[Immunizing and immunomodulating activity of a wild epidemic parotitis virus at a parotitis infection focus].
The immune status of 18 children previously vaccinated or not with live parotitis vaccine and living in a focus of parotitis was tested over time. Specific antibodies were found in the blood sera or nasal secretion of 88.9% children by follow-up days 10-20, and memory antigen-reactive cells were forming in 55.6%. Functional temporary T-immunodeficiency was observed at the same period in 66.7% children. Although there were no cases of clinically apparent epidemic parotitis, immunologic studies confirmed the circulation of wild type virus. Immunologic studies detected 2 cases of inapparent course of epidemic parotitis.
Iuminova
N V
NV
Krasnova
V P
VP
Glazkova
N V
NV
D000914:Antibodies, Viral / Q000032:analysis / Q000097:blood; D002648:Child; D004197:Disease Reservoirs; D006801:Humans; D007156:Immunologic Memory; D009107:Mumps / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D009297:Nasal Mucosa / Q000276:immunology / Q000378:metabolism; D018108:Respirovirus / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D014765:Viral Vaccines / Q000627:therapeutic use*
D000914:Antibodies, Viral; D014765:Viral Vaccines
Immuniziruiushchaia i immunomoduliruiushchaia aktivnost' dikogo virusa épidemicheskogo parotita v ochage parotitnoĭ infektsii.