Neuroleptic malignant syndrome and lithium carbonate.
The authors describe a case of neuroleptic malignant syndrome that occurred in a patient on amitriptyline and lithium carbonate. They suggest that lithium-antidepressant combination can precipitate this syndrome. Intestinal pseudo-obstruction was a prominent feature in the patient in this study.
Fava
S
S
Department of Medicine, St. Luke's Hospital, Guardamangia, Malta, Europe.
Galizia
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AC
D000639:Amitriptyline / Q000008:administration & dosage / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000139:chemically induced / Q000175:diagnosis; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000209:etiology*
D000639:Amitriptyline; D016651:Lithium Carbonate