title: Histological and mucin secretion patterns in solitary rectal ulcer syndrome.
abstract: OBJECTIVE
  Histological and mucin secretion patterns were studied in 32 cases of solitary rectal ulcer syndrome.
  
  
  METHODS
  Biopsy sections stained with hematoxylin and eosin, Masson's trichrome and alcian blue with PAS at pH 1.0 and pH 2.5 were examined.
  
  
  RESULTS
  Fibrosis and smooth muscle extension in lamina propria and hypertrophy of muscularis mucosa were the most frequent histological findings. Sialomucin was present in all cases, in contrast to sulphomucin which is normally present.
  
  
  CONCLUSIONS
  Mucin staining pattern appears to be a helpful diagnostic marker of solitary rectal ulcer syndrome and may be helpful in differentiating it from other non-malignant conditions.
authors.affiliation: Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
authors.forename: E M
authors.initials: EM
authors.lastname: Khan
authors.forename: R
authors.initials: R
authors.lastname: Pandey
mesh_terms: D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D009077:Mucins / Q000032:analysis / Q000378:metabolism*; D012002:Rectal Diseases / Q000473:pathology*; D052116:Sialomucins; D013194:Staining and Labeling; D014456:Ulcer / Q000473:pathology
chemical_list: D009077:Mucins; D052116:Sialomucins