Scanning electron microscope observation of adherence of Candida albicans to cultured keratinocytes.
The role of antigen 6 in the adherence process of Candida albicans serotype A to cultured keratinocytes was examined with a scanning electron microscope. The number of adhered organisms was significantly lower for the antigen 6-deficient mutant strain than for the antigen 6-positive parent strain (P < 0.001). Fibril- or strand-like structures bridging the organisms and the keratinocytes were found to develop during the later stages of adherence.
Bramono
K
K
Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan.
Tsuboi
R
R
Murai
M
M
Miyakawa
Y
Y
Fukazawa
Y
Y
Ogawa
H
H
D001422:Bacterial Adhesion; D002176:Candida albicans / Q000502:physiology / Q000648:ultrastructure*; D002448:Cell Adhesion / Q000502:physiology; D002478:Cells, Cultured; D006801:Humans; D015603:Keratinocytes / Q000502:physiology / Q000648:ultrastructure*; D008297:Male; D008855:Microscopy, Electron, Scanning