Flash P2 delay in primary degenerative dementia of the Alzheimer type.
1. Flash visual evoked responses of 31 patients meeting DSM-III-R criteria for primary degenerative dementia of the Alzheimer type were compared with 31 healthy controls. 2. P1 latency was normal (75 +/- 6 msec Alzheimer's; 75 +/- 6 msec controls). 3. P2 was significantly delayed (162 +/- 32 msec, 147 +/- 20 msec, p < 0.03) among patients. 4. P1-P2 interpeak latency was significantly increased (87 +/- 32 msec, 71 +/- 21 msec, p < 0.03) among patients.
Moore
N C
NC
Mercer University School of Medicine, Macon, Georgia, USA.
Tucker
K A
KA
Jann
M W
MW
Hostetler
R M
RM
Coburn
K L
KL
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000503:physiopathology; D001931:Brain Mapping; D004569:Electroencephalography; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D010775:Photic Stimulation; D014793:Visual Cortex / Q000503:physiopathology