Detection of interleukin-6 and prostaglandin E2 in bronchoalveolar lavage fluids of pigs experimentally infected with Mycoplasma hyponeumoniae.
In this study, interleukin-6 (IL-6) and prostaglandin E2 (PGE2) were detected in the bronchoalveolar lavage fluids (BALF) from pigs experimentally infected with Mycoplasma hyopneumoniae. IL-6 was detected at 2 weeks post-inoculation (PI), and significantly increased levels of PGE2 were observed at 4 weeks PI. In the BALF collected from infected pigs at 4 weeks PI, the levels of IL-6 increased significantly in the pigs with pneumonic lesions. However, increased levels of PGE2 were observed in all the infected pigs.
Asai
T
T
Zen-noh Institute of Animal Health, Chiba, Japan.
Okada
M
M
Ono
M
M
Mori
Y
Y
Yokomizo
Y
Y
Sato
S
S
D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry / Q000276:immunology*; D015232:Dinoprostone / Q000032:analysis*; D015850:Interleukin-6 / Q000032:analysis*; D009177:Mycoplasma pneumoniae / Q000276:immunology; D045729:Pneumonia of Swine, Mycoplasmal / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology* / Q000382:microbiology
D015850:Interleukin-6; D015232:Dinoprostone