title: Transcription of spoIVB is the only role of sigma G that is essential for pro-sigma K processing during spore formation in Bacillus subtilis.
abstract: Activation of pro-sigma K processing in the mother cell at late stages of sporulation in Bacillus subtilis requires the presence of active sigma G in the forespore. Placing the spoIVB gene under the control of sigma F, the early forespore transcription factor, allows sigma K to become active in the absence of sigma G. Therefore, transcription of spoIVB is the only role of sigma G that is essential for the signaling pathway between sigma G and sigma K.
authors.affiliation: Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia 19104-6076, USA.
authors.forename: M
authors.initials: M
authors.lastname: Gomez
authors.forename: S
authors.initials: S
authors.lastname: Cutting
authors.forename: P
authors.initials: P
authors.lastname: Stragier
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D008565:Membrane Proteins; D011498:Protein Precursors / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D012808:Sigma Factor / Q000378:metabolism*; D013171:Spores, Bacterial / Q000235:genetics / Q000254:growth & development; D013997:Time Factors; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins; D011498:Protein Precursors; D012808:Sigma Factor; D014157:Transcription Factors; C084190:sigma K; C088067:spoIV protein, Bacillus megaterium; C079274:RNA polymerase sigma G; D012321:DNA-Directed RNA Polymerases