title: Frequency of chromosomal aberrations after exposure to gamma-radiation of human chorionic villi.
abstract: We investigated the chromosomal damage induced by in vitro exposure to gamma-rays of uncultured first trimester chorionic villi. Frequency and types of chromosomal aberrations at increasing doses of radiation have been evaluated on cytotrophoblast spontaneous metaphases obtained after a short term incubation. Our results indicate a direct correlation between radiation dose and aberration frequency.
authors.affiliation: Centro Trasfusionale, Istituti Clinici di Perfezionamento, Milan, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Salvi
authors.forename: C
authors.initials: C
authors.lastname: De Andreis
authors.forename: S
authors.initials: S
authors.lastname: Pariani
authors.forename: S
authors.initials: S
authors.lastname: Orsini
authors.forename: M
authors.initials: M
authors.lastname: Piantanida
authors.forename: F
authors.initials: F
authors.lastname: Rossella
authors.forename: G
authors.initials: G
authors.lastname: Simoni
mesh_terms: D002824:Chorionic Villi / Q000528:radiation effects*; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D008677:Metaphase