Expression of laminin in vestibular ganglia and nerves in herpes simplex virus infectious chick embryo.
The expression of laminin in the vestibular ganglia and nerves in herpes simplex virus I (HSV-I) infectious chick embryos was examined by immuno-histochemistry. In 9-day-old normal chick embryos, the surface of the vestibular ganglion cells and the vestibular nerves were labelled with laminin, while, in HSV-I infectious chick embryos, the staining of laminin in the vestibular ganglia and nerves was very weak. These results suggest that HSV-I injures vestibular ganglia and nerves, and that laminin is a good marker of the degeneration and innervation of developing vestibular nerves.
Yamashita
H
H
Department of Otolarygology, Yamagichi University School of Medicine, Japan.
Tahara
T
T
Shimogori
H
H
Takahashi
M
M
D000818:Animals; D002642:Chick Embryo; D017950:Ganglia, Sensory / Q000737:chemistry* / Q000196:embryology; D006561:Herpes Simplex / Q000196:embryology / Q000378:metabolism*; D007150:Immunohistochemistry; D007797:Laminin / Q000032:analysis*; D014725:Vestibular Nerve / Q000737:chemistry* / Q000196:embryology
D007797:Laminin