A single-injection, two-sample method for measuring renal 99mTc-MAG3 clearance in both children and adults.
We present a method for estimating 99mTc-MAG3 clearance from both a single injection and two blood samples that is valid for both adults and children. It was obtained by fitting a scaled two-compartment model (having only two adjustable parameters) to adult and pediatric data from multiple centers.
Russell
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Division of Nuclear Medicine, University of Alabama Hospital, Birmingham 35233-6835, USA.
Taylor
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Dubovsky
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Eshima
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D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007668:Kidney / Q000378:metabolism*; D008657:Metabolic Clearance Rate; D017263:Technetium Tc 99m Mertiatide / Q000493:pharmacokinetics*; D016284:Technetium Tc 99m Pentetate / Q000493:pharmacokinetics
D017263:Technetium Tc 99m Mertiatide; D016284:Technetium Tc 99m Pentetate