title: A TH1-TH2-like switch in candidiasis: new perspectives for therapy.
abstract: An imbalance in TH1-type and TH2-type responses may allow Candida albicans to modify the host response to favor its own persistence. This hypothesis has important consequences for allergy, autoimmunity and co-infection, and also highlights a potential role for cytokine and anti-cytokine therapy in Candida-related pathology.
authors.affiliation: Dept of Experimental Medicine, University of Rome Tor Vergata, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Puccetti
authors.forename: L
authors.initials: L
authors.lastname: Romani
authors.forename: F
authors.initials: F
authors.lastname: Bistoni
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000276:immunology; D002177:Candidiasis / Q000188:drug therapy / Q000276:immunology*; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000276:immunology / Q000627:therapeutic use; D006801:Humans; D007108:Immune Tolerance; D018417:Th1 Cells / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
chemical_list: D016207:Cytokines