title: Mer-A2026A and B, novel piericidins with vasodilating effect. I. Producing organism, fermentation, isolation and biological properties.
abstract: A strain of Streptomyces was found to produce new piericidins. The compounds were purified and separated into two substances named Mer-A2026A and B. These new piericidins exhibited vasodilating and depressor activities.
authors.affiliation: Central Research Laboratories, Mercian Corporation, Kanagawa, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kominato
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: S
authors.initials: S
authors.lastname: Hirano
authors.forename: T
authors.initials: T
authors.lastname: Kioka
authors.forename: T
authors.initials: T
authors.lastname: Terasawa
authors.forename: T
authors.initials: T
authors.lastname: Yoshioka
authors.forename: K
authors.initials: K
authors.lastname: Okamura
authors.forename: H
authors.initials: H
authors.lastname: Tone
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D005285:Fermentation; D008297:Male; D011725:Pyridines / Q000302:isolation & purification* / Q000494:pharmacology; D051381:Rats; D011918:Rats, Inbred SHR; D017207:Rats, Sprague-Dawley; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*; D014665:Vasodilator Agents / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000959:Antihypertensive Agents; C092865:Mer A2026A; C092866:Mer A2026B; D011725:Pyridines; D014665:Vasodilator Agents