Two possible mechanisms for survival and initiation of Murray Valley encephalitis virus activity in the Kimberley region of Western Australia.
Two possible mechanisms are described for the initiation of Murray Valley encephalitis (MVE) virus activity in arid, epizootic regions of tropical Australia. Virus isolations were made from mosquitoes trapped shortly after the first heavy wet season rains and flooding in the east Kimberley, which followed approximately nine months of drought. A number of isolates of MVE virus were obtained, including isolates from pools of blood-engorged Culex annulirostris mosquitoes and from a single pool of male Aedes tremulus mosquitoes. The results strongly suggested that MVE virus activity was due both to its introduction in viremic vertebrate hosts, from which first-generation mosquitoes became infected following blood meals, and also to reactivation of vertically transmitted virus from desiccation-resistant eggs of Ae. tremulus. Both mechanisms are discussed with respect to environmental conditions.
Broom
A K
AK
Department of Microbiology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands.
Lindsay
M D
MD
Johansen
C A
CA
Wright
A E
AE
Mackenzie
J S
JS
D000330:Aedes / Q000821:virology*; D000818:Animals; D003465:Culex / Q000821:virology*; D018068:Encephalitis Virus, Murray Valley / Q000302:isolation & purification / Q000502:physiology*; D004671:Encephalitis, Arbovirus / Q000453:epidemiology / Q000635:transmission; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D007303:Insect Vectors / Q000821:virology*; D008297:Male; D011891:Rain; D014775:Virus Activation / Q000502:physiology*; D014776:Virus Cultivation; D014904:Western Australia / Q000453:epidemiology