Transcranial magnetic stimulation of the trigeminal nerve: intraoperative study on stimulation characteristics in man.
We studied responses from the masseter and nasalis muscles following magnetic stimulation (magStim) and compared these responses with those obtained by direct electrical stimulation of the trigeminal (NV) and facial (NVII) nerve near the root exit zone during microvascular decompression operations of NVII. We found that (1) magStim threshold to excite the nerve is high for NV and low for NVII; (2) excitation of all motor fibers is impossible for NV, and easy for NVII; (3) optimal coil placement is critical for NV, but not critical for NVII; and (4) between and within subjects, the excitation site is variable on NV, but stable on NVII. We estimated that the anatomical location of magStim to be either within or outside the cerebrospinal fluid for NV, and to be in the labyrinthine segment of the facial canal for NVII. Physical models explain and clinical lesion models support these differences found between NV and NVII.
Schmid
U D
UD
Department of Neurosurgery, Ludwig-Maximilian-University, Klinikum Grosshadern, München, Germany.
Møller
A R
AR
Schmid
J
J
D000328:Adult; D000368:Aged; D004558:Electric Stimulation / Q000379:methods*; D005154:Facial Nerve / Q000601:surgery; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology; D012016:Reference Values; D050781:Transcranial Magnetic Stimulation; D014276:Trigeminal Nerve / Q000503:physiopathology*