title: Adenosine deaminase (ADA) deficiency as the unexpected cause of CD4+ T-lymphocytopenia in two HIV-negative adult female siblings.
authors.affiliation: Purine Research Laboratory, UMDS Guy's Hospital, London, GB.
authors.forename: L D
authors.initials: LD
authors.lastname: Fairbanks
authors.forename: H A
authors.initials: HA
authors.lastname: Simmonds
authors.forename: A D
authors.initials: AD
authors.lastname: Webster
authors.forename: C L
authors.initials: CL
authors.lastname: Shovlin
authors.forename: J M
authors.initials: JM
authors.lastname: Hughes
mesh_terms: D000243:Adenosine Deaminase / Q000172:deficiency* / Q000235:genetics / Q000627:therapeutic use*; D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006580:Genetic Carrier Screening; D018023:HIV Seronegativity; D006720:Homozygote; D006801:Humans; D008297:Male; D010375:Pedigree; D016511:Severe Combined Immunodeficiency / Q000235:genetics / Q000276:immunology* / Q000628:therapy; D013997:Time Factors
chemical_list: D000243:Adenosine Deaminase; C051409:pegademase bovine