title: ABT-299, a potent antagonist of platelet activating factor.
authors.affiliation: Abbott Laboratories, Abbott Park, IL 60064, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Summers
authors.forename: D H
authors.initials: DH
authors.lastname: Albert
authors.forename: S K
authors.initials: SK
authors.lastname: Davidsen
authors.forename: R G
authors.initials: RG
authors.lastname: Conway
authors.forename: J H
authors.initials: JH
authors.lastname: Holms
authors.forename: T J
authors.initials: TJ
authors.lastname: Magoc
authors.forename: G
authors.initials: G
authors.lastname: Luo
authors.forename: P
authors.initials: P
authors.lastname: Tapang
authors.forename: D A
authors.initials: DA
authors.lastname: Rhein
authors.forename: G W
authors.initials: GW
authors.lastname: Carter
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D001794:Blood Pressure / Q000187:drug effects; D004487:Edema / Q000517:prevention & control; D004950:Esterases / Q000097:blood; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D007211:Indoles / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D008070:Lipopolysaccharides / Q000633:toxicity; D051379:Mice; D015394:Molecular Structure; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000494:pharmacology; D010980:Platelet Membrane Glycoproteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011355:Prodrugs / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D011726:Pyridinium Compounds / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D012772:Shock, Septic / Q000517:prevention & control; D013844:Thiazoles / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D007211:Indoles; D008070:Lipopolysaccharides; D010972:Platelet Activating Factor; D010980:Platelet Membrane Glycoproteins; D011355:Prodrugs; D011726:Pyridinium Compounds; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D013844:Thiazoles; C039351:platelet activating factor receptor; C093306:ABT 299; D004950:Esterases; C093307:A 85783.0