Diabetic fibrous breast disease: a clinical entity that mimics cancer.
Three typical cases of fibrous mastopathy associated with diabetes mellitus are described. The histological change is a connective-tissue overgrowth with vasculitis and some proliferation of duct epithelium. The clinical changes are indistinguishable by physical or radiographic findings from malignancy. In young patients with long-standing diabetes the presence of one or more suspicious clinical and imaging findings can suggest the presence of this lesion but a surgical biopsy or, at least, a close follow-up is required.
Pluchinotta
A M
AM
Department of Surgery, University Hospital of Padua, Italy.
Talenti
E
E
Lodovichetti
G
G
Tiso
E
E
Biral
M
M
D000328:Adult; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis* / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D005355:Fibrosis; D006801:Humans