title: A selective and extremely potent antagonist of the neurokinin-1 receptor.
authors.affiliation: Department of Pharmacology, Tohoku College of Pharmacy, Sendai, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sakurada
authors.forename: Y
authors.initials: Y
authors.lastname: Manome
authors.forename: K
authors.initials: K
authors.lastname: Tan-No
authors.forename: S
authors.initials: S
authors.lastname: Sakurada
authors.forename: M
authors.initials: M
authors.lastname: Ohba
authors.forename: K
authors.initials: K
authors.lastname: Kisara
authors.forename: L
authors.initials: L
authors.lastname: Terenius
mesh_terms: D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D002462:Cell Membrane / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007278:Injections, Spinal; D007700:Kinetics; D051379:Mice; D064729:Neurokinin-1 Receptor Antagonists; D010446:Peptide Fragments / Q000008:administration & dosage / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D018040:Receptors, Neurokinin-1 / Q000502:physiology; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D013373:Substance P / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D064729:Neurokinin-1 Receptor Antagonists; D010446:Peptide Fragments; D018040:Receptors, Neurokinin-1; D013373:Substance P; C032292:substance P (6-11); D011761:Pyrrolidonecarboxylic Acid