Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates).
BUA compiled the available data on toxicity and ecotoxicity for several acrylic and methacrylic acid esters and their corresponding acids. A comparison of these data revealed a qualitative similarity in the toxicological and ecotoxicological properties of the compounds considered. The data indicate that methacrylates are less reactive than the corresponding acrylates.
Greim
H
H
GSF Institut für Toxikologie, Oberschleissheim, Germany.
Ahlers
J
J
Bias
R
R
Broecker
B
B
Hollander
H
H
Gelbke
H P
HP
Jacobi
S
S
Klimisch
H J
HJ
Mangelsdorf
I
I
Mayr
W
W
D000179:Acrylates / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D001419:Bacteria / Q000187:drug effects; D001673:Biodegradation, Environmental; D002273:Carcinogens / Q000633:toxicity; D003621:Daphnia / Q000187:drug effects; D056890:Eukaryota / Q000187:drug effects; D005399:Fishes; D006801:Humans; D007928:Lethal Dose 50; D008689:Methacrylates / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D051381:Rats; D012867:Skin / Q000187:drug effects; D013329:Structure-Activity Relationship
D000179:Acrylates; D002273:Carcinogens; D008689:Methacrylates; C008384:methacrylic acid; C036658:acrylic acid