(E)-3-tridecen-2-one, an antibiotic from the interdigital glands of black-tailed deer Odocoileus hemionus columbianus.
(E)-3-tridecen-2-one, the major volatile component of interdigital gland extracts from the black-tailed deer, Odocoileus hemionus columbianus, inhibited the growth of gram-positive bacteria and fungi. The bacteria, Propionibacterium acnes, and the fungi, Trichophyton mentagrophytes had a minimum inhibitory concentration (MIC) of 12.5 micrograms/mL and 25 micrograms/mL, respectively.
Wood
W F
WF
Department of Chemistry, Humboldt State University, Arcata, California 95521, USA.
Shaffer
T B
TB
Kubo
A
A
D000475:Alkenes / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D003670:Deer / Q000378:metabolism*; D005088:Exocrine Glands / Q000378:metabolism*; D005658:Fungi / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
C093289:3-tridecen-2-one; D000475:Alkenes