title: [A prospective study of perioperative antibiotic prophylaxis in reducing the rate of nosocomial infection among patients with intracranial tumors].
abstract: This paper analysed 525 intracranial neoplastic patients who were hospitalized from July, 1992 to June, 1993. The patients were randomly divided into control and experiment groups. In the experiment group, patients who received one kind of antibiotic during perioperation had a nosocomial infection rate of 6.29% (11/175), while the patients in the control group where antibiotics were routinely used as usual had a rate of 17.43% (61/350). There was a significant difference between the control (8.00%) and experiment group (2.29%) in terms of the intracranial infection incidence. Perioperative antibiotic prophylaxis showed great influence on the expenditure of antibiotics and duration of hospitalization in the patients with intracranial neoplastic tumors.
authors.affiliation: Tiantan Hospital, Beijing.
authors.forename: G H
authors.initials: GH
authors.lastname: Zhang
authors.forename: H Y
authors.initials: HY
authors.lastname: Cao
authors.forename: Y X
authors.initials: YX
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000601:surgery*; D002443:Ceftriaxone / Q000627:therapeutic use*; D002681:China / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000517:prevention & control*
chemical_list: D002443:Ceftriaxone