Relationship between Helicobacter pylori and atrophic gastritis.
OBJECTIVE
To investigate the relationship between Helicobacter pylori and atrophic gastritis.


METHODS
The extent of atrophic gastritis was assessed endoscopically in 97 non-ulcer patients, and their H. pylori status was assessed by enzyme-linked immunosorbent assay.


RESULTS
The prevalence of H. pylori infection was greatest in the early stages of atrophic gastritis. Small numbers of H. pylori-negative patients were identified at different stages during the extension of atrophic gastritis.


CONCLUSIONS
H. pylori infection precedes the extension of atrophic gastritis, and a minority of patients with atrophic gastritis may never have been infected with H. pylori.
Satoh
K
K
Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
Kimura
K
K
Yoshida
Y
Y
Ota
Y
Y
Taniguchi
Y
Y
Kihira
K
K
Kasano
T
T
Takimoto
T
T
Suzuki
T
T
Seki
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D005757:Gastritis, Atrophic / Q000097:blood / Q000382:microbiology* / Q000473:pathology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D010435:Pepsinogens / Q000097:blood
D000907:Antibodies, Bacterial; D010435:Pepsinogens