Novel substance P analogues inhibit circular muscle contraction of guinea pig ileum and depolarization of new born rat spinal cord induced by substance P.
Mochizuki
T
T
University of Shizuoka School of Pharmaceutical Sciences, Japan.
Ohshima
K
K
Kuwahara
A
A
Yanagisawa
M
M
Otsuka
M
M
Yanaihara
N
N
D000818:Animals; D000831:Animals, Newborn; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects / Q000502:physiology*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D015288:Neurokinin A / Q000494:pharmacology; D051381:Rats; D013116:Spinal Cord / Q000187:drug effects / Q000502:physiology*; D013329:Structure-Activity Relationship; D013373:Substance P / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000494:pharmacology*
D013373:Substance P; D015288:Neurokinin A