title: Effect of various levels of T-2 toxin on the clinical status, performance and metabolism of growing pigs.
abstract: In two sets of experiments eight groups of seven-week-old pigs weighing about 9 kg were fed for three weeks a prestarter that contained 0.5, 1.0, 2.0, 3.0, 4.0, 5.0, 10.0 or 15.0 mg/kg of highly purified T-2 toxin. The feed of the two control groups was free from T-2 toxin. Average daily intakes of toxin by the pigs were 0.38, 0.81, 1.24, 1.43, 0.93, 0.81, 0.99 and 2.5 mg, respectively. The weight gains, the feed intakes, the extent of feed refusal, the parameters of energy and protein metabolism and the serum concentrations of calcium, inorganic phosphorus and magnesium were affected to different extents by the different doses of T-2 toxin, but the data indicated that feed consumption was reduced and the activity of aspartate aminotransferase was increased by the smallest amount of T-2 toxin tested.
authors.affiliation: Department of Animal Hygiene, University of Veterinary Science, Budapest, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Rafai
authors.forename: A
authors.initials: A
authors.lastname: Bata
authors.forename: A
authors.initials: A
authors.lastname: Ványi
authors.forename: Z
authors.initials: Z
authors.lastname: Papp
authors.forename: E
authors.initials: E
authors.lastname: Brydl
authors.forename: L
authors.initials: L
authors.lastname: Jakab
authors.forename: S
authors.initials: S
authors.lastname: Tuboly
authors.forename: E
authors.initials: E
authors.lastname: Túry
mesh_terms: D000821:Animal Feed; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001522:Behavior, Animal / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002412:Cations / Q000097:blood; D003875:Drug Eruptions / Q000473:pathology / Q000662:veterinary*; D002149:Energy Intake / Q000187:drug effects; D004734:Energy Metabolism / Q000187:drug effects; D011506:Proteins / Q000378:metabolism; D013552:Swine / Q000097:blood / Q000502:physiology*; D013553:Swine Diseases / Q000139:chemically induced* / Q000473:pathology; D013605:T-2 Toxin / Q000008:administration & dosage / Q000633:toxicity*; D015430:Weight Gain / Q000187:drug effects
chemical_list: D002412:Cations; D011506:Proteins; D001219:Aspartate Aminotransferases; D013605:T-2 Toxin