title: [Neurologic manifestations following accidental exposure to pyralene and its thermal degradation products].
abstract: After five young women were exposed to pyralene and its thermal degradation products all developed a rich functional syndrome which could be explained by the traumatic effect of the accident. Nevertheless, in 3 of the women, abnormal somesthetic evoked potentials were observed including 2 with neurological lesions detectable radiologically. Polychlorobiphenyl derivates are toxic for the peripheral nervous system as has been observed in several recent exposure situations. Inversely, any effect on the central nervous system is still under debate.
authors.affiliation: Service des Maladies du Système Nerveux et du Muscle, CHU, Strasbourg.
authors.forename: J
authors.initials: J
authors.lastname: Reis
authors.forename: C
authors.initials: C
authors.lastname: Tranchant
authors.forename: J L
authors.initials: JL
authors.lastname: Dietemann
authors.forename: J M
authors.initials: JM
authors.lastname: Warter
mesh_terms: D000062:Accidents, Occupational; D000328:Adult; D001921:Brain / Q000187:drug effects*; D005071:Evoked Potentials / Q000187:drug effects; D005107:Explosions; D005260:Female; D005602:France; D006358:Hot Temperature; D006801:Humans; D008279:Magnetic Resonance Imaging; D009498:Neurotoxins; D016273:Occupational Exposure; D011078:Polychlorinated Biphenyls / Q000633:toxicity*
chemical_list: D009498:Neurotoxins; C013226:pyralene; D011078:Polychlorinated Biphenyls
vernacular_title: Manifestations neurologiques au décours d'une exposition accidentelle au pyralène et à ses produits de dégradation thermique.