IL-1 beta-induced inhibition of beta-cell function is mediated through nitric oxide.
Xenos
E S
ES
Department of Surgery, University of Minnesota, Minneapolis 55455.
Stevens
R B
RB
Gores
P F
PF
Casanova
D
D
Farney
A C
AC
Sutherland
D E
DE
Platt
J L
JL
D000594:Amino Acid Oxidoreductases / Q000037:antagonists & inhibitors; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives* / Q000494:pharmacology; D002478:Cells, Cultured; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007375:Interleukin-1 / Q000494:pharmacology*; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase; D051381:Rats; D011917:Rats, Inbred Lew; D019323:omega-N-Methylarginine
D007328:Insulin; D007375:Interleukin-1; D019323:omega-N-Methylarginine; D009569:Nitric Oxide; D001120:Arginine; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases