title: The estimation of inspired isoflurane concentration in a low-flow system.
abstract: We have examined the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system. Twenty one adult patients requiring mechanical ventilation of the lungs during surgery took part in this study. Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia. The ratio was maintained throughout the procedure, except for a few minutes following each change in vaporizer setting.
authors.affiliation: Department of Anaesthesia, Hammersmith Hospital, London.
authors.forename: S
authors.initials: S
authors.lastname: Gowrie-Mohan
authors.forename: M K
authors.initials: MK
authors.lastname: Chakrabarti
authors.forename: G G
authors.initials: GG
authors.lastname: Lockwood
mesh_terms: D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D013997:Time Factors
chemical_list: D007530:Isoflurane