Evaluation of impedance cardiography: comparison of NCCOM3-R7 with Fick and thermodilution methods.
OBJECTIVE
To assess the degree of error of the BoMed NCCOM3 model revision seven (R7) impedance cardiograph in determining stroke volume and estimated cardiac output.


METHODS
Three-group, within-subject, repeated measures design.


METHODS
Group 1: patients (n = 17) with heart disease undergoing an elective coronary angiogram; group 2: patients (n = 28) after elective heart surgery; and group 3: healthy volunteers (n = 28).


METHODS
Cardiac output was determined by the BoMed NCCOM3-R7 impedance cardiograph, Fick principle, and thermodilution method. The NCCOM3-R7 was compared with the direct Fick and thermodilution methods in groups 1 and 2, respectively, to estimate validity coefficients. In group 3, repeated measures were obtained with the NCCOM3-R7 to calculate reliability coefficients.


RESULTS
The NCCOM3-R7 underestimated Fick measurements by 1.050 +/- 1.529 L/min at rest and 1.505 +/- 2.214 L/min during exercise. Correlation coefficients of 0.684 at rest (p = 0.001) and 0.219 during exercise (p = 0.248) were obtained. The NCCOM3-R7 underestimated thermodilution values by 0.425 +/- 1.325 L/min in subjects initially after heart surgery and 0.358 +/- 1.235 L/min 2 to 4 hours later. Correlation coefficients of 0.547 (p = 0.002) and 0.505 (p = 0.004) were obtained for the two time periods, respectively. A reliability coefficient of 0.837 was calculated with healthy subjects.


CONCLUSIONS
The NCCOM3-R7 has a clinically unacceptable level of error for evaluating cardiac performance in patients with heart disease.
Yakimets
J
J
Critical Care Nursing Program, Misericordia Hospital, Edmonton, Alberta, Canada.
Jensen
L
L
D000328:Adult; D000368:Aged; D002302:Cardiac Output; D006348:Cardiac Surgical Procedures; D002307:Cardiography, Impedance / Q000379:methods*; D003951:Diagnostic Errors; D015444:Exercise; D005260:Female; D006331:Heart Diseases / Q000503:physiopathology; D006801:Humans; D007201:Indicator Dilution Techniques; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D015203:Reproducibility of Results; D012146:Rest; D013815:Thermodilution