Intrathecal gene therapy for the treatment of leptomeningeal carcinomatosis. GTI 0108. A phase I/II study.
Oldfield
E H
EH
Ram
Z
Z
Chiang
Y
Y
Blaese
R M
RM
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000188:drug therapy / Q000628:therapy*; D002985:Clinical Protocols; D015774:Ganciclovir / Q000627:therapeutic use*; D015316:Genetic Therapy; D006801:Humans; D007276:Injections, Intraventricular; D007278:Injections, Spinal; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000628:therapy*; D008875:Middle Aged; D018139:Simplexvirus / Q000201:enzymology / Q000235:genetics; D013937:Thymidine Kinase / Q000235:genetics* / Q000627:therapeutic use
D013937:Thymidine Kinase; D015774:Ganciclovir