Parenteral copper and selenium supplementation of sheep on legume-grass pastures: biochemical and production responses in lambs to maternal treatment.
Liver and kidney copper (Cu) and selenium (Se) concentrations were studied over a 7-month period after parenteral supplementation using Cu heptonate and barium (Ba) selenate in 44 8-month-old South African (SA) Mutton Merino wethers. Responses in plasma Cu and blood Se concentrations, as well as fecundity were also measured in a breeding flock of SA Mutton Merino ewes for 3 consecutive years. The effect of maternal supplementation with Cu and Se was assessed in terms of biochemical parameters and production responses in 654 lambs produced by these ewes. Parenteral treatments with Cu and Se raised liver and kidney concentrations (P < or = 0.05) for up to 7 months in wethers under conditions where liver Cu and Se respectively declined to concentrations below 30 mg/kg DM and 300 micrograms/kg dry matter (DM) in spring. Plasma Cu concentrations of breeding ewes which received Cu heptonate were increased (P < or = 0.05) by 18% relative to the control group in which concentrations declined to 91 micrograms/dl during late pregnancy. Blood Se concentrations of control ewes exceeded 200 ng/ml, and were unaffected by parenteral Se supplementation. Survival of progeny of Cu heptonate treated ewes tended (P < or = 0.10) to be improved by 13% (0.68 vs 0.60). This tendency was accompanied by generally higher (P < or = 0.10) plasma Cu concentrations of these lambs relative to control lambs at 10 - 20 and 45 - 55 d of age. Lambs of Cu supplemented ewes that died prior to weaning, had higher (P < or = 0.05) liver Cu concentrations than control group contemporaries.(ABSTRACT TRUNCATED AT 250 WORDS)
Van Niekerk
F E
FE
Department of Human and Animal Physiology, University of Stellenbosch, Republic of South Africa.
Cloete
S W
SW
Van der Merwe
G D
GD
Heine
E W
EW
Scholtz
A J
AJ
D000818:Animals; D017609:Barium Compounds / Q000378:metabolism / Q000494:pharmacology*; D003300:Copper / Q000378:metabolism / Q000494:pharmacology*; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D012098:Reproduction / Q000187:drug effects*; D064586:Selenic Acid; D018036:Selenium Compounds / Q000378:metabolism / Q000494:pharmacology*; D012756:Sheep / Q000254:growth & development*
D017609:Barium Compounds; D018036:Selenium Compounds; D003300:Copper; D064586:Selenic Acid; C042078:barium selenate