Antiinflammatory and analgesic activity of CP-96,345: an orally active non-peptide substance P receptor antagonist.
Nagahisa
A
A
Department of Medicinal Biology, Pfizer Inc., Aichi, Japan.
Kanai
Y
Y
Suga
O
O
Taniguchi
K
K
Tsuchiya
M
M
Lowe
J A
JA
Hess
H J
HJ
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000494:pharmacology*; D001920:Bradykinin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005070:Evans Blue; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D017998:Leukotriene D4 / Q000494:pharmacology; D008297:Male; D015288:Neurokinin A / Q000494:pharmacology; D015287:Neurokinin B / Q000494:pharmacology; D064729:Neurokinin-1 Receptor Antagonists; D010972:Platelet Activating Factor / Q000494:pharmacology; D018040:Receptors, Neurokinin-1 / Q000502:physiology; D012867:Skin / Q000098:blood supply*; D013373:Substance P / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D014513:Ureter / Q000187:drug effects / Q000502:physiology*
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001713:Biphenyl Compounds; D064729:Neurokinin-1 Receptor Antagonists; D010972:Platelet Activating Factor; D018040:Receptors, Neurokinin-1; D013373:Substance P; D005070:Evans Blue; D017998:Leukotriene D4; D006632:Histamine; D015288:Neurokinin A; D015287:Neurokinin B; D001920:Bradykinin; C066892:CP 96345