title: Adrenalectomy increases the glial fibrillary acidic immunoreactive-elements in the ventricular ependyma and adjacent neuropil of the rat third ventricle.
abstract: The reactions of bilateral adrenalectomy (14 days) on the rat glial fibrillary acidic-immunoreactive elements of the third ventricular ependyma and adjacent neuropil were analyzed using histological, immunohistochemical and morphometric methods. Bilateral adrenalectomy led to a drastic increase in the number of immunoreactive elements located in the neuropil adjacent to the third ventricle and the optic chiasm when compared to normal and sham-operated animals (p < 0.05). By contrast, the adrenalectomized animals receiving corticosterone showed the same characteristics and morphometric values as those found in normal and sham-operated animals. The results show that the participation of the adrenal gland in astroglial responses should be taken into account.
authors.affiliation: Department of Human Anatomy and Histology, Faculty of Medicine University of Salamanca, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Sánchez
authors.forename: G
authors.initials: G
authors.lastname: Hernández
authors.forename: M
authors.initials: M
authors.lastname: Rubio
authors.forename: M
authors.initials: M
authors.lastname: Santos
authors.forename: J
authors.initials: J
authors.lastname: Carretero
authors.forename: J
authors.initials: J
authors.lastname: Riesco
authors.forename: J
authors.initials: J
authors.lastname: Juanes
authors.forename: R
authors.initials: R
authors.lastname: Vázquez
mesh_terms: D000315:Adrenalectomy; D000818:Animals; D002552:Cerebral Ventricles / Q000166:cytology / Q000378:metabolism*; D004805:Ependyma / Q000166:cytology / Q000378:metabolism*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis / Q000096:biosynthesis*; D007150:Immunohistochemistry; D008297:Male; D009897:Optic Chiasm / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012016:Reference Values
chemical_list: D005904:Glial Fibrillary Acidic Protein