MvaI polymorphism in the proteolipid protein (PLP) gene.
We report a rare polymorphism in the human proteolipid protein (PLP) gene. A synonymous mutation, 168 A-->G, was detected in exon 2 of the PLP gene. Mutations in this gene have been reported in some cases of Pelizaeus-Merzbacher disease.
Osaka
H
H
Department of Pediatrics, School of Medicine, Urafune Hospital of Yokohama City University, Japan.
Inoue
K
K
Kawanishi
C
C
Yamada
Y
Y
Onishi
H
H
Sugiyama
N
N
Suzuki
K
K
Nezu
A
A
Kimura
S
S
Kosaka
K
K
D001483:Base Sequence; D002874:Chromosome Mapping; D017931:DNA Primers / Q000737:chemistry; D015257:DNA-Cytosine Methylases; D005091:Exons / Q000235:genetics; D005787:Gene Frequency; D008040:Genetic Linkage; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011510:Proteolipids / Q000235:genetics*
D017931:DNA Primers; D011510:Proteolipids; C029528:DNA modification methylase EcoRII; D015257:DNA-Cytosine Methylases