Voltage-clamp and single channel analysis of Pb(2+)-induced current in isolated snail neurons.
Pb-activated outward current was investigated in intracellularly perfused, isolated snail neurons. Pb-ions induced non-inactivating but reversible current (IPb). The IPb showed concentration dependence. The I-V curve was linear with negative slope and the IPb proved to be Na-dependent.
Gyóri
J
J
Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.
Osipenko
O N
ON
Kiss
T
T
D000818:Animals; D005071:Evoked Potentials / Q000187:drug effects; D006372:Helix, Snails; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology*; D007854:Lead / Q000494:pharmacology*; D008564:Membrane Potentials; D009474:Neurons / Q000187:drug effects / Q000502:physiology*
D007473:Ion Channels; D007854:Lead