title: LRRning the RIte of springs.
abstract: The determination of the crystal structure of the ribonuclease inhibitor-ribonuclease A complex provides exciting new insight on how the leucine-rich repeat allows a single molecule to get around the problem of inhibiting an entire family of enzymes.
authors.forename: R
authors.initials: R
authors.lastname: Shapiro
authors.forename: J F
authors.initials: JF
authors.lastname: Riordan
authors.forename: B L
authors.initials: BL
authors.lastname: Vallee
mesh_terms: D000818:Animals; D003461:Crystallography; D006801:Humans; D007930:Leucine / Q000737:chemistry*; D011487:Protein Conformation; D012091:Repetitive Sequences, Nucleic Acid; D012259:Ribonuclease, Pancreatic / Q000378:metabolism*; D012260:Ribonucleases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D013552:Swine
chemical_list: D012260:Ribonucleases; D012259:Ribonuclease, Pancreatic; D007930:Leucine