title: Laparoscopic splenectomy. The initial experience at University of California, San Francisco.
abstract: OBJECTIVE
  To evaluate the outcomes of patients undergoing laparoscopic splenectomy (LS) at a single institution.
  
  
  METHODS
  Case control.
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  The medical records of the initial 25 consecutive patients who underwent LS at a single institution were reviewed. For comparison, a control group of 25 patients undergoing open splenectomy (OS) matched for age, diagnosis, and splenic weight were also reviewed.
  
  
  METHODS
  Data regarding operative time, blood loss, pathologic findings, complications, postoperative hospital stay, ileus duration, preoperative and postoperative hematocrit and platelet counts, blood and platelet transfusions, and hospital costs were collected.
  
  
  RESULTS
  Twenty-five patients underwent attempted LS. Four procedures (16%) were converted to OS. Operative time averaged 3.3 +/- 0.2 hours for LS and 2.6 +/- 0.1 hours for OS (P = .001). In the LS group, a regular diet was tolerated 2.1 +/- 0.3 days after surgery (P < .001), and mean postoperative hospital stay was 5.1 +/- 0.6 days (P = .037), compared with 4.3 +/- 0.3 and 6.7 +/- 0.5 days, respectively, in the OS group. No differences were observed in blood loss, complication rate, transfusion requirement, or hospital cost.
  
  
  CONCLUSIONS
  Compared with OS, LS requires more operative time, is comparable in blood loss, transfusion requirement, complication rate, and cost, and appears to be superior in terms of return of bowel function and hospital stay.
authors.affiliation: Department of Surgery, University of California, San Francisco, USA.
authors.forename: L F
authors.initials: LF
authors.lastname: Yee
authors.forename: S H
authors.initials: SH
authors.lastname: Carvajal
authors.forename: A A
authors.initials: AA
authors.lastname: de Lorimier
authors.forename: S J
authors.initials: SJ
authors.lastname: Mulvihill
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D017721:Hospital Costs; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000191:economics / Q000379:methods*; D007902:Length of Stay; D008297:Male; D013156:Splenectomy / Q000009:adverse effects / Q000191:economics / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome