title: [The effect of weightlessness on amphibians. The ultimobranchial body].
abstract: C-cells of Pleurodeles waltilii ultimobranchial bodies (ULT) were studied after a series of two-week spaceflight on the biosatellites. It was shown that under conditions of weightlessness the hypertrophy of ULT and calcitonin secretion activation occurred. Calcitonin accumulated into the ULT which resulted in metaplasia of the surrounding tissues, organ calcification and C-cells death. After landing, the regenerative processes which were not manifest in weightlessness occurred. They were similar to those of embryonic development of the organ.
authors.forename: N V
authors.initials: NV
authors.lastname: Besova
authors.forename: S V
authors.initials: SV
authors.lastname: Savelev
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D007150:Immunohistochemistry; D010999:Pleurodeles / Q000033:anatomy & histology*; D012426:Russia; D013026:Space Flight; D013194:Staining and Labeling / Q000379:methods; D013997:Time Factors; D014460:Ultimobranchial Body / Q000378:metabolism / Q000473:pathology*; D014893:Weightlessness / Q000009:adverse effects*