title: [A case of pulmonary infiltrates associated with a neutrophil-specific antibody transfusion reactions].
abstract: A normovolemic pulmonary edema associated with blood transfusion developed in a 38-year-old woman during gynecological operation. Bilateral pulmonary infiltrates and profound leucopenia (700.microliters-1) were observed. An antibody reactive with the recipient's neutrophils was found in a donor and an antibody reacting with the lymphocytes of the recipient was identified in another donor. Both donors were multiparous women. Respiratory failure was improved with mechanical ventilation but chest X-ray showed pulmonary infiltrates for the next 3 days. The white blood cell count rose to 2900.microliters-1 in the next day, and it took 2 weeks to be normalized. Transient pulmonary infiltrates can be caused by antileukocyte antibodies passively transfused by multiparous donors.
authors.affiliation: Department of Anesthesiology, Fukushima Medical College.
authors.forename: K
authors.initials: K
authors.lastname: Kan
authors.forename: C
authors.initials: C
authors.lastname: Tase
authors.forename: H
authors.initials: H
authors.lastname: Ohto
authors.forename: T
authors.initials: T
authors.lastname: Isosu
authors.forename: K
authors.initials: K
authors.lastname: Niitsu
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D000918:Antibody Specificity; D005260:Female; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies; D007970:Leukopenia / Q000209:etiology*; D009504:Neutrophils / Q000276:immunology*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000601:surgery; D011654:Pulmonary Edema / Q000209:etiology*; D065227:Transfusion Reaction
chemical_list: D006680:HLA Antigens; D007518:Isoantibodies