title: Comparative analysis of saphenous vein bypass vs. native coronary artery balloon angioplasty: technical differences and angiographic response.
abstract: To evaluate technical differences and angiographic response of saphenous vein bypass graft angioplasty in comparison to native coronary arteries, we retrospectively analyzed 54 patients undergoing this procedure at The Toronto Hospital between February 1988 and May 1993. These subjects were temporally matched to a cohort of successful native coronary angioplasties, with comparison of technical parameters, pre-existing qualitative/quantitative (Cardiac Measurement System) stenotic morphology, and angiographic response; including changes in minimum lumen diameter. Saphenous bypass graft angioplasty utilized larger balloons (CABG, 3.27 +/- 0.65 vs. native, 2.90 +/- 0.37 mm, P < .05), and higher inflation pressures (CABG, 10.1 +/- 3.7 vs. native, 8.8 +/- 2.5 atm, P < .05), although in a relative sense, balloon/artery ratios were similar (CABG, 1.09 +/- 0.20 vs. native, 1.03 +/- 0.15, pNS). Pre-procedural bypass graft lesions were more complex, with more frequent ACC/AHA type B1 lesions [CABG, 24/54 (44%) vs. native, 16/54 (30%), P < .05] and luminal thrombus [CABG, 17/54 (31%) vs. native, 6/54 (11%), P < .05]. Quantitative angiography revealed larger "reference" diameters within saphenous veins (CABG, 3.41 +/- 0.76 vs. native, 3.04 +/- 0.51 mm, P < .05), although minimum lumen diameter was less severe (CABG, 0.83 +/- 0.41 vs. native, 0.77 +/- 0.36, P < .05). In terms of balloon angioplasty response, greater improvement in luminal diameter was seen in bypass graft lesions (CABG, 1.55 +/- 0.53 vs. native, 1.32 +/- 0.44 mm, P < .05), with the largest changes within the "body" of the saphenous vein (ostial, 1.53 +/- 0.37; body, 1.68 +/- 0.50; anastomosis, 1.37 +/- 0.57 mm).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Medicine, Toronto Hospital (General Division), Ontario, Canada.
authors.forename: B P
authors.initials: BP
authors.lastname: Kimball
authors.forename: S
authors.initials: S
authors.lastname: Bui
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000601:surgery*; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D015331:Cohort Studies; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D004867:Equipment Design; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000601:surgery*; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000637:transplantation*; D016896:Treatment Outcome