Menkes' kinky-hair disease: radiologic findings in a patient treated with copper histidinate.
A patient with Menkes' kinky-hair disease was treated from an early age with copper histidinate. This patient did not display the progressive mental deterioration and early death typical of patients with Menkes' disease; on the contrary, his intellectual capabilities were above average for his age. The magnetic resonance imaging findings were unique, showing some tortuosity and elongation of the arteries but no evidence of cerebral atrophy, demyelination or subdural hygromas.
Waslen
T A
TA
Royal University Hospital, Saskatoon, Sask.
Houston
C S
CS
Tchang
S
S
D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D005500:Follow-Up Studies; D006639:Histidine / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000473:pathology; D009942:Organometallic Compounds / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D009942:Organometallic Compounds; C045576:copper bis(histidinate); D006639:Histidine