title: Short vs. long-term calcium hydroxide treatment of established inflammatory root resorption in replanted dog teeth.
abstract: This study examined, histologically, the healing of intentionally produced inflammatory root resorption of replanted teeth in beagle dogs, treated with short- or long-term placement of calcium hydroxide. Thirty beagle dog incisors were randomly divided into four groups. In group 1 (negative control), uninfected incisors were extracted, the roots were longitudinally grooved and the teeth were replanted within 2 min. In group 2 the root canals were artificially infected followed by extraction, longitudinal grooving, and replantation as in group 1. Radiographs were taken biweekly and at the first signs of inflammatory root resorption or at 4 weeks, the root canals were fully instrumented and medicated with calcium hydroxide. In group 2, the root canals were permanently obturated with gutta-percha and sealer after 1 week of calcium hydroxide. The teeth in group 3 were treated as described in group 2 but after 1 wk the calcium hydroxide dressing was repacked for the duration of the study. In group 4 (positive control) the teeth were treated as described in groups 2 and 3 but no endodontic treatment was performed. Twelve weeks after the initiation of the endodontic treatment, sacrifice and histological preparation were carried out. In group 1, complete cemental repair was seen in all teeth. In group 2, five of ten teeth showed complete cemental repair whereas in group 3 complete cemental repair was seen in nine of ten teeth. None of the teeth in group 4 showed cemental repair. It was concluded that long-term may be more effective than short-term calcium hydroxide treatment of established inflammatory root resorption.
authors.affiliation: School of Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA.
authors.forename: M
authors.initials: M
authors.lastname: Trope
authors.forename: J
authors.initials: J
authors.lastname: Moshonov
authors.forename: R
authors.initials: R
authors.lastname: Nissan
authors.forename: P
authors.initials: P
authors.lastname: Buxt
authors.forename: C
authors.initials: C
authors.lastname: Yesilsoy
mesh_terms: D000818:Animals; D002126:Calcium Hydroxide / Q000627:therapeutic use*; D004285:Dogs; D007180:Incisor; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012390:Root Canal Therapy; D012391:Root Resorption / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D013997:Time Factors; D014090:Tooth Replantation / Q000009:adverse effects
chemical_list: D012388:Root Canal Irrigants; D002126:Calcium Hydroxide