title: The pattern of expression of a 13-kDa protein (CS-32 antigen) in the retina and its target nuclei in developing and mature rats.
abstract: A polyclonal antibody (designated CS-32) immunopurifies a 13-kDa protein from the superior colliculus (SC) of neonatal rat. There is a strikingly inverse temporal relationship in expression of the 13-kDa protein in the developing retina and its principal target nuclei, SC and the dorsal lateral geniculate nucleus. The 13-kDa is a cell-surface protein expressed exclusively by neurones and is clearly associated with synapses.
authors.affiliation: Department of Physiology, University of Sydney, N.S.W., Australia.
authors.forename: Z
authors.initials: Z
authors.lastname: Dreher
authors.forename: K A
authors.initials: KA
authors.lastname: Nichol
authors.forename: M
authors.initials: M
authors.lastname: Schulz
authors.forename: B
authors.initials: B
authors.lastname: Dreher
authors.forename: M R
authors.initials: MR
authors.lastname: Bennett
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000954:Antigens, Surface / Q000096:biosynthesis* / Q000235:genetics / Q000302:isolation & purification; D001923:Brain Chemistry; D011508:Chondroitin Sulfate Proteoglycans / Q000302:isolation & purification; D005136:Eye Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000302:isolation & purification; D005455:Fluorescent Antibody Technique; D018507:Gene Expression Regulation, Developmental; D005829:Geniculate Bodies / Q000254:growth & development / Q000378:metabolism*; D008565:Membrane Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000302:isolation & purification; D009419:Nerve Tissue Proteins / Q000096:biosynthesis* / Q000235:genetics / Q000302:isolation & purification; D009474:Neurons / Q000378:metabolism / Q000648:ultrastructure; D051381:Rats; D012160:Retina / Q000254:growth & development / Q000378:metabolism*; D013477:Superior Colliculi / Q000254:growth & development / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism
chemical_list: D000954:Antigens, Surface; D011508:Chondroitin Sulfate Proteoglycans; D005136:Eye Proteins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins