Mapping of rat bilirubin UDP-glucuronosyl-transferase gene (Ugt1a1) to chromosome region 9q35-->q36.
Bilirubin and phenol UDP-glucuronosyltransferases (UGTs) are located on the same chromosome and comprise the UGT1 gene complex. A 1,763-bp cDNA probe (UGT1*0) specific for rat liver bilirubin UGT was used to localize the UGT1 complex locus (Ugt1a1) to chromosome region 9q35-->q36 by fluorescence in situ hybridization. This assignment is the first report on the location of a gene of the rat UGT1 complex using high-resolution banded metaphase chromosomes.
Nagai
F
F
Kyoritsu College of Pharmacy, Tokyo, Japan.
Satoh
H
H
Mori
S
S
Sato
H
H
Koiwai
O
O
Homma
H
H
Matsui
M
M
D000818:Animals; D002478:Cells, Cultured; D002874:Chromosome Mapping; D014453:Glucuronosyltransferase / Q000235:genetics*; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D014453:Glucuronosyltransferase