Cleavage of yeast tRNA(phe) with Ni(III) and Co(III) complexes of bleomycin.
The BLM-Ni(III) complex preferentially cleaves guanine residues at D loop and anticodon loop of yeast tRNA(phe) by aniline treatment, whereas the BLM-Co(III) complex degrades certain 5'-AN sites of the minor groove region after irradiation of UV light. These cleavage features are clearly different from that of the BLM-Fe(II) complex.
Guan
L L
LL
Institute for Chemical Research, Kyoto University, Japan.
Totsuka
R
R
Kuwahara
J
J
Otsuka
M
M
Sugiura
Y
Y
D001483:Base Sequence; D001761:Bleomycin / Q000737:chemistry*; D003035:Cobalt / Q000737:chemistry; D006860:Hydrogen Bonding; D006868:Hydrolysis; D066298:In Vitro Techniques; D008969:Molecular Sequence Data; D009532:Nickel / Q000737:chemistry; D012331:RNA, Fungal / Q000737:chemistry; D012360:RNA, Transfer, Phe / Q000737:chemistry* / Q000648:ultrastructure; D012441:Saccharomyces cerevisiae
D012331:RNA, Fungal; D012360:RNA, Transfer, Phe; D001761:Bleomycin; D003035:Cobalt; D009532:Nickel