title: The Carney complex (myxomas, spotty pigmentation, endocrine overactivity, and schwannomas).
abstract: The Carney complex is a multisystem tumorous disorder that features myxomas (heart, skin, and breast), spotty skin pigmentation (lentigines and blue nevi), endocrine tumors (adrenal, testicular, and pituitary), and peripheral nerve tumors (schwannomas). The condition is transmitted as an autosomal dominant trait. The most serious components of the syndrome are cardiac myxoma and psammomatous melanotic schwannoma. The cutaneous manifestations are a major clue to the disorder.
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Carney
mesh_terms: D004700:Endocrine System Diseases / Q000235:genetics / Q000473:pathology*; D005260:Female; D005799:Genes, Dominant; D006338:Heart Neoplasms / Q000235:genetics / Q000473:pathology; D006801:Humans; D008297:Male; D009232:Myxoma / Q000235:genetics / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000235:genetics / Q000473:pathology; D009442:Neurilemmoma / Q000235:genetics / Q000473:pathology*; D010859:Pigmentation Disorders / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology; D013577:Syndrome