title: Clinical abnormalities in adults with pancreaticobiliary maljunction with and without bile-duct dilatation.
abstract: OBJECTIVE
  To study clinical diseases associated with pancreaticobiliary maljunction with or without bile-duct dilatation.
  
  
  METHODS
  A retrospective study over 16 years.
  
  
  METHODS
  A single university surgical service in Japan.
  
  
  METHODS
  Thirty-three patients with pancreaticobiliary maljunction.
  
  
  METHODS
  Gallstones and cancer in patients with and without bile-duct dilatation.
  
  
  RESULTS
  Twenty-five patients had dilatation of the bile duct, 8 did not. Seven (28%) of the 25 patients with bile-duct dilatation had gallstones compared with 1 (12%) of the 8 patients with no dilatation. Seven (88%) of the 8 patients with no dilatation had carcinoma (all of the gallbladder), but only 3 (12%) of the 25 patients with bile-duct dilatation had carcinoma (1 of the gallbladder, 2 of the bile duct).
  
  
  CONCLUSIONS
  Prophylactic cholecystectomy is recommended for patients with pancreaticobiliary maljunction and no dilatation of the bile duct because of the high incidence of gallbladder cancer.
authors.affiliation: Second Department of Surgery, Kagoshima University, Faculty of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Nishimura
authors.forename: R
authors.initials: R
authors.lastname: Ishibe
authors.forename: M
authors.initials: M
authors.lastname: Yoshimine
authors.forename: S
authors.initials: S
authors.lastname: Ogata
authors.forename: A
authors.initials: A
authors.lastname: Taira
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001652:Bile Ducts / Q000002:abnormalities* / Q000601:surgery; D001661:Biliary Tract Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D002769:Cholelithiasis / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D000013:Congenital Abnormalities / Q000145:classification; D004108:Dilatation, Pathologic / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts / Q000002:abnormalities* / Q000601:surgery; D012189:Retrospective Studies