Plasma somatostatin levels in ulcerative colitis.
The circadian (24 hour) rhythmicity of somatostatin in healthy subjects and patients with ulcerative colitis (UC) was studied and established. UC patients were found to have a higher 24-hour amplitude, a higher average level and a longer peak level phase of plasma somatostatin. This finding may indicate a defensive role of somatostatin in inflammatory bowel disease.
Payer
J
J
1st Department of Internal Medicine, Comenius University, Bratislava, Slovak Republic.
Huorka
M
M
Duris
I
I
Mikulecky
M
M
Kratochvílová
H
H
Ondrejka
P
P
Lukác
L
L
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002940:Circadian Rhythm; D003093:Colitis, Ulcerative / Q000097:blood* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013004:Somatostatin / Q000097:blood*
D013004:Somatostatin