Infrequent sites of extramedullary relapse after allogeneic bone marrow transplantation.
In the present report, we describe two cases of rare extramedullary relapse (skin, muscle) after allogeneic bone marrow transplantation (BMT). As both patients were male and had received sex mismatched (non T-depleted) BMT, marrow samples were analysed with a Y-chromosome specific probe allowing the sensitive detection of host DNA. The proportion of host DNA remained low in all post BMT samples from these patients, even at the time of extramedullary relapse.
Viard
F
F
Laboratoire d'Hématologie, Université de Bordeaux II, France.
Bilhou-Nabera
C
C
Marit
G
G
Durrieu
F
F
Dubus
P
P
Masseron
T
T
Boiron
J M
JM
Gharbi
M J
MJ
Salzes
S
S
Broustet
A
A
D000328:Adult; D016026:Bone Marrow Transplantation; D006801:Humans; D007938:Leukemia / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012008:Recurrence