Trends in antimicrobial resistance of Streptococcus pneumoniae in Japan.
A total of 184 isolates of Streptococcus pneumoniae were recovered from the sputa of patients over a 5-year period in the Nagasaki area and were examined. A total of 30 strains were resistant to penicillin (MIC, > or = 0.10 micrograms/ml), 13 of which belonged to serotype 19B. These strains showed decreased susceptibility to other antimicrobial agents. Vancomycin, cefpirome, and imipenem were the most active agents tested.
Yoshida
R
R
Department of Laboratory Medicine, Nagasaki University School of Medicine, Japan.
Kaku
M
M
Kohno
S
S
Ishida
K
K
Mizukane
R
R
Takemura
H
H
Tanaka
H
H
Usui
T
T
Tomono
K
K
Koga
H
H
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013296:Streptococcus pneumoniae / Q000187:drug effects*
D000900:Anti-Bacterial Agents