title: Perivascular microglia in the rat neural lobe engulf magnocellular secretory terminals during osmotic stimulation.
abstract: The response of microglia in the rat neural lobe to osmotic stimulation has been studied. Microglia were identified by immunoreactivity for the macrophage markers OX-42 and F4/80. The numerical density of microglia did not change significantly with osmotic stimulation but microglia in the perivascular space partially or completely enclosed significantly greater numbers of neurosecretory terminals in osmotically stimulated animals.
authors.affiliation: Department of Human Anatomy, University of Oxford, UK.
authors.forename: T H
authors.initials: TH
authors.lastname: Mander
authors.forename: J F
authors.initials: JF
authors.lastname: Morris
mesh_terms: D000818:Animals; D015415:Biomarkers; D003681:Dehydration / Q000139:chemically induced / Q000503:physiopathology*; D016130:Immunophenotyping; D008297:Male; D017628:Microglia / Q000473:pathology*; D009411:Nerve Endings / Q000473:pathology; D009997:Osmotic Pressure; D010587:Phagocytosis; D010904:Pituitary Gland, Posterior / Q000098:blood supply / Q000473:pathology*; D051381:Rats; D012965:Sodium Chloride / Q000633:toxicity
chemical_list: D015415:Biomarkers; D012965:Sodium Chloride