Role of RpoS in survival of Yersinia enterocolitica to a variety of environmental stresses.
rpoS, a gene that encodes an alternative sigma factor (also known as katF), is critical for the ability of Yersinia enterocolitica grown at 37 degrees C, but not at 26 degrees C, to survive diverse environmental insults such as high temperature, hydrogen peroxide, osmolarity, and low pH. However, a Y. enterocolitica rpoS mutant was not affected in expression of inv or ail, invasion of tissue culture cells, or virulence in mice.
Badger
J L
JL
Department of Microbiology and Molecular Genetics, University of California, Los Angeles 90095, USA.
Miller
V L
VL
D018829:Adhesins, Bacterial; D000595:Amino Acid Sequence; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D001483:Base Sequence; D005260:Female; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial / Q000235:genetics; D006358:Hot Temperature; D006861:Hydrogen Peroxide / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D009154:Mutation; D009994:Osmolar Concentration; D017386:Sequence Homology, Amino Acid; D012808:Sigma Factor / Q000235:genetics / Q000502:physiology*; D014774:Virulence; D015008:Yersinia enterocolitica / Q000187:drug effects / Q000235:genetics / Q000254:growth & development* / Q000472:pathogenicity
D018829:Adhesins, Bacterial; C069712:Ail protein, Yersinia enterocolitica; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D012808:Sigma Factor; C069567:sigma factor KatF protein, Bacteria; C053476:invasin, Yersinia; D006861:Hydrogen Peroxide