[Angiogenesis in the neoplastic process].
Solid tumor growth is accompanied by neovascularisation. In the absence of neovascularisation most tumors might become dormant at a tiny diameter 2-3 mm. New capillary growth is elicited by a diffusible factors generated by malignant tumor cells and by host cells. The inhibition of angiogenesis may provide a form of cancer treatment, either substitutional or additional to the conventional form of therapy. The present review summarized the state of our knowledge on this topic, angiogenesis and tumor growth.
Gil
M
M
Roszkowski
K
K
D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000098:blood supply* / Q000628:therapy; D009389:Neovascularization, Pathologic / Q000517:prevention & control*