Strength retention of self-reinforced polyglycolide membrane: an experimental study.
Self-reinforced polyglycolide (SR-PGA) devices are stronger than non-reinforced ones. To study the strength retention of SR-PGA membrane, in vitro and in vivo, membranes were either immersed in distilled water at 37 degrees C, or implanted in the subcutis or around the femoral bone of rats. The SR-PGA membranes lost their strength in vitro by 6 wk, while they retained it for 15 wk in vivo due to the fibrous tissue that formed around and inside the implant (biomembrane). This is an advantage when clinical application of the membrane is being considered.
Ashammakhi
N
N
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.
Mäkelä
E A
EA
Vihtonen
K
K
Rokkanen
P
P
Kuisma
H
H
Törmälä
P
P
D000818:Animals; D001704:Biopolymers / Q000737:chemistry*; D003238:Connective Tissue / Q000737:chemistry / Q000473:pathology / Q000648:ultrastructure; D005269:Femur / Q000601:surgery / Q000648:ultrastructure; D008297:Male; D008422:Materials Testing; D008567:Membranes, Artificial; D011100:Polyglycolic Acid / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D014867:Water
D001704:Biopolymers; D008567:Membranes, Artificial; D014867:Water; D011100:Polyglycolic Acid