[Prevention of adhesions with dextrans].
The effect of doses and molecular weight of dextrans on intraperitoneal adhesion formation were studied in an animal model. With increasing molecular weight the maximum effect is achieved with smaller quantities of the solutions. Because of the adhesion preventing properties, in cases of single and also multiple applications, dextran 60 should be preferred to other high molecular solutions.
Gauwerky
J F
JF
Universtäts-Frauenklinik Heidelberg.
Rogmans
G
G
Bastert
G
G
D000818:Animals; D003911:Dextrans / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005836:Genitalia, Female / Q000601:surgery*; D008970:Molecular Weight; D010532:Peritoneal Diseases / Q000517:prevention & control*; D010537:Peritoneum / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*; D051381:Rats; D017208:Rats, Wistar; D000267:Tissue Adhesions
D003911:Dextrans