title: [Selected biomarkers for evaluating occupational exposure to lead among workers from the "Miasteczko Slaskie" zincworks in Tarnowskie Gory].
abstract: A dose-response relationship between exposure to lead and delta-aminolaevulinic acid concentration in urine (ALA-U), and between blood lead (Pb-B) and zinc protoporphyrin IX (ZPP-B) concentrations in blood were examined in 90 male workers exposed to lead. Concentrations of ZPP-B correlated closely with blood lead levels. Concentrations of ALA-U ranged from 1.6 to 19.4 mg/l. These data suggest that ALA-U is a useful indicator of early effects of exposure to lead on heam biosynthesis. Lead concentrations in air at different work posts were analysed. The results obtained were compared with the levels of standard values of lead concentrations in air and with blood lead levels at those work posts.
authors.affiliation: Z Katedry i Zakładu Toksykologii, Slaskiej Akademii Medycznej, Oddział Sosnowcu.
authors.forename: J
authors.initials: J
authors.lastname: Kwapuliński
authors.forename: K
authors.initials: K
authors.lastname: Komosińska
authors.forename: D
authors.initials: D
authors.lastname: Wiechuła
authors.forename: A
authors.initials: A
authors.lastname: Kraśnicka
authors.forename: H
authors.initials: H
authors.lastname: Orczyk
mesh_terms: D000328:Adult; D000622:Aminolevulinic Acid / Q000652:urine*; D015415:Biomarkers / Q000097:blood; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D007854:Lead / Q000032:analysis*; D008297:Male; D008669:Metallurgy; D016273:Occupational Exposure / Q000032:analysis*; D011524:Protoporphyrins / Q000097:blood*; D012044:Regression Analysis; D015032:Zinc / Q000737:chemistry
chemical_list: D015415:Biomarkers; D011524:Protoporphyrins; C017803:zinc protoporphyrin; D007854:Lead; D000622:Aminolevulinic Acid; D015032:Zinc
vernacular_title: Wybrane biomarkery oceny ekspozycji zawodowej na ołów pracowników Huty Cynku "Miasteczko Slaskie" w Tarnowskich Górach.