title: Ischemic cerebrovascular disease and hormone therapy for infertility and transsexualism.
abstract: To highlight an emerging risk factor for stroke in the young, we report two patients who experienced ischemic cerebrovascular symptoms in unusual clinical settings of hormone therapy. Expanding indications for estrogenic therapy, including infertility and gender identity disorders, may constitute an emerging risk factor for ischemic stroke in young individuals.
authors.affiliation: Department of Neurology, Indiana University School of Medicine, Indianapolis, USA.
authors.forename: J
authors.initials: J
authors.lastname: Biller
authors.forename: J L
authors.initials: JL
authors.lastname: Saver
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology*; D002533:Cerebral Angiography; D004967:Estrogens / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014189:Transsexualism / Q000188:drug therapy*
chemical_list: D004967:Estrogens