title: [Determination of the diagnostic efficacy of the multi-RAST test (Phadiotop) in allergic rhinitis].
abstract: Diagnosis of IgE mediated allergic rhinitis is based on medical history. Prick-test (of the skin) and determination of increased IgE levels by serum (PRIST and RAST) as well as intranasal provocation test. To search the potential diagnostic value of a multi-RAST test (Phadiotop) in serum and nasal fluids, 508 with rhinitis were studied: In 267 patients nasal allergy was confirmed by the above mentioned tests. Phadiotop revealed a sensitivity of 98.1% in serum and 79.0% in nasal fluid. Specificity of Phadiotop was 95.9% in serum and 97.5% in nasal fluid. Our results show that the determination of Phadiotop can be considered as a very sensitive screening test for allergy detection.
authors.affiliation: Departamento de Otorrinolaringología, Ludwig-Maximilians-Universidad de Munich.
authors.forename: J
authors.initials: J
authors.lastname: Bujía
authors.forename: G
authors.initials: G
authors.lastname: Rasp
mesh_terms: D000328:Adult; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000097:blood; D008297:Male; D008875:Middle Aged; D017817:Nasal Lavage Fluid / Q000276:immunology; D009299:Nasal Provocation Tests; D011852:Radioallergosorbent Test / Q000379:methods; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis* / Q000276:immunology; D012680:Sensitivity and Specificity
chemical_list: D007073:Immunoglobulin E
vernacular_title: Determinación de la eficacia diagnóstica de multi-RAST-test (Phadiotop) en la rinitis alérgica.