title: Cannalicular occlusion with cyanoacrylate adhesive: a new treatment for the dry eye.
abstract: One hundred microlitres (0.1 ml) of N-butyl cyano-acrylate adhesive was injected into the inferior cannaliculus of 8 patients with dry eye. The adhesive induced total (upper and lower) cannalicular occlusion in each patient which has not resolved to date (mean follow-up 15.2 months, range 11-19 months). Complications were minor and not specific to use of this adhesive. It is hoped that its ultimate reversibility will make the technique suitable for younger patients with dry eye.
authors.affiliation: University of Bristol, Department of Ophthalmology, Bristol Eye Hospital, UK.
authors.forename: J P
authors.initials: JP
authors.lastname: Diamond
authors.forename: J E
authors.initials: JE
authors.lastname: Morgan
authors.forename: J
authors.initials: J
authors.lastname: Virjee
authors.forename: D L
authors.initials: DL
authors.lastname: Easty
mesh_terms: D000368:Aged; D003487:Cyanoacrylates / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014463:Ultrasonography; D014985:Xerophthalmia / Q000628:therapy*
chemical_list: D003487:Cyanoacrylates