Cloning of a canine cDNA homologous to the human transforming growth factor-beta 1-encoding gene.
A 1369-bp cDNA that encodes a homolog of the human transforming growth factor-beta 1 (TGF-beta 1) has been isolated from canine endothelial cells using a combination of PCR and traditional plaque-screening methods. The deduced 390-amino-acid sequence of the canine TGF-beta 1 precursor has 91-94% identity to those deduced from the previously described human and mouse TGF-beta 1 clones.
Manning
A M
AM
Upjohn Laboratories, Kalamazoo, MI 49001, USA.
Auchampach
J A
JA
Drong
R F
RF
Slightom
J L
JL
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D004285:Dogs; D006801:Humans; D008969:Molecular Sequence Data; D017385:Sequence Homology; D016212:Transforming Growth Factor beta / Q000235:genetics*
D018076:DNA, Complementary; D016212:Transforming Growth Factor beta