title: [Radioiodine therapy of funcitonal autonomy using the functional autonomous volume].
abstract: In order to determine the effective radiation dose to be delivered by 131I in functional autonomy we have used the functional autonomous volume calculated from the global 99mTc thyroid uptake under exogenous or endogenous suppression before and 3 to 7 months after treatment. The radiation dose to the autonomous volume was calculated retrospectively in 131 patients with unifocal, multifocal and disseminated autonomy (75 hyperthyroid, 56 euthyroid) who received 131I treatment of 200-300 Gy to the total volume of the gland. It could be shown that at least 350 Gy to the autonomous volume are required to reach the desired effect of treatment which was dependent only on the radiation dose delivered to the functional autonomous volume.
authors.affiliation: Abteilung für Nuklearmedizin, Zentrum Radiologie, Universität Göttingen, FRG.
authors.forename: T
authors.initials: T
authors.lastname: Seeger
authors.forename: D
authors.initials: D
authors.lastname: Emrich
authors.forename: D
authors.initials: D
authors.lastname: Sandrock
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000503:physiopathology* / Q000532:radiotherapy*; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013667:Technetium; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
chemical_list: D007457:Iodine Radioisotopes; D014284:Triiodothyronine; D013973:Thyrotropin-Releasing Hormone; D013667:Technetium; D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Radiojodtherapie der funktionellen Autonomie unter Verwendung des funktionellen autonomen Volumens.