Changes in taste associated with intravenous administration of pentamidine.
In this pilot study the authors set out to: (a) describe the incidence of taste changes associated with intravenous (i.v.) pentamidine treatment; and (b) determine the factors that are related to making the taste changes better and worse. A convenience sample (N = 18) of adult male outpatients with AIDS participated in this study. One hundred percent of the participants experienced an unpleasant taste after the administration of pentamidine. The largest percentage of patients had a metallic taste (89%, n = 16); while 67% (n = 12) experienced a bitter taste. These data suggest that healthcare providers need to assess for the unpleasant taste associated with i.v. pentamidine and develop appropriate management strategies.
Glover
J
J
Infusion Center, Kaiser Permanente Medical Group, San Francisco, CA, USA.
Dibble
S
S
Miaskowski
C
C
Geibert
R
R
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000328:Adult; D001066:Appetite / Q000187:drug effects; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010419:Pentamidine / Q000008:administration & dosage / Q000009:adverse effects*; D010865:Pilot Projects; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy*; D013651:Taste Disorders / Q000139:chemically induced* / Q000517:prevention & control
D010419:Pentamidine