title: Magnetic resonance imaging and computed tomography features of nasopharyngeal carcinoma with maxillary sinus involvement.
abstract: Anterior spread of nasopharyngeal carcinoma (NPC) may infiltrate the maxillary sinus. In a prospective study of 114 patients comparing magnetic resonance imaging (MRI) and computed tomography (CT) in the staging of NPC, 10 (9%) patients were noted to have tumour infiltration of the maxillary sinuses. All of the patients except one had associated infiltration of the sphenoidal sinuses indicating advanced local spread. Computed tomography was excellent in outlining the extent of bony erosion and associated soft tissue mass within the antra. T1-weighted images could not demonstrate bony erosions directly although soft tissue extension into the sinuses could be clearly visualized. Both CT and MRI showed good demarcation between tumour and mucosal thickening within the maxillary sinus. Although MRI demonstrated soft tissue involvement more elegantly than CT, it did not appear to offer significantly more information that may affect clinical management.
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital.
authors.forename: V F
authors.initials: VF
authors.lastname: Chong
authors.forename: Y F
authors.initials: YF
authors.lastname: Fan
authors.forename: K H
authors.initials: KH
authors.lastname: Toh
authors.forename: J B
authors.initials: JB
authors.lastname: Khoo
authors.forename: T A
authors.initials: TA
authors.lastname: Lim
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008279:Magnetic Resonance Imaging; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009361:Neoplasm Invasiveness; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D007472:Iohexol; C038192:iopromide; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA