Movement disorders in the eosinophilia-myalgia syndrome: tremor, myoclonus, and myokymia.
OBJECTIVE
To describe the development of tremor, myoclonus, and myokymia as chronic sequelae of eosinophilia-myalgia syndrome (EMS).


METHODS
Four patients among a cohort of 57 individuals with EMS followed prospectively were identified to have objective movement disorders. Electrophysiologic findings were assessed by recording of electromyographic activity from pairs of upper extremity antagonist muscles using 2 input channels.


RESULTS
Clinical and electrophysiologic studies documented the presence of tremor (4 patients), myoclonus (3 patients), and myokymia (1 patient) as late sequelae of EMS.


CONCLUSIONS
The recognition of these movement disorders extends the spectrum of chronic neurologic disease in EMS.
Kaufman
L D
LD
Department of Medicine (Division of Allergy, Rheumatology, and Clinical Immunology, State University of New York at Stony Brook 11794-8161.
Kaufman
M A
MA
Krupp
L B
LB
D000328:Adult; D015331:Cohort Studies; D004576:Electromyography; D016603:Eosinophilia-Myalgia Syndrome / Q000150:complications*; D005207:Fasciculation / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000209:etiology*; D014202:Tremor / Q000209:etiology*; D014364:Tryptophan / Q000009:adverse effects
D014364:Tryptophan