Acute Physiology and Chronic Health Evaluation II scoring system in acute myocardial infarction: a prospective validation study.
OBJECTIVE
To study the usefulness of the Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring system for prognostication of inhospital mortality in acute myocardial infarction.


METHODS
A prospective validation study.


METHODS
A medical intensive care unit (ICU) at a university hospital.


METHODS
Over a 3-yr period, 2,007 admissions of 1,714 patients with acute myocardial infarction were studied. In readmissions to the medical ICU during the same hospital stay, only the first admission was studied.


RESULTS
Mean age of the patients was 72 +/- 10 yrs. The medical ICU mortality rate was 13% and total hospital mortality rate was 16%. Mean APACHE II score was 11.6 +/- 6.5. There was a close correlation between observed and predicted mortality rates in classes of patients with various APACHE II scores. Observed mortality in patients with scores of 20 to 24 was higher than the predicted mortality (p < .03). In this subgroup, 25% of the patients had a length of stay in the medical ICU of < 8 hrs.


CONCLUSIONS
Inhospital mortality in patients with acute myocardial infarction could be accurately predicted with APACHE II scores. Prognostication was not as good in patients with a length of stay in the medical ICU of < 8 hrs.
Ludwigs
U
U
Medical Intensive Care Unit, Department of Medicine, Södersjukhuset, Stockholm, Sweden.
Hulting
J
J
D018806:APACHE; D000368:Aged; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D017052:Hospital Mortality; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000401:mortality; D011379:Prognosis; D011446:Prospective Studies; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017741:Survivors / Q000706:statistics & numerical data; D013548:Sweden / Q000453:epidemiology