title: Histiocytosis X of the vulva with a confusing clinical and pathologic presentation. A case report.
abstract: Histiocytosis X (HX) is a rare disorder of Langerhans cells and most commonly occurs in children. We report a case of HX of the vulva in a 76-year-old woman that clinically simulated a yeast infection of the vulva but histologically resembled an amelanotic melanoma. We briefly report the clinical and pathologic features of this case, which responded to vincristine followed by vinblastine and was in complete remission after nine months.
authors.affiliation: Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City 52242-1009, USA.
authors.forename: V
authors.initials: V
authors.lastname: Savell
authors.forename: R
authors.initials: R
authors.lastname: Hanna
authors.forename: J A
authors.initials: JA
authors.lastname: Benda
authors.forename: Z B
authors.initials: ZB
authors.lastname: Argenyi
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D018328:Melanoma, Amelanotic / Q000473:pathology*; D009181:Mycoses / Q000473:pathology*; D014845:Vulvar Diseases / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology*