title: [A case of chest wall tumor associated with production of CA125 treated effectively by chemotherapy].
abstract: A 61-year-old female was admitted to our hospital because of a mass in right lateral chest wall and chest pain. Chest X-P and CT scans showed a right chest wall tumor and pleural effusion. Biopsy specimen from the chest wall tumor revealed an adenocarcinoma, not a mesothelioma, based on immunohistochemical study. Cancer cells were also detected in pleural effusion. Imaging diagnostic analysis could detect no primary tumor in lung field or other organs. High levels of CA125 were noticed: 9,610 U/ml in serum and 37,600 U/ml in pleural effusion, respectively. Finally, there was a possibility that the chest wall tumor might be a metastatic lesion from undetected ovarian cancers, so three cycles of combined chemotherapy (CDDP+ADM+CPA) were done. CDDP plus OK-432 was also injected two times intrapleurally. After chemotherapy, the chest wall tumor and effusion disappeared and the serum CA125 level decreased to the normal range.
authors.affiliation: Dept. of Respiratory Medicine, Komatsushima Red Cross Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Akiyama
authors.forename: H
authors.initials: H
authors.lastname: Kondo
authors.forename: S
authors.initials: S
authors.lastname: Kimura
authors.forename: Y
authors.initials: Y
authors.lastname: Fujii
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000276:immunology; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018394:CA-125 Antigen / Q000096:biosynthesis*; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008875:Middle Aged; D010844:Picibanil / Q000008:administration & dosage; D012074:Remission Induction; D013899:Thoracic Neoplasms / Q000188:drug therapy* / Q000276:immunology
chemical_list: D018394:CA-125 Antigen; D010844:Picibanil; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin