title: [Changes in the intramural nervous system in idiopathic megacolon in adults].
abstract: The ganglions of the muscular-interic plexus were studied in 94 surgical adult patients with an "idiopathic" megacolon. Both congenital and acquired ganglion lesions were found. Hypogangliosis (58% of patients), hypergangliosis (12% of patients) and hypoplasia (3.5% of patients) are considered as congenital lesions. Acquired degenerative changes of the nervous cells in the ganglions of the intramural nervous system were observed in 26% of patients of this group. Ultrastructurally, some of the ganglioneurocyte lesions were of the reactive type, while the others of the destructive type.
authors.forename: T I
authors.initials: TI
authors.lastname: Basilova
authors.forename: G I
authors.initials: GI
authors.lastname: Vorob'ev
authors.forename: T A
authors.initials: TA
authors.lastname: Nasyrina
mesh_terms: D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000473:pathology; D005725:Ganglia, Autonomic / Q000473:pathology; D006801:Humans; D007420:Intestine, Large / Q000294:innervation*; D008531:Megacolon / Q000209:etiology / Q000473:pathology*
vernacular_title: Izmeneniia intramural'noĭ nervnoĭ sistemy pri idiopaticheskom megakolon u vzroslykh.