title: [Histoplasmosis, caused by Histoplasma capsulatum, and AIDS].
abstract: Histoplasma capsulatum histoplasmosis occurs frequently in endemic areas and with the AIDS outbreak, it appears as an opportunistic fungus involved in disseminated disease. We report the clinical, biological and treatment features of seven cases diagnosed in the CISIH of the Eastern part of Paris. Clinically, four patients were suffering from pulmonary symptoms, in three cases digestive disorders and in three cutaneous lesions. In all cases, the mycologic diagnosis was necessary. Amphotericin B and itraconazole were used as treatment for five patients (two died before the diagnosis was completed). Among these five subjects, four died (death was attributed to histoplasmosis in only one case). These observations emphasize the importance of this infection in HIV-infected patients coming from endemic areas.
authors.affiliation: Hôpital Saint-Antoine, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Levy
authors.forename: J L
authors.initials: JL
authors.lastname: Poirot
authors.forename: M
authors.initials: M
authors.lastname: Marteau-Miltgen
authors.forename: M C
authors.initials: MC
authors.lastname: Meyohas
authors.forename: P
authors.initials: P
authors.lastname: Roux
authors.forename: F
authors.initials: F
authors.lastname: Heyer
authors.forename: O
authors.initials: O
authors.lastname: Picard
authors.forename: L
authors.initials: L
authors.lastname: Blum
authors.forename: C
authors.initials: C
authors.lastname: Duvivier
authors.forename: D
authors.initials: D
authors.lastname: Binet
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000382:microbiology; D000666:Amphotericin B / Q000627:therapeutic use; D005260:Female; D006660:Histoplasmosis / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D017964:Itraconazole; D000666:Amphotericin B
vernacular_title: Histoplasmose à Histoplasma capsulatum et SIDA.