title: Signal transduction, mitotic catastrophes, and death in T-cell development.
authors.affiliation: Amgen Institute, University of Toronto, Ontario, Canada.
authors.forename: J M
authors.initials: JM
authors.lastname: Penninger
authors.forename: T W
authors.initials: TW
authors.lastname: Mak
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D015551:Autoimmunity / Q000502:physiology; D017637:Clonal Deletion / Q000276:immunology; D004268:DNA-Binding Proteins / Q000502:physiology; D005938:Glucocorticoids / Q000494:pharmacology; D006801:Humans; D050856:Interferon Regulatory Factor-1; D017493:Leukocyte Common Antigens / Q000502:physiology; D008938:Mitosis / Q000502:physiology*; D010750:Phosphoproteins / Q000502:physiology; D010802:Phylogeny; D011505:Protein-Tyrosine Kinases / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000502:physiology; D019253:Proto-Oncogene Proteins c-bcl-2; D018124:Receptors, Tumor Necrosis Factor / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D013601:T-Lymphocytes / Q000502:physiology*; D013950:Thymus Gland / Q000187:drug effects
chemical_list: D004268:DNA-Binding Proteins; D005938:Glucocorticoids; C494257:IRF1 protein, human; D050856:Interferon Regulatory Factor-1; D010750:Phosphoproteins; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D018124:Receptors, Tumor Necrosis Factor; D011505:Protein-Tyrosine Kinases; D017493:Leukocyte Common Antigens