Antimicrobial prophylaxis for ophthalmic surgery.
Preoperative, intraoperative, and postoperative antibiotic agents have been used by ophthalmic surgeons routinely as prophylaxis for postoperative endophthalmitis. The rationale for such prophylaxis and the evidence which supports its efficacy are well founded. The optimal choice of antibiotic agent--from the standpoint of efficacy, route of delivery, adverse reactions, and cost--is far less established. This review considers these issues, as well as the role of topical disinfectants, including povidone-iodine, in preoperative prophylaxis.
Starr
M B
MB
Lally
J M
JM
D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D004202:Disinfectants / Q000627:therapeutic use; D004333:Drug Administration Routes; D009877:Endophthalmitis / Q000517:prevention & control*; D006801:Humans; D013508:Ophthalmologic Surgical Procedures; D011292:Premedication
D000900:Anti-Bacterial Agents; D004202:Disinfectants