[The effect of hydrodynamic conditions on the interferon-synthesizing activity of swine splenocytes in the production of alpha-interferon].
Parameters of physical constituents of the agitation process and mass-exchange characteristics of the suggested bioreactor for suspension cultivation of pig splenocytes are determined. The effect of hydrodynamic conditions on viability and interferon-synthesizing activity of cells in production of alpha-interferon of pigs has been studied. The relation existing between interferonogenesis processes proceeding under suspension and under stationary biosynthesis has been analyzed by the pair correlation method.
Dumanskiĭ
V D
VD
Povodzinskiĭ
V N
VN
Karlash
Iu V
IuV
Ivanenko
V K
VK
Seleznev
A V
AV
Tsygankov
S P
SP
Kishko
Ia G
IaG
D000818:Animals; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D016898:Interferon-alpha / Q000096:biosynthesis*; D008433:Mathematics; D013154:Spleen / Q000166:cytology / Q000378:metabolism*; D013552:Swine
D016898:Interferon-alpha
Vliianie gidrodinamicheskikh usloviĭ na interferonsinteziruiushchuiu aktivnost' splenotsitov svineĭ pri poluchenii al'fa-interferona.