Heightened sensitivity of the esophagus to radiation in a patient with AIDS.
Esophageal stricture is an uncommon complication in HIV-negative patients treated with radiation to the chest for lung cancer. There have been a number of recent reports on the association of cancer and HIV-positive patients, as well as a greater sensitivity to radiation therapy of the mucous membranes in HIV/AIDS patients. This article reflects a review of the literature on the risk of major complications and morbidity of the esophagus in HIV+/AIDS patients whose chests are treated with radiation for lung cancer. Included is a report of a previously unpublished case of an early and severe esophageal reaction to radiation therapy in an AIDS patient.
Costleigh
B J
BJ
Department of Radiation Oncology and Nuclear Medicine, Hahnemann University Hospital, Philadelphia, Pennsylvania, USA.
Miyamoto
C T
CT
Micaily
B
B
Brady
L W
LW
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D004940:Esophageal Stenosis / Q000209:etiology; D004947:Esophagus / Q000528:radiation effects*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology; D011836:Radiation Tolerance