Psychiatric episodes in women with young children.
An historical cohort study was performed. Subjects were 118 pregnant women or mothers of children of < 3 years who were assessed at presentation to a psychiatric hospital and 5 years later. The relationship of episode onset to childbearing (during pregnancy or within 3 months of birth) was derived from psychiatric records at presentation and retrospectively determined by interview and life-event charting at follow-up. Determining childbearing status from records yielded an error rate of 30% compared with the status derived from direct interview. A change in diagnosis in the ChildBearing-Related Onset Illness (CBROI) category occurred in 50% of subjects. When Research Diagnostic Criteria were applied retrospectively to the presenting episodes, 95% of women with CBROI had affective disorder diagnoses. Clinicians in our intake setting often missed episodes of mania or hypomania in our subjects' histories.
Wisner
K L
KL
Mood Disorders Program, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Peindl
K S
KS
Hanusa
B H
BH
D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008016:Life Change Events; D008297:Male; D009035:Mothers / Q000523:psychology*; D016487:Parenting / Q000523:psychology*; D010552:Personality Assessment; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000523:psychology*; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology*; D011644:Puerperal Disorders / Q000175:diagnosis / Q000523:psychology*; D012189:Retrospective Studies