Stimulation of sarcolemmal sodium-hydrogen exchange in cardiac myocytes is not responsible for the positive inotropic action of alpha 1 adrenergic agonists.
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INSERM U-390, Physiopathologie Cardiovasculaire, CHU Arnaud de Villeneuve, Montpellier, France.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D009200:Myocardial Contraction / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism*; D012508:Sarcolemma / Q000187:drug effects* / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D017923:Sodium-Hydrogen Exchangers / Q000187:drug effects* / Q000378:metabolism; D013268:Stimulation, Chemical
D000316:Adrenergic alpha-Agonists; D017923:Sodium-Hydrogen Exchangers; D012964:Sodium; D002118:Calcium