title: Delayed hypersensitivity reaction after infusion of nonionic intravenous contrast material for an excretory urogram: a case report and review of the literature.
abstract: Delayed adverse reactions to ionic and nonionic intravenous contrast media have been reported previously. We report a case in which delayed hypersensitivity to iohexol, a nonionic intravenous contrast agent commonly used in excretory urography, resulted in a bi-phasic allergic response. This reaction consisted of a mild post-infusion episode of urticaria, which preceded and was clinically distinct from a moderately severe dermatological eruption. The episode of urticaria was self-limited. The dermatological reaction was treated successfully with antihistamine therapy.
authors.affiliation: Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Stovsky
authors.forename: A D
authors.initials: AD
authors.lastname: Seftel
authors.forename: M I
authors.initials: MI
authors.lastname: Resnick
mesh_terms: D000368:Aged; D003287:Contrast Media / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D007472:Iohexol / Q000009:adverse effects*; D008297:Male; D013997:Time Factors; D014567:Urography; D014581:Urticaria / Q000139:chemically induced
chemical_list: D003287:Contrast Media; D007472:Iohexol