title: No effect of maternal smoking in early pregnancy observed on chromosome aberrations in chorionic villus samples.
abstract: The effect of maternal smoking on first trimester chorionic villus samples (CVS) was studied by analysing the frequency of chromosome aberrations (CAs) among 20 non-smoking and 20 smoking mothers. The aberrations were classified as chromosome- and chromatid-type breaks and gaps. No statistically significant differences were found in the frequencies of CAs between non-smoking mothers (5.4% or 2.0% gaps excluded) and smoking mothers (3.5% or 1.0% gaps excluded).
authors.affiliation: Department of Genetics, University of Turku, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Salonen
authors.forename: J
authors.initials: J
authors.lastname: Lähdetie
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008423:Maternal Age; D008875:Middle Aged; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018566:Pregnancy, High-Risk; D012907:Smoking / Q000009:adverse effects*; D014327:Trophoblasts / Q000166:cytology