title: Advances in Wegener's granulomatosis.
abstract: The upper airway is usually the source of initial concern, but lung involvement eventually emerges. Thus, the disease is a reminder that the diagnosis of persistent upper airway problems should have more than a regional focus. Combinations of glucocorticoids and cytotoxic drugs have yielded a dramatic improvement in survival.
authors.affiliation: Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, USA.
authors.forename: G S
authors.initials: GS
authors.lastname: Hoffman
mesh_terms: D000293:Adolescent; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D015267:Churg-Strauss Syndrome / Q000175:diagnosis; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D011379:Prognosis
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D015415:Biomarkers