title: Biotypes of oral Candida albicans isolates in human immunodeficiency virus-infected patients from diverse geographic locations.
abstract: Oral Candida albicans isolates from HIV-infected individuals in Hong Kong, Australia, Germany and England were characterised using a biotyping system based on enzyme profiles, carbohydrate assimilation patterns and boric acid resistance of the yeasts. A total of 44 biotypes were found amongst the 117 oral C. albicans isolates examined. The major biotype A1R accounted for 17.9% of all isolates while the second commonest biotype was A1S (11.1% of isolates). Whereas these two biotypes were isolated from all the regions studied, there were a number of other biotypes unique to individual countries. The data indicate that there are many different sub-strains of oral C. albicans in HIV-infected patients, some of which are globally prevalent. However, further work is required to ascertain the diversity of oral C. albicans biotypes, if any, in health and disease.
authors.affiliation: Oral Biology Unit, University of Kong.
authors.forename: P C
authors.initials: PC
authors.lastname: Tsang
authors.forename: L P
authors.initials: LP
authors.lastname: Samaranayake
authors.forename: H P
authors.initials: HP
authors.lastname: Philipsen
authors.forename: M
authors.initials: M
authors.lastname: McCulloug
authors.forename: P A
authors.initials: PA
authors.lastname: Reichart
authors.forename: A
authors.initials: A
authors.lastname: Schmidt-Westhausen
authors.forename: C
authors.initials: C
authors.lastname: Scully
authors.forename: S R
authors.initials: SR
authors.lastname: Porter
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D001315:Australia / Q000453:epidemiology; D002176:Candida albicans / Q000145:classification*; D002180:Candidiasis, Oral / Q000453:epidemiology / Q000382:microbiology*; D004739:England / Q000453:epidemiology; D005858:Germany / Q000453:epidemiology; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D016533:Mycological Typing Techniques