Antibiotic therapeutics in laboratory animals.
Information on antibiotic therapeutics in laboratory species, especially in rodents and rabbits, is reviewed. A number of areas are considered: interference by antibiotics with an experiment, antibiotic toxicity, routes of administration, effects of formulation on bioavailability, antibiotic prophylaxis, use of combinations of antibiotics, misuse of antibiotics, regulatory approval for antibiotic use in animals, sources of information on antibiotic indications and dose, and extrapolation of dose information from other species.
Morris
T H
TH
Department of Laboratory Animal Science, SmithKline Beecham Pharmaceuticals, Harlow, Essex, UK.
D000820:Animal Diseases / Q000188:drug therapy*; D000818:Animals; D000830:Animals, Laboratory; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control / Q000662:veterinary; D013045:Species Specificity
D000900:Anti-Bacterial Agents