[Extracted hemoglobins as oxygen transporters: proposal of a hemoglobin-dextran-benzenetetracarboxylate conjugate].
The implication of blood in HIV and other viruses transmission has invigorated the research for finding a fluid able to replace blood as regards its oxygen-carrying properties. In this work, the specifications of a potential substitute are first defined. Then, the means to be developed in order to match these specifications at best are precise. Afterwards, a possible oxygen-carrier, the hemoglobin-dextran-BTC conjugate, is described.
Vigneron
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Centre Régional de Transfusion Sanguine et d'Hématologie, Vandoeuvre-les-Nancy.
D001565:Benzoates / Q000737:chemistry*; D001692:Biological Transport / Q000502:physiology; D001802:Blood Substitutes / Q000378:metabolism*; D002474:Cell-Free System / Q000378:metabolism; D003911:Dextrans / Q000737:chemistry*; D006454:Hemoglobins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D010084:Oxidation-Reduction; D010100:Oxygen / Q000097:blood*; D012996:Solutions
D001565:Benzoates; D001802:Blood Substitutes; D003911:Dextrans; D006454:Hemoglobins; D012996:Solutions; C012018:pyromellitic acid; D010100:Oxygen