Intra-arterial administration of adriamycin-loaded albumin microspheres for locally advanced breast cancer.
Regional chemotherapy is an attractive but underevaluated method of treating locally advanced breast cancer. We have combined two novel methods of targeting by delivering a single pulse of adriamycin-loaded albumin microspheres down a radiologically placed internal mammary artery catheter. A complete response was observed and prolonged local control achieved.
Doughty
J C
JC
University Department of Surgery, Royal Infirmary, Glasgow, UK.
Anderson
J H
JH
Willmott
N
N
McArdle
C S
CS
D000328:Adult; D000418:Albumins; D001943:Breast Neoplasms / Q000188:drug therapy*; D002406:Catheterization, Peripheral; D004317:Doxorubicin / Q000008:administration & dosage*; D016503:Drug Delivery Systems / Q000379:methods*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008863:Microspheres
D000418:Albumins; D004317:Doxorubicin