Glutathione S-transferases: alpha-naphthyl acetate activity and possible role in insecticide resistance.
Rat liver and house fly, Musca domestica L., glutathione S-transferases were purified by affinity chromatography and chromatofocusing. The specific activity with alpha-naphthyl acetate (a substrate, for general esterase activity) was determined. Some of the esterase activity that is normally assayed for resistance is apparently caused by the activity of the glutathione S-transferase.
Lalah
J O
JO
Department of Toxicology, North Carolina State University, Raleigh 27695, USA.
Chien
C I
CI
Motoyama
N
N
Dauterman
W C
WC
D000818:Animals; D005982:Glutathione Transferase / Q000302:isolation & purification / Q000378:metabolism*; D006793:Houseflies / Q000201:enzymology*; D007305:Insecticide Resistance; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism; D009284:Naphthols / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity
D007527:Isoenzymes; D009284:Naphthols; C027876:alpha-naphthyl acetate; D005982:Glutathione Transferase