title: [Cerebral venous thromboses: study of the course].
abstract: The management of patients with presumed cerebral venous thrombosis has been recently modified by magnetic resonance imaging and evidence that heparin decreases mortality and morbidity. No large consecutive series of patients with cerebral venous thrombosis has been reported since then. The aim of our study was to determine the prognosis factors of patients with cerebral venous thrombosis. Demographic, clinical and radiological characteristics were recorded in a homogeneous series of 18 consecutive patients with cerebral venous thrombosis collected over a 31-month period. All patients were treated by heparin at the acute stage. We found no difference in demographic, clinical and radiological characteristics of the patients according to the 1-month and 6-month outcome. We only found a tendency towards a better 1-month outcome in younger patients (p = 0.06) and in patients with an isolated intracranial hypertension (2p = 0.06). A long therapeutic delay might be a factor of poor prognosis which might be hidden by a better spontaneous outcome in patients with isolated intracranial hypertension in whom the diagnostic delay is longer. A multicentric study allowing a multivariate analysis may therefore be useful to identify prognosis factors in patients with cerebral venous thrombosis.
authors.affiliation: Service de Neurologie B, Centre Hospitalier Régional et Universitaire de Lille.
authors.forename: P
authors.initials: P
authors.lastname: Rondepierre
authors.forename: M
authors.initials: M
authors.lastname: Hamon
authors.forename: D
authors.initials: D
authors.lastname: Leys
authors.forename: X
authors.initials: X
authors.lastname: Leclerc
authors.forename: F
authors.initials: F
authors.lastname: Mounier-Vehier
authors.forename: O
authors.initials: O
authors.lastname: Godefroy
authors.forename: E
authors.initials: E
authors.lastname: Janssens
authors.forename: J P
authors.initials: JP
authors.lastname: Pruvo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013997:Time Factors
vernacular_title: Thromboses veineuses cérébrales: étude de l'évolution.