title: Topical treatment of Sjögren-Larsson syndrome with calcipotriol.
abstract: Two patients with Sjögren-Larsson syndrome were treated with calcipotriol in ointment and the ointment base only for 12 weeks, using a double-blind bilaterally paired comparative study. Unilateral improvement was observed in both patients in favour of the calcipotriol-treated side. The present case is the first demonstration of a substantial clinical effect of calcipotriol in the Sjögren-Larsson syndrome.
authors.affiliation: Department of Dermatology, University Hospital, Nijmegen, The Netherlands.
authors.forename: G P
authors.initials: GP
authors.lastname: Lucker
authors.forename: P C
authors.initials: PC
authors.lastname: van de Kerkhof
authors.forename: J R
authors.initials: JR
authors.lastname: Cruysberg
authors.forename: D J
authors.initials: DJ
authors.lastname: der Kinderen
authors.forename: P M
authors.initials: PM
authors.lastname: Steijlen
mesh_terms: D000328:Adult; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009824:Ointments; D016111:Sjogren-Larsson Syndrome / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol