title: The unique properties of glutamate receptor channels.
abstract: Rapid excitatory neurotransmission in the central nervous system (CNS) is mediated predominantly by synaptically released L-glutamate which activates cation selective channels with different kinetic and ion conductance properties. Studies with cloned glutamate receptor channels helped delineate the functional properties of channels defined in subunit composition. Moreover, molecular studies have revealed novel genetic mechanisms controlling the expression of important structural channel determinants.
authors.affiliation: Laboratory of Molecular Neuroscience, Heidelberg University, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Sprengel
authors.forename: P H
authors.initials: PH
authors.lastname: Seeburg
mesh_terms: D004553:Electric Conductivity; D007473:Ion Channels / Q000502:physiology*; D007700:Kinetics; D018091:Receptors, AMPA; D017470:Receptors, Glutamate / Q000502:physiology*; D018092:Kainic Acid Receptors; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology
chemical_list: D007473:Ion Channels; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D018092:Kainic Acid Receptors; D016194:Receptors, N-Methyl-D-Aspartate