Visual discrimination learning in spontaneously hypertensive (SHR) and Wistar normotensive rats: computerized analysis of choice strategies.
Spontaneously hypertensive rats (SHR) were found to learn a visual discrimination paradigm better than Wistar normotensive rats (NT). The present analysis of choice strategies used by rats was performed to detect possible correlates between patterns of responding and duration of learning. The following strategies were included into the analysis: perseveration and alternation of choice (response-set hypotheses), win-stay lose-shift and win-shift lose-stay (prediction hypotheses). A computer programme called "The Thinking Rat" was written to analyse rat strategies during the learning. The analysis was applied for two irrelevant dimensions of stimuli, i.e. position and orientation, and for colour as a relevant cue. SHR solved the task using different strategies than the NT rats. All subjects began by responding to position as a cue, but SHR gave up this strategy more quickly than NT rats did and responded earlier to colour. NT rats showed a strong preference to persevere in their choices with respect to stimulus position, whereas SHR used more frequently the prediction hypotheses with respect to colour. The analysis of performance and the analysis of choice strategies-could indicate that the discrepancy in learning between SHR and NT rats may be caused by differences in attention.
Niewiadomska
G
G
Department of Neurophysiology, Nencki Institute of Experimental Biology, Warsaw, Poland.
Niewiadomski
W
W
D000704:Analysis of Variance; D000818:Animals; D004192:Discrimination, Psychological; D007858:Learning; D008297:Male; D008959:Models, Neurological; D051381:Rats; D011918:Rats, Inbred SHR / Q000502:physiology*; D017208:Rats, Wistar / Q000502:physiology; D012016:Reference Values; D012984:Software; D014796:Visual Perception