title: Isolation and structure determination of a new marine neurotoxin from the New Zealand shellfish, Austrovenus stutchburyi.
abstract: A new marine neurotoxin was isolated from a water extract of the New Zealand shellfish, Austrovenus stutchburyi, by chromatography on columns of Sephadex G-15 and LH-20, followed by reverse-phase HPLC. It was identified as (4-methoxycarbonylbutyl)trimethyl-ammonium chloride, and this was confirmed by synthesis.
authors.affiliation: School of Pharmaceutical Science, University of Shizuoka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ishida
authors.forename: A
authors.initials: A
authors.lastname: Nozawa
authors.forename: H
authors.initials: H
authors.lastname: Nukaya
authors.forename: K
authors.initials: K
authors.lastname: Tsuji
authors.forename: H
authors.initials: H
authors.lastname: Kaspar
authors.forename: N
authors.initials: N
authors.lastname: Berkett
authors.forename: T
authors.initials: T
authors.lastname: Kosuge
mesh_terms: D000818:Animals; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D009498:Neurotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D009520:New Zealand; D012758:Shellfish; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D008387:Marine Toxins; D009498:Neurotoxins