title: Cognitive event-related potential in hepatic encephalopathy.
abstract: A study of auditory P300 was performed on 24 patients with cirrhosis of the liver: 13 patients with hepatic encephalopathy (HE grade 1-2) and 11 patients without clinical encephalopathy (HE grade 0). The patients were also assessed using spontaneous EEG and neuropsychological methods: Mini Mental State, Digit Span and Number Connection Test. The P3 latency was found to be significantly increased in all patients (100%) with HE grade 1-2 and in 6 patients (54.5%) with HE grade 0. The clinical value of using the P300 latency in the hepatic encephalopathy is subsequently discussed.
authors.affiliation: Clinic of Neurology, University of Perugia, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Gallai
authors.forename: A
authors.initials: A
authors.lastname: Alberti
authors.forename: S
authors.initials: S
authors.lastname: Balò
authors.forename: G
authors.initials: G
authors.lastname: Mazzotta
authors.forename: C
authors.initials: C
authors.lastname: Clerici
authors.forename: G
authors.initials: G
authors.lastname: Gentili
authors.forename: C
authors.initials: C
authors.lastname: Firenze
authors.forename: A
authors.initials: A
authors.lastname: Morelli
mesh_terms: D000368:Aged; D001143:Arousal / Q000502:physiology*; D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006501:Hepatic Encephalopathy / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values