Human protein factor of fertility and spontaneous abortion.
The concentration of human protein factor of fertility (PFF) in seminal plasma was measured by a semi-quantitative immunodiffusion method with the standard test system. Fresh seminal plasma from 202 men with normal fertility was investigated. The levels of PFF ranged from 2 to 512 mg/l in normospermic specimens. The retrospective analysis revealed a positive correlation (p < 0.001) between low PFF concentration (2-8 mg/l) in the husband's seminal plasma and primary early spontaneous abortion in the wife.
Tatarinov
Y S
YS
Department of Biochemistry, Russian State Medical University, Moscow.
Posiseeva
L V
LV
Belyankin
E V
EV
D000026:Abortion, Habitual / Q000209:etiology; D000022:Abortion, Spontaneous / Q000209:etiology*; D000510:Alpha-Globulins / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D012661:Semen / Q000737:chemistry*
D000510:Alpha-Globulins; D006063:Chorionic Gonadotropin; C025782:chorionic alpha(2)-microglobulin