title: Use of mineral trioxide aggregate for repair of furcal perforations.
abstract: The histologic response to intentional perforation in the furcations of 28 mandibular premolars in seven dogs was investigated. In half the teeth, the perforations were repaired immediately with either amalgam or mineral trioxide aggregate; in the rest the perforations were left open to salivary contamination before repair. All repaired perforations were left for 4 months before histologic examination of vertical sections through the site. In the immediately repaired group, all the amalgam specimens were associated with inflammation, whereas only one of six with mineral trioxide aggregate was; further, the five noninflamed mineral trioxide aggregate specimens had some cementum over the repair material. In the delayed group, all the amalgam specimens were associated with inflammation; in contrast only four of seven filled with the aggregate were inflamed. On the basis of these results, it appears that mineral trioxide aggregate is a far more suitable material than amalgam for perforation repair, particularly when used immediately after perforation.
authors.affiliation: Department of Conservative Dental Surgery, UMDS, London, England.
authors.forename: T R
authors.initials: TR
authors.lastname: Ford
authors.forename: M
authors.initials: M
authors.lastname: Torabinejad
authors.forename: D J
authors.initials: DJ
authors.lastname: McKendry
authors.forename: C U
authors.initials: CU
authors.lastname: Hong
authors.forename: S P
authors.initials: SP
authors.lastname: Kariyawasam
mesh_terms: D017607:Aluminum Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D017610:Calcium Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D003723:Dental Amalgam / Q000494:pharmacology; D003786:Dental Pulp Cavity / Q000293:injuries*; D004285:Dogs; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D010087:Oxides / Q000494:pharmacology* / Q000627:therapeutic use; D012387:Root Canal Filling Materials / Q000494:pharmacology* / Q000627:therapeutic use; D017640:Silicates / Q000494:pharmacology* / Q000627:therapeutic use; D018677:Tooth Injuries / Q000628:therapy; D014092:Tooth Root / Q000293:injuries*; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000517:prevention & control
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D003723:Dental Amalgam