[Nephrotoxicity of drugs].
Setting out from the high prevalence of iatrogenic toxic effects on the kidney, the authors examine the pathophysiological mechanisms underlying this toxicity, and suggest their classification. The principal pathophysiologic and clinical models of the action of various groups of drugs responsible for these effects are discussed.
Paoletti
V
V
Cattedra di Medicina Interna, Università degli Studi di Roma La Sapienza.
Mammarella
A
A
Falaschi
R
R
Labbadia
G
G
Donnarumma
L
L
Musca
A
A
D000208:Acute Disease; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000633:toxicity; D000900:Anti-Bacterial Agents / Q000633:toxicity; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000633:toxicity; D000903:Antibiotics, Antineoplastic / Q000633:toxicity; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D009395:Nephritis, Interstitial / Q000139:chemically induced*; D009404:Nephrotic Syndrome / Q000139:chemically induced*
D000806:Angiotensin-Converting Enzyme Inhibitors; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000903:Antibiotics, Antineoplastic