title: [Lactate dehydrogenase activity in the diagnosis of retinoblastoma].
abstract: The authors examined the lactic dehydrogenase activity and that of its isoenzymes in a group of 22 orbit with a confirmed diagnosis of retinoblastoma. They investigated and evaluate total LDH in the vitreous humour and blood serum and the ration of isoenzymes LDH 5 to LDH 1 in the same media. The assembled results confirmed that in eyes with retinoblastomas a significant pathological rise not only of the total LDH takes place but the response of isoenzymes is even more sensitive. The examination is therefore a qualitative asset to the clinical diagnosis of retinoblastoma.
authors.affiliation: Dĕtská ocní klinika LF MU, Brno.
authors.forename: J
authors.initials: J
authors.lastname: Rehůrek
authors.forename: J
authors.initials: J
authors.lastname: Snopková
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D004796:Clinical Enzyme Tests; D005134:Eye Neoplasms / Q000175:diagnosis*; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D012175:Retinoblastoma / Q000175:diagnosis*
chemical_list: D014408:Biomarkers, Tumor; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
vernacular_title: Aktivita laktikodehydrogenázy v diagnostice retinoblastomu.