title: Malignant pancreatic polypeptide secreting tumour of islet cells: a case for aggressive surgical palliation.
abstract: A case of a malignant pancreatic polypeptide secreting tumour is reported. The tumour was metastatic at presentation at which time it was excised. Pancreatic duct obstruction occurred 3 years after excision causing severe pain on eating. Major palliative surgery, in the form of a pancreatico-jejunostomy, cured the severe symptoms. The patient survives, largely symptom free, over six years after original excision. This case illustrates the need for aggressive management of symptoms in tumours in which long term survival is possible despite locally advanced or metastatic disease.
authors.affiliation: Department of Surgery, East Glamorgan General Hospital, Church Village, Mid Glamorgan, Wales.
authors.forename: R D
authors.initials: RD
authors.lastname: Pullan
authors.forename: M W
authors.initials: MW
authors.lastname: Scriven
authors.forename: J
authors.initials: J
authors.lastname: O'Dowd
authors.forename: A T
authors.initials: AT
authors.lastname: Edwards
authors.forename: M H
authors.initials: MH
authors.lastname: Lewis
mesh_terms: D000328:Adult; D018273:Carcinoma, Islet Cell / Q000378:metabolism* / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D010166:Palliative Care; D010190:Pancreatic Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000601:surgery*; D010191:Pancreatic Polypeptide / Q000378:metabolism*; D012086:Reoperation
chemical_list: D010191:Pancreatic Polypeptide