title: [The development of serum alkaline phosphatase and gamma-glutamyl transpeptidase in early stages of primary biliary cirrhosis].
abstract: We carried out a retrospective study for the development of biochemical abnormalities in nine patients with early stages of primary biliary cirrhosis (PBC). All patients had elevated serum alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (gamma-GTP) levels when the diagnosis of PBC was obtained. In all cases, serum gamma-GTP levels initially increased, followed by the elevation of ALP. In the routine laboratory tests gamma-GTP is more sensitive than ALP for the screening for early PBC.
authors.affiliation: Department of Internal Medicine III, Asahikawa Medical College.
authors.forename: M
authors.initials: M
authors.lastname: Ohhira
authors.forename: M
authors.initials: M
authors.lastname: Ohhira
authors.forename: A
authors.initials: A
authors.lastname: Matsumoto
authors.forename: H
authors.initials: H
authors.lastname: Ohta
authors.forename: K
authors.initials: K
authors.lastname: Okuno
authors.forename: M
authors.initials: M
authors.lastname: Okamoto
authors.forename: N
authors.initials: N
authors.lastname: Taya
authors.forename: M
authors.initials: M
authors.lastname: Namiki
mesh_terms: D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase