Serotypes and antimicrobial susceptibility of Haemophilus influenzae.
During a one year prospective study of Haemophilus influenzae infections in patients treated in hospitals in the metropolitan area of Cape Town. H. influenzae type b accounted for 81.7% of 126 invasive isolates, whereas 86.1% of the 280 non-invasive isolates were non-typeable. Ampicillin resistance was detected among 10.8% of strains of which all but one produced beta-lactamase. All strains were susceptible to cefotaxime as were more than 95% to chloramphenicol, rifampicin, tetracycline but 20.4% were resistant to co-trimoxazole and 87.2% to erythromycin.
Hussey
G
G
Department of Paediatrics and Child Health, University of Cape Town, Somerset Hospital, Republic of South Africa.
Hitchcock
J
J
Hanslo
D
D
Coetzee
G
G
Van Schalkwyk
E
E
Pitout
J
J
Schaaf
H
H
D000328:Adult; D001168:Arthritis / Q000382:microbiology; D002439:Cefotaxime / Q000494:pharmacology; D002481:Cellulitis / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology; D006192:Haemophilus Infections / Q000453:epidemiology; D006193:Haemophilus influenzae / Q000145:classification* / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008581:Meningitis / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D011014:Pneumonia / Q000382:microbiology; D012137:Respiratory System / Q000382:microbiology; D012703:Serotyping; D013019:South Africa / Q000453:epidemiology; D001618:beta-Lactamases / Q000378:metabolism
D004917:Erythromycin; D001618:beta-Lactamases; D002439:Cefotaxime