Tc-99m phytate bone marrow scintigraphy showing multiple areas of focal hyperactivity in a patient with lung cancer. A case report.
Focal hyperactivity indicative of metastases is a rare finding in bone marrow imaging. In a lung cancer patient with multiple bony metastases, the Tc-99m phytate bone marrow imaging revealed multiple focal areas of increased radioactivity corresponding to the bone scan findings. The findings presented are consistent with a previous animal study, which found that phytate distribution was similar to that of diphosphonate in the skeletal system of rats and rabbits. The authors conclude that Tc-99m phytate should not be used as a bone marrow imaging agent. Further studies of Tc-99m phytate bone marrow scintigraphy on human beings are under way.
Chang
C P
CP
Department of Nuclear Medicine, Taipei Veterans General Hospital, Taiwan.
Chu
L S
LS
Liu
R S
RS
Yu
S M
SM
Yeh
S H
SH
D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000556:secondary; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging
D015609:Organotechnetium Compounds; C026177:technetium phytate; D010833:Phytic Acid