title: Cultured epidermal allografts for the treatment of deep dermal burns.
abstract: The paper summarizes the experience with the application of cultured epidermal allografts in the treatment of deep dermal burns. In a series of patients, including 10 adults and 32 children this method allowed to attain an epithelialization in 90% of deep dermal burns. The advantages of this therapeutic method consist particularly in the early epithelialization of the burnt area and the maintenance of all vital layers of the corium. The risk of a transmission of infection by the transplantation of allografts of live human cells can be minimalized by keeping all directions prescribed for the examination of donors. The possibility of cryopreservation and the easy transport of cultured epidermal allografts renders them available for the use as a new therapeutic method in the treatment of deep dermal burns.
authors.affiliation: Burn Centre, University Hospital, Brno-Bohunice.
authors.forename: P
authors.initials: P
authors.lastname: Brychta
authors.forename: I
authors.initials: I
authors.lastname: Suchánek
authors.forename: H
authors.initials: H
authors.lastname: Ríhová
authors.forename: J
authors.initials: J
authors.lastname: Adler
authors.forename: J
authors.initials: J
authors.lastname: Komárková
mesh_terms: D000328:Adult; D002056:Burns / Q000601:surgery*; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D015925:Cryopreservation; D046508:Culture Techniques; D004817:Epidermis / Q000637:transplantation*; D005260:Female; D006801:Humans; D007223:Infant; D015603:Keratinocytes / Q000166:cytology; D008297:Male; D014021:Tissue Preservation; D014184:Transplantation, Homologous; D014945:Wound Healing