title: Unexpected brainstem compression following routine surgery in a child with oto-palato-digital syndrome.
abstract: Oto-palato-digital syndrome type 1 is a rare condition with several features of concern to the anaesthetist. We report a patient who developed respiratory depression 5 h after general anaesthesia. This was subsequently found to be due to brainstem compression secondary to congenital deformities of the skull base and cervical vertebrae.
authors.affiliation: Department of Paediatric Intensive Care, Hospital for Sick Children, London.
authors.forename: J R
authors.initials: JR
authors.lastname: Clark
authors.forename: L J
authors.initials: LJ
authors.lastname: Smith
authors.forename: B E
authors.initials: BE
authors.lastname: Kendall
authors.forename: R C
authors.initials: RC
authors.lastname: Tasker
authors.forename: K A
authors.initials: KA
authors.lastname: Wilkinson
mesh_terms: D000293:Adolescent; D000768:Anesthesia, General; D001933:Brain Stem; D002574:Cervical Vertebrae / Q000002:abnormalities*; D002972:Cleft Palate / Q000601:surgery; D003251:Constriction, Pathologic / Q000150:complications; D006801:Humans; D008297:Male; D009958:Orofaciodigital Syndromes / Q000601:surgery*; D011183:Postoperative Complications; D012131:Respiratory Insufficiency / Q000209:etiology*; D012886:Skull / Q000002:abnormalities*; D013577:Syndrome