Altered substrate and inhibitor specificity of purified human adult thymidine kinases (TK2) from leukemic cells.
Munch-Petersen
B
B
Institute of Life Sciences and Chemistry, Roskilde University, Denmark.
Völker
C
C
Cloos
L
L
Hofbauer
R
R
Mortensen
B T
BT
Tyrsted
G
G
D000328:Adult; D002460:Cell Line; D005467:Floxuridine / Q000494:pharmacology; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D015470:Leukemia, Myeloid, Acute / Q000145:classification / Q000201:enzymology*; D015473:Leukemia, Promyelocytic, Acute; D012016:Reference Values; D013379:Substrate Specificity; D013937:Thymidine Kinase / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D013942:Thymine Nucleotides / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D015215:Zidovudine / Q000494:pharmacology
D007527:Isoenzymes; D013942:Thymine Nucleotides; D005467:Floxuridine; D015215:Zidovudine; D013937:Thymidine Kinase; C024157:thymidine 5'-triphosphate