The value of radiotherapy or chemotherapy after intubation for advanced esophageal carcinoma--a prospective randomized trial.
After intubation for advanced, inoperable squamous carcinoma of the oesophagus, a prospectively controlled randomized trial was done to investigate the effect of radiotherapy (41 patients) or mono-chemotherapy (40 patients) or no further treatment (46 patients). Treatment had no significant effect on either palliation or survival (p < or = 0.7) and did not alter the natural history of the disease.
Schmid
E U
EU
Department of Surgery, Verwoerd Hospital, University of Pretoria, South Africa.
Alberts
A S
AS
Greeff
F
F
Terblanche
A P
AP
Schoeman
L
L
Burger
W
W
Shiels
R A
RA
Friediger
D
D
Van der Hoven
A
A
Falkson
G
G
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D004947:Esophagus; D005260:Female; D006801:Humans; D007440:Intubation; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011446:Prospective Studies; D015996:Survival Rate