[Carbamide kinetics in the evaluation of the therapeutic quality of hemodialysis].
A urea kinetic analysis, (the Sargent and Gotch model), was applied to 62 haemodialysis patients. The protein catabolic rate was below 1 g/kg/day in 56.5% of the patients and 66.3% had a KT/V (Clearance x Time/Volume) below 1. The median KT/V was 0.90 and the median normalized protein catabolic rate was 0.95 g/kg/day. KT/V was strongly correlated to protein intake (normalized protein catabolic rate). It is concluded that urea kinetic modelling is a practical tool for assessing the dialysis adequacy and nutritional status of haemodialyzed patients.
Ekelund
B
B
Nefrologisk afdeling, Hvidovre Hospital, København.
Ladefoged
S D
SD
Kverneland
A
A
D003430:Cross-Sectional Studies; D006801:Humans; D008954:Models, Biological; D006435:Renal Dialysis / Q000592:standards*; D014508:Urea / Q000493:pharmacokinetics*
D014508:Urea