title: [Mechanisms of formation and action of polypeptide bio-regulators-- cytomedins ].
abstract: Possible mechanism of synthesis and effects of polypeptide bioregulative molecules (cytomedines) have been shown. This polypeptide has been obtained from different organs and tissues of animals. Its effects are supposed to be based on the processes of intercellular exchange and the cross-membrane transference of information signals. Synthesis of these molecules is considered as the limited proteolysis of protein structures. The information molecules of this kind will be found both inside and outside the cells. The evolution of regulative polypeptides was shown from the organisms of prebiotic era till contemporary organisms. The possibility of interaction between entigenic--endogenic peptides and regulative peptides is described. A hypothetic scheme of the effect of polypeptide molecules on the cell populations is suggested. Space interactions between proteins and polypeptides on the basis of the recognition codes of aminoacids can be most important factors.
authors.forename: I P
authors.initials: IP
authors.lastname: Kaĭdashev
mesh_terms: D000818:Animals; D002450:Cell Communication; D002462:Cell Membrane / Q000502:physiology*; D005110:Extracellular Space / Q000502:physiology*; D006801:Humans; D007155:Immunologic Factors / Q000502:physiology*; D010455:Peptides / Q000502:physiology*
chemical_list: D007155:Immunologic Factors; D010455:Peptides; C053892:cytomedins
vernacular_title: Mekhanizmy utvorennia ta diĭ polipeptydnykh bioreguliatoriv--tsytomediniv.