Risk factors for hepatitis A infection in France: drinking tap water may be of importance.
The prevalence of serologic markers for hepatitis A was investigated in 936 French male military recruits from October 1992 to June 1993. Data were collected in order to assess the evolution of seroprevalence level according to the decline observed for several years and to appreciate the importance of potential risk factors. The overall prevalence of antibody against hepatitis A virus was 16.3%. The prevalence was higher among those with high number of siblings and whose Father's occupation falls into low professional class categories. Multivariate analysis found that high level of seroprevalence was also associated with tap water consumption (odd ratio (OR) = 1.56; p < 0.04), overseas travels (OR = 2.26; p < 0.001) and was higher for recruits reporting an history of clinical jaundice (OR = 2.27; p < 0.01). Together with more anticipated factors, tap water consumption may be of importance in France and this study points out the potential part taken by chlorinated water.
Lagarde
E
E
Centre de Transfusion Sanguine des Armées, Clamart, France.
Joussemet
M
M
Lataillade
J J
JJ
Fabre
G
G
D000293:Adolescent; D000328:Adult; D004326:Drinking; D004522:Educational Status; D005192:Family Health; D005602:France / Q000453:epidemiology; D006506:Hepatitis A / Q000453:epidemiology* / Q000276:immunology; D006508:Hepatitis Antibodies / Q000097:blood; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007565:Jaundice / Q000453:epidemiology; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012923:Social Class; D014195:Travel / Q000706:statistics & numerical data; D018508:Water Purification; D014881:Water Supply
D006508:Hepatitis Antibodies; D007074:Immunoglobulin G