[The effect of antibodies to microorganisms in a focus of purulent inflammation].
The rats were infected with a suspension of dissociated or agglutinated Pseudomonas aeruginosa [correction of B. pynocyaneus]. Infection with the agglutinated agent drastically improved the clinical course, lowered the indices of the process generalization (mortality, metastatic foci, spread in the internal organs); no hemorrhages, necrosis or abscesses were noted. A rapid (within the first day) death of almost all agglutinated bacteria in the primary focus was observed, this not being due to phagocytosis or complement-dependent lysis.
Pal'tsyn
A A
AA
Kolokol'chikova
E G
EG
Grishina
I A
IA
Chervonskaia
N V
NV
Badikova
A K
AK
Popova
E P
EP
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D005490:Focal Infection / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D007106:Immune Sera / Q000008:administration & dosage; D007273:Injections, Intramuscular; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D011552:Pseudomonas Infections / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D011550:Pseudomonas aeruginosa / Q000276:immunology* / Q000302:isolation & purification; D051381:Rats; D018805:Sepsis / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D013154:Spleen / Q000382:microbiology / Q000473:pathology; D013997:Time Factors
D000907:Antibodies, Bacterial; D007106:Immune Sera