Reversible Fanconi syndrome associated with valproate therapy.
Two children with developmental delay and seizure disorders had Fanconi syndrome associated with valproate therapy. Both recovered normal proximal tubular function within 4 months of discontinuing valproate therapy.
Lande
M B
MB
Division of Nephrology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
Kim
M S
MS
Bartlett
C
C
Guay-Woodford
L M
LM
D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000188:drug therapy; D005198:Fanconi Syndrome / Q000139:chemically induced* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid