title: [An attempt to use enalapril in arterial hypertension in patients with juvenile obesity].
abstract: Clinical efficacy of enalapril, a drug belonging to a group of angiotensin-converting enzyme inhibitors, was studied in patients with pubertal juvenile dyspituitarism (juvenile obesity) coursing with arterial hypertension. A reactive increase of plasma renin activity and reduced concentration of plasma aldosterone were revealed. The drug was characterized by a pronounced hypotensive effect. No negative effects on the blood lipid spectrum or carbohydrate metabolism were observed. The study showed that enalapril may be a drug of choice in the treatment of the hypertensive syndrome in patients with juvenile obesity.
authors.forename: E V
authors.initials: EV
authors.lastname: Malygina
authors.forename: G A
authors.initials: GA
authors.lastname: Gerasimov
authors.forename: T M
authors.initials: TM
authors.lastname: Atamanova
mesh_terms: D000293:Adolescent; D000450:Aldosterone / Q000097:blood; D004656:Enalapril / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D009765:Obesity / Q000097:blood / Q000150:complications*; D012083:Renin / Q000097:blood; D013577:Syndrome
chemical_list: D000450:Aldosterone; D004656:Enalapril; D012083:Renin
vernacular_title: Opyt primeneniia énalaprila pri arterial'noĭ gipertenzii u bol'nykh iunosheskim ozhireniem.