title: A new therapeutic approach for sickle cell disease. Blockade of the red cell Ca(2+)-activated K+ channel by clotrimazole.
authors.affiliation: Department of Pathology, Children's Hospital, Boston, MA 02115, USA.
authors.forename: C
authors.initials: C
authors.lastname: Brugnara
authors.forename: L
authors.initials: L
authors.lastname: De Franceschi
authors.forename: C C
authors.initials: CC
authors.lastname: Armsby
authors.forename: N
authors.initials: N
authors.lastname: Saadane
authors.forename: M
authors.initials: M
authors.lastname: Trudel
authors.forename: Y
authors.initials: Y
authors.lastname: Beuzard
authors.forename: A
authors.initials: A
authors.lastname: Rittenhouse
authors.forename: N
authors.initials: N
authors.lastname: Rifai
authors.forename: O
authors.initials: O
authors.lastname: Platt
authors.forename: S L
authors.initials: SL
authors.lastname: Alper
mesh_terms: D000284:Administration, Oral; D000755:Anemia, Sickle Cell / Q000188:drug therapy*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003022:Clotrimazole / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D026902:Potassium Channel Blockers; D012016:Reference Values
chemical_list: D026902:Potassium Channel Blockers; D003022:Clotrimazole; D002118:Calcium