title: Management of sacral and perineal defects following abdominoperineal resection and radiation with transpelvic muscle flaps.
abstract: OBJECTIVE
  In this study we present our experience with treating persistent sacral and perineal defects secondary to radiation and abdominoperineal resection with or without sacrectomy.
  
  
  METHODS
  Fifteen consecutive patients were treated with an inferiorly based transpelvic rectus abdominis muscle or musculocutaneous flap.
  
  
  RESULTS
  Fourteen of the 15 patients achieved healing, and 7 patients had no complications. The remaining eight patients required one or more operative debridements and/or prolonged wound care to accomplish a healed wound. Our technique for the dissection and insetting of the transpelvic muscle flap is presented.
  
  
  CONCLUSIONS
  The difficult postirradiated perineal and sacral wounds can be healed with persistent surgical attention to adequate debridement, control of infections, and a well-vascularized muscle flap. The most satisfying aspects for patients are the discontinuance of foul-smelling discharge, discontinuation of multiple, daily dressing changes, and reduction in the degree of chronic pain.
authors.affiliation: Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Loessin
authors.forename: N B
authors.initials: NB
authors.lastname: Meland
authors.forename: R M
authors.initials: RM
authors.lastname: Devine
authors.forename: B G
authors.initials: BG
authors.lastname: Wolff
authors.forename: H
authors.initials: H
authors.lastname: Nelson
authors.forename: H
authors.initials: H
authors.lastname: Zincke
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000601:surgery; D007414:Intestinal Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010502:Perineum / Q000528:radiation effects / Q000601:surgery*; D011183:Postoperative Complications / Q000601:surgery; D011832:Radiation Injuries / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects; D012086:Reoperation; D012445:Sacrococcygeal Region / Q000528:radiation effects / Q000601:surgery*; D013524:Surgical Flaps / Q000379:methods*; D014945:Wound Healing