title: Effect of protein and fat content in feed on plasma alanine-aminotransferase and hepatic fatty infiltration in mink.
abstract: The effect of the content of protein and fat in the feed on the development of fatty infiltration of the liver in the period from weaning until pelting was measured in two groups of male scanblack mink (Mustela vision) fed 20% and 45%, respectively, of metabolizable energy (ME) from protein. Furthermore, plasma activity of alanine-aminotransferase and the content of specifically chosen clinical-chemical variables in the blood were measured. At pelting time in December, the liver weights were absolutely and relatively heavier to body weight and had a considerably higher fat content at 20% of ME from protein than at 45% of ME from protein. From August to pelting time, the activity of alanine-aminotransferase in plasma was higher at a low protein level than at a higher protein level in the feed. It is concluded that the content of protein and fat in the feed affects the incidence of hepatic fatty infiltration in mink. In the growth period, it is possible, based on plasma activity of alanine-aminotransferase, to select animals with histological fatty infiltration of the liver.
authors.affiliation: National Institute of Animal Science, Department For Small Farm Animals, Research Centre Foulum, Tjele, Denmark.
authors.forename: B M
authors.initials: BM
authors.lastname: Damgaard
authors.forename: T N
authors.initials: TN
authors.lastname: Clausen
authors.forename: P
authors.initials: P
authors.lastname: Henriksen
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D000821:Animal Feed; D000818:Animals; D001647:Bile Acids and Salts / Q000097:blood; D004041:Dietary Fats / Q000032:analysis / Q000494:pharmacology*; D004044:Dietary Proteins / Q000032:analysis / Q000494:pharmacology*; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000737:chemistry / Q000473:pathology*; D008297:Male; D008907:Mink / Q000378:metabolism*
chemical_list: D001647:Bile Acids and Salts; D004041:Dietary Fats; D004044:Dietary Proteins; D008055:Lipids; D000410:Alanine Transaminase