[Polymer-containing eye drops. II. Isotonicity and pH adjustment of polymer solutions].
Authors studied potentials for isotonizability and isohydria adjustment of viscous eye-drops. Various non-ionic, anionic, linear chain, and/or crosslinked polymers were applied in order to increase viscosity. They have found that rheological features of the solutions do not change either upon the addition of electrolytes or upon change in pH value. Modification in equilibrium viscosity values indicate the onset of dehydration. Such change occurs in concentrated polymer solutions only.
Ugriné-Hunyadvári
E
E
Szent-Györgyi Albert Orvostudományi Egyetem Gyógyszertechnológiai Intézet, Szeged.
Kissné Koczka
C
C
D004573:Electrolytes; D006863:Hydrogen-Ion Concentration; D009883:Ophthalmic Solutions; D009994:Osmolar Concentration; D011108:Polymers; D012996:Solutions; D013329:Structure-Activity Relationship
D004573:Electrolytes; D009883:Ophthalmic Solutions; D011108:Polymers; D012996:Solutions
Polimer tartalmú szemcseppek vizsgálata. II. Polimer oldatok izotonizálhatósága és pH beállítása.