title: [Recombinant antibodies in serologic diagnosis].
abstract: In this paper we discuss the value of a new methodology for the production of monoclonal antibodies by recombinant techniques. This approach is especially useful for human monoclonal antibodies due to instability of human antibody-producing cell lines. As an example, we present a recombinant human antibody to the hepatitis C virus (HCV) core protein.
authors.affiliation: DRK-Blutspendezentrale Ulm, Abteilung Transfusionsmedizin, Universität Ulm, BRD.
authors.forename: A
authors.initials: A
authors.lastname: Wölpl
authors.forename: M
authors.initials: M
authors.lastname: Cardoso
authors.forename: K
authors.initials: K
authors.lastname: Siemoneit
authors.forename: K
authors.initials: K
authors.lastname: Koerner
authors.forename: B
authors.initials: B
authors.lastname: Kubanek
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology; D001782:Blood Donors; D003001:Cloning, Molecular; D006526:Hepatitis C / Q000175:diagnosis*; D006801:Humans; D016133:Polymerase Chain Reaction; D012698:Serologic Tests / Q000379:methods*; D014758:Viral Core Proteins / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D014758:Viral Core Proteins; C069130:nucleocapsid protein, Hepatitis C virus