title: [Experimental study on anti-duck hepatitis B viral effect of Phyllanthus urinaria of different areas and combined therapy with other drugs].
abstract: The duck hepatitis B virus model was treated with phyllanthus urinaria of different area and combined with Sophora flavesceus as well as ciprofloxacin once a day for one month, the results indicated: Guangxi and Yunnan Phyllanthus could lower the serum DHBV DNA significantly (P < 0.05), but Chongqing Phyllanthus couldn't. And the amount of serum DHBV DNA rose a week after stopping of Yunnan Phyllanthus. The antiviral effect of Guangxi Phyllanthus combined with ciprofloxacin seems to be strengthened (P < 0.05).
authors.affiliation: Institute for Viral Hepatitis, Chongqing University of Medical Sciences, Sichuan.
authors.forename: Y X
authors.initials: YX
authors.lastname: Chen
authors.forename: S H
authors.initials: SH
authors.lastname: Guo
authors.forename: D F
authors.initials: DF
authors.lastname: Zhang
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004279:DNA, Viral / Q000097:blood; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004372:Ducks; D018347:Hepadnaviridae Infections / Q000188:drug therapy*; D015611:Hepatitis B Virus, Duck / Q000187:drug effects* / Q000235:genetics; D011201:Poultry Diseases / Q000188:drug therapy*; D013045:Species Specificity
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D004365:Drugs, Chinese Herbal; D002939:Ciprofloxacin