title: Determination of creatinine in human serum. Statistical intercalibration of methods.
abstract: An intercalibration of methods was performed in the determination of creatinine in human plasma. Jaffè, enzymatic creatinine-deaminase (CRDI) and ion-interaction reagent high-performance liquid chromatography (HPLC) methods were employed and the results were compared using a parametric t-test for multiple samples and non-parametric Mann-Whitney, Wilcoxon and Friedman tests. The comparison did not show a statistically significant difference in the use of the three methods. The ion-interaction HPLC procedure is proposed as a reference method for creatinine assays.
authors.affiliation: Dipartimento di Chimica Analitica, Università di Torino, Turin, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Gennaro
authors.forename: C
authors.initials: C
authors.lastname: Abrigo
authors.forename: E
authors.initials: E
authors.lastname: Marengo
authors.forename: C
authors.initials: C
authors.lastname: Baldin
authors.forename: M T
authors.initials: MT
authors.lastname: Martelletti
mesh_terms: D002138:Calibration; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003404:Creatinine / Q000097:blood*; D004563:Electrochemistry; D006801:Humans; D013056:Spectrophotometry, Ultraviolet; D013223:Statistics as Topic
chemical_list: D003404:Creatinine