Murine complement reduces infectivity of Plasmodium yoelii to mosquitoes.
The alternative pathway of complement in the mouse serum significantly reduced, but did not eliminate, the infectivity of Plasmodium yoelii to Anopheles stephensi. The reduction of the infectivity is mainly due to the inability of the zygote to transform into the ookinete in the mosquito midgut.
Tsuboi
T
T
Department of Parasitology, Ehime University School of Medicine, Japan.
Cao
Y M
YM
Torii
M
M
Hitsumoto
Y
Y
Kanbara
H
H
D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D003170:Complement Pathway, Alternative; D003165:Complement System Proteins / Q000502:physiology*; D005260:Female; D006801:Humans; D051379:Mice; D008811:Mice, Inbred DBA; D010967:Plasmodium yoelii / Q000502:physiology*
D003165:Complement System Proteins