Primary lymphoma of the spleen. Report of a case with diagnosis by fine-needle guided biopsy.
Primary splenic lymphoma is a relatively infrequent disease; the diagnosis of this entity is currently made with splenectomy. In a 52-year-old female with left upper quadrant abdominal pain, ultrasound showed a normal-sized spleen with an internal hypoechoic focal lesion. Ultrasonically-guided fine-needle aspiration and tissue core biopsy of the splenic lesion showed non-Hodgkin's lymphoma (NHL). At the time of presentation there was no evidence of involvement of lymph nodes, bone marrow or any other organ. A diagnosis of primary splenic non-Hodgkin's lymphoma was made and the patient underwent laparotomy with splenectomy. Histologic examination of the spleen confirmed the diagnosis: low-grade NHL confined to the spleen. The patient is well and in complete remission seven months after diagnosis. The purpose of this paper is to report a rare occurrence of primary splenic lymphoma and to demonstrate the possibility of making this diagnosis by percutaneous guided biopsy.
Cavanna
L
L
1a Div. Medica, Ospedale di Piacenza, Italy.
Artioli
F
F
Vallisa
D
D
Di Donato
C
C
Bertè
R
R
Carapezzi
C
C
Foroni
R
R
Del Vecchio
C
C
Lo Monaco
B
B
Prati
R
R
D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D008875:Middle Aged; D013160:Splenic Neoplasms / Q000473:pathology*; D014465:Ultrasonics