Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.
Basco
L K
LK
Centre de Génétique Moléculaire, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.
Eldin de Pécoulas
P
P
Wilson
C M
CM
Le Bras
J
J
Mazabraud
A
A
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018432:Drug Resistance, Multiple; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics*; D017354:Point Mutation; D002727:Proguanil; D011739:Pyrimethamine / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*; D013940:Thymidylate Synthase / Q000235:genetics*; D014227:Triazines / Q000494:pharmacology*
D014227:Triazines; C026009:cycloguanil; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D002727:Proguanil; D011739:Pyrimethamine