Hepatoid carcinoma of the stomach.
A patient with primary gastric carcinoma exhibiting hepatoid differentiation is described. The tumor itself was not associated with a high serum alpha-fetoprotein, but the cells stained positive for alpha-fetoprotein and alpha-1 antitrypsin. The patient underwent a total gastrectomy and wedge excision of the liver metastasis. The presence of metastatic hepatoid adenocarcinoma of the stomach should be considered in a patient who, during surgery for a primary gastric carcinoma, is found to have a liver metastasis that is diagnosed by frozen-section biopsy as a hepatoma. Because of lymph node and liver metastasis, prognosis appears to be poor for such patients.
deLorimier
A
A
Tripler Army Medical Center, Hawaii.
Park
F
F
Aranha
G V
GV
Reyes
C
C
D000230:Adenocarcinoma / Q000473:pathology*; D006528:Carcinoma, Hepatocellular / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins