title: Video-thoracic surgery for treatment of end-stage bullous emphysema and chronic obstructive pulmonary disease.
abstract: Surgical treatment of emphysema and chronic obstructive pulmonary disease (COPD) has received renewed attention because of advances in instrumentation and techniques. Our approach includes video-assisted thoracotomy, neodymium-Yag and KTP laser plication of emphysematous bullae, pulmonary resection using reinforced stapling, and pleurodesis: reduction pneumonoplasty. In a 9-month period, 28 patients (age 52 to 78, 23 men and 5 women) with end-stage disease underwent reduction pneumonoplasty. Oxygen therapy was required in 82 per cent, steroid therapy was used in 86 per cent, and the preoperative FEV1 averaged 0.68 +/- 0.05. The most severely diseased lung was determined by physical, chest film, and CT scan, and this lung had reduction pneumonoplasty. There were no hospital mortalities. Prolonged postoperative air leaks occurred in 42 per cent of patients. Postoperatively FEV1 was 0.91 +/- 0.35. Lung size (chest film) showed 21.6 per cent reduction in volume. Subjective improvement was noted in 78.6 per cent (22/28) of patients, and no patient reported worse symptoms. Half of the steroid-using patients required a reduced steroid dose or no steroid therapy, and 5/23 (21.7%) patients had reduced oxygen requirements. Reduction pneumonoplasty can improve the symptoms of severe emphysema and COPD. Our results with treatment of one lung suggest that further improvement may be anticipated by proceeding with surgery for the contralateral lung.
authors.affiliation: Department of Surgery, Western Medical Center, Anaheim, California, USA.
authors.forename: J
authors.initials: J
authors.lastname: Eugene
authors.forename: R A
authors.initials: RA
authors.lastname: Ott
authors.forename: H S
authors.initials: HS
authors.lastname: Gogia
authors.forename: C
authors.initials: C
authors.lastname: Dos Santos
authors.forename: R
authors.initials: R
authors.lastname: Zeit
authors.forename: R A
authors.initials: RA
authors.lastname: Kayaleh
mesh_terms: D000368:Aged; D004646:Emphysema / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008173:Lung Diseases, Obstructive / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018700:Pleurodesis; D011013:Pneumonectomy / Q000295:instrumentation / Q000379:methods*; D012129:Respiratory Function Tests; D013908:Thoracotomy; D014741:Video Recording