title: Avid uptake of technetium-99m-HMPAO by an intracranial plasmacytoma during carotid balloon test occlusion.
abstract: A 56-yr-old woman was evaluated for removal of a tumor at the base of the skull. A test to determine the risk of carotid artery sacrifice was performed prior to surgery using carotid balloon occlusion of the left internal carotid artery and 99mTc-HMPAO perfusion scintigraphy during the occlusion. An unusual intense focus of increased uptake was seen at the site of the primary tumor in the left cavernous sinus. The tumor, found to be plasmacytoma at surgery, demonstrated only mild washout from 30 min to 2 hr after administration of 99mTc-HMPAO, with a tumor-to-cerebellum ratio of 1.6 and 1.5, respectively, and a tumor-to-contralateral cranial ratio of 2.5 and 2.4, respectively. Intracranial plasmacytoma shows good response to radiation therapy, and the differentiation of this tumor from other neoplasms is pertinent to the mode of treatment and surgical approach. Technetium-99m-HMPAO SPECT imaging may be a useful tool in distinguishing these tumors from other neoplasms at the base of the skull.
authors.affiliation: Department of Radiology, Mount Sinai School of Medicine, New York, New York, USA.
authors.forename: M
authors.initials: M
authors.lastname: Lorberboym
authors.forename: D
authors.initials: D
authors.lastname: Segal
authors.forename: J
authors.initials: J
authors.lastname: Machac
authors.forename: C
authors.initials: C
authors.lastname: Sen
authors.forename: M
authors.initials: M
authors.lastname: Sacher
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging*; D003250:Constriction; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010091:Oximes; D010579:Petrous Bone / Q000000981:diagnostic imaging; D011859:Radiography; D012888:Skull Neoplasms / Q000000981:diagnostic imaging*; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime