title: [Ataxia telangiectasia].
abstract: Ataxia telangiectasia is a genetically determined multi-system disorder in which senile skin changes are at an early stage. The patients have progressive neurological disability, cellular and humoral immunodeficiencies and increased cancer incidence. Heterozygous carriers of the gene, estimated to comprise about 1% of the general population, have an increased risk of cancer. We have initiated an identification of a cohort of patients and their relatives in order to evaluate their cancer risk.
authors.affiliation: Odense Universitetshospital, børneafdelingen.
authors.forename: L K
authors.initials: LK
authors.lastname: Hansen
authors.forename: K
authors.initials: K
authors.lastname: Wulff
authors.forename: N J
authors.initials: NJ
authors.lastname: Seersholm
mesh_terms: D000293:Adolescent; D001260:Ataxia Telangiectasia / Q000150:complications / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000209:etiology; D011379:Prognosis; D012307:Risk Factors
vernacular_title: Ataxia telangiectasia.