title: Technetium-99m MIBI uptake in recurrent parathyroid carcinoma and brown tumors.
abstract: Demonstrable parathyroid adenoma in delayed (3-hr) 99mTc-MIBI neck imaging and localization of 201Tl-chloride in brown tumors mimicking skeletal metastases have been reported. Technetium-99m-MIBI scintigraphy is currently the imaging modality of choice for localizing parathyroid tumors in patients with recurrent hyperparathyroidism. This report is a good example of the use of 99mTc-MIBI in the diagnostic work-up of a patient with recurrent hyperparathyroidism, which turned out to be due to parathyroid carcinoma rather than the initial histopathologic diagnosis of parathyroid adenoma. Additionally, the patient's total body 99mTc-MIBI and 99mTc-MDP bone images showed multiple focal lesions in the bone-mimicking metastases.
authors.affiliation: Peking Union Medical College, Beijing, China.
authors.forename: G
authors.initials: G
authors.lastname: Lu
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: J Y
authors.initials: JY
authors.lastname: Xiu
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging; D000328:Adult; D001847:Bone Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000556:secondary; D003937:Diagnosis, Differential; D005260:Female; D006101:Granuloma, Giant Cell / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi