Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model.
Meiser
B M
BM
Department of Cardiac Surgery, Ludwig Maximilians University of Munich, Germany.
Wenke
K
K
Thiery
J
J
Wolf
S
S
Devens
C
C
Seidel
D
D
Hammer
C
C
Billingham
M E
ME
Reichart
B
B
D000818:Animals; D001161:Arteriosclerosis / Q000139:chemically induced / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D003404:Creatinine / Q000097:blood; D006085:Graft Survival / Q000187:drug effects; D016027:Heart Transplantation / Q000276:immunology / Q000473:pathology* / Q000502:physiology; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008148:Lovastatin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D019821:Simvastatin; D016559:Tacrolimus / Q000627:therapeutic use / Q000633:toxicity*; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002784:Cholesterol; D008148:Lovastatin; D019821:Simvastatin; D003404:Creatinine; D016559:Tacrolimus