Diffuse Lewy body disease as substrate of primary lateral sclerosis.
We describe the case of a 40-year-old male patient who had presented clinically as primary lateral sclerosis for the past 10 years and neuropathologically as diffuse Lewy body disease (DLBD). Neuropathology demonstrated DLBD as an almost ubiquitous disorder of the neuronal cytoskeleton.
Hainfellner
J A
JA
Clinical Institute of Neurology, AKH, Vienna, Austria.
Pilz
P
P
Lassmann
H
H
Ladurner
G
G
Budka
H
H
D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000209:etiology / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D016631:Lewy Bodies / Q000648:ultrastructure; D008297:Male; D016900:Neurofilament Proteins / Q000032:analysis; D010300:Parkinson Disease / Q000150:complications / Q000473:pathology*; D014452:Ubiquitins / Q000032:analysis; D016875:tau Proteins / Q000032:analysis
D016900:Neurofilament Proteins; D014452:Ubiquitins; D016875:tau Proteins