A clinicopathological and immunohistochemical analysis of primary oral mucosal melanoma.
Nine cases of primary oral mucosal melanoma in Caucasian patients were reviewed and the tumours analysed for expression of S100, HMB45, NKI/C3, HLA-DR, PCNA, cytokeratin and von Willebrand factor. The clinical, histopathological and immunohistochemical features were quite distinctive and our findings support previous suggestions that oral melanoma should be classified as a separate entity rather than as a sub-type of cutaneous melanoma.
Barrett
A W
AW
Joint Department of Oral Pathology, Eastman Dental Institute, London, UK.
Bennett
J H
JH
Speight
P M
PM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000032:analysis; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008543:Melanins / Q000032:analysis; D008545:Melanoma / Q000378:metabolism / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000378:metabolism / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis
D000951:Antigens, Neoplasm; D006684:HLA-DR Antigens; D008543:Melanins; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D018809:Proliferating Cell Nuclear Antigen; D009418:S100 Proteins