title: Determination of the mineral phases and structure of the bone-implant interface using Raman spectroscopy.
abstract: The bone-implant interface formed in a canine distal femur was examined by means of a Raman microprobe using an implant model designed to test calcium phosphate surface coatings. By using the 960 cm-1 band of calcium phosphate to characterize the interface and adjacent mineral, we obtained spatial and compositional information about the attachment of bone to the synthetic calcium phosphate coating on a titanium support. The interface between bone and the synthetic calcium phosphate is approximately 30-40 microns in width.
authors.affiliation: Department of Chemistry, Hospital for Joint Diseases, New York University, New York 10003, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Leung
authors.forename: M A
authors.initials: MA
authors.lastname: Walters
authors.forename: N C
authors.initials: NC
authors.lastname: Blumenthal
authors.forename: J L
authors.initials: JL
authors.lastname: Ricci
authors.forename: J M
authors.initials: JM
authors.lastname: Spivak
mesh_terms: D000818:Animals; D015519:Bone Density / Q000502:physiology*; D001842:Bone and Bones / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D002130:Calcium Phosphates / Q000032:analysis; D003460:Crystallization; D004285:Dogs; D019736:Prostheses and Implants; D013059:Spectrum Analysis, Raman; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
chemical_list: D002130:Calcium Phosphates; D014025:Titanium