title: Pupil size and reactivity following hydroxypropyl methylcellulose and sodium hyaluronate.
abstract: OBJECTIVE
  A prospective randomised clinical trial was set up to compare the effect of hydroxypropyl methylcellulose (Ocucoat) and sodium hyaluronate (Healonid) on pupil size and reactivity following their use in cataract surgery.
  
  
  METHODS
  Pupil measurements were recorded before and 6 weeks after surgery.
  
  
  RESULTS
  There was no significant difference between the two groups with respect to pupil size (p = 0.69, Mann-Whitney U test) nor with respect to reactivity (p = 0.99, Fischer's exact test). Ninety six per cent of the surgery was performed using phacoemulsification.
  
  
  CONCLUSIONS
  This trial suggests that both viscoelastic materials have similar effects on the pupil after their use in cataract surgery.
authors.affiliation: Croydon Eye Unit, Thornton Heath, Surrey.
authors.forename: J
authors.initials: J
authors.lastname: Eason
authors.forename: H C
authors.initials: HC
authors.lastname: Seward
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000379:methods*; D004548:Elasticity; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000494:pharmacology*; D065347:Hypromellose Derivatives; D008297:Male; D008747:Methylcellulose / Q000031:analogs & derivatives* / Q000494:pharmacology; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011680:Pupil / Q000187:drug effects*; D014783:Viscosity
chemical_list: D065347:Hypromellose Derivatives; D006820:Hyaluronic Acid; D008747:Methylcellulose