[Intervention of lidocaine and Astragalus membranaceus on ventricular late potentials].
16 and 22 patients with positive ventricular late potentials (LP) recorded on signal-averaged electrocardiograms (SAECG) were treated with lidocaine 100 mg iv. or Astragalus membranaceus 24 g iv. drip for 2 weeks respectively. As a result, the SAECGs of 2 (12.5%) and 3 (13.6%) of them normalized respectively. Compared with baseline, there were no significant changes in average HFQRSD, LAS and RMS 40 after treatment of lidocaine. HFQRSD and LAS were shortened significantly 115.9 +/- 29.9 vs 125.1 +/- 29.4 ms (P < 0.001); and 44.8 +/- 15.4 vs 52.8 +/- 15.4 ms (P < 0.001), and RMS 40 was enlarged 20.0 +/- 18.6 vs 12.8 +/- 19.0 microV (P < 0.05) only after treatment of Astragalus membranaceus. It is suggested that the duration of LP was shortened.
Shi
H M
HM
Hua Shan Hospital, Shanghai Medical University.
Dai
R H
RH
Fan
W H
WH
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000503:physiopathology*; D027885:Astragalus propinquus; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D009205:Myocarditis / Q000503:physiopathology / Q000821:virology; D014777:Virus Diseases / Q000503:physiopathology
D004365:Drugs, Chinese Herbal; D008012:Lidocaine