title: Hydrolysis of sucrose octa-acetate: qualitative differences in taster and demistaster avoidance phenotypes.
abstract: Calcium hydroxide and sodium hydroxide were used to hydrolyse sucrose octa-acetate (SOA) as a means of evaluating the taster (Soaa) and demitaster (Soac) allelic phenotypes of the genetic locus Soa. The SWR/J (taster) inbred strain and the B6.SW Soaa (taster) congenic strain were demonstrated to cease avoiding upon nearly complete hydrolysis of 10(-5) M SOA with calcium hydroxide or sodium hydroxide and of 10(-4) M SOA with calcium hydroxide. The BALB/cByJ, C3HeB/FeJ and DBA/2J (demitaster) inbred strains were demonstrated to cease avoiding after only a partial hydrolysis of 10(-3) M SOA using calcium hydroxide. It is suggested that specificity for the number or placement of the acetates of SOA underlies the difference between the taster and demitaster phenotypes.
authors.affiliation: Department of Psychology, Florida State University, Tallahassee 32306-1501, USA.
authors.forename: C G
authors.initials: CG
authors.lastname: Capeless
authors.forename: J D
authors.initials: JD
authors.lastname: Boughter
authors.forename: G
authors.initials: G
authors.lastname: Whitney
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D002126:Calcium Hydroxide; D005260:Female; D005518:Food Preferences; D006868:Hydrolysis; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D010641:Phenotype; D012972:Sodium Hydroxide; D013045:Species Specificity; D013395:Sucrose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D013649:Taste / Q000187:drug effects / Q000235:genetics*; D013652:Taste Threshold / Q000502:physiology
chemical_list: C026879:sucrose octaacetate; D012972:Sodium Hydroxide; D013395:Sucrose; D002126:Calcium Hydroxide