title: Effects of 2,4-dichlorophenoxyacetic acid on polyamine transport and metabolism in Azospirillum brasilense Cd.
abstract: We had previously demonstrated that 1 mM 2,4-D inhibited cell growth, nucleic acid synthesis and protein synthesis (at the ribosomal level) of Azospirillum brasilense. These alterations were prevented by the presence of polyamines in the culture medium. On the other hand, polyamines did not affect the 2,4-D uptake. In this paper we demonstrate that 2,4-D alters the metabolism of polyamines and increases their uptake.
authors.affiliation: Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Córdoba, Argentina.
authors.forename: G
authors.initials: G
authors.lastname: Mori
authors.forename: A
authors.initials: A
authors.lastname: Fabra
authors.forename: S
authors.initials: S
authors.lastname: Castro
authors.forename: V
authors.initials: V
authors.lastname: Rivarola
authors.forename: W
authors.initials: W
authors.lastname: Giordano
authors.forename: H
authors.initials: H
authors.lastname: Balegno
mesh_terms: D015084:2,4-Dichlorophenoxyacetic Acid / Q000494:pharmacology*; D015806:Azospirillum brasilense / Q000187:drug effects* / Q000378:metabolism*; D015317:Biogenic Polyamines / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002262:Carboxy-Lyases / Q000378:metabolism; D009955:Ornithine Decarboxylase / Q000378:metabolism; D011700:Putrescine / Q000378:metabolism; D013095:Spermidine / Q000031:analogs & derivatives / Q000378:metabolism; D011436:Spermidine Synthase / Q000378:metabolism
chemical_list: D015317:Biogenic Polyamines; C017988:N(1)-acetylspermidine; D015084:2,4-Dichlorophenoxyacetic Acid; D011436:Spermidine Synthase; D002262:Carboxy-Lyases; D009955:Ornithine Decarboxylase; C019722:arginine decarboxylase; D013095:Spermidine; D011700:Putrescine