Ganglioglioma of the brain stem: neurological dysfunction of 16-year duration.
An autopsy case of a brain stem ganglioglioma in a 38-year-old male patient with neurological dysfunction of 16-year duration is reported. Immunohistochemical investigation of the tumor was performed using a panel of antibodies against neurofilament protein (NFP), synaptophysin (SY 38), beta-tubulin (TUJ1), neuron specific enolase (NSE), and glial fibrillary acidic protein (GFAP). The value of these markers in the establishment of the diagnosis, as well as the general features, the prognosis and the therapeutic approach of the gangliogliomas are discussed.
Karamitopoulou
E
E
Cantonal Institute of Pathology, Liestal, Switzerland.
Perentes
E
E
Probst
A
A
Wegmann
W
W
D000328:Adult; D000918:Antibody Specificity; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000503:physiopathology; D001933:Brain Stem / Q000737:chemistry / Q000473:pathology* / Q000503:physiopathology; D018303:Ganglioglioma / Q000737:chemistry / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male