[Significance of histologic bone marrow evaluation in chronic granulocytic leukemia diagnosis. III. Myeloblasts and promyelocytes].
The aim of the study was to assessment of the relationship between the number of myeloblasts in trephine biopsy in patients with chronic granulocytic leukaemia and Sokal's index. We have not found any correlation between these values. Further analysis revealed however that Sokal's index < 0.8 still qualified patients with evident signs of disease progress (increased number of layers of myeloblasts and promyelocytes in peri-trabecular and perivascular regions) to low risk group. We therefore conclude that bone marrow histology examination in chronic granulocytic leukaemia may bring valuable information concerning the real state of the disease.
Komarnicki
M
M
Klinika Hematologii Instytutu Chorób Wewnetrznych Akademii Medycznej im. K. Marcinkowskiego w Poznaniu.
Rasińska
M
M
Woźny
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006098:Granulocytes / Q000473:pathology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood / Q000473:pathology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged
Znaczenie oceny histologicznej szpiku w diagnostyce przewlekłej białaczki szpikowej. III Mieloblasty i promielocyty.