title: [Synovectomy in rheumatoid arthritis].
abstract: Surgical synovectomy in the treatment of rheumatoid arthritis has been performed for more than a 100 years, and yet the definite indication has not been made clear. Synovectomy has a convincing, but mostly time-limited effect on pain and articular hydrops, but the radiological progression continues almost undisturbed. Histological evaluation of the regenerating synovial membrane has now shown a tendency towards reversing to baseline within about a year. The difficulties in evaluating the operation are caused by the lack of comparable randomized studies performed on large populations, treated in a double-blind fashion and examined in cooperation between surgeon and rheumatologist.
authors.affiliation: Fysiurgisk/reumatologisk afdeling U, Amtssygehuset i Gentofte.
authors.forename: C F
authors.initials: CF
authors.lastname: Lassen
authors.forename: C M
authors.initials: CM
authors.lastname: Jensen
authors.forename: C
authors.initials: C
authors.lastname: Tørholm
authors.forename: L M
authors.initials: LM
authors.lastname: Krohn
authors.forename: R
authors.initials: R
authors.lastname: Pelck
mesh_terms: D001172:Arthritis, Rheumatoid / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis; D000074402:Synovectomy; D013583:Synovial Membrane / Q000473:pathology
vernacular_title: Synovektomi ved reumatoid arthritis.