title: Magnetic resonance imaging in kainic acid-induced limbic seizure status in cats.
abstract: Magnetic resonance imaging before, during, and after kainic acid (KA)-induced limbic seizure status in cats demonstrated the bilateral hippocampi as slightly high-intensity areas on the T2-weighted images during the limbic seizure status, and isointensity areas 1-2 weeks after KA injection when the limbic seizure status subsided. However, the hippocampi again became high-intense 1-3 months after KA injection. Histological study suggested that the high-intensity area during the limbic seizure status resulted from regional edema, and in the chronic period from marked gliosis and/or atrophic change as a consequence of tissue damage in the hippocampus.
authors.affiliation: Department of Neurosurgery, Asahikawa Medical College, Hokkaido.
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Kondo
authors.forename: T
authors.initials: T
authors.lastname: Hori
authors.forename: H
authors.initials: H
authors.lastname: Fukuda
authors.forename: Y
authors.initials: Y
authors.lastname: Yonemasu
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Shindo
mesh_terms: D000679:Amygdala / Q000187:drug effects / Q000473:pathology; D000818:Animals; D002415:Cats; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000139:chemically induced / Q000473:pathology; D017029:Epilepsy, Complex Partial / Q000139:chemically induced* / Q000473:pathology; D006624:Hippocampus / Q000187:drug effects* / Q000473:pathology; D007608:Kainic Acid / Q000494:pharmacology*; D008279:Magnetic Resonance Imaging; D013702:Temporal Lobe / Q000187:drug effects / Q000473:pathology
chemical_list: D007608:Kainic Acid