[Cutaneous carcinoma and papillomavirus 5. Discovered during prolonged UVA photochemotherapy].
BACKGROUND
HPV 5 is an opportunistic oncogenic virus found mainly in patients with verruciform epidermodysplasia or in certain immunodepressed patients.


METHODS
We report the case of a 48-year-old patient who developed, over a 5 year period, 30 skin carcinomas after prolonged puvatreatment. HPV 5 was identified. The course has been stable under treatment with etretinate and alpha-interferon.


CONCLUSIONS
The role of ultraviolet irradiation as a carcinogenic agent is raised by this observation, both as a primary factor and as a local factor favouring immunosuppression and proliferation of opportunistic HVP.
Bayle-Lebey
P
P
Service de Dermatologie, Hôpital Purpan, Toulouse.
Labadie
F
F
Basset-Seguin
N
N
Bazex
J
J
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000821:virology*; D005050:Etretinate / Q000627:therapeutic use; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification*; D010778:Photochemotherapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy; D012878:Skin Neoplasms / Q000188:drug therapy / Q000821:virology*
D016898:Interferon-alpha; D005050:Etretinate