title: Inhibition of CoA-independent transacylase reduces inflammatory lipid mediators.
authors.affiliation: Department of Pharmacology, SmithKline Beecham Pharmaceuticals, King of Prussia, PA 19406, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Winkler
authors.forename: A N
authors.initials: AN
authors.lastname: Fonteh
authors.forename: C M
authors.initials: CM
authors.lastname: Sung
authors.forename: L
authors.initials: L
authors.lastname: Huang
authors.forename: M
authors.initials: M
authors.lastname: Chabot-Fletcher
authors.forename: L A
authors.initials: LA
authors.lastname: Marshall
authors.forename: F H
authors.initials: FH
authors.lastname: Chilton
mesh_terms: D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001792:Blood Platelets / Q000201:enzymology*; D006801:Humans; D006918:Hydroxyurea / Q000031:analogs & derivatives* / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology*; D007249:Inflammation / Q000503:physiopathology*; D008407:Mast Cells / Q000201:enzymology*; D009000:Monocytes / Q000201:enzymology*; D009504:Neutrophils / Q000201:enzymology*; D009943:Organophosphorus Compounds / Q000494:pharmacology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007093:Imidazoles; D009943:Organophosphorus Compounds; C093303:SK&F 98625; D000217:Acyltransferases; C039766:arachidonyl transacylase; C063449:zileuton; D006918:Hydroxyurea