[Structural chromosome aberrations in the peripheral blood lymphocytes in patients with precancer and endometrial cancer].
The level of chromosomal aberrations in cultured blood lymphocytes from patients with hyperplasia, atypical hyperplasia of endometrium and endometrial cancer was studied. Chromosomal aberration frequency significantly increased up to 5.000 +/- 00.47% in patients with atypical and endometrial hyperplasia and to 5.21 +/- 00.53% in patients with endometrial cancer in comparison to 0.67 +/- 0.21% in the control. All indices were more pronounced in endometrial cancer patients with pathology in pedigree.
Polishchuk
L Z
LZ
Nesina
I P
IP
D000230:Adenocarcinoma / Q000097:blood* / Q000235:genetics; D000328:Adult; D000368:Aged; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D004714:Endometrial Hyperplasia / Q000097:blood / Q000235:genetics; D016889:Endometrial Neoplasms / Q000097:blood* / Q000235:genetics; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008875:Middle Aged; D011230:Precancerous Conditions / Q000097:blood* / Q000235:genetics
Strukturnye aberratsii khromosom v limfotsitakh perifericheskoĭ krovi u bol'nykh predrakom i rakom éndometriia.