Osteoporosis. Clinical features, prevention, and treatment.
Osteoporosis is a significant and growing problem among the elderly. Although therapies exist to treat established disease, preventive measures that maintain bone mass throughout life are preferable. Osteoporosis is a condition resulting in an increased risk of skeletal fractures owing to a reduction in the volume of bone tissue. There is a preservation of the normal ratio of unmineralized-to-mineralized bone matrix. This disease affects postmenopausal women most frequently, and a link clearly exists between estrogen deficiency and accelerated bone loss. Diet, exercise, and other forms of treatment exist for well-established disease.
Gambert
S R
SR
Department of Medicine, New York Medical College, Valhalla, USA.
Schultz
B M
BM
Hamdy
R C
RC
D000368:Aged; D000375:Aging; D015519:Bone Density; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy