Use of the GnRH agonist stimulation test in the diagnosis of ovarian remnant syndrome. A report of three cases.
Ovarian remnant syndrome is an uncommon problem that may follow bilateral oophorectomy. These patients may present with chronic pelvic pain or pelvic masses and may require surgery to confirm or exclude the diagnosis. In this report we describe the successful use of the gonadotropin releasing hormone agonist (GnRH-a) stimulation test to identify the presence of functioning ovarian tissue in three women with ovarian remnant syndrome who presented for evaluation of persistent chronic pelvic pain. In these cases the endogenous gonadotropin flare was able to stimulate the production of significant quantities of estradiol to confirm the diagnosis. The GnRH-a stimulation test may be a useful adjunct in the evaluation of women at risk for ovarian remnant syndrome prior to proceeding with surgery.
Scott
R T
RT
Department of Obstetrics and Gynecology, Wilford Hall Medical Center, Lackland Air Force Base, Texas, USA.
Beatse
S N
SN
Illions
E H
EH
Snyder
R R
RR
D000328:Adult; D004958:Estradiol / Q000097:blood*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D016729:Leuprolide; D010049:Ovarian Diseases / Q000175:diagnosis* / Q000209:etiology; D010052:Ovariectomy / Q000009:adverse effects*; D017699:Pelvic Pain; D013577:Syndrome
D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D016729:Leuprolide