Accidental intra-arterial drug injection successfully treated with Iloprost.
A 35-year-old drug abuser inadvertently injected adulterated heroin into her left femoral artery and presented with critical ischaemia of her left leg. Treatment with intravenous Iloprost, a stable prostacyclin analogue, combined with Heparin, produced a dramatic improvement in her circulation within 4 h.
Samuel
I
I
General Surgical Firm I, St Thomas' Hospital, London, U.K.
Bishop
C C
CC
Jamieson
C W
CW
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D005260:Female; D005263:Femoral Artery / Q000187:drug effects; D006493:Heparin / Q000627:therapeutic use; D003932:Heroin / Q000506:poisoning*; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D007511:Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D007866:Leg / Q000098:blood supply*; D015819:Substance Abuse, Intravenous / Q000150:complications*
D003932:Heroin; D006493:Heparin; D016285:Iloprost