Young maternal age and congenital malformations: a population-based study.
This study examined the prevalence of congenital malformations across the maternal age spectrum and identified specific malformation types that contributed to the overall prevalence among mothers under the age of 20 years. Data were derived from the California Birth Defects Monitoring Program for 1983 through 1988 live births. The distribution of prevalences of all nonchromosomal malformations was U-shaped across maternal age. Furthermore, several specific malformation types, representing nearly every organ system, were elevated among the infants of women under 20 years of age in comparison with those of women 25 to 29 years old.
Croen
L A
LA
March of Dimes Birth Defects Foundation, Emeryville, Calif, USA.
Shaw
G M
GM
D000293:Adolescent; D000328:Adult; D002140:California / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000453:epidemiology*; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D015995:Prevalence; D012307:Risk Factors