Changes in daily life experience associated with clinical improvement in depression.
Changes in depressed outpatients' experience of daily activities after 6 weeks of antidepressant treatment were assessed with the experience sampling method (ESM). On the sickness impact profile, treatment responders (HAM-D < or = 7, n = 12) improved more than nonresponders (n = 9) in the domains of household chores, leisure and social activities. On ESM measures completed 10 x each day for 6 days pre- and posttreatment, responders showed greater increases in time spent in chores and greater decreases in passive leisure time than nonresponders. Responders showed greater increases in positive affect and greater decreases in negative affect during all activities. Thus, ESM provides quantitative evidence of changes in real life time use and subjective experience accompanying clinical improvement.
Barge-Schaapveld
D Q
DQ
Department of Psychiatry and Neuropsychology, University of Limburg, Maastricht, The Netherlands.
Nicolson
N A
NA
van der Hoop
R G
RG
De Vries
M W
MW
D000203:Activities of Daily Living / Q000523:psychology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000639:Amitriptyline / Q000009:adverse effects / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D010555:Personality Inventory; D011788:Quality of Life; D016037:Single-Blind Method
D005473:Fluoxetine; D000639:Amitriptyline