title: Functional significance of individual variations in callosal area.
abstract: We considered the hypothesis that the richness of callosal interhemispheric connections has a role in determining the degree of behavioural laterality and time-sharing ability in dual-task performance. Behavioural laterality as measured by dichotic word listening, line bisection and turning bias tests correlated inversely with the midsagittal cross-sectional area of the corpus callosum, as seen on MRI. The amount of dual task interference was strongly inversely correlated with the callosal area in both within-hemisphere and between-hemispheres conditions. These relationships between normal variations in callosal area, and outcomes on tests both of laterally and time-sharing capacity in normal adults suggest that the corpus callosum assumes a cross-excitatory role when subjects perform these tasks.
authors.affiliation: Child Study Center, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: M Y
authors.initials: MY
authors.lastname: Yazgan
authors.forename: B E
authors.initials: BE
authors.lastname: Wexler
authors.forename: M
authors.initials: M
authors.lastname: Kinsbourne
authors.forename: B
authors.initials: B
authors.lastname: Peterson
authors.forename: J F
authors.initials: JF
authors.lastname: Leckman
mesh_terms: D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D003337:Corpus Callosum / Q000502:physiology*; D004007:Dichotic Listening Tests; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007206:Individuality; D008279:Magnetic Resonance Imaging; D008297:Male; D009949:Orientation / Q000502:physiology; D013647:Task Performance and Analysis; D014796:Visual Perception / Q000502:physiology