title: Visual system abnormalities in adrenomyeloneuropathy.
abstract: We studied the visual system in 59 men with adrenomyeloneuropathy. Pattern-reversal visual evoked potentials, magnetic resonance imaging, and clinical examination revealed that visual pathways are affected in 63% of patients, involving the optic discs, optic nerves, lateral geniculate bodies, optic radiations, and parietooccipital cortex. This indicates both primary demyelination of the optic nerves and discs, and more diffuse involvement of postchiasmal structures.
authors.affiliation: Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA.
authors.forename: P W
authors.initials: PW
authors.lastname: Kaplan
authors.forename: B
authors.initials: B
authors.lastname: Kruse
authors.forename: R J
authors.initials: RJ
authors.lastname: Tusa
authors.forename: J
authors.initials: J
authors.lastname: Shankroff
authors.forename: J
authors.initials: J
authors.lastname: Rignani
authors.forename: H W
authors.initials: HW
authors.lastname: Moser
mesh_terms: D000326:Adrenoleukodystrophy / Q000150:complications*; D000328:Adult; D005074:Evoked Potentials, Visual / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D014786:Vision Disorders / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology