Dexamethasone downregulates mineralocorticoid receptors in A6 amphibian kidney cells in tissue culture.
Hagley
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RD
Division of Endocrinology and Metabolism, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-145, USA.
Watlington
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CO
D000450:Aldosterone / Q000494:pharmacology; D000663:Amphibians; D000818:Animals; D002460:Cell Line; D003345:Corticosterone / Q000494:pharmacology; D003907:Dexamethasone / Q000494:pharmacology*; D015536:Down-Regulation / Q000187:drug effects; D006854:Hydrocortisone / Q000494:pharmacology; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism*; D015735:Mifepristone / Q000494:pharmacology; D011965:Receptors, Glucocorticoid / Q000037:antagonists & inhibitors; D018161:Receptors, Mineralocorticoid / Q000187:drug effects* / Q000378:metabolism*
D011965:Receptors, Glucocorticoid; D018161:Receptors, Mineralocorticoid; D015735:Mifepristone; D000450:Aldosterone; D003907:Dexamethasone; D003345:Corticosterone; D006854:Hydrocortisone