Autoimmune neutropenia after unrelated bone marrow transplantation.
A 26-year-old male with Ph+ chronic myeloid leukemia, recipient of an HLA-compatible marrow from a matched unrelated donor, showed good platelet engraftment coupled with poor neutrophil recovery. On day +33 the presence of surface-bound anti-neutrophil antibodies was detected by immunofluorescence. At variance with previously reported cases, the WBC count improved without any specific treatment, and the test became negative on day +42.
Tosi
P
P
Istituto di Ematologia L. e A. Seràgnoli, University of Bologna, Italy.
Bandini
G
G
Tazzari
P
P
Raspadori
D
D
Cirio
T M
TM
Rosti
G
G
Bonini
A
A
Conte
R
R
Tura
S
S
D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications*; D016026:Bone Marrow Transplantation / Q000276:immunology*; D006410:Hematopoiesis; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D008297:Male; D009503:Neutropenia / Q000209:etiology*; D013997:Time Factors