title: [Clinical analysis of 60 cases of nosocomal pneumonias].
abstract: This article gives a clinical analysis upon 60 cases of nosocomial acquired pneumonia. All the patients are > 18 years old and the onset time ranged from 3 to 180 days after they were hospitalized with an average of 38.77 days, mostly 30 days after admission (27 cases, 49%). Among the primary diseases, the hematologic disorder (18 cases, 30%) rank the first, followed by cerebrovascular disease (9 cases, 15%) and connective tissue disease (8 cases, 13.3%), The common inducing factors are the using of corticosteroids and chemotherapy (34 cases, 58%), tracheotomy and tracheal cannula (7 cases, 11.6%). Fever occurs in 96% of the patients and cough 63.3%. The positive rate of sputum bacterial culture is 95.46%. Pseudomonas aeruginosa isolated in 25 cases (56.8%). and Klebsiella pneumoniae 18 cases (40%). P. aeruginosa shows resistant to the third generation of cefalosporins more than before, and is sensitive to ciprofloxacin and polymyxin B, while K. pneumoniae is resistant to many kinds of antibiotics, especially ampicilline and carbenicilline. The death rate of infection of P. aeruginosa is 58.33% (14/25) and that of K. pneumoniae is 60% (12/18), that of mixed infection is 66.67% (16/23).
authors.affiliation: Department of Respiratory Diseases, Peking Union Medical College Hospital, Beijin.
authors.forename: L
authors.initials: L
authors.lastname: Yu
authors.forename: Y L
authors.initials: YL
authors.lastname: Chen
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zhu
mesh_terms: D000328:Adult; D002939:Ciprofloxacin / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy; D007711:Klebsiella pneumoniae / Q000187:drug effects; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D011112:Polymyxin B / Q000627:therapeutic use; D011552:Pseudomonas Infections / Q000188:drug therapy*
chemical_list: D002939:Ciprofloxacin; D011112:Polymyxin B