Treatment of cicatricial pemphigoid with tetracycline and nicotinamide.
Cicatricial pemphigoid is a rare autoimmune blistering disease involving predominantly mucosal areas in elderly patients. It runs a chronic relapsing course. Immunosuppressive treatments are frequently complicated by adverse effects and require careful monitoring. A 69-year-old woman is reported who responded well to a simple regimen of combined tetracycline and nicotinamide after 15 years of inadequate disease control and numerous adverse effects from immunosuppressive agents.
Poskitt
L
L
Dermatology Department, Amersham General Hospital, Bucks, UK.
Wojnarowska
F
F
D000368:Aged; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009536:Niacinamide / Q000627:therapeutic use*; D010118:Oxytetracycline / Q000627:therapeutic use*; D010390:Pemphigoid, Benign Mucous Membrane / Q000188:drug therapy*
D009536:Niacinamide; D010118:Oxytetracycline