[The influence of vitamin A on production of oxygen free radicals and activity of granulocyte catalase in patients with chronic bronchitis].
The effect of vitamin A on granulocyte chemiluminescence (CT) and catalase activity was studied in 16 patients with COPD. The results obtained show a significant decrease of CL and a significant increase of granulocyte CT activity after incubation with vitamin A, particularly in nonsmoking subjects. This study showed a significant decrease of CT activity after incubation of granulocyte with hydralazine both in cigarette smokers or nonsmokers.
Jankowska
R
R
Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM we Wrocławiu.
Passowicz-Muszyńska
E
E
Banaś
T
T
Marcinkowska
A
A
Medrala
W
W
D000111:Acetylcysteine / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D002374:Catalase / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D005609:Free Radicals / Q000276:immunology; D006098:Granulocytes / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D006830:Hydralazine / Q000494:pharmacology; D007111:Immunity, Cellular / Q000187:drug effects; D008163:Luminescent Measurements; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000032:analysis; D012907:Smoking / Q000009:adverse effects; D014801:Vitamin A / Q000494:pharmacology*
D005609:Free Radicals; D014801:Vitamin A; D006830:Hydralazine; D009240:N-Formylmethionine Leucyl-Phenylalanine; D002374:Catalase; D000111:Acetylcysteine
Wpływ witaminy A na wytwarzanie wolnych rodników tlenowych i aktywność katalazy granulocytów u chorych na przewlekłe zapalenie oskrzeli.