The enamelin (tuftelin) gene.
This paper reviews the primary structure, characteristics and possible function of tuftelin/enamelin protein. It describes the distribution of tuftelin in the ameloblast cell and in the extracellular enamel matrix, employing high resolution protein-A gold immunocytochemistry. The chromosomal localization of the human tuftelin gene and its possible involvement in autosomally linked Amelogenesis Imperfecta, the most common hereditary disease of enamel, is also discussed.
Deutsch
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D
Department of Oral Biology, Hebrew University, Hadassah Faculty of Dental Medicine, Jerusalem, Israel.
Palmon
A
A
Dafni
L
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Catalano-Sherman
J
J
Young
M F
MF
Fisher
L W
LW
D000565:Ameloblasts / Q000737:chemistry; D000567:Amelogenesis Imperfecta / Q000235:genetics; D000818:Animals; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D003746:Dental Enamel Proteins / Q000032:analysis / Q000737:chemistry / Q000235:genetics*; D005109:Extracellular Matrix / Q000737:chemistry; D006801:Humans
D003746:Dental Enamel Proteins; C038456:tuftelin