[Dyslipidemia and reduced fibrinolysis in a child with hemolytic-uremic syndrome].
Many pathogenetic factors may enhance coagulation process and induce thrombosis. The Authors report a case of hemolytic-uremic syndrome, with marked evidence of macroscopic kidney thrombotic involvement, in which an important dyslipidemia (hypertriglyceridemia and hypercholesterolemia) was detected during the phase of clinical improvement. These findings, and the contemporary marked reduction of fibrinolytic activity, seem to be relevant pathogenetic factors in this case. The treatment with polyunsaturated fatty acids Omega 3 may have been helpful in modifying these serum abnormalities and maybe could have brought to the clinical improvement.
Cernecca
F
F
Laboratorio di Patologia dell'Emostasi, I.R.C.C.S. Burlo Garofolo di Trieste, Italia.
Peratoner
L
L
Simeone
R
R
Barbi
E
E
Cattin
L
L
D001778:Blood Coagulation Disorders / Q000150:complications*; D001780:Blood Coagulation Tests; D002675:Child, Preschool; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications* / Q000188:drug therapy; D015228:Hypertriglyceridemia / Q000150:complications* / Q000188:drug therapy; D007668:Kidney / Q000000981:diagnostic imaging; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
D015525:Fatty Acids, Omega-3
Dislipidemia e ridotta fibrinolisi in un bambino con sindrome emolitico-uremica.