Scedosporium prolificans, a multi-resistant fungus, from a U.K. AIDS patient.
We report the first isolation of Scedosporium prolificans (inflatum) in the U.K. The patient, with advanced AIDS and neutropenia, had respiratory tract colonisation over many months without invasive disease despite neutropenia, while on itraconazole therapy. The organism was resistant in vitro to all licensed systemic antifungal agents tested.
Hopwood
V
V
Department of Microbiology, University of Leeds, U.K.
Evans
E G
EG
Matthews
J
J
Denning
D W
DW
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D003470:Culture Media; D018432:Drug Resistance, Multiple; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification*; D009181:Mycoses / Q000382:microbiology*; D012307:Risk Factors; D006113:United Kingdom
D000935:Antifungal Agents; D003470:Culture Media