title: [Visual function analysis of diabetic retinopathy using a contrast sensitivity analyser and usefulness of nicardipine hydrochloride].
abstract: Contrast sensitivity was measured in patients with mild diabetic retinopathy using a contrast sensitivity analyser on a personal computer to evaluate visual function. The effect of nicardipine hydrochloride for visual function in mild diabetic retinopathy was also evaluated. Suppression of contrast sensitivity in a comprehensive band of spatial frequency was seen in the patients with normal visual acuity. Apparent improvement of contrast sensitivity was seen in the patients after 3 months of nicardipine hydrochloride treatment. It became clear that even if patients with mild diabetic retinopathy have normal visual acuity, measurement of contrast sensitivity is very important to evaluate the visual function. We also found that nicardipine hydrochloride is effective in treating the impairment of visual function in patients with mild diabetic retinopathy.
authors.affiliation: Department of Opthalmology, School of Medicine, Kitasato University, Kanagawa-ken, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Higuchi
authors.forename: T
authors.initials: T
authors.lastname: Fukuda
authors.forename: K
authors.initials: K
authors.lastname: Ukai
authors.forename: M
authors.initials: M
authors.lastname: Miyata
mesh_terms: D000328:Adult; D000368:Aged; D015350:Contrast Sensitivity / Q000187:drug effects*; D003930:Diabetic Retinopathy / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009529:Nicardipine / Q000627:therapeutic use*
chemical_list: D009529:Nicardipine