title: Metabolism of the Fusarium mycotoxins zearalenone and deoxynivalenol by yeast strains of technological relevance.
abstract: The Fusarium mycotoxin zearalenone (ZEA), added at a level of 2 micrograms/ml, was reduced stereoselectively by cultures of Candida tropicalis, Torulaspora delbrückii, Zygosaccharomyces rouxii, and 7 Saccharomyces strains to both alpha- and beta-zearalenol. In contrast, only alpha-zearalenol was produced from ZEA by Pichia fermentans and several yeast strains of the genera Candida, Hansenula, Brettanomyces, Schizosaccharomyces, and Saccharomycopsis. No glucose conjugates of ZEA (zearalenone-4-beta-D-glucopyranoside) were detected. The trichothecene mycotoxin deoxynivalenol (DON) was not metabolized by any of the yeast strains that were used for analysis.
authors.affiliation: Bayerische Landesanstalt für Ernährung, Abteilung Ernährung, München, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Böswald
authors.forename: G
authors.initials: G
authors.lastname: Engelhardt
authors.forename: H
authors.initials: H
authors.lastname: Vogel
authors.forename: P R
authors.initials: PR
authors.lastname: Wallnöfer
mesh_terms: D001515:Beer / Q000382:microbiology; D001711:Biotransformation; D013045:Species Specificity; D013997:Time Factors; D014255:Trichothecenes / Q000493:pharmacokinetics*; D014920:Wine / Q000382:microbiology; D015003:Yeasts / Q000254:growth & development / Q000378:metabolism*; D015025:Zearalenone / Q000493:pharmacokinetics*
chemical_list: D014255:Trichothecenes; D015025:Zearalenone; C007262:deoxynivalenol