Porokeratosis of Mibelli associated with active chronic hepatitis and vitiligo.
A patient with porokeratosis Mibelli is reported who suffered from long-standing chronic active hepatitis and rapidly expanding vitiligo of more recent onset. This type of disease association has never been reported before, although it is in line with several reports of porokeratosis in association with immunoregulatory disorders, mostly after drug-induced immunosuppression. The lesions of the present patient responded well to treatment with topical 5-fluorouracil.
Dippel
E
E
Department of Dermatology, Clinics Rudolf Virchow, Free University Berlin, Germany.
Haas
N
N
Czarnetzki
B M
BM
D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006521:Hepatitis, Chronic / Q000150:complications* / Q000473:pathology; D006801:Humans; D007868:Leg Dermatoses / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D017499:Porokeratosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D014820:Vitiligo / Q000150:complications* / Q000473:pathology
D005472:Fluorouracil