[A case of probable allergic bronchopulmonary aspergillosis due to Aspergillus niger].
We report a case of probable allergic bronchopulmonary aspergillosis (ABPA) due to Aspergillus niger. An 80-year-old woman was admitted to our hospital because of wheezing, expectoration of a mucous plug and atelectasis of the right lower lobe as seen on a chest X-ray film. The patient had eosinophilia and immediate wheal-and-flare skin reactivity to A. fumigatus. Serum precipitating antibodies against A. niger and elevated serum IgE, however, were absent. Mucus impaction and bronchiectasis were revealed by both bronchoscopy and CT scanning. The mucous plug contained A. niger, numerous eosinophils and Charcot-Leyden crystals. Corticosteroid therapy ameliorated the symptoms and abnormal laboratory findings. Therefore, this was a rare, informative case of probable ABPA due to A. niger associated with a normal level of serum IgE and negative precipitation antibodies against A. niger antigen.
Shimada
T
T
Department of Internal Medicine, Kumamoto National Hospital, Japan.
Matsumura
K
K
D000368:Aged; D000369:Aged, 80 and over; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000382:microbiology*; D001234:Aspergillus niger / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans