title: Infantile spasms combined with partial seizures: electroclinical study of eleven cases.
abstract: We studied 11 infants (7 males) with combined infantile spasms (IS) and partial seizures. The age of onset of the spasms ranged from 6 days to 9 months. All of the children had neurological or CT/MRI abnormalities, and five also had a family history of epilepsy. The clinical and polygraphic patterns of the clusters of spasms combined with partial seizures were analysed. Ten infants were followed-up for a mean period of 3 years, 4 months (range 1 year 10 months to 4 years 11 months). At the last check-up, the seizures were controlled in 2 patients; the others continued to have spasms and/or partial seizures. All of the patients developed mild to severe psychomotor retardation. This condition defines a subgroup of infants presenting with IS, which is distinct from West syndrome.
authors.affiliation: Centro di epilettologia, Ospedale Regina Elena, Milano, Italia.
authors.forename: F
authors.initials: F
authors.lastname: Viani
authors.forename: A
authors.initials: A
authors.lastname: Romeo
authors.forename: M
authors.initials: M
authors.lastname: Mastrangelo
authors.forename: M
authors.initials: M
authors.lastname: Viri
mesh_terms: D004569:Electroencephalography; D004576:Electromyography; D004828:Epilepsies, Partial / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D013036:Spasms, Infantile / Q000150:complications / Q000503:physiopathology*; D016896:Treatment Outcome