[Role of induction chemotherapy in advanced carcinoma of the larynx].
Results of comprehensive therapy for 43 cases of advanced carcinoma of the larynx are reported in this paper. Methods adopted were preoperative induction chemotherapy and surgical resection. The chemotherapy protocol was composed of Cis-Di-aminodichloroplatinum+Vincristine+Pingyangmycin and Pingyangmycin+Dexamethasone the 3- and 5-year survival rates of these patients were 62.8% and 54.2% respectively. In our opinion, induction chemotherapy can play a better role in raising the resection and survival rates for this kind of malignancy.
Yu
S G
SG
Henan Tumour Hospital, Zhengzhou.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D012074:Remission Induction; D015996:Survival Rate; D014750:Vincristine / Q000008:administration & dosage
D001761:Bleomycin; D014750:Vincristine; D003907:Dexamethasone; D002945:Cisplatin