Correlation between UVA-induced changes in microviscosity, permeability and malondialdehyde formation in liposomal membrane.
The lipid peroxidation, 14C-glucose leakage and microviscosity of liposomal membrane increased linearly with increasing UVA fluence. A positive and highly significant correlation was found between these properties of the UVA-exposed liposomal membrane. The possible involvement of singlet oxygen in the UVA-induced damage of liposomal membrane is discussed.
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Biophysics Division, Saha Institute of Nuclear Physics, Calcutta, India.
Chatterjee
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D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects*; D002463:Cell Membrane Permeability / Q000528:radiation effects; D002784:Cholesterol / Q000737:chemistry; D004161:Diphenylhexatriene / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D008081:Liposomes; D008315:Malondialdehyde / Q000378:metabolism*; D014466:Ultraviolet Rays; D014783:Viscosity / Q000528:radiation effects
D008081:Liposomes; D004161:Diphenylhexatriene; D008315:Malondialdehyde; D002784:Cholesterol; D005947:Glucose