title: Dynamic characteristics of prosthetic heart valves.
abstract: The relation between flow rate (Q) and transvalvular pressure-drop (DP) is of fundamental importance for a prosthetic heart valve tested in steady flow conditions. The Q-DP plot can thus be called the static characteristic of the valve. While in pulsatile flow, with time (t) as a parameter, the instantaneous Q(t)-DP(t) relation can also be obtained. The Q-DP relation forms a phase graph on an X-Y plane during a whole cardiac cycle, and can be regarded as the dynamic characteristic, which to our knowledge has never been systematically explored before. With in vitro experiment the Q(t)-DP(t) relations are presented for five different aortic valves. Properly modelling the characteristics of heart valves is a key link in modelling the interactions between the ventricle and arterial system. Treatments for valves, such as diode analogue and orifice area assumption governed by the Gorlin formula, are found unsatisfactory. A simple one-dimensional flow equation is used to further examine the Q-DP graph, and both the dynamic resistance characteristic and the dynamic flow characteristic can be obtained. It is found that the dynamic characteristic differs from the static one not only in the inertance effect but also in the transient process, which can be quite energy-consuming and therefore important. Geometric relations of these phase graphs with the transvalvular power loss are discussed. The method of dynamic characteristics provides a new way to evaluate the performance of a tested valve.
authors.affiliation: Department of Anatomy, Shanghai Medical University, People's Republic of China.
authors.forename: J
authors.initials: J
authors.lastname: She
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.forename: L
authors.initials: L
authors.lastname: Huan
authors.forename: Y
authors.initials: Y
authors.lastname: Yu
mesh_terms: D001698:Biomedical Engineering; D001794:Blood Pressure; D006350:Heart Valve Prosthesis; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D012039:Regional Blood Flow