[Different use of thrombolytic therapy in men and women with acute myocardial infarction].
Previous studies have reported a difference between the use of invasive therapeutic procedures in men and women with coronary artery disease. The aim of this study was to evaluate if this difference also exists in the initial treatment of acute myocardial infarction and for numbers of non-invasive procedures performed. We examined 448 patients (283 men and 165 women). We found a significant gender difference concerning the numbers treated with streptokinase, namely 47.3% of the men compared to 33.3% of the women. The delay from onset of symptoms until admission was nearly the same for both sexes. There was, however, a considerably longer in-hospital delay before start of treatment for the women compared to the men. The time-difference was significant for patients below 70 years of age. We found no gender difference in the numbers of performed exercise-tests and echocardiographic examinations. There was a slightly non-significant higher mortality among the women. We also calculated the numbers of patients without contraindications to treatment with streptokinase who were not treated, here we found no difference between the sexes. We conclude that women with symptoms suggesting acute myocardial infarction should be carefully evaluated immediately after admission to hospital to improve thrombolytic therapy.
Thorup
M Z
MZ
Svendborg Sygehus, medicinsk afdeling.
Markenvard
J D
JD
Hansen
A
A
D000368:Aged; D000075202:Contraindications; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D012189:Retrospective Studies; D012737:Sex Factors; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy
D013300:Streptokinase
Forskelsbehandling af maend og kvinder i anvendelse af trombolyse ved akut myokardieinfarkt.