[An unusual incidence of carcinoid tumors and secondary malignancies].
A secondary malignancy is a common finding in carcinoid tumor patients. Several authors saw 7 to 36% of their carcinoid tumor patients developing an other malignancy. From 1965 to 1990 we treated 144 patients with a carcinoid tumor. During the follow-up time 24 (17%) developed a secondary tumor commonly sited in the gastrointestinal tract (8 colon carcinomas, 3 rectal carcinomas, 2 gastric carcinomas, 1 small bowel carcinoma, 1 esophageal cancer). The incidence is elevated 8 times in comparison to the normal population. One may speculate that a carcinoid patient possesses an increased susceptibility to all forms of malignancy. As a consequence all the carcinoid tumor patients should be thoroughly investigated and should be followed up in short terms. Central point of interest should be the gastrointestinal tract.
Schneider
C
C
Chirurgische Klinik, Universität Erlangen-Nürnberg.
Wittekind
C
C
Köckerling
F
F
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002423:Cause of Death; D004064:Digestive System / Q000473:pathology; D013505:Digestive System Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000601:surgery; D008875:Middle Aged; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D015996:Survival Rate
Aussergewöhnliche Häufung von Carcinoidtumoren und Zweitmalignomen.