title: Dialysis-related amyloidosis manifested as masses in the buttocks.
abstract: A 40-year-old man had enlarging painful gluteal masses that developed after 17 years of hemodialysis. Pathologic examination revealed extensive deposition of beta 2-microglobulin amyloid. A bladder biopsy done during evaluation for possible transplantation also showed amyloid deposits. This constellation of findings has not been reported in a patient with beta 2-microglobulin amyloidosis. Patients with dialysis-related amyloidosis should be carefully assessed for systemic involvement. Renal transplantation may prevent further amyloid deposition and provide relief of pain.
authors.affiliation: Department of Nephrology, Maimonides Medical Center, Brooklyn, NY 11219, USA.
authors.forename: H I
authors.initials: HI
authors.lastname: Lipner
authors.forename: S
authors.initials: S
authors.lastname: Minkowitz
authors.forename: G
authors.initials: G
authors.lastname: Neiderman
authors.forename: B M
authors.initials: BM
authors.lastname: Louis
authors.forename: B S
authors.initials: BS
authors.lastname: Hoch
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000209:etiology* / Q000378:metabolism; D002081:Buttocks; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects*; D001743:Urinary Bladder / Q000378:metabolism; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D001613:beta 2-Microglobulin