title: The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
authors.affiliation: Department of Pharmacology, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Murai
authors.forename: Y
authors.initials: Y
authors.lastname: Maeda
authors.forename: M
authors.initials: M
authors.lastname: Yamaoka
authors.forename: D
authors.initials: D
authors.lastname: Hagiwara
authors.forename: H
authors.initials: H
authors.lastname: Miyake
authors.forename: M
authors.initials: M
authors.lastname: Matsuo
authors.forename: T
authors.initials: T
authors.lastname: Fujii
mesh_terms: D000818:Animals; D016084:Bronchoconstriction / Q000187:drug effects; D002211:Capsaicin / Q000494:pharmacology; D002462:Cell Membrane / Q000378:metabolism; D004151:Dipeptides / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced / Q000503:physiopathology; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D007211:Indoles / Q000494:pharmacology*; D007700:Kinetics; D008168:Lung / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D015288:Neurokinin A / Q000494:pharmacology; D018040:Receptors, Neurokinin-1 / Q000187:drug effects / Q000378:metabolism*; D013373:Substance P / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000494:pharmacology
chemical_list: D004151:Dipeptides; D007211:Indoles; D018040:Receptors, Neurokinin-1; C078949:FK 888; D013373:Substance P; D006632:Histamine; D015288:Neurokinin A; D002211:Capsaicin