title: [Lead poisoning in children from the industrial region of Silesia--hematologic indices].
abstract: In the paper, the basic parameters of blood morphologic pattern were assessed in school children exposed to toxic heavy metal emission. The studies included 323 children aged from 7 to 14 years, living in the region of emissions of the Mining-Ironworks Complex "Bolesław" in Bukowno. In these children haemoglobin concentration, haematocrit and erythrocyte and leucocyte counts were determined using routine laboratory tests. The obtained results were compared with corresponding results in the control group which consisted of 163 children of either sex living in a control region without exposure to heavy metals. In the studied group in most age subgroups significant decreases of erythrocyte count haemoglobin concentration and increases of haematocrit value were observed in comparison to the control group. At the same time, in these children, ten times higher, in relation to the control group, incidence was found of haemoglobin concentrations below 120 g/l, characteristic of anaemia. As it seems, one of important factors causing the decrease of the value of the parameters of blood morphologic pattern in the studied children is chronic microintoxication with lead, manifesting itself as significantly increased concentration of delta-amino-laevulinic acid in urine which is a sensitive marker of this intoxication.
authors.affiliation: IV Katedry i Kliniki Pediatrii Slaskiej Ak. Med., Chorzwie.
authors.forename: M
authors.initials: M
authors.lastname: Sada-Cieślar
authors.forename: B
authors.initials: B
authors.lastname: Mazur
authors.forename: Z
authors.initials: Z
authors.lastname: Buszman
authors.forename: G
authors.initials: G
authors.lastname: Cieślar
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D004785:Environmental Pollutants / Q000009:adverse effects*; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007855:Lead Poisoning / Q000097:blood* / Q000209:etiology; D007958:Leukocyte Count; D008297:Male; D008403:Mass Screening / Q000379:methods; D008669:Metallurgy
chemical_list: D004785:Environmental Pollutants; D006454:Hemoglobins
vernacular_title: Intoksykacja ołowiowa u dzieci w wielkoprzemysłowym rejonie ślaska--wskaźniki hematologiczne.