title: Treatment and diagnostic subtype in facial affect recognition in schizophrenia.
abstract: Patients with schizophrenia have been described as having deficits in the ability to recognize facial expressions of emotion. We report the results of a study on the effects of global psychopathology, positive and negative symptoms, diagnostic subtype, and antipsychotic medications, on the ability of subjects with schizophrenia to recognize facial affect. Eighteen SCID diagnosed patients with schizophrenia and ten matched controls were evaluated at a drug-free baseline for ability to identify facial expression expressed in a standardized series of photographs, with concurrent measures of global psychopathology, and positive and negative symptoms. At baseline patients were impaired in affect recognition relative to the normals, and impairment was not related to measures of psychopathology or positive or negative symptoms. Performance did not improve with antipsychotic treatment, and patients with paranoid schizophrenia had significantly better affect recognition abilities than non-paranoid patients.
authors.affiliation: Department of Psychiatry, University of Arizona School of Medicine, Tucson VAMC 85623, USA.
authors.forename: S F
authors.initials: SF
authors.lastname: Lewis
authors.forename: D L
authors.initials: DL
authors.lastname: Garver
mesh_terms: D000328:Adult; D000339:Affect; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D005149:Facial Expression; D006801:Humans; D008875:Middle Aged; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D013647:Task Performance and Analysis; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents