No effect of maternal smoking in early pregnancy observed on chromosome aberrations in chorionic villus samples.
The effect of maternal smoking on first trimester chorionic villus samples (CVS) was studied by analysing the frequency of chromosome aberrations (CAs) among 20 non-smoking and 20 smoking mothers. The aberrations were classified as chromosome- and chromatid-type breaks and gaps. No statistically significant differences were found in the frequencies of CAs between non-smoking mothers (5.4% or 2.0% gaps excluded) and smoking mothers (3.5% or 1.0% gaps excluded).
Salonen
K
K
Department of Genetics, University of Turku, Finland.
Lähdetie
J
J
D000328:Adult; D000704:Analysis of Variance; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008423:Maternal Age; D008875:Middle Aged; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018566:Pregnancy, High-Risk; D012907:Smoking / Q000009:adverse effects*; D014327:Trophoblasts / Q000166:cytology