Pre-eclampsia and trisomy 13.
A 41 year old multiparous woman with an uncomplicated obstetric history was referred because of pre-eclampsia. As ultrasonic examination revealed severe IUGR and multiple congenital anomalies, trisomy 13 was suspected and confirmed by amniocentesis. This chromosomal anomaly should be suspected in cases where pre-eclampsia is associated with abnormal fetal morphology.
Heydanus
R
R
Department of Obstetrics and Gynaecology, University Hospital Ghent, Belgium.
Defoort
P
P
Dhont
M
M
D000328:Adult; D000649:Amniocentesis; D002882:Chromosomes, Human, Pair 13; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging; D006801:Humans; D011225:Pre-Eclampsia / Q000235:genetics*; D011247:Pregnancy; D014314:Trisomy; D016216:Ultrasonography, Prenatal