title: Complete sequence of the bithorax complex of Drosophila.
abstract: The bithorax complex (BX-C) of Drosophila, one of two complexes that act as master regulators of the body plan of the fly, is included within a sequence of 338,234 bp (SEQ89E). This paper presents the strategy used in sequencing SEQ89E and an analysis of its open reading frames. The BX-C sequence (BXCALL) contains 314,895 bp obtained by deletion of putative genes that are located at each end of SEQ89E and appear to be functionally unrelated to the BX-C. Only 1.4% of BXCALL codes for the three homeodomain-containing proteins of the complex. Principal findings include a putative ABD-A protein (ABD-AII) larger than a previously known ABD-A protein and a putative glucose transporter-like gene (1521 bp) located at or near the bithoraxoid (bxd), infra-abdominal-2 (iab-2) boundary on the opposite strand relative to that of the homeobox-containing genes.
authors.affiliation: Human Genome Center, Lawrence Berkeley Laboratory, Berkeley, CA 94720, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Martin
authors.forename: C A
authors.initials: CA
authors.lastname: Mayeda
authors.forename: C A
authors.initials: CA
authors.lastname: Davis
authors.forename: C L
authors.initials: CL
authors.lastname: Ericsson
authors.forename: J D
authors.initials: JD
authors.lastname: Knafels
authors.forename: D R
authors.initials: DR
authors.lastname: Mathog
authors.forename: S E
authors.initials: SE
authors.lastname: Celniker
authors.forename: E B
authors.initials: EB
authors.lastname: Lewis
authors.forename: M J
authors.initials: MJ
authors.lastname: Palazzolo
mesh_terms: D000818:Animals; D003062:Codon; D004330:Drosophila / Q000235:genetics*; D017344:Genes, Insect; D007438:Introns; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D015183:Restriction Mapping
chemical_list: D003062:Codon