title: A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene.
abstract: An alternative splice acceptor site in intron 1 of the human GHF-1/PIT-1 gene was sequenced. The use of this splice site is responsible for a 78-bp in-frame insertion upstream from exon 2 and leads to the hGHF-2/PIT-2 cDNA detected in normal human pituitary.
authors.affiliation: Pharmacology Department, Medical School, Free University of Brussels (V.U.B.), Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Delhase
authors.forename: V
authors.initials: V
authors.lastname: Vila
authors.forename: E L
authors.initials: EL
authors.lastname: Hooghe-Peters
authors.forename: J L
authors.initials: JL
authors.lastname: Castrillo
mesh_terms: D017398:Alternative Splicing / Q000235:genetics*; D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary; D004268:DNA-Binding Proteins / Q000235:genetics*; D006801:Humans; D007438:Introns / Q000235:genetics; D008969:Molecular Sequence Data; D010902:Pituitary Gland / Q000378:metabolism; D050817:Transcription Factor Pit-1; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; C494187:POU1F1 protein, human; D050817:Transcription Factor Pit-1; D014157:Transcription Factors