Expression of sialylparagloboside in a case of liposarcoma: aberrant glycosylation in tumors arising in adipose tissues.
Gangliosides of liposarcoma, lipoma and lipids from omental tissues were analyzed. By immunostaining after thin layer chromatography, gangliosides of liposarcoma were identified as GM3, sialylparagloboside and GD3, whereas those of lipoma were GM3 and GD3, and those of fat in omental tissues were GM3, GD1a, GD3 and some unknown ones. Expression of sialylparagloboside is thought to be very rare.
Kubo
Y
Y
Department of First Internal Medicine, Yamaguchi University School of Medicine.
Hamanaka
S
S
Kawashima
I
I
Tai
T
T
Kawamura
S
S
Okita
K
K
D000273:Adipose Tissue / Q000737:chemistry*; D000328:Adult; D000911:Antibodies, Monoclonal; D002855:Chromatography, Thin Layer; D005260:Female; D005732:Gangliosides / Q000032:analysis*; D006031:Glycosylation; D006801:Humans; D007150:Immunohistochemistry; D008067:Lipoma / Q000737:chemistry; D008080:Liposarcoma / Q000737:chemistry* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009852:Omentum / Q000033:anatomy & histology; D012186:Retroperitoneal Neoplasms / Q000737:chemistry* / Q000473:pathology
D000911:Antibodies, Monoclonal; D005732:Gangliosides; C025447:sialogangliosides