A selective and extremely potent antagonist of the neurokinin-1 receptor.
Sakurada
T
T
Department of Pharmacology, Tohoku College of Pharmacy, Sendai, Japan.
Manome
Y
Y
Tan-No
K
K
Sakurada
S
S
Ohba
M
M
Kisara
K
K
Terenius
L
L
D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007278:Injections, Spinal; D007700:Kinetics; D051379:Mice; D064729:Neurokinin-1 Receptor Antagonists; D010446:Peptide Fragments / Q000008:administration & dosage / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D018040:Receptors, Neurokinin-1 / Q000502:physiology; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D013373:Substance P / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*
D000700:Analgesics; D064729:Neurokinin-1 Receptor Antagonists; D010446:Peptide Fragments; D018040:Receptors, Neurokinin-1; D013373:Substance P; C032292:substance P (6-11); D011761:Pyrrolidonecarboxylic Acid