title: Ion-channel gating. Twist to open.
abstract: Three-dimensional images of the open state of the nicotinic acetylcholine receptor have been obtained at 9 A resolution. Comparison with the closed state reveals the structural basis of channel gating.
authors.affiliation: Laboratory of Molecular Biophysics, University of Oxford, UK.
authors.forename: M S
authors.initials: MS
authors.lastname: Sansom
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000595:Amino Acid Sequence; D015640:Ion Channel Gating / Q000502:physiology*; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011978:Receptors, Nicotinic / Q000737:chemistry* / Q000502:physiology*
chemical_list: D011978:Receptors, Nicotinic; D000109:Acetylcholine