Adaptive evolution of color vision genes in higher primates.
The intron 4 sequences of the three polymorphic alleles at the X-linked color photo-pigment locus in the squirrel monkey and the marmoset reveal that the alleles in each species are exceptionally divergent. The data further suggest either that each triallelic system has arisen independently in these two New World monkey lineages, or that in each species at least seven deletions and insertions (14 in the two species) in intron 4 have been transferred and homogenized among the alleles by gene conversion or recombination. In either case, the alleles in each species apparently have persisted more than 5 million years and probably have been maintained by overdominant selection.
Shyue
S K
SK
Human Genetics Center, School of Public Health, University of Texas, Houston 77225, USA.
Hewett-Emmett
D
D
Sperling
H G
HG
Hunt
D M
DM
Bowmaker
J K
JK
Mollon
J D
JD
Li
W H
WH
D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D002144:Callithrix; D003118:Color Perception / Q000235:genetics*; D005136:Eye Proteins / Q000235:genetics*; D005785:Gene Conversion; D008040:Genetic Linkage; D006801:Humans; D007438:Introns; D008297:Male; D008969:Molecular Sequence Data; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D012168:Retinal Pigments / Q000235:genetics*; D017299:Rod Opsins; D012453:Saimiri; D017384:Sequence Deletion; D013045:Species Specificity; D014960:X Chromosome
D005136:Eye Proteins; D012168:Retinal Pigments; D017299:Rod Opsins; C095855:long-wavelength opsin; C095854:middle-wavelength opsin