title: [Mortality due to bronchopulmonary cancers in workers of 2 foundries].
abstract: A mortality study was carried out in two factories producing stainless steel in order to assess lung cancer risk among workers employed in coke oven, blast and open hearth furnaces, foundry, electric furnace, hot and cold rolling mills and pickling areas. Occupational exposures of interest were chromium compounds, nickel compounds, polycyclic aromatic hydrocarbons (PAH), silica and asbestos. All male workers having at least one year of employment between 01.01.1960 and 31.12.1990 were followed up for mortality. The vital status was assessed from birth place registries. Complete job histories since date of first employment were abstracted from the company files. The smoking habits of 50% of the cohort members were known from medical records. The observed number of deaths (obs) were compared with the expected ones based on regional rates with adjustment for age, sex and calendar time (Standardized Mortality Ratio, SMR). The cohorts included 6324 (factory 1) and 5270 (factory 2) workers. The overall mortality did not differ markedly from that expected in both factories: SMR = 0.95 (obs = 1540, p = 0.05) in factory 1 and SMR = 1.06 (obs = 916, non-significant) in factory 2. SMRs for lung cancer did not differ from unity, respectively 0.99 (obs = 105) and 1.00 (obs = 54), in whole cohorts. Non-significant lung cancer excesses were observed among workers of some workshops where exposures of interest might have occurred: coke oven (SMR = 2.04), blast furnace (SMR = 1.36), open hearth furnace (SMR = 1.75), hot rolling mills (SMR = 1.29). These processes, however, are no longer involved in the study factories. Furthermore, no lung cancer excess was observed among workers employed in current workshops: electric furnaces and cold rolling mills.
authors.affiliation: Institut National de Recherche et de Sécurité, Service d'Epidémiologie, Vandoeuvre.
authors.forename: J J
authors.initials: JJ
authors.lastname: Moulin
authors.forename: M
authors.initials: M
authors.lastname: Lafontaine
authors.forename: B
authors.initials: B
authors.lastname: Mantout
authors.forename: A
authors.initials: A
authors.lastname: Belanger
authors.forename: M
authors.initials: M
authors.lastname: Michel
authors.forename: P
authors.initials: P
authors.lastname: Wild
authors.forename: T
authors.initials: T
authors.lastname: Clavel
authors.forename: M
authors.initials: M
authors.lastname: Fournier
authors.forename: J M
authors.initials: JM
authors.lastname: Fontana
mesh_terms: D000328:Adult; D001194:Asbestos / Q000009:adverse effects; D001984:Bronchial Neoplasms / Q000139:chemically induced / Q000209:etiology / Q000401:mortality*; D002423:Cause of Death; D017608:Chromium Compounds / Q000009:adverse effects; D015331:Cohort Studies; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced / Q000209:etiology / Q000401:mortality*; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects; D009784:Occupational Diseases / Q000401:mortality*; D016273:Occupational Exposure; D011083:Polycyclic Compounds / Q000009:adverse effects; D012907:Smoking; D013193:Stainless Steel; D013997:Time Factors
chemical_list: D017608:Chromium Compounds; D011083:Polycyclic Compounds; D013193:Stainless Steel; D001194:Asbestos; D009532:Nickel
vernacular_title: La mortalité par cancers broncho-pulmonaires parmi les salariés de deux usines sidérurgiques.