title: [Resorption coefficients and prevention of Pu-239 oxide entry through microtrauma of the skin].
abstract: The resorption coefficients of 239Pu were from (3.0 +/- 0.3) x 10(-4) to (6.3 +/- 1.4) x 10(-4) after contamination of skin microwounds of rats with plutonium oxides. Effective periods of the radionuclide accumulation in the organism were from 0.18 to 0.48 days. Disactivation of microinjuries with 3% hydrogen peroxide solution followed by electrocoagulation of the involved skin sites helped reduce the level of 239Pu in the tested skin site by 12.5 times, and by 4.5 to 7.5 times in the skeleton and liver. These measures, in combination with a 64-day course of pentacin and zincacin injections, helped reduce the level of the radionuclide in the organism 12-fold.
authors.forename: A G
authors.initials: AG
authors.lastname: Bazhin
mesh_terms: D000818:Animals; D004564:Electrocoagulation; D006861:Hydrogen Peroxide / Q000627:therapeutic use; D008297:Male; D010087:Oxides / Q000378:metabolism*; D004369:Pentetic Acid / Q000008:administration & dosage; D011005:Plutonium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000293:injuries*; D013997:Time Factors; D014947:Wounds and Injuries / Q000188:drug therapy / Q000378:metabolism* / Q000601:surgery
chemical_list: D010087:Oxides; D011005:Plutonium; D004369:Pentetic Acid; D006861:Hydrogen Peroxide
vernacular_title: Koéffitsienty rezorbtsii i preduprezhdenie postupleniia oksidov 239Pu v organizm iz zagriaznennykh mikrotravm kozhi.