[The involvement and reparative regeneration of the mucosa of the airways in thermal inhalation trauma in burn patients].
The adaptive reorganization in mucosa of the upper airways was investigated in 15 burned patients during the first 24 days postburn using historadiography in vitro. The fibreoptic bronchoscopic biopsy specimens obtained in vivo were analysed. The initial significant destructive changes in mucosa and inhibition of DNA and RNA synthesis in the epitheliocytes were changed at day 8 postburn by the development of consecutively arising regenerative processes. The intensification levels of proliferative and metabolic reactions obtained under conditions of the serial bronchoscopies represent important diagnostic and prognostic criteria.
Ustinov
T S
TS
Panova
N V
NV
Glushchenko
E V
EV
Alekseev
A A
AA
Kurbanov
Sh A
ShA
D000222:Adaptation, Physiological; D000328:Adult; D001345:Autoradiography; D001706:Biopsy; D001980:Bronchi / Q000503:physiopathology*; D001999:Bronchoscopy; D002059:Burns, Inhalation / Q000503:physiopathology*; D004247:DNA / Q000096:biosynthesis; D005336:Fiber Optic Technology; D006801:Humans; D008875:Middle Aged; D009092:Mucous Membrane / Q000503:physiopathology; D012313:RNA / Q000096:biosynthesis; D012038:Regeneration / Q000502:physiology*; D013997:Time Factors; D014132:Trachea / Q000503:physiopathology*
D012313:RNA; D004247:DNA