title: Plasma somatostatin levels in ulcerative colitis.
abstract: The circadian (24 hour) rhythmicity of somatostatin in healthy subjects and patients with ulcerative colitis (UC) was studied and established. UC patients were found to have a higher 24-hour amplitude, a higher average level and a longer peak level phase of plasma somatostatin. This finding may indicate a defensive role of somatostatin in inflammatory bowel disease.
authors.affiliation: 1st Department of Internal Medicine, Comenius University, Bratislava, Slovak Republic.
authors.forename: J
authors.initials: J
authors.lastname: Payer
authors.forename: M
authors.initials: M
authors.lastname: Huorka
authors.forename: I
authors.initials: I
authors.lastname: Duris
authors.forename: M
authors.initials: M
authors.lastname: Mikulecky
authors.forename: H
authors.initials: H
authors.lastname: Kratochvílová
authors.forename: P
authors.initials: P
authors.lastname: Ondrejka
authors.forename: L
authors.initials: L
authors.lastname: Lukác
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002940:Circadian Rhythm; D003093:Colitis, Ulcerative / Q000097:blood* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013004:Somatostatin / Q000097:blood*
chemical_list: D013004:Somatostatin