[Benign enlargement of the thymus after chemotherapy of metastasizing testicular cancer].
A young male with retroperitoneal recurrence of a germ cell tumour was successfully treated with chemotherapy. Four months after the last treatment a CT scan revealed hyperplasia of the thymus. A year after the last treatment the CT scan shows regression. A review of the literature demonstrates that 10% of patients treated for germ cell tumours develop a benign, reversible hyperplasia of the thymus within two years after treatment. Thus, benign hyperplasia of the thymus should be considered if a patient treated for germ cell tumour develops a tumour in the anterior mediastinum within two years.
Hansen
L J
LJ
Onkologisk-haematologisk afdeling R, Odense Sygehus.
Madsen
E L
EL
Møller
M N
MN
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D005047:Etoposide / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000556:secondary*; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000556:secondary*; D013952:Thymus Hyperplasia / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin