The treatment of refractory depression using paroxetine with lithium augmentation.
1. The case is described of a 68-year-old woman with DSM-III-R major depression who was treatment-resistant to paroxetine. 2. Low dose lithium addition, at a plasma level of 0.2 mM, led to a rapid and sustained remission of her illness.
Camprubi
M E
ME
Department of Psychiatry, Charing Cross Hospital, London, England.
Puri
B K
BK
D000368:Aged; D003866:Depressive Disorder / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D017374:Paroxetine / Q000627:therapeutic use*; D016896:Treatment Outcome
D016651:Lithium Carbonate; D017374:Paroxetine