title: Insertional editing in mitochondria of Physarum.
abstract: RNA produced from a number of genes on the mitochondrial (mt) DNA of Physarum polycephalum have nucleotides inserted at specific sites in their sequence. These insertions are spaced at approximately 25 nucleotide intervals and create open reading frames in mRNA and functional structure in tRNAs and rRNAs. Although most of the insertions at a site are single cytidines; single uridines and certain dinucleotides containing adenosine and guanosine as well as cytidine and uridine are also occasionally inserted at certain sites. This mixed nucleotide insertional RNA editing is unique among currently characterized editing systems.
authors.affiliation: Molecular and Cell Biology Program, University of Texas at Dallas, Richardson 75080.
authors.forename: D
authors.initials: D
authors.lastname: Miller
authors.forename: R
authors.initials: R
authors.lastname: Mahendran
authors.forename: M
authors.initials: M
authors.lastname: Spottswood
authors.forename: H
authors.initials: H
authors.lastname: Costandy
authors.forename: S
authors.initials: S
authors.lastname: Wang
authors.forename: M L
authors.initials: ML
authors.lastname: Ling
authors.forename: N
authors.initials: N
authors.lastname: Yang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA; D008969:Molecular Sequence Data; D016839:Physarum polycephalum / Q000201:enzymology / Q000235:genetics* / Q000648:ultrastructure; D012313:RNA / Q000378:metabolism*; D017393:RNA Editing; D000077278:RNA, Mitochondrial
chemical_list: D000077278:RNA, Mitochondrial; D012313:RNA; D004247:DNA