title: Isolated limb perfusion with urokinase in the treatment of extensive vascular thrombosis of the lower limbs.
abstract: Isolated limb perfusion with urokinase was used in combination with balloon catheter embolectomy in three patients with extensive vascular thrombosis in the lower limbs after conventional methods of treatment failed to restore perfusion to the lower limb. The technique and its results are described and discussed. It is suggested that isolated limb perfusion with urokinase is safe and is worthy of further investigation in the treatment of critically ischaemic lower limbs.
authors.affiliation: Department of Anaesthetics, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
authors.forename: P C
authors.initials: PC
authors.lastname: Kam
authors.forename: J F
authors.initials: JF
authors.lastname: Thompson
authors.forename: J
authors.initials: J
authors.lastname: May
mesh_terms: D000368:Aged; D000671:Amputation, Surgical; D002404:Catheterization; D017128:Embolectomy / Q000379:methods; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D008297:Male; D010477:Perfusion; D012008:Recurrence; D013927:Thrombosis / Q000188:drug therapy* / Q000601:surgery; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D014568:Urokinase-Type Plasminogen Activator