title: [Drug interactions and antibiotics].
abstract: Situations that require the use of systemic antibiotic therapy are common and drug interactions are potentially frequent. These interactions may be deleterious and lead to reduction of therapeutic index, enhancement of toxic risk or may be favourable, with optimization of pharmacokinetics or pharmacodynamics. The mechanisms of these interactions are discussed.
authors.affiliation: Service de Médecine Interne B, CHU, Hôpital Caremeau, Nimes, France.
authors.forename: J
authors.initials: J
authors.lastname: Jourdan
authors.forename: A
authors.initials: A
authors.lastname: Sotto
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000494:pharmacology*; D004347:Drug Interactions; D004357:Drug Synergism; D004359:Drug Therapy, Combination / Q000494:pharmacology; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Interactions médicamenteuses et antibiotiques.