Trans fatty acids: a cause for concern?
The recommendation to reduce total and saturated fat is incorporated into the dietary guidelines for the general population in many western countries. In addition, dietary modification to reduce substantially the intake of saturated fats is a cornerstone of treatment in the hyperlipidaemias. Concern has recently been expressed regarding possible deleterious effects of trans isomers of unsaturated fatty acids on the lipoprotein profiles of both normo and hypercholesterolaemic persons. This review seeks to examine recent research in this area with a view to considering possible changes in the present dietary recommendations.
Chisholm
A
A
Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Mann
J
J
Skeaff
M
M
D003327:Coronary Disease / Q000209:etiology; D004041:Dietary Fats / Q000009:adverse effects*; D005231:Fatty Acids, Unsaturated / Q000009:adverse effects*; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D019301:Oleic Acid; D009829:Oleic Acids / Q000009:adverse effects; D013237:Stereoisomerism
D004041:Dietary Fats; D005231:Fatty Acids, Unsaturated; D008074:Lipoproteins; D009829:Oleic Acids; D019301:Oleic Acid; C011459:elaidic acid