Mapping of the human TATA-binding protein gene (TBP) to chromosome 6qter.
TATA-binding protein (TBP) is a general transcription factor involved in transcriptional initiation. We have used oligonucleotide primers flanking a polymorphic stretch of 38 glutamine codons in the 5' coding region of the TBP gene to genetically map this gene. We report the location of the human TBP gene to be at 6qter.
Rosen
D R
DR
Day Neuromuscular Research Laboratory, Massachusetts General Hospital, Charlestown, USA.
Trofatter
J A
JA
Brown
R H
RH
D001483:Base Sequence; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D004268:DNA-Binding Proteins / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008126:Lod Score; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D016385:TATA Box / Q000235:genetics*; D035181:TATA-Box Binding Protein; D014157:Transcription Factors / Q000235:genetics*
D004268:DNA-Binding Proteins; D005819:Genetic Markers; D035181:TATA-Box Binding Protein; D014157:Transcription Factors