title: Taurine content in breast milk of Mexican women from urban and rural areas.
abstract: The concentration of the most abundant free amino acids in breast milk, taurine, glutamic acid, glycine + threonine, alanine and glycine was measured in breast milk samples obtained from Mexican women from an urban population (38 samples) and from a rural population (106 samples). Free amino acid levels including taurine in the urban group were essentially similar to those reported in samples from American and Canadian women (taurine concentration: 332-357 nmol/ml) but significantly lower content of taurine (237-259 nmol/ml) was found in the rural group. The only other significant difference between the two groups was a 32% higher concentration of alanine in the rural group as compared to the urban group. The observed differences may result from a lower dietary intake of taurine containing food in the rural group as this group reported a restricted consumption of meat, the most abundant dietary source of taurine. Because taurine synthesis is low in primates including human, a decreased external supply of taurine may explain the observed reduction in the taurine content of milk. The increase in alanine may represent a compensatory mechanism for the decrease in taurine.
authors.affiliation: Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, D. F., México.
authors.forename: H
authors.initials: H
authors.lastname: Pasantes-Morales
authors.forename: I
authors.initials: I
authors.lastname: López
authors.forename: A
authors.initials: A
authors.lastname: Ysunza
mesh_terms: D000596:Amino Acids / Q000032:analysis; D005260:Female; D006801:Humans; D008800:Mexico; D008895:Milk, Human / Q000737:chemistry*; D012424:Rural Population; D013654:Taurine / Q000032:analysis*; D014505:Urban Population
chemical_list: D000596:Amino Acids; D013654:Taurine