title: Systemic histiocytosis in the Bernese mountain dog.
abstract: Systemic histiocytosis is a rare familial histiocytic disorder seen in the Bernese mountain dog. This article documents six confirmed cases of the disease seen at the Animal Medical Centre between June 1992 and June 1994 and describes the different presentations of the disease, response to therapy and progression. Three of the dogs are still alive; of these, two are in remission six and 18 months later and in one case the owner refused treatment. Three of the cases were euthanased for humane reasons.
authors.affiliation: Animal Medical Centre, Chorlton, Manchester.
authors.forename: S
authors.initials: S
authors.lastname: Paterson
authors.forename: P
authors.initials: P
authors.lastname: Boydell
authors.forename: R
authors.initials: R
authors.lastname: Pike
mesh_terms: D000818:Animals; D001947:Breeding; D003231:Conjunctivitis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D003320:Corneal Ulcer / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy / Q000473:pathology*; D004285:Dogs; D015614:Histiocytosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009824:Ointments; D009883:Ophthalmic Solutions; D015423:Scleritis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D009883:Ophthalmic Solutions