Eosinophilic pustular folliculitis in three atopic children with hypersensitivity to Dermatophagoides pteronyssinus.
Three children will be described who present recurrent episodes of pruritic papulopustular follicular lesions on the face, the extremities and the trunk. The episodes lasted for 1-3 months with intermittent remission. Each flare was accompanied by hypereosinophilia and an increased total IgE titer. RAST and prick tests were positive for Dermatophagoides pteronyssinus (DPT). Laboratory tests disclosed no infectious or parasitic etiology. Histological examination showed eosinophilic pustular folliculitis (EPF) in each of the 3 cases. The lesions responded well to topical corticosteroids. The aim of this article is to underline the importance of hypersensitivity reactions (in these particular cases to DPT) in the pathogenesis of EPF.
Boone
M
M
Clinic of Dermatology, University Hospital Saint-Pierre, University of Brussels, Belgium.
Dangoisse
C
C
André
J
J
Sass
U
U
Song
M
M
Ledoux
M
M
D000293:Adolescent; D000485:Allergens; D000818:Animals; D039741:Antigens, Dermatophagoides; D002648:Child; D002675:Child, Preschool; D017449:Dermatitis, Allergic Contact / Q000276:immunology / Q000473:pathology*; D003876:Dermatitis, Atopic / Q000276:immunology / Q000473:pathology*; D004802:Eosinophilia; D005499:Folliculitis / Q000276:immunology / Q000473:pathology*; D005500:Follow-Up Studies; D006023:Glycoproteins; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D008297:Male; D008925:Mites; D012008:Recurrence; D012882:Skin Tests
D000485:Allergens; D039741:Antigens, Dermatophagoides; D006023:Glycoproteins; D007074:Immunoglobulin G; D007073:Immunoglobulin E