title: Isolation and characterization of mutations in the mouse APRT gene that encode functional enzymes with resistance to toxic adenine analogs.
authors.affiliation: Department of Microbiology and Immunology, University of Kentucky, Lexington 40536, USA.
authors.forename: N H
authors.initials: NH
authors.lastname: Khattar
authors.forename: C D
authors.initials: CD
authors.lastname: Jennings
authors.forename: K A
authors.initials: KA
authors.lastname: Walker
authors.forename: M S
authors.initials: MS
authors.lastname: Turker
mesh_terms: D015075:2-Aminopurine / Q000031:analogs & derivatives* / Q000633:toxicity; D000225:Adenine / Q000031:analogs & derivatives* / Q000633:toxicity*; D000228:Adenine Phosphoribosyltransferase / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D000818:Animals; D018236:Carcinoma, Embryonal; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D016296:Mutagenesis; D014407:Tumor Cells, Cultured; D014466:Ultraviolet Rays
chemical_list: D015075:2-Aminopurine; C007300:2,6-diaminopurine; D005020:Ethyl Methanesulfonate; D000228:Adenine Phosphoribosyltransferase; D000225:Adenine