A basic residue C-terminal to tyrosine compromises its viability as a tyrosine kinase target.
Keane
N E
NE
NMR Unit, School of Biochemistry, University of Birmingham, U.K.
Quirk
P G
PG
Levine
B A
BA
Chavanieu
A
A
Calas
B
B
Gao
Y
Y
Wei
L
L
Ellis
L
L
D000595:Amino Acid Sequence; D066246:ErbB Receptors / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D010766:Phosphorylation; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D011972:Receptor, Insulin / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity; D014443:Tyrosine
D014443:Tyrosine; D066246:ErbB Receptors; D011505:Protein-Tyrosine Kinases; D011972:Receptor, Insulin