Benign familial pemphigus--premenstrual exacerbation suppressed by goserelin and oophorectomy.
We report the case of premenstrually exacerbated benign familial pemphigus which showed dramatic improvement with subcutaneous goserelin, a gonadotrophin-releasing hormone analogue. Total abdominal hysterectomy and bilateral salpingo-oophorectomy and oestrogen replacement therapy sustained the improvement.
James
M P
MP
Department of Dermatology, Royal Berkshire Hospital, Reading, UK.
Williams
R M
RM
D005260:Female; D017273:Goserelin / Q000627:therapeutic use*; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology*; D008875:Middle Aged; D010052:Ovariectomy; D016506:Pemphigus, Benign Familial / Q000628:therapy*; D010507:Periodicity
D017273:Goserelin