Intracranial pheochromocytoma--a case of noradrenaline-secreting glomus jugulare tumor.
A 43-year-old female was admitted for a labile hypertension and depression. High levels of plasma and urinary noradrenaline strongly suggested a pheochromocytoma. However, clinical investigations revealed a normal adrenal gland and thoraco-abdominal region. Venous samples from multiple sites indicated and increase in noradrenaline in the left jugular vein. Using computed tomography and Gadolinium DTPA (diethylene triamine pentaacetic acid)-enhanced dynamic MR (magnetic resonance) imaging, a tumor was discovered in the cerebello-pontine angle. Carotid angiography showed the feeder arteries clearly. Therefore, the tumor was classified as a noradrenaline-secreting glomus jugulare tumor fed by the carotid artery. After embolization and subsequent medical therapy, blood pressure was well controlled. Twenty cases of intracranial pheochromocytoma have been reported to date. This is the second such case in Japan.
Kudoh
Y
Y
Kidney Unit, South-One Hospital, Sapporo, Japan.
Kuroda
S
S
Shimamoto
K
K
Iimura
O
O
D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D002530:Cerebellopontine Angle; D003937:Diagnosis, Differential; D004110:Diltiazem / Q000627:therapeutic use; D004621:Embolization, Therapeutic; D005260:Female; D005925:Glomus Jugulare Tumor / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000628:therapy; D009543:Nifedipine / Q000627:therapeutic use; D009638:Norepinephrine / Q000378:metabolism*; D010673:Pheochromocytoma / Q000175:diagnosis
D004110:Diltiazem; D009543:Nifedipine; D009638:Norepinephrine