title: [Morphology and biological integration of autodermoplasties in large incisional hernias. Results of an experimental study].
abstract: Their aim of the experimental study was to investigate the morphology and wound healing of "Kutisplastik"-technique, originally introduced by Loewe (1913) and Rehn (1914), from different conditions. We want to clarify the mechanism and development of revascularisation.
  
  
  RESULTS
  The well known phases of wound healing also appear in the situation of a cutisplasty. In the exsudative reaction the cutis is covered from fibrin fibers. This leads to the development of granulation tissue. The cellular reaction demonstrates first the in-growth of capillary bundles and vessels in the collagen network of corium. The revascularisation is finished up to 14 days after the operation. The other part is the immigration of granulocytes and macrophages in the graft. The release of enzymes leads to the lysis of epidermal structures, cutaneous appendages and at least to collagen fibers of corium. There is also a proliferation from fibroblasts. The genesis from new collagen fibers is then observed so a scar tissue reveals. The "Kutisplastik"-technique contains that the epidermal side of the graft is turned upside-down towards the peritoneum and is sutured under as high tension as possible to the healthy fascia around. This morphology of healing is seen only under high-tension suturing. In the experimental mode of non-tension suturing there is a lack of success in cutisplasty for abdominal wall defects.
authors.affiliation: Clinique Chirurgicale Universitaire In der Schornau 23, Bochum.
authors.forename: H B
authors.initials: HB
authors.lastname: Reith
authors.forename: H
authors.initials: H
authors.lastname: Dittrich
authors.forename: W
authors.initials: W
authors.lastname: Kozuschek
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006555:Hernia, Ventral / Q000601:surgery*; D051381:Rats; D017208:Rats, Wistar; D016038:Skin Transplantation / Q000379:methods*; D013524:Surgical Flaps; D013552:Swine; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology*
vernacular_title: Morphologie et intégration biologique des auto dermoplasties dans les grandes éventrations. Résultats d'une étude expérimentale.