Patch-clamp studies of the oxytocin-induced effects in Helix pomatia L. neurons.
Effect of extracellularly applied oxytocin was investigated on snail neurons in cell attached single channel recording configuration. OXT activated Cl-dependent inward and outward current with amplitude of 1.4 and 1.6 pA, respectively. OXT have affected the ACh-activated current decreasing or increasing the mean interburst interval of single channel activity.
Osipenko
O
O
Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.
Kiss
T
T
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D018118:Chloride Channels; D002712:Chlorides / Q000494:pharmacology; D005071:Evoked Potentials / Q000187:drug effects; D005724:Ganglia / Q000502:physiology; D006372:Helix, Snails; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology; D008565:Membrane Proteins / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010121:Oxytocin / Q000494:pharmacology*
D018118:Chloride Channels; D002712:Chlorides; D007473:Ion Channels; D008565:Membrane Proteins; D010121:Oxytocin; D000109:Acetylcholine