The effect of non-mutagenic stress on liquid holding recovery in Escherichia coli AB2463.
Previous work has shown that exposure to many non-mutagenic stresses causes greater UV resistance in Escherichia coli K12 via an error-free, excision repair-dependent process. Induction of the latter should enhance liquid holding recovery in the bacteria. The results in this paper show that this is the case and that the increased UV-resistance is due entirely to an increase in the capacity of the cells for DNA excision repair. The latter arises wholly or in part from an increase in the intracellular level of the key enzyme of the pathway, UvrABC endonuclease.
Fitt
P S
PS
Department of Biochemistry, University of Ottawa, Canada.
Sharma
N
N
D002110:Caffeine / Q000494:pharmacology; D004260:DNA Repair; D004706:Endodeoxyribonucleases / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D029968:Escherichia coli Proteins; D005947:Glucose / Q000378:metabolism; D011938:Rec A Recombinases / Q000235:genetics; D014466:Ultraviolet Rays
D029968:Escherichia coli Proteins; D002110:Caffeine; D011938:Rec A Recombinases; D004706:Endodeoxyribonucleases; C036385:endodeoxyribonuclease uvrABC; D005947:Glucose