title: Changes of color vision in ocular hypertension.
abstract: Fifty-six ocular hypertension (OHT) patients were examined for 2-3 days in the Eye Clinic of Kuopio University Hospital. No glaucomatous changes were found. Twenty-seven of them were found to have several risk factors for developing glaucoma and medication was started. Twenty-nine of the patients did not show risk factors and had no medication. Color vision was examined with the Farnsworth-Munsell 100 (FM 100) hue test and Besançon anomalometer, later Color Vision Meter 712 at the beginning of the study and 3 years later. None of the 56 patients showed any glaucomatous changes after 3 years of the study. In the treatment group, the FM 100 test showed significantly (paired t-test, p = 0.004) improved error scores after 3 years. In the non-treatment group, 19 patients did not develop risk factors; they had no significant changes in the color vision results. In 10 patients of the non-treatment group, risk factors had developed with elevated intraocular pressure and medication was started for them after 3 years. Their color vision results in the blue anomalous quotient (AQ) of the anomalometer had significantly shifted to the blue part of the equation (paired t-test, p = 0.04). The other color vision results had not changed significantly. The significantly improved FM 100 scores in the treatment group could mean, that the treatment has a beneficial effect for the OHT eyes at risk for developing glaucoma.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Ophthalmology, University Hospital of Kuopio, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Mäntyjärvi
authors.forename: K
authors.initials: K
authors.lastname: Tuppurainen
mesh_terms: D000328:Adult; D000368:Aged; D003118:Color Perception / Q000502:physiology*; D003119:Color Perception Tests; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D012307:Risk Factors