[Experimental study on anti-duck hepatitis B viral effect of Phyllanthus urinaria of different areas and combined therapy with other drugs].
The duck hepatitis B virus model was treated with phyllanthus urinaria of different area and combined with Sophora flavesceus as well as ciprofloxacin once a day for one month, the results indicated: Guangxi and Yunnan Phyllanthus could lower the serum DHBV DNA significantly (P < 0.05), but Chongqing Phyllanthus couldn't. And the amount of serum DHBV DNA rose a week after stopping of Yunnan Phyllanthus. The antiviral effect of Guangxi Phyllanthus combined with ciprofloxacin seems to be strengthened (P < 0.05).
Chen
Y X
YX
Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Sichuan.
Guo
S H
SH
Zhang
D F
DF
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004279:DNA, Viral / Q000097:blood; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004372:Ducks; D018347:Hepadnaviridae Infections / Q000188:drug therapy*; D015611:Hepatitis B Virus, Duck / Q000187:drug effects* / Q000235:genetics; D011201:Poultry Diseases / Q000188:drug therapy*; D013045:Species Specificity
D000998:Antiviral Agents; D004279:DNA, Viral; D004365:Drugs, Chinese Herbal; D002939:Ciprofloxacin