title: Unilateral acoustic tumors: how often do they recur after translabyrinthine removal?
abstract: Unilateral acoustic tumors rarely recur after total translabyrinthine removal. Review of the patient records of the House Ear Clinic revealed five recurrent tumors, for an approximate incidence of 0.3%. A questionnaire was mailed to 857 patients who were at least 9 years postoperative and failed to find any additional recurrent tumors. No preoperative or intraoperative factors were identified to predict recurrence. The average time interval from initial removal to recurrence was approximately 10 years. Flow cytometric analysis did not reveal any fundamental differences between the recurrent acoustic tumor group and a larger group of 112 acoustic tumors. Based on observed growth rates of the recurrent acoustic tumors, a single gadolinium-enhanced magnetic resonance image 5 years after surgery is advised. To prevent recurrence, a margin of normal-appearing proximal eighth cranial nerve should be removed and the nerve stump cauterized.
authors.affiliation: House Ear Clinic, Los Angeles, USA.
authors.forename: C
authors.initials: C
authors.lastname: Shelton
mesh_terms: D000328:Adult; D002455:Cell Division / Q000235:genetics; D004273:DNA, Neoplasm; D004171:Diploidy; D007758:Ear, Inner; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009464:Neuroma, Acoustic / Q000473:pathology* / Q000601:surgery*; D010036:Otolaryngology / Q000379:methods; D012189:Retrospective Studies; D016196:S Phase
chemical_list: D004273:DNA, Neoplasm