Structure of the NF-kappa B transcription factor: a holistic interaction with DNA.
An unexpected mode of binding to DNA is revealed in two crystal structures of a transcription factor that is essential for many signalling pathways in eukaryotic cells.
Kuriyan
J
J
Howard Hughes Medical Institute, Rockefeller University, New York, NY 10021, USA.
Thanos
D
D
D000818:Animals; D001483:Base Sequence; D003196:Computer Graphics; D004247:DNA / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000737:chemistry* / Q000378:metabolism*; D011487:Protein Conformation; D015398:Signal Transduction / Q000502:physiology; D014158:Transcription, Genetic
D016328:NF-kappa B; D004247:DNA