Effect of human granulocyte colony stimulating factor on neuroblastoma cell growth.
We have studied the effect of recombinant human granulocyte colony-stimulating factor (G-CSF) on the growth of three different human neuroblastoma (NB) cell lines, using a clonal cell culture and a short proliferation test. The results have shown a lack of effect of G-CSF on the three cell lines. These data promote the use, in clinical trials, of G-CSF as adjunctive treatment in children with NB receiving intensive chemotherapy.
Morel
M
M
CDTS du Val de marne, Henri Mondor Hospital, Créteil, France.
Beaujean
F
F
Le Forestier
C
C
Hartmann
O
O
Lemerle
J
J
Duedari
N
N
D002455:Cell Division / Q000187:drug effects; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D009447:Neuroblastoma / Q000473:pathology*; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014410:Tumor Stem Cell Assay
D016179:Granulocyte Colony-Stimulating Factor