[The treatment of hepatic encephalopathy with Hepa-Mertz].
A course of hepamerz treatment (7 intravenous drip infusions followed by oral administration for 14 days) was tried in 14 patients with hepatic cirrhosis to clarify hepamerz effects on hepatic encephalopathy and hyperammonemia which were judged by blood ammonium levels and time of psychomotor tests. All the patients responded. Fasting ammonium levels reduced in 67%, after meal in 82% of patients, 68% improved their psychomotor parameters. Transient nausea as a side effect occurred in 3 patients.
Podymova
S D
SD
Bueverov
A O
AO
Nadinskaia
M Iu
MIu
D000641:Ammonia / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D004151:Dipeptides / Q000009:adverse effects / Q000627:therapeutic use*; D006501:Hepatic Encephalopathy / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000209:etiology; D011597:Psychomotor Performance / Q000187:drug effects; D013997:Time Factors
D015415:Biomarkers; D004151:Dipeptides; D000641:Ammonia; C002939:ornithylaspartate
Lechenie pechenochnoĭ éntsefalopatii preparatom gepa-merts.