Local therapy for mucocutaneous Kaposi's sarcoma in patients with acquired immunodeficiency syndrome.
BACKGROUND
Kaposi's sarcoma (KS) accounts for significant morbidity in AIDS patients. Lessons are often numerous, disfiguring, painful, and may interfere with function. Although generalized therapy is available, local treatment is often more desirable.


OBJECTIVE
To summarize the available data on local therapy for KS.


METHODS
Literature was searched using Medline.


RESULTS
Excision, laser destruction, cryotherapy, intralesional chemotherapy, immunotherapy, and radiation therapy were compared for success rate, cost, and convenience.


CONCLUSIONS
Intralesional therapy, cryotherapy, and radiation all have substantial advantages over excision or laser surgery. Choice of the appropriate modality varies with different sites and patients.
Webster
G F
GF
Department of Dermatology, Jefferson Medical College, Philadelphia, Pennsylvania 19107-5102, USA.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D006801:Humans; D009092:Mucous Membrane; D012514:Sarcoma, Kaposi / Q000150:complications / Q000628:therapy*; D012878:Skin Neoplasms / Q000150:complications / Q000628:therapy*