title: Expanded polytetrafluoroethylene (Gore-Tex Surgical Membrane) is superior to oxidized regenerated cellulose (Interceed TC7+) in preventing adhesions.
abstract: OBJECTIVE
  To compare the impact of expanded polytetrafluoroethylene (PTFE; Gore-Tex Surgical Membrane; W. L. Gore & Associates, Inc., Flagstaff, AZ) and oxidized regenerated cellulose (Interceed TC7, Johnson & Johnson Medical, Inc., Arlington, TX) on the development of postsurgical adhesions.
  
  
  METHODS
  A multicenter, nonblinded, randomized clinical trial.
  
  
  METHODS
  University medical centers.
  
  
  METHODS
  Each barrier was allocated randomly to the left or right sidewall of every patient.
  
  
  METHODS
  Thirty-two women with bilateral pelvic sidewall adhesions undergoing reconstructive surgery and second-look laparoscopy.
  
  
  METHODS
  Adhesion score (on a 0- to 11-point scale), the area of adhesion (cm2), and the likelihood of no adhesions.
  
  
  RESULTS
  The use of both barriers was associated with a lower adhesion score and area of adhesion postoperatively. However, those sidewalls covered with PTFE had a significantly lower adhesion score (0.97 +/- 0.30 versus 4.76 +/- 0.61 points, mean +/- SEM) and area of adhesion (0.95 +/- 0.35 versus 3.25 +/- 0.62 cm2). Overall, more sidewalls covered with PTFE had no adhesions (21 versus 7) and, when adhesions were present on the contralateral sidewall, the number of sidewalls covered with PTFE without adhesions was greater than those covered with oxidized regenerated cellulose (16 versus 2).
  
  
  CONCLUSIONS
  Expanded polytetrafluoroethylene was associated with fewer postsurgical adhesions to the pelvic sidewall than oxidized regenerated cellulose.
authors.affiliation: Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: A F
authors.initials: AF
authors.lastname: Haney
authors.forename: J
authors.initials: J
authors.lastname: Hesla
authors.forename: B S
authors.initials: BS
authors.lastname: Hurst
authors.forename: L M
authors.initials: LM
authors.lastname: Kettel
authors.forename: A A
authors.initials: AA
authors.lastname: Murphy
authors.forename: J A
authors.initials: JA
authors.lastname: Rock
authors.forename: G
authors.initials: G
authors.lastname: Rowe
authors.forename: W D
authors.initials: WD
authors.lastname: Schlaff
mesh_terms: D000293:Adolescent; D000328:Adult; D002482:Cellulose / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010084:Oxidation-Reduction; D011138:Polytetrafluoroethylene / Q000627:therapeutic use*; D012086:Reoperation; D000267:Tissue Adhesions / Q000517:prevention & control*
chemical_list: D011138:Polytetrafluoroethylene; D002482:Cellulose