title: Giant-cell tumours with fracture at diagnosis. Curettage and acrylic cementing in ten cases.
abstract: Between 1971 and 1991 we treated 98 patients with giant-cell tumours, 15 of whom presented with a pathological fracture. They were most common around the knee (12). Nine fractures were intra-articular. The tumours were treated by curettage and acrylic cementing (10), excision and endoprosthesis (1), excision and allograft (1), curettage and autologous graft (2) or by resection of the fibular head (1). Four patients had local recurrence, three of whom were cured by repeat curettage and cementing. Pathological fracture through a giant-cell tumour is not a contraindication to treatment by curettage and acrylic cementing.
authors.affiliation: University Hospital, Lund, Sweden.
authors.forename: K E
authors.initials: KE
authors.lastname: Dreinhöfer
authors.forename: A
authors.initials: A
authors.lastname: Rydholm
authors.forename: H C
authors.initials: HC
authors.lastname: Bauer
authors.forename: A
authors.initials: A
authors.lastname: Kreicbergs
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000150:complications / Q000601:surgery*; D016025:Bone Transplantation; D002648:Child; D003475:Curettage; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology / Q000601:surgery; D018212:Giant Cell Tumor of Bone / Q000150:complications / Q000601:surgery*; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging; D008297:Male; D008768:Methylmethacrylates / Q000627:therapeutic use; D008875:Middle Aged; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D008768:Methylmethacrylates