title: Thrombolysis in acute myocardial infarction following prolonged cardiopulmonary resuscitation.
abstract: Thrombolytic therapy was administered to a 64-year-old man with an acute anterolateral myocardial infarction who had received cardiopulmonary resuscitation (CPR) for 24 minutes. At the time of thrombolytic therapy, the patient was alert and without clinical or radiographic evidence of injury. The patient developed a retroperitoneal hematoma related to femoral line placement, as well as subcutaneous bruising of the anterior chest wall; both were self-limited. No long- term morbidity developed, and the myocardial infarction was aborted. The use of thrombolytic therapy for patients with acute myocardial infarction who have received CPR is reviewed. In the absence of clinical or radiographic evidence of trauma from CPR, patients with acute myocardial infarction should not be excluded from receiving thrombolytic therapy solely because of having had CPR or the duration of CPR.
authors.affiliation: Oregon Health Sciences University, Department of Emergency Medicine, Portland 97201, USA.
authors.forename: C S
authors.initials: CS
authors.lastname: Merriman
authors.forename: N D
authors.initials: ND
authors.lastname: Kalbfleisch
mesh_terms: D016887:Cardiopulmonary Resuscitation; D000075202:Contraindications; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D013997:Time Factors