title: [Acute renal failure associated with 5-aminosalicylic acid in inflammatory bowel disease].
abstract: A case of acute renal failure with characteristics of interstitial nephritis associated to treatment with mesalazine (5-ASA bound to resin) in a 26-year old patient with a 7-year history of Crohn's disease is presented. The patient had been previously treated with 5-ASA with no alterations in renal function being observed. Renal failure became manifest several days after initiation of maintenance therapy with 5-ASA during the latest outbreak of intestinal inflammatory disease and disappeared upon suppression of the drug.
authors.affiliation: Unidad de Aparato Digestivo, Hospital Regional Universitario Infanta Cristina, Universidad de Extremadura, Badajoz.
authors.forename: M
authors.initials: M
authors.lastname: García-Díaz
authors.forename: L
authors.initials: L
authors.lastname: Nevado
authors.forename: A
authors.initials: A
authors.lastname: Berenguer
authors.forename: J C
authors.initials: JC
authors.lastname: Bureo
authors.forename: P
authors.initials: P
authors.lastname: Bureo
authors.forename: J
authors.initials: J
authors.lastname: Sáenz de Santamaría
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000328:Adult; D000636:Aminosalicylic Acids / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D019804:Mesalamine
chemical_list: D000636:Aminosalicylic Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine
vernacular_title: Insuficiencia renal aguda asociada a ácido 5-aminosalicílico en la enfermedad inflamatoria intestinal.