title: Effect of delayed specimen processing on cytomegalovirus antigenemia test results.
abstract: Blood samples held at either 4 degrees C or room temperature for 1 day had similar mean decreases in number of cytomegalovirus antigenemia-positive cells (52 to 55%) and similar false-negative test results (13 to 14%). After 2 days, samples held at 4 degrees C showed no further decline, whereas samples held at room temperature had a mean 81% decrease in positive cells, a 32% false-negative rate, and a more marked deterioration in cell morphology.
authors.affiliation: Clinical Virology Laboratory, Yale New Haven Hospital, Connecticut 06510.
authors.forename: M L
authors.initials: ML
authors.lastname: Landry
authors.forename: D
authors.initials: D
authors.lastname: Ferguson
authors.forename: S
authors.initials: S
authors.lastname: Cohen
authors.forename: K
authors.initials: K
authors.lastname: Huber
authors.forename: P
authors.initials: P
authors.lastname: Wetherill
mesh_terms: D000956:Antigens, Viral / Q000097:blood*; D016026:Bone Marrow Transplantation; D003080:Cold Temperature; D003586:Cytomegalovirus Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D005188:False Negative Reactions; D005455:Fluorescent Antibody Technique; D015658:HIV Infections / Q000150:complications; D006358:Hot Temperature; D006801:Humans; D007962:Leukocytes / Q000821:virology; D010750:Phosphoproteins / Q000097:blood; D013048:Specimen Handling; D013997:Time Factors; D014763:Viral Matrix Proteins / Q000097:blood
chemical_list: D000956:Antigens, Viral; D010750:Phosphoproteins; D014763:Viral Matrix Proteins; C065418:cytomegalovirus matrix protein 65kDa