title: Clinical and radiographical split-mouth-study on resorbable versus non-resorbable GTR-membranes.
abstract: The aim of this prospective split-mouth-study was to compare the 5-months-healing results after implantation of resorbable (Polyglactin-910) and non-resorbable (e-PTFE) GTR-membranes. 12 healthy patients with 41 periodontal defects were treated. Radiographical and clinical examinations (papillary bleeding index, gingival recession, probing pocket depth, probing attachment level, and furcation depth) were carried out under standardized conditions immediately before and 5 months after surgery. The vertical relative attachment gain (V-rAG) was calculated as a % of the bony defect depth (intra-operatively measured) at baseline, and the horizontal relative attachment gain (H-rAG) as a % of the furcation depth at baseline. The standardized radiographs were evaluated blind by 4 experienced examiners for changes of the alveolar bone. Furthermore, digital subtraction radiography was carried out using the standard deviation of the grey level histograms in the experimental region and in a control region as a test parameter for bone changes. Both types of membranes achieved an attachment gain. Using the split-mouth-design, no statistically significant (< or = 0.05) difference between the two membranes could be detected (number of defects/median) with regard to V-rAG (Polyglactin: 12/77.5%, e-PTFE: 12/73.2%) or to H-rAG of class-II-furcations (Polyglactin: 5/66.7%, e-PTFE: 5/66.7%), or to bone changes using conventional and subtraction radiographic evaluation. In conclusion based on this 5-months-study, the resorbable membranes provided attachment gain comparable to the e-PTFE-membranes.
authors.affiliation: Department of Operative Dentistry and Peridontology, University of Regensburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Christgau
authors.forename: G
authors.initials: G
authors.lastname: Schmalz
authors.forename: E
authors.initials: E
authors.lastname: Reich
authors.forename: A
authors.initials: A
authors.lastname: Wenzel
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001673:Biodegradation, Environmental; D005260:Female; D017823:Furcation Defects / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005884:Gingival Hemorrhage / Q000473:pathology; D005889:Gingival Recession / Q000473:pathology / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000473:pathology / Q000601:surgery; D010510:Periodontal Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000473:pathology / Q000601:surgery; D011098:Polyglactin 910 / Q000737:chemistry; D011138:Polytetrafluoroethylene / Q000737:chemistry; D011446:Prospective Studies; D011856:Radiographic Image Enhancement; D013382:Subtraction Technique; D014945:Wound Healing
chemical_list: D008567:Membranes, Artificial; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene