[Drug sensitivity of bronchial small cell cancers transplanted to nude mice. Expression of the mdr1 gene and correlation with clinical practice. Effects of antagonists].
Poupon
M F
MF
URA 620 CNRS, Institut Curie, Paris, France.
Arvelo
F
F
Bourgeois
Y
Y
Jacrot
M
M
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors / Q000235:genetics*; D000818:Animals; D001984:Bronchial Neoplasms / Q000188:drug therapy*; D018288:Carcinoma, Small Cell / Q000188:drug therapy*; D018432:Drug Resistance, Multiple; D015870:Gene Expression; D005982:Glutathione Transferase / Q000235:genetics; D006801:Humans; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D011379:Prognosis; D012333:RNA, Messenger / Q000235:genetics; D012334:RNA, Neoplasm / Q000235:genetics; D014700:Verapamil / Q000494:pharmacology
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D014700:Verapamil; D005982:Glutathione Transferase
Chimiosensibilité des cancers bronchiques à petites cellules greffés sur souris nude. Expression due gène mdr1 et corrélation avec la clinique. Intérêts des agents de réversion.