Estrogen receptor analysis of human temporomandibular disc.
Epidemiological studies of temporomandibular joint (TMJ) dysfunction suggest a significant female predilection for symptomatic disease. Because previous primate research revealed sexual dimorphism in the estrogen receptors (ER) present in the masticatory apparatus, this investigation was undertaken to assess the presence of ER in human TMJ tissues. The negative findings suggest that ER status does not contribute to symptomatic TMJ disease.
Campbell
J H
JH
Department of Oral Medicine, Pathology, and Surgery, University of Michigan, Ann Arbor 48109.
Courey
M S
MS
Bourne
P
P
Odziemiec
C
C
D000293:Adolescent; D000328:Adult; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology; D002358:Cartilage, Articular / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002478:Cells, Cultured; D005260:Female; D005615:Freezing; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis*; D013194:Staining and Labeling; D013704:Temporomandibular Joint / Q000473:pathology*; D013705:Temporomandibular Joint Disorders / Q000473:pathology*; D016707:Tissue Fixation
D011960:Receptors, Estrogen