title: [Cushing's syndrome in pregnancy].
abstract: Active Cushing's syndrome during pregnancy is a rare phenomenon which was so far described in the literature only in 85 women. The authors give an account of a patient who developed Cushing's syndrome during pregnancy and who was delivered during the eighth month of a healthy foetus by caesarean section, afterwards the hypercortisolism associated with hyperaldosteronism was treated by dextrolateral adrenalectomy. In the removed adrenal gland was a cortical adenoma made up of clear cells and cells reminding of the zona glomerulosa. Subsequently the authors summarize data from the literature on the prevalence of different pathogenetic forms of Cushing's syndrome in pregnant women, on the influence of hypercortisolism on mother and foetus, on the optimal diagnosis and therapy of this syndrome during pregnancy.
authors.affiliation: Endokrinologický ústav, L'ubochna.
authors.forename: A
authors.initials: A
authors.lastname: Kreze
authors.forename: E
authors.initials: E
authors.lastname: Spirová
authors.forename: Z
authors.initials: Z
authors.lastname: Putz
authors.forename: J
authors.initials: J
authors.lastname: Danko
authors.forename: J
authors.initials: J
authors.lastname: Visnovský
authors.forename: J
authors.initials: J
authors.lastname: Breza
authors.forename: M
authors.initials: M
authors.lastname: Pauer
authors.forename: B
authors.initials: B
authors.lastname: Renker
mesh_terms: D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy
vernacular_title: Cushingov syndróm v gravidite.