Occupational PAH exposure: urinary 1-hydroxypyrene levels of coke oven workers, aluminium smelter pot-room workers, road pavers, and occupationally non-exposed persons in Sweden.
Polycyclic aromatic hydrocarbon (PAH) levels in air, and worker urinary 1-hydroxypyrene levels were studied in a coke oven, a Söderberg aluminium smelter pot-room, and during road-paving. Increased PAH exposure was shown to cause increased 1-hydroxypyrene excretion. Road-paving gave low PAH exposure, but resulted in a detectable elevated urinary 1-hydroxypyrene level. Background urinary 1-hydroxypyrene levels in office workers were determined, and a statistically significant difference between smokers and non-smokers was observed. It is suggested that urinary 1-hydroxypyrene can be used as biological exposure index for PAH exposure.
Levin
J O
JO
National Institute of Occupational Health, Research Department in Umeå, Sweden.
Rhén
M
M
Sikström
E
E
D000395:Air Pollutants, Occupational / Q000032:analysis* / Q000652:urine; D000535:Aluminum; D003077:Coke; D006801:Humans; D010578:Petroleum; D011083:Polycyclic Compounds / Q000032:analysis* / Q000378:metabolism; D011721:Pyrenes / Q000378:metabolism*; D013997:Time Factors
D000395:Air Pollutants, Occupational; D003077:Coke; D010578:Petroleum; D011083:Polycyclic Compounds; D011721:Pyrenes; D000535:Aluminum; C033146:1-hydroxypyrene