title: Genetics of drug resistance.
authors.affiliation: Memorial Sloan-Kettering Cancer Center, Laboratory of Cell & Biochemical Genetics, New York, NY 10021.
authors.forename: J L
authors.initials: JL
authors.lastname: Biedler
authors.forename: B A
authors.initials: BA
authors.lastname: Spengler
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000235:genetics / Q000378:metabolism; D000222:Adaptation, Physiological; D000477:Alkylating Agents / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002461:Cell Line, Transformed / Q000187:drug effects; D002945:Cisplatin / Q000494:pharmacology; D006224:Cricetinae; D003412:Cricetulus; D004250:DNA Topoisomerases, Type II / Q000502:physiology; D004351:Drug Resistance / Q000235:genetics*; D018432:Drug Resistance, Multiple / Q000235:genetics; D005493:Folic Acid Antagonists / Q000494:pharmacology; D006801:Humans; D008168:Lung; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics / Q000502:physiology; D059005:Topoisomerase II Inhibitors
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000477:Alkylating Agents; D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists; D059005:Topoisomerase II Inhibitors; D013762:Tetrahydrofolate Dehydrogenase; D004250:DNA Topoisomerases, Type II; D002945:Cisplatin