title: [The use of prostaglandin E1 for emergency cesarean section in a patient with HELLP syndrome].
abstract: A 23-year-old female, gravida 0 para 0, underwent emergency cesarean section under general anesthesia, because of the complication of HELLP syndrome. Prostaglandin E1 (PGE1) was used to prevent hypertension and uterine atony just after the infant's delivery. The disorder was improved with the postpartum care. HELLP is the syndrome of hemolysis, elevated enzyme, and low platelets presented by a unique group of pre-eclamptic/eclamptic patients with or without the usual clinical findings of pregnancy-induced hypertension. PGE1 may be useful for microangiopathic hemolytic anemia, which might be related with the hemolysis, because of its inhibitory effect on both platelet aggregation and thrombus formation, and its ability to improve red cell deformability.
authors.affiliation: Department of Anesthesiology, St. Marianna University School of Medicine, Kawasaki.
authors.forename: H
authors.initials: H
authors.lastname: Hino
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D000527:Alprostadil / Q000627:therapeutic use*; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D004630:Emergencies; D005260:Female; D017359:HELLP Syndrome / Q000150:complications*; D006801:Humans; D011247:Pregnancy
chemical_list: D000527:Alprostadil