title: A dynamic finite element surface model for segmentation and tracking in multidimensional medical images with application to cardiac 4D image analysis.
abstract: This paper presents a physics-based approach to anatomical surface segmentation, reconstruction, and tracking in multidimensional medical images. The approach makes use of a dynamic "balloon" model--a spherical thin-plate under tension surface spline which deforms elastically to fit the image data. The fitting process is mediated by internal forces stemming from the elastic properties of the spline and external forces which are produced form the data. The forces interact in accordance with Lagrangian equations of motion that adjust the model's deformational degrees of freedom to fit the data. We employ the finite element method to represent the continuous surface in the form of weighted sums of local polynomial basis functions. We use a quintic triangular finite element whose nodal variables include positions as well as the first and second partial derivatives of the surface. We describe a system, implemented on a high performance graphics workstation, which applies the model fitting technique to the segmentation of the cardiac LV surface in volume (3D) CT images and LV tracking in dynamic volume (4D) CT images to estimate its nonrigid motion over the cardiac cycle. The system features a graphical user interface which minimizes error by affording specialist users interactive control over the dynamic model fitting process.
authors.affiliation: Department of Computer Science, University of Toronto, ON, Canada.
authors.forename: T
authors.initials: T
authors.lastname: McInerney
authors.forename: D
authors.initials: D
authors.lastname: Terzopoulos
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D002306:Cardiac Volume; D003196:Computer Graphics; D004285:Dogs; D006352:Heart Ventricles / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D007091:Image Processing, Computer-Assisted; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D014057:Tomography, X-Ray Computed; D014584:User-Computer Interface; D016276:Ventricular Function; D016277:Ventricular Function, Left