title: A randomized trial of abdominal incision suture technique and wound strength in rats.
abstract: OBJECTIVE
  To determine whether interrupted en bloc suture or continuous running mass suture technique for closure of abdominal incisions results in stronger wounds, and to determine the time required for each technique.
  
  
  METHODS
  Randomized trial.
  
  
  METHODS
  Arthur C. Guyton Animal Facilities, University of Mississippi Medical Center, Jackson.
  
  
  METHODS
  Male Sprague-Dawley rats.
  
  
  METHODS
  A midline laparotomy was performed on 103 rats that were separated into two groups using computer-generated random numbers. In group 1, incisions were repaired using a continuous mass closure suture technique. In group 2, incisions were repaired using an en bloc interrupted suture technique.
  
  
  METHODS
  Wound bursting pressure was determined on postoperative day 7. The time required to repair each incision was recorded.
  
  
  RESULTS
  Continuous mass closure suture technique resulted in significantly greater wound strength (P < .05) and required significantly less time (P < .000001).
  
  
  CONCLUSIONS
  Continuous mass closure suture technique is superior to interrupted en bloc closure with respect to wound strength and closure time.
authors.affiliation: Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, USA.
authors.forename: M H
authors.initials: MH
authors.lastname: Seid
authors.forename: L M
authors.initials: LM
authors.lastname: McDaniel-Owens
authors.forename: G V
authors.initials: GV
authors.lastname: Poole
authors.forename: G R
authors.initials: GR
authors.lastname: Meeks
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery*; D000818:Animals; D008297:Male; D011312:Pressure; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013536:Suture Techniques; D013718:Tensile Strength