[Occupational extrinsic allergic alveolitis due to Aspergillus oryzae].
We report a case of extrinsic allergic alveolitis, provoked by Deterzyme, a product used in dermatology for the cleaning of cutaneous sores, and containing fractions of protolytic enzymes and amylases of Aspergillus oryzae. The diagnosis was based on the positive precipitins to an extract of antigen of the product as well as positive bronchial provocation tests (semi-delayed) and the disappearance of the symptomatology without any sequelae following cessation of exposure to the risk.
Gueland
C
C
Service de Pneumologie et Immuno-allergologie, Hôpital Albert-Calmette, Lille.
Fruit
J
J
Vannimenus
C
C
Wallaert
B
B
Tonnel
A B
AB
D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced / Q000175:diagnosis*; D000681:Amylases / Q000009:adverse effects*; D001236:Aspergillus oryzae; D001985:Bronchial Provocation Tests; D003880:Dermatology; D010450:Endopeptidases / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D008176:Lung Volume Measurements; D008875:Middle Aged; D009740:Nursing Staff; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis*
C084097:Deterzyme; D000681:Amylases; D010450:Endopeptidases