title: Particle-fluid suspension model of blood flow through stenotic vessels with applications.
abstract: The present study deals with the problem of blood flow through stenotic vessels when blood is represented by a particle-fluid suspension model, i.e. a suspension of red blood cells in plasma. The expression for the dimensionless resistance to flow, the wall shear stress, and the shearing stress on the wall at the maximum height of the stenosis are derived. The results obtained in the analysis are discussed in brief, both qualitatively and quantitatively by comparison with other theories. It is observed that the magnitudes of the blood flow characteristics significantly increase with an increase in the red cell concentration. The importance of the decreasing vessel diameter is also pointed out. Finally, to observe the biological relevance of the analysis, the results obtained are used to compute the blood flow characteristics for normal and diseased blood using the experimental data from published literature and results are compared with those computed using the present theoretical approach.
authors.affiliation: Department of Mathematics and Astronomy, University of Lucknow, India.
authors.forename: V P
authors.initials: VP
authors.lastname: Srivastava
mesh_terms: D000465:Algorithms; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D001809:Blood Viscosity; D003251:Constriction, Pathologic / Q000503:physiopathology; D004911:Erythrocyte Volume; D004912:Erythrocytes / Q000502:physiology; D006400:Hematocrit; D006402:Hematologic Diseases / Q000503:physiopathology; D018056:Hemorheology; D006801:Humans; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D010949:Plasma / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology