title: Tyrosine phosphorylation accompanying the cellularization of the syncytial blastoderm of Drosophila.
abstract: At an early stage in embryogenesis, the Drosophila blastoderm is a syncytium in which approximately 6000 nuclei align under the plasma membrane. During the interphase of nuclear cycle 14, a wave of membrane formation descends from the blastoderm surface to enclose each nucleus in an intact cell membrane. We show by immunofluorescence microscopy that the membrane-formation process is closely accompanied in space and time by a wave of tyrosine phosphorylation, suggesting that one or more tyrosine kinases and phosphatases are active in the process.
authors.affiliation: Department of Biology, University of California, San Diego, La Jolla 92093-0322, USA.
authors.forename: D
authors.initials: D
authors.lastname: Loncar
authors.forename: S J
authors.initials: SJ
authors.lastname: Singer
mesh_terms: D000818:Animals; D001756:Blastoderm / Q000166:cytology* / Q000378:metabolism; D004331:Drosophila melanogaster / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D010766:Phosphorylation; D014443:Tyrosine / Q000378:metabolism*
chemical_list: D014443:Tyrosine