title: [Transformations of glycyrrhizic acid. VIII. Synthesis of immunomodulating glycopeptides using tert-butyl amino acid esters].
abstract: Triterpene glycopeptides, derivatives of glycyrrhizic acid, were synthesized with the use of tert-butyl esters of L-amino acids. The condensation of glycoside with esters was carried out with N-hydroxysuccinimide--N,N-dicyclohexylcarbodiimide or N-hydroxybenzotriazol--N,N'-dicyclohexylcarbodiimide in the presence of a base (triethylamine, N-methyl- or N-ethylmorpholine). The protection groups were removed with the use of trifluoroacetic acid.
authors.forename: L A
authors.initials: LA
authors.lastname: Baltina
authors.forename: S A
authors.initials: SA
authors.lastname: Ryzhova
authors.forename: E V
authors.initials: EV
authors.lastname: Vasil'eva
authors.forename: G A
authors.initials: GA
authors.lastname: Tolstikov
authors.forename: G M
authors.initials: GM
authors.lastname: Sakhautdinova
authors.forename: F S
authors.initials: FS
authors.lastname: Zarudiĭ
mesh_terms: D000276:Adjuvants, Immunologic / Q000138:chemical synthesis*; D000596:Amino Acids / Q000737:chemistry*; D000818:Animals; D002240:Carbohydrate Sequence; D004952:Esters; D006020:Glycopeptides / Q000138:chemical synthesis*; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D019695:Glycyrrhizic Acid; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008969:Molecular Sequence Data; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000276:Adjuvants, Immunologic; D000596:Amino Acids; D004952:Esters; D006020:Glycopeptides; D019695:Glycyrrhizic Acid; D006034:Glycyrrhetinic Acid