Clinical review 73: Medical treatment of androgen-dependent hirsutism.
Although hirsutism is more a cosmetic and psychosocial problem than a disease, hirsute women are often some of the most grateful patients in an endocrinologist's practice. The combination of mechanical hair removal and judicious use of medications will improve hair growth in most women. Unfortunately, no drug is approved by regulatory agencies in North America for treatment of hirsutism. Well designed comparative studies with objective end points are needed to demonstrate which drugs work best in which hirsute women. Because pharmaceutical companies are reluctant to market drugs for women of child-bearing age, there has been little industry support for such studies.
Rittmaster
R S
RS
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
D000311:Adrenal Glands / Q000378:metabolism; D000726:Androgen Antagonists / Q000627:therapeutic use*; D000728:Androgens / Q000502:physiology*; D003276:Contraceptives, Oral / Q000627:therapeutic use; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives; D006628:Hirsutism / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D010053:Ovary / Q000378:metabolism
D000726:Androgen Antagonists; D000728:Androgens; D003276:Contraceptives, Oral; D007987:Gonadotropin-Releasing Hormone