Treatment of ocular fungal infections with oral fluconazole.
OBJECTIVE
We treated five patients who had ocular fungal infections with oral fluconazole to determine its safety and effectiveness.


METHODS
We reviewed the case histories of the five patients. One patient had coccidioidomycosis and four had endogenous Candida endophthalmitis.


RESULTS
The intraocular fungal infection resolved in all patients.


CONCLUSIONS
Fluconazole appears to be a safe and effective antifungal agent that can be administered orally and may be a useful agent for treating some intraocular fungal infections.
Luttrull
J K
JK
Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles, USA.
Wan
W L
WL
Kubak
B M
BM
Smith
M D
MD
Oster
H A
HA
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002177:Candidiasis / Q000188:drug therapy*; D003047:Coccidioidomycosis / Q000188:drug therapy*; D004361:Drug Tolerance; D009877:Endophthalmitis / Q000188:drug therapy* / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000188:drug therapy*; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged
D015725:Fluconazole