Surgical experience on patients with serum lupus anticoagulants. A report of two cases.
Lupus anticoagulants (LA) are antiphospholipid IgG, IgM, or IgA auto antibodies. When LAs are present, a prolongation of activated partial thromboplastin time is usually found and arteriovenous thrombosis is likely to occur during or after surgery. We report here two LA-positive cases (a 29-year-old male taking chlorpromazine for schizophrenia, and a 44-year-old female diagnosed as systemic lupus erythematosus) who underwent surgical procedures without complications.
Minezaki
T
T
Department of Orthopaedic Surgery, Tokai University School of Medicine, Kanagawa, Japan.
Ichikawa
Y
Y
D000328:Adult; D001174:Arthrodesis; D002746:Chlorpromazine / Q000009:adverse effects*; D005260:Female; D005271:Femur Head Necrosis / Q000150:complications / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D008180:Lupus Erythematosus, Systemic / Q000097:blood* / Q000150:complications / Q000188:drug therapy; D008297:Male; D012559:Schizophrenia / Q000188:drug therapy; D013978:Tibial Fractures / Q000601:surgery
D016682:Lupus Coagulation Inhibitor; D002746:Chlorpromazine