[Cardiac microangiopathy in diabetics].
Diabetes mellitus induces microvascular damage within the myocardium, without coexistent changes in the extramural coronary arteries. Nonenzymatic glucosylation forms the biochemical basis of diabetic microangiopathy, which further causes specific structural changes of the heart muscle. These changes increase left ventricular stiffness and lead to diastolic filling abnormalities, that may be the first sign of diabetic cardiomyopathy. In this review the author discusses the pathogenesis of the microangiopathy of the heart in diabetes and the methods of its early detection.
Beljić
T
T
Klinicki institut za endokrinologiju, dijabetes i bolesti metabolizma, Interna klinika, Klinicki bolnicki centar Zvezdara, Beograd.
D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology*; D003327:Coronary Disease; D048909:Diabetes Complications; D003925:Diabetic Angiopathies; D006801:Humans
Mikroangiopatija u srcu dijabeticara.