title: Implants for spasticity.
abstract: In carefully selected groups of patients, intrathecal baclofen therapy offers well-proven benefits in reducing spasticity, notably in cases of spinal injury and multiple sclerosis. The initial costs of implantation are high, and there must be a long-term commitment by both patient and medical personnel to careful and proper management. Nevertheless, in suitable cases, the techniques should generally be properly considered before proceeding to any irreversible destructive neurosurgical procedure.
authors.affiliation: Department of Neurosurgery, Radcliffe Infirmary NHS Trust, Oxford, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Teddy
mesh_terms: D001418:Baclofen / Q000008:administration & dosage* / Q000009:adverse effects; D001921:Brain / Q000503:physiopathology; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004567:Electrodes, Implanted; D004867:Equipment Design; D006801:Humans; D015918:Infusion Pumps, Implantable; D007278:Injections, Spinal / Q000295:instrumentation*; D009046:Motor Neurons / Q000502:physiology; D009128:Muscle Spasticity / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation; D013116:Spinal Cord / Q000503:physiopathology
chemical_list: D001418:Baclofen