A comparison of dentoalveolar and venous blood.
Dentoalveolar blood from extraction sites immediately after surgery and venous blood from 28 adult patients was compared for quantitative, qualitative, chemical, and cellular differences. The absence of stem cells, osteoblasts, and osteoclasts from dentoalveolar blood suggests a very low osteogenic potential, no more than that of venous blood. This finding contradicts information supplied by the manufacturer of a microporous, polymeric, composite graft material recommended for use with placement of implants in immediate extraction sites and as onlay grafts to treat ailing implants. The manufacturer's directions call for mixing the alloplast with bleeding marrow harvested from holes drilled in the mandibular symphysis or from a curetted dental socket immediately after a dental extraction in order to stimulate immature marrow cells to form osteoblasts.
Riesch
T
T
Oral and Maxillofacial Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York 10467-2490, USA.
Goldstein
M L
ML
Kraut
R A
RA
D000328:Adult; D000539:Alveolar Process / Q000098:blood supply*; D001769:Blood; D001773:Blood Cells; D006801:Humans; D008768:Methylmethacrylates; D010006:Osteoblasts; D010010:Osteoclasts; D010012:Osteogenesis / Q000502:physiology; D011102:Polyhydroxyethyl Methacrylate; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D013234:Stem Cells; D014680:Veins
D008768:Methylmethacrylates; D011102:Polyhydroxyethyl Methacrylate; C040206:HTR composite