Recognition and control of neisserial infection by antibody and complement.
Immunity to neisserial infection involves complex interactions between antibody, complement and bacterial cell-surface molecules. Neisseria species express polysaccharide and glycolipid membrane components, which downregulate complement activation. The pathogenic potential of Neisseria depends on evasion of the complement cascade.
Jarvis
G A
GA
Dept of Laboratory Medicine, University of California, San Francisco 94121, USA.
D000907:Antibodies, Bacterial / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology; D002240:Carbohydrate Sequence; D003167:Complement Activation / Q000276:immunology*; D005260:Female; D006069:Gonorrhea / Q000276:immunology*; D006801:Humans; D008070:Lipopolysaccharides / Q000276:immunology; D008589:Meningococcal Infections / Q000276:immunology*; D008969:Molecular Sequence Data; D019158:N-Acetylneuraminic Acid; D012794:Sialic Acids / Q000378:metabolism
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D012794:Sialic Acids; C023023:lipid-linked oligosaccharides; D019158:N-Acetylneuraminic Acid