title: A novel human papillomavirus sequence based on L1 general primers.
abstract: Over 65 human papillomaviruses (HPVs) have been identified. The majority have been isolated on the basis of cloning systems in bacteria. Recently, general consensus or degenerate primers from the L1 region have been used in PCR to identify novel genotypes. In this fashion, we employed general primers in the L1 region followed by DNA sequencing to identify a novel HPV sequence in association with esophageal squamous cell carcinoma.
authors.affiliation: Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
authors.forename: K
authors.initials: K
authors.lastname: Togawa
authors.forename: A K
authors.initials: AK
authors.lastname: Rustgi
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002294:Carcinoma, Squamous Cell / Q000235:genetics; D004938:Esophageal Neoplasms / Q000235:genetics; D005814:Genes, Viral; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D009856:Oncogene Proteins, Viral / Q000235:genetics*; D027383:Papillomaviridae / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
chemical_list: D009856:Oncogene Proteins, Viral