Tuberous sclerosis complex: a review with a study of eight cases.
This paper reviews the subject of tuberous sclerosis complex and presents data in eight cases of this condition, admitted to Hospital Universiti Sains Malaysia over a period of 8.5 years. The average age at presentation was 53 months. Seizures were the most common presenting feature. Male to female ratio was 3:1. Family history was present in four patients. All of the patients had one or more skin lesions. Six of them had retinal in six patients. Two patients had renal angiomyolipomas. A high index of hamartomas. Cardiac tumours were found in two patients. Multiple subependymal hamartomas were detected in six patients. Two patients had renal angiomyolipomas. A high index of suspicion and a detailed physical examination is required to diagnose this rare disorder.
Malik
A S
AS
Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan.
Hussin
Z A
ZA
Shriwas
S R
SR
Kasim
Z M
ZM
D002648:Child; D002675:Child, Preschool; D005260:Female; D006222:Hamartoma / Q000150:complications*; D006338:Heart Neoplasms / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D012164:Retinal Diseases / Q000150:complications*; D012189:Retrospective Studies; D012640:Seizures / Q000150:complications*; D012871:Skin Diseases / Q000150:complications*; D013577:Syndrome; D014402:Tuberous Sclerosis / Q000150:complications*