title: Positron emission tomography and central neurotransmitter systems in movement disorders.
abstract: This article discusses the anatomical and neurochemical structure of the basal ganglia and reviews the Positron Emission Tomographic (PET) ligands available for investigating these pathways. We discuss how clinical PET studies have improved our understanding of the neurochemical changes underlying principal movement disorders.
authors.affiliation: MRC Cyclotron Unit, Hammersmith Hospital, London, UK.
authors.forename: R A
authors.initials: RA
authors.lastname: Weeks
authors.forename: D J
authors.initials: DJ
authors.lastname: Brooks
mesh_terms: D001479:Basal Ganglia / Q000000981:diagnostic imaging*; D004298:Dopamine / Q000378:metabolism; D006801:Humans; D006816:Huntington Disease / Q000000981:diagnostic imaging; D007980:Levodopa / Q000378:metabolism; D009069:Movement Disorders / Q000000981:diagnostic imaging*; D010300:Parkinson Disease / Q000000981:diagnostic imaging; D011954:Receptors, Dopamine / Q000032:analysis* / Q000502:physiology; D011963:Receptors, GABA-A / Q000032:analysis; D011957:Receptors, Opioid / Q000032:analysis; D014055:Tomography, Emission-Computed; D005879:Tourette Syndrome / Q000000981:diagnostic imaging
chemical_list: D011954:Receptors, Dopamine; D011963:Receptors, GABA-A; D011957:Receptors, Opioid; D007980:Levodopa; D004298:Dopamine