title: How well does a three-sphere model predict positions of dipoles in a realistically shaped head?
abstract: The electrical potential produced by a dipole in the temporal or frontal lobe was calculated for a realistically shaped scalp, skull, and brain. This potential distribution was then used with a 3-sphere model to predict the position, orientation, and strength of the dipole source. The original and predicted dipole positions differed by an average of 1.97 cm, with a difference of more than 4 cm in some cases. Control calculations demonstrated that this difference was not caused by numerical artifacts in the computation, but instead was due to a true difference between the 3-sphere and realistically shaped head models.
authors.affiliation: Biomedical Engineering and Instrumentation Program, National Institutes of Health, Bethesda, MD 20892.
authors.forename: B J
authors.initials: BJ
authors.lastname: Roth
authors.forename: M
authors.initials: M
authors.lastname: Balish
authors.forename: A
authors.initials: A
authors.lastname: Gorbach
authors.forename: S
authors.initials: S
authors.lastname: Sato
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008959:Models, Neurological