Vascularized bone allografts: review of current concepts.
Advances in the field of microsurgery over the past two decades, together with the discovery of a powerful immunosuppressive, cyclosporin A, have brought vascularized osteochondral allografts closer to reality. In this review, the authors describe the history of laboratory research on vascularized osteochondral allografts using immunosuppression, as well as their experimental and preliminary clinical experiences.
Doi
K
K
Department of Orthopedic Surgery, Yamaguchi University School of Medicine, Ube, Japan.
Akino
T
T
Shigetomi
M
M
Muramatsu
K
K
Kawai
S
S
D000818:Animals; D016025:Bone Transplantation / Q000379:methods* / Q000473:pathology; D002356:Cartilage / Q000637:transplantation; D002675:Child, Preschool; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use; D005360:Fibula / Q000637:transplantation; D006801:Humans; D007596:Joints / Q000637:transplantation; D008297:Male; D008866:Microsurgery / Q000379:methods; D014184:Transplantation, Homologous
D016572:Cyclosporine