title: Light treatment for sleep disorders: consensus report. III. Alerting and activating effects.
abstract: In addition to the well-established phase-shifting properties of timed exposure to bright light, some investigators have reported an acute alerting, or activating, effect of bright light exposure. To the extent that bright light interventions for sleep disturbance may cause subjective and/or central nervous system activation, such a property may adversely affect the efficacy of treatment. Data obtained from patient samples and from healthy subjects generally support the notion that exposure to bright light may be associated with enhanced subjective alertness, and there is limited evidence of objective changes (EEG, skin conductance levels) that are consistent with true physiological arousal. Such activation appears to be quite transient, and there is little evidence to suggest that bright light-induced activation interferes with subsequent sleep onset. Some depressed patients, however, have experienced insomnia and hypomanic activation following bright-light exposure.
authors.affiliation: Laboratory of Human Chronobiology, New York Hospital, Cornell University Medical College, White Plains, NY 10605, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Campbell
authors.forename: D J
authors.initials: DJ
authors.lastname: Dijk
authors.forename: Z
authors.initials: Z
authors.lastname: Boulos
authors.forename: C I
authors.initials: CI
authors.lastname: Eastman
authors.forename: A J
authors.initials: AJ
authors.lastname: Lewy
authors.forename: M
authors.initials: M
authors.lastname: Terman
mesh_terms: D001143:Arousal / Q000502:physiology; D001831:Body Temperature; D002940:Circadian Rhythm; D004569:Electroencephalography; D005712:Galvanic Skin Response; D006801:Humans; D008550:Melatonin / Q000378:metabolism; D010789:Phototherapy; D012893:Sleep Wake Disorders / Q000628:therapy*; D014851:Wakefulness; D014937:Work; D014940:Work Schedule Tolerance
chemical_list: D008550:Melatonin