The prognostic significance of hyperploid cells in squamous carcinoma of the uterine cervix treated with radiotherapy.
Smears were obtained from patients undergoing radiotherapy for Stage I-IV squamous cell carcinoma of the cervix. The presence of cells with large or multiple nuclei in smears taken during or not more than 1 month following therapy was found to be associated with a significantly increased risk of early relapse.
Court
J B
JB
Radiation Science Laboratory, Velindre Hospital, Cardiff, Wales, UK.
Salman
S K
SK
Kerby
I J
IJ
D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000401:mortality / Q000473:pathology* / Q000532:radiotherapy*; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000473:pathology; D009367:Neoplasm Staging; D011003:Ploidies; D011882:Radiotherapy, High-Energy; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000235:genetics / Q000401:mortality / Q000473:pathology* / Q000532:radiotherapy*; D014626:Vaginal Smears
D004273:DNA, Neoplasm