[Effects of cytokines on hippocampus in central nervous system].
Cytokines consist of a group of polypeptides, whose main functions are considered to be mediating the non-specific immune reaction and promoting differentiation, proliferation and growth of white blood cells. But according to recent studies, these cytokines such as interleukin-1 (IL-1), interleukin-2 (IL-2) and interleukin-6 (IL-6) and their receptors are also found in the central nervous system (CNS) and may play a role in modulating the physiological functions of neuronal and glial cells in CNS. In review, we summarize the representative studies concerning mainly the interleukins' effects on the hippocampus.
Yao
H
H
Institute of Basic Medical Science, Military Medical Academy of Science, Beijing.
Wang
F Z
FZ
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D016207:Cytokines / Q000494:pharmacology / Q000502:physiology*; D006624:Hippocampus / Q000378:metabolism / Q000502:physiology*; D007375:Interleukin-1 / Q000502:physiology; D007376:Interleukin-2 / Q000494:pharmacology / Q000502:physiology; D015850:Interleukin-6 / Q000502:physiology
D016207:Cytokines; D007375:Interleukin-1; D007376:Interleukin-2; D015850:Interleukin-6; D000109:Acetylcholine