title: Three short tandem repeat loci in Japanese population.
abstract: Allele frequencies of three short tandem repeat loci, vWF, TH and GCG, were examined for 210 unrelated Japanese individuals. Eight alleles were identified with PCR and gel electrophoresis for vWF, 7 for TH and 13 for GCG, indicating that these loci are highly polymorphic. Combined discrimination power of the 3 STRs was 0.995. These results imply that the loci are useful as probes for the identification of Japanese individuals. Thus, we applied the probes to the identification of a forensic specimen that was decomposed severely. The vWF and TH probes successfully gave clear bands in gel electrophoresis, but GCG failed to be typed because of a lot of shadow bands. The results suggests the usefulness of at least the former two probes in forensic studies.
authors.affiliation: Department of Legal Medicine, Niigata University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Fujita
authors.forename: E
authors.initials: E
authors.lastname: Naito
authors.forename: K
authors.initials: K
authors.lastname: Dewa
authors.forename: H
authors.initials: H
authors.lastname: Yamanouchi
mesh_terms: D000483:Alleles; D044466:Asian People; D005554:Forensic Medicine; D005787:Gene Frequency; D005934:Glucagon / Q000235:genetics; D006801:Humans; D007564:Japan; D016133:Polymerase Chain Reaction; D012091:Repetitive Sequences, Nucleic Acid; D014446:Tyrosine 3-Monooxygenase / Q000235:genetics; D014841:von Willebrand Factor / Q000235:genetics
chemical_list: D014841:von Willebrand Factor; D005934:Glucagon; D014446:Tyrosine 3-Monooxygenase