title: [Contemporary methods in the diagnosis and treatment of intrathoracic tuberculosis in children].
abstract: Reduced chemotherapy courses (6-10 months) were studied for effectivity in 108 children with advanced intrathoracic tuberculosis. Intramuscular isoniazid, pyrazinamide+rifampicin produced a complete response in 87.9% of the cases who suffered side effects 2 times less frequently. The overall treatment course became shorter by 2-3 months. The treatment of 157 children with destructive pulmonary tuberculosis required long-term (12 months and more) treatment with employment of all the tuberculostatic armory and surgical intervention in 15.3% of the cases.
authors.forename: L A
authors.initials: LA
authors.lastname: Mitinskaia
authors.forename: V F
authors.initials: VF
authors.lastname: Elufimova
authors.forename: N V
authors.initials: NV
authors.lastname: Iukhimenko
authors.forename: N P
authors.initials: NP
authors.lastname: Pogodaeva
authors.forename: K M
authors.initials: KM
authors.lastname: Iavorskiĭ
mesh_terms: D000284:Administration, Oral; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007273:Injections, Intramuscular; D007538:Isoniazid / Q000627:therapeutic use*; D011718:Pyrazinamide / Q000627:therapeutic use*; D012293:Rifampin / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin