title: Choroidal and retinal detachment in antineutrophil cytoplasmic antibody-positive scleritis.
abstract: OBJECTIVE
  A 72-year-old woman with antineutrophil cytoplasmic antibody-positive vasculitis had a combined detachment of the choroid and retina. This unique initial manifestation was also associated with systemic and orbital manifestations, including brow ptosis, dacryoadenitis, and pneumonitis.
  
  
  CONCLUSIONS
  This patient underwent vitrectomy for removal of a dense vitreitis and responded well to systemic cyclophosphamide. This case demonstrates that antineutrophil cytoplasmic antibody testing is useful for the diagnosis and treatment of Wegener's granulomatosis and microscopic polyarteritis-associated scleritis. The distinction between these two entities is often difficult to make.
authors.affiliation: Department of Ophthalmology, Medical College of Georgia, Augusta 30912, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Marcus
authors.forename: A R
authors.initials: AR
authors.lastname: Frederick
authors.forename: M B
authors.initials: MB
authors.lastname: Raizman
authors.forename: J W
authors.initials: JW
authors.lastname: Shore
mesh_terms: D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000032:analysis*; D015415:Biomarkers; D015862:Choroid Diseases / Q000209:etiology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis; D006801:Humans; D010488:Polyarteritis Nodosa / Q000175:diagnosis; D012163:Retinal Detachment / Q000209:etiology*; D015423:Scleritis / Q000150:complications / Q000276:immunology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D015415:Biomarkers