title: HeLa D98/aH-2 studied by chromosome painting and conventional cytogenetical techniques.
abstract: Metaphase chromosomes of HeLa D98/AH-2 cells were studied by GTG-banding, NOR-silver staining and in situ hybridization using libraries specific for each human chromosome as probes (chromosome painting). The structure and composition of all marker chromosomes could be determined, allowing a critical assessment of earlier studies. The revised HeLa D98/AH-2 karyotype should provide a reference standard in certain cancer cytogenetic studies.
authors.affiliation: Deutsches Krebsforschungs-Zentrum, Heidelberg, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Ruess
authors.forename: L Z
authors.initials: LZ
authors.lastname: Ye
authors.forename: C
authors.initials: C
authors.lastname: Grond-Ginsbach
mesh_terms: D002871:Chromosome Banding; D002877:Chromosomes, Human; D003582:Cytogenetics; D005819:Genetic Markers; D005821:Genetic Techniques; D006367:HeLa Cells / Q000648:ultrastructure*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D013194:Staining and Labeling
chemical_list: D005819:Genetic Markers