[Serum gastrin and somatostatin in diseases of the stomach].
Gastrin and somatostatin are enterohormones which influence several physiological processes in the gastrointestinal tract. Gastrin has a pro-malignant and pro-ulcerogenic effect, while somatostatin deficiency has a similar effect. The authors examined in their investigation the 24-hour secretion of both hormones in patients with gastric ulcer and atypical gastric conditions. They revealed a significant difference in the 24-hour somatostatin level which was higher in patients with atypical gastric conditions (p < 0.05). The finding may suggest a more intense reaction of somatostatin to malignant than to non-malignant disease. In the other compared parameters no statistically significant difference was revealed.
Payer
J
J
I. interná klinika FN, Bratislava.
Huorka
M
M
Duris
I
I
Randus
V
V
Ondrejka
P
P
Kratochvíl'ová
H
H
D000328:Adult; D000368:Aged; D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000097:blood; D013004:Somatostatin / Q000097:blood*; D013272:Stomach Diseases / Q000097:blood*
D005755:Gastrins; D013004:Somatostatin
Sérový gastrín a somatostatín u ochorení źalúdka.