[Chronic heat stress modulates the immune system in the preclinical phase of murine lupus erythematosus].
Repetitive thermal stress induces a reduction in the characteristic Thy1.2+B220+ lymphocyte subpopulation in lupus mice which were studied before the onset of disease. The immunomodulating effect was systemic, and alterations were not related to corticosterone serum levels.
Becker
H
H
Medizinische Klinik III und Poliklinik, Universität Giessen.
Franz
O
O
Hinckel
P
P
Holzträger
H
H
Federlin
K
K
D000818:Animals; D000954:Antigens, Surface / Q000032:analysis; D015704:CD4 Antigens / Q000032:analysis; D016827:CD8 Antigens / Q000032:analysis; D006358:Hot Temperature; D017493:Leukocyte Common Antigens; D008180:Lupus Erythematosus, Systemic / Q000503:physiopathology*; D016131:Lymphocyte Subsets / Q000276:immunology*; D008562:Membrane Glycoproteins / Q000032:analysis; D051379:Mice; D008817:Mice, Mutant Strains; D016201:Receptors, Lymphocyte Homing / Q000032:analysis; D018800:Thy-1 Antigens
D000954:Antigens, Surface; D015704:CD4 Antigens; D016827:CD8 Antigens; D008562:Membrane Glycoproteins; D016201:Receptors, Lymphocyte Homing; D018800:Thy-1 Antigens; D017493:Leukocyte Common Antigens