title: Intracranial extension of sphenoid sinusitis.
abstract: BACKGROUND
  The incidence of sphenoid sinusitis has decreased significantly since the pre-antibiotic era. Intracranial complications from isolated sphenoid sinusitis are rare but have a high morbidity and mortality.
  
  
  METHODS
  A case of intracranial extension of sphenoid sinusitis in a 64-year-old woman is reported.
  
  
  RESULTS
  A 64-year-old woman was initially seen unconscious with bacterial meningitis and cerebrospinal fluid (CSF) fistula. Imaging suggested sphenoid sinusitis with intracranial extension. She underwent a sinus drainage procedure, was placed on antibiotic therapy, and underwent a definitive sphenoid sinus obliteration. The patient made a satisfactory recovery.
  
  
  CONCLUSIONS
  Despite the low incidence of intracranial complications of sphenoid sinusitis, the potential morbidity and mortality from such complications is high. We advocate aggressive management consisting of antibiotic therapy, sinus drainage, and definitive CSF fistula repair.
authors.affiliation: Department of Neurosurgery, Royal Melbourne Hospital, Parkville, Victoria, Australia.
authors.forename: C
authors.initials: C
authors.lastname: Xenos
authors.forename: J V
authors.initials: JV
authors.lastname: Rosenfeld
authors.forename: S M
authors.initials: SM
authors.lastname: Kleid
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology; D003131:Combined Modality Therapy; D004322:Drainage; D005260:Female; D005402:Fistula / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D015524:Sphenoid Sinusitis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents