[Pure form of primary ovarian choriocarcinoma. Report of a case].
Ovarian choriocarcinoma from the germ cells is a very rare malignant neoplasia. About the pure form, very few cases have been reported in medical literature. Ovarian choriocarcinoma may originate in three modalities. As primary choriocarcinoma associated to ovarian pregnancy, 2. As a metastatic ovarian carcinoma, from other organs, mainly the uterus, 3. As a primary tumour of germ cells with differentiation to trophoblastic structures. The latter grows in girls or in adult woman, generally young, where necessarily pregnancy has to be excluded. A case is presented of a 21 years old woman, treated at Hospital General "Dr. Miguel Silva", Morelia, Mich. single, without sexual life, with an abdomino-pelvic tumor of 24 cm, from the right ovary and adhered to ascending colon. Beta subunity of chorionic gonadotrophin was 200,000 mUI/ml of blood plasma. At laparotomy a right ovarian tumour, with infiltration to ascending colon, was found; this required total hysterectomy with bilateral salpingo-oophorectomy and right hemicolectomy. After surgery the patient received chemotherapy with cisplatin, bleomicin and vinblastine. After the third treatment cycle and at three months, chorionic gonadotropin became negative; and at four years follow up residual tumoural activity is absent. Largest mortality with these tumors appears during early post-operative stage and it is atributed to the tumour itself or to post-operative complications. If the patient survives this stage and with a good chemotherapeutic program, survival and even complete cure, occurs.
Trigueros Velázquez
M
M
Hospital General, Dr. Miguel Silva, SSA, Morelia, Mich.
Sereno Coló
J A
JA
Villagrán Urive
J
J
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D002822:Choriocarcinoma / Q000473:pathology / Q000601:surgery*; D006063:Chorionic Gonadotropin / Q000097:blood; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D010052:Ovariectomy; D011182:Postoperative Care
D006063:Chorionic Gonadotropin
Coriocarcinoma puro, primario, del ovario. Presentación de un caso.