title: Anaesthesia and cystic fibrosis.
abstract: Cystic fibrosis occurs in 1 in 2000 children and the majority now reach adulthood. The disease is a complex multisystem disorder which is likely to challenge anaesthetists with increasing frequency. In this review the presentation and genetics of the disease are briefly described, followed by a detailed account of the pathophysiology relevant to anaesthesia. The pre-operative assessment and conduct of anaesthesia are discussed and some suggestions made regarding management.
authors.affiliation: Department of Anaesthetics, Royal Hospital for Sick Children, Edinburgh.
authors.forename: T S
authors.initials: TS
authors.lastname: Walsh
authors.forename: C H
authors.initials: CH
authors.lastname: Young
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000379:methods*; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000235:genetics / Q000503:physiopathology; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D008297:Male; D011229:Preanesthetic Medication; D011300:Preoperative Care; D012137:Respiratory System / Q000503:physiopathology