Mechanisms of enzymatic glycoside hydrolysis.
The determination of a large number of three-dimensional structures of glycosidases, both free and in complex with ligands, has provided valuable new insights into glycosidase catalysis, especially when coupled with results from studies of specifically labelled glycosidases and kinetic analyses of point mutants.
McCarter
J D
JD
Department of Chemistry, University of British Columbia, Vancouver, Canada.
Withers
S G
SG
D000818:Animals; D001665:Binding Sites; D006026:Glycoside Hydrolases / Q000737:chemistry / Q000378:metabolism*; D006801:Humans
D006026:Glycoside Hydrolases