title: Achieving and maintaining compliance with the ketogenic diet.
abstract: The ketogenic diet, a treatment for intractable epilepsy, is rarely initiated because it requires strict compliance with a diet that is perceived to be unpalatable. In a case study of a 15-year-old girl with uncontrolled epilepsy, we used a stimulus-choice procedure to assess relative preferences of 33 foods from the diet and to develop two treatments based on Premack's principle. The results of a multielement analysis showed that both treatments increased dietary compliance. Compliance was maintained with generalization of treatment across settings, and was associated with a 40% reduction in seizures.
authors.affiliation: Kennedy Krieger Institute, Baltimore, Maryland 21205, USA.
authors.forename: A
authors.initials: A
authors.lastname: Amari
authors.forename: N C
authors.initials: NC
authors.lastname: Grace
authors.forename: W W
authors.initials: WW
authors.lastname: Fisher
mesh_terms: D000293:Adolescent; D001521:Behavior Therapy / Q000379:methods*; D004827:Epilepsy / Q000178:diet therapy* / Q000523:psychology; D005260:Female; D005518:Food Preferences / Q000523:psychology*; D006801:Humans; D008607:Intellectual Disability / Q000178:diet therapy* / Q000523:psychology; D007657:Ketone Bodies / Q000096:biosynthesis*; D010349:Patient Compliance / Q000523:psychology
chemical_list: D007657:Ketone Bodies