[Adenosine triphosphate (ATP) in the management of paroxysmal supraventricular tachycardia: experience in the neonatal period].
OBJECTIVE
The management of supraventricular tachycardia (SVT) in infants is somewhat controversial since numerous methods of treatment are effective. Regardless of the treatment chosen, it is important to quickly stop the tachycardia in neonates with SVT because they may suddenly become hemodynamically unstable.


METHODS
Seventeen episodes of SVT treated with intravenous ATP are studied in 3 newborns (two were preterm infants: 30 and 34 weeks of pregnancy). Ages at presentation ranged from 2 to 27 days.


RESULTS
ATP is effective in all episodes of SVT, with a mean intravenous doses between 0.10 and 0.50 mg/kg/dose. All patients showed short sinus arrest after ATP. No adverse side effects or hemodynamics changes occurred after ATP administration.


CONCLUSIONS
ATP is a safe and reliable antiarrhythmic in neonatal period, including prematurity. We reviewed the experience in ATP management of SVT, mainly in pediatric population.
González de Dios
J
J
Servicio de Cardiología, Hospital Infantil La Paz, Madrid.
Burgueros Valero
M
M
García Guereta
L
L
Moreno Granados
F
F
Pérez Rodríguez
J
J
Quero Jiménez
J
J
D000241:Adenosine / Q000008:administration & dosage / Q000627:therapeutic use; D000255:Adenosine Triphosphate / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D000367:Age Factors; D002648:Child; D004070:Digitalis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy; D007275:Injections, Intravenous; D008297:Male; D010946:Plants, Medicinal; D010947:Plants, Toxic; D011802:Quinidine / Q000627:therapeutic use; D012016:Reference Values; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy*; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*
D000255:Adenosine Triphosphate; D011802:Quinidine; D000241:Adenosine
Manejo del adenosín trifosfato (ATP) en la taquicardia paroxística supraventricular: experiencia en el período neonatal.