title: Serum protein polymorphisms (HP, TF-, GC- and PI subtypes) in two mountain communities of Sierra de Gredos (central Spain).
abstract: The genetic variation of four highly polymorphic serum proteins, haptoglobin (HP), transferrin (TF), group-specific component (GC) and alpha-1-antitrypsin (PI) was examined in two representative samples of the autochthonous populations living on either slope of Sierra de Gredos in central Spain. The genetic markers studied do not provide any evidence that the mountain chain has contributed to the maintenance of a genetic differentiation between the two populations. The allele frequency distributions in these Gredos samples are discussed in relation to the variability of these markers in the Iberian Peninsula populations.
authors.affiliation: Departamento de Biología Animal, Facultad de Biología, Universidad de Barcelona, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Moral
authors.forename: S
authors.initials: S
authors.lastname: Vives
authors.forename: R
authors.initials: R
authors.lastname: Fisac
authors.forename: J
authors.initials: J
authors.lastname: Martín
authors.forename: M S
authors.initials: MS
authors.lastname: Mesa
mesh_terms: D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006242:Haptoglobins / Q000235:genetics; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D013030:Spain; D014168:Transferrin / Q000235:genetics; D014809:Vitamin D-Binding Protein / Q000235:genetics; D000515:alpha 1-Antitrypsin / Q000235:genetics
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers; D006242:Haptoglobins; D014168:Transferrin; D014809:Vitamin D-Binding Protein; D000515:alpha 1-Antitrypsin