Specific recognition of purified Cu,Zn superoxide dismutase from Aspergillus fumigatus by immune human sera.
Sera from 22 (84.6%) of 26 patients with confirmed Aspergillus infections recognized a purified Cu,Zn superoxide dismutase from A. fumigatus on Western blots (immunoblots). Sera from 32 (71%) of 45 patients with suspected Aspergillus infections were reactive to the superoxide dismutase. Normal human sera and sera from patients with other infections were unreactive.
Hamilton
A J
AJ
Dermatology Laboratory, St. Johns' Institute, Guys Hospital, London, England.
Holdom
M D
MD
Hay
R J
RJ
D000908:Antibodies, Fungal / Q000097:blood*; D000918:Antibody Specificity; D000946:Antigens, Fungal / Q000302:isolation & purification; D001228:Aspergillosis / Q000175:diagnosis / Q000276:immunology* / Q000382:microbiology; D001232:Aspergillus fumigatus / Q000201:enzymology* / Q000276:immunology*; D006801:Humans; D012698:Serologic Tests; D013482:Superoxide Dismutase / Q000276:immunology* / Q000302:isolation & purification
D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D013482:Superoxide Dismutase