title: Antinociceptive properties and inhibition of neurogenic inflammation with potent SP antagonists belonging to perhydroisoindolones.
authors.affiliation: Rhone-Poulenc Rorer, Centre de Recherches de Vitry-Alfortville, Vitry-sur-Seine, France.
authors.forename: C
authors.initials: C
authors.lastname: Garret
authors.forename: A
authors.initials: A
authors.lastname: Carruette
authors.forename: V
authors.initials: V
authors.lastname: Fardin
authors.forename: S
authors.initials: S
authors.lastname: Moussaoui
authors.forename: F
authors.initials: F
authors.lastname: Montier
authors.forename: J F
authors.initials: JF
authors.lastname: Peyronel
authors.forename: P M
authors.initials: PM
authors.lastname: Laduron
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology*; D007249:Inflammation / Q000188:drug therapy / Q000503:physiopathology*; D054833:Isoindoles; D018041:Receptors, Neurokinin-2 / Q000187:drug effects / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013373:Substance P / Q000037:antagonists & inhibitors*; D015320:Tachykinins / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007211:Indoles; D054833:Isoindoles; D018041:Receptors, Neurokinin-2; D015320:Tachykinins; C071693:7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one; D013373:Substance P