title: [Mutations of the hMSH2 and hMlH1 genes are responsible for 90% of hereditary colorectal carcinomas].
authors.affiliation: Ruhr-Universität Bochum, Medizinische Klinik, Knappschaftskrankenhaus.
authors.forename: S A
authors.initials: SA
authors.lastname: Hahn
authors.forename: W H
authors.initials: WH
authors.lastname: Schmiegel
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D002889:Chromosomes, Human, Pair 2; D002893:Chromosomes, Human, Pair 3; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics*; D004252:DNA Mutational Analysis; D004260:DNA Repair / Q000235:genetics; D004268:DNA-Binding Proteins; D005656:Fungal Proteins / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein; D009363:Neoplasm Proteins / Q000235:genetics*; D009687:Nuclear Proteins
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D005819:Genetic Markers; C501486:MLH1 protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein
vernacular_title: Mutationen der Gene hMSH2 und hMLH1 sind für 90% der hereditären kolorektalen Karzinome verantwortlich.