title: [Diffuse pulmonary infiltration at the onset of Waldenström's disease].
abstract: The case of an 52 years old female presenting dyspnea and pulmonary infiltration is reported. A transbronchial biopsy showing a lymphomatous infiltrate with immunohistochemistry using anti-IgM antibody on paraffine embedded section helped to diagnose. A monoclonal increase in seric immunoglobin M, led to the diagnosis of Waldrenström's macroglobulinemia. An initial therapeutic response to Chlorambucil was obtained. But a quick recurrence was observed, with an increase of seric IgG.
authors.affiliation: Service de Pneumologie, Hôpital A. Michallon, CHU Grneoble.
authors.forename: G
authors.initials: G
authors.lastname: Devouassoux
authors.forename: C
authors.initials: C
authors.lastname: Pison
authors.forename: S
authors.initials: S
authors.lastname: Lantejoul
authors.forename: E
authors.initials: E
authors.lastname: Brambilla
authors.forename: C
authors.initials: C
authors.lastname: Brambilla
mesh_terms: D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000032:analysis / Q000097:blood; D008171:Lung Diseases / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D012008:Recurrence; D008258:Waldenstrom Macroglobulinemia / Q000276:immunology / Q000473:pathology*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Infiltration pulmonaire diffuse iaugurale d'une maladie de Waldenström.