title: Peri-rolandic and fronto-parietal components of scalp-recorded giant SEPs in cortical myoclonus.
abstract: Scalp topography of giant SEPs to median nerve stimulation was studied in 4 patients with cortical myoclonus of various etiology. The positive peak (P30) at the contralateral parietal area was simultaneously accompanied by a negative peak at the frontal area (N30), and at least one of these two peaks was enhanced in 2 patients. Another positive peak (P25) and a negative peak (N35) were also identified at the peri-rolandic area with different latency from P30 and N30, respectively, in all patients. N35 was enhanced in 3 patients, and P25 in 2 patients. It is concluded that, as seen in normal subjects, tangential (P30-N30) and radial (P25 and N35) components of SEPs are most likely distinguishable in giant SEPs, and that either one or both of those components is enhanced in different ways depending on the patients.
authors.affiliation: Department of Brain Pathophysiology, Kyoto University School of Medicine, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ikeda
authors.forename: H
authors.initials: H
authors.lastname: Shibasaki
authors.forename: T
authors.initials: T
authors.lastname: Nagamine
authors.forename: X
authors.initials: X
authors.lastname: Xu
authors.forename: K
authors.initials: K
authors.lastname: Terada
authors.forename: T
authors.initials: T
authors.lastname: Mima
authors.forename: R
authors.initials: R
authors.lastname: Kaji
authors.forename: I
authors.initials: I
authors.lastname: Kawai
authors.forename: Y
authors.initials: Y
authors.lastname: Tatsuoka
authors.forename: J
authors.initials: J
authors.lastname: Kimura
mesh_terms: D000293:Adolescent; D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000209:etiology / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010296:Parietal Lobe / Q000503:physiopathology*