Rapid antibody test for fragile X syndrome.
Fragile X syndrome is the most common known cause of inherited mental retardation. Identification of patients and carriers of fragile X syndrome is usually done with a DNA test system but we have developed a rapid antibody to identify fragile X patients. This non-invasive test requires only 1 or 2 drops of blood and can be used for screening large groups of mentally retarded people and neonates for fragile X syndrome.
Willemsen
R
R
Department of Clinical Genetics, Erasmus University, Rotterdam, Netherlands.
Mohkamsing
S
S
de Vries
B
B
Devys
D
D
van den Ouweland
A
A
Mandel
J L
JL
Galjaard
H
H
Oostra
B
B
D000911:Antibodies, Monoclonal; D004247:DNA / Q000235:genetics; D005260:Female; D051860:Fragile X Messenger Ribonucleoprotein 1; D005600:Fragile X Syndrome / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D006580:Genetic Carrier Screening; D006579:Heterozygote; D006801:Humans; D008297:Male; D009419:Nerve Tissue Proteins / Q000097:blood; D016601:RNA-Binding Proteins / Q000097:blood
D000911:Antibodies, Monoclonal; D004247:DNA; D051860:Fragile X Messenger Ribonucleoprotein 1; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins; C497683:FMR1 protein, human