Cardiovascular sympathoinhibitory neurons form an extended longitudinal column in cat lateral medulla.
A search for vasomotor depressor sites in the lateral medullary brainstem of anesthetized cat using microinjections of AMPA has delineated a longitudinal column of sympathoinhibitory neurons consisting of the rostral depressor area, the caudal ventrolateral medulla, and a new intermediate depressor area. Systematic blockade of these three subregions with bilateral microinjections of kynurenic acid indicates a uniform involvement of the entire column with sympathetic baroreflex, but a slightly greater involvement of the anterior portion, over the posterior, with regulation of cardiovascular tone.
Dempesy
C W
CW
Department of Neurosurgery, Tulane University School of Medicine, New Orleans, LA 70112.
Richardson
D E
DE
Fontana
C J
CJ
D000818:Animals; D001370:Axonal Transport; D001931:Brain Mapping; D002319:Cardiovascular System / Q000294:innervation*; D002415:Cats; D005260:Female; D007051:Ibotenic Acid / Q000031:analogs & derivatives; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology* / Q000502:physiology; D008845:Microinjections; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D011311:Pressoreceptors / Q000502:physiology; D012018:Reflex; D013564:Sympathetic Nervous System / Q000502:physiology*; D014628:Vagotomy; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
D007051:Ibotenic Acid; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid