[Effects of stellate ganglion block on coronary circulation during acute coronary occlusion].
To evaluate effects of stellate ganglion block (SGB) on coronary circulation under coronary occlusion, the changes in cardiac function and tissue blood flow in the myocardial ischemic area after right and left SGB were observed in the dogs. Tissue blood flow in the myocardial ischemic area measured with laser doppler flowmeter showed no significant change after right or left SGB. In the right SGB group, heart rate, circumflex branch blood flow and rate pressure product decreased significantly (P < 0.01); end-diastolic pressure increased slightly (P < 0.05); myocardial oxygen extraction rate showed no significant change. On the other hand, in the left SGB group, heart rate, circumflex branch blood flow and rate pressure product showed no significant changes, while end-diastolic pressure and myocardial oxygen extraction rate increased significantly (P < 0.05). These data suggest that although right SGB might be useful to improve the oxygen demand-supply relation, left SGB does not improve the oxygen demand-supply relation and might increase the risk of myocardial ischemia.
Zhao
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Department of Anesthesiology, Tohoku University School of Medicine, Sendai.
D000818:Animals; D001340:Autonomic Nerve Block; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology* / Q000628:therapy; D004285:Dogs; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption; D013233:Stellate Ganglion