title: [Psychiatric changes caused by epileptic seizures].
abstract: Frequent tonic-clonic seizures could probably lead to psychic disorders. In various studies a decrease in at least single functions of mental capability was found depending on the frequency of the seizures and/or the duration and/or the age of onset of the disease. The development of neuropsychological deficits depends on the type of seizures. Particularly BNS-seizures and the Lennox-Gastaut-syndrome have generally a poor prognosis concerning the intellectual development. Not only clinically manifest seizures but also subclinical discharges could disturb the psychic condition of epileptic patients. Epileptic seizures are probably a reason for neuronal damage in the hippocampus area. Psychogenic reactions and undesired effects of antiepileptic drugs have to be considered aside from functional disturbances due to epileptic seizures.
authors.affiliation: Neurologische Abteilung, Psychiatrisches Landeskrankenhaus Weissenau, Abteilung Psychiatrie I der Universität Ulm, Ravensburg.
authors.forename: W
authors.initials: W
authors.lastname: Fröscher
authors.forename: K D
authors.initials: KD
authors.lastname: Neher
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000523:psychology; D011379:Prognosis; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000523:psychology
chemical_list: D000927:Anticonvulsants