title: Vitiligo: surgical repigmentation of leukotrichia.
abstract: BACKGROUND
  Patients with vitiligo frequently have premature gray hair. Until recently the literature was silent about its management. While surgically treating vitiligo, we incidentally observed repigmentation of gray hair.
  
  
  OBJECTIVE
  Based on our observations we undertook this study to see the effect of surgical treatment of vitiligo on repigmentation of leukotrichia, as well as to evaluate the percentage of repigmentation, if any, in the different hair-bearing areas, and the time taken for it.
  
  
  METHODS
  A case series of eight patients with nine patches of localized, stable, and refractory vitiligo with leukotrichia of 3-12 years duration is presented. The patients were followed up for 2-6 years. One patient was lost from follow-up after 2 months. The vitiligo was treated by dermabrasion and thin split-thickness skin grafting under local anesthesia, as outpatients.
  
  
  RESULTS
  Repigmentation of the hair occurred in all the areas but it was seen earlier (3 months) and was more complete in the eyebrows (70-95%). In the scalp and the beard areas it started later (6-9 months) and was around 50-60% only. The degree of pigmentation increased until about 3 years after surgery. No complications in the form of graft loss or alopecia were observed.
  
  
  CONCLUSIONS
  Partial to near-total repigmentation of leukotrichia can be achieved surgically. Contrary to the present theory, we hypothesize that melanocytes also migrate from the repigmented epidermis to the hair follicle, resulting in repigmentation of the hair.
authors.affiliation: Department of Plastic Surgery, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry, India.
authors.forename: K
authors.initials: K
authors.lastname: Agrawal
authors.forename: A
authors.initials: A
authors.lastname: Agrawal
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003869:Dermabrasion; D005260:Female; D006200:Hair Color; D006801:Humans; D008297:Male; D010858:Pigmentation; D016038:Skin Transplantation; D014820:Vitiligo / Q000601:surgery*