title: Prevention of fatal pulmonary embolism.
abstract: Venous thromboembolism is a frequent complication in hospitalized patients. A number of drugs are now available to prevent this complication. These include dextron, oral anticoagulants, standard heparin and low-molecular-weight heparin. The efficacy of these drugs is reviewed in this paper. The data presented indicate that a single fixed daily subcutaneous injection of low-molecular-weight heparin provides a simple and an effective method of preventing death due to massive pulmonary embolism. Therefore emphasis should now be on the physicians and surgeons to protect all high-risk patients.
authors.affiliation: Thrombosis Research Institute, London, UK.
authors.forename: V V
authors.initials: VV
authors.lastname: Kakkar
mesh_terms: D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D003911:Dextrans / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications / Q000188:drug therapy / Q000401:mortality / Q000517:prevention & control*; D011446:Prospective Studies; D011655:Pulmonary Embolism / Q000401:mortality / Q000517:prevention & control*; D012306:Risk; D013924:Thrombophlebitis / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D003911:Dextrans; D006495:Heparin, Low-Molecular-Weight; D006493:Heparin