[Anti-lipid peroxidation effects of sini decoction and its components on ischemic myocardium and the dose- and time-effects].
The complete Sini Decoction can significantly reduce the content of MDA in ischemic myocardium. Single ingredients of the decoction, such as Radix Aconoti Praeparata or Radix Glycyrrhizae, except Rhizoma Zingiberis, also have similar effect but inferior to that of the complete decoction. Under the present conditions of experiment, anti-lipid peroxidation of Sini Decoction is significant at doses ranging from 0.05 to 0.2ml/20g administered for 2-7 days at 0.1ml/(20g.d).
Wu
W
W
Sun Yat-sen University of Medical Sciences, Guangzhou.
Hou
C
C
Luo
H
H
Jin
W
W
Luo
C
C
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051379:Mice; D017202:Myocardial Ischemia / Q000378:metabolism*; D013997:Time Factors
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal