title: Mouse and human chromosomal assignments of mortalin, a novel member of the murine hsp70 family of proteins.
abstract: Mortalin has been shown to exhibit differential distributions in cells with mortal and immortal phenotypes. In the present study, we report mot-2 cDNA cloning from RS-4 cells--an immortal clone from CD1-ICR mouse embryonic fibroblasts--and the chromosomal assignments of mortalin related genes to mouse chromosomes 18 and X by fluorescence in situ hybridization. Similar analysis assigned the gene to chromosome 5q31.1 in human.
authors.affiliation: National Institute of Bioscience and Human Technology, AIST, Ibaraki, Japan.
authors.forename: S C
authors.initials: SC
authors.lastname: Kaul
authors.forename: R
authors.initials: R
authors.lastname: Wadhwa
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuda
authors.forename: P J
authors.initials: PJ
authors.lastname: Hensler
authors.forename: O M
authors.initials: OM
authors.lastname: Pereira-Smith
authors.forename: Y
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Y
authors.initials: Y
authors.lastname: Mitsui
mesh_terms: D000818:Animals; D016466:CHO Cells; D002352:Carrier Proteins; D002460:Cell Line; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D006224:Cricetinae; D004622:Embryo, Mammalian; D005347:Fibroblasts; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics*; D006360:Heat-Shock Proteins / Q000235:genetics*; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008214:Lymphocytes / Q000378:metabolism; D051379:Mice; D008813:Mice, Inbred ICR / Q000235:genetics; D008815:Mice, Inbred Strains / Q000235:genetics*; D024101:Mitochondrial Proteins; D005810:Multigene Family; D014960:X Chromosome
chemical_list: D002352:Carrier Proteins; D018840:HSP70 Heat-Shock Proteins; C492001:HSPA9 protein, human; D006360:Heat-Shock Proteins; C083794:Hspa9 protein, mouse; D024101:Mitochondrial Proteins; C080352:mortalin