title: [Structure-activity relations of isochromanylpenicillins].
abstract: Isochroman is substituted and bound to 6-aminopenicillanic acid either directly or by a spacer in 1-position. In addition to the isochromans two homoisochromans are tested. The activities of the new penicillins against grampositive and gramnegative bacteria are compared with those of benzylpenicillin.
authors.affiliation: Institut für Pharmazeutische Chemie, Westfälischen Wilhelms-Universität, Münster.
authors.forename: B
authors.initials: B
authors.lastname: Unterhalt
authors.forename: B
authors.initials: B
authors.lastname: Nocon
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010400:Penicillin G / Q000737:chemistry / Q000494:pharmacology; D010406:Penicillins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D010406:Penicillins; D010400:Penicillin G
vernacular_title: Struktur-Wirkungs-Beziehungen an Isochromanylpenicillinen.