title: Local therapy for mucocutaneous Kaposi's sarcoma in patients with acquired immunodeficiency syndrome.
abstract: BACKGROUND
  Kaposi's sarcoma (KS) accounts for significant morbidity in AIDS patients. Lessons are often numerous, disfiguring, painful, and may interfere with function. Although generalized therapy is available, local treatment is often more desirable.
  
  
  OBJECTIVE
  To summarize the available data on local therapy for KS.
  
  
  METHODS
  Literature was searched using Medline.
  
  
  RESULTS
  Excision, laser destruction, cryotherapy, intralesional chemotherapy, immunotherapy, and radiation therapy were compared for success rate, cost, and convenience.
  
  
  CONCLUSIONS
  Intralesional therapy, cryotherapy, and radiation all have substantial advantages over excision or laser surgery. Choice of the appropriate modality varies with different sites and patients.
authors.affiliation: Department of Dermatology, Jefferson Medical College, Philadelphia, Pennsylvania 19107-5102, USA.
authors.forename: G F
authors.initials: GF
authors.lastname: Webster
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D006801:Humans; D009092:Mucous Membrane; D012514:Sarcoma, Kaposi / Q000150:complications / Q000628:therapy*; D012878:Skin Neoplasms / Q000150:complications / Q000628:therapy*