[Interactions in the system of copper ion-azalide (azithromycin)].
Interactions in the bio-inorganic systems of the copper ions and azalide (azithromycin) were analyzed by spectroscopic methods (atom-absorption spectroscopy, IR and UV spectrometry in the visible spectrum) and electrochemical methods (potentiometry). The system samples within molar ratios of the metal ion and ligand of 10:1 to 1:10 and wide pH ranges were tested. Formation of a compound consisting of the metal ion and ligand at a ratio of 1:1 was detected. The experimental data showed that the product of the compound solubility equaled 9.8.10(-14) (pH 7.0, 0.1 KNO3).
Sher
A A
AA
Ianovskaia
I M
IM
Malofeeva
L S
LS
D017963:Azithromycin / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D011199:Potentiometry; D012995:Solubility; D013053:Spectrophotometry
D003300:Copper; D017963:Azithromycin