title: Steryl glycosides: a characteristic feature of the Helicobacter spp.?
abstract: The lipids of different species of Helicobacter (H.felis, H. muridarum, H. mustelae, H. fennelliae, and H. cinaedi) were studied. Different types of cholesteryl glucosides were found in all of the species studied except H. cinaedi. The total amount of cholesteryl glucosides varied from 14.8% of total lipids in H. mustelae to 33.1% of total lipids in H. felis. The different types of cholesteryl glucosides and their species distribution are cholesteryl-6-O-acyl-alpha-D-glucopyranoside (cholesteryl-6-O-tetradecanoyl-alpha-D-glucopyranoside in H. felis and cholesteryl-6-O-dodecanoyl-alpha-D-glucopyranoside in H. muridarum), cholesteryl-alpha-D-glucopyranoside (H. felis, H. muridarum, H. mustelae, and H. fennelliae), and cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside (H. fennelliae). The neutral lipid fractions showed a high percentage of cholesterol, with selective accumulation of free cholesterol. The study thus shows that the characteristic presence of steryl glycosides in Helicobacter spp. may be an important chemotaxonomic marker for many of the species, and the helicobacters show a selective accumulation of free cholesterol from the media.
authors.affiliation: Department of Bacteriology, Okayama University Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Haque
authors.forename: Y
authors.initials: Y
authors.lastname: Hirai
authors.forename: K
authors.initials: K
authors.lastname: Yokota
authors.forename: K
authors.initials: K
authors.lastname: Oguma
mesh_terms: D002784:Cholesterol / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D005227:Fatty Acids / Q000032:analysis; D016998:Helicobacter / Q000737:chemistry*; D008055:Lipids / Q000032:analysis; D008970:Molecular Weight
chemical_list: D005227:Fatty Acids; D008055:Lipids; C027578:cholesteryl glucoside; D002784:Cholesterol