Two independent outbreaks of measles in partially vaccinated junior high schools in Tottori, Japan.
We analyzed retrospectively a relative risk of measles attacks in vaccinated vs. unvaccinated students using two independent outbreaks in Japan. The first involved 33/328 (10%) students where 64% students and 30% measles cases had been vaccinated. The second involved 27/241 (11%) students where 81% students and 48% measles cases had been vaccinated. The attack rates of vaccinated vs. unvaccinated students were significantly low (p < 0.001), but they accounted 25% in both episodes. The statistically significant clinical features among vaccinated and unvaccinated cases included the average duration of fever, 5.16 +/- 1.71 vs. 6.67 +/- 2.19 days (p = 0.01) and the incidence of complications, 0 vs. 25%, respectively. These results suggested that the measles in vaccinated cases were mostly due to secondary failures.
Kawamoto
A
A
Tottori Prefectural Public Health Laboratory, Japan.
Honda
T
T
Ishida
K
K
Ozeki
T
T
Hayashibara
H
H
Shiraki
K
K
Hino
S
S
D000293:Adolescent; D002648:Child; D004196:Disease Outbreaks; D006801:Humans; D017589:Immunization Programs; D007117:Immunization, Secondary; D007564:Japan / Q000453:epidemiology; D008457:Measles / Q000453:epidemiology* / Q000517:prevention & control; D008458:Measles Vaccine; D012189:Retrospective Studies; D012306:Risk; D014611:Vaccination
D008458:Measles Vaccine