title: Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells.
abstract: In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude mice. The tumours formed by the annexin VI+ A431 cells were morphologically and histologically similar to those formed by the wild-type cells.
authors.affiliation: Department of Physiology, University College London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Theobald
authors.forename: A
authors.initials: A
authors.lastname: Hanby
authors.forename: K
authors.initials: K
authors.lastname: Patel
authors.forename: S E
authors.initials: SE
authors.lastname: Moss
mesh_terms: D000818:Animals; D017317:Annexin A6 / Q000032:analysis / Q000096:biosynthesis*; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D002460:Cell Line; D002999:Clone Cells; D006801:Humans; D007150:Immunohistochemistry; D051379:Mice; D008819:Mice, Nude; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured
chemical_list: D017317:Annexin A6