Effect of implantable nonthoracotomy defibrillation system on permanent pacemakers: an in vitro analysis with clinical implications.
Implantable cardioverter defibrillation systems are capable of delivering over 700 volts, and upwards of 40 joules (J) directly to the heart. Nonthoracotomy lead (NTL) systems allow the delivery of this energy to the inside of the heart, and potentially in close proximity to the leads of an endocardial pacing system. The effect of repeated maximal energy discharges (stored energy 40 J, delivered energy 38 J), utilizing both monophasic as well as biphasic shock pulses delivered via two different configuration NTL systems on a series of Pacesetter polarity programmable present generation single, and dual chamber pacemakers was evaluated in vitro using a saline test tank. All pulse generators studied demonstrated normal function and were not reprogrammed nor adversely affected by repeated defibrillation shocks. The current induced in the leads was assessed, and shown to be as high as 1.5 amps in the proximal conductor and 1.2 amps in the distal conductor of the ventricular lead, which may cause damage at the electrode-myocardial interface, and explain some of the postshock rise in capture and sensing thresholds that have been reported with implanted pacing systems postdefibrillation.
Van Lake
P J
PJ
Pacesetter, Inc., Sylmar, California 91392.
Levine
P A
PA
Mouchawar
G A
GA
D017147:Defibrillators, Implantable; D004567:Electrodes, Implanted; D004867:Equipment Design; D004868:Equipment Failure; D006801:Humans; D008955:Models, Cardiovascular; D008961:Models, Structural; D010138:Pacemaker, Artificial; D013908:Thoracotomy