[The clinical importance of determining fibronectin and the activity of proteolysis inhibitors in patients with bronchial asthma complicated by pulmonary emphysema].
Examinations of 27 inpatients with infection-dependent bronchial asthma complicated by pulmonary emphysema revealed low levels of fibronectin and alpha proteinase inhibitor, which were in a positive correlation. The said deficiency was stable in asthmatics and was virtually unchanged as remission was attained. Hence, we may propose that the said changes may underlie not only the development, but stabilization and progress of pulmonary emphysema in patients with the infection-dependent variant of bronchial asthma.
Okopnaia
L M
LM
Glazatova
T M
TM
Zorin
V N
VN
Vassim
K
K
Padalka
I M
IM
D001249:Asthma / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D011480:Protease Inhibitors / Q000097:blood*; D011656:Pulmonary Emphysema / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D000515:alpha 1-Antitrypsin / Q000032:analysis
D005353:Fibronectins; D011480:Protease Inhibitors; D000515:alpha 1-Antitrypsin
Klinicheskoe znachenie opredeleniia fibronektina i aktivnosti ingibitorov proteoliza u bol'nykh bronkhial'noĭ astmoĭ, oslozhnennoĭ émfizemoĭ legkikh.