Topical treatment of Sjögren-Larsson syndrome with calcipotriol.
Two patients with Sjögren-Larsson syndrome were treated with calcipotriol in ointment and the ointment base only for 12 weeks, using a double-blind bilaterally paired comparative study. Unilateral improvement was observed in both patients in favour of the calcipotriol-treated side. The present case is the first demonstration of a substantial clinical effect of calcipotriol in the Sjögren-Larsson syndrome.
Lucker
G P
GP
Department of Dermatology, University Hospital, Nijmegen, The Netherlands.
van de Kerkhof
P C
PC
Cruysberg
J R
JR
der Kinderen
D J
DJ
Steijlen
P M
PM
D000328:Adult; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009824:Ointments; D016111:Sjogren-Larsson Syndrome / Q000188:drug therapy*
D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol