[Evaluation of epithelial ovarian neoplasm immunologic reactivity using monoclonal antibodies].
The reactivity of five monoclonal antibodies against ovarian carcinoma-associated antigens (OC125, OV632, OV-TL3, 8C, 10B) on tissue sections of malignant and benign ovarian neoplasms was estimated and compared using PAP technique. The immunodiagnostic usefulness of OC125 and OV-TL3 antibodies in differentiation between serous and endometrioid ovarian carcinomas was indicated. OV632 monoclonal antibody appears to be a good marker for differentiation between malignant and benign changes in ovary. Difficulties in typing of monoclonal antibodies for immunodiagnostic purposes were pointed out.
Bar
J
J
Zakład Immunologii Nowotworów Akademii Medycznej we Wrocławiu.
Sobańska
E
E
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis*; D002277:Carcinoma / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D010049:Ovarian Diseases / Q000175:diagnosis; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm
Ocena reaktywności immunologicznej nabłonkowych nowotworów jajnika z uzyciem przeciwciał monoklonalnych.