Measurement of epidermal moisture content by magnetic resonance imaging: assessment of a hydration cream.
The moisture content of the epidermis was measured by magnetic resonance imaging (MRI), using transverse relaxation time. The spatial resolution was 86 microns, allowing a quantitative, accurate and localized determination of variations in epidermal hydration. The wrists of 15 volunteers were studied before and after application of a hydration cream. Results showed an increase of 15% of epidermal T2 after application of the cream. Moisture content curves varied according to different degrees of skin dryness. This study demonstrates that MRI is a useful tool in evaluation of epidermal hydration.
Franconi
F
F
Laboratoire de Biophysique Cellulaire et Résonance Magnétique Nucléaire, Faculté de Médecine, Tours, France.
Akoka
S
S
Guesnet
J
J
Baret
J M
JM
Dersigny
D
D
Breda
B
B
Muller
C
C
Beau
P
P
D000279:Administration, Cutaneous; D000328:Adult; D001834:Body Water; D003358:Cosmetics / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D012867:Skin / Q000187:drug effects; D014953:Wrist
D003358:Cosmetics