[PCR genetic typing of pathogenic microorganisms].
Basic principles, characteristics, methodical peculiarities, and strategy of choice of PCR-mediated methods of genetic typing are discussed. Existing and potential fields of application of these methods for tackling many unsolved problems of molecular epidemiology of bacterial infections are considered. Advantages of PCR-mediated methods of genetic typing compared with other techniques used for studying genomic polymorphism are demonstrated. Possibilities for developing novel PCR-mediated methods with the aim of improving genetic typing are analyzed.
Shaginian
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IA
Gintsburg
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D001419:Bacteria / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D015373:Bacterial Typing Techniques; D001483:Base Sequence; D016172:DNA Fingerprinting; D017931:DNA Primers; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
D017931:DNA Primers
PTsR-geneticheskoe tipirovanie patogennykh mikroorganizmov.