title: D2 dopamine receptor mRNA distribution in cholinergic and somatostatinergic cells of the rat caudate-putamen and nucleus accumbens.
abstract: An in situ hybridization procedure that identifies cells expressing D2 dopamine receptor mRNA was combined in double-labelling studies with immunohistochemical procedures that identify cells expressing either choline acetyltransferase (ChAT) or somatostatin. D2 receptor mRNA was detected in almost all of the ChAT positive caudate-putamen cells, approximately half of the ChAT positive nucleus accumbens cells and none of the somatostatin-positive cells in either brain region.
authors.affiliation: Department of Neuroscience, University of Florida College of Medicine, Gainesville 32610.
authors.forename: A J
authors.initials: AJ
authors.lastname: MacLennan
authors.forename: N
authors.initials: N
authors.lastname: Lee
authors.forename: S R
authors.initials: SR
authors.lastname: Vincent
authors.forename: D W
authors.initials: DW
authors.lastname: Walker
mesh_terms: D000109:Acetylcholine / Q000032:analysis*; D000818:Animals; D002421:Caudate Nucleus / Q000737:chemistry* / Q000166:cytology; D002795:Choline O-Acetyltransferase / Q000032:analysis; D007124:Immunoenzyme Techniques; D017403:In Situ Hybridization; D008297:Male; D009474:Neurons / Q000737:chemistry*; D009714:Nucleus Accumbens / Q000737:chemistry* / Q000166:cytology; D011699:Putamen / Q000737:chemistry* / Q000166:cytology; D012333:RNA, Messenger / Q000032:analysis* / Q000096:biosynthesis; D051381:Rats; D017207:Rats, Sprague-Dawley; D017448:Receptors, Dopamine D2 / Q000096:biosynthesis* / Q000235:genetics; D013004:Somatostatin / Q000032:analysis*
chemical_list: D012333:RNA, Messenger; D017448:Receptors, Dopamine D2; D013004:Somatostatin; D002795:Choline O-Acetyltransferase; D000109:Acetylcholine