[Immunoblotting analysis of acquired factor VIII inhibitor in an elderly man].
A case of acquired FVIII inhibitor in a nonhemophilic, 80 year-old man who had no underlying disorder, is presented. The level of inhibitor was 13.3 Bethesda unit/ml, and the antibody was IgG, with lambda light chain. The antibody reacted with the 92 kD fragment of non-treated human FVIII, and the 44 kD fragment of thrombin treated FVIII when analysed by the immunoblot analysis.
Kikuchi
M
M
Department of Internal Medicine, Saga Medical School.
Sano
M
M
Shimamoto
Y
Y
Yamaguchi
M
M
Tadano
J
J
Takahashi
I
I
Kamiya
T
T
D000368:Aged; D000369:Aged, 80 and over; D000906:Antibodies / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D008297:Male
D000906:Antibodies; D000939:Epitopes; D005169:Factor VIII