Relapse of tularemia after aminoglycoside therapy: case report and discussion of therapeutic options.
We describe a patient with ulceroglandular tularemia who initially responded to therapy with gentamicin but then clinically relapsed. Ciprofloxacin was subsequently given for 28 days, and the patient was clinically cured. Aminoglycosides have been considered the drugs of choice in the treatment of tularemia; however, potential alternative treatments do exist. We review the English-language literature on this topic.
Risi
G F
GF
Department of Medicine, University of Utah Health Sciences Center, Salt Lake City 84132.
Pombo
D J
DJ
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D012008:Recurrence; D014406:Tularemia / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D002939:Ciprofloxacin