Chromosomal aberrations in cultured human lymphocytes treated with Marshal and its effective ingredient Carbosulfan.
The aim of this study was to investigate the ability of Marshal (insecticide/nematocide) and its effective ingredient Carbosulfan to induce chromosomal aberrations (CA) and other chromosomal abnormalities in human peripheral lymphocytes. Carbosulfan induced the formation of CA at all concentrations (10(-6), 5 x 10(-6), 10(-5), 5 x 10(-5) v/v) and treatment times. Marshal significantly induced the formation of CA at the two highest concentrations (10(-5) and 5 x 10(-5) v/v) at all treatment times. The extent of damage was greatest with Carbosulfan.
Topaktaş
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Cukurova University, Faculty of Arts and Sciences, Department of Biology, Adana, Turkey.
Rencüzoğullar
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E
D000328:Adult; D002219:Carbamates / Q000633:toxicity*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006801:Humans; D066298:In Vitro Techniques; D007306:Insecticides / Q000633:toxicity*; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects*; D008297:Male; D009152:Mutagenicity Tests
D002219:Carbamates; D007306:Insecticides; C035038:carbosulfan