title: Evaluation of serum beta 2-microglobulin in premalignant and malignant lesions of the oral cavity.
abstract: Serum beta-2-microglobulin was estimated in patients with oral leukoplakia, oral submucous fibrosis, and oral cancer. The results were compared with that of an equal number of age- and sex-matched healthy controls. A definite increase in the level of beta 2-microglobulin was observed in patients with oral submucous fibrosis and oral cancer. Though the level of beta 2-microglobulin was found to be high in oral leukoplakia, it was not statistically significant. Further studies will validate the role of beta 2-microglobulin estimation to predict the malignant potential of oral submucous fibrosis.
authors.affiliation: Dental College, Trivandrum, Kerala, India.
authors.forename: S
authors.initials: S
authors.lastname: Anil
authors.forename: V T
authors.initials: VT
authors.lastname: Beena
authors.forename: R G
authors.initials: RG
authors.lastname: Nair
authors.forename: T
authors.initials: T
authors.lastname: Vijayakumar
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000097:blood*; D009914:Oral Submucous Fibrosis / Q000097:blood*; D001613:beta 2-Microglobulin / Q000032:analysis*
chemical_list: D014408:Biomarkers, Tumor; D001613:beta 2-Microglobulin