title: Rearrangement of band q13 on both chromosomes 12 in a periosteal chondroma.
abstract: Cytogenetic analysis of a recurrent periosteal chondroma revealed nonreciprocal translocations of both chromosomal segments 12q13-->qter, from one chromosome 12 to 7q32 and from the homologous chromosome 12 to 16q22. The remaining parts of the two chromosomes 12 formed a dicentric chromosome. This is the second reported chondroma with a 12q13-15 rearrangement, and changes of this chromosome region consequently seem to be nonrandom occurrences in chondromas.
authors.affiliation: Department of Clinical Genetics, University Hospital, Lund, Sweden.
authors.forename: N
authors.initials: N
authors.lastname: Mandahl
authors.forename: H
authors.initials: H
authors.lastname: Willén
authors.forename: A
authors.initials: A
authors.lastname: Rydholm
authors.forename: S
authors.initials: S
authors.lastname: Heim
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D000328:Adult; D002812:Chondroma / Q000235:genetics*; D002881:Chromosomes, Human, Pair 12 / Q000648:ultrastructure*; D002885:Chromosomes, Human, Pair 16 / Q000648:ultrastructure*; D002897:Chromosomes, Human, Pair 7 / Q000648:ultrastructure; D005266:Femoral Neoplasms / Q000235:genetics*; D015321:Gene Rearrangement; D006801:Humans; D007621:Karyotyping; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000235:genetics; D014178:Translocation, Genetic