Production of monoclonal antibody against hepatitis B surface antigen.
HBV infection is a major health problem in Southeast Asia. Thailand is considered to be an endemic area of HBV infection(18). Prevalence of HBsAg carriers is 5.2 per cent in children, 9 per cent in adults and 5.6 per cent in pregnant women(19,20). We believe that the monoclonal antibody described in the present report will be useful to develop HBsAg-KIT for national serologic screening assay, as considered in terms of sensitivity, specificity and cost effectiveness.
Tangkananond
W
W
Institute of Pre-Clinical Sciences, Faculty of Medicine, Thammasat University, Pratumthani, Thailand.
Charoensiriwatana
W
W
Vanichanon
A
A
Janejai
N
N
Wetprasit
N
N
Shewsuwan
P
P
Pojanagaroon
B
B
Saguanwonge
S
S
Bhumisawasdi
J
J
Jayavasu
C
C
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006509:Hepatitis B / Q000175:diagnosis* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D012680:Sensitivity and Specificity; D012698:Serologic Tests
D000911:Antibodies, Monoclonal; D006514:Hepatitis B Surface Antigens