Intense nutritional support in inflammatory bowel disease.
The value of intense nutritional support in inflammatory bowel disease is still debated. Claims have been made that total enteral nutrition is as effective as total parental nutrition. In this review, the use of parenteral and enteral nutritional support as primary therapy in patients with inflammatory bowel disease has been critically evaluated. Most studies have been uncontrolled and nonrandomized with short-term follow-up. The literature does suggest, however, that intense nutritional support may have an adjunctive role to drug therapy in achieving remission in Crohn's disease, especially in corticosteroid-refractory patients. Nutritional support has a lesser role in chronic ulcerative colitis, except for assistance in pre- and postoperative management. The data do not support one variety of nutritional support over another, although enteral support should be used if possible, as it is less costly and potentially less complicated.
Wu
S
S
Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611, USA.
Craig
R M
RM
D005526:Food, Formulated; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000628:therapy*; D018529:Nutritional Support