title: Rapid antibody test for fragile X syndrome.
abstract: Fragile X syndrome is the most common known cause of inherited mental retardation. Identification of patients and carriers of fragile X syndrome is usually done with a DNA test system but we have developed a rapid antibody to identify fragile X patients. This non-invasive test requires only 1 or 2 drops of blood and can be used for screening large groups of mentally retarded people and neonates for fragile X syndrome.
authors.affiliation: Department of Clinical Genetics, Erasmus University, Rotterdam, Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Willemsen
authors.forename: S
authors.initials: S
authors.lastname: Mohkamsing
authors.forename: B
authors.initials: B
authors.lastname: de Vries
authors.forename: D
authors.initials: D
authors.lastname: Devys
authors.forename: A
authors.initials: A
authors.lastname: van den Ouweland
authors.forename: J L
authors.initials: JL
authors.lastname: Mandel
authors.forename: H
authors.initials: H
authors.lastname: Galjaard
authors.forename: B
authors.initials: B
authors.lastname: Oostra
mesh_terms: D000911:Antibodies, Monoclonal; D004247:DNA / Q000235:genetics; D005260:Female; D051860:Fragile X Messenger Ribonucleoprotein 1; D005600:Fragile X Syndrome / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D006580:Genetic Carrier Screening; D006579:Heterozygote; D006801:Humans; D008297:Male; D009419:Nerve Tissue Proteins / Q000097:blood; D016601:RNA-Binding Proteins / Q000097:blood
chemical_list: D000911:Antibodies, Monoclonal; D004247:DNA; D051860:Fragile X Messenger Ribonucleoprotein 1; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins; C497683:FMR1 protein, human