title: Exclusion mapping of the benign hereditary chorea gene from the Huntington's disease locus: report of a family.
abstract: A Greek family is presented in which seven members suffered from benign hereditary chorea (a rare autosomal dominant non-progressive chorea without dementia). All patients and three informative healthy relatives were submitted to DNA analysis using probes from loci linked to Huntington's disease. The results confirm one previous suggestion that these two disorders are not allelic and that they should be considered as two distinct genetic entities.
authors.affiliation: Department of Neurology, Athens University, Eginition Hospital, Greece.
authors.forename: C
authors.initials: C
authors.lastname: Yapijakis
authors.forename: E
authors.initials: E
authors.lastname: Kapaki
authors.forename: C
authors.initials: C
authors.lastname: Zournas
authors.forename: M
authors.initials: M
authors.lastname: Rentzos
authors.forename: D
authors.initials: D
authors.lastname: Loukopoulos
authors.forename: C
authors.initials: C
authors.lastname: Papageorgiou
mesh_terms: D000293:Adolescent; D000483:Alleles; D002819:Chorea / Q000208:ethnology / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D005799:Genes, Dominant / Q000235:genetics; D006115:Greece; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D006816:Huntington Disease / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D015342:DNA Probes