title: Cryopreserved homografts in aortic and mitral prosthetic endocarditis: expanding the use of biological tissues in complex cardiac infections.
abstract: The case of a 27-year-old male heroin addict suffering from mitral and aortic prosthetic valve endocarditis is presented. Double valve re-replacement was performed using cryopreserved aortic homografts. Aortic root replacement with coronary re-implantation and intra-atrial valve implantation for mitral valve replacement were the techniques used. Despite the fatal outcome of this case, it clearly illustrates the possibilities of expanding the indications for combined complex replacement of heart valves by using fully biological tissue of human origin.
authors.affiliation: Department of Cardiovascular Surgery, Hospital Clinicoy Provincial, University of Barcelona, Spain.
authors.forename: C A
authors.initials: CA
authors.lastname: Mestres
authors.forename: A
authors.initials: A
authors.lastname: Ginel
authors.forename: R
authors.initials: R
authors.lastname: Cartana
authors.forename: J L
authors.initials: JL
authors.lastname: Pomar
mesh_terms: D000328:Adult; D001011:Aorta / Q000601:surgery / Q000637:transplantation*; D001021:Aortic Valve; D001705:Bioprosthesis / Q000009:adverse effects*; D015925:Cryopreservation; D004697:Endocarditis, Bacterial / Q000601:surgery*; D017809:Fatal Outcome; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006556:Heroin Dependence; D006801:Humans; D008297:Male; D008943:Mitral Valve; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012086:Reoperation; D013290:Streptococcal Infections / Q000601:surgery; D013298:Streptococcus sanguis; D015819:Substance Abuse, Intravenous; D014184:Transplantation, Homologous