title: Analysis of beta-thalassemia mutations in the United Arab Emirates provides evidence for recurrent origin of the IVSI nt 5 (G-C) mutation.
abstract: Beta-thalassemia mutations were characterized in a sample of 70 patients from United Arab Emirates (U.A.E.), resulting in an enlargement of the spectrum of types found in the country. The complete association between the most common IVS I nt 5 (G-C) mutation and a specific haplotype reveals an independent origin of this mutation in U.A.E.
authors.affiliation: Institute of Cell Biology, C.N.R., Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: De Leo
authors.forename: G
authors.initials: G
authors.lastname: Deidda
authors.forename: A
authors.initials: A
authors.lastname: Novelletto
authors.forename: S
authors.initials: S
authors.lastname: el-Kalla
authors.forename: A R
authors.initials: AR
authors.lastname: Mathews
authors.forename: L
authors.initials: L
authors.lastname: Felicetti
mesh_terms: D004252:DNA Mutational Analysis; D006239:Haplotypes; D006801:Humans; D009154:Mutation; D012008:Recurrence; D014479:United Arab Emirates; D017086:beta-Thalassemia / Q000235:genetics*