Action of testosterone on the estradiol-induced feminization of the male chick embryo.
The early treatment of male chick embryos with estradiol induces the feminization of their sex tract, i.e. both their gonads and müllerian tract exhibit female features. The additional treatment of estrogenized male embryos with testosterone propionate antagonizes the effects of estradiol on both gonads and müllerian ducts. Our data give further support to the view that testosterone and estrogens act respectively as agonist and antagonist modulators of the secretion of the anti-müllerian hormone.
Faucounau
N
N
Faculté de Médecine Paul Broca, Laboratoire d'Histo-Embryologie, Université Bordeaux II, France.
Ichas
F
F
Stoll
R
R
Maraud
R
R
D013734:Androgen-Insensitivity Syndrome / Q000139:chemically induced; D000818:Animals; D002642:Chick Embryo; D004958:Estradiol / Q000494:pharmacology*; D004965:Estrogen Antagonists / Q000494:pharmacology; D005262:Feminization / Q000139:chemically induced*; D008297:Male; D009095:Mullerian Ducts / Q000187:drug effects / Q000196:embryology*; D012733:Sex Differentiation; D013737:Testis / Q000187:drug effects / Q000196:embryology*; D013739:Testosterone / Q000494:pharmacology*
D004965:Estrogen Antagonists; D013739:Testosterone; D004958:Estradiol