[Level of macrophages and lymphocytes reacting with nitro-tetrazole blue (NBT) in mice infected with Yersinia enterocolitica].
The study was aimed at investigation of reducing ability of nitrotetrazol blue (NBT) by peritoneal fluid macrophages and spleen and mesenteric lymph node during experimental yersiniosis. Investigations were carried on BALB/c mice infected perorally by the dose of 10(6) of live, virulent cells of Y. enterocolitica. It was found that clear increase of metabolic activity in macrophages occurred between 3 and 12 day after infection, in spleen lymphocytes between 6 and 9 day, whereas it was noted in mesenteric lymph node between 6 and 15 day after infection. Maximal stimulation of macrophages was observed at the 6th day of lymphocytes on 9th day after infection. These results suggest that macrophages are the first cells which react to infection with Y. enterocolitica. Activity of spleen and mesenteric lymph node lymphocytes during first days of infection appeared relatively small.
Staroniewicz
Z
Z
Katedra Mikrobiologii Wydziału Medycyny Weterynaryjnej AR, Wrocławiu.
D000818:Animals; D001202:Ascitic Fluid / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D008643:Mesentery; D051379:Mice; D008807:Mice, Inbred BALB C; D013154:Spleen / Q000276:immunology; D013194:Staining and Labeling; D015009:Yersinia Infections / Q000276:immunology*; D015008:Yersinia enterocolitica