Acquired laryngeal lesions. Pathologic study using serial macrosections.
OBJECTIVE
To present the pathologic findings of acquired lesions of the larynx in infants.


METHODS
The Laryngeal Development Laboratory of Children's Memorial Hospital, Chicago, Ill.


METHODS
One hundred fifteen larynges received at postmortem examination from 1975 to 1992.


METHODS
Acquired laryngeal lesions from intubation trauma.


METHODS
Whole-organ serial section of larynges.


RESULTS
Fifty-three of the 115 specimens exhibited acquired laryngeal lesions: 36, submucosal mucous gland hyperplasia; 12, submucosal fibrosis; 10, granulation tissue; eight, ulceration; eight, fragmented or distorted cricoid; four, cricoid ossification; four, ductal cysts; three, healed furrows, and one, anterior glottic synechia. Some specimens exhibited more than one type of acquired abnormality.
Chen
J C
JC
Department of Otolaryngology, National Taiwan University Hospital, Taipei.
Holinger
L D
LD
D005260:Female; D005865:Gestational Age; D016591:Histocytological Preparation Techniques; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007442:Intubation, Intratracheal / Q000009:adverse effects; D007818:Laryngeal Diseases / Q000209:etiology / Q000473:pathology*; D007829:Laryngostenosis / Q000209:etiology / Q000473:pathology; D007830:Larynx / Q000473:pathology; D008297:Male