title: [Disruption of the permeability of blood-tissue barriers in mechanisms of primary reaction to irradiation].
abstract: This study is dedicated to an investigation of the role and importance of postradiation disturbances in the permeability of the vascular-tissue barriers (hematoophtalmic, hematolabyrinth, and hematoliquor) in the origination of neuroreflectory expressions during the early period of acute radiation sickness. The results of experimental studies suggest a correlation between disturbances in the permeability of the vascular-tissue barriers and clinical expressions of the primary postradiation response. The reduction of postradiation disturbances in the permeability of the vascular-tissue barriers by the agents stabilizing the membrane permeability, e.g., the antioxidant alpha-tocopherol, leads to a decreased primary postradiation response.
authors.forename: N I
authors.initials: NI
authors.lastname: Arlashchenko
mesh_terms: D000208:Acute Disease; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use; D002199:Capillary Permeability / Q000187:drug effects / Q000528:radiation effects*; D011817:Rabbits; D011833:Radiation Injuries, Experimental / Q000503:physiopathology* / Q000517:prevention & control; D014810:Vitamin E / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D014810:Vitamin E
vernacular_title: Narusheniia pronitsaemosti sosudistotkanevykh bar'erov v mekhanizmakh pervichnoĭ reaktsii na obluchenie.