[Occurrence of bacterial infection and sensitivity of their causative agents to antibiotic drugs in patients with acute leukemias].
The paper summarizes the results of the study of bacterial infections, occurring in neutropenic patients with acute leukaemia treated at the Radivoje Berovic Intensive care unit of the Institute of Haematology, University Clinical Centre, Belgrade. The majority of infectious episodes, as well as most bacteriaemias, were caused by Gram-positive bacteria keeping rapid increase of Gram-positive bacteriaemias in neutropenic patients. Our results suggest that in studied hospital conditions, amikacin should replace gentamicin as empiric antibiotic therapy (in addition to a beta-lactam antibiotic). In non-responding patients addition of an anti-staphylococcal agent should be considered.
Mijović
A
A
Institute of Haematology, University Clinical Centre, Belgrade.
Mijović
A
A
Bosković
D
D
Rolović
Z
Z
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000150:complications / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000150:complications
Ucestalost bakterijskih infekcija i ostljivost njihovih uzrocnika na antibiotske lekove kod bolesnika s akutnom leukemijom.