Management of persistent lymphocele by sclerotherapy with doxycycline.
Three cases of lymphocele after lymphadenectomy for gynecologic malignancy are presented. These patients had large, symptomatic lymphoceles resistant to percutaneous catheter drainage. Sclerotherapy with a single dose of doxycycline was administered percutaneously to each patient. Single treatment achieved resolution in two patients. The third had a persistent lymphocele requiring excision. To our knowledge, doxycycline has not been used for sclerotherapy for lymphocele following radical gynecologic surgery. It may represent a viable addition to the conservative management of lymphoceles.
Folk
J J
JJ
Department of Obstetrics and Gynecology, State University of New York Health Science Center, Syracuse 13210, USA.
Musa
A G
AG
D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D004318:Doxycycline / Q000627:therapeutic use*; D016889:Endometrial Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision / Q000009:adverse effects; D008210:Lymphocele / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D015911:Sclerotherapy; D002583:Uterine Cervical Neoplasms / Q000601:surgery
D004318:Doxycycline