title: Age-related changes in the human mandibular condyle: a morphologic, radiologic, and histologic study.
abstract: OBJECTIVE
  This study determined the osteoarthrotic changes in the human mandibular condyle in relation to aging and the loss of dental occlusal contacts.
  
  
  METHODS
  Thirty-four condyles obtained at autopsy were studied morphologically, radiologically, and histologically.
  
  
  RESULTS
  With advancing age, the articular surface of the mandibular condyle morphologically showed severe degenerative changes. The condyles with these changes tended to be from the side of the mandible with minimal areas of occlusal contact. Radiographically, an irregularity of the cortical bone plate was most commonly seen in the fifth and sixth decades, whereas a polygonal or flattened structure was mainly observed after the seventh decade.
  
  
  CONCLUSIONS
  The histologic findings suggest that a decrease in the cellular components with advancing age may play a critical role in the development of degenerative changes.
authors.affiliation: Second Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ishibashi
authors.forename: Y
authors.initials: Y
authors.lastname: Takenoshita
authors.forename: K
authors.initials: K
authors.lastname: Ishibashi
authors.forename: M
authors.initials: M
authors.lastname: Oka
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002358:Cartilage, Articular / Q000473:pathology; D003766:Dental Occlusion; D005260:Female; D006801:Humans; D008297:Male; D008335:Mandibular Condyle / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D013705:Temporomandibular Joint Disorders / Q000000981:diagnostic imaging / Q000473:pathology*