Fertilization and pregnancy achieved by intracytoplasmic injection of sperm retrieved from testicular biopsies.
OBJECTIVE
To determine if intracytoplasmic sperm injection using testicular sperm is effective in the treatment of infertile couples with obstructive azoospermia.


METHODS
Case report.


METHODS
Tertiary care teaching medical center.


METHODS
Intracytoplasmic sperm injection was performed in two patients using testicular sperm after microsurgical epididymal sperm aspiration failed.


RESULTS
In both cases fertilization and embryos resulted. One patient conceived and delivered triplets. There was no evidence of chromosomal abnormality or congenital malformation.


CONCLUSIONS
Intracytoplasmic sperm injection using sperm extracted from testicular biopsy appears to be effective in the treatment of infertile couples with obstructive azoospermia when microsurgical sperm aspiration fails.
Abuzeid
M I
MI
Department of Obstetrics and Gynecology, Hurley Medical Center, Flint, Michigan 48503, USA.
Chan
Y M
YM
Sasy
M A
MA
Basata
S
S
Beer
M
M
D000328:Adult; D001706:Biopsy; D003593:Cytoplasm; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D008297:Male; D008845:Microinjections; D009865:Oocytes / Q000648:ultrastructure*; D011247:Pregnancy; D011256:Pregnancy Outcome; D013094:Spermatozoa / Q000502:physiology; D013737:Testis / Q000166:cytology*; D014659:Vasectomy