title: Hemangioblastoma of the radial nerve: case report.
abstract: A case of hemangioblastoma of the right radial nerve is presented. Hemangioblastomas are rare vascular neoplasms characteristically associated with the Von Hippel-Lindau syndrome, in which they are found in the retina, the posterior fossa, and, less often, the spinal cord. Thought of as primary central nervous system neoplasms, hemangioblastomas are rarely found adjacent to the spinal cord involving proximal nerve roots, which represent border zones between the central and peripheral nervous systems. We could find no other report of a pure hemangioblastoma situated this far distally in the peripheral nervous system. The histological findings, immunohistochemistry, and electron microscopic findings of this lesion are discussed. This case supports the hypothesis that hemangioblastoma is not derived from astrocytes, because of the location of this tumor in the peripheral nervous system and glial fibrillary acidic protein negativity.
authors.affiliation: Department of Neurosurgery, University of Tennessee, College of Medicine, Memphis.
authors.forename: J A
authors.initials: JA
authors.lastname: Brodkey
authors.forename: J A
authors.initials: JA
authors.lastname: Buchignani
authors.forename: T F
authors.initials: TF
authors.lastname: O'Brien
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D018325:Hemangioblastoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008854:Microscopy, Electron; D009460:Neurologic Examination; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D011826:Radial Nerve / Q000473:pathology / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein