title: [Inflammatoru bowel disease in Aragón: a more and more frequent diagnosis].
abstract: OBJECTIVE
  To study the frequency of inflammatory bowel disease in our area.
  
  
  METHODS
  A retrospective, hospital-based analysis identifying potential cases, with a posterior study of case records following a predefined protocol, according to international standards in diagnosis.
  
  
  METHODS
  All patients with a confirmed diagnosis of Crohn's disease, ulcerative colitis, or indeterminate colitis established between 1975 and 1992 at our Hospital.
  
  
  RESULTS
  222 cases (ulcerative colitis: 109; Crohn's disease 93; indeterminate colitis 20) were identified and a clear trend for an increased incidence was found for the three diagnoses; with annual incidence below 1 for them all in the 1975-1977 period versus 3.66; 3.33; and 1 respectively in the 1990-1992 period. This trend was evident both for ulcerative colitis and Crohn's disease.
  
  
  CONCLUSIONS
  The global frequency of inflammatory bowel disease has increased in the last years in Zaragoza (Spain), and its incidence in now very similar to that reported in northern European countries. Possible factors associated with this phenomenon should be pursued in future studies.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Clínico Universitario Lozano Blesa, Zaragoza.
authors.forename: J
authors.initials: J
authors.lastname: Cella Lanau
authors.forename: J
authors.initials: J
authors.lastname: López Zaborras
authors.forename: F
authors.initials: F
authors.lastname: Gomollón García
authors.forename: R
authors.initials: R
authors.lastname: Sáinz Samitier
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology
vernacular_title: Enfermedad inflamatoria intestinal en Aragón: un diagnóstico cada vez más frecuente.