title: Functional hyposplenism due to a primary epithelioid hemangioendothelioma of the spleen.
abstract: We present a unique case of functional hyposplenism due to massive involvement of the spleen by a rare tumor, an epithelioid hemangioendothelioma, in a 9-year-old girl. To our knowledge, three previous cases of this disorder involving the spleen have been reported, but this is the first associated with functional hyposplenism.
authors.affiliation: Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
authors.forename: H L
authors.initials: HL
authors.lastname: Budke
authors.forename: P P
authors.initials: PP
authors.lastname: Breitfeld
authors.forename: R S
authors.initials: RS
authors.lastname: Neiman
mesh_terms: D002648:Child; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D013154:Spleen / Q000473:pathology / Q000503:physiopathology*; D013160:Splenic Neoplasms / Q000473:pathology / Q000503:physiopathology*