Predicting renal disease in type I diabetics: smoke and fire or smoke and mirrors?
This review has demonstrated that DN is common and can occur in one-third to one-half of IDDM patients. DN has a strong metabolic component, but there is also a component of genetic susceptibility. Persistent microalbuminuria is currently the most convenient and reliable predictor of nephropathy. Finally, Na/LiCTT, an experimental (and not yet commercially available) blood test, is felt to be a predictor of familial susceptibility to hypertension, and may be a marker of the risk of nephropathy in IDDM.
Lenhard
M J
MJ
Diabetes and Metabolic Diseases Center, Medical Center of Delaware, Newark, USA.
D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000209:etiology*; D004198:Disease Susceptibility; D005819:Genetic Markers; D006801:Humans; D012307:Risk Factors
D005819:Genetic Markers