[Differential effect of estrogens in target tissues].
Using ER 1D5 new antibody it is shown that the estrogen receptor has an extra-nuclear localisation in vascular cells. This work exhibits, moreover, that the polymorphism of the estrogen receptor is in part regulated at the translation step.
Barraille
P
P
Laboratoire d'endocrinologie et communication cellulaire INSERM U 397, Institut L. Bugnard, CHU Rangueil, Touluse.
Pizzinat
N
N
Bayard
F
F
Faye
J C
JC
D000818:Animals; D000911:Antibodies, Monoclonal; D001011:Aorta / Q000166:cytology; D004730:Endothelium, Vascular / Q000737:chemistry*; D004967:Estrogens / Q000502:physiology*; D007150:Immunohistochemistry; D009131:Muscle, Smooth, Vascular / Q000166:cytology; D011110:Polymorphism, Genetic / Q000235:genetics*; D014176:Protein Biosynthesis; D051381:Rats; D017208:Rats, Wistar; D011960:Receptors, Estrogen / Q000032:analysis* / Q000187:drug effects / Q000235:genetics*
D000911:Antibodies, Monoclonal; D004967:Estrogens; D011960:Receptors, Estrogen
Action différentielle des oestrogènes selon les tissus cibles.