title: [Antineutrophil cytoplasmic antibodies and Wegener's granulomatosis].
abstract: In the presented case are described the clinic demonstrations, analytical and evolutionary in a diagnosed patient of Wegener Granulomatosis (WG). The biopsies practiced in the injuries of the nasal mucous and oral cavity demonstrated a necrotizing granulomatous vasculitis. The antineutrophil cytoplasmic antibodies with standard cytoplasmic (AANC-C) determined by immunofluorescence indirect were positive with a seric initial of 1:160 in the making negative to the sixty treatment days. The administration of the treatment coincided with an improvement meaningful clinic. We emphasize the scarce demonstration of the WG in the oral cavity as well as of the presentation histological described. Finally, we emphasize the growing importance of the AANC-C not only in the diagnosis of the disease but as specific marker of its activity.
authors.affiliation: Servicio de Medicina Interna, Hospital Clínico Universitario, Valencia.
authors.forename: F
authors.initials: F
authors.lastname: Gabriel Botella
authors.forename: M
authors.initials: M
authors.lastname: Labios Gómez
authors.forename: M
authors.initials: M
authors.lastname: Arnal Babiloni
authors.forename: C
authors.initials: C
authors.lastname: Dasi Martínez
authors.forename: R
authors.initials: R
authors.lastname: Vicente Ull
authors.forename: L
authors.initials: L
authors.lastname: Mainar Latorre
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers; D003593:Cytoplasm / Q000276:immunology*; D014890:Granulomatosis with Polyangiitis / Q000276:immunology*; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D015415:Biomarkers
vernacular_title: Anticuerpos anticitoplasma de neutrófilo y granulomatosis de Wegener.