title: [Torsade de pointes during anti-arrhythmia treatment with amiodarone].
abstract: Torsade de pointes, a polymorphous ventricular tachycardia, is a well-known but rarely occurring cardiac adverse drug reaction under amiodarone, a class-III antiarrhythmic agent. We report the case of a 60-year-old male patient who developed a life-threatening torsade after three weeks of amiodarone therapy. Considering some potential risk factors, amiodarone is an effective and safe antiarrhythmic agent for ventricular and supraventricular tachycardia. In most patients, Amiodarone can be used safely even in those who had developed a torsade de pointes with other antiarrhythmic agents.
authors.affiliation: Departement Innere Medizin, Abteilung Klinische Pharmakologie, Kantonsspital, Basel.
authors.forename: R G
authors.initials: RG
authors.lastname: Schlienger
authors.forename: W E
authors.initials: WE
authors.lastname: Haefeli
authors.forename: T F
authors.initials: TF
authors.lastname: Lüscher
mesh_terms: D000638:Amiodarone / Q000009:adverse effects* / Q000627:therapeutic use; D005117:Cardiac Complexes, Premature / Q000188:drug therapy; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D000638:Amiodarone
vernacular_title: Torsade de pointes unter antiarrhythmischer Behandlung mit Amiodaron.