title: [The effect of low and high molecular weight dextrans on selected lipid parameters in serum. Part 3].
abstract: After a ten-day treatment of 21 patients with low molecular weight dextran (MW = 40,000), a decrease in the plasma concentrations of total cholesterol of 25%, LDL-cholesterol of 32% and apoprotein B of 22% was observed. The HDL fraction only showed a reduction of 10%. These dextran effects were dose-dependent. During the post-treatment period of 20 days a continuous increase in the lipid parameters to the preinfusion values was demonstrated. Dextran caused stronger lipid changes in HLP patients than in normolipaemics.
authors.affiliation: Abteilung Kardiologie/Angiologie, Universität Leipzig.
authors.forename: C
authors.initials: C
authors.lastname: Rühlmann
authors.forename: M
authors.initials: M
authors.lastname: Koksch
authors.forename: K
authors.initials: K
authors.lastname: Hohdorf
authors.forename: B
authors.initials: B
authors.lastname: Kuklinski
mesh_terms: D016632:Apolipoprotein A-I / Q000378:metabolism; D001055:Apolipoproteins B / Q000097:blood; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003911:Dextrans / Q000008:administration & dosage*; D006438:Hemodilution; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000628:therapy*; D007262:Infusions, Intravenous; D008055:Lipids / Q000097:blood*; D008970:Molecular Weight; D014280:Triglycerides / Q000097:blood
chemical_list: D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003911:Dextrans; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol