[Small airway obstruction in patients with idiopathic interstitial pneumonia (IIP)--comparison between acute and chronic types].
Small airway obstruction in patients with acute and chronic interstitial pneumonia was studied. Patients with acute interstitial pneumonia (IP, n = 3), and with acute exacerbation of chronic IP (n = 4) were studied as a group, and were compared to patients with chronic idiopathic interstitial pneumonia (IIP, n = 41). Small airway obstruction was defined on a logarithmic %VC-V25/VC plane, because the V25/VC (an index of both small airway obstruction and decreased lung compliance) depended on %VC. Six of seven patients (86%) with acute IP and 8 of 42 patients (19.5%) with chronic IIP had small airway obstruction (p < 0.01). Small airway obstruction was often seen in acute IP, but was not often seen in chronic IIP.
Zhou
C
C
Department of Internal Medicine, Tokyo National Chest Hospital, Japan.
Nagayama
N
N
Ohtsuka
Y
Y
Nagai
H
H
Shishido
H
H
Sato
K
K
Kurashima
A
A
Hebisawa
A
A
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000402:Airway Obstruction / Q000209:etiology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications*; D008297:Male; D008875:Middle Aged