[The initial clinical manifestations of rhabdomyosarcoma].
Unilateral proptosis, dislocation of the globe and impairment of motility in childhood are known to be typical presenting signs of rhabdomyosarcoma of the orbit. In a retrospective analysis of 17 patients with rhabdomyosarcoma (1974-1993) only 8 patients presented with typical signs. 9 patients did never show the typical signs which initially lead to a wrong diagnosis in many cases. A 5-year-old boy complained of a conjunctival cyst in the lower fornix of the left eye. Two weeks later the cyst was replaced by a solid tumor. The tumor was not completely resectable, histology revealed an embryonal rhabdomyosarcoma. Presenting signs and symptoms of orbital rhabdomyosarcoma show a sometimes misleading variety including conjunctival cyst formation. In any recent onset of unilateral rapidly progressing alterations of the lid, the conjunctiva or the caruncle in childhood the physician should consider a rhabsomyosarcoma of the orbit.
Schworm
H D
HD
Augenklinik, Universität München.
Boergen
K P
KP
Stefani
F H
FH
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005094:Exophthalmos / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009915:Orbit / Q000473:pathology / Q000601:surgery; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D018233:Rhabdomyosarcoma, Embryonal / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
Klinische Erstmanifestationen des orbitalen Rhabdomyosarkoms.