title: [Pulmonary valvuloplasty in childhood: the immediate results and long-term follow-up].
abstract: BACKGROUND
  Pulmonary balloon valvuloplasty is the treatment of choice of pulmonary valve stenosis, but early results and long-term follow-up in a numerous and homogeneous pediatric population are poorly known.
  
  
  METHODS
  From April 1984 to April 1994, 202 valvuloplastic procedures were performed in 197 patients (age 52.5 +/- 150 months). Hemodynamic data were analysed according with valvular morphology and patient's age at procedure. During a follow-up period of 50 +/- 38 months, clinical and instrumental data were collected.
  
  
  RESULTS
  After pulmonary valvuloplasty RV pressure decreased from 86 +/- 28 to 41 +/- 21 mm Hg (p < 0.001), transvalvular pressure gradient from 67 +/- 27 to 24 +/- 14 mm Hg (p < 0.001) and RV/LV pressure ratio from 1.01 +/- 0.29 to 0.53 +/- 0.19 (p < 0.001). Overall success rate was 95% (187/197 patients). Pulmonary valve dysplasia and/or annulus hypoplasia significantly influenced the efficacy of the procedure and/or the recurrence of valvar stenosis (18.8% vs 2.7%, p < 0.01). During the follow-up period, clinical examination was unremarkable, and transvalvular pressure gradient did not change (23 +/- 9 vs 24 +/- 6 mm Hg at discharge, p = NS). Freedom from restenosis was 98% at 3 years and 96% at 5 and 10 years.
  
  
  CONCLUSIONS
  Pulmonary balloon valvuloplasty is a safe, effective and possibly definitive treatment for isolated pulmonary valve stenosis in infants and children. Age at valvuloplasty does not influence the success of the procedure, as opposed to valvular dysplasia and/or annulus hypoplasia that positively relate to the need of surgical valvotomy and/or the recurrence of stenosis during a long-term follow-up. In conclusion, prognosis of the majority of infants and children after a successful valvuloplasty is excellent during a long-term follow-up period.
authors.affiliation: Ospedale Bambino Gesù, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Santoro
authors.forename: R
authors.initials: R
authors.lastname: Formigari
authors.forename: L
authors.initials: L
authors.lastname: Pasquini
authors.forename: A
authors.initials: A
authors.lastname: De Zorzi
authors.forename: L
authors.initials: L
authors.lastname: Ballerini
mesh_terms: D000293:Adolescent; D002404:Catheterization / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009634:Noonan Syndrome / Q000503:physiopathology / Q000628:therapy; D011664:Pulmonary Valve / Q000503:physiopathology; D011666:Pulmonary Valve Stenosis / Q000503:physiopathology / Q000628:therapy; D013997:Time Factors
vernacular_title: Valvuloplastica polmonare in età pediatrica: risultati immediati e follow-up a lungo termine.