title: Adenosine kinase-deficient mutant of Saccharomyces cerevisiae.
abstract: A cordycepin-resistant mutant strain of Saccharomyces cerevisiae (CD-R2) was found to be deficient in adenosine kinase. This mutant accumulated S-adenosylhomocysteine during growth in the presence of exogenous adenosine and it grew in a pseudohyphal manner in the presence of this nucleotide.
authors.affiliation: Department of Biochemistry, Kyoto Prefectural University of Medicine, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Iwashima
authors.forename: M
authors.initials: M
authors.lastname: Ogata
authors.forename: K
authors.initials: K
authors.lastname: Nosaka
authors.forename: H
authors.initials: H
authors.lastname: Nishimura
authors.forename: T
authors.initials: T
authors.lastname: Hasegawa
mesh_terms: D000241:Adenosine / Q000378:metabolism; D000248:Adenosine Kinase / Q000235:genetics*; D001711:Biotransformation; D002455:Cell Division / Q000187:drug effects; D003839:Deoxyadenosines / Q000493:pharmacokinetics / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D009154:Mutation; D012435:S-Adenosylhomocysteine / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics*; D013831:Thiamine / Q000494:pharmacology
chemical_list: D003839:Deoxyadenosines; D012435:S-Adenosylhomocysteine; D000248:Adenosine Kinase; C058120:cordycepin; D000241:Adenosine; D013831:Thiamine