[Characteristics of etiology of immediate hypersensitivity in conditions of exposure to infrasound].
The development of immediate hypersensitivity is process strictly specific for given allergen. The reaction with fatal outcome in guinea pigs is reproduced by 80-100%. However, the work has been published recently in which an opportunity to influence the effect of antigen by non-ionizing physical factors was considered. In experiments with 230 guinea pigs the model anaphylactic shock was used. Animals were subjected to infrasound of 10 Hz frequency and 155-160 dB intensity for ten minutes just before antigen introduction. About 50-60% of animals were wrecked under combined sensitizer and infrasound influence. At the same time in control experiments 80-100% of animals were wrecked three minutes after introduction of permitted dose of sensitizer. The experiments under changed conditions as well as series with passive sensitization have shown that the infrasound effect is due to deviations (rejections) in specific part of anaphylactic shock.
Batanov
G V
GV
D000707:Anaphylaxis / Q000209:etiology; D000818:Animals; D006168:Guinea Pigs; D006969:Hypersensitivity, Immediate / Q000209:etiology*; D013016:Sound / Q000009:adverse effects*; D013223:Statistics as Topic; D013997:Time Factors
Osobennosti formirovaniia giperchuvstvitel'nosti nemedlennogo tipa v usloviiakh vozdeĭstviia na organizm infrazvuka.