[The epithelial proliferative activity of the mucosa of the large intestine in dysentery patients at the acute period of the disease depending on the expression of morphological changes].
The dependence of proliferative activity on the degree of histomorphological changes in colonic mucosa of patients with dysentery was studied histoautoradiographically in colonic biopsies. Morphological changes were evaluated according to N. B. Shalygina's schema (catarrhal, exudative, erosive or ulcerous inflammation) A 2.5-3-fold increase of the labelled nuclei index (LNI) and label intensity (LI) was found in the catarrhal inflammation. LNI was increased 1.2-fold and LI 1.5-fold in cases of other types of inflammation; they were lower than in catarrhal inflammation.
Borovskaia
T F
TF
Timoshin
S S
SS
Shalygina
N B
NB
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001345:Autoradiography; D001706:Biopsy; D002455:Cell Division; D004405:Dysentery, Bacillary / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D007420:Intestine, Large / Q000473:pathology*; D008297:Male; D012763:Shigella flexneri; D012764:Shigella sonnei