title: Shielding design and dose assessment for accelerator based neutron capture therapy.
abstract: Preparations are ongoing to test the viability and usefulness of an accelerator source of epithermal neutrons for ultimate use in a clinical environment. This feasibility study is to be conducted in a shielded room located on the Massachusetts Institute of Technology campus and will not involve patient irradiations. The accelerator production of neutrons is based on the 7Li(p, n)7Be reaction, and a maximum proton beam current of 4 mA at an energy of 2.5 MeV is anticipated. The resultant 3.58 x 10(12) neutrons s-1 have a maximum energy of 800 keV and will be substantially moderated. This paper describes the Monte Carlo methods used to estimate the neutron and photon dose rates in a variety of locations in the vicinity of the accelerator, as well as the shielding configuration required when the device is run at maximum current. Results indicate that the highest absorbed dose rate to which any individual will be exposed is 3 microSv h-1 (0.3 mrem h-1). The highest possible yearly dose is 0.2 microSv (2 x 10(-2) mrem) to the general public or 0.9 mSv (90 mrem) to a radiation worker in close proximity to the accelerator facility. The shielding necessary to achieve these dose levels is also discussed.
authors.affiliation: Department of Physics, Massachusetts Institute of Technology, Cambridge 02139, USA.
authors.forename: W B
authors.initials: WB
authors.lastname: Howard
authors.forename: J C
authors.initials: JC
authors.lastname: Yanch
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D016754:Boron Neutron Capture Therapy / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D004867:Equipment Design; D006801:Humans; D008094:Lithium; D009010:Monte Carlo Method; D016273:Occupational Exposure; D010315:Particle Accelerators; D017785:Photons; D011829:Radiation Dosage; D011835:Radiation Protection / Q000295:instrumentation*
chemical_list: D008094:Lithium