title: Serum ionized magnesium changes during and immediately after liver transplantation.
abstract: Alterations in magnesium (Mg) homeostasis during and after orthotopic liver transplantation are common. The purpose of this study is to compare total Mg (TMg), calculated ionized Mg (cMg++) and measured ionized Mg (mMg++) during and immediately following liver transplantation. The newly developed first generation ion selective electrode analyzer, AVL 988-4, was used to measure mMg++ in 63 serum samples from 3 transplant recipients and 48 serum samples from 48 healthy volunteers. Analysis was divided into intraoperative (stages 1 to 3) and postoperative periods. Decreased TMg, cMg++ and mMg++ levels were observed intraoperatively and > 2 weeks postoperatively. The cMg++ levels were consistently higher than mMg++, presumably owing to the fact that the equation used for the calculation does not take complex-Mg++ into account. A better correlation was observed between mMg++ and cMg++ in the transplant group (r = 0.87 to 0.99) compared to controls (r = 0.74). The usefulness of direct measurement of Mg++ in liver transplantation remains to be determined.
authors.affiliation: Department of Surgery, University of Texas Medical Branch, Galveston 77555, USA.
authors.forename: V
authors.initials: V
authors.lastname: Douzdjian
authors.forename: D
authors.initials: D
authors.lastname: Filos
authors.forename: A O
authors.initials: AO
authors.lastname: Okorodudu
mesh_terms: D000328:Adult; D002413:Cations, Divalent; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007432:Intraoperative Period; D016031:Liver Transplantation; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012044:Regression Analysis
chemical_list: D002413:Cations, Divalent; D008274:Magnesium