title: Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates).
abstract: BUA compiled the available data on toxicity and ecotoxicity for several acrylic and methacrylic acid esters and their corresponding acids. A comparison of these data revealed a qualitative similarity in the toxicological and ecotoxicological properties of the compounds considered. The data indicate that methacrylates are less reactive than the corresponding acrylates.
authors.affiliation: GSF Institut für Toxikologie, Oberschleissheim, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Greim
authors.forename: J
authors.initials: J
authors.lastname: Ahlers
authors.forename: R
authors.initials: R
authors.lastname: Bias
authors.forename: B
authors.initials: B
authors.lastname: Broecker
authors.forename: H
authors.initials: H
authors.lastname: Hollander
authors.forename: H P
authors.initials: HP
authors.lastname: Gelbke
authors.forename: S
authors.initials: S
authors.lastname: Jacobi
authors.forename: H J
authors.initials: HJ
authors.lastname: Klimisch
authors.forename: I
authors.initials: I
authors.lastname: Mangelsdorf
authors.forename: W
authors.initials: W
authors.lastname: Mayr
mesh_terms: D000179:Acrylates / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D001419:Bacteria / Q000187:drug effects; D001673:Biodegradation, Environmental; D002273:Carcinogens / Q000633:toxicity; D003621:Daphnia / Q000187:drug effects; D056890:Eukaryota / Q000187:drug effects; D005399:Fishes; D006801:Humans; D007928:Lethal Dose 50; D008689:Methacrylates / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D051381:Rats; D012867:Skin / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000179:Acrylates; D002273:Carcinogens; D008689:Methacrylates; C008384:methacrylic acid; C036658:acrylic acid