Salivary up-regulation of human polymorphonuclear leucocyte chemotaxis and adhesion-molecule expression.
Chemotaxis and adhesion molecules were investigated in peripheral blood neutrophils incubated with saliva collected from healthy donors. A salivary concentration of 20% increased chemotactic responses and CD11a/CD18 and CD11b/CD18 expression, but had no effect on formyl-methionyl-leucyl-phenylalanine receptors.
Pettini
F
F
Odontostomatologic Clinic, University of Bari, Italy.
Pettini
P
P
Laforgia
A
A
Coluccia
M
M
De Rinaldis
P
P
Fumarulo
R
R
D000328:Adult; D018845:CD11 Antigens / Q000096:biosynthesis / Q000276:immunology; D018821:CD18 Antigens / Q000096:biosynthesis / Q000276:immunology; D002634:Chemotaxis, Leukocyte / Q000276:immunology*; D003773:Dental Plaque / Q000276:immunology; D006801:Humans; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000276:immunology / Q000378:metabolism; D018375:Neutrophil Activation; D009504:Neutrophils / Q000276:immunology*; D044042:Receptors, Formyl Peptide; D011971:Receptors, Immunologic / Q000096:biosynthesis / Q000276:immunology; D016028:Receptors, Leukocyte-Adhesion / Q000096:biosynthesis* / Q000276:immunology; D018000:Receptors, Peptide / Q000096:biosynthesis / Q000276:immunology; D012463:Saliva / Q000276:immunology*; D015854:Up-Regulation
D018845:CD11 Antigens; D018821:CD18 Antigens; D044042:Receptors, Formyl Peptide; D011971:Receptors, Immunologic; D016028:Receptors, Leukocyte-Adhesion; D018000:Receptors, Peptide; D009240:N-Formylmethionine Leucyl-Phenylalanine