title: Production of prostatic lesions in canines using transrectally administered high-intensity focused ultrasound.
abstract: High-intensity focused ultrasound is a method of destroying tissue at a point distant from the transducer without injuring intervening tissue. A transrectal probe was developed and used to treat 26 canines in order to determine the feasibility of using this therapy in humans. Lesions of coagulative necrosis which evolved into cystic cavities were produced. Surrounding tissue was preserved without evidence of injury.
authors.affiliation: Department of Urology, Indiana University Medical Center, Indianapolis 46202-5250.
authors.forename: R S
authors.initials: RS
authors.lastname: Foster
authors.forename: R
authors.initials: R
authors.lastname: Bihrle
authors.forename: N
authors.initials: N
authors.lastname: Sanghvi
authors.forename: F
authors.initials: F
authors.lastname: Fry
authors.forename: K
authors.initials: K
authors.lastname: Kopecky
authors.forename: J
authors.initials: J
authors.lastname: Regan
authors.forename: J
authors.initials: J
authors.lastname: Eble
authors.forename: C
authors.initials: C
authors.lastname: Hennige
authors.forename: L V
authors.initials: LV
authors.lastname: Hennige
authors.forename: J P
authors.initials: JP
authors.lastname: Donohue
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005240:Feasibility Studies; D007668:Kidney / Q000473:pathology; D008297:Male; D011467:Prostate / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000097:blood / Q000473:pathology / Q000628:therapy*; D012007:Rectum / Q000473:pathology; D013813:Therapy, Computer-Assisted; D014464:Ultrasonic Therapy