Adenosine deaminase (ADA) deficiency as the unexpected cause of CD4+ T-lymphocytopenia in two HIV-negative adult female siblings.
Fairbanks
L D
LD
Purine Research Laboratory, UMDS Guy's Hospital, London, GB.
Simmonds
H A
HA
Webster
A D
AD
Shovlin
C L
CL
Hughes
J M
JM
D000243:Adenosine Deaminase / Q000172:deficiency* / Q000235:genetics / Q000627:therapeutic use*; D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006580:Genetic Carrier Screening; D018023:HIV Seronegativity; D006720:Homozygote; D006801:Humans; D008297:Male; D010375:Pedigree; D016511:Severe Combined Immunodeficiency / Q000235:genetics / Q000276:immunology* / Q000628:therapy; D013997:Time Factors
D000243:Adenosine Deaminase; C051409:pegademase bovine