title: [Interstitial lung diseases--the clinical aspects of the problem].
abstract: Upon analysis of 550 cases of different chronic diffuse pulmonary diseases included in a group of interstitial diseases of the lungs (IDL) the authors came to the conclusion that IDL incorporate such variants as alveolitis, pulmonary vasculitis and pulmonary hemorrhages; granulomatosis covers exogenic allergic alveolitis, alveolitis in chronic active hepatitis; vasculitis group includes such rare diseases as necrotizing sarcoid granulomatosis vasculitis and lymphoid granulomatosis; fibrosing alveolitis--secondary alveolitis in sclerodermia systematica, rheumatoid arthritis, Sjogren's disease, chronic active hepatitis. Knowledge of IDL etiology (environmental, occupational, induced by radionuclides, drugs, viruses, fungi) with focus on drug affection of the lungs is thought of value. Biopsy and bronchial lavage findings are compared clinically and morphologically. Mechanisms of pulmonary fibrosis and approaches to inhibition of pulmonary fibrosis progression are outlined.
authors.forename: N A
authors.initials: NA
authors.lastname: Mukhin
authors.forename: V V
authors.initials: VV
authors.lastname: Serov
authors.forename: B M
authors.initials: BM
authors.lastname: Kornev
authors.forename: E A
authors.initials: EA
authors.lastname: Kogan
authors.forename: A S
authors.initials: AS
authors.lastname: Drozdova
authors.forename: R A
authors.initials: RA
authors.lastname: Shukurova
authors.forename: E N
authors.initials: EN
authors.lastname: Semenkova
authors.forename: T N
authors.initials: TN
authors.lastname: Lopatkina
authors.forename: A A
authors.initials: AA
authors.lastname: Ovchinnikov
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D008297:Male
vernacular_title: Interstitsial'nye bolezni legkogo--klinicheskie aspekty problemy.