title: Long-term course of bronchiectasis and bronchiolitis obliterans as late complication of smoke inhalation.
abstract: We describe the long-term course of a patient with bronchiectasis and bronchiolitis obliterans, both of which developed as late complications of a smoke inhalation injury. Sequential chest X-rays obtained during the observation period showed gradual progression of bronchiectasis from the saccular to the cystic type. Symptoms, spirometry and blood gas analysis, however, remained stable for 15 years. We believe that symptoms and physiological derangement were due mainly to bronchiolitis obliterans, and that once the pathophysiological condition had been established following the initial injury, it could be maintained by conservative medical management.
authors.affiliation: Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tasaka
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Fujishima
authors.forename: A
authors.initials: A
authors.lastname: Ishizaka
authors.forename: F
authors.initials: F
authors.lastname: Yamasawa
authors.forename: T
authors.initials: T
authors.lastname: Kawashiro
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001784:Blood Gas Analysis; D001987:Bronchiectasis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D001989:Bronchiolitis Obliterans / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D001999:Bronchoscopy; D002908:Chronic Disease; D006801:Humans; D008297:Male; D012129:Respiratory Function Tests; D015208:Smoke Inhalation Injury / Q000150:complications* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents