title: Randomized comparison of polyglycolic acid and polyglyconate sutures for abdominal fascial closure after laparotomy in patients with suspected impaired wound healing.
abstract: A randomized study of abdominal fascial closure using interrupted polyglyconate and polyglycolic acid sutures after laparotomy was carried out in 204 consecutive patients with suspected impaired wound healing. There were no statistically significant differences between the two sutures with regard to the development of fascial disruption and incisional hernia. Wound infection demanding surgical intervention was found in 7 per cent of patients with polyglyconate sutures and in 16 per cent of those with polyglycolic acid sutures (P = 0.04). Monofilament polyglyconate suture does not reduce the incidence of fascial disruption and incisional hernia after laparotomy in patients with suspected impaired wound healing but the incidence of wound infection may be reduced compared with that of multifilament polyglycolic acid suture.
authors.affiliation: Department of Surgical Gastroenterology, Odense University Hospital, Denmark.
authors.forename: P J
authors.initials: PJ
authors.lastname: Osther
authors.forename: P
authors.initials: P
authors.lastname: Gjøde
authors.forename: B B
authors.initials: BB
authors.lastname: Mortensen
authors.forename: P B
authors.initials: PB
authors.lastname: Mortensen
authors.forename: J
authors.initials: J
authors.lastname: Bartholin
authors.forename: F
authors.initials: F
authors.lastname: Gottrup
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery; D000368:Aged; D005260:Female; D006555:Hernia, Ventral / Q000209:etiology; D006801:Humans; D007813:Laparotomy; D008297:Male; D011100:Polyglycolic Acid; D011108:Polymers; D012086:Reoperation; D013530:Surgical Wound Infection / Q000209:etiology; D013537:Sutures; D014945:Wound Healing
chemical_list: D011108:Polymers; D011100:Polyglycolic Acid; C046409:polyglyconate