The increasing effect of some synthetic peptides on luminol-dependent chemiluminescence of mouse blood.
Some synthetic peptides increased the luminol-dependent chemiluminescence of mouse blood during phagocytosis. It is suggested that the levels of antimicrobial activity of the neutrophil peroxidase system can be raised very quickly (within some dozen of seconds) by these peptides. This raises the possibility of finding a new approach to the therapy for infectious diseases.
Rogovine
V V
VV
Institute of Chemical Physics, Academy of Sciences of Russia, Moscow.
Mushtakova
V M
VM
D000595:Amino Acid Sequence; D000818:Animals; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D009504:Neutrophils / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D010455:Peptides / Q000138:chemical synthesis / Q000494:pharmacology*; D010544:Peroxidases / Q000097:blood*; D010587:Phagocytosis / Q000187:drug effects*; D013268:Stimulation, Chemical
D010455:Peptides; D008165:Luminol; D010544:Peroxidases