Production of prostatic lesions in canines using transrectally administered high-intensity focused ultrasound.
High-intensity focused ultrasound is a method of destroying tissue at a point distant from the transducer without injuring intervening tissue. A transrectal probe was developed and used to treat 26 canines in order to determine the feasibility of using this therapy in humans. Lesions of coagulative necrosis which evolved into cystic cavities were produced. Surrounding tissue was preserved without evidence of injury.
Foster
R S
RS
Department of Urology, Indiana University Medical Center, Indianapolis 46202-5250.
Bihrle
R
R
Sanghvi
N
N
Fry
F
F
Kopecky
K
K
Regan
J
J
Eble
J
J
Hennige
C
C
Hennige
L V
LV
Donohue
J P
JP
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005240:Feasibility Studies; D007668:Kidney / Q000473:pathology; D008297:Male; D011467:Prostate / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000097:blood / Q000473:pathology / Q000628:therapy*; D012007:Rectum / Q000473:pathology; D013813:Therapy, Computer-Assisted; D014464:Ultrasonic Therapy