A new enkephalinase inhibitor as an alternative to loperamide in the prevention of diarrhea induced by CPT-11.
Gonçalves
E
E
de Costa
L
L
Abigerges
D
D
Armand
J P
JP
D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D002166:Camptothecin / Q000009:adverse effects / Q000031:analogs & derivatives*; D002986:Clinical Trials as Topic; D003967:Diarrhea / Q000517:prevention & control*; D005260:Female; D006801:Humans; D000077146:Irinotecan; D008139:Loperamide / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015260:Neprilysin / Q000037:antagonists & inhibitors*; D016032:Randomized Controlled Trials as Topic; D015244:Thiorphan / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D008139:Loperamide; D000077146:Irinotecan; C049331:racecadotril; D015244:Thiorphan; D015260:Neprilysin; D002166:Camptothecin