A case of severe ovarian hyperstimulation in a healthy oocyte donor.
OBJECTIVE
To report an unexpected case of severe ovarian hyperstimulation syndrome (OHSS) and to compare E2 levels and number of follicles to other oocyte donors.


METHODS
Private assisted reproduction technology center.


METHODS
Healthy oocyte donors with normal menstrual cyclicity.


METHODS
Prophylactic and therapeutic use of human serum albumin infusions.


METHODS
The clinical development of signs and symptoms of severe OHSS.


RESULTS
More than 60% of other oocyte donors had higher E2 levels and 12% had higher number of follicles without associated OHSS.


CONCLUSIONS
The risk of developing severe OHSS cannot be predicted accurately to be low even in the absence of "risk factors."
Halme
J
J
North Carolina Center for Reproductive Medicine, Cary 27511, USA.
Toma
S K
SK
Talbert
L M
LM
D000328:Adult; D005260:Female; D005544:Forecasting; D006801:Humans; D008596:Menotropins / Q000009:adverse effects / Q000627:therapeutic use; D018587:Oocyte Donation / Q000009:adverse effects*; D016471:Ovarian Hyperstimulation Syndrome / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D012709:Serum Albumin / Q000627:therapeutic use
D012709:Serum Albumin; D008596:Menotropins