title: Decentration associated with asymmetric capsular shrinkage and intraocular lens design in a rabbit model.
abstract: We evaluated intraocular lens (IOL) decentration resulting from asymmetric capsular shrinkage. In 19 eyes of 10 white rabbits, a D-shaped incision was made in the anterior capsule and one of three IOL types implanted in the capsular bag: three-piece with polypropylene haptics, one-piece all-poly-(methyl methacrylate) (PMMA), or compressible disk. Eight weeks later, eyes were enucleated for assessment of IOL decentration. Mean decentration was 0.75 mm for three-piece IOLs, 0.46 mm for one-piece IOLs, and 0.30 mm for compressible-disk lenses. Decentration was significantly less in eyes with compressible-disk lenses than in those with three-piece IOLs. Although decentration was less with the compressible-disk lens, the lens is not commonly used because of the large incision and special insertion technique required. If an open-loop IOL is to be used in eyes at risk for asymmetric capsular shrinkage, our results indicate that an all-PMMA one-piece IOL would be preferable to a three-piece lens with a polypropylene haptic.
authors.affiliation: Department of Ophthalmology, Wakayama Medical College, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ohmi
authors.forename: K
authors.initials: K
authors.lastname: Uenoyama
mesh_terms: D000818:Animals; D002387:Cataract Extraction; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D007910:Lenses, Intraocular / Q000009:adverse effects*; D020366:Methylmethacrylate; D008768:Methylmethacrylates; D011126:Polypropylenes; D011183:Postoperative Complications; D011474:Prosthesis Design / Q000009:adverse effects*; D011817:Rabbits
chemical_list: D008768:Methylmethacrylates; D011126:Polypropylenes; D020366:Methylmethacrylate