title: [Isolated lung transplantation--evaluation of patients and initial results].
abstract: Between November 1992 and May 1994 we performed 10 single and 5 double lung transplants in patients with end-stage lung diseases due to lymphangioleiomyomatosis (4), cystic fibrosis (3), pulmonary hypertension (3), pulmonary fibrosis (3) and chronic obstructive lung disease (2). In the 13 patients (87%) surviving for median 245 (19-567) days, FEV1 improved from median 640 ml to 1410 ml and the 12-minute walk distance from median 315 to 1100 meters. 10 patients (77%) enjoy a good or even excellent quality of life. 2 patients died 11 and 62 days postoperatively, due to multi-organ failure and invasive pulmonary aspergillosis respectively. The main postoperative problems are fungal and cytomegalovirus infections and chronic rejection in the form of bronchiolitis obliterans. In Switzerland as elsewhere, lung transplantation has become an established modality for the management of end-stage diseases of the lung and pulmonary circulation.
authors.affiliation: Departement Innere Medizin, Universitätsspital Zürich.
authors.forename: R
authors.initials: R
authors.lastname: Speich
authors.forename: A
authors.initials: A
authors.lastname: Böhler
authors.forename: A
authors.initials: A
authors.lastname: Zollinger
authors.forename: R
authors.initials: R
authors.lastname: Stocker
authors.forename: P
authors.initials: P
authors.lastname: Vogt
authors.forename: T
authors.initials: T
authors.lastname: Carrel
authors.forename: T
authors.initials: T
authors.lastname: Lang
authors.forename: R
authors.initials: R
authors.lastname: Schmid
authors.forename: S
authors.initials: S
authors.lastname: Stöhr
authors.forename: P R
authors.initials: PR
authors.lastname: Vogt
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D000075202:Contraindications; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007902:Length of Stay; D008171:Lung Diseases / Q000601:surgery*; D016040:Lung Transplantation / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011788:Quality of Life; D012129:Respiratory Function Tests; D016019:Survival Analysis; D016896:Treatment Outcome
vernacular_title: Die isolierte Lungentransplantation--Evaluation von Patienten und erste Resultate.