title: Polyfunctional indole-3-carbinol derivatives: 1-(indol-3-yl)glycerols and related compounds, beta-hydroxytryptamines and ascorbigens. Chemistry and biological properties.
abstract: Earlier interaction of indole-3-carbinols with L-ascorbic acid and chemical and biological properties of formed 2-skatylderivatives of L-ascorbic acid (ascorbigens) were discussed. In this presentation the properties and stereochemistry of products of interaction of polyfunctional biologically important indole-3-carbinols (indoleglycerol analogs and beta-hydroxytryptamine derivatives) with L-ascorbic acid are investigated. Biological significance of this reaction is discussed.
authors.affiliation: Institute of New Antibiotics of the Russian Academy of Medical Sciences Moscow.
authors.forename: M N
authors.initials: MN
authors.lastname: Preobrazhenskaya
authors.forename: A M
authors.initials: AM
authors.lastname: Korolev
authors.forename: N N
authors.initials: NN
authors.lastname: Isaeva
authors.forename: E I
authors.initials: EI
authors.lastname: Lazhko
authors.forename: L A
authors.initials: LA
authors.lastname: Lomidze
mesh_terms: D000818:Animals; D016588:Anticarcinogenic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001205:Ascorbic Acid / Q000737:chemistry; D005990:Glycerol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D016588:Anticarcinogenic Agents; D007211:Indoles; D005990:Glycerol; D001205:Ascorbic Acid