title: Cloning and sequence analysis of a cDNA encoding human syntaxin 1A, a polypeptide essential for exocytosis.
abstract: A clone encoding human syntaxin 1A was isolated and sequenced from a human brain library. The deduced sequence encodes a 288-amino-acid (aa) protein that presumably plays a critical role in neurotransmitter exocytosis and is 98.0% identical to the aa sequence of rat syntaxin 1A.
authors.affiliation: Department of Medicine, Jefferson Medical College, Philadelphia, PA 19107, USA.
authors.forename: R
authors.initials: R
authors.lastname: Zhang
authors.forename: A B
authors.initials: AB
authors.lastname: Maksymowych
authors.forename: L L
authors.initials: LL
authors.lastname: Simpson
mesh_terms: D000595:Amino Acid Sequence; D000954:Antigens, Surface / Q000235:genetics*; D001483:Base Sequence; D001692:Biological Transport; D001923:Brain Chemistry / Q000235:genetics*; D005089:Exocytosis; D015723:Gene Library; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics*; D018377:Neurotransmitter Agents / Q000378:metabolism; D050765:Qa-SNARE Proteins; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D050827:Syntaxin 1
chemical_list: D000954:Antigens, Surface; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D018377:Neurotransmitter Agents; D050765:Qa-SNARE Proteins; C494212:STX1A protein, human; C494213:Stx1a protein, rat; D050827:Syntaxin 1