Portable current stimulator for transdermal iontophoretic drug delivery.
A pulse stimulator was designed. It is small sized (3 x 2 cm printed circuit board) and battery-powered (185 microA total static current). The current intensity and pulse duration of this device can be continuously varied. Preliminary trials of lidocaine show that this device is usable for transdermal drug delivery and may be valuable for portable applications.
Jaw
F S
FS
Center for Biomedical Engineering, National Taiwan University, Taipei, ROC.
Wang
C Y
CY
Huang
Y Y
YY
D000279:Administration, Cutaneous; D000818:Animals; D007478:Iontophoresis / Q000295:instrumentation* / Q000379:methods; D008012:Lidocaine / Q000008:administration & dosage* / Q000493:pharmacokinetics; D011817:Rabbits; D013997:Time Factors
D008012:Lidocaine