title: Potential role of serum troponin T in cardiomyocyte injury in the broiler ascites syndrome.
abstract: 1. Cardiac troponin T is a recently developed serological marker used as a sensitive diagnostic tool for early myocardial damage in 'at risk' human patients. 2. Serum troponin T values were measured in young 30-d-old broilers with ascites and in healthy age-matched flockmates. 3. The data showed a significant increase (P < 0.001) in troponin T values in ascitic broilers compared with control birds. A similar increase in the arterial pressure index in ascitic birds indicated a good positive correlation at this age. 4. The results suggest that this new assay cross-reacts with chicken cardiac troponin T antigen and that it may be an important indicator of myocardial cell damage for use in future genetic selection programmes in the combat against ascites.
authors.affiliation: Roslin Institute (Edinburgh), Midlothian, Scotland.
authors.forename: M H
authors.initials: MH
authors.lastname: Maxwell
authors.forename: G W
authors.initials: GW
authors.lastname: Robertson
authors.forename: D
authors.initials: D
authors.lastname: Moseley
mesh_terms: D000818:Animals; D001201:Ascites / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D015415:Biomarkers / Q000097:blood; D002645:Chickens; D006331:Heart Diseases / Q000175:diagnosis / Q000662:veterinary*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000662:veterinary*; D011201:Poultry Diseases / Q000175:diagnosis*; D012016:Reference Values; D013577:Syndrome; D014336:Troponin / Q000097:blood*; D020107:Troponin T
chemical_list: D015415:Biomarkers; D014336:Troponin; D020107:Troponin T