title: Neoplasms in Proteus syndrome.
abstract: We report on 2 children with Proteus syndrome who developed neoplasms. Patient 1 had a probable mesothelioma, although papillary carcinoma of the thyroid could not be completely ruled out. Patient 2 had bilateral ovarian serous cystadenomas with nuclear atypia. Other unusual neoplasms in Proteus syndrome are discussed, together with their etiologic and pathogenetic possibilities.
authors.affiliation: Division of Genetics, University of Tennessee, Memphis, USA.
authors.forename: P L
authors.initials: PL
authors.lastname: Gordon
authors.forename: R S
authors.initials: RS
authors.lastname: Wilroy
authors.forename: O E
authors.initials: OE
authors.lastname: Lasater
authors.forename: M M
authors.initials: MM
authors.lastname: Cohen
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D018293:Cystadenoma, Serous / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008654:Mesothelioma / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology; D016715:Proteus Syndrome / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology