title: S100 protein and neuron-specific enolase on monocytic leukemic CD1+ cells, probable precursors of Langerhans cells.
abstract: Langerhans cells are characterized by specific markers, such as Birbeck granules and CD1a antigen. S100 protein and neuron-specific enolase are less specific but are expressed only on Langerhans cells among the cells of the phagocytic mononuclear system. In this study, the expression of these two antigens on many monocytic leukemic cells is shown. These cells could be precursors of Langerhans cells which have been transformed into malignant cells.
authors.affiliation: INSERM U 346, Hôpital Edouard Herriot, Lyon, France.
authors.forename: L
authors.initials: L
authors.lastname: Misery
authors.forename: L
authors.initials: L
authors.lastname: Campos
authors.forename: O
authors.initials: O
authors.lastname: Sabido
authors.forename: J
authors.initials: J
authors.lastname: Kanitakis
authors.forename: C
authors.initials: C
authors.lastname: Dezutter-Dambuyant
authors.forename: D
authors.initials: D
authors.lastname: Guyotat
authors.forename: D
authors.initials: D
authors.lastname: Schmitt
mesh_terms: D015703:Antigens, CD / Q000032:analysis*; D018949:Antigens, CD1; D006801:Humans; D007801:Langerhans Cells / Q000737:chemistry* / Q000276:immunology; D007948:Leukemia, Monocytic, Acute / Q000276:immunology* / Q000473:pathology; D015479:Leukemia, Myelomonocytic, Acute / Q000276:immunology / Q000473:pathology; D010751:Phosphopyruvate Hydratase / Q000032:analysis*; D009418:S100 Proteins / Q000032:analysis*; D013234:Stem Cells / Q000737:chemistry / Q000276:immunology
chemical_list: D015703:Antigens, CD; D018949:Antigens, CD1; D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase