title: Mesonephric adenocarcinoma of the uterine cervix with focal endocrine cell differentiation.
abstract: A case of cervical adenocarcinoma arising in diffuse mesonephric hyperplasia is presented. The hyperplastic and neoplastic tubules showed focal endocrine cell differentiation. Endocrine cells stained with the Grimelius technique, and were immunoreactive for chromogranin and serotonin. Antisera to additional specific hormones were negative. The natural history of this rare tumor is uncertain; the patient presented in this report is free of disease at 10-year follow-up.
authors.affiliation: Department of Cytology, Glasgow Royal Infirmary, Scotland.
authors.forename: C J
authors.initials: CJ
authors.lastname: Stewart
authors.forename: C R
authors.initials: CR
authors.lastname: Taggart
authors.forename: F
authors.initials: F
authors.lastname: Brett
authors.forename: A F
authors.initials: AF
authors.lastname: Mutch
mesh_terms: D000328:Adult; D002454:Cell Differentiation; D002584:Cervix Uteri / Q000473:pathology; D002864:Chromogranins / Q000032:analysis; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D008649:Mesonephroma / Q000473:pathology* / Q000601:surgery; D012701:Serotonin / Q000032:analysis; D013194:Staining and Labeling; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014599:Uterus / Q000473:pathology; D014746:Vimentin / Q000032:analysis
chemical_list: D002864:Chromogranins; D014746:Vimentin; D012701:Serotonin; D007633:Keratins