[Hepatic arterial infusion chemotherapy and embolization in the treatment of hepatic carcinoma].
From September 1988 to Dec. 1991, 160 patients, in moderate and advanced stages of hepatic carcinoma were treated with hepatic arterial infusion chemotherapy and embolization. Among them, 64.3% was of massive type, 26.5% of nodular type and 9.1% of diffuse infiltrating type. In most of the cases, the tumor was rich in blood vasculature. Tumor thrombus in the portal vessels and artero--venous fistula were common. The size of tumors were 3cm to 24cm. Most of the tumors decreased in size after treatment. In 132 pts followed-up for six to fifty-one months the one-year survival rate was 10.8% in the Hepatic Artery Infusion group, and 41.9% in the Hepatic Artery Infusion+Hepatic Artery Embolization Iodized Oil Gelfoam group. The longest survival period was 51 months after initial Hepatic Artery Iodized Oil and Hepatic Artery Embolization. Factors influencing therapeutic effects were; (1) stage of the tumor. (2) tumor thrombus in the portal vein. (3) methods of Hepatic Artery Infusion and Hepatic Artery Embolization. (4) selection of embolic material. (5) development of collateral circulation.
Wang
Z Y
ZY
Department of Diagnostic Radiology, Chinese Academy of Medical Science Peking Union of Medical College, Beijing.
Shi
Z H
ZH
Zai
R Y
RY
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016461:Chemoembolization, Therapeutic; D004317:Doxorubicin / Q000008:administration & dosage; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D007459:Iodized Oil / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009367:Neoplasm Staging; D015996:Survival Rate
D015251:Epirubicin; D016685:Mitomycin; D007459:Iodized Oil; D004317:Doxorubicin