How to use antibiotics effectively.
Management and control of infectious disease is complicated by a number of variables. This paper reviews factors in choosing an antibiotic; the pharmacokinetic principles of absorption, distribution, metabolism and excretion; duration of therapy; and major causes of failure of antibiotic therapy.
Pallasch
T J
TJ
Pharmacology Section, USC School of Dentistry, Los Angeles, CA 90089.
D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D007769:Lactams; D018942:Macrolides; D009059:Mouth Diseases / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D007769:Lactams; D018942:Macrolides