[Cerebral blood flow and post-TIA depression].
OBJECTIVE
This study tries to evaluate the hypothesis of an association between severity of post-stroke depression and reduced cerebral blood flow (SPECT Xenon-133).


METHODS
37 patients in the fourth week of post-stroke evolution with RDS criteria of major depression (N = 20) and non-depressed patients (N = 17) were compared in regard to following parameters: values of cerebral blood flow (SPECT Xenon-133), localization of brain lesion (CT Scanner) and quantitative measurement of mood (HDRS, MARDS, BDI), functional ability (Barthel, Karnofsky), cognitive function (MMSE, WPT) and neurological function (Orgogozo's Scale).


RESULTS
Post-stroke major depression is more frequent (NS) in left and anterior lesions. We also demonstrated a significant association between total brain hypoperfusion and 1) severity of post-stroke depression, 2) severity of neurologic and functional impairments.


CONCLUSIONS
these results suggest a relationship between mood and cerebral perfusion following stroke.
González-Torrecillas
J L
JL
Centro Neuropsiquiátrico, Nuestra Señora del Carmen, Zaragoza, España.
Staner
L
L
Mendlewicz
J
J
D000328:Adult; D000368:Aged; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology*; D003866:Depressive Disorder / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012720:Severity of Illness Index; D015899:Tomography, Emission-Computed, Single-Photon
Flujo sanguíneo cerebral y depresión post-ACV.