[Effect of atherosclerotic diet containing polyunsaturated omega-3 fatty acids on level of natural antibodies to prostaglandin F2alpha in patients with ischemic heart disease, hyperlipidemia and hypertension].
The hypolipidemic, antiatherogenic and thrombolytic effects and decrease of prostaglandin F2 alpha (PG) excretion were observed in 55 patients suffering from Ischemic heart disease, hyperlipidemia and hypertension fed the antiatherosclerotic diet containing 20 g of eiconol during 55 days. The low initial level of natural antibodies to PGF2 alpha was increased significantly in blood serum. Authors consider that decrease of PGF2 alpha level under diet influence is connected not only with the change of fatty acid composition of cell membranes but also with increasing of natural antibody production.
Pogozheva
A V
AV
Samsonov
M A
MA
Miagkova
M S
MS
Levitskaia
Iu V
IuV
Kondrashov
S Iu
SIu
D000328:Adult; D000368:Aged; D004036:Diet, Atherogenic; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D015237:Dinoprost / Q000097:blood*; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D005260:Female; D005395:Fish Oils / Q000008:administration & dosage*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000178:diet therapy* / Q000276:immunology; D006973:Hypertension / Q000097:blood / Q000178:diet therapy* / Q000276:immunology; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D007113:Immunity, Innate; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000178:diet therapy* / Q000276:immunology
D004042:Dietary Fats, Unsaturated; D015525:Fatty Acids, Omega-3; D005395:Fish Oils; D000960:Hypolipidemic Agents; C089938:eiconol; D015237:Dinoprost
Vliianie protivoateroskleroticheskoĭ diety s vkliucheniem polinenasyshchennykh zhirnykh kislot omega-3 na uroven estestvennykh antitel k prostaglandinu F2alpha u bolńykh ishemicheskoĭ bolezníu serdtsa, giperlipoproteidemieĭ i gipertonicheskoĭ bolezníu.