[Maternal effect of the mutagen-sensitive mutation mus(2)201G1 on mutagenesis in Drosophila melanogaster spermatozoid genome, induced by ethylene imine and methylmethane sulfonate].
The frequency of recessive sex-linked lethal mutations (RSLLM) induced in chromosome Muller-5 of mature sperms by treatment with ethyleneimine (EI) or methyl methanesulfonate (MMS) was shown to increase when male pronucleus or zygote was formed in the oocyte cytoplasm of the mutagen-sensitive line mus(2)201G1. The increase in the total number of mutations in the mutant cytoplasm was accompanied by a transformation of damages causing mosaic mutations into damage to the genome, which are recorded as complete mutations.
Shvartsman
P Ia
PIa
Romashkina
T B
TB
D000818:Animals; D001388:Aziridines / Q000633:toxicity*; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D018392:Genomic Imprinting; D015698:Genomic Library; D008297:Male; D008741:Methyl Methanesulfonate / Q000633:toxicity*; D009030:Mosaicism; D009035:Mothers; D009153:Mutagens / Q000633:toxicity*; D009154:Mutation; D013094:Spermatozoa / Q000187:drug effects*
D001388:Aziridines; D009153:Mutagens; C033132:aziridine; D008741:Methyl Methanesulfonate
Materinskoe vliianie mutagenchuvstvitel'noĭ mutatsii mus(2)201G1 na indutsirovannyĭ étileniminom i metilmetansul'fonatom mutagenez v genome spermatozoidov Drosophila melanogaster.