Disseminated Geotrichum infection.
Intensive chemotherapy has prolonged survival in cancer patients. Unfortunately it has also predisposed them to unusual infections because of their immunocompromised state. We report a case of fungal septicaemia caused by Geotrichum candidum, an imperfect yeast of low virulence in a young girl with acute lymphoblastic leukaemia. It was successfully treated with amphotericin B. The morphological characteristics of this fungus leading to its identification are described.
Ng
K P
KP
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur.
Soo-Hoo
T S
TS
Koh
M T
MT
Kwan
P W
PW
D000666:Amphotericin B / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D016469:Fungemia / Q000188:drug therapy; D005847:Geotrichosis / Q000097:blood* / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*
D000970:Antineoplastic Agents; D000666:Amphotericin B