title: Indocyanine green videoangiographic findings in choroidal metastatic tumor.
abstract: BACKGROUND
  Indocyanine green videoangiography (ICGV) has recently advanced and become widely available as a clinical tool. We tested the efficacy of ICGV in evaluating metastatic choroidal tumors.
  
  
  METHODS
  ICGV using Topcon 50-IA was performed in five patients with clinically diagnosed choroidal metastatic tumors. The findings were compared with those of conventional fluorescein angiography (FAG).
  
  
  RESULTS
  Compared with FAG, ICGV demonstrated more smooth and regular hypofluorescent lesions, precisely indicating the exact size of the tumor. In all cases, no tumor vessels were found. The choroidal vascular integrity around the tumors was observed. FAG, however, was more sensitive in detecting the tumor development than ICGV when the extent of the hypofluorescent lesion could be seen clearly in the early phase. FAG provided more information regarding retinal pigment epithelial dysfunction in the outer blood retinal barrier overlying the tumor.
  
  
  CONCLUSIONS
  Since ICGV enables visualization of tumors through the retina, it is very useful, particularly in cases of associated secondary retinal detachment around the tumors. ICGV combined with FAG provides more precise assessment of the tumors themselves and their response to treatment than FAG alone.
authors.affiliation: Department of Ophthalmology, Yodogawa Christian Hospital, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Harino
authors.forename: K
authors.initials: K
authors.lastname: Miyamoto
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: R
authors.initials: R
authors.lastname: Tada
authors.forename: N
authors.initials: N
authors.lastname: Okamoto
authors.forename: M
authors.initials: M
authors.lastname: Fukuda
mesh_terms: D000230:Adenocarcinoma / Q000098:blood supply / Q000556:secondary*; D000368:Aged; D002283:Carcinoma, Bronchogenic / Q000098:blood supply / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary*; D002830:Choroid Neoplasms / Q000098:blood supply / Q000556:secondary*; D003110:Colonic Neoplasms / Q000473:pathology; D005260:Female; D019793:Fluorescein; D005451:Fluorescein Angiography; D005452:Fluoresceins; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000473:pathology; D014741:Video Recording
chemical_list: D005452:Fluoresceins; D007208:Indocyanine Green; D019793:Fluorescein