title: Nicotinamide and diabetes prevention.
abstract: Individuals at high risk of developing insulin-dependent diabetes mellitus can now be identified by immunologic testing. This ability to predict future cases of IDDM raises the possibility of intervention to prevent the disease. An intervention study in New Zealand using nicotinamide treatment showed a 50% reduction in the development of IDDM in a 5-year period.
authors.affiliation: University Hospital, London, Ontario, Canada.
authors.forename: M T
authors.initials: MT
authors.lastname: Behme
mesh_terms: D002648:Child; D002986:Clinical Trials as Topic; D003922:Diabetes Mellitus, Type 1 / Q000517:prevention & control*; D006801:Humans; D009520:New Zealand; D009536:Niacinamide / Q000627:therapeutic use*; D012307:Risk Factors
chemical_list: D009536:Niacinamide