title: Bone histomorphometry in 50 normal Tunisian subjects.
abstract: Quantitative bone histomorphometry was done on undecalcified sections of iliac crest bone specimens obtained at autopsy from 50 normal subjects (24 males and 26 females). The following parameters were measured: cortical thickness (Ct.Th), trabecular bone volume (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th), osteoid volume (OV/BV), osteoid surfaces (OS/BS), osteoid thickness (O.Th) and eroded surfaces (ES/BS). There was a significant age-related decrease in BV/TV in both sexes which followed a x3 polynomial regression. A significant decrease of Tb.Th was noted in males after the fifth decade. In males, bone loss was 1.5% per decade, but in females it was 0.36% before menopausal period and 2% after. Other parameters were unrelated to age and sex.
authors.affiliation: Laboratoire d'Histologie Embryologie, Faculté de Médecine, Angers, France.
authors.forename: A
authors.initials: A
authors.lastname: Zhioua
authors.forename: M
authors.initials: M
authors.lastname: Hamdoun
authors.forename: D
authors.initials: D
authors.lastname: Chappard
authors.forename: M F
authors.initials: MF
authors.lastname: Basle
authors.forename: M H
authors.initials: MH
authors.lastname: Jaafoura
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000208:ethnology / Q000473:pathology* / Q000502:physiology; D015519:Bone Density / Q000502:physiology; D001857:Bone Matrix / Q000473:pathology* / Q000648:ultrastructure; D001862:Bone Resorption / Q000473:pathology; D002102:Cadaver; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D007085:Ilium / Q000473:pathology* / Q000502:physiology / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012044:Regression Analysis; D012737:Sex Factors; D014416:Tunisia