title: Identification of molecules associated with the development of metastasis in human malignant melanoma.
abstract: Differential antibody reactivity has been used to identify molecules which change in expression or which are modified during tumor progression in human malignant melanoma. Such molecules may play a role in the development of the metastatic capacity of this tumor. Two of these molecules (ICAM-1 and MUC18) have been identified as cell adhesion molecules which are potentially involved in tumor-leukocyte-endothelial interactions.
authors.affiliation: Institute for Immunology, University of Munich, Germany.
authors.forename: J P
authors.initials: JP
authors.lastname: Johnson
mesh_terms: D000818:Animals; D000951:Antigens, Neoplasm / Q000502:physiology*; D002450:Cell Communication / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000502:physiology*; D008545:Melanoma / Q000473:pathology / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary*
chemical_list: D000951:Antigens, Neoplasm; D018799:Intercellular Adhesion Molecule-1