title: [ACTH producing pituitary adenoma with multiple intracranial metastases and spinal dissemination].
abstract: A 34-year-old male developed multiple intracranial and intraspinal metastases from an invasive ACTH secreting pituitary adenoma. He was initially admitted to our hospital complaining of visual loss 10 years ago, presenting a pituitary tumor with suprasellar extension. At first, transsphenoidal surgery was performed, and histological finding was pituitary apoplexy. He developed recurrence of the tumor 2 times. At the second, third and fourth operation, the histological finding was an ACTH secreting pituitary adenoma with atypia. Metastases within the central-nervous system of pituitary adenoma is a rare entity and only 21 cases have been published. A review of previously published cases follows.
authors.affiliation: Department of Neurosurgery, Oita Medical University.
authors.forename: J
authors.initials: J
authors.lastname: Matsuyama
authors.forename: T
authors.initials: T
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Hori
mesh_terms: D000236:Adenoma / Q000378:metabolism* / Q000473:pathology; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000328:Adult; D001932:Brain Neoplasms / Q000556:secondary*; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000556:secondary*
chemical_list: D000324:Adrenocorticotropic Hormone