Functional magnetic resonance imaging of the human motor cortex.
Functional magnetic resonance (MR) imaging of the brain was performed during motor task activation in five normal subjects and a patient with meningioma using conventional fast low-angle shot sequences and a 2.0 T system. A high intensity area in the motor cortex was observed in all normal subjects. Single-slice studies showed the right-sided finger task produced an increase of 1.9-23.5% (6.67 +/- 4.36%) in the signal intensity of the left motor cortex, while the left-sided finger task increased the signal by 1.5-18.2% (6.09 +/- 3.34%) in the right motor cortex. There was no significant difference between the sides. Multiple-slice studies also showed the activated motor cortex as a high intensity area. The maximum signal intensity increase in the activated motor area was 11.0% for the left motor cortex and 8.8% for the right motor cortex. There was no significant difference between the sides. Preoperative mapping of the patient with meningioma showed that the motor cortex was displaced posteriorly by the tumor. Functional MR imaging is possible with a standard MR imaging system and conventional gradient echo sequences. Useful clinical information can be obtained by preoperative mapping of the motor cortex.
Sasahira
M
M
Department of Neurosurgery, Faculty of Medicine, University of Kagoshima, Japan.
Asakura
T
T
Niiro
M
M
Haruzono
A
A
Hirakawa
W
W
Matsumoto
T
T
Fujimoto
T
T
D000344:Afferent Pathways / Q000503:physiopathology; D001143:Arousal / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D004292:Dominance, Cerebral / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000503:physiopathology*; D008579:Meningioma / Q000175:diagnosis / Q000503:physiopathology*; D009043:Motor Activity / Q000502:physiology*; D009044:Motor Cortex / Q000503:physiopathology*; D012016:Reference Values
D006454:Hemoglobins; C100003:deoxyhemoglobin