title: Valvular replacement for aortic stenosis on patients in NYHA class III and IV. Early and long term results.
abstract: From January 1972 to June 1990, 112 patients between 39 and 83 years old, divided into 68 NYHA class III (60.72%) and 44 NYHA class IV, underwent surgery for aortic stenosis. There were 67 male (59.82%) and 45 female (40.18%). Early mortality included 8 patients (7.14%). Actuarial survival (including early postoperative mortality) for all 112 patients was 88.39%, 77.67%, 67.85% and 65.7% t one year, five, ten and fifteen years respectively. Clinical criteria are subjective but they remain the best prognostic factor. Surgery is indicated at occurrence of first symptoms, but, even in advanced cases, aortic valvular replacement can significantly improve survival and functional status. Even if operative risk is increased and secondary cardiomyopathy often progresses after surgery, aortic valve replacement results seem better than those of medical treatment alone.
authors.affiliation: Hôpital Cardiologique Louis Pradel, Hospices Civils de Lyon, France.
authors.forename: J F
authors.initials: JF
authors.lastname: Obadia
authors.forename: A
authors.initials: A
authors.lastname: Eker
authors.forename: G
authors.initials: G
authors.lastname: Rescigno
authors.forename: C
authors.initials: C
authors.lastname: Flamens
authors.forename: J F
authors.initials: JF
authors.lastname: Chassignolle
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve; D001024:Aortic Valve Stenosis / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome