[Hematopoietic growth factors as supportive treatment in drug-induced agranulocytosis].
This article describes the use of granulocyte macrophage colony stimulating factor and granulocyte colony stimulating factor in two patients with drug induced granulocytopenia. A granulocyte count > 1 x 10(9)/l was obtained after 7 days' treatment. These results suggest that the haematopoietic growth factors shortened the period of agranulocytosis and subsequently may improve the survival of these patients.
Hospers
G A
GA
Afd. Hematologie, Academisch Ziekenhuis, Groningen.
de Wolf
J T
JT
Hazenberg
B P
BP
Vellenga
E
E
D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced* / Q000188:drug therapy*; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged
D000893:Anti-Inflammatory Agents; D016179:Granulocyte Colony-Stimulating Factor; D016178:Granulocyte-Macrophage Colony-Stimulating Factor