title: Clinico-pathological correlation of glucagon-positive pancreatic endocrine tumours: a presentation of five cases.
abstract: The clinicopathologic correlation of five cases of glucagon-positive pancreatic tumours is reviewed. Two cases with the typical glucagonoma syndrome but with atypical manifestations in the central nervous system are presented. These neurological manifestations might constitute a new paraneoplastic syndrome. The last three cases illustrate how glucagon positivity can be present in pancreatic endocrine tumours other than in the classical glucagonoma.
authors.affiliation: Department of Medicine, University of Hong Kong, Queen Mary Hospital.
authors.forename: M S
authors.initials: MS
authors.lastname: Wat
authors.forename: K Y
authors.initials: KY
authors.lastname: Lam
authors.forename: K S
authors.initials: KS
authors.lastname: Lam
mesh_terms: D000328:Adult; D004701:Endocrine Gland Neoplasms / Q000378:metabolism*; D005260:Female; D005934:Glucagon / Q000378:metabolism*; D005935:Glucagonoma / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000378:metabolism*
chemical_list: D005934:Glucagon