title: [Hepatocarcinoma: analysis of 14 cases].
abstract: In Brazil, hepatocellular carcinoma (HCC) is not a common tumour. Virus B hepatitis and cirrhosis play an important role in the development of HCC. The authors described 14 cases of HCC registered in our service during the last 33 months. PURPOSE--Evaluate clinical and laboratory aspects of the hepatocarcinoma treated in our service. MATERIAL--Fourteen patients evaluated between 1990 and 1993 were described. Ten were men the median age was 53 years. RESULTS--The main symptoms were: abdominal pain, weight loss and jaundice. Among the fourteen patients, 42% percent were positive for HBsAg, 0.7% for anti HCV and 57% were cirrhotic. Eighty percent had an advanced disease and serum alphafeto-protein was elevated in 92%. The patients underwent different kinds of treatment. Systemic chemotherapy was started in 5 patients, however without any response. Surgery was done in three patients, one underwent partial resection of the tumour and in the others a total resection was carried out. CONCLUSION--The hepatocarcinoma is rare in our service, eighty percent had advanced disease and 42% were positive for HBsAg.
authors.affiliation: Disciplina de Gastroenterologia Clínica da Escola Paulista de Medicina, São Paulo.
authors.forename: N M
authors.initials: NM
authors.lastname: Forones
authors.forename: L A
authors.initials: LA
authors.lastname: Queiroz
authors.forename: V F
authors.initials: VF
authors.lastname: Blum
authors.forename: E R
authors.initials: ER
authors.lastname: Parise
authors.forename: J
authors.initials: J
authors.lastname: Szeynfeld
authors.forename: T
authors.initials: T
authors.lastname: Trivino
authors.forename: V P
authors.initials: VP
authors.lastname: Barbosa
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
vernacular_title: Hepatocarcinoma: análise de 14 casos.