title: Absorption of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans by breast-fed infants.
abstract: The absorption of polychlorinated biphenyls, dibenzo-p-dioxins and dibenzofurans was studied in four breast-fed infants. The absorption was measured by comparing the estimated total intake and the excretion in faeces, during 48 hours, at three different time points; 1, 2 and 3 months post parta. The levels of the analysed compounds in the human milk are typical for Sweden, i.e approximately 20 ppt toxic equivalents for the dibenzo-p-dioxins and dibenzofurans and for the polychlorinated biphenyls approximately 16 ppt toxic equivalents. For most of the congeners the absorption is found to be over 95%. Higher excretion is noticed for heptachlorinated and octachlorinated dioxins.
authors.affiliation: Institute of Environmental Chemistry, University of Umeå, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Dahl
authors.forename: G
authors.initials: G
authors.lastname: Lindström
authors.forename: K
authors.initials: K
authors.lastname: Wiberg
authors.forename: C
authors.initials: C
authors.lastname: Rappe
mesh_terms: D000042:Absorption; D001572:Benzofurans / Q000378:metabolism*; D001822:Body Burden; D001942:Breast Feeding; D005243:Feces / Q000737:chemistry*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007231:Infant, Newborn; D008895:Milk, Human / Q000737:chemistry*; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000378:metabolism; D018570:Risk Assessment
chemical_list: D001572:Benzofurans; D000072317:Polychlorinated Dibenzodioxins; C023614:dibenzofuran; D011078:Polychlorinated Biphenyls