Asian macaque pepsinogens and pepsins.
Five pepsinogens were purified from the gastric mucosa of eight species of Asian macaques. The chromatographic behavior of each pepsinogen was essentially the same but differed from human and other mammalian pepsinogens. The major pepsinogen in each species was pepsinogen A-1, accounting for 29-48% of the total. Amino acid compositions and some enzymatic properties of derived pepsins were similar for the various monkey species. This high degree of similarity confirms that these species are closely related to one another.
Kageyama
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Department of Cellular and Molecular Biology, Kyoto University, Aichi, Japan.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001208:Asia; D001835:Body Weight; D004795:Enzyme Stability; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology*; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D008251:Macaca / Q000378:metabolism*; D008297:Male; D009929:Organ Size; D010434:Pepsin A / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D010435:Pepsinogens / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D013045:Species Specificity; D013552:Swine
D000596:Amino Acids; D007527:Isoenzymes; D010435:Pepsinogens; D010434:Pepsin A