title: Life-threatening infection in two children with hemoglobin S-beta-thalassemia.
abstract: Life-threatening infections with Streptococcus pneumoniae and parvovirus occurred in two patients with hemoglobin S-beta-thalassemia. We recommend that acute febrile illnesses in the presence of any hemoglobinopathy be considered potentially life threatening, and managed accordingly.
authors.affiliation: Division of Pediatric Critical Care and Anesthesia, Vanderbilt University, Nashville, Tennessee 37232, USA.
authors.forename: A
authors.initials: A
authors.lastname: Lynch
authors.forename: J D
authors.initials: JD
authors.lastname: Tobias
mesh_terms: D000293:Adolescent; D016470:Bacteremia / Q000150:complications* / Q000503:physiopathology; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000150:complications*; D010322:Parvoviridae Infections / Q000150:complications* / Q000503:physiopathology; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D011008:Pneumococcal Infections / Q000150:complications* / Q000503:physiopathology; D014766:Viremia / Q000150:complications* / Q000503:physiopathology; D017086:beta-Thalassemia / Q000150:complications* / Q000503:physiopathology