title: Surgery for exocrine pancreatic cancer--who are the 5- and 10-year survivors?
abstract: 38 of 306 patients survived beyond 5 years after resection of an exocrine pancreatic carcinoma during a period from 1971 to 1993. Amongst the long-term survivors there were 12 patients with ductal, 22 with ampullary, 3 with distal bile duct and 1 with duodenal cancer. An active operative strategy was employed in order to resect the tumor whenever this was surgically possible. In a a retrospective analysis we have identified prognostic factors influencing long-term survival. The long-term prognosis was largely dependent on the tumor entity. Ampullary carcinomas had a significant advantage in terms of long-term survival over all other tumor entities. Other prognostic factors associated with long term survival were curative tumor resection, absence of lymphatic and distant metastases and a low tumor malignancy.
authors.affiliation: Clinic for Abdominal and Transplantation Surgery, Hanover Medical School, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Klempnauer
authors.forename: G J
authors.initials: GJ
authors.lastname: Ridder
authors.forename: H
authors.initials: H
authors.lastname: Bektas
authors.forename: R
authors.initials: R
authors.lastname: Pichlmayr
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000401:mortality* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis