title: [Acute bacterial meningitis and foramen magnum syndrome as a presentation of odontoid osteomyelitis. A case report].
abstract: A 77-year-old male was hospitalized with a 6-day history of severe posterior cervical pain and headache. An initial lumbar puncture revealed polymorphonuclear pleocytosis indicating pyogenic meningitis. The blood and throat cultures on admission were positive for Staphylococcus aureus. A combination of ceftriaxone and ABPC, both of which were sensitive to the pathogen, were intravenously administered for one month, by which he responded well as to the meningitis. However, he was found to have persistent neck pain, and wasting and weakness of the shoulder girdles, which were associated with polyneuropathy-like sensory loss. Neuroimaging studies disclosed a partial destruction of the odontoid process, subluxation of the atlantoaxial joint, MRI evidence of an inflammatory pseudomass formation dorsal to the odontoid process and an increased uptake of radionuclide on bone scanning, all of which were indicative of osteomyelitic processes at the region of the axis; i.e., the meningitis was thought to be secondary to osteomyelitis of the odontoid process and hence the foramen magnum syndrome characteristic to this particular case was explained by the compression of the cervicomedullary junction due to the pseudomass. To our knowledge, this is the first case of primary odontoid osteomyelitis to be reported in Japan.
authors.affiliation: Department of Neurology, Fukushima Medical College.
authors.forename: J
authors.initials: J
authors.lastname: Akanuma
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiura
authors.forename: T
authors.initials: T
authors.lastname: Tsukamoto
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
mesh_terms: D000208:Acute Disease; D000368:Aged; D005539:Foramen Magnum; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000209:etiology*; D009809:Odontoid Process; D010019:Osteomyelitis / Q000150:complications*; D011115:Polyneuropathies / Q000209:etiology*; D012678:Sensation Disorders / Q000209:etiology; D013577:Syndrome