title: Antibacterial activities of cefprozil compared with those of 13 oral cephems and 3 macrolides.
abstract: Thirteen oral cephems (cefprozil, loracarbef, cefaclor, cefuroxime axetil, cefpodoxime proxetil, cefetamet pivoxil, cefixime, cefdinir, cefadroxil, cephradine, cephalexin, cefatrizine, and cefroxadine), the cephalosporin class representative cephalothin, cefazolin, and the macrolides erythromycin, clarithromycin, and azithromycin were compared for their antibacterial activities against 790 recent clinical isolates. These oral agents differed in their spectra and antibacterial potencies against community-acquired pathogens.
authors.affiliation: Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Fung-Tomc
authors.forename: E
authors.initials: E
authors.lastname: Huczko
authors.forename: T
authors.initials: T
authors.lastname: Stickle
authors.forename: B
authors.initials: B
authors.lastname: Minassian
authors.forename: B
authors.initials: B
authors.lastname: Kolek
authors.forename: K
authors.initials: K
authors.lastname: Denbleyker
authors.forename: D
authors.initials: D
authors.lastname: Bonner
authors.forename: R
authors.initials: R
authors.lastname: Kessler
mesh_terms: D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000494:pharmacology*; D018942:Macrolides; D008826:Microbial Sensitivity Tests; D000097670:Cefprozil
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D018942:Macrolides; D000097670:Cefprozil