Identity of the Escherichia coli cls and nov genes.
cls and nov mutants have similar increased sensitivities to novobiocin and reduced levels of cardiolipin, both of which can be corrected by plasmid-borne copies of either wild-type gene. A comparison of the DNA sequences of both genes further verifies their identity.
Tropp
B E
BE
Department of Chemistry and Biochemistry, Queens College CUNY, Flushing 11367, USA.
Ragolia
L
L
Xia
W
W
Dowhan
W
W
Milkman
R
R
Rudd
K E
KE
Ivanisević
R
R
Savić
D J
DJ
D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics*; D005816:Genetic Complementation Test; D005838:Genotype; D008565:Membrane Proteins; D009154:Mutation; D009675:Novobiocin / Q000494:pharmacology*; D010714:Phosphatidylethanolamines / Q000032:analysis; D010715:Phosphatidylglycerols / Q000032:analysis; D017855:Transferases (Other Substituted Phosphate Groups) / Q000235:genetics*
D008565:Membrane Proteins; D010714:Phosphatidylethanolamines; D010715:Phosphatidylglycerols; D009675:Novobiocin; D017855:Transferases (Other Substituted Phosphate Groups); C100091:cardiolipin synthetase