title: Fulminant amebiasis: a clinical evaluation.
abstract: Two patients with fulminant amebic colitis with colon perforation and concomitant liver abscess were collected over the last 5 years. One patient underwent emergency laparotomy to treat amebic cecal perforation. Diverted ileostomy saved his life. The ileostomy was successfully reversed 6 months later. The other patient underwent 4 laparotomies with more invasive procedures in less than 1 month due to sequential complications of amebiasis. Colon resection with enterostomy miraculously allowed him to survive. In comparison with the latter, who underwent more aggressive surgery and experienced more catastrophic complications, the former with conservative surgery had a smoother clinical result. Thus, conservative operation for colon perforation due to amebiasis is recommended. Besides, thanks to the alertness of doctors, the favorable age of the patients, the advent of new antiamebic and antimicrobial agents, excellent hyperalimentation, the great improvement in medical facilities and postoperative care, the two critical patients eventually survived after several operations, and had a better outcome as compared with the high mortality rate of 87.5% in our hospital 2 decades earlier.
authors.affiliation: Department of Surgery, National Taiwan University Hospital, Taipei, Republic of China.
authors.forename: Y B
authors.initials: YB
authors.lastname: Hsu
authors.forename: F M
authors.initials: FM
authors.lastname: Chen
authors.forename: P H
authors.initials: PH
authors.lastname: Lee
authors.forename: S C
authors.initials: SC
authors.lastname: Yu
authors.forename: K M
authors.initials: KM
authors.lastname: Chen
authors.forename: Y T
authors.initials: YT
authors.lastname: Yao
authors.forename: H C
authors.initials: HC
authors.lastname: Hsu
mesh_terms: D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D003108:Colonic Diseases / Q000209:etiology / Q000601:surgery; D003131:Combined Modality Therapy; D004404:Dysentery, Amebic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery; D008101:Liver Abscess, Amebic / Q000150:complications; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D000981:Antiprotozoal Agents