[Course of hay fever during the pollen season with respect to the effect of specific immunotherapy. II. Cytologic changes and chemotactic activity in nasal lavage].
The cytological changes and chemotactic activity in nasal lavage fluid were observed in 27 patients with pollen allergy. In one group of patients Pollinex was administered, but in the second--only placebo. Total cell count in nasal secretions was increased after pollen season. The significant increase of eosinophils and metachromatic cells was observed during the season in comparison with the time before and after it. No seasonal dynamic was documented in chemotactic activity of neutrophils in the nasal lavage fluid. Applied immunotherapy gave a some protection on evaluated parameters and observed symptoms.
Rozniecka
M
M
Kliniki Pneumonologii i Alergologii Instytutu Medycyny Wewnetrznej, Lodzi.
Kowałski
M L
ML
Grzegorczyk
J
J
Wojciechowska
B
B
Sliwińska-Kowalska
M
M
Rozniecki
J
J
D000328:Adult; D000485:Allergens / Q000627:therapeutic use*; D052179:Antigens, Plant / Q000627:therapeutic use; D002634:Chemotaxis, Leukocyte / Q000187:drug effects / Q000502:physiology*; D004338:Drug Combinations; D004804:Eosinophils / Q000276:immunology; D005260:Female; D005976:Glutaral / Q000627:therapeutic use*; D006801:Humans; D007167:Immunotherapy; D007958:Leukocyte Count; D008297:Male; D017817:Nasal Lavage Fluid / Q000166:cytology* / Q000276:immunology; D009504:Neutrophils / Q000502:physiology; D016011:Normal Distribution; D010936:Plant Extracts / Q000627:therapeutic use*; D006109:Poaceae; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D012621:Seasons; D018709:Statistics, Nonparametric; D014443:Tyrosine / Q000627:therapeutic use*
D000485:Allergens; D052179:Antigens, Plant; D004338:Drug Combinations; D010936:Plant Extracts; D014443:Tyrosine; C014155:Parietaria judaica pollen; D005976:Glutaral
Przebieg pyłkowicy w sezonie pylenia z uwzglednieniem wpływu immunoterapii swoistej Cześć II: Zmiany cytologiczne i aktywność chemotaktyczna w wydzielinie z nosa.