title: [Biological properties and antigenic interconnection between Tiuleniy and Karshi flaviviruses].
abstract: Biological properties of flaviviruses Tyuleny and Karshi, new for the science, were studied. The viruses are highly pathogenic for laboratory animals; they replicate fairly well in primary chick embryo cells and PS cells. BHK-21 cells were found susceptible to replication of Karshi virus. Tyuleny and Karshi viruses were found capable of initiating and maintaining a persistent infection in primary brain cell cultures from suckling Syrian hamsters for at least 3 months. Both the viruses showed cytoproliferative activity in respect of the above cells in tissue cultures. Our data indicate that Tyuleny virus, a member of a separate antigenic group, is more closely related to Japanese encephalitis virus (strain JaGar 01), and Karshi virus to Powassan virus.
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
authors.forename: N V
authors.initials: NV
authors.lastname: Loginova
authors.forename: G A
authors.initials: GA
authors.lastname: Lebedeva
authors.forename: P G
authors.initials: PG
authors.lastname: Deriabin
authors.forename: M M
authors.initials: MM
authors.lastname: Parygina
authors.forename: O B
authors.initials: OB
authors.lastname: Buŭnitskaia
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D002478:Cells, Cultured; D002642:Chick Embryo; D006224:Cricetinae; D005416:Flavivirus / Q000502:physiology*; D008647:Mesocricetus; D051379:Mice; D012699:Serology; D014779:Virus Replication
chemical_list: D000956:Antigens, Viral
vernacular_title: Biologicheskie svoĭstva i antigennye vzaimosviazi flavivirusov tiuleniĭ i karshi.