Neurogenic inflammation in the chicken (Gallus gallus var domesticus).
1. Neurogenic inflammation has been studied in the anaesthetized adult hen using a variety of different stimuli. 2. Plasma extravasation was produced following antidromic stimulation of the external mandibular ramus of the trigeminal nerve which innervates the skin at the angle of the jaw and the anterior part of the wattle. 3. Stimulation of the wattle by external application of mustard oil, thermal and mechanical stimuli, as well as intradermal injection of substance P and bradykinin, all produced plasma extravasation. 4. These results demonstrate that, in contrast to previous findings in the pigeon, at least in the trigeminal of the chicken peripheral C-fibre nociceptors have similar physiological characteristics in relation to the neurogenic inflammatory mechanism to those seen in mammals.
Gentle
M J
MJ
AFRC Institute of Animal Physiology and Genetics Research, Roslin, Midlothian, U.K.
Hunter
L N
LN
D000758:Anesthesia; D000818:Animals; D001920:Bradykinin; D002645:Chickens; D003129:Comb and Wattles / Q000502:physiology; D004558:Electric Stimulation; D005070:Evans Blue; D005260:Female; D006358:Hot Temperature; D017879:Isothiocyanates; D009412:Nerve Fibers / Q000187:drug effects / Q000502:physiology; D009443:Neuritis / Q000139:chemically induced / Q000473:pathology*; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology; D010812:Physical Stimulation; D012879:Skin Physiological Phenomena; D013373:Substance P; D014276:Trigeminal Nerve / Q000473:pathology
D017879:Isothiocyanates; D013373:Substance P; D005070:Evans Blue; C004471:allyl isothiocyanate; D001920:Bradykinin