title: The enamelin (tuftelin) gene.
abstract: This paper reviews the primary structure, characteristics and possible function of tuftelin/enamelin protein. It describes the distribution of tuftelin in the ameloblast cell and in the extracellular enamel matrix, employing high resolution protein-A gold immunocytochemistry. The chromosomal localization of the human tuftelin gene and its possible involvement in autosomally linked Amelogenesis Imperfecta, the most common hereditary disease of enamel, is also discussed.
authors.affiliation: Department of Oral Biology, Hebrew University, Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Deutsch
authors.forename: A
authors.initials: A
authors.lastname: Palmon
authors.forename: L
authors.initials: L
authors.lastname: Dafni
authors.forename: J
authors.initials: J
authors.lastname: Catalano-Sherman
authors.forename: M F
authors.initials: MF
authors.lastname: Young
authors.forename: L W
authors.initials: LW
authors.lastname: Fisher
mesh_terms: D000565:Ameloblasts / Q000737:chemistry; D000567:Amelogenesis Imperfecta / Q000235:genetics; D000818:Animals; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D003746:Dental Enamel Proteins / Q000032:analysis / Q000737:chemistry / Q000235:genetics*; D005109:Extracellular Matrix / Q000737:chemistry; D006801:Humans
chemical_list: D003746:Dental Enamel Proteins; C038456:tuftelin