title: Retrobulbar anesthesia with and without adrenaline in extracapsular cataract surgery. A prospective, randomized, double-blind study.
abstract: Seventy-five patients with senile cataract underwent a planned extracapsular cataract extraction. They were randomly divided into two groups, receiving retrobulbar anesthesia (4 ml lidocaine 2% and 250 IU hyaluronidase) with or without adrenaline. Patients in the adrenaline group had the lowest mean intraocular pressure after the retrobulbar injection (p < 0.02) and they required a shorter time of digital bulbar massage to reduce tension before surgery (p < 0.01). They also appeared to have a deeper anterior chamber during the first part of surgery, although the difference was not statistically significant. The duration of postoperative analgesia was significantly prolonged in patients receiving adrenaline. Different mechanisms explaining the effects of adrenaline in retrobulbar anesthesia are discussed.
authors.affiliation: Department of Ophthalmology, University of Bergen, Norway.
authors.forename: J
authors.initials: J
authors.lastname: Krohn
authors.forename: G
authors.initials: G
authors.lastname: Høvding
authors.forename: J H
authors.initials: JH
authors.lastname: Seland
authors.forename: H
authors.initials: H
authors.lastname: Aasved
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local / Q000379:methods*; D000867:Anterior Chamber / Q000187:drug effects; D002387:Cataract Extraction; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000008:administration & dosage*; D007429:Intraocular Pressure / Q000187:drug effects; D007910:Lenses, Intraocular; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009915:Orbit; D010149:Postoperative Pain / Q000188:drug therapy; D011446:Prospective Studies; D011680:Pupil / Q000187:drug effects
chemical_list: D008012:Lidocaine; D006821:Hyaluronoglucosaminidase; D004837:Epinephrine