Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway.
Goeptar
A R
AR
Leiden/Amsterdam Center for Drug Research, Department of Pharmacochemistry, Vrije Universiteit, The Netherlands.
Commandeur
J N
JN
van Ommen
B
B
van Bladeren
P J
PJ
Vermeulen
N P
NP
D000107:Acetylation; D000111:Acetylcysteine / Q000378:metabolism*; D000818:Animals; D001711:Biotransformation; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D007680:Kidney Neoplasms / Q000139:chemically induced; D008113:Liver Neoplasms / Q000139:chemically induced; D008175:Lung Neoplasms / Q000139:chemically induced; D009369:Neoplasms / Q000139:chemically induced*; D013045:Species Specificity; D014241:Trichloroethylene / Q000378:metabolism* / Q000633:toxicity*
D014241:Trichloroethylene; D005978:Glutathione; D000111:Acetylcysteine