Calcium signalling in platelets and other nonexcitable cells.
By virtue of their biological simplicity and widespread availability, platelets frequently have been used as a model system to study signal transduction. Such studies have revealed that changes in intracellular free calcium concentration are central to platelet functioning. The following article reviews current concepts of platelet structure and function, with particular emphasis on the mechanisms involved in platelet Ca2+ signalling.
Sargeant
P
P
Physiological Laboratory, Cambridge University, U.K.
Sage
S O
SO
D000818:Animals; D001792:Blood Platelets / Q000502:physiology*; D002118:Calcium / Q000097:blood*; D006801:Humans; D015398:Signal Transduction / Q000502:physiology*
D002118:Calcium