title: Normal pressure hydrocephalus associated with rheumatoid arthritis responding to prednisone.
abstract: We describe 2 patients with longstanding rheumatoid arthritis (RA) complicated by normal pressure hydrocephalus. After treatment with prednisone, both patients improved remarkably with respect to mental status, urinary control, and gait. We suggest that normal pressure hydrocephalus may occur as an extraarticular manifestation of RA, and studies are warranted to confirm a beneficial response to prednisone.
authors.affiliation: Department of Rheumatology, Dr. Daniel den Hoed Clinic, Rotterdam, The Netherlands.
authors.forename: H M
authors.initials: HM
authors.lastname: Markusse
authors.forename: P H
authors.initials: PH
authors.lastname: Hilkens
authors.forename: M J
authors.initials: MJ
authors.lastname: van den Bent
authors.forename: C J
authors.initials: CJ
authors.lastname: Vecht
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D005684:Gait; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000209:etiology* / Q000503:physiopathology; D008603:Mental Health; D011241:Prednisone / Q000627:therapeutic use*; D012016:Reference Values; D014554:Urination
chemical_list: D011241:Prednisone