Multiple juvenile xanthogranulomas without foam cells and giant cells.
A 4-month-old boy had numerous nodular lesions. Microscopic findings revealed a histiocytic proliferation without foam cells and giant cells. Immunohistochemical studies showed that the histiocytes belonged to the monocyte-macrophage system and not to the Langerhans cell system. This case is an unusual variant of juvenile xanthogranuloma that, when congenital, may be difficult to differentiate from Hashimoto-Pritzker disease.
Claudy
A L
AL
Department of Dermatology, University Hospital, Hôpital Nord, St Priest en Jarez, France.
Misery
L
L
Serre
D
D
Boucheron
S
S
D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D012867:Skin / Q000473:pathology*; D013194:Staining and Labeling; D014972:Xanthogranuloma, Juvenile / Q000473:pathology*