[An anticoagulant from extracts of peony roots: its isolation and properties].
A protein-free anticoagulant preparation displaying anticoagulative but not fibrinolytic activity in vitro was isolated from peony. Electrophoretic, chromatographic, and spectral analyses revealed that this anticoagulant resembles animal heparin: it contains sulfur, carbon, and nitrogen in quantities characteristic of the latter. Plant heparin enhances anticoagulative and fibrinolytic plasma properties and decreases platelet aggregation. It may be used as a harmless and ecologically pure anticoagulant.
Liapina
L A
LA
Novikov
V S
VS
Pastorova
V E
VE
Uspenskaia
M S
MS
Smolina
T Iu
TIu
Liapin
G Iu
GIu
D000818:Animals; D000925:Anticoagulants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006487:Hemostasis / Q000187:drug effects; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D051381:Rats
D000925:Anticoagulants; D010936:Plant Extracts
Antikoagulant iz ékstraktov korneĭ pionov: poluchenie i svoĭstva.