[Long-term follow-up of a boy with recurrent hypoglycemia and cholestasis in congenital growth hormone deficiency].
We report on a four-year-old boy with congenital growth hormone deficiency who first presented at age 13 weeks with jaundice and recurrent hypoglycemia. Growth hormone deficiency was diagnosed two years later, after cholestasis and hypoglycemia had almost completely disappeared, but length deficiency became apparent. The reason for the association of cholestasis with growth hormone deficiency remains unexplained. Cholestasis can, especially in combination with hypoglycemia, be a first sign of congenital growth hormone deficiency.
Pohlenz
J
J
Universitätskinderklinik Mainz.
Wirth
S
S
Wemme
H
H
Schönberger
W
W
D001706:Biopsy; D002675:Child, Preschool; D002780:Cholestasis, Intrahepatic / Q000097:blood / Q000151:congenital*; D005500:Follow-Up Studies; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000151:congenital*; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000175:diagnosis*; D007567:Jaundice, Neonatal / Q000097:blood / Q000175:diagnosis*; D008099:Liver / Q000473:pathology; D008297:Male
D013006:Growth Hormone
Langzeitbeobachtung eines Knaben mit rezidivierenden Hypoglykämien und Cholestase bei angeborenem Wachstumshormonmangel.