title: Voltage-clamp and single channel analysis of Pb(2+)-induced current in isolated snail neurons.
abstract: Pb-activated outward current was investigated in intracellularly perfused, isolated snail neurons. Pb-ions induced non-inactivating but reversible current (IPb). The IPb showed concentration dependence. The I-V curve was linear with negative slope and the IPb proved to be Na-dependent.
authors.affiliation: Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.
authors.forename: J
authors.initials: J
authors.lastname: Gyóri
authors.forename: O N
authors.initials: ON
authors.lastname: Osipenko
authors.forename: T
authors.initials: T
authors.lastname: Kiss
mesh_terms: D000818:Animals; D005071:Evoked Potentials / Q000187:drug effects; D006372:Helix, Snails; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology*; D007854:Lead / Q000494:pharmacology*; D008564:Membrane Potentials; D009474:Neurons / Q000187:drug effects / Q000502:physiology*
chemical_list: D007473:Ion Channels; D007854:Lead