title: [A trial of the use of the preparation Arthrotec for treating rheumatic diseases].
abstract: A clinical trial of arthrotek (Searle) in 60 RA patients aged 16-77 years demonstrated its high anti-inflammatory activity in 47 of them. These patients have received a complete treatment course, 10 patients were not included in the overall estimations because of side affects (gastric pains and nausea) causing them to withdraw early in the treatment course, 3 patients were nonresponders. The responders experienced attenuation of joint pain, morning stiffness. Inflammation in some joints declined, the articular index decreased.
authors.forename: V A
authors.initials: VA
authors.lastname: Nasonova
authors.forename: Ia A
authors.initials: IaA
authors.lastname: Sigidin
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Murav'ev
authors.forename: O I
authors.initials: OI
authors.lastname: Lebedeva
authors.forename: V I
authors.initials: VI
authors.lastname: Burtsev
authors.forename: Z P
authors.initials: ZP
authors.lastname: Rashchupkina
authors.forename: V P
authors.initials: VP
authors.lastname: Krikunov
authors.forename: A V
authors.initials: AV
authors.lastname: Kuzin
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: N V
authors.initials: NV
authors.lastname: Chichasova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D004008:Diclofenac / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016595:Misoprostol / Q000009:adverse effects / Q000627:therapeutic use*; D012074:Remission Induction; D012216:Rheumatic Diseases / Q000175:diagnosis / Q000188:drug therapy*; D012426:Russia; D013607:Tablets
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; C078133:Arthrotec; D004338:Drug Combinations; D013607:Tablets; D016595:Misoprostol; D004008:Diclofenac