[Histologic changes in ligated stumps of ovarian blood vessels in preoperative low-molecular weight preventive heparin administration].
OBJECTIVE
Thrombotic changes and vascular lesions during adnexectomy were observed. We resected the stumps of the ovarian blood vessels after 30 min.


METHODS
Two hours before surgery we injected a dosis of 20 mg Lovenox s.c. Special histological methods of coloring were used.


RESULTS
We found evidence of only parietal thrombus formation 3 times (10%) in the arteries and 4 times (13.3%) in the veins; the endothelial damage was reduced.


CONCLUSIONS
Low-molecular-weight heparin is most effective and safe in the prevention of thrombogenesis. We definitively replaced the "old" standard heparin in clinical gynecological practice.
Slunsky
R
R
Abteilung für Frauenheilkunde, Krankenhaus Klosterneuburg, Osterreich.
D004730:Endothelium, Vascular / Q000473:pathology; D017984:Enoxaparin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007279:Injections, Subcutaneous; D008026:Ligation; D010052:Ovariectomy; D010053:Ovary / Q000098:blood supply*; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control*; D011292:Premedication; D013927:Thrombosis / Q000473:pathology / Q000517:prevention & control*
D017984:Enoxaparin
Histologische Veränderungen in den unterbundenen Stümpfen der Ovarialgefässe bei präoperativer niedermolekularer Heparinprophylaxe.