The role of eosinophils in the pathogenesis of asthma.
The eosinophil is regarded as a key mediator of the pathology and abnormal physiology of bronchial asthma. Current investigations are directed at understanding how eosinophils are attracted into the respiratory tract and how they bring about the abnormalities characteristic of this disease.
Seminario
M C
MC
Department of Immunology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905.
Gleich
G J
GJ
D000818:Animals; D001249:Asthma / Q000209:etiology* / Q000503:physiopathology; D004804:Eosinophils / Q000502:physiology*; D006801:Humans; D011657:Pulmonary Eosinophilia / Q000503:physiopathology