title: Immunological relationship among rat erythrocyte membrane sialoglycoproteins and with human glycophorins.
abstract: 1. Specific antibodies against a whole preparation of glycophorins from rat erythrocyte membrane and against its most prominent component (32 kDa) were prepared. 2. Both antisera and the respective affinity-purified antibodies recognize the 74, 32 and 25 kDa components of rat glycophorins; therefore, a close antigenic relationship between them can be inferred. 3. On the other hand, a cross-reaction with human glycophorin A (both MM- and NN-type) is observed for both antisera. 4. This suggests the existence of epitopes common to human and rat glycophorins.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Universidad de Alcalá, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Herráez
authors.forename: A
authors.initials: A
authors.lastname: Díaz
authors.forename: J
authors.initials: J
authors.lastname: Luque
authors.forename: J C
authors.initials: JC
authors.lastname: Díez
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology; D002846:Chromatography, Affinity; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes / Q000276:immunology; D004910:Erythrocyte Membrane / Q000276:immunology*; D006021:Glycophorins / Q000276:immunology*; D006801:Humans; D008297:Male; D008856:Microscopy, Fluorescence; D051381:Rats; D017208:Rats, Wistar; D012795:Sialoglycoproteins / Q000276:immunology*
chemical_list: D000906:Antibodies; D000939:Epitopes; D006021:Glycophorins; D012795:Sialoglycoproteins