title: [Immunoblotting analysis of acquired factor VIII inhibitor in an elderly man].
abstract: A case of acquired FVIII inhibitor in a nonhemophilic, 80 year-old man who had no underlying disorder, is presented. The level of inhibitor was 13.3 Bethesda unit/ml, and the antibody was IgG, with lambda light chain. The antibody reacted with the 92 kD fragment of non-treated human FVIII, and the 44 kD fragment of thrombin treated FVIII when analysed by the immunoblot analysis.
authors.affiliation: Department of Internal Medicine, Saga Medical School.
authors.forename: M
authors.initials: M
authors.lastname: Kikuchi
authors.forename: M
authors.initials: M
authors.lastname: Sano
authors.forename: Y
authors.initials: Y
authors.lastname: Shimamoto
authors.forename: M
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: J
authors.initials: J
authors.lastname: Tadano
authors.forename: I
authors.initials: I
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Kamiya
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000906:Antibodies / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D008297:Male
chemical_list: D000906:Antibodies; D000939:Epitopes; D005169:Factor VIII