title: [Retrograde intravenous perfusion as ultima ratio in potential amputation patients with peripheral arterial occlusive disease].
abstract: In 21 patients with critical ischemia and/or inflammation of the leg facing possible amputation, retrograde intravenous perfusion (RVP) was used to administer fibrinolytics, vasodilators and antibiotics. Amputation was avoided in 15 patients. In 4 patients, RVP was interrupted due to unsuitable veins for putting in cannulas. After introducing a 3-in-1-Block (Winnie) for analgesia, 7 courses of treatment at least were reached before unbearable pain became a reason for stopping therapy. RVP should, therefore, be considered as the last resort in the treatment of critical ischemia and/or inflammation of the leg of patients facing possible amputation.
authors.affiliation: Klinik für Innere Medizin III, Klinikums der Friedrich Schiller Universität Jena.
authors.forename: G
authors.initials: G
authors.lastname: Pöhlmann
authors.forename: D
authors.initials: D
authors.lastname: Reinhardt
authors.forename: G
authors.initials: G
authors.lastname: Grohmann
authors.forename: G
authors.initials: G
authors.lastname: Eidner
authors.forename: S
authors.initials: S
authors.lastname: Müller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000527:Alprostadil / Q000008:administration & dosage; D000900:Anti-Bacterial Agents; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007511:Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins / Q000008:administration & dosage; D016879:Salvage Therapy; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D011994:Recombinant Proteins; D014665:Vasodilator Agents; D006493:Heparin; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator; D000527:Alprostadil
vernacular_title: Retrograde intravenöse Perfusion als ultima ratio bei amputationsgefährdeten Patienten mit einer peripheren arteriellen Verschlusskrankheit.