[CT compared with SPECT in chronic recurrent pulmonary embolism: hyperdensities as signs of pulmonary artery hyperperfusion?].
Purpose of this study was to assess the aetiology of inhomogeneous lung parenchymal attenuation in patients with chronic pulmonary thromboembolism, presenting as sharply demarcated areas of increased and decreased density on computed tomography.


METHODS
In 52 patients with chronic pulmonary thromboembolism, computed tomography (CT) was compared with perfusion scintigraphy (including SPECT) and agreement was assessed: "good" (all hyperdense CT segments are perfused on scan), "moderate" or "poor" (one or two resp. three or more hyperdense CT segments are not perfused).


RESULTS
44 of the 52 patients showed an inhomogeneous pulmonary attenuation on CT. Correlation of hyperdense areas with perfused lung parenchyma was graded as "good" in 26 cases, "moderate" in 14 and "poor" in 4 cases. In 40 of these 44 patients, scintigraphy revealed additional perfusion defects in homogeneously lucent areas on CT. In 6 of 8 patients with entirely homogeneous lung density on CT, SPECT revealed perfusion defects.


CONCLUSIONS
In patients with chronic pulmonary thromboembolism, increased lung density on CT is caused by hyperperfused lung parenchyma distally to patent pulmonary arteries. SPECT proves to be more sensitive in diagnosing perfusion inhomogeneities.
Schwickert
H C
HC
Klinik für Radiologie, Universitätskiniken Mainz.
Kauczor
H U
HU
Piepenburg
R
R
Schweden
F
F
Schild
H H
HH
Iversen
S
S
Thelen
M
M
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003287:Contrast Media; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D012008:Recurrence; D012680:Sensitivity and Specificity; D013668:Technetium Tc 99m Aggregated Albumin; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods
D003287:Contrast Media; D013668:Technetium Tc 99m Aggregated Albumin; D007472:Iohexol; C038192:iopromide
CT im Vergleich mit SPECT bei chronisch rezidivierender Lungenembolie: Hyperdensien als Zeichen pulmonalarterieller Hyperperfusion?