Out-patient cognitive-behavioural therapy with amitriptyline for chronic non-malignant pain: a comparative study with 6-month follow-up.
A study was carried out in a multidisciplinary pain clinic with the purpose of comparing the effectiveness of outpatient cognitive-behavioural therapy (CBT) with amitriptyline (AMI) to that of supportive therapy with AMI. The treatments were given weekly over 8 weeks. Global and continuous outcome measures were used. Analysis was by chi-square for global data and MANOVA with baseline scores as covariants for continuous variables. No significant differences could be demonstrated. The scores over a 6-month follow-up period suggested a delayed positive advantage for CBT but this only approached and did not achieve statistical significance. The findings are discussed.
Pilowsky
Issy
I
Department of Psychiatry, University of Adelaide, Adelaide 5000 Australia Department of Anaesthesia and Intensive Care, University of Adelaide, Adelaide 5000 Australia Psychiatric Service, Royal Adelaide Hospital, Adelaide 5000 Australia Pain Unit and Intensive Care, Royal Adelaide Hospital, Adelaide 5000 Australia.
Spence
Neil
N
Rounsefell
Bruce
B
Forsten
Carole
C
Soda
Jacqueline
J
D000328:Adult; D000639:Amitriptyline / Q000627:therapeutic use*; D001521:Behavior Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D018710:Pain Clinics; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
D000639:Amitriptyline