[Effect of stress in early postnatal development on long-term changes in cellular immunity].
Using the model of colding stress in rats in early postnatal ontogeny, is has been established that the raise of PHA induced H-thymidine incorporation into the spleen cells and higher concentrations of corticosterone in the blood serum in adults. It is shown that stressing of animals (+5 + -0. +5 degrees C, 30 min) on the 4-9th day of postnatal life significantly alters the stress resctiveness in the adult animals.
Baieva
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D000818:Animals; D000831:Animals, Newborn; D003080:Cold Temperature / Q000009:adverse effects*; D003345:Corticosterone / Q000097:blood; D004247:DNA / Q000096:biosynthesis; D007030:Hypothalamo-Hypophyseal System / Q000276:immunology* / Q000378:metabolism; D007111:Immunity, Cellular; D008297:Male; D010913:Pituitary-Adrenal System / Q000276:immunology* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013312:Stress, Physiological / Q000276:immunology*; D013997:Time Factors
D004247:DNA; D003345:Corticosterone
Tryvali zminy klitynnoho imunitetu pry diĭ stresu u ranniĭ postnatalńyĭ period ontohenezu.