title: Rhabdomyolysis complicating acute Epstein-Barr virus infection.
abstract: Infection with Epstein-Barr virus (EBV) is common and induces a broad spectrum of illness. In the majority of cases the disease manifests with typical signs of heterophile-positive infectious mononucleosis in which myalgia may be seen in up to 20% of cases. In this study, a case of rhabdomyolysis is reported occurring during the clinical course of an 18-year-old patient with infectious mononucleosis. This severe form of muscle involvement has been rarely associated with EBV infections. Five similar cases previously published in the English literature are also reviewed. The clinical implications of rhabdomyolysis and infectious mononucleosis are discussed.
authors.affiliation: Dept. of Internal Medicine I, Rambam Medical Center, Faculty of Medicine, Technionrael Institute of Technology, Haifa, Israel.
authors.forename: H
authors.initials: H
authors.lastname: Osamah
authors.forename: R
authors.initials: R
authors.lastname: Finkelstein
authors.forename: J G
authors.initials: JG
authors.lastname: Brook
mesh_terms: D000293:Adolescent; D000077324:Crystalloid Solutions; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D007552:Isotonic Solutions; D008297:Male; D010952:Plasma Substitutes / Q000627:therapeutic use; D012206:Rhabdomyolysis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D017693:Sodium Bicarbonate / Q000627:therapeutic use
chemical_list: D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D010952:Plasma Substitutes; D017693:Sodium Bicarbonate