Determination of dihydropyrimidine dehydrogenase (DPD) in fibroblasts of a DPD deficient pediatric patient and family members using a polyclonal antibody to human DPD.
Diasio
R B
RB
Department of Pharmacology, University of Alabama at Birmingham 35294, USA.
Van Kuilenburg
A B
AB
Lu
Z
Z
Zhang
R
R
Van Lenthe
H
H
Bakker
H D
HD
Van Gennip
A H
AH
D000293:Adolescent; D000906:Antibodies; D002648:Child; D002675:Child, Preschool; D042943:Dihydrouracil Dehydrogenase (NADP); D004311:Double-Blind Method; D005260:Female; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D015151:Immunoblotting / Q000379:methods; D008297:Male; D009679:Nuclear Family; D010088:Oxidoreductases / Q000032:analysis* / Q000172:deficiency*; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000175:diagnosis* / Q000201:enzymology / Q000235:genetics*
D000906:Antibodies; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP)