Glomerular thrombosis predicts progression of glomerulonephritis: can we prevent progression?
The evidence for the important role of coagulation in the genesis and perpetuation of glomerular injury in diffuse proliferative lupus glomerulonephritis is reviewed. The importance of early detection is emphasized, so that treatment can be started before irreversible glomerular injury has occurred. Urinalysis and simple tests of renal function are effective means of early detection.
Pollak
V E
VE
Department of Internal Medicine, University of Cincinnati Medical Center, OH, USA.
D001706:Biopsy; D018450:Disease Progression; D005921:Glomerulonephritis / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control; D015432:Glomerulonephritis, Membranoproliferative; D006801:Humans; D007677:Kidney Function Tests; D008181:Lupus Nephritis; D013927:Thrombosis / Q000473:pathology / Q000503:physiopathology