title: Pathogenicity of human and porcine intestinal spirochetes in one-day-old specific-pathogen-free chicks: an animal model of intestinal spirochetosis.
abstract: One-day-old chicks were infected orally with two strains of weakly hemolytic spirochetes isolated from a human and a pig with intestinal spirochetosis. These spirochetosis both colonized birds, attached end-on to their cecal enterocytes, induced watery diarrhea, and significantly depressed growth rates. Cultures of Serpulina innocens failed to colonize the chicks.
authors.affiliation: School of Veterinary Studies, Murdoch University, Australia.
authors.forename: D J
authors.initials: DJ
authors.lastname: Trott
authors.forename: A J
authors.initials: AJ
authors.lastname: McLaren
authors.forename: D J
authors.initials: DJ
authors.lastname: Hampson
mesh_terms: D000818:Animals; D017401:Brachyspira hyodysenteriae / Q000472:pathogenicity*; D002432:Cecum / Q000473:pathology / Q000648:ultrastructure; D002645:Chickens; D003967:Diarrhea / Q000209:etiology; D004195:Disease Models, Animal; D006801:Humans; D007410:Intestinal Diseases / Q000473:pathology*; D013047:Specific Pathogen-Free Organisms; D013145:Spirochaetales Infections / Q000473:pathology*; D013552:Swine