title: Longitudinal evolution of prefrontal leucotomy in Tourette's syndrome.
abstract: We report the case of a 69-year-old man with severe Tourette's syndrome (TS) who underwent a bilateral prefrontal leucotomy at the age of 29 years to alleviate coprolalia, copropraxia, and obsessive-compulsive disorder. No improvement was observed during the 5 years after the leucotomy. Tics and associated behavioral abnormalities disappeared thereafter, to recur at age 67. Long-term follow-up of single cases can help to estimate the role of neurosurgery in the treatment of TS.
authors.affiliation: Department of Neurology, Sant Pau Hospital, Autonomous University of Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Kulisevsky
authors.forename: M L
authors.initials: ML
authors.lastname: Berthier
authors.forename: A
authors.initials: A
authors.lastname: Avila
mesh_terms: D000368:Aged; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D017397:Prefrontal Cortex / Q000503:physiopathology / Q000601:surgery*; D011612:Psychosurgery; D005879:Tourette Syndrome / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome