[Use of an GnRH analogue for induction of gonadotrophin ovulatory surge in cycles stimulated with clomiphene citrate and menopausal gonadotropin in an in vitro fertilization program].
In 23 women treated for sterility by the in vitro fertilization method the gonadotropins ovulatory surge was stimulated by applying a GnRH analogue (Buserelin). The authors showed that a single injection of GnRH analogue in the cycles stimulated with clomiphene citrate and menopausal gonadotropin causes pituitary output of both LH and FSH which is sufficient for morphological and functional maturity of the oocytes. After such treatment two patients conceived and delivered healthy babies.
Wołczyński
S
S
Zakładu Endokrynologii Ginekologicznej, Instytutu Połoznictwa i Chorób Kobiecych, Białymstoku.
Kulikowski
M
M
Syrewicz
M
M
Kuczyński
W
W
Grochowski
D
D
Sola
E
E
Szamatowicz
M
M
D000328:Adult; D002064:Buserelin / Q000494:pharmacology / Q000627:therapeutic use*; D002996:Clomiphene / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008596:Menotropins / Q000494:pharmacology / Q000627:therapeutic use; D008597:Menstrual Cycle / Q000187:drug effects; D010060:Ovulation / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome
D002996:Clomiphene; D008596:Menotropins; D002064:Buserelin
Zastosowanie analogu GnRH do wywołania szczytu owulacyjnego gonadotropin w cyklach stymulowanych cytrynianem klomifenu i gonadotropina menopauzalna w programie pozaustrojowego zapłodnienia.