Structure of the Arabidopsis RPM1 gene enabling dual specificity disease resistance.
Plants can recognize pathogens through the action of disease resistance (R) genes, which confer resistance to pathogens expressing unique corresponding avirulence (avr) genes. The molecular basis of this gene-for-gene specificity is unknown. The Arabidopsis thaliana RPM1 gene enables dual specificity to pathogens expressing either of two unrelated Pseudomonas syringae avr genes. Despite this function, RPM1 encodes a protein sharing molecular features with recently described single-specificity R genes. Surprisingly, RPM1 is lacking from naturally occurring, disease-susceptible Arabidopsis accessions.
Grant
M R
MR
Max-Delbrück Laboratory, Köln, Germany.
Godiard
L
L
Straube
E
E
Ashfield
T
T
Lewald
J
J
Sattler
A
A
Innes
R W
RW
Dangl
J L
JL
D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics* / Q000382:microbiology; D029681:Arabidopsis Proteins; D001483:Base Sequence; D005798:Genes, Bacterial; D017343:Genes, Plant; D005816:Genetic Complementation Test; D008969:Molecular Sequence Data; D009154:Mutation; D016366:Open Reading Frames; D010935:Plant Diseases / Q000235:genetics*; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D030821:Plants, Genetically Modified; D012150:Polymorphism, Restriction Fragment Length; D011549:Pseudomonas / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D014170:Transformation, Genetic; D014774:Virulence / Q000235:genetics
D029681:Arabidopsis Proteins; D010940:Plant Proteins; C095014:RPM1 protein, Arabidopsis