title: Glass-ceramic-coated titanium hip endoprosthesis. Experimental study in rabbits.
abstract: Titanium alloy hip endoprostheses coated with a bioactive glass ceramic (BGC) were followed in rabbits. All test endoprostheses remained stable, and image analysis showed an average of 78% bonding of the BGC-coated implants to bone at 52 weeks. The uncoated Ti-alloy controls demonstrated an average of 37% bone coverage after 52 weeks. By scanning electron microscopy the thickness of the BGC reaction layer was found to stabilize at 60 microns after bioactive bone bonding. The results indicate that the BGC coating must be thicker than the reaction layer to prevent detachment from the core metal.
authors.affiliation: Department of Clinical Medicine, University of Tampere, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Pajamäki
authors.forename: S
authors.initials: S
authors.lastname: Lindholm
authors.forename: O
authors.initials: O
authors.lastname: Andersson
authors.forename: K
authors.initials: K
authors.lastname: Karlsson
authors.forename: A
authors.initials: A
authors.lastname: Yli-Urpo
authors.forename: R P
authors.initials: RP
authors.lastname: Happonen
mesh_terms: D000497:Alloys; D000818:Animals; D002516:Ceramics; D005898:Glass; D006622:Hip Prosthesis; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D014025:Titanium
chemical_list: D000497:Alloys; D014025:Titanium