title: A single cytochrome P-450 system is involved in degradation of the herbicides EPTC (S-ethyl dipropylthiocarbamate) and atrazine by Rhodococcus sp. strain NI86/21.
abstract: During atrazine degradation by Rhodococcus sp. strain N186/21, N-dealkylated metabolites and an hydroxyisopropyl derivative are produced. The cytochrome P-450 system that is involved in degradation of thiocarbamate herbicides by strain N186/21 (I. Nagy, G. Schoofs, F. Compernolle, P. Proost, J. Vanderleyden, and R. De Mot, J. Bacteriol. 177:676-687, 1995) is also required for atrazine degradation. Atrazine-degrading activity was conferred on the atrazine-negative strains, mutant FAJ2027 of Rhodococcus sp. strain N186/21 and Rhodococcus erythropolis SQ1, upon transformation with the genes encoding the cytochrome P-450 system.
authors.affiliation: Department of Applied Plant Sciences, Catholic University of Leuven, Heverlee, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Nagy
authors.forename: F
authors.initials: F
authors.lastname: Compernolle
authors.forename: K
authors.initials: K
authors.lastname: Ghys
authors.forename: J
authors.initials: J
authors.lastname: Vanderleyden
authors.forename: R
authors.initials: R
authors.lastname: De Mot
mesh_terms: D000478:Alkylation; D001280:Atrazine / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001673:Biodegradation, Environmental; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism*; D004790:Enzyme Induction; D006540:Herbicides / Q000378:metabolism*; D012240:Rhodococcus / Q000201:enzymology* / Q000235:genetics / Q000378:metabolism; D012989:Soil Pollutants / Q000378:metabolism*; D013859:Thiocarbamates / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D006540:Herbicides; D012989:Soil Pollutants; D013859:Thiocarbamates; D003577:Cytochrome P-450 Enzyme System; D001280:Atrazine; C036251:EPTC