[Hypoplastic leukemia achieved long-term remission with low-dose cytosine arabinoside].
A 74-year-old woman was admitted in October 1988 with anemia and leukocytopenia. Hematologic investigations established a diagnosis of hypoplastic acute leukemia. She received a low dose of cytosine arabinoside (LDAC: 10 mg/m2 every 12 hours) subcutaneously for 21 days and achieved complete remission (CR) one month later. After one course of LDAC of 14 days, she received LDAC of 21 days every 5 to 6 months as maintenance therapy till April 1993. She has been in remission for 6 years. Intensification therapy with LDAC every 5 to 6 months might be useful in maintaining remission for hypoplastic acute leukemia.
Fujisawa
S
S
Department of Hematology and Chemotherapy, Kanagawa Cancer Center.
Kanamori
H
H
Noguchi
T
T
Maruta
A
A
Ogawa
K
K
Sakai
R
R
Taguchi
J
J
Tomita
N
N
Kodama
F
F
Okubo
T
T
D000368:Aged; D000740:Anemia / Q000150:complications; D003561:Cytarabine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D007970:Leukopenia / Q000150:complications; D012074:Remission Induction
D003561:Cytarabine