Insights into possible skeletal muscle nicotinic acetylcholine receptor (AChR) changes in some congenital myasthenias from physiological studies, point mutations, and subunit substitutions of the AChR.
Kaminski
H J
HJ
Department of Neurology, Department of Veterans Affairs Medical Center, Cleveland, Ohio 44106.
Ruff
R L
RL
D000109:Acetylcholine / Q000502:physiology; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000737:chemistry / Q000502:physiology; D007700:Kinetics; D008969:Molecular Sequence Data; D009045:Motor Endplate / Q000502:physiology; D009135:Muscular Diseases / Q000151:congenital* / Q000235:genetics / Q000503:physiopathology; D009469:Neuromuscular Junction / Q000502:physiology; D017354:Point Mutation; D011978:Receptors, Nicotinic / Q000235:genetics* / Q000502:physiology; D009435:Synaptic Transmission
D007473:Ion Channels; D011978:Receptors, Nicotinic; D000109:Acetylcholine