title: Squamous differentiation in malignant eccrine poroma.
abstract: Squamous differentiation in poral adnexal neoplasms is a rare event. Two cases are presented of malignant eccrine poroma in which areas of squamous differentiation showing the features of squamous cell carcinoma were present. The areas of squamous differentiation were found within the invasive components of the lesions and appeared to result from direct transformation of the poral epithelial cells. A review of the literature on this unusual phenomenon is presented.
authors.affiliation: Arkadi M. Rywlin Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140.
authors.forename: J
authors.initials: J
authors.lastname: Peña
authors.forename: S
authors.initials: S
authors.lastname: Suster
mesh_terms: D018250:Acrospiroma / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003593:Cytoplasm / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005534:Foot Diseases / Q000473:pathology; D006801:Humans; D006818:Hyalin; D015603:Keratinocytes / Q000473:pathology; D007633:Keratins; D008297:Male; D009361:Neoplasm Invasiveness; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D013848:Thigh
chemical_list: C001500:keratohyalin; D007633:Keratins