Water maze performance and hippocampal weight of prenatally stressed rats.
Prenatally stressed rats were tested for water maze performance with the water temperature kept at 18 degrees C (low stress) or cooled down to 12 degrees C (high stress). When the platform had been removed from the pool and the water was kept at 12 degrees C, prenatally stressed males--but not females--spent more time searching for the platform in the correct quadrant of the pool than their controls. Prenatal stress reduced hippocampal weight in both sexes.
Szuran
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T
Department of Animal Science, Swiss Federal Institute of Technology, Zürich.
Zimmermann
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E
Welzl
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H
D000818:Animals; D005260:Female; D006624:Hippocampus / Q000254:growth & development*; D007103:Immobilization; D008297:Male; D018782:Maze Learning / Q000502:physiology*; D009929:Organ Size / Q000502:physiology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar; D012727:Sex Characteristics; D013315:Stress, Psychological / Q000503:physiopathology*