title: Langerhans cell histiocytosis involving the corpus callosum and cerebellum: gadolinium-enhanced MRI.
abstract: Langerhans cell histiocytosis is a systemic disorder consisting of abnormal histiocyte proliferation, in the form of focal deposits. Central nervous system involvement is most common in the hypothalamus, although other sites have been described, such as the cerebellum and the meninges. We present a case with presumed involvement of the corpus callosum and cerebellum, demonstrating gadolinium enhancement on MRI.
authors.affiliation: Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1088, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Strottmann
authors.forename: L E
authors.initials: LE
authors.lastname: Ginsberg
authors.forename: C
authors.initials: C
authors.lastname: Stanton
mesh_terms: D000293:Adolescent; D002531:Cerebellum / Q000473:pathology*; D003287:Contrast Media; D003337:Corpus Callosum / Q000473:pathology*; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA