title: Epidemic cholera during refugee resettlement in Malawi.
abstract: BACKGROUND
  In June 1988 a cholera epidemic occurred in a Mozambican refugee population resettling in southern Malawi.
  
  
  METHODS
  A case-control study was conducted to determine possible risk factors for disease. The characteristics of 48 refugee households with any member(s) hospitalized for suspected cholera were compared to 441 randomly sampled refugee households without hospitalizations.
  
  
  RESULTS
  Vibrio cholerae 01 was isolated from 50% (5/10) of case-patient stool cultures. Having any water containers with > or = 10 T capacity was associated with a significantly lower odds of suspected cholera in households (adjusted odds ratio [aOR] = 0.02, 95% confidence interval [CI] : 0.003-0.12), as was having metal cooking pots (aOR = 0.3, 95% CI : 0.12-0.7), after adjusting for length of residence and socioeconomic status (logistic regression model). Households with two or more children < 5 years old were at markedly increased odds of suspected cholera (P < 0.0001). These results suggest that water containers and cooking pots served important preventive functions during this cholera outbreak. Young children may have contributed to cholera transmission, but the reason(s) remains undetermined.
authors.affiliation: International Health Program Office, Centers for Disease Control, CDC/EPO/DFE/International Branch, Atlanta, GA 30333, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Hatch
authors.forename: R J
authors.initials: RJ
authors.lastname: Waldman
authors.forename: G W
authors.initials: GW
authors.lastname: Lungu
authors.forename: C
authors.initials: C
authors.lastname: Piri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002771:Cholera / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D008295:Malawi / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011897:Random Allocation; D012036:Refugees / Q000706:statistics & numerical data*; D012307:Risk Factors; D012959:Socioeconomic Factors