Recent results on functional polymers and macromonomers of interest as biomaterials or for biomaterial modification.
Different families of functionalized polymers with potential as biomaterials, or for biomaterial modification, have been investigated. In particular, degradation studies have been performed on poly(amidoamines), a family of polymers obtained by polyaddition of amines to bisacrylamides, and endowed with heparin-complexing ability. Some new poly(amidoamines) with more resistance towards hydrolytic degradation than traditional ones have been discovered. Other ter-amino polymers deriving from the polyaddition of ter-amino functionalized bis-thiols to bis-acrylic esters, or other activated unsaturated compounds, have been studied. Their quaternarization products have been proven, in a parallel work, to act as powerful antimicrobial agents. By performing in situ the polyaddition reaction, semi-interpenetrated networks based on silicone rubber and the same polymers have been prepared. Finally, end-functionalized amphiphilic oligomers have been prepared by radical polymerization techniques, and their use for enzyme modification considered.
Ferruti
P
P
Dipartimento di Chimica e Fisica per i Materiali, Università di Brescia, Italy.
Ranucci
E
E
Sartore
L
L
Bignotti
F
F
Marchisio
M A
MA
Bianciardi
P
P
Veronese
F M
FM
D001672:Biocompatible Materials / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*
D001672:Biocompatible Materials; D011073:Polyamines; D011108:Polymers