title: MR signal changes in bone marrow of mandible in hematologic disorders.
abstract: OBJECTIVE
  Signal intensity changes in bone marrow of the mandible were observed in cases with hematologic disorders.
  
  
  METHODS
  Using MRI, bone marrow intensity of the mandible was observed in six patients with polycythemia vera, acute leukemia, myelofibrosis, and malignant lymphoma. A control group was also evaluated for comparison.
  
  
  RESULTS
  The bone marrow of the condyloid process of the mandible converts to yellow marrow in early childhood. Therefore, T1-weighted imaging showed the marrow of the mandible to have a high signal intensity similar to that of fat in the control cases. In contrast, the bone marrow of the mandible in the patients exhibited lower intensity than that of fat and was enhanced after Gd-DTPA injection.
  
  
  CONCLUSIONS
  In hematologic diseases MRI detected the signal changes of the mandible. More attention should be focused on the marrow intensity of the mandible in the routine cranial MR examinations in patients with hematologic disorders.
authors.affiliation: Department of Radiology, Nippon Medical School, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Amano
authors.forename: H
authors.initials: H
authors.lastname: Wakabayashi
authors.forename: T
authors.initials: T
authors.lastname: Kumazaki
mesh_terms: D000293:Adolescent; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D016022:Case-Control Studies; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006402:Hematologic Diseases / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008334:Mandible / Q000473:pathology*; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA