The effect of lactation on nitric oxide synthase gene expression.
Nitric oxide-synthesizing (NOS) enzyme has been identified in several neural populations, including the hypothalamic paraventricular nucleus (PVN). The PVN plays a major role in regulating milk ejection. In the present study, using in situ hybridization, the effect of lactation on NOS mRNA in the PVN was investigated. A significant increase was seen in the PVN of lactating rats, indicating a possible involvement of nitric oxide in the hypothalamic-pituitary regulation of milk ejection.
Ceccatelli
S
S
Department of Histology and Neurobiology, Karolinska Institute, Stockholm, Sweden.
Eriksson
M
M
D000594:Amino Acid Oxidoreductases / Q000235:genetics*; D000818:Animals; D005260:Female; D015870:Gene Expression / Q000187:drug effects*; D017403:In Situ Hybridization; D007774:Lactation / Q000502:physiology*; D019001:Nitric Oxide Synthase; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D014018:Tissue Distribution
D012333:RNA, Messenger; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases