title: Vibration stimulus induced EEG bursts in isoflurane anaesthesia.
abstract: The EEG and heart rate reactions to vibration stimulus were studied in 14 patients during moderately deep surgical isoflurane anaesthesia, at a level when EEG showed a burst suppression pattern. Vibration applied to the palm of the hand induced bursts in EEG in 12 patients, usually with a latency of about 0.5 sec from the onset, or from the end of the 3 sec stimulus. Increases in heart rate were seen at bursts related to both vibration onset and offset, as well as at spontaneous bursts. With spontaneous bursts, an initial positive wave was frequently seen. In 6 patients the vibration induced bursts were different in shape from the spontaneous bursts; no initial positive wave was seen before the negative DC shift in Cz-Fz recording. We conclude that EEG bursts can be evoked by a non-noxious stimulus such as vibration in patients during isoflurane anaesthesia.
authors.affiliation: Department of Anaesthesiology, Helsinki University Central Hospital, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Yli-Hankala
authors.forename: V
authors.initials: V
authors.lastname: Jäntti
authors.forename: I
authors.initials: I
authors.lastname: Pyykkö
authors.forename: L
authors.initials: L
authors.lastname: Lindgren
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007530:Isoflurane; D008297:Male; D008875:Middle Aged; D010812:Physical Stimulation; D014732:Vibration
chemical_list: D007530:Isoflurane