Beneficial effects of dextro-amphetamine in the treatment of vasodepressor syncope.
Three patients with history of documented hypotension, near syncope, or syncope before or after the administration of isoproterenol during head-up tilt table are reported. Severe bradycardia was also noted in one patient. All three patients responded to the administration of 2.5 mg of oral dextroamphetamine 45 minutes prior to a repeat head-up tilt table study. The potent central and peripheral adrenergic agonist pharmacological properties of this drug permitted the prevention of severe vasodepressor syncope in these patients.
Susmano
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A
Department of Medicine, Rush-Presbyterian St. Luke's Medical Center, Chicago, Illinois.
Volgman
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AS
Buckingham
T A
TA
D000368:Aged; D001919:Bradycardia / Q000150:complications / Q000188:drug therapy*; D003913:Dextroamphetamine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011187:Posture / Q000502:physiology; D013575:Syncope / Q000188:drug therapy* / Q000209:etiology
D003913:Dextroamphetamine