title: [Cerebral space-occupying lesion in thrombocytosis].
abstract: We report a case of venous thrombosis presented as ischemic intracranial expanding lesion localized in the parietal lobe of a young man with essential thrombocytosis. As surgical intervention became necessary we were able to investigate the morphological changes by histology and immunocytochemistry. The almost exclusive venous manifestation of thrombosis most probably initiated by elevated amounts of platelets suggests altered blood flow conditions as the predominant factor. Surgical interventions in such conditions are rare and might only proceed in space-occupying lesions with clinical symptoms. Treatment with inhibitors of platelet aggregation under strict control of the patient is the therapy of choice.
authors.affiliation: Neurochirurgische Abteilung am Krankenhaus, Barmherzigen Brüder, Regensburg.
authors.forename: P
authors.initials: P
authors.lastname: Gruss
authors.forename: G
authors.initials: G
authors.lastname: Gerhart
authors.forename: J
authors.initials: J
authors.lastname: Schlegel
mesh_terms: D000328:Adult; D001241:Aspirin / Q000008:administration & dosage; D001760:Bleeding Time; D002550:Cerebral Veins / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D009336:Necrosis; D010296:Parietal Lobe / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D010974:Platelet Aggregation / Q000502:physiology; D013922:Thrombocytosis / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
chemical_list: D001241:Aspirin
vernacular_title: Cerebrale Raumforderung bei Thrombozytose.