title: Measurement of epidermal moisture content by magnetic resonance imaging: assessment of a hydration cream.
abstract: The moisture content of the epidermis was measured by magnetic resonance imaging (MRI), using transverse relaxation time. The spatial resolution was 86 microns, allowing a quantitative, accurate and localized determination of variations in epidermal hydration. The wrists of 15 volunteers were studied before and after application of a hydration cream. Results showed an increase of 15% of epidermal T2 after application of the cream. Moisture content curves varied according to different degrees of skin dryness. This study demonstrates that MRI is a useful tool in evaluation of epidermal hydration.
authors.affiliation: Laboratoire de Biophysique Cellulaire et Résonance Magnétique Nucléaire, Faculté de Médecine, Tours, France.
authors.forename: F
authors.initials: F
authors.lastname: Franconi
authors.forename: S
authors.initials: S
authors.lastname: Akoka
authors.forename: J
authors.initials: J
authors.lastname: Guesnet
authors.forename: J M
authors.initials: JM
authors.lastname: Baret
authors.forename: D
authors.initials: D
authors.lastname: Dersigny
authors.forename: B
authors.initials: B
authors.lastname: Breda
authors.forename: C
authors.initials: C
authors.lastname: Muller
authors.forename: P
authors.initials: P
authors.lastname: Beau
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D001834:Body Water; D003358:Cosmetics / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D012867:Skin / Q000187:drug effects; D014953:Wrist
chemical_list: D003358:Cosmetics