title: Tc-99m phytate bone marrow scintigraphy showing multiple areas of focal hyperactivity in a patient with lung cancer. A case report.
abstract: Focal hyperactivity indicative of metastases is a rare finding in bone marrow imaging. In a lung cancer patient with multiple bony metastases, the Tc-99m phytate bone marrow imaging revealed multiple focal areas of increased radioactivity corresponding to the bone scan findings. The findings presented are consistent with a previous animal study, which found that phytate distribution was similar to that of diphosphonate in the skeletal system of rats and rabbits. The authors conclude that Tc-99m phytate should not be used as a bone marrow imaging agent. Further studies of Tc-99m phytate bone marrow scintigraphy on human beings are under way.
authors.affiliation: Department of Nuclear Medicine, Taipei Veterans General Hospital, Taiwan.
authors.forename: C P
authors.initials: CP
authors.lastname: Chang
authors.forename: L S
authors.initials: LS
authors.lastname: Chu
authors.forename: R S
authors.initials: RS
authors.lastname: Liu
authors.forename: S M
authors.initials: SM
authors.lastname: Yu
authors.forename: S H
authors.initials: SH
authors.lastname: Yeh
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000556:secondary; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging
chemical_list: D015609:Organotechnetium Compounds; C026177:technetium phytate; D010833:Phytic Acid