title: [Observation of cochlear microcirculation in experimental endolymphatic hydrops].
abstract: 30 guinea pigs were made as a model of endolymphatic hydrops by obliteration of endolymphatic sac and duct. Cochlear microcirculation of the lateral wall in the third turn was observed and recorded. The diameters and velocities of the vessels were analysed in IBAS image system. The stria vascular vessels and spiral ligament vessels were analysed respectively. The data showed: 1. 1, 2 and 3 months after operation, the diameter of SLV averaely decreased 0.80 microns, 0.87 microns, 1.21 microns (P < 0.05) respectively and velocity decreased 100.8 microns/s, 141.0 microns/s, 136.0 microns/s (P < 0.05) respectively. 2. The diameter of SVV dilated 3 months after operation. With the elapse of time, SVV had a dilation tendency. These indicated that hydrops effect different changes in SLV and SVV. The overpressure of endolymphatic fluid may be the possible cause of changes in SVV and SLV.
authors.affiliation: PLA General Hospital, Beijing.
authors.forename: C
authors.initials: C
authors.lastname: Zhou
authors.forename: S
authors.initials: S
authors.lastname: Zhang
authors.forename: B
authors.initials: B
authors.lastname: Hu
mesh_terms: D000818:Animals; D003051:Cochlea / Q000098:blood supply*; D003053:Cochlear Duct / Q000098:blood supply / Q000473:pathology; D018159:Endolymphatic Hydrops / Q000473:pathology / Q000503:physiopathology*; D006168:Guinea Pigs; D008297:Male; D008833:Microcirculation; D013316:Stria Vascularis / Q000473:pathology / Q000502:physiology