[The effect of qing guang kang on the metabolism of retinal ganglionic cells in rats after artificial acute high intraocular pressure].
A modified cytochrome oxidase (CO) histochemical and computer image techniques were used to examine the effect of Qing Guang Kang (QGK) injection on the metabolism of rat retinas after artificial acute high intraocular pressure. The results show that 75% of the average arterial blood pressure as the perfusing pressure of the anterior chamber of rats can lead to the decrease of numbers of CO active retinal ganglionic cells and their grey values. QGK possess the protective and/or improving effects on the CO active retinal ganglionic cells of rat under artificial acute high intraocular pressure. In the study, the data of density and the grey value of CO active ganglionic cells in the experimental models with QGK injection are significantly different from those of the control group (P < 0.05).
Jia
L
L
Department of Ophthalmology, Second Affiliated Hospital, Hunan Medical University, Changsha.
Liu
Z
Z
Luo
X
X
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D003576:Electron Transport Complex IV / Q000378:metabolism*; D005260:Female; D007091:Image Processing, Computer-Assisted; D008297:Male; D009798:Ocular Hypertension / Q000188:drug therapy / Q000201:enzymology*; D051381:Rats; D012165:Retinal Ganglion Cells / Q000201:enzymology*; D014665:Vasodilator Agents / Q000494:pharmacology*
D004365:Drugs, Chinese Herbal; D014665:Vasodilator Agents; D003576:Electron Transport Complex IV