title: Ileus following gynecologic surgery: management with water-soluble hyperosmolar radiocontrast material.
abstract: Postoperative ileus following gynecologic surgery can prolong hospitalization and may predispose patients to mechanical obstruction. Our objective was to study the safety and efficacy of a water-soluble, hyperosmolar, radiocontrast material in the management of postoperative ileus in patients having gynecologic surgery. Of 115 cases, 57 were studied prospectively and received water-soluble radio-opaque contrast material via a nasogastric tube if bowel function had not returned by the third day. Fifty-eight well-matched control cases were managed without this material and received a suppository on the third day. The contrast material was well tolerated. Return of bowel function, day of oral intake, subsequent postoperative recovery, and duration of hospital stay were similar in the two groups. Water-soluble, hyperosmolar, radio-opaque contrast material given on the third postoperative day was safe, but of no apparent clinical benefit in resolving ileus following gynecologic surgery.
authors.affiliation: Department of Obstetrics and Gynecology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Finan
authors.forename: D P
authors.initials: DP
authors.lastname: Barton
authors.forename: J V
authors.initials: JV
authors.lastname: Fiorica
authors.forename: M S
authors.initials: MS
authors.lastname: Hoffman
authors.forename: W S
authors.initials: WS
authors.lastname: Roberts
authors.forename: N
authors.initials: N
authors.lastname: Gleeson
authors.forename: D
authors.initials: D
authors.lastname: Cavanagh
mesh_terms: D001062:Appendectomy; D003287:Contrast Media / Q000627:therapeutic use*; D003973:Diatrizoate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007415:Intestinal Obstruction / Q000209:etiology / Q000628:therapy*; D009994:Osmolar Concentration; D010051:Ovarian Neoplasms / Q000601:surgery; D010052:Ovariectomy; D011183:Postoperative Complications / Q000628:therapy*; D011446:Prospective Studies; D012489:Salpingostomy; D012995:Solubility; D000267:Tissue Adhesions; D002583:Uterine Cervical Neoplasms / Q000601:surgery; D014867:Water
chemical_list: D003287:Contrast Media; D014867:Water; D003973:Diatrizoate