title: Hydrochlorothiazide-induced pulmonary edema with severe acute myocardial dysfunction.
abstract: A 73-year-old woman presented with acute pulmonary edema and hypotension less than 1 h after taking hydrochlorothiazide 50 mg, a reaction which has been reported as a rare but classic adverse drug response. Though prior cases have supported a noncardiogenic pulmonary edema syndrome, hemodynamic monitoring in this patient demonstrated a refractory low cardiac output state for more than 24 h. In the absence of other etiologies, this represents a new finding.
authors.affiliation: Department of Medicine, Salem Hospital, Oregon, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Frierson
authors.forename: S L
authors.initials: SL
authors.lastname: Marvel
authors.forename: G M
authors.initials: GM
authors.lastname: Thomas
mesh_terms: D000208:Acute Disease; D000368:Aged; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D007022:Hypotension / Q000139:chemically induced; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000503:physiopathology; D018754:Ventricular Dysfunction / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D006852:Hydrochlorothiazide