title: Hepatic tumors: magnetization transfer MR imaging with gadolinium enhancement.
abstract: Thirty patients with 15 hepatocellular carcinomas, 10 metastases, four hemangiomas, and one cholangiocarcinoma underwent magnetic resonance imaging at 1.5 T with T1-weighted, T2-weighted spin-echo (SE) images, gradient-echo (GRE) magnetization transfer (MT) images, and gadolinium-enhanced T1-weighted SE and MT-GRE images. The MT effect and lesion-liver contrast-to-noise ratio (C/N) were calculated and visual assessment (qualitative analysis) performed for unenhanced and enhanced MT-GRE images and enhanced T1-weighted SE images. The C/N values for hepatic adenocarcinomas (seven metastases and one cholangiocarcinoma) and hemangiomas were larger for enhanced MT-GRE images (adenocarcinoma, 8.4 +/- 2.3 [P < .01]; hemangioma 24 +/- 2.1 [P < .05]) than for enhanced GRE images (5.0 +/- 1.9 and 18 +/- 2.7, respectively). These enhancing tumors had the highest scores in the qualitative analysis. Enhanced MT-GRE images showed no advantage for depiction of hepatocellular carcinomas relative to the other images.
authors.affiliation: Department of Radiology, University of Tsukuba, Ibaraki, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Onaya
authors.forename: H
authors.initials: H
authors.lastname: Yoshioka
authors.forename: Y
authors.initials: Y
authors.lastname: Itai
authors.forename: M
authors.initials: M
authors.lastname: Niitsu
authors.forename: I
authors.initials: I
authors.lastname: Anno
authors.forename: T
authors.initials: T
authors.lastname: Okumura
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary; D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis; D018281:Cholangiocarcinoma / Q000175:diagnosis; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006391:Hemangioma / Q000175:diagnosis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests
chemical_list: D003287:Contrast Media; D005682:Gadolinium