[Stationary distribution of enzymatic reaction intermediates in the microcirculatory system].
On base of date about structure of blood vessels and kinetic of enzymic reactions in vitro (in reactor with mix) on mathematical model we shown possible distribution of concentration of intermediates of enzymic reaction at nature conditions near in vivo of intact organism. It has non-line character and can explain some peculiarity of physiological processes. For example, maximum stationary concentration of intermediate is arrived in region of capillaries in case of authorizing of Frank-Starling's hypothesis. External influences, decreasing constant of Michaelis, can increase in vivo the effective stationary concentration of intermediate in region of capillaries and remove the maximum of concentration to arterioles.
Shlygin
V V
VV
Arnautov
L N
LN
D001160:Arterioles / Q000201:enzymology*; D002196:Capillaries / Q000201:enzymology*; D004730:Endothelium, Vascular / Q000201:enzymology; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008962:Models, Theoretical
D004798:Enzymes
O statsionarnom raspredelenii intermediatov fermentativnoĭ reaktsii v mikrotsirkuliarnom rusle.