Cytogenetic damage and occupational exposure: II. Exposure to petroleum exhaust.
A cytogenetic survey was conducted on personnel exposed to petroleum exhaust fumes (vapour and smoke at automobile workshops). The incidence of chromosomal aberrations (CAs) in this population was evaluated. A total of 1.15 +/- 0.22 aberrations were encountered in the exposed group as compared with 0.47 +/- 0.12 aberrations in the age matched controls. The increase in CAs in the exposed group was highly significant (P < 0.01, test of variance). A strongly positive correlation between increasing exposure duration and a higher incidence of CAs was apparent. No stratification for a higher incidence of CAs on the basis of smoking and/or alcoholic habits could be made in the exposed group.
Sobti
R C
RC
Department of Zoology, Panjab University, Chandigarh, India.
Bhardwaj
D K
DK
D000328:Adult; D000428:Alcohol Drinking; D002478:Cells, Cultured; D002842:Chromatids / Q000648:ultrastructure; D002869:Chromosome Aberrations; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000166:cytology* / Q000276:immunology; D016273:Occupational Exposure; D012016:Reference Values; D012907:Smoking; D013997:Time Factors; D001335:Vehicle Emissions / Q000633:toxicity
D001335:Vehicle Emissions