title: [The effect of hydrodynamic conditions on the interferon-synthesizing activity of swine splenocytes in the production of alpha-interferon].
abstract: Parameters of physical constituents of the agitation process and mass-exchange characteristics of the suggested bioreactor for suspension cultivation of pig splenocytes are determined. The effect of hydrodynamic conditions on viability and interferon-synthesizing activity of cells in production of alpha-interferon of pigs has been studied. The relation existing between interferonogenesis processes proceeding under suspension and under stationary biosynthesis has been analyzed by the pair correlation method.
authors.forename: V D
authors.initials: VD
authors.lastname: Dumanskiĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Povodzinskiĭ
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Karlash
authors.forename: V K
authors.initials: VK
authors.lastname: Ivanenko
authors.forename: A V
authors.initials: AV
authors.lastname: Seleznev
authors.forename: S P
authors.initials: SP
authors.lastname: Tsygankov
authors.forename: Ia G
authors.initials: IaG
authors.lastname: Kishko
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D016898:Interferon-alpha / Q000096:biosynthesis*; D008433:Mathematics; D013154:Spleen / Q000166:cytology / Q000378:metabolism*; D013552:Swine
chemical_list: D016898:Interferon-alpha
vernacular_title: Vliianie gidrodinamicheskikh usloviĭ na interferonsinteziruiushchuiu aktivnost' splenotsitov svineĭ pri poluchenii al'fa-interferona.