[Aggregation of human immunoglobulins under normal conditions and in malignant stomach tumor].
We apply the thermal perturbation difference spectroscopy to demonstrate that immunoglobulins G (IgG) isolated from blood serum of a patient with stomach cancer are more stable to the influence of 12% urea than IgG of a healthy donor. IgG at the same pathology have greater tendency to aggregation than IgG at norm according to the laser correlation spectroscopy data.
Efetov
K A
KA
Arutiunian
A V
AV
D006801:Humans; D007074:Immunoglobulin G / Q000737:chemistry*; D013057:Spectrum Analysis; D013274:Stomach Neoplasms / Q000097:blood*; D014508:Urea
D007074:Immunoglobulin G; D014508:Urea