Primary central nervous system lymphoma presenting as autonomic dysfunction.
We describe a patient with primary central nervous system lymphoma (PCNSL) who presented with symptoms of subacute onset of dysautonomia. Autonomic testing indicated a peripheral autonomic neuropathy while magnetic resonance imaging revealed brainstem involvement. We propose that this patient's autonomic dysfunction could be the result of a paraneoplastic syndrome and PCNSL should be considered in the differential diagnosis of dysautonomia.
Ficker
D M
DM
Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Hammack
J E
JE
D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000523:psychology; D001921:Brain / Q000473:pathology; D016543:Central Nervous System Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000523:psychology; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology; D008223:Lymphoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000523:psychology; D008279:Magnetic Resonance Imaging; D008297:Male; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging / Q000523:psychology; D010554:Personality Disorders / Q000209:etiology; D011877:Radionuclide Imaging