[Corticosteroid-induced glaucoma following treatment of the periorbital region].
In this paper we report on three patients with open-angle glaucoma following use of corticosteroid ointment in the periorbital region. Case 1 used fluocinolone acetonide 0.025% for vitiligo vulgaris in the left periorbital region for 2 years. The intraocular pressure (IOP) was 35 mmHg in the left eye. Case 2 used methylprednisolone 0.5% for atopic dermatitis for 14 years. The IOP was 21 mmHg in the right eye and 50 mmHg in the left. Case 3 used betamethasone valerate 0.12% for atopic dermatitis for 2 years. The IOP was 68 mmHg in the right eye and 21 mmHg in the left. The left eye of case 2 and the right eye of case 3 showed glaucomatous optic disc atrophy and visual field defect, and trabeculectomy was performed. Because of the risk of glaucoma, it is strongly recommended that dermatologists advise patients to consult with ophthalmologists regarding application of corticosteroids to the periorbital region.
Katsushima
H
H
Department of Ophthalmology, Sapporo Medical University School of Medicine, Hokkaido, Japan.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D001623:Betamethasone / Q000009:adverse effects; D002648:Child; D005260:Female; D005446:Fluocinolone Acetonide / Q000009:adverse effects; D005902:Glaucoma, Open-Angle / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects; D009915:Orbit
D000305:Adrenal Cortex Hormones; D005446:Fluocinolone Acetonide; D001623:Betamethasone; D008775:Methylprednisolone