NOS neurones lie near branchings of cortical arteriolae.
We show that numerous neurones labelled for NADPH-diaphorase, which synthetize nitric oxide, lie near branching points of the arteriolae which descend through the cerebral cortex from its pial surface. This spatial relationship suggests the possibility of neural control of cortical blood flow by the NADPH-diaphorase neurones, possibly mediated by the rapid action of nitric oxide.
Regidor
J
J
Department of Morphology, Faculty of Medical and Health Sciences, University of Las Palmas, Gran Canaria, Spain.
Edvinsson
L
L
Divac
I
I
D000594:Amino Acid Oxidoreductases / Q000378:metabolism*; D000818:Animals; D001160:Arterioles / Q000201:enzymology / Q000648:ultrastructure; D002540:Cerebral Cortex / Q000098:blood supply / Q000201:enzymology / Q000648:ultrastructure*; D002560:Cerebrovascular Circulation / Q000502:physiology; D009252:NADPH Dehydrogenase / Q000378:metabolism; D009474:Neurons / Q000201:enzymology*; D019001:Nitric Oxide Synthase; D051381:Rats
D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D009252:NADPH Dehydrogenase