title: Reappraisal of the role of liver transplantation in the treatment of hepatocellular carcinoma arising in cirrhosis.
abstract: Several retrospective analyses have recently shown the advantage of liver transplantation (OLT) for patients with hepatocellular carcinoma (HCC) at early tumor stages. Preliminary results of a prospective series of OLT for unresectable small HCC arising in cirrhosis are reported. Eighteen out of 22 patients (82%) are alive without evidence of HCC recurrence after a median follow-up of 11 months.
authors.affiliation: Department of Surgery, Istituto Nazionale Tumori, Milan, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Gennari
authors.forename: V
authors.initials: V
authors.lastname: Mazzaferro
authors.forename: E
authors.initials: E
authors.lastname: Regalia
authors.forename: G
authors.initials: G
authors.lastname: Colella
authors.forename: R
authors.initials: R
authors.lastname: Doci
authors.forename: F
authors.initials: F
authors.lastname: Bozzetti
authors.forename: M
authors.initials: M
authors.lastname: Ammatuna
authors.forename: S
authors.initials: S
authors.lastname: Andreola
authors.forename: F
authors.initials: F
authors.lastname: Montalto
authors.forename: R
authors.initials: R
authors.lastname: Manzi
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006509:Hepatitis B; D006526:Hepatitis C; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000382:microbiology; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D012086:Reoperation; D015996:Survival Rate; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins