title: Correlation distance measurements of the female breast.
abstract: Ultrasonic waves propagating through soft tissue experience wavefront distortion. Adaptive wavefront compensation algorithms attempt to correct such distortion. A valuable design parameter is the isoplanatic patch size of the imaging medium. Its lateral extent is the FWHM of the correlation function. The range extent is defined similarly. The significance of the isoplanatic patch is that a new wavefront correction vector must be obtained whenever the ultrasound beam is moved a patch length. This paper reports measurements of wavefront correlation functions as well as statistics of the lateral correlation distance rho d (half the FWHM) within the female breast obtained from a population of 22 women (44 breasts) and measured at 3 and 4 MHz with a large acoustic aperture (9.6 cm). A set of complex wavefronts radiated from single pointlike sources was measured from the opposing side of the breast. The propagation distance was 12 cm. rho d is the distance between two sources at which the correlation between their wavefronts drops to 0.5. The mean value at 3 MHz was found to be less than 1.5 mm for the premenopausal dense breast, 2.5 mm for the premenopausal fatty breast, and 2.0 mm for the postmenopausal breast. The mean value dropped by a factor of 2 at 4 MHz for a group consisting of premenopausal fatty and postmenopausal breasts.
authors.affiliation: Valley Force Research Center, Moore School of Electrical Engineering, University of Pennsylvania, Philadelphia 19104, USA.
authors.forename: Q
authors.initials: Q
authors.lastname: Zhu
authors.forename: B D
authors.initials: BD
authors.lastname: Steinberg
authors.forename: R
authors.initials: R
authors.lastname: Arenson
mesh_terms: D000328:Adult; D001940:Breast / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008962:Models, Theoretical; D017698:Postmenopause; D017697:Premenopause