title: Effect of auriculopalpebral nerve block and intravenous administration of xylazine on intraocular pressure and corneal thickness in horses.
abstract: Intraocular pressure (IOP) was measured, using applanation tonometry, in both eyes of 20 horses after topical application of 0.5% proparacaine to the cornea. Ultrasonic pachymetry was used to measure central, mid-peripheral, and peripheral corneal thickness (CT) in all 4 quadrants of both eyes of 25 horses. All measurements were repeated after auriculopalpebral nerve block, sedation by IV administration of xylazine, or combination of nerve block and sedation. Mean IOP after topical anesthesia of the cornea was 20.6 +/- 4.7 mm of Hg for the left eye and 20.35 +/- 3.7 mm of Hg for the right eye. Mean central CT was 793.2 +/- 42.3 microns. The peripheral part of the cornea was significantly (P < 0.05) thicker, on average, than the central part of the cornea. Auriculopalpebral nerve block had no significant effect on IOP or CT. Intravenous administration of xylazine resulted in a significant (P < 0.05) decrease in IOP, but had no effect on CT.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210, USA.
authors.forename: A
authors.initials: A
authors.lastname: van der Woerdt
authors.forename: B C
authors.initials: BC
authors.lastname: Gilger
authors.forename: D A
authors.initials: DA
authors.lastname: Wilkie
authors.forename: S M
authors.initials: SM
authors.lastname: Strauch
mesh_terms: D000818:Animals; D003315:Cornea / Q000033:anatomy & histology / Q000187:drug effects*; D005260:Female; D006736:Horses / Q000502:physiology*; D007275:Injections, Intravenous; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D009407:Nerve Block / Q000662:veterinary*; D014991:Xylazine / Q000494:pharmacology*
chemical_list: D014991:Xylazine