title: Tumefactive fibroinflammatory lesion of the head and neck: a management strategy.
abstract: Tumefactive fibroinflammatory lesions are rare, benign, fibrosclerosing masses in the head and neck that appear clinically as malignancies. Twenty-one cases have been described since first reported in 1975. While all authors agree on the lesion's histopathologic characteristics, multiple variations in appearance, treatment, and results have been reported. We review a case and compile all previously reported cases. Common sites of involvement were sinonasal tract (41%), neck (37%), and parotid (23%). Symptoms frequently reported were pain (50%) and hard mass (55%). Five patients (23%) eventually developed extra-head and neck fibrosclerosing lesions. Treatments have included surgery, radiation, and corticosteroids, occasionally in combination. Results have varied depending on size and location of lesion. Based on this review, a discussion of this rare disease and recommendations regarding diagnosis and treatment are given.
authors.affiliation: University of Iowa Hospitals and Clinics, Department of Otolaryngology, Iowa City 52242.
authors.forename: J F
authors.initials: JF
authors.lastname: Laurenzo
authors.forename: S M
authors.initials: SM
authors.lastname: Graham
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005355:Fibrosis; D006258:Head and Neck Neoplasms / Q000175:diagnosis; D006801:Humans; D008297:Male; D010254:Paranasal Sinus Diseases / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D010305:Parotid Diseases / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use; D012598:Sclerosis
chemical_list: D011241:Prednisone