 years earlier and a concurrent pituitary adenoma. The spinal tumor appears to be morphologically identical to its intracranial counterpart.
Carstens
P H
PH
Department of Pathology, University of Louisville School of Medicine, KY 40292, USA.
Johnson
G S
GS
Jelsma
L F
LF
D000328:Adult; D002467:Cell Nucleus / Q000473:pathology*; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D018316:Gliosarcoma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000032:analysis; D013120:Spinal Cord Neoplasms / Q000737:chemistry / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins; D014746:Vimentin