title: Isolation of a novel RFamide peptide from the midgut of the American cockroach, Periplaneta americana.
abstract: In insects (FM)RFamide-immunoreactive endocrine cells are ubiquitously present in the midgut, but the identity of the peptide(s) produced by these cells is unknown. The major RFamide-immunoreactive peptide from the midgut of the American cockroach, Periplaneta americana, was isolated and identified as Ala-Asn-Arg-Ser-Leu-Arg-Leu-Arg-Pheamide. This is a novel member of an arthropod peptide family, previously known only from mosquitoes and horseshoe crabs. Its abundance in the midgut suggests that it plays an important function in digestion.
authors.affiliation: Department of Entomology, University of Arizona, Tucson 85721, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Veenstra
authors.forename: G
authors.initials: G
authors.lastname: Lambrou
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004797:Enzyme-Linked Immunosorbent Assay; D007422:Intestines / Q000737:chemistry; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry / Q000302:isolation & purification*; D010526:Periplaneta / Q000737:chemistry*
chemical_list: D009479:Neuropeptides; C058047:arginylphenylalaninamide