title: [Does the basic therapy affect the development of secondary amyloidosis in rheumatoid arthritis?].
abstract: Anti-rheumatic drug treatments were studied in 260 patients from Finland and Russia suffering from rheumatoid arthritis (RA) with or without biopsy-proven secondary amyloidosis (RSA). Chloroquine was used for longer period in RSA group in Russia (p = 0.003) and in Finland (p = 0.06). In Finland chloroquine was used more often in the RSA group (p = 0.02), and sulphasalazine (p = 0.02), D-penicillamine (p = 0.03) and cytotoxics (p = 0.04) in the control group. The role of therapy in the prevention of RSA in chronic inflammation is discussed.
authors.forename: T B
authors.initials: TB
authors.lastname: Prokaeva
authors.forename: Z S
authors.initials: ZS
authors.lastname: Alekberova
authors.forename: S G
authors.initials: SG
authors.lastname: Radenska-Lopovok
authors.forename: S
authors.initials: S
authors.lastname: Tiitinen
authors.forename: K
authors.initials: K
authors.lastname: Kaarela
authors.forename: H
authors.initials: H
authors.lastname: Kautiainen
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016009:Chi-Square Distribution; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D012426:Russia; D018709:Statistics, Nonparametric; D013997:Time Factors
chemical_list: D018501:Antirheumatic Agents
vernacular_title: Vliiaet li terapiia bazisnogo riada na razvitie vtorichnogo amiloidoza pri revmatoidnom artrite?