Steady-state levels of different tenascin mRNAs in various normal human tissues.
Northern blot analysis of TN mRNA from different human tissues shows two major bands of about 6 and 8 kb which correspond to two different mRNAs generated by alternative splicing of the primary transcript. In liver, pancreas and kidney only the 6 kb TN mRNA was detectable. The highest levels of 8 kb TN mRNA were observed in placenta and skin representing 30% and 52% of total TN mRNA, respectively. In all other tissues tested the 8 kb TN mRNA represented less than 20% of total TN mRNA.
Borsi
L
L
Laboratory of Cell Biology, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
Carnemolla
B
B
Ponassi
M
M
Zardi
L
L
D015152:Blotting, Northern; D015816:Cell Adhesion Molecules, Neuronal / Q000032:analysis*; D016326:Extracellular Matrix Proteins / Q000032:analysis*; D006801:Humans; D007668:Kidney / Q000737:chemistry; D008099:Liver / Q000737:chemistry; D008970:Molecular Weight; D010179:Pancreas / Q000737:chemistry; D010920:Placenta / Q000737:chemistry; D012333:RNA, Messenger / Q000032:analysis*; D012867:Skin / Q000737:chemistry; D019063:Tenascin
D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D012333:RNA, Messenger; D019063:Tenascin