title: Bone mineral density changes in distracted callus stimulated by pulsed direct electrical current.
abstract: To evaluate the effect of application of pulsed direct current electrical stimulation to callus tissue, a 1-cm bone-lengthening model using an external lengthener was applied to rabbit tibia. Twenty-microampere pulsed direct current was applied 12 hours daily from the day of osteotomy until 40 days after the completion of lengthening. The area, bone mineral content, and bone mineral density of the distracted callus and of the proximal and distal segments of the tibia were evaluated using dual-energy xray absorptiometry. The absolute and relative values of bone mineral density of the electrically stimulated callus were significantly increased as compared with those in the control group. Pulsed direct current electrical stimulation may be indicated in bone lengthening to stimulate the poorly mineralized callus, and may shorten the overall time course of leg lengthening.
authors.affiliation: Department of Orthopaedic Surgery, Kinki University School of Medicine, Osaka, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Hamanishi
authors.forename: T
authors.initials: T
authors.lastname: Kawabata
authors.forename: T
authors.initials: T
authors.lastname: Yoshii
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D015502:Absorptiometry, Photon; D000818:Animals; D015519:Bone Density; D001852:Bone Lengthening; D002146:Bony Callus / Q000502:physiology*; D004599:Electric Stimulation Therapy; D008297:Male; D011817:Rabbits