[The effect of hemosorption and plasmapheresis on fibrinogen-125I kinetics in patients with rheumatoid arthritis].
125I-labelled fibrinogen kinetics has been studied in 73 patients with rheumatoid arthritis (RA). Of them, 53 subjects underwent hemosorptions or hemosorptions combined with plasmapheresis. Fibrinogen metabolism in RA patients appeared enhanced versus healthy controls. It was observed that hemosorption treatment or its combination with plasmapheresis produce positive changes in clinical and laboratory RA parameters, improve fibrinogen metabolism. The study of fibrinogen kinetics is useful in assessing efficacy of on-going treatment.
Bazhanov
A N
AN
Golubeva
L V
LV
Trusov
V V
VV
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006464:Hemoperfusion / Q000379:methods; D006801:Humans; D007457:Iodine Radioisotopes; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis / Q000379:methods; D013997:Time Factors
D007457:Iodine Radioisotopes; D005340:Fibrinogen
Vliianie gemosorbtsii i plazmafereza na kinetiku fibrinogena-125I u bol'nykh revmatoidnym artritom.