Time to peak serum antibody response to influenza vaccine.
The time to the appearance of a peak serum antibody response to influenza virus vaccine is not clearly defined. We compared the most commonly used time intervals described in the literature--4 and 6 weeks after vaccination. We studied 118 elderly patients from three different geographic sites. The 1992 to 1993 trivalent inactivated influenza virus vaccine containing influenza virus A/Beijing/353/89 (H3N2), influenza virus A/Texas/36/91 (H1N1), and influenza virus B/Panama/45/90 was used. No statistically significant differences were found at the 4- and 6-week intervals after vaccination.
Rastogi
S
S
Department of Internal Medicine, Hackensack Medical Center, New Jersey 07601.
Gross
P A
PA
Bonelli
J
J
Dran
S
S
Levandowski
R A
RA
Russo
C
C
Weksler
M E
ME
Kaye
D
D
Levison
M
M
Abrutyn
E
E
D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000097:blood; D004194:Disease; D006386:Hemagglutination Tests; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D006389:Hemagglutinins, Viral / Q000276:immunology; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D009981:Influenza B virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D009515:New Jersey; D009519:New York City; D015143:Philadelphia; D013997:Time Factors
D000914:Antibodies, Viral; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D006389:Hemagglutinins, Viral; D007252:Influenza Vaccines