title: Synthesis and hypnotic activity of some 2-thioxo-4,5-imidazolidinedione derivatives.
abstract: Several 1-Substituted benzylideneamino-2-thioxo-4,5-imidazolidinedione derivatives were synthesized 2a-i, characterized and evaluated for hypnotic activity. The tested compounds increased the sleeping time to a significant value (p < 0.001).
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Ozkirimli
authors.forename: O
authors.initials: O
authors.lastname: Hamali
mesh_terms: D000818:Animals; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice
chemical_list: D006993:Hypnotics and Sedatives; D007093:Imidazoles