title: Reversal of gold-induced neutropenia with granulocyte colony-stimulating factor (G-CSF).
abstract: We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection. The patient suffered no side effects, and use of G-CSF represents an important addition to the management of a life-threatening drug reaction.
authors.affiliation: Department of Rheumatology, St George's Hospital, London.
authors.forename: D A
authors.initials: DA
authors.lastname: Collins
authors.forename: J H
authors.initials: JH
authors.lastname: Tobias
authors.forename: R P
authors.initials: RP
authors.lastname: Hill
authors.forename: B E
authors.initials: BE
authors.lastname: Bourke
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D006052:Gold Sodium Thiomalate / Q000009:adverse effects* / Q000627:therapeutic use; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D009503:Neutropenia / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D006052:Gold Sodium Thiomalate; D016179:Granulocyte Colony-Stimulating Factor