title: [Use of immunoglobulins G in the treatment of nervous system diseases].
abstract: Short term and long term beneficial effects of IgG administration have been studied in 4 groups of neuro-immunological diseases: Polymyositis, dermatomyositis and myasthenia. Peripheral neuropathies (myelinopathies), primarily in Guillain-Barré syndrome and in chronic inflammatory polyneuropathy. Children intractable Epilepsy. Multiple Sclerosis. Actual results are in favor of an objective and marked improvement (after 1 or 2 months) in the first 2 groups using intravenous IgG. In M.S. patients, the short term treatment of bouts (especially: optic neuritis) seems promising. Results of the only one long term (later than 10 years) trial are in favor of a significant slowing of the progression of M.S. comparatively to the predictive curve of disease.
authors.affiliation: INSERM U134, Hôpital de la Salpêtrière, Paris.
authors.forename: E
authors.initials: E
authors.lastname: Schuller
mesh_terms: D004827:Epilepsy / Q000628:therapy; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D009103:Multiple Sclerosis / Q000628:therapy; D009135:Muscular Diseases / Q000628:therapy; D009422:Nervous System Diseases / Q000628:therapy*; D009468:Neuromuscular Diseases / Q000628:therapy; D010523:Peripheral Nervous System Diseases / Q000628:therapy
chemical_list: D007074:Immunoglobulin G
vernacular_title: L'utilisation des immunoglobulines G dans le traitement des maladies du système nerveux.