title: Portal vein thrombosis caused by protein C and protein S deficiency associated with cytomegalovirus infection.
abstract: A 4-month-old girl who was examined because of splenomegaly had portal vein thrombosis, which apparently resulted from a combination of cytomegalovirus infection and deficiency of both protein S and protein C. The cytomegalovirus infection, by damaging endothelial cells, may have triggered a cascade of events that was ultimately expressed as portal vein thrombosis resulting from deficiency of proteins S and C.
authors.affiliation: Department of Pediatrics, Dana Children's Hospital, Tel Aviv Medical Center, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Arav-Boger
authors.forename: S
authors.initials: S
authors.lastname: Reif
authors.forename: Y
authors.initials: Y
authors.lastname: Bujanover
mesh_terms: D001796:Blood Protein Disorders / Q000150:complications*; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D011169:Portal Vein; D020151:Protein C Deficiency; D018455:Protein S Deficiency / Q000150:complications*; D013927:Thrombosis / Q000209:etiology*