title: Effect of toluene extraction on Biomer surface: I. ESCA, ATR/FTIR, contact angle analysis and biological properties.
abstract: Biomer is a poly(ether-urethane-urea) block copolymer widely used as biomedical devices. Extraction process of this polymer has purified its surface of low molecular weight polyurethane chains and Santowhite Powder additive. ESCA and ATR/FTIR have suggested a homogenization of the polymer by enrichment of the first layers with poly(aminomethacrylate) additive after extraction. Therefore, the surface of the extracted Biomer exhibits a different wettability and biological response. The treatment causes a significant decrease in fibronectin adsorption and induces a reduction in Staphylococcus aureus adhesion.
authors.affiliation: Group of Applied Physics, University of Geneva, Switzerland.
authors.forename: N
authors.initials: N
authors.lastname: Nurdin
authors.forename: P
authors.initials: P
authors.lastname: François
authors.forename: A
authors.initials: A
authors.lastname: Magnani
authors.forename: N
authors.initials: N
authors.lastname: Xanthopoulos
authors.forename: H J
authors.initials: HJ
authors.lastname: Mathieu
authors.forename: R
authors.initials: R
authors.lastname: Barbucci
authors.forename: P
authors.initials: P
authors.lastname: Vaudaux
authors.forename: P
authors.initials: P
authors.lastname: Descouts
mesh_terms: D000327:Adsorption; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D001422:Bacterial Adhesion / Q000502:physiology*; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism* / Q000592:standards; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D004577:Electron Probe Microanalysis; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D008970:Molecular Weight; D011140:Polyurethanes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000378:metabolism; D014050:Toluene
chemical_list: D000975:Antioxidants; D001672:Biocompatible Materials; D005353:Fibronectins; D011140:Polyurethanes; D002084:Butylated Hydroxytoluene; D014050:Toluene; C031892:biomer; C030594:Santowhite powder