title: [Imprints of coronary plaque particles in the PTCA balloon surface during the dilatation processing].
abstract: Seventy-six PTCA-balloons after coronary angioplasty were studied for superficial changes using scanning electron microscopy (SEM) after fixing in glutardialdehyde. Coronary plaque particles were identified on the balloon surface in 52 cases (68%). Twelve new and unused balloons were subjected to the same chemical treatment and SEM showed no imprints. The average length of the longest imprinted plaques was 128 +/- 201 microns and the average number of plaque particles per balloon was 4.9 +/- 2.7. The maximal dilatation pressure and the number of dilatations showed no influence on the impregnation of plaque particles. However, longer plaque imprints tended to occur under low dilatation pressure. Imprints of plaque particles were significantly higher in patients with low cholesterol (p = 0.0001) and low triglycerides (p = 0.0016). No correlation was seen between imprint length and lipid levels. Similarly, the different balloon materials (polyethylene, polyolefincopolymer) showed no significant differences with regard to plaque occurrence. The PTCA-balloons, plaque particles and six coronary plaques obtained after endatherectomy were subjected to energy dispersive x-ray analysis (EDX) under SEM as EDX reveals qualitative and quantitative information about the structural elements. Highly significant differences in calcium, sodium, phosphorus and silicon contents (p = 0.0000) between plaque particles and balloon surface were observed, owing to the absence of these in balloon material. Thus EDX offers additional advantages over SEM in that it clearly differentiates deformed balloon surface, plaque particle, and retained contrast medium.
  
  
  CONCLUSIONS
  Plaque particles can be recovered from balloon surfaces after PTCA. Depending upon their size, they could lead to coronary spasm or microembolic phenomenon.
authors.affiliation: Klinik und Poliklinik für Innere Medizin Abteilung für Kardiologie Universität Rostock.
authors.forename: D
authors.initials: D
authors.lastname: Werner
authors.forename: D
authors.initials: D
authors.lastname: Behrend
authors.forename: K P
authors.initials: KP
authors.lastname: Schmitz
authors.forename: W
authors.initials: W
authors.lastname: Urbaszek
mesh_terms: D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D002784:Cholesterol / Q000097:blood; D003324:Coronary Artery Disease / Q000473:pathology* / Q000628:therapy; D004577:Electron Probe Microanalysis; D004730:Endothelium, Vascular / Q000473:pathology; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010316:Particle Size; D013499:Surface Properties; D014280:Triglycerides / Q000097:blood
chemical_list: D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Impression koronarer Plaquepartikel in die PTCA-Ballonoberfläche durch den Dilatationsprozess.