Dyskeratosis congenita.
Dyskeratosis congenita is a rare genodermatosis. Malignant deterioration and hematologic complications are well-described features of this syndrome. Correct recognition is essential for proper management. A review of diagnostic considerations and treatment guidelines is presented.
Drachtman
R A
RA
Division of Pediatric Hematology/Oncology, University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School, New Brunswick, USA.
Alter
B P
BP
D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D007971:Leukoplakia / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008297:Male; D009260:Nail Diseases / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011230:Precancerous Conditions / Q000473:pathology*; D011038:Rothmund-Thomson Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy