Fulminant Mycoplasma pneumoniae pneumonia with marked elevation of serum soluble interleukin-2 receptor.
We treated a married couple who developed Mycoplasma pneumonia at the same time, and whose clinical courses and serum soluble interleukin-2 receptor (sIL-2R) levels were markedly different. The 30-year-old wife developed acute respiratory failure and her sIL-2R levels were extremely increased. After pulse therapy, her clinical state was improved, with a marked decrease in sIL-2R. In contrast, the 36-year-old husband, also suffered from the pneumonia with a moderate increase of sIL-2R, and recovered without any complications. The difference in their clinical states may be reflected in their serum sIL-2R levels, a marker of T cell activation in vivo.
Ito
S
S
Second Department of Internal Medicine, Fukui Medical School.
Abe
Y
Y
Kinomoto
K
K
Saitoh
T
T
Kato
T
T
Kohli
Y
Y
Kuriyama
M
M
Sakai
T
T
Ishizaki
T
T
D000208:Acute Disease; D000328:Adult; D005192:Family Health; D005260:Female; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification; D011019:Pneumonia, Mycoplasma / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D015375:Receptors, Interleukin-2 / Q000378:metabolism*; D012131:Respiratory Insufficiency / Q000209:etiology
D015375:Receptors, Interleukin-2