Uterine fluid human decidua-associated protein 200 and implantation after embryo transfer.
Uterine fluid samples from 109 patients undergoing in-vitro fertilization and embryo transfer were obtained so as to examine the relationship between the uterine fluid concentration of human decidua-associated protein (hDP) 200 and the implantation rate. The sampling was performed on the day of embryo transfer with a Wallace catheter, used for the testing of cervical patency before embryo replacement. The implantation rate, as well as the pregnancy rate, demonstrated a significantly positive correlation with the concentration of hDP 200 in the uterine fluid, measured just before embryo transfer. These results indicate that hDP 200, identified as a rheumatoid factor secreted by the endometrium, may be involved in the implantation process.
Halperin
R
R
Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel.
Ron-El
R
R
Golan
A
A
Hadas
E
E
Schneider
D
D
Bukovsky
I
I
Herman
A
A
D003656:Decidua / Q000378:metabolism*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000032:analysis*; D012217:Rheumatoid Factor / Q000378:metabolism; D014599:Uterus / Q000378:metabolism*
D007136:Immunoglobulins; D011257:Pregnancy Proteins; C088113:decidua-associated protein 200; D012217:Rheumatoid Factor