Current theories of pathogenesis and treatment of nonocclusive mesenteric ischemia.
Nonocclusive mesenteric ischemia (NOMI) is a poorly understood condition marked by progressive intestinal ischemia leading to infarction, sepsis, and death in a high proportion of patients. The mortality rate for this intestinal disorder remains high, even when the diagnosis is made early in the disease course. This paper presents a comprehensive review of NOMI with a detailed discussion of its history, pathophysiology, diagnosis, and treatment.
Wilcox
M G
MG
Department of Surgery, Indiana University School of Medicine, Indianapolis, USA.
Howard
T J
TJ
Plaskon
L A
LA
Unthank
J L
JL
Madura
J A
JA
D000818:Animals; D004750:Enteral Nutrition / Q000009:adverse effects; D006801:Humans; D007239:Infections / Q000150:complications; D007413:Intestinal Mucosa / Q000378:metabolism; D007511:Ischemia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008643:Mesentery / Q000098:blood supply*; D015427:Reperfusion Injury / Q000150:complications; D014661:Vasoconstriction