Reducing bodies in distal myopathy with rimmed vacuole formation.
A 42-year-old woman with distal myopathy with rimmed vacuoles had intracytoplasmic inclusion bodies similar to those described in reducing body myopathy. Since these inclusions were found in fibers with high acid phosphatase activity and occasional rimmed vacuoles, their formation appeared to correlate with active myofibrillar degeneration, but their origin remains unknown.
Kiyomoto
B H
BH
Department of Ultrastructural Research, National Center of Neurology and Psychiatry, Tokyo, Japan.
Murakami
N
N
Kishibayashi
J
J
Sunohara
N
N
Nonaka
I
I
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D002479:Inclusion Bodies; D008854:Microscopy, Electron; D018485:Muscle Fibers, Skeletal / Q000473:pathology*; D018482:Muscle, Skeletal; D009133:Muscular Atrophy / Q000473:pathology*