[How to combine antihypertensive drugs?].
Many hypertensive patients do not respond adequately to single-drug therapy and may therefore require two or more drugs to reach the treatment goal. The drugs used in combination therapy should have additive or synergistic effects on blood pressure. A potential benefit of combinations is to use lower doses of each drug, which may attenuate or abolish the occurrence of side effects. Different combinations are discussed, as well as the inhibition of compensatory mechanisms that may otherwise counteract the antihypertensive effect.
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Nyremedisinsk avdeling, Ullevål sykehus, Oslo.
Eide
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Kjeldsen
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Westheim
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Stokke
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HP
D000959:Antihypertensive Agents / Q000008:administration & dosage*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans
D000959:Antihypertensive Agents
Hvordan kombinere blodtrykkssenkende medikamenter?