title: Nasal or oral oil application on infants: a possible risk factor for adult bronchiectasis.
abstract: Lipid pneumonia has been observed in infants exposed by inhalation of oil or butter applied into the nose or throat as part of an old custom. We performed a case-control study to test the hypothesis, that this ancient tradition may be a predisposing factor to bronchiectasis. A case group of 59 patients with bronchiectasis and three control groups -46 patients with COPD, 32 asthmatics, and 71 healthy Saudis-were questioned about possible risk factors of bronchiectasis including nasal or oral application of oil/butter at infancy. The risk of witnessed exposure to this old folk remedy was significantly higher among the cases than the controls (OR = 3.9 (1.7-8.8), (95% confidence interval) p < 0.001). Application of oil or butter into the nasal or oral cavity of infants may be a risk factor for bronchiectasis.
authors.affiliation: Medical Department P, Bispebjerg Hospital, Copenhagen, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Døssing
authors.forename: J H
authors.initials: JH
authors.lastname: Khan
mesh_terms: D000281:Administration, Intranasal; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D001249:Asthma / Q000209:etiology; D001987:Bronchiectasis / Q000209:etiology*; D016022:Case-Control Studies; D016001:Confidence Intervals; D003469:Culture; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007223:Infant; D008173:Lung Diseases, Obstructive / Q000209:etiology; D008297:Male; D008519:Medicine, Traditional; D008875:Middle Aged; D009821:Oils / Q000008:administration & dosage* / Q000009:adverse effects*; D011017:Pneumonia, Lipid / Q000209:etiology; D012307:Risk Factors; D012529:Saudi Arabia; D012907:Smoking / Q000009:adverse effects
chemical_list: D000393:Air Pollutants; D000395:Air Pollutants, Occupational; D009821:Oils