title: Anti-HCV seroprevalence in pregnant women in France.
abstract: In a study designed to assess the prevalence of antibodies to hepatitis C virus (HCV) in pregnant women, anti-HCV positivity in French pregnant women was twice as high as that found in French blood donors. Positive ELISA 2 results were confirmed by positive RIBA 2 in most subjects, and seven of nine RIBA 2 positive patients also tested positive for HCV-RNA by PCR. High rates of anti-HCV positivity were seen among immigrant pregnant women, partly because of false positive results with ELISA 2. RIBA 2 results suggested that the prevalence of HCV infection was not any higher in immigrant compared with French pregnant women.
authors.affiliation: Département d'Epidémiologie, Hôpital Henri Mondor, Créteil, France.
authors.forename: F
authors.initials: F
authors.lastname: Roudot-Thoraval
authors.forename: J M
authors.initials: JM
authors.lastname: Pawlotsky
authors.forename: L
authors.initials: L
authors.lastname: Deforges
authors.forename: P P
authors.initials: PP
authors.lastname: Girollet
authors.forename: D
authors.initials: D
authors.lastname: Dhumeaux
mesh_terms: D000328:Adult; D004641:Emigration and Immigration; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D005602:France / Q000453:epidemiology; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology*; D018937:Hepatitis C Antibodies; D006801:Humans; D015151:Immunoblotting; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology*; D012307:Risk Factors
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies