title: Solvation of platinum anti-cancer drugs in methanol-water mixtures.
abstract: Solubilities and transfer chemical potentials of carboplatin, cisplatin, iproplatin, and several related platinum complexes have been determined in methanol-water mixtures. The range of solvation behaviour is discussed in relation to possible oral administration of complexes of this type.
authors.affiliation: Chemistry Department, University of Leicester, UK.
authors.forename: J
authors.initials: J
authors.lastname: Burgess
authors.forename: D N
authors.initials: DN
authors.lastname: Drasdo
authors.forename: M S
authors.initials: MS
authors.lastname: Patel
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry*; D016190:Carboplatin / Q000737:chemistry; D002945:Cisplatin / Q000737:chemistry; D009944:Organoplatinum Compounds / Q000737:chemistry*; D012995:Solubility
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; C023359:iproplatin; D016190:Carboplatin; D002945:Cisplatin