title: Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance.
abstract: Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.
authors.affiliation: Max-Delbrück Laboratory, Köln, Germany.
authors.forename: M R
authors.initials: MR
authors.lastname: Grant
authors.forename: L
authors.initials: L
authors.lastname: Godiard
authors.forename: E
authors.initials: E
authors.lastname: Straube
authors.forename: T
authors.initials: T
authors.lastname: Ashfield
authors.forename: J
authors.initials: J
authors.lastname: Lewald
authors.forename: A
authors.initials: A
authors.lastname: Sattler
authors.forename: R W
authors.initials: RW
authors.lastname: Innes
authors.forename: J L
authors.initials: JL
authors.lastname: Dangl
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics* / Q000382:microbiology; D029681:Arabidopsis Proteins; D001483:Base Sequence; D005798:Genes, Bacterial; D017343:Genes, Plant; D005816:Genetic Complementation Test; D008969:Molecular Sequence Data; D009154:Mutation; D016366:Open Reading Frames; D010935:Plant Diseases / Q000235:genetics*; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D030821:Plants, Genetically Modified; D012150:Polymorphism, Restriction Fragment Length; D011549:Pseudomonas / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D014170:Transformation, Genetic; D014774:Virulence / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; D010940:Plant Proteins; C095014:RPM1 protein, Arabidopsis