Metastatic adenocarcinoma to the retina in a patient with Muir-Torre syndrome.
OBJECTIVE
A 74-year-old woman had multiple tumors including a retinal mass. Her medical history included cutaneous sebaceous adenomas, adenocarcinoma of the breast, and colonic adenocarcinoma. Her involved eye became painful and was enucleated.


CONCLUSIONS
Examination of the enucleated eye disclosed metastatic adenocarcinoma to the retina with retinal detachment. The patient described has a retinal metastasis of an unknown primary tumor site with Muir-Torre syndrome, characterized by an association of a sebaceous gland tumor with an internal malignancy.
Spraul
C W
CW
Department of Ophthalmology, University Eye Hospital of Ulm, Germany.
Lang
G E
GE
Grossniklaus
H E
HE
Lang
G K
GK
D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000236:Adenoma / Q000473:pathology*; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology*; D015353:Eye Enucleation; D005142:Eyelid Neoplasms; D005260:Female; D006801:Humans; D007636:Keratoacanthoma; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000209:etiology / Q000473:pathology; D012164:Retinal Diseases / Q000473:pathology / Q000601:surgery; D012626:Sebaceous Gland Neoplasms / Q000473:pathology*; D013577:Syndrome