title: Neurobehavioral treatment for cocaine-using methadone patients: a preliminary report.
abstract: Preliminary outcome evaluation results are reported for an innovative cocaine abuse treatment model adapted for cocaine-using methadone patients. Sixty-two patients were randomly assigned to six months of high intensity ("neurobehavioral") or lower intensity ("control") therapy for cocaine dependence. Therapy was completed by 49% of neurobehavioral and 53% of control patients. In paired comparisons between intake and six-month follow-up, neurobehavioral patients but not controls showed significant declines in cocaine and other drug use (measured by urinalysis and self-reports), as well as significant improvement in psychological status. The findings suggest that specialized cocaine abuse treatment can benefit methadone patients; intake to the study is continuing.
authors.affiliation: National Development and Research Institutes, Inc., New York, NY 10013, USA.
authors.forename: S
authors.initials: S
authors.lastname: Magura
authors.forename: A
authors.initials: A
authors.lastname: Rosenblum
authors.forename: M
authors.initials: M
authors.lastname: Lovejoy
authors.forename: L
authors.initials: L
authors.lastname: Handelsman
authors.forename: J
authors.initials: J
authors.lastname: Foote
authors.forename: B
authors.initials: B
authors.lastname: Stimmel
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D003042:Cocaine; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009483:Neuropsychological Tests; D010552:Personality Assessment; D013375:Substance Withdrawal Syndrome / Q000534:rehabilitation; D019966:Substance-Related Disorders / Q000534:rehabilitation*; D016896:Treatment Outcome
chemical_list: D003042:Cocaine; D008691:Methadone