title: Cytotoxic T lymphocyte epitopes shared between HIV-1, HIV-2, and SIV.
abstract: A peptide epitope from the gag protein of SIV and from HIV-1 is described which is presented by a cynomolgus macaque MHC molecule and with HLA B14. Comparisons were drawn between recognition of this peptide and that of a second peptide defined in SIV and HIV-2 which has been reported to be presented by the rhesus macaque molecule MaMuA01 and HLA B53 respectively.
authors.affiliation: Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, U.K.
authors.forename: F
authors.initials: F
authors.lastname: Gotch
authors.forename: D
authors.initials: D
authors.lastname: Nixon
authors.forename: A
authors.initials: A
authors.lastname: Gallimore
authors.forename: S
authors.initials: S
authors.lastname: McAdam
authors.forename: A
authors.initials: A
authors.lastname: McMichael
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017951:Antigen Presentation; D000956:Antigens, Viral / Q000235:genetics; D000939:Epitopes / Q000235:genetics; D015683:Gene Products, gag / Q000235:genetics / Q000276:immunology; D015658:HIV Infections / Q000276:immunology; D015497:HIV-1 / Q000235:genetics / Q000276:immunology*; D015498:HIV-2 / Q000235:genetics / Q000276:immunology*; D015235:HLA-B Antigens; D059909:HLA-B14 Antigen; D006649:Histocompatibility Antigens; D006801:Humans; D066298:In Vitro Techniques; D008252:Macaca fascicularis; D008297:Male; D008969:Molecular Sequence Data; D015302:Simian Immunodeficiency Virus / Q000235:genetics / Q000276:immunology*; D013045:Species Specificity; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014611:Vaccination
chemical_list: D000956:Antigens, Viral; D000939:Epitopes; D015683:Gene Products, gag; D015235:HLA-B Antigens; D059909:HLA-B14 Antigen; D006649:Histocompatibility Antigens