title: Croton zehntneri: possible central nervous system effects of the essential oil in rodents.
abstract: The effects of essential oil of Croton zehntneri (Euphorbiaceae), orally administered were studied on behavioral parameters using rats and mice. The oil suspension did not modify pentobarbital induced-hypnosis, stereotypic behavior, catalepsy and amphetamine-induced hypermotility. The open-field behaviors were decreased and the minimal convulsant dose of pentylenetetrazole was increased.
authors.affiliation: Department of Pathology, Faculty of Veterinary Medicine and Zootechnique, University of São Paulo, Brazil.
authors.forename: M J
authors.initials: MJ
authors.lastname: Batatinha
authors.forename: H
authors.initials: H
authors.lastname: de Souza-Spinosa
authors.forename: M M
authors.initials: MM
authors.lastname: Bernardi
mesh_terms: D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects*; D001938:Brazil; D002375:Catalepsy / Q000139:chemically induced; D003436:Croton Oil / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010424:Pentobarbital / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D012890:Sleep / Q000187:drug effects; D013239:Stereotyped Behavior / Q000187:drug effects
chemical_list: D000927:Anticonvulsants; D003436:Croton Oil; D000661:Amphetamine; D010424:Pentobarbital; D010433:Pentylenetetrazole