[Antitussive, expectorant and anti-asthmatic effects of Cynanchum glaucescens (Decne.) Hand. -Mazz].
The water, ethanol and ether extracts from Cynanchum glaucescems administrated orally showed significant antitussive effect in ammonia-induced cough model in mice. The water and ethanol extracts had obvious expectorant effect. The filtered solution of water decoction injected intraperitoneally could effectively prevent guinea pigs from asthma induced by acetulcholine and histamine mixture, and also inhibit the ear inflammation in mice caused by croton oil. All these effects showed close dose-effect relationship.
Liang
A
A
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
Xue
B
B
Yang
Q
Q
Li
Z
Z
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000633:toxicity; D000996:Antitussive Agents / Q000494:pharmacology* / Q000633:toxicity; D001993:Bronchodilator Agents / Q000494:pharmacology* / Q000633:toxicity; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000633:toxicity; D005100:Expectorants / Q000494:pharmacology* / Q000633:toxicity; D005260:Female; D008297:Male; D051379:Mice
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000996:Antitussive Agents; D001993:Bronchodilator Agents; D004365:Drugs, Chinese Herbal; D005100:Expectorants