title: Sustained attention, activation and MPH in ADHD: a research note.
abstract: Sustained attention was studied in children with attention deficit hyperactivity disorder (ADHD) and normal controls using a continuous performance task with slow presentation of stimuli and carried out with an experimenter-present and absent condition. Children with ADHD were slower than controls, with performance deteriorating over time, particularly in the experimenter-absent condition. Both the slowness and deterioration normalized when the children received MPH. Hence the rate of stimuli presentation and the presence or absence of experimenter are both crucial factors in the performance of children with ADHD. MPH is able to ameliorate the performance decrement seen under these conditions.
authors.affiliation: Department of Experimental Clinical Psychology, University of Groningen, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: van der Meere
authors.forename: R
authors.initials: R
authors.lastname: Shalev
authors.forename: N
authors.initials: N
authors.lastname: Börger
authors.forename: V
authors.initials: V
authors.lastname: Gross-Tsur
mesh_terms: D001288:Attention / Q000187:drug effects*; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology*; D002648:Child; D018592:Cross-Over Studies; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology* / Q000627:therapeutic use*; D010919:Placebos; D011569:Psychiatric Status Rating Scales; D016896:Treatment Outcome
chemical_list: D010919:Placebos; D008774:Methylphenidate