title: [Doppler ultrasound results of hemodilution treatment].
abstract: In a double-blind study, 12 patients with an Hb > 13 g/dl in the second trimester, a pretherapeutic hematocrit > 38%, and a fetal aortal resistance index > 0.75 underwent hemodilution. The patients were given either 500 ml hydroxyethyl starch (HAES) or 500 ml NaCl 0.9%. In addition, all patients received 500 ml NaCl 0.9% by infusion. HAES therapy caused a lowering of the fetal aortal and uterine artery resistance indices. This was not the case with NaCl. The causes for this lie in the specific anti-aggregation and viscosity-reducing effect of hydroxyethyl starch with an identical lowering of hematocrit.
authors.affiliation: Abtl. Gynäkologie und Geburtshilfe, Stadtkrankenhaus Rüsselsheim.
authors.forename: L
authors.initials: L
authors.lastname: Heilmann
authors.forename: G F
authors.initials: GF
authors.lastname: von Tempelhoff
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D004311:Double-Blind Method; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging / Q000628:therapy*; D005865:Gestational Age; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D010927:Placental Insufficiency / Q000000981:diagnostic imaging / Q000628:therapy*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D006895:Hydroxyethyl Starch Derivatives