[Acute renal failure associated with 5-aminosalicylic acid in inflammatory bowel disease].
A case of acute renal failure with characteristics of interstitial nephritis associated to treatment with mesalazine (5-ASA bound to resin) in a 26-year old patient with a 7-year history of Crohn's disease is presented. The patient had been previously treated with 5-ASA with no alterations in renal function being observed. Renal failure became manifest several days after initiation of maintenance therapy with 5-ASA during the latest outbreak of intestinal inflammatory disease and disappeared upon suppression of the drug.
García-Díaz
M
M
Unidad de Aparato Digestivo, Hospital Regional Universitario Infanta Cristina, Universidad de Extremadura, Badajoz.
Nevado
L
L
Berenguer
A
A
Bureo
J C
JC
Bureo
P
P
Sáenz de Santamaría
J
J
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000328:Adult; D000636:Aminosalicylic Acids / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D019804:Mesalamine
D000636:Aminosalicylic Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine
Insuficiencia renal aguda asociada a ácido 5-aminosalicílico en la enfermedad inflamatoria intestinal.