Helical growth of hyphae of Candida albicans.
When grown on a range of surfaces in conditions favouring hyphal growth, hyphae of Candida albicans grew in a right-handed helical fashion. This phenomenon was observed with eight strains and with two nutrient media. It is suggested that this is a result of rotation of the hyphal apex as it extends, which on some surfaces results in a helical hyphal wall, but which in a liquid results in a straight hypha. The consequence is that on a surface, a helically growing hypha will be exposed to a more diverse environment than a straight hypha. This phenomenon may have significance in the colonization of tissue by C. albicans.
Sherwood-Higham
J
J
Department of Molecular and Cell Biology, Marischal College, University of Aberdeen, UK.
Zhu
W Y
WY
Devine
C A
CA
Gooday
G W
GW
Gow
N A
NA
Gregory
D W
DW
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology; D002176:Candida albicans / Q000166:cytology / Q000187:drug effects / Q000254:growth & development*; D002455:Cell Division / Q000187:drug effects; D054714:Echinocandins; D005656:Fungal Proteins; D010455:Peptides; D010456:Peptides, Cyclic / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D054714:Echinocandins; D005656:Fungal Proteins; D010455:Peptides; D010456:Peptides, Cyclic; C042101:cilofungin; C007572:echinocandin B