title: Production of monoclonal antibody against hepatitis B surface antigen.
abstract: HBV infection is a major health problem in Southeast Asia. Thailand is considered to be an endemic area of HBV infection(18). Prevalence of HBsAg carriers is 5.2 per cent in children, 9 per cent in adults and 5.6 per cent in pregnant women(19,20). We believe that the monoclonal antibody described in the present report will be useful to develop HBsAg-KIT for national serologic screening assay, as considered in terms of sensitivity, specificity and cost effectiveness.
authors.affiliation: Institute of Pre-Clinical Sciences, Faculty of Medicine, Thammasat University, Pratumthani, Thailand.
authors.forename: W
authors.initials: W
authors.lastname: Tangkananond
authors.forename: W
authors.initials: W
authors.lastname: Charoensiriwatana
authors.forename: A
authors.initials: A
authors.lastname: Vanichanon
authors.forename: N
authors.initials: N
authors.lastname: Janejai
authors.forename: N
authors.initials: N
authors.lastname: Wetprasit
authors.forename: P
authors.initials: P
authors.lastname: Shewsuwan
authors.forename: B
authors.initials: B
authors.lastname: Pojanagaroon
authors.forename: S
authors.initials: S
authors.lastname: Saguanwonge
authors.forename: J
authors.initials: J
authors.lastname: Bhumisawasdi
authors.forename: C
authors.initials: C
authors.lastname: Jayavasu
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006509:Hepatitis B / Q000175:diagnosis* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D012680:Sensitivity and Specificity; D012698:Serologic Tests
chemical_list: D000911:Antibodies, Monoclonal; D006514:Hepatitis B Surface Antigens