title: Myopic intrastromal photorefractive keratectomy with the neodymium-yttrium lithium fluoride picosecond laser in the cat cornea.
abstract: OBJECTIVE
  To evaluate the refractive effects of myopic intrastromal photorefractive keratectomy (IPRK) with the neodymium-yttrium lithium fluoride (Nd-YLF) picosecond laser.
  
  
  METHODS
  A 1053-nm Nd-YLF picosecond laser was used to produce myopic IPRK in cat corneas at threshold energy densities. Preoperative corneal topography and ultrasonic pachymetry were performed followed by IPRK in one eye each of 21 cats. No anti-inflammatory medications were administered. Postoperative corneal topography, ultrasonic pachymetry, and slit-lamp examination were performed at scheduled intervals.
  
  
  RESULTS
  An average topographic flattening of 11.4 diopters and pachymetric thinning of 50 microns at the center of the treatment zone were observed by 6 weeks following treatment. The average diameter of the zone of flattening was 5.1 mm at 6 weeks and 6.0 mm at 12 weeks postoperatively. At 6 months postoperatively, the average central corneal power was unchanged, while the average central thickness had returned to the preoperative value. A mild subepithelial haze was detected at 1 month following IPRK, which was barely perceptible at the second through sixth months. Regression of the topographic effects of PRK was not observed.
  
  
  CONCLUSIONS
  Intrastromal PRK with the Nd-YLF picosecond laser produces central flattening of the cat cornea with barely perceptible stromal haze and no regression of topographic effect after 6 months in the absence of treatment with anti-inflammatory agents.
authors.affiliation: Department of Ophthalmology, New York Eye and Ear Infirmary, New York, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Habib
authors.forename: M G
authors.initials: MG
authors.lastname: Speaker
authors.forename: R
authors.initials: R
authors.lastname: Kaiser
authors.forename: T
authors.initials: T
authors.lastname: Juhasz
mesh_terms: D000818:Animals; D002415:Cats; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003319:Corneal Stroma / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D007091:Image Processing, Computer-Assisted; D053685:Laser Therapy; D009216:Myopia / Q000473:pathology / Q000601:surgery*