[Structure-activity relations of isochromanylpenicillins].
Isochroman is substituted and bound to 6-aminopenicillanic acid either directly or by a spacer in 1-position. In addition to the isochromans two homoisochromans are tested. The activities of the new penicillins against grampositive and gramnegative bacteria are compared with those of benzylpenicillin.
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Institut für Pharmazeutische Chemie, Westfälischen Wilhelms-Universität, Münster.
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D001419:Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010400:Penicillin G / Q000737:chemistry / Q000494:pharmacology; D010406:Penicillins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
D010406:Penicillins; D010400:Penicillin G
Struktur-Wirkungs-Beziehungen an Isochromanylpenicillinen.