[Measures for infection in multiple myeloma].
A peculiarity of infection, as a complication of multiple myeloma in hematopoietic malignancies, is discussed. The Hanshin Study Group of Hematopoietic Disorders and Infection treated 3346 cases of bacterial infection during the past 13 years. Myeloma patients showed a low rate of 3.0% as compared with 28.2% of acute myelogenous leukemia patients. In patients with long term administration of antibiotics or bone marrow suppression, it is necessary to watch for fungus infection. Recently, new combination chemotherapy (DMVM-IFN alpha) is widely used in Japan. A high complete remission rate has been achieved by this regimen, but the incidence of infection tends to increase. Measures for infection in multiple myeloma should therefore be similar to that acute leukemia.
Horiuchi
A
A
Third Department of Internal Medicine, Kinki University School of Medicine.
Azuma
T
T
D001424:Bacterial Infections / Q000209:etiology*; D006801:Humans; D009101:Multiple Myeloma / Q000150:complications*; D009181:Mycoses / Q000209:etiology*