title: Ornithine decarboxylase (ODC) activity in the liver of individual medaka (Oryzias latipes) of both sexes.
abstract: Ornithine decarboxylase (ODC) activity has been determined in the liver of individual medaka (N = 48). The results indicate a mean ODC activity of 1.69 +/- 1.77 nmol 14CO2/hr/mg protein. The fish displayed a large interindividual variation of normal ODC activity with a range of 140fold. However, no sex differences were observed. The findings also indicate that the mean ODC activity in this fish model is approximately 100fold greater than observations in the published literature as well as in our laboratory for commonly employed rodent models.
authors.affiliation: School of Public Health, University of Massachusetts, Amherst 01003.
authors.forename: E J
authors.initials: EJ
authors.lastname: Calabrese
authors.forename: D A
authors.initials: DA
authors.lastname: Leonard
authors.forename: L A
authors.initials: LA
authors.lastname: Baldwin
authors.forename: P T
authors.initials: PT
authors.lastname: Kostecki
mesh_terms: D000818:Animals; D005260:Female; D008099:Liver / Q000201:enzymology*; D008297:Male; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D009990:Oryzias / Q000378:metabolism*
chemical_list: D009955:Ornithine Decarboxylase