Experimental investigations concerning a new liquid embolization method: combined administration of ethanol-estrogen and polyvinyl acetate.
A new embolization agent combining ethanol-estrogen and polyvinyl acetate was evaluated angiographically and histologically in 18 canine renal arterial systems. Peripheral vessels of less than 100 microns diameter were obliterated by thrombus induced by ethanol-estrogen, and larger vessels were obliterated by polyvinyl acetate casts and/or thrombus. This embolization method is easily controlled and has fewer adverse effects, so is suitable for intravascular applications, especially in the head and neck regions.
Sugawara
T
T
Department of Neurosurgery, Kohnan Hospital, Sendai.
Takahashi
A
A
Su
C C
CC
Suga
T
T
Yoshimoto
T
T
D000818:Animals; D002404:Catheterization; D004285:Dogs; D004338:Drug Combinations; D004621:Embolization, Therapeutic / Q000379:methods*; D004967:Estrogens / Q000008:administration & dosage / Q000627:therapeutic use*; D000431:Ethanol / Q000008:administration & dosage / Q000627:therapeutic use*; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D011145:Polyvinyls / Q000008:administration & dosage / Q000627:therapeutic use*; D011859:Radiography; D012077:Renal Artery / Q000000981:diagnostic imaging
D004338:Drug Combinations; D004967:Estrogens; D011145:Polyvinyls; C013215:polyvinyl acetate; D000431:Ethanol