Transcriptional activation. Tuning-up transcription.
Eukaryotic transcription is a complex process, and recent results identify multiple steps that need to be stimulated to activate transcription, one of which is a change in conformation of the general transcription factor TFIIB.
Sheldon
M
M
Howard Hughes Medical Institute, Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854-5635.
Reinberg
D
D
D000818:Animals; D004268:DNA-Binding Proteins / Q000378:metabolism; D006801:Humans; D012319:RNA Polymerase II / Q000378:metabolism; D035181:TATA-Box Binding Protein; D035581:Transcription Factor TFIIB; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic
D004268:DNA-Binding Proteins; D035181:TATA-Box Binding Protein; D035581:Transcription Factor TFIIB; D014157:Transcription Factors; D012319:RNA Polymerase II