title: Frontometaphyseal dysplasia: neonatal radiographic diagnosis.
abstract: Frontometaphyseal dysplasia (FMD) is an uncommon genetic syndrome affecting bone and connective tissue. This condition is characterized by hyperostosis of the skull and prominence of the supraorbital ridges; long bones have flared metaphyses. Frontometaphyseal dysplasia is an X-linked dominant trait with more severe manifestations in males and with extreme variability in females. Diagnosis in the neonatal period is difficult. We present 2 newborn boys with the radiographic findings of FMD.
authors.affiliation: Department of Diagnostic Imaging and Radiology, Children's National Medical Center, Washington, District of Columbia, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Glass
authors.forename: K N
authors.initials: KN
authors.lastname: Rosenbaum
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D000328:Adult; D002675:Child, Preschool; D003238:Connective Tissue / Q000002:abnormalities / Q000000981:diagnostic imaging; D005147:Facial Bones / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011859:Radiography; D012886:Skull / Q000002:abnormalities* / Q000000981:diagnostic imaging