The paranasal sinuses of patients with acute graft-versus-host disease.
OBJECTIVE
To determine whether patients who have acute graft-versus-host disease (AGVHD), are more likely to have radiographically abnormal paranasal sinuses after bone marrow transplantation than patients without AGVHD.


METHODS
This retrospective case-control study population comprised 45 adult allogeneic or matched unrelated donor patients who underwent bone marrow transplantation. Twenty-eight patients had AGVHD, and 17 patients did not. All patients had paranasal sinus imaging with either CT or plain films for evaluation of possible sinusitis after bone marrow transplantation. The severity of radiographic changes was measured with an objective scoring system based on mucosal findings.


RESULTS
An odds ratio revealed no association between AGVHD and the presence of radiographically abnormal sinuses.


CONCLUSIONS
The diagnosis of AGVHD should not complicate the radiographic evaluation of acute sinusitis after bone marrow transplantation.
Deutsch
J H
JH
Department of Radiology, Emory University School of Medicine, Atlanta, Ga 30322, USA.
Hudgins
P A
PA
Siegel
J L
JL
Peterman
S B
SB
Devine
S M
SM
York
R
R
Wingard
J R
JR
D000208:Acute Disease; D000328:Adult; D016026:Bone Marrow Transplantation / Q000276:immunology; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D005260:Female; D006086:Graft vs Host Disease / Q000000981:diagnostic imaging* / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010254:Paranasal Sinus Diseases / Q000000981:diagnostic imaging* / Q000276:immunology; D012189:Retrospective Studies; D012852:Sinusitis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed