title: Changes in postocclusive reactive hyperaemic values as measured with laser Doppler fluxmetry after infrainguinal arterial reconstructions.
abstract: OBJECTIVE
  The aim of the present study was to evaluate microcirculartory changes of the postocclusive reactive hyperaemia test measured with Laser Doppler fluxmetry to detect results of arterial reconstructions.
  
  
  METHODS
  Prospective open study.
  
  
  METHODS
  Vascular laboratory of a University Hospital.
  
  
  METHODS
  Sixty patients with peripheral arterial occlusive disease who underwent infrainguinal reconstruction were examined the day before and 1-2 days after surgery.
  
  
  METHODS
  The values were obtained during postocclusive reactive hyperaemia induced by release of a 3 min arterial occlusion with a cuff at ankle level with the laser Doppler probe placed dorsally on the first toe. The alterations after surgery in these hyperaemia parameters were compared to changes in ankle/brachial index and clinical improvement at 30 days postoperatively.
  
  
  RESULTS
  Patients improved by surgery according to ankle/brachial index had significantly reduced time to peak (p < 0.001) and significantly increased resting flux value (p < 0.05) and peak flux value (p < 0.05). There was a significant correlation between the change after surgery in time to peak flux and increment of ankle/brachial index (r = 0.63, p < 0.001).
  
  
  CONCLUSIONS
  Changes in reactive hyperaemia values as measured with laser Doppler fluxmetry, especially the time to peak flux, seem to detect circulatory changes caused by arterial reconstructions.
authors.affiliation: Department of Surgery Karolinska Hospital, Stockholm, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Wahlberg
authors.forename: P
authors.initials: P
authors.lastname: Olofsson
authors.forename: J
authors.initials: J
authors.lastname: Swendenborg
authors.forename: B
authors.initials: B
authors.lastname: Fagrell
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000842:Ankle / Q000098:blood supply / Q000000981:diagnostic imaging; D001132:Arm / Q000098:blood supply / Q000000981:diagnostic imaging; D001157:Arterial Occlusive Diseases / Q000503:physiopathology* / Q000601:surgery*; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006940:Hyperemia / Q000503:physiopathology*; D017078:Laser-Doppler Flowmetry; D007866:Leg / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011446:Prospective Studies; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D014034:Toes / Q000098:blood supply; D018608:Ultrasonography, Doppler