title: [Value of the AMBER system in interstitial lung changes].
abstract: OBJECTIVE
  To evaluate the diagnostic value of the AMBER technique in the diagnosis of interstitial lung disease.
  
  
  METHODS
  A prospective comparison of conventional and AMBER chest radiographs of 52 patients was performed using HR-CT as a gold standard on the same day. ROC analysis based on the results of 5 observers was carried out to quantify the diagnostic value of both chest radiograph techniques.
  
  
  RESULTS
  The ROC area for the AMBER system (0.860) showed statistically significant superiority in comparison to the conventional technique (0.828). This was mainly due to the better sensitivity of the AMBER system (65.3%) compared to the conventional chest radiographs (39.8%) within the lung regions superimposed by the diaphragm or the mediastinum. No difference between both methods was observed within the lung regions without superimposion.
  
  
  CONCLUSIONS
  AMBER technique improved conventional chest radiography in the diagnosis of interstitial lung disease due to superiority in the superimposed lung regions.
authors.affiliation: Radiologische Universitätsklinik, Eberhard-Karls-Universität Tübingen.
authors.forename: F
authors.initials: F
authors.lastname: Dammann
authors.forename: R
authors.initials: R
authors.lastname: Sokiranski
authors.forename: C
authors.initials: C
authors.lastname: Schäfer
authors.forename: H J
authors.initials: HJ
authors.lastname: Brambs
authors.forename: C D
authors.initials: CD
authors.lastname: Claussen
mesh_terms: D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012372:ROC Curve; D011856:Radiographic Image Enhancement; D013902:Radiography, Thoracic / Q000379:methods*; D012680:Sensitivity and Specificity; D014963:X-Ray Intensifying Screens
vernacular_title: Wertigkeit des AMBER-Systems bei interstitiellen Lungenveränderungen.