A case report suggesting a common pathogenesis for IgA nephropathy and Henoch-Schönlein purpura.
A 7-year-old boy who had been followed for asymptomatic haematuria and elevated serum IgA levels developed Henoch-Schönlein purpura (HSP) after a streptococcal infection of the tonsils. Findings on renal biopsy were compatible with mild IgA nephropathy (IgAN); tonsillectomy was also performed as he had chronic tonsillitis. This case suggests that there is a common pathogenesis for IgAN and HSP, at least in some patients.
Kaneko
K
K
Department of Paediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Suzuki
Y
Y
Kiya
K
K
Fukuda
Y
Y
Yabuta
K
K
D002648:Child; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000473:pathology; D006417:Hematuria / Q000150:complications; D006801:Humans; D011695:IgA Vasculitis / Q000209:etiology*; D007070:Immunoglobulin A / Q000097:blood; D008297:Male; D013290:Streptococcal Infections / Q000150:complications / Q000276:immunology*; D014069:Tonsillitis / Q000150:complications / Q000276:immunology*
D007070:Immunoglobulin A