Resolution of cryptococcal meningitis and associated granuloma lung with antifungal therapy: report of a case.
A 49-year-old diabetic male had been unsuccessfully treated with antitubercular therapy for a granulomatous lesion of the left lung detected elsewhere nine months ago. He presented with evidence of meningitis which was found to be due to infection with Cryptococcus neoformans. Both the meningeal and lung lesions resolved after 6 weeks of combined therapy with amphotericin B and flucytosine. The report of the case along with a brief review of the relevant literature is presented.
Ray
D
D
Department of Chest Diseases, Christian Medical College, Vellore.
Gnanamuthu
C
C
D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D003453:Cryptococcosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005437:Flucytosine / Q000008:administration & dosage / Q000627:therapeutic use; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged
D000666:Amphotericin B; D005437:Flucytosine