title: Effective use of cyclosporin in sarcoidosis: a treatment strategy based on computed tomography scanning.
abstract: Cyclosporin was used successfully in a patient with severe pulmonary sarcoidosis, a poor response and unacceptable side-effects from corticosteroid therapy. Computed tomography (CT) scanning initially suggested reversible disease, and subsequently detected improvement earlier than other indices of disease activity. This information was critical in the decision to commence and to continue cyclosporin. The literature on the use of cyclosporin in sarcoidosis is reviewed.
authors.affiliation: Royal Brompton National Heart and Lung Hospital, London, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: O'Callaghan
authors.forename: A U
authors.initials: AU
authors.lastname: Wells
authors.forename: A
authors.initials: A
authors.lastname: Lalvani
authors.forename: P D
authors.initials: PD
authors.lastname: Dhillon
authors.forename: D M
authors.initials: DM
authors.lastname: Hansell
authors.forename: D N
authors.initials: DN
authors.lastname: Mitchell
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D017565:Sarcoidosis, Pulmonary / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D016572:Cyclosporine