title: [Morphologic study of mastocytes from skin biopsies in patients with non-systemic and systemic mastocytosis].
abstract: The authors describe morphologic changes in mastocytes in the picture of transmission electron microscopy (TEM) and skin changes in patients with urticaria pigmentosa (7 causes) and systemic mastocytosis (2 causes). The presented study analyzes the changes in the cellular membrane and cytoplasmic processes, intracytoplasmic membrane structures, mitochondria, granules, and nuclei of mastocytes in patients with systemic mastocytosis. The authors evaluate these cells as being atypical, respectively immature. The study discusses the malignization of these states. (Tab. 2, Fig. 8, Ref. 16.)
authors.affiliation: Klinika dermatovenerológie, Ustav histológie a embryológie, JLF UK v Martine, Slovakia.
authors.forename: J
authors.initials: J
authors.lastname: Péc
authors.forename: K
authors.initials: K
authors.lastname: Martinásková
authors.forename: K
authors.initials: K
authors.lastname: Belej
authors.forename: L
authors.initials: L
authors.lastname: Plank
authors.forename: L
authors.initials: L
authors.lastname: Lauko
authors.forename: M
authors.initials: M
authors.lastname: Péc
authors.forename: D
authors.initials: D
authors.lastname: Dobrota
authors.forename: V
authors.initials: V
authors.lastname: Filo
mesh_terms: D001706:Biopsy; D006801:Humans; D008407:Mast Cells / Q000648:ultrastructure*; D008415:Mastocytosis / Q000473:pathology*; D008854:Microscopy, Electron; D012867:Skin / Q000648:ultrastructure*; D014582:Urticaria Pigmentosa / Q000473:pathology*
vernacular_title: Morfologická stúdia mastocytov z kozných biopsií pacientov s nesystémovou a systémovou mastocytózou.