title: Nucleolar organizer regions (AgNORs) in in situ and invasive components of breast cancers.
abstract: The authors have studied the nucleolar organizer regions (AgNORs) (which reflect the cell kinetic activity) in the in situ and invasive components of breast cancers. The mean number of AgNORs/nucleus was 4.18 (s.d.: 1.35) in the in situ compartments and 5.41 (s.d.: 1.90) in invasive areas. The difference between these two groups is statistically significant. The higher proliferative activity in the infiltrating component might be due to the interaction between epithelial cells and the supporting stroma.
authors.affiliation: Institute of Oncology, Cluj-Napoca, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Răşinaru
authors.forename: C D
authors.initials: CD
authors.lastname: Olinici
authors.forename: M L
authors.initials: ML
authors.lastname: Blaga
mesh_terms: D001943:Breast Neoplasms / Q000648:ultrastructure*; D006801:Humans; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D016622:Silver Staining