[Protective effect of total flavonoids of radix Astragali on mammalian cell damage caused by hydroxyl radical].
The protective effect of total flavonoids of Radix Astragali (TFA) on V79 cell damage caused by H2O2-Fe2+ system has been studied. The results show that total flavonoids of Radix Astragali inhibit lipid peroxides and increase SOD activity. It has also been found that TFA has different protective effect against various damages of V79 cells caused by hydroxyl radical.
Wang
D
D
Department of Biochemistry, General Hospital of PLA, Beijing.
Shen
W
W
Tian
Y
Y
Dong
Z
Z
Liu
G
G
Sun
Z
Z
Yang
S
S
Zhou
S
S
D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D003412:Cricetulus; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005347:Fibroblasts / Q000166:cytology; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology*; D017665:Hydroxyl Radical; D008054:Lipid Peroxides / Q000378:metabolism; D008168:Lung / Q000166:cytology*; D013482:Superoxide Dismutase / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D016166:Free Radical Scavengers; D008054:Lipid Peroxides; D017665:Hydroxyl Radical; D013482:Superoxide Dismutase