title: Mineralizing microangiopathy: CT and MRI.
abstract: Mineralizing microangiopathy, a distinctive histopathologic process involving the microvasculature of the central nervous system (CNS), is usually seen following combined radiation and chemotherapy for the treatment of CNS neoplasms in childhood. CT typically demonstrates calcification within the basal ganglia and subcortical white matter. The areas of calcification may give paradoxically increased signal on T1-weighted MRI due to a surface-relaxation mechanism, and decreased signal on T2-weighted images.
authors.affiliation: Department of Radiology, Tripler Army Medical Center, Honolulu, HI 96859, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Shanley
mesh_terms: D000293:Adolescent; D002114:Calcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed