title: Exploration of the common bile duct for stones: the influence of the flexible choledochoscope and perioperative antibiotic prophylaxis.
abstract: A retrospective study of 110 patients, out of a total of 743 open cholecystectomies, who have undergone common bile duct (CBD) exploration for stones between 1985 and 1990. CBD exploration was performed in the presence of abnormal peroperative cholangiogram in 86 (78%) patients. The remaining 24 patients were known to have either an abnormal preoperative ERCP or palpable ductal stones at the time of surgery. Post exploratory choledochoscopy was performed as an additional completion procedure in 58 (53%) patients and it identified further stones in 28 (48.3%) of these patients. There were three patients in whom no stones were identified on exploration of the CBD. Documented evidence of peroperative antibiotic prophylaxis was obtained in 78 (71%) patients. A total of 27 (24.5%) patients developed complications including seven (6.4%) patients with retained stones. In four of these patients with retained stones, flexible choledochoscopy was undertaken as an additional completion procedure to ensure ductal clearance. Cardiorespiratory and septic complications were the next most common problems occurring in 6.5% and 5.4% respectively, of patients reviewed. In conclusion, the retained stone rate has fallen from 14% in 1987 to 6.4% in this study. The choledochoscope has influenced this as it identified further residual stones following conventional exploration. The sepsis rate has also fallen from 19.5% to 4.5% in this study. We believe this is due to the use of antibiotic prophylaxis.
authors.affiliation: East Glamorgan Hospital, Pontypridd, Wales, UK.
authors.forename: T O
authors.initials: TO
authors.lastname: Oshodi
authors.forename: A P
authors.initials: AP
authors.lastname: Sandison
authors.forename: W G
authors.initials: WG
authors.lastname: Sheridan
authors.forename: M E
authors.initials: ME
authors.lastname: Foster
authors.forename: M H
authors.initials: MH
authors.lastname: Lewis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002511:Cephalosporins / Q000627:therapeutic use; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002763:Cholecystectomy; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D016145:Endoscopy, Digestive System / Q000295:instrumentation*; D005260:Female; D042882:Gallstones / Q000601:surgery*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D011292:Premedication; D012189:Retrospective Studies
chemical_list: D002511:Cephalosporins; D008795:Metronidazole