[Does the basic therapy affect the development of secondary amyloidosis in rheumatoid arthritis?].
Anti-rheumatic drug treatments were studied in 260 patients from Finland and Russia suffering from rheumatoid arthritis (RA) with or without biopsy-proven secondary amyloidosis (RSA). Chloroquine was used for longer period in RSA group in Russia (p = 0.003) and in Finland (p = 0.06). In Finland chloroquine was used more often in the RSA group (p = 0.02), and sulphasalazine (p = 0.02), D-penicillamine (p = 0.03) and cytotoxics (p = 0.04) in the control group. The role of therapy in the prevention of RSA in chronic inflammation is discussed.
Prokaeva
T B
TB
Alekberova
Z S
ZS
Radenska-Lopovok
S G
SG
Tiitinen
S
S
Kaarela
K
K
Kautiainen
H
H
D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016009:Chi-Square Distribution; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D012426:Russia; D018709:Statistics, Nonparametric; D013997:Time Factors
D018501:Antirheumatic Agents
Vliiaet li terapiia bazisnogo riada na razvitie vtorichnogo amiloidoza pri revmatoidnom artrite?