title: Slowly progressive aphasia associated with surface dyslexia.
abstract: We report an Italian patient affected by slowly progressive aphasia (SPA) lasting since four years when he first came to our observation. During the successive four years, we documented a progressive language decline resembling transcortical sensory aphasia, associated with a reading disorder corresponding to surface dyslexia, a form extremely rare in patients with native transparent language. His performance at standard intelligence tasks remained in the normal range, without any variation. CT scan showed left temporal atrophy. We emphasize the heterogeneity of the syndrome of SPA and suggest that it can represent one of the pictures of focal cortical degenerative disease, with variable onset, progression, and evolution.
authors.affiliation: II Clinica Neurologica, II Facoltà di Medicina, Napoli.
authors.forename: L
authors.initials: L
authors.lastname: Chiacchio
authors.forename: D
authors.initials: D
authors.lastname: Grossi
authors.forename: M
authors.initials: M
authors.lastname: Stanzione
authors.forename: L
authors.initials: L
authors.lastname: Trojano
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000368:Aged; D000849:Anomia / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D001037:Aphasia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D001041:Aphasia, Wernicke / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D001284:Atrophy; D004411:Dyslexia, Acquired / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010700:Phonetics; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014705:Verbal Behavior / Q000502:physiology