Anaphylaxis to carboplatin following multiple previous uncomplicated courses.
Hypersensitivity reactions to carboplatin are rare but potentially life-threatening complications. A patient with an anaphylactic reaction to carboplatin is presented. This patient had received multiple courses of platinum-based chemotherapy including cisplatin and carboplatin. Close patient monitoring during chemotherapy is essential and skin testing to identify the etiologic agent is indicated when hypersensitivity reactions occur in the setting of combination chemotherapy.
Sood
A K
AK
Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville 32610-0294, USA.
Gelder
M S
MS
Huang
S W
SW
Morgan
L S
LS
D000230:Adenocarcinoma / Q000188:drug therapy; D000707:Anaphylaxis / Q000139:chemically induced* / Q000473:pathology; D016190:Carboplatin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy; D012882:Skin Tests
D016190:Carboplatin