[Blood sialic acids in atherosclerosis].
Determination of the total (protein- and lipid-bound) sialic acid in blood sera of atherosclerotic patients (registered thickening of coronary vessels) and donors revealed that the concentration of the both types of sialic acids in the blood sera of atherosclerotic patients are increased. The concentration of total sialic acid in patients' sera was, on the average, by 20% higher than that in donors' sera. The identity of protein content in patients' and donors' sera suggests that under atherosclerosis serum proteins are sialated in a greater degree as compared to norm. The concentration of lipid-bound sialic acid in patients' sera is higher than that in donors' sera. However, calculated per blood cholesterol, the concentration of lipid-bound sialic acid is practically identical in both patient and donors, thus indicating that increased sialoglycolipid content in patients' sera correlates with increased lipoprotein content in these sera in comparison with norm.
Gracheva
E V
EV
Golovanova
N K
NK
Kononova
O I
OI
Kozlov
S G
SG
Prokazova
N V
NV
Liakishev
A A
AA
D000328:Adult; D001161:Arteriosclerosis / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008875:Middle Aged; D012794:Sialic Acids / Q000097:blood*
D008055:Lipids; D008074:Lipoproteins; D012794:Sialic Acids; D002784:Cholesterol
Sialovye kisloty syvorotki krovi pri ateroskleroze.