title: Unconstrained bacterial promiscuity: the Tn916-Tn1545 family of conjugative transposons.
abstract: Conjugative transposons are highly ubiquitous elements found throughout the bacterial world. Members of the Tn916-Tn1545 family carry the widely disseminated tetracycline-resistance determinant Tet M, as well as additional resistance genes. They have been found naturally in, or been introduced into, over 50 different species and 24 genera of bacteria. Recent investigations have led to insights into the molecular basis of movement of these interesting mobile elements.
authors.affiliation: Dept of Biologic and Materials Sciences, School of Dentistry, School of Medicine, University of Michigan, Ann Arbor 48109, USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Clewell
authors.forename: S E
authors.initials: SE
authors.lastname: Flannagan
authors.forename: D D
authors.initials: DD
authors.lastname: Jaworski
mesh_terms: D001419:Bacteria / Q000235:genetics*; D003227:Conjugation, Genetic / Q000235:genetics*; D004251:DNA Transposable Elements / Q000235:genetics*; D010957:Plasmids / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements