[The development of serum alkaline phosphatase and gamma-glutamyl transpeptidase in early stages of primary biliary cirrhosis].
We carried out a retrospective study for the development of biochemical abnormalities in nine patients with early stages of primary biliary cirrhosis (PBC). All patients had elevated serum alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (gamma-GTP) levels when the diagnosis of PBC was obtained. In all cases, serum gamma-GTP levels initially increased, followed by the elevation of ALP. In the routine laboratory tests gamma-GTP is more sensitive than ALP for the screening for early PBC.
Ohhira
M
M
Department of Internal Medicine III, Asahikawa Medical College.
Ohhira
M
M
Matsumoto
A
A
Ohta
H
H
Okuno
K
K
Okamoto
M
M
Taya
N
N
Namiki
M
M
D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D005723:gamma-Glutamyltransferase / Q000097:blood*
D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase