Pathogenesis of epilepsy: the role of excitatory amino acids.
EAAs appear to have a major role in both the development and the propagation of seizures. However, since EAAs have an important role in learning and brain plasticity, it is important that future investigators study not only the antiepileptic and neuroprotective properties of EAA antagonists, but also their effects on learning, memory, and behavior.
Holmes
G L
GL
Department of Neurology, Harvard Medical School Children's Hospital, Boston, USA.
D000818:Animals; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000503:physiopathology*; D018846:Excitatory Amino Acids / Q000502:physiology*; D006801:Humans
D018846:Excitatory Amino Acids