Treatment of prostatic bleeding: suppression of angiogenesis by androgen deprivation.
Bleeding of prostatic origin is usually caused by the friable hypervascularity of the aging prostate. Suppression of angiogenesis can be achieved through any hormonal manipulation that causes androgen deprivation. We present 4 cases of severe recurrent hematuria treated successfully by this approach.
Marshall
S
S
Department of Urology, University of California School of Medicine, San Francisco.
Narayan
P
P
D000368:Aged; D000369:Aged, 80 and over; D004054:Diethylstilbestrol / Q000627:therapeutic use*; D004966:Estrogens, Conjugated (USP) / Q000627:therapeutic use*; D005485:Flutamide / Q000627:therapeutic use*; D006417:Hematuria / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000150:complications / Q000517:prevention & control*; D011467:Prostate / Q000098:blood supply*; D011470:Prostatic Hyperplasia / Q000150:complications; D011471:Prostatic Neoplasms / Q000150:complications
D004966:Estrogens, Conjugated (USP); D004054:Diethylstilbestrol; D005485:Flutamide