title: 3 beta-aminospirosolane steroidal alkaloids from Solanum triste.
abstract: The alkaloid fraction of the MeOH extract of the aerial parts of Solanum triste afforded the new steroidal alkaloid, (22R,25R)-3 beta-amino-5-spirosolene [2], and its previously synthesized dihydro derivative, (22R,24R)-3 beta-amino-5 alpha-spirosolane [3], which is reported here for the first time as a natural product. The structures were elucidated by spectral techniques including 1H-nmr, 13C-nmr, and 1H-1H COSY, HMQC, HMBC, and NOESY nmr experiments.
authors.affiliation: Department of Chemistry, University of the West Indies, Trinidad.
authors.forename: A
authors.initials: A
authors.lastname: Maxwell
authors.forename: M
authors.initials: M
authors.lastname: Seepersaud
authors.forename: R
authors.initials: R
authors.lastname: Pingal
authors.forename: D R
authors.initials: DR
authors.lastname: Mootoo
authors.forename: W F
authors.initials: WF
authors.lastname: Reynolds
mesh_terms: D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D010840:Phytosterols / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D012991:Solanaceous Alkaloids / Q000737:chemistry*
chemical_list: C094792:3-amino-5-spirosolene; C094793:3-aminospirosolane; D010840:Phytosterols; D012991:Solanaceous Alkaloids