Pharmacology of incontinence.
Any type of filling or storage failure and urethral incontinence results from the following abnormalities: accommodation of increasing volumes of urine at a low intravesical pressure and with appropriate sensation, a bladder outlet that is closed at rest and remains so during increase in intra-abdominal pressure, and absence of involuntary bladder contraction. This article discusses the pharmacologic therapy that is effective in the management of many types of voiding dysfunction.
Wein
A J
AJ
Division of Urology, University of Pennsylvania School of Medicine, Philadelphia, USA.
D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects; D001743:Urinary Bladder / Q000187:drug effects / Q000503:physiopathology; D014549:Urinary Incontinence / Q000188:drug therapy* / Q000503:physiopathology; D014554:Urination / Q000187:drug effects