title: The DNA sequence of a 7941 bp fragment of the left arm of chromosome VII of Saccharomyces cerevisiae contains four open reading frames including the multicopy suppressor gene of the pop2 mutation and a putative serine/threonine protein kinase gene.
abstract: We report the sequence of a 7941 bp DNA fragment from the left arm of chromosome VII of Saccharomyces cerevisiae which contains four open reading frames (ORFs) of greater than 100 amino acid residues. ORF biC834 shows 100% bp identity with the recently identified multicopy suppressor gene of the pop2 mutation (MPT5); its deduced protein product carries an eight-repeat domain region, homologous to that found in the hypothetical regulatory YGL023 protein of S. cerevisiae and the Pumilio protein of Drosophila. ORF biE560 protein exhibits patterns typical of serine/threonine protein kinases, with which it shares high degrees of homology.
authors.affiliation: Department of Microbiology, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Coglievina
authors.forename: I
authors.initials: I
authors.lastname: Bertani
authors.forename: R
authors.initials: R
authors.lastname: Klima
authors.forename: P
authors.initials: P
authors.lastname: Zaccaria
authors.forename: C V
authors.initials: CV
authors.lastname: Bruschi
mesh_terms: D000595:Amino Acid Sequence; D015825:Chromosomes, Fungal; D004271:DNA, Fungal / Q000737:chemistry*; D005800:Genes, Fungal; D016153:Genes, Suppressor; D008969:Molecular Sequence Data; D009154:Mutation; D016366:Open Reading Frames; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D017346:Protein Serine-Threonine Kinases