title: [Directed cleavage of the 16S rRNA molecule at a single internucleotide bond].
abstract: Cleavage of 16S ribosomal RNA (rRNA) from E. coli "hammerhead" type ribozymes as well as by RNAase iI in the presence of "hymeric" (2'-deoxy-F-thymidine containing) oligonucleotides has been studied. The conditions for the cleavage of a desired single internucleotide bond have been found for a large molecule with a very complicated secondary and three-dimensional structure.
authors.forename: S L
authors.initials: SL
authors.lastname: Bogdanova
authors.forename: A I
authors.initials: AI
authors.lastname: Degtiarev
authors.forename: P V
authors.initials: PV
authors.lastname: Baranov
authors.forename: S S
authors.initials: SS
authors.lastname: Dokudovskaia
authors.forename: I N
authors.initials: IN
authors.lastname: Lavrik
authors.forename: O A
authors.initials: OA
authors.lastname: Dontsova
authors.forename: T S
authors.initials: TS
authors.lastname: Oretskaia
authors.forename: I F
authors.initials: IF
authors.lastname: Krynetskaia
authors.forename: Z A
authors.initials: ZA
authors.lastname: Shabarova
authors.forename: A A
authors.initials: AA
authors.lastname: Bogdanov
mesh_terms: D001483:Base Sequence; D002678:Chimera; D004926:Escherichia coli / Q000235:genetics; D006868:Hydrolysis; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000378:metabolism; D012336:RNA, Ribosomal, 16S / Q000737:chemistry / Q000378:metabolism*; D016914:Ribonuclease H / Q000378:metabolism
chemical_list: D009841:Oligonucleotides; D012336:RNA, Ribosomal, 16S; D016914:Ribonuclease H
vernacular_title: Napravlennoe razrezanie molekul 16S rRNK po edinichnoĭ mezhnukleotidnoĭ sviazi.