Results of German multicenter study of antimicrobial susceptibilities of Trichophyton rubrum and Trichophyton mentagrophytes strains causing tinea unguium. German Collaborative Dermatophyte Drug Susceptibility Study Group.
Thirty-two strains of Trichophyton rubrum and 16 strains of Trichophyton mentagrophytes isolated from patients with tinea unguium in various parts of Germany were subjected to a microdilution test with six systemic or topical antimycotic agents. Apart from griseofulvin, there were no species-specific differences between the two species. Terbinafine was the most active antimycotic agent, with a MIC not exceeding 0.05 micrograms/ml.
Korting
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Dermatologische Klinik, Ludwig-Maximilians-Universität, Munich, Germany.
Ollert
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Abeck
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D000935:Antifungal Agents / Q000494:pharmacology*; D005858:Germany; D006118:Griseofulvin / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D014009:Onychomycosis / Q000382:microbiology*; D013045:Species Specificity; D014249:Trichophyton / Q000187:drug effects*
D000935:Antifungal Agents; D006118:Griseofulvin