title: Increased bone metabolism in a patient undergoing long-term rhG-CSF treatment for idiopathic acquired neutropenia.
abstract: Recombinant human granulocyte colony-stimulating factor (rhG-CSF) has been used mainly for treatment of chemotherapy-induced neutropenia. The reported side effects were of minor importance. We describe a case of long-term treatment with rhG-CSF, in which we observed enhanced bone remodeling.
authors.affiliation: Central Hematology Laboratory, University of Bern, Inselspital, Switzerland.
authors.forename: U J
authors.initials: UJ
authors.lastname: Woermann
authors.forename: R
authors.initials: R
authors.lastname: Schenk
authors.forename: A
authors.initials: A
authors.lastname: Zimmermann
authors.forename: A
authors.initials: A
authors.lastname: Tobler
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000378:metabolism*; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor