title: [Cytokines and solid tumors].
abstract: Various cytokines can be used in the treatment of solid tumours. They are factors of proliferation and/or differentiation of haematopoiesis or immunopoiesis, and they stimulate the effector cells of anti-tumoral response. The various steps in the preclinical and clinical development of a cytokine in the field of oncology are detailed, taking IL-2 as an example. The results of the clinical trials reported (essentially with INF and IL-2) are presented and discussed.
authors.affiliation: Service d'hémato-immunologie, INSERM U 333, Institut Gustave-Roussy, Villejuif.
authors.forename: F
authors.initials: F
authors.lastname: Triebel
authors.forename: B
authors.initials: B
authors.lastname: Escudier
mesh_terms: D016207:Cytokines / Q000145:classification / Q000627:therapeutic use*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D007376:Interleukin-2 / Q000627:therapeutic use; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D016207:Cytokines; D007376:Interleukin-2; D007372:Interferons