title: Activity of praziquantel (0.5 mg kg-1) against Anoplocephala perfoliata (Cestoda) in equids.
abstract: Praziquantel injectable formulation was administered at 0.5 mg k-1 per os to 24 equids naturally infected with 1-183 (average 40) Anoplocephala perfoliata. Drug activity was evaluated by a modified critical test method with necropsy 24 h after treatment. There was variable efficacy of 0-100% (aggregate average 85%); for 18 equids, 93-100%, for three equids, 70-85%, and for three equids, 0-20%.
authors.affiliation: Department of Veterinary Science, University of Kentucky, Lexington 40546-0099, USA.
authors.forename: E T
authors.initials: ET
authors.lastname: Lyons
authors.forename: S C
authors.initials: SC
authors.lastname: Tolliver
authors.forename: S
authors.initials: S
authors.lastname: Stamper
authors.forename: J H
authors.initials: JH
authors.lastname: Drudge
authors.forename: D E
authors.initials: DE
authors.lastname: Granstrom
authors.forename: S S
authors.initials: SS
authors.lastname: Collins
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002589:Cestoda / Q000302:isolation & purification; D002590:Cestode Infections / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases; D006736:Horses; D007413:Intestinal Mucosa / Q000469:parasitology / Q000473:pathology; D008297:Male; D009919:Orchiectomy; D011223:Praziquantel / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D011223:Praziquantel