The need for ventilatory support during bystander CPR.
OBJECTIVE
To compare CPR with chest compressions plus ventilatory support (CC+V) and chest compressions alone (CC).


METHODS
Prospective, randomized study.


METHODS
Research laboratory.


METHODS
After 2 minutes of ventricular fibrillation, 18 domestic swine (20 to 35 kg) were treated first with CC or CC+V for 10 minutes, then with standard advanced cardiac life support.


RESULTS
Hemodynamics, survival, and neurologic outcome were determined. All 8 swine subjected to CC+V and all 10 subjected to CC showed return of spontaneous circulation. One animal in each group died within 1 hour. Seven of 8 animals in the CC+V group survived for 24 and 48 hours, compared with 9 of 10 CC animals at 24 hours and 8 of 10 at 48 hours. All 48-hour survivors were neurologically normal.


CONCLUSIONS
In this experimental model of bystander CPR, we could not detect a difference in hemodynamics, 48-hour survival, or neurologic outcome when CPR was applied with and without ventilatory support.
Berg
R A
RA
Department of Pediatrics, College of Agriculture, University of Arizona, Tucson, USA.
Wilcoxson
D
D
Hilwig
R W
RW
Kern
K B
KB
Sanders
A B
AB
Otto
C W
CW
Eklund
D K
DK
Ewy
G A
GA
D000818:Animals; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D004195:Disease Models, Animal; D004632:Emergency Medical Services; D006336:Heart Massage / Q000379:methods*; D006439:Hemodynamics; D010100:Oxygen / Q000097:blood; D011897:Random Allocation; D016019:Survival Analysis; D013552:Swine; D013997:Time Factors; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
D010100:Oxygen