cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B.
The sequence of a cDNA encoding a putative chicken RNA-binding protein is reported. The C-terminal portion of the predicted protein is similar to a family of nucleic acid binding proteins that includes murine CArG box-binding factor CBF-A, human hnRNP A/B, hepatitis B enhancer-binding protein E2BP, and AU-rich RNA-binding protein AUF1. These proteins all have two consecutive RNA recognition motifs. However, the N-terminal 72 amino acids of this deduced chicken protein show no relation to the N-terminal sequences of the other proteins. We call this protein chicken ribonucleoprotein, CRP1.
Cvekl
A
A
Laboratory of Molecular and Developmental Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892-2730, USA.
McDermott
J B
JB
Piatigorsky
J
J
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D022762:CCAAT-Enhancer-Binding Proteins; D002645:Chickens; D018076:DNA, Complementary / Q000737:chemistry*; D004268:DNA-Binding Proteins / Q000235:genetics*; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D008969:Molecular Sequence Data; D012261:Ribonucleoproteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics*
D022762:CCAAT-Enhancer-Binding Proteins; D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012261:Ribonucleoproteins; D014157:Transcription Factors