title: [The production of erythrogenic toxin and the epidemic process in respiratory streptococcal infection].
abstract: The capacity of Streptococcus pyogenes, isolated from clinically healthy children in a large organized group, for producing erythrogenic toxin A, B and C was studied. The dynamics of toxin production was compared with changes in the levels of morbidity and carrier state, as well as with some characteristics of the interaction between the populations of the infective agent and the host by such values as virulence and susceptibility. Similarity in the dynamics of the parameters under study was noted. The seasonal dynamics of characteristics which determined the capacity for toxin production significantly influenced the levels and one year morbidity dynamics with respiratory streptococcal infection. The study demonstrated the information value of the characteristics of toxin production for understanding both the interval mechanisms of the epidemic process and the influence of the external ones on subsequent epidemic situation.
authors.forename: N I
authors.initials: NI
authors.lastname: Briko
authors.forename: V V
authors.initials: VV
authors.lastname: Zhukov
authors.forename: L O
authors.initials: LO
authors.lastname: Dynga
authors.forename: A S
authors.initials: AS
authors.lastname: Eshchina
authors.forename: H
authors.initials: H
authors.lastname: Knol
authors.forename: D
authors.initials: D
authors.lastname: Gerlach
authors.forename: W
authors.initials: W
authors.lastname: Keller
authors.forename: V D
authors.initials: VD
authors.lastname: Beliakov
mesh_terms: D001426:Bacterial Proteins / Q000097:blood*; D002165:Camping; D002353:Carrier State / Q000097:blood / Q000453:epidemiology; D002648:Child; D004196:Disease Outbreaks; D005098:Exotoxins / Q000097:blood*; D006801:Humans; D015994:Incidence; D008565:Membrane Proteins; D012141:Respiratory Tract Infections / Q000097:blood* / Q000453:epidemiology; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D012621:Seasons; D013290:Streptococcal Infections / Q000097:blood* / Q000453:epidemiology; D013297:Streptococcus pyogenes; D013997:Time Factors
chemical_list: D001426:Bacterial Proteins; D005098:Exotoxins; D008565:Membrane Proteins; C117980:SpeA protein, Streptococcus pyogenes; C027951:erythrogenic toxin
vernacular_title: Produktsiia éritrogennogo toksina i épidemicheskiĭ protsess respiratornoĭ streptokokkovoĭ infektsii.