title: Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations.
abstract: We studied the effects of closing lacerations with suture or cyanoacrylate tissue adhesive on staphylococcal counts in inoculated guinea pig lacerations. Wounds closed with adhesive alone had lower counts than wounds containing suture material (P < 0.05). The results of a time-kill study were consistent with a bacteriostatic adhesive effect of the adhesive against Staphylococcus aureus.
authors.affiliation: Department of Emergency Medicine, Georgetown University Hospital, Washington, D.C., USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Howell
authors.forename: K A
authors.initials: KA
authors.lastname: Bresnahan
authors.forename: T O
authors.initials: TO
authors.lastname: Stair
authors.forename: H S
authors.initials: HS
authors.lastname: Dhindsa
authors.forename: B A
authors.initials: BA
authors.lastname: Edwards
mesh_terms: D000818:Animals; D004659:Enbucrilate / Q000031:analogs & derivatives* / Q000494:pharmacology; D006168:Guinea Pigs; D008297:Male; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D013537:Sutures; D014014:Tissue Adhesives / Q000494:pharmacology*; D014946:Wound Infection / Q000382:microbiology*
chemical_list: D014014:Tissue Adhesives; D004659:Enbucrilate