title: Spinal cord ischemia diagnosed by MRI. Case report and review of the literature.
abstract: The purpose of this paper is to report a case of medullary ischemia diagnosed by MRI and to determine any MRI characteristics that may be useful for the diagnosis in the light of the published data. The patient was a 60 year-old male with hypertension and diabetes, referred to us for flaccid paraparesis and sphincter disorders of acute onset. Physical examination revealed, beside flaccid paraparesis, both superficial and deep hypoesthesia at L1 level and greater on the right. MRI showed a small area of signal hyperintensity on T2 weighted images and in proton density localized in the posterior part of the spinal cord at the level of T12 body. The patient was treated with oral antidiabetic, antiaggregant and antihypertensive drugs as well as neuromotor rehabilitation, and his clinical conditions improved; a control MRI, six months later, showed disappearance of the previous finding and only mild medullary atrophy at the level of the lesion. Medullary ischemia has been observed in a variety of pathological conditions (inflammatory, neoplastic, traumatic degenerative and iatrogenic), and most frequently involves the dorsal portion of the spinal cord. Four clinical-pathological manifestations of medullary ischemia have been described: infarction from occlusion of the anterior spinal artery; "patchy" or "lacunae infarction"; "transverse ischemic infarction"; selective ischemia in the regions of the posterior spinal arteries. A review of the literature yielded 61 cases of spinal ischemia diagnosed by MRI for a total number of 80 MRI scans, 12 of which were long-term controls.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Neurosciences, Rome University, La Sapienza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Fortuna
authors.forename: L
authors.initials: L
authors.lastname: Ferrante
authors.forename: M
authors.initials: M
authors.lastname: Acqui
authors.forename: G
authors.initials: G
authors.lastname: Trillò
mesh_terms: D001158:Arteries; D001284:Atrophy; D006801:Humans; D006987:Hypesthesia / Q000473:pathology; D007238:Infarction / Q000175:diagnosis / Q000473:pathology; D007511:Ischemia / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010291:Paresis / Q000473:pathology; D013116:Spinal Cord / Q000098:blood supply* / Q000473:pathology