title: Pregnancy with spermatozoa from a globozoospermic man after intracytoplasmic sperm injection treatment.
abstract: We present a case of third trimester pregnancy occurring in a 29 year old woman after intracytoplasmic sperm injection (ICSI) treatment with spermatozoa from a globozoospermic man. We believe this is the first reported case. A 37 year old man was diagnosed with globozoospermia with normal sperm count and motility. In-vitro fertilization and subzonal insemination treatments failed to achieve fertilization of any eggs. The ICSI method produced 50% fertilization, 75% cleavage rate and a singleton pregnancy with a female fetus. No pregnancy or fetal abnormalities have been noted after > 7 months of gestation.
authors.affiliation: Pedieos IVF Center, Nicosia, Cyprus.
authors.forename: K M
authors.initials: KM
authors.lastname: Trokoudes
authors.forename: N
authors.initials: N
authors.lastname: Danos
authors.forename: L
authors.initials: L
authors.lastname: Kalogirou
authors.forename: R
authors.initials: R
authors.lastname: Vlachou
authors.forename: T
authors.initials: T
authors.lastname: Lysiotis
authors.forename: N
authors.initials: N
authors.lastname: Georghiades
authors.forename: S
authors.initials: S
authors.lastname: Lerios
authors.forename: K
authors.initials: K
authors.lastname: Kyriacou
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D008845:Microinjections; D008854:Microscopy, Electron; D010063:Ovum; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D013077:Sperm Head / Q000473:pathology; D013094:Spermatozoa / Q000473:pathology* / Q000648:ultrastructure