title: Charcoal bamboo as a bone substitute: an animal study.
abstract: Charcoal bamboo (Bambusae glaucescens) was placed in the resected tibial diaphysis of sixteen New Zealand White rabbits. At two, four and six weeks and again at six months after the operations, four rabbits in each period were killed and all specimens were examined under a light microscope and a scanning electron microscope. The six-week specimens showed that there was neobone invasion into the pores of the charcoal bamboo. There was no evidence of fibroencapsulation or inflammatory response. Due to its structure as a uniform porous material with interconnecting pores and carbon composition, the charcoal bamboo has been proved to be an osteotropic material.
  
  
  CONCLUSIONS
  Charcoal bamboo should be an alternative bone substitute which may be used in humans in the near future. This material is available and easy to produce and prepare in developing countries.
authors.affiliation: Department of Orthopaedics & Rehabilitation Medicine, Srinagarind Hospital.
authors.forename: W
authors.initials: W
authors.lastname: Kosuwon
authors.forename: W
authors.initials: W
authors.lastname: Laupattarakasem
authors.forename: S
authors.initials: S
authors.lastname: Saengnipanthkul
authors.forename: B
authors.initials: B
authors.lastname: Mahaisavariya
authors.forename: S
authors.initials: S
authors.lastname: Therapongpakdee
mesh_terms: D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D002146:Bony Callus / Q000502:physiology; D002606:Charcoal / Q000627:therapeutic use*; D008422:Materials Testing; D016348:Osseointegration; D010944:Plants; D016062:Porosity; D011817:Rabbits
chemical_list: D018786:Bone Substitutes; D002606:Charcoal