title: Absorption of (-)-epigallocatechin gallate into rat portal vein.
abstract: Following oral administration of (-)-epigallocatechin gallate to rats, the presence of (-)-epigallocatechin gallate was examined in the portal blood. A compound present in the blood was identified as (-)-epigallocatechin gallate by HPLC and mass spectrometry analysis. The results clearly demonstrate that (-)-epigallocatechin gallate is absorbed, at least in part, into rat portal blood.
authors.affiliation: Food Research Laboratories, Mitsui Norin Co., Ltd., Fujieda-shi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Okushio
authors.forename: N
authors.initials: N
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: F
authors.initials: F
authors.lastname: Nanjo
authors.forename: Y
authors.initials: Y
authors.lastname: Hara
mesh_terms: D000042:Absorption; D000284:Administration, Oral; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D002392:Catechin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D008297:Male; D011169:Portal Vein / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D002392:Catechin; C045651:epigallocatechin gallate