title: [Gatroesophageal reflux in pregnant women].
abstract: Heartburn is a common symptom in pregnancy, affecting about two-thirds of pregnant women. The aetiology of gastro-oesophageal reflux in pregnancy is multifactorial. Reduced lower basal gastro-oesophageal sphincter pressure, increased intragastric pressure, delayed intestinal transit time and duodenogastric reflux have been found in pregnant women with heartburn, all factors which dispose to increased gastro-oesophageal reflux. Gastric emptying is apparently normal during pregnancy, but delayed during delivery. Therapy involves lifestyle modification and nonsystemic medication as the initial choices. H-2-antagonists should only be used in severe and refractory cases.
authors.affiliation: Kirurgisk afdeling D, Amtssygehuset i Glostrup.
authors.forename: M
authors.initials: M
authors.lastname: Okholm
authors.forename: S M
authors.initials: SM
authors.lastname: Jensen
mesh_terms: D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology
vernacular_title: Gastroøsofageal refluks hos gravide.