[Early amniocentesis between the 12th-14th week of pregnancy. Clinical experiences with 1,100 cases].
Information is presented on 1100 early amniocenteses between the 12th and 14th week of gestation, performed at the Evangelisches Krankenhaus Oberhausen over a two year period. In all cases, a sufficient amount of amniotic fluid was obtained. In 99.7%, the cytogenetic diagnosis was successful. In 2.6% (29 patients), an aberrant karyotype was found. The time of cultivation was in the same range as can be observed in standard amniocentesis. The AFP-median measurements correlate with other studies. The spontaneous abortion rate was 0.3%. We conclude, that early amniocentesis can be performed safely and successfully by an experienced surgeon between the 12th to 14th week of gestation.
Eiben
B
B
Institut für Klinische Genetik und Frauenklinik, Evangelisches Krankenhaus Oberhausen.
Goebel
R
R
Rutt
G
G
Jaspers
K D
KD
Hansen
S
S
Hammans
W
W
D000022:Abortion, Spontaneous / Q000209:etiology; D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010865:Pilot Projects; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012307:Risk Factors; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins