Congestive heart failure caused by vitamin D deficiency?
We describe a child, 3.5 months old, with severe vitamin D deficiency, profound hypocalcaemia, hyperphosphataemia, dilated left ventricle, severely reduced myocardial contractility and congestive heart failure. She also had depressed thyroid function with subnormal thyroxine and non-detectable serum thyrotropin (TSH) levels. The child promptly responded to calcium infusions, conventional anticongestive therapy and calcitriol. She is now 3 years old and received no medication. Myocardial function is normal but she has motor delay. We believe that her transitory congestive heart failure was caused by severe vitamin D deficiency with profound hypocalcaemia.
Brunvand
L
L
Department of Paediatrics, Ullevål Hospital, Oslo, Norway.
Hågå
P
P
Tangsrud
S E
SE
Haug
E
E
D002117:Calcitriol / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D007223:Infant; D009200:Myocardial Contraction; D010710:Phosphates / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications* / Q000188:drug therapy
D010710:Phosphates; D002117:Calcitriol