title: Carcinoma of the vocal cord. Results after subperichondral cordectomy.
abstract: The clinical outcome of 110 patients operated upon by subperichondral cordectomy between 1982 and 1992 for T1s/T1a, NO, MO carcinomas of the vocal cord has been evaluated in this longitudinal epidemiological study. Patients have been followed up until the end of 1993 by examinations done once a month (first year), every three months (years 2 to 4), every six months (years 5 to 8), and then once a year. Life-tables have been computed according to Kaplan and Meier and raw survival has been 90.0%. Considering only the mortality due to any type of neoplastic disease, the survival reached 93.6%. Finally, considering only deaths due to recurrences or metastases of the primary tumor, the survival rate was 95.5%. Mortality after the first recurrence was 27.3%, after a second recurrence 50.0%. A correlation between number of cigarettes smoked and the risk of recurrence of the tumor could be observed (p < 0.01), while gross appearance and histologic grading of the vocal cord carcinoma proved to be uncorrelated with the risk of recurrences.
authors.affiliation: 1st Department of Otorhinolaryngology, University of Milan, IRCCS Ospedale Maggiore, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Broich
authors.forename: P
authors.initials: P
authors.lastname: Capaccio
authors.forename: F
authors.initials: F
authors.lastname: Ottaviani
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary / Q000628:therapy; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D014827:Vocal Cords