Brequinar sodium effectively and potently suppresses allograft rejection in a heterotopic mouse heart transplant model.
Murphy
M P
MP
Department of Thoracic Surgery, Stanford University School of Medicine, CA 94305-5247.
Morris
R E
RE
D000818:Animals; D001713:Biphenyl Compounds / Q000627:therapeutic use*; D016572:Cyclosporine / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006084:Graft Rejection / Q000517:prevention & control*; D016027:Heart Transplantation; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008954:Models, Biological; D011090:Polyenes / Q000627:therapeutic use; D020123:Sirolimus; D016559:Tacrolimus / Q000627:therapeutic use; D014184:Transplantation, Homologous; D011798:Quinaldines
D001713:Biphenyl Compounds; D016572:Cyclosporine; D007166:Immunosuppressive Agents; D011090:Polyenes; D020123:Sirolimus; D016559:Tacrolimus; C046943:brequinar; D011798:Quinaldines