CSF shunt physics: factors influencing inshunt CSF flow.
Cerebrospinal fluid (CSF) in a shunt does not have a constant flow rate. The flow fluctuates from 0.01 ml/min to 1.93 ml/min according to each patient's own daily supine rhythmic pattern. We determined and evaluated the factors influencing CSF flow in a shunt in 19 cases of hydrocephalus. Postural changes, such as head elevation, led to increases by over 0.04 ml/min in inshunt CSF flow, while inshunt CSF flow in the supine position was less than 0.04 ml/min. Respiratory changes, such as coughing and apnea-hyperventilation, also influenced inshunt CSF flow. Changes in intracranial pressure (ICP) corresponded to changes in inshunt CSF flow. Inshunt CSF flows were higher than average during the night, the flows being stimulated by increases in ICP especially during REM sleep.
Kadowaki
C
C
Department of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan.
Hara
M
M
Numoto
M
M
Takeuchi
K
K
Saito
I
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology*; D002557:Cerebrospinal Fluid Shunts / Q000295:instrumentation*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid / Q000601:surgery*; D007427:Intracranial Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D055585:Physical Phenomena; D010825:Physics; D011187:Posture / Q000502:physiology; D012123:Pulmonary Ventilation / Q000502:physiology; D012016:Reference Values; D012212:Rheology / Q000295:instrumentation