title: Evaluation of an automated urine chemistry reagent-strip analyzer.
abstract: We evaluated the Miles Inc., Clinitek Atlas Automated Urine Chemistry Analyzer for 11 tests: bilirubin, color, glucose, ketones, leukocyte esterase, nitrite, occult blood, pH, protein, specific gravity, and urobilinogen. The instrument uses a roll of reagent strips affixed to a clear plastic support; urine specimens are automatically pipetted onto these strips. The instrument measures the pads' color using reflectance colorimetry. Specific gravity is measured using a fiberoptic refractive index method. Four hospitals participated in the evaluation, and tests were performed only on fresh urine samples. We found the instrument easy to use; it has walk-away capability with up to 40-specimen loading capacity plus spaces for STATs, calibrators and controls. We found good comparability with chemical tests and other nonreagent strip procedures, as well as good agreement with the Miles Inc. Clinitek 200+ urine chemistry analyzer and visual reading of the Miles Inc. Multistix Reagent Strips. The Clinitek Atlas is rugged and reliable, and is suitable for a high-volume urinalysis laboratory.
authors.affiliation: Department of Pathology, Ohio State University, Columbus 43210-1240, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Lott
authors.forename: W R
authors.initials: WR
authors.lastname: Johnson
authors.forename: K E
authors.initials: KE
authors.lastname: Luke
mesh_terms: D001331:Automation / Q000592:standards; D001663:Bilirubin / Q000652:urine; D002265:Carboxylic Ester Hydrolases / Q000652:urine; D006029:Glycosuria; D006417:Hematuria; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007659:Ketones / Q000652:urine; D007962:Leukocytes / Q000201:enzymology; D009573:Nitrites / Q000652:urine; D009780:Occult Blood; D011507:Proteinuria; D011934:Reagent Strips / Q000592:standards*; D013046:Specific Gravity; D016482:Urinalysis / Q000379:methods*
chemical_list: D007659:Ketones; D009573:Nitrites; D011934:Reagent Strips; C021443:leukocyte esterase; D002265:Carboxylic Ester Hydrolases; D001663:Bilirubin