title: A microdissection library of the rat renal carcinoma gene region.
abstract: Predisposition to hereditary renal carcinoma in the Eker rat involves a mutation of a putative tumor suppressor gene within chromosome band 10q12. We describe the identification of three unique polymorphic sequences in the vicinity of this locus following the microdissection, construction and characterization of a region-specific DNA library for rat chromosome band 10q12.
authors.affiliation: Division of Medical Sciences, Fox Chase Cancer Center, Philadelphia, PA, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Bell
authors.forename: R S
authors.initials: RS
authors.lastname: Yeung
authors.forename: S K
authors.initials: SK
authors.lastname: Bohlander
authors.forename: J Q
authors.initials: JQ
authors.lastname: Cheng
authors.forename: F
authors.initials: F
authors.lastname: Jin
authors.forename: J R
authors.initials: JR
authors.lastname: Testa
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D002292:Carcinoma, Renal Cell / Q000235:genetics*; D002874:Chromosome Mapping; D004210:Dissection / Q000379:methods; D015723:Gene Library; D017404:In Situ Hybridization, Fluorescence; D007680:Kidney Neoplasms / Q000235:genetics*; D008846:Micromanipulation; D016133:Polymerase Chain Reaction; D051381:Rats