Surrogate tissues for detecting brain microemboli after cardiopulmonary bypass.
During cardiopulmonary bypass (CPB) microemboli lodge in the brain and other organs. Microemboli were counted in tissue samples of skin, muscle and brain from autopsy cases that had recently undergone CPB, and in skin and muscle biopsies obtained from patients before and after CPB. Unlike the brain, skin and muscle showed few microemboli.
Brown
W R
WR
Department of Radiology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina 27157-1088.
Moody
D M
DM
Mills
S A
SA
Anderson
R L
RL
D001706:Biopsy; D001921:Brain / Q000473:pathology; D002315:Cardiopulmonary Bypass; D004617:Embolism / Q000473:pathology; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000175:diagnosis* / Q000209:etiology*; D009132:Muscles / Q000098:blood supply / Q000473:pathology; D011183:Postoperative Complications; D012867:Skin / Q000098:blood supply / Q000473:pathology