[Hairy cell leukemia and its treatment with 2-chlorodeoxyadenosine (2-CdA)].
In the last years a great progress was observed in the treatment of hairy cell leukaemia due to the introduction of interferon-alfa, pentostatin and above all -2-CdA. Through the programmed death - apoptosis of the hairy lymphocytes 2-CdA causes after 1-2 courses of treatment complete remissions in about 85% of previously treated as well as untreated patients. In the majority of them there are no symptoms of minimal residual disease and probability of their cure is significant.
Pawelski
S
S
Instytutu Hematologii i Transfuzjologii w Warszawie.
D017209:Apoptosis / Q000187:drug effects; D017338:Cladribine / Q000627:therapeutic use*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000188:drug therapy*; D015649:Pentostatin / Q000627:therapeutic use; D012074:Remission Induction
D016898:Interferon-alpha; D015649:Pentostatin; D017338:Cladribine
Białaczka włochatokomórkowa i jej leczenie 2-chlorodeoksyadenozyna (2-CdA).