Dopamine-producing paraganglioma not visualized by iodine-123-MIBG scintigraphy.
A patient with an aorticopulmonary paraganglioma was found to have normal plasma norepinephrine and epinephrine levels and elevated dopamine levels. Iodine-123-MIBG scintigraphy did not visualize this tumor. The same finding on a negative MIBG scan in two patients with exclusively dopamine-secreting chemodectomas has been previously reported. In our patient, [111In-DTPA-D-Phe1]-octreotide scintigraphy proved to be an effective imaging technique.
van Gelder
T
T
Department of Internal Medicine I, University Hospital Rotterdam, The Netherlands.
Verhoeven
G T
GT
de Jong
P
P
Oei
H Y
HY
Krenning
E P
EP
Vuzevski
V D
VD
van den Meiracker
A H
AH
D019797:3-Iodobenzylguanidine; D001016:Aortic Bodies / Q000000981:diagnostic imaging*; D003287:Contrast Media; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008875:Middle Aged; D010236:Paraganglioma, Extra-Adrenal / Q000000981:diagnostic imaging* / Q000378:metabolism*; D011877:Radionuclide Imaging; D013004:Somatostatin / Q000031:analogs & derivatives
D003287:Contrast Media; D007205:Indium Radioisotopes; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine; D013004:Somatostatin; C081788:pentetreotide; D004298:Dopamine