title: Glucocorticoid receptor thiols and steroid-binding activity.
authors.affiliation: Steroid Hormones Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Simons
authors.forename: W B
authors.initials: WB
authors.lastname: Pratt
mesh_terms: D000345:Affinity Labels; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D002918:Chymotrypsin; D003545:Cysteine; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism*; D018841:HSP90 Heat-Shock Proteins / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008741:Methyl Methanesulfonate / Q000031:analogs & derivatives / Q000494:pharmacology; D008961:Models, Structural; D016297:Mutagenesis, Site-Directed; D010446:Peptide Fragments / Q000737:chemistry / Q000302:isolation & purification; D011487:Protein Conformation; D051381:Rats; D011965:Receptors, Glucocorticoid / Q000737:chemistry* / Q000378:metabolism*; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D013256:Steroids / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000032:analysis*; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D013879:Thioredoxins / Q000378:metabolism; D014357:Trypsin
chemical_list: D000345:Affinity Labels; D004268:DNA-Binding Proteins; D018841:HSP90 Heat-Shock Proteins; D010446:Peptide Fragments; D011965:Receptors, Glucocorticoid; D011994:Recombinant Proteins; D013256:Steroids; D013438:Sulfhydryl Compounds; D013439:Sulfhydryl Reagents; C014674:methyl methanethiosulfonate; D013879:Thioredoxins; D008741:Methyl Methanesulfonate; D002918:Chymotrypsin; D014357:Trypsin; D003545:Cysteine