title: Vascularized bone allografts: review of current concepts.
abstract: Advances in the field of microsurgery over the past two decades, together with the discovery of a powerful immunosuppressive, cyclosporin A, have brought vascularized osteochondral allografts closer to reality. In this review, the authors describe the history of laboratory research on vascularized osteochondral allografts using immunosuppression, as well as their experimental and preliminary clinical experiences.
authors.affiliation: Department of Orthopedic Surgery, Yamaguchi University School of Medicine, Ube, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Doi
authors.forename: T
authors.initials: T
authors.lastname: Akino
authors.forename: M
authors.initials: M
authors.lastname: Shigetomi
authors.forename: K
authors.initials: K
authors.lastname: Muramatsu
authors.forename: S
authors.initials: S
authors.lastname: Kawai
mesh_terms: D000818:Animals; D016025:Bone Transplantation / Q000379:methods* / Q000473:pathology; D002356:Cartilage / Q000637:transplantation; D002675:Child, Preschool; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use; D005360:Fibula / Q000637:transplantation; D006801:Humans; D007596:Joints / Q000637:transplantation; D008297:Male; D008866:Microsurgery / Q000379:methods; D014184:Transplantation, Homologous
chemical_list: D016572:Cyclosporine