[Clinical significance of increased serum soluble interleukin-2 receptor levels in patients with pulmonary tuberculosis].
The serum soluble interleukin-2 receptor (sIL-2R) was measured in 40 patients with pulmonary tuberculosis by using sandwich enzyme linked immunosorbent assay. The results show that the levels of sIL-2R in sera of the various stage patients are markedly higher than that of the normal controls and the serum levels of sIL-2R were associated significantly with the patients' conditions. These findings suggest that sIL-2R may be an useful referential indicator for diagnosing, monitoring and predicting pulmonary tuberculosis.
Chui
J J
JJ
Department of Infectious Diseases, First Affiliated Hospital of Hubei Medical University, Wuhan.
Fan
P
P
Li
J
J
D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000378:metabolism*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000276:immunology*
D000995:Antitubercular Agents; D015415:Biomarkers; D015375:Receptors, Interleukin-2