[Histologic examination of slow epiphyseal distraction in the femur of rabbits].
Slow, symmetric epiphyseal distraction of the distal femur has been performed in 30 immature rabbits aged 10 weeks (group 1) and 16 weeks (group 2). Histological examination has been carried out after 2, 4, 12 and 24 weeks of distraction in both groups. In all animals hyperplasia and hypertrophy of the distracted epiphysis and regular remodeling of the bony growth zone were found after 4 weeks of follow-up. No premature closure of the physis has been noted compared to the controls. Histological differences observed were attributed to various, age related biological potential and they resulted from physiological involution.
Kowalski
W
W
Katedry i Kliniki Ortopedii AM, łodzi.
Zwierzchowski
H
H
Koktysz
R
R
D000818:Animals; D001852:Bone Lengthening; D016723:Bone Remodeling / Q000502:physiology; D002146:Bony Callus / Q000473:pathology*; D016267:External Fixators; D005260:Female; D005269:Femur / Q000473:pathology*; D005500:Follow-Up Studies; D006132:Growth Plate / Q000473:pathology*; D006965:Hyperplasia; D006984:Hypertrophy; D008297:Male; D011817:Rabbits
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