title: Ductus-dependent aortic coarctation with a left-to-right shunt through the ductus: report of one case.
abstract: A 20 days old female baby presenting with dyspnea was found to have coarctation of the aorta and patent ductus arteriosus by echocardiography. The Doppler spectral display disclosed mainly a left-to-right shunt through the ductus. Therefore, the prostaglandin El infusion was discontinued. She developed acute left heart failure, and the echocardiograms at that time showed a markedly narrowed juxtaductal aortic coarctation with a closed ductus. After resumption of prostaglandin El, with an attenuated juxtaductal aortic coarctation, the left ventricular contractility and the systemic perfusion improved. Therefore, we conclude that the central role of a patent ductus in such a patient is to avoid the ductal constriction which will worsen the aortic coarctation.
authors.affiliation: Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
authors.forename: C F
authors.initials: CF
authors.lastname: Cheng
authors.forename: M H
authors.initials: MH
authors.lastname: Wu
authors.forename: J K
authors.initials: JK
authors.lastname: Wang
mesh_terms: D000527:Alprostadil; D001017:Aortic Coarctation / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy; D004374:Ductus Arteriosus, Patent / Q000150:complications* / Q000000981:diagnostic imaging; D018619:Echocardiography, Doppler, Pulsed; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016896:Treatment Outcome
chemical_list: D000527:Alprostadil