New polyoxypregnane ester derivatives from Leptadenia hastata.
Six new polyoxypregnane esters [1-6] having sarcostin or deacetylmetaplexigenin as the aglycones, and acetyl, benzoyl, cinnamoyl, and nicotinoyl residues as the ester moieties linked at C-12 and/or at C-20, were isolated from Leptadenia hastata. In addition, three new glycosides [7-9] with D-cymarose and D-oleandrose linked at C-3 were present in the CHCl3 extract. Structures were deduced on the basis of spectral evidence.
Aquino
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Dipartimento de Chimica delle Sostanze Naturali, Università degli Studi ¿Federico II¿ di Napoli, Italy.
Pizza
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D002240:Carbohydrate Sequence; D004354:Drug Screening Assays, Antitumor; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010946:Plants, Medicinal / Q000737:chemistry*; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012675:Senegal; D014407:Tumor Cells, Cultured
D004952:Esters; D011278:Pregnanes