title: Synthesis of oligosaccharide substrates for N-linked glycoprotein processing enzymes.
abstract: The stereoselective syntheses of one pentasaccharide and one tetrasaccharide containing the Glc-alpha-(1-->3)-Man-alpha moiety as their terminal unit, as well as one tetrasaccharide and one trisaccharide containing the Man-alpha-(1-->2)-Man-alpha terminal unit were accomplished through the utilization of two key glycosyl donors, namely, 4-pentenyl 3-O-acetyl-2,4,6-tri-O-benzyl-alpha-D-mannopyranoside and ethyl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-alpha-D-mannopyranoside.
authors.affiliation: Department of Gynecologic Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
authors.forename: R K
authors.initials: RK
authors.lastname: Jain
authors.forename: X G
authors.initials: XG
authors.lastname: Liu
authors.forename: S R
authors.initials: SR
authors.lastname: Oruganti
authors.forename: E V
authors.initials: EV
authors.lastname: Chandrasekaran
authors.forename: K L
authors.initials: KL
authors.lastname: Matta
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D006023:Glycoproteins / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008362:Mannosides / Q000138:chemical synthesis* / Q000737:chemistry; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006023:Glycoproteins; D008362:Mannosides; D009844:Oligosaccharides; D006026:Glycoside Hydrolases