title: Dynamic high-field MR imaging in experimental porcine acute pancreatitis.
abstract: The effects of acute pancreatitis on MR imaging signal intensities (SIs) were determined in an experimental study at 1.0 T. Oedematous pancreatitis was induced in 9 piglets and haemorrhagic pancreatitis in 11 piglets. Each animal served as its own control for MR imaging before and after induction of pancreatitis. T1-weighted spin echo (450/15 ms) and dynamic turbo FLASH (flip angle 8 degrees) sequences were used without contrast medium in testing the stability of the SI measurements. There was no significant difference in the SI-versus-time curves of the pancreas in piglets with oedematous and haemorrhagic pancreatitis. However, the difference in mean SIs between healthy and diseased piglets was significant. Thus, although non-contrast MR may be useful in the diagnosis of acute pancreatitis, it does not distinguish between oedematous and haemorrhagic pancreatitis.
authors.affiliation: Department of Radiology, Helsinki University Central Hospital, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Piironen
authors.forename: R
authors.initials: R
authors.lastname: Kivisaari
authors.forename: P
authors.initials: P
authors.lastname: Pitkäranta
authors.forename: V P
authors.initials: VP
authors.lastname: Poutanen
authors.forename: P
authors.initials: P
authors.lastname: Laippala
authors.forename: P
authors.initials: P
authors.lastname: Laurila
authors.forename: L
authors.initials: L
authors.lastname: Kivisaari
mesh_terms: D000208:Acute Disease; D000818:Animals; D004487:Edema / Q000175:diagnosis / Q000209:etiology; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000175:diagnosis* / Q000209:etiology; D013552:Swine