Systemic vasculitis complicating infantile autoimmune enteropathy.
An infant with unexplained sideroblastic anaemia and severe protracted diarrhoea due to autoimmune gut disease is reported. Despite treatment with an exclusion diet and immunosuppressive agents she developed a severe systemic vasculitic illness. Intensive treatment with plasmapheresis resulted in resolution of the vasculitic process but the child subsequently died after overwhelming septicaemia.
Jenkins
H R
HR
Department of Child Health, University of Wales College of Medicine, University Hospital of Wales, Heath Park, Cardiff CF4 4XW.
Jewkes
F
F
Vujanic
G M
GM
D000756:Anemia, Sideroblastic / Q000209:etiology; D001327:Autoimmune Diseases / Q000150:complications* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D007410:Intestinal Diseases / Q000150:complications* / Q000628:therapy; D010956:Plasmapheresis; D018805:Sepsis / Q000209:etiology; D014657:Vasculitis / Q000209:etiology* / Q000628:therapy
D007166:Immunosuppressive Agents