title: Cancer of the mobile tongue in Mexico. A retrospective study of 170 patients.
abstract: Histological reports of 170 patients with cancer of the mobile tongue between 1977 and 1989 were identified at the Instituto Nacional de Cancerología (INCan), in Mexico City. Demographic, clinical and histological information was retrospectively reviewed. Chi-square, Student's t-test and Wilcoxon rank-sum test were applied for comparisons, and Kaplan-Meier curves, log-rank test and Cox proportional hazards for survival analysis. Of the 161 patients with mobile tongue squamous cell carcinoma (MTSCC), 104 (65%) were males and 57 (35%) were females. The mean age was 60 years old (range 19-91). T1 and T2 lesions comprised 35%, T3 and T4 lesions 65%. There was a statistically significant association between size of the tumour and lymph node involvement (P < 0.0001). The proportion of cases with advanced disease was 80% for males and 57% for females (P = 0.008). The 5-year survival rate was 16% (CI 10.2-22.8%). Cancer of the mobile tongue in Mexico still has a poor prognosis. Efforts should be made to reduce the delay in diagnosis of MTSCC, in order to increase the cure rates and improve the quality of life of the patients.
authors.affiliation: Universidad Autonoma Metropolitana-Xochimilco, Department of Health Care, Mexico.
authors.forename: V
authors.initials: V
authors.lastname: Ramirez-Amador
authors.forename: L
authors.initials: L
authors.lastname: Esquivel-Pedraza
authors.forename: F J
authors.initials: FJ
authors.lastname: Ochoa-Carrillo
authors.forename: A
authors.initials: A
authors.lastname: Cuapio-Ortiz
authors.forename: M
authors.initials: M
authors.lastname: Frias-Mendivil
authors.forename: A
authors.initials: A
authors.lastname: Meneses-Garcia
authors.forename: G
authors.initials: G
authors.lastname: Sanchez-Mejorada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D012189:Retrospective Studies; D017678:Sex Distribution; D014062:Tongue Neoplasms / Q000453:epidemiology* / Q000473:pathology