title: A second case of trisomy 8 in Philadelphia chromosome (Ph)-negative cells during the course of Ph-positive chronic myelocytic leukemia.
abstract: A Ph-positive CML patient who had received a peripheral blood stem cell autograft in chronic phase demonstrated a transient regression of the Ph-positive clone with the concurrent appearance of another clone with trisomy 8. This latter clone disappeared when the patient received alpha-interferon.
authors.forename: C
authors.initials: C
authors.lastname: Bilhou-Nabera
authors.forename: G
authors.initials: G
authors.lastname: Marit
authors.forename: I
authors.initials: I
authors.lastname: Devianne
authors.forename: F
authors.initials: F
authors.lastname: Viard
authors.forename: S
authors.initials: S
authors.lastname: Salzes
authors.forename: M
authors.initials: M
authors.lastname: Montastruc
authors.forename: M
authors.initials: M
authors.lastname: Renoux
authors.forename: A
authors.initials: A
authors.lastname: Broustet
authors.forename: J
authors.initials: J
authors.lastname: Reiffers
authors.forename: P
authors.initials: P
authors.lastname: Bernard
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D016465:Bone Marrow Purging / Q000009:adverse effects; D002898:Chromosomes, Human, Pair 8; D002999:Clone Cells / Q000648:ultrastructure; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000473:pathology*; D010677:Philadelphia Chromosome; D014314:Trisomy