title: Evolutionary conservation of a microsatellite in the Wilms tumour (WT) gene: mapping in sheep and cattle.
abstract: A microsatellite in the WT (Wilms tumour) gene is shown to be evolutionarily conserved in a range of mammals. The microsatellite was monomorphic in pig and two alleles have been found in goat. In cattle, a one-base size polymorphism has been discovered outside the microsatellite. WT was genetically mapped to bovine chromosome 15 and to sheep chromosome 15 by synteny mapping. Conservation of chromosome segments of HSA11 and BTA15 is discussed.
authors.affiliation: Laboratoire de Génétique biochimique et de Cytogénétique, France.
authors.forename: D
authors.initials: D
authors.lastname: Vaiman
authors.forename: E
authors.initials: E
authors.lastname: Pailhoux
authors.forename: E
authors.initials: E
authors.lastname: Payen
authors.forename: N
authors.initials: N
authors.lastname: Saïdi-Mehtar
authors.forename: C
authors.initials: C
authors.lastname: Cotinot
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002874:Chromosome Mapping / Q000662:veterinary; D017124:Conserved Sequence / Q000235:genetics*; D004276:DNA, Satellite / Q000235:genetics*; D016162:Genes, Wilms Tumor / Q000235:genetics*; D008040:Genetic Linkage; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012756:Sheep
chemical_list: D004276:DNA, Satellite