Portal vein thrombosis caused by protein C and protein S deficiency associated with cytomegalovirus infection.
A 4-month-old girl who was examined because of splenomegaly had portal vein thrombosis, which apparently resulted from a combination of cytomegalovirus infection and deficiency of both protein S and protein C. The cytomegalovirus infection, by damaging endothelial cells, may have triggered a cascade of events that was ultimately expressed as portal vein thrombosis resulting from deficiency of proteins S and C.
Arav-Boger
R
R
Department of Pediatrics, Dana Children's Hospital, Tel Aviv Medical Center, Israel.
Reif
S
S
Bujanover
Y
Y
D001796:Blood Protein Disorders / Q000150:complications*; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D011169:Portal Vein; D020151:Protein C Deficiency; D018455:Protein S Deficiency / Q000150:complications*; D013927:Thrombosis / Q000209:etiology*