title: Fat embolism syndrome caused by vegetable oil injection.
abstract: We present a case of fat embolism syndrome following vegetable oil injection for augmentation mammaplasty. Although vegetable oil is a stable neutral fat under usual storage conditions, it caused fat embolism and pulmonary injury in this patient. We investigated this mechanism by compound analysis of the injected oil, transbronchial lung biopsy and special staining of alveolar macrophages. This is the first description of the human response to vegetable oil injection. These data should aid in the investigation of the side effects of many types of lipids which may be applied to humans for various purposes in the future.
authors.affiliation: First Department of Internal Medicine, Tokyo Medical College.
authors.forename: H
authors.initials: H
authors.lastname: Kiyokawa
authors.forename: K
authors.initials: K
authors.lastname: Utsumi
authors.forename: K
authors.initials: K
authors.lastname: Minemura
authors.forename: I
authors.initials: I
authors.lastname: Kasuga
authors.forename: Y
authors.initials: Y
authors.lastname: Torii
authors.forename: M
authors.initials: M
authors.lastname: Yonemaru
authors.forename: Y
authors.initials: Y
authors.lastname: Ichinose
authors.forename: K
authors.initials: K
authors.lastname: Toyama
mesh_terms: D000328:Adult; D001706:Biopsy; D004620:Embolism, Fat / Q000209:etiology*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D016462:Mammaplasty / Q000009:adverse effects* / Q000379:methods; D010938:Plant Oils / Q000009:adverse effects*; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000473:pathology
chemical_list: D010938:Plant Oils