title: [Early amniocentesis between the 12th-14th week of pregnancy. Clinical experiences with 1,100 cases].
abstract: Information is presented on 1100 early amniocenteses between the 12th and 14th week of gestation, performed at the Evangelisches Krankenhaus Oberhausen over a two year period. In all cases, a sufficient amount of amniotic fluid was obtained. In 99.7%, the cytogenetic diagnosis was successful. In 2.6% (29 patients), an aberrant karyotype was found. The time of cultivation was in the same range as can be observed in standard amniocentesis. The AFP-median measurements correlate with other studies. The spontaneous abortion rate was 0.3%. We conclude, that early amniocentesis can be performed safely and successfully by an experienced surgeon between the 12th to 14th week of gestation.
authors.affiliation: Institut für Klinische Genetik und Frauenklinik, Evangelisches Krankenhaus Oberhausen.
authors.forename: B
authors.initials: B
authors.lastname: Eiben
authors.forename: R
authors.initials: R
authors.lastname: Goebel
authors.forename: G
authors.initials: G
authors.lastname: Rutt
authors.forename: K D
authors.initials: KD
authors.lastname: Jaspers
authors.forename: S
authors.initials: S
authors.lastname: Hansen
authors.forename: W
authors.initials: W
authors.lastname: Hammans
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology; D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010865:Pilot Projects; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012307:Risk Factors; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins