HeLa D98/aH-2 studied by chromosome painting and conventional cytogenetical techniques.
Metaphase chromosomes of HeLa D98/AH-2 cells were studied by GTG-banding, NOR-silver staining and in situ hybridization using libraries specific for each human chromosome as probes (chromosome painting). The structure and composition of all marker chromosomes could be determined, allowing a critical assessment of earlier studies. The revised HeLa D98/AH-2 karyotype should provide a reference standard in certain cancer cytogenetic studies.
Ruess
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Deutsches Krebsforschungs-Zentrum, Heidelberg, Germany.
Ye
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LZ
Grond-Ginsbach
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C
D002871:Chromosome Banding; D002877:Chromosomes, Human; D003582:Cytogenetics; D005819:Genetic Markers; D005821:Genetic Techniques; D006367:HeLa Cells / Q000648:ultrastructure*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D013194:Staining and Labeling
D005819:Genetic Markers