title: Does compression of the base of the penis improve the efficacy of intracavernosal injection of prostaglandin E1 for impotence? A randomized controlled study.
abstract: The objective of this study was to evaluate the effect on erections of impeding venous blood flow following intracavernosal injections of prostaglandin E1. Dispersion of injected X-ray contrast medium indicated that application of the RMRI penile clamp to the base of the penis retarded venous outflow. The clamp was then tested in impotent men to determine whether their erectile response was enhanced. Erectile response was assessed using a Rigiscan monitor, palpation of the penis by a staff nurse and the patient's subjective impression. The results demonstrate that there is no significant improvement in erectile response following venous compression.
authors.affiliation: Reproductive Medicine Research Institute, QE II Medical Centre, Nedlands, Western Australia.
authors.forename: J C
authors.initials: JC
authors.lastname: el-Saleh
authors.forename: E J
authors.initials: EJ
authors.lastname: Keogh
authors.forename: K K
authors.initials: KK
authors.lastname: Chew
authors.forename: C M
authors.initials: CM
authors.lastname: Earle
authors.forename: J L
authors.initials: JL
authors.lastname: Lee
authors.forename: J W
authors.initials: JW
authors.lastname: Wearmouth
mesh_terms: D000328:Adult; D000368:Aged; D000527:Alprostadil / Q000008:administration & dosage* / Q000627:therapeutic use*; D003287:Contrast Media; D004311:Double-Blind Method; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D007472:Iohexol; D008297:Male; D008875:Middle Aged; D010410:Penile Erection / Q000187:drug effects; D010413:Penis / Q000000981:diagnostic imaging / Q000502:physiology*; D011312:Pressure; D011859:Radiography
chemical_list: D003287:Contrast Media; D007472:Iohexol; D000527:Alprostadil