In vitro and in vivo study on the conversion of allopurinol and pyrazinamide.
Nasako
Y
Y
Third Department of Internal Medicine, Hyogo College of Medicine, Japan.
Yamamoto
T
T
Moriwaki
Y
Y
Takahashi
S
S
Tsutsumi
Z
Z
Hada
T
T
Higashino
K
K
D042931:Aldehyde Oxidase; D000445:Aldehyde Oxidoreductases / Q000378:metabolism*; D000493:Allopurinol / Q000378:metabolism*; D000818:Animals; D001711:Biotransformation; D008099:Liver / Q000201:enzymology*; D008297:Male; D010084:Oxidation-Reduction; D010117:Oxypurinol / Q000097:blood; D011718:Pyrazinamide / Q000031:analogs & derivatives / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D014227:Triazines / Q000494:pharmacology; D014968:Xanthine Dehydrogenase / Q000037:antagonists & inhibitors; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors
D014227:Triazines; C032191:5-hydroxypyrazinamide; D011718:Pyrazinamide; C072977:BOF 4272; D000493:Allopurinol; D014968:Xanthine Dehydrogenase; D014969:Xanthine Oxidase; D000445:Aldehyde Oxidoreductases; D042931:Aldehyde Oxidase; D010117:Oxypurinol