Sequence of the dog immunoglobulin alpha and epsilon constant region genes.
The immunoglobulin alpha (IGHAC) and epsilon (IGHEC) germline constant region genes were isolated from a dog liver genomic DNA library. Sequence analysis indicates that the dog IGHEC gene is encoded by four exons spread out over 1.7 kilobases (kb). The IGHAC sequence encompasses 1.5 kb and includes all three constant region coding exons. The complete exon/intron sequence of these genes is described.
Patel
M
M
Department of Cellular and Molecular Biology, Merck Research Laboratories, Rahway, NJ 07065, USA.
Selinger
D
D
Mark
G E
GE
Hickey
G J
GJ
Hollis
G F
GF
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004285:Dogs / Q000276:immunology*; D005803:Genes, Immunoglobulin; D006801:Humans; D007070:Immunoglobulin A / Q000235:genetics*; D007127:Immunoglobulin Constant Regions / Q000235:genetics*; D007073:Immunoglobulin E / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data
D007070:Immunoglobulin A; D007127:Immunoglobulin Constant Regions; D007073:Immunoglobulin E