Binding of amaranthin in photoreceptors of monkey retina.
The binding of amaranthin, specific for the Gal beta 1,3 GalNAc and NeuAc alpha 2,3 Gal beta 1,3 GalNAc sequences, to the photoreceptors of the monkey retina was investigated using the avidin-biotinylated peroxidase method. Amaranthin bound to the surfaces of both cone and rod photoreceptors. This and previous lectin histochemical studies show that O-glycoside-linked glycoconjugates are present on the surfaces of both cones and rods: Gal beta 1,3 GalNAc and NeuAc alpha 2,3 Gal beta 1,3 GalNAc are the terminal sugars of the glycoconjugates around cones and rods, respectively.
Uehara
F
F
Department of Ophthalmology, Kagoshima University Faculty of Medicine, Japan.
Ohba
N
N
Sameshima
M
M
Unoki
K
K
Okubo
A
A
Yanagita
T
T
Sugata
M
M
Iwakiri
N
N
Nakagawa
S
S
D000818:Animals; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D002240:Carbohydrate Sequence; D006001:Glycoconjugates / Q000032:analysis; D006651:Histocytochemistry; D037102:Lectins / Q000378:metabolism*; D008251:Macaca; D008969:Molecular Sequence Data; D010786:Photoreceptor Cells / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D037121:Plant Lectins; D012160:Retina / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*; D054788:Ribosome Inactivating Proteins; D054789:Ribosome Inactivating Proteins, Type 1; D014312:Trisaccharides / Q000032:analysis
D015295:Antigens, Tumor-Associated, Carbohydrate; D006001:Glycoconjugates; D037102:Lectins; D037121:Plant Lectins; D054789:Ribosome Inactivating Proteins, Type 1; C064068:Thomsen-Friedenreich antigen, cryptic; D014312:Trisaccharides; C061152:amaranthin protein, Amaranthus; C016467:Thomsen-Friedenreich antigen; D054788:Ribosome Inactivating Proteins