title: Transfer of six or more embryos improves success rates in patients with repeated in vitro fertilization failures.
abstract: OBJECTIVE
  To examine the results of six or more embryos transferred to patients whose IVF-ET cycles repeatedly met with failure.
  
  
  METHODS
  Prospective clinical evaluation of pregnancy rates and pregnancy outcome.
  
  
  METHODS
  IVF-ET Unit.
  
  
  METHODS
  Seventy-two IVF patients who had failed at least four previous IVF cycles.
  
  
  METHODS
  Forty-one patients (group A) received six or more embryos, and 31 patients (group B) chose to receive five embryos.
  
  
  METHODS
  Per embryo implantation rate, pregnancy rate, multiple pregnancies, and outcome were evaluated.
  
  
  RESULTS
  With the transfer of six or more embryos, the pregnancy rate was significantly higher than with the transfer of five embryos (56% versus 29%, respectively). This was associated with a slight, but insignificant, increase in multiple gestations. No difference in pregnancy outcome was noted among the groups.
  
  
  CONCLUSIONS
  Patients who have had repeated IVF failures may have higher pregnancy rates if six or more embryos are transferred in subsequent cycles.
authors.affiliation: Tel Aviv Sourasky Medical Center, Serlin Maternity Hospital, Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors.forename: F
authors.initials: F
authors.lastname: Azem
authors.forename: Y
authors.initials: Y
authors.lastname: Yaron
authors.forename: A
authors.initials: A
authors.lastname: Amit
authors.forename: I
authors.initials: I
authors.lastname: Yovel
authors.forename: Y
authors.initials: Y
authors.lastname: Barak
authors.forename: M R
authors.initials: MR
authors.lastname: Peyser
authors.forename: M P
authors.initials: MP
authors.lastname: David
authors.forename: J B
authors.initials: JB
authors.lastname: Lessing
mesh_terms: D000328:Adult; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D011446:Prospective Studies