Evaluation of the Technicon Immuno I random access immunoassay analyzer and calculation of pediatric reference ranges for endocrine tests, T-uptake, and ferritin.
OBJECTIVE
Evaluation of the precision, accuracy, and user-friendliness of the Technician Immuno I. Calculation of pediatric reference ranges for ferritin and endocrine tests run on Immuno I.


METHODS
Precision and accuracy were measured using controls and method comparison studies. Pediatric reference ranges were calculated by comparing the Immuno I results for 100 patients with those of the Abbott IMx and TDx. The regression equation obtained was then used to convert the IMx and TDx reference ranges to reference ranges for the Immuno I.


RESULTS
The Immuno I provided both accurate and precise measurement of drugs and endocrine hormones. Pediatric reference ranges were obtained for ferritin and all endocrine tests.


CONCLUSIONS
The Immuno I is user-friendly and provides reliable measurement of both the drugs tested and endocrine tests on a micro-sample. Reagent and curve stability are excellent.
Murthy
J N
JN
Department of Laboratory Medicine, Children's National Medical Center, Washington, DC 20010, USA.
Hicks
J M
JM
Soldin
S J
SJ
D000293:Adolescent; D000328:Adult; D001322:Autoanalysis; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D005293:Ferritins / Q000097:blood*; D006728:Hormones / Q000097:blood*; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012015:Reference Standards; D015203:Reproducibility of Results; D013974:Thyroxine / Q000097:blood*; D014584:User-Computer Interface
D006728:Hormones; D005293:Ferritins; D013974:Thyroxine