[Measuring skin thickness in perimenopausal women. Correlation with bone density and hormone parameters].
OBJECTIVE
To evaluate the connection between alterations in skin-thickness and bone density in menopause.


METHODS
In 231 perimenopausal women the skin thickness was measured with ultrasound and correlated with the results of bone densitometry and the hormonal parameters.


RESULTS
The correlation between skin thickness and bone densitometry showed a statistical significance of p < 0.0001. Thus we could demonstrate that not only the bone but also the skin is a hormone-dependent organ which responds enormously to a decrease of C19 and C18 steroids.


CONCLUSIONS
Ultrasound skin measurement is a very simple method which can be used for a more differentiated diagnosis and therapy in menopausal women.
Gruber
D
D
Universitätsklinik für Frauenheilkunde Wien.
Sator
M
M
Frigo
P
P
Knogler
W
W
Huber
J C
JC
D015519:Bone Density / Q000502:physiology*; D003937:Diagnosis, Differential; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000097:blood / Q000000981:diagnostic imaging*; D012016:Reference Values; D012867:Skin / Q000000981:diagnostic imaging*; D014463:Ultrasonography
D012739:Gonadal Steroid Hormones