Differences in nonenzymatic glycation of histones.
Time course of glucose binding by histone Hl and total histones was followed in isolated histone preparations and in thymus nuclei. In both cases the uptake of glucose by Hl was surprisingly high in contrast to a much lower uptake of glucose by total histones. DNA is not implicated in glycation of histones in nuclei.
Lakatos
A
A
Department of Clinical Chemistry, University Medical School, Pécs, Hungary.
Kiss
N
N
Jobst
K
K
D000818:Animals; D002417:Cattle; D002467:Cell Nucleus / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D013950:Thymus Gland / Q000378:metabolism
D006657:Histones; D005947:Glucose