title: Genomic structure of the human TATA-box-binding protein (TBP).
abstract: The gene encoding the human TATA-box-binding protein (hTBP) is contained within a 20-kb DNA fragment and is split into eight exons. The coding sequence is interrupted by six introns and the 5'-untranslated region (5'-UTR) of the gene by a 2.5-kb intron. A comparison of the hTBP exon/intron organization with the various TBP cloned to date is presented.
authors.affiliation: Institute de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, C.U. de Strasbourg, France.
authors.forename: C
authors.initials: C
authors.lastname: Chalut
authors.forename: Y
authors.initials: Y
authors.lastname: Gallois
authors.forename: A
authors.initials: A
authors.lastname: Poterszman
authors.forename: V
authors.initials: V
authors.lastname: Moncollin
authors.forename: J M
authors.initials: JM
authors.lastname: Egly
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D005091:Exons; D005260:Female; D015894:Genome, Human; D006801:Humans; D007438:Introns; D051379:Mice; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011247:Pregnancy; D017434:Protein Structure, Tertiary; D013045:Species Specificity; D016385:TATA Box; D035181:TATA-Box Binding Protein; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D035181:TATA-Box Binding Protein; D014157:Transcription Factors