The distance between Escherichia coli genes is related to gene expression levels.
It is shown that the distance between Escherichia coli genes oriented in the same direction on the chromosome is positively correlated to the expression level of the downstream gene. It is suggested that this could be a strategy to avoid interference between ribosomes translating two different genes.
Eyre-Walker
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Department of Biological Sciences, Rutgers University, Piscataway, New Jersey 08855-1059, USA.
D003062:Codon; D016208:Databases, Factual; D004926:Escherichia coli / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics*; D005798:Genes, Bacterial; D014176:Protein Biosynthesis
D003062:Codon