title: Autoantibodies in scleroderma and tightskin mice.
abstract: There is much evidence to suggest that scleroderma in human patients is caused by a fundamental defect in the immune system. In tightskin mice, the scleroderma syndrome is associated with autoimmunity, particularly autoantibodies interacting with scleroderma target antigens.
authors.affiliation: Mount Sinai Medical Center, New York.
authors.forename: C
authors.initials: C
authors.lastname: Bona
authors.forename: N
authors.initials: N
authors.lastname: Rothfield
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D001324:Autoantigens / Q000276:immunology; D015551:Autoimmunity / Q000276:immunology; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains; D012595:Scleroderma, Systemic / Q000276:immunology*; D013577:Syndrome
chemical_list: D001323:Autoantibodies; D001324:Autoantigens