Pallidotomy for Parkinson's disease.
Ventroposterolateral pallidotomy was used in the surgical treatment of 259 patients suffering from intractable Parkinson's disease. Pallidotomy was equally effective against tremor, rigor, bradykinesia, and the L-dopa-induced dyskinesias. The effect of surgery seemed to be long-lasting, and side effects were rare. The author believes that the beneficial effect of pallidotomy is based on interruption of striopallidal and pallidosubthalamic pathways.
Laitinen
L V
LV
Sophiahemmet Hospital, Stockholm, Sweden.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005917:Globus Pallidus / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000601:surgery*; D011183:Postoperative Complications; D012607:Scotoma / Q000209:etiology; D013788:Thalamus / Q000601:surgery; D016896:Treatment Outcome