title: Cytomegalovirus infection in renal transplantation.
abstract: Three case reports of Cytomegalovirus (CMV) disease in seronegative renal transplant recipients of seropositive donor kidneys are presented. Clinicians need to have a high index of suspicion for CMV disease in such patients. Early diagnosis and treatment are essential to decrease morbidity and mortality. Prophylaxis with antiviral and/or CMV-hyperimmunoglobulin may decrease the incidence of serious infection.
authors.affiliation: Renal Unit, Nottingham City Hospital, England.
authors.forename: E N
authors.initials: EN
authors.lastname: Barton
authors.forename: K M
authors.initials: KM
authors.lastname: Rigg
authors.forename: A G
authors.initials: AG
authors.lastname: Morgan
authors.forename: R P
authors.initials: RP
authors.lastname: Burden
mesh_terms: D000293:Adolescent; D000328:Adult; D003428:Cross Infection / Q000097:blood / Q000188:drug therapy / Q000635:transmission*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000188:drug therapy / Q000635:transmission*; D003937:Diagnosis, Differential; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male
chemical_list: D015774:Ganciclovir