Statistical mechanics of membrane channels.
Voltage-sensitive membrane channels show co-operative behaviour as evident from electrophysiological experiments. A statistical mechanical approach is suggested for a microscopic analysis of the system. A model of the Zimm-Bragg type is developed for a membrane with a large number of channels behaving co-operatively. The model is tested with voltage-dependent conductance data for gap-junction channels in embryonic cells.
Ghosh
S
S
Department of Biophysics, New Delhi, India.
Mukherjee
A
A
D004594:Electrophysiology; D006801:Humans; D007365:Intercellular Junctions / Q000502:physiology; D007473:Ion Channels / Q000502:physiology*; D008954:Models, Biological; D013223:Statistics as Topic
D007473:Ion Channels