title: Spinal anaesthesia for transurethral surgery: comparison of 2% lignocaine with hyperbaric 0.5% bupivacaine.
abstract: We have compared 2% lignocaine 3.5 ml with 0.5% hyperbaric bupivacaine 3 ml in a randomized, double-blind study in 30 patients undergoing subarachnoid anaesthesia for transurethral surgery. A sensory level of T10 was produced more quickly (P = 0.0001) and maximum height reached sooner (P = 0.0002) with lignocaine, although there was a greater reduction in systolic arterial pressure (P = 0.03) and a trend towards slower heart rates (P = 0.056). Return of full sensory and motor function occurred earlier with lignocaine (P = 0.00005 and P = 0.02).
authors.affiliation: Shackleton Department of Anaesthesia, Southampton General Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Williams
authors.forename: A
authors.initials: A
authors.lastname: Doyle
authors.forename: D
authors.initials: D
authors.lastname: Brighouse
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal / Q000379:methods*; D000779:Anesthetics, Local; D001794:Blood Pressure / Q000187:drug effects; D002045:Bupivacaine; D004311:Double-Blind Method; D006801:Humans; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D013997:Time Factors; D001743:Urinary Bladder / Q000601:surgery*
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002045:Bupivacaine