[Mixed cryoglobulinemia associated with hepatitis C virus].
We report six cases of essential mixed cryoglobulinemia associated with chronic liver disease and positive HCV markers, who showed several acute symptoms of vasculitis, arthralgias, neuropathy and glomerulonephritis. The presence in the serum and cryoprecipitates of anti HCV antibodies detected by the second-generation ELISA (ELISA 2) and the of HCV RNA by PCR in the serum in all six cases, suggest an important role for this virus in the pathogenesis of mixed cryoglobulinemia.
De Diego Lorenzo
A
A
Servicio de Aparato Digestivo, Hospital General Universitario, Gregorio Marañón, Madrid.
Bañares Cañizares
R
R
González-Asanza
C
C
Pérez Roldán
F
F
Casado Martín
M
M
Hernández-Albújar
A
A
Cos Arregui
E
E
Clemente Ricote
G
G
D000328:Adult; D003449:Cryoglobulinemia / Q000150:complications* / Q000821:virology; D005260:Female; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged
Crioglobulinemia mixta asociada al virus de la hepatitis C.