Structure/function studies of mammalian Na-H exchangers--an update.
Four mammalian Na+/H+ exchangers have recently been cloned. Despite the structural similarity, these Na+/H+ exchanger isoforms differ in kinetic characteristics and their response to external stimuli. The present review deals with the recent developments in their functional characterization and their short-term regulation.
Yun
C H
CH
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Tse
C M
CM
Nath
S
S
Levine
S L
SL
Donowitz
M
M
D000818:Animals; D006801:Humans; D008322:Mammals / Q000378:metabolism*; D017923:Sodium-Hydrogen Exchangers / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship
D017923:Sodium-Hydrogen Exchangers