title: The need for ventilatory support during bystander CPR.
abstract: OBJECTIVE
  To compare CPR with chest compressions plus ventilatory support (CC+V) and chest compressions alone (CC).
  
  
  METHODS
  Prospective, randomized study.
  
  
  METHODS
  Research laboratory.
  
  
  METHODS
  After 2 minutes of ventricular fibrillation, 18 domestic swine (20 to 35 kg) were treated first with CC or CC+V for 10 minutes, then with standard advanced cardiac life support.
  
  
  RESULTS
  Hemodynamics, survival, and neurologic outcome were determined. All 8 swine subjected to CC+V and all 10 subjected to CC showed return of spontaneous circulation. One animal in each group died within 1 hour. Seven of 8 animals in the CC+V group survived for 24 and 48 hours, compared with 9 of 10 CC animals at 24 hours and 8 of 10 at 48 hours. All 48-hour survivors were neurologically normal.
  
  
  CONCLUSIONS
  In this experimental model of bystander CPR, we could not detect a difference in hemodynamics, 48-hour survival, or neurologic outcome when CPR was applied with and without ventilatory support.
authors.affiliation: Department of Pediatrics, College of Agriculture, University of Arizona, Tucson, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Berg
authors.forename: D
authors.initials: D
authors.lastname: Wilcoxson
authors.forename: R W
authors.initials: RW
authors.lastname: Hilwig
authors.forename: K B
authors.initials: KB
authors.lastname: Kern
authors.forename: A B
authors.initials: AB
authors.lastname: Sanders
authors.forename: C W
authors.initials: CW
authors.lastname: Otto
authors.forename: D K
authors.initials: DK
authors.lastname: Eklund
authors.forename: G A
authors.initials: GA
authors.lastname: Ewy
mesh_terms: D000818:Animals; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D004195:Disease Models, Animal; D004632:Emergency Medical Services; D006336:Heart Massage / Q000379:methods*; D006439:Hemodynamics; D010100:Oxygen / Q000097:blood; D011897:Random Allocation; D016019:Survival Analysis; D013552:Swine; D013997:Time Factors; D016896:Treatment Outcome; D014693:Ventricular Fibrillation / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
chemical_list: D010100:Oxygen