title: Determination of normal human fetal immunoglobulin M levels.
abstract: Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.
authors.affiliation: Department of Obstetrics & Gynecology, University of Virginia Health Sciences Center, Charlottesville.
authors.forename: D J
authors.initials: DJ
authors.lastname: Vick
authors.forename: W A
authors.initials: WA
authors.lastname: Hogge
authors.forename: D E
authors.initials: DE
authors.lastname: Normansell
authors.forename: B J
authors.initials: BJ
authors.lastname: Burkett
authors.forename: G M
authors.initials: GM
authors.lastname: Harbert
mesh_terms: D017218:Cordocentesis; D005260:Female; D005312:Fetal Blood / Q000276:immunology*; D005315:Fetal Diseases / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D005865:Gestational Age; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007231:Infant, Newborn; D007234:Infant, Premature; D007239:Infections / Q000097:blood / Q000175:diagnosis / Q000196:embryology / Q000276:immunology; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012044:Regression Analysis
chemical_list: D007075:Immunoglobulin M