Activity of praziquantel (0.5 mg kg-1) against Anoplocephala perfoliata (Cestoda) in equids.
Praziquantel injectable formulation was administered at 0.5 mg k-1 per os to 24 equids naturally infected with 1-183 (average 40) Anoplocephala perfoliata. Drug activity was evaluated by a modified critical test method with necropsy 24 h after treatment. There was variable efficacy of 0-100% (aggregate average 85%); for 18 equids, 93-100%, for three equids, 70-85%, and for three equids, 0-20%.
Lyons
E T
ET
Department of Veterinary Science, University of Kentucky, Lexington 40546-0099, USA.
Tolliver
S C
SC
Stamper
S
S
Drudge
J H
JH
Granstrom
D E
DE
Collins
S S
SS
D000284:Administration, Oral; D000818:Animals; D002589:Cestoda / Q000302:isolation & purification; D002590:Cestode Infections / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases; D006736:Horses; D007413:Intestinal Mucosa / Q000469:parasitology / Q000473:pathology; D008297:Male; D009919:Orchiectomy; D011223:Praziquantel / Q000008:administration & dosage / Q000627:therapeutic use*
D011223:Praziquantel