title: Effect of temperature and flow rate of irrigant on coagulation necrosis in canine prostate treated with neodymium:YAG laser.
abstract: We studied the effect of the irrigant temperature (5 degrees-38 degrees C) and flow rate (100-500 mL/min) on the extent of coagulation necrosis induced during Nd:YAG laser irradiation in the canine prostate model. The tissue response was quantified based on histopathologic evaluation of the lesions. Changing the irrigant temperature or the flow rate within the ranges studied did not significantly affect the size of the thermal lesions. The intraprostatic temperature distribution during laser irradiation is mainly governed by blood perfusion rather than by irrigant variables.
authors.affiliation: Division of Urology, Department of Surgery, University of Texas Medical Branch, Galveston, USA.
authors.forename: M
authors.initials: M
authors.lastname: LaHaye
authors.forename: M
authors.initials: M
authors.lastname: Pow-Sang
authors.forename: E
authors.initials: E
authors.lastname: Orihuela
authors.forename: M
authors.initials: M
authors.lastname: Motamedi
mesh_terms: D000818:Animals; D004285:Dogs; D017075:Laser Coagulation / Q000009:adverse effects*; D008297:Male; D009336:Necrosis; D011467:Prostate / Q000473:pathology / Q000601:surgery*; D012212:Rheology; D013696:Temperature; D007507:Therapeutic Irrigation