Imaging techniques in the diabetic foot.
Osteomyelitis underlies the majority of diabetic foot ulcers, and it is usually not detected clinically. Leukocyte scanning with indium oxyquinoline has greater sensitivity than radiographs, bone scans, and MR imaging in diagnosing osteomyelitis in diabetic foot ulcers. All ulcers that expose bone, and perhaps moderately deep ulcers as well, should be treated for osteomyelitis because of the high prevalence of this infection (100% and 82%, respectively). Osteomyelitis should be evaluated for in shallow ulcers by radiographs, followed by leukocyte scans if the former tests are negative. Bone biopsies should be performed if possible because cultures may guide antibiotic treatment.
Newman
L G
LG
Division of Endocrinology and Metabolism, Mount Sinai Medical Center, New York, New York, USA.
D000671:Amputation, Surgical; D001706:Biopsy; D001842:Bone and Bones / Q000473:pathology; D003131:Combined Modality Therapy; D017719:Diabetic Foot / Q000175:diagnosis* / Q000628:therapy; D003952:Diagnostic Imaging; D005500:Follow-Up Studies; D016523:Foot Ulcer / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D010019:Osteomyelitis / Q000175:diagnosis* / Q000628:therapy