title: Vasovasostomy results in 66 patients related to obstructive intervals and serum agglutinin titres.
abstract: In this series we present the results of a retrospective analysis of 66 vasovasostomy procedures performed between 1983 and 1991. Obstructive intervals and serum antisperm antibodies were correlated with pregnancy and patency rates. With obstructive intervals of less than 5 years a patency rate of 100% (31/31) was obtained. Even more than 10 years after reversal, pregnancy occurred in 25% (2/8) of the patients. Preoperative serum antisperm antibodies were correlated with pregnancy rates. Patients with a high agglutinin titre of 1/64 obtained a pregnancy rate of 23% (3/13). Those men who had no circulating antisperm antibodies in their blood had a significantly better chance in obtaining pregnancy (pregnancy rate 80%). In this study we accounted for an overall pregnancy rate of 51.5% (34/66) versus an overall patency rate of 84.8% (56/66). Neither long obstructive intervals nor high antisperm antibody titres should dissuade a surgeon from performing a vasovasostomy procedure.
authors.affiliation: Department of Urology, De Wever Hospital, Heerlen, The Netherlands.
authors.forename: H J
authors.initials: HJ
authors.lastname: Vrijhof
authors.forename: K P
authors.initials: KP
authors.lastname: Delaere
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D013073:Sperm Agglutination; D013094:Spermatozoa / Q000276:immunology*; D013997:Time Factors; D016896:Treatment Outcome; D014669:Vasovasostomy
chemical_list: D001323:Autoantibodies