title: A case of nodular fasciitis arising in the auricle.
abstract: Nudular fasciitis is an uncommon benign proliferative lesion in the head and neck, and is extremely rare in the auricle. A case of nodular fasciitis arising in the auricle of 53-year-old man is reported by immunohistochemical and electron microscopical studies. Initially, he had noticed a small painless nodule on the posterior side of right auricle, and it grew up rapidly in size over 2 months. A biopsy revealed nodular fasciitis. This lesion was resected totally with the auricular cartilage. Histological examination revealed proliferation of spindle-shaped cells and immunohistochemical-positive staining was observed with actin, and focally positive staining was seen with vimentin. Electron microscopically some tumor cells contained dilated rough endoplasmic reticulum and myofilament-like bundles in cytoplasm.
authors.affiliation: Departments of Head and Neck Surgery, Chiba Cancer Center Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Katahashi
authors.forename: F
authors.initials: F
authors.lastname: Shimada
authors.forename: K
authors.initials: K
authors.lastname: Omura
authors.forename: S
authors.initials: S
authors.lastname: Makino
authors.forename: O
authors.initials: O
authors.lastname: Matsuzaki
mesh_terms: D000199:Actins / Q000032:analysis; D001706:Biopsy; D002455:Cell Division / Q000502:physiology; D004427:Ear Diseases / Q000473:pathology*; D004431:Ear, External / Q000473:pathology*; D005208:Fasciitis / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014746:Vimentin