Nucleotide sequence of a human genomic DNA fragment containing the PCNA pseudogene and its localization on chromosome 4.
A one kb human genomic DNA fragment, containing a processed pseudogene of a proliferating cell nuclear antigen (PCNA/DNA polymerase delta auxiliary protein), was isolated and sequenced. The PCNA pseudogene consisted of the 3' half of exon 4 and the 5' half of exon 5 of the PCNA gene, and shared 84% nucleotide homology with the human PCNA cDNA. The PCNA pseudogene was localized on human chromosome 4, based on data obtained from a panel of human-mouse hybrid cell lines.
Arimori
K
K
4th Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Koido
S
S
Yoshimura
S
S
Taniguchi
Y
Y
Arimori
S
S
Moriuchi
T
T
D000818:Animals; D001483:Base Sequence; D002894:Chromosomes, Human, Pair 4; D018076:DNA, Complementary; D015894:Genome, Human; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D018809:Proliferating Cell Nuclear Antigen / Q000235:genetics*; D011544:Pseudogenes; D051381:Rats; D012689:Sequence Homology, Nucleic Acid
D018076:DNA, Complementary; D018809:Proliferating Cell Nuclear Antigen