A new polymorphic restriction site at the human atrial natriuretic peptide (hANP) gene locus.
A unique two allele polymorphism for both HpaII and SmaI is described in the second intron of the human atrial natriuretic peptide gene. It should be a useful marker of this candidate gene in familial susceptibility to hypertension.
Ramasawmy
R
R
INSERM U120, Hôpital Robert Debré, Paris, France.
Kotea
N
N
Lu
C
C
Sayada
C
C
Baligadoo
S
S
Krishnamoorthy
R
R
D000483:Alleles; D009320:Atrial Natriuretic Factor / Q000235:genetics*; D001483:Base Sequence; D004277:DNA, Single-Stranded / Q000032:analysis; D015257:DNA-Cytosine Methylases; D019003:Deoxyribonuclease HpaII; D015252:Deoxyribonucleases, Type II Site-Specific; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
D004277:DNA, Single-Stranded; D009320:Atrial Natriuretic Factor; C079006:DNA modification methylase XcyI; D015257:DNA-Cytosine Methylases; D019003:Deoxyribonuclease HpaII; D015252:Deoxyribonucleases, Type II Site-Specific