Ivermectin resistant Haemonchus contortus in Louisiana lambs.
Fifteen weaned crossbred (Suffolk x Louisiana Native) lambs were treated with albendazole (10 mg kg-1) to remove existing nematode infections. They were inoculated with Haemonchus contortus infective larvae from a residual population surviving treatment with the oral formulation of ivermectin (0.2 mg kg-1). One group of five lambs remained untreated, another group of five was treated with the injectable formulation of ivermectin (0.2 mg kg-1), and a third group of five was treated with the oral formulation of ivermectin (0.2 mg kg-1). Subsequent to the treatments, there was essentially no difference in mean fecal egg count or mean number of H. contortus recovered at necropsy between the three groups.
Miller
J E
JE
Department of Animal Science, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803-4210.
Barras
S R
SR
D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects* / Q000302:isolation & purification; D007559:Ivermectin / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008145:Louisiana; D010270:Parasite Egg Count; D012756:Sheep / Q000469:parasitology*; D012757:Sheep Diseases
D007559:Ivermectin; D015766:Albendazole