[Antineutrophil cytoplasmic antibodies and Wegener's granulomatosis].
In the presented case are described the clinic demonstrations, analytical and evolutionary in a diagnosed patient of Wegener Granulomatosis (WG). The biopsies practiced in the injuries of the nasal mucous and oral cavity demonstrated a necrotizing granulomatous vasculitis. The antineutrophil cytoplasmic antibodies with standard cytoplasmic (AANC-C) determined by immunofluorescence indirect were positive with a seric initial of 1:160 in the making negative to the sixty treatment days. The administration of the treatment coincided with an improvement meaningful clinic. We emphasize the scarce demonstration of the WG in the oral cavity as well as of the presentation histological described. Finally, we emphasize the growing importance of the AANC-C not only in the diagnosis of the disease but as specific marker of its activity.
Gabriel Botella
F
F
Servicio de Medicina Interna, Hospital Clínico Universitario, Valencia.
Labios Gómez
M
M
Arnal Babiloni
M
M
Dasi Martínez
C
C
Vicente Ull
R
R
Mainar Latorre
L
L
D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers; D003593:Cytoplasm / Q000276:immunology*; D014890:Granulomatosis with Polyangiitis / Q000276:immunology*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000276:immunology*
D001323:Autoantibodies; D015415:Biomarkers
Anticuerpos anticitoplasma de neutrófilo y granulomatosis de Wegener.