Impaired wound healing in the cancer patient: effects of cytotoxic therapy and pharmacologic modulation by growth factors.
This article reviews the experimental and clinical data regarding the effects of chemotherapy on wound healing. In addition, the role of growth factors in the normal wound healing process and their therapeutic potential to optimize wound healing in the cancer patient are discussed.
Cornell
K
K
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA.
Waters
D J
DJ
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006133:Growth Substances / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*; D014945:Wound Healing / Q000187:drug effects*
D000970:Antineoplastic Agents; D006133:Growth Substances