[Pulsatile secretion of gonadotropins and prolactin and response to luliberin in female rats after injection of galanin into the third cerebral ventricle].
Galanin injection in a dose 200 ng/2 microliters into the third brain ventricle of ovariectomized Sprague-Dawley rats increased pulsatile release of LH and prolactin but did not influence FSH release. Gonadotropin response to LHRH was unchanged. In ovariectomized estrogen-primed rats (50 micrograms estradiol benzoate 73 h prior to the experiment) galanin stimulating effect on LH secretion was slightly manifest and prolactin and FSH release did not change at all.
Reznikov
A G
AG
MakKénn
S M
SM
Rettori
V
V
D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D019004:Galanin; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007031:Hypothalamus / Q000502:physiology; D007276:Injections, Intraventricular; D007986:Luteinizing Hormone / Q000378:metabolism*; D009479:Neuropeptides / Q000008:administration & dosage / Q000502:physiology*; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology; D010455:Peptides / Q000008:administration & dosage / Q000502:physiology*; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012636:Secretory Rate / Q000187:drug effects
D009479:Neuropeptides; D010455:Peptides; D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D019004:Galanin; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone