title: Increased technetium-99m-HMPAO uptake in grade II astrocytoma.
abstract: Most brain tumors show decreased uptake of blood flow tracers in brain SPECT imaging and in some cases meningiomas show increased uptake, mainly associated with high regional blood flow values. A reason for regionally increased tracer uptake is partial epilepsy when a tracer is injected during the ictal phase. We present a case of a histologically proven Grade II astrocytoma in the mesial part of the left temporal lobe that caused complex partial seizures. After tracer injection during a phase without signs of clinical seizure, markedly increased uptake of 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) occurred, although the tumor was partially calcified.
authors.affiliation: Department of Nuclear Medicine, University of Bonn, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Grünwald
authors.forename: C
authors.initials: C
authors.lastname: Menzel
authors.forename: T
authors.initials: T
authors.lastname: Pietsch
authors.forename: L
authors.initials: L
authors.lastname: Pavics
authors.forename: A
authors.initials: A
authors.lastname: Hufnagel
authors.forename: H J
authors.initials: HJ
authors.lastname: Biersack
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D017029:Epilepsy, Complex Partial / Q000209:etiology; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D013702:Temporal Lobe / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime