Amyloidosis secondary to rheumatoid arthritis associated with plexiform change in bilateral temporal lobes.
A 70-year-old woman with rheumatoid arthritis (RA) and secondary amyloidosis presented repeated consciousness loss. The pathological findings at autopsy revealed multi-organic deposits of amyloid A-protein and so-called 'plexiform change' of blood vessels in bilateral temporal lobes. The arterial plexiform change, which is found in the lung specimen of primary pulmonary hypertension, might be a new pathological cerebrovascular change associated with RA.
Matsuki
Y
Y
National Defense Medical College, Tokorozawa.
Suzuki
K
K
Tanaka
N
N
Hirose
T
T
Hosoai
K
K
Kawakami
M
M
Ishizuka
T
T
Kawaguchi
Y
Y
Hidaka
T
T
Nakamura
H
H
D000368:Aged; D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology*; D002544:Cerebral Infarction / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D013702:Temporal Lobe / Q000098:blood supply*