Extensive personal experience: gonadotroph adenomas.
Our experience with gonadotroph adenomas during the last 20 years has taught us how to recognize them by their size, neurologic symptoms, and inefficient and incomplete secretion of intact gonadotropins and their subunits. Treatment now is primarily by transsphenoidal surgery and secondarily by radiation. Future development of a pharmacologic treatment will likely await more detailed knowledge of their pathogenesis.
Snyder
P J
PJ
Division of Endocrinology, Metabolism and Diabetes, University of Pennsylvania School of Medicine, Philadelphia 19104-6149, USA.
D000236:Adenoma / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000628:therapy; D012658:Sella Turcica