Comparison of serological tests and bio-assay for malaria transmission blocking capacity in field sera.
Competition ELISAs have been developed for natural transmission blocking antibodies. Approximately 50% of the sera blocking in the conventional mosquito feeding experiments, gave positive results in these competition ELISAs. Attempts to adapt competition ELISAs to a field application have been partly successful.
Roeffen
W
W
University of Nijmegen, Department of Medical Microbiology, The Netherlands.
Beckers
P J
PJ
Teelen
K
K
Verhave
J P
JP
Eling
W
W
Sauerwein
R
R
D000818:Animals; D000852:Anopheles / Q000469:parasitology; D000913:Antibodies, Protozoan / Q000097:blood* / Q000276:immunology; D000953:Antigens, Protozoan / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology; D001681:Biological Assay; D002353:Carrier State / Q000097:blood* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000276:immunology; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D016778:Malaria, Falciparum / Q000097:blood* / Q000635:transmission; D010963:Plasmodium falciparum / Q000276:immunology* / Q000302:isolation & purification; D015800:Protozoan Proteins / Q000276:immunology*
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D000954:Antigens, Surface; D000939:Epitopes; D015800:Protozoan Proteins