The effect of different prostaglandins on rat gastric mucosa. Scanning electronmicroscopic investigations.
According to the present investigations prostaglandins showed a specific morphologic effect on (rat) gastric mucosa. Namely: During their effect the foveolae of the mucosa have opened; - which is a convincing sign of mucus production. This phenomenon (i.e. the foveola-opening), showed a direct correlation with the cytoprotective (anti-ulcerogenic) effect of the investigated prostaglandins in the order of PG-I2 > PG-E1 > PG-F2 alpha > 6-keto-PG-F1 alpha.
Balint
G A
GA
Department of Neurology and Psychiatry, Albert Szent-Györgyi Medical University, Szeged, Hungary.
Hulesch
H
H
D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects* / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D011453:Prostaglandins / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D011453:Prostaglandins