Scalp cyst with heterotopic brain tissue.
A multilocular scalp lesion was noticed at birth in a female infant. There was no underlying skull defect. Histological examination revealed neural tissue staining with S-100 and GFAP, but not with a neurofilament stain, which is in keeping with a glial cell origin. Heterotopic brain tissue is a rare developmental abnormality, which usually has no effect on neurological development. It should be considered in the differential diagnosis of scalp lesions in neonates.
Pryce
D W
DW
Department of Dermatology, Royal Liverpool Children's Hospital, U.K.
Khine
M
M
Verbov
J L
JL
Van Velzen
D
D
D001921:Brain / Q000473:pathology; D002828:Choristoma / Q000151:congenital* / Q000473:pathology; D003560:Cysts / Q000151:congenital* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D009457:Neuroglia / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis; D012536:Scalp Dermatoses / Q000151:congenital* / Q000473:pathology
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins