[A retrospective clinico-morphologic study of insulinoma].
Surgical material from 51 patients operated on for insulinoma is studied. Three histological variants of insulinoma are distinguished: adenoma-like, insular-ductal and carcinoid-like. The structure of Langerhans islands outside the tumour is described and the diagnostic criteria of insuloma-microadenoma are presented. Multiple nests of the endocrine cells are regarded either as a manifestation of the multifocal island pathology or as a marker of non-diagnosed insuloma. There is a need of distinguishing between the terms related to the nosology and histogenesis of endocrine pancreatic tumours.
Kazantseva
I A
IA
Kalinin
A P
AP
Poliakova
G A
GA
Davydova
I V
IV
Tikhomirov
O Iu
OIu
D000236:Adenoma / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007003:Hypoglycemia / Q000473:pathology*; D007340:Insulinoma / Q000145:classification / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000145:classification / Q000473:pathology*; D012189:Retrospective Studies; D013577:Syndrome
Retrospektivnoe kliniko-morfologicheskoe issledovanie insulinom.