[Clinico-genealogical and genetic-mathematical research on cancer of the cervix uteri].
Analysis of the family histories of 179 patients with cancer of uterine cervix was conducted to detect the influence of their heredity and environmental factors on the development of malignant tumors using clinical-genealogical and genetic-mathematical methods. Decomposition of phenotypic variance was used as a basis for detecting the contribution of genetic component (2.92%) and random environmental component (97.08%) which reflected the influence of exogenic risk factors of development of uterine cervix cancer. Clinico-genealogical analysis of probands' pedigrees was the basis for detecting association of malignant neoplasms in lung and uterine cervix epithelia.
Isakova
L M
LM
Hanina
K P
KP
Osins'ka
O V
OV
Vinnyts'ka
A B
AB
D000328:Adult; D000483:Alleles; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D005821:Genetic Techniques; D006801:Humans; D010375:Pedigree; D010641:Phenotype; D011795:Surveys and Questionnaires; D014455:Ukraine; D002583:Uterine Cervical Neoplasms / Q000209:etiology / Q000235:genetics*
Kliniko-henealohichne ta henetyko-matematychne doslidzhennia raku shyĭky matky.