title: [Symptomatic primary biliary stenosis without cholestasis].
abstract: The case of a 59-years old patient with typical clinical manifestations of primary biliary cirrhosis (PBC): pruritus, asthenia, arthralgias and dry syndrome, with skin pigmentation and AMA positivity, hypergammaglobulinemia and an elevation of IgM is presented. Liver biopsy was compatible with stage II PBC. No analytical data of cholestasis, has been seen over 26 months of follow up with normal transaminases, alkaline phosphatase, gamma-glutamyltranspeptidase and cholesterol. The absence of cholestasis in the presence of symptoms is of interest.
authors.affiliation: Sección de Aparato Digestivo, Hospital Rio Hortega, Valladolid.
authors.forename: M R
authors.initials: MR
authors.lastname: Velicia Llames
authors.forename: J M
authors.initials: JM
authors.lastname: González Hernández
authors.forename: P
authors.initials: P
authors.lastname: Fernández Orcajo
authors.forename: C
authors.initials: C
authors.lastname: Sanz Santacruz
mesh_terms: D004796:Clinical Enzyme Tests; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D013997:Time Factors
vernacular_title: Cirrosis biliar primaria sintomática sin colestasis.