title: Morphological findings of an interrelationship among the neurosecretory axons of the neural lobe of the hypophysis.
abstract: In order to establish whether osmotic stimuli induce variations in the contact regions among neurosecretory axons of the neural lobe of the hypophysis, adult Sprague-Dawley rats of both sexes were treated with furosemide, a diuretic drug. Contacts between adjacent membranes with no condensations of the axolemma but increase in their osmiophilia were observed. After treatment with furosemide interaxonal contacts were significantly increased (p < 0.01, in relation to control animals). Additionally, following treatment with furosemide, axo-axonic synapses among the axons of the neural lobe were found. These findings suggest the existence of interactions among activated neurosecretory axons of the neural lobe of the adult rat.
authors.affiliation: Department of Human Anatomy and Histology, Faculty of Medicine, University of Salamanca, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Vazquez
authors.forename: F
authors.initials: F
authors.lastname: Sanchez
authors.forename: E
authors.initials: E
authors.lastname: Blanco
authors.forename: J A
authors.initials: JA
authors.lastname: Juanes
authors.forename: M
authors.initials: M
authors.lastname: Rubio
authors.forename: J M
authors.initials: JM
authors.lastname: Riesco
authors.forename: R J
authors.initials: RJ
authors.lastname: Vazquez
authors.forename: J
authors.initials: J
authors.lastname: Carretero
mesh_terms: D000818:Animals; D001369:Axons / Q000187:drug effects / Q000648:ultrastructure*; D005260:Female; D005665:Furosemide / Q000008:administration & dosage*; D008297:Male; D009489:Neurosecretion; D010902:Pituitary Gland / Q000187:drug effects / Q000648:ultrastructure*; D017729:Presynaptic Terminals / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D005665:Furosemide