Isolation and characterization of mutations in the mouse APRT gene that encode functional enzymes with resistance to toxic adenine analogs.
Khattar
N H
NH
Department of Microbiology and Immunology, University of Kentucky, Lexington 40536, USA.
Jennings
C D
CD
Walker
K A
KA
Turker
M S
MS
D015075:2-Aminopurine / Q000031:analogs & derivatives* / Q000633:toxicity; D000225:Adenine / Q000031:analogs & derivatives* / Q000633:toxicity*; D000228:Adenine Phosphoribosyltransferase / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D000818:Animals; D018236:Carcinoma, Embryonal; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D007700:Kinetics; D051379:Mice; D016296:Mutagenesis; D014407:Tumor Cells, Cultured; D014466:Ultraviolet Rays
D015075:2-Aminopurine; C007300:2,6-diaminopurine; D005020:Ethyl Methanesulfonate; D000228:Adenine Phosphoribosyltransferase; D000225:Adenine