title: [Role of absorptiometry in the evaluation of bone tissue status in women with primary hyperprolactinemia].
abstract: Mineral density of bone tissue was assessed in 22 patients with oligoamenorrhea caused by primary hyperprolactinemia. Primary hyperprolactinemia in the presence of pituitary adenoma was diagnosed in 8 patients, primary functional form of the disease in 14. Fifteen healthy women were controls. Blood serum concentrations of prolactin, estradiol, progesterone, testosterone, hydrocortisone, LH, and FSH were measured. Bone tissue mineral density was assessed by monophoton absorptiometry in the distal portion of the radial bone at sites 1/3 and 1/20 of its length two times with one-year interval. Abnormal loss of mineral density of bone tissue in 1/3 site was detected in 4 out of 14 patients with functional and in 3 out of 8 patients with tumorous hyperprolactinemia, in site 1/20 in 9 out of 14 and in 8, respectively. Reduction of mineral density of bone tissue was associated with pronounced hormonal imbalance in all the patients with accelerated loss of bone tissue, no matter what form of primary hyperprolactinemia they developed.
authors.forename: M M
authors.initials: MM
authors.lastname: Baĭdak
mesh_terms: D015502:Absorptiometry, Photon; D000236:Adenoma / Q000150:complications; D000328:Adult; D015519:Bone Density; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006966:Hyperprolactinemia / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D007986:Luteinizing Hormone / Q000097:blood; D010911:Pituitary Neoplasms / Q000150:complications; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D006854:Hydrocortisone
vernacular_title: Rol' absorbtsiometricheskikh issledovaniĭ v otsenke sostoianiia kostnoĭ tkani u zhenshchin s pervichnoĭ giperprolaktinemieĭ.