title: In vivo models of P-glycoprotein-mediated multidrug resistance.
authors.affiliation: National Cancer Institute, Laboratory of Cell Biology, Bethesda, MD 20892.
authors.forename: M M
authors.initials: MM
authors.lastname: Gottesman
authors.forename: G H
authors.initials: GH
authors.lastname: Mickisch
authors.forename: I
authors.initials: I
authors.lastname: Pastan
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D000818:Animals; D030801:Animals, Genetically Modified; D000970:Antineoplastic Agents / Q000494:pharmacology; D001693:Biological Transport, Active / Q000187:drug effects; D002999:Clone Cells / Q000187:drug effects; D003001:Cloning, Molecular; D016572:Cyclosporine / Q000494:pharmacology; D018432:Drug Resistance, Multiple; D006801:Humans; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000235:genetics; D011802:Quinidine / Q000494:pharmacology; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D015203:Reproducibility of Results; D012107:Research Design; D012680:Sensitivity and Specificity; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014700:Verapamil / Q000494:pharmacology
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000970:Antineoplastic Agents; D011993:Recombinant Fusion Proteins; D016572:Cyclosporine; D014700:Verapamil; D011802:Quinidine