Renal tubular disorders and arteriopathy of the lower limbs: risk factors for osteoporosis in men?
In order to clarify the risk-factors for men with vertebral fractures due to osteoporosis, we carried out a study of 51 cases. Twenty-five percent of patients had an endocrine disorder (hyperparathyroidism, hypogonadism, hyperthyroidism) or had received corticosteroids. These patients were compared with 26 age-matched controls. Eleven patients compared with 2 of the 26 control subjects had arteriopathy of the lower limbs; 11 patients had hypercalciuria or hyperphosphaturia compared with 3 of the control subjects. Arteriopathy appears to be associated with osteoporosis in older patients (mean age 71 years), whereas renal tubular disorders were found in younger patients (mean age 45 years).
Laroche
M
M
Service de Rhumatologie, Centre Hospitalier et Universitaire Rangueil, Toulouse, France.
Moulinier
L
L
Bon
E
E
Cantagrel
A
A
Mazieres
B
B
D000368:Aged; D000437:Alcoholism / Q000150:complications; D001161:Arteriosclerosis / Q000150:complications*; D001639:Bicarbonates / Q000652:urine*; D002118:Calcium / Q000652:urine*; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D006980:Hyperthyroidism / Q000150:complications; D007006:Hypogonadism / Q000150:complications; D007015:Hypophosphatemia, Familial / Q000652:urine*; D008159:Lumbar Vertebrae / Q000293:injuries; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000209:etiology*; D011446:Prospective Studies; D012307:Risk Factors; D012907:Smoking
D001639:Bicarbonates; D002118:Calcium