title: The formation of peroxynitrite in vivo from nitric oxide and superoxide.
abstract: Peroxynitrite is predicted to be formed in vivo from the reaction of nitric oxide and superoxide. Nitric oxide at concentrations as low as 3 nM is expected to compete efficiently for superoxide near the surface of endothelial cells, based on competition kinetics.
authors.affiliation: Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA.
authors.forename: G L
authors.initials: GL
authors.lastname: Squadrito
authors.forename: W A
authors.initials: WA
authors.lastname: Pryor
mesh_terms: D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D007700:Kinetics; D009566:Nitrates / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
chemical_list: D009566:Nitrates; D013481:Superoxides; C039642:peroxynitric acid; D009569:Nitric Oxide