Schizophrenia and glutamate receptor genes.
Nine multiplex schizophrenia families were genotyped with polymorphisms for the GLUR5 and NMDAR1 glutamate receptor subunit genes. Using the lod score technique, evidence of linkage was not found assuming either dominant or recessive transmission. Similarly, the non-parametric sib pair test did not yield significant evidence of linkage.
Pariseau
C
C
Department of Psychiatry, University of Utah Medical Center, Salt Lake City 84132.
Gregor
P
P
Myles-Worsley
M
M
Holik
J
J
Hoff
M
M
Waldo
M
M
Freedman
R
R
Coon
H
H
Byerley
W
W
D008040:Genetic Linkage; D006801:Humans; D008126:Lod Score; D018598:Minisatellite Repeats; D008957:Models, Genetic; D009679:Nuclear Family; D017470:Receptors, Glutamate / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*
D017470:Receptors, Glutamate