Assignment to chromosome 11 of mouse p68 RNA helicase gene (Hlr1) and pseudogene (Hlr1-ps1).
The gene encoding murine p68 RNA helicase (Hlr1) was mapped to the distal portion of mouse chromosome 11 by linkage analysis of DNA restriction length polymorphisms using an interspecific genetic backcross between (C57BL/6J x SPRET/Ei) F1 hybrids and SPRET/Ei mice. A closely related gene (Hlr1-ps1) was identified, isolated, and mapped to the proximal part of the same chromosome. Sequence analysis and PCR results suggest that Hlr1-ps1 is a pseudogene, flanked by DNA stretches similar to mouse insertion element IE118.
Petry
P
P
Institut für Genetik, Heinrich-Heine-Universität, Düsseldorf, Germany.
Johnson
K R
KR
Lemaire
L
L
Heinlein
U A
UA
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004247:DNA / Q000737:chemistry; D015246:Deoxyribonuclease EcoRI; D008040:Genetic Linkage; D051379:Mice; D008810:Mice, Inbred C57BL; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D020365:RNA Helicases; D012316:RNA Nucleotidyltransferases / Q000235:genetics*; D017422:Sequence Analysis, DNA
D004247:DNA; D012316:RNA Nucleotidyltransferases; D015246:Deoxyribonuclease EcoRI; D020365:RNA Helicases