title: Efferents of frontal or occipital cortex grafted into adult rat's motor cortex.
abstract: Phaseolus vulgaris leucoagglutinin (PHA-L) was used to examine the efferent connectivity of embryonic (E16) frontal (homotopic) or occipital (heterotopic) neocortical transplants placed into--or in the vicinity of--lesion cavities made in the frontal cortex of adult recipients. Homotopic transplants projected towards the host sensorimotor cortex and, in most cases, into the lateral caudate-putamen (CPu). Heterotopic transplants projected into the anterior cingulate cortex and, in most cases, distributed terminals into the medial CPu. It is suggested that embryonic neocortical tissue placed into a damaged cortical site of an adult recipient develops a pattern of efferents corresponding to its cortical origin.
authors.affiliation: Laboratoire de Neurophysiologie, CNRS, URA 1869, Université de Poitiers, Faculté des Sciences, France.
authors.forename: J
authors.initials: J
authors.lastname: Guitet
authors.forename: C
authors.initials: C
authors.lastname: Garnier
authors.forename: A
authors.initials: A
authors.lastname: Ebrahimi-Gaillard
authors.forename: M
authors.initials: M
authors.lastname: Roger
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000601:surgery; D016380:Brain Tissue Transplantation; D002421:Caudate Nucleus; D004525:Efferent Pathways / Q000648:ultrastructure*; D016332:Fetal Tissue Transplantation; D005625:Frontal Lobe / Q000196:embryology / Q000637:transplantation*; D006085:Graft Survival; D006179:Gyrus Cinguli; D009044:Motor Cortex / Q000502:physiology / Q000601:surgery; D009778:Occipital Lobe / Q000196:embryology / Q000637:transplantation*; D010835:Phytohemagglutinins; D011699:Putamen; D051381:Rats; D017208:Rats, Wistar; D016042:Transplantation, Heterotopic
chemical_list: D010835:Phytohemagglutinins; C100156:leukoagglutinins, plants