Increased technetium-99m-HMPAO uptake in grade II astrocytoma.
Most brain tumors show decreased uptake of blood flow tracers in brain SPECT imaging and in some cases meningiomas show increased uptake, mainly associated with high regional blood flow values. A reason for regionally increased tracer uptake is partial epilepsy when a tracer is injected during the ictal phase. We present a case of a histologically proven Grade II astrocytoma in the mesial part of the left temporal lobe that caused complex partial seizures. After tracer injection during a phase without signs of clinical seizure, markedly increased uptake of 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) occurred, although the tumor was partially calcified.
Grünwald
F
F
Department of Nuclear Medicine, University of Bonn, Germany.
Menzel
C
C
Pietsch
T
T
Pavics
L
L
Hufnagel
A
A
Biersack
H J
HJ
D000328:Adult; D001254:Astrocytoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D017029:Epilepsy, Complex Partial / Q000209:etiology; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D013702:Temporal Lobe / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime