title: Black-white differences in subclinical cardiovascular disease among older adults: the Cardiovascular Health Study. CHS Collaborative Research Group.
abstract: Cardiovascular and all-cause mortality are higher in black than white Americans, but racial differences in clinical and subclinical cardiovascular disease (CVD) have not been examined in older adults. Clinical and subclinical CVD and its risk factors were compared in 4926 white and 244 black men and women aged 65 years and older. Black participants had lower socioeconomic status and generally higher prevalences of CVD and its risk factors, except for adverse lipid profiles. Common carotid wall thickness was greater in black than white women, and ankle-arm blood pressure ratios were lower in black women and men (p < 0.01). After adjustment for CVD risk factors, common carotid walls were significantly thicker and ankle-arm ratios were lower in blacks than whites of both sexes, while internal carotid walls were significantly thinner in black women. Racial differences in clinical and subclinical CVD in older adults are similar to those reported in younger populations and do not appear to be explained by CVD risk factors.
authors.affiliation: Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA.
authors.forename: T A
authors.initials: TA
authors.lastname: Manolio
authors.forename: G L
authors.initials: GL
authors.lastname: Burke
authors.forename: B M
authors.initials: BM
authors.lastname: Psaty
authors.forename: A B
authors.initials: AB
authors.lastname: Newman
authors.forename: M
authors.initials: M
authors.lastname: Haan
authors.forename: N
authors.initials: N
authors.lastname: Powe
authors.forename: R P
authors.initials: RP
authors.lastname: Tracy
authors.forename: D H
authors.initials: DH
authors.lastname: O'Leary
mesh_terms: D000368:Aged; D044383:Black People; D002318:Cardiovascular Diseases / Q000145:classification / Q000208:ethnology*; D002339:Carotid Arteries / Q000033:anatomy & histology; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D044465:White People