[Ischemic heart disease with significant coronary stenosis and insulin resistance].
The authors examined a group of 22 patients with significant stenoses revealed on coronarographic examination. None of the patients were diabetic. Hyperinsulinaemia was found in 12 patients (54.5%). The hyperinsulinaemic and normoinsulinaemic groups differed significantly as to the type of obesity expressed by the W/H ratio, the incidence of hypertension and triglyceride levels. The authors discuss the direct participation of insulin resistance and compensatory hyperinsulinism in the pathogenesis of atherosclerosis and its participation in the manifestation of associated risk factors (dyslipidaemia, hypertension, obesity and NIDDM).
Okapcová
J
J
Interná klinika A, Nemocnica F.D. Roosevelta, Banská Bystrica.
Meciar
P
P
Skamla
J
J
Koróny
S
S
D000328:Adult; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000000981:diagnostic imaging / Q000503:physiopathology*
D007328:Insulin
Ischemická choroba srdca so signifikantnými koronárnymi stenózami a inzulínová rezistencia.