IgA nephropathy and hypercalcemia in Whipple's disease.
In 2 patients an IgA nephropathy was found 2 and 5 years before gastrointestinal symptoms led to the diagnosis of Whipple's disease. One patient additionally presented with hypercalcemia. Subsequently 1 patient died, whereas treatment with trimethoprim/sulfamethoxazole resulted in an improvement of IgA nephropathy and in a complete recovery from hypercalcemia and all the manifestations of Whipple's disease in the other patient. IgA nephropathy and hypercalcemia may be considered as early manifestations of Whipple's disease.
Stoll
T
T
Department of Rheumatology, Clinic Wilhelm Schulthess, Zurich, Switzerland.
Keusch
G
G
Jost
R
R
Burger
H
H
Oelz
O
O
D000328:Adult; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006934:Hypercalcemia / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D008061:Whipple Disease / Q000150:complications* / Q000175:diagnosis