title: Pituitary apoplexy into nonadenomatous tissue: case report and review.
abstract: Pituitary apoplexy into nonadenomatous tissue is extremely rare. The authors describe a 20-year-old woman with symptomatic pituitary hemorrhage into an apparently intrasellar malignant teratoma, which caused headache, visual impairment, involvement of III, IV, VI, and 1st division of the V cranial nerves, and hypopituitarism. Diabetes insipidus had developed previously. Magnetic resonance scans had a high-intensity signal in the pituitary on T1- and T2-weighted images, and lack of the signal of the posterior pituitary. Transsphenoidal approach, radiotherapy, and chemotherapy management did not preclude a fatal outcome.
authors.affiliation: Department of Endocrinology, Universidad de Barcelona, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández-Real
authors.forename: C
authors.initials: C
authors.lastname: Villabona
authors.forename: J J
authors.initials: JJ
authors.lastname: Acebes
authors.forename: J M
authors.initials: JM
authors.lastname: Gómez-Sáez
authors.forename: J
authors.initials: J
authors.lastname: Soler
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010899:Pituitary Apoplexy / Q000209:etiology / Q000401:mortality / Q000503:physiopathology*; D010911:Pituitary Neoplasms / Q000150:complications / Q000401:mortality / Q000503:physiopathology*; D013724:Teratoma / Q000150:complications / Q000401:mortality / Q000503:physiopathology*