title: Sudden onset of adverse effects due to low-dosage bleomycin indicates an idiosyncratic reaction.
abstract: We report a case of possible idiosyncratic reaction in a fifty-two-year-old man with centroblastic malignant lymphoma. Immediately after administration of 20 mg bleomycin intravenously for the first time, the patient developed stomatitis. When readministered a few weeks later the patient developed mucocutaneous manifestations such as stomatitis, symmetrical linear maculopapular exanthema on the neck, trunk, and both arms, and indurated nodules on the palms.
authors.affiliation: Department of Pathology, Gentofte University Hospital, Hellerup, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Haerslev
authors.forename: C
authors.initials: C
authors.lastname: Avnstorp
authors.forename: M
authors.initials: M
authors.lastname: Joergensen
mesh_terms: D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000473:pathology; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013280:Stomatitis / Q000139:chemically induced*
chemical_list: D001761:Bleomycin