title: Treatment of EBV-induced lymphoproliferative disorder with epipodophyllotoxin VP16-213.
abstract: A case of haemophagocytic lymphohistiocytosis consistent with X-linked lymphoproliferative disorder is described. Remission was observed after administration of VP-213, a cytotoxic drug generally used to treat histiocytosis. The child is currently in good clinical health.
authors.affiliation: Department of Paediatrics, University Federico II of Naples, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Migliorati
authors.forename: A
authors.initials: A
authors.lastname: Castaldo
authors.forename: S
authors.initials: S
authors.lastname: Russo
authors.forename: F
authors.initials: F
authors.lastname: Porta
authors.forename: A
authors.initials: A
authors.lastname: Fiorillo
authors.forename: S
authors.initials: S
authors.lastname: Guida
authors.forename: V
authors.initials: V
authors.lastname: Poggi
authors.forename: A
authors.initials: A
authors.lastname: Guarino
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D008040:Genetic Linkage / Q000235:genetics; D004854:Herpesvirus 4, Human; D006801:Humans; D007244:Infectious Mononucleosis / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008099:Liver / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008232:Lymphoproliferative Disorders / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008297:Male; D011034:Podophyllotoxin / Q000627:therapeutic use*; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014960:X Chromosome
chemical_list: D011034:Podophyllotoxin