title: Topographic distributions of monoamine oxidase-B-containing neurons in the mouse striatum.
abstract: We have recently documented the presence of cholinergic neurons containing monoamine oxidase (MAO)-B activity in the striatum of C57BL/6 mouse. In the present study, we have mapped the topographical distributions of MAO-containing neurons in the mouse striatum. Positive neurons were located in the striatum of the entire rostralcaudal extent. However, the distribution of MAO-containing neurons was not uniform in the striatum. The larger number of positive neurons were located in the dorsal region of the C57BL/6 mouse striatum, in contrast to the uniform distributions of choline acetyltransferase-immunoreactive neurons in the mouse striatum. The present results suggest that cholinergic neurons are functionally heterogenous in the mouse striatum.
authors.affiliation: Department of Neurology, Faculty of Medicine, Kyoto University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: I
authors.initials: I
authors.lastname: Akiguchi
authors.forename: J
authors.initials: J
authors.lastname: Kimura
mesh_terms: D000818:Animals; D001931:Brain Mapping; D003342:Corpus Striatum / Q000166:cytology* / Q000201:enzymology; D007150:Immunohistochemistry; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008995:Monoamine Oxidase / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology; D011699:Putamen / Q000166:cytology / Q000201:enzymology
chemical_list: D008995:Monoamine Oxidase