Bone formation as a reaction to hydraulic hydroxyapatite thermal decomposition product used as bone cement in rabbits.
The bone activity of hydroxyapatite thermal decomposition product was evaluated by the amount of new bone formation after implantation into the femur of rabbits. New bone formation was observed to be bonded to the entire adjacent surface of implanted ceramics at the metaphysis in 16 out of 20 specimens 12 weeks after implantation.
Koshino
T
T
Department of Orthopaedic Surgery, Yokohama City University School of Medicine, Japan.
Kubota
W
W
Morii
T
T
D000818:Animals; D001843:Bone Cements; D002130:Calcium Phosphates / Q000009:adverse effects*; D005260:Female; D005269:Femur / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000648:ultrastructure; D006882:Hydroxyapatites / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration / Q000502:physiology*; D019736:Prostheses and Implants; D011817:Rabbits; D011859:Radiography
D001843:Bone Cements; D002130:Calcium Phosphates; D006882:Hydroxyapatites; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous