title: [An anticoagulant from extracts of peony roots: its isolation and properties].
abstract: A protein-free anticoagulant preparation displaying anticoagulative but not fibrinolytic activity in vitro was isolated from peony. Electrophoretic, chromatographic, and spectral analyses revealed that this anticoagulant resembles animal heparin: it contains sulfur, carbon, and nitrogen in quantities characteristic of the latter. Plant heparin enhances anticoagulative and fibrinolytic plasma properties and decreases platelet aggregation. It may be used as a harmless and ecologically pure anticoagulant.
authors.forename: L A
authors.initials: LA
authors.lastname: Liapina
authors.forename: V S
authors.initials: VS
authors.lastname: Novikov
authors.forename: V E
authors.initials: VE
authors.lastname: Pastorova
authors.forename: M S
authors.initials: MS
authors.lastname: Uspenskaia
authors.forename: T Iu
authors.initials: TIu
authors.lastname: Smolina
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Liapin
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006487:Hemostasis / Q000187:drug effects; D008297:Male; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D051381:Rats
chemical_list: D000925:Anticoagulants; D010936:Plant Extracts
vernacular_title: Antikoagulant iz ékstraktov korneĭ pionov: poluchenie i svoĭstva.