Oxidized LDL induces serotonin release from blood platelets.
Oxidized low-density lipoprotein (LDL) induces a release of serotonin from morphologically resting platelets and shape changed platelets. This suggests that oxidized LDL, a newly reported weak agonist, contributes to atherogenesis and thrombogenesis by stimulating platelets.
Zhao
B
B
Platelet Research Unit, University of Münster, Germany.
Dierichs
R
R
Harrach-Ruprecht
B
B
Winterhorff
H
H
D001792:Blood Platelets / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D008077:Lipoproteins, LDL / Q000494:pharmacology*; D008854:Microscopy, Electron; D012701:Serotonin / Q000378:metabolism*
D008077:Lipoproteins, LDL; D012701:Serotonin