Partial orthotopic liver transplantation in rats.
A partial orthotopic liver transplantation technique (70% POLT) for use in rats and comparable with the corresponding recipient operation in the 'splitting transplantation' in man was developed. Body weight, liver function, histological and electron-microscopic findings were studied in comparison with whole rat liver transplantation with rearterialization, 30% POLT and corresponding liver resections. After 70 and 30% POLT typical signs of hepatic regeneration were found, but no pathological alterations in the electron-microscopic picture. This POLT model might be helpful for the investigation of unresolved questions in 'splitting transplantation'.
Steinbauer
F
F
Department of Surgery, University of Erlangen, Germany.
Födra
C
C
Müller
V
V
Reck
T
T
Ernst
H
H
Kranz
D
D
Köckerling
F
F
D000818:Animals; D006085:Graft Survival; D008099:Liver / Q000502:physiology / Q000648:ultrastructure; D008115:Liver Regeneration; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008488:Medical Illustration; D008854:Microscopy, Electron; D051381:Rats; D011917:Rats, Inbred Lew