title: Predictors of future antihypertensive use in patients with mildly elevated blood pressure.
abstract: We prospectively identified predictors of future antihypertensive use in untreated persons age 18-65 years who had elevated diastolic blood pressures of 90-104 mm Hg or systolic blood pressures of at least 140 mm Hg. Data were derived from two independent cohorts completing household surveys conducted in 1981-1984 and 8 years later, as part of the Pawtucket Heart Health Program. Demographics, self-reported health behaviors and beliefs, and physiologic measurements were obtained. Drug use was determined through structured interviews. Analysis of covariance and logistic regression were performed. In the 492 subjects, independent baseline predictors of future antihypertensive use (p < 0.05) included female gender, older age, diastolic blood pressure elevation, self-perceived high blood pressure, and self-reported salt limitation. Antihypertensive use for previously untreated mild hypertension is diverse. Older women with diastolic elevations who are health conscious are most likely to be treated.
authors.affiliation: Department of Pharmacy Practice, College of Pharmacy, University of Rhode Island, Kingston 02881, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Barbour
authors.forename: A L
authors.initials: AL
authors.lastname: Hume
authors.forename: K L
authors.initials: KL
authors.lastname: Lapane
authors.forename: C A
authors.initials: CA
authors.lastname: Derby
authors.forename: R A
authors.initials: RA
authors.lastname: Carleton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D015331:Cohort Studies; D003120:Colorado; D004363:Drug Utilization / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents