title: [The sheep: an animal model for ligament prostheses?].
abstract: Ruptures of the anterior cruciform ligament is difficult to repair. Ligament prostheses are sometimes useful. We tested a ligament prosthesis which had the original property of combining a polyester braid with a matrix favouring collagen ingrowth. We implanted this prosthesis in the knee joint of 10 sheep after sectioning the anterior cruciform ligament at it origin. The ligaments were recovered after 6 months. We studied the functional and radiographic results. Tolerance was studied in samples of the articular fluid and synovial tissue. We evaluated bone attachment and fibrous growth using micro-radiography and specific coloration techniques. Samples were examined under electron microscope. No rupture was encountered. We observed a satisfactory functional and radiographic result. No intolerance was observed. The neoligament had a bony or mixed attachment in 60% of the cases and was comprised of oriented tissue in 90% of the cases. Vascular invasion was important. These findings are promising and suggest that long-term studies should be undertaken.
authors.affiliation: Laboratoire de Recherche sur les Matériaux d'intérêt biologique, CNRS EP59, Nantes.
authors.forename: D
authors.initials: D
authors.lastname: Huguet
authors.forename: A
authors.initials: A
authors.lastname: Faintreny
authors.forename: D
authors.initials: D
authors.lastname: Mazui
authors.forename: G
authors.initials: G
authors.lastname: Daculsi
authors.forename: N
authors.initials: N
authors.lastname: Passuti
authors.forename: E
authors.initials: E
authors.lastname: Agado
mesh_terms: D000818:Animals; D005109:Extracellular Matrix; D007595:Joint Prosthesis; D008023:Ligaments, Articular / Q000601:surgery*; D011093:Polyethylene Terephthalates; D012756:Sheep; D013997:Time Factors
chemical_list: D011093:Polyethylene Terephthalates
vernacular_title: Le mouton: modèle animal pour les prothèses ligamentaires?