title: Drug-related fatal anaphylactic shock in Denmark 1968-1990. A study based on notifications to the Committee on Adverse Drug Reactions.
abstract: Based on notifications to the Danish Committee on Adverse Drug Reactions and to the Central Death Register, 30 cases of fatal drug-induced anaphylactic shock were identified during the period 1968-1990. The most frequent causes were contrast media for X-ray examinations, antibiotics, and extracts of allergens. Nine cases occurred outside hospital; they were mainly caused by the use of allergen extracts of moulds for desensitization in general practice. Fatal drug-induced anaphylactic shock is rare, estimated in the present study at 0.3 case per million inhabitants per year.
authors.affiliation: Department of Anaesthesiology, Aalborg Hospital, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Lenler-Petersen
authors.forename: D
authors.initials: D
authors.lastname: Hansen
authors.forename: M
authors.initials: M
authors.lastname: Andersen
authors.forename: H T
authors.initials: HT
authors.lastname: Sørensen
authors.forename: H
authors.initials: H
authors.lastname: Bille
mesh_terms: D000293:Adolescent; D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens / Q000009:adverse effects*; D000707:Anaphylaxis / Q000139:chemically induced* / Q000453:epidemiology / Q000401:mortality*; D003287:Contrast Media / Q000009:adverse effects; D003718:Denmark / Q000453:epidemiology; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017891:Pharmacoepidemiology; D012042:Registries
chemical_list: D000485:Allergens; D003287:Contrast Media