title: [Stress and premature menopause].
abstract: By acting on the neuroendocrine system during the stress response, life events may greatly affect homeostasis and favor the appearance of disease. Here, we describe a relationship between stressful life events and premature ovarian failure. From a mechanistic point of view, we suggest an autoimmune origin for such premature ovarian failure on the basis of the role of cytokines in folliculogenesis and of their increased production during stressful life events.
authors.affiliation: Service de gynécologie-obstétrique, Hôpital Antoine-Béclère, Clamart, France.
authors.forename: H
authors.initials: H
authors.lastname: Letur-Könirsch
authors.forename: A
authors.initials: A
authors.lastname: Raoul-Duval
authors.forename: A
authors.initials: A
authors.lastname: Cabau
authors.forename: O
authors.initials: O
authors.lastname: Bomsel-Helmreich
authors.forename: W
authors.initials: W
authors.lastname: al Mufti
authors.forename: F
authors.initials: F
authors.lastname: Homo-Delarche
mesh_terms: D000328:Adult; D015551:Autoimmunity; D016207:Cytokines / Q000378:metabolism; D005260:Female; D006801:Humans; D008594:Menopause, Premature / Q000276:immunology / Q000378:metabolism*; D008875:Middle Aged; D013312:Stress, Physiological / Q000150:complications / Q000276:immunology / Q000378:metabolism*
chemical_list: D016207:Cytokines
vernacular_title: Stress et ménopause précoce.