Rapid, sensitive, and noninvasive sampling technique for determination of chloroform in alveolar breath.
A sampling technique for the determination of chloroform in alveolar breath is presented. Subjects exhale in a homemade device for collection of the alveolar fraction. The collected sample is transferred to a partially evacuated headspace vial and subsequently analyzed by capillary gas chromatography using electron-capture detection. Concentrations greater than 50 micrograms/m3 can readily be detected. Good correlation observed between chloroform levels in alveolar breath and plasma validates the sampling technique.
LeBlanc
A
A
Le Centre de Toxicologie du Québec, Sainte-Foy, Canada.
Lévesque
B
B
Allaire
S
S
D001944:Breath Tests; D002725:Chloroform / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D002849:Chromatography, Gas; D006801:Humans; D011650:Pulmonary Alveoli / Q000378:metabolism*; D013550:Swimming; D014874:Water Pollutants, Chemical
D014874:Water Pollutants, Chemical; D002725:Chloroform