Determination of normal human fetal immunoglobulin M levels.
Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.
Vick
D J
DJ
Department of Obstetrics & Gynecology, University of Virginia Health Sciences Center, Charlottesville.
Hogge
W A
WA
Normansell
D E
DE
Burkett
B J
BJ
Harbert
G M
GM
D017218:Cordocentesis; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D005315:Fetal Diseases / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D005865:Gestational Age; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007231:Infant, Newborn; D007234:Infant, Premature; D007239:Infections / Q000097:blood / Q000175:diagnosis / Q000196:embryology / Q000276:immunology; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012044:Regression Analysis
D007075:Immunoglobulin M