title: Microsatellite instability in human prostate cancer.
abstract: Microsatellite instability (MSI) was examined at 36 loci, and found in 9 (43%) of the 21 prostatic cancers. A loss of heterozygosity had occurred in five cases (24%). MSI did not correlate with clinical stage, but might play a role in the development of a subset of prostate cancers.
authors.affiliation: Department of Pathology, Mie University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Imai
authors.forename: T
authors.initials: T
authors.lastname: Shiraishi
authors.forename: J
authors.initials: J
authors.lastname: Shimazaki
authors.forename: T
authors.initials: T
authors.lastname: Kotake
authors.forename: R
authors.initials: R
authors.lastname: Yatani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000483:Alleles; D004273:DNA, Neoplasm / Q000235:genetics*; D004276:DNA, Satellite / Q000235:genetics*; D004355:Drug Stability; D017353:Gene Deletion; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000235:genetics*
chemical_list: D004273:DNA, Neoplasm; D004276:DNA, Satellite