Epithelial planar polarity in the developing Drosophila eye.
Experiments with the insect ectoderm have suggested that planar polarity in epithelia results from the local orientation of cells to the slope of a gradient of positional information. Here we show that planar polarity in the Drosophila eye is inverted when the morphogenetic wave that sweeps through the presumptive retinal epithelium is induced to move in the reverse direction. We suggest that the movement of the morphogenetic wave may be causal in establishing the planar polarity of this epithelium.
Wehrli
M
M
Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York 10032, USA.
Tomlinson
A
A
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D016764:Cell Polarity; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D004475:Ectoderm / Q000502:physiology; D005455:Fluorescent Antibody Technique; D017344:Genes, Insect; D053823:Hedgehog Proteins; D008954:Models, Biological; D009024:Morphogenesis / Q000235:genetics / Q000502:physiology; D017956:Photoreceptor Cells, Invertebrate / Q000196:embryology*; D010857:Pigment Epithelium of Eye / Q000196:embryology*; D011506:Proteins / Q000502:physiology; D015398:Signal Transduction
D029721:Drosophila Proteins; D053823:Hedgehog Proteins; D011506:Proteins; C077245:hh protein, Drosophila