title: Kennedy's disease: clinical presentation and laboratory diagnosis.
abstract: Kennedy's disease is a form of progressive spinal and bulbar muscular atrophy of adult onset. This paper describes a case of Kennedy's disease and discusses the laboratory diagnosis and the underlying genetic mechanism. Three other neurological diseases, Huntington's disease, myotonic dystrophy and fragile X syndrome, which have similar genetic defects, are also discussed.
authors.affiliation: Department of Neurology, Alfred Hospital, Melbourne.
authors.forename: M W
authors.initials: MW
authors.lastname: Faragher
authors.forename: W T
authors.initials: WT
authors.lastname: Choi
authors.forename: H E
authors.initials: HE
authors.lastname: MacLean
authors.forename: G L
authors.initials: GL
authors.lastname: Warne
authors.forename: J D
authors.initials: JD
authors.lastname: Zajac
mesh_terms: D000368:Aged; D019411:Clinical Laboratory Techniques; D004587:Electrophoresis, Agar Gel; D005091:Exons; D006801:Humans; D008297:Male; D016472:Motor Neuron Disease / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology*; D009154:Mutation; D016133:Polymerase Chain Reaction; D011944:Receptors, Androgen / Q000235:genetics
chemical_list: D011944:Receptors, Androgen