[Locoregional recurrences of breast cancer].
OBJECTIVE
To determine the characteristics of 51 cases of isolated local regional breast cancer recurrence.


METHODS
Retrospective study from 1980 to 1992, survival calculated according to Kaplan-Meier and log-rank test.


RESULTS
Twenty-five patients had had a conservative treatment of her primary tumour, 26 had been treated by modified radical mastectomy. Local regional recurrence rate was 9%: 44% of recurrences after lumpectomy and 43% of recurrences after mastectomy occurred within 2 years after the initial treatment. Site of local regional recurrence was chest wall only (16 cases), breast only (15 cases) or axillary or supraclavicular node with or without chest wall or breast involvement (20 cases). The actuarial 5-year survival rate after recurrence is 54%. It depends on the time to recurrence (40% if time to recurrence was less than 2 years, 68% if more than 2 years, p < 0.10), on initial node involvement (36% for N+, 71% for N-, p < 0.15) and on the site of recurrence (chest wall: 43%; breast: 48%; regional node: 12%, p < 0.10).


CONCLUSIONS
Like in the literature, severe recurrences are early recurrences, lymph node recurrences and recurrences following a primary tumour with involved axillary nodes.
Molitor
J L
JL
Service de Médecine Interne-Oncologie, Hôpital Saint-Antoine, Paris.
Demuynck
B
B
Louvet
C
C
Varette
C
C
Marpeau
L
L
de Gramont
A
A
Delfau
S
S
Soubrane
D
D
Pigné
A
A
Barrat
J
J
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000401:mortality* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008408:Mastectomy / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis
Récidives loco-régionales de cancers du sein.