Identification of a member of mouse semaphorin family.
Grasshopper semaphorin I (Sema I) and its related proteins, chick collapsin and mouse Sema III contribute to the axon guidance by their repellent actions [5,9,12]. We have identified a member of semaphorin gene family from the mouse brain and named it M-Sema F. The N-terminal encodes a semaphorin domain that is similar between Sema I-III [6] followed by a single putative immunoglobulin-like domain, a transmembrane domain, and a proline-rich intracellular domain. M-Sema F mRNA is expressed widely in the nervous tissues during development. These suggest that M-Sema F is a transmembrane member of the semaphorin family of the vertebrate which may function in the developing neuronal network.
Inagaki
S
S
Department of Laboratory Sciences, School of Allied Health Sciences, Osaka University Faculty of Medicine, Japan.
Furuyama
T
T
Iwahashi
Y
Y
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D003001:Cloning, Molecular; D005260:Female; D015870:Gene Expression; D006023:Glycoproteins / Q000737:chemistry* / Q000235:genetics*; D017403:In Situ Hybridization; D051379:Mice; D008969:Molecular Sequence Data; D009414:Nerve Growth Factors / Q000737:chemistry* / Q000235:genetics*; D011247:Pregnancy; D040121:Semaphorin-3A
D006023:Glycoproteins; D009414:Nerve Growth Factors; D040121:Semaphorin-3A