[Use of continuous stacking hybridization in sequencing using modified oligonucleotide matrices].
The opportunity of DNA sequencing by hybridization with oligonucleotide matrix (SHOM) with simultaneously use continuous stacking hybridization and gapped-matrices is considered. The analysis of reconstruction efficiency for various combinations matrices and l-oligonucleotides libraries were made. In most cases combine use of continuous stacking hybridization and gapped matrices permits to decrease the number of additional stacking hybridization twice without lost of efficiency.
Lysov
Iu N
IuN
Chernyĭ
A A
AA
Balaev
A A
AA
Gnuchev
F N
FN
Beattie
K L
KL
Mirzabekov
A D
AD
D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides; D017422:Sequence Analysis, DNA; D013698:Templates, Genetic
D009841:Oligonucleotides
Ispol'zovanie gibridizatsii vstyk pri sekvenirovanii s pomoshch'iu modifitsirovannykh oligonukleotidnykh matrits.