title: Are transrectal ultrasonically guided biopsies required for the accurate diagnosis of carcinoma of the prostate? Can digitally guided systematic biopsies offer an acceptable alternative?
abstract: OBJECTIVE
  To compare the diagnostic yield of ultrasonically guided and digitally guided systematic biopsies of the prostate.
  
  
  METHODS
  Fifty two patients with suspected but unproven carcinoma of the prostate underwent simultaneous transrectal ultrasonography (TRUS)-guided and digitally guided systematic biopsies of the prostate. A mean of 12 cores was obtained from each patient. On average more cores were obtained with TRUS guidance (mean 6.7) than with digital guidance (mean 5.3).
  
  
  RESULTS
  Cancer was detected in 19 patients and the diagnosis was made by both techniques in 16. Two patients had tumour detected only with TRUS guidance and one only with digital guidance. No complications occurred.
  
  
  CONCLUSIONS
  This study indicates that there is no significant difference between TRUS guidance and digital guidance to direct systematic biopsies of the prostate. The use of routine TRUS in screening programmes is now in doubt.
authors.affiliation: Department of Urology and Transplantation, University Hospital of Coimbra, Portugal.
authors.forename: A J
authors.initials: AJ
authors.lastname: Figueiredo
authors.forename: K
authors.initials: K
authors.lastname: Seeni
authors.forename: K M
authors.initials: KM
authors.lastname: Anson
authors.forename: A J
authors.initials: AJ
authors.lastname: Furtado
authors.forename: R A
authors.initials: RA
authors.lastname: Miller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010173:Palpation; D017060:Patient Satisfaction; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018084:Ultrasonography, Interventional