Molecular cellular mechanisms of training effects.
The review paper was composed in order to (1) discuss the mechanism responsible for the actualization of the adaptive protein synthesis in training, and (2) indicate the necessity for further studies in this field. Genome activation is common for systematic exercising. Depending on the specific nature, exercises result in the formation of metabolic and hormonal inductors acting on the cellular genetic apparatus. The final results of the adaptive protein synthesis are determined by the combination of influences exerted by transcription, translation and post-translation control.
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D000222:Adaptation, Physiological / Q000235:genetics; D004247:DNA / Q000235:genetics*; D015444:Exercise / Q000502:physiology*; D005786:Gene Expression Regulation; D006728:Hormones / Q000235:genetics; D006801:Humans; D018482:Muscle, Skeletal / Q000378:metabolism; D010806:Physical Education and Training; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational / Q000235:genetics; D011506:Proteins / Q000235:genetics; D014158:Transcription, Genetic
D006728:Hormones; D011506:Proteins; D004247:DNA