title: Helicobacter pylori clearance and eradication with triple therapy in duodenal ulcer patients.
abstract: Triple therapy was given to 49 chronic helicobacter pylori positive chronic duodenal ulcer cases to see its efficacy in H. pylori clearance, eradication and ulcer healing. H. pylori clearance and eradication rates at week 5 and 8 were 87.8% and 81.5% while ulcer healing rates 68.2% and 81.5% respectively. Seven (18%) cases failed to clear H. pylori and were classified as non-responders. Histologically 60% showed post-treatment regression of gastritis. Tolerance to drugs was excellent with a good compliance rate.
authors.affiliation: PMRC Research Centre, Jinnah Postgraduate Medical Centre, Ziauddin Hospital, Karachi.
authors.forename: H
authors.initials: H
authors.lastname: Qureshi
authors.forename: W
authors.initials: W
authors.lastname: Ahmed
authors.forename: S
authors.initials: S
authors.lastname: Syed
authors.forename: T Z
authors.initials: TZ
authors.lastname: Lodi
authors.forename: S J
authors.initials: SJ
authors.lastname: Zuberi
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D005500:Follow-Up Studies; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009942:Organometallic Compounds / Q000627:therapeutic use
chemical_list: D009942:Organometallic Compounds; D008795:Metronidazole; D000658:Amoxicillin; C002791:bismuth tripotassium dicitrate