[Adherence to HEp-2 cells of enterotoxemic Escherichia coli O-group 139 from pigs with edema disease].
One hundred and one strains of enterotoxemic Escherichia coli (ETEEC) O-group 139 isolated from swine with edema disease were investigated for their adherence to HEp-2 cells in the presence of D-mannose. All strains adhered in large numbers to the cells (21 to 60 bacteria/cell). No correlation was found between the presence of F107 fimbria on the organisms and the adherence to the cells. Adhesion-inhibition tests showed that anti-K12 serum inhibited the adhesion ETEEC O-group 139 (an inhibition rate of 63 to 65%), but anti-F107 or anti-O139 sera did not. These results indicate that the capsular K12 antigen may be one of the pathogenic factors of ETEEC O-group 139.
Nakazawa
M
M
Kyushu Branch Laboratory, National Institute of Animal Health, Kagoshima, Japan.
Kataoka
Y
Y
Ohya
T
T
D000818:Animals; D001422:Bacterial Adhesion; D016667:Bacterial Capsules; D004488:Edema Disease of Swine / Q000382:microbiology*; D004926:Escherichia coli / Q000145:classification / Q000472:pathogenicity*; D006801:Humans; D011135:Polysaccharides, Bacterial / Q000502:physiology; D012703:Serotyping; D013552:Swine; D014407:Tumor Cells, Cultured
D011135:Polysaccharides, Bacterial; C050671:capsular polysaccharide K12