[Study on the relationship between hormonal cytology and bone mineral density in postmenopausal women].
We assessed the relationship between bone mineral density (BMD) and hormonal cytology in 181 postmenopausal women. BMD was measured by dual energy X-ray absorptiometry (DXA). Age, height, weight, body mass index (BMI), age at menopause, hormonal cytology (eosinophilic index (EI), karyopyknotic index (KPI) and maturation value (MV)) and estradiol were investigated. A positive correlation was found between BMD and hormonal cytology (EI r = 0.17 p < 0.05, KPI r = 0.19 p < 0.05 and MV r = 0.37 p < 0.005). The low BMD group (BMD < 0.8g/cm2 n = 87) had significantly lower hormonal cytology than the normal BMD group (BMD > or = 0.8g/cm2 n = 94). The receiver operating characteristic curve analysis showed MV at 30 was available for the cutoff point in predicting osteopenia. MV < 30 detected osteopenia (BMD < 0.8g/cm2) as 0.76 in sensitivity and 0.65 in specificity. These findings suggest that hormonal cytology is useful for screening osteopenia in post-menopausal women.
Yasuda
M
M
Department of Obstetrics and Gynecology, Niigata University School of Medicine.
Kurabayashi
T
T
Yamamoto
Y
Y
Fujimaki
T
T
Oda
K
K
Minagawa
Y
Y
Kodama
S
S
Tanaka
K
K
D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D015519:Bone Density; D003581:Cytodiagnosis / Q000379:methods; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D004958:Estradiol