title: Rare primary signet ring carcinoma of the pancreas.
abstract: Signet ring carcinoma of the pancreas is a rare mucin-producing variant occurring in less than 1% of pancreatic carcinoma. The fourth leading cause of cancer deaths in the U.S., pancreatic carcinoma is increasing in incidence and mortality. It is difficult to detect during the early stages of the disease and usually become apparent when extrahepatic biliary obstruction occurs. Early radiologic findings may be negative and there is no well defined tumor marker for this neoplasm.
authors.affiliation: Department of Pathology, Truman Medical Center, Kansas City, Missouri 64108, USA.
authors.forename: C P
authors.initials: CP
authors.lastname: McArthur
authors.forename: R
authors.initials: R
authors.lastname: Fiorella
authors.forename: B M
authors.initials: BM
authors.lastname: Saran
mesh_terms: D000368:Aged; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D052776:Female Urogenital Diseases / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D009543:Nifedipine / Q000627:therapeutic use; D010179:Pancreas / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006435:Renal Dialysis; D013203:Staphylococcal Infections / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D009543:Nifedipine