title: Surgery for seizure-related structural lesions of the brain with intraoperative acute recording(ECoG) and functional mapping.
abstract: Epilepsy surgery has been demonstrated to be an effective alternative treatment for intractable partial or localization related epilepsy. Primary intracranial neoplasms and other structural lesions of the brain are important etiological factors in patients with partial seizure disorders. A neuroimaging identified lesion in patients with seizures, not necessarily medically refractory, may also be an indication for surgery in selected patients. Twelve patients operated on under local or general anesthesia for resection surgery underwent intraoperative recording(electrocorticogram) and/or functional mapping by electrical stimulation or somatosensory evoked potentials-(SSEPs) for identification of the secondary epileptogenic area and/or functional area; 2 meningiomas, 5 astrocytomas, 1 gangliocytoma, 1 abscess, 1 small AVM, 1 cysticercosis and one gliosis by previous intracerebral hemorrhage with middle cerebral artery(MCA) aneurysm. Among these, additional corticectomy or anterior temporal lobectomy was performed in eleven patients. All the patients did well after surgery with good outcomes as seizure free in nine(75%) out of 12 patients with 11.9 months of follow-up period, without any neurological deficits. Intraoperative recording and functional mapping of adjacent areas of the structural lesions of the brain are useful in surgery and can guide the extent of further resection.
authors.affiliation: Department of Neurosurgery, Keimyung University School of Medicine, Taegu, Korea.
authors.forename: E I
authors.initials: EI
authors.lastname: Son
authors.forename: S D
authors.initials: SD
authors.lastname: Yi
authors.forename: S W
authors.initials: SW
authors.lastname: Lee
authors.forename: H C
authors.initials: HC
authors.lastname: Lee
authors.forename: M B
authors.initials: MB
authors.lastname: Yim
authors.forename: I H
authors.initials: IH
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000503:physiopathology / Q000601:surgery*; D004569:Electroencephalography; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000503:physiopathology / Q000601:surgery*