PKC-dependent activation of the type II adenylate cyclase in airway smooth muscle limits the bradykinin-stimulated ERK-2 pathway.
Pyne
N J
NJ
Department of Physiology and Pharmacology, University of Strathclyde, Glasgow, Scotland, U.K.
Stevens
P
P
Moughal
N
N
Pyne
S
S
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D001920:Bradykinin / Q000494:pharmacology*; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000378:metabolism*; D002478:Cells, Cultured; D003839:Deoxyadenosines / Q000494:pharmacology; D004789:Enzyme Activation; D006165:Guanylyl Imidodiphosphate / Q000494:pharmacology; D006168:Guinea Pigs; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D019950:Mitogen-Activated Protein Kinase 1; D009130:Muscle, Smooth / Q000187:drug effects / Q000201:enzymology*; D011493:Protein Kinase C / Q000378:metabolism*; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D012137:Respiratory System / Q000187:drug effects / Q000201:enzymology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
D003839:Deoxyadenosines; D007527:Isoenzymes; D006165:Guanylyl Imidodiphosphate; D011505:Protein-Tyrosine Kinases; D011493:Protein Kinase C; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D019950:Mitogen-Activated Protein Kinase 1; D000262:Adenylyl Cyclases; D013755:Tetradecanoylphorbol Acetate; D001920:Bradykinin