title: [Cellular and molecular mechanisms of insulin resistance].
abstract: In the submitted review the authors give an account of contemporary knowledge regarding the mechanism of insulin action, including a brief account of pathological conditions associated with insulin resistance. The development of knowledge of problems of insulin resistance syndromes was always very dynamic, and due to the introduction of techniques of molecular biology and genetics at the turn of the eighties and nineties, a further very marked step forward was made. Despite this it will take some time before molecular mechanisms which will confirm (or rule out?) the etiopathogenetic importance of insulin resistance not only for diabetes but also for hypertension, dyslipidaemia, IHD will be revealed.
authors.affiliation: Skupina pre stúdium diabetu a porúch výzivy, Ustav experimentálnej endokrinológie, Slovenská akadémia vied, Bratislava.
authors.forename: E
authors.initials: E
authors.lastname: Seböková
authors.forename: I
authors.initials: I
authors.lastname: Klimes
authors.forename: P
authors.initials: P
authors.lastname: Stolba
mesh_terms: D006801:Humans; D007328:Insulin / Q000502:physiology*; D007333:Insulin Resistance / Q000502:physiology*; D008967:Molecular Biology; D013577:Syndrome
chemical_list: D007328:Insulin
vernacular_title: Celulárne a molekulárne mechanizmy inzulínovej rezistencie.