[Biological properties and antigenic interconnection between Tiuleniy and Karshi flaviviruses].
Biological properties of flaviviruses Tyuleny and Karshi, new for the science, were studied. The viruses are highly pathogenic for laboratory animals; they replicate fairly well in primary chick embryo cells and PS cells. BHK-21 cells were found susceptible to replication of Karshi virus. Tyuleny and Karshi viruses were found capable of initiating and maintaining a persistent infection in primary brain cell cultures from suckling Syrian hamsters for at least 3 months. Both the viruses showed cytoproliferative activity in respect of the above cells in tissue cultures. Our data indicate that Tyuleny virus, a member of a separate antigenic group, is more closely related to Japanese encephalitis virus (strain JaGar 01), and Karshi virus to Powassan virus.
L'vov
D K
DK
Loginova
N V
NV
Lebedeva
G A
GA
Deriabin
P G
PG
Parygina
M M
MM
Buŭnitskaia
O B
OB
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D002478:Cells, Cultured; D002642:Chick Embryo; D006224:Cricetinae; D005416:Flavivirus / Q000502:physiology*; D008647:Mesocricetus; D051379:Mice; D012699:Serology; D014779:Virus Replication
D000956:Antigens, Viral
Biologicheskie svoĭstva i antigennye vzaimosviazi flavivirusov tiuleniĭ i karshi.