title: Corpus callosotomy in children.
abstract: All of the reports of corpus callosotomy have been limited by their necessarily retrospective nature, lack of control groups, and failure to quantify seizure frequency and duration before and after the surgery. In addition, interpretation of results has been confusing by inconsistent selection criteria of patients, varying surgical procedures employed, and short duration of follow-up. Nevertheless, this procedure remains a last hope for many children with severe intractable epilepsy and unquestionably assists in the management of many such children. There is a need to evaluate this surgical procedure fully to optimize its utilization further.
authors.affiliation: Department of Neurosurgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Madsen
authors.forename: L
authors.initials: L
authors.lastname: Carmant
authors.forename: G L
authors.initials: GL
authors.lastname: Holmes
authors.forename: P M
authors.initials: PM
authors.lastname: Black
mesh_terms: D000293:Adolescent; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003337:Corpus Callosum / Q000601:surgery*; D004195:Disease Models, Animal; D004827:Epilepsy / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications; D016896:Treatment Outcome