A pathologist's view of prostatic carcinoma.
In this article, the pathologic findings of carcinoma of the prostate were reviewed. Criteria were discussed for the pathologic diagnosis of prostatic carcinoma (PC), premalignant lesions, lesions that simulate PC, immunopathologic findings, special types of PC, effects of therapy on the prostate, and recent efforts to improve diagnostic and prognostic capabilities. The possible role of the study of nucleolar organizing regions was reported. A new method for demonstrating chromosomes in formaldehyde-fixed paraffin-embedded tissue was mentioned. The need for research in all aspects of the pathology of prostatic cancer was emphasized.
Mostofi
F K
FK
Department of Genitourinary Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Sesterhenn
I A
IA
Davis
C J
CJ
D000135:Acid Phosphatase / Q000032:analysis; D002467:Cell Nucleus / Q000473:pathology; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011230:Precancerous Conditions / Q000473:pathology; D011379:Prognosis; D011467:Prostate / Q000737:chemistry / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000032:analysis; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy
D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen