[A study of the simultaneous acquisition of dual energy SPECT with 99mTc and 123I: evaluation of optimal window setting with myocardial phantom].
To examine crosstalks (CRs) between 99mTc-methoxyisobutyl isonitrile (MIBI) and beta-methyl-p-(123I)iodophenyl-pentadecanoic acid (BMIPP), myocardial phantom studies of simultaneous acquisition were performed with three window widths and four energies where the window located. CRS in 99mTc window were less than 10.5% regardless of the window settings. CRs in 123I window were ranging from 17.0% to 8.6% depending on the window setting. There were significant correlations between the isotope concentration and counts of 99mTc and 123I, respectively (r = 0.98, p < 0.0001). We concluded that the optimal window setting of 99mTc-MIBI and 123I-BMIPP (10% width, 140 keV center 99mTc window and 10% width, 164 keV center 123I window) yields good quality images in dual isotope SPECT.
Mizumura
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Department of Radiology, Nippon Medical School.
Kumita
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Kumazaki
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D000368:Aged; D003652:Decanoic Acids; D005227:Fatty Acids; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008955:Models, Cardiovascular; D008961:Models, Structural; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
D003652:Decanoic Acids; D005227:Fatty Acids; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; C049338:iodofiltic acid; D017256:Technetium Tc 99m Sestamibi