title: [Bendazac hepatotoxicity: analysis of 16 cases].
abstract: Hepatic lesions induced by non-steroid antiinflammatory drugs are a common cause of disease, particularly among elderly patients. Although its clinical expression is polymorphous, occasional increases in serum transaminase values predominate. Sixteen cases of liver involvement by bendazac were studied. This NSAID is used in Spain for the treatment of cataracts, from a total of 112 patients observing such therapy. The clinical spectrum of liver disease induced by bendazac is discussed and emphasis is placed on the necessity to judiciously select the indications for NSAIDs.
authors.affiliation: Servicio de Medicina Interna, Hospital Santos Reyes, Aranda de Duero, Burgos.
authors.forename: J M
authors.initials: JM
authors.lastname: Prieto de Paula
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez Rodríguez
authors.forename: V
authors.initials: V
authors.lastname: Villamandos Nicás
authors.forename: H
authors.initials: H
authors.lastname: Sanz de la Fuente
authors.forename: A
authors.initials: A
authors.lastname: Prada Mínguez
authors.forename: A
authors.initials: A
authors.lastname: del Portillo Rubí
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D002386:Cataract / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007191:Indazoles / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007191:Indazoles; C000123:bendazac
vernacular_title: Hepatotoxicidad por bendazaco: análisis de 16 casos.