title: The results of denatured homologous vein grafts as conduits for secondary haemodialysis access surgery.
abstract: OBJECTIVE
  To determine the value of denatured homologous vein grafts as a conduit for secondary haemodialysis access.
  
  
  METHODS
  Retrospective clinical study.
  
  
  METHODS
  2 University Hospitals.
  
  
  METHODS
  One-hundred-and-twenty-five patients received 195 grafts over a period of five years. Fifty-six first grafts (45%) functioned without complications throughout the study period of 5.8 years.
  
  
  RESULTS
  Primary patency was 57% after 1 year and 25% after 3 years of follow-up. Of the initial grafts, 69 (55%) needed 161 interventions, for thrombosis (n = 59), stenosis (n = 43), failure beyond repair (n = 40), aneurysm (n = 12), infection (n = 4), steal syndrome (n = 1), and other causes (n = 2). Secondary patency was 76% at 1 year and 52% at 3 years of follow-up. A major advantage of these grafts was the low rate (2.6%) of infection. Aneurysm formation occurred 17 times in 195 grafts (8.7%).
  
  
  CONCLUSIONS
  Denatured homologous vein graft is a good alternative in secondary access surgery.
authors.affiliation: Department of Surgery, University Hospital Utrecht, The Netherlands.
authors.forename: R J
authors.initials: RJ
authors.lastname: Heintjes
authors.forename: B C
authors.initials: BC
authors.lastname: Eikelboom
authors.forename: J J
authors.initials: JJ
authors.lastname: Steijling
authors.forename: R W
authors.initials: RW
authors.lastname: van Reedt Dortland
authors.forename: F H
authors.initials: FH
authors.lastname: van der Heijden
authors.forename: M
authors.initials: M
authors.lastname: Bastini
authors.forename: Y
authors.initials: Y
authors.lastname: van der Graaf
authors.forename: P J
authors.initials: PJ
authors.lastname: Blankestijn
authors.forename: J
authors.initials: J
authors.lastname: Vos
mesh_terms: D001166:Arteriovenous Shunt, Surgical / Q000379:methods*; D001807:Blood Vessel Prosthesis; D001916:Brachial Artery / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005542:Forearm / Q000098:blood supply; D006083:Graft Occlusion, Vascular / Q000453:epidemiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D006435:Renal Dialysis; D012189:Retrospective Studies; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation*; D013997:Time Factors; D014021:Tissue Preservation; D014654:Vascular Patency / Q000502:physiology