Bulbospinal augmenting inspiratory neurons may participate in contractions of the diaphragm during vomiting in decerebrate dogs.
Contradictory results have been reported regarding the participation of bulbospinal inspiratory (BSI) neurons in vomiting contractions of the diaphragm in dogs and cats maintained at low and high end-tidal CO2 levels, respectively. To resolve this discrepancy, effects of CO2 levels on vomiting activities were observed in 159 BSI-neurons of paralyzed decerebrate dogs. About half of the BSI-neurons exhibited a vigorous burst with each fictive retch regardless of the CO2 level and 28 of 51 BSI-neurons produced a burst during the early phase of expulsion. These BSI-neurons were not concentrated in any particular area. While these results do not resolve the above contradiction, they do suggest that some BSI-neurons participate in the vomiting contraction of the diaphragm.
Koga
T
T
Department of Physiology, Kawasaki Medical School, Kurashiki, Japan.
Fukuda
H
H
D000009:Abdominal Muscles / Q000294:innervation / Q000503:physiopathology; D000200:Action Potentials; D000818:Animals; D001933:Brain Stem / Q000503:physiopathology*; D002245:Carbon Dioxide / Q000097:blood; D003655:Decerebrate State / Q000503:physiopathology*; D003964:Diaphragm / Q000294:innervation / Q000503:physiopathology*; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D001239:Inhalation / Q000502:physiology; D008297:Male; D009119:Muscle Contraction; D009476:Neurons, Efferent / Q000502:physiology*; D010791:Phrenic Nerve / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology*; D014630:Vagus Nerve / Q000503:physiopathology; D014839:Vomiting / Q000503:physiopathology*
D002245:Carbon Dioxide