title: N-methyl-N-nitrosourea evidences cell cycle associated transient sequences in hepatic replicating DNA.
abstract: Experiments of molecular hybridization were carried out with the aim of singling out DNA sequences which might be important in the hepatocarcinogenic action of N-methyl-N-nitrosourea. Results were obtained suggesting the synthesis of transitory DNA sequences during compensatory cell proliferation.
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Science, University of Bari, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Kanduc
mesh_terms: D000818:Animals; D002453:Cell Cycle / Q000187:drug effects*; D004247:DNA / Q000378:metabolism; D004261:DNA Replication / Q000187:drug effects*; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D008745:Methylation; D008770:Methylnitrosourea / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008770:Methylnitrosourea; D004247:DNA