Preventive actions of Terminalia belerica in experimentally induced atherosclerosis.
Hypercholesterolaemia and atherosclerosis were induced experimentally in rabbits by cholesterol feeding. The effect of an indigenous drug, T. belerica, was evaluated in these hypercholesterolemic rabbits. T. belerica reduced the levels of lipids in hypercholesterolemic animals. There was also a significant decrease in liver lipids and heart lipids (P < 0.05) in the drug-treated animals.
Shaila
H P
HP
Department of Biochemistry, Kasturba Medical College, Manipal, Karnataka, India.
Udupa
A L
AL
Udupa
S L
SL
D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000378:metabolism / Q000517:prevention & control*; D001219:Aspartate Aminotransferases / Q000097:blood; D002784:Cholesterol / Q000032:analysis / Q000097:blood; D004036:Diet, Atherogenic; D006937:Hypercholesterolemia / Q000097:blood / Q000378:metabolism / Q000517:prevention & control; D008099:Liver / Q000737:chemistry; D008297:Male; D008515:Medicine, Ayurvedic; D009206:Myocardium / Q000737:chemistry; D010743:Phospholipids / Q000097:blood / Q000378:metabolism; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011817:Rabbits; D014280:Triglycerides / Q000032:analysis / Q000097:blood
D010743:Phospholipids; D010936:Plant Extracts; D014280:Triglycerides; D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase