title: [Determination of beta-phenyllactic acid in rat plasma by derivatization capillary gas chromatography (DCGC)].
abstract: The determination of beta-phenyllactic acid (PLA) in rat plasma by derivatization capillary gas chromatography is described. Quantitation was affected by 63Ni-electron capture detector after separation with a SE-54 quartz capillary chromatographic column. Calibration curves were linear within the range of 1.6-9.6 micrograms.ml-1. The limit of detection of PLA was considered to be 0.5 microgram.ml-1. PLA was extracted from plasma with ethyl acetate (rat plasma 0.1 ml). The recovery from plasma was high and the mean value was 98.11 +/- 3.81 (s)%, their within day and between day relative standard deviations were 5.13% and 5.99% respectively.
authors.affiliation: Department of Instrumental Analysis Centre, School of Pharmacy, Shanghai Medical University.
authors.forename: G Q
authors.initials: GQ
authors.lastname: Mo
authors.forename: X M
authors.initials: XM
authors.lastname: Zhang
authors.forename: W B
authors.initials: WB
authors.lastname: Cheng
authors.forename: D
authors.initials: D
authors.lastname: Li
authors.forename: X Y
authors.initials: XY
authors.lastname: Yang
mesh_terms: D000818:Animals; D002849:Chromatography, Gas / Q000379:methods; D007773:Lactates / Q000097:blood*; D051381:Rats
chemical_list: D007773:Lactates; C017648:3-phenyllactic acid