title: [A case of pulmonary hyalinizing granuloma with its occupational history of dust exposure].
abstract: Multiple pulmonary nodules were found in a patient who had an occupational history of coal mining for eleven years and road construction for fifteen years. An open lung biopsy was performed, because nodules had increased in size compared to previous ones and a trasbronchial biopsy was not diagnostic. The nodules were composed of dense concentric lamellar collagenous structures with a serpentine pattern surrounded by an infiltration of histiocytes, lymphocytes and plasma cells with Russel bodies. These findings are compatible with pulmonary hyalinizing granuloma (PHG) named by Liebow A. A. The etiopathogenetic mechanism and the difference between PHG and silicotic nodule is discussed.
authors.affiliation: Division of Respiratory Disease, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kido
authors.forename: A
authors.initials: A
authors.lastname: Kajiki
authors.forename: N
authors.initials: N
authors.lastname: Nagata
authors.forename: H
authors.initials: H
authors.lastname: Manabe
authors.forename: Y
authors.initials: Y
authors.lastname: Iwata
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D004391:Dust / Q000009:adverse effects; D006099:Granuloma / Q000175:diagnosis*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis*; D008297:Male; D009784:Occupational Diseases / Q000175:diagnosis*; D012829:Silicosis / Q000175:diagnosis
chemical_list: D004391:Dust