title: Frequency of augmentation mammoplasty in patients with systemic sclerosis: data from the Johns Hopkins-University of Maryland Scleroderma Center.
abstract: The objective was to determine the frequency of augmentation mammoplasty in female patients with systemic sclerosis (SSc). Female patients with a clinical diagnosis of SSc were identified from the registry of the Johns Hopkins-University of Maryland Scleroderma Center, Washington D.C. Chapter of the Scleroderma Foundation, and files of practicing rheumatologists in the Baltimore-Washington metropolitan area. A pretested questionnaire was mailed to all eligible cases. Of 339 cases, 210 (62%) returned completed questionnaires. Three cases reported augmentation mammoplasty with silicone gel-filled prosthesis: 2 (1%) prior to and 1 (0.5%) after physician-diagnosis of SSc. The frequency of augmentation mammoplasty prior to physician-diagnosis of SSc of 9.5 per 1000 does not appear to differ from the expected frequency of 3.3-8.2 per 1000 derived from national population samples. A well-designed case-control study with population-based controls and adequate statistical power is being conducted to examine this possible association.
authors.affiliation: Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore 21201, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Hochberg
authors.forename: R
authors.initials: R
authors.lastname: Miller
authors.forename: F M
authors.initials: FM
authors.lastname: Wigley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects / Q000706:statistics & numerical data*; D008875:Middle Aged; D015995:Prevalence; D012595:Scleroderma, Systemic / Q000453:epidemiology* / Q000209:etiology; D012828:Silicones / Q000009:adverse effects
chemical_list: D012828:Silicones