title: Olfactory performance during childhood. II. Developing a discrimination task for children.
abstract: OBJECTIVE
  (1) To create a match-to-sample odorant discrimination task (MODT) for children and adolescents; (2) to assess whether nonolfactory factors affect olfactory performance more on an identification task than on the MODT; (3) to evaluate subjects with olfactory dysfunction; and (4) to create age-appropriate sets of odorants for use in the MODT format to test children of different ages.
  
  
  METHODS
  We tested 75 normal children, aged 2 to 18 years, and 17 other subjects, aged 7 to 53 years, with known or suspected olfactory dysfunction, with the MODT. We compared the age trends in variability of scores on the MODT with those on an odorant identification task, using a weighted linear regression analysis.
  
  
  RESULTS
  The MODT was useful in children aged 5 years and older, but not generally in the 2- to 4-year-old children. There was an appreciable age trend in the variability of the scores on the identification task but not on the MODT. Mean MODT scores for subjects with suspected or known olfactory dysfunction were far below average. Finally, we created four sets of odorants that will likely be sensitive to age-specific changes in olfactory performance.
  
  
  CONCLUSIONS
  The MODT appears to be a suitable test instrument to assess olfaction in children aged 5 and older and is less likely to be influenced by nonolfactory factors than an identification task. According to our preliminary results, it is likely that the MODT will allow us to detect olfactory deficits in children of many ages.
authors.affiliation: Department of Pediatrics, State University of New York Health Science Center, Syracuse 13210, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Richman
authors.forename: P R
authors.initials: PR
authors.lastname: Sheehe
authors.forename: K
authors.initials: K
authors.lastname: Wallace
authors.forename: J M
authors.initials: JM
authors.lastname: Hyde
authors.forename: J
authors.initials: J
authors.lastname: Coplan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004192:Discrimination, Psychological / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009812:Odorants; D010775:Photic Stimulation; D012016:Reference Values; D012678:Sensation Disorders / Q000175:diagnosis; D012903:Smell / Q000502:physiology*