Myxoma of the conjunctiva: a case report and a review of the literature.
A rare case of conjunctival myxoma is reported. A painless tumor was noted in the left bulbar conjunctiva of an 80-year-old woman. The extirpated tumor, 12 x 10 mm, was hypocellular and composed of spindle-shaped or stellate tumor cells. The tumor stroma showed extensive myxomatous changes. Alcian blue stain with hyaluronidase digestion revealed that the matrix contained rich amounts of hyaluronidase-sensitive acid mucopolysaccharides. Immunohistochemically, the tumor cells were positive for vimentin and alpha-smooth muscle actin, suggesting a fibroblastic or myofibroblastic cell phenotype. A review of the literature revealed the rare incidence and invariable benign behavior of conjunctival myxoma.
Horie
Y
Y
Department of Clinical Laboratory Medicine, Faculty of Medicine, Tottori University, Japan.
Ikawa
S
S
Okamoto
I
I
Nagata
M
M
Tamai
A
A
D000199:Actins / Q000032:analysis; D000368:Aged; D000369:Aged, 80 and over; D003230:Conjunctival Neoplasms / Q000737:chemistry / Q000473:pathology*; D005260:Female; D006025:Glycosaminoglycans / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D009232:Myxoma / Q000737:chemistry / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D000199:Actins; D006025:Glycosaminoglycans; D014746:Vimentin