Quercetin not only inhibits P-glycoprotein efflux activity but also inhibits CYP3A isozymes.
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MA
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000187:drug effects* / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D019392:Cytochrome P-450 CYP2E1; D065607:Cytochrome P-450 Enzyme Inhibitors; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D011794:Quercetin / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D065607:Cytochrome P-450 Enzyme Inhibitors; D007527:Isoenzymes; D011794:Quercetin; D006899:Mixed Function Oxygenases; D019392:Cytochrome P-450 CYP2E1