title: A clinicopathological and immunohistochemical analysis of primary oral mucosal melanoma.
abstract: Nine cases of primary oral mucosal melanoma in Caucasian patients were reviewed and the tumours analysed for expression of S100, HMB45, NKI/C3, HLA-DR, PCNA, cytokeratin and von Willebrand factor. The clinical, histopathological and immunohistochemical features were quite distinctive and our findings support previous suggestions that oral melanoma should be classified as a separate entity rather than as a sub-type of cutaneous melanoma.
authors.affiliation: Joint Department of Oral Pathology, Eastman Dental Institute, London, UK.
authors.forename: A W
authors.initials: AW
authors.lastname: Barrett
authors.forename: J H
authors.initials: JH
authors.lastname: Bennett
authors.forename: P M
authors.initials: PM
authors.lastname: Speight
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000032:analysis; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008543:Melanins / Q000032:analysis; D008545:Melanoma / Q000378:metabolism / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000378:metabolism / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis
chemical_list: D000951:Antigens, Neoplasm; D006684:HLA-DR Antigens; D008543:Melanins; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D018809:Proliferating Cell Nuclear Antigen; D009418:S100 Proteins