title: Brevitaxin, a new diterpenolignan from the bark of Taxus brevifolia.
abstract: The first terpenolignan, brevitaxin [1], has been isolated from the bark of Taxus brevifolia. Identification was carried out using spectral methods, and the regiochemistry and cytotoxicity of 1 are discussed.
authors.affiliation: Hauser Chemical Research, Inc., Boulder, Colorado 80301, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Arslanian
authors.forename: D T
authors.initials: DT
authors.lastname: Bailey
authors.forename: M C
authors.initials: MC
authors.lastname: Kent
authors.forename: S L
authors.initials: SL
authors.lastname: Richheimer
authors.forename: K R
authors.initials: KR
authors.lastname: Thornburg
authors.forename: D W
authors.initials: DW
authors.lastname: Timmons
authors.forename: Q Y
authors.initials: QY
authors.lastname: Zheng
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D017705:Lignans / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D017705:Lignans; C094788:brevitaxin