Pseudo-pseudohypertriglyceridemia: a case of increased free glycerol without evidence for glycerol kinase deficiency.
High concentrations of glycerol in plasma may result in overestimation of triglycerides in chemical and enzymatic assays. Known causes of increased glycerol concentrations in blood include glycerol-contaminated blood-collector tubes and pseudohypertriglyceridemia, a condition caused by genetic defects in the gene for glycerol kinase. We report a patient with sudden hearing loss who presented with an increased blood glycerol concentration after undergoing an oral glycerol test.
Nauck
M
M
Department of Clinical Chemistry, Albert Ludwigs-University, Freiburg, Germany.
Winkler
K
K
Siekmeier
R
R
Marangos
N
N
Richter
B
B
März
W
W
Wieland
H
H
D000328:Adult; D004587:Electrophoresis, Agar Gel; D005189:False Positive Reactions; D005990:Glycerol / Q000097:blood*; D005991:Glycerol Kinase / Q000172:deficiency*; D034381:Hearing Loss / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood*; D007700:Kinetics; D008297:Male; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D005991:Glycerol Kinase; D005990:Glycerol