[The interaction of phoscarban with the esterases of houseflies and synanthropic cockroaches].
Interactions of phoscarban and its "oxon" with the esterase complex of the house-fly imago and four species of synanthropic cockroaches were studied. Phoscarban and its oxon have a wide spectrum of effects on the esterase complex in cockroaches and flies. These compounds are not specific inhibitors of any of the zones of esterase activity. Their insecticide effect depends on their ability to inhibit both choline esterases, which are responsible for nervous activity, and carboxyl esterases, which are involved in the detoxication of these compounds. We studied the species specificity of the esterase complex, including individual types and fractions, to phoscarban and its oxon in the order Dictyoptera. It was especially distinct for membrane-bound and water-soluble forms of choline esterases.
Eremina
O Iu
OIu
Roslavtseva
S A
SA
Bakanova
E I
EI
Shipov
A E
AE
Genkina
G K
GK
Zhdanova
G V
GV
Mastriukova
T A
TA
Kabachnik
M I
MI
D000818:Animals; D003058:Cockroaches / Q000201:enzymology*; D004347:Drug Interactions; D004591:Electrophoresis, Polyacrylamide Gel; D004950:Esterases / Q000032:analysis / Q000037:antagonists & inhibitors / Q000187:drug effects*; D006793:Houseflies / Q000201:enzymology*; D007306:Insecticides / Q000494:pharmacology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*
D007306:Insecticides; D009943:Organophosphorus Compounds; C093374:phoscarban; D004950:Esterases
Vzaimodeĭstvie foskarbana s ésterazami komnatnykh mukh i sinantropnykh tarakanov.