[Blocking of the latrotoxin channel by cadmium ions].
Influence of cadmium ions on current-voltage characteristics of latrotoxin treated BLM was studied. It was established that the affinity of cadmium ions to cis-mouth of a channel is substantially more than to trans-mouth for all the studied voltages. It was shown than the blocking of latrotoxin channels can occur by screening of the electric potential at the entrance of the pore.
Sabirov
R Z
RZ
Iul'chibaeva
N A
NA
Krasil'nikov
O V
OV
D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D007473:Ion Channels / Q000187:drug effects*; D008051:Lipid Bilayers; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D051381:Rats; D013111:Spider Venoms / Q000378:metabolism*
D007473:Ion Channels; D008051:Lipid Bilayers; D013111:Spider Venoms; D002104:Cadmium; C020763:alpha-latrotoxin