title: [Sleep and addiction].
abstract: Sleep disorders and depressive symptoms are concomitant features in patients with addictive disorders. In this study, patients with addiction (alcohol and opioid, resp.) and with major depression (DSM-III-R) were examined with a sleep EEG and compared to age-matched controls. An age-dependent decrease of total sleep time and slow-wave sleep (SWS) was demonstrated. Sober patients with alcohol dependency showed a decrease of SWS, whereas patients with opioid dependency substituted with methadone showed a disorder of REM sleep (REM suppression). Depressive patients revealed a disturbance of sleep continuity and REM sleep (increased REM sleep). The neurobiological differentiation by sleep EEG is of interest for research and clinical practice.
authors.affiliation: Psychiatrische Universitätsklinik, Depressionsforschungsabteilung-Schlafmedizin, Basel.
authors.forename: M
authors.initials: M
authors.lastname: Hatzinger
authors.forename: R
authors.initials: R
authors.lastname: Kocher
authors.forename: U
authors.initials: U
authors.lastname: Hemmeter
authors.forename: D
authors.initials: D
authors.lastname: Ladewig
authors.forename: E
authors.initials: E
authors.lastname: Holsboer-Trachsler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012893:Sleep Wake Disorders / Q000150:complications* / Q000503:physiopathology; D012895:Sleep, REM / Q000502:physiology; D019966:Substance-Related Disorders / Q000150:complications* / Q000503:physiopathology
vernacular_title: Schlaf und Sucht.