Salt stress is an environmental signal affecting degradative enzyme synthesis in Bacillus subtilis.
Growth under conditions of salt stress has important effects on the synthesis of degradative enzymes in Bacillus subtilis. Salt stress strongly stimulates the expression of sacB, encoding levansucrase (about ninefold), and downregulates the expression of aprE, encoding alkaline protease (about sixfold). It is suggested that the DegS-DegU two-component system is involved in sensing salt stress. Moreover, it has been shown that the level of sacB expression strongly depends on the growth conditions; its expression level is about eightfold higher in cells grown on agar plates than in cells grown in liquid medium.
Kunst
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F
URA 1300, Centre National de la Recherche Scientifique, Département des Biotechnologies, Institut Pasteur, Paris, France.
Rapoport
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G
D000220:Adaptation, Biological; D001412:Bacillus subtilis / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics / Q000502:physiology; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006602:Hexosyltransferases / Q000096:biosynthesis; D026901:Membrane Transport Proteins; D008957:Models, Genetic; D012492:Salts / Q000494:pharmacology*; D012697:Serine Endopeptidases / Q000096:biosynthesis; D015398:Signal Transduction / Q000502:physiology*
C088074:AprE protein, Bacteria; D001426:Bacterial Proteins; C066496:DegS protein, Bacteria; C066497:DegU protein, Bacteria; D026901:Membrane Transport Proteins; D012492:Salts; D006602:Hexosyltransferases; C021513:levansucrase; D012697:Serine Endopeptidases; C032923:microbial serine proteinases