[Changes in the monoamine content of the brain influence the reaction of emotional resonance].
Influence of 5-hydroxytryptophan (5HTP) and disulfiram on a reaction of emotional resonance (RER) was studied in two groups of female rats: I--with good and II--with poor elaboration of RER and, correspondingly, with the minimal and the maximal time of stay in the dark compartment. One week after 5HTP injection good elaboration of RER in animals of the I group was substituted for poor. In the II group of animals RER was unchanged. Injection of disulfiram increased the stay in the dark compartment in the I group and decreased it in the II group. At the same time dopamine content in the midbrain and medulla increased. The results confirm the hypothesis on participation of monoamines and their different contribution in RER realization in different groups of animals.
Kruglikov
R I
RI
Getsova
V M
VM
Orlova
N V
NV
Lushkina
A A
AA
Feshchenko
I R
IR
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D015306:Biogenic Monoamines / Q000032:analysis / Q000378:metabolism*; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D016009:Chi-Square Distribution; D003623:Dark Adaptation / Q000187:drug effects / Q000502:physiology; D004221:Disulfiram / Q000494:pharmacology; D004644:Emotions / Q000187:drug effects / Q000502:physiology*; D005260:Female; D051381:Rats; D017208:Rats, Wistar
D015306:Biogenic Monoamines; D006916:5-Hydroxytryptophan; D004221:Disulfiram
Izmenenie soderzhaniia monoaminov v mozge vliiaet na reaktsiiu émotsional'nogo rezonansa.