Stimulation of sarcolemmal sodium-hydrogen exchange in cardiac myocytes as a mediator of the positive inotropic action of alpha 1 adrenergic agonists.
Capogrossi
M C
MC
Laboratory of Cardiovascular Science, Gerontology Research Center, Baltimore, MD 21224, USA.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000584:Amiloride / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D004146:Dioxanes / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D009200:Myocardial Contraction / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism*; D011493:Protein Kinase C / Q000378:metabolism; D011817:Rabbits; D012508:Sarcolemma / Q000187:drug effects* / Q000378:metabolism; D017923:Sodium-Hydrogen Exchangers / Q000187:drug effects* / Q000378:metabolism; D013268:Stimulation, Chemical
D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D000889:Anti-Arrhythmia Agents; D004146:Dioxanes; D017923:Sodium-Hydrogen Exchangers; D000584:Amiloride; C010654:(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane; D011493:Protein Kinase C; C039614:ethylisopropylamiloride