POEMS syndrome.
The principal features of POEMS syndrome are osteosclerotic bone lesions, peripheral sensorimotor neuropathy, and elevated levels of a monoclonal protein in the serum or urine. Skin lesions are present in the majority of patients with POEMS syndrome. Diffuse hyperpigmentation is the most common cutaneous finding. Hemangiomas with histopathological features resembling renal glomeruli are the most specific skin lesions.
Perniciaro
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Department of Dermatology, Mayo Clinic Jacksonville, FL 32224, USA.
D006801:Humans; D016878:POEMS Syndrome / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D012871:Skin Diseases / Q000473:pathology