[Behavior of some parameters of the autonomic nervous system in patients with bronchial asthma].
It is well known that beta receptors play a crucial role in maintaining tonus of smooth muscles of the airways. In this study the authors have indirectly assessed the beta receptor performance by measuring serum cAMP levels before and after intravenous administration of Salbutamol. Parallelly the activity of the parasympathetic system was analysed. The observed increases of serum cAMP dependent on different duration of the disease. The age of the patients did not affect the observations. These results may imply that disturbances of beta-2 receptors function are acquired in patients with bronchial asthma.
Gawlik
R
R
Katedry i Kliniki Chorób Wewnetrznych i Alergologii, Sl. AM w Zabrzu.
Sachs
K
K
D000328:Adult; D000420:Albuterol / Q000494:pharmacology; D001249:Asthma / Q000503:physiopathology*; D001341:Autonomic Nervous System / Q000502:physiology; D000242:Cyclic AMP / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018343:Receptors, Adrenergic, beta-2 / Q000187:drug effects / Q000502:physiology*
D018343:Receptors, Adrenergic, beta-2; D000242:Cyclic AMP; D000420:Albuterol
Zachowanie sie niektórych parametrów układu autonomicznego u chorych na astme oskrzelowa.