title: Actuarial survival of transvenous pacing leads in a pediatric population.
abstract: This study was undertaken to examine the actuarial survival of endocardial pacing leads in a pediatric population. We prospectively followed 148 children and young adults age 4 months to 38 years. Of these, 58 had normal cardiac anatomy and 90 had surgically corrected congenital heart disease. A total of 213 leads were inserted in these patients. Actuarial analysis showed that at 5 years 76.0% of the pacemaker leads were still in use. The reasons for abandonment included death (10), exit block (8), lead fracture (8), adapter malfunction (7), and other including infection, lead migration, and pacemaker malfunction (12). Excluding deaths, an actuarial survival curve was constructed. Stepwise discriminant analysis and independent measures of association showed a significant difference in lead abandonment when the leads placed in the atrium were compared to those placed in the ventricle (30 vs 5; P < 0.0005). Lead insulating material, cardiac anatomy, and/or indication for pacemaker placement had no statistically significant impact on lead survival.
authors.affiliation: Medical University of South Carolina, South Carolina Children's Heart Center, Charleston 29425.
authors.forename: Y R
authors.initials: YR
authors.lastname: Lau
authors.forename: P C
authors.initials: PC
authors.lastname: Gillette
authors.forename: D S
authors.initials: DS
authors.lastname: Buckles
authors.forename: V L
authors.initials: VL
authors.lastname: Zeigler
mesh_terms: D000206:Actuarial Analysis; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004868:Equipment Failure; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D010138:Pacemaker, Artificial / Q000009:adverse effects; D011446:Prospective Studies