[Mechanism of changes in coagulation after electric burns in rabbits].
The changes in local lesion after high-voltage electric burns ares dependent on many factors. One of the important factors is the change in coagulation. In this paper, a high-voltage electrical burn model was reproduced in rabbits for the purpose of investigating the coagulation mechanism. It was found that AT-III and PC showed elevation and declination, respectively, at 6h and 12h postburn. PAI:A and t-PA:A also showed obvious changes, while FDP showed continuous elevation at 6h up to 5d postburn. The findings probable provided the explanation of the occurrence of thrombosis at 6h to 12h postburn, and the second episode of thrombosis on the 5th day.
Chen
G
G
Burn Unit, Shanghai DianLi Hospital.
Wu
Y
Y
Xu
X
X
D000818:Animals; D000990:Antithrombin III / Q000378:metabolism; D001778:Blood Coagulation Disorders / Q000209:etiology*; D002058:Burns, Electric / Q000097:blood* / Q000150:complications; D005260:Female; D008297:Male; D015849:Plasminogen Inactivators / Q000378:metabolism; D011486:Protein C / Q000378:metabolism; D011817:Rabbits; D010959:Tissue Plasminogen Activator / Q000378:metabolism
D015849:Plasminogen Inactivators; D011486:Protein C; D000990:Antithrombin III; D010959:Tissue Plasminogen Activator