title: Expression of adhesion molecules by endothelial cells of early human decidua.
abstract: The expression of adhesion molecules by endothelial cells (EC) of early human decidua was studied with monoclonal antibodies and the immunoperoxidase technique. Although E-selectin, INCAM-110 and VCAM-1 were poorly detected on decidual EC, ICAM-1, P-selectin and DR antigens were highly expressed by these cells, some of which showed high endothelial venule-like morphology. Our results suggest that decidual EC are activated, and are probably involved in the active recruitment of leucocytes.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Granada, Spain.
authors.forename: C G
authors.initials: CG
authors.lastname: Tortosa
authors.forename: M L
authors.initials: ML
authors.lastname: Vargas
authors.forename: M
authors.initials: M
authors.lastname: Cámara
authors.forename: P
authors.initials: P
authors.lastname: Alemán
authors.forename: M J
authors.initials: MJ
authors.lastname: Montes
authors.forename: C
authors.initials: C
authors.lastname: Ruiz
authors.forename: E G
authors.initials: EG
authors.lastname: Olivares
mesh_terms: D015815:Cell Adhesion Molecules / Q000032:analysis*; D003656:Decidua / Q000098:blood supply / Q000737:chemistry*; D004730:Endothelium, Vascular / Q000737:chemistry* / Q000166:cytology; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins / Q000032:analysis*; D011247:Pregnancy
chemical_list: D015815:Cell Adhesion Molecules; D006684:HLA-DR Antigens; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins; D018799:Intercellular Adhesion Molecule-1