The importance of substrate concentration in determining cytochromes P450 therapeutically relevant in vivo.
Kato
R
R
Department of Pharmacology, School of Medicine, Keio University, Tokyo, Japan.
Yamazoe
Y
Y
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003975:Diazepam / Q000378:metabolism; D006801:Humans; D007099:Imipramine / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008617:Mephenytoin / Q000378:metabolism; D013379:Substrate Specificity
D003577:Cytochrome P-450 Enzyme System; D007099:Imipramine; D003975:Diazepam; D008617:Mephenytoin