Retinoids and ageing.
The observation that topical retinoic acid could attenuate wrinkles and other features of skin photoageing has projected this molecule into the media spotlight. Behind this effect are in fact major basic biological issues related to the role of retinoids in tissue maintenance and their possible interference with the molecular biology of cellular ageing.
Saurat
J H
JH
Department of Dermatology, University Canton Hospital, Geneva, Switzerland.
D000375:Aging / Q000502:physiology*; D003600:Cytosol / Q000378:metabolism; D006801:Humans; D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D018168:Receptors, Retinoic Acid / Q000378:metabolism; D012176:Retinoids / Q000378:metabolism*; D014801:Vitamin A / Q000378:metabolism
D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear; D018168:Receptors, Retinoic Acid; D012176:Retinoids; D014801:Vitamin A