Dosimetry of high energy electron therapy to the parotid region.
Well-known inadequacies in currently available electron planning systems, and two cases of temporal lobe necrosis following electron therapy of the parotid stimulated a comprehensive head and neck phantom dosimetric study of the use of high energy electrons for parotid treatments. A typical electron field employed for the treatment of parotid malignancy was examined in an anthropomorphic head phantom from which air cavities had been excavated. Thermoluminescent dosimeter measurements were compared with predicted point doses obtained from a Theraplan Treatment planning system (V05). Data was examined for three different electron energies: 12, 16 and 20 MeV and with the addition of contoured bolus for 20 MeV. A number of significant discrepancies between the measured and predicted dose were observed. Measured doses were seen to exceed predicted doses by up to 23% in the temporal lobe. Further under-predictions of dose were found behind the mandible and in the nasal cavity. Over-predictions of dose by the planning algorithm of up to 22% were observed beside the oropharynx. Some of these discrepancies were found to relate to Theraplan under-estimation of the dose in the fall-off region. Other errors are attributable to the difficulties in predicting dose at density interfaces. Localised over- and under-predictions of this magnitude must be accounted for by the clinician prescribing treatment in terms of possible late effects on the temporal lobe and, in particular, the nominated dose specification point.
Ostwald
P M
PM
Department of Radiation Oncology, Newcastle Mater Misericordiae Hospital, Waratah, NSW, Australia.
Cooper
S G
SG
Denham
J W
JW
Hamilton
C S
CS
D000231:Adenocarcinoma, Papillary / Q000532:radiotherapy*; D000328:Adult; D000368:Aged; D000465:Algorithms; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D005260:Female; D006257:Head / Q000033:anatomy & histology / Q000528:radiation effects; D006801:Humans; D008297:Male; D008961:Models, Structural; D009336:Necrosis; D010307:Parotid Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011882:Radiotherapy, High-Energy / Q000009:adverse effects; D013702:Temporal Lobe / Q000473:pathology / Q000528:radiation effects*