title: Treatment of respiratory failure in an infant with bronchopulmonary dysplasia infected with respiratory syncytial virus using inhaled nitric oxide and high frequency ventilation.
abstract: A 2-month-old, former 28-week premature infant with bronchopulmonary dysplasia infected with respiratory syncytial virus was treated with nitric oxide and high frequency oscillatory ventilation after conventional therapy failed. Nitric oxide and high frequency oscillatory ventilation rapidly improved oxygenation allowing recovery without the need for extracorporeal membrane oxygenation. This treatment regimen should be considered as an option in high-risk infants with respiratory syncytial virus infection who meet extracorporeal membrane oxygenation criteria.
authors.affiliation: Department of Pediatrics and Anesthesia, University of Iowa, Iowa City, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: Thompson
authors.forename: J N
authors.initials: JN
authors.lastname: Bates
authors.forename: J M
authors.initials: JM
authors.lastname: Klein
mesh_terms: D000280:Administration, Inhalation; D001997:Bronchopulmonary Dysplasia / Q000150:complications*; D003131:Combined Modality Therapy; D005260:Female; D006612:High-Frequency Ventilation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009569:Nitric Oxide / Q000008:administration & dosage / Q000627:therapeutic use*; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications*
chemical_list: D009569:Nitric Oxide