title: Differences in mortality after fracture of hip: the east Anglian audit.
abstract: OBJECTIVE
  To investigate differences between hospitals in clinical management of patients admitted with fractured hip and to relate these to mortality at 90 days.
  
  
  METHODS
  A prospective audit of process and outcome of care based on interviews with patients, abstraction from records with standard proforma, and follow up at three months. Data were analysed with chi 2 test and forward stepwise regression modelling of mortality.
  
  
  METHODS
  All eight hospitals in East Anglia with trauma orthopaedic departments.
  
  
  METHODS
  580 consecutive patients admitted for fracture of neck of femur.
  
  
  METHODS
  Mortality at 90 days.
  
  
  RESULTS
  Patients admitted to each hospital were similar with respect to age, sex, pre-existing illnesses, and activities of daily living before fracture. In all, 560 (97%) were treated surgically, by a range of grades of surgeon. Two hundred and sixty one patients (45%; range between hospitals 10-91%) received pharmaceutical thromboembolic prophylaxis, 502 (93%; 81-99%) perioperative antibiotic prophylaxis. The incidence of fatal pulmonary emboli differed between patients who received and those who did not receive prophylaxis against deep vein thrombosis (P = 0.001). Mortality at 90 days was 18%, differing significantly between hospitals (5-24%). One hospital had significantly better survival than the others (odds ratio 0.14; 95% confidence interval 0.04-0.48; P = 0.0016).
  
  
  CONCLUSIONS
  No single factor or aspect of practice accounted for this protective effect. Lower mortality may be associated with the cumulative effects of several aspects of the organisation of treatment and the management of fracture of the hip, including thromboembolic pharmaceutical prophylaxis, antibiotic prophylaxis, and early mobilisation.
authors.affiliation: Department of Community Medicine, University of Cambridge.
authors.forename: C J
authors.initials: CJ
authors.lastname: Todd
authors.forename: C J
authors.initials: CJ
authors.lastname: Freeman
authors.forename: C
authors.initials: C
authors.lastname: Camilleri-Ferrante
authors.forename: C R
authors.initials: CR
authors.lastname: Palmer
authors.forename: A
authors.initials: A
authors.lastname: Hyder
authors.forename: C E
authors.initials: CE
authors.lastname: Laxton
authors.forename: M J
authors.initials: MJ
authors.lastname: Parker
authors.forename: B V
authors.initials: BV
authors.lastname: Payne
authors.forename: N
authors.initials: N
authors.lastname: Rushton
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D004434:Early Ambulation; D005260:Female; D005265:Femoral Neck Fractures / Q000401:mortality* / Q000601:surgery; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D016015:Logistic Models; D008297:Male; D008485:Medical Audit; D008505:Medical Staff, Hospital; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D015996:Survival Rate; D013923:Thromboembolism / Q000401:mortality / Q000517:prevention & control; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D000925:Anticoagulants