title: Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion.
authors.affiliation: Drug Discovery Division, R.W. Johnson Pharmaceutical Research Institute, Spring House, Pennsylvania 19477, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Sanfilippo
authors.forename: M C
authors.initials: MC
authors.lastname: Jetter
authors.forename: R
authors.initials: R
authors.lastname: Cordova
authors.forename: R A
authors.initials: RA
authors.lastname: Noe
authors.forename: E
authors.initials: E
authors.lastname: Chourmouzis
authors.forename: C Y
authors.initials: CY
authors.lastname: Lau
authors.forename: E
authors.initials: E
authors.lastname: Wang
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000517:prevention & control; D066298:In Vitro Techniques; D018799:Intercellular Adhesion Molecule-1 / Q000737:chemistry*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000737:chemistry*; D051379:Mice; D011720:Pyrazoles / Q000494:pharmacology*; D013844:Thiazoles / Q000737:chemistry / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D016169:Lymphocyte Function-Associated Antigen-1; D011720:Pyrazoles; C092963:RWJ 50271; D013844:Thiazoles; D018799:Intercellular Adhesion Molecule-1