title: Implementation of multiple isocentre treatment for dynamic radiosurgery.
abstract: Radiosurgery using the dynamic rotation technique with a single isocentre was introduced at the Toronto-Bayview Regional Cancer Centre (T-BRCC) in 1988. Since then, over 100 patients have been treated. It was soon recognized that 25-30% of patients were referred with either non-spherical lesions or multiple lesions located sufficiently close together that consideration had to be given to the overlapping dose distributions throughout the treated volume. To treat these more complex targets a multiple isocentre technique was developed which also took account of these effects and the resulting normalization problem. This technique was implemented in September 1992. Comparisons between calculated doses and actual doses delivered have been undertaken using a spherical phantom containing radiochromic film. Measured dose distributions agreed with the planned distributions to within +/- 1 mm. The effect of multiple isocentres on the penumbra of dose distributions has been examined. The methods adopted for the normalization of treatment plans and clinical examples illustrating the application of the multiple isocentre technique are presented.
authors.affiliation: Division of Medical Physics, Toronto Sunny Brook Regional Cancer Centre, North York, Ontario, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Ramani
authors.forename: P F
authors.initials: PF
authors.lastname: O'Brien
authors.forename: P
authors.initials: P
authors.lastname: Davey
authors.forename: M L
authors.initials: ML
authors.lastname: Schwartz
authors.forename: C S
authors.initials: CS
authors.lastname: Young
authors.forename: A W
authors.initials: AW
authors.lastname: Lightstone
authors.forename: D L
authors.initials: DL
authors.lastname: Mason
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000556:secondary / Q000601:surgery*; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000601:surgery*; D008875:Middle Aged; D016634:Radiosurgery / Q000379:methods*; D011879:Radiotherapy Dosage; D016896:Treatment Outcome