An outbreak of BCG related lymphadenitis in Malaysian infants.
A study was done on 638 infants with BCG related lymphadenitis seen between August 1990 and December 1993. Most infants (86.5%) had developed symptoms by six months after vaccination and the nodes became suppurative in 317. Surgical procedures were carried out in 82 cases and the rest were managed conservatively. The mean duration to resolution was 6.6 months (range 1 to 29 months). This outbreak was related to a change from the Japan to the Pasteur strain of BCG. The incidence remained high ( > 15 per 1000 live births) despite a dose reduction from 0.1 ml to 0.05 ml, but declined when the Japan strain was reintroduced in April 1992.
Hooi
L N
LN
Chest Clinic, Penang Hospital, Jalan Residensi.
Athiyah
S O
SO
D001500:BCG Vaccine / Q000009:adverse effects*; D002675:Child, Preschool; D004196:Disease Outbreaks; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008199:Lymphadenitis / Q000453:epidemiology* / Q000209:etiology* / Q000628:therapy; D008296:Malaysia; D016896:Treatment Outcome
D001500:BCG Vaccine