The estimation of inspired isoflurane concentration in a low-flow system.
We have examined the predictability of inspired isoflurane concentration during low-flow anaesthesia using a to-and-fro breathing system. Twenty one adult patients requiring mechanical ventilation of the lungs during surgery took part in this study. Using a fresh gas flow of 2 l.min-1, the ratio of inspired isoflurane concentration to isoflurane vaporizer setting was found to be approximately 4/5th after 5 min of anaesthesia. The ratio was maintained throughout the procedure, except for a few minutes following each change in vaporizer setting.
Gowrie-Mohan
S
S
Department of Anaesthesia, Hammersmith Hospital, London.
Chakrabarti
M K
MK
Lockwood
G G
GG
D000328:Adult; D000368:Aged; D000769:Anesthesia, Inhalation; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D013997:Time Factors
D007530:Isoflurane