title: Inosine 5'-monophosphate dehydrogenase as a chemotherapeutic target.
authors.affiliation: Cancer Research Department, Zeneca Pharmaceuticals, Alderley Park, Macclesfield, England.
authors.forename: T J
authors.initials: TJ
authors.lastname: Franklin
authors.forename: G
authors.initials: G
authors.lastname: Edwards
authors.forename: P
authors.initials: P
authors.lastname: Hedge
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology / Q000627:therapeutic use; D001419:Bacteria / Q000201:enzymology; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D009705:Nucleosides / Q000494:pharmacology* / Q000627:therapeutic use; D010802:Phylogeny
chemical_list: D000964:Antimetabolites, Antineoplastic; D004791:Enzyme Inhibitors; D009705:Nucleosides; D007168:IMP Dehydrogenase