"C" trigonocephaly syndrome: report of a child with agenesis of the corpus callosum and tetralogy of Fallot, and review.
We report on a new case of the Opitz "C" trigonocephaly syndrome. Our patient had agenesis of the corpus callosum, an anomaly seen only twice previously, and tetralogy of Fallot, described only once before. A review shows that a combination of conotruncal heart defects and midline brain anomalies characterizes patients with this entity.
Glickstein
J
J
Department of Pediatrics, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York 10467, USA.
Karasik
J
J
Caride
D G
DG
Marion
R W
RW
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000235:genetics; D061085:Agenesis of Corpus Callosum; D003398:Craniosynostoses / Q000175:diagnosis* / Q000235:genetics; D017809:Fatal Outcome; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007223:Infant; D013577:Syndrome; D013771:Tetralogy of Fallot / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D014056:Tomography, X-Ray