title: Change in the epidemiology of Reiter's syndrome (reactive arthritis) in the post-AIDS era? An analysis of cases appearing in the Greek Army.
abstract: OBJECTIVE
  During the last 5 years we observed a significant decrease in the incidence of newly established cases of Reiter's syndrome (reactive arthritis) in Greek Army personnel. Our study was initiated to validate this observation and to evaluate a possible change in the prevalence of Reiter's syndrome (RS) associated infections.
  
  
  METHODS
  The case records of patients with reactive arthritis (ReA) admitted during the periods 1980-83 and 1989-92 at a large Army Hospital were studied retrospectively and the cases of RS were reviewed. In addition, the prevalence of cases with urethritis and dysentery that presented to the hospital in the same periods was studied in retrospect, as these infections are known to participate in the etiopathogenesis of RS.
  
  
  RESULTS
  A significant decrease in the overall incidence of the randomly presented RS cases during the second 4 year period was detected (27 versus 4 cases, p < 0.0001, chi 2 test). A similar significant decrease in the number of cases with gonococcal and nongonococcal urethritis was observed while the prevalence of dysentery was not significantly altered during the defined intervals.
  
  
  CONCLUSIONS
  We suggest that the anti-AIDS campaign which began after the years 1984-85 is the principal cause of the observed change of epidemiology of RS cases appearing in the Greek Army.
authors.affiliation: Department of Rheumatology, 401 General Army Hospital of Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Iliopoulos
authors.forename: D
authors.initials: D
authors.lastname: Karras
authors.forename: D
authors.initials: D
authors.lastname: Ioakimidis
authors.forename: A
authors.initials: A
authors.lastname: Arvanitis
authors.forename: N
authors.initials: N
authors.lastname: Tsamis
authors.forename: I
authors.initials: I
authors.lastname: Iakovou
authors.forename: I
authors.initials: I
authors.lastname: Anagnostopoulos
authors.forename: N
authors.initials: N
authors.lastname: Giannikos
mesh_terms: D000328:Adult; D016918:Arthritis, Reactive / Q000453:epidemiology*; D006115:Greece; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D008889:Military Personnel; D015995:Prevalence; D000091402:Prohibitins; D012189:Retrospective Studies