[The ultrastructure of the neutrophilic leukocytes and alveolar macrophages in chronic lung inflammation and in endobronchial laser irradiation].
310 samples of bronchoalveolar lavage (BAL) from 90 patients with chronic inflammatory processes of lung were studied in the course of endobronchial laser influence. It is shown that considerable quantitative and qualitative changes in cell composition of BAL-fluid resulted from helium-neon laser influence: the percentage increase in macrophage amount, and the decrease in neutrophil number. Using the radioautographic analysis, stimulation of metabolic and proliferative reactions (on the level of RNA and DNA syntheses) of alveolar macrophages under laser influence was found. On the basis of morphological changes of cells in respiratory compartment of lung it is concluded that the clinical effect of laser treatment of chronic inflammatory processes in lung is conditioned by stimulation of regenerative-plastic reactions.
Polosukhin
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D000328:Adult; D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D001999:Bronchoscopy; D002908:Chronic Disease; D005260:Female; D005734:Gangrene / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D053685:Laser Therapy; D008169:Lung Abscess / Q000150:complications / Q000473:pathology / Q000532:radiotherapy; D008262:Macrophage Activation / Q000528:radiation effects; D016676:Macrophages, Alveolar / Q000528:radiation effects* / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000528:radiation effects* / Q000648:ultrastructure*; D011014:Pneumonia / Q000150:complications / Q000473:pathology* / Q000532:radiotherapy*