title: [Stenosing esophagitis in Zollinger-Ellison syndrome].
abstract: Three patients with the Zollinger-Ellison syndrome and severe oesophagitis are reported. Intractable oesophageal stricture developed, leading to oesophago-gastrectomy in two patients and iterative oesophageal dilatations in the third. The retrospective analysis of these 3 cases led us to recommend, in case of oesophagitis in patients who have or might have the Zollinger-Ellison syndrome, to quickly institute a major antisecretory treatment, by parenteral route if necessary, to precociously and repeatedly control the efficacy of the antisecretory treatment mainly by measuring basal acid output and to avoid unjustified treatment discontinuance and gastric intubations.
authors.affiliation: Service d'Hépato-Gastroentérologie, Hôpital Bichat-Claude-Bernard, Paris.
authors.forename: G
authors.initials: G
authors.lastname: Cadiot
authors.forename: C
authors.initials: C
authors.lastname: Hélie
authors.forename: T
authors.initials: T
authors.lastname: Vallot
authors.forename: J P
authors.initials: JP
authors.lastname: Marmuse
authors.forename: J
authors.initials: J
authors.lastname: Cosnes
authors.forename: A
authors.initials: A
authors.lastname: Riché
authors.forename: M
authors.initials: M
authors.lastname: Mignon
mesh_terms: D004940:Esophageal Stenosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D016629:Esophagectomy; D004941:Esophagitis / Q000150:complications* / Q000188:drug therapy; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000627:therapeutic use; D017211:Treatment Failure; D015043:Zollinger-Ellison Syndrome / Q000150:complications*
chemical_list: D009853:Omeprazole