title: [Ceftriaxone vs. cefazolin in obstetrical surgical prevention].
abstract: The cesarean section is associated with a high incidence of puerperal infections. The antibiotic prophylaxis in obstetric surgery may reduce infectious complications, nevertheless antibiotic prophylaxis only has proved to be effective in women with risk factors for the occurrence of infection. We made a comparative study of the prophylactic efficacy of the ceftriaxone a single dose versus cefazolin three doses, in women with risk factor for infection. There were enrolled 100 patients, 50 in each group. Six percent of the ceftriaxone group patients developed puerperal infections while 12% of the cefazolin group women developed this complication. The statistic analysis don't show difference between the groups. We consider the single dose prophylactic schema is better because its application is easier, administration is safety and reduces the risk of adverse reactions.
authors.affiliation: Departamento de Infectología e Immunología, Instituto Nacional de Perinatología, México, D.F.
authors.forename: R
authors.initials: R
authors.lastname: Figueroa Damián
authors.forename: F J
authors.initials: FJ
authors.lastname: Ortíz Ibarra
authors.forename: V M
authors.initials: VM
authors.lastname: Labastida Domínguez
authors.forename: R
authors.initials: R
authors.lastname: Villagrana Zesati
authors.forename: C Q
authors.initials: CQ
authors.lastname: García Benítez
authors.forename: J L
authors.initials: JL
authors.lastname: Arredondo García
mesh_terms: D000293:Adolescent; D000328:Adult; D002437:Cefazolin / Q000008:administration & dosage / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011183:Postoperative Complications; D011247:Pregnancy; D011292:Premedication; D011645:Puerperal Infection / Q000517:prevention & control*; D012307:Risk Factors; D013997:Time Factors
chemical_list: D002443:Ceftriaxone; D002437:Cefazolin
vernacular_title: Ceftriaxona vs. cefazolina en la profilaxis quirúrgica obstétrica.