title: [Bacterial infections in hepatic cirrhosis].
abstract: The aim of this work was to study the prevalence of bacterial infections in hospitalized patients with liver cirrhosis and to compare clinical, bacteriological and evolution features of patients with (group 1) and without bacterial infections (group 2). One hundred thirty two hospitalized patients with liver cirrhosis were prospectively studied and 61 episodes of bacterial infections were diagnosed in 52 (27 spontaneous bacterial peritonitis (44.3%), 16 urinary tract infections (26.2%), 10 pneumonias (16.4%), 3 spontaneous bacteremias (4.9%9, and 5 miscellaneous infections (8.2%)). Twenty six percent of infections were nosocomial. Child-Pugh score was 12 +/- 2 in group 1 vs 10 +/- 2 in group 2 (p = 0.047). Sixty five percent of identified microorganisms were gram negative and 61.5% of these were E. coli. Hospital mortality of group 1 was 29% and that of group 2 was 9% (p = 0.002). It is concluded that there is a high prevalence of bacterial infections in hospitalized cirrhotic patients, that is associated to a high mortality.
authors.affiliation: Unidad de Gastroenterología, Universidad Austral de Chile, Hospital de Valdivia.
authors.forename: C
authors.initials: C
authors.lastname: Toledo
authors.forename: C
authors.initials: C
authors.lastname: Flores
authors.forename: M
authors.initials: M
authors.lastname: Sáenz
authors.forename: P
authors.initials: P
authors.lastname: Jiménez
authors.forename: A
authors.initials: A
authors.lastname: Tejero
authors.forename: H
authors.initials: H
authors.lastname: Ibarra
authors.forename: J
authors.initials: J
authors.lastname: León
authors.forename: M
authors.initials: M
authors.lastname: Arce
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000150:complications* / Q000453:epidemiology*; D003428:Cross Infection / Q000150:complications* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies
vernacular_title: Infecciones bacterianas en la cirrosis hepática.