title: Total antioxidant capacity of seminal plasma is different in fertile and infertile men.
abstract: OBJECTIVE
  To determine if the total antioxidant capacity of seminal plasma is different in fertile and infertile men.
  
  
  METHODS
  An enhanced chemiluminescence assay applied to seminal plasma from groups of fertile and infertile men.
  
  
  METHODS
  The Assisted Conception Unit, Royal Maternity Hospital, Belfast.
  
  
  METHODS
  Men of proven fertility whose partners had an ongoing pregnancy resulting from IVF and male partners of couples attending our subfertility clinic.
  
  
  RESULTS
  Total antioxidant capacity was significantly higher in seminal plasma from fertile men than from that of infertile men with normozoospermic samples that exhibited reactive oxygen species or asthenozoospermic samples with or without reactive oxygen species activity.
  
  
  CONCLUSIONS
  Seminal plasma from infertile men has lower antioxidant levels than that of fertile men, particularly of patients whose semen have poor sperm motility. The presence of reactive oxygen species activity in sperm of infertile groups also is associated with lower levels of chain-breaking antioxidants in seminal plasma.
authors.affiliation: Department of Obstetrics and Gynaecology, Queen's University of Belfast, United Kingdom.
authors.forename: S E
authors.initials: SE
authors.lastname: Lewis
authors.forename: P M
authors.initials: PM
authors.lastname: Boyle
authors.forename: K A
authors.initials: KA
authors.lastname: McKinney
authors.forename: I S
authors.initials: IS
authors.lastname: Young
authors.forename: W
authors.initials: W
authors.lastname: Thompson
mesh_terms: D005298:Fertility / Q000502:physiology*; D006801:Humans; D007248:Infertility, Male / Q000503:physiopathology*; D008163:Luminescent Measurements; D008297:Male; D010100:Oxygen / Q000037:antagonists & inhibitors*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D012661:Semen / Q000502:physiology*
chemical_list: D017382:Reactive Oxygen Species; D010100:Oxygen