title: Large-scale genotoxicity assessments in the marine environment.
abstract: There are a number of techniques for detecting genotoxicity in the marine environment, and many are applicable to large-scale field assessments. Certain tests can be used to evaluate responses in target organisms in situ while others utilize surrogate organisms exposed to field samples in short-term laboratory bioassays. Genotoxicity endpoints appear distinct from traditional toxicity endpoints, but some have chemical or ecotoxicologic correlates. One versatile end point, the frequency of anaphase aberrations, has been used in several large marine assessments to evaluate genotoxicity in the New York Bight, in sediment from San Francisco Bay, and following the Exxon Valdez oil spill.
authors.affiliation: Department of Biology, Occidental College, Los Angeles, CA, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Hose
mesh_terms: D000413:Alaska; D000818:Animals; D049872:Bivalvia / Q000235:genetics; D004249:DNA Damage; D004784:Environmental Monitoring; D005399:Fishes / Q000235:genetics*; D009152:Mutagenicity Tests; D009153:Mutagens / Q000009:adverse effects / Q000032:analysis*; D009518:New York; D011083:Polycyclic Compounds / Q000009:adverse effects / Q000032:analysis; D012495:San Francisco; D012617:Sea Urchins / Q000235:genetics; D014874:Water Pollutants, Chemical / Q000009:adverse effects / Q000032:analysis*
chemical_list: D009153:Mutagens; D011083:Polycyclic Compounds; D014874:Water Pollutants, Chemical