title: Distribution of arginine-vasopressin and vasoactive intestinal peptide messenger RNA in the suprachiasmatic nucleus of the sheep.
abstract: The distribution of mRNAs for vasoactive intestinal peptide (VIP) and arginine-vasopressin (VP) was studied in the hypothalamus of the sheep by in situ hybridization. VIP mRNA was detected in the supraoptic nucleus (SON) and in the median part of the suprachiasmatic nucleus (SCN). VP mRNA was observed in the magnocellular system of the hypothalamus and in the dorso-lateral part of the SCN. These results confirm that the SCN is a site of synthesis of both peptides. Therefore, VIP and VP may be involved in diverse physiological functions including the functioning of the biological clock constituted by the SCN.
authors.affiliation: Laboratoire de Neuroendocrinologie, Université de Tours, Faculté des Sciences, France.
authors.forename: A
authors.initials: A
authors.lastname: Tessonneaud
authors.forename: C
authors.initials: C
authors.lastname: Bonnefond
authors.forename: R
authors.initials: R
authors.lastname: Monnerie
authors.forename: M C
authors.initials: MC
authors.lastname: Viguier-Martinez
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000096:biosynthesis*; D005260:Female; D007091:Image Processing, Computer-Assisted; D017403:In Situ Hybridization; D012333:RNA, Messenger / Q000378:metabolism*; D012756:Sheep; D013493:Suprachiasmatic Nucleus / Q000187:drug effects / Q000378:metabolism*; D013495:Supraoptic Nucleus / Q000378:metabolism; D014660:Vasoactive Intestinal Peptide / Q000096:biosynthesis*
chemical_list: D012333:RNA, Messenger; D001127:Arginine Vasopressin; D014660:Vasoactive Intestinal Peptide