Association of the acral type of pustular psoriasis, Sjögren's syndrome, systemic lupus erythematosus, and Hashimoto's thyroiditis.
We describe a case of a 53-year-old Japanese female suffering from Sjögren's syndrome, systemic lupus erythematosus, and Hashimoto's thyroiditis who developed pustules, erythema, and erosions on her fingers and toes. The histological specimen showed psoriatic changes. Indirect immunofluorescent study using anti-human IL (interleukin)-8 antibody produced positive staining patterns in the lesional epidermis. These findings suggested the diagnosis of acral pustular psoriasis. Diaminodiphenylsulfone at 75 mg orally daily for 20 days and the application of 0.12% betamethasone valerate ointment led to gradual improvement.
Kobayashi
T
T
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
Naka
W
W
Harada
T
T
Nishikawa
T
T
D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D011565:Psoriasis / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications*; D013967:Thyroiditis, Autoimmune / Q000150:complications*