Studies with wortmannin indicate that insulin stimulation of lipogenesis involves multiple signalling pathways.
Moule
S K
SK
Dept. of Biochemistry, School of Medical Sciences, University Walk, Bristol, U.K.
Edgell
N J
NJ
Welsh
G I
GI
Diggle
T A
TA
Proud
C G
CG
Denton
R M
RM
D000103:Acetyl-CoA Carboxylase / Q000378:metabolism; D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism*; D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism*; D000730:Androstadienes / Q000494:pharmacology*; D000818:Animals; D002478:Cells, Cultured; D004822:Epididymis; D005227:Fatty Acids / Q000096:biosynthesis*; D005947:Glucose / Q000378:metabolism; D007328:Insulin / Q000494:pharmacology*; D007329:Insulin Antagonists / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects*; D000077191:Wortmannin
D000730:Androstadienes; D005227:Fatty Acids; D007328:Insulin; D007329:Insulin Antagonists; D011768:Pyruvate Dehydrogenase Complex; D000103:Acetyl-CoA Carboxylase; D005947:Glucose; D000077191:Wortmannin