Fallopian tube sperm perfusion has no advantage over intra-uterine insemination when used in combination with ovarian stimulation for the treatment of unexplained infertility.
In this prospective randomized study we treated 60 couples with unexplained infertility with a combination of ovarian stimulation and either intrauterine insemination (IUI) or fallopian sperm perfusion (FSP). In the IUI we used a volume of 0.5 ml of inseminate and in the FSP a volume of 4 ml. The demographic characteristics of the patients, the stimulation parameters and the sperm data were not statistically different between the two groups. The pregnancy rate per cycle was 16.2% in the IUI group and 14.5% in the FSP group and the pregnancy rate per woman was 40 and 36.7%, respectively (not statistically different). We conclude that IUI and FSP are equally effective in the treatment of couples with unexplained infertility.
Gregoriou
O
O
Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Greece.
Pyrgiotis
E
E
Konidaris
S
S
Papadias
C
C
Zourlas
P A
PA
D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007246:Infertility / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D011247:Pregnancy; D011446:Prospective Studies; D014599:Uterus
D006063:Chorionic Gonadotropin; D008596:Menotropins