title: Sterilization reversal: fertility results.
abstract: Fertility outcome following sterilization reversal by laparotomy was evaluated. We studied all sterilization reversals performed between January 1978 and December 1991; a total of 226 women were treated. Tubal anastomosis was performed according to the rules for microsurgery. The microsurgical technique comprised two main phases: preparation of the healthy tube segments and the anastomosis carried out on two layers. It was possible to study the subsequent fertility of 206 patients in all, as 20 patients were lost to follow-up (8.8%). Cumulative pregnancy rates were evaluated by life-table analysis. The overall intrauterine pregnancy rate, including births and miscarriages, was 69.9% (144 patients) after 2 years. The cumulative intrauterine pregnancy rate was 62% at 18 months. Analysis of the fertility results demonstrated that age was the most significant predictive factor. The cumulative intrauterine pregnancy rate at 2 years was 83.5% (61 cases) for patients < or = 33 years, 70% (35 cases) for patients aged 34-36 years, 62.5% (30 cases) for patients aged 37-39 years, and 51.4% (18 cases) for patients aged > or = 40 years. Even for patients aged approximately 40 years, microsurgical repermeabilization can be retained as the first choice rather than in-vitro fertilization.
authors.affiliation: Service de Chirurgie Gynecologique, Clinique Universitaire Baudelocque, C.H.U. Cochin Port-Royal, Paris, France.
authors.forename: J B
authors.initials: JB
authors.lastname: Dubuisson
authors.forename: C
authors.initials: C
authors.lastname: Chapron
authors.forename: C
authors.initials: C
authors.lastname: Nos
authors.forename: P
authors.initials: P
authors.lastname: Morice
authors.forename: F X
authors.initials: FX
authors.lastname: Aubriot
authors.forename: P
authors.initials: P
authors.lastname: Garnier
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D005298:Fertility; D006801:Humans; D007813:Laparotomy; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D011247:Pregnancy; D011379:Prognosis; D013243:Sterilization Reversal / Q000379:methods*; D013246:Sterilization, Tubal / Q000379:methods; D013997:Time Factors