title: Transposition of the antropylorus for anal incontinence--an experimental model in the pig.
abstract: An experimental model in the pig rendered incontinent of feces was developed to assess the sphincteric activity of the transposed antropylorus. In the control group, normal defecation was studied clinically, radiologically, and manometrically. Nineteen 7- to 10-week-old pigs were rendered incontinent by resection of 20 cm of colon and rectum to below the dentate line. The antropylorus was prepared on its own blood supply and transposed to the anus, initially with a colostomy, which was closed 15 to 21 days later. Clinically these pigs passed semisolid stool in a piecemeal fashion. Contrast defecography showed hold-up at the pylorus, reflux of contrast into the colon, with pyloric contraction independent of antral stimulation. Manometry showed pyloric contraction with rise in antral pressure and independence. The authors conclude that transposition of an antropyloric segment to the anus provides a sphincter-like mechanism and could have application in fecal incontinence.
authors.affiliation: Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Rondebosch, South Africa.
authors.forename: E
authors.initials: E
authors.lastname: Erdogan
authors.forename: H
authors.initials: H
authors.lastname: Rode
authors.forename: R
authors.initials: R
authors.lastname: Hickman
authors.forename: S
authors.initials: S
authors.lastname: Cywes
mesh_terms: D000818:Animals; D003672:Defecation; D005242:Fecal Incontinence / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D011312:Pressure; D011708:Pylorus / Q000637:transplantation*; D013552:Swine; D016896:Treatment Outcome