The marker for nitric oxide synthase, NADPH-diaphorase, co-localizes with GABA in horizontal cells and cells of the inner retina in the carp retina.
NADPH-diaphorase histochemistry selectively stained discrete populations of neurons contributing to the inner plexiform layer of the carp retina. In addition H1 horizontal cells contributing to the outer plexiform layer were labeled. In these cells as in a subpopulation of the labeled cells in the inner retina, NADPH-activity co-localized with GABA immunoreactivity. NADPH-activity is a direct marker for NO synthesis and it is concluded that NO might be an important mediator of light-dependent adaptational processes in the outer retina.
Weiler
R
R
Department of Neurobiology, University of Oldenburg, Germany.
Kewitz
B
B
D000594:Amino Acid Oxidoreductases / Q000378:metabolism*; D000818:Animals; D015415:Biomarkers; D002347:Carps / Q000378:metabolism*; D007150:Immunohistochemistry; D008027:Light; D009252:NADPH Dehydrogenase / Q000378:metabolism*; D019001:Nitric Oxide Synthase; D009580:Nitroblue Tetrazolium; D012160:Retina / Q000166:cytology / Q000378:metabolism*; D017949:Retinal Cone Photoreceptor Cells / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D015415:Biomarkers; D009580:Nitroblue Tetrazolium; D005680:gamma-Aminobutyric Acid; D019001:Nitric Oxide Synthase; D000594:Amino Acid Oxidoreductases; D009252:NADPH Dehydrogenase