Synthesis of some new 1,3,4-oxadiazoline-2 thione derivatives with antibacterial activity.
Three new 5-[(1-benzoylamino)styren-1-yl]-1,3,4-oxadiazoline-2- thiones and nine of their Mannich bases with some primary and secondary amines and three N-hydroxymethyl derivatives are synthesized. Some of the new derivatives were active against the bacteria Escherichia coli.
Mashaly
M
M
Department of Chemistry, Faculty of Science (Damietta), Mansoura University, Egypt.
Khodeir
M N
MN
Hanna
M
M
El-Shafei
H
H
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010069:Oxadiazoles