[Detection of cervical human papillomavirus infection from women with external genital condyloma acuminata].
Cervical biopsy specimens were taken from 36 women with external genital condyloma acuminata in order to diagnose a concomitant cervical human papillomavirus (HPV) infection. Positive HPV infection rate of cervix was 16% (6/36) by routine visual examination, 69% (25/36) by colposcopy and 56% (18/32) by pathology. Among those patients 31% (10/32) have grade I-II cervical intraepithelial neoplasia (CIN) according to pathology. In 8 cases, both vulva and cervical specimens were examined by Southern blot, dot blot and polymerase chain reaction (PCR) technique. HPV DNA positive was detected in 7 of 8 cervical specimens. It is concluded cervical HPV infection was rather common in women with external genital condyloma acuminata and it is valuable to examine cervical HPV infection by colposcopy and biopsy to detect the concomitant CIN.
Song
X H
XH
Chao Yang Hospital, Beijing.
Yu
X M
XM
Weng
L J
LJ
D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000821:virology; D003218:Condylomata Acuminata / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections; D011446:Prospective Studies; D014412:Tumor Virus Infections; D002583:Uterine Cervical Neoplasms / Q000821:virology; D002575:Uterine Cervicitis / Q000821:virology*; D014845:Vulvar Diseases / Q000821:virology*; D002578:Uterine Cervical Dysplasia / Q000821:virology
D004279:DNA, Viral