title: Acute renal failure in falciparum malaria.
abstract: We report two patients who had cerebral malaria, heavy parasitemia, hyperbilirubinemia, hypercatabolism with rapid rises of blood urea and serum creatinine and acute renal failure. There was no evidence of intravascular hemolysis. Renal biopsy was consistent with acute tubular necrosis. Both patients responded to treatment with intravenous quinine and dialysis.
authors.affiliation: Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
authors.forename: M
authors.initials: M
authors.lastname: Segasothy
authors.forename: M
authors.initials: M
authors.lastname: Swaminathan
authors.forename: N C
authors.initials: NC
authors.lastname: Kong
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D006801:Humans; D007668:Kidney / Q000473:pathology; D007683:Kidney Tubular Necrosis, Acute / Q000209:etiology / Q000473:pathology; D016778:Malaria, Falciparum / Q000150:complications* / Q000469:parasitology / Q000628:therapy; D008297:Male; D018512:Parasitemia / Q000209:etiology; D010530:Peritoneal Dialysis; D011803:Quinine / Q000627:therapeutic use; D006435:Renal Dialysis
chemical_list: D011803:Quinine