Selective blockade of sensory response of the carotid body to hypoxia by NK-1 receptor antagonist CP-96,345.
Prabhakar
N R
NR
Department of Medicine, Case Western Reserve University, Cleveland, OH 44106.
Snider
R M
RM
Lowe
J A
JA
Cao
H
H
D000818:Animals; D001713:Biphenyl Compounds / Q000494:pharmacology*; D002344:Carotid Body / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology; D002415:Cats; D002628:Chemoreceptor Cells / Q000187:drug effects / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D064729:Neurokinin-1 Receptor Antagonists; D009475:Neurons, Afferent / Q000187:drug effects / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D018040:Receptors, Neurokinin-1 / Q000502:physiology; D013373:Substance P / Q000037:antagonists & inhibitors*
D001713:Biphenyl Compounds; D064729:Neurokinin-1 Receptor Antagonists; D018040:Receptors, Neurokinin-1; D013373:Substance P; D010100:Oxygen; C066892:CP 96345