Comparison of 5-fluoro-2'-deoxyuridine and 5-fluorouracil in the treatment of murine colon cancer; effects on thymidylate synthase.
van der Wilt
C L
CL
Dept. of Medical Oncology, Free University Hospital, Amsterdam, The Netherlands.
van Laar
J A
JA
Smid
K
K
Rustum
Y M
YM
Peters
G J
GJ
D000818:Animals; D001711:Biotransformation; D002460:Cell Line; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D005260:Female; D005467:Floxuridine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D005468:Fluorodeoxyuridylate / Q000378:metabolism; D005472:Fluorouracil / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D051379:Mice; D008807:Mice, Inbred BALB C; D013940:Thymidylate Synthase / Q000378:metabolism*
D005467:Floxuridine; D005468:Fluorodeoxyuridylate; D013940:Thymidylate Synthase; D005472:Fluorouracil