title: Detection of Cryptococcus neoformans in bronchial lavage cytology: report of four cases.
abstract: Four cases of pulmonary cryptococcosis were diagnosed by cytological detection of Cryptococcus neoformans in bronchial lavage. Three patients had underlying diseases, but not HIV infection. The chest X-rays showed 2 patients with nodular lesions and 2 with cavitary lesions. The cryptococcal antigen in the serum was positive in all four patients. In the cytology of bronchial lavage, Cryptococcus neoformans was detected after period-acid-Schiff (PAS) staining and was cultured in Sabouraud-dextrose agar. The cytology of bronchial lavage is useful for the rapid diagnosis of pulmonary cryptococcosis.
authors.affiliation: Sasebo General Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Maesaki
authors.forename: S
authors.initials: S
authors.lastname: Kohno
authors.forename: H
authors.initials: H
authors.lastname: Mashimoto
authors.forename: J
authors.initials: J
authors.lastname: Araki
authors.forename: S
authors.initials: S
authors.lastname: Asai
authors.forename: K
authors.initials: K
authors.lastname: Hara
mesh_terms: D000328:Adult; D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000382:microbiology*; D003453:Cryptococcosis / Q000175:diagnosis* / Q000382:microbiology; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged