Pineal ganglioglioma in a patient with familial basal ganglia calcification and elevated serum alpha-fetoprotein: case report.
Pineal ganglioglioma was diagnosed in a 36-year-old man with familial basal ganglia calcification and elevated serum alpha-fetoprotein. The patient was treated surgically with a good result. Only four other cases of this tumor have been reported. His 38-year-old brother also showed basal ganglia calcification and elevated serum chorionic gonadotropin as well as alpha-fetoprotein. Familial basal ganglia calcification with elevated serum alpha-fetoprotein in a nonhepatic benign condition is rare. The pathogenesis of these conditions is discussed.
Tokoro
K
K
Department of Neurosurgery, Kanagawa Rehabilitation Center, Japan.
Chiba
Y
Y
Ohtani
T
T
Abe
H
H
Yagishita
S
S
D000328:Adult; D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D002114:Calcinosis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D018303:Ganglioglioma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D005799:Genes, Dominant / Q000235:genetics; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D010870:Pineal Gland / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins