title: A Drosophila male accessory gland protein that is a member of the serpin superfamily of proteinase inhibitors is transferred to females during mating.
abstract: Accessory gland peptide 76A, (Acp76A), belongs to the serpin superfamily of proteins (serine protease inhibitors). Acp76A is a secreted protein synthesized only in the Drosophila melanogaster adult male accessory gland. Accumulation of the protein in males is first detected with polyclonal antibodies at 1 day after eclosion. The level of the protein in virgin males reaches a peak 5-8 days post-eclosion, and remains constant for at least 20 days. Upon mating the amount of Acp76A in males drops dramatically, but recovers by 24 h after mating. Immediately after mating the Acp76A is found in the female uterus. By 6 h after mating the amount of Acp76A detected in females is drastically reduced.
authors.affiliation: Department of Biology, Luther College, Decorah, IA 52101.
authors.forename: S
authors.initials: S
authors.lastname: Coleman
authors.forename: B
authors.initials: B
authors.lastname: Drähn
authors.forename: G
authors.initials: G
authors.lastname: Petersen
authors.forename: J
authors.initials: J
authors.lastname: Stolorov
authors.forename: K
authors.initials: K
authors.lastname: Kraus
mesh_terms: D000818:Animals; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D005260:Female; D005298:Fertility; D005786:Gene Expression Regulation; D006458:Hemolymph / Q000378:metabolism; D036341:Intercellular Signaling Peptides and Proteins; D008297:Male; D010455:Peptides / Q000235:genetics / Q000378:metabolism*; D015843:Serpins / Q000235:genetics / Q000378:metabolism*; D012726:Sexual Behavior, Animal; D015398:Signal Transduction; D013997:Time Factors; D014599:Uterus / Q000378:metabolism
chemical_list: D029721:Drosophila Proteins; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D015843:Serpins; C489177:Acp36DE protein, Drosophila; C056736:SP protein, Drosophila