title: Computer supported multimodal bed-side monitoring for neuro intensive care.
abstract: Multimodal monitoring in neuro-intensive care requires computer supported data analysis and archiving. This paper describes a computer system that is able to integrate the results of analysis of intracranial pressure, cerebral perfusion pressure, transcranial Doppler blood flow velocity, jugular bulb oxygen saturation, laser Doppler blood flow, near infrared spectroscopy. A research-oriented software installed in a standard IBM PC equipped with a low-cost analog-to-digital converter allows a broad spectrum of waveform analyses, from calculation of simple mean values to a selective waveform detection and cross-correlation analysis. The architecture for the signal processing algorithm, the principles of system interfacing and data presentation are discussed briefly. Results from two years of multimodal monitoring in neuro-intensive care show that, apart from simple recording of time trends of monitored variables, certain calculated parameters are particularly useful in the continuous assessment of cerebral haemodynamic and compensatory reserves. Such parameters include: transcranial Doppler pulsatility indices, the dependence between blood flow velocity or laser Doppler flux and cerebral perfusion pressure and the correlation coefficient between pulse amplitude and mean intracranial pressure.
authors.affiliation: MRC Cambridge Centre for Brain Repair & Academic Neurosurgical Unit, Addenbrooke's Hospital, UK.
authors.forename: M
authors.initials: M
authors.lastname: Czosnyka
authors.forename: H
authors.initials: H
authors.lastname: Whitehouse
authors.forename: P
authors.initials: P
authors.lastname: Smielewski
authors.forename: P
authors.initials: P
authors.lastname: Kirkpatrick
authors.forename: E P
authors.initials: EP
authors.lastname: Guazzo
authors.forename: J D
authors.initials: JD
authors.lastname: Pickard
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D000703:Analog-Digital Conversion; D001783:Blood Flow Velocity; D001930:Brain Injuries / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D002648:Child; D003199:Computer Systems; D003422:Critical Care; D005260:Female; D006801:Humans; D007427:Intracranial Pressure; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000097:blood; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013055:Spectrophotometry, Infrared; D017585:Ultrasonography, Doppler, Transcranial
chemical_list: D010100:Oxygen