Diverse transposable elements are mobilized in hybrid dysgenesis in Drosophila virilis.
We describe a system of hybrid dysgenesis in Drosophila virilis in which at least four unrelated transposable elements are all mobilized following a dysgenic cross. The data are largely consistent with the superposition of at least three different systems of hybrid dysgenesis, each repressing a different transposable element, which break down following the hybrid cross, possibly because they share a common pathway in the host. The data are also consistent with a mechanism in which mobilization of a single element triggers that of others, perhaps through chromosome breakage. The mobilization of multiple, unrelated elements in hybrid dysgenesis is reminiscent of McClintock's evidence [McClintock, B. (1955) Brookhaven Symp. Biol. 8, 58-74] for simultaneous mobilization of different transposable elements in maize.
Petrov
D A
DA
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
Schutzman
J L
JL
Hartl
D L
DL
Lozovskaya
E R
ER
D000595:Amino Acid Sequence; D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D003433:Crosses, Genetic; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004251:DNA Transposable Elements; D004330:Drosophila / Q000235:genetics*; D005260:Female; D015698:Genomic Library; D006059:Gonadal Dysgenesis; D008297:Male; D008969:Molecular Sequence Data; D009154:Mutation; D016366:Open Reading Frames; D012091:Repetitive Sequences, Nucleic Acid; D018626:Retroelements; D014960:X Chromosome; D003313:Zea mays / Q000235:genetics
D004251:DNA Transposable Elements; D018626:Retroelements; D004247:DNA