title: Two cases of neurological manifestations in eosinophilia: variations of one disease?
abstract: The hypereosinophilic syndrome is characterized by a long-lasting increase in circulating eosinophils in the absence of a definable etiology and by manifestations of multisystem involvement. It must be differentiated from the eosinophilia-myalgia syndrome related to the ingestion of L-tryptophan, although the clinical features may be similar. Two patients with hypereosinophilia not related to L-tryptophan intake are described who both became clinically symptomatic with neurological manifestations of acute and subacute onset: one with eosinophilic fasciitis and the other with painful polyneuropathy. Both responded well to corticosteroids.
authors.affiliation: Neurologische Universitätsklinik Bonn, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Ostrowitzki
authors.forename: S
authors.initials: S
authors.lastname: Zierz
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications* / Q000175:diagnosis; D005208:Fasciitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D010523:Peripheral Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*