title: [Quality of life analysis in patients treated for breast cancers].
abstract: OBJECTIVE
  Evaluate the different quality of life parameters in treated breast cancer patients.
  
  
  METHODS
  Retrospective analysis from 1977 to 1987.
  
  
  METHODS
  Bichat, Lariboisière and Tenon Hospitals.
  
  
  METHODS
  239 operated patients, with or without irradiation following or before chemotherapy, with or without hormonotherapy. Patients were divided into 4 groups according to age. STUDY PARAMETERS: Essentially, gynaecologic consequences of treatments (flush, menstrual cycles, fertility, vaginal dryness, breast reconstruction), effect of tamoxifen on genital organs and osteopenia.
  
  
  RESULTS
  Tamoxifen acts as an oestrogen both on genital organs and bones.
  
  
  CONCLUSIONS
  The impact of substitutive hormone therapy on quality of life should be evaluated in randomized studies.
authors.affiliation: Service de Gynécologie, Groupe Hospitalier Bichat-Claude-Bernard, Paris.
authors.forename: B
authors.initials: B
authors.lastname: Zylberberg
authors.forename: D
authors.initials: D
authors.lastname: Dormont
authors.forename: S
authors.initials: S
authors.lastname: Uzan
authors.forename: S
authors.initials: S
authors.lastname: Ferrand
authors.forename: J M
authors.initials: JM
authors.lastname: Antoine
authors.forename: P
authors.initials: P
authors.lastname: Madelenat
authors.forename: G
authors.initials: G
authors.lastname: Dutranoy
authors.forename: J H
authors.initials: JH
authors.lastname: Ravina
authors.forename: J
authors.initials: J
authors.lastname: Salat-Baroux
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology; D001943:Breast Neoplasms / Q000503:physiopathology* / Q000523:psychology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005298:Fertility / Q000187:drug effects; D006801:Humans; D007989:Libido / Q000187:drug effects; D016462:Mammaplasty; D008597:Menstrual Cycle / Q000187:drug effects; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D013629:Tamoxifen / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D013629:Tamoxifen