title: Antimicrobial activity of beta-lactams against multiresistant micro-organisms from the family Enterobacteriaceae, and genus Pseudomonas.
abstract: The antimicrobial activity of twenty beta-lactams was determined against multiresistant micro-organisms from the Enterobacteriaceae family (450) and the genus Pseudomonas (90). The antimicrobial susceptibility was assessed by the disk diffusion method. The most effective antibiotics were cephalosporins of the second and third generation, and non-classical beta-lactams (imipenem and moxalactam). A pronounced resistance was found to carbenicillin, ampicillin, cephalotin and cefazolin. These resistance patterns corresponded to a high consumption of these antibiotics.
authors.affiliation: Department of Biotechnology, Centre of Pharmaceutical Chemistry, Havana, Cuba.
authors.forename: A
authors.initials: A
authors.lastname: Niebla
authors.forename: I
authors.initials: I
authors.lastname: González
authors.forename: C
authors.initials: C
authors.lastname: Vallín
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018432:Drug Resistance, Multiple; D004755:Enterobacteriaceae / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects*; D018440:beta-Lactam Resistance; D047090:beta-Lactams
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams