The molecular design of human IL-6 receptor antagonists.
Lahm
A
A
Istituto di Ricerche di Biologia Molecolare P. Angeletti (IRBM), Pomezia, Rome, Italy.
Savino
R
R
Salvati
A L
AL
Cabibbo
A
A
Ciapponi
L
L
Demartis
A
A
Toniatti
C
C
Paonessa
G
G
Altamura
S
S
Ciliberto
G
G
D000595:Amino Acid Sequence; D015703:Antigens, CD; D050822:Cytokine Receptor gp130; D006801:Humans; D015850:Interleukin-6 / Q000737:chemistry* / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D017434:Protein Structure, Tertiary; D018123:Receptors, Interleukin / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D019947:Receptors, Interleukin-6; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013329:Structure-Activity Relationship
D015703:Antigens, CD; C494199:IL6ST protein, human; D015850:Interleukin-6; D008562:Membrane Glycoproteins; D018123:Receptors, Interleukin; D019947:Receptors, Interleukin-6; D050822:Cytokine Receptor gp130