[Severe and complicated forms of chronic pancreatitis].
A total of 437 patients with chronic pancreatitis (CP) were examined. The authors detected interstitial or acute, parenchymal or recurrent, hyperplastic or pseudotumorous, and cystic variants in 91 (20.8%), 218 (49.9%), 78 (17.8%), 22 (5.1%), and 28 (6.4%) patients, respectively, Severe types due to the permanent pain syndrome, substantial weight loss and overall intoxication phenomena were seen in 21.5%. Complications of chronic pancreatitis were revealed in 32.3%. Pyoseptic complications (11.2%), anicteric cholestasis (8.5%), subhepatic portal hypertension (8.0%), cholestatic jaundice (7.8%) were most common. Immunodeficiency states developed with long-term treatment of CP. A small portion (0.9%) of patients with CP developed pancreatic carcinoma. 3% of patients had deaths directly due to the active course of the disease whose causes were pyoseptic processes, pancreatic carcinoma and profuse hemorrhages from exulcerations of the duodenal postbulbar part.
Ivlev
A S
AS
Khazanov
A I
AI
Piskunov
G G
GG
Vasil'ev
A P
AP
Nikitin
V G
VG
Seleznev
Iu K
IuK
Lapaev
I B
IB
Belogolovtsev
V A
VA
Stepuro
D K
DK
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D006801:Humans; D006965:Hyperplasia / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D015994:Incidence; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality