Malignancy in Maffucci's syndrome.
Maffucci's syndrome is characterized by multiple enchondromas and subcutaneous hemangiomas. These tumors typically present in early childhood and may lead to significant skeletal deformities. Malignant transformations are a common feature of this syndrome and have been reported in approximately 30% of reported cases, with chondrosarcomas being the most common.
Albregts
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AE
Department of Dermatology, University of Texas-Houston Medical School, USA.
Rapini
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RP
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology; D002648:Child; D002813:Chondrosarcoma / Q000473:pathology; D004687:Enchondromatosis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D005500:Follow-Up Studies; D006391:Hemangioma / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology