Long-term remission of previously resistant choriocarcinoma with a combination of etoposide, ifosfamide, and cisplatin.
A 30-year-old white female was diagnosed with gestational trophoblastic disease in 1981. Despite an original World Health Organization score of 4 and initial aggressive combination chemotherapy, she was treated over a 9-year period with multiple chemotherapy agents and had undergone several operative procedures to remove metastatic lesions for persistent disease. Long-term remission has now been obtained after four courses of etoposide, ifosfamide, and cisplatin.
Garris
P D
PD
Department of Obstetrics and Gynecology, Medical College of Georgia, Augusta 30912, USA.
Gallup
D G
DG
Melton
K
K
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002822:Choriocarcinoma / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D004351:Drug Resistance; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D012074:Remission Induction; D013997:Time Factors; D014594:Uterine Neoplasms / Q000188:drug therapy*
D005047:Etoposide; D002945:Cisplatin; D007069:Ifosfamide