title: Study of interleukin-2 receptor in schistosomiasis mansoni and its analogous changes in collagen diseases and schistosomal arthropathy.
abstract: An enzyme linked immunosorbent assay was used to quantify soluble interleukin-2 receptor (sIL-2R) in the serum of patients with different stages of S. mansoni infection, rheumatoid arthritis, systemic lupus erythematosus (SLE) and schistosomal arthropathy. The results demonstrated significant higher level of sIL-2R in different patient groups compared to the control group. The highest level of sIL-2R was recorded in hepatosplenic schistosomiasis complicated with ascites. The difference was statistically significant compared to other groups. There was no significant difference in sIL-2R regarding rheumatoid arthritis and SLE. Schistosomal arthropathy group showed significant higher level of sIL-2R compared to rheumatoid arthritis, SLE and early S. mansoni infection while the difference was insignificant compared to hepatosplenic schistosomiasis without ascites.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors.forename: H M
authors.initials: HM
authors.lastname: Khalil
authors.forename: A G
authors.initials: AG
authors.lastname: el Missiry
authors.forename: H M
authors.initials: HM
authors.lastname: Fahmy
authors.forename: N M
authors.initials: NM
authors.lastname: Khalil
authors.lastname: Nadia
authors.forename: M
authors.initials: M
authors.lastname: Sabry
authors.forename: H E
authors.initials: HE
authors.lastname: Abdel Atty
authors.forename: F A
authors.initials: FA
authors.lastname: Tamara
authors.forename: N
authors.initials: N
authors.lastname: Amer
authors.forename: H G
authors.initials: HG
authors.lastname: el Baz
mesh_terms: D001170:Arthritis, Infectious / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D003095:Collagen Diseases / Q000097:blood / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012555:Schistosomiasis mansoni / Q000097:blood / Q000276:immunology* / Q000503:physiopathology
chemical_list: D015415:Biomarkers; D015375:Receptors, Interleukin-2