title: Intra-arterial administration of adriamycin-loaded albumin microspheres for locally advanced breast cancer.
abstract: Regional chemotherapy is an attractive but underevaluated method of treating locally advanced breast cancer. We have combined two novel methods of targeting by delivering a single pulse of adriamycin-loaded albumin microspheres down a radiologically placed internal mammary artery catheter. A complete response was observed and prolonged local control achieved.
authors.affiliation: University Department of Surgery, Royal Infirmary, Glasgow, UK.
authors.forename: J C
authors.initials: JC
authors.lastname: Doughty
authors.forename: J H
authors.initials: JH
authors.lastname: Anderson
authors.forename: N
authors.initials: N
authors.lastname: Willmott
authors.forename: C S
authors.initials: CS
authors.lastname: McArdle
mesh_terms: D000328:Adult; D000418:Albumins; D001943:Breast Neoplasms / Q000188:drug therapy*; D002406:Catheterization, Peripheral; D004317:Doxorubicin / Q000008:administration & dosage*; D016503:Drug Delivery Systems / Q000379:methods*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008863:Microspheres
chemical_list: D000418:Albumins; D004317:Doxorubicin