Dialysis-related amyloidosis manifested as masses in the buttocks.
A 40-year-old man had enlarging painful gluteal masses that developed after 17 years of hemodialysis. Pathologic examination revealed extensive deposition of beta 2-microglobulin amyloid. A bladder biopsy done during evaluation for possible transplantation also showed amyloid deposits. This constellation of findings has not been reported in a patient with beta 2-microglobulin amyloidosis. Patients with dialysis-related amyloidosis should be carefully assessed for systemic involvement. Renal transplantation may prevent further amyloid deposition and provide relief of pain.
Lipner
H I
HI
Department of Nephrology, Maimonides Medical Center, Brooklyn, NY 11219, USA.
Minkowitz
S
S
Neiderman
G
G
Louis
B M
BM
Hoch
B S
BS
D000328:Adult; D000686:Amyloidosis / Q000209:etiology* / Q000378:metabolism; D002081:Buttocks; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects*; D001743:Urinary Bladder / Q000378:metabolism; D001613:beta 2-Microglobulin / Q000378:metabolism
D001613:beta 2-Microglobulin