Late effects of radiation on the eye and ocular adnexa.
A clinically useful classification system is suggested that can be used in prospective trials to evaluate the effects of radiation on the visual system. We review radiation-induced pathophysiological and clinical changes of the various ocular structures as well as dose-response data and management of ocular complications. The rationale for the classification scheme chosen is also discussed.
Gordon
K B
KB
Department of Ophthalmology, SUNY Health Science Center Syracuse, USA.
Char
D H
DH
Sagerman
R H
RH
D002386:Cataract / Q000209:etiology / Q000628:therapy; D005123:Eye / Q000528:radiation effects*; D006801:Humans; D015601:Injury Severity Score; D009900:Optic Nerve / Q000528:radiation effects; D009915:Orbit / Q000528:radiation effects; D011832:Radiation Injuries / Q000145:classification* / Q000503:physiopathology / Q000628:therapy; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D012160:Retina / Q000528:radiation effects; D012720:Severity of Illness Index; D014792:Visual Acuity