title: Mechanisms of resistance to topoisomerase inhibitors.
authors.affiliation: Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854-5635.
authors.forename: A Y
authors.initials: AY
authors.lastname: Chen
authors.forename: L F
authors.initials: LF
authors.lastname: Liu
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D001426:Bacterial Proteins; D002166:Camptothecin / Q000494:pharmacology; D015195:Drug Design; D004351:Drug Resistance; D004926:Escherichia coli / Q000201:enzymology; D005656:Fungal Proteins; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors*; D009369:Neoplasms / Q000188:drug therapy; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D001426:Bacterial Proteins; D005656:Fungal Proteins; D009363:Neoplasm Proteins; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D002166:Camptothecin