title: Choriocarcinoma of the bladder. Report of a case of primary tumor or late metastasis of a molar pregnancy.
abstract: Choriocarcinoma of the bladder was diagnosed in a 54-year-old woman presenting with macroscopic hematuria 17 years following evacuation of a molar pregnancy. The patient was treated by cystoscopic transurethral tumor resection followed by three courses of triple-agent chemotherapy and total abdominal hysterectomy with bilateral salpingo-oophorectomy. Six months later a gradual rise in beta-human chorionic gonadotropin levels led to the diagnosis of recurrent bladder tumor at the site of the previous tumor. The patient underwent a conservative partial cystectomy, and 12 months postoperatively there was no evidence of disease. It is unclear whether the patient developed a primary urinary bladder choriocarcinoma or late metastatic disease from the previous molar pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Carmel Medical Center, Haifa, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Yishai
authors.forename: J
authors.initials: J
authors.lastname: Atad
authors.forename: J
authors.initials: J
authors.lastname: Bornstein
authors.forename: Y
authors.initials: Y
authors.lastname: Sova
authors.forename: Y
authors.initials: Y
authors.lastname: Mecz
authors.forename: A
authors.initials: A
authors.lastname: Lurie
authors.forename: M
authors.initials: M
authors.lastname: Lurie
authors.forename: H
authors.initials: H
authors.lastname: Abramovici
mesh_terms: D002822:Choriocarcinoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000628:therapy; D011247:Pregnancy; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D014594:Uterine Neoplasms / Q000473:pathology*