title: Impedance plethysmography as a screening procedure for asymptomatic deep venous thrombosis in a rehabilitation hospital.
abstract: OBJECTIVE
  Patients admitted for an inpatient rehabilitation treatment program almost uniformly have an elevated risk of deep venous thrombosis (DVT) and pulmonary embolism (PE). We assessed the value of impedance plethysmography (IPG) as a screening procedure for asymptomatic deep venous thrombosis in a series of patients admitted to our institution.
  
  
  METHODS
  Using a prospective observational study design, consecutive admissions to our facility for a period of almost one year were subjected to IPG within several days of admission.
  
  
  METHODS
  The study site was a 60-bed hospital-based rehabilitation center.
  
  
  METHODS
  Four hundred eighty-three consecutive patients were studied prospectively within several days of admission. Diagnoses included a variety of neurological disorders that resulted in significant weakness, intracranial surgery, orthopedic surgical procedures and fractures, joint replacements, and nonorthopedic postsurgical deconditioning. Three hundred eighteen patients were available for three-month follow-up.
  
  
  METHODS
  IPG was successfully completed in 301 patients. If IPG was positive, DVT was further assessed by duplex ultrasound (DU). When IPG and DU confirmed the presence of a DVT, administration of heparin and Coumadin was begun.
  
  
  METHODS
  Thirteen of 416 attempted IPG studies were positive for DVT, whereas DU confirmed the diagnosis in only 3 patients.
  
  
  RESULTS
  Follow-up found that six patients developed DVT or PE before discharge from our institution; five patients developed DVT or PE after discharge.
  
  
  CONCLUSIONS
  IPG has a poor yield as a screening tool for asymptomatic DVT on admission to an inpatient rehabilitation facility. The sensitivity and positive predictive value of IPG was too low to advocate its routine use in this setting.
authors.affiliation: St. Louis University School of Medicine, MO, USA.
authors.forename: R T
authors.initials: RT
authors.lastname: Katz
authors.forename: M M
authors.initials: MM
authors.lastname: McCulla
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D010992:Plethysmography, Impedance; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012047:Rehabilitation Centers; D012680:Sensitivity and Specificity; D013924:Thrombophlebitis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000925:Anticoagulants