title: P3-like potential in rats.
abstract: Auditory event-related potentials (ERPs) were recorded from the skull surface in unrestrained, unanesthetized rats. Infrequent deviant tones presented randomly within a sequence of repetitive tones enhanced a long-latency positive component peaking at 240 msec. This rodent ERP was comparable to the human P3a component in latency and sensitivity to stimulus probability. The rodent may provide a useful model for investigation of the neural sources of the P3.
authors.affiliation: Department of Neurology, University of California, Davis.
authors.forename: S
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: H
authors.initials: H
authors.lastname: Globus
authors.forename: R T
authors.initials: RT
authors.lastname: Knight
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D004195:Disease Models, Animal; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology; D008297:Male; D011336:Probability; D051381:Rats; D011916:Rats, Inbred F344; D011930:Reaction Time; D012815:Signal Processing, Computer-Assisted; D014793:Visual Cortex / Q000502:physiology