title: [Tuberculosis agent: biological characteristics and difficulties of microbiological diagnosis].
abstract: The natural occurrence of various mycobacteria and high morbidity rates due to mycobacteria-induced diseases among patients with immunodeficiency requires its precise diagnostic techniques. Numerous recent researches in tuberculosis microbiology discuss the impact of mycobacterial cell structural and functional changes on the occurrence of pulmonary disease. Mycobacteria isolated from the areas under special radiation control have been found to have a varying virulence. The spread of altered mycobacteria require not only microbiological, but also molecular genetic methods, which allows one gain a more insight into the nature of mycobacterial variability.
authors.forename: V I
authors.initials: VI
authors.lastname: Golishevskaia
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology; D006168:Guinea Pigs; D006801:Humans; D015269:Mycobacterium avium Complex / Q000502:physiology; D009163:Mycobacterium bovis / Q000502:physiology; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000472:pathogenicity / Q000502:physiology*; D013997:Time Factors; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000382:microbiology; D014774:Virulence
chemical_list: D000995:Antitubercular Agents
vernacular_title: Vozbuditel' tuberkuleza: biologicheskie osobennosti i trudnosti mikrobiologicheskoĭ diagnostiki.