title: Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation.
abstract: Cytogenetic studies were performed in lymphocytes from hospital workers exposed to low doses of radiation (1.6-42.71 mSv). When compared with controls, exposed workers showed a significant increase in structural chromosome-type aberrations, acentric fragments being the most frequent alteration. Our results suggest that acentric fragments are good indicators of exposure to very low doses of radiation, although no dose-effect correlation was observed. The incidence of numerical abnormalities (hyperdiploidy) was significantly increased.
authors.affiliation: Departament de Biologia Animal, Biologia Vegetal i Ecologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Bellaterra, Spain.
authors.forename: J F
authors.initials: JF
authors.lastname: Barquinero
authors.forename: L
authors.initials: L
authors.lastname: Barrios
authors.forename: M R
authors.initials: MR
authors.lastname: Caballín
authors.forename: R
authors.initials: R
authors.lastname: Miró
authors.forename: M
authors.initials: M
authors.lastname: Ribas
authors.forename: A
authors.initials: A
authors.lastname: Subias
authors.forename: J
authors.initials: J
authors.lastname: Egozcue
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D010564:Personnel, Hospital; D011839:Radiation, Ionizing