title: Isolation of Theileria parva (SAO Hill) and Theileria parva (West Kilimanjaro) and their cross-immunity with Theileria parva (Kasoba).
abstract: Two Theileria parva stocks were isolated from control cattle during East Cost fever (ECF) field immunization trials at SAO Hill and West Kilimanjaro in the southern and northern parts of Tanzania respectively. Both parasite stocks caused severe clinical ECF which required antitheilerial treatment for 3 of the 5 experimentally infected cattle. Cattle recovering from infection with the two T. parva stocks did not develop a fever and only 1 of 4 animals developed scanty schizont parasitosis for one day during a challenge with T. parva (Kasoba) from northern Malawi. In contrast, both control cattle developed fever and schizonts, and one required antitheilerial treatment to survive.
authors.affiliation: East Coast Fever Vaccine Production, Quality Control and Immunization Project RAF/92/010, Lilongwe, Malawi.
authors.forename: F L
authors.initials: FL
authors.lastname: Musisi
authors.forename: P
authors.initials: P
authors.lastname: Jacobsen
authors.forename: J C
authors.initials: JC
authors.lastname: Quiroga
authors.forename: L M
authors.initials: LM
authors.lastname: Njuguna
mesh_terms: D000818:Animals; D002417:Cattle; D013636:Tanzania; D016797:Theileria parva / Q000145:classification / Q000276:immunology* / Q000302:isolation & purification; D013801:Theileriasis / Q000276:immunology / Q000469:parasitology*; D013987:Ticks / Q000469:parasitology