title: Bulbospinal augmenting inspiratory neurons may participate in contractions of the diaphragm during vomiting in decerebrate dogs.
abstract: Contradictory results have been reported regarding the participation of bulbospinal inspiratory (BSI) neurons in vomiting contractions of the diaphragm in dogs and cats maintained at low and high end-tidal CO2 levels, respectively. To resolve this discrepancy, effects of CO2 levels on vomiting activities were observed in 159 BSI-neurons of paralyzed decerebrate dogs. About half of the BSI-neurons exhibited a vigorous burst with each fictive retch regardless of the CO2 level and 28 of 51 BSI-neurons produced a burst during the early phase of expulsion. These BSI-neurons were not concentrated in any particular area. While these results do not resolve the above contradiction, they do suggest that some BSI-neurons participate in the vomiting contraction of the diaphragm.
authors.affiliation: Department of Physiology, Kawasaki Medical School, Kurashiki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Koga
authors.forename: H
authors.initials: H
authors.lastname: Fukuda
mesh_terms: D000009:Abdominal Muscles / Q000294:innervation / Q000503:physiopathology; D000200:Action Potentials; D000818:Animals; D001933:Brain Stem / Q000503:physiopathology*; D002245:Carbon Dioxide / Q000097:blood; D003655:Decerebrate State / Q000503:physiopathology*; D003964:Diaphragm / Q000294:innervation / Q000503:physiopathology*; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D001239:Inhalation / Q000502:physiology; D008297:Male; D009119:Muscle Contraction; D009476:Neurons, Efferent / Q000502:physiology*; D010791:Phrenic Nerve / Q000503:physiopathology; D013116:Spinal Cord / Q000503:physiopathology*; D014630:Vagus Nerve / Q000503:physiopathology; D014839:Vomiting / Q000503:physiopathology*
chemical_list: D002245:Carbon Dioxide