title: Laser synovectomy of the knee joint. Experimental results on a new approach to joint surgery.
abstract: The clinical impact of laser-assisted synovectomy was investigated in a two-part study consisting of a morphological part with morphometric measurements and an in vivo part using an animal model. A continuous wave Nd:YAG laser (lambda = 1064 nm; power density 18-106 W/mm2; exposure 0.5-5 s) and a XeCl excimer laser (lambda = 308 nm; pulsewidth 20 ns; repetition rate 10-70 Hz; energy density 20-45 mJ/mm2; exposure 10-60 s) were employed in combination with a fused silica fiber with diameters of 600 microns and 800 microns, respectively. In vitro study. Under light microscopy, synovium exposed to Nd:YAG laser energy presents a transitional band (with a mean diameter of 2 mm) with three zones: a carbonized area, a vesicular zone, and a coagulated part. In contrast, pulsed UV-laser irradiation leads only to a narrow transitional zone extending 10-70 microns. Scanning electron microscopy reveals a clear-cut surface following excimer synovectomy, whereas Nd:YAG laser irradiation forms an irregular surface with numerous bursts due to vaporizing activity. In vivo study. Partial synovectomy of the knee joint was performed in two groups of 14 New Zealand white rabbits with a 1064-nm Nd:YAG laser and a 308-nm XeCl excimer laser. Another 14 animals synovectomized in a conventional technique served as a control. Morphological examination and histopathological scoring of the synovial membrane were performed 4 days to 6 months after the operation. The progress of synovial regeneration following excimer laser synovectomy did not differ from observations in the control group.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Abteilung für Allgemein-und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Raunest
authors.forename: E
authors.initials: E
authors.lastname: Derra
mesh_terms: D000818:Animals; D006801:Humans; D007719:Knee Joint / Q000473:pathology / Q000601:surgery*; D053685:Laser Therapy; D009354:Neodymium; D009985:Orthopedics / Q000379:methods; D011817:Rabbits; D000074402:Synovectomy; D013583:Synovial Membrane / Q000473:pathology; D015019:Yttrium
chemical_list: D009354:Neodymium; D015019:Yttrium