Schweigger-Seidel sheath or ellipsoid in the spleen of guinea hen.
Splenic Schweigger-Seidel sheath or ellipsoid was studied by anti-vimentin monoclonal antibodies, clones 3B4 and V9. The 3B4 mAb recognizes a cell type with cytoplasmic granules and long processes which make a network around the endothelial cells of the penicilliform capillaries. The V9 mAb identifies the reticular cells of the spleen which form the supporting system of the Schweigger-Seidel sheath. The sheath covers the entire length of the penicilliform capillary from the central artery, including the branching area. The appearance of the Schweigger-Seidel sheath in a section depends on the section plane; namely, at the branching area its shape is highly irregular, while close to the red pulp it looks like a sleeve. Therefore, the English term "ellipsoid" does not cover the morphological appearance of this unique splenic structure; the Schweigger-Seidel sheath is a correct term.
Oláh
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I
Second Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.
Kupper
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A
Dúcz
P
P
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D005260:Female; D011200:Poultry; D013154:Spleen / Q000033:anatomy & histology* / Q000378:metabolism; D014746:Vimentin / Q000276:immunology / Q000378:metabolism
D000911:Antibodies, Monoclonal; D014746:Vimentin