title: The role of the O-antigen lipopolysaccharide on the colonization in vivo of the germfree chicken gut by Klebsiella pneumoniae.
abstract: We isolated lipopolysaccharide and capsular polysaccharide (K antigen)-defective mutants from two Klebsiella pneumoniae parental strains, and compared their ability to colonize in vivo the germfree chicken gut. The high-molecular weight lipopolysaccharide (LPS) (O antigen) was found necessary for the colonization while the capsular polysaccharide (K2 or K29) was not of importance.
authors.affiliation: Departamento de Microbiologïa, Universidad de Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Camprubí
authors.forename: S
authors.initials: S
authors.lastname: Merino
authors.forename: J F
authors.initials: JF
authors.lastname: Guillot
authors.forename: J M
authors.initials: JM
authors.lastname: Tomás
mesh_terms: D000818:Animals; D016667:Bacterial Capsules / Q000032:analysis / Q000502:physiology*; D002645:Chickens / Q000382:microbiology*; D004064:Digestive System / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005856:Germ-Free Life; D007711:Klebsiella pneumoniae / Q000737:chemistry* / Q000472:pathogenicity; D008070:Lipopolysaccharides / Q000032:analysis; D009154:Mutation; D019081:O Antigens; D011135:Polysaccharides, Bacterial / Q000032:analysis / Q000502:physiology*
chemical_list: D008070:Lipopolysaccharides; D019081:O Antigens; D011135:Polysaccharides, Bacterial