title: Induction of adipose conversion in 3T3-L1 cells is associated with an early phosphorylation of a protein partly homologous with mouse vimentin.
abstract: Induction of adipose conversion in 3T3-L1 by bezafibrate has been previously shown to be enhanced by dibutyryl cAMP and to be associated with an early phosphorylation of a 60 kDa acidic protein [Biochim. Biophys. Acta 1054 (1990) 219-224; FEBS Lett. 285 (1991) 63-65]. We describe here the isolation and sequencing of two peptides of the protein concerned. Both appear to be homologous with two respective amino acid sequences of the mouse intermediate filament protein vimentin.
authors.affiliation: Department of Human Nutrition and Metabolism, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Brandes
authors.forename: R
authors.initials: R
authors.lastname: Arad
authors.forename: A
authors.initials: A
authors.lastname: Gaathon
authors.forename: J
authors.initials: J
authors.lastname: Bar-Tana
mesh_terms: D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D016475:3T3 Cells; D017667:Adipocytes / Q000378:metabolism*; D000595:Amino Acid Sequence; D000818:Animals; D001629:Bezafibrate / Q000494:pharmacology; D003994:Bucladesine / Q000494:pharmacology; D002454:Cell Differentiation / Q000502:physiology; D015180:Electrophoresis, Gel, Two-Dimensional; D015151:Immunoblotting; D051379:Mice; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010446:Peptide Fragments / Q000737:chemistry; D010766:Phosphorylation; D017386:Sequence Homology, Amino Acid; D014746:Vimentin / Q000737:chemistry / Q000378:metabolism*
chemical_list: D010446:Peptide Fragments; D014746:Vimentin; D003994:Bucladesine; D015056:1-Methyl-3-isobutylxanthine; D001629:Bezafibrate