Electrospray mass spectrometry for protein characterization.
Mass spectrometry is a venerable analytical tool that has been used for some time in biochemistry for the analysis of small molecules, such as steroids. More recently, physicists have solved the problems associated with vaporizing and ionizing proteins and peptides, thereby allowing mass spectrometry to take on new roles in investigating protein sequences, structures and modifications.
Mann
M
M
EMBL, Heidelberg, Germany.
Wilm
M
M
D013058:Mass Spectrometry / Q000379:methods*; D011506:Proteins / Q000737:chemistry*
D011506:Proteins