title: [Results of conservative surgery in T1 breast carcinoma. Our experience in 66 treated cases].
abstract: Between 1989 and 1991, 66 women affected by breast cancer smaller than 2 cm in diameter, were treated with conservative procedure plus radiotherapy. Conservative procedure consisted in quadrantectomy and axillary dissection of the 3 axillary nodes levels. Neoplasms were grouped according to TNM classification. Eleven were classified as Tis, 9 as T1aN0M0, 12 as T1bN0M0, one case T1bN1M0, 24 as T1cN0M0 and finally 9 as T1cN1M0. Actuarial 5-year survival rate was related to TNM. It has been reported to be 100% in Tis and T1aN0M0 neoplasms; 91.7% in pT1bN0M0 tumors, 95.8% in pT1cN0M0 neoplasms, 55.6% in patients affected with pT1cN1M0 tumors. According to the relationship between receptor status of the neoplasm and survival, this was 88.9% in ER+ and 77.8% in ER- tumors, and 97.1% against 71.4% (p < 0.05) in PR+ and PR- neoplasms respectively. Two patients presented (3%) local recurrence which were treated by means of a tumorectomy and radiotherapy. Both patients are still living and disease free after 6 and 9 months from re-operation.
authors.affiliation: I Clinica Chirurgica, Università degli Studi di Roma La Sapienza, Roma.
authors.forename: P
authors.initials: P
authors.lastname: Barillari
authors.forename: R
authors.initials: R
authors.lastname: Leuzzi
authors.forename: M
authors.initials: M
authors.lastname: Nardi
authors.forename: A
authors.initials: A
authors.lastname: Cerasi
authors.forename: D
authors.initials: D
authors.lastname: Calcaterra
authors.forename: S
authors.initials: S
authors.lastname: Cesareo
authors.forename: A
authors.initials: A
authors.lastname: Brandimarte
authors.forename: G
authors.initials: G
authors.lastname: Manetti
authors.forename: A
authors.initials: A
authors.lastname: Bovino
authors.forename: P
authors.initials: P
authors.lastname: Sammartino
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002278:Carcinoma in Situ / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D011379:Prognosis; D011879:Radiotherapy Dosage; D012086:Reoperation