title: Neurobrucellosis in children.
abstract: Neurobrucellosis is an uncommon disease in children. The authors present two cases of brucellar meningo-encephalitis. Headache and vomiting were the main complaints and one child had also some behavioural disturbance as well as papilloedema and sixth cranial nerve palsy. The clinical diagnosis was suggested by epidemiological data in both cases. Blood and CSF cultures confirmed brucellar aetiology in one of the cases and positive serum and CSF specific antibodies in both. Clinical course was favourable after treatment with doxycycline, rifampicin and streptomycin. No relapse occurred and there were no sequelae.
  
  
  CONCLUSIONS
  Neurobrucellosis should be considered in the differential diagnosis of neurobehavioural disturbance of children living in areas where brucellosis is endemic.
authors.affiliation: Hospital Pediátrico de Coimbra, Portugal.
authors.forename: M H
authors.initials: MH
authors.lastname: Estevão
authors.forename: L M
authors.initials: LM
authors.lastname: Barosa
authors.forename: L M
authors.initials: LM
authors.lastname: Matos
authors.forename: A A
authors.initials: AA
authors.lastname: Barroso
authors.forename: H C
authors.initials: HC
authors.lastname: da Mota
mesh_terms: D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy; D002648:Child; D004318:Doxycycline / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000188:drug therapy; D012293:Rifampin / Q000627:therapeutic use; D013307:Streptomycin / Q000627:therapeutic use
chemical_list: D004318:Doxycycline; D012293:Rifampin; D013307:Streptomycin