[Quality of life analysis in patients treated for breast cancers].
OBJECTIVE
Evaluate the different quality of life parameters in treated breast cancer patients.


METHODS
Retrospective analysis from 1977 to 1987.


METHODS
Bichat, Lariboisière and Tenon Hospitals.


METHODS
239 operated patients, with or without irradiation following or before chemotherapy, with or without hormonotherapy. Patients were divided into 4 groups according to age. STUDY PARAMETERS: Essentially, gynaecologic consequences of treatments (flush, menstrual cycles, fertility, vaginal dryness, breast reconstruction), effect of tamoxifen on genital organs and osteopenia.


RESULTS
Tamoxifen acts as an oestrogen both on genital organs and bones.


CONCLUSIONS
The impact of substitutive hormone therapy on quality of life should be evaluated in randomized studies.
Zylberberg
B
B
Service de Gynécologie, Groupe Hospitalier Bichat-Claude-Bernard, Paris.
Dormont
D
D
Uzan
S
S
Ferrand
S
S
Antoine
J M
JM
Madelenat
P
P
Dutranoy
G
G
Ravina
J H
JH
Salat-Baroux
J
J
D000328:Adult; D000367:Age Factors; D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology; D001943:Breast Neoplasms / Q000503:physiopathology* / Q000523:psychology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005298:Fertility / Q000187:drug effects; D006801:Humans; D007989:Libido / Q000187:drug effects; D016462:Mammaplasty; D008597:Menstrual Cycle / Q000187:drug effects; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D013629:Tamoxifen / Q000494:pharmacology
D000970:Antineoplastic Agents; D013629:Tamoxifen