title: [Ligenten--a combination drug with anesthetic and antibacterial action for local use in urology and gynecology].
abstract: Ligenten gel is a combined dosage form containing gentamicin (a broad spectrum antibiotic), lidocaine (an anesthetic) and ethonium (an antiseptic). The hydrogel sodium carboxymethylcellulose in combination with polyvinylpyrrolidone is used as the ligenten base. The clinical trials in urologic and gynecologic patients showed that ligenten had a high therapeutic efficacy in the treatment of inflammatory diseases, as well as an anesthetic action in instrumental examinations and surgical endoscopic manipulations.
authors.forename: A F
authors.initials: AF
authors.lastname: Darenkov
authors.forename: T S
authors.initials: TS
authors.lastname: Perepanova
authors.forename: G A
authors.initials: GA
authors.lastname: Kotliarova
authors.forename: L S
authors.initials: LS
authors.lastname: Strachunskiĭ
authors.forename: L V
authors.initials: LV
authors.lastname: Tsibina
authors.forename: E V
authors.initials: EV
authors.lastname: Zharov
authors.forename: S V
authors.initials: SV
authors.lastname: Lebed'
authors.forename: O V
authors.initials: OV
authors.lastname: Makarov
authors.forename: T N
authors.initials: TN
authors.lastname: Savchenko
authors.forename: M M
authors.initials: MM
authors.lastname: Vasil'ev
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002648:Child; D004338:Drug Combinations; D004724:Endoscopy; D052776:Female Urogenital Diseases / Q000175:diagnosis / Q000188:drug therapy*; D005782:Gels; D005839:Gentamicins / Q000494:pharmacology*; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000188:drug therapy; D008012:Lidocaine / Q000494:pharmacology*; D052801:Male Urogenital Diseases; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage* / Q000494:pharmacology*
chemical_list: D000779:Anesthetics, Local; D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D005782:Gels; D005839:Gentamicins; C089167:Ligenten; D000644:Quaternary Ammonium Compounds; C004921:Ethonium; D008012:Lidocaine