title: Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17.
abstract: The murine homolog of the human anaplastic lymphoma kinase gene, which encodes a membrane-spanning receptor tyrosine kinase in the insulin receptor kinase subfamily, was assigned to mouse Chromosome 17 by interspecific backcross analysis. This assignment further confirms the homology between a portion of the distal Chromosome 17 and the short arm of human chromosome 2 and extends this region in the mouse by an additional 3 cM.
authors.affiliation: Department of Experimental Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101-0318, USA.
authors.forename: P
authors.initials: P
authors.lastname: Mathew
authors.forename: S W
authors.initials: SW
authors.lastname: Morris
authors.forename: J R
authors.initials: JR
authors.lastname: Kane
authors.forename: S A
authors.initials: SA
authors.lastname: Shurtleff
authors.forename: M
authors.initials: M
authors.lastname: Pasquini
authors.forename: N A
authors.initials: NA
authors.lastname: Jenkins
authors.forename: D J
authors.initials: DJ
authors.lastname: Gilbert
authors.forename: N G
authors.initials: NG
authors.lastname: Copeland
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000818:Animals; D002874:Chromosome Mapping / Q000662:veterinary; D005260:Female; D008297:Male; D051379:Mice / Q000235:genetics*; D008810:Mice, Inbred C57BL; D009115:Muridae; D012150:Polymorphism, Restriction Fragment Length; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D020794:Receptor Protein-Tyrosine Kinases
chemical_list: C000626173:ALK protein, human; C000626174:Alk protein, mouse; D000077548:Anaplastic Lymphoma Kinase; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases