title: Kallmann syndrome and delayed puberty associated with agenesis of lateral maxillary incisors.
abstract: In six adolescents, we documented the association of either Kallmann syndrome or delayed puberty with agenesis of the lateral maxillary incisors. As the neurons secreting gonadotropin-releasing hormone originate from the olfactory placode, this newly recognized association appears to be the clinical expression of a developmental field defect.
authors.affiliation: Department of Pediatrics, University of Leuven, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: de Zegher
authors.forename: L
authors.initials: L
authors.lastname: Lagae
authors.forename: D
authors.initials: D
authors.lastname: Declerck
authors.forename: F
authors.initials: F
authors.lastname: Vinckier
mesh_terms: D000293:Adolescent; D000848:Anodontia / Q000150:complications*; D005260:Female; D006801:Humans; D007180:Incisor / Q000002:abnormalities*; D017436:Kallmann Syndrome / Q000150:complications*; D008297:Male; D008437:Maxilla; D009833:Olfactory Pathways / Q000196:embryology; D011628:Puberty, Delayed / Q000150:complications*