title: Atypical demyelinating lesions in patients with multiple sclerosis.
abstract: We describe an atypical MRI appearance of multiple sclerosis (MS). Lesions characterized on T2-weighted images by a well-defined rim of increased signal intensity and a concentric region of higher signal intensity were seen in 6 of 132 patients with MS. On T1-weighted images these lesions were evident as regions of low signal intensity, often with a rim of contrast enhancement or increased signal intensity. These appearances tended to be shown by new, evolving lesions.
authors.affiliation: Department of Radiology, Medical College of Wisconsin, Milwaukee, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Yetkin
authors.forename: V M
authors.initials: VM
authors.lastname: Haughton
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D003711:Demyelinating Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000473:pathology*; D012189:Retrospective Studies