title: SB 209247, a high affinity LTB4 receptor antagonist demonstrating potent antiinflammatory activity.
authors.affiliation: SmithKline Beecham Pharm., King of Prussia, PA 19406, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: Sarau
authors.forename: J J
authors.initials: JJ
authors.lastname: Foley
authors.forename: D B
authors.initials: DB
authors.lastname: Schmidt
authors.forename: M N
authors.initials: MN
authors.lastname: Tzimas
authors.forename: L D
authors.initials: LD
authors.lastname: Martin
authors.forename: R A
authors.initials: RA
authors.lastname: Daines
authors.forename: P A
authors.initials: PA
authors.lastname: Chambers
authors.forename: W D
authors.initials: WD
authors.lastname: Kingsbury
authors.forename: D E
authors.initials: DE
authors.lastname: Griswold
mesh_terms: D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; D000179:Acrylates / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D016718:Arachidonic Acid; D002118:Calcium / Q000097:blood*; D002460:Cell Line; D004487:Edema / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000494:pharmacology; D007249:Inflammation / Q000503:physiopathology*; D007975:Leukotriene B4 / Q000494:pharmacology; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000494:pharmacology; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology*; D018102:Receptors, Leukotriene B4 / Q000037:antagonists & inhibitors*; D014407:Tumor Cells, Cultured
chemical_list: D000179:Acrylates; D000894:Anti-Inflammatory Agents, Non-Steroidal; D006893:Hydroxyeicosatetraenoic Acids; D011725:Pyridines; D018102:Receptors, Leukotriene B4; D007975:Leukotriene B4; D016718:Arachidonic Acid; D009240:N-Formylmethionine Leucyl-Phenylalanine; D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; C093304:Ticolubant; D002118:Calcium