[Resistance and resistances].
Drug resistance is a frequent clinical event, induced by more than one mechanism. It is intrinsic and/or acquired by tumoral cell population. But the failure of chemotherapy is also associated to intratumoral drug incorporation and altered drug and/or cell metabolism. Prevention of drug resistance needs integration of pharmacokinetic, biochemical and pathological characteristics of tumoral cell population.
Cappelaere
P
P
Centre Oscar-Lambret, Lille, France.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D012106:Research
D000970:Antineoplastic Agents
Résistance et résistances.