title: Specificity of the immunohistochemical demonstration of mycobacterial antigens.
abstract: The specificity of immunohistological reactions of commercial polyclonal antibodies to antigens of various mycobacteria (Mycobacterium bovis, Mycobacterium duvalii and Mycobacterium paratuberculosis) was tested in connection with a number of pathogens and with the help of the indirect immunoperoxidase technique. Positive reactions occurred with various mycobacterial antigens and some Gram-positive bacteria and fungi. These investigations indicate that when the above antibodies are used in histopathological diagnostics, false-positive results can be expected.
authors.affiliation: Institut für Tierpathologie, Universität München, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Geisel
authors.forename: F
authors.initials: F
authors.lastname: Netter
authors.forename: W
authors.initials: W
authors.lastname: Hermanns
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology; D000942:Antigens, Bacterial / Q000032:analysis*; D003429:Cross Reactions; D005189:False Positive Reactions; D006041:Goats; D006736:Horses; D007150:Immunohistochemistry; D009161:Mycobacterium / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial