[C-reactive protein (CRP)--an acute-phase protein with importance in laboratory medicine in veterinary medicine].
CRP is an acute phase protein (APP) formed by hepatic cells in acute phase reaction (APR). APR is initiated by a broad spectrum of cytokines of activated macrophages of blood and tissues. During the APR, plasma concentrations of APP are changed. Cytokines regulate APPs. CRP is a phylogenetically very old molecule. The degree of homology of amino acids in CRP is very high in a lot of species. CRP binding specificities depend on Ca++. The diagnostic importance of CRP in veterinary medicine is discussed.
Krüger
M
M
Institut für Bakteriologie und Mykologie der Veterinärmedizinischen Fakultät der Universität Leipzig.
Schrödl
W
W
Lindner
A
A
Kunze
R
R
D000818:Animals; D002097:C-Reactive Protein / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D019411:Clinical Laboratory Techniques / Q000662:veterinary*; D016207:Cytokines / Q000502:physiology; D008099:Liver / Q000378:metabolism; D008262:Macrophage Activation; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid
D016207:Cytokines; D002097:C-Reactive Protein
C-reaktives Protein (CRP)--ein Akute-Phase-Protein mit labormedizinischer Bedeutung in der Veterinärmedizin.