title: [Changes in the membrane potential of rat peritoneal macrophages under the extracellular action of ATP].
abstract: In rat peritoneal macrophages the patch-clamp technique in whole-cell configuration was used to study modifications of membrane potential as a result of extracellular application of micromolar ATP concentration. The registered changes in membrane potential appeared to be of different form and polarization depending on the presence of Ca2+ in extracellular solution and on the concentration of calcium buffer inside the cell. A mechanism of membrane potential changes and their possible connection with the generation of a Ca2+ signal in the cell are discussed.
authors.forename: A N
authors.initials: AN
authors.lastname: Zubov
authors.forename: L N
authors.initials: LN
authors.lastname: Pisareva
authors.forename: S B
authors.initials: SB
authors.lastname: Semenova
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000502:physiology; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D004533:Egtazic Acid / Q000494:pharmacology; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D018408:Patch-Clamp Techniques; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004533:Egtazic Acid; D000255:Adenosine Triphosphate; D002118:Calcium