title: [Effect of xiaoyu pian on new platelet aggregation defect].
abstract: The Xiaoyu pian (XYP, mainly consisted of prunus persica, Carthamus tinctorius, Glycyrrhiza uralensis, etc) was used to treat patients with new platelet aggregation defect. Patients were divided into 2 groups, the TCM group (72 cases) treated with XYP and the control group (65 cases) treated with vitamin C and P and/or adrenosem for at least 3 months. The results showed that marked effective rate was 87.5% in TCM group and 35.4% in control group (chi 2 = 39.7, P < 0.01); the recovery rate of platelet was 91.8% in the former and 10.3% in the latter (chi 2 = 71.4, P < 0.01); the recurrence rate of follow-up (6 months after treatment) was 30.8% in the former and 82.1% in the latter (chi 2 = 19.2, P < 0.01). The difference between two groups was very significant. The results suggested that XYP could regulate the hemostatic action and the platelet aggregation function. It is worthwhile to use XYP as an hemostatic clinically.
authors.affiliation: Xiehe Hospital, Tongji Medical University, Wuhan.
authors.forename: D
authors.initials: D
authors.lastname: Shen
authors.forename: L
authors.initials: L
authors.lastname: Shen
authors.forename: A L
authors.initials: AL
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000323:Adrenochrome / Q000008:administration & dosage / Q000031:analogs & derivatives; D000328:Adult; D001205:Ascorbic Acid / Q000008:administration & dosage; D001791:Blood Platelet Disorders / Q000097:blood / Q000188:drug therapy*; D002135:Calcium-Binding Proteins; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005299:Fertility Agents / Q000008:administration & dosage; D006487:Hemostasis / Q000187:drug effects; D006490:Hemostatics / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D027361:Organic Anion Transporters; D010974:Platelet Aggregation / Q000187:drug effects
chemical_list: D002135:Calcium-Binding Proteins; D004365:Drugs, Chinese Herbal; D005299:Fertility Agents; D006490:Hemostatics; D027361:Organic Anion Transporters; C008822:citrin; D000323:Adrenochrome; C073338:carbazochrome; D001205:Ascorbic Acid