title: Discovery of a better aspirin.
authors.affiliation: Inflammatory Diseases Research, G.D. Searle and Monsanto Corporate Research, St. Louis, Missouri 63198, USA.
authors.forename: P
authors.initials: P
authors.lastname: Isakson
authors.forename: K
authors.initials: K
authors.lastname: Seibert
authors.forename: J
authors.initials: J
authors.lastname: Masferrer
authors.forename: D
authors.initials: D
authors.lastname: Salvemini
authors.forename: L
authors.initials: L
authors.lastname: Lee
authors.forename: P
authors.initials: P
authors.lastname: Needleman
mesh_terms: D000698:Analgesia; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D001169:Arthritis, Experimental / Q000188:drug therapy; D001241:Aspirin; D002351:Carrageenan; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D015195:Drug Design; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006801:Humans; D007249:Inflammation; D007527:Isoenzymes / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D002351:Carrageenan; D011451:Prostaglandin-Endoperoxide Synthases; D001241:Aspirin