Ocular involvement in acute lymphoblastic leukaemia.
A six-year-old boy, a known case of acute lymphoblastic leukaemia (ALL) on remission since 1991 presented with leukocoria and poor vision of the left eye for two days' duration. Examination revealed endophthalmitis in the left eye with raised intraocular pressure. Anterior chamber paracentesis with vitreous biopsy confirmed a diagnosis of ocular involvement. Further investigation revealed that he also had bone marrow and central nervous system relapse. Clinical manifestation and treatment modalities of ocular involvement in leukaemia are discussed.
Tan
A K
AK
Department of Ophthalmology, Hospital Kuala Lumpur.
Azman
A
A
Hoe
T S
TS
Rohana
T
T
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D002490:Central Nervous System / Q000473:pathology; D002648:Child; D003131:Combined Modality Therapy; D009877:Endophthalmitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D005123:Eye / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D009364:Neoplasm Recurrence, Local; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*