title: Differential localization of mRNAs encoding dopamine D1 or D2 receptors in cholinergic neurons in the core and shell of the rat nucleus accumbens.
abstract: By combining immunocytochemistry for ChAT and in situ hybridization for dopamine D1 or D2 receptor mRNA in the striatum, it was found that (1) the percentage of ChAT/D2 mRNA co-localization is higher in the caudate-putamen than in the shell and core of the nucleus accumbens, (2) in the shell the degree of ChAT/D2 mRNA co-localization is higher rostrally than caudally, and 3) no significant regional differences exist in the degree of co-localization of ChAT and D1 mRNA.
authors.affiliation: Graduate School of Neurosciences Amsterdam, Vrije Universiteit, Faculty of Medicine, Department of Anatomy and Embryology, The Netherlands.
authors.forename: A L
authors.initials: AL
authors.lastname: Jongen-Rêlo
authors.forename: G J
authors.initials: GJ
authors.lastname: Docter
authors.forename: A J
authors.initials: AJ
authors.lastname: Jonker
authors.forename: P
authors.initials: P
authors.lastname: Voorn
mesh_terms: D000818:Animals; D001479:Basal Ganglia / Q000378:metabolism*; D002421:Caudate Nucleus / Q000378:metabolism; D003342:Corpus Striatum / Q000378:metabolism*; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D009714:Nucleus Accumbens / Q000737:chemistry* / Q000378:metabolism; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics*; D051381:Rats; D017447:Receptors, Dopamine D1 / Q000096:biosynthesis / Q000378:metabolism*; D017448:Receptors, Dopamine D2 / Q000096:biosynthesis / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger; D017447:Receptors, Dopamine D1; D017448:Receptors, Dopamine D2