title: Balloon-expandable stent repair of severe coarctation of aorta.
abstract: Experimental studies have shown that stents implanted at the aorta become incorporated within the aortic wall and can be further expanded in growing animals. This study evaluates the feasibility and immediate results of balloon-expandable stent implantation in 10 patients with severe coarctation of aorta. The ages of the patients ranged from 1 month to 43 years; 1 was an infant, 8 were children (mean age 5.3 +/- 4 years), and 1 was an adult. All had an unfavorable anatomy for balloon angioplasty; 9 had isthmus hypoplasia. Balloon predilation was first performed and its immediate effect evaluated. Then a balloon-expandable stent that was 30 mm long and covered the isthmus and coarctation levels was deployed, and it was further expanded to the preselected final diameter (12 +/- 4 mm). A final hemodynamic and angiographic evaluation was then obtained. Full deployment of an incompletely expanded and distally displaced stent in the infant led to aortic disruption that was controlled by a second stent covering the disrupted zone and the isthmus. After balloon angioplasty alone was done, the mean gradient (43 +/- 12 vs 31 +/- 10 mm Hg) and the percentage stenosis (72% +/- 11% vs 54% +/- 11%) had an insufficient decrease. However, after stent implantation was done, the gradient almost disappeared (mean 2 +/- 3 mm Hg). The angiographic stenosis disappeared in 7 patients and was markedly reduced in 3. The ratio of isthmus/descending aorta changed from 0.65 +/- 0.14 to 1 +/- 0.08 (p < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Servicio de Cardiología, Hospital Reina Sofia, University of Córdoba, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Suárez de Lezo
authors.forename: M
authors.initials: M
authors.lastname: Pan
authors.forename: M
authors.initials: M
authors.lastname: Romero
authors.forename: A
authors.initials: A
authors.lastname: Medina
authors.forename: J
authors.initials: J
authors.lastname: Segura
authors.forename: D
authors.initials: D
authors.lastname: Pavlovic
authors.forename: C
authors.initials: C
authors.lastname: Martinez
authors.forename: I
authors.initials: I
authors.lastname: Tejero
authors.forename: J
authors.initials: J
authors.lastname: Perez Navero
authors.forename: F
authors.initials: F
authors.lastname: Torres
mesh_terms: D000208:Acute Disease; D000328:Adult; D001017:Aortic Coarctation / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D001027:Aortography; D006328:Cardiac Catheterization; D002404:Catheterization / Q000009:adverse effects / Q000379:methods; D002648:Child; D002675:Child, Preschool; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome