Immunoelectron microscopic study of HTLV-II-producing cells with an anti-envelope gp46 monoclonal antibody.
We observed expression of envelope gp46 protein on an HTLV-II-producing T-cell line (Mo) cells by an immunoelectron microscopical method using a monoclonal antibody against HTLV-II gp46. gp46 reactivity was observed on virus-like particles, extracellular vesicles, cell membrane, and partially in nuclear membrane and endoplasmic reticulum.
Ohara
N
N
Second Department of Pathology, Okayama University Medical School, Japan.
Hayashi
K
K
Miyamoto
K
K
Takahashi
K
K
Ohtsuki
Y
Y
Akagi
T
T
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000914:Antibodies, Viral / Q000276:immunology; D002460:Cell Line; D015686:Gene Products, env / Q000032:analysis* / Q000276:immunology / Q000378:metabolism / Q000648:ultrastructure; D015367:Human T-lymphotropic virus 2 / Q000276:immunology / Q000378:metabolism / Q000648:ultrastructure*; D006801:Humans; D051379:Mice; D016253:Microscopy, Immunoelectron; D015682:Retroviridae Proteins, Oncogenic / Q000032:analysis* / Q000276:immunology / Q000378:metabolism / Q000648:ultrastructure; D013601:T-Lymphocytes / Q000166:cytology; D014771:Virion / Q000276:immunology / Q000378:metabolism; D054299:env Gene Products, Human Immunodeficiency Virus
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D015686:Gene Products, env; D015682:Retroviridae Proteins, Oncogenic; D054299:env Gene Products, Human Immunodeficiency Virus; C069568:gp46 protein, Human immunodeficiency virus 2