Study of interleukin-2 receptor in schistosomiasis mansoni and its analogous changes in collagen diseases and schistosomal arthropathy.
An enzyme linked immunosorbent assay was used to quantify soluble interleukin-2 receptor (sIL-2R) in the serum of patients with different stages of S. mansoni infection, rheumatoid arthritis, systemic lupus erythematosus (SLE) and schistosomal arthropathy. The results demonstrated significant higher level of sIL-2R in different patient groups compared to the control group. The highest level of sIL-2R was recorded in hepatosplenic schistosomiasis complicated with ascites. The difference was statistically significant compared to other groups. There was no significant difference in sIL-2R regarding rheumatoid arthritis and SLE. Schistosomal arthropathy group showed significant higher level of sIL-2R compared to rheumatoid arthritis, SLE and early S. mansoni infection while the difference was insignificant compared to hepatosplenic schistosomiasis without ascites.
Khalil
H M
HM
Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
el Missiry
A G
AG
Fahmy
H M
HM
Khalil
N M
NM
Nadia
Sabry
M
M
Abdel Atty
H E
HE
Tamara
F A
FA
Amer
N
N
el Baz
H G
HG
D001170:Arthritis, Infectious / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D003095:Collagen Diseases / Q000097:blood / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D012555:Schistosomiasis mansoni / Q000097:blood / Q000276:immunology* / Q000503:physiopathology
D015415:Biomarkers; D015375:Receptors, Interleukin-2