title: Effect of dissolved oxygen levels on biosynthesis of aureofungin by Streptoverticillium cinnamoneum var. terricola.
abstract: Biosynthesis of aureofungin by Streptoverticillium cinnamoneum var, terricola was found to be an oxygen dependent reaction. An accelerated rate of aureofungin production, along with a better yield coefficient were obtained under conditions of enhanced aeration during fermentation. A higher oxygen transfer rate was found to stimulate aureofungin A, and suppresses aureofungin B formation.
authors.affiliation: Hindustan Antibiotics Ltd., Pimpri, Pune.
authors.forename: P V
authors.initials: PV
authors.lastname: Patankar
authors.forename: R K
authors.initials: RK
authors.lastname: Nanda
authors.forename: S R
authors.initials: SR
authors.lastname: Naik
mesh_terms: D000935:Antifungal Agents / Q000096:biosynthesis*; D003470:Culture Media; D010100:Oxygen / Q000494:pharmacology*; D011090:Polyenes / Q000378:metabolism; D013306:Streptomycetaceae / Q000187:drug effects / Q000378:metabolism*
chemical_list: D000935:Antifungal Agents; D003470:Culture Media; D011090:Polyenes; C030205:aureofungin B; C006651:aureofungin A; D010100:Oxygen