Cutaneous giant cell hyalin angiopathy.
Giant cell hyalin angiopathy (GCHA) is an unusual histologic finding associated with inflammation. The lesion has previously only been reported intraorally and is usually preceded by trauma. We report the first case of cutaneous GCHA. The eosinophilic, amorphous material (so-called "hyalin") stained for light chain products, suggesting that their deposition resulted from a reactive process associated with inflammation.
Martin
R W
RW
Department of Dermatology, Johns Hopkins University School of Medicine Baltimore, Maryland.
Lumadue
J A
JA
Corio
R L
RL
Kalb
R L
RL
Hood
A F
AF
D000328:Adult; D015726:Giant Cells / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D008297:Male; D010522:Periostitis / Q000473:pathology; D012867:Skin / Q000378:metabolism / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D014657:Vasculitis / Q000378:metabolism / Q000473:pathology*