title: [The relationship between serum dehydroepiandrosterone sulfate levels and factors associated with cardiovascular diseases: a cross-sectional study in Japan].
abstract: To explore the relationship between serum DHEAS levels and blood pressure, obesity, smoking habits and drinking habits associated with onset of cardiovascular disease, we examined serum DHEAS levels in 90 males and 183 females, aged 35 to 62 years, who participated in a mass health examination conducted in a town of Aichi prefecture in 1992. The results were as follows. 1. Serum DHEAS levels were significantly higher in males than in females and decreased with age both sexes. 2. Age-adjusted serum DHEAS levels for both sexes decreased with blood pressure and BMI. 3. There were no apparent significance between age-adjusted serum DHEAS levels and smoking habits, whereas age-adjusted serum DHEAS levels were higher in groups of intake of ethanol volume 1-29 g/day than in the groups of intake of more than and less than ethanol volume 1-29 g/day. 4. Age-adjusted serum DHEAS levels were significantly decreased with the rise of sum of factors chosen as risk factor of cardiovascular disease disease in this study. It was suggested that serum DHEAS levels might be useful as an index of accumulation of risk factors of cardiovascular disease. Further studies should be performed to establish the possibilities as an index of genesis and prevention of cardiovascular disease.
authors.affiliation: Department of Public Health, Aichi Medical University.
authors.forename: K
authors.initials: K
authors.lastname: Okamoto
authors.forename: K
authors.initials: K
authors.lastname: Yagyu
authors.forename: R
authors.initials: R
authors.lastname: Sasaki
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000097:blood* / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003687:Dehydroepiandrosterone / Q000097:blood*; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D003687:Dehydroepiandrosterone