title: Radiation-induced vesicosacral fistula: treatment with continent urinary diversion.
abstract: This is the first Case Report of a vesicosacral fistula related to prior radiation therapy. This patient developed recurrent adenosquamous carcinoma of the cervix 1 year after radical hysterectomy. She received 5000 cGy to the whole pelvis and a 1500-cGy boost to the area of recurrence in the right pelvic sidewall. The patient had significant toxicity with recurrent pelvic fistula formation ultimately requiring an end sigmoid colostomy. In addition, the patient required urethral catheterization due to urinary incontinence secondary to a hypertonic bladder. Approximately 14 years after radiation therapy the patient developed a vesicosacral fistula. With a nonfunctional bladder, the decision was made to proceed with a continent urinary diversion procedure. Despite a prior ileocecal resection due to radiation injury, a Miami pouch reservoir was created. Postoperatively, the patient remained continent using intermittent catheterization of the pouch.
authors.affiliation: Section on Gynecologic Oncology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina 27157, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Lentz
authors.forename: H D
authors.initials: HD
authors.lastname: Homesley
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D005260:Female; D005402:Fistula / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D011832:Radiation Injuries / Q000209:etiology* / Q000601:surgery; D012447:Sacrum / Q000601:surgery; D013122:Spinal Diseases / Q000209:etiology / Q000601:surgery; D001747:Urinary Bladder Fistula / Q000209:etiology / Q000601:surgery; D014547:Urinary Diversion; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*