title: Wound infection after abdominal hysterectomy: effect of the depth of subcutaneous tissue.
abstract: OBJECTIVE
  Our purpose was to determine the effect of the depth of the subcutaneous tissue at the operative site on abdominal wound infection after hysterectomy.
  
  
  METHODS
  A prospective study was performed of women undergoing abdominal hysterectomy and not receiving antibiotic prophylaxis who underwent maximum vertical measurement of their subcutaneous incisions before the abdominal cavity was surgically entered. Additional demographic and perioperative data previously associated with wound infection were collected and analyzed. Surgical technique was standardized among the three attending surgeons involved.
  
  
  RESULTS
  Wound infection occurred in 17 of 150 (11.3%) women undergoing abdominal hysterectomy. Univariate analysis identified the following risk factors as being significantly associated with wound infection: depth of subcutaneous tissue (p = 0.0004), preoperative serum albumin (0.0015), weight (p = 0.0029), and body mass index (p = 0.0032). Logistic regression analysis confirmed the thickness of the subcutaneous tissue as the only significant risk factor for wound infection (p = 0.04) (odds ratio 1.37, 95% confidence interval 1.01 to 1.86). No patients with a maximum depth of subcutaneous tissue < 3 cm had a wound infection.
  
  
  CONCLUSIONS
  We conclude that the depth of subcutaneous tissue is the most significant risk factor associated with abdominal wound infection after hysterectomy.
authors.affiliation: Department of Obstetrics and Gynecology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0034, USA.
authors.forename: D E
authors.initials: DE
authors.lastname: Soper
authors.forename: R C
authors.initials: RC
authors.lastname: Bump
authors.forename: W G
authors.initials: WG
authors.lastname: Hurt
mesh_terms: D000005:Abdomen; D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D015992:Body Mass Index; D001835:Body Weight; D003238:Connective Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis; D012867:Skin / Q000473:pathology; D013530:Surgical Wound Infection / Q000209:etiology* / Q000473:pathology
chemical_list: D012709:Serum Albumin