Extracellular recording in neuronal networks with substrate integrated microelectrode arrays.
A photolithographically produced array of 60 substrate-integrated microelectrodes was used for extracellular recording. Neuronal electrical activity was recorded from chicken retinal ganglion cells with or without stimulation by diffuse light. The retina was removed from chicken embryos of embryonic day 14-18. Only cells recorded from day 18 retina would react to photostimulation, increasing their activity when stimulated, corresponding to the developmental time course of photoreceptor differentiation.
Hämmerle
H
H
Naturwissenschaftliches und Medizinisches Institut, Universität Tübingen in Reutlingen, Germany.
Egert
U
U
Mohr
A
A
Nisch
W
W
D000818:Animals; D002642:Chick Embryo; D008839:Microelectrodes; D009415:Nerve Net / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology*