Comparison of adenosine 5'-monophosphate and methacholine for the differentiation of asthma from chronic airway diseases with the use of the auscultative method in very young children.
Methacholine and adenosine 5'-monophosphate bronchial challenges were performed in 54 young children--39 with asthma and 15 with other chronic airway diseases (CADs), with the use of the auscultative method. Children with asthma were sensitive to both methacholine and adenosine; children with CAD responded only to methacholine. We conclude that bronchial challenge with adenosine can help differentiate asthma from CAD in young children.
Avital
A
A
Institute of Pulmonology, Hadassah University Hospital, Jerusalem, Israel.
Picard
E
E
Uwyyed
K
K
Springer
C
C
D000249:Adenosine Monophosphate; D001249:Asthma / Q000175:diagnosis*; D001314:Auscultation / Q000379:methods* / Q000706:statistics & numerical data; D001985:Bronchial Provocation Tests / Q000379:methods / Q000706:statistics & numerical data; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004311:Double-Blind Method; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis*; D016210:Methacholine Chloride; D012680:Sensitivity and Specificity
D016210:Methacholine Chloride; D000249:Adenosine Monophosphate