[Cystic fibrosis: gynecological and obstetrical aspects].
Survival in patients with cystic fibrosis has considerably improved over the last years. Young adults are particularly concerned. Fertility in these patients is greatly decreased, especially in men due to obstructive azoospermia. In women, intra-uterine insemination with her spouse's sperm can overcome anomalies in the cervical glair. Several pregnancies in patients with cystic fibrosis have been reported, especially in women with a mild form of the disease. Prematurity is frequent, about 35% as is perinatal mortality related to the mother's status. When lung involvement is severe leading to major obstruction and hypoxia, cor pulmonae and denutrition, pregnancy remains a contraindication. Care for pregnant women (when pregnancy is possible) should rely on a multidisciplinary team and include a rigorous nutritional and anti-infection support.
Hubert
D
D
Service de Pneumologie, Hôpital Cochin, Paris.
Lepercq
J
J
Arfi
J S
JS
Francoual
C
C
Dusser
D
D
D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005298:Fertility; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology / Q000628:therapy; D013997:Time Factors