[Lymphadenopathy of dermatosis in the course of drug hypersensitivity. Cytologic, immunohisto- and immunocytologic, ultrastructural aspects. Report of a case].
In addition to the morphological details obtained from the imprints, a simple immunocytological study allowed us to diagnose one case of a dermopathic lymphadenopathy simulating a T cell lymphoma, following a drug-induced erythrodermia. We were able to identify the increase of CD1a+ and Prot. S100+ cells on acetone fixed imprints. The histological, immunohistological and ultrastructural investigations confirmed the value of the cytological study and that the dendritic cells were Langerhans cells (Birbeck granules+). Most of them were considered as migrating from the dermal lesions.
Brabencova
E
E
Service d'anatomie et de cytologie pathologiques, C.H. Victor Dupouy, Argenteuil.
Marais
M H
MH
Gaulier
A
A
Ploton
D
D
Adnet
J J
JJ
Marsan
C
C
D000293:Adolescent; D004342:Drug Hypersensitivity / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008206:Lymphatic Diseases / Q000209:etiology / Q000473:pathology*; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology*