Trimeric C-type lectin domains in host defence.
Recent crystal structures, established for fragments of human and rat mannose-binding proteins, indicate that the triple-stranded alpha-helical coiled coil present in these collectins is responsible for the trimeric orientation of C-type lectin domains.
Hoppe
H J
HJ
Department of Biochemistry, University of Oxford, UK.
Reid
K B
KB
D000595:Amino Acid Sequence; D000818:Animals; D018360:Crystallography, X-Ray; D006801:Humans; D037102:Lectins / Q000737:chemistry*; D008969:Molecular Sequence Data; D011487:Protein Conformation
D037102:Lectins