Botulinum toxin for suspected pseudoachalasia.
We describe a 74-yr-old man with stage III adenocarcinoma of the lung who presented with suspected malignancy-induced secondary achalasia and responded clinically to intrasphincteric injections of botulinum toxin type A (Botox, Allergen Inc., Irvine, CA). We discuss the use of botulinum toxin in this setting, as well as diagnostic strategies to differentiate achalasia from pseudoachalasia.
Vallera
R A
RA
Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Brazer
S R
SR
D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary; D000368:Aged; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D004931:Esophageal Achalasia / Q000209:etiology / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000150:complications / Q000556:secondary; D004943:Esophagogastric Junction / Q000503:physiopathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008365:Manometry
D001905:Botulinum Toxins