title: Management of persistent lymphocele by sclerotherapy with doxycycline.
abstract: Three cases of lymphocele after lymphadenectomy for gynecologic malignancy are presented. These patients had large, symptomatic lymphoceles resistant to percutaneous catheter drainage. Sclerotherapy with a single dose of doxycycline was administered percutaneously to each patient. Single treatment achieved resolution in two patients. The third had a persistent lymphocele requiring excision. To our knowledge, doxycycline has not been used for sclerotherapy for lymphocele following radical gynecologic surgery. It may represent a viable addition to the conservative management of lymphoceles.
authors.affiliation: Department of Obstetrics and Gynecology, State University of New York Health Science Center, Syracuse 13210, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Folk
authors.forename: A G
authors.initials: AG
authors.lastname: Musa
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D004318:Doxycycline / Q000627:therapeutic use*; D016889:Endometrial Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision / Q000009:adverse effects; D008210:Lymphocele / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D015911:Sclerotherapy; D002583:Uterine Cervical Neoplasms / Q000601:surgery
chemical_list: D004318:Doxycycline