title: First clinical experience with Excimer assisted high flow bypass surgery of the brain.
abstract: A new type of revascularization of the brain is used in patients with brain ischaemia, caused by an occlusion of one or both internal carotid arteries, and in patients in whom the internal carotid artery has been deliberately occluded for the treatment of a giant aneurysm of the internal carotid artery. A so-called high flow extra-intracranial bypass operation is performed. An arterial or venous transplant is interposed between a branch of the external carotid artery or the external carotid artery itself and the intracranial portion of the internal carotid artery. The anastomosis with the intracranial portion of the internal carotid artery is made without temporary occlusion of the recipient artery and with the aid of the newly developed Excimer laser assisted anastomosis technique. The results of animal experiments and of a clinical series of 9 patients are reported.
authors.affiliation: Department of Neurosurgery, University Hospital, Utrecht, The Netherlands.
authors.forename: C A
authors.initials: CA
authors.lastname: Tulleken
authors.forename: R M
authors.initials: RM
authors.lastname: Verdaasdonk
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation; D000818:Animals; D001158:Arteries / Q000637:transplantation; D001164:Arteriovenous Fistula / Q000473:pathology / Q000601:surgery; D002545:Brain Ischemia / Q000473:pathology / Q000601:surgery*; D002342:Carotid Artery, External / Q000473:pathology / Q000601:surgery; D002343:Carotid Artery, Internal / Q000473:pathology / Q000601:surgery; D016893:Carotid Stenosis / Q000473:pathology / Q000601:surgery*; D002533:Cerebral Angiography; D002548:Cerebral Revascularization / Q000295:instrumentation*; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000473:pathology / Q000601:surgery; D053685:Laser Therapy / Q000295:instrumentation*; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D014654:Vascular Patency / Q000502:physiology; D014680:Veins / Q000637:transplantation