title: Pseudomonas syringae pv. syringae phytotoxins reversibly inhibit the plasma membrane H(+)-ATPase and disrupt unilamellar liposomes.
abstract: The Pseudomonas syringae pv. syringae phytotoxins syringomycin-E and syringopeptins 22-A and 25-A reversibly and noncompetitively inhibit purified H(+)-ATPase solubilized from plasma membrane of maize roots. Moreover, they increase the passive permeability to protons in phosphatidylcholine/phosphatidylethanolamine liposomes. Both effects are more pronounced with syringopeptins than with syringomycin-E. Activity on phospholipid bilayers is detectable at phytotoxin concentrations not affecting H(+)-ATPase activity.
authors.affiliation: Dipartimento di Biologia, Università di Roma, Tor Vergata, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Camoni
authors.forename: D
authors.initials: D
authors.lastname: Di Giorgio
authors.forename: M
authors.initials: M
authors.lastname: Marra
authors.forename: P
authors.initials: P
authors.lastname: Aducci
authors.forename: A
authors.initials: A
authors.lastname: Ballio
mesh_terms: D001427:Bacterial Toxins / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D008081:Liposomes; D006180:Proton-Translocating ATPases / Q000037:antagonists & inhibitors*; D011549:Pseudomonas / Q000737:chemistry*; D012995:Solubility; D003313:Zea mays / Q000166:cytology / Q000201:enzymology
chemical_list: D001427:Bacterial Toxins; D008081:Liposomes; D006180:Proton-Translocating ATPases