title: Retardation by the soybean Bowman-Birk inhibitor of elastin hydrolysis catalyzed by leukocyte proteinases.
abstract: The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and a mixture of both. The inhibitory effect is practically unaffected by both the adsorption of the enzymes on elastin and prolongation of the enzymatic reaction.
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University, Russian Federation.
authors.forename: T V
authors.initials: TV
authors.lastname: Tikhonova
authors.forename: I P
authors.initials: IP
authors.lastname: Gladysheva
authors.forename: N I
authors.initials: NI
authors.lastname: Larionova
mesh_terms: D000327:Adsorption; D056649:Cathepsin G; D002403:Cathepsins / Q000037:antagonists & inhibitors*; D004549:Elastin / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D019272:Leukocyte Elastase; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors*; D012697:Serine Endopeptidases; D014358:Trypsin Inhibitor, Bowman-Birk Soybean / Q000494:pharmacology*
chemical_list: D014358:Trypsin Inhibitor, Bowman-Birk Soybean; D004549:Elastin; D002403:Cathepsins; D012697:Serine Endopeptidases; C534094:CTSG protein, human; D056649:Cathepsin G; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase