The MUC5AC gene: RFLP analysis with the Jer58 probe.
We have recently obtained evidence that the locus corresponding to three groups of partial tracheobronchial cDNAs (A = Jer47, B = Jer57, C = Jer58) which mapped to chromosome 11p15 and was given the symbol MUC5 corresponds to two distinct genes which we have provisionally called MUC5B and MUC5AC. Here we describe the detection, using the Jer58 probe, which contains a 24-bp tandem repeat, of polymorphism in the MUC5AC gene with seven different restriction enzymes.
Pigny
P
P
U377 INSERM, Lille, France.
Pratt
W S
WS
Laine
A
A
Leclercq
A
A
Swallow
D M
DM
Nguyen
V C
VC
Aubert
J P
JP
Porchet
N
N
D001980:Bronchi / Q000737:chemistry*; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D015342:DNA Probes; D018076:DNA, Complementary / Q000235:genetics; D005799:Genes, Dominant; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid; D014132:Trachea / Q000737:chemistry*
D015342:DNA Probes; D018076:DNA, Complementary