title: [Severe and complicated forms of chronic pancreatitis].
abstract: A total of 437 patients with chronic pancreatitis (CP) were examined. The authors detected interstitial or acute, parenchymal or recurrent, hyperplastic or pseudotumorous, and cystic variants in 91 (20.8%), 218 (49.9%), 78 (17.8%), 22 (5.1%), and 28 (6.4%) patients, respectively, Severe types due to the permanent pain syndrome, substantial weight loss and overall intoxication phenomena were seen in 21.5%. Complications of chronic pancreatitis were revealed in 32.3%. Pyoseptic complications (11.2%), anicteric cholestasis (8.5%), subhepatic portal hypertension (8.0%), cholestatic jaundice (7.8%) were most common. Immunodeficiency states developed with long-term treatment of CP. A small portion (0.9%) of patients with CP developed pancreatic carcinoma. 3% of patients had deaths directly due to the active course of the disease whose causes were pyoseptic processes, pancreatic carcinoma and profuse hemorrhages from exulcerations of the duodenal postbulbar part.
authors.forename: A S
authors.initials: AS
authors.lastname: Ivlev
authors.forename: A I
authors.initials: AI
authors.lastname: Khazanov
authors.forename: G G
authors.initials: GG
authors.lastname: Piskunov
authors.forename: A P
authors.initials: AP
authors.lastname: Vasil'ev
authors.forename: V G
authors.initials: VG
authors.lastname: Nikitin
authors.forename: Iu K
authors.initials: IuK
authors.lastname: Seleznev
authors.forename: I B
authors.initials: IB
authors.lastname: Lapaev
authors.forename: V A
authors.initials: VA
authors.lastname: Belogolovtsev
authors.forename: D K
authors.initials: DK
authors.lastname: Stepuro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D006801:Humans; D006965:Hyperplasia / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D015994:Incidence; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality