[Breast-feeding by mothers with positive serum hepatitis B virus test].
Sixty one samples of colostrum from mothers with positive serum Hepatitis B virus (HBV) test were collected and determined for serial HBV markers along with HBV DNA. Results showed that HBsAg, HBeAg and anti-HBc were most likely transferred by milk, while anti-HBs and anti-HBe had less possibility to enter the colostrum (P < 0.01). The overall HBV DNA positive rate was 42.6% in the 61 samples. The various HBV markers detected in mothers' serum presented a high consistency with those discovered in the corresponding milk samples. There were significantly higher rate of milk HBV transmission from mothers with serum positive HBsAg, HBeAg and anti-HBc or either one of them than those with positive for anti-HBs and/or anti-HBe.
Yang
X
X
Hangzhou Maternal and Children Care Hospital.
Cui
M X
MX
Liu
B G
BG
D001942:Breast Feeding; D002353:Carrier State / Q000635:transmission*; D003126:Colostrum / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006509:Hepatitis B / Q000635:transmission*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006513:Hepatitis B e Antigens / Q000032:analysis; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy
D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens