title: Porphyria cutanea tarda and antibodies to hepatitis C virus.
abstract: We have studied the prevalence of hepatitis C virus antibodies (anti-HCV) in 13 patients suffering from sporadic porphyria cutanea tarda. The sera were tested by Abbott second-generation enzyme immunoassay; seropositivity was confirmed by Ortho second-generation recombinant immunoblot assay. Ten cases (76.1%) were anti-HCV positive; one patient was also seropositive for HIV. This preliminary study suggests that HCV could be a frequent triggering factor for sporadic porphyria cutanea tarda.
authors.affiliation: Department of Dermatology, University of Nice, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Lacour
authors.forename: I
authors.initials: I
authors.lastname: Bodokh
authors.forename: J
authors.initials: J
authors.lastname: Castanet
authors.forename: S
authors.initials: S
authors.lastname: Bekri
authors.forename: J P
authors.initials: JP
authors.lastname: Ortonne
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000150:complications; D018937:Hepatitis C Antibodies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017119:Porphyria Cutanea Tarda / Q000209:etiology / Q000276:immunology*
chemical_list: D006508:Hepatitis Antibodies; D018937:Hepatitis C Antibodies