The mechanism of the neurotoxic effects of spermidine.
Doyle
K M
KM
Department of Pharmacology, School of Pharmacy, Trinity College, Dublin, Ireland.
Shaw
G G
GG
D000818:Animals; D002552:Cerebral Ventricles / Q000187:drug effects / Q000502:physiology; D016291:Dizocilpine Maleate / Q000494:pharmacology; D006146:Guanidines / Q000494:pharmacology; D007276:Injections, Intraventricular; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009043:Motor Activity / Q000187:drug effects*; D009498:Neurotoxins / Q000008:administration & dosage / Q000633:toxicity*; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000037:antagonists & inhibitors; D010880:Piperidines / Q000494:pharmacology; D011700:Putrescine / Q000031:analogs & derivatives / Q000494:pharmacology; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors; D013095:Spermidine / Q000008:administration & dosage / Q000633:toxicity*; D013239:Stereotyped Behavior / Q000187:drug effects*
D006146:Guanidines; D009498:Neurotoxins; D010880:Piperidines; D016194:Receptors, N-Methyl-D-Aspartate; C044445:MDL 72527; D016291:Dizocilpine Maleate; D000587:Oxidoreductases Acting on CH-NH Group Donors; C010739:ifenprodil; C004479:pimagedine; D013095:Spermidine; D011700:Putrescine