title: [Non-invasive monitoring of cerebral oxygenation by NIR spectrophotometry (clinical trial)].
abstract: A Shimazu OM-100A near infrared spectrophotometer was used to monitor the cerebral oxygenated hemoglobin (Oxy-Hb), deoxygenated hemoglobin (Deoxy-Hb) and total hemoglobin (Total-Hb) in 3 patients with a) massive hemorrhage, b) ruptured aneurysm in the abdominal aorta, or c) hypercapnia. The hematocrit value of the patient with massive hemorrhage decreased rapidly to 18 %; the Total-Hb and Oxy-Hb also decreased significantly. Red blood cell transfusion raised the Oxy-Hb level, indicating an improvement in cerebral oxygenation. In the patient with a ruptured aneurysm, changes in blood flow brought about by clamping or declamping of the abdominal aorta were immediately reflected by corresponding changes in Total-Hb and Oxy-Hb. Oxy-Hb increased significantly and correlated well with the PETCO2 value in the patient with hypercapnia. Thus, NIR spectrophotometry is a useful non-invasive tool which can monitor metabolic and hemodynamic changes in the brain in various pathological conditions.
authors.affiliation: Department of Anesthesiology and Reanimatology, Kagoshima University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Kakihana
authors.forename: T
authors.initials: T
authors.lastname: Arimura
authors.forename: T
authors.initials: T
authors.lastname: Oda
authors.forename: N
authors.initials: N
authors.lastname: Yoshimura
mesh_terms: D000328:Adult; D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000378:metabolism / Q000601:surgery; D001921:Brain / Q000378:metabolism*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D010108:Oxyhemoglobins / Q000378:metabolism*; D013055:Spectrophotometry, Infrared
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins