Choriocarcinoma of the bladder. Report of a case of primary tumor or late metastasis of a molar pregnancy.
Choriocarcinoma of the bladder was diagnosed in a 54-year-old woman presenting with macroscopic hematuria 17 years following evacuation of a molar pregnancy. The patient was treated by cystoscopic transurethral tumor resection followed by three courses of triple-agent chemotherapy and total abdominal hysterectomy with bilateral salpingo-oophorectomy. Six months later a gradual rise in beta-human chorionic gonadotropin levels led to the diagnosis of recurrent bladder tumor at the site of the previous tumor. The patient underwent a conservative partial cystectomy, and 12 months postoperatively there was no evidence of disease. It is unclear whether the patient developed a primary urinary bladder choriocarcinoma or late metastatic disease from the previous molar pregnancy.
Yishai
D
D
Department of Obstetrics and Gynecology, Carmel Medical Center, Haifa, Israel.
Atad
J
J
Bornstein
J
J
Sova
Y
Y
Mecz
Y
Y
Lurie
A
A
Lurie
M
M
Abramovici
H
H
D002822:Choriocarcinoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000628:therapy; D011247:Pregnancy; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D014594:Uterine Neoplasms / Q000473:pathology*