title: Children of methadone-dependent women: developmental outcomes.
abstract: A group of 20 children was assessed for possible effects at school age of prenatal exposure to methadone. Compared to a control group of 20 nonexposed children on measures of cognitive, social, and emotional development, and of achievement, no significant differences were found on cognitive tests, although methadone exposure was associated with lower IQ scores. Methadone-exposed children exhibited greater anxiety, aggression, and rejection than did those in the control group, and their mothers reported more behavior problems.
authors.affiliation: School of Medicine, University of Miami, Fla.
authors.forename: M M
authors.initials: MM
authors.lastname: de Cubas
authors.forename: T
authors.initials: T
authors.lastname: Field
mesh_terms: D000342:Affective Symptoms / Q000139:chemically induced / Q000175:diagnosis / Q000523:psychology; D002648:Child; D002653:Child Behavior Disorders / Q000139:chemically induced / Q000175:diagnosis / Q000523:psychology; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D004522:Educational Status; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007360:Intelligence / Q000187:drug effects; D008297:Male; D008691:Methadone / Q000009:adverse effects*; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis / Q000523:psychology*; D011247:Pregnancy; D012307:Risk Factors; D012919:Social Behavior
chemical_list: D008691:Methadone