title: Indocyanine green video-angiographic findings in choroidal osteoma.
abstract: Indocyanine green video-angiography (ICG) was done twice on three patients with choroidal osteoma. Choroidal osteoma consisted of two portions, a yellow-white area and a surrounding orange area. The early phase of ICG angiography showed hypofluorescence due to blockage, corresponding to the osteoma. However, the hypofluorescence was greater in areas corresponding to the orange portions of the lesions than in the yellow-white parts. In the late phase, tumor staining was present, corresponding to the orange area. Although long-standing yellow-white lesions blocked fluorescence in the late phase, some of these showed hyperfluorescence. ICG video-angiography showed areas of blocked fluorescence in the early phase as well as hyperfluorescent areas accompanied by several small hypofluorescent foci in the late phase, corresponding to very slight ophthalmoscopically observed changes in the vicinity of the osteoma. During follow-up observation, fluorescein angiography confirmed the extension of the osteoma into this area. These results confirm that the characteristic findings of choroidal osteoma can be observed with ICG video-angiography. This imaging technique showed the lesions were larger than they appeared with ophthalmoscopy and fluorescein angiography.
authors.affiliation: Department of Ophthalmology, Nihon University, School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yuzawa
authors.forename: A
authors.initials: A
authors.lastname: Kawamura
authors.forename: M
authors.initials: M
authors.lastname: Haruyama
authors.forename: M
authors.initials: M
authors.lastname: Matsui
mesh_terms: D000293:Adolescent; D000328:Adult; D002829:Choroid / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D002830:Choroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D009887:Ophthalmoscopy; D010016:Osteoma / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014741:Video Recording
chemical_list: D007208:Indocyanine Green