title: Basal cell carcinoma and lifestyle characteristics.
abstract: BACKGROUND
  A number of lifestyle factors are important in the etiology of basal cell carcinoma. Previous studies have investigated smoking, alcohol, diet, and sun exposure as possible contributing factors. No previous studies have investigated case-controlled lifestyle influences in basal cell carcinomas referred for Mohs micrographic surgery.
  
  
  METHODS
  Cases were obtained from Mohs-referred basal cell carcinoma patients. Matched controls were selected from a busy dermatology clinic. The only criteria for selection of controls was never having had cancer previously. Cases and controls were surveyed regarding lifestyle characteristics.
  
  
  RESULTS
  Forty-six age, sex, and skintype-matched controls were compared. Sun exposure, alcohol, and smoking were not significant factors. Dietary fat, fiber, and the vitamins A, C, and beta carotene, as well as selenium showed important, but not significant differences. Caffeine consumption was higher in the cancer group.
  
  
  CONCLUSIONS
  Our findings agree with previously published studies in regard to antioxidant consumption as a protective factor for basal cell carcinoma. Caffeine consumption was higher in the cancer patients.
authors.affiliation: West River Dermatology, Rapid City, SD 57701, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Sahl
authors.forename: S
authors.initials: S
authors.lastname: Glore
authors.forename: P
authors.initials: P
authors.lastname: Garrison
authors.forename: K
authors.initials: K
authors.lastname: Oakleaf
authors.forename: S D
authors.initials: SD
authors.lastname: Johnson
mesh_terms: D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D001205:Ascorbic Acid / Q000008:administration & dosage; D002110:Caffeine / Q000009:adverse effects; D002280:Basal Cell Carcinoma / Q000453:epidemiology* / Q000517:prevention & control / Q000601:surgery; D002338:Carotenoids / Q000008:administration & dosage; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D012307:Risk Factors; D012643:Selenium / Q000008:administration & dosage; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000517:prevention & control / Q000601:surgery; D012907:Smoking / Q000009:adverse effects; D014810:Vitamin E / Q000008:administration & dosage; D019207:beta Carotene
chemical_list: D019207:beta Carotene; D014810:Vitamin E; D002338:Carotenoids; D002110:Caffeine; D012643:Selenium; D001205:Ascorbic Acid