In vitro susceptibility of Mucor ramosissimus Samutsevitsch, a rare fungal pathogen, to antimycotics.
The in vitro susceptibility of a rare fungal pathogen, Mucor ramosissimus Samutsevitsch, to antimycotics in clinical use was determined. Minimal inhibitory concentrations (MICs) and minimal fungicidal concentrations (MFCs) were (MIC/MFC, microgram/ml): amphotericin B, 3.125/25; miconazole, 6.25/6.25; clotrimazole, 25/25; fluconazole, 5-fluorocytosine, itraconazole, and ketoconazole, > or = 100/100. Our results show that amphotericin B and miconazole are the most effective antimycotics.
Sharma
R
R
Department of Pediatrics, University of Florida Health Science Center, Jacksonville 32209-6511, USA.
Sekhon
A S
AS
Premachandra
B R
BR
D000935:Antifungal Agents / Q000494:pharmacology*; D005431:Florida; D006801:Humans; D008826:Microbial Sensitivity Tests; D009089:Mucor / Q000145:classification / Q000187:drug effects*; D015203:Reproducibility of Results; D013045:Species Specificity
D000935:Antifungal Agents