title: Discrimination of Hb D Los Angeles (B121 Glu-Gln) and Hb Beograd (B121 Glu-Val) by dual restriction enzyme analysis.
abstract: Hb D Los Angeles (B121 Glu-Gln) and Hb Beograd (B121 Glu-Val) can be identified by different techniques. Here we describe a dual restriction enzyme digestion protocol (EcoR IG AATTC) and Tsp509 I ( AATT) for the discrimination of these variants.
authors.affiliation: Pediatric Hematology and Molecular Pathology Department, Ankara University, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Akar
authors.forename: A
authors.initials: A
authors.lastname: Ozden
authors.forename: E
authors.initials: E
authors.lastname: Akar
authors.forename: S
authors.initials: S
authors.lastname: Cin
authors.forename: A
authors.initials: A
authors.lastname: Arcasoy
mesh_terms: D001483:Base Sequence; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D015183:Restriction Mapping; D017421:Sequence Analysis
chemical_list: D006455:Hemoglobins, Abnormal