title: Computer-assisted CT-guided stereotactic biopsy and brachytherapy of brain tumors.
abstract: From March 1991 to September 1993, 26 patients (aged 4-78 years) with brain tumors (4 glioblastoma multiforme, 10 nonglioblastoma multiforme, 1 mixed oligoastrocytoma, 2 carniopharyngiomas, 2 meningiomas and 7 metastases) were treated with stereotactic techniques at the Centro Internacional de Restauración Neurológica, La Habana, Cuba. A total of 28 stereotactic surgical procedures were performed with no operative mortality; they included biopsies in all cases, 1 stereotactic microsurgical resection and 12 permanent implants of 192Ir, followed by external beam fractionated radiation therapy (40-60 Gy). The present paper shows that the combined use of a stereotactic approach, a comprehensive and reliable stereotactic dosimetric planning system, stereotactic brachytherapy with 192Ir and complementary percutaneous radiation treatment constitutes a promising strategy for brain tumor management.
authors.affiliation: Centro Internacional de Restauración Neurológica, C. Habana, Cuba.
authors.forename: R
authors.initials: R
authors.lastname: Quiñones-Molina
authors.forename: A
authors.initials: A
authors.lastname: Alaminos
authors.forename: H
authors.initials: H
authors.lastname: Molina
authors.forename: J
authors.initials: J
authors.lastname: Muñoz
authors.forename: G
authors.initials: G
authors.lastname: López
authors.forename: L
authors.initials: L
authors.lastname: Alvarez
authors.forename: I
authors.initials: I
authors.lastname: Ortega
authors.forename: J
authors.initials: J
authors.lastname: Piedra
authors.forename: W
authors.initials: W
authors.lastname: Soler
authors.forename: A
authors.initials: A
authors.lastname: Torres
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods*; D001918:Brachytherapy / Q000379:methods*; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013238:Stereotaxic Techniques; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed