title: Amphitoxin, a new high molecular weight antifeedant pyridinium salt from the Caribbean sponge Amphimedon compressa.
abstract: A new polymeric pyridinium alkaloid named amphitoxin [2] has been isolated from Amphimedon compressa, and its structure determined by spectroscopic analysis. In laboratory feeding experiments, crude extracts and purified amphitoxin [2] from A. compressa at lower than natural concentration levels effectively deterred feeding of a generalist predatory Caribbean reef fish, Thalassoma bifasciatum.
authors.affiliation: Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Albrizio
authors.forename: P
authors.initials: P
authors.lastname: Ciminiello
authors.forename: E
authors.initials: E
authors.lastname: Fattorusso
authors.forename: S
authors.initials: S
authors.lastname: Magno
authors.forename: J R
authors.initials: JR
authors.lastname: Pawlik
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D005247:Feeding Behavior / Q000187:drug effects*; D005399:Fishes / Q000502:physiology; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D008970:Molecular Weight; D011161:Porifera / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D008387:Marine Toxins; D011726:Pyridinium Compounds; C094708:amphitoxin