title: Peritoneal papillary serous carcinoma: response to Taxol in platinum resistant disease.
abstract: A case of peritoneal papillary serous carcinoma which developed after total abdominal hysterectomy and bilateral salpingo-oophorectomy for a benign condition is presented. The patient was treated with platinum-based chemotherapy to which she initially responded, but then the tumor progressed. High dose paclitaxel (250 mg/m2) was given. The patient tolerated this treatment well, achieving a rapid partial response with good palliation of symptoms. Paclitaxel should be considered for patients with a platinum resistant peritoneal papillary serous carcinoma.
authors.affiliation: Ramathibodi Hospital, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Wilailak
authors.forename: A P
authors.initials: AP
authors.lastname: Kudelka
authors.forename: L R
authors.initials: LR
authors.lastname: Donner
authors.forename: E
authors.initials: E
authors.lastname: Silva
authors.forename: R
authors.initials: R
authors.lastname: Mante
authors.forename: J J
authors.initials: JJ
authors.lastname: Kavanagh
mesh_terms: D016190:Carboplatin / Q000627:therapeutic use; D018283:Cystadenocarcinoma, Papillary / Q000188:drug therapy*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D010534:Peritoneal Neoplasms / Q000188:drug therapy*
chemical_list: D016190:Carboplatin; D017239:Paclitaxel