title: Pediatric appendectomy.
abstract: OBJECTIVE
  To define patterns of care and outcome for pediatric appendectomy.
  
  
  METHODS
  A study was designed to evaluate all pediatric appendectomies performed in the 147 Department of Defense hospitals worldwide. Cases of nonincidental appendectomy were identified through discharge diagnoses and operative logs, and 98.6% of the charts were retrieved for review. All charts were abstracted, and data were entered into a 127-field database for analysis.
  
  
  RESULTS
  Over a 12-month period, ending January 1993, appendectomy was performed on 1,366 pediatric patients in the Department of Defense hospital system. The patients' median age was 12 years (range, 6 months to 18 years); 59% were male. The diagnosis was normal appendix for 157 patients (12%), acute nonperforated appendicitis for 930 (68%), and perforated appendicitis for 279 (20%). Age < or = 8 years was predictive (P < .001) of a higher rate of perforated appendicitis (33% v 18%) but was not predictive of normal pathology (13% v 11%). Female gender was associated with a significantly higher rate of normal pathology (17% v 8%; P < .001) but not of perforation (18% v 22%). Temperature elevation and right lower quadrant pain and tenderness did not clinically distinguish between diagnostic groups. Sixty-two percent of patients with a normal appendix had a white blood cell count of more than 10,000/mm3, as did 91% of patients with acute or perforated appendicitis. Those with perforated appendicitis received pre- and postoperative antibiotics, primarily ampicillin/gentamicin/clindamycin or Flagyl (41%), cefoxitin (34%), or Unasyn (15%). In 77% of this subgroup, intraoperative cultures were positive, with isolates for Escherichia coli (76%) Enterococcus (30%), Bacteroides (24%), and Pseudomonas (20%) predominating. There were no deaths. Major complications occurred in 1.2% of patients with acute appendicitis and in 6.4% of those with perforated appendicitis; there were no major complications in the group with normal appendectomies. The hospitalization period was more than 7 days for 1.6%, 40%, and 3.8%, respectively.
  
  
  CONCLUSIONS
  This large series, from a large number of hospitals, with multiple practitioners, can serve as a community standard for pediatric appendectomy in the 1990s.
authors.affiliation: Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: R H
authors.initials: RH
authors.lastname: Pearl
authors.forename: D A
authors.initials: DA
authors.lastname: Hale
authors.forename: M
authors.initials: M
authors.lastname: Molloy
authors.forename: D C
authors.initials: DC
authors.lastname: Schutt
authors.forename: D P
authors.initials: DP
authors.lastname: Jaques
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology / Q000628:therapy; D000293:Adolescent; D000367:Age Factors; D000900:Anti-Bacterial Agents; D001062:Appendectomy / Q000379:methods / Q000592:standards*; D001064:Appendicitis / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D002481:Cellulitis / Q000188:drug therapy / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D007416:Intestinal Perforation / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D007430:Intraoperative Care; D010535:Laparoscopy; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D011182:Postoperative Care; D011446:Prospective Studies; D012422:Rupture, Spontaneous; D012737:Sex Factors
chemical_list: D000900:Anti-Bacterial Agents