A promoter mutation of the beta-globin gene (-101 C-->T) has an age-related expression pattern.
Murru
S
S
Pischedda
M C
MC
Cao
A
A
Rosatelli
M C
MC
Pirastu
M
M
Sciarratta
G V
GV
Manca
L
L
Gallisai
D
D
Toffoli
C
C
D000328:Adult; D000375:Aging / Q000235:genetics*; D001483:Base Sequence; D003596:Cytosine; D005260:Female; D005319:Fetal Hemoglobin / Q000032:analysis; D005333:Fetus; D005786:Gene Expression Regulation; D005914:Globins / Q000235:genetics*; D006441:Hemoglobin A / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017354:Point Mutation; D011247:Pregnancy; D011401:Promoter Regions, Genetic; D013941:Thymine
D003596:Cytosine; D005914:Globins; D006441:Hemoglobin A; D005319:Fetal Hemoglobin; D013941:Thymine