title: High frequency gene targeting using insertional vectors.
authors.affiliation: MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
authors.forename: P
authors.initials: P
authors.lastname: Dickinson
authors.forename: W L
authors.initials: WL
authors.lastname: Kimber
authors.forename: F M
authors.initials: FM
authors.lastname: Kilanowski
authors.forename: B J
authors.initials: BJ
authors.lastname: Stevenson
authors.forename: D J
authors.initials: DJ
authors.lastname: Porteous
authors.forename: J R
authors.initials: JR
authors.lastname: Dorin
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D018118:Chloride Channels / Q000235:genetics; D003550:Cystic Fibrosis / Q000235:genetics*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D004247:DNA / Q000032:analysis; D017931:DNA Primers; D004195:Disease Models, Animal; D004622:Embryo, Mammalian; D005822:Genetic Vectors; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D008565:Membrane Proteins / Q000235:genetics*; D051379:Mice; D016254:Mutagenesis, Insertional; D016133:Polymerase Chain Reaction; D011995:Recombination, Genetic; D015183:Restriction Mapping; D013234:Stem Cells; D013937:Thymidine Kinase / Q000235:genetics
chemical_list: D018118:Chloride Channels; D017931:DNA Primers; D008565:Membrane Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D004247:DNA; D007041:Hypoxanthine Phosphoribosyltransferase; D013937:Thymidine Kinase