[The analgesic effect of galactosaminoglycuronoglycan in the treatment of osteoarthrosis].
The analgesic effect of galactosamineglucuronoglycan sulfate (GGG) was evaluated in a series of patients with moderate to severe coxarthrosis and gonarthrosis. GGG was used at the daily dose of 800 mg, in conjunction with indomethacin, for a period of 6 months. In compliance with this controlled study the results obtained were compared with those observed in another group of patients with similar pathologies who were treated with indomethacin alone. Statistical elaboration of the values "between times" and "between treatments" showed that the combined treatment led to significantly better results; tolerance was good and compliance by the patients satisfactory.
Consoli
G
G
Istituto di Reumatologia, Università degli Studi G. D'Annunzio, Pescara.
Di Matteo
L
L
Barlafante
G
G
Agostinone
A
A
Fratelli
V
V
D000328:Adult; D000368:Aged; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D000704:Analysis of Variance; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006025:Glycosaminoglycans / Q000627:therapeutic use*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010147:Pain Measurement
D018712:Analgesics, Non-Narcotic; D006025:Glycosaminoglycans; C080839:galactosamine glucuronoglycan sulfate; D007213:Indomethacin
Effetto antalgico del galattosaminglicuronoglicano nel trattamento dell'osteoartrosi.