Treatment of corticosteroid-azathioprine resistant autoimmune hepatitis with cyclosporin A.
A 33-year-old woman with autoimmune hepatitis developed resistance to prednisolone-azathioprine treatment. A switch to cyclosporin A resulted in immediate remission which was maintained for more than one year. No significant side effect was encountered. Cyclosporin A may be an alternative treatment for patients with autoimmune hepatitis who are resistant to conventional treatment.
Senturk
H
H
Department of Internal Medicine, Cerrahpasa Medical Faculty of Istanbul University, Turkey.
D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy*; D001379:Azathioprine / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D006505:Hepatitis / Q000188:drug therapy* / Q000276:immunology*; D006801:Humans; D008099:Liver / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use
D016572:Cyclosporine; D011239:Prednisolone; D001379:Azathioprine