Bowel inflammation in anterior uveitis and spondyloarthropathy.
OBJECTIVE
To assess the possible involvement of the bowel in the spectrum of anterior uveitis (AU).


METHODS
Ileocolonoscopy and histology studies were performed on 27 patients with AU.


RESULTS
Patients with AU had a higher incidence of chronic intestinal inflammation (CII) than controls. CII was present in AU regardless of HLA-B27 status, sacroiliitis or NSAID intake, and was more prevalent in uveitis with high recurrence.


CONCLUSIONS
Bowl inflammation ia a component of the spectrum of AU. This finding supports a HIL-B27 independent common pathogenic link between AU and spondyloarthropathy.
Bañares
A A
AA
Department of Rheumatology, Hospital Universitario, San Carlos, Madrid, Spain.
Jover
J A
JA
Fernández-Gutiérrez
B
B
Benítez del Castillo
J M
JM
García
J
J
González
F
F
López
J A
JA
Hernández-García
C
C
D000293:Adolescent; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications; D001706:Biopsy; D004751:Enteritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005260:Female; D015796:HLA-B27 Antigen / Q000032:analysis; D006801:Humans; D007422:Intestines / Q000473:pathology; D008297:Male; D012044:Regression Analysis; D012446:Sacroiliac Joint; D012727:Sex Characteristics; D013122:Spinal Diseases / Q000150:complications*; D014605:Uveitis / Q000150:complications*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D015796:HLA-B27 Antigen