Pectoralis major muscle free flap in rat model.
The rat pectoralis muscle can serve as a vascularized, innervated muscle flap model. The muscle, consisting of superficialis and profundus portions, is supplied by separate neurovascular systems. The vessels to pectoralis profundus (averaging 0.3 mm in diameter) can be taken in continuity with the axillary vessels (averaging 11 mm in diameter), which are used for transplantation. The profundus portion of muscle weighed an average of 1.8 g, and the average pedicle length was 0.9 cm. Nine of 11 transplanted muscles were viable, with intact circulation at 72 hours. An example of muscle transplantation for tissue defect coverage was attempted. The pectoralis profundus transplant was technically reliable, and the muscle bulk and contour could allow biochemical and functional studies.
Zhang
F
F
Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, CA 94305, USA.
Kao
S D
SD
Walker
R
R
Lineaweaver
W C
WC
D000009:Abdominal Muscles / Q000601:surgery; D000714:Anastomosis, Surgical; D000818:Animals; D001366:Axillary Artery / Q000502:physiology / Q000601:surgery; D001367:Axillary Vein / Q000502:physiology / Q000601:surgery; D004195:Disease Models, Animal; D005240:Feasibility Studies; D006085:Graft Survival; D008297:Male; D008406:Masseter Muscle / Q000601:surgery; D009929:Organ Size; D010369:Pectoralis Muscles / Q000098:blood supply / Q000294:innervation / Q000637:transplantation*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow / Q000502:physiology; D013524:Surgical Flaps / Q000379:methods; D013895:Thoracic Arteries / Q000502:physiology / Q000601:surgery; D013900:Thoracic Nerves / Q000502:physiology / Q000601:surgery