title: On doubling the signal in localised stimulated echo measurements.
abstract: Stimulated echo (STEAM) localisation yields up to 50% of the full magnetisation. It is shown that given the good magnetic field homogeneity now obtained in clinical MRS, and with a slight modification to the gradient pattern, the localised signal may be nearly doubled, although at the expense of introducing a frequency-dependent amplitude for peaks in the final spectrum. A two-step phase cycle is also required. The principle is demonstrated on a clinical MR system, and the relative merits of the sequence are discussed.
authors.affiliation: CRC Clinical Magnetic Resonance Research Group, Royal Marsden Hospital and Institute of Cancer Research, Surrey, England.
authors.forename: G S
authors.initials: GS
authors.lastname: Payne
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
mesh_terms: D009682:Magnetic Resonance Spectroscopy / Q000379:methods*