[Use of clofelin as an anesthetic and component of neurovegetative defense in ENT oncologic surgery].
Metabolism indices (blood sugar, lactic acid, pyruvic acid) and hemodynamics (mean arterial pressure, 1-hour diuresis) were measured in 41 hypertensive subjects undergoing resection or removal of the larynx for cancer under endotracheal anesthesia through tracheostoma. 18 patients of group 1 received calypsol anesthesia, whereas 23 patients of group 2 received combination of calypsol with clofelin. Croup 2 patients benefited more because clofelin potentiated the analgetic effect of calypsol, intensified neurovegetative block, promoted more rapid recovery of normal respiration, prolonged analgetic effect in postoperative period.
Leushin
S G
SG
Slepushkin
V D
VD
D000328:Adult; D000368:Aged; D000770:Anesthesia, Endotracheal; D000777:Anesthetics / Q000494:pharmacology*; D001341:Autonomic Nervous System / Q000187:drug effects*; D003000:Clonidine / Q000008:administration & dosage* / Q000494:pharmacology; D004357:Drug Synergism; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D007649:Ketamine / Q000494:pharmacology; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy; D008875:Middle Aged
D000777:Anesthetics; D007649:Ketamine; D003000:Clonidine
Ispol'zovanie klofelina v kachestve anestetika i komponenta neĭrovegetativnoĭ zashchity pri LOR-onkologicheskikh operatsiiakh.