title: Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction.
authors.affiliation: Department of Biochemistry, Rheinisch-Westfälische Technische Hochshule Aachen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Ehlers
authors.forename: J
authors.initials: J
authors.lastname: Grötzinger
authors.forename: F D
authors.initials: FD
authors.lastname: de Hon
authors.forename: J
authors.initials: J
authors.lastname: Müllberg
authors.forename: J P
authors.initials: JP
authors.lastname: Brakenhoff
authors.forename: A
authors.initials: A
authors.lastname: Wollmer
authors.forename: S
authors.initials: S
authors.lastname: Rose-John
mesh_terms: D000818:Animals; D015703:Antigens, CD; D001665:Binding Sites; D050822:Cytokine Receptor gp130; D006801:Humans; D015850:Interleukin-6 / Q000737:chemistry* / Q000378:metabolism; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000737:chemistry / Q000378:metabolism; D051379:Mice; D018123:Receptors, Interleukin / Q000378:metabolism*; D019947:Receptors, Interleukin-6; D015398:Signal Transduction; D013329:Structure-Activity Relationship
chemical_list: D015703:Antigens, CD; C494199:IL6ST protein, human; C494200:Il6st protein, mouse; D015850:Interleukin-6; D008562:Membrane Glycoproteins; D018123:Receptors, Interleukin; D019947:Receptors, Interleukin-6; D050822:Cytokine Receptor gp130