[Changes in serum IL-2 and sIL-2R levels in patients with primary hepatic carcinoma before and after treatment and their clinical significance].
Serum IL-2 and sIL-2R levels were measured with sandwith ELISA assay before and after surgery or transarterial embolization in 19 cases of primary hepatic carcinoma. The results show that pretreatment IL-2 levels of patients were significantly lower and sIL-2R expression was higher than those of normal control. IL-2 levels of patient were increased and sIL-2R expression was decreased after treatment. The results suggest that the changes of IL-2 level and sIL-2R expression may be closely related to treatment, recurrence and prognosis of patients with primary hepatic carcinoma.
Wang
M
M
Department of Surgical Oncology, First Affiliated Hospital Zhejiang Medical University, Hangzhou.
Feng
Y
Y
Zhou
X
X
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000097:blood* / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007376:Interleukin-2 / Q000097:blood*; D008113:Liver Neoplasms / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015375:Receptors, Interleukin-2 / Q000378:metabolism*
D007376:Interleukin-2; D015375:Receptors, Interleukin-2