Long QT syndrome during high-dose cisapride.
The gastrointestinal prokinetic drug, cisapride, is widely used for the treatment of diabetic gastroparesis and disorders of gastrointestinal motility. We present a case of acquired QT prolongation, syncope, and nonsustained ventricular tachycardia associated with high doses of cisapride.
Bran
S
S
Veterans Affairs Medical Center, Seattle.
Murray
W A
WA
Hirsch
I B
IB
Palmer
J P
JP
D020117:Cisapride; D004562:Electrocardiography; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000009:adverse effects*
D005765:Gastrointestinal Agents; D010880:Piperidines; D020117:Cisapride