title: Serological evidence of past hepatitis B infection in liver donor and hepatitis B infection in liver allograft.
abstract: The presence of hepatitis B surface and core antibodies (anti-HBs and anti-HBc) in a liver donor without hepatitis B surface antigen is taken to indicate resolution of hepatitis B and is not considered to contraindicate donation. We report a liver transplant recipient who developed hepatitis B after such a donation. It seems that hepatitis B virus can reside in the liver of a patient who has seemingly recovered from his disease. We recommend avoidance of liver transplants from donors who are positive for anti-HBs and anti-HBc.
authors.affiliation: Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Lowell
authors.forename: T K
authors.initials: TK
authors.lastname: Howard
authors.forename: H M
authors.initials: HM
authors.lastname: White
authors.forename: S
authors.initials: S
authors.lastname: Shenoy
authors.forename: P C
authors.initials: PC
authors.lastname: Huettner
authors.forename: D C
authors.initials: DC
authors.lastname: Brennan
authors.forename: M G
authors.initials: MG
authors.lastname: Peters
mesh_terms: D005260:Female; D006084:Graft Rejection; D006509:Hepatitis B / Q000175:diagnosis*; D006510:Hepatitis B Antibodies / Q000097:blood*; D006511:Hepatitis B Antigens / Q000097:blood* / Q000276:immunology; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D008099:Liver / Q000821:virology*; D008875:Middle Aged; D012698:Serologic Tests; D014019:Tissue Donors
chemical_list: D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens