title: [Syncumar-induced necrosis following heparin-induced thrombocytopenia and thrombosis].
abstract: The authors describe the combined occurrence of heparin-induced thrombocytopenia and cumarin-induced skin necrosis, a rare condition that has not yet been reported in Hungary. The 69-year-old woman had received prophylactic heparin treatment prior to total hip arthroplasty. The first complication that the anticoagulant therapy brought about was serious thrombocytopenia paradoxically associated not with bleeding but with deep vein thrombosis. The latter necessitated coumarin therapy which resulted in severe skin necrosis.
authors.affiliation: Debreceni Orvostudományi Egyetem II. Belgyógyászati Klinika.
authors.forename: E
authors.initials: E
authors.lastname: Pósán
authors.forename: S
authors.initials: S
authors.lastname: Adi
authors.forename: G
authors.initials: G
authors.lastname: Szücs
authors.forename: J
authors.initials: J
authors.lastname: Rigó
authors.forename: Z
authors.initials: Z
authors.lastname: Boda
mesh_terms: D000074:Acenocoumarol / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006622:Hip Prosthesis; D006801:Humans; D009336:Necrosis / Q000139:chemically induced; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000150:complications; D013924:Thrombophlebitis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D006493:Heparin; D000074:Acenocoumarol
vernacular_title: Heparin indukálta thrombocytopeniát és thrombosist követö syncumar-necrosis esete.