title: Diagnosis and treatment of fetal anemia due to isoimmunization.
abstract: 45 pregnant women affected by rhesus incompatibility were treated at the Department of Prenatal Diagnosis and Therapy, Vienna, between January 1992 and March 1993. 32 patients had a cordocentesis and on 21 fetuses, anemia requiring treatment was diagnosed. A total of 71 intravascular transfusions via the umbilical vein was given. The mean number of transfusions per fetus was 3.4 (range 1-11). Of the 7 fetuses who had already developed hydrops when therapy was started (hematocrit < 13%), 5 (71%) survived. The survival rate of non-hydropic anemic fetuses was 93% (13/14). By using intravascular transfusion for treatment of severe fetal anemia, a success rate of 86% (18/21) was achieved.
authors.affiliation: Department of Prenatal Diagnosis and Therapy, University of Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Plöckinger
authors.forename: I
authors.initials: I
authors.lastname: Strümpflen
authors.forename: J
authors.initials: J
authors.lastname: Deutinger
authors.forename: G
authors.initials: G
authors.lastname: Bernaschek
mesh_terms: D001805:Blood Transfusion, Intrauterine; D017218:Cordocentesis; D004899:Erythroblastosis, Fetal / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012189:Retrospective Studies; D012203:Rh Isoimmunization / Q000150:complications*; D016896:Treatment Outcome