title: Conservative treatment in splenic trauma.
abstract: Conservative management of splenic injuries following blunt abdominal trauma is receiving increasing support following delineation of the role of the spleen in preventing infections. This report describes experience with the treatment of 215 consecutive cases treated between 1982 and 1989. A total of 38 patients underwent non-operative management (NOM), 16 splenorrhaphy, 16 partial splenectomy, 60 splenectomy with autotransplantation and 85 splenectomy alone. All patients, regardless of the treatment received, were assessed before discharge and periodically with a maximum follow-up of 5 years. During the follow-up period immunohaematological studies were performed that demonstrated an almost normal activity in the autotransplantation group when compared with the simple splenectomy group. No major complications were observed in the autotransplantation group; a good function and morphology of the re-implanted splenic tissue was always evident by radioisotopic, echographic and histological studies. A conservative approach should always be considered in splenic trauma. In cases where NOM, splenorrhaphy and partial resection are unsafe, splenectomy with autotransplantation should be considered as this simple and reliable technique allows preservation of splenic function.
authors.affiliation: Department of Emergency Surgery, Cardarelli Hospital, Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tricarico
authors.forename: F
authors.initials: F
authors.lastname: Sicoli
authors.forename: F
authors.initials: F
authors.lastname: Calise
authors.forename: E
authors.initials: E
authors.lastname: Iavazzo
authors.forename: M
authors.initials: M
authors.lastname: Salvatore
authors.forename: L
authors.initials: L
authors.lastname: Mansi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013154:Spleen / Q000293:injuries* / Q000637:transplantation; D013156:Splenectomy / Q000009:adverse effects / Q000706:statistics & numerical data; D014182:Transplantation, Autologous / Q000276:immunology; D014949:Wounds, Nonpenetrating / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging / Q000276:immunology / Q000628:therapy*
chemical_list: D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M