title: Glutathione S-transferases: alpha-naphthyl acetate activity and possible role in insecticide resistance.
abstract: Rat liver and house fly, Musca domestica L., glutathione S-transferases were purified by affinity chromatography and chromatofocusing. The specific activity with alpha-naphthyl acetate (a substrate, for general esterase activity) was determined. Some of the esterase activity that is normally assayed for resistance is apparently caused by the activity of the glutathione S-transferase.
authors.affiliation: Department of Toxicology, North Carolina State University, Raleigh 27695, USA.
authors.forename: J O
authors.initials: JO
authors.lastname: Lalah
authors.forename: C I
authors.initials: CI
authors.lastname: Chien
authors.forename: N
authors.initials: N
authors.lastname: Motoyama
authors.forename: W C
authors.initials: WC
authors.lastname: Dauterman
mesh_terms: D000818:Animals; D005982:Glutathione Transferase / Q000302:isolation & purification / Q000378:metabolism*; D006793:Houseflies / Q000201:enzymology*; D007305:Insecticide Resistance; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism; D009284:Naphthols / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity
chemical_list: D007527:Isoenzymes; D009284:Naphthols; C027876:alpha-naphthyl acetate; D005982:Glutathione Transferase