Transfusion-transmitted hepatitis virus infection.
For many years, viral hepatitis has been considered to be a frequent and serious adverse outcome of blood transfusion. The majority of cases have been due to hepatitis B and C viruses, which, respectively, are DNA and RNA viruses. Both are lipid enveloped and are susceptible to viral inactivation procedures. Careful donor screening and the use tests for HBsAg and anti-HBc have essentially eliminated the risk of transfusion-transmitted HBV infection.
Dodd
R Y
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Transmissible Diseases Department, American Red Cross, Holland Laboratory, Rockville, Maryland, USA.
D001782:Blood Donors; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission; D006518:Hepatitis Viruses / Q000145:classification / Q000276:immunology / Q000302:isolation & purification; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission*; D006801:Humans; D008403:Mass Screening; D015995:Prevalence; D016036:Seroepidemiologic Studies; D065227:Transfusion Reaction; D014481:United States / Q000453:epidemiology; D014766:Viremia / Q000821:virology
D006508:Hepatitis Antibodies