title: Cogan's syndrome mimicking acute Lyme arthritis.
abstract: A pediatric case of Cogan's syndrome mimicking acute Lyme arthritis is described. A 12-year-old black boy was admitted to the pediatric service for presumed right knee septic arthritis. Symptoms included acute pain and swelling with decreased range-of-motion. Although the patient's right knee symptoms and positive Lyme serology were consistent with a diagnosis of Lyme arthritis, the presence of sensorineural hearing loss and interstitial keratitis with inflammatory arthritis suggested a diagnosis of Cogan's syndrome. Subsequent Western blot analysis was negative for Borrelia burgdorferi antigens. The patient had dramatic clinical improvement of musculoskeletal and ophthalmologic complaints shortly after receiving high-dose corticosteroids, although residual sensorineural hearing loss persisted.
authors.affiliation: Orthopaedic Surgery Service, Grandview Hospital, Dayton, Ohio, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Schwegmann
authors.forename: R J
authors.initials: RJ
authors.lastname: Enzenauer
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007634:Keratitis / Q000150:complications / Q000175:diagnosis*; D008193:Lyme Disease / Q000175:diagnosis*; D008297:Male; D013577:Syndrome