title: Supratentorial low grade gliomas in adults. A retrospective analysis of 43 cases treated with surgery and radiotherapy.
abstract: Forty-three adults with histologically verified low grade gliomas, treated with post-operative radiotherapy between 1983 and 1991, were reviewed. Previous studies have identified age and extent of surgery as prognostic factors for survival. In this series, there was no significant difference between patients under 40 years of age and those 40 and over, nor was there a survival difference between those who had open biopsy and those who underwent subtotal/total resection. Patients with seizures preoperatively showed improvement in epileptic control at one year post-radiation. Clinical performance status and neurological deficit scoring indicated good preservation of function one year after radiation.
authors.affiliation: Department of Oncology, Middlesex Hospital, London, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Singer
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy* / Q000601:surgery*; D004388:Dura Mater; D005260:Female; D005910:Glioma / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology / Q000517:prevention & control; D016019:Survival Analysis; D016896:Treatment Outcome