Mediastinal tumor and Klinefelter's syndrome.
Klinefelter's syndrome with karyotype 47,XXY in patients with primary extragonadal germ cell tumors rarely occurs. The endocrinology of Klinefelter's syndrome is changed; elevated beta-human choriomic gonadotropin levels are present. Chemotherapy and thoracic surgery brought complete remission in a patient with lung metastases.
Joos
H
H
Department of Urology, General Hospital, Salzburg, Austria.
Frick
J
J
Wessely
K
K
Rittinger
O
O
Moritz
E
E
Dietze
O
O
Galvan
G
G
D000293:Adolescent; D002822:Choriocarcinoma / Q000150:complications* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D018237:Germinoma / Q000150:complications* / Q000556:secondary / Q000628:therapy; D005870:Giant Cell Tumors / Q000150:complications* / Q000556:secondary / Q000628:therapy; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications* / Q000378:metabolism; D008175:Lung Neoplasms / Q000150:complications* / Q000556:secondary / Q000628:therapy; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D012074:Remission Induction; D013724:Teratoma / Q000150:complications* / Q000556:secondary / Q000628:therapy