Maternal and perinatal complications in triplet compared with twin pregnancy.
OBJECTIVE
To compare maternal and perinatal complications in triplet and twin pregnancies.


METHODS
Case-controlled study in the setting of a University Hospital. Each pregnancy of a consecutive series of 40 triplet pregnancies of 20 weeks or more was matched for parity and maternal age with two sets of twins delivered in the same year. Primary end points of the analysis were maternal complications and perinatal outcome.


RESULTS
Of the triplets 82% and of the twins 36% were a result of assisted reproduction. Pre-term labor occurred significantly more often in triplet than in twin gestation. Triplets had a significantly lower median birth-weight (1478 vs. 2030 g) and gestational age at delivery (32 vs. 35.5 weeks). The mean neonatal hospital stay was significantly longer in triplets, mainly related to the lower birth-weight, but there was no significant difference between triplets and twins in the incidence of major neonatal complications.


CONCLUSIONS
This data of the anticipated perinatal outcome in triplet and twin pregnancies may be used to counsel women with a triplet pregnancy considering selective reduction to twins. All methods of assisted reproduction should aim at prevention of multifetal gestation.
Santema
J G
JG
Department of Obstetrics and Gynecology, Erasmus University School of Medicine and Health Sciences, Rotterdam, The Netherlands.
Bourdrez
P
P
Wallenburg
H C
HC
D001724:Birth Weight; D016022:Case-Control Studies; D002585:Cesarean Section; D005260:Female; D005313:Fetal Death; D005865:Gestational Age; D006801:Humans; D007744:Obstetric Labor Complications; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012099:Reproductive Techniques; D014310:Triplets; D014427:Twins