title: [Quality assurance in autologous blood collection from critically ill patients].
abstract: Quality controls of autologous blood collections in critically ill patients comprise the control of blood products, blood collection, and of the patients themselves. The control of products is defined in European guidelines, the AMG (law governing the manufacture and prescription of medicine) and GMP regulations. The products are described in the monograph of the Federal Health Office. The quality control of blood collection in patients with a critical vascular disease is important since vagotonic or hypertensive crises may occur frequently (in 10-15% of cardiosurgical patients). The quality control of the critically ill patients themselves is important in order to be able to balance benefits against risks. A phlebotomy of 500 ml may lead to a considerable deterioration of the clinical condition. The clinical condition can be controlled by simple exercise tests prior to and after the blood collection (bicycle ergometer, treadmill or climbing stairs). In our own investigations only about 25% of cardiosurgical patients (40% of patients with aortocoronary venous bypass) received autohemotherapy, and 20% of them showed a clinical deterioration during the phase of blood collection. Other problematic patients are those suffering from a tumor. A clear clinical benefit of autohemotherapy in these patients has not been demonstrated up to now; nevertheless, when a curative therapy is possible, they should be treated with autohemotherapy.
authors.affiliation: Abteilung für Klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, Homburg/Saar, BRD.
authors.forename: H
authors.initials: H
authors.lastname: Kiesewetter
authors.forename: F
authors.initials: F
authors.lastname: Jung
authors.forename: J
authors.initials: J
authors.lastname: Koscielny
authors.forename: G
authors.initials: G
authors.lastname: Pindur
authors.forename: E
authors.initials: E
authors.lastname: Wenzel
mesh_terms: D001804:Blood Transfusion, Autologous; D015179:Colorectal Neoplasms / Q000097:blood / Q000601:surgery; D000075202:Contraindications; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000097:blood / Q000601:surgery; D003422:Critical Care; D006801:Humans; D011785:Quality Assurance, Health Care; D012307:Risk Factors