Renal vasculitis associated with ciprofloxacin.
We report two patients treated with ciprofloxacin who presented with acute renal failure. On renal biopsy, a necrotizing vasculitis was identified in addition to acute interstitial nephritis. Improvement in renal function resulted with the discontinuation of the antibiotic and the institution of immunosuppressive therapy.
Shih
D J
DJ
Department of Medicine, Rush Presbyterian St Lukes Medical Center, Chicago, IL 60612, USA.
Korbet
S M
SM
Rydel
J J
JJ
Schwartz
M M
MM
D000368:Aged; D000369:Aged, 80 and over; D002939:Ciprofloxacin / Q000009:adverse effects*; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000473:pathology; D008297:Male; D009336:Necrosis / Q000139:chemically induced; D009395:Nephritis, Interstitial / Q000139:chemically induced; D014657:Vasculitis / Q000139:chemically induced* / Q000473:pathology
D002939:Ciprofloxacin