title: Effect of human granulocyte colony stimulating factor on neuroblastoma cell growth.
abstract: We have studied the effect of recombinant human granulocyte colony-stimulating factor (G-CSF) on the growth of three different human neuroblastoma (NB) cell lines, using a clonal cell culture and a short proliferation test. The results have shown a lack of effect of G-CSF on the three cell lines. These data promote the use, in clinical trials, of G-CSF as adjunctive treatment in children with NB receiving intensive chemotherapy.
authors.affiliation: CDTS du Val de marne, Henri Mondor Hospital, Créteil, France.
authors.forename: M
authors.initials: M
authors.lastname: Morel
authors.forename: F
authors.initials: F
authors.lastname: Beaujean
authors.forename: C
authors.initials: C
authors.lastname: Le Forestier
authors.forename: O
authors.initials: O
authors.lastname: Hartmann
authors.forename: J
authors.initials: J
authors.lastname: Lemerle
authors.forename: N
authors.initials: N
authors.lastname: Duedari
mesh_terms: D002455:Cell Division / Q000187:drug effects; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D009447:Neuroblastoma / Q000473:pathology*; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014410:Tumor Stem Cell Assay
chemical_list: D016179:Granulocyte Colony-Stimulating Factor