[A favorable result of immunosuppressive therapy combined with the use of cyclosporine in a case of particularly severe Wegener's granuloma].
A case of a 38-year male patient treated for severe Wegener's granuloma has been presented. Immunosuppressive therapy including cyclophosphamide and prednisone produced a 4-week improvement followed by relapsed with advanced organ involvement (severe cardio-respiratory and renal failure). Intensive therapy with cyclosporine A and prednisone (given intravenously and next orally) carried out for 4 months produced a favourable response with complete regression of organ involvement. Actually, the patient is living in a complete remission since 4 years, and takes no drugs since 1 year.
Krzemień
S
S
Kliniki Hematologii Sl. AM w Katowicach.
Wacławik
A
A
Hołowiecki
J
J
Strzelczyk
S
S
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use*; D016572:Cyclosporine / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D014890:Granulomatosis with Polyangiitis / Q000188:drug therapy*; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D012074:Remission Induction
D016572:Cyclosporine; D003520:Cyclophosphamide; D011241:Prednisone