Proto-oncogenes and oncogenes in epidermal neoplasia.
This review briefly will focus on the role of selected proto-oncogenes and their activated forms during the regulation of cell proliferation, cell death and tumor formation in the epidermis. In addition, the multiple and complex functions of these proteins in normal as well as transformed cells will be discussed.
Simon
M M
MM
Center of Applied Genetics, BOKU-Vienna, Austria.
Sliutz
G
G
Luger
T A
TA
D000818:Animals; D017209:Apoptosis / Q000235:genetics; D002453:Cell Cycle / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D003043:Cocarcinogenesis; D015972:Gene Expression Regulation, Neoplastic; D017781:Genes, Immediate-Early; D016147:Genes, Tumor Suppressor; D016158:Genes, p53; D011905:Genes, ras; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D051379:Mice; D009363:Neoplasm Proteins / Q000502:physiology; D009381:Neoplasms, Radiation-Induced / Q000235:genetics; D009857:Oncogenes; D011519:Proto-Oncogenes; D012878:Skin Neoplasms / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology
D006133:Growth Substances; D009363:Neoplasm Proteins; D014157:Transcription Factors