[Vasculopathy in patients with systemic lupus erythematosus and the antiphospholipid syndrome].
Clinicomorphological examination covered 100 patients with confirmed SLE: 79 with concomitant APS (group 1), 21 free of APS (group 2). In group 1 thrombolytic complications occurred in 75%, in group 2- in 13%. The recurrences were more frequent in group 1. Overall percentage of arterial and venous thromboses was approximately the same. According to biopsy and autopsy 2 kinds of morphological changes were found: typical for SLE and APS. Morphological specificity of APS manifested with proliferative and thrombotic changes in both arteries and veins.
Alekberova
Z S
ZS
Reshetniak
T M
TM
Rodenska-Lopovok
S G
SG
Aleksandrova
E N
EN
Kalashnikova
L A
LA
Nasonov
E L
EL
Mach
E S
ES
Nasonova
V A
VA
D000293:Adolescent; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D012867:Skin / Q000473:pathology; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology
Vaskulopatiia u bol'nykh sistemnoĭ krasnoĭ volchankoĭ s antifosfolipidnym sindromom.