Developmental transformation of dendritic arbors in mouse whisker thalamus.
Neurons in slices though the somatosensory thalamus of postnatal day 6 and adult mice were injected with Lucifer yellow. Dendritic arbors on postnatal day 6 are confined to single barreloids (single whisker representations); in adults they are seven times longer, extending beyond their barreloid to adjacent barreloids. The postnatal transformation of dendritic arbors by total process growth and extension to adjacent barreloids suggests a developmental change in the role of these cells from instructing whisker pattern formation to integrating sensory information from more than one whisker.
Brown
K E
KE
Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.
Arends
J J
JJ
Wasserstrom
S P
SP
Zantua
J B
JB
Jacquin
M F
MF
Woolsey
T A
TA
D000375:Aging / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D003712:Dendrites / Q000502:physiology*; D005456:Fluorescent Dyes; D066298:In Vitro Techniques; D007546:Isoquinolines; D051379:Mice; D008815:Mice, Inbred Strains; D013788:Thalamus / Q000254:growth & development / Q000502:physiology* / Q000648:ultrastructure*; D014738:Vibrissae / Q000502:physiology*
D005456:Fluorescent Dyes; D007546:Isoquinolines; C017475:lucifer yellow