title: Congenital and acquired syphilis of bone: pathologic fracture with hyperplastic callus. A description of two cases and a review of the literature.
abstract: The authors describe two cases of syphilis of bone with multiple pathologic fractures. Healing of the fractures occurred over a normal period of time, with the production of hyperplastic callus. Differential diagnosis with tumorous and pseudotumorous lesions is possible based on clinical data and a history of the patient, as well as specific laboratory tests for syphilis; occasionally, biopsy is required.
authors.affiliation: Ia Clinica Ortopedica dell'Università, Istituto Rizzoli, Bologna.
authors.forename: L
authors.initials: L
authors.lastname: Campanacci
authors.forename: R
authors.initials: R
authors.lastname: Casadei
authors.forename: F
authors.initials: F
authors.lastname: De Iure
authors.forename: S
authors.initials: S
authors.lastname: Bandiera
mesh_terms: D000328:Adult; D001847:Bone Diseases / Q000150:complications*; D002146:Bony Callus; D002648:Child; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology* / Q000601:surgery; D006801:Humans; D006965:Hyperplasia; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D013587:Syphilis / Q000150:complications*; D013590:Syphilis, Congenital / Q000150:complications* / Q000188:drug therapy
chemical_list: D010406:Penicillins