title: [The effect of beta-adrenoblockaders on the elasticity of the vessels of the greater circulation].
abstract: Experiments in anesthesized cats have shown that the two non-selective beta-adrenergic blocking drugs anapriline (propranolol) and tobanum (cloranolol hydrochloride) enhance vasodilation caused by increasing the blood flow volumetric velocity through the vascular region. It is suggested that the cause of increased vascular bed distensibility induced by these compounds is their capacity to release endothelium-relaxing factor. The cardiac selective beta-adrenoblocker metoprolol tartate had no effects on the regulation of vascular tone.
authors.forename: A V
authors.initials: AV
authors.lastname: Syrenskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Tsyrlin
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D001158:Arteries / Q000187:drug effects / Q000502:physiology; D001775:Blood Circulation / Q000187:drug effects*; D002415:Cats; D006439:Hemodynamics / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects*
chemical_list: D000319:Adrenergic beta-Antagonists
vernacular_title: Vliianie beta-adrenoblokatorov na rastiazhimost' sosudov bol'shogo kruga krovoobrashcheniia.