[Mechanisms of protective immune response in models of Marburg fever in monkeys].
The parameters of nonspecific immunity (interferon, tumor necrosis factor, natural killers), of spontaneous and mitogen-induced lymphocyte proliferation, of specific immunity (antibodies to Marburg virus, antigen-stimulated proliferation) were found to change in the course of experimental Marburg fever in immune and intact animals. The named factors were shown to influence the course of the disease; their role in the lethal outcome of the infection was demonstrated.
Ignat'ev
G M
GM
Strel'tsova
M A
MA
Agafonov
A P
AP
Kashentseva
E A
EA
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D000956:Antigens, Viral / Q000276:immunology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D007111:Immunity, Cellular; D008251:Macaca; D008379:Marburg Virus Disease / Q000276:immunology*; D029024:Marburgvirus / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral
Mekhanizmy protektivnogo immunogo otveta pri modelirovanii likhoradki Marburg na obez'ianakh.