title: Malignancy in Maffucci's syndrome.
abstract: Maffucci's syndrome is characterized by multiple enchondromas and subcutaneous hemangiomas. These tumors typically present in early childhood and may lead to significant skeletal deformities. Malignant transformations are a common feature of this syndrome and have been reported in approximately 30% of reported cases, with chondrosarcomas being the most common.
authors.affiliation: Department of Dermatology, University of Texas-Houston Medical School, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Albregts
authors.forename: R P
authors.initials: RP
authors.lastname: Rapini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology; D002648:Child; D002813:Chondrosarcoma / Q000473:pathology; D004687:Enchondromatosis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D005500:Follow-Up Studies; D006391:Hemangioma / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology