title: Cholelithiasis in infants with Down syndrome: report of two cases.
abstract: Down syndrome is a chromosomal disorder most often observed in the newborn period. Various facial, limb and internal abnormalities are found in this disorder but cholelithiasis in infancy has been described in only one report. We report two infants with Down syndrome associated with cholelithiasis. Except for polycythemia and indirect hyperbilirubinemia, no hemolytic process or biochemical abnormalities were evident in both patients. We believe that the cause of gallstones in our cases may have been polycythemia in the newborn period. To our knowledge this is only the second report of gallstones in infancy in Down syndrome.
authors.affiliation: Karadeniz Technical University Faculty of Medicine, Department of Pediatrics, Trabzon, Turkey.
authors.forename: F M
authors.initials: FM
authors.lastname: Aynaci
authors.forename: E
authors.initials: E
authors.lastname: Erduran
authors.forename: H
authors.initials: H
authors.lastname: Mocan
authors.forename: A
authors.initials: A
authors.lastname: Okten
authors.forename: A O
authors.initials: AO
authors.lastname: Sarpkaya
mesh_terms: D002769:Cholelithiasis / Q000150:complications*; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011086:Polycythemia / Q000150:complications