[Autoantibodies against podocytes of the kidney glomerulus].
Novel autoantibodies are described which react with renal podocytes. These antibodies were found in 9 patients (2 with renal disease, 2 with liver disease, 2 with rheumatic disease, 1 with achalasia, 1 with carcinoma of the pancreas and 1 with anemia). Colocalization studies with double immunofluorescence and confocal laser scanning microscopy using monoclonal antibodies against the 44 kD podocyte protein showed a similar fluorescence pattern for both antibodies. The target antigens remain unclear.
Storch
W B
WB
Gemeinschaftspraxis für Labormedizin, Mönchengladbach.
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007678:Kidney Glomerulus / Q000166:cytology / Q000276:immunology*; D008875:Middle Aged
D001323:Autoantibodies