title: Clinical features of neonatal seizures.
abstract: OBJECTIVE
  Identification of seizures in neonates is difficult. This study analyses the clinical features of seizures in a cohort of neonates.
  
  
  METHODS
  The clinical events of 41 neonates referred for investigation of suspected seizures were studied with prolonged video/electroencephalographic (EEG) telemetry.
  
  
  RESULTS
  Sixteen neonates had no seizures recorded; 25 had confirmed seizures, 13 with clinical correlates. Each neonate with electroclinical seizures had paroxysms of abnormal movements in stereotyped patterns. These patterns were consistently found to have electrical correlates. Focal clonic movements were seen most frequently. Multiple clinical features characterized the seizure repertoire in six neonates. In five neonates the clinical features became less evident during monitoring and these seizures were difficult to recognize. This change was associated with anticonvulsant administration in three cases.
  
  
  CONCLUSIONS
  Electroclinical seizures are characterized by abnormal paroxysmal stereotyped behaviour, often with multiple clinical features. Recommendations for the management of abnormal neonatal events are proposed.
authors.affiliation: Department of Neurology, Prince of Wales Children's Hospital, Randwick, New South Wales, Australia.
authors.forename: M W
authors.initials: MW
authors.lastname: O'Meara
authors.forename: A M
authors.initials: AM
authors.lastname: Bye
authors.forename: D
authors.initials: D
authors.lastname: Flanagan
mesh_terms: D015331:Cohort Studies; D003937:Diagnosis, Differential; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D012017:Referral and Consultation; D012640:Seizures / Q000145:classification / Q000151:congenital / Q000175:diagnosis* / Q000209:etiology; D013239:Stereotyped Behavior; D013686:Telemetry; D014743:Videotape Recording