Prevalence of human astrovirus serotype 4: capsid protein sequence and comparison with other strains.
Astrovirus serotype 4 has increased in relative prevalence in the Oxford, UK area in 1993. The structural gene of human astrovirus serotype 4 has been sequenced and the results indicate that this protein differs substantially from serotypes 1 and 2. In particular, conservation at the C terminus is greatly reduced. However, amino acid substitutions in this region show a strong conservation in character suggesting that structural or functional constraints operate in this region.
Willcocks
M M
MM
School of Biological Sciences, University of Surrey, Guildford, UK.
Kurtz
J B
JB
Lee
T W
TW
Carter
M J
MJ
D000595:Amino Acid Sequence; D001483:Base Sequence; D002213:Capsid / Q000737:chemistry* / Q000235:genetics; D005814:Genes, Viral; D006801:Humans; D001257:Mamastrovirus / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012703:Serotyping; D015678:Viral Structural Proteins / Q000235:genetics
D015678:Viral Structural Proteins