title: Surgical wound healing complicated by Aspergillus infection in a nonimmunocompromised host.
abstract: BACKGROUND
  An unusual complication of cutaneous surgery and its management is presented. Aspergillus flavus was identified from a nonhealing surgical wound of the ear undergoing cartilaginous necrosis in an immunocompetent host.
  
  
  OBJECTIVE
  We wish to alert clinicians that Aspergillus may infect surgical wounds of the ear causing significant morbidity.
  
  
  METHODS
  A healthy man underwent Mohs micrographic surgery for invasive Bowen's disease of the ear. Due to the size and location of the defect it was allowed to heal by secondary intent. The patient developed inflammation and subsequent destruction of the ear cartilage. Aspergillus was demonstrated by touch preps and cultured from swabs and tissue from the necrotic wound.
  
  
  RESULTS
  In spite of aggressive topical and oral antifungal therapy severe distortion of the pinna occurred, resulting in surgical removal of the upper two-thirds of the ear.
  
  
  CONCLUSIONS
  In the presence of cartilage necrosis following surgery on the ear, Aspergillus infection should be considered. Early aggressive management with surgical debridement, and topical and oral antifungal therapy may prevent destruction of the cartilage and a significant cosmetic defect.
authors.affiliation: Dermatology Service, Brooke Army Medical Center, Fort Sam Houston, Texas, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Anderson
authors.forename: M B
authors.initials: MB
authors.lastname: Giandoni
authors.forename: R A
authors.initials: RA
authors.lastname: Keller
authors.forename: W J
authors.initials: WJ
authors.lastname: Grabski
mesh_terms: D001228:Aspergillosis; D001231:Aspergillus flavus / Q000302:isolation & purification; D001913:Bowen's Disease / Q000601:surgery*; D004428:Ear Neoplasms / Q000601:surgery*; D004431:Ear, External / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery / Q000009:adverse effects; D010032:Otitis Externa / Q000382:microbiology*; D013530:Surgical Wound Infection / Q000382:microbiology*; D014945:Wound Healing