[Interleukin-6 and other cytokines in the aqueous humor in uveitis and endophthalmitis].
We studied aqueous humour and serum level of 4 cytokines during uveitis and endophthalmitis: Interleukin 6, Gamma interferon, tumor necrosis factor and Granulocyte-macrophage colony stimulating factor. High levels of IL-6 were found in aqueous humour during ocular inflammation and infection. This elevation of IL-6 level was more constant and more important in the endophthalmitis group (mean level 2.992 pg/ml) than in the uveitis group (mean level 1.480 pg/ml). During endophthalmitis no evident relation was found between IL-6 level and clinical course or aspect, or bacteriological results of anterior chamber tapes. In the uveitis group, no relation was found between IL-6 level and clinical aspect or aetiology.
Feys
J
J
Service d'Ophtalmologie, Centre Hospitalier Intercommunal, Villeneuve-Saint-Georges.
Emond
J P
JP
Salvanet-Bouccara
A
A
Dublanchet
A
A
D001082:Aqueous Humor / Q000737:chemistry*; D001707:Biopsy, Needle; D016207:Cytokines / Q000032:analysis* / Q000502:physiology; D009877:Endophthalmitis / Q000097:blood / Q000382:microbiology / Q000503:physiopathology*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000032:analysis; D006801:Humans; D007371:Interferon-gamma / Q000032:analysis; D015850:Interleukin-6 / Q000032:analysis* / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis; D014605:Uveitis / Q000097:blood / Q000382:microbiology / Q000503:physiopathology*
D016207:Cytokines; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma; D016178:Granulocyte-Macrophage Colony-Stimulating Factor
Interleukine-6 et autres cytokines dans l'humeur aqueuse au cours d'uvéites et d'endophtalmies.