title: Symptomatic tumors affecting the urinary tract in children with neurofibromatosis.
abstract: OBJECTIVE
  We determined the need for urological screening in children with neurofibromatosis.
  
  
  METHODS
  Of 96 children with neurofibromatosis treated at our institution 6 (6.2%) had a symptomatic tumor that affected the urinary tract.
  
  
  RESULTS
  There were 5 plexiform neurofibromas and 1 prostatic rhabdomyosarcoma. Five children had a palpable abdominal mass and 3 required urinary diversion.
  
  
  CONCLUSIONS
  Since most morbidity resulted because tumors were advanced by the time symptoms developed, we suggest that children with neurofibromatosis be screened annually with medical history, physical examination, urinalysis and serum chemistry studies for tumors that affect the urinary tract.
authors.affiliation: Scottish Rite Childrens Medical Center, Atlanta, Georgia, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Barone
authors.forename: C A
authors.initials: CA
authors.lastname: Massad
authors.forename: T S
authors.initials: TS
authors.lastname: Parrott
authors.forename: B H
authors.initials: BH
authors.lastname: Broecker
authors.forename: J R
authors.initials: JR
authors.lastname: Woodard
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009455:Neurofibroma / Q000209:etiology*; D009456:Neurofibromatosis 1 / Q000150:complications*; D011471:Prostatic Neoplasms / Q000209:etiology*; D012208:Rhabdomyosarcoma / Q000209:etiology*; D014571:Urologic Neoplasms / Q000209:etiology*