[A trial of the use of the preparation Arthrotec for treating rheumatic diseases].
A clinical trial of arthrotek (Searle) in 60 RA patients aged 16-77 years demonstrated its high anti-inflammatory activity in 47 of them. These patients have received a complete treatment course, 10 patients were not included in the overall estimations because of side affects (gastric pains and nausea) causing them to withdraw early in the treatment course, 3 patients were nonresponders. The responders experienced attenuation of joint pain, morning stiffness. Inflammation in some joints declined, the articular index decreased.
Nasonova
V A
VA
Sigidin
Ia A
IaA
Murav'ev
Iu V
IuV
Lebedeva
O I
OI
Burtsev
V I
VI
Rashchupkina
Z P
ZP
Krikunov
V P
VP
Kuzin
A V
AV
Nasonov
E L
EL
Chichasova
N V
NV
D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D004008:Diclofenac / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016595:Misoprostol / Q000009:adverse effects / Q000627:therapeutic use*; D012074:Remission Induction; D012216:Rheumatic Diseases / Q000175:diagnosis / Q000188:drug therapy*; D012426:Russia; D013607:Tablets
D000894:Anti-Inflammatory Agents, Non-Steroidal; C078133:Arthrotec; D004338:Drug Combinations; D013607:Tablets; D016595:Misoprostol; D004008:Diclofenac