Difficulty in the staging of Hodgkin's disease due to the coexistence of reactive lymphadenopathy.
We report a patient in whom Stage 1A Hodgkin's Disease was established by lymph node biopsy and radiology. Further lymphadenopathy developed accompanied by sweats and fever. Initially this was thought to represent further extensive Hodgkin's disease however repeat biopsy of the newly enlarged nodes showed reactive changes only. We discuss the importance of histological staging in this disease.
Richards
E M
EM
Department of Haematology, Addenbrooke's Hospital, Cambridge, UK.
Marcus
R E
RE
D000328:Adult; D000910:Antibodies, Heterophile / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D004854:Herpesvirus 4, Human; D006689:Hodgkin Disease / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009367:Neoplasm Staging; D011859:Radiography; D012074:Remission Induction; D014747:Vinblastine / Q000008:administration & dosage
D000910:Antibodies, Heterophile; D000914:Antibodies, Viral; D001761:Bleomycin; D014747:Vinblastine; D008727:Methotrexate