Biotypes of oral Candida albicans isolates in human immunodeficiency virus-infected patients from diverse geographic locations.
Oral Candida albicans isolates from HIV-infected individuals in Hong Kong, Australia, Germany and England were characterised using a biotyping system based on enzyme profiles, carbohydrate assimilation patterns and boric acid resistance of the yeasts. A total of 44 biotypes were found amongst the 117 oral C. albicans isolates examined. The major biotype A1R accounted for 17.9% of all isolates while the second commonest biotype was A1S (11.1% of isolates). Whereas these two biotypes were isolated from all the regions studied, there were a number of other biotypes unique to individual countries. The data indicate that there are many different sub-strains of oral C. albicans in HIV-infected patients, some of which are globally prevalent. However, further work is required to ascertain the diversity of oral C. albicans biotypes, if any, in health and disease.
Tsang
P C
PC
Oral Biology Unit, University of Kong.
Samaranayake
L P
LP
Philipsen
H P
HP
McCulloug
M
M
Reichart
P A
PA
Schmidt-Westhausen
A
A
Scully
C
C
Porter
S R
SR
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D001315:Australia / Q000453:epidemiology; D002176:Candida albicans / Q000145:classification*; D002180:Candidiasis, Oral / Q000453:epidemiology / Q000382:microbiology*; D004739:England / Q000453:epidemiology; D005858:Germany / Q000453:epidemiology; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D016533:Mycological Typing Techniques