title: Contaminated wounds: the effect of initial management on outcome.
abstract: Delayed primary closure has been advocated as the optimal method of management in the presence of wound contamination. The present study was performed to determine whether surgeons have accepted this standard. A total of 918 surgical wounds were evaluated and classified according to the level of contamination and type of wound management used. We found that 150 patients had a Class III or Class IV contaminated wound; however, only 21 per cent were treated with delayed primary closure. The 118 patients treated with primary closure and antibiotics had an aggregate wound infection rate of 27 per cent (Class III-29%; Class IV-24%). Only one (3%) of the wounds managed by delayed primary closure developed an infection. If infection did not occur, there was no difference in the length of stay between patients managed with primary closure and delayed primary closure. However, there was a significantly longer length of stay in the primary closure group if infection occurred. Benefit risk analysis of the patients with contaminated wounds confirmed that in this clinical setting, delayed primary closure remains the optimal method of management for the wound.
authors.affiliation: Department of Surgery, Washington Hospital Center, Washington, D.C. 20010-2975, USA.
authors.forename: R P
authors.initials: RP
authors.lastname: Smilanich
authors.forename: I
authors.initials: I
authors.lastname: Bonnet
authors.forename: J R
authors.initials: JR
authors.lastname: Kirkpatrick
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000209:etiology; D003646:Debridement; D062109:Dermatologic Surgical Procedures; D004322:Drainage; D004754:Enterobacter; D004756:Enterobacteriaceae Infections; D004927:Escherichia coli Infections; D005208:Fasciitis / Q000209:etiology; D000071938:Fasciotomy; D006801:Humans; D007902:Length of Stay; D009336:Necrosis; D012086:Reoperation; D012189:Retrospective Studies; D013492:Suppuration; D013530:Surgical Wound Infection / Q000145:classification / Q000517:prevention & control* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents