Psychosis in Apert's syndrome with partial agenesis of the corpus callosum.
A 19-year-old male with Apert's syndrome developed psychotic symptoms that responded to haloperidol. He was also found to have partial agenesis of the corpus callosum and enlarged lateral ventricles on a head CT scan. The implications of these findings in the context of psychotic symptoms are discussed. There are no previous reports of psychosis in patients with Apert's syndrome.
Gupta
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Creighton-Nebraska Department of Psychiatry at VA Medical Center, Omaha 68105, USA.
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D000168:Acrocephalosyndactylia / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D000328:Adult; D061085:Agenesis of Corpus Callosum; D002552:Cerebral Ventricles / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology / Q000503:physiopathology; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D014057:Tomography, X-Ray Computed
D006220:Haloperidol