Effect of toluene extraction on Biomer surface: I. ESCA, ATR/FTIR, contact angle analysis and biological properties.
Biomer is a poly(ether-urethane-urea) block copolymer widely used as biomedical devices. Extraction process of this polymer has purified its surface of low molecular weight polyurethane chains and Santowhite Powder additive. ESCA and ATR/FTIR have suggested a homogenization of the polymer by enrichment of the first layers with poly(aminomethacrylate) additive after extraction. Therefore, the surface of the extracted Biomer exhibits a different wettability and biological response. The treatment causes a significant decrease in fibronectin adsorption and induces a reduction in Staphylococcus aureus adhesion.
Nurdin
N
N
Group of Applied Physics, University of Geneva, Switzerland.
François
P
P
Magnani
A
A
Xanthopoulos
N
N
Mathieu
H J
HJ
Barbucci
R
R
Vaudaux
P
P
Descouts
P
P
D000327:Adsorption; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D001422:Bacterial Adhesion / Q000502:physiology*; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism* / Q000592:standards; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D004577:Electron Probe Microanalysis; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D008970:Molecular Weight; D011140:Polyurethanes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000378:metabolism; D014050:Toluene
D000975:Antioxidants; D001672:Biocompatible Materials; D005353:Fibronectins; D011140:Polyurethanes; D002084:Butylated Hydroxytoluene; D014050:Toluene; C031892:biomer; C030594:Santowhite powder