Discovery of a better aspirin.
Isakson
P
P
Inflammatory Diseases Research, G.D. Searle and Monsanto Corporate Research, St. Louis, Missouri 63198, USA.
Seibert
K
K
Masferrer
J
J
Salvemini
D
D
Lee
L
L
Needleman
P
P
D000698:Analgesia; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D001169:Arthritis, Experimental / Q000188:drug therapy; D001241:Aspirin; D002351:Carrageenan; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D015195:Drug Design; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006801:Humans; D007249:Inflammation; D007527:Isoenzymes / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism
D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D002351:Carrageenan; D011451:Prostaglandin-Endoperoxide Synthases; D001241:Aspirin