title: Improved detection of a blood pressure response to dietary intervention with 24-hour ambulatory monitoring.
abstract: Ambulatory blood pressure (ABP) monitoring was undertaken in 25 hypertensives on beta-blocker monotherapy who completed a double-blind crossover trial to compare the effects of fish oil and corn oil supplements on BP. Clinic BP was measured with a Dinamap monitor on two consecutive days at the end of each treatment phase. ABP was recorded during the intervening 24-h period with a Spacelabs 90207 monitor. Averages of 24-h, daytime, and nighttime ABP readings correlated closely with Dinamap readings. Within-subject BP differences between fish oil and corn oil treatment were similar for Dinamap (3.2 +/- 1.8/2.5 +/- 1.0 mm Hg) and for 24-h ABP (2.5 +/- 1.0/2.3 +/- 0.8 mm Hg), but were more significant with the latter. Thus detection of the antihypertensive effects of dietary intervention can be improved by the use of ABP.
authors.affiliation: CSIRO Division of Human Nutrition, Adelaide, South Australia.
authors.forename: Y K
authors.initials: YK
authors.lastname: Lungershausen
authors.forename: P R
authors.initials: PR
authors.lastname: Howe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000187:drug effects*; D018660:Blood Pressure Monitoring, Ambulatory; D003314:Corn Oil / Q000627:therapeutic use*; D004311:Double-Blind Method; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000178:diet therapy / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged
chemical_list: D015525:Fatty Acids, Omega-3; D003314:Corn Oil