title: Dorsal hippocampal lesions impair blocking but not latent inhibition of taste aversion learning in rats.
abstract: The aim of the present experiments was to study the effect of nonselective electrolytic lesions of the rat dorsal hippocampus on 2 learning phenomena: the L.J. Kamin (1969) blocking effect and latent inhibition of taste aversion learning. Bilateral dorsal hippocampal lesions selectively impaired blocking induced by 1 saccharin-lithium chloride pairing previous to 1 serial compound (saccharin-cider vinegar)-lithium pairing, but lesions had no effect on latent inhibition of a saline aversion, induced by 6 saline preexposures, in the same group of animals. Moreover, dorsal hippocampal lesions did not affect latent inhibition of saccharin-conditioned aversion induced by 1 or 6 preexposures. It is argued that blocking and latent inhibition of taste aversion learning do not share a common neural mechanism.
authors.affiliation: Department of Experimental Psychology and Physiology of Behavior, University of Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Gallo
authors.forename: A
authors.initials: A
authors.lastname: Cándido
mesh_terms: D000818:Animals; D001245:Association Learning; D001362:Avoidance Learning / Q000502:physiology*; D001931:Brain Mapping; D003214:Conditioning, Classical / Q000502:physiology*; D006624:Hippocampus / Q000502:physiology*; D018021:Lithium Chloride / Q000633:toxicity; D008297:Male; D011939:Mental Recall / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013649:Taste / Q000502:physiology*
chemical_list: D018021:Lithium Chloride