title: ONO-AP-500-02: a non prostanoid prostaglandin I2 mimetic with inhibitory activity against thromboxane synthase.
authors.affiliation: Minase Research Institute, Ono Pharmaceutical Co., LTD, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kondo
authors.forename: K
authors.initials: K
authors.lastname: Machii
authors.forename: M
authors.initials: M
authors.lastname: Narita
authors.forename: A
authors.initials: A
authors.lastname: Kawamoto
authors.forename: S
authors.initials: S
authors.lastname: Yamasaki
authors.forename: N
authors.initials: N
authors.lastname: Hamanaka
mesh_terms: D000085:Acetates / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001792:Blood Platelets / Q000201:enzymology; D002462:Cell Membrane / Q000201:enzymology / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007082:Ileum / Q000378:metabolism; D008297:Male; D009130:Muscle, Smooth / Q000378:metabolism; D010053:Ovary / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D011725:Pyridines / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011982:Receptors, Prostaglandin / Q000378:metabolism; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*; D014599:Uterus / Q000378:metabolism
chemical_list: D000085:Acetates; C093305:ONO AP 500-02; D010975:Platelet Aggregation Inhibitors; D011725:Pyridines; D011982:Receptors, Prostaglandin; D013930:Thromboxane-A Synthase