Tuberous sclerosis and cardiac rhabdomyoma.
We conclude that echocardiographically detected cardiac rhabdomyomata are common in patients with tuberous sclerosis complex, and are more prevalent and prominent in the younger patient. Tumors regress in size or number, or both, in most patients aged < 4 years, and less so in older patients. Cardiac rhabdomyomata are associated with a higher incidence of preexcitation and may increase the risk for arrhythmia.
Nir
A
A
Department of Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA.
Tajik
A J
AJ
Freeman
W K
WK
Seward
J B
JB
Offord
K P
KP
Edwards
W D
WD
Mair
D D
DD
Gomez
M R
MR
D000293:Adolescent; D000367:Age Factors; D001145:Arrhythmias, Cardiac / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006352:Heart Ventricles; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012207:Rhabdomyoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012307:Risk Factors; D013997:Time Factors; D014402:Tuberous Sclerosis / Q000150:complications*